TY - GEN T1 - Corrigendum to "Development and validation of a high-throughput online solid phase extraction - Liquid chromatography - Tandem mass spectrometry method for the detection of tetrodotoxin in human urine" [Toxicon 119 (2016) 64-71]. AN - 1852662279; 27951505 JF - Toxicon : official journal of the International Society on Toxinology AU - Coleman, Rebecca AU - Lemire, Sharon W AU - Bragg, William AU - Garrett, Alaine AU - Ojeda-Torres, Geovannie AU - Hamelin, Elizabeth AU - Johnson, Rudolph C AU - Thomas, Jerry Y1 - 2017/01// PY - 2017 DA - January 2017 SP - 120 VL - 125 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1852662279?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=Toxicon+%3A+official+journal+of+the+International+Society+on+Toxinology&rft.atitle=Corrigendum+to+%22Development+and+validation+of+a+high-throughput+online+solid+phase+extraction+-+Liquid+chromatography+-+Tandem+mass+spectrometry+method+for+the+detection+of+tetrodotoxin+in+human+urine%22+%5BToxicon+119+%282016%29+64-71%5D.&rft.au=Coleman%2C+Rebecca%3BLemire%2C+Sharon+W%3BBragg%2C+William%3BGarrett%2C+Alaine%3BOjeda-Torres%2C+Geovannie%3BHamelin%2C+Elizabeth%3BJohnson%2C+Rudolph+C%3BThomas%2C+Jerry&rft.aulast=Coleman&rft.aufirst=Rebecca&rft.date=2017-01-01&rft.volume=125&rft.issue=&rft.spage=120&rft.isbn=&rft.btitle=&rft.title=Toxicon+%3A+official+journal+of+the+International+Society+on+Toxinology&rft.issn=1879-3150&rft_id=info:doi/10.1016%2Fj.toxicon.2016.10.015 LA - English DB - ProQuest Environmental Science Collection N1 - Date created - 2016-12-12 N1 - Date revised - 2017-01-14 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1016/j.toxicon.2016.10.015 ER - TY - JOUR T1 - The impact of perceived intensity and frequency of police work occupational stressors on the cortisol awakening response (CAR): Findings from the BCOPS study. AN - 1837025413; 27816820 AB - Police officers encounter unpredictable, evolving, and escalating stressful demands in their work. Utilizing the Spielberger Police Stress Survey (60-item instrument for assessing specific conditions or events considered to be stressors in police work), the present study examined the association of the top five highly rated and bottom five least rated work stressors among police officers with their awakening cortisol pattern. Participants were police officers enrolled in the Buffalo Cardio-Metabolic Occupational Police Stress (BCOPS) study (n=338). For each group, the total stress index (product of rating and frequency of the stressor) was calculated. Participants collected saliva by means of Salivettes at four time points: on awakening, 15, 30 and 45min after waking to examine the cortisol awakening response (CAR). Saliva samples were analyzed for free cortisol concentrations. A slope reflecting the awakening pattern of cortisol over time was estimated by fitting a linear regression model relating cortisol in log-scale to time of collection. The slope served as the outcome variable. Analysis of covariance, regression, and repeated measures models were used to determine if there was an association of the stress index with the waking cortisol pattern. There was a significant negative linear association between total stress index of the five highest stressful events and slope of the awakening cortisol regression line (trend p-value=0.0024). As the stress index increased, the pattern of the awakening cortisol regression line tended to flatten. Officers with a zero stress index showed a steep and steady increase in cortisol from baseline (which is often observed) while officers with a moderate or high stress index showed a dampened or flatter response over time. Conversely, the total stress index of the five least rated events was not significantly associated with the awakening cortisol pattern. The study suggests that police events or conditions considered highly stressful by the officers may be associated with disturbances of the typical awakening cortisol pattern. The results are consistent with previous research where chronic exposure to stressors is associated with a diminished awakening cortisol response pattern. Copyright © 2016 Elsevier Ltd. All rights reserved. JF - Psychoneuroendocrinology AU - Violanti, John M AU - Fekedulegn, Desta AU - Andrew, Michael E AU - Hartley, Tara A AU - Charles, Luenda E AU - Miller, Diane B AU - Burchfiel, Cecil M AD - Department of Epidemiology and Environmental Health, School of Public Health and Health Professions, University at Buffalo, The State University of New York, Buffalo, NY, USA. Electronic address: violanti@buffalo.edu. ; Biostatistics and Epidemiology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV, USA. Electronic address: djf7@cdc.gov. ; Biostatistics and Epidemiology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV, USA. Electronic address: mta6@cdc.gov. ; Biostatistics and Epidemiology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV, USA. Electronic address: tow9@cdc.gov. ; Biostatistics and Epidemiology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV, USA. Electronic address: ley0@cdc.gov. ; Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV, USA. Electronic address: dum6@cdc.gov. ; Biostatistics and Epidemiology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV, USA. Electronic address: zar5@cdc.gov. Y1 - 2017/01// PY - 2017 DA - January 2017 SP - 124 EP - 131 VL - 75 KW - CAR KW - Police KW - Psychosocial stress UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1837025413?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Psychoneuroendocrinology&rft.atitle=The+impact+of+perceived+intensity+and+frequency+of+police+work+occupational+stressors+on+the+cortisol+awakening+response+%28CAR%29%3A+Findings+from+the+BCOPS+study.&rft.au=Violanti%2C+John+M%3BFekedulegn%2C+Desta%3BAndrew%2C+Michael+E%3BHartley%2C+Tara+A%3BCharles%2C+Luenda+E%3BMiller%2C+Diane+B%3BBurchfiel%2C+Cecil+M&rft.aulast=Violanti&rft.aufirst=John&rft.date=2017-01-01&rft.volume=75&rft.issue=&rft.spage=124&rft.isbn=&rft.btitle=&rft.title=Psychoneuroendocrinology&rft.issn=1873-3360&rft_id=info:doi/10.1016%2Fj.psyneuen.2016.10.017 LA - English DB - ProQuest Environmental Science Collection N1 - Date created - 2016-11-06 N1 - Date revised - 2017-01-14 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1016/j.psyneuen.2016.10.017 ER - TY - JOUR T1 - Prevalence and Correlates of Heterosexual Anal Intercourse Among Men and Women, 20 U.S. Cities AN - 1846418425; PQ0003886097 AB - Heterosexual anal intercourse (HAI) is not an uncommon behavior and it confers a higher risk of HIV transmission than vaginal intercourse. We examined data from heterosexuals recruited in 20 US cities for the 2013 National HIV Behavioral Surveillance system. We assessed correlates of reporting HAI in the previous year. Then, among people reporting HAI in the past year, we assessed what event-level factors are associated with having HAI at last sex. Thirty percent of women and 35 % of men reported HAI in the past year. Among people who had HAI in the past year, those who had HAI at last sex were more likely to have a partner who was HIV-positive or of unknown status or to have exchanged money or drugs for sex at last sex. Information that highlights the risk of HIV transmission associated with HAI would complement existing HIV prevention messages focused on heterosexuals in the U.S.Original Abstract: El sexo anal heterosexual (SAH) no es un comportamiento inusual y confiere un mayor riesgo de transmision del VIH que el coito vaginal. Hemos examinado los datos de heterosexuales reclutados en 20 ciudades de los EEUU para el 2013 provenientes del Sistema Nacional de Vigilancia del Comportamiento del VIH. Evaluamos las variables asociadas con el reporte de SAH en el ultimo ano. Asi mismo, evaluamos en aquellos que reportaron SAH en el ultimo ano, los factores asociados con SAH durante el ultimo acto sexual. El treinta por ciento de mujeres y un 35 % de los hombres reporto SAH en el ultimo ano. Entre las personas que reportaron SAH en el ultimo ano, quienes reportaron SAH durante el ultimo acto sexual eran mas propensos a tener una pareja sexual VIH-positiva o de estado, o reportar haber intercambiado sexo por dinero o drogas durante el ultimo acto sexual. Informacion que pone en relieve el riesgo de transmision del VIH asociado con SAH complementaria los mensajes de prevencion del VIH en heterosexuales en los EE.UU. JF - AIDS and Behavior AU - Hess, Kristen L AU - DiNenno, Elizabeth AU - Sionean, Catlainn AU - Ivy, Wade AU - Paz-Bailey, Gabriela AD - Division of HIV/AIDS Prevention, National Center for HIV, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Rd, MS-E47, Atlanta, GA, 30329, USA, xgm0@cdc.gov Y1 - 2016/12// PY - 2016 DA - December 2016 SP - 2966 EP - 2975 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 20 IS - 12 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Risk assessment KW - Acquired immune deficiency syndrome KW - Males KW - Retroviridae KW - Risk taking KW - Disease transmission KW - Cities KW - Prevention KW - Lentivirus KW - Risk factors KW - Females KW - Drugs KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1846418425?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Prevalence+and+Correlates+of+Heterosexual+Anal+Intercourse+Among+Men+and+Women%2C+20+U.S.+Cities&rft.au=Hess%2C+Kristen+L%3BDiNenno%2C+Elizabeth%3BSionean%2C+Catlainn%3BIvy%2C+Wade%3BPaz-Bailey%2C+Gabriela&rft.aulast=Hess&rft.aufirst=Kristen&rft.date=2016-12-01&rft.volume=20&rft.issue=12&rft.spage=2966&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-016-1295-z LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-12-01 N1 - Number of references - 30 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Risk assessment; Cities; Prevention; Acquired immune deficiency syndrome; Males; Risk factors; Risk taking; Females; Drugs; Disease transmission; Lentivirus; Retroviridae DO - http://dx.doi.org/10.1007/s10461-016-1295-z ER - TY - JOUR T1 - Delivery of HIV Transmission Risk-Reduction Services by HIV Care Providers in the United States-2013 AN - 1846412163; PQ0003843922 AB - Objectives: Evidence-based guidelines have long recommended that HIV care providers deliver HIV transmission risk-reduction (RR) services, but recent data are needed to assess their adoption. Methods: The authors surveyed a probability sample of 1234 US HIV care providers on delivery of 9 sexual behavior- and 7 substance use-related HIV transmission RR services and created an indicator of "adequate" delivery of services in each area, defined as performing approximately 70% or more of applicable services. Results: Providers were most likely to encourage patients to disclose HIV status to all partners since HIV diagnosis (81%) and least likely to ask about disclosure to new sex and drug injection partners at follow-up visits (both 41%). Adequate delivery of sexual behavior- and substance use-related RR services was low (37% and 43%, respectively). Conclusion: The majority of US HIV care providers may need additional support to improve delivery of comprehensive HIV transmission RR services. JF - Journal of the International Association of Providers of AIDS Care (JIAPAC) AU - Beer, Linda AU - Weiser, John AU - West, Brady T AU - Duke, Chris AU - Gremel, Garrett AU - Skarbinski, Jacek AD - 1 .Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA, lbeer@cdc.gov Y1 - 2016/11// PY - 2016 DA - November 2016 SP - 494 EP - 504 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU United Kingdom VL - 15 IS - 6 SN - 2325-9574, 2325-9574 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - HIV risk reduction KW - risk-reduction counseling KW - provider survey KW - prevention with positives KW - Acquired immune deficiency syndrome KW - Lentivirus KW - Retroviridae KW - Guidelines KW - Risk reduction KW - Drugs KW - Disease transmission KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1846412163?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+International+Association+of+Providers+of+AIDS+Care+%28JIAPAC%29&rft.atitle=Delivery+of+HIV+Transmission+Risk-Reduction+Services+by+HIV+Care+Providers+in+the+United+States-2013&rft.au=Beer%2C+Linda%3BWeiser%2C+John%3BWest%2C+Brady+T%3BDuke%2C+Chris%3BGremel%2C+Garrett%3BSkarbinski%2C+Jacek&rft.aulast=Beer&rft.aufirst=Linda&rft.date=2016-11-01&rft.volume=15&rft.issue=6&rft.spage=494&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+International+Association+of+Providers+of+AIDS+Care+%28JIAPAC%29&rft.issn=23259574&rft_id=info:doi/10.1177%2F2325957415612128 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-12-01 N1 - Number of references - 37 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Acquired immune deficiency syndrome; Guidelines; Risk reduction; Drugs; Disease transmission; Lentivirus; Retroviridae DO - http://dx.doi.org/10.1177/2325957415612128 ER - TY - JOUR T1 - Polychlorinated biphenyls: New evidence from the last decade AN - 1846411882; PQ0003839762 AB - Millions of pounds of polychlorinated biphenyl (PCB) compounds have been produced in multiple countries for industrial applications over the last several decades. PCB exposure induces various adverse health effects in animals and humans. Environmental and occupational exposures to PCBs have been associated with liver, kidney, endocrine, and neurodevelopmental adverse effects. We have collected and reviewed animal and human data cited in the US National Library of Medicine from 2000 to 2010. In brief, our review shows new evidence, that is, in animal studies, exposure to one of the PCBs, A1221, induces a significant alteration of serum luteinizing hormone. The effects were more profound in the F2 generation, particularly with respect to fluctuations in hormones and reproductive tract tissues across the estrous cycle. Morphological analyses of brain tissue from rats exposed to A1254 confirmed the results of an earlier work which showed that the relative size of the intra- and infrapyramidal (II-P) mossy fibers was smaller than that in the controls and also reduction in growth was selective for the II-P mossy fibers. PCB exposure increased anogenital distance and prostate size but decreased epididymal weight, epididymal sperm count, and motile epididymal sperm count. No effects were observed on testicular weight or size. The epidemiological data showed an association between diabetes mellitus prevalence and elevated concentrations of PCB 153. Additionally, prenatal PCB exposure studies were associated with a smaller thymic index at birth and could adversely affect immune responses to childhood vaccinations and resistance to respiratory infections. PCB exposure was also reported to adversely affect enamel development in children in a dose-dependent manner. Because PCBs and their metabolites are potential health hazards, understanding the risk factors associated with individual PCBs, PCB mixtures, and PCB metabolites is important. PCB exposures of vulnerable populations (pregnant women, fetuses, infants, and children) are of particular concern because of heightened sensitivity during this period of brain development. JF - Toxicology and Industrial Health AU - Faroon, Obaid AU - Ruiz, Patricia AD - Division of Toxicology and Human Health Sciences, Agency for Toxic Substances and Disease Registry, Atlanta, GA, USA, oxs0@cdc.gov Y1 - 2016/11// PY - 2016 DA - November 2016 SP - 1825 EP - 1847 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU United Kingdom VL - 32 IS - 11 SN - 0748-2337, 0748-2337 KW - Health & Safety Science Abstracts; Toxicology Abstracts KW - cancer KW - developmental neurotoxicity KW - diabetes mellitus KW - endocrine disrupters KW - PCB congeners KW - Polychlorinated biphenyls KW - Prenatal experience KW - Metabolites KW - Sperm KW - Infection KW - Hormones KW - Reproductive system KW - Vulnerability KW - PCB compounds KW - PCB KW - Occupational exposure KW - Sensitivity KW - Data processing KW - Thymus KW - Brain KW - Children KW - Pregnancy KW - Diabetes mellitus KW - polychlorinated biphenyls KW - mossy fibers KW - Reviews KW - Kidney KW - Vaccines KW - Immune response KW - Infants KW - H 1000:Occupational Safety and Health KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1846411882?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+Industrial+Health&rft.atitle=Polychlorinated+biphenyls%3A+New+evidence+from+the+last+decade&rft.au=Faroon%2C+Obaid%3BRuiz%2C+Patricia&rft.aulast=Faroon&rft.aufirst=Obaid&rft.date=2016-11-01&rft.volume=32&rft.issue=11&rft.spage=1825&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+Industrial+Health&rft.issn=07482337&rft_id=info:doi/10.1177%2F0748233715587849 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-12-01 N1 - Number of references - 102 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Prenatal experience; Data processing; Thymus; Brain; Metabolites; Sperm; Children; Infection; Hormones; Reproductive system; Pregnancy; polychlorinated biphenyls; Reviews; mossy fibers; Kidney; Immune response; Occupational exposure; PCB; Infants; Sensitivity; Diabetes mellitus; Vulnerability; Vaccines; PCB compounds DO - http://dx.doi.org/10.1177/0748233715587849 ER - TY - JOUR T1 - High-throughput and sensitive analysis of urinary heterocyclic aromatic amines using isotope-dilution liquid chromatography-tandem mass spectrometry and robotic sample preparation system AN - 1837296273; PQ0003770360 AB - Heterocyclic aromatic amines (HCAA) are listed by the US Food and Drug Administration (FDA) as harmful or potentially harmful constituents of tobacco smoke. However, quantifying HCAA exposure is challenging. In this study, we developed a sensitive, precise, and accurate isotope dilution, liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to quantify urinary HCAAs in smokers and nonsmokers. The high-throughput robotic sample preparation system could handle a throughput of over 300 samples per day, while maintaining intra-day and inter-day imprecision and bias less than or equal to 10 %. The limits of detection of carcinogenic HCAAs ranged from 0.31 to 0.83 pg/mL. The validated method was applied to measure HCAAs in urine collected from smokers and non-smokers. This sensitive and efficient analytical method is ideal to support large-scale biomonitoring studies of HCAA exposure. [Figure not available: see fulltext.] JF - Analytical and Bioanalytical Chemistry AU - Zhang, Li AU - Xia, Yang AU - Xia, Baoyun AU - Nicodemus, Keegan J AU - McGuffey, James AU - McGahee, Ernest AU - Blount, Benjamin AU - Wang, Lanqing AD - Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway Mail Stop F47, Atlanta, GA, 30341, USA, lzhang6@cdc.gov Y1 - 2016/11// PY - 2016 DA - November 2016 SP - 8149 EP - 8161 PB - Springer Science+Business Media, Berlin/Heidelberg Germany VL - 408 IS - 28 SN - 1618-2642, 1618-2642 KW - Biotechnology and Bioengineering Abstracts KW - Smoke KW - amines KW - Isotopes KW - Urine KW - Tobacco KW - biomonitoring KW - robotics KW - Aromatics KW - Mass spectroscopy KW - W 30935:Food Biotechnology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1837296273?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytical+and+Bioanalytical+Chemistry&rft.atitle=High-throughput+and+sensitive+analysis+of+urinary+heterocyclic+aromatic+amines+using+isotope-dilution+liquid+chromatography-tandem+mass+spectrometry+and+robotic+sample+preparation+system&rft.au=Zhang%2C+Li%3BXia%2C+Yang%3BXia%2C+Baoyun%3BNicodemus%2C+Keegan+J%3BMcGuffey%2C+James%3BMcGahee%2C+Ernest%3BBlount%2C+Benjamin%3BWang%2C+Lanqing&rft.aulast=Zhang&rft.aufirst=Li&rft.date=2016-11-01&rft.volume=408&rft.issue=28&rft.spage=8149&rft.isbn=&rft.btitle=&rft.title=Analytical+and+Bioanalytical+Chemistry&rft.issn=16182642&rft_id=info:doi/10.1007%2Fs00216-016-9917-x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-11-01 N1 - Number of references - 30 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Smoke; Isotopes; amines; Urine; Tobacco; biomonitoring; robotics; Mass spectroscopy; Aromatics DO - http://dx.doi.org/10.1007/s00216-016-9917-x ER - TY - JOUR T1 - Enhanced Surveillance for Fatal Dengue-Like Acute Febrile Illness in Puerto Rico, 2010-2012. AN - 1835380982; 27727271 AB - Dengue is a leading cause of morbidity throughout the tropics; however, accurate population-based estimates of mortality rates are not available. We established the Enhanced Fatal Acute Febrile Illness Surveillance System (EFASS) to estimate dengue mortality rates in Puerto Rico. Healthcare professionals submitted serum and tissue specimens from patients who died from a dengue-like acute febrile illness, and death certificates were reviewed to identify additional cases. Specimens were tested for markers of dengue virus (DENV) infection by molecular, immunologic, and immunohistochemical methods, and were also tested for West Nile virus, Leptospira spp., and other pathogens based on histopathologic findings. Medical records were reviewed and clinical data abstracted. A total of 311 deaths were identified, of which 58 (19%) were DENV laboratory-positive. Dengue mortality rates were 1.05 per 100,000 population in 2010, 0.16 in 2011 and 0.36 in 2012. Dengue mortality was highest among adults 19-64 years and seniors ≥65 years (1.17 and 1.66 deaths per 100,000, respectively). Other pathogens identified included 34 Leptospira spp. cases and one case of Burkholderia pseudomallei and Neisseria meningitidis. EFASS showed that dengue mortality rates among adults were higher than reported for influenza, and identified a leptospirosis outbreak and index cases of melioidosis and meningitis. JF - PLoS neglected tropical diseases AU - Tomashek, Kay M AU - Rivera, Aidsa AU - Torres-Velasquez, Brenda AU - Hunsperger, Elizabeth A AU - Munoz-Jordan, Jorge L AU - Sharp, Tyler M AU - Rivera, Irma AU - Sanabria, Dario AU - Blau, Dianna M AU - Galloway, Renee AU - Torres, Jose AU - Rodriguez, Rosa AU - Serrano, Javier AU - Chávez, Carlos AU - Dávila, Francisco AU - Perez-Padilla, Janice AU - Ellis, Esther M AU - Caballero, Gladys AU - Wright, Laura AU - Zaki, Sherif R AU - Deseda, Carmen AU - Rodriguez, Edda AU - Margolis, Harold S AD - Dengue Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention (CDC), San Juan, Puerto Rico. ; Puerto Rico Institute of Forensic Sciences, San Juan, Puerto Rico. ; Infectious Diseases Pathology Branch, Division of High Consequence Pathogens and Pathology, CDC, Atlanta, Georgia, United States of America. ; Bacterial Special Pathogens Branch, Division of High Consequence Pathogens, CDC, Atlanta, Georgia, United States of America. ; Demographic Registry of Puerto Rico, San Juan, Puerto Rico. ; Geospatial Research, Analysis, and Services Program, Division of Toxicology and Human Health Sciences, ATSDR, Atlanta, Georgia, United States of America. ; Puerto Rico Department of Health, San Juan, Puerto Rico. Y1 - 2016/10// PY - 2016 DA - October 2016 SP - 1 VL - 10 IS - 10 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1835380982?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=PLoS+neglected+tropical+diseases&rft.atitle=Enhanced+Surveillance+for+Fatal+Dengue-Like+Acute+Febrile+Illness+in+Puerto+Rico%2C+2010-2012.&rft.au=Tomashek%2C+Kay+M%3BRivera%2C+Aidsa%3BTorres-Velasquez%2C+Brenda%3BHunsperger%2C+Elizabeth+A%3BMunoz-Jordan%2C+Jorge+L%3BSharp%2C+Tyler+M%3BRivera%2C+Irma%3BSanabria%2C+Dario%3BBlau%2C+Dianna+M%3BGalloway%2C+Renee%3BTorres%2C+Jose%3BRodriguez%2C+Rosa%3BSerrano%2C+Javier%3BCh%C3%A1vez%2C+Carlos%3BD%C3%A1vila%2C+Francisco%3BPerez-Padilla%2C+Janice%3BEllis%2C+Esther+M%3BCaballero%2C+Gladys%3BWright%2C+Laura%3BZaki%2C+Sherif+R%3BDeseda%2C+Carmen%3BRodriguez%2C+Edda%3BMargolis%2C+Harold+S&rft.aulast=Tomashek&rft.aufirst=Kay&rft.date=2016-10-01&rft.volume=10&rft.issue=10&rft.spage=e0005025&rft.isbn=&rft.btitle=&rft.title=PLoS+neglected+tropical+diseases&rft.issn=1935-2735&rft_id=info:doi/10.1371%2Fjournal.pntd.0005025 LA - English DB - ProQuest Environmental Science Collection N1 - Date created - 2016-10-11 N1 - Date revised - 2017-01-14 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1371/journal.pntd.0005025 ER - TY - JOUR T1 - Prevalence of HIV Among U.S. Female Sex Workers: Systematic Review and Meta-analysis AN - 1827935067; PQ0003689574 AB - Although female sex workers are known to be vulnerable to HIV infection, little is known about the epidemiology of HIV infection among this high-risk population in the United States. We systematically identified and critically assessed published studies reporting HIV prevalence among female sex workers in the United States. We searched for and included original English-language articles reporting data on the prevalence of HIV as determined by testing at least 50 females who exchanged sexual practices for money or drugs. We did not apply any restrictions on date of publication. We included 14 studies from 1987 to 2013 that reported HIV prevalence for a total of 3975 adult female sex workers. Only two of the 14 studies were conducted in the last 10 years. The pooled estimate of HIV prevalence was 17.3 % (95 % CI 13.5-21.9 %); however, the prevalence of HIV across individual studies varied considerably (ranging from 0.3 to 32 %) and statistical heterogeneity was substantial (I super(2) = 0.89, Q = 123; p < 0.001). Although the variance across the 14 studies was high, prevalence was generally high (10 % or greater in 11 of the 14 included studies). Very few studies have documented the prevalence of HIV among female sex workers in the United States; however, the available evidence does suggest that HIV prevalence among this vulnerable population is high. JF - AIDS and Behavior AU - Paz-Bailey, Gabriela AU - Noble, Meredith AU - Salo, Kathryn AU - Tregear, Stephen J AD - Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, MS E-46, Atlanta, GA, 30329, USA, gmb5@cdc.gov Y1 - 2016/10// PY - 2016 DA - October 2016 SP - 2318 EP - 2331 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 20 IS - 10 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Acquired immune deficiency syndrome KW - Data processing KW - Statistics KW - Retroviridae KW - Prostitution KW - Infection KW - USA KW - Lentivirus KW - Epidemiology KW - Reviews KW - Risk groups KW - Vulnerability KW - Females KW - Drugs KW - V 22360:AIDS and HIV KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1827935067?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Prevalence+of+HIV+Among+U.S.+Female+Sex+Workers%3A+Systematic+Review+and+Meta-analysis&rft.au=Paz-Bailey%2C+Gabriela%3BNoble%2C+Meredith%3BSalo%2C+Kathryn%3BTregear%2C+Stephen+J&rft.aulast=Paz-Bailey&rft.aufirst=Gabriela&rft.date=2016-10-01&rft.volume=20&rft.issue=10&rft.spage=2318&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-016-1332-y LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-10-01 N1 - Number of references - 50 N1 - Last updated - 2016-10-26 N1 - SubjectsTermNotLitGenreText - Statistics; Data processing; Epidemiology; Reviews; Risk groups; Prostitution; Infection; Drugs; Acquired immune deficiency syndrome; Females; Vulnerability; Lentivirus; Retroviridae; USA DO - http://dx.doi.org/10.1007/s10461-016-1332-y ER - TY - JOUR T1 - Multiplex assay for subtyping avian influenza A viruses by cDNA hybridization and adapter-mediated amplification AN - 1827917357; PQ0003710503 AB - Multiple subtypes of influenza A viruses circulating in animals must be closely monitored to understand their risk to humans and animal populations. Many molecular-based subtyping methods require constant monitoring of viral genomes for primer and/or probe mismatches and are prone to primer-primer interactions. This report presents a new approach that involves target enrichment through cDNA hybridization followed by adapter-mediated amplification for subtyping influenza virus (AmASIV). As a proof of concept, the AmASIV assay was multiplexed to specifically detect and differentiate influenza A virus subtypes (H5, N5, N7, and N9) in a single reaction without cross-recognition of nontarget subtypes or influenza B virus. The limit of detection (LOD) of AmASIV, as measured by 50 % egg-infective dose per reaction (EID sub(50)/reaction), was comparable to that of singleplex TaqMan registered qPCR assays with LODs of 10 super(-0.6) (H5), 10 super(2) (N5), 10 super(-0.3) (N7), and 10 super(-0.5) (N9) EID sub(50)/reaction. The AmASIV will strengthen animal influenza virus surveillance and laboratory capacity to improve prevention and control of influenza. JF - Applied Microbiology and Biotechnology AU - Yang, Genyan AU - Jones, Joyce AU - Jang, Yunho AU - Davis, CTodd AD - Influenza Division, Virology, Surveillance and Diagnosis Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, MS-D30, Atlanta, GA, 30333, USA, eou8@cdc.gov Y1 - 2016/10// PY - 2016 DA - October 2016 SP - 8809 EP - 8818 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 100 IS - 20 SN - 0175-7598, 0175-7598 KW - Virology & AIDS Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology; Biotechnology and Bioengineering Abstracts KW - Genomes KW - Fowl plague KW - Influenza A virus KW - DNA probes KW - Influenza A KW - Primers KW - Orthomyxoviridae KW - Influenza B virus KW - V 22300:Methods KW - W 30900:Methods KW - A 01300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1827917357?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+Microbiology+and+Biotechnology&rft.atitle=Multiplex+assay+for+subtyping+avian+influenza+A+viruses+by+cDNA+hybridization+and+adapter-mediated+amplification&rft.au=Yang%2C+Genyan%3BJones%2C+Joyce%3BJang%2C+Yunho%3BDavis%2C+CTodd&rft.aulast=Yang&rft.aufirst=Genyan&rft.date=2016-10-01&rft.volume=100&rft.issue=20&rft.spage=8809&rft.isbn=&rft.btitle=&rft.title=Applied+Microbiology+and+Biotechnology&rft.issn=01757598&rft_id=info:doi/10.1007%2Fs00253-016-7664-8 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-10-01 N1 - Number of references - 26 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Genomes; Fowl plague; Influenza A; DNA probes; Primers; Influenza A virus; Orthomyxoviridae; Influenza B virus DO - http://dx.doi.org/10.1007/s00253-016-7664-8 ER - TY - JOUR T1 - Nutrition and Physical Activity Strategies for Cancer Prevention in Current National Comprehensive Cancer Control Program Plans AN - 1827889966; PQ0003687047 AB - Obesity, diet and physical inactivity are risk factors for some cancers. Grantees of the National Comprehensive Cancer Control Program (NCCCP) in US states, tribes, and territories develop plans to coordinate funding and activities for cancer prevention and control. Including information and goals related to nutrition and physical activity (NPA) is a key opportunity for primary cancer prevention, but it is currently unclear to what extent NCCCP plans address these issues. We reviewed 69 NCCCP plans and searched for terms related to NPA. Plans were coded as (1) knowledge of NPA and cancer link; (2) goals to improve NPA behaviors; and (3) strategies to increase healthy NPA activities, environments, or systems changes. NPA content was consistently included in all cancer plans examined across all years. Only 4 (6 %) outlined only the relationship between NPA and cancer without goals or strategies. Fifty-nine plans (89 %) contained goals or strategies related to NPA, with 53 (82 %) including both. However, numbers of goals, strategies, and detail provided varied widely. All programs recognized the importance of NPA in cancer prevention. Most plans included NPA goals and strategies. Increasing the presence of NPA strategies that can be modified or adapted appropriately locally could help with more widespread implementation and measurement of NPA interventions. JF - Journal of Community Health AU - Puckett, Mary AU - Neri, Antonio AU - Underwood, JMichael AU - Stewart, Sherri L AD - Division of Cancer Prevention and Control, Comprehensive Cancer Control Branch, Centers for Disease Control and Prevention, 4770 Buford Highway, MS F-76, Atlanta, GA, 30341, USA, xdg6@cdc.gov Y1 - 2016/10// PY - 2016 DA - October 2016 SP - 1013 EP - 1020 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 41 IS - 5 SN - 0094-5145, 0094-5145 KW - Health & Safety Science Abstracts KW - Diets KW - Health risks KW - Obesity KW - Prevention KW - Physical activity KW - Risk factors KW - Intervention KW - Territory KW - Nutrition KW - Cancer KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1827889966?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Community+Health&rft.atitle=Nutrition+and+Physical+Activity+Strategies+for+Cancer+Prevention+in+Current+National+Comprehensive+Cancer+Control+Program+Plans&rft.au=Puckett%2C+Mary%3BNeri%2C+Antonio%3BUnderwood%2C+JMichael%3BStewart%2C+Sherri+L&rft.aulast=Puckett&rft.aufirst=Mary&rft.date=2016-10-01&rft.volume=41&rft.issue=5&rft.spage=1013&rft.isbn=&rft.btitle=&rft.title=Journal+of+Community+Health&rft.issn=00945145&rft_id=info:doi/10.1007%2Fs10900-016-0184-8 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-10-01 N1 - Number of references - 50 N1 - Last updated - 2016-10-26 N1 - SubjectsTermNotLitGenreText - Diets; Obesity; Health risks; Prevention; Risk factors; Physical activity; Intervention; Territory; Nutrition; Cancer DO - http://dx.doi.org/10.1007/s10900-016-0184-8 ER - TY - JOUR T1 - The Role of Structural Barriers in Risky Sexual Behavior, Victimization and Readiness to Change HIV/STI-Related Risk Behavior Among Transgender Women AN - 1827884289; PQ0003689586 AB - This study examines the role of structural barriers experienced by a community-based sample of 63 HIV-positive and negative transgender women that may elevate HIV infection and transmission risks. Separate hierarchical linear multiple regression analyses tested the association between structural barriers (e.g., unemployment, lack of food, shelter) and condomless anal sex acts, abuse, and readiness to change risk behavior, while controlling for other related factors. Among this primarily Hispanic and African-American sample, HIV-positive and negative transgender women experienced a similar number of structural barriers and experiencing structural barriers was significantly associated with an increased number of condomless anal sex acts (p = .002), victimization (p = .000) and a decreased readiness to change HIV-related risk behavior (p = .014). Structural-level interventions are needed to address this elevated risk among this underserved and hard-to-reach population. JF - AIDS and Behavior AU - Raiford, Jerris L AU - Hall, Grace J AU - Taylor, Raekiela D AU - Bimbi, David S AU - Parsons, Jeffrey T AD - Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA, jraiford@cdc.gov Y1 - 2016/10// PY - 2016 DA - October 2016 SP - 2212 EP - 2221 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 20 IS - 10 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Acquired immune deficiency syndrome KW - anal sex KW - Unemployment KW - Community involvement KW - Food KW - Retroviridae KW - Risk taking KW - Intervention KW - Multiple regression analysis KW - Shelter KW - Infection KW - Sexual behavior KW - Abuse KW - Disease transmission KW - Health risks KW - Lentivirus KW - Risk factors KW - Bisexuality KW - Females KW - Victimization KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1827884289?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=The+Role+of+Structural+Barriers+in+Risky+Sexual+Behavior%2C+Victimization+and+Readiness+to+Change+HIV%2FSTI-Related+Risk+Behavior+Among+Transgender+Women&rft.au=Raiford%2C+Jerris+L%3BHall%2C+Grace+J%3BTaylor%2C+Raekiela+D%3BBimbi%2C+David+S%3BParsons%2C+Jeffrey+T&rft.aulast=Raiford&rft.aufirst=Jerris&rft.date=2016-10-01&rft.volume=20&rft.issue=10&rft.spage=2212&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-016-1424-8 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-10-01 N1 - Number of references - 40 N1 - Last updated - 2016-10-26 N1 - SubjectsTermNotLitGenreText - anal sex; Food; Multiple regression analysis; Shelter; Infection; Sexual behavior; Abuse; Disease transmission; Health risks; Acquired immune deficiency syndrome; Unemployment; Community involvement; Bisexuality; Risk factors; Intervention; Risk taking; Females; Victimization; Lentivirus; Retroviridae DO - http://dx.doi.org/10.1007/s10461-016-1424-8 ER - TY - JOUR T1 - Latent Tuberculosis Infection Among Immigrant and Refugee Children Arriving in the United States: 2010 AN - 1815710657; PQ0003591838 AB - Immigrants and refugees age 2-14 years entering the United States from countries with estimated tuberculosis (TB) incidence rate greater than or equal to 20 per 100,000 population are screened for TB. Children with TB disease are treated before US arrival. Children with positive tuberculin skin tests (TST), but negative TB evaluation during their pre-immigration examination, are classified with latent TB infection (LTBI) and are recommended for re-evaluation post-arrival. We examined post-immigration TB evaluation and therapy for children arriving with LTBI. We reviewed medical exam data from immigrant children with medical conditions and all refugee children arriving during 2010. Medical examination data were available for 67,334 children. Of these, 8231 (12 %) had LTBI pre-immigration; 5749 (70 %) were re-evaluated for TB post-immigration, and 64 % were retested by TST or IGRA. The pre-immigration LTBI diagnosis was changed for 38 % when retested by TST and for 71 % retested by IGRA. Estimated LTBI therapy initiation and completion rates were 68 and 12 %. In this population, testing with IGRA may limit the number of children targeted for therapy. Increased pre-immigration TB screening with post-immigration follow-up evaluation leading to completion of LTBI therapy should be encouraged to prevent TB reactivation. JF - Journal of Immigrant and Minority Health AU - Taylor, Eboni M AU - Painter, John AU - Posey, Drew L AU - Zhou, Weigong AU - Shetty, Sharmila AD - Division of Global Migration and Quarantine, National Center of Emerging Zoonotic and Infectious Diseases, United States Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Mailstop E-04, Atlanta, GA, 30333, USA, ETaylor1@cdc.gov Y1 - 2016/10// PY - 2016 DA - October 2016 SP - 966 EP - 970 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 18 IS - 5 SN - 1557-1912, 1557-1912 KW - Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts KW - Age KW - Skin KW - Data processing KW - Mycobacterium KW - Immigrants KW - Children KW - Infection KW - Refugees KW - Skin tests KW - USA KW - Reviews KW - Tuberculosis KW - Tuberculin KW - J 02400:Human Diseases KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1815710657?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Immigrant+and+Minority+Health&rft.atitle=Latent+Tuberculosis+Infection+Among+Immigrant+and+Refugee+Children+Arriving+in+the+United+States%3A+2010&rft.au=Taylor%2C+Eboni+M%3BPainter%2C+John%3BPosey%2C+Drew+L%3BZhou%2C+Weigong%3BShetty%2C+Sharmila&rft.aulast=Taylor&rft.aufirst=Eboni&rft.date=2016-10-01&rft.volume=18&rft.issue=5&rft.spage=966&rft.isbn=&rft.btitle=&rft.title=Journal+of+Immigrant+and+Minority+Health&rft.issn=15571912&rft_id=info:doi/10.1007%2Fs10903-015-0273-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-08-01 N1 - Number of references - 20 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Age; Data processing; Reviews; Immigrants; Tuberculin; Tuberculosis; Infection; Children; Skin tests; Skin; Refugees; Mycobacterium; USA DO - http://dx.doi.org/10.1007/s10903-015-0273-2 ER - TY - JOUR T1 - Delivering Prevention Interventions to People Living with HIV in Clinical Care Settings: Results of a Cluster Randomized Trial in Kenya, Namibia, and Tanzania AN - 1819142951; PQ0003622462 AB - We conducted a group randomized trial to assess the feasibility and effectiveness of a multi-component, clinic-based HIV prevention intervention for HIV-positive patients attending clinical care in Namibia, Kenya, and Tanzania. Eighteen HIV care and treatment clinics (six per country) were randomly assigned to intervention or control arms. Approximately 200 sexually active clients from each clinic were enrolled and interviewed at baseline and 6- and 12-months post-intervention. Mixed model logistic regression with random effects for clinic and participant was used to assess the effectiveness of the intervention. Of 3522 HIV-positive patients enrolled, 3034 (86 %) completed a 12-month follow-up interview. Intervention participants were significantly more likely to report receiving provider-delivered messages on disclosure, partner testing, family planning, alcohol reduction, and consistent condom use compared to participants in comparison clinics. Participants in intervention clinics were less likely to report unprotected sex in the past 2 weeks (OR = 0.56, 95 % CI 0.32, 0.99) compared to participants in comparison clinics. In Tanzania, a higher percentage of participants in intervention clinics (17 %) reported using a highly effective method of contraception compared to participants in comparison clinics (10 %, OR = 2.25, 95 % CI 1.24, 4.10). This effect was not observed in Kenya or Namibia. HIV prevention services are feasible to implement as part of routine care and are associated with a self-reported decrease in unprotected sex. Further operational research is needed to identify strategies to address common operational challenges including staff turnover and large patient volumes. JF - AIDS and Behavior AU - Bachanas, Pamela AU - Kidder, Daniel AU - Medley, Amy AU - Pals, Sherri L AU - Carpenter, Deborah AU - Howard, Andrea AU - Antelman, Gretchen AU - DeLuca, Nicolas AU - Muhenje, Odylia AU - Sheriff, Muhsin AU - Somi, Geoffrey AU - Katuta, Frieda AU - Cherutich, Peter AU - Moore, Janet AD - Division of Global HIV/AIDS, U.S. Centers for Disease Control and Prevention, 1600 Clifton Road, MS E04, Atlanta, GA, 30333, USA, pbachanas@cdc.gov Y1 - 2016/09// PY - 2016 DA - September 2016 SP - 2110 EP - 2118 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 20 IS - 9 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Family planning KW - Feasibility studies KW - Alcohol KW - Acquired immune deficiency syndrome KW - Intervention KW - ISW, Tanzania KW - Clinical trials KW - Models KW - Condoms KW - Prevention KW - Kenya KW - Lentivirus KW - Contraception KW - Human immunodeficiency virus KW - Regression analysis KW - alcohols KW - Namibia KW - Sex KW - V 22360:AIDS and HIV KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1819142951?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Delivering+Prevention+Interventions+to+People+Living+with+HIV+in+Clinical+Care+Settings%3A+Results+of+a+Cluster+Randomized+Trial+in+Kenya%2C+Namibia%2C+and+Tanzania&rft.au=Bachanas%2C+Pamela%3BKidder%2C+Daniel%3BMedley%2C+Amy%3BPals%2C+Sherri+L%3BCarpenter%2C+Deborah%3BHoward%2C+Andrea%3BAntelman%2C+Gretchen%3BDeLuca%2C+Nicolas%3BMuhenje%2C+Odylia%3BSheriff%2C+Muhsin%3BSomi%2C+Geoffrey%3BKatuta%2C+Frieda%3BCherutich%2C+Peter%3BMoore%2C+Janet&rft.aulast=Bachanas&rft.aufirst=Pamela&rft.date=2016-09-01&rft.volume=20&rft.issue=9&rft.spage=2110&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-016-1349-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-09-01 N1 - Number of references - 22 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Condoms; Contraception; alcohols; Regression analysis; Clinical trials; Models; Sex; Feasibility studies; Family planning; Alcohol; Acquired immune deficiency syndrome; Prevention; Intervention; Lentivirus; Human immunodeficiency virus; Kenya; ISW, Tanzania; Namibia DO - http://dx.doi.org/10.1007/s10461-016-1349-2 ER - TY - JOUR T1 - Factors Associated with HIV Testing among African American Female Adolescents in Juvenile Detention Centers AN - 1819142646; PQ0003622456 AB - Little is known about sexual and psychosocial factors associated with HIV testing among detained African American female adolescents-an understudied group at risk for HIV. 188 detained African American female adolescents completed assessments on HIV testing, sexual risk behaviors, and psychosocial factors. Unprotected vaginal sex, history of STI-positivity or pregnancy, higher STI knowledge, and lower partner availability were associated with a higher likelihood of ever being tested for HIV. HIV testing is the gateway to important services for high-risk HIV-positive and HIV-negative adolescents. More research is needed to address barriers and to inform programmatic changes to increase testing among youth. JF - AIDS and Behavior AU - Seth, Puja AU - Raiford, Jerris AU - DiClemente, Ralph J AD - Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA, pseth@cdc.gov Y1 - 2016/09// PY - 2016 DA - September 2016 SP - 2010 EP - 2013 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 20 IS - 9 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Risk assessment KW - Historical account KW - Acquired immune deficiency syndrome KW - Adolescence KW - Risk taking KW - Sexual behavior KW - Pregnancy KW - Lentivirus KW - Human immunodeficiency virus KW - Risk factors KW - Vagina KW - Risk groups KW - Females KW - Ethnic groups KW - Adolescents KW - Sex KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1819142646?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Factors+Associated+with+HIV+Testing+among+African+American+Female+Adolescents+in+Juvenile+Detention+Centers&rft.au=Seth%2C+Puja%3BRaiford%2C+Jerris%3BDiClemente%2C+Ralph+J&rft.aulast=Seth&rft.aufirst=Puja&rft.date=2016-09-01&rft.volume=20&rft.issue=9&rft.spage=2010&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-016-1310-4 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-09-01 N1 - Number of references - 12 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Risk factors; Adolescence; Vagina; Risk groups; Sexual behavior; Pregnancy; Sex; Risk assessment; Historical account; Acquired immune deficiency syndrome; Risk taking; Females; Adolescents; Ethnic groups; Lentivirus; Human immunodeficiency virus DO - http://dx.doi.org/10.1007/s10461-016-1310-4 ER - TY - JOUR T1 - Epidemiology of Invasive Group A Streptococcal Infections in the United States, 2005-2012. AN - 1808607015; 27105747 AB - Invasive group A Streptococcus (GAS) infections are associated with significant morbidity and mortality rates. We report the epidemiology and trends of invasive GAS over 8 years of surveillance. From January 2005 through December 2012, we collected data from the Centers for Disease Control and Prevention's Active Bacterial Core surveillance, a population-based network of 10 geographically diverse US sites (2012 population, 32.8 million). We defined invasive GAS as isolation of GAS from a normally sterile site or from a wound in a patient with necrotizing fasciitis (NF) or streptococcal toxic shock syndrome (STSS). Available isolates were emm typed. We calculated rates and made age- and race-adjusted national projections using census data. We identified 9557 cases (3.8 cases per 100 000 persons per year) with 1116 deaths (case-fatality rate, 11.7%). The case-fatality rates for septic shock, STSS, and NF were 45%, 38%, and 29%, respectively. The annual incidence was highest among persons aged ≥65 years (9.4/100 000) or <1 year (5.3) and among blacks (4.7/100 000). National rates remained steady over 8 years of surveillance. Factors independently associated with death included increasing age, residence in a nursing home, recent surgery, septic shock, NF, meningitis, isolated bacteremia, pneumonia, emm type 1 or 3, and underlying chronic illness or immunosuppression. An estimated 10 649-13 434 cases of invasive GAS infections occur in the United States annually, resulting in 1136-1607 deaths. In a 30-valent M-protein vaccine, emm types accounted for 91% of isolates. The burden of invasive GAS infection in the United States remains substantial. Vaccines under development could have a considerable public health impact. © The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail journals.permissions@oup.com. JF - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America AU - Nelson, George E AU - Pondo, Tracy AU - Toews, Karrie-Ann AU - Farley, Monica M AU - Lindegren, Mary Lou AU - Lynfield, Ruth AU - Aragon, Deborah AU - Zansky, Shelley M AU - Watt, James P AU - Cieslak, Paul R AU - Angeles, Kathy AU - Harrison, Lee H AU - Petit, Susan AU - Beall, Bernard AU - Van Beneden, Chris A AD - Epidemic Intelligence Service National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention Vanderbilt University, Nashville, Tennessee. ; National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention. ; Emory University School of Medicine and the VA Medical Center, Atlanta, Georgia. ; Vanderbilt University, Nashville, Tennessee. ; Minnesota Department of Health, St Paul. ; Colorado Department of Public Health and Environment, Denver. ; New York State Department of Health, Albany. ; California Department of Public Health, Richmond. ; Oregon Health Authority, Portland. ; New Mexico Emerging Infections Program, University of New Mexico, Las Cruces. ; Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland. ; Connecticut Department of Public Health, Hartford. Y1 - 2016/08/15/ PY - 2016 DA - 2016 Aug 15 SP - 478 EP - 486 VL - 63 IS - 4 KW - Index Medicus KW - surveillance KW - group A Streptococcus KW - streptococcal toxic shock syndrome KW - epidemiology KW - vaccine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808607015?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+infectious+diseases+%3A+an+official+publication+of+the+Infectious+Diseases+Society+of+America&rft.atitle=Epidemiology+of+Invasive+Group+A+Streptococcal+Infections+in+the+United+States%2C+2005-2012.&rft.au=Nelson%2C+George+E%3BPondo%2C+Tracy%3BToews%2C+Karrie-Ann%3BFarley%2C+Monica+M%3BLindegren%2C+Mary+Lou%3BLynfield%2C+Ruth%3BAragon%2C+Deborah%3BZansky%2C+Shelley+M%3BWatt%2C+James+P%3BCieslak%2C+Paul+R%3BAngeles%2C+Kathy%3BHarrison%2C+Lee+H%3BPetit%2C+Susan%3BBeall%2C+Bernard%3BVan+Beneden%2C+Chris+A&rft.aulast=Nelson&rft.aufirst=George&rft.date=2016-08-15&rft.volume=63&rft.issue=4&rft.spage=478&rft.isbn=&rft.btitle=&rft.title=Clinical+infectious+diseases+%3A+an+official+publication+of+the+Infectious+Diseases+Society+of+America&rft.issn=1537-6591&rft_id=info:doi/10.1093%2Fcid%2Fciw248 LA - English DB - ProQuest Environmental Science Collection N1 - Date created - 2016-08-02 N1 - Date revised - 2017-01-14 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1093/cid/ciw248 ER - TY - JOUR T1 - Factors Associated with Pregnancy among Incarcerated African American Adolescent Girls AN - 1815697518; PQ0003592262 AB - The purpose of this study was to examine the social and behavioral factors associated with pregnancy history among a sample of African American adolescent girls recruited from a short-term juvenile detention center in order to better understand the needs of this vulnerable population. Data were collected from a sample of 188 detained African American, 13-17-year-old girls in Atlanta, Georgia, who participated in a larger HIV prevention study. An audio computer-assisted self-interviewing survey was completed by participants to obtain information on socioecological factors to include individual, parental/familial, sexual risk, psychosocial, and substance use factors. Among the 188 participants, 25.5 % reported a history of pregnancy. A multivariable logistic regression model showed that girls with a history of pregnancy were more likely to live in a household receiving government aid, use hormonal contraceptives at last sex, participate in sex trading, have casual sex partners, have condomless sex in the past 90 days, and have a history of physical abuse. Girls with no history of pregnancy were more likely to have been incarcerated at least twice and to have previously used alcohol. Detention-based interventions and pregnancy prevention programs for this vulnerable population may benefit by addressing factors related to sexual behavior and development, substance use, individual background, and psychosocial health. JF - Journal of Urban Health AU - Gray, Simone C AU - Holmes, Kristin AU - Bradford, Denise R AD - Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA, simonegray@cdc.gov Y1 - 2016/08// PY - 2016 DA - August 2016 SP - 709 EP - 718 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 93 IS - 4 SN - 1099-3460, 1099-3460 KW - Health & Safety Science Abstracts KW - Alcohol KW - Prisons KW - Historical account KW - Intervention KW - Sexual behavior KW - Substance use KW - Pregnancy KW - prostitution KW - Prevention KW - Human immunodeficiency virus KW - Risk factors KW - Households KW - USA, Georgia, Atlanta KW - Vulnerability KW - Adolescents KW - Ethnic groups KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1815697518?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Urban+Health&rft.atitle=Factors+Associated+with+Pregnancy+among+Incarcerated+African+American+Adolescent+Girls&rft.au=Gray%2C+Simone+C%3BHolmes%2C+Kristin%3BBradford%2C+Denise+R&rft.aulast=Gray&rft.aufirst=Simone&rft.date=2016-08-01&rft.volume=93&rft.issue=4&rft.spage=709&rft.isbn=&rft.btitle=&rft.title=Journal+of+Urban+Health&rft.issn=10993460&rft_id=info:doi/10.1007%2Fs11524-016-0061-x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-08-01 N1 - Number of references - 35 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Historical account; Prisons; Alcohol; Intervention; Substance use; Sexual behavior; Pregnancy; prostitution; Prevention; Households; Risk factors; Vulnerability; Ethnic groups; Adolescents; Human immunodeficiency virus; USA, Georgia, Atlanta DO - http://dx.doi.org/10.1007/s11524-016-0061-x ER - TY - JOUR T1 - Effectiveness of Residential Acaricides to Prevent Lyme and Other Tick-borne Diseases in Humans AN - 1808675671; PQ0003462394 AB - Background. In the northeastern United States, tick-borne diseases are a major public health concern. In controlled studies, a single springtime application of acaricide has been shown to kill 68%-100% of ticks. Although public health authorities recommend use of acaricides to control tick populations in yards, the effectiveness of these pesticides to prevent tick bites or human tick-borne diseases is unknown. Methods. We conducted a 2-year, randomized, double-blinded, placebo-controlled trial among 2727 households in 3 northeastern states. Households received a single springtime barrier application of bifenthrin or water according to recommended practices. Tick drags were conducted 3-4 weeks after treatment on 10% of properties. Information on human-tick encounters and tick-borne diseases was collected through monthly surveys; reports of illness were validated by medical record review. Results. Although the abundance of questing ticks was significantly lower (63%) on acaricide-treated properties, there was no difference between treatment groups in human-tick encounters, self-reported tick-borne diseases, or medical-record-validated tick-borne diseases. Conclusions. Used as recommended, acaricide barrier sprays do not significantly reduce the household risk of tick exposure or incidence of tick-borne disease. Measures for preventing tick-borne diseases should be evaluated against human outcomes to confirm effectiveness. JF - Journal of Infectious Diseases AU - Hinckley, Alison F AU - Meek, James I AU - Ray, Julie A E AU - Niesobecki, Sara A AU - Connally, Neeta P AU - Feldman, Katherine A AU - Jones, Erin H AU - Backenson, P Bryon AU - White, Jennifer L AU - Lukacik, Gary AU - Kay, Ashley B AU - Miranda, Wilson P AU - Mead, Paul S AD - Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado, ahinckley@cdc.gov Y1 - 2016/07/15/ PY - 2016 DA - 2016 Jul 15 SP - 182 EP - 188 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 214 IS - 2 SN - 0022-1899, 0022-1899 KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts; Health & Safety Science Abstracts KW - Lyme disease KW - tick-borne diseases KW - ticks KW - prevention KW - pesticide acaricide KW - humans KW - Bites KW - medical records KW - Ixodidae KW - Sprays KW - Abundance KW - Clinical trials KW - Public health KW - USA KW - Infectious diseases KW - Households KW - Reviews KW - Pesticides KW - Borrelia KW - Acaricides KW - H 5000:Pesticides KW - J 02400:Human Diseases KW - F 06910:Microorganisms & Parasites UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808675671?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Effectiveness+of+Residential+Acaricides+to+Prevent+Lyme+and+Other+Tick-borne+Diseases+in+Humans&rft.au=Hinckley%2C+Alison+F%3BMeek%2C+James+I%3BRay%2C+Julie+A+E%3BNiesobecki%2C+Sara+A%3BConnally%2C+Neeta+P%3BFeldman%2C+Katherine+A%3BJones%2C+Erin+H%3BBackenson%2C+P+Bryon%3BWhite%2C+Jennifer+L%3BLukacik%2C+Gary%3BKay%2C+Ashley+B%3BMiranda%2C+Wilson+P%3BMead%2C+Paul+S&rft.aulast=Hinckley&rft.aufirst=Alison&rft.date=2016-07-15&rft.volume=214&rft.issue=2&rft.spage=182&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiv775 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - medical records; Bites; Reviews; Abundance; Pesticides; tick-borne diseases; Acaricides; Public health; Infectious diseases; Households; Sprays; Clinical trials; Ixodidae; Borrelia; USA DO - http://dx.doi.org/10.1093/infdis/jiv775 ER - TY - JOUR T1 - Predictors of micronutrient powder intake adherence in a pilot programme in Nepal AN - 1846409908; PQ0003835501 AB - Poor adherence to recommended intake protocols is common and a top challenge for micronutrient powder (MNP) programmes globally. Identifying modifiable predictors of intake adherence could inform the design and implementation of MNP projects. We assessed high MNP intake adherence among children who had received MNP greater than or equal to 2 months ago and consumed greater than or equal to 1 sachet (n 771). High MNP intake adherence was defined as maternal report of child intake greater than or equal to 45 sachets. We used logistic regression to assess demographic, intervention components and perception-of-use factors associated with high MNP intake. Four districts of Nepal piloting an integrated infant and young child feeding and MNP project. Children aged 6-23 months were eligible to receive sixty MNP sachets every 6 months with suggested intake of one sachet daily for 60 d. Cross-sectional surveys representative of children aged 6-23 months were conducted. Receiving a reminder card was associated with increased odds for high intake (OR=2.18, 95 % CI 1.14, 4.18); exposure to other programme components was not associated with high intake. Mothers perceiving greater than or equal to 1 positive effects in their child after MNP use was also associated with high intake (OR=6.55, 95 % CI 4.29, 10.01). Perceiving negative affects was not associated; however, the child not liking the food with MNP was associated with lower odds of high intake (OR=0.12, 95 % CI 0.08, 0.20). Behaviour change intervention strategies tailored to address these modifiable predictors could potentially increase MNP intake adherence. JF - Public Health Nutrition AU - Mirkovic, Kelsey R AU - Perrine, Cria G AU - Subedi, Giri Raj AU - Mebrahtu, Saba AU - Dahal, Pradiumna AU - Staatz, Colleen AU - Jefferds, Maria Elena D AD - US Centers for Disease Control and Prevention, 4770 Buford Hwy NE, Mailstop F-77, Atlanta, GA 30341, USA, mjefferds@cdc.gov Y1 - 2016/07// PY - 2016 DA - July 2016 SP - 1768 EP - 1776 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 19 IS - 10 SN - 1368-9800, 1368-9800 KW - Health & Safety Science Abstracts; Calcium & Calcified Tissue Abstracts KW - Powder KW - Emotions KW - Feeding KW - Food KW - Intervention KW - Children KW - Nepal KW - Public health KW - Demography KW - Reminder KW - Micronutrients KW - Infants KW - H 12000:Epidemiology and Public Health KW - T 2020:Nutrition and Metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1846409908?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Public+Health+Nutrition&rft.atitle=Predictors+of+micronutrient+powder+intake+adherence+in+a+pilot+programme+in+Nepal&rft.au=Mirkovic%2C+Kelsey+R%3BPerrine%2C+Cria+G%3BSubedi%2C+Giri+Raj%3BMebrahtu%2C+Saba%3BDahal%2C+Pradiumna%3BStaatz%2C+Colleen%3BJefferds%2C+Maria+Elena+D&rft.aulast=Mirkovic&rft.aufirst=Kelsey&rft.date=2016-07-01&rft.volume=19&rft.issue=10&rft.spage=1768&rft.isbn=&rft.btitle=&rft.title=Public+Health+Nutrition&rft.issn=13689800&rft_id=info:doi/10.1017%2FS1368980015003572 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-12-01 N1 - Number of references - 14 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Demography; Feeding; Emotions; Powder; Food; Reminder; Micronutrients; Children; Infants; Public health; Intervention; Nepal DO - http://dx.doi.org/10.1017/S1368980015003572 ER - TY - JOUR T1 - ENDEMIC ORTHOPOXVIRUS CIRCULATING IN PROCYONIDS IN MEXICO AN - 1837302444; PQ0003752796 AB - Limited serosurveillance studies suggested that orthopoxviruses (OPXV) are widespread in the US (e.g., Raccoonpox virus, Skunkpox virus, Volepox virus) and Brazil (Vaccinia virus); however, their animal reservoir(s) remain unconfirmed. Mexican mammal diversity includes several species related to those in which evidence for OPXV infections has been found (Oryzomys, Peromyscus, Microtus, and Procyonidae). The presence of these groups of mammals in Mexico and the evidence of their possible involvement in the maintenance of OPXV in nature suggest the same or similar OPXV are circulating in Mexico. We tested 201 sera from 129 procyonids via modified enzyme-linked immunosorbent assay (ELISA) and Western blot (WB) to estimate OPXV antibody prevalence in these animals. We detected a prevalence of 16.67% in Nasua narica(white-nosed coati), 35% in Procyon lotor(raccoon), and 30.4% in Bassariscus astutus(ring-tailed cat) when tested by either ELISA or WB. Western blot results presented protein bands consistent with the size of some OPXV immunodominant bands (14, 18, 32, 36, and 62 kDa). These results support the hypothesis that OPXV circulate in at least three genera of Procyonidae in Central and Southeast Mexico. JF - Journal of Wildlife Diseases AU - Gallardo-Romero, Nadia F AU - Arechiga-Ceballos, Nidia AU - Emerson, Ginny L AU - Martinez-Martinez, Flor O AU - Doty, Jeffrey B AU - Nakazawa, Yoshinori J AU - Rendon-Franco, Emilio AU - Munoz-Garcia, Claudia I AU - Villanueva-Garcia, Claudia AU - Ramirez-Cid, Citlali AU - Gama-Campillo, Lilia M AU - Gual-Sill, Fernando AU - Aguilar-Setien, Alvaro AU - Carroll, Darin S AD - Poxvirus and Rabies Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd., Atlanta, Georgia 30333, USA, hfa5@cdc.gov Y1 - 2016/07// PY - 2016 DA - July 2016 SP - 609 EP - 615 PB - Allen Press, Inc., 810 East Tenth St. Lawrence KS 66044 United States VL - 52 IS - 3 SN - 0090-3558, 0090-3558 KW - Virology & AIDS Abstracts; Ecology Abstracts KW - Antibody prevalence KW - Orthopoxvirus KW - procyonids KW - serosurvey KW - Western blotting KW - Enzyme-linked immunosorbent assay KW - Procyon KW - Microtus KW - Infection KW - Oryzomys KW - Nasua KW - Procyonidae KW - Antibodies KW - Vaccinia virus KW - Bassariscus KW - Poxviridae KW - Peromyscus KW - V 22410:Animal Diseases KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1837302444?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Wildlife+Diseases&rft.atitle=ENDEMIC+ORTHOPOXVIRUS+CIRCULATING+IN+PROCYONIDS+IN+MEXICO&rft.au=Gallardo-Romero%2C+Nadia+F%3BArechiga-Ceballos%2C+Nidia%3BEmerson%2C+Ginny+L%3BMartinez-Martinez%2C+Flor+O%3BDoty%2C+Jeffrey+B%3BNakazawa%2C+Yoshinori+J%3BRendon-Franco%2C+Emilio%3BMunoz-Garcia%2C+Claudia+I%3BVillanueva-Garcia%2C+Claudia%3BRamirez-Cid%2C+Citlali%3BGama-Campillo%2C+Lilia+M%3BGual-Sill%2C+Fernando%3BAguilar-Setien%2C+Alvaro%3BCarroll%2C+Darin+S&rft.aulast=Gallardo-Romero&rft.aufirst=Nadia&rft.date=2016-07-01&rft.volume=52&rft.issue=3&rft.spage=609&rft.isbn=&rft.btitle=&rft.title=Journal+of+Wildlife+Diseases&rft.issn=00903558&rft_id=info:doi/10.7589%2F2015-10-291 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-11-01 N1 - Last updated - 2016-11-09 N1 - SubjectsTermNotLitGenreText - Western blotting; Antibodies; Enzyme-linked immunosorbent assay; Infection; Nasua; Procyonidae; Vaccinia virus; Procyon; Microtus; Bassariscus; Poxviridae; Peromyscus; Oryzomys DO - http://dx.doi.org/10.7589/2015-10-291 ER - TY - JOUR T1 - What Happens When "Germs Don't Get Killed and They Attack Again and Again": Perceptions of Antimicrobial Resistance in the Context of Diarrheal Disease Treatment Among Laypersons and Health-Care Providers in Karachi, Pakistan AN - 1808641697; PQ0003465329 AB - In south Asia, where diarrhea is common and antibiotics are accessible without prescription, antimicrobial resistance is an emerging and serious problem. However, beliefs and behaviors related to antimicrobial resistance are poorly understood. We explored laypersons' and health-care providers' (HCP) awareness and perceptions of antimicrobial resistance in the context of treatment of adult diarrheal disease in Karachi, Pakistan. In-depth, open-ended interviews were conducted with 40 laypersons and 45 HCPs in a lower-middle-class urban neighborhood. Interviews conducted in Urdu were audiotaped, transcribed, translated, and coded using applied thematic analysis. Slightly over half of laypersons and two-thirds of HCPs were aware that antimicrobial medication could lose effectiveness, but misperceptions were common. Laypersons and HCPs often believed that "the body becomes immune" or "bacteria attack more strongly" if medications are taken "improperly." Another prevalent theme was that causes and effects of antimicrobial resistance are limited to the individual taking the antimicrobial medication and to the specific diarrheal episode. Participants often attributed antimicrobial resistance to patient behaviors; HCP behavior was rarely discussed. Less than half of the HCPs were aware of treatment guidelines. To combat antimicrobial resistance in urban Pakistan, a health systems strategy and community-supported outreach campaigns on appropriate antimicrobial use are needed. JF - American Journal of Tropical Medicine and Hygiene AU - Joseph, Heather A AU - Agboatwalla, Mubina AU - Hurd, Jacqueline AU - Jacobs-Slifka, Kara AU - Pitz, Adam AU - Bowen, Anna AD - Division of Global Migration and Quarantine, Centers for Disease Control and Prevention, Atlanta, Georgia, hjoseph1@cdc.gov Y1 - 2016/07// PY - 2016 DA - July 2016 SP - 221 EP - 228 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 95 IS - 1 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Diarrhea KW - Community involvement KW - Drug resistance KW - Guidelines KW - Disease control KW - Therapy KW - Antibiotics KW - Disease resistance KW - Antimicrobial agents KW - Perception KW - Pakistan, Sindh, Karachi KW - Asia KW - Hygiene KW - Drugs KW - Antibiotic resistance KW - A 01340:Antibiotics & Antimicrobials KW - Q1 08625:Non-edible products KW - K 03400:Human Diseases KW - Q5 08524:Public health, medicines, dangerous organisms KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808641697?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=What+Happens+When+%22Germs+Don%27t+Get+Killed+and+They+Attack+Again+and+Again%22%3A+Perceptions+of+Antimicrobial+Resistance+in+the+Context+of+Diarrheal+Disease+Treatment+Among+Laypersons+and+Health-Care+Providers+in+Karachi%2C+Pakistan&rft.au=Joseph%2C+Heather+A%3BAgboatwalla%2C+Mubina%3BHurd%2C+Jacqueline%3BJacobs-Slifka%2C+Kara%3BPitz%2C+Adam%3BBowen%2C+Anna&rft.aulast=Joseph&rft.aufirst=Heather&rft.date=2016-07-01&rft.volume=95&rft.issue=1&rft.spage=221&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.15-0661 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Therapy; Disease control; Hygiene; Diarrhea; Perception; Drug resistance; Antibiotics; Antimicrobial agents; Community involvement; Guidelines; Disease resistance; Drugs; Antibiotic resistance; Pakistan, Sindh, Karachi; Asia DO - http://dx.doi.org/10.4269/ajtmh.15-0661 ER - TY - JOUR T1 - Responding to changes in HIV policy: Updating and enhancing the Families Matter! curriculum AN - 1808709072; PQ0003194349 AB - Objectives: The past decade has seen changes in US HIV policy in sub-Saharan Africa in response to a new Administration and far-reaching technical, scientific and programmatic developments. These include dramatically increased access to life-saving anti-retroviral therapy (ART) and related services, the roll-out of voluntary medical male circumcision and growing sensitivity to gender-based violence, including child sexual abuse, and to its role in increasing vulnerability to HIV. The Families Matter! Program (FMP) is an intervention for parents and caregivers of 9- to 12-year-olds that promotes effective parent-child communication about sexuality and sexual risk reduction. FMP was adapted from a US evidence-based intervention in 2003-2004 and is now implemented in eight African countries. In 2012-2013, the FMP curriculum was updated and enhanced to respond to new US Government priorities. Methods: Enhancements to the curriculum drew on the results of Violence Against Children surveys, on a review of existing literature, on feedback from the field on the existing curriculum and on stories written by young people across Africa for scriptwriting competitions. Results: We updated FMP with scientific content and stronger linkages to services. We also intensified our focus on structural determinants of risk. This contextualisation of sexual risk-taking within structural constraints led us to place greater emphasis on gendered vulnerability and the diverse pressures children face and to intensify our situation-based pedagogical approach, drawing on the authentic youth-authored narratives. Conclusion: We describe these changes as an illustration of and source of insight into much-needed programmatic adaptation in response to evolving HIV policy. JF - Health Education Journal AU - Miller, Kim S AU - Winskell, Kate AU - Berrier, Faith L AD - a .Division of Global HIV/AIDS, Centers for Disease Control and Prevention, Atlanta, GA, USA, FBerrier@cdc.gov Y1 - 2016/06// PY - 2016 DA - June 2016 SP - 409 EP - 420 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU United Kingdom VL - 75 IS - 4 SN - 0017-8969, 0017-8969 KW - Health & Safety Science Abstracts KW - Child sexual abuse KW - gender-based violence KW - parenting KW - policy KW - preadolescence KW - Sensitivity KW - Intervention KW - Risk reduction KW - Children KW - Sexual behavior KW - Violence KW - Education KW - Adaptability KW - Communications KW - Human immunodeficiency virus KW - Reviews KW - Child abuse KW - Africa KW - Vulnerability KW - Competition KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808709072?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+Education+Journal&rft.atitle=Responding+to+changes+in+HIV+policy%3A+Updating+and+enhancing+the+Families+Matter%21+curriculum&rft.au=Miller%2C+Kim+S%3BWinskell%2C+Kate%3BBerrier%2C+Faith+L&rft.aulast=Miller&rft.aufirst=Kim&rft.date=2016-06-01&rft.volume=75&rft.issue=4&rft.spage=409&rft.isbn=&rft.btitle=&rft.title=Health+Education+Journal&rft.issn=00178969&rft_id=info:doi/10.1177%2F0017896915595530 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Number of references - 28 N1 - Last updated - 2016-08-17 N1 - SubjectsTermNotLitGenreText - Sensitivity; Intervention; Risk reduction; Children; Violence; Sexual behavior; Adaptability; Education; Communications; Human immunodeficiency virus; Reviews; Child abuse; Vulnerability; Competition; Africa DO - http://dx.doi.org/10.1177/0017896915595530 ER - TY - JOUR T1 - Hepatitis B Vaccination Coverage and Prevalence of Hepatitis B Surface Antigen Among Children in French Polynesia, 2014 AN - 1808635208; PQ0003290537 AB - French Polynesia is considered to be moderately endemic for chronic hepatitis B virus infection, with an estimated 3% of the population having hepatitis B surface antigen (HBsAg). From 1990 to 1992, a 3-dose hepatitis B vaccination series was introduced into the routine infant immunization schedule in French Polynesia, including a birth dose (BD). In 2014, a nationally representative 2-stage cluster survey was undertaken to evaluate the impact of the vaccination program on HBsAg prevalence among school children (~6 years of age) in Cours Preparatoire (CP). Documented vaccination data were reviewed for all eligible children; children with consent were tested for HBsAg with a rapid point-of-care test. In total, 1,660 students were identified; 1,567 (94%) had vaccination data for review and 1,196 (72%) participated in the serosurvey. Three-dose vaccination coverage was 98%, while timely BD coverage, defined as a dose administered within 24 hours of life, was 89%. Receipt of the second and third doses was often delayed, with 75% and 55% receiving a second and third dose within 1 month of the recommended age, respectively. No children tested positive for HBsAg. French Polynesia's vaccination program has achieved high coverage and an HBsAg seroprevalence of 0% (0-0.5%) among CP school children, but timeliness of vaccination could be improved. JF - American Journal of Tropical Medicine and Hygiene AU - Patel, Minal K AU - Le Calvez, Evelyne AU - Wannemuehler, Kathleen AU - Segalin, Jean-Marc AD - Global Immunization Division, Centers for Disease Control and Prevention, Atlanta, Georgia, hgo9@cdc.gov Y1 - 2016/06// PY - 2016 DA - June 2016 SP - 1370 EP - 1375 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 94 IS - 6 SN - 0002-9637, 0002-9637 KW - Virology & AIDS Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Age KW - Viruses KW - Parturition KW - Hepatitis B surface antigen KW - Infection KW - Endemic species KW - Antigens KW - Biological surveys KW - Data processing KW - Hepatitis B virus KW - ISE, Pacific, French Polynesia KW - Children KW - Vaccination KW - Education establishments KW - Immunization KW - Birth KW - Reviews KW - Chronic infection KW - Vaccines KW - Hygiene KW - Infants KW - K 03400:Human Diseases KW - Q1 08604:Stock assessment and management KW - Q5 08524:Public health, medicines, dangerous organisms KW - H 0500:General KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808635208?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Hepatitis+B+Vaccination+Coverage+and+Prevalence+of+Hepatitis+B+Surface+Antigen+Among+Children+in+French+Polynesia%2C+2014&rft.au=Patel%2C+Minal+K%3BLe+Calvez%2C+Evelyne%3BWannemuehler%2C+Kathleen%3BSegalin%2C+Jean-Marc&rft.aulast=Patel&rft.aufirst=Minal&rft.date=2016-06-01&rft.volume=94&rft.issue=6&rft.spage=1370&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.15-0903 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Biological surveys; Endemic species; Antigens; Parturition; Hygiene; Education establishments; Vaccination; Immunization; Birth; Age; Data processing; Reviews; Chronic infection; Hepatitis B surface antigen; Children; Infants; Viruses; Vaccines; Infection; Hepatitis B virus; ISE, Pacific, French Polynesia DO - http://dx.doi.org/10.4269/ajtmh.15-0903 ER - TY - JOUR T1 - The contribution of subsidized food commodities to total energy intake among US adults AN - 1787985036; PQ0002987245 AB - The contribution of subsidized food commodities to total food consumption is unknown. We estimated the proportion of individual energy intake from food commodities receiving the largest subsidies from 1995 to 2010 (corn, soyabeans, wheat, rice, sorghum, dairy and livestock). Integrating information from three federal databases (MyPyramid Equivalents, Food Intakes Converted to Retail Commodities, and What We Eat in America) with data from the 2001-2006 National Health and Nutrition Examination Surveys, we computed a Subsidy Score representing the percentage of total energy intake from subsidized commodities. We examined the score's distribution and the probability of having a 'high' ( greater than or equal to 70th percentile) v. 'low' ( less than or equal to 30th percentile) score, across the population and subgroups, using multivariate logistic regression. Community-dwelling adults in the USA. Participants (n 11 811) aged 18-64 years. Median Subsidy Score was 56.7 % (interquartile range 47.2-65.4 %). Younger, less educated, poorer, and Mexican Americans had higher scores. After controlling for covariates, age, education and income remained independently associated with the score: compared with individuals aged 55-64 years, individuals aged 18-24 years had a 50 % higher probability of having a high score (P<0.0001). Individuals reporting less than high-school education had 21 % higher probability of having a high score than individuals reporting college completion or higher (P=0.003); individuals in the lowest tertile of income had an 11 % higher probability of having a high score compared with individuals in the highest tertile (P=0.02). Over 50 % of energy in US diets is derived from federally subsidized commodities. JF - Public Health Nutrition AU - Siegel, Karen R AU - McKeever Bullard, Kai AU - Ali, Mohammed K AU - Stein, Aryeh D AU - Kahn, Henry S AU - Mehta, Neil K AU - Webb Girard, Amy AU - Narayan, K M AU - Imperatore, Giuseppina AD - Division of Diabetes Translation, Centers for Disease Control and Prevention, 4770 Buford Highway, Atlanta, GA 30341, USA, yuo0@cdc.gov Y1 - 2016/06// PY - 2016 DA - June 2016 SP - 1348 EP - 1357 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 19 IS - 8 SN - 1368-9800, 1368-9800 KW - Health & Safety Science Abstracts KW - Diets KW - Age KW - Nutrition KW - Income KW - Livestock KW - Triticum aestivum KW - USA KW - Education KW - Dairies KW - Energy KW - Corn KW - Subsidies KW - Wheat KW - Ethnic groups KW - Sorghum KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1787985036?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Public+Health+Nutrition&rft.atitle=The+contribution+of+subsidized+food+commodities+to+total+energy+intake+among+US+adults&rft.au=Siegel%2C+Karen+R%3BMcKeever+Bullard%2C+Kai%3BAli%2C+Mohammed+K%3BStein%2C+Aryeh+D%3BKahn%2C+Henry+S%3BMehta%2C+Neil+K%3BWebb+Girard%2C+Amy%3BNarayan%2C+K+M%3BImperatore%2C+Giuseppina&rft.aulast=Siegel&rft.aufirst=Karen&rft.date=2016-06-01&rft.volume=19&rft.issue=8&rft.spage=1348&rft.isbn=&rft.btitle=&rft.title=Public+Health+Nutrition&rft.issn=13689800&rft_id=info:doi/10.1017%2FS1368980015002414 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-05-01 N1 - Number of references - 33 N1 - Last updated - 2016-07-07 N1 - SubjectsTermNotLitGenreText - Diets; Age; Dairies; Education; Energy; Corn; Subsidies; Wheat; Nutrition; Ethnic groups; Livestock; Income; Triticum aestivum; Sorghum; USA DO - http://dx.doi.org/10.1017/S1368980015002414 ER - TY - JOUR T1 - Integrating Water Treatment into Antenatal Care: Impact on Use of Maternal Health Services and Household Water Treatment by Mothers-Rural Uganda, 2013 AN - 1790950278; PQ0003120382 AB - To increase maternal health service use and household water treatment (HWT), free water treatment kits were provided at first antenatal care (ANC) visits and free water treatment sachet refills were provided at follow-up ANC visits, delivery, and postnatal visits in 46 health facilities in rural Uganda. We evaluated the impact by surveying 226 women in the initiative (intervention group) and 207 women who received ANC before the initiative began (comparison group). There was no differences in the percentages of intervention and comparison group women with > or = 4 ANC visits; however, a higher percentage of intervention group women reported treating their drinking water (31.7% versus 19.7%, P= 0.01), and had free chlorine residual in stored water (13.5% versus 3.4%, P= 0.02) than comparison group women. The intervention did not appear to motivate increased maternal health service use, but demonstrated improvements in HWT. JF - American Journal of Tropical Medicine and Hygiene AU - Matanock, Almea AU - Anderson, Tara AU - Ayers, Tracy AU - Likicho, Lilian AU - Wamimbi, Richard AU - Lu, Xin AU - Emeetai, Thomas AU - Kakande, Celia AU - Mutabazi, Miriam AU - Quick, Robert AD - Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, xdf2@cdc.gov Y1 - 2016/05// PY - 2016 DA - May 2016 SP - 1150 EP - 1156 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 94 IS - 5 SN - 0002-9637, 0002-9637 KW - ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Intervention KW - Chlorine KW - Uganda KW - Drinking Water KW - Water treatment KW - Surveying KW - Households KW - Chlorination KW - Drinking water KW - Hygiene KW - Rural areas KW - Q5 08503:Characteristics, behavior and fate KW - H 3000:Environment and Ecology KW - K 03400:Human Diseases KW - Q1 08604:Stock assessment and management UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1790950278?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Integrating+Water+Treatment+into+Antenatal+Care%3A+Impact+on+Use+of+Maternal+Health+Services+and+Household+Water+Treatment+by+Mothers-Rural+Uganda%2C+2013&rft.au=Matanock%2C+Almea%3BAnderson%2C+Tara%3BAyers%2C+Tracy%3BLikicho%2C+Lilian%3BWamimbi%2C+Richard%3BLu%2C+Xin%3BEmeetai%2C+Thomas%3BKakande%2C+Celia%3BMutabazi%2C+Miriam%3BQuick%2C+Robert&rft.aulast=Matanock&rft.aufirst=Almea&rft.date=2016-05-01&rft.volume=94&rft.issue=5&rft.spage=1150&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.15-0356 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-05-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Drinking Water; Surveying; Water treatment; Hygiene; Chlorine; Drinking water; Households; Intervention; Chlorination; Rural areas; Uganda DO - http://dx.doi.org/10.4269/ajtmh.15-0356 ER - TY - JOUR T1 - Serological Evidence of Infection with Endemic Human Pathogens Among Free-Ranging Old World Monkeys in Puerto Rico AN - 1790946937; PQ0003120374 AB - Serum specimens from free-ranging but nonnative patas monkeys (Erythrocebus patas) and rhesus macaques (Macaca mulatta) in southwestern Puerto Rico (PR) were tested for antibodies to infection with dengue viruses (DENVs), West Nile virus (WNV), Leptospira species, and Burkholderia pseudomallei by microneutralization, plaque reduction neutralization, microscopic agglutination, and indirect hemagglutination, respectively. Of 23 animals (21 E. patas and two M. mulatta) tested, all had evidence of prior DENV infection, and of 17 animals tested for WNV, nine (53%) had evidence of prior infection. Of 24 (22 E. patas, two M. mulatta) tested for Leptospira spp., 10 (42%) had evidence of prior exposure, and one patas monkey had antibodies against B. pseudomallei. The acquisition of pathogens endemic among humans in PR by resident nonhuman primates merits further study to define modes of acquisition. JF - American Journal of Tropical Medicine and Hygiene AU - Hemme, Ryan R AU - Lopez-Ortiz, Ricardo AU - Garcia, Brenda Rivera AU - Sharp, Tyler M AU - Galloway, Renee L AU - Elrod, Mindy G AU - Hunsperger, Elizabeth A AD - Dengue Branch, Centers for Disease Control and Prevention, San Juan, Puerto Rico, rhemme@cdc.gov Y1 - 2016/05// PY - 2016 DA - May 2016 SP - 1095 EP - 1099 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 94 IS - 5 SN - 0002-9637, 0002-9637 KW - ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Human diseases KW - Viruses KW - Leptospira KW - Infection KW - Public health KW - Agglutination KW - Endemic species KW - Dengue KW - Macaca mulatta KW - Plaques KW - Neutralization KW - Burkholderia pseudomallei KW - Pathogens KW - Primates KW - Indirect hemagglutination KW - Antibodies KW - ASW, Caribbean Sea, Greater Antilles, Puerto Rico KW - Serum KW - Erythrocebus patas KW - Hygiene KW - West Nile virus KW - K 03410:Animal Diseases KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1790946937?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Serological+Evidence+of+Infection+with+Endemic+Human+Pathogens+Among+Free-Ranging+Old+World+Monkeys+in+Puerto+Rico&rft.au=Hemme%2C+Ryan+R%3BLopez-Ortiz%2C+Ricardo%3BGarcia%2C+Brenda+Rivera%3BSharp%2C+Tyler+M%3BGalloway%2C+Renee+L%3BElrod%2C+Mindy+G%3BHunsperger%2C+Elizabeth+A&rft.aulast=Hemme&rft.aufirst=Ryan&rft.date=2016-05-01&rft.volume=94&rft.issue=5&rft.spage=1095&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.15-0262 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-05-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Human diseases; Endemic species; Antibodies; Serum; Viruses; Pathogens; Hygiene; Public health; Agglutination; Dengue; Plaques; Infection; Indirect hemagglutination; Primates; Neutralization; Burkholderia pseudomallei; Leptospira; Macaca mulatta; Erythrocebus patas; West Nile virus; ASW, Caribbean Sea, Greater Antilles, Puerto Rico DO - http://dx.doi.org/10.4269/ajtmh.15-0262 ER - TY - JOUR T1 - Identifying Best Practices for Increasing Linkage to, Retention, and Re-engagement in HIV Medical Care: Findings from a Systematic Review, 1996-2014 AN - 1787983552; PQ0002973179 AB - A systematic review was conducted to identify best practices for increasing linkage, retention and re-engagement in HIV care (LRC) for persons living with HIV (PLWH). Our search strategy consisted of automated searches of electronic databases and hand searches of journals, reference lists and listservs. We developed two sets of criteria: evidence-based to identify evidence-based interventions (EBIs) tested with a comparison group and evidence-informed to identify evidence-informed interventions (EIs) tested with a one-group design. Eligible interventions included being published between 1996 and 2014, U.S.-based studies with a comparison or one-group designs with pre-post data, international randomized controlled trials, and having objective measures of LRC-relevant outcomes. We identified 10 best practices: 5 EBIs and 5 EIs. None focused on re-engagement. Providers and prevention planners can use the review findings to identify best practices suitable for their clinics, agencies, or communities to increase engagement in care for PLWH, ultimately leading to viral suppression.Original Abstract: Una revision sistematica se realizo para identificar las mejores practicas para aumentar la vinculacion, la permanencia y el regreso hasta atencion medica del VIH (VPR) para las personas que viven con el VIH (PVVS). La estrategia de busqueda consistio en busquedas automatizadas de bases de datos electronicas y busquedas manuales en revistas, listas de referencias y listas de correo electronico. Hemos desarrollado dos juegos de criterios: "basadas en evidencias" para identificar las intervenciones basadas en la evidencia y probadas con un grupo de comparacion (IBEs), y "informadas por evidencias" para identificar las intervenciones informadas por evidencias y probadas con un diseno empleando un solo grupo (IIEs). Intervenciones elegibles incluyeron siendo publicados entre 1996 y 2014, estudiados en los Estados Unidos con un grupo de comparacion o uno grupo con datos pre-post, ensayos internacionales controlados aleatorios, y que tienen medidas objetivas de resultados VPR-relevantes. Se identificaron 10 mejores practicas: 5 IBEs y 5 IIEs. Ninguno se centro en un regreso hasta atencion medica. Los proveedores y los planificadores de prevencion pueden utilizar los resultados de la revision para identificar las mejores practicas adecuadas para sus clinicas, agencias, o comunidades para aumentar la participacion en la atencion medica para las PVVS, en ultima instancia conduciendo a la supresion viral. JF - AIDS and Behavior AU - Higa, Darrel H AU - Crepaz, Nicole AU - Mullins, Mary M AD - Prevention Research Branch, Division of HIV/AIDS, Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Mailstop E-37, Atlanta, GA, 30329, USA, dhiga@cdc.gov Y1 - 2016/05// PY - 2016 DA - May 2016 SP - 951 EP - 966 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 20 IS - 5 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Acquired immune deficiency syndrome KW - Data processing KW - Best practices KW - Intervention KW - Hand KW - Clinical trials KW - Databases KW - Prevention KW - Behavior KW - Human immunodeficiency virus KW - Reviews KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1787983552?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Identifying+Best+Practices+for+Increasing+Linkage+to%2C+Retention%2C+and+Re-engagement+in+HIV+Medical+Care%3A+Findings+from+a+Systematic+Review%2C+1996-2014&rft.au=Higa%2C+Darrel+H%3BCrepaz%2C+Nicole%3BMullins%2C+Mary+M&rft.aulast=Higa&rft.aufirst=Darrel&rft.date=2016-05-01&rft.volume=20&rft.issue=5&rft.spage=951&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-015-1204-x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-05-01 N1 - Number of references - 50 N1 - Last updated - 2016-07-07 N1 - SubjectsTermNotLitGenreText - Databases; Data processing; Reviews; Hand; Prevention; Acquired immune deficiency syndrome; Behavior; Human immunodeficiency virus; Best practices; Intervention; Clinical trials DO - http://dx.doi.org/10.1007/s10461-015-1204-x ER - TY - JOUR T1 - Late Diagnosis of HIV Infection in Metropolitan Areas of the United States and Puerto Rico AN - 1787982803; PQ0002973186 AB - The majority of persons infected with HIV live in large metropolitan areas and many such areas have implemented intensified HIV testing programs. A national indicator of HIV testing outcomes is late diagnosis of HIV infection (stage 3, AIDS). Based on National HIV Surveillance System data, 23.3 % of persons with HIV diagnosed in 2012 had a late diagnosis in large MSAs, 26.3 % in smaller MSAs, and 29.6 % in non-metropolitan areas. In the 105 large MSAs, the percentage diagnosed late ranged from 13.2 to 47.4 %. During 2003-2012, the percentage diagnosed late decreased in large MSAs (32.2-23.3 %), with significant decreases in 41 of 105 MSAs overall and among men who have sex with men. Sustained testing efforts may help to continue the decreasing trend in late-stage HIV diagnosis and provide opportunities for early care and treatment and potential reduction in HIV transmission.Original Abstract: La mayoria de las personas infectadas con el VIH viven en grandes areas metropolitanas y muchas de esas areas han implementado programas intensivos de pruebas de VIH. Un indicador nacional del resultado de las actividades de pruebas de VIH es el diagnostico tardio de la infeccion por VIH (clasificacion 3, SIDA). Basado en datos del Sistema Nacional de Vigilancia de VIH, el 23.3 % de las personas con VIH diagnosticadas en 2012 en areas estadisticas metropolitanas (MSA por sus siglas en ingles) grandes, tuvo un diagnostico tardio, el 26.3 % en las MSA mas pequenas, y 29.6 % en las areas no metropolitanas. En las 105 MSA grandes, el porcentaje de diagnosticos tardios oscilo entre 13.2 % y 47.4 %. Del 2003 al 2012, el porcentaje de diagnosticos tardios disminuyo en las MSA grandes (del 32.3 % al 23.3 %), con una disminucion significativa en 41 de las 105 MSA grandes y entre hombres que tienen sexo con hombres. Los esfuerzos continuos en proveer pruebas de VIH pueden ayudar a continuar la tendencia decreciente de diagnosticos tardios del VIH, y proporcionar oportunidades para la atencion y tratamiento oportuno, y la reduccion potencial en la transmision del VIH. JF - AIDS and Behavior AU - Hall, HIrene AU - Tang, Tian AU - Espinoza, Lorena AD - Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road NE, E-47, Atlanta, GA, 30329-4027, USA, ixh1@cdc.gov Y1 - 2016/05// PY - 2016 DA - May 2016 SP - 967 EP - 972 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 20 IS - 5 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Acquired immune deficiency syndrome KW - Data processing KW - Homosexuality KW - Infection KW - Disease transmission KW - USA KW - Behavior KW - ASW, Caribbean Sea, Greater Antilles, Puerto Rico KW - Human immunodeficiency virus KW - Metropolitan areas KW - Sex KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1787982803?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Late+Diagnosis+of+HIV+Infection+in+Metropolitan+Areas+of+the+United+States+and+Puerto+Rico&rft.au=Hall%2C+HIrene%3BTang%2C+Tian%3BEspinoza%2C+Lorena&rft.aulast=Hall&rft.aufirst=HIrene&rft.date=2016-05-01&rft.volume=20&rft.issue=5&rft.spage=967&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-015-1241-5 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-05-01 N1 - Number of references - 26 N1 - Last updated - 2016-07-07 N1 - SubjectsTermNotLitGenreText - Acquired immune deficiency syndrome; Data processing; Infection; Sex; Disease transmission; Behavior; Human immunodeficiency virus; Homosexuality; Metropolitan areas; USA; ASW, Caribbean Sea, Greater Antilles, Puerto Rico DO - http://dx.doi.org/10.1007/s10461-015-1241-5 ER - TY - JOUR T1 - Phylogenetic Analysis of Chikungunya Virus Strains Circulating in the Western Hemisphere AN - 1794502942; PQ0003147759 AB - In December 2013, chikungunya virus (CHIKV) was isolated for the first time in the Western Hemisphere (WH) during an epidemic on the island of St. Martin. Subsequently, the virus has spread to 42 countries or territories in the Caribbean, Central, South, and North America. In this study, we have determined the full genomic sequences of 29 temporally and geographically diverse CHIKV strains from 16 countries of the WH. Phylogenetic analyses revealed minimal evolution among compared emergent CHIKV strains of the New World. JF - American Journal of Tropical Medicine and Hygiene AU - Lanciotti, Robert S AU - Lambert, Amy J AD - Division of Vector-Borne Disease, Centers for Disease Control and Prevention, Fort Collins, Colorado, ahk7@cdc.gov Y1 - 2016/04// PY - 2016 DA - April 2016 SP - 800 EP - 803 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 94 IS - 4 SN - 0002-9637, 0002-9637 KW - Virology & AIDS Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Phylogeny KW - North America KW - Chikungunya virus KW - Epidemics KW - Nucleotide sequence KW - Territory KW - Strains KW - ASW, Caribbean Sea KW - Islands KW - Home range KW - genomics KW - Hygiene KW - Evolution KW - Phylogenetics KW - Q1 08443:Population genetics KW - Q5 08524:Public health, medicines, dangerous organisms KW - H 0500:General KW - V 22310:Genetics, Taxonomy & Structure KW - K 03310:Genetics & Taxonomy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1794502942?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Phylogenetic+Analysis+of+Chikungunya+Virus+Strains+Circulating+in+the+Western+Hemisphere&rft.au=Lanciotti%2C+Robert+S%3BLambert%2C+Amy+J&rft.aulast=Lanciotti&rft.aufirst=Robert&rft.date=2016-04-01&rft.volume=94&rft.issue=4&rft.spage=800&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.15-0375 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-06-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Epidemics; Nucleotide sequence; Home range; Hygiene; Strains; Phylogenetics; Phylogeny; Islands; Territory; genomics; Evolution; Chikungunya virus; North America; ASW, Caribbean Sea DO - http://dx.doi.org/10.4269/ajtmh.15-0375 ER - TY - JOUR T1 - Detection of Onchocerca volvulus in Skin Snips by Microscopy and Real-Time Polymerase Chain Reaction: Implications for Monitoring and Evaluation Activities AN - 1794495685; PQ0003147776 AB - Microscopic evaluation of skin biopsies is the monitoring and evaluation (M and E) method currently used by multiple onchocerciasis elimination programs in Africa. However, as repeated mass drug administration suppresses microfilarial loads, the sensitivity and programmatic utility of skin snip microscopy is expected to decrease. Using a pan-filarial real-time polymerase chain reaction with melt curve analysis (qPCR-MCA), we evaluated 1) the use of a single-step molecular assay for detecting and identifying Onchocerca volvulus microfilariae in residual skin snips and 2) the sensitivity of skin snip microscopy relative to qPCR-MCA. Skin snips were collected and examined with routine microscopy in hyperendemic regions of Uganda and Ethiopia (N = 500 each) and "residual" skin snips (tissue remaining after induced microfilarial emergence) were tested with qPCR-MCA. qPCR-MCA detected Onchocerca DNA in 223 residual snips: 139 of 147 microscopy(+) and 84 among microscopy(-) snips, suggesting overall sensitivity of microscopy was 62.3% (139/223) relative to qPCR-MCA (75.6% in Uganda and 28.6% in Ethiopia). These findings demonstrate the insufficient sensitivity of skin snip microscopy for reliable programmatic monitoring. Molecular tools such as qPCR-MCA can augment sensitivity and provide diagnostic confirmation of skin biopsies and will be useful for evaluation or validation of new onchocerciasis M and E tools. JF - American Journal of Tropical Medicine and Hygiene AU - Thiele, Elizabeth A AU - Cama, Vitaliano A AU - Lakwo, Thomson AU - Mekasha, Sindeaw AU - Abanyie, Francisca AU - Sleshi, Markos AU - Kebede, Amha AU - Cantey, Paul T AD - Parasitic Diseases Branch, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia, vcama@cdc.gov Y1 - 2016/04// PY - 2016 DA - April 2016 SP - 906 EP - 911 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 94 IS - 4 SN - 0002-9637, 0002-9637 KW - ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Onchocerca volvulus KW - Sensitivity KW - Skin KW - onchocerciasis KW - Nucleotide sequence KW - Uganda KW - Biopsy KW - Methodology KW - Ethiopia KW - Microscopy KW - DNA KW - Africa KW - Polymerase chain reaction KW - Hygiene KW - Drugs KW - Q1 08185:Genetics and evolution KW - Q5 08524:Public health, medicines, dangerous organisms KW - H 0500:General KW - K 03310:Genetics & Taxonomy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1794495685?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Detection+of+Onchocerca+volvulus+in+Skin+Snips+by+Microscopy+and+Real-Time+Polymerase+Chain+Reaction%3A+Implications+for+Monitoring+and+Evaluation+Activities&rft.au=Thiele%2C+Elizabeth+A%3BCama%2C+Vitaliano+A%3BLakwo%2C+Thomson%3BMekasha%2C+Sindeaw%3BAbanyie%2C+Francisca%3BSleshi%2C+Markos%3BKebede%2C+Amha%3BCantey%2C+Paul+T&rft.aulast=Thiele&rft.aufirst=Elizabeth&rft.date=2016-04-01&rft.volume=94&rft.issue=4&rft.spage=906&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.15-0695 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-06-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Nucleotide sequence; Microscopy; DNA; Polymerase chain reaction; Hygiene; Drugs; Methodology; onchocerciasis; Skin; Biopsy; Sensitivity; Onchocerca volvulus; Ethiopia; Africa; Uganda DO - http://dx.doi.org/10.4269/ajtmh.15-0695 ER - TY - JOUR T1 - Do State Community Health Worker Laws Align with Best Available Evidence? AN - 1776649407; PQ0002815877 AB - Community health workers (CHWs) are expected to improve patient care and population health while reducing health care costs. Law is a tool states are using to build a supportive infrastructure for the CHW workforce. This study assessed the extent existing state law pertaining to the CHW workforce aligned with best available evidence. We used the previously developed Quality and Impact of Component (QuIC) Evidence Assessment method to identify and prioritize those components that could comprise an evidence-informed CHW policy at the state level. We next assessed the extent codified statutes and regulations in effect as of December 31, 2014 for the 50 states and D.C. included the components identified in the evidence assessment. Fourteen components of an evidence-informed CHW policy were identified; eight had best, three had promising, and three had emerging evidence bases. Codified law in 18 states (35.3 % of 51) pertained to the CHW workforce. Fifteen of these 18 states authorized at least one of the 14 components from the evidence assessment (maximum: nine components, median: 2.5). The most frequently authorized component was a defined scope of practice for CHWs (authorized by eight states) followed by a standard core competency curriculum and inclusion of CHWs in multidisciplinary health care teams (each authorized by six states). States could consider the components presented in this article when developing new or strengthening existing law. JF - Journal of Community Health AU - Barbero, Colleen AU - Gilchrist, Siobhan AU - Chriqui, Jamie F AU - Martin, Molly A AU - Wennerstrom, Ashley AU - VanderVeur, Jennifer AU - Prewitt, Kim AU - Brownstein, JNell AD - Centers for Disease Control and Prevention, 4770 Buford Highway, Northeast Mail Stop F-75, Atlanta, GA, 30341, USA, vrm5@cdc.gov Y1 - 2016/04// PY - 2016 DA - April 2016 SP - 315 EP - 325 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 41 IS - 2 SN - 0094-5145, 0094-5145 KW - Health & Safety Science Abstracts KW - Infrastructure KW - Health care KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1776649407?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Community+Health&rft.atitle=Do+State+Community+Health+Worker+Laws+Align+with+Best+Available+Evidence%3F&rft.au=Barbero%2C+Colleen%3BGilchrist%2C+Siobhan%3BChriqui%2C+Jamie+F%3BMartin%2C+Molly+A%3BWennerstrom%2C+Ashley%3BVanderVeur%2C+Jennifer%3BPrewitt%2C+Kim%3BBrownstein%2C+JNell&rft.aulast=Barbero&rft.aufirst=Colleen&rft.date=2016-04-01&rft.volume=41&rft.issue=2&rft.spage=315&rft.isbn=&rft.btitle=&rft.title=Journal+of+Community+Health&rft.issn=00945145&rft_id=info:doi/10.1007%2Fs10900-015-0098-x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-03-01 N1 - Number of references - 27 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Infrastructure; Health care DO - http://dx.doi.org/10.1007/s10900-015-0098-x ER - TY - JOUR T1 - Cytomegalovirus Infection in Human Immunodeficiency Virus (HIV)-Exposed and HIV-Infected Infants: A Systematic Review AN - 1785236503; PQ0002903384 AB - Cytomegalovirus is highly prevalent worldwide and an important opportunistic pathogen in human immunodeficiency virus (HIV)-infected individuals. The effects of cytomegalovirus infection on HIV-exposed infants are poorly understood. We conducted a systematic review to assess the relationship between cytomegalovirus and HIV infections among HIV-exposed infants. Limited evidence suggests that HIV-induced immunosuppression in the mother increases the rate of congenital cytomegalovirus infection, while maternal antiretroviral therapy may reduce it. Limited information exists on the direction of the relationship between cytomegalovirus and HIV transmission among HIV-exposed infants. Only 2 studies have addressed this temporal sequence of events, and they suggest that cytomegalovirus can lead to subsequent HIV infection in HIV-exposed infants. Most evidence suggests that early cytomegalovirus infection accelerates HIV disease progression in infants. Gaps remain in understanding the role that cytomegalovirus infection plays in HIV-exposed infants. Decreasing cytomegalovirus transmission prenatally and in infancy might further decrease HIV transmission and lead to better health among HIV-exposed infants. JF - Journal of Infectious Diseases AU - Ellington, Sascha R AU - Clarke, Kristie E N AU - Kourtis, Athena P AD - Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia, sellington@cdc.gov Y1 - 2016/03/15/ PY - 2016 DA - 2016 Mar 15 SP - 891 EP - 900 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 213 IS - 6 SN - 0022-1899, 0022-1899 KW - Immunology Abstracts; Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - cytomegalovirus KW - HIV KW - mother-to-child transmission KW - HIV-exposed infant KW - antiretroviral therapy KW - Pathogens KW - Infection KW - Cytomegalovirus KW - Antiretroviral agents KW - Disease transmission KW - Opportunist infection KW - Human cytomegalovirus KW - Infectious diseases KW - Human immunodeficiency virus KW - Reviews KW - Infants KW - Immunosuppression KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - V 22360:AIDS and HIV UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1785236503?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Cytomegalovirus+Infection+in+Human+Immunodeficiency+Virus+%28HIV%29-Exposed+and+HIV-Infected+Infants%3A+A+Systematic+Review&rft.au=Ellington%2C+Sascha+R%3BClarke%2C+Kristie+E+N%3BKourtis%2C+Athena+P&rft.aulast=Ellington&rft.aufirst=Sascha&rft.date=2016-03-15&rft.volume=213&rft.issue=6&rft.spage=891&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiv549 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-05-01 N1 - Last updated - 2016-05-12 N1 - SubjectsTermNotLitGenreText - Reviews; antiretroviral therapy; Pathogens; Infection; Opportunist infection; Immunosuppression; Disease transmission; Infants; Infectious diseases; Human immunodeficiency virus; Antiretroviral agents; Human cytomegalovirus; Cytomegalovirus DO - http://dx.doi.org/10.1093/infdis/jiv549 ER - TY - JOUR T1 - Accurate Genetic Detection of Hepatitis C Virus Transmissions in Outbreak Settings AN - 1785235175; PQ0002903393 AB - Hepatitis C is a major public health problem in the United States and worldwide. Outbreaks of hepatitis C virus (HCV) infections are associated with unsafe injection practices, drug diversion, and other exposures to blood and are difficult to detect and investigate. Here, we developed and validated a simple approach for molecular detection of HCV transmissions in outbreak settings. We obtained sequences from the HCV hypervariable region 1 (HVR1), using end-point limiting-dilution (EPLD) technique, from 127 cases involved in 32 epidemiologically defined HCV outbreaks and 193 individuals with unrelated HCV strains. We compared several types of genetic distances and calculated a threshold, using minimal Hamming distances, that identifies transmission clusters in all tested outbreaks with 100% accuracy. The approach was also validated on sequences obtained using next-generation sequencing from HCV strains recovered from 239 individuals, and findings showed the same accuracy as that for EPLD. On average, the nucleotide diversity of the intrahost population was 6.2 times greater in the source case than in any incident case, allowing the correct detection of transmission direction in 8 outbreaks for which source cases were known. A simple and accurate distance-based approach developed here for detecting HCV transmissions streamlines molecular investigation of outbreaks, thus improving the public health capacity for rapid and effective control of hepatitis C. JF - Journal of Infectious Diseases AU - Campo, David S AU - Xia, Guo-Liang AU - Dimitrova, Zoya AU - Lin, Yulin AU - Forbi, Joseph C AU - Ganova-Raeva, Lilia AU - Punkova, Lili AU - Ramachandran, Sumathi AU - Thai, Hong AU - Skums, Pavel AD - Molecular Epidemiology and Bioinformatics Laboratory, Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, Georgia, fyv6@cdc.gov Y1 - 2016/03/15/ PY - 2016 DA - 2016 Mar 15 SP - 957 EP - 965 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 213 IS - 6 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - HCV KW - outbreak KW - threshold KW - NGS KW - nucleotide diversity KW - phylogenetic analysis KW - hamming distance KW - transmission networks KW - Infection KW - Nucleotides KW - Disease transmission KW - Public health KW - Blood KW - USA KW - Hepatitis C virus KW - Infectious diseases KW - Outbreaks KW - Hepatitis C KW - Genetic distance KW - Drugs KW - H 12000:Epidemiology and Public Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1785235175?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Accurate+Genetic+Detection+of+Hepatitis+C+Virus+Transmissions+in+Outbreak+Settings&rft.au=Campo%2C+David+S%3BXia%2C+Guo-Liang%3BDimitrova%2C+Zoya%3BLin%2C+Yulin%3BForbi%2C+Joseph+C%3BGanova-Raeva%2C+Lilia%3BPunkova%2C+Lili%3BRamachandran%2C+Sumathi%3BThai%2C+Hong%3BSkums%2C+Pavel&rft.aulast=Campo&rft.aufirst=David&rft.date=2016-03-15&rft.volume=213&rft.issue=6&rft.spage=957&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiv542 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-04-01 N1 - Last updated - 2016-08-03 N1 - SubjectsTermNotLitGenreText - Blood; Genetic distance; Hepatitis C; Infection; Drugs; Nucleotides; Public health; Disease transmission; Infectious diseases; Outbreaks; Hepatitis C virus; USA DO - http://dx.doi.org/10.1093/infdis/jiv542 ER - TY - JOUR T1 - Internal exposure to uranium in a pooled cohort of gaseous diffusion plant workers AN - 1787980691; PQ0002970900 AB - Intakes and absorbed organ doses were estimated for 29 303 workers employed at three former US gaseous diffusion plants as part of a study of cause-specific mortality and cancer incidence in uranium enrichment workers. Uranium urinalysis data (>600 000 urine samples) were available for 58 % of the pooled cohort. Facility records provided uranium gravimetric and radioactivity concentration data and allowed estimation of enrichment levels of uranium to which workers may have been exposed. Urine data were generally recorded with facility department numbers, which were also available in study subjects' work histories. Bioassay data were imputed for study subjects with no recorded sample results (33 % of pooled cohort) by assigning department average urine uranium concentration. Gravimetric data were converted to 24-h uranium activity excretion using department average specific activities. Intakes and organ doses were calculated assuming chronic exposure by inhalation to a 5- mu m activity median aerodynamic diameter aerosol of soluble uranium. Median intakes varied between 0.31 and 0.74 Bq d super(-1) for the three facilities. Median organ doses for the three facilities varied between 0.019 and 0.051, 0.68 and 1.8, 0.078 and 0.22, 0.28 and 0.74, and 0.094 and 0.25 mGy for lung, bone surface, red bone marrow, kidneys, and liver, respectively. Estimated intakes and organ doses for study subjects with imputed bioassay data were similar in magnitude. JF - Radiation Protection Dosimetry AU - Anderson, Jeri L AU - Apostoaei, A Iulian AU - Yiin, James H AU - Fleming, Donald A AU - Tseng, Chih-Yu AU - Chen, Pi-Hsueh AD - Division of Surveillance, Hazard Evaluations and Field Studies (DSHEFS), National Institute for Occupational Safety and Health (NIOSH), 1090 Tusculum Ave., MS R-14., Cincinnati, OH 45226, USA, jlanderson@cdc.gov Y1 - 2016/03// PY - 2016 DA - March 2016 SP - 471 EP - 477 PB - Oxford University Press, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 168 IS - 4 SN - 0144-8420, 0144-8420 KW - Environment Abstracts; Toxicology Abstracts KW - Inhalation KW - Bone marrow KW - Workers KW - Chronic exposure KW - Uranium KW - Diffusion KW - Radioactivity KW - Occupational exposure KW - Mortality KW - Aerosols KW - Dosimetry KW - Organs KW - Cancer KW - Bioassays KW - Lung KW - Urine KW - Kidney KW - Liver KW - Excretion KW - Urinalysis KW - X 24390:Radioactive Materials KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1787980691?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Radiation+Protection+Dosimetry&rft.atitle=Internal+exposure+to+uranium+in+a+pooled+cohort+of+gaseous+diffusion+plant+workers&rft.au=Anderson%2C+Jeri+L%3BApostoaei%2C+A+Iulian%3BYiin%2C+James+H%3BFleming%2C+Donald+A%3BTseng%2C+Chih-Yu%3BChen%2C+Pi-Hsueh&rft.aulast=Anderson&rft.aufirst=Jeri&rft.date=2016-03-01&rft.volume=168&rft.issue=4&rft.spage=471&rft.isbn=&rft.btitle=&rft.title=Radiation+Protection+Dosimetry&rft.issn=01448420&rft_id=info:doi/10.1093%2Frpd%2Fncv357 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-05-01 N1 - Last updated - 2016-07-07 N1 - SubjectsTermNotLitGenreText - Inhalation; Mortality; Aerosols; Dosimetry; Bone marrow; Cancer; Workers; Urine; Chronic exposure; Lung; Uranium; Liver; Kidney; Excretion; Diffusion; Radioactivity; Urinalysis; Occupational exposure; Organs; Bioassays DO - http://dx.doi.org/10.1093/rpd/ncv357 ER - TY - JOUR T1 - Age-Specific Race and Ethnicity Disparities in HIV Infection and Awareness Among Men Who Have Sex With Men[whitesquare]20 US Cities, 2008-2014 AN - 1780525950; PQ0002893214 AB - Background.?Over half of human immunodeficiency virus (HIV) infections in the United States occur among men who have sex with men (MSM). Among MSM, 16% of estimated new infections in 2010 occurred among black MSM <25 years old. Methodology.?We analyzed National HIV Behavioral Surveillance data on MSM from 20 cities. Poisson models were used to test racial disparities, by age, in HIV prevalence, HIV awareness, and sex behaviors among MSM in 2014. Data from 2008, 2011, and 2014 were used to examine how racial/ethnic disparities changed across time. Results.?While black MSM did not report greater sexual risk than other MSM, they were most likely to be infected with HIV and least likely to know it. Among black MSM aged 18-24 years tested in 2014, 26% were HIV positive. Among white MSM aged 18-24 years tested in 2014, 3% were HIV positive. The disparity in HIV prevalence between black and white MSM increased from 2008 to 2014, especially among young MSM. Conclusions.?Disparities in HIV prevalence between black and white MSM continue to increase. Black MSM may be infected with HIV at younger ages than other MSM and may benefit from prevention efforts that address the needs of younger men. JF - Journal of Infectious Diseases AU - Wejnert, Cyprian AU - Hess, Kristen L AU - Rose, Charles E AU - Balaji, Alexandra AU - Smith, Justin C AU - Paz-Bailey, Gabriela AD - Division of HIV/AIDS Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, cwejnert@cdc.gov Y1 - 2016/03/01/ PY - 2016 DA - 2016 Mar 01 SP - 776 EP - 783 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 213 IS - 5 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - HIV KW - MSM KW - health disparities KW - black MSM KW - Age KW - Data processing KW - Males KW - Homosexuality KW - Infection KW - Models KW - Cities KW - USA KW - Prevention KW - Infectious diseases KW - Behavior KW - Human immunodeficiency virus KW - Races KW - Ethnic groups KW - Sex KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - V 22360:AIDS and HIV UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1780525950?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Age-Specific+Race+and+Ethnicity+Disparities+in+HIV+Infection+and+Awareness+Among+Men+Who+Have+Sex+With+Men%5Bwhitesquare%5D20+US+Cities%2C+2008-2014&rft.au=Wejnert%2C+Cyprian%3BHess%2C+Kristen+L%3BRose%2C+Charles+E%3BBalaji%2C+Alexandra%3BSmith%2C+Justin+C%3BPaz-Bailey%2C+Gabriela&rft.aulast=Wejnert&rft.aufirst=Cyprian&rft.date=2016-03-01&rft.volume=213&rft.issue=5&rft.spage=776&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiv500 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-04-01 N1 - Last updated - 2016-08-03 N1 - SubjectsTermNotLitGenreText - Age; Data processing; Infection; Ethnic groups; Races; Models; Sex; Cities; Prevention; Behavior; Infectious diseases; Human immunodeficiency virus; Males; Homosexuality; USA DO - http://dx.doi.org/10.1093/infdis/jiv500 ER - TY - JOUR T1 - Elevated body mass index and decreased diet quality among women and risk of birth defects in their offspring. AN - 1775178020; 26663631 AB - We examined whether risks of 32 birth defects were higher than expected in the presence of overweight or obese body mass index (BMI) and low diet quality, based on estimating individual and joint effects of these factors and calculating relative excess risk due to interaction. Analyses included mothers of 20,250 cases with birth defects and 8617 population-based controls without birth defects born from 1997 to 2009 and interviewed for the National Birth Defects Prevention Study. We used logistic regression to generate adjusted odds ratios (AORs) reflecting the combined effects of BMI and diet quality. We focused analyses on 16 birth defects (n = 11,868 cases, 8617 controls) for which initial results suggested an association with BMI or diet quality. Relative to the reference group (normal weight women with not low diet quality, i.e., >lowest quartile), AORs for low diet quality among normal weight women tended to be >1, and AORs for overweight and obese women tended to be stronger among women who had low diet quality than not low diet quality. For 9/16 birth defects, AORs for obese women who had low diet quality-the group we hypothesized to have highest risk-were higher than other stratum-specific AORs. Most relative excess risk due to interactions were positive but small (<0.5), with confidence intervals that included zero. These findings provide evidence for the hypothesis of highest birth defect risks among offspring to women who are obese and have low diet quality but insufficient evidence for an interaction of these factors in their contribution to risk. © 2015 Wiley Periodicals, Inc. JF - Birth defects research. Part A, Clinical and molecular teratology AU - Carmichael, Suzan L AU - Yang, Wei AU - Gilboa, Suzanne AU - Ailes, Elizabeth AU - Correa, Adolfo AU - Botto, Lorenzo D AU - Feldkamp, Marcia L AU - Shaw, Gary M AU - National Birth Defects Prevention Study AD - Department of Pediatrics, Stanford University, Stanford, California. ; National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia. ; Departments of Medicine and Pediatrics, University of Mississippi Medical Center, Jackson, Mississippi. ; Division of Medical Genetics, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah. ; National Birth Defects Prevention Study Y1 - 2016/03// PY - 2016 DA - March 2016 SP - 164 EP - 171 VL - 106 IS - 3 KW - Index Medicus KW - neural tube defects KW - nutrition KW - diet KW - obesity KW - congenital anomalies KW - Odds Ratio KW - Humans KW - Mothers KW - Infant, Newborn KW - Feeding Behavior KW - Diet -- adverse effects KW - Pregnancy KW - Logistic Models KW - Risk Factors KW - Adult KW - Case-Control Studies KW - Female KW - Male KW - Pregnancy Complications -- etiology KW - Congenital Abnormalities -- prevention & control KW - Pregnancy Complications -- pathology KW - Congenital Abnormalities -- etiology KW - Body Mass Index KW - Obesity -- physiopathology KW - Congenital Abnormalities -- pathology KW - Obesity -- complications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1775178020?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Birth+defects+research.+Part+A%2C+Clinical+and+molecular+teratology&rft.atitle=Elevated+body+mass+index+and+decreased+diet+quality+among+women+and+risk+of+birth+defects+in+their+offspring.&rft.au=Schulte%2C+P+A%3BGeraci%2C+CL%3BMurashov%2C+V%3BKuempel%2C+ED%3BZumwalde%2C+R+D%3BCastranova%2C+V%3BHoover%2C+MD%3BHodson%2C+L%3BMartinez%2C+K+F&rft.aulast=Schulte&rft.aufirst=P&rft.date=2014-01-01&rft.volume=16&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Journal+of+Nanoparticle+Research&rft.issn=13880764&rft_id=info:doi/10.1007%2Fs11051-013-2153-9 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2016-12-13 N1 - Date created - 2016-03-21 N1 - Date revised - 2017-01-14 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1002/bdra.23471 ER - TY - JOUR T1 - Quantification of tetrabromo benzoic acid and tetrabromo phthalic acid in rats exposed to the flame retardant Uniplex FPR-45 AN - 1768576519; PQ0002673472 AB - The first withdrawal of certain polybrominated diphenyl ethers flame retardants from the US market occurred in 2004. Since then, use of brominated non-PBDE compounds such as bis(2-ethylhexyl)-2,3,4,5-tetrabromophthalate (BEH-TEBP) and 2-ethylhexyl-2,3,4,5-tetrabromobenzoate (EH-TBB) in commercial formulations has increased. Assessing human exposure to these chemicals requires identifying metabolites that can potentially serve as their biomarkers of exposure. We administered by gavage a dose of 500 mg/Kg bw of Uniplex FRP-45 (>95 % BEH-TEBP) to nine adult female Sprague-Dawley rats. Using authentic standards and mass spectrometry, we positively identified and quantified 2,3,4,5-tetrabromo benzoic acid (TBBA) and 2,3,4,5-tetrabromo phthalic acid (TBPA) in 24-h urine samples collected 1 day after dosing the rats and in serum at necropsy, 2 days post-exposure. Interestingly, TBBA and TBPA concentrations correlated well (R super(2) = 0.92). The levels of TBBA, a known metabolite of EH-TBB, were much higher than the levels of TBPA both in urine and serum. Because Uniplex FRP-45 was technical grade and EH-TBB was present in the formulation, TBBA likely resulted from the metabolism of EH-TBB. Taken together, our data suggest that TBBA and TBPA may serve as biomarkers of exposure to non-PBDE brominated flame retardant mixtures. Additional research can provide useful information to better understand the composition and in vivo toxicokinetics of these commercial mixtures. JF - Archives of Toxicology AU - Silva, Manori J AU - Hilton, Donald AU - Furr, Johnathan AU - Gray, LEarl AU - Preau, James L AU - Calafat, Antonia M AU - Ye, Xiaoyun AD - Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, 30341, USA, zca2@cdc.gov Y1 - 2016/03// PY - 2016 DA - March 2016 SP - 551 EP - 557 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 90 IS - 3 SN - 0340-5761, 0340-5761 KW - Health & Safety Science Abstracts; Toxicology Abstracts KW - Bioindicators KW - Chemicals KW - Autopsy KW - Benzoic acid KW - Data processing KW - Mass spectrometry KW - Metabolites KW - Fire retardant chemicals KW - biomarkers KW - Mass spectroscopy KW - Phthalic acid KW - Rats KW - Polybrominated diphenyl ethers KW - polybrominated diphenyl ethers KW - Urine KW - Fire retardants KW - Metabolism KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1768576519?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Archives+of+Toxicology&rft.atitle=Quantification+of+tetrabromo+benzoic+acid+and+tetrabromo+phthalic+acid+in+rats+exposed+to+the+flame+retardant+Uniplex+FPR-45&rft.au=Silva%2C+Manori+J%3BHilton%2C+Donald%3BFurr%2C+Johnathan%3BGray%2C+LEarl%3BPreau%2C+James+L%3BCalafat%2C+Antonia+M%3BYe%2C+Xiaoyun&rft.aulast=Silva&rft.aufirst=Manori&rft.date=2016-03-01&rft.volume=90&rft.issue=3&rft.spage=551&rft.isbn=&rft.btitle=&rft.title=Archives+of+Toxicology&rft.issn=03405761&rft_id=info:doi/10.1007%2Fs00204-015-1489-6 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Number of references - 17 N1 - Last updated - 2016-08-03 N1 - SubjectsTermNotLitGenreText - Autopsy; polybrominated diphenyl ethers; Data processing; Benzoic acid; Urine; Metabolites; Fire retardant chemicals; biomarkers; Mass spectroscopy; Phthalic acid; Chemicals; Polybrominated diphenyl ethers; Bioindicators; Rats; Mass spectrometry; Fire retardants; Metabolism DO - http://dx.doi.org/10.1007/s00204-015-1489-6 ER - TY - JOUR T1 - Loss to follow-up and bias assessment among a cohort of Thai men who have sex with men in Bangkok, Thailand AN - 1765985889; PQ0002593109 AB - Minimising loss to follow-up is essential to obtain unbiased results. This study aimed to assess factors associated with loss to follow-up and effects on biasing exposure-outcome associations in a cohort of men who have sex with men in Bangkok. We enrolled sexually-active Thai men who have sex with men, at least 18 years old, in a study with four-monthly follow-up visits. At each visit, men answered HIV risk behaviour questions using audio computer-assisted self-interview. Logistic regression was used to evaluate factors associated with loss to follow-up and bias between exposures and prevalent HIV infection were estimated using adjusted relative odds ratios. From 2006 to 2010, we enrolled 1744 men who have sex with men; as of April, 2014, 1256 (72%) had completed at least the month-36 visit; loss to follow-up was 9.6%. Factors independently associated with loss to follow-up were age (18-21 years), education (primary level or less, secondary or vocational education), living outside Bangkok and vicinity, sexual orientation (bisexual, heterosexual), previous HIV testing, HIV infection, and behaviour in the past 4 months (recreational drug use, reporting group sex). An effect of loss to follow-up on factors of prevalent HIV infection was found by sexual orientation (transgender) and unprotected anal intercourse (receptive/insertive). These findings highlight the need to strengthen post-HIV test counselling. Directed counselling for HIV care should be given to young men who have sex with men and recreational drug users. JF - International Journal of STD & AIDS AU - Pattanasin, Sarika AU - Wimonsate, Wipas AU - Chonwattana, Wannee AU - Tongtoyai, Jaray AU - Chaikummao, Supaporn AU - Sriporn, Anuwat AU - Sukwicha, Wichuda AU - Mock, Philip A AU - Holtz, Timothy H AD - 1 .Thailand Ministry of Public Health - US Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand, vpv6@cdc.gov Y1 - 2016/03// PY - 2016 DA - March 2016 SP - 196 EP - 206 PB - Sage Publications, Inc., 2455 Teller Road Thousand Oaks CA 91320 United States VL - 27 IS - 3 SN - 0956-4624, 0956-4624 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - HIV KW - AIDS KW - men KW - Epidemiology KW - homosexual KW - men who have sex with men KW - MSM KW - Asia KW - high-risk behaviour KW - prospective studies KW - loss to follow-up KW - Acquired immune deficiency syndrome KW - Age KW - Thailand, Chacoengsao Prov., Bangkok KW - Homosexuality KW - Anal sex KW - Infection KW - Drug abuse KW - Sexual behavior KW - Health risks KW - Education KW - Human immunodeficiency virus KW - Recreation areas KW - Bisexuality KW - Bisexual KW - Drugs KW - Sexually transmitted diseases KW - Sex KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1765985889?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+STD+%26+AIDS&rft.atitle=Loss+to+follow-up+and+bias+assessment+among+a+cohort+of+Thai+men+who+have+sex+with+men+in+Bangkok%2C+Thailand&rft.au=Pattanasin%2C+Sarika%3BWimonsate%2C+Wipas%3BChonwattana%2C+Wannee%3BTongtoyai%2C+Jaray%3BChaikummao%2C+Supaporn%3BSriporn%2C+Anuwat%3BSukwicha%2C+Wichuda%3BMock%2C+Philip+A%3BHoltz%2C+Timothy+H&rft.aulast=Pattanasin&rft.aufirst=Sarika&rft.date=2016-03-01&rft.volume=27&rft.issue=3&rft.spage=196&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+STD+%26+AIDS&rft.issn=09564624&rft_id=info:doi/10.1177%2F0956462415578954 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Number of references - 22 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Age; Bisexual; Drug abuse; Infection; Drugs; Sexual behavior; Sex; Health risks; Acquired immune deficiency syndrome; Education; Recreation areas; Human immunodeficiency virus; Bisexuality; Anal sex; Homosexuality; Sexually transmitted diseases; Thailand, Chacoengsao Prov., Bangkok DO - http://dx.doi.org/10.1177/0956462415578954 ER - TY - JOUR T1 - Epidemiology of Dengue Among Children Aged < 18 Months-Puerto Rico, 1999-2011 AN - 1787964227; PQ0002937386 AB - Dengue, a mosquito-borne viral illness caused by dengue virus types (DENV)-1 to DENV-4, is endemic in Puerto Rico. Severe dengue usually occurs in individuals previously infected with DENV or among infants born to previously infected mothers. To describe clinical features of dengue in infants, we retrospectively characterized dengue patients aged < 18 months reported to the Passive Dengue Surveillance System (PDSS) during 1999-2011. To determine frequency of signs, symptoms, and disease severity, case report forms and medical records were evaluated for patients who tested positive for dengue by reverse transcriptase polymerase chain reaction or anti-DENV immunoglobulin Menzyme-linked immunosorbent assay. Of 4,178 reported patients aged < 18 months, 813 (19%) were laboratory positive. Of these, most had fever (92%), rash (53%), bleeding manifestations (52%), and thrombocytopenia (52%). Medical records were available for 145 (31%) of 472 hospitalized patients, of which 40% had dengue, 23% had dengue with warning signs, and 33% had severe dengue. Mean age of patients with severe dengue was 8 months. Anti-DENV immunoglobulin G (IgG) titers were not statistically different in patients with (50%) and without (59%) severe dengue. In this study, one-third of DENV-infected infants met the severe dengue case definition. The role of maternal anti-DENV IgG in development of severe disease warrants further study in prospective cohorts of mother-infant pairs. JF - American Journal of Tropical Medicine and Hygiene AU - Hause, Anne M AU - Perez-Padilla, Janice AU - Horiuchi, Kalanthe AU - Han, George S AU - Hunsperger, Elizabeth AU - Aiwazian, Jonathan AU - Margolis, Harold S AU - Tomashek, Kay M AD - Dengue Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico, jperez@cdc.gov Y1 - 2016/02// PY - 2016 DA - February 2016 SP - 404 EP - 408 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 94 IS - 2 SN - 0002-9637, 0002-9637 KW - Virology & AIDS Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts KW - Dengue virus KW - Symptoms KW - Age KW - Human diseases KW - Nucleotide sequence KW - Immunosorbents KW - Public health KW - Fever KW - Exanthema KW - Endemic species KW - Thrombocytopenia KW - Dengue KW - Polymerase chain reaction KW - RNA-directed DNA polymerase KW - Aquatic insects KW - medical records KW - Surveillance and enforcement KW - Children KW - Case reports KW - Epidemiology KW - ASW, Caribbean Sea, Greater Antilles, Puerto Rico KW - Bleeding KW - Immunoglobulin G KW - Hygiene KW - Immunoassays KW - Hospitals KW - Infants KW - K 03400:Human Diseases KW - H 12000:Epidemiology and Public Health KW - Q1 08604:Stock assessment and management KW - Q5 08524:Public health, medicines, dangerous organisms KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1787964227?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Influenza+Viruses+in+Nigeria%2C+2009-2010%3A+Results+From+the+First+17+Months+of+a+National+Influenza+Sentinel+Surveillance+System&rft.au=Dalhatu%2C+Ibrahim+T%3BMedina-Marino%2C+Andrew%3BOlsen%2C+Sonja+J%3BHwang%2C+Inzune%3BGubio%2C+Aisha+Bintu%3BEkanem%2C+Ekanem+E%3BCoker%2C+E+B+A%3BAkpan%2C+Henry%3BAdedeji%2C+Adebayo+Abel&rft.aulast=Dalhatu&rft.aufirst=Ibrahim&rft.date=2012-12-15&rft.volume=206&rft.issue=&rft.spage=S121&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjis584 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-05-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Symptoms; Endemic species; Human diseases; Epidemiology; Nucleotide sequence; Surveillance and enforcement; Hygiene; Aquatic insects; Public health; Age; medical records; Children; Immunosorbents; Fever; Exanthema; Thrombocytopenia; Case reports; Dengue; Immunoglobulin G; Bleeding; RNA-directed DNA polymerase; Polymerase chain reaction; Infants; Immunoassays; Hospitals; Dengue virus; ASW, Caribbean Sea, Greater Antilles, Puerto Rico DO - http://dx.doi.org/10.4269/ajtmh.15-0382 ER - TY - JOUR T1 - A Cluster Randomized Controlled Evaluation of the Health Impact of a Novel Antimicrobial Hand Towel on the Health of Children Under 2 Years Old in Rural Communities in Nyanza Province, Kenya AN - 1787963411; PQ0002937392 AB - To assess the health impact of reusable, antimicrobial hand towels, we conducted a cluster randomized, yearlong field trial. At baseline, we surveyed mothers, and gave four towels plus hygiene education to intervention households and education alone to controls. At biweekly home visits, we asked about infections in children < 2 years old and tested post-handwashing hand rinse samples of 20% of mothers for Escherichia coli. At study's conclusion, we tested 50% of towels for E. coli. Baseline characteristics between 188 intervention and 181 control households were similar. Intervention and control children had similar rates of diarrhea (1.47 versus 1.48, P = 0.99), respiratory infections (1.38 versus 1.48, P = 0.92), skin infections (1.76 versus 1.79, P = 0.81), and subjective fever (2.62 versus 3.40, P = 0.04) per 100 person-visits. Post-handwashing hand contamination was similar; 67% of towels exhibited E. coli contamination. Antimicrobial hand towels became contaminated over time, did not improve hand hygiene, or prevent diarrhea, respiratory infections, or skin infections. JF - American Journal of Tropical Medicine and Hygiene AU - Slayton, Rachel B AU - Murphy, Jennifer L AU - Morris, Jamae AU - Faith, Sitnah Hamidah AU - Oremo, Jared AU - Odhiambo, Aloyce AU - Ayers, Tracy AU - Feinman, Shawna J AU - Brown, Allison C AU - Quick, Robert E AD - Division of Foodborne, Waterborne, and Environmental Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, via3@cdc.gov Y1 - 2016/02// PY - 2016 DA - February 2016 SP - 437 EP - 444 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 94 IS - 2 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Pollution Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts KW - Contamination KW - Respiration KW - Intervention KW - Microbial contamination KW - Infection KW - Fever KW - Kenya KW - Escherichia coli KW - Biological pollutants KW - Kenya, Nyanza KW - Skin KW - Diarrhea KW - Pathogenic bacteria KW - Hand KW - Children KW - Antimicrobial agents KW - Education KW - Households KW - Hygiene KW - Metabolism KW - Rural areas KW - A 01340:Antibiotics & Antimicrobials KW - K 03400:Human Diseases KW - H 1000:Occupational Safety and Health KW - Q1 08604:Stock assessment and management KW - Q5 08524:Public health, medicines, dangerous organisms KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1787963411?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=A+Cluster+Randomized+Controlled+Evaluation+of+the+Health+Impact+of+a+Novel+Antimicrobial+Hand+Towel+on+the+Health+of+Children+Under+2+Years+Old+in+Rural+Communities+in+Nyanza+Province%2C+Kenya&rft.au=Slayton%2C+Rachel+B%3BMurphy%2C+Jennifer+L%3BMorris%2C+Jamae%3BFaith%2C+Sitnah+Hamidah%3BOremo%2C+Jared%3BOdhiambo%2C+Aloyce%3BAyers%2C+Tracy%3BFeinman%2C+Shawna+J%3BBrown%2C+Allison+C%3BQuick%2C+Robert+E&rft.aulast=Slayton&rft.aufirst=Rachel&rft.date=2016-02-01&rft.volume=94&rft.issue=2&rft.spage=437&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0566 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-05-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Education; Contamination; Pathogenic bacteria; Respiration; Biological pollutants; Microbial contamination; Hygiene; Metabolism; Fever; Diarrhea; Skin; Hand; Children; Infection; Antimicrobial agents; Households; Intervention; Rural areas; Escherichia coli; Kenya; Kenya, Nyanza DO - http://dx.doi.org/10.4269/ajtmh.14-0566 ER - TY - JOUR T1 - Heat Stress Illness Emergency Department Visits in National Environmental Public Health Tracking States, 2005-2010 AN - 1773904565; PQ0002589032 AB - Variability of heat stress illness (HSI) by urbanicity and climate region has rarely been considered in previous HSI studies. We investigated temporal and geographic trends in HSI emergency department (ED) visits in CDC Environmental Public Health Tracking Network (Tracking) states for 2005-2010. We obtained county-level HSI ED visit data for 14 Tracking states. We used the National Center for Health Statistics Urban-Rural Classification Scheme to categorize counties by urbanicity as (1) large central metropolitan (LCM), (2) large fringe metropolitan, (3) small-medium metropolitan, or (4) nonmetropolitan (NM). We also assigned counties to one of six US climate regions. Negative binomial regression was used to examine trends in HSI ED visits over time across all counties and by urbanicity for each climate region, adjusting for pertinent variables. During 2005-2010, there were 98,462 HSI ED visits in the 14 states. ED visits for HSI decreased 3.0 % (p < 0.01) per year. Age-adjusted incidence rates of HSI ED visits increased from most urban to most rural. Overall, ED visits were significantly higher for NM areas (IRR = 1.41, p < 0.01) than for LCM areas. The same pattern was observed in all six climate regions; compared with LCM, NM areas had from 14 to 90 % more ED visits for HSI. These findings of significantly increased HSI ED visit rates in more rural settings suggest a need to consider HSI ED visit variability by county urbanicity and climate region when designing and implementing local HSI preventive measures and interventions. JF - Journal of Community Health AU - Fechter-Leggett, Ethan D AU - Vaidyanathan, Ambarish AU - Choudhary, Ekta AD - Environmental Health Tracking Branch, Division of Environmental Hazards and Health Effects, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Hwy NE, Mailstop F-60, Chamblee, GA, 30341, USA, iun8@cdc.gov Y1 - 2016/02// PY - 2016 DA - February 2016 SP - 57 EP - 69 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 41 IS - 1 SN - 0094-5145, 0094-5145 KW - Health & Safety Science Abstracts KW - Data collection KW - Classification KW - Climate KW - Heat tolerance KW - Intervention KW - Rural areas KW - Emergency medical services KW - Urban areas KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1773904565?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Community+Health&rft.atitle=Heat+Stress+Illness+Emergency+Department+Visits+in+National+Environmental+Public+Health+Tracking+States%2C+2005-2010&rft.au=Fechter-Leggett%2C+Ethan+D%3BVaidyanathan%2C+Ambarish%3BChoudhary%2C+Ekta&rft.aulast=Fechter-Leggett&rft.aufirst=Ethan&rft.date=2016-02-01&rft.volume=41&rft.issue=1&rft.spage=57&rft.isbn=&rft.btitle=&rft.title=Journal+of+Community+Health&rft.issn=00945145&rft_id=info:doi/10.1007%2Fs10900-015-0064-7 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-03-01 N1 - Number of references - 50 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Data collection; Classification; Climate; Heat tolerance; Intervention; Urban areas; Emergency medical services; Rural areas DO - http://dx.doi.org/10.1007/s10900-015-0064-7 ER - TY - JOUR T1 - Incidence and Predictors of Abnormal Anal Cytology Findings Among HIV-Infected Adults Receiving Contemporary Antiretroviral Therapy AN - 1773836529; PQ0002694571 AB - Background. Anal cancer rates are higher for human immunodeficiency virus (HIV)-infected adults than for uninfected adults. Limited published data exist characterizing the incidence of precursor lesions detected by anal cytology. Methods. The Study to Understand the Natural History of HIV/AIDS in the Era of Effective Therapy was a prospective cohort of 700 HIV-infected participants in 4 US cities. At baseline and annually thereafter, each participant completed a behavioral questionnaire, and healthcare professionals collected anorectal swabs for cytologic examination and human papillomavirus (HPV) detection and genotyping. Results. Among 243 participants with negative baseline results of anal cytology, 37% developed abnormal cytology findings (incidence rate, 13.9 cases/100 person-years of follow-up; 95% confidence interval [CI], 11.3-16.9) over a median follow-up duration of 2.1 years. Rates among men having sex with men, among women, and among men having sex with women were 17.9 cases/person-years of follow-up (95% CI, 13.9-22.7), 9.4 cases/person-years of follow-up (95% CI, 5.6-14.9), and 8.9 cases/person-years of follow-up (95% CI, 4.8-15.6), respectively. In multivariable analysis, the number of persistent high-risk HPV types (adjusted hazard ratio [aHR], 1.17; 95% CI, 1.01-1.36), persistent high-risk HPV types except 16 or 18 (aHR, 2.46; 95% CI, 1.31-4.60), and persistent types 16 or 18 (aHR, 3.90; 95% CI, 1.78-8.54) remained associated with incident abnormalities. Conclusions. The incidence of abnormal anal cytology findings was high and more likely to develop among persons with persistent high-risk HPV. JF - Journal of Infectious Diseases AU - Conley, Lois J AU - Bush, Timothy J AU - Darragh, Teresa M AU - Palefsky, Joel M AU - Unger, Elizabeth R AU - Patel, Pragna AU - Steinau, Martin AU - Kojic, E Milu AU - Martin, Harold AU - Overton, E Turner AD - Division of HIV/AIDS Prevention, National Center for HIV, Hepatitis, STD, and TB Prevention, ljc2@cdc.gov Y1 - 2016/02/01/ PY - 2016 DA - 2016 Feb 01 SP - 351 EP - 360 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 213 IS - 3 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - abnormal anal cytology KW - HPV KW - HIV KW - incidence KW - persistence KW - Historical account KW - Inventories KW - Acquired immune deficiency syndrome KW - Data processing KW - Genotyping KW - antiretroviral therapy KW - Anorectal KW - Antiretroviral agents KW - Medical personnel KW - Cancer KW - Cities KW - Infectious diseases KW - Human immunodeficiency virus KW - Cytology KW - Lesions KW - Risk groups KW - Human papillomavirus KW - Sex KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - V 22360:AIDS and HIV UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1773836529?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Incidence+and+Predictors+of+Abnormal+Anal+Cytology+Findings+Among+HIV-Infected+Adults+Receiving+Contemporary+Antiretroviral+Therapy&rft.au=Conley%2C+Lois+J%3BBush%2C+Timothy+J%3BDarragh%2C+Teresa+M%3BPalefsky%2C+Joel+M%3BUnger%2C+Elizabeth+R%3BPatel%2C+Pragna%3BSteinau%2C+Martin%3BKojic%2C+E+Milu%3BMartin%2C+Harold%3BOverton%2C+E+Turner&rft.aulast=Conley&rft.aufirst=Lois&rft.date=2016-02-01&rft.volume=213&rft.issue=3&rft.spage=351&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiv408 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-03-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Inventories; Acquired immune deficiency syndrome; Data processing; Genotyping; antiretroviral therapy; Risk groups; Anorectal; Cancer; Sex; Historical account; Cities; Infectious diseases; Human immunodeficiency virus; Lesions; Cytology; Antiretroviral agents; Medical personnel; Human papillomavirus DO - http://dx.doi.org/10.1093/infdis/jiv408 ER - TY - JOUR T1 - Health Risk Behaviors by Length of Time in the United States Among High School Students in Five Sites AN - 1765979464; PQ0002588364 AB - One in five public school students is from an immigrant-headed household. We used Youth Risk Behavior Survey data from one state and four large urban school districts to examine whether length of time living in the US was associated with health risk behaviors. Logistic regression models, using weighted data, controlled for sex, race/ethnicity, and grade. Compared to US natives, not having always lived in the US was correlated with lower risk for some behaviors (e.g., current marijuana use and alcohol use) among high school students, but higher risk for other behaviors (e.g., attempted suicide, physical inactivity). Many findings were inconsistent across the study sites. Interventions that specifically target recently-arrived school-aged youth to prevent behaviors that put health and safety at risk, may result in the best outcomes for immigrant youth. Care should be taken to understand the specific health risks present in different immigrant communities. JF - Journal of Immigrant and Minority Health AU - Jones, Sherry Everett AU - Pezzi, Clelia AU - Rodriguez-Lainz, Alfonso AU - Whittle, Lisa AD - Division of Adolescent and School Health, Centers for Disease Control and Prevention, 1600 Clifton Rd, NE, MS-E75, Atlanta, GA, 30329, USA, sce2@cdc.gov Y1 - 2016/02// PY - 2016 DA - February 2016 SP - 150 EP - 160 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 18 IS - 1 SN - 1557-1912, 1557-1912 KW - Health & Safety Science Abstracts KW - Alcohol KW - Physical activity KW - Safety KW - Immigrants KW - Suicide KW - Intervention KW - Risk taking KW - Health risks KW - USA KW - Schools KW - Behavior KW - Households KW - Ethnic groups KW - Adolescents KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1765979464?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Immigrant+and+Minority+Health&rft.atitle=Health+Risk+Behaviors+by+Length+of+Time+in+the+United+States+Among+High+School+Students+in+Five+Sites&rft.au=Jones%2C+Sherry+Everett%3BPezzi%2C+Clelia%3BRodriguez-Lainz%2C+Alfonso%3BWhittle%2C+Lisa&rft.aulast=Jones&rft.aufirst=Sherry&rft.date=2016-02-01&rft.volume=18&rft.issue=1&rft.spage=150&rft.isbn=&rft.btitle=&rft.title=Journal+of+Immigrant+and+Minority+Health&rft.issn=15571912&rft_id=info:doi/10.1007%2Fs10903-014-0151-3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Number of references - 33 N1 - Last updated - 2016-02-29 N1 - SubjectsTermNotLitGenreText - Alcohol; Physical activity; Safety; Immigrants; Risk taking; Intervention; Suicide; Health risks; Schools; Behavior; Households; Adolescents; Ethnic groups; USA DO - http://dx.doi.org/10.1007/s10903-014-0151-3 ER - TY - JOUR T1 - Detection and measurement of surface contamination by multiple antineoplastic drugs using multiplex bead assay AN - 1762369436; PQ0002425646 AB - Objectives Contamination of workplace surfaces by antineoplastic drugs presents an exposure risk for healthcare workers. Traditional instrumental methods to detect contamination such as liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS) are sensitive and accurate but expensive. Since immunochemical methods may be cheaper and faster than instrumental methods, we wanted to explore their use for routine drug residue detection for preventing worker exposure. Methods In this study we examined the feasibility of using fluorescence covalent microbead immunosorbent assay (FCMIA) for simultaneous detection and semi-quantitative measurement of three antineoplastic drugs (5-fluorouracil, paclitaxel, and doxorubicin). The concentration ranges for the assay were 0-1000ng/ml for 5-fluorouracil, 0-100ng/ml for paclitaxel, and 0-2ng/ml for doxorubicin. The surface sampling technique involved wiping a loaded surface with a swab wetted with wash buffer, extracting the swab in storage/blocking buffer, and measuring drugs in the extract using FCMIA. Results There was no significant cross-reactivity between these drugs at the ranges studied indicated by a lack of response in the assay to cross analytes. The limit of detection (LOD) for 5-fluorouracil on the surface studied was 0.93ng/cm 2 with a limit of quantitation (LOQ) of 2.8ng/cm 2 , the LOD for paclitaxel was 0.57ng/cm 2 with an LOQ of 2.06ng/cm 2 , and the LOD for doxorubicin was 0.0036ng/cm 2 with an LOQ of 0.013ng/cm 2 . Conclusion The use of FCMIA with a simple sampling technique has potential for low cost simultaneous detection and semi-quantitative measurement of surface contamination from multiple antineoplastic drugs. JF - Journal of Oncology Pharmacy Practice AU - Smith, Jerome P AU - Sammons, Deborah L AU - Robertson, Shirley A AU - Pretty, Jack R AU - DeBord, D Gayle AU - Connor, Thomas H AU - Snawder, John E AD - Division of Applied Research & Technology, National institute for Occupational Safety & Health, Cincinnati, OH, USA, jps3@cdc.gov Y1 - 2016/02// PY - 2016 DA - February 2016 SP - 60 EP - 67 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU United Kingdom VL - 22 IS - 1 SN - 1078-1552, 1078-1552 KW - Pollution Abstracts; Health & Safety Science Abstracts KW - Antineoplastic drugs (5-fluorouracil KW - paclitaxel KW - doxorubicin) KW - surface analysis KW - multiplex measurement KW - Feasibility studies KW - Fluorescence KW - Contamination KW - Residues KW - Assays KW - Mass spectrometry KW - Antineoplastic drugs KW - Medical personnel KW - Spectrometry KW - Storage KW - Buffers KW - Immunoassays KW - Drugs KW - Occupational exposure KW - H 1000:Occupational Safety and Health KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1762369436?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Oncology+Pharmacy+Practice&rft.atitle=Detection+and+measurement+of+surface+contamination+by+multiple+antineoplastic+drugs+using+multiplex+bead+assay&rft.au=Smith%2C+Jerome+P%3BSammons%2C+Deborah+L%3BRobertson%2C+Shirley+A%3BPretty%2C+Jack+R%3BDeBord%2C+D+Gayle%3BConnor%2C+Thomas+H%3BSnawder%2C+John+E&rft.aulast=Smith&rft.aufirst=Jerome&rft.date=2016-02-01&rft.volume=22&rft.issue=1&rft.spage=60&rft.isbn=&rft.btitle=&rft.title=Journal+of+Oncology+Pharmacy+Practice&rft.issn=10781552&rft_id=info:doi/10.1177%2F1078155214554407 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Number of references - 15 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Feasibility studies; Fluorescence; Residues; Contamination; Antineoplastic drugs; Mass spectrometry; Assays; Medical personnel; Spectrometry; Storage; Buffers; Drugs; Immunoassays; Occupational exposure DO - http://dx.doi.org/10.1177/1078155214554407 ER - TY - JOUR T1 - Pre-Travel Medical Preparation of Business and Occupational Travelers: An Analysis of the Global TravEpiNet Consortium, 2009 to 2012 AN - 1808688365; PQ0003412154 AB - Objectives: The aim of the study was to understand more about pre-travel preparations and itineraries of business and occupational travelers. Methods: De-identified data from 18 Global TravEpiNet clinics from January 2009 to December 2012 were analyzed. Results: Of 23,534 travelers, 61% were non-occupational and 39% occupational. Business travelers were more likely to be men, had short times to departure and shorter trip durations, and commonly refused influenza, meningococcal, and hepatitis B vaccines. Most business travelers indicated that employers suggested the pre-travel health consultation, whereas non-occupational travelers sought consultations because of travel health concerns. Conclusions: Sub-groups of occupational travelers have characteristic profiles, with business travelers being particularly distinct. Employers play a role in encouraging business travelers to seek pre-travel consultations. Such consultations, even if scheduled immediately before travel, can identify vaccination gaps and increase coverage. JF - Journal of Occupational and Environmental Medicine AU - Khan, Nomana M AU - Jentes, Emily S AU - Brown, Clive AU - Han, Pauline AU - Rao, Sowmya R AU - Kozarsky, Phyllis AU - Hagmann, Stefan HF AU - LaRocque, Regina C AU - Ryan, Edward T AD - Division of Global Migration and Quarantine, Centers for Disease Control and Prevention, Atlanta, Georgia, efj8@cdc.gov Y1 - 2016/01// PY - 2016 DA - January 2016 SP - 76 EP - 82 PB - Williams & Wilkins, 351 W. Camden St. Baltimore MD 21201 United States VL - 58 IS - 1 SN - 1076-2752, 1076-2752 KW - Toxicology Abstracts; Health & Safety Science Abstracts KW - Travel KW - Influenza KW - Data processing KW - Hepatitis B virus KW - Hepatitis B KW - Neisseria meningitidis KW - Vaccines KW - X 24310:Pharmaceuticals KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808688365?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Pre-Travel+Medical+Preparation+of+Business+and+Occupational+Travelers%3A+An+Analysis+of+the+Global+TravEpiNet+Consortium%2C+2009+to+2012&rft.au=Khan%2C+Nomana+M%3BJentes%2C+Emily+S%3BBrown%2C+Clive%3BHan%2C+Pauline%3BRao%2C+Sowmya+R%3BKozarsky%2C+Phyllis%3BHagmann%2C+Stefan+HF%3BLaRocque%2C+Regina+C%3BRyan%2C+Edward+T&rft.aulast=Khan&rft.aufirst=Nomana&rft.date=2016-01-01&rft.volume=58&rft.issue=1&rft.spage=76&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0000000000000602 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-09-01 N1 - SubjectsTermNotLitGenreText - Influenza; Travel; Data processing; Hepatitis B; Vaccines; Hepatitis B virus; Neisseria meningitidis DO - http://dx.doi.org/10.1097/JOM.0000000000000602 ER - TY - JOUR T1 - Malaria Prevention Strategies: Adherence Among Boston Area Travelers Visiting Malaria-Endemic Countries AN - 1765976959; PQ0002580209 AB - We conducted a prospective cohort study to assess adherence to malaria chemoprophylaxis, reasons for nonadherence, and use of other personal protective measures against malaria. We included adults traveling to malaria-endemic countries who were prescribed malaria chemoprophylaxis during a pre-travel consultation at three travel clinics in the Boston area and who completed three or more surveys: pre-travel, at least one weekly during travel, and post-travel (2-4 weeks after return). Of 370 participants, 335 (91%) took malaria chemoprophylaxis at least once and reported any missed doses; 265 (79%) reported completing all doses during travel. Adherence was not affected by weekly versus daily chemoprophylaxis, travel purpose, or duration of travel. Reasons for nonadherence included forgetfulness, side effects, and not seeing mosquitoes. Main reasons for declining to take prescribed chemoprophylaxis were peer advice, low perceived risk, and not seeing mosquitoes. Of 368 travelers, 79% used insect repellent, 46% used a bed net, and 61% slept in air conditioning at least once. Because travelers may be persuaded to stop taking medication by peer pressure, not seeing mosquitoes, and adverse reactions to medications, clinicians should be prepared to address these barriers and to empower travelers with strategies to manage common side effects of antimalarial medications. JF - American Journal of Tropical Medicine and Hygiene AU - Stoney, Rhett J AU - Chen, Lin H AU - Jentes, Emily S AU - Wilson, Mary E AU - Han, Pauline V AU - Benoit, Christine M AU - Macleod, William B AU - Hamer, Davidson H AU - Barnett, Elizabeth D AD - Division of Global Migration and Quarantine, Centers for Disease Control and Prevention, Atlanta, Georgia, uyn2@cdc.gov Y1 - 2016/01// PY - 2016 DA - January 2016 SP - 136 EP - 142 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 94 IS - 1 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts KW - Risk assessment KW - Travel KW - Human diseases KW - Barriers KW - Air conditioning KW - Malaria KW - USA, Massachusetts, Boston KW - Risk factors KW - Repellents KW - Pressure KW - Drugs KW - Aquatic insects KW - Pest control KW - Insects KW - Prevention KW - Perception KW - Hygiene KW - Side effects KW - K 03400:Human Diseases KW - Q1 08604:Stock assessment and management KW - Q5 08524:Public health, medicines, dangerous organisms KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1765976959?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Malaria+Prevention+Strategies%3A+Adherence+Among+Boston+Area+Travelers+Visiting+Malaria-Endemic+Countries&rft.au=Stoney%2C+Rhett+J%3BChen%2C+Lin+H%3BJentes%2C+Emily+S%3BWilson%2C+Mary+E%3BHan%2C+Pauline+V%3BBenoit%2C+Christine+M%3BMacleod%2C+William+B%3BHamer%2C+Davidson+H%3BBarnett%2C+Elizabeth+D&rft.aulast=Stoney&rft.aufirst=Rhett&rft.date=2016-01-01&rft.volume=94&rft.issue=1&rft.spage=136&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.15-0565 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Human diseases; Barriers; Air conditioning; Repellents; Pest control; Malaria; Hygiene; Aquatic insects; Travel; Risk factors; Pressure; Side effects; Risk assessment; Prevention; Perception; Drugs; Insects; USA, Massachusetts, Boston DO - http://dx.doi.org/10.4269/ajtmh.15-0565 ER - TY - JOUR T1 - Expanding Range of Amblyomma americanum and Simultaneous Changes in the Epidemiology of Spotted Fever Group Rickettsiosis in the United States AN - 1765973320; PQ0002580192 AB - Spotted fever group (SFC) Rickettsia species are etiologic agents of a wide range of human infections from asymptomatic or mild infections to severe, life-threatening disease. In the United States, recent passive surveillance for SFC rickettsiosis shows an increased incidence and decreased severity of reported cases. The reasons for this are not well understood; however, we hypothesize that less pathogenic rickettsiae are causing more human infections, while the incidence of disease caused by more pathogenic rickettsiae, particularly Rickettsia rickettsii, is relatively stable. During the same period, the range of Amblyomma americanum has expanded. Amblyomma americanum is frequently infected with "Candidatus Rickettsia amblyommii", a SFC Rickettsia of unknown pathogenicity. We tested our hypothesis by modeling incidence rates from 1993 to 2013, hospitalization rates from 1981 to 2013, and case fatality rates from 1981 to 2013 regressed against the presence of A. americanum, the decade of onset of symptoms, and the county of residence. Our results support the hypothesis, and we show that the expanding range of A. americanum is associated with changes in epidemiology reported through passive surveillance. We believe epidemiological and acarological data collected on individual cases from enhanced surveillance may further elucidate the reasons for the changing epidemiology of SFC rickettsiosis. JF - American Journal of Tropical Medicine and Hygiene AU - Dahlgren, F Scott AU - Paddock, Christopher D AU - Springer, Yuri P AU - Eisen, Rebecca J AU - Behravesh, Casey Barton AD - Rickettsial Zoonoses Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, iot0@cdc.gov Y1 - 2016/01// PY - 2016 DA - January 2016 SP - 35 EP - 42 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 94 IS - 1 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Entomology Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts KW - Mortality KW - Symptoms KW - Geographical distribution KW - Data processing KW - Surveillance and enforcement KW - Rickettsiosis KW - Infection KW - Public health KW - Amblyomma americanum KW - USA KW - Spotted fevers KW - Pathogenicity KW - Epidemiology KW - Rickettsia rickettsii KW - Hygiene KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - K 03400:Human Diseases KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - Q1 08604:Stock assessment and management KW - J 02400:Human Diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1765973320?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Expanding+Range+of+Amblyomma+americanum+and+Simultaneous+Changes+in+the+Epidemiology+of+Spotted+Fever+Group+Rickettsiosis+in+the+United+States&rft.au=Dahlgren%2C+F+Scott%3BPaddock%2C+Christopher+D%3BSpringer%2C+Yuri+P%3BEisen%2C+Rebecca+J%3BBehravesh%2C+Casey+Barton&rft.aulast=Dahlgren&rft.aufirst=F&rft.date=2016-01-01&rft.volume=94&rft.issue=1&rft.spage=35&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.15-0580 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Symptoms; Geographical distribution; Epidemiology; Surveillance and enforcement; Hygiene; Public health; Data processing; Spotted fevers; Pathogenicity; Rickettsiosis; Infection; Mortality; Amblyomma americanum; Rickettsia rickettsii; USA DO - http://dx.doi.org/10.4269/ajtmh.15-0580 ER - TY - JOUR T1 - National Surveillance of Spotted Fever Group Rickettsioses in the United States, 2008-2012 AN - 1765973318; PQ0002580191 AB - Spotted fever group (SFG) rickettsioses are notifiable conditions in the United States caused by the highly pathogenic Rickettsia rickettsii and less pathogenic rickettsial species such as Rickettsia parkeri and Rickettsia sp. 364D. Surveillance data from 2008 to 2012 for SFG rickettsioses are summarized. Incidence increased from 1.7 cases per million person-years (PY) in 2000 to 14.3 cases per million PY in 2012. During 2008-2012, cases of SFG rickettsiosis were more frequently reported among males, persons of white race, and non-Hispanic ethnicity. Overall, case fatality rate (CFR) was low (0.4%), however, risk of death was significantly higher for American Indian/Alaska Natives (relative risk [RR] = 5.4) and Asian/Pacific Islanders (RR = 5.7) compared with persons of white race. Children aged < 10 years continue to experience the highest CFR (1.6%). Higher incidence of SFG rickettsioses and decreased CFR likely result from increased reporting of tick-borne disease including those caused by less pathogenic species. Recently, fewer cases have been confirmed using species-specific laboratory methods (such as cell culture and DNA detection using polymerase chain reaction [PCR] assays), causing a clouded epidemiological picture. Use of PCR and improved documentation of clinical signs, such as eschars, will better differentiate risk factors, incidence, and clinical outcomes of specific rickettsioses in the future. JF - American Journal of Tropical Medicine and Hygiene AU - Drexler, Naomi A AU - Dahlgren, F Scott AU - Heitman, Kristen Nichols AU - Massung, Robert F AU - Paddock, Christopher D AU - Behravesh, Casey Barton AD - Rickettsial Zoonoses Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, isj3@cdc.gov Y1 - 2016/01// PY - 2016 DA - January 2016 SP - 26 EP - 34 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 94 IS - 1 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts KW - Nucleotide sequence KW - Rickettsiosis KW - Cell culture KW - Laboratory methods KW - Risk factors KW - tick-borne diseases KW - Polymerase chain reaction KW - Rickettsia rickettsii KW - Races KW - Ethnic groups KW - Mortality KW - Data processing KW - Subpopulations KW - Surveillance and enforcement KW - INE, USA, Alaska KW - Pathogens KW - Children KW - Spotted fevers KW - DNA KW - Hygiene KW - Rickettsia parkeri KW - K 03400:Human Diseases KW - Q1 08604:Stock assessment and management KW - J 02400:Human Diseases KW - H 12000:Epidemiology and Public Health KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1765973318?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=National+Surveillance+of+Spotted+Fever+Group+Rickettsioses+in+the+United+States%2C+2008-2012&rft.au=Drexler%2C+Naomi+A%3BDahlgren%2C+F+Scott%3BHeitman%2C+Kristen+Nichols%3BMassung%2C+Robert+F%3BPaddock%2C+Christopher+D%3BBehravesh%2C+Casey+Barton&rft.aulast=Drexler&rft.aufirst=Naomi&rft.date=2016-01-01&rft.volume=94&rft.issue=1&rft.spage=26&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.15-0472 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Subpopulations; Nucleotide sequence; Surveillance and enforcement; DNA; Polymerase chain reaction; Cell culture; Pathogens; Hygiene; Data processing; Spotted fevers; Risk factors; tick-borne diseases; Rickettsiosis; Children; Ethnic groups; Races; Mortality; Laboratory methods; Rickettsia rickettsii; Rickettsia parkeri; INE, USA, Alaska DO - http://dx.doi.org/10.4269/ajtmh.15-0472 ER - TY - JOUR T1 - Molecular Investigation into a Malaria Outbreak in Cusco, Peru: Plasmodium falciparum B sub(V1) Lineage is Linked to a Second Outbreak in Recent Times AN - 1765973154; PQ0002580206 AB - In November 2013, a Plasmodium falciparum malaria outbreak of 11 cases occurred in Cusco, southern Peru, where falciparum malaria had not been reported since 1946. Although initial microscopic diagnosis reported only Plasmodium vivax infection in each of the specimens, subsequent examination by the national reference laboratory confirmed P. falciparum infection in all samples. Molecular typing of four available isolates revealed identity as the B-variant (B sub(V1)) strain that was responsible for a malaria outbreak in Tumbes, northern Peru, between 2010 and 2012. The P. falciparum B sub(V1) strain is multidrug resistant, can escape detection by PfHRP2-based rapid diagnostic tests, and has contributed to two malaria outbreaks in Peru. This investigation highlights the importance of accurate species diagnosis given the potential for P. falciparum to be reintroduced to regions where it may have been absent. Similar molecular epidemiological investigations can track the probable source(s) of outbreak parasite strains for malaria surveillance and control purposes. JF - American Journal of Tropical Medicine and Hygiene AU - Okoth, Sheila Akinyi AU - Chenet, Stella M AU - Arrospide, Nancy AU - Gutierrez, Sonia AU - Cabezas, Cesar AU - Matta, Jose Antonio AU - Udhayakumar, Venkatachalam AD - Malaria Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, jyo3@cdc.gov Y1 - 2016/01// PY - 2016 DA - January 2016 SP - 128 EP - 131 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 94 IS - 1 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts KW - Biological surveys KW - Parasites KW - Human diseases KW - Plasmodium vivax KW - Malaria KW - Plasmodium falciparum KW - Infection KW - Peru, Tumbes KW - Public health KW - Typing KW - Multidrug resistance KW - Outbreaks KW - Hygiene KW - ISE, Peru KW - K 03400:Human Diseases KW - Q1 08604:Stock assessment and management KW - H 12000:Epidemiology and Public Health KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1765973154?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Molecular+Investigation+into+a+Malaria+Outbreak+in+Cusco%2C+Peru%3A+Plasmodium+falciparum+B+sub%28V1%29+Lineage+is+Linked+to+a+Second+Outbreak+in+Recent+Times&rft.au=Okoth%2C+Sheila+Akinyi%3BChenet%2C+Stella+M%3BArrospide%2C+Nancy%3BGutierrez%2C+Sonia%3BCabezas%2C+Cesar%3BMatta%2C+Jose+Antonio%3BUdhayakumar%2C+Venkatachalam&rft.aulast=Okoth&rft.aufirst=Sheila&rft.date=2016-01-01&rft.volume=94&rft.issue=1&rft.spage=128&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.15-0442 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Biological surveys; Parasites; Human diseases; Malaria; Hygiene; Public health; Typing; Multidrug resistance; Infection; Outbreaks; Plasmodium vivax; Plasmodium falciparum; ISE, Peru; Peru, Tumbes DO - http://dx.doi.org/10.4269/ajtmh.15-0442 ER - TY - JOUR T1 - Human anthrax outbreak associated with livestock exposure: Georgia, 2012 AN - 1762381755; PQ0002459188 AB - Human anthrax cases reported in the country of Georgia increased 75% from 2011 (n = 81) to 2012 (n = 142). This increase prompted a case-control investigation using 67 culture- or PCR-confirmed cases and 134 controls matched by residence and gender to investigate risk factor(s) for infection during the month before case onset. Independent predictors most strongly associated with disease in the multivariable modelling were slaughtering animals [odds ratio (OR) 7.3, 95% confidence interval (CI) 2.9-18.1, P 1 km; 15 (12%) of 125 had sick livestock; and 11 (9%) of 128 respondents reported finding dead livestock. We recommend joint public health and veterinary anthrax case investigations to identify areas of increased risk for livestock anthrax outbreaks, annual anthrax vaccination of livestock in those areas, and public awareness education. JF - Epidemiology and Infection AU - NAVDARASHVILI, A AU - Doker, T J AU - GELEISHVILI, M AU - HABERLING, D L AU - Kharod, G A AU - Rush, Th AU - Maes, E AU - ZAKHASHVILI, K AU - IMNADZE, P AU - Bower, Wa AU - Walke, H T AU - SHADOMY, S V AD - Georgia National Center for Disease Control and Public Health, Georgia Ministry of Health, Tbilisi, Georgia, thomas.doker@gmail.com Y1 - 2016/01// PY - 2016 DA - January 2016 SP - 76 EP - 87 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 144 IS - 1 SN - 0950-2688, 0950-2688 KW - Health & Safety Science Abstracts KW - Infection KW - Livestock KW - Public health KW - Public awareness KW - Health risks KW - ASW, USA, Georgia KW - Education KW - Risk factors KW - Gender KW - Anthrax KW - Outbreaks KW - Vaccines KW - H 6000:Natural Disasters/Civil Defense/Emergency Management UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1762381755?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Human+anthrax+outbreak+associated+with+livestock+exposure%3A+Georgia%2C+2012&rft.au=NAVDARASHVILI%2C+A%3BDoker%2C+T+J%3BGELEISHVILI%2C+M%3BHABERLING%2C+D+L%3BKharod%2C+G+A%3BRush%2C+Th%3BMaes%2C+E%3BZAKHASHVILI%2C+K%3BIMNADZE%2C+P%3BBower%2C+Wa%3BWalke%2C+H+T%3BSHADOMY%2C+S+V&rft.aulast=NAVDARASHVILI&rft.aufirst=A&rft.date=2016-01-01&rft.volume=144&rft.issue=1&rft.spage=76&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268815001442 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Number of references - 22 N1 - Last updated - 2016-03-30 N1 - SubjectsTermNotLitGenreText - Health risks; Education; Risk factors; Gender; Anthrax; Vaccines; Outbreaks; Infection; Public awareness; Public health; Livestock; ASW, USA, Georgia DO - http://dx.doi.org/10.1017/S0950268815001442 ER - TY - JOUR T1 - Genital infections and syndromic diagnosis among HIV-infected women in HIV care programmes in Kenya AN - 1762377959; PQ0002525286 AB - Control of genital infections remains challenging in most regions. Despite advocacy by the World Health Organization for syndromic case management, there are limited data on the syndromic approach, especially in HIV care settings. This study compared the syndromic approach with laboratory diagnosis among women in HIV care in Kenya. A mobile team visited 39 large HIV care programmes in Kenya and enrolled participants using population-proportionate sampling. Participants provided behavioural and clinical data with genital and blood specimens for lab testing. Among 1063 women, 68.4% had been on antiretroviral therapy >1 year; 58.9% were using cotrimoxazole prophylaxis; 51 % had CD4+T-lymphocytes<350 cells/ mu L. Most women (63.1%) reported at least one genital symptom. Clinical signs were found in 63% of women; and 30.8% had an aetiological diagnosis. Bacterial vaginosis (17.4%), vaginal candidiasis (10.6%) and trichomoniasis (10.5%) were the most common diagnoses. Using laboratory diagnoses as gold standard, sensitivity and positive predictive value of the syndromic diagnosis for vaginal discharge were 47.6% and 52.7%, respectively, indicating a substantial amount of overtreatment. A systematic physical examination increased by 9.3% the positive predictive value for genital ulcer disease. Women attending HIV care programmes in Kenya have high rates of vaginal infections. Syndromic diagnosis was a poor predictor of those infections. JF - International Journal of STD & AIDS AU - Djomand, Gaston AU - Gao, Hongjiang AU - Singa, Benson AU - Hornston, Sureyya AU - Bennett, Eddas AU - Odek, James AU - McClelland, R Scott AU - John-Stewart, Grace AU - Bock, Naomi AD - 1 .US Centers for Disease Control and Prevention, Atlanta, GA, USA, gdd7@cdc.gov Y1 - 2016/01// PY - 2016 DA - January 2016 SP - 19 EP - 24 PB - Sage Publications, Inc., 2455 Teller Road Thousand Oaks CA 91320 United States VL - 27 IS - 1 SN - 0956-4624, 0956-4624 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - HIV KW - AIDS KW - sexually transmitted infections KW - women KW - Genital infections KW - syndromic management KW - vaginal discharge KW - Kenya KW - Sensitivity KW - Acquired immune deficiency syndrome KW - Data processing KW - Candidiasis KW - antiretroviral therapy KW - cotrimoxazole KW - Infection KW - Antiretroviral agents KW - Blood KW - Human immunodeficiency virus KW - Ulcers KW - Vagina KW - Prophylaxis KW - Trichomoniasis KW - Females KW - Sampling KW - Sexually transmitted diseases KW - Vaginosis KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1762377959?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+STD+%26+AIDS&rft.atitle=Genital+infections+and+syndromic+diagnosis+among+HIV-infected+women+in+HIV+care+programmes+in+Kenya&rft.au=Djomand%2C+Gaston%3BGao%2C+Hongjiang%3BSinga%2C+Benson%3BHornston%2C+Sureyya%3BBennett%2C+Eddas%3BOdek%2C+James%3BMcClelland%2C+R+Scott%3BJohn-Stewart%2C+Grace%3BBock%2C+Naomi&rft.aulast=Djomand&rft.aufirst=Gaston&rft.date=2016-01-01&rft.volume=27&rft.issue=1&rft.spage=19&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+STD+%26+AIDS&rft.issn=09564624&rft_id=info:doi/10.1177%2F0956462415568982 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Number of references - 21 N1 - Last updated - 2016-02-29 N1 - SubjectsTermNotLitGenreText - Blood; Data processing; Candidiasis; Ulcers; antiretroviral therapy; Vagina; Prophylaxis; Trichomoniasis; cotrimoxazole; Sampling; Infection; Vaginosis; Sensitivity; Acquired immune deficiency syndrome; Human immunodeficiency virus; Females; Antiretroviral agents; Sexually transmitted diseases; Kenya DO - http://dx.doi.org/10.1177/0956462415568982 ER - TY - JOUR T1 - The diagnosis and treatment of Helicobacter pylori infection in Arctic regions with a high prevalence of infection: Expert Commentary AN - 1751228696; PQ0002409315 AB - Helicobacter pylori infection is a major cause of peptic ulcer and is also associated with chronic gastritis, mucosa-associated lymphoid tissue (MALT) lymphoma, and adenocarcinoma of the stomach. Guidelines have been developed in the United States and Europe (areas with low prevalence) for the diagnosis and management of this infection, including the recommendation to 'test and treat' those with dyspepsia. A group of international experts performed a targeted literature review and formulated an expert opinion for evidenced-based benefits and harms for screening and treatment of H. pylori in high-prevalence countries. They concluded that in Arctic countries where H. pylori prevalence exceeds 60%, treatment of persons with H. pylori infection should be limited only to instances where there is strong evidence of direct benefit in reduction of morbidity and mortality, associated peptic ulcer disease and MALT lymphoma and that the test-and-treat strategy may not be beneficial for those with dyspepsia. JF - Epidemiology and Infection AU - McMAHON, B J AU - Bruce, M G AU - Koch, A AU - Goodman, K J AU - Tsukanov, V AU - Mulvad, G AU - Borresen, M L AU - Sacco, F AU - Barrett, D AU - Westby, S AU - Parkinson, A J AD - Departments of Internal Medicine and Surgery, Alaska Native Tribal Health Consortium, Anchorage, AK, USA, zwa8@cdc.gov Y1 - 2016/01// PY - 2016 DA - January 2016 SP - 225 EP - 233 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 144 IS - 2 SN - 0950-2688, 0950-2688 KW - Health & Safety Science Abstracts KW - PN, Arctic KW - Helicobacter pylori KW - Mortality KW - USA KW - Literature reviews KW - ANE, Europe KW - Guidelines KW - Infection KW - Polar environments KW - Lymphoma KW - Morbidity KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1751228696?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=The+diagnosis+and+treatment+of+Helicobacter+pylori+infection+in+Arctic+regions+with+a+high+prevalence+of+infection%3A+Expert+Commentary&rft.au=McMAHON%2C+B+J%3BBruce%2C+M+G%3BKoch%2C+A%3BGoodman%2C+K+J%3BTsukanov%2C+V%3BMulvad%2C+G%3BBorresen%2C+M+L%3BSacco%2C+F%3BBarrett%2C+D%3BWestby%2C+S%3BParkinson%2C+A+J&rft.aulast=McMAHON&rft.aufirst=B&rft.date=2016-01-01&rft.volume=144&rft.issue=2&rft.spage=225&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268815001181 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-12-01 N1 - Number of references - 52 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Mortality; Literature reviews; Guidelines; Polar environments; Infection; Lymphoma; Morbidity; Helicobacter pylori; PN, Arctic; USA; ANE, Europe DO - http://dx.doi.org/10.1017/S0950268815001181 ER - TY - JOUR T1 - Protection Against Rectal Chimeric Simian/Human Immunodeficiency Virus Transmission in Macaques by Rectal-Specific Gel Formulations of Maraviroc and Tenofovir AN - 1780527522; PQ0002879755 AB - Background. Rectal human immunodeficiency virus (HIV) transmission is an important driver of the HIV epidemic. Optimally formulated gels of antiretroviral drugs are under development for preventing rectally acquired HIV. We investigated in a macaque model the pharmacokinetics and efficacy of 3 rectal gel formulations Methods. Single-dose pharmacokinetics of low-osmolar 1% maraviroc (MVC), 1% tenofovir (TFV), or 1% MVC/1% TFV combination gel were evaluated in blood, rectal fluids, colorectal biopsy specimens, and rectal lymphocytes. Efficacy was evaluated over 10 twice-weekly rectal SHIV162p3 challenges in rhesus macaques that received either placebo (n = 7), MVC (n = 6), TFV (n = 6), or MVC/TFV (n = 6) gel 30 minutes before each challenge. Results. MVC and TFV were detected in plasma 30 minutes after gel application and remained above 95% inhibitory concentrations in rectal fluids at 24 hours. MVC, TFV, and TFV diphosphate (TFV-DP) concentrations in colorectal tissues collected up to 30 cm from the anal margin were all high at 2 hours, demonstrating rapid and extended tissue dosing. TFV-DP concentrations in tissue homogenates and rectal lymphocytes were highly correlated (r super(2) = 0.82). All 3 gel formulations were highly protective (82% efficacy; P [< or =] .02 by the log-rank test). Conclusions. Desirable pharmacokinetic profiles and high efficacy in this macaque model support the clinical development of these gel formulations for preventing rectal HIV infection. JF - Journal of Infectious Diseases AU - Dobard, Charles W AU - Taylor, Andrew AU - Sharma, Sunita AU - Anderson, Peter L AU - Bushman, Lane R AU - Chuong, Dinh AU - Pau, Chou-Pong AU - Hanson, Debra AU - Wang, Lin AU - Garcia-Lerma, J Gerardo AU - McGowan, Ian AU - Rohan, Lisa AU - Heneine, Walid AD - Laboratory Branch, Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, cdobard@cdc.gov Y1 - 2015/12/15/ PY - 2015 DA - 2015 Dec 15 SP - 1988 EP - 1995 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 212 IS - 12 SN - 0022-1899, 0022-1899 KW - Immunology Abstracts; Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - HIV prevention KW - rectal microbicides KW - maraviroc KW - tenofovir KW - macaque model KW - repeat-challenge KW - Rectum KW - Epidemics KW - Simian/human immunodeficiency virus KW - Biopsy KW - Drug development KW - Lymphocytes KW - Infection KW - Pharmacokinetics KW - Disease transmission KW - Gels KW - Blood KW - Infectious diseases KW - Antiviral agents KW - Human immunodeficiency virus KW - Macaca mulatta KW - V 22360:AIDS and HIV KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1780527522?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Protection+Against+Rectal+Chimeric+Simian%2FHuman+Immunodeficiency+Virus+Transmission+in+Macaques+by+Rectal-Specific+Gel+Formulations+of+Maraviroc+and+Tenofovir&rft.au=Dobard%2C+Charles+W%3BTaylor%2C+Andrew%3BSharma%2C+Sunita%3BAnderson%2C+Peter+L%3BBushman%2C+Lane+R%3BChuong%2C+Dinh%3BPau%2C+Chou-Pong%3BHanson%2C+Debra%3BWang%2C+Lin%3BGarcia-Lerma%2C+J+Gerardo%3BMcGowan%2C+Ian%3BRohan%2C+Lisa%3BHeneine%2C+Walid&rft.aulast=Dobard&rft.aufirst=Charles&rft.date=2015-12-15&rft.volume=212&rft.issue=12&rft.spage=1988&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiv334 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-04-01 N1 - Last updated - 2016-08-03 N1 - SubjectsTermNotLitGenreText - Gels; Blood; Epidemics; Rectum; Antiviral agents; Drug development; Biopsy; tenofovir; Lymphocytes; Infection; Pharmacokinetics; Disease transmission; Infectious diseases; Human immunodeficiency virus; Simian/human immunodeficiency virus; Macaca mulatta DO - http://dx.doi.org/10.1093/infdis/jiv334 ER - TY - JOUR T1 - Development and Characterization of Monoclonal Antibodies Directed Against the Nucleoprotein of Heartland Virus AN - 1787965786; PQ0002931889 AB - Heartland virus (HRTV), a phlebovirus first isolated from two Missouri farmers in 2009, has been proposed to be transmitted to humans by the bite of infected Amblyomma americanum ticks. It is closely related to severe fever with thrombocytopenia syndrome virus (SFTSV) from China, another previously unrecognized phlebovirus that has subsequently been associated with hundreds of cases of severe disease in humans. To expand diagnostic capacity to detect HRTV infections, 20 hybridoma clones secreting anti-HRTV murine monoclonal antibodies (MAbs) were developed using splenocytes from HRTV-inoculated AG129 alpha/beta and gamma interferon receptor-deficient mice. Nine of these MAbs were characterized herein for inclusion in future HRTV diagnostic assay development. All of the MAbs developed were found to be non-neutralizing and reactive to linear epitopes on HRTV nucleocapsid protein. MAb 2AF11 was found to be cross-reactive with SFTSV. JF - American Journal of Tropical Medicine and Hygiene AU - Calvert, Amanda E AU - Brault, Aaron C AD - Division of Vector-Borne Diseases, U.S. Centers for Disease Control and Prevention, Fort Collins, Colorado, zpz0@cdc.gov Y1 - 2015/12// PY - 2015 DA - December 2015 SP - 1338 EP - 1340 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 93 IS - 6 SN - 0002-9637, 0002-9637 KW - Entomology Abstracts; Virology & AIDS Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts KW - gamma -Interferon KW - Symptoms KW - Bites KW - Nucleoproteins KW - Infection KW - Disease transmission KW - Fever KW - Thrombocytopenia KW - Nucleocapsids KW - USA, Missouri KW - Epitopes KW - beta -Interferon KW - Heart KW - Clones KW - Monoclonal antibodies KW - Ixodidae KW - Mice KW - Phlebovirus KW - Amblyomma americanum KW - Hybridoma KW - Splenocytes KW - Proteins KW - China, People's Rep. KW - Hygiene KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - Q5 08524:Public health, medicines, dangerous organisms KW - V 22400:Human Diseases KW - K 03310:Genetics & Taxonomy KW - Q1 08204:Reproduction and development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1787965786?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=51st+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.atitle=Cryptococcal+Antigenemia+Among+Hospitalized%2C+HIVInfected+Patients+with+Acute+Respiratory+Infections+and+without+Meningitis+in+Thailand&rft.au=Harris%2C+J%3BLindsley%2C+M%3BHenchaichon%2C+S%3BPoonwan%2C+N%3BNaorat%2C+S%3BPrapasiri%2C+P%3BChantra%2C+S%3BChang%2C+L%3BPark%2C+B%3BBaggett%2C+H%3BChittaganpitch%2C+M%3BMekha%2C+N%3BMaloney%2C+S%3BRuamcharoen%2C+F&rft.aulast=Harris&rft.aufirst=J&rft.date=2011-09-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=51st+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-05-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Clones; Symptoms; Monoclonal antibodies; Hygiene; Disease transmission; Heart; beta -Interferon; gamma -Interferon; Bites; Nucleoproteins; Infection; Fever; Hybridoma; Splenocytes; Thrombocytopenia; Nucleocapsids; Epitopes; Proteins; Mice; Amblyomma americanum; Ixodidae; Phlebovirus; USA, Missouri; China, People's Rep. DO - http://dx.doi.org/10.4269/ajtmh.15-0473 ER - TY - JOUR T1 - 2013 multistate outbreaks of Cyclospora cayetanensis infections associated with fresh produce: focus on the Texas investigations AN - 1762382781; PQ0002459178 AB - The 2013 multistate outbreaks contributed to the largest annual number of reported US cases of cyclosporiasis since 1997. In this paper we focus on investigations in Texas. We defined an outbreak-associated case as laboratory-confirmed cyclosporiasis in a person with illness onset between 1 June and 31 August 2013, with no history of international travel in the previous 14 days. Epidemiological, environmental, and traceback investigations were conducted. Of the 631 cases reported in the multistate outbreaks, Texas reported the greatest number of cases, 270 (43%). More than 70 clusters were identified in Texas, four of which were further investigated. One restaurant-associated cluster of 25 case-patients was selected for a case-control study. Consumption of cilantro was most strongly associated with illness on meal date-matched analysis (matched odds ratio 19.8, 95% confidence interval 4.0- infinity ). All case-patients in the other three clusters investigated also ate cilantro. Traceback investigations converged on three suppliers in Puebla, Mexico. Cilantro was the vehicle of infection in the four clusters investigated; the temporal association of these clusters with the large overall increase in cyclosporiasis cases in Texas suggests cilantro was the vehicle of infection for many other cases. However, the paucity of epidemiological and traceback information does not allow for a conclusive determination; moreover, molecular epidemiological tools for cyclosporiasis that could provide more definitive linkage between case clusters are needed. JF - Epidemiology and Infection AU - ABANYIE, F AU - Harvey, R R AU - Harris, J R AU - Wiegand, R E AU - Gaul, L AU - desVignes-Kendrick, M AU - Irvin, K AU - Williams, I AU - Hall, R L AU - Herwaldt, B AU - Gray, E B AU - Qvarnstrom, Y AU - Wise, Me AU - Cantu, V AU - Cantey, P T AU - Bosch, S AU - da Silva, Aj AU - Fields, A AU - Bishop, H AU - Wellman, A AU - Beal, J AU - Wilson, N AU - Fiore, A E AU - Tauxe, R AU - Lance, S AU - SLUTSKER, L AU - Parise, M AD - Center for Global Health, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, GA, USA, why6@cdc.gov Y1 - 2015/12// PY - 2015 DA - December 2015 SP - 3451 EP - 3458 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 143 IS - 16 SN - 0950-2688, 0950-2688 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Health & Safety Science Abstracts KW - Travel KW - ASW, USA, Texas KW - Cyclospora cayetanensis KW - Historical account KW - Mexico KW - Outbreaks KW - Cyclosporiasis KW - Infection KW - K 03400:Human Diseases KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1762382781?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=2013+multistate+outbreaks+of+Cyclospora+cayetanensis+infections+associated+with+fresh+produce%3A+focus+on+the+Texas+investigations&rft.au=ABANYIE%2C+F%3BHarvey%2C+R+R%3BHarris%2C+J+R%3BWiegand%2C+R+E%3BGaul%2C+L%3BdesVignes-Kendrick%2C+M%3BIrvin%2C+K%3BWilliams%2C+I%3BHall%2C+R+L%3BHerwaldt%2C+B%3BGray%2C+E+B%3BQvarnstrom%2C+Y%3BWise%2C+Me%3BCantu%2C+V%3BCantey%2C+P+T%3BBosch%2C+S%3Bda+Silva%2C+Aj%3BFields%2C+A%3BBishop%2C+H%3BWellman%2C+A%3BBeal%2C+J%3BWilson%2C+N%3BFiore%2C+A+E%3BTauxe%2C+R%3BLance%2C+S%3BSLUTSKER%2C+L%3BParise%2C+M&rft.aulast=ABANYIE&rft.aufirst=F&rft.date=2015-12-01&rft.volume=143&rft.issue=16&rft.spage=3451&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268815000370 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Number of references - 12 N1 - Last updated - 2016-03-30 N1 - SubjectsTermNotLitGenreText - Travel; Cyclosporiasis; Infection; Historical account; Outbreaks; Cyclospora cayetanensis; ASW, USA, Texas; Mexico DO - http://dx.doi.org/10.1017/S0950268815000370 ER - TY - JOUR T1 - The East Jakarta Project: surveillance for highly pathogenic avian influenza A(H5N1) and seasonal influenza viruses in patients seeking care for respiratory disease, Jakarta, Indonesia, October 2011-September 2012 AN - 1762381400; PQ0002459173 AB - Indonesia has reported the most human infections with highly pathogenic avian influenza (HPAI) A(H5N1) virus worldwide. We implemented enhanced surveillance in four outpatient clinics and six hospitals for HPAI H5N1 and seasonal influenza viruses in East Jakarta district to assess the public health impact of influenza in Indonesia. Epidemiological and clinical data were collected from outpatients with influenza-like illness (ILI) and hospitalized patients with severe acute respiratory infection (SARI); respiratory specimens were obtained for influenza testing by real-time reverse transcription-polymerase chain reaction. During October 2011-September 2012, 1131/3278 specimens from ILI cases (34.5%) and 276/1787 specimens from SARI cases (15.4%) tested positive for seasonal influenza viruses. The prevalence of influenza virus infections was highest during December-May and the proportion testing positive was 76% for ILI and 36% for SARI during their respective weeks of peak activity. No HPAI H5N1 virus infections were identified, including hundreds of ILI and SARI patients with recent poultry exposures, whereas seasonal influenza was an important contributor to acute respiratory disease in East Jakarta. Overall, 668 (47%) of influenza viruses were influenza B, 384 (27%) were A(H1N1)pdm09, and 359 (25%) were H3. While additional data over multiple years are needed, our findings suggest that seasonal influenza prevention efforts, including influenza vaccination, should target the months preceding the rainy season. JF - Epidemiology and Infection AU - Storms, Ad AU - KUSRIASTUTI, R AU - MISRIYAH, S AU - PRAPTININGSIH, CY AU - AMALYA, M AU - Lafond, Ke AU - Samaan, G AU - TRIADA, R AU - Iuliano, Ad AU - Ester, M AU - SIDJABAT, R AU - Chittenden, K AU - Vogel, R AU - Widdowson, Ma AU - Mahoney, F AU - Uyeki, T M AD - Influenza Division. U.S. Centers for Disease Control and Prevention, Atlanta, GA, USA, tuyeki@cdc.gov Y1 - 2015/12// PY - 2015 DA - December 2015 SP - 3394 EP - 3404 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 143 IS - 16 SN - 0950-2688, 0950-2688 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Influenza B KW - Indonesia, Jawa, Jakarta KW - Poultry KW - Data processing KW - Viruses KW - Indonesia KW - Respiratory diseases KW - Infection KW - Vaccination KW - Public health KW - Influenza KW - Fowl plague KW - Prevention KW - Influenza virus KW - Sulfur dioxide KW - Rainy season KW - Vaccines KW - Seasonal variations KW - Hospitals KW - H 1000:Occupational Safety and Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1762381400?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=The+East+Jakarta+Project%3A+surveillance+for+highly+pathogenic+avian+influenza+A%28H5N1%29+and+seasonal+influenza+viruses+in+patients+seeking+care+for+respiratory+disease%2C+Jakarta%2C+Indonesia%2C+October+2011-September+2012&rft.au=Storms%2C+Ad%3BKUSRIASTUTI%2C+R%3BMISRIYAH%2C+S%3BPRAPTININGSIH%2C+CY%3BAMALYA%2C+M%3BLafond%2C+Ke%3BSamaan%2C+G%3BTRIADA%2C+R%3BIuliano%2C+Ad%3BEster%2C+M%3BSIDJABAT%2C+R%3BChittenden%2C+K%3BVogel%2C+R%3BWiddowson%2C+Ma%3BMahoney%2C+F%3BUyeki%2C+T+M&rft.aulast=Storms&rft.aufirst=Ad&rft.date=2015-12-01&rft.volume=143&rft.issue=16&rft.spage=3394&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Number of references - 28 N1 - Last updated - 2016-03-30 N1 - SubjectsTermNotLitGenreText - Influenza B; Fowl plague; Poultry; Data processing; Infection; Vaccination; Hospitals; Public health; Influenza; Prevention; Rainy season; Sulfur dioxide; Viruses; Vaccines; Respiratory diseases; Seasonal variations; Influenza virus; Indonesia, Jawa, Jakarta; Indonesia DO - http://dx.doi.org/10.1017/S0950268815000771 ER - TY - JOUR T1 - Climate Change in the North American Arctic: A One Health Perspective. AN - 1754083965; 26070525 AB - Climate change is expected to increase the prevalence of acute and chronic diseases among human and animal populations within the Arctic and subarctic latitudes of North America. Warmer temperatures are expected to increase disease risks from food-borne pathogens, water-borne diseases, and vector-borne zoonoses in human and animal populations of Arctic landscapes. Existing high levels of mercury and persistent organic pollutant chemicals circulating within terrestrial and aquatic ecosystems in Arctic latitudes are a major concern for the reproductive health of humans and other mammals, and climate warming will accelerate the mobilization and biological amplification of toxic environmental contaminants. The adverse health impacts of Arctic warming will be especially important for wildlife populations and indigenous peoples dependent upon subsistence food resources from wild plants and animals. Additional research is needed to identify and monitor changes in the prevalence of zoonotic pathogens in humans, domestic dogs, and wildlife species of critical subsistence, cultural, and economic importance to Arctic peoples. The long-term effects of climate warming in the Arctic cannot be adequately predicted or mitigated without a comprehensive understanding of the interactive and synergistic effects between environmental contaminants and pathogens in the health of wildlife and human communities in Arctic ecosystems. The complexity and magnitude of the documented impacts of climate change on Arctic ecosystems, and the intimacy of connections between their human and wildlife communities, makes this region an appropriate area for development of One Health approaches to identify and mitigate the effects of climate warming at the community, ecosystem, and landscape scales. JF - EcoHealth AU - Dudley, Joseph P AU - Hoberg, Eric P AU - Jenkins, Emily J AU - Parkinson, Alan J AD - Leidos, Inc., 20201 Century Boulevard, Suite 105, Germantown, MD, 20874, USA. jpdudley@alaska.edu. ; US National Parasite Collection, U.S. Department of Agriculture - Agricultural Research Service, Beltsville, MD, 20705, USA. Eric.Hoberg@ARS.USDA.GOV. ; Department of Veterinary Microbiology, University of Saskatchewan, Saskatoon, SK, S7N 5B4, Canada. ejj266@mail.usask.ca. ; Arctic Investigations Program, Division of Preparedness and Emerging Infections, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Anchorage, AK, 99508, USA. parkinsonalanj@gmail.com. Y1 - 2015/12// PY - 2015 DA - December 2015 SP - 713 EP - 725 VL - 12 IS - 4 KW - Index Medicus KW - cultural resilience KW - parasites KW - wildlife diseases KW - environmental pollutants KW - zoonosis KW - indigenous peoples KW - One Health KW - climate change KW - Environmental Monitoring KW - Ecosystem KW - Arctic Regions -- epidemiology KW - Animals KW - Population Groups KW - Indians, North American KW - North America -- epidemiology KW - Humans KW - Animals, Wild KW - Acute Disease -- epidemiology KW - Foodborne Diseases -- epidemiology KW - Waterborne Diseases -- epidemiology KW - Climate Change KW - Chronic Disease -- epidemiology KW - Zoonoses -- epidemiology KW - Environmental Pollution -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1754083965?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=EcoHealth&rft.atitle=Climate+Change+in+the+North+American+Arctic%3A+A+One+Health+Perspective.&rft.au=Dudley%2C+Joseph+P%3BHoberg%2C+Eric+P%3BJenkins%2C+Emily+J%3BParkinson%2C+Alan+J&rft.aulast=Dudley&rft.aufirst=Joseph&rft.date=2015-12-01&rft.volume=12&rft.issue=4&rft.spage=713&rft.isbn=&rft.btitle=&rft.title=EcoHealth&rft.issn=1612-9210&rft_id=info:doi/10.1007%2Fs10393-015-1036-1 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2016-10-11 N1 - Date created - 2016-01-05 N1 - Date revised - 2017-01-14 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1007/s10393-015-1036-1 ER - TY - JOUR T1 - Life Expectancy after Inpatient Rehabilitation for Traumatic Brain Injury in the United States. AN - 1744663672; 25057965 AB - This study characterized life expectancy after traumatic brain injury (TBI). The TBI Model Systems (TBIMS) National Database (NDB) was weighted to represent those ≥16 years of age completing inpatient rehabilitation for TBI in the United States (US) between 2001 and 2010. Analyses included Standardized Mortality Ratios (SMRs), Cox regression, and life expectancy. The US mortality rates by age, sex, race, and cause of death for 2005 and 2010 were used for comparison purposes. Results indicated that a total of 1325 deaths occurred in the weighted cohort of 6913 individuals. Individuals with TBI were 2.23 times more likely to die than individuals of comparable age, sex, and race in the general population, with a reduced average life expectancy of 9 years. Independent risk factors for death were: older age, male gender, less-than-high school education, previously married at injury, not employed at injury, more recent year of injury, fall-related TBI, not discharged home after rehabilitation, less functional independence, and greater disability. Individuals with TBI were at greatest risk of death from seizures; accidental poisonings; sepsis; aspiration pneumonia; respiratory, mental/behavioral, or nervous system conditions; and other external causes of injury and poisoning, compared with individuals in the general population of similar age, gender, and race. This study confirms prior life expectancy study findings, and provides evidence that the TBIMS NDB is representative of the larger population of adults receiving inpatient rehabilitation for TBI in the US. There is an increased risk of death for individuals with TBI requiring inpatient rehabilitation. JF - Journal of neurotrauma AU - Harrison-Felix, Cynthia AU - Pretz, Christopher AU - Hammond, Flora M AU - Cuthbert, Jeffrey P AU - Bell, Jeneita AU - Corrigan, John AU - Miller, A Cate AU - Haarbauer-Krupa, Juliet AD - 1 Research Department, Craig Hospital , Englewood, Colorado. ; 2 Rehabilitation Hospital of Indiana , Indianapolis, India na. ; 3 Traumatic Brain Injury Team, Health Systems and Trauma Systems Branch, Division of Unintentional Injury Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention , Altanta, Georgia . ; 4 Department of Physical Medicine and Rehabilitation, Ohio State University , Columbus, Ohio. ; 5 National Institute on Disability and Rehabilitation Research , United States Department of Education, Washington, DC. Y1 - 2015/12/01/ PY - 2015 DA - 2015 Dec 01 SP - 1893 EP - 1901 VL - 32 IS - 23 KW - Index Medicus KW - mortality KW - rehabilitation KW - life expectancy KW - brain injury, chronic KW - Young Adult KW - Risk Factors KW - Humans KW - Adult KW - Databases, Factual KW - Aged KW - Middle Aged KW - Inpatients KW - Adolescent KW - United States -- epidemiology KW - Male KW - Female KW - Cause of Death KW - Brain Injuries -- rehabilitation KW - Life Expectancy KW - Brain Injuries -- mortality UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1744663672?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+neurotrauma&rft.atitle=Life+Expectancy+after+Inpatient+Rehabilitation+for+Traumatic+Brain+Injury+in+the+United+States.&rft.au=Harrison-Felix%2C+Cynthia%3BPretz%2C+Christopher%3BHammond%2C+Flora+M%3BCuthbert%2C+Jeffrey+P%3BBell%2C+Jeneita%3BCorrigan%2C+John%3BMiller%2C+A+Cate%3BHaarbauer-Krupa%2C+Juliet&rft.aulast=Harrison-Felix&rft.aufirst=Cynthia&rft.date=2015-12-01&rft.volume=32&rft.issue=23&rft.spage=1893&rft.isbn=&rft.btitle=&rft.title=Journal+of+neurotrauma&rft.issn=1557-9042&rft_id=info:doi/10.1089%2Fneu.2014.3353 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2016-09-14 N1 - Date created - 2015-12-03 N1 - Date revised - 2017-01-14 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1089/neu.2014.3353 ER - TY - JOUR T1 - Comparison of Methods for Xenomonitoring in Vectors of Lymphatic Filariasis in Northeastern Tanzania AN - 1765944004; PQ0002617748 AB - Monitoring Wuchereria bancrofti infection in mosquitoes (xenomonitoring) can play an important role in determining when lymphatic filariasis has been eliminated, or in focusing control efforts. As mosquito infection rates can be low, a method for collecting large numbers of mosquitoes is necessary. Gravid traps collected large numbers of Culex quinquefasciatus in Tanzania, and a collection method that targets mosquitoes that have already fed could result in increased sensitivity in detecting W. bancrofti-infected mosquitoes. The aim of this experiment was to test this hypothesis by comparing U.S. Centers for Disease Control and Prevention (CDC) light traps with CDC gravid traps in northeastern Tanzania, where Cx. quinquefasciatus is a vector of lymphatic filariasis. After an initial study where small numbers of mosquitoes were collected, a second study collected 16,316 Cx. quinquefasciatus in 60 gravid trap-nights and 240 light trap-nights. Mosquitoes were pooled and tested for presence of W. bancrofti DNA. Light and gravid traps collected similar numbers of mosquitoes per trap-night, but the physiological status of the mosquitoes was different. The estimated infection rate in mosquitoes collected in light traps was considerably higher than in mosquitoes collected in gravid traps, so light traps can be a useful tool for xenomonitoring work in Tanzania. JF - American Journal of Tropical Medicine and Hygiene AU - Irish, Seth R AU - Stevens, William M B AU - Derua, Yahya A AU - Walker, Thomas AU - Cameron, Mary M AD - London School of Hygiene and Tropical Medicine, London, United Kingdom, sirish@cdc.gov Y1 - 2015/11// PY - 2015 DA - November 2015 SP - 983 EP - 989 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 93 IS - 5 SN - 0002-9637, 0002-9637 KW - Entomology Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts KW - Physiology KW - Filariasis KW - Disease control KW - Hosts KW - Infection KW - Disease transmission KW - Aquatic insects KW - Culex quinquefasciatus KW - Sensitivity KW - Light traps KW - Vectors KW - Pest control KW - ISW, Tanzania KW - Light effects KW - Methodology KW - Prevention KW - Wuchereria bancrofti KW - DNA KW - Hygiene KW - K 03410:Animal Diseases KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - Q1 08485:Species interactions: pests and control KW - Q5 08524:Public health, medicines, dangerous organisms KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1765944004?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Comparison+of+Methods+for+Xenomonitoring+in+Vectors+of+Lymphatic+Filariasis+in+Northeastern+Tanzania&rft.au=Irish%2C+Seth+R%3BStevens%2C+William+M+B%3BDerua%2C+Yahya+A%3BWalker%2C+Thomas%3BCameron%2C+Mary+M&rft.aulast=Irish&rft.aufirst=Seth&rft.date=2015-11-01&rft.volume=93&rft.issue=5&rft.spage=983&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.15-0234 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Disease control; DNA; Pest control; Hosts; Hygiene; Aquatic insects; Methodology; Disease transmission; Light traps; Filariasis; Vectors; Infection; Light effects; Sensitivity; Prevention; Physiology; Culex quinquefasciatus; Wuchereria bancrofti; ISW, Tanzania DO - http://dx.doi.org/10.4269/ajtmh.15-0234 ER - TY - JOUR T1 - Nationwide outbreak of multidrug-resistant Salmonella Heidelberg infections associated with ground turkey: United States, 2011 AN - 1762382524; PQ0002459153 AB - On 23 May 2011, CDC identified a multistate cluster of Salmonella Heidelberg infections and two multidrug-resistant (MDR) isolates from ground turkey retail samples with indistinguishable pulsed-field gel electrophoresis patterns. We defined cases as isolation of outbreak strains in persons with illness onset between 27 February 2011 and 10 November 2011. Investigators collected hypothesis-generating questionnaires and shopper-card information. Food samples from homes and retail outlets were collected and cultured. We identified 136 cases of S. Heidelberg infection in 34 states. Shopper-card information, leftover ground turkey from a patient's home containing the outbreak strain and identical antimicrobial resistance profiles of clinical and retail samples pointed to plant A as the source. On 3 August, plant A recalled 36 million pounds of ground turkey. This outbreak increased consumer interest in MDR Salmonella infections acquired through United States-produced poultry and played a vital role in strengthening food safety policies related to Salmonella and raw ground poultry. JF - Epidemiology and Infection AU - Routh, Ja AU - Pringle, J AU - Mohr, M AU - BIDOL, S AU - Arends, K AU - Adams-Cameron, M AU - Hancock, W T AU - Kissler, B AU - Rickert, R AU - FOLSTER, J AU - Tolar, B AU - Bosch, S AU - BARTON BEHRAVESH, C AU - Williams, I T AU - GIERALTOWSKI, L AD - Outbreak Response and Prevention Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA, iyp1@cdc.gov Y1 - 2015/11// PY - 2015 DA - November 2015 SP - 3227 EP - 3234 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 143 IS - 15 SN - 0950-2688, 0950-2688 KW - Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts KW - Inventories KW - Poultry KW - Electrophoresis KW - Drug resistance KW - Food KW - Food contamination KW - Infection KW - Antimicrobial agents KW - USA KW - Pulsed-field gel electrophoresis KW - Consumers KW - Outbreaks KW - Salmonella KW - J 02400:Human Diseases KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1762382524?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Nationwide+outbreak+of+multidrug-resistant+Salmonella+Heidelberg+infections+associated+with+ground+turkey%3A+United+States%2C+2011&rft.au=Routh%2C+Ja%3BPringle%2C+J%3BMohr%2C+M%3BBIDOL%2C+S%3BArends%2C+K%3BAdams-Cameron%2C+M%3BHancock%2C+W+T%3BKissler%2C+B%3BRickert%2C+R%3BFOLSTER%2C+J%3BTolar%2C+B%3BBosch%2C+S%3BBARTON+BEHRAVESH%2C+C%3BWilliams%2C+I+T%3BGIERALTOWSKI%2C+L&rft.aulast=Orata&rft.aufirst=Fabini&rft.date=2015-10-09&rft.volume=7&rft.issue=10&rft.spage=2941&rft.isbn=&rft.btitle=&rft.title=Genome+biology+and+evolution&rft.issn=1759-6653&rft_id=info:doi/10.1093%2Fgbe%2Fevv193 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Number of references - 15 N1 - Last updated - 2016-03-30 N1 - SubjectsTermNotLitGenreText - Inventories; Poultry; Food; Drug resistance; Pulsed-field gel electrophoresis; Consumers; Infection; Electrophoresis; Outbreaks; Food contamination; Antimicrobial agents; Salmonella; USA DO - http://dx.doi.org/10.1017/S0950268815000497 ER - TY - JOUR T1 - Bias from Differential Exposure Measurement Error in a Study of Flight Attendants AN - 1762365043; PQ0002504350 AB - BACKGROUND: Self-reported occupational exposures are often used in epidemiological studies when actual exposure measurements are unavailable, which could cause measurement error and bias study results. This study provides a numeric example of this potential bias. METHODS: A study of block hours and preterm birth was used as an illustrative example. This study included 577 flight attendants, ages 18-45 yr, who gave birth to a term (37 or greater gestational weeks) or preterm (20-36 gestational weeks) infant between 1992 and 1996. Flight attendants self-reported the number of block hours flown during the first trimester of pregnancy; the number of block hours flown during the first trimester of pregnancy was also calculated from airline records. No adjustment for confounding was performed for this illustrative example. RESULTS: Although flight attendants having term and preterm births self-reported similar hours worked during the first trimester (median 213 vs. 215 block hours), airline records showed that flight attendants having term births worked more hours than those having preterm births (median 146 vs. 104 block hours). Using self-reported block hours, there was no association between block hours and preterm birth; when using airline records, an inverse association was observed. DISCUSSION: In this example, differential measurement error from use of self-reported block hours obscured an inverse association apparent when using airline records, demonstrating the importance of accurate exposure assessment for identifying occupational risk factors for health outcomes. JF - Aerospace Medicine and Human Performance AU - Johnson, Candice Y AU - Grajewski, Barbara AD - National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, 1090 Tusculum Ave., MS R-15, Cincinnati, OH 45226, cyjohnson@cdc.gov Y1 - 2015/11// PY - 2015 DA - November 2015 SP - 990 EP - 993 PB - Aerospace Medical Association, 320 S. Henry St. Alexandria VA 22314-3579 United States VL - 86 IS - 11 SN - 2375-6314, 2375-6314 KW - Health & Safety Science Abstracts KW - block hours KW - exposure assessment KW - preterm birth KW - Age KW - Risk factors KW - Airlines KW - Human factors KW - Occupational exposure KW - Pregnancy KW - Infants KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1762365043?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aerospace+Medicine+and+Human+Performance&rft.atitle=Bias+from+Differential+Exposure+Measurement+Error+in+a+Study+of+Flight+Attendants&rft.au=Johnson%2C+Candice+Y%3BGrajewski%2C+Barbara&rft.aulast=Johnson&rft.aufirst=Candice&rft.date=2015-11-01&rft.volume=86&rft.issue=11&rft.spage=990&rft.isbn=&rft.btitle=&rft.title=Aerospace+Medicine+and+Human+Performance&rft.issn=23756314&rft_id=info:doi/10.3357%2FAMHP.4321.2015 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Number of references - 6 N1 - Last updated - 2016-02-29 N1 - SubjectsTermNotLitGenreText - Age; Risk factors; Airlines; Human factors; Occupational exposure; Infants; Pregnancy DO - http://dx.doi.org/10.3357/AMHP.4321.2015 ER - TY - JOUR T1 - Nocardia arizonensis sp. nov., obtained from human respiratory specimens AN - 1746880922; PQ0002184690 AB - In 2008, three clinical isolates (W9405 super(T), W9409 and W9575) were obtained from bronchial wash or sputum specimens from patients from the state of Arizona and characterised by polyphasic analysis. All three clinical isolates 16S rRNA gene sequences were found to be 100 % identical to each other and showed the strains belong in the genus Nocardia. BLASTn searches in the GenBank database of near full-length 16S rRNA gene sequences showed the highest sequence similarities to the type strains of Nocardia takedensis (98.3 %, sequence similarity), Nocardia lijiangensis (97.4 %), Nocardia harenae (97.4 %), and Nocardia xishanensis (97.1 %). The DNA-DNA relatedness between isolate W9405 super(T) and the type strain of N. takedensis is 26.0 plus or minus 2.4 % when measured in silico using genomic DNA sequences. The G+C content of isolate W9405 super(T) is 68.6 mol%. Chemotaxonomic analyses of the clinical isolates were consistent with their assignment to the genus Nocardia: whole cell hydrolysates contain meso-diaminopimelic acid as the diagnostic diamino acid of peptidoglycan; the whole-cell sugars are arabinose and galactose; the predominant phospholipids include diphosphatidylglycerol, phosphatidylethanolamine and phosphatidylinositol; MK-8-(H sub(4)) omega -cyc as the major menaquinone; mycolic acids ranging from 38 to 62 carbon atoms; and palmitic acid, tuberculostearic acid, palmitelaidic acid and oleic acid are the major fatty acids. Genus and species specific profiles were obtained following analysis by matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectra of the clinical isolates. All isolates were found to be intermediately resistant or resistant to minocycline and resistant to ciprofloxacin but were susceptible to amikacin, imipenem and linezolid. Our polyphasic analysis suggest the three clinical isolates obtained from patients in Arizona represent a novel species of Nocardia for which we propose the name Nocardia arizonensis, with strain W9405 super(T) (=DSM 45748 super(T) = CCUG 62754 super(T) = NBRC 108935 super(T)) as the type strain. JF - Antonie Van Leeuwenhoek AU - Lasker, Brent A AU - Bell, Melissa AU - Klenk, Hans-Peter AU - Schumann, Peter AU - Brown, June M AD - Centers for Disease Control and Prevention, Building 17, Room 2025, Mailstop G-11, 1600 Clifton Road, Atlanta, GA, 30333, USA, blasker@cdc.gov Y1 - 2015/11// PY - 2015 DA - November 2015 SP - 1129 EP - 1137 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 108 IS - 5 SN - 0003-6072, 0003-6072 KW - Microbiology Abstracts B: Bacteriology KW - Galactose KW - Minocycline KW - Amikacin KW - phosphatidylinositol KW - Diphosphatidylglycerol KW - Nucleotide sequence KW - peptidoglycans KW - Mycolic acids KW - Flight KW - Ciprofloxacin KW - Carbon KW - genomics KW - Nocardia KW - Linezolid KW - Hydrolysates KW - Phospholipids KW - Clinical isolates KW - Sugar KW - Imipenem KW - Databases KW - Menaquinones KW - Palmitic acid KW - Fatty acids KW - Arabinose KW - Lasers KW - phosphatidylethanolamine KW - Sputum KW - Oleic acid KW - rRNA 16S KW - New species KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1746880922?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antonie+Van+Leeuwenhoek&rft.atitle=Nocardia+arizonensis+sp.+nov.%2C+obtained+from+human+respiratory+specimens&rft.au=Lasker%2C+Brent+A%3BBell%2C+Melissa%3BKlenk%2C+Hans-Peter%3BSchumann%2C+Peter%3BBrown%2C+June+M&rft.aulast=Lasker&rft.aufirst=Brent&rft.date=2015-11-01&rft.volume=108&rft.issue=5&rft.spage=1129&rft.isbn=&rft.btitle=&rft.title=Antonie+Van+Leeuwenhoek&rft.issn=00036072&rft_id=info:doi/10.1007%2Fs10482-015-0566-4 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-12-01 N1 - Last updated - 2016-08-03 N1 - SubjectsTermNotLitGenreText - Galactose; Minocycline; Amikacin; phosphatidylinositol; Nucleotide sequence; Diphosphatidylglycerol; peptidoglycans; Mycolic acids; Flight; Ciprofloxacin; Carbon; genomics; Linezolid; Hydrolysates; Phospholipids; Clinical isolates; Sugar; Imipenem; Databases; Menaquinones; Palmitic acid; Arabinose; Fatty acids; Lasers; Sputum; phosphatidylethanolamine; rRNA 16S; Oleic acid; New species; Nocardia DO - http://dx.doi.org/10.1007/s10482-015-0566-4 ER - TY - JOUR T1 - Electron Microscopic Analysis of Surface Inorganic Substances on Oral and Combustible Tobacco Products. AN - 1728674089; 26286581 AB - Although quantitative trace toxic metal analyses have been performed on tobacco products, little has been published on inorganic particulate constituents on and inside the products. We analyzed these constituents using scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM-EDS). The nature of SEM-EDS instrumentation makes it an ideal choice for inorganic particulate analyses and yields relevant information to potential exposures during consumption of oral tobacco products, and possibly as a consequence of smoking. Aluminum silicates, silica and calcium compounds were common inorganic particulate constituents of tobacco products. Aluminum silicates and silica from soil were found on external leaf surfaces. Phytolithic silica, found in the lumen of the plant leaf, is of biogenic origin. Calcium oxalate was also apparently of biogenic origin. Small mineral deposits on tobacco could have health implications. Minerals found on the surfaces of smokeless tobacco products could possibly abrade the oral mucosa and contribute to the oral inflammatory responses observed with smokeless tobacco product use. If micron and sub-micron size calcium particles on cigarette filler were transported in mainstream smoke, they could potentially induce a pulmonary irritant inflammation when inhaled. The transport of aluminum silicate and silica in smoke could potentially also contribute to chronic inflammatory disease. Published by Oxford University Press 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US. JF - Journal of analytical toxicology AU - Halstead, Mary M AU - Watson, Clifford H AU - Pappas, R Steven AD - Battelle Analytical Services, Atlanta, GA, USA. ; Centers for Disease Control and Prevention, Atlanta, GA, USA. ; Centers for Disease Control and Prevention, Atlanta, GA, USA RPappas@cdc.gov. PY - 2015 SP - 698 EP - 701 VL - 39 IS - 9 KW - Aluminum Silicates KW - 0 KW - Silicon Dioxide KW - 7631-86-9 KW - Calcium KW - SY7Q814VUP KW - Index Medicus KW - Administration, Oral KW - Silicon Dioxide -- analysis KW - X-Ray Absorption Spectroscopy KW - Particle Size KW - Calcium -- analysis KW - Aluminum Silicates -- analysis KW - Plant Leaves -- chemistry KW - Tobacco -- chemistry KW - Tobacco Products -- analysis KW - Microscopy, Electron, Scanning UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1728674089?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+analytical+toxicology&rft.atitle=Electron+Microscopic+Analysis+of+Surface+Inorganic+Substances+on+Oral+and+Combustible+Tobacco+Products.&rft.au=Halstead%2C+Mary+M%3BWatson%2C+Clifford+H%3BPappas%2C+R+Steven&rft.aulast=Halstead&rft.aufirst=Mary&rft.date=2015-11-01&rft.volume=39&rft.issue=9&rft.spage=698&rft.isbn=&rft.btitle=&rft.title=Journal+of+analytical+toxicology&rft.issn=1945-2403&rft_id=info:doi/10.1093%2Fjat%2Fbkv097 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2016-08-30 N1 - Date created - 2015-10-31 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Cited By: Chemistry. 2001 May 4;7(9):1881-8 [11405466] Tob Control. 2003 Dec;12(4):424-30 [14660781] Lab Invest. 1975 Feb;32(2):125-32 [163418] MMWR Morb Mortal Wkly Rep. 2014 May 2;63(17):369-74 [24785982] J Am Dent Assoc. 1990 Jul;121(1):117-23 [2370378] J Oral Pathol Med. 1994 Apr;23(4):161-7 [8046653] J Periodontol. 1998 Jun;69(6):620-31 [9660330] Food Chem Toxicol. 2006 May;44(5):714-23 [16309811] Plant Physiol. 2006 May;141(1):188-95 [16514014] Food Chem Toxicol. 2007 Feb;45(2):202-9 [17011104] Tob Control. 2007 Feb;16(1):8-14 [17297067] Contact Dermatitis. 2007 Jul;57(1):40-3 [17577356] IARC Monogr Eval Carcinog Risks Hum. 2007;89:1-592 [18335640] J Anal Toxicol. 2008 May;32(4):281-91 [18430295] J Anal Toxicol. 2014 May;38(4):204-11 [24535337] J Anal Toxicol. 2013 Jun;37(5):298-304 [23548667] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1093/jat/bkv097 ER - TY - CPAPER T1 - Evaluating the CDCs Prevention Research Centers Network: A Model for Stakeholder-oriented Evaluation Planning T2 - 143rd American Public Health Association Annual Meeting and Exposition (APHA 2015) AN - 1731764674; 6367727 JF - 143rd American Public Health Association Annual Meeting and Exposition (APHA 2015) AU - Lilleston, Pam AU - Bish, Connie AU - Mehran, Massoudi Y1 - 2015/10/31/ PY - 2015 DA - 2015 Oct 31 KW - Prevention KW - Models UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1731764674?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=143rd+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2015%29&rft.atitle=Evaluating+the+CDCs+Prevention+Research+Centers+Network%3A+A+Model+for+Stakeholder-oriented+Evaluation+Planning&rft.au=Lilleston%2C+Pam%3BBish%2C+Connie%3BMehran%2C+Massoudi&rft.aulast=Lilleston&rft.aufirst=Pam&rft.date=2015-10-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=143rd+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2015%29&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/143am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-11-06 N1 - Last updated - 2015-11-09 ER - TY - JOUR T1 - Detection of the HA-33 protein in botulinum neurotoxin type G complex by mass spectrometry. AN - 1727652434; 26494251 AB - The disease botulism is caused by intoxication with botulinum neurotoxins (BoNTs), extremely toxic proteins which cause paralysis. This neurotoxin is produced by some members of the Clostridium botulinum and closely related species, and is produced as a protein complex consisting of the neurotoxin and neurotoxin-associated proteins (NAPs). There are seven known serotypes of BoNT, A-G, and the composition of the NAPs can differ between these serotypes. It was previously published that the BoNT/G complex consisted of BoNT/G, nontoxic-nonhemagglutinin (NTNH), Hemagglutinin 70 (HA-70), and HA-17, but that HA-33, a component of the protein complex of other serotypes of BoNT, was not found. Components of the BoNT/G complex were first separated by SDS-PAGE, and bands corresponding to components of the complex were digested and analyzed by LC-MS/MS. Gel bands were identified with sequence coverages of 91% for BoNT/G, 91% for NTNH, 89% for HA-70, and 88% for HA-17. Notably, one gel band was also clearly identified as HA-33 with 93% sequence coverage. The BoNT/G complex consists of BoNT/G, NTNH, HA-70, HA-17, and HA-33. These proteins form the progenitor form of BoNT/G, similar to all other HA positive progenitor toxin complexes. JF - BMC microbiology AU - Kalb, Suzanne R AU - Baudys, Jakub AU - Barr, John R AD - Centers for Disease Control and Prevention, National Center for Environmental Health, Division of Laboratory Sciences, 4770 Buford Hwy, NE, Atlanta, GA, 30341, USA. skalb@cdc.gov. ; Centers for Disease Control and Prevention, National Center for Environmental Health, Division of Laboratory Sciences, 4770 Buford Hwy, NE, Atlanta, GA, 30341, USA. jbaudys@cdc.gov. ; Centers for Disease Control and Prevention, National Center for Environmental Health, Division of Laboratory Sciences, 4770 Buford Hwy, NE, Atlanta, GA, 30341, USA. jbarr@cdc.gov. Y1 - 2015/10/23/ PY - 2015 DA - 2015 Oct 23 SP - 227 VL - 15 KW - botulinum toxin type G KW - 0 KW - hemagglutinin 33 protein, Clostridium botulinum KW - Botulinum Toxins KW - EC 3.4.24.69 KW - Index Medicus KW - Electrophoresis, Polyacrylamide Gel KW - Chromatography, Liquid KW - Tandem Mass Spectrometry KW - Botulinum Toxins -- analysis KW - Clostridium botulinum -- metabolism KW - Botulinum Toxins -- chemistry KW - Botulinum Toxins -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727652434?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=BMC+microbiology&rft.atitle=Detection+of+the+HA-33+protein+in+botulinum+neurotoxin+type+G+complex+by+mass+spectrometry.&rft.au=Kalb%2C+Suzanne+R%3BBaudys%2C+Jakub%3BBarr%2C+John+R&rft.aulast=Kalb&rft.aufirst=Suzanne&rft.date=2015-10-23&rft.volume=15&rft.issue=&rft.spage=227&rft.isbn=&rft.btitle=&rft.title=BMC+microbiology&rft.issn=1471-2180&rft_id=info:doi/10.1186%2Fs12866-015-0567-5 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2016-06-28 N1 - Date created - 2015-10-23 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Cited By: Infect Immun. 1996 May;64(5):1589-94 [8613365] FEBS Lett. 1993 Nov 29;335(1):99-103 [8243676] Curr Microbiol. 1997 Oct;35(4):207-14 [9290060] Appl Environ Microbiol. 2005 Aug;71(8):4478-86 [16085839] Microbiology. 2005 Nov;151(Pt 11):3739-47 [16272395] Appl Environ Microbiol. 2010 Jan;76(1):40-7 [19915042] Toxicon. 2011 Jul;58(1):62-7 [21600236] BMC Microbiol. 2011;11:232 [22008244] J Biol Chem. 1994 Jan 21;269(3):1617-20 [8294407] J Biol Chem. 1994 Apr 29;269(17):12764-72 [8175689] Biochem Biophys Res Commun. 1994 Apr 29;200(2):829-35 [7910017] J Biol Chem. 1994 Aug 12;269(32):20213-6 [8051110] Infect Immun. 1995 May;63(5):2087-91 [7729925] J Biol Chem. 1995 May 5;270(18):10566-70 [7737992] J Biol Chem. 1996 Mar 29;271(13):7694-9 [8631808] FEBS Lett. 2012 Jan 20;586(2):109-15 [22172278] J Clin Microbiol. 2012 Dec;50(12):4091-4 [22993181] PLoS Pathog. 2013;9(10):e1003690 [24130488] Anal Chem. 2014 Apr 1;86(7):3254-62 [24605815] Appl Environ Microbiol. 2015 Jan;81(2):481-91 [25362065] Infect Genet Evol. 2015 Mar;30:102-13 [25489752] FEBS Lett. 2000 Feb 11;467(2-3):179-83 [10675534] J Protein Chem. 1999 Oct;18(7):753-60 [10691185] Infect Immun. 1977 Jun;16(3):910-4 [19355] FEMS Microbiol Lett. 1991 Apr 15;63(2-3):165-70 [1905655] Nature. 1992 Oct 29;359(6398):832-5 [1331807] J Biol Chem. 1993 Jun 5;268(16):11516-9 [8505288] Nature. 1993 Sep 9;365(6442):160-3 [8103915] EMBO J. 1993 Dec;12(12):4821-8 [7901002] J Biol Chem. 1993 Nov 15;268(32):23784-7 [8226912] Biochemistry. 1996 Feb 27;35(8):2630-6 [8611567] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1186/s12866-015-0567-5 ER - TY - JOUR T1 - The Dynamics of Genetic Interactions between Vibrio metoecus and Vibrio cholerae, Two Close Relatives Co-Occurring in the Environment. AN - 1728671782; 26454015 AB - Vibrio metoecus is the closest relative of Vibrio cholerae, the causative agent of the potent diarrheal disease cholera. Although the pathogenic potential of this new species is yet to be studied in depth, it has been co-isolated with V. cholerae in coastal waters and found in clinical specimens in the United States. We used these two organisms to investigate the genetic interaction between closely related species in their natural environment. The genomes of 20 V. cholerae and 4 V. metoecus strains isolated from a brackish coastal pond on the US east coast, as well as 4 clinical V. metoecus strains were sequenced and compared with reference strains. Whole genome comparison shows 86-87% average nucleotide identity (ANI) in their core genes between the two species. On the other hand, the chromosomal integron, which occupies approximately 3% of their genomes, shows higher conservation in ANI between species than any other region of their genomes. The ANI of 93-94% observed in this region is not significantly greater within than between species, meaning that it does not follow species boundaries. Vibrio metoecus does not encode toxigenic V. cholerae major virulence factors, the cholera toxin and toxin-coregulated pilus. However, some of the pathogenicity islands found in pandemic V. cholerae were either present in the common ancestor it shares with V. metoecus, or acquired by clinical and environmental V. metoecus in partial fragments. The virulence factors of V. cholerae are therefore both more ancient and more widespread than previously believed. There is high interspecies recombination in the core genome, which has been detected in 24% of the single-copy core genes, including genes involved in pathogenicity. Vibrio metoecus was six times more often the recipient of DNA from V. cholerae as it was the donor, indicating a strong bias in the direction of gene transfer in the environment. © The Author(s) 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. JF - Genome biology and evolution AU - Orata, Fabini D AU - Kirchberger, Paul C AU - Méheust, Raphaël AU - Barlow, E Jed AU - Tarr, Cheryl L AU - Boucher, Yan AD - Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada. ; Unité Mixte de Recherche 7138, Evolution Paris-Seine, Institut de Biologie Paris-Seine, Université Pierre et Marie Curie, Paris, France. ; Department of Computing Science, University of Alberta, Edmonton, Alberta, Canada. ; Enteric Diseases Laboratory Branch, Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA. ; Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada yboucher@ualberta.ca. Y1 - 2015/10/09/ PY - 2015 DA - 2015 Oct 09 SP - 2941 EP - 2954 VL - 7 IS - 10 KW - DNA, Bacterial KW - 0 KW - Virulence Factors KW - Index Medicus KW - Vibrio cholerae KW - comparative genomics KW - genomic islands KW - Vibrio metoecus KW - integron KW - horizontal gene transfer KW - Phylogeny KW - Comparative Genomic Hybridization KW - Base Sequence KW - Genomic Islands KW - Integrons KW - Humans KW - Molecular Sequence Data KW - Virulence Factors -- genetics KW - Gene-Environment Interaction KW - Evolution, Molecular KW - Environmental Microbiology KW - Vibrio -- genetics KW - Vibrio cholerae -- genetics KW - Genes, Bacterial KW - DNA, Bacterial -- genetics KW - Vibrio cholerae -- isolation & purification KW - Vibrio -- isolation & purification UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1728671782?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Genome+biology+and+evolution&rft.atitle=The+Dynamics+of+Genetic+Interactions+between+Vibrio+metoecus+and+Vibrio+cholerae%2C+Two+Close+Relatives+Co-Occurring+in+the+Environment.&rft.au=Orata%2C+Fabini+D%3BKirchberger%2C+Paul+C%3BM%C3%A9heust%2C+Rapha%C3%ABl%3BBarlow%2C+E+Jed%3BTarr%2C+Cheryl+L%3BBoucher%2C+Yan&rft.aulast=Orata&rft.aufirst=Fabini&rft.date=2015-10-09&rft.volume=7&rft.issue=10&rft.spage=2941&rft.isbn=&rft.btitle=&rft.title=Genome+biology+and+evolution&rft.issn=1759-6653&rft_id=info:doi/10.1093%2Fgbe%2Fevv193 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2016-07-28 N1 - Date created - 2015-10-30 N1 - Date revised - 2017-01-14 N1 - Genetic sequence - PRJNA281423; BioProject N1 - SuppNotes - Cited By: Trends Microbiol. 2000 Mar;8(3):128-33 [10707066] BMC Genomics. 2008;9:75 [18261238] Environ Microbiol. 2008 Apr;10(4):1024-38 [18190517] PLoS Pathog. 2008 Feb 8;4(2):e37 [18282099] J Bacteriol. 2008 Nov;190(21):7232-40 [18757542] Bioinformatics. 2009 Mar 1;25(5):664-5 [19151094] J Bacteriol. 2009 Apr;191(7):2296-306 [19151136] Proc Natl Acad Sci U S A. 2009 Sep 8;106(36):15442-7 [19720995] Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19126-31 [19855009] Microb Ecol. 2010 Jan;59(1):1-13 [19830476] BMC Microbiol. 2010;10:154 [20507608] FEMS Microbiol Lett. 2010 Jul;308(2):130-7 [20528940] Proc Natl Acad Sci U S A. 2010 Dec 7;107(49):21134-9 [21078967] Bioinformatics. 2011 Feb 15;27(4):592-3 [21169378] Mol Biol Evol. 2011 Apr;28(4):1393-405 [21172835] MBio. 2011;2(2). pii: e00335-10. doi: 10.1128/mBio.00335-10 [21486909] Methods Mol Biol. 2012;801:189-211 [21987255] Bull World Health Organ. 2012 Mar 1;90(3):209-218A [22461716] Bioinformatics. 2012 Jun 15;28(12):1647-9 [22543367] BMC Genomics. 2012;13:202 [22621371] J Med Microbiol. 2012 Dec;61(Pt 12):1736-45 [22977073] MBio. 2013;4(4). pii: e00398-13. doi: 10.1128/mBio.00398-13 [23820394] Nat Commun. 2013;4:2304 [23942190] Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1556-61 [11818571] Int J Med Microbiol. 2002 Jul;292(2):115-25 [12195734] Microbiology. 2002 Nov;148(Pt 11):3681-93 [12427958] Mol Microbiol. 2003 May;48(3):753-64 [12694619] Genome Res. 2003 Sep;13(9):2178-89 [12952885] Clin Microbiol Rev. 2004 Jan;17(1):14-56 [14726454] Nucleic Acids Res. 2000 Jan 1;28(1):33-6 [10592175] Infect Immun. 2000 Mar;68(3):1491-7 [10678965] Infect Immun. 2004 Mar;72(3):1391-6 [14977943] Nat Rev Microbiol. 2004 May;2(5):414-24 [15100694] FEMS Microbiol Lett. 2004 May 15;234(2):289-95 [15135535] Infect Immun. 2004 Jun;72(6):3577-83 [15155667] Protein Eng. 1999 Feb;12(2):85-94 [10195279] Nature. 1999 May 27;399(6734):375-9 [10360577] J Biol Chem. 1965 Apr;240:1725-30 [14285515] Microbiology. 2004 Dec;150(Pt 12):4053-63 [15583158] BMC Bioinformatics. 2005;6:2 [15634352] Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2567-72 [15701695] Proc Natl Acad Sci U S A. 2005 Sep 27;102(39):13950-5 [16172379] PLoS Biol. 2005 Oct;3(10):e316 [16122348] Nat Rev Microbiol. 2006 Aug;4(8):608-20 [16845431] Int J Syst Evol Microbiol. 2007 Jan;57(Pt 1):81-91 [17220447] Mol Microbiol. 2007 Feb;63(4):995-1007 [17233827] Trends Microbiol. 2007 Jul;15(7):301-9 [17566739] Proc Natl Acad Sci U S A. 2007 Nov 13;104(46):18229-34 [17986616] Bioinformatics. 2007 Nov 1;23(21):2947-8 [17846036] Mol Microbiol. 2004 Oct;54(1):264-77 [15458421] J Clin Microbiol. 1981 Dec;14(6):631-9 [7037833] Proc Natl Acad Sci U S A. 1987 May;84(9):2833-7 [2883655] Mol Microbiol. 1989 Dec;3(12):1669-83 [2560119] J Mol Biol. 1990 Oct 5;215(3):403-10 [2231712] Antimicrob Agents Chemother. 1995 Jan;39(1):155-62 [7695299] Science. 1996 Jun 28;272(5270):1910-4 [8658163] Proc Natl Acad Sci U S A. 1997 Jan 7;94(1):265-70 [8990197] Science. 1998 Apr 24;280(5363):605-8 [9554855] Bioinformatics. 2014 May 1;30(9):1297-9 [24420766] Bioinformatics. 2014 May 1;30(9):1312-3 [24451623] Elife. 2014;3:e03497 [25161196] Int J Syst Evol Microbiol. 2014 Sep;64(Pt 9):3208-14 [24972615] Curr Opin Microbiol. 2015 Feb;23:148-54 [25483351] J Bacteriol. 2015 Jul;197(13):2150-9 [25897030] Nature. 2000 Aug 3;406(6795):477-83 [10952301] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1093/gbe/evv193 ER - TY - JOUR T1 - Cigarette Smoking Prevalence Among Adults Working in the Health Care and Social Assistance Sector, 2008 to 2012 AN - 1762353836; PQ0002503698 AB - Objective: The primary objective of this study was to estimate current smoking among workers in the health care and social assistance sector. Methods: We analyzed the 2008 to 2012 National Health Interview Survey data for adults (age 18 years or more) working in health care and social assistance sector who reported current cigarette smoking. Results: Of the approximately 18.9 million health care and social assistance workers, 16.0% were current cigarette smokers. Smoking prevalence was highest in women (16.9%) and among workers: age 25 to 44 years (17.7%); with a high school education or less (24.4%); with income less than $35,000 (19.5%); with no health insurance (28.5%); in the nursing and residential care facilities (26.9%) industry; and in the material recording, scheduling, dispatching, and distributing (34.7%) occupations. Conclusions: These findings suggest that specific group of workers in the health care and social assistance sector might particularly benefit from cessation programs and incentives to quit smoking. JF - Journal of Occupational and Environmental Medicine AU - Syamlal, Girija AU - Mazurek, Jacek M AU - Storey, Eileen AU - Dube, Shanta R AD - Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia, gsyamlal@cdc.gov Y1 - 2015/10// PY - 2015 DA - October 2015 SP - 1107 EP - 1112 PB - Williams & Wilkins, 351 W. Camden St. Baltimore MD 21201 United States VL - 57 IS - 10 SN - 1076-2752, 1076-2752 KW - Health & Safety Science Abstracts KW - Age KW - Education KW - Health care KW - Cigarettes KW - Cigarette smoking KW - Incentives KW - Insurance KW - Recording KW - Income KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1762353836?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Cigarette+Smoking+Prevalence+Among+Adults+Working+in+the+Health+Care+and+Social+Assistance+Sector%2C+2008+to+2012&rft.au=Syamlal%2C+Girija%3BMazurek%2C+Jacek+M%3BStorey%2C+Eileen%3BDube%2C+Shanta+R&rft.aulast=Syamlal&rft.aufirst=Girija&rft.date=2015-10-01&rft.volume=57&rft.issue=10&rft.spage=1107&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0000000000000529 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Last updated - 2016-02-29 N1 - SubjectsTermNotLitGenreText - Education; Age; Cigarettes; Health care; Cigarette smoking; Incentives; Insurance; Income; Recording DO - http://dx.doi.org/10.1097/JOM.0000000000000529 ER - TY - JOUR T1 - Use of random forest to estimate population attributable fractions from a case-control study of Salmonella enterica serotype Enteritidis infections AN - 1727687549; PQ0002023236 AB - To design effective food safety programmes we need to estimate how many sporadic foodborne illnesses are caused by specific food sources based on case-control studies. Logistic regression has substantive limitations for analysing structured questionnaire data with numerous exposures and missing values. We adapted random forest to analyse data of a case-control study of Salmonella enterica serotype Enteritidis illness for source attribution. For estimation of summary population attributable fractions (PAFs) of exposures grouped into transmission routes, we devised a counterfactual estimator to predict reductions in illness associated with removing grouped exposures. For the purpose of comparison, we fitted the data using logistic regression models with stepwise forward and backward variable selection. Our results show that the forward and backward variable selection of logistic regression models were not consistent for parameter estimation, with different significant exposures identified. By contrast, the random forest model produced estimated PAFs of grouped exposures consistent in rank order with results obtained from outbreak data, with egg-related exposures having the highest estimated PAF (22.1%, 95% confidence interval 8.5-31.8). Random forest might be structurally more coherent and efficient than logistic regression models for attributing Salmonella illnesses to sources involving many causal pathways. JF - Epidemiology and Infection AU - GU, W AU - Vieira, A R AU - Hoekstra, R M AU - Griffin, P M AU - Cole, D AD - Centers for Disease Control and Prevention, Enteric Diseases Epidemiology Branch, Atlanta, GA, USA, vhg8@cdc.gov Y1 - 2015/10// PY - 2015 DA - October 2015 SP - 2786 EP - 2794 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 143 IS - 13 SN - 0950-2688, 0950-2688 KW - Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts KW - Inventories KW - Data processing KW - Serotypes KW - Food KW - Forests KW - Food contamination KW - Pest outbreaks KW - Infection KW - Food-borne diseases KW - Models KW - Disease transmission KW - Platelet-activating factor KW - Salmonella enterica KW - Food sources KW - Regression analysis KW - Outbreaks KW - J 02400:Human Diseases KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727687549?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Use+of+random+forest+to+estimate+population+attributable+fractions+from+a+case-control+study+of+Salmonella+enterica+serotype+Enteritidis+infections&rft.au=GU%2C+W%3BVieira%2C+A+R%3BHoekstra%2C+R+M%3BGriffin%2C+P+M%3BCole%2C+D&rft.aulast=GU&rft.aufirst=W&rft.date=2015-10-01&rft.volume=143&rft.issue=13&rft.spage=2786&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS095026881500014X LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Number of references - 26 N1 - Last updated - 2016-03-30 N1 - SubjectsTermNotLitGenreText - Platelet-activating factor; Inventories; Serotypes; Data processing; Food; Food sources; Regression analysis; Forests; Infection; Pest outbreaks; Disease transmission; Models; Outbreaks; Food contamination; Food-borne diseases; Salmonella enterica DO - http://dx.doi.org/10.1017/S095026881500014X ER - TY - CPAPER T1 - Enterovirus D68: A Rare Pathogen Reemerges T2 - 2015 Interscience Conference of Antimicrobial Agents and Chemotherapy and International Congress of Chemotherapy and Infection (ICAAC/ICC 2015) AN - 1704517103; 6355182 JF - 2015 Interscience Conference of Antimicrobial Agents and Chemotherapy and International Congress of Chemotherapy and Infection (ICAAC/ICC 2015) AU - Midgley, Claire Y1 - 2015/09/17/ PY - 2015 DA - 2015 Sep 17 KW - Pathogens KW - Enterovirus UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1704517103?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2015+Interscience+Conference+of+Antimicrobial+Agents+and+Chemotherapy+and+International+Congress+of+Chemotherapy+and+Infection+%28ICAAC%2FICC+2015%29&rft.atitle=Enterovirus+D68%3A+A+Rare+Pathogen+Reemerges&rft.au=Midgley%2C+Claire&rft.aulast=Midgley&rft.aufirst=Claire&rft.date=2015-09-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2015+Interscience+Conference+of+Antimicrobial+Agents+and+Chemotherapy+and+International+Congress+of+Chemotherapy+and+Infection+%28ICAAC%2FICC+2015%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/start.aspx?mkey={7A574A80-EAB1-4B50-B343-4695DF14907E} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-07-31 N1 - Last updated - 2015-08-18 ER - TY - CPAPER T1 - Bacterial Antimicrobial Susceptibility Testing (CLSI) T2 - 2015 Interscience Conference of Antimicrobial Agents and Chemotherapy and International Congress of Chemotherapy and Infection (ICAAC/ICC 2015) AN - 1704515759; 6355159 JF - 2015 Interscience Conference of Antimicrobial Agents and Chemotherapy and International Congress of Chemotherapy and Infection (ICAAC/ICC 2015) AU - Patel, Jean Y1 - 2015/09/17/ PY - 2015 DA - 2015 Sep 17 KW - Antimicrobial agents UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1704515759?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2015+Interscience+Conference+of+Antimicrobial+Agents+and+Chemotherapy+and+International+Congress+of+Chemotherapy+and+Infection+%28ICAAC%2FICC+2015%29&rft.atitle=Bacterial+Antimicrobial+Susceptibility+Testing+%28CLSI%29&rft.au=Patel%2C+Jean&rft.aulast=Patel&rft.aufirst=Jean&rft.date=2015-09-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2015+Interscience+Conference+of+Antimicrobial+Agents+and+Chemotherapy+and+International+Congress+of+Chemotherapy+and+Infection+%28ICAAC%2FICC+2015%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/start.aspx?mkey={7A574A80-EAB1-4B50-B343-4695DF14907E} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-07-31 N1 - Last updated - 2015-08-18 ER - TY - CPAPER T1 - The Global Epidemiology of Meningococcal Disease T2 - 2015 Interscience Conference of Antimicrobial Agents and Chemotherapy and International Congress of Chemotherapy and Infection (ICAAC/ICC 2015) AN - 1704510797; 6355208 JF - 2015 Interscience Conference of Antimicrobial Agents and Chemotherapy and International Congress of Chemotherapy and Infection (ICAAC/ICC 2015) AU - MacNeil, Jessica Y1 - 2015/09/17/ PY - 2015 DA - 2015 Sep 17 KW - Epidemiology KW - meningococcal disease KW - Neisseria meningitidis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1704510797?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2015+Interscience+Conference+of+Antimicrobial+Agents+and+Chemotherapy+and+International+Congress+of+Chemotherapy+and+Infection+%28ICAAC%2FICC+2015%29&rft.atitle=The+Global+Epidemiology+of+Meningococcal+Disease&rft.au=MacNeil%2C+Jessica&rft.aulast=MacNeil&rft.aufirst=Jessica&rft.date=2015-09-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2015+Interscience+Conference+of+Antimicrobial+Agents+and+Chemotherapy+and+International+Congress+of+Chemotherapy+and+Infection+%28ICAAC%2FICC+2015%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/start.aspx?mkey={7A574A80-EAB1-4B50-B343-4695DF14907E} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-07-31 N1 - Last updated - 2015-08-18 ER - TY - CPAPER T1 - Historical Perspectives and Current Epidemiology T2 - 55th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2015) AN - 1697992040; 6353871 JF - 55th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2015) AU - Rollin, Pierre Y1 - 2015/09/17/ PY - 2015 DA - 2015 Sep 17 KW - Historical account KW - Epidemiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1697992040?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=55th+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2015%29&rft.atitle=Historical+Perspectives+and+Current+Epidemiology&rft.au=Rollin%2C+Pierre&rft.aulast=Rollin&rft.aufirst=Pierre&rft.date=2015-09-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=55th+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2015%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/start.aspx?mkey={7A574A80-EAB1-4B50-B343-4695DF14907E} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-06-30 N1 - Last updated - 2015-07-23 ER - TY - JOUR T1 - Nosocomial Cholera Outbreak in a Mental Hospital: Challenges and Lessons Learnt from Butabika National Referral Mental Hospital, Uganda AN - 1827926771; PQ0003669065 AB - During the last four decades, Uganda has experienced repeated cholera outbreaks in communities; no cholera outbreaks have been reported in Ugandan health facilities. In October 2008, a unique cholera outbreak was confirmed in Butabika National Mental Referral Hospital (BNMRH), Uganda. This article describes actions taken to control the outbreak, challenges, and lessons learnt. We reviewed patient and hospital reports for clinical symptoms and signs, treatment and outcome, patient mental diagnosis, and challenges noted during management of patients and contacts. Out of 114 BNMRH patients on two affected wards, 18 cholera cases and five deaths were documented for an attack rate of 15.8% and a case fatality rate of 28%. Wards and surroundings were intensively disinfected and 96 contacts (psychiatric patients) in the affected wards received chemoprophylaxis with oral ciprofloxacin 500 mg twice daily until November 5, 2008. We documented a nosocomial cholera outbreak in BNMRH with a high case fatality of 28% compared with the national average of 2.4% for cholera outbreaks in communities. To avoid cholera outbreaks and potentially high mortality among patients in mental institutions, procedures for prompt diagnosis, treatment, disinfection, and prophylaxis are needed and preemptive use of oral cholera vaccines should be considered. JF - American Journal of Tropical Medicine and Hygiene AU - Bwire, Godfrey AU - Malimbo, Mugagga AU - Kagirita, Atek AU - Makumbi, Issa AU - Mintz, Eric AU - Mengel, Martin A AU - Orach, Christopher Garimoi AD - Control of Diarrheal Diseases Section, Ministry of Health, Kampala, Uganda, emintz@cdc.gov Y1 - 2015/09// PY - 2015 DA - September 2015 SP - 534 EP - 538 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 93 IS - 3 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Symptoms KW - Disinfection KW - Disease control KW - Infection KW - Ciprofloxacin KW - Cholera KW - Bacteria KW - Mortality KW - Pathogenic bacteria KW - Bacterial diseases KW - Uganda KW - Prophylaxis KW - Outbreaks KW - Vaccines KW - Hygiene KW - Mortality causes KW - Hospitals KW - K 03400:Human Diseases KW - Q1 08485:Species interactions: pests and control KW - J 02400:Human Diseases KW - Q5 08524:Public health, medicines, dangerous organisms KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1827926771?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Nosocomial+Cholera+Outbreak+in+a+Mental+Hospital%3A+Challenges+and+Lessons+Learnt+from+Butabika+National+Referral+Mental+Hospital%2C+Uganda&rft.au=Bwire%2C+Godfrey%3BMalimbo%2C+Mugagga%3BKagirita%2C+Atek%3BMakumbi%2C+Issa%3BMintz%2C+Eric%3BMengel%2C+Martin+A%3BOrach%2C+Christopher+Garimoi&rft.aulast=Bwire&rft.aufirst=Godfrey&rft.date=2015-09-01&rft.volume=93&rft.issue=3&rft.spage=534&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0730 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-10-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Disinfection; Symptoms; Pathogenic bacteria; Bacterial diseases; Disease control; Prophylaxis; Vaccines; Hygiene; Mortality causes; Mortality; Ciprofloxacin; Cholera; Hospitals; Bacteria; Outbreaks; Infection; Uganda DO - http://dx.doi.org/10.4269/ajtmh.14-0730 ER - TY - JOUR T1 - The Role of HIV in the Household Introduction and Transmission of Influenza in an Urban Slum, Nairobi, Kenya, 2008-2011 AN - 1773828542; PQ0002695537 AB - Background. Little is known about how human immunodeficiency virus (HIV) infection affects influenza transmission within homes in sub-Saharan Africa. Methods. We used respiratory illness surveillance and HIV testing data gathered in Kibera, an urban slum in Nairobi, Kenya, to examine the impact of HIV status on (1) introducing influenza to the home and (2) transmitting influenza to household contacts. Results. While HIV status did not affect the likelihood of being an influenza index case, household contacts of HIV-infected influenza index cases had twice the risk of developing secondary influenza-like illness than contacts of HIV-negative index cases. Conclusions. HIV-infected influenza index cases may facilitate transmission of influenza within the home. JF - Journal of Infectious Diseases AU - Judd, Michael C AU - Emukule, Gideon O AU - Njuguna, Henry AU - McMorrow, Meredith L AU - Arunga, Geoffrey O AU - Katz, Mark A AU - Montgomery, Joel M AU - Wong, Joshua M AU - Breiman, Robert F AU - Mott, Joshua A AD - Department of Epidemiology, Rollins School of Public Health, Emory University, jmott@cdc.gov Y1 - 2015/09/01/ PY - 2015 DA - 2015 Sep 01 SP - 740 EP - 744 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 212 IS - 5 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - influenza transmission KW - influenza-like illness KW - HIV KW - Kenya KW - Kibera KW - slum KW - informal settlement KW - Data processing KW - Kenya, Nairobi KW - Infection KW - Disease transmission KW - Influenza KW - Infectious diseases KW - Human immunodeficiency virus KW - Households KW - Africa KW - Slums KW - V 22360:AIDS and HIV KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1773828542?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=The+Role+of+HIV+in+the+Household+Introduction+and+Transmission+of+Influenza+in+an+Urban+Slum%2C+Nairobi%2C+Kenya%2C+2008-2011&rft.au=Judd%2C+Michael+C%3BEmukule%2C+Gideon+O%3BNjuguna%2C+Henry%3BMcMorrow%2C+Meredith+L%3BArunga%2C+Geoffrey+O%3BKatz%2C+Mark+A%3BMontgomery%2C+Joel+M%3BWong%2C+Joshua+M%3BBreiman%2C+Robert+F%3BMott%2C+Joshua+A&rft.aulast=Judd&rft.aufirst=Michael&rft.date=2015-09-01&rft.volume=212&rft.issue=5&rft.spage=740&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiv106 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-03-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Influenza; Data processing; Infection; Disease transmission; Infectious diseases; Human immunodeficiency virus; Households; Slums; Kenya, Nairobi; Africa DO - http://dx.doi.org/10.1093/infdis/jiv106 ER - TY - JOUR T1 - Evaluation of the national tuberculosis surveillance program in Haiti AN - 1727693756; PQ0002041453 AB - OBJECTIVE: To assess the quality of tuberculosis (TB) surveillance in Haiti, including whether underreporting from facilities to the national level contributes to low national case registration. METHODS: We collected 2010 and 2012 TB case totals, reviewed laboratory registries, and abstracted individual TB case reports from 32 of 263 anti-tuberculosis treatment facilities randomly selected after stratification/weighting toward higher-volume facilities. We compared site results to national databases maintained by a non-governmental organization partner (International Child Care [ICC]) for 2010 and 2012, and the National TB Program (Programme National de Lutte contre la Tuberculose, PNLT) for 2012 only. RESULTS: Case registries were available at 30/32 facilities for 2010 and all 32 for 2012. Totals of 3711 (2010) and 4143 (2012) cases were reported at the facilities. Case totals per site were higher in site registries than in the national databases by 361 (9.7%) (ICC 2010), 28 (0.8%) (ICC 2012), and 31 (0.8%) cases (PNLT 2012). Of abstracted individual cases, respectively 11.8% and 6.8% were not recorded in national databases for 2010 (n = 323) and 2012 (n = 351). CONCLUSIONS: The evaluation demonstrated an improvement in reporting registered TB cases to the PNLT in Haiti between 2010 and 2012. Further improvement in case notification will require enhanced case detection and diagnosis. JF - International Journal of Tuberculosis and Lung Disease AU - Salyer, S J AU - Fitter, D L AU - Milo, R AU - Blanton, C AU - Ho, J L AU - Geffrard, H AU - Morose, W AU - Marston, B J AD - Division of Global Health Protection, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, wig9@cdc.gov Y1 - 2015/09// PY - 2015 DA - Sep 2015 SP - 1045 EP - 1050 PB - International Union Against Tuberculosis and Lung Disease, 68 bvd Saint-Michel Paris 75006 France VL - 19 IS - 9 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology KW - TB KW - tuberculosis KW - surveillance KW - PNLT KW - Haiti KW - Databases KW - Computer programs KW - Case reports KW - Mycobacterium KW - Non-governmental organizations KW - Reviews KW - Lung diseases KW - Tuberculosis KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727693756?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Evaluation+of+the+national+tuberculosis+surveillance+program+in+Haiti&rft.au=Salyer%2C+S+J%3BFitter%2C+D+L%3BMilo%2C+R%3BBlanton%2C+C%3BHo%2C+J+L%3BGeffrard%2C+H%3BMorose%2C+W%3BMarston%2C+B+J&rft.aulast=Salyer&rft.aufirst=S&rft.date=2015-09-01&rft.volume=19&rft.issue=9&rft.spage=1045&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/10.5588%2Fijtld.15.0051 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2015-11-16 N1 - SubjectsTermNotLitGenreText - Computer programs; Databases; Case reports; Non-governmental organizations; Reviews; Lung diseases; Tuberculosis; Mycobacterium DO - http://dx.doi.org/10.5588/ijtld.15.0051 ER - TY - JOUR T1 - Introduction of Monkeypox into a Community and Household: Risk Factors and Zoonotic Reservoirs in the Democratic Republic of the Congo AN - 1727697478; PQ0002136585 AB - An increased incidence of monkeypox (MPX) infections in the Democratic Republic of the Congo was noted by the regional surveillance system in October 2013. Little information exists regarding how MPX is introduced Into the community and the factors associated with transmission within the household. Sixty-eight wild animals were collected and tested for Orthopoxvirus. Two of three rope squirrels (Funisciurus sp.) were positive for antibodies to Orthopoxviruses; however, no increased risk was associated with the consumption or preparation of rope squirrels. A retrospective cohort investigation and a case-control investigation were performed to identify risk factors affecting the introduction of monkeypox virus (MPXV) into the community and transmission within the home. School-age males were the individuals most frequently identified as the first person infected in the household and were the group most frequently affected overall. Risk factors of acquiring MPXV in a household included sleeping in the same room or bed, or using the same plate or cup as the primary case. There was no significant risk associated with eating or processing of wild animals. Activities associated with an increased risk of MPXV transmission all have potential for virus exposure to the mucosa. JF - American Journal of Tropical Medicine and Hygiene AU - Nolen, Leisha Diane AU - Osadebe, Lynda AU - Katomba, Jacques AU - Likofata, Jacques AU - Mukadi, Daniel AU - Monroe, Benjamin AU - Doty, Jeffrey AU - Kalemba, Lem's AU - Malekani, Jean AU - Kabamba, Joelle AD - U.S. Centers for Disease Control and Prevention, Bacterial Special Pathogens Branch, Atlanta, Georgia, xdf8@cdc.gov Y1 - 2015/08// PY - 2015 DA - August 2015 SP - 410 EP - 415 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 93 IS - 2 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Orthopoxvirus KW - Monkeypox KW - Antibodies KW - Risk factors KW - Mucosa KW - Surveillance and enforcement KW - Infection KW - Hygiene KW - Risks KW - Monkeypox virus KW - K 03400:Human Diseases KW - Q5 08504:Effects on organisms KW - J 02400:Human Diseases KW - Q1 08604:Stock assessment and management KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727697478?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Introduction+of+Monkeypox+into+a+Community+and+Household%3A+Risk+Factors+and+Zoonotic+Reservoirs+in+the+Democratic+Republic+of+the+Congo&rft.au=Nolen%2C+Leisha+Diane%3BOsadebe%2C+Lynda%3BKatomba%2C+Jacques%3BLikofata%2C+Jacques%3BMukadi%2C+Daniel%3BMonroe%2C+Benjamin%3BDoty%2C+Jeffrey%3BKalemba%2C+Lem%27s%3BMalekani%2C+Jean%3BKabamba%2C+Joelle&rft.aulast=Nolen&rft.aufirst=Leisha&rft.date=2015-08-01&rft.volume=93&rft.issue=2&rft.spage=410&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.15-0168 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Antibodies; Surveillance and enforcement; Hygiene; Risks; Monkeypox; Risk factors; Mucosa; Infection; Orthopoxvirus; Monkeypox virus DO - http://dx.doi.org/10.4269/ajtmh.15-0168 ER - TY - JOUR T1 - Case Report: Thirty-Seven Human Cases of Sparganosis from Ethiopia and South Sudan Caused by Spirometra Spp. AN - 1727694726; PQ0002136572 AB - Thirty-seven unusual specimens, three from Ethiopia and 34 from South Sudan, were submitted since 2012 for further identification by the Ethiopian Dracunculiasis Eradication Program (EDEP) and the South Sudan Guinea Worm Eradication Program (SSGWEP), respectively. Although the majority of specimens emerged from sores or breaks in the skin, there was concern that they did not represent bona fide cases of Dracunculus medinensis and that they needed detailed examination and identification as provided by the World Health Organization Collaborating Center (WHO CC) at Centers for Disease Control and Prevention (CDC). All 37 specimens were identified on microscopic study as larval tapeworms of the spargana type, and DNA sequence analysis of seven confirmed the identification of Spirometra sp. Age of cases ranged between 7 and 70 years (mean 25 years); 21 (57%) patients were male and 16 were female. The presence of spargana in open skin lesions is somewhat atypical, but does confirm the fact that populations living in these remote areas are either ingesting infected copepods in unsafe drinking water or, more likely, eating poorly cooked paratenic hosts harboring the parasite. JF - American Journal of Tropical Medicine and Hygiene AU - Eberhard, Mark L AU - Thiele, Elizabeth A AU - Yembo, Gole E AU - Yibi, Makoy S AU - Cama, Vitaliano A AU - Ruiz-Tiben, Ernesto AD - Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia, mle1@cdc.gov Y1 - 2015/08// PY - 2015 DA - August 2015 SP - 350 EP - 355 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 93 IS - 2 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts KW - Parasites KW - Age KW - Nucleotide sequence KW - Disease control KW - Spirometra KW - Hosts KW - Public health KW - Ethiopia KW - Drinking Water KW - Ectoparasites KW - Guinea KW - Copepoda KW - Lesions KW - Skin KW - Zooplankton KW - Larvae KW - Dracunculus medinensis KW - Sudan KW - Endoparasites KW - Prevention KW - Skin diseases KW - Case reports KW - DNA KW - Drinking water KW - Hygiene KW - New species KW - H 3000:Environment and Ecology KW - K 03400:Human Diseases KW - J 02400:Human Diseases KW - Q1 08485:Species interactions: pests and control KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727694726?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Case+Report%3A+Thirty-Seven+Human+Cases+of+Sparganosis+from+Ethiopia+and+South+Sudan+Caused+by+Spirometra+Spp.&rft.au=Eberhard%2C+Mark+L%3BThiele%2C+Elizabeth+A%3BYembo%2C+Gole+E%3BYibi%2C+Makoy+S%3BCama%2C+Vitaliano+A%3BRuiz-Tiben%2C+Ernesto&rft.aulast=Eberhard&rft.aufirst=Mark&rft.date=2015-08-01&rft.volume=93&rft.issue=2&rft.spage=350&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.15-0236 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Drinking Water; Ectoparasites; Nucleotide sequence; Zooplankton; Disease control; Hosts; Endoparasites; Hygiene; New species; Parasites; Age; Case reports; Skin diseases; Drinking water; Prevention; Skin; DNA; Larvae; Lesions; Public health; Copepoda; Dracunculus medinensis; Spirometra; Ethiopia; Guinea; Sudan DO - http://dx.doi.org/10.4269/ajtmh.15-0236 ER - TY - JOUR T1 - Jamestown Canyon Virus Disease in the United States-2000-2013 AN - 1727694474; PQ0002136578 AB - Jamestown Canyon virus (JCV) is a mosquito-borne orthobunyavirus in the California serogroup that can cause an acute febrile Illness, meningitis, or meningoencephalitis. We describe epidemiologic and clinical features for JCV disease cases occurring in the United States during 2000-2013. A case of JCV disease was defined as an acute illness in a person with laboratory evidence of a recent JCV infection. During 2000-2013, we identified 31 cases of JCV disease in residents of 13 states. The median age was 48 years (range, 10-69) and 21 (68%) were male. Eleven (35%) case patients had meningoencephalitis, 6 (19%) meningitis, 7 (23%) fever without neurologic involvement, and 7 (23%) had an unknown clinical syndrome. Fifteen (48%) were hospitalized and there were no deaths. Health-care providers and public health officials should consider JCV disease in the differential diagnoses of viral meningitis and encephalitis, obtain appropriate specimens for testing, and report cases to public health authorities. JF - American Journal of Tropical Medicine and Hygiene AU - Pastula, Daniel M AU - Johnson, Diep K Hoang AU - White, Jennifer L AU - Dupuis, Alan P, II AU - Fischer, Marc AU - Staples, J Erin AD - EIS Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia, estaples@cdc.gov Y1 - 2015/08// PY - 2015 DA - August 2015 SP - 384 EP - 389 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 93 IS - 2 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts KW - Mortality KW - Aseptic meningitis KW - Symptoms KW - Age KW - Meningoencephalitis KW - Infection KW - Encephalitis KW - Meningitis KW - Public health KW - Orthobunyavirus KW - Fever KW - Viral diseases KW - INE, USA, California KW - Canyons KW - Hygiene KW - Jamestown canyon virus KW - Aquatic insects KW - Hospitals KW - K 03400:Human Diseases KW - Q1 08484:Species interactions: parasites and diseases KW - J 02400:Human Diseases KW - H 12000:Epidemiology and Public Health KW - Q5 08524:Public health, medicines, dangerous organisms KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727694474?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Jamestown+Canyon+Virus+Disease+in+the+United+States-2000-2013&rft.au=Pastula%2C+Daniel+M%3BJohnson%2C+Diep+K+Hoang%3BWhite%2C+Jennifer+L%3BDupuis%2C+Alan+P%2C+II%3BFischer%2C+Marc%3BStaples%2C+J+Erin&rft.aulast=Pastula&rft.aufirst=Daniel&rft.date=2015-08-01&rft.volume=93&rft.issue=2&rft.spage=384&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.15-0196 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Symptoms; Viral diseases; Hygiene; Aquatic insects; Public health; Fever; Aseptic meningitis; Age; Meningoencephalitis; Infection; Encephalitis; Meningitis; Mortality; Canyons; Hospitals; Orthobunyavirus; Jamestown canyon virus; INE, USA, California DO - http://dx.doi.org/10.4269/ajtmh.15-0196 ER - TY - JOUR T1 - Implications of Genome-Based Discrimination between Clostridium botulinum Group I and Clostridium sporogenes Strains for Bacterial Taxonomy AN - 1709185128; PQ0001900809 AB - Taxonomic classification of Clostridium botulinum is based on the production of botulinum neurotoxin (BoNT), while closely related, nontoxic organisms are classified as Clostridium sporogenes. However, this taxonomic organization does not accurately mirror phylogenetic relationships between these species. A phylogenetic reconstruction using 2,016 orthologous genes shared among strains of C. botulinum group I and C. sporogenes clearly separated these two species into discrete clades which showed similar to 93% average nucleotide identity (ANI) between them. Clustering of strains based on the presence of variable orthologs revealed 143 C. sporogenes clade-specific genetic signatures, a subset of which were further evaluated for their ability to correctly classify a panel of presumptive C. sporogenes strains by PCR. Genome sequencing of several C. sporogenes strains lacking these signatures confirmed that they clustered with C. botulinum strains in a core genome phylogenetic tree. Our analysis also identified C. botulinum strains that contained C. sporogenes clade-specific signatures and phylogenetically clustered with C. sporogenes strains. The genome sequences of two bont/B2-containing strains belonging to the C. sporogenes clade contained regions with similarity to a bont-bearing plasmid (pCLD), while two different strains belonging to the C. botulinum clade carried bont/B2 on the chromosome. These results indicate that bont/B2 was likely acquired by C. sporogenes strains through horizontal gene transfer. The genome-based classification of these species used to identify candidate genes for the development of rapid assays for molecular identification may be applicable to additional bacterial species that are challenging with respect to their classification. JF - Applied and Environmental Microbiology AU - Weigand, Michael R AU - Pena-Gonzalez, Angela AU - Shirey, Timothy B AU - Broeker, Robin G AU - Ishaq, Maliha K AU - Konstantinidis, Konstantinos T AU - Raphael, Brian H AD - School of Civil & Environmental Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA, BRaphael@cdc.gov. PY - 2015 SP - 5420 EP - 5429 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 81 IS - 16 SN - 0099-2240, 0099-2240 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Phylogeny KW - Genomes KW - Bacteria KW - Clostridium sporogenes KW - Clostridium botulinum KW - Plasmids KW - Nucleotides KW - Chromosomes KW - Classification KW - Cores KW - Polymerase chain reaction KW - Taxonomy KW - Botulinum toxin KW - J 02310:Genetics & Taxonomy KW - A 01340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1709185128?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Implications+of+Genome-Based+Discrimination+between+Clostridium+botulinum+Group+I+and+Clostridium+sporogenes+Strains+for+Bacterial+Taxonomy&rft.au=Weigand%2C+Michael+R%3BPena-Gonzalez%2C+Angela%3BShirey%2C+Timothy+B%3BBroeker%2C+Robin+G%3BIshaq%2C+Maliha+K%3BKonstantinidis%2C+Konstantinos+T%3BRaphael%2C+Brian+H&rft.aulast=Weigand&rft.aufirst=Michael&rft.date=2015-08-01&rft.volume=81&rft.issue=16&rft.spage=5420&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/10.1128%2FAEM.01159-15 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-09-01 N1 - Number of references - 50 N1 - Last updated - 2016-01-21 N1 - SubjectsTermNotLitGenreText - Genomes; Phylogeny; Chromosomes; Cores; Classification; Polymerase chain reaction; Taxonomy; Botulinum toxin; Plasmids; Nucleotides; Bacteria; Clostridium sporogenes; Clostridium botulinum DO - http://dx.doi.org/10.1128/AEM.01159-15 ER - TY - JOUR T1 - The National Birth Defects Prevention Study: A review of the methods. AN - 1704354548; 26033852 AB - The National Birth Defects Prevention Study (NBDPS) is a large population-based multicenter case-control study of major birth defects in the United States. Data collection took place from 1998 through 2013 on pregnancies ending between October 1997 and December 2011. Cases could be live born, stillborn, or induced terminations, and were identified from birth defects surveillance programs in Arkansas, California, Georgia, Iowa, Massachusetts, New Jersey, New York, North Carolina, Texas, and Utah. Controls were live born infants without major birth defects identified from the same geographical regions and time periods as cases by means of either vital records or birth hospitals. Computer-assisted telephone interviews were completed with women between 6 weeks and 24 months after the estimated date of delivery. After completion of interviews, families received buccal cell collection kits for the mother, father, and infant (if living). There were 47,832 eligible cases and 18,272 eligible controls. Among these, 32,187 (67%) and 11,814 (65%), respectively, provided interview information about their pregnancies. Buccal cell collection kits with a cytobrush for at least one family member were returned by 19,065 case and 6,211 control families (65% and 59% of those who were sent a kit). More than 500 projects have been proposed by the collaborators and over 200 manuscripts published using data from the NBDPS through December 2014. The NBDPS has made substantial contributions to the field of birth defects epidemiology through its rigorous design, including case classification, detailed questionnaire and specimen collection, large study population, and collaborative activities across Centers. © 2015 Wiley Periodicals, Inc. JF - Birth defects research. Part A, Clinical and molecular teratology AU - Reefhuis, Jennita AU - Gilboa, Suzanne M AU - Anderka, Marlene AU - Browne, Marilyn L AU - Feldkamp, Marcia L AU - Hobbs, Charlotte A AU - Jenkins, Mary M AU - Langlois, Peter H AU - Newsome, Kimberly B AU - Olshan, Andrew F AU - Romitti, Paul A AU - Shapira, Stuart K AU - Shaw, Gary M AU - Tinker, Sarah C AU - Honein, Margaret A AU - National Birth Defects Prevention Study AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia. ; Massachusetts Department of Public Health, Boston, Massachusetts. ; New York State Department of Health, Albany, New York. ; University of Utah School of Medicine, Salt Lake City, Utah. ; College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas. ; Texas Department of State Health Services, Austin, Texas. ; University of North Carolina, Chapel Hill, North Carolina. ; University of Iowa, Iowa City, Iowa. ; Stanford University School of Medicine, Stanford, California. ; National Birth Defects Prevention Study Y1 - 2015/08// PY - 2015 DA - August 2015 SP - 656 EP - 669 VL - 103 IS - 8 KW - Genetic Markers KW - 0 KW - Index Medicus KW - methods KW - genetics KW - case-control KW - pregnancy KW - birth defects KW - epidemiology KW - congenital anomalies KW - Humans KW - Infant, Newborn KW - Genetic Predisposition to Disease KW - United States -- epidemiology KW - Female KW - Data Collection -- methods KW - Congenital Abnormalities -- prevention & control KW - Congenital Abnormalities -- epidemiology KW - Population Surveillance -- methods KW - Neonatal Screening -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1704354548?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Birth+defects+research.+Part+A%2C+Clinical+and+molecular+teratology&rft.atitle=The+National+Birth+Defects+Prevention+Study%3A+A+review+of+the+methods.&rft.au=Reefhuis%2C+Jennita%3BGilboa%2C+Suzanne+M%3BAnderka%2C+Marlene%3BBrowne%2C+Marilyn+L%3BFeldkamp%2C+Marcia+L%3BHobbs%2C+Charlotte+A%3BJenkins%2C+Mary+M%3BLanglois%2C+Peter+H%3BNewsome%2C+Kimberly+B%3BOlshan%2C+Andrew+F%3BRomitti%2C+Paul+A%3BShapira%2C+Stuart+K%3BShaw%2C+Gary+M%3BTinker%2C+Sarah+C%3BHonein%2C+Margaret+A%3BNational+Birth+Defects+Prevention+Study&rft.aulast=Reefhuis&rft.aufirst=Jennita&rft.date=2015-08-01&rft.volume=103&rft.issue=8&rft.spage=656&rft.isbn=&rft.btitle=&rft.title=Birth+defects+research.+Part+A%2C+Clinical+and+molecular+teratology&rft.issn=1542-0760&rft_id=info:doi/10.1002%2Fbdra.23384 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2016-05-12 N1 - Date created - 2015-08-14 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Cited By: Public Health Rep. 2001;116 Suppl 1:32-40 [11889273] Cancer Epidemiol Biomarkers Prev. 2001 Jun;10(6):687-96 [11401920] Nat Genet. 2004 Sep;36(9):955-7 [15300250] Lancet. 2000 Sep 9;356(9233):875-80 [11036891] NCHS Data Brief. 2014 Oct;(168):1-8 [25296181] N Engl J Med. 1989 Jan 5;320(1):19-23 [2909875] Genome Res. 1998 Dec;8(12):1229-31 [9872978] Neurosci Biobehav Rev. 2005 Apr;29(2):295-312 [15811500] Epidemiology. 2007 Mar;18(2):226-33 [17202867] Epidemiology. 2007 May;18(3):356-61 [17435445] Arch Pediatr Adolesc Med. 2007 Aug;161(8):745-50 [17679655] Birth Defects Res A Clin Mol Teratol. 2007 Oct;79(10):714-27 [17729292] MMWR Morb Mortal Wkly Rep. 2008 Jan 11;57(1):1-5 [18185492] Am J Obstet Gynecol. 2008 Sep;199(3):237.e1-9 [18674752] Epidemiology. 2009 Jan;20(1):27-35 [19234399] Am J Epidemiol. 2009 Oct 15;170(8):975-85 [19736223] Am J Med Genet A. 2009 Nov;149A(11):2378-86 [19839045] Am J Hum Genet. 2010 May 14;86(5):749-64 [20466091] Birth Defects Res A Clin Mol Teratol. 2011 Jul;91(7):642-8 [21630425] Am J Med Genet A. 2011 Nov;155A(11):2721-31 [21976456] J Occup Environ Hyg. 2011 Dec;8(12):718-28 [22074298] Environ Health Perspect. 2012 Jun;120(6):910-5 [22330681] Birth Defects Res A Clin Mol Teratol. 2012 Dec;94(12):996-1003 [22821801] Int J Hyg Environ Health. 2014 Mar;217(2-3):248-54 [23871272] Genet Med. 2014 Apr;16(4):329-37 [24071796] Epidemiology. 2014 Sep;25(5):773-5 [25076154] Environ Health Perspect. 2014 Aug;122(8):863-72 [24727555] Birth Defects Res A Clin Mol Teratol. 2003 Mar;67(3):193-201 [12797461] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1002/bdra.23384 ER - TY - JOUR T1 - Perinatal HIV Prevention Outcomes in U.S.-Born Versus Foreign-Born Blacks, PSD Cohort, 1995–2004 AN - 1703894200 AB - We examined differences in HIV-infected U.S.-born and foreign-born black mothers who delivered perinatally HIV-exposed and -infected children during 1995–2004 in the Pediatric Spectrum of HIV Disease Project, a longitudinal cohort study. Prevalence ratios were calculated to explain differences in perinatal HIV prevention opportunities comparing U.S.-born to foreign-born and African-born to Caribbean-born black mothers. U.S.-born compared with foreign-born HIV-infected black mothers were significantly more likely to have used cocaine or other non-intravenous illicit drugs, exchanged money or drugs for sex, known their HIV status before giving birth, received intrapartum antiretroviral (ARV) prophylaxis, and delivered a premature infant; and were significantly less likely to have received prenatal care or delivered an HIV-infected infant. African-born compared with Caribbean-born black mothers were more likely to receive intrapartum ARV prophylaxis. These differences by maternal geographical origin have important implications for perinatal HIV transmission prevention, and highlight the validity of disaggregating data by racial/ethnic subgroups. JF - Journal of Immigrant and Minority Health AU - Artstein-McNassar, Melissa AU - Dean, Hazel D AU - Bohannon, Beverly AU - Melville, Sharon K AU - Yeager, Richard AU - Wheeling, John AU - Rose, Charles E AU - Zhu, Julia AU - Dominguez, Kenneth L AD - Centers for Disease Control and Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, 1600 Clifton Road NE, Mailstop E-07, Atlanta, GA, 30333, USA, Washington State University, Pullman, WA, USA ; Centers for Disease Control and Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, 1600 Clifton Road NE, Mailstop E-07, Atlanta, GA, 30333, USA ; Texas Department of State Health Services, Austin, TX, USA ; Texas A & M University—Central Texas, Killeen, TX, USA ; Northrop Grumman Inc., Atlanta, GA, USA ; Myles, Ranell L; Centers for Disease Control and Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, 1600 Clifton Road NE, Mailstop E-07, Atlanta, GA, 30333, USA Y1 - 2015/08// PY - 2015 DA - Aug 2015 SP - 1010 EP - 1018 CY - New York PB - Springer Science & Business Media VL - 17 IS - 4 SN - 1557-1912 KW - Medical Sciences KW - Antenatal care KW - Cohort analysis KW - Perinatal KW - Premature KW - Preventive health care KW - Preventive programmes KW - Sex education KW - Antiretroviral therapy KW - Black people KW - Childbirth KW - Children KW - Cocaine KW - Drug abuse KW - HIV KW - Money KW - Mothers KW - United States--US UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1703894200?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Immigrant+and+Minority+Health&rft.atitle=Perinatal+HIV+Prevention+Outcomes+in+U.S.-Born+Versus+Foreign-Born+Blacks%2C+PSD+Cohort%2C+1995%E2%80%932004&rft.au=Myles%2C+Ranell+L%3BArtstein-McNassar%2C+Melissa%3BDean%2C+Hazel+D%3BBohannon%2C+Beverly%3BMelville%2C+Sharon+K%3BYeager%2C+Richard%3BWheeling%2C+John%3BRose%2C+Charles+E%3BZhu%2C+Julia%3BDominguez%2C+Kenneth+L&rft.aulast=Myles&rft.aufirst=Ranell&rft.date=2015-08-01&rft.volume=17&rft.issue=4&rft.spage=1010&rft.isbn=&rft.btitle=&rft.title=Journal+of+Immigrant+and+Minority+Health&rft.issn=15571912&rft_id=info:doi/10.1007%2Fs10903-014-0034-7 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2015-08-13 N1 - Last updated - 2016-05-16 N1 - SubjectsTermNotLitGenreText - United States--US DO - http://dx.doi.org/10.1007/s10903-014-0034-7 ER - TY - JOUR T1 - A candidate reference measurement procedure for quantifying serum concentrations of 25-hydroxyvitamin D sub(3) and 25-hydroxyvitamin D sub(2) using isotope-dilution liquid chromatography-tandem mass spectrometry AN - 1746892875; PQ0001920593 AB - The inaccuracy of routine serum 25-hydroxyvitamin D measurements hampers the interpretation of data in patient care and public health research. We developed and validated a candidate reference measurement procedure (RMP) for highly accurate quantitation of two clinically important 25-hydroxyvitamin D metabolites in serum, 25-hydroxyvitamin D sub(2) [25(OH)D sub(2)] and 25-hydroxyvitamin D sub(3) [25(OH)D sub(3)]. The two compounds of interest together with spiked deuterium-labeled internal standards [d sub(3)-25(OH)D sub(2) and d sub(6)-25(OH)D sub(3)] were extracted from serum via liquid-liquid extraction. The featured isotope-dilution LC-MS/MS method used reversed-phase chromatography and atmospheric pressure chemical ionization in positive ion mode. A pentafluorophenylpropyl-packed UHPLC column together with isocratic elution allowed for complete baseline resolution of 25(OH)D sub(2) and 25(OH)D sub(3) from their structural C-3 isomers within 12 min. We evaluated method trueness, precision, potential interferences, matrix effects, limits of quantitation, and measurement uncertainty. Calibration materials were, or were traceable to, NIST Standard Reference Materials 2972. Within-day and total imprecision (CV) averaged 1.9 and 2.0 % for 25(OH)D sub(3), respectively, and 2.4 and 3.5 % for 25(OH)D sub(2), respectively. Mean trueness was 100.3 % for 25(OH)D sub(3) and 25(OH)D sub(2). The limits of quantitation/limits of detection were 4.61/1.38 nmol/L for 25(OH)D sub(3) and 1.46/0.13 nmol/L for 25(OH)D sub(2). When we compared our RMP results to an established RMP using 40 serum samples, we found a nonsignificant mean bias of 0.2 % for total 25(OH)D. This candidate RMP for 25(OH)D metabolites meets predefined method performance specifications ( less than or equal to 5 % total CV and less than or equal to 1.7 % bias) and provides sufficient sample throughput to meet the needs of the Centers for Disease Control and Prevention Vitamin D Standardization Certification Program. [Figure not available: see fulltext.] JF - Analytical and Bioanalytical Chemistry AU - Mineva, Ekaterina M AU - Schleicher, Rosemary L AU - Chaudhary-Webb, Madhulika AU - Maw, Khin L AU - Botelho, Julianne C AU - Vesper, Hubert W AU - Pfeiffer, Christine M AD - Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Hwy, NE, Mail Stop F55, Atlanta, GA, 30341, USA, zwa5@cdc.gov PY - 2015 SP - 5615 EP - 5624 PB - Springer Science+Business Media, Berlin/Heidelberg Germany VL - 407 IS - 19 SN - 1618-2642, 1618-2642 KW - Aqualine Abstracts; Water Resources Abstracts KW - Mass Spectrometry KW - Metabolites KW - Atmospheric Pressure KW - Specifications KW - Performance Evaluation KW - Public Health KW - Calibrations KW - Standards KW - Ionization KW - AQ 00001:Water Resources and Supplies KW - SW 5010:Network design UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1746892875?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytical+and+Bioanalytical+Chemistry&rft.atitle=A+candidate+reference+measurement+procedure+for+quantifying+serum+concentrations+of+25-hydroxyvitamin+D+sub%283%29+and+25-hydroxyvitamin+D+sub%282%29+using+isotope-dilution+liquid+chromatography-tandem+mass+spectrometry&rft.au=Mineva%2C+Ekaterina+M%3BSchleicher%2C+Rosemary+L%3BChaudhary-Webb%2C+Madhulika%3BMaw%2C+Khin+L%3BBotelho%2C+Julianne+C%3BVesper%2C+Hubert+W%3BPfeiffer%2C+Christine+M&rft.aulast=Mineva&rft.aufirst=Ekaterina&rft.date=2015-07-01&rft.volume=407&rft.issue=19&rft.spage=5615&rft.isbn=&rft.btitle=&rft.title=Analytical+and+Bioanalytical+Chemistry&rft.issn=16182642&rft_id=info:doi/10.1007%2Fs00216-015-8733-z LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-12-01 N1 - Number of references - 35 N1 - Last updated - 2016-01-21 N1 - SubjectsTermNotLitGenreText - Mass Spectrometry; Performance Evaluation; Public Health; Calibrations; Atmospheric Pressure; Metabolites; Standards; Ionization; Specifications DO - http://dx.doi.org/10.1007/s00216-015-8733-z ER - TY - JOUR T1 - Review of Mass Drug Administration for Malaria and Its Operational Challenges AN - 1722179331; PQ0002060613 AB - Mass drug administration (MDA) was a component of many malaria programs during the eradication era, but later was seldomly deployed due to concerns regarding efficacy and feasibility and fear of accelerating drug resistance. Recently, however, there has been renewed interest in the role of MDA as an elimination tool. Following a 2013 Cochrane Review that focused on the quantitative effects of malaria MDA, we have conducted a systematic, qualitative review of published, unpublished, and gray literature documenting past MDA experiences. We have also consulted with field experts, using their historical experience to provide an informed, contextual perspective on the role of MDA in malaria elimination. Substantial knowledge gaps remain and more research is necessary, particularly on optimal target population size, methods to improve coverage, and primaquine safety. Despite these gaps, MDA has been used successfully to control and eliminate Plasmodium falciparum and P. vivax malaria in the past, and should be considered as part of a comprehensive malaria elimination strategy in specific settings. JF - American Journal of Tropical Medicine and Hygiene AU - Newby, Gretchen AU - Hwang, Jimee AU - Koita, Kadiatou AU - Chen, Ingrid AU - Greenwood, Brian AU - von Seidlein, Lorenz AU - Shanks, G Dennis AU - Slutsker, Laurence AU - Kachur, S Patrick AU - Wegbreit, Jennifer AU - Ippolito, Matthew M AU - Poirot, Eugenie AU - Gosling, Roly AD - The Malaria Elimination Initiative, Global Health Group, University of California, San Francisco, California, gdq1@cdc.gov Y1 - 2015/07// PY - 2015 DA - July 2015 SP - 125 EP - 134 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 93 IS - 1 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts C: Algology, Mycology & Protozoology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Parasites KW - Human diseases KW - Primaquine KW - Fear KW - Drug resistance KW - Malaria KW - Plasmodium falciparum KW - Public health KW - Reviews KW - Hygiene KW - Drugs KW - J 02310:Genetics & Taxonomy KW - Q1 08485:Species interactions: pests and control KW - Q5 08524:Public health, medicines, dangerous organisms KW - K 03310:Genetics & Taxonomy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1722179331?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Review+of+Mass+Drug+Administration+for+Malaria+and+Its+Operational+Challenges&rft.au=Newby%2C+Gretchen%3BHwang%2C+Jimee%3BKoita%2C+Kadiatou%3BChen%2C+Ingrid%3BGreenwood%2C+Brian%3Bvon+Seidlein%2C+Lorenz%3BShanks%2C+G+Dennis%3BSlutsker%2C+Laurence%3BKachur%2C+S+Patrick%3BWegbreit%2C+Jennifer%3BIppolito%2C+Matthew+M%3BPoirot%2C+Eugenie%3BGosling%2C+Roly&rft.aulast=Newby&rft.aufirst=Gretchen&rft.date=2015-07-01&rft.volume=93&rft.issue=1&rft.spage=125&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0254 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-02-04 N1 - SubjectsTermNotLitGenreText - Parasites; Human diseases; Drug resistance; Malaria; Hygiene; Drugs; Public health; Primaquine; Fear; Reviews; Plasmodium falciparum DO - http://dx.doi.org/10.4269/ajtmh.14-0254 ER - TY - JOUR T1 - Human Granulocytic Anaplasmosis in the United States from 2008 to 2012: A Summary of National Surveillance Data AN - 1722168429; PQ0002060603 AB - Human granulocytic anaplasmosis is an acute, febrile illness transmitted by the ticks Ixodes scapularls and Ixodes pacificus In the United States. We present a summary of passive surveillance data for cases of anaplasmosis with onset during 2008-2012. The overall reported incidence rate (IR) was 6.3 cases per million person-years. Cases were reported from 38 states and from New York City, with the highest incidence in Minnesota (IR = 97), Wisconsin (IR = 79), and Rhode Island (IR = 51). Thirty-seven percent of cases were classified as confirmed, almost exclusively by polymerase chain reaction. The reported case fatality rate was 0.3% and the reported hospitalization rate was 31%. IRs, hospitalization rates, life-threatening complications, and case fatality rates increased with age group. The IR increased from 2008 to 2012 and the geographic range of reported cases of anaplasmosis appears to have increased since 2000-2007. Our findings are consistent with previous case series and recent reports of the expanding range of the tick vector I. scapularis. JF - American Journal of Tropical Medicine and Hygiene AU - Dahlgren, F Scott AU - Heitman, Kristen Nichols AU - Drexler, Naomi A AU - Massung, Robert F AU - Behravesh, Casey Barton AD - Rickettsial Zoonoses Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, iot0@cdc.gov Y1 - 2015/07// PY - 2015 DA - July 2015 SP - 66 EP - 72 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 93 IS - 1 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology KW - Ixodes KW - Age KW - Anaplasmosis KW - Data processing KW - Ixodidae KW - Vectors KW - Polymerase chain reaction KW - Ixodes pacificus KW - K 03400:Human Diseases KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1722168429?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Human+Granulocytic+Anaplasmosis+in+the+United+States+from+2008+to+2012%3A+A+Summary+of+National+Surveillance+Data&rft.au=Dahlgren%2C+F+Scott%3BHeitman%2C+Kristen+Nichols%3BDrexler%2C+Naomi+A%3BMassung%2C+Robert+F%3BBehravesh%2C+Casey+Barton&rft.aulast=Dahlgren&rft.aufirst=F&rft.date=2015-07-01&rft.volume=46&rft.issue=3S1&rft.spage=S59&rft.isbn=&rft.btitle=&rft.title=Journal+of+Adolescent+Health&rft.issn=1054139X&rft_id=info:doi/10.1016%2Fj.jadohealth.2009.11.218 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Age; Data processing; Anaplasmosis; Polymerase chain reaction; Vectors; Ixodes; Ixodidae; Ixodes pacificus DO - http://dx.doi.org/10.4269/ajtmh.15-0122 ER - TY - JOUR T1 - Increasing Prevalence of a Novel Triple-Mutant Dihydropteroate Synthase Genotype in Plasmodium falciparum in Western Kenya AN - 1701494937; PQ0001784623 AB - The molecular basis of sulfadoxine-pyrimethamine (SP) resistance lies in a combination of single-nucleotide polymorphisms (SNPs) in two genes coding for Plasmodium falciparum dihydrofolate reductase (Pfdhfr) and P. falciparum dihydropteroate synthase (Pfdhps), targeted by pyrimethamine and sulfadoxine, respectively. The continued use of SP for intermittent preventive treatment in pregnant women in many African countries, despite SP's discontinuation as a first-line antimalarial treatment option due to high levels of drug resistance, may further increase the prevalence of SP-resistant parasites and/or lead to the selection of new mutations. An antimalarial drug resistance surveillance study was conducted in western Kenya between 2010 and 2013. A total of 203 clinical samples from children with uncomplicated malaria were genotyped for SNPs associated with SP resistance. The prevalence of the triple-mutant Pfdhfr C50I51R59N108I164 genotype and the double-mutant Pfdhps S436G437E540A581A613 genotype was high. Two triple-mutant Pfdhps genotypes, S436G437E540G581A613 and H436G437E540A581A613, were found, with the latter thus far being uniquely found in western Kenya. The prevalence of the S436G437E540G581A613 genotype was low. However, a steady increase in the prevalence of the Pfdhps triple-mutant H436G437E540A581A613 genotype has been observed since its appearance in early 2000. Isolates with these genotypes shared substantial microsatellite haplotypes with the most common double-mutant allele, suggesting that this triple-mutant allele may have evolved locally. Overall, these findings show that the prevalence of the H436G437E540A581A613 triple mutant may be increasing in this population and could compromise the efficacy of SP for intermittent preventive treatment in pregnant women if it increases the resistance threshold further. JF - Antimicrobial Agents & Chemotherapy AU - Lucchi, Naomi W AU - Okoth, Sheila Akinyi AU - Komino, Franklin AU - Onyona, Philip AU - Goldman, Ira F AU - Ljolje, Dragan AU - Shi, Ya Ping AU - Barnwell, John W AU - Udhayakumar, Venkatachalam AU - Kariuki, Simon AD - Malaria Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, NLucchi@cdc.gov. Y1 - 2015/07// PY - 2015 DA - July 2015 SP - 3995 EP - 4002 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 59 IS - 7 SN - 0066-4804, 0066-4804 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Pyrimethamine KW - Parasites KW - Allelles KW - Drug resistance KW - Malaria KW - Genotypes KW - Public health KW - Population genetics KW - Kenya KW - Dihydrofolate reductase KW - Haplotypes KW - Antimalarial agents KW - Mutations KW - Microsatellites KW - Plasmodium falciparum KW - Children KW - Sulfadoxine KW - Biopolymorphism KW - Dihydropteroate synthase KW - Substance P KW - Pregnancy KW - Single-nucleotide polymorphism KW - Africa KW - Mutation KW - New species KW - A 01340:Antibiotics & Antimicrobials KW - K 03400:Human Diseases KW - Q1 08604:Stock assessment and management KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1701494937?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Increasing+Prevalence+of+a+Novel+Triple-Mutant+Dihydropteroate+Synthase+Genotype+in+Plasmodium+falciparum+in+Western+Kenya&rft.au=Lucchi%2C+Naomi+W%3BOkoth%2C+Sheila+Akinyi%3BKomino%2C+Franklin%3BOnyona%2C+Philip%3BGoldman%2C+Ira+F%3BLjolje%2C+Dragan%3BShi%2C+Ya+Ping%3BBarnwell%2C+John+W%3BUdhayakumar%2C+Venkatachalam%3BKariuki%2C+Simon&rft.aulast=Lucchi&rft.aufirst=Naomi&rft.date=2015-07-01&rft.volume=59&rft.issue=7&rft.spage=3995&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.04961-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-08-01 N1 - Number of references - 39 N1 - Last updated - 2016-02-04 N1 - SubjectsTermNotLitGenreText - Population genetics; Parasites; Mutations; Allelles; Drug resistance; Genotypes; Biopolymorphism; Public health; New species; Pyrimethamine; Microsatellites; Malaria; Sulfadoxine; Children; Dihydropteroate synthase; Substance P; Pregnancy; Dihydrofolate reductase; Haplotypes; Single-nucleotide polymorphism; Antimalarial agents; Mutation; Plasmodium falciparum; Kenya; Africa DO - http://dx.doi.org/10.1128/AAC.04961-14 ER - TY - CPAPER T1 - Giardiasis Outbreaks Associated with All Modes of Transmission--United States, 1971-2011 T2 - 2015 American Water Works Association Annual Conference & Exposition (ACE 2015) AN - 1658697526; 6335518 JF - 2015 American Water Works Association Annual Conference & Exposition (ACE 2015) AU - Adam, Elizabeth Y1 - 2015/06/07/ PY - 2015 DA - 2015 Jun 07 KW - Giardiasis KW - Outbreaks UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1658697526?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2015+American+Water+Works+Association+Annual+Conference+%26+Exposition+%28ACE+2015%29&rft.atitle=Giardiasis+Outbreaks+Associated+with+All+Modes+of+Transmission--United+States%2C+1971-2011&rft.au=Adam%2C+Elizabeth&rft.aulast=Adam&rft.aufirst=Elizabeth&rft.date=2015-06-07&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2015+American+Water+Works+Association+Annual+Conference+%26+Exposition+%28ACE+2015%29&rft.issn=&rft_id=info:doi/ L2 - http://www.awwa.org/conferences-education/conferences/annual-conference/ace15-professional-program.aspx LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-02-28 N1 - Last updated - 2015-02-27 ER - TY - JOUR T1 - Evaluation of Point-of-Contact Circulating Cathodic Antigen Assays for the Detection of Schistosoma mansoni Infection in Low-, Moderate-, and High-Prevalence Schools in Western Kenya AN - 1727697670; PQ0002136536 AB - We evaluated the performance of a point-of-contact circulating cathodic antigen assay (POC-CCA) to detect schistosome infections in primary school children (N = 1,801) living in areas with low, moderate, and high Schistosoma mansoni prevalence in western Kenya. The commercially available assay (CCA-1) and a second, experimental formulation (CCA-2) were compared against Kato-Katz stool examinations and an anti-schistosome enzyme-linked immunosorbent assay (ELISA). A latent class model based on the four tests was used to establish "true infection status" in three different zones based on their distance from Lake Victoria. As a screening tool for community treatment according to World Health Organization (WHO) guidelines, the Kato-Katz examination was in closest agreement with the latent class model, followed by the experimental CCA-2, soluble adult worm antigen preparation (SWAP) ELISA, and CCA-1, which had high sensitivity compared with the other tests but was consistently the least specific. Our experience suggests that POC-CCA tests offer a field-friendly alternative to Kato-Katz, but need further Interpretation for appropriate field use. JF - American Journal of Tropical Medicine and Hygiene AU - Foo, Karen T AU - Blackstock, Anna J AU - Ochola, Elizabeth A AU - Matete, Daniel O AU - Mwinzi, Pauline N M AU - Montgomery, Susan P AU - Karanja, Diana M S AU - Secor, W Evan AD - Department of Public Health Sciences, Division of Global Health/IHCAR, Karolinska Institute, Stockholm, Sweden, was4@cdc.gov Y1 - 2015/06// PY - 2015 DA - June 2015 SP - 1227 EP - 1232 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 92 IS - 6 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Schistosoma mansoni KW - Screening KW - Parasites KW - Enzyme-linked immunosorbent assay KW - Disease control KW - Schistosomiasis KW - Infection KW - Children KW - Education establishments KW - Models KW - Public health KW - Africa, Victoria L. KW - Lakes KW - Antigens KW - ELISA KW - Feces KW - Hygiene KW - K 03400:Human Diseases KW - Q1 08484:Species interactions: parasites and diseases KW - J 02400:Human Diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727697670?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Evaluation+of+Point-of-Contact+Circulating+Cathodic+Antigen+Assays+for+the+Detection+of+Schistosoma+mansoni+Infection+in+Low-%2C+Moderate-%2C+and+High-Prevalence+Schools+in+Western+Kenya&rft.au=Foo%2C+Karen+T%3BBlackstock%2C+Anna+J%3BOchola%2C+Elizabeth+A%3BMatete%2C+Daniel+O%3BMwinzi%2C+Pauline+N+M%3BMontgomery%2C+Susan+P%3BKaranja%2C+Diana+M+S%3BSecor%2C+W+Evan&rft.aulast=Foo&rft.aufirst=Karen&rft.date=2015-06-01&rft.volume=92&rft.issue=6&rft.spage=1227&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0643 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-04-29 N1 - SubjectsTermNotLitGenreText - Screening; Parasites; Antigens; Disease control; Schistosomiasis; ELISA; Hygiene; Education establishments; Public health; Lakes; Enzyme-linked immunosorbent assay; Children; Feces; Infection; Models; Schistosoma mansoni; Africa, Victoria L. DO - http://dx.doi.org/10.4269/ajtmh.14-0643 ER - TY - JOUR T1 - Cost Analysis of Tests for the Detection of Schistosoma mansoni Infection in Children in Western Kenya AN - 1727696140; PQ0002136537 AB - Financial resources tend to be limited in schistosomiasis endemic areas, forcing program managers to balance financial and scientific considerations when selecting detection assays. Therefore, we compared the costs of using single stool Kato-Katz, triplicate stool Kato-Katz, and point-of-contact circulating cathodic antigen (POC-CCA) assays for the detection of Schistosoma mansoni infection. Economic and financial costs were estimated from the viewpoint of a schistosomiasis control program using the ingredients approach. Costs related to specimen collection, sample processing and analysis, and treatment delivery were considered. Analysis inputs and assumptions were tested using one-way and two-way sensitivity analysis. The total per-person cost of performing the single Kato-Katz, triplicate Kato-Katz, and POC-CCA was US$6.89, US$17.54, and US$ 7.26, respectively. Major cost drivers included labor, transportation, and supplies. In addition, we provide a costing tool to guide program managers in evaluating detection costs in specific settings, as costs may vary temporally and spatially. JF - American Journal of Tropical Medicine and Hygiene AU - Worrell, Caitlin M AU - Bartoces, Monina AU - Karanja, Diana M S AU - Ochola, Elizabeth A AU - Matete, Daniel O AU - Mwinzi, Pauline N M AU - Montgomery, Susan P AU - Secor, W Evan AD - Parasitic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, was4@cdc.gov Y1 - 2015/06// PY - 2015 DA - June 2015 SP - 1233 EP - 1239 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 92 IS - 6 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Schistosoma mansoni KW - Parasites KW - Control programs KW - Financial management KW - Disease control KW - Schistosomiasis KW - Infection KW - Children KW - Financial resources KW - Public health KW - Endemic species KW - Kenya KW - Antigens KW - Economics KW - Feces KW - Hygiene KW - K 03400:Human Diseases KW - J 02400:Human Diseases KW - Q1 08604:Stock assessment and management KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727696140?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Cost+Analysis+of+Tests+for+the+Detection+of+Schistosoma+mansoni+Infection+in+Children+in+Western+Kenya&rft.au=Worrell%2C+Caitlin+M%3BBartoces%2C+Monina%3BKaranja%2C+Diana+M+S%3BOchola%2C+Elizabeth+A%3BMatete%2C+Daniel+O%3BMwinzi%2C+Pauline+N+M%3BMontgomery%2C+Susan+P%3BSecor%2C+W+Evan&rft.aulast=Worrell&rft.aufirst=Caitlin&rft.date=2015-06-01&rft.volume=92&rft.issue=6&rft.spage=1233&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0644 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Parasites; Endemic species; Antigens; Financial management; Disease control; Schistosomiasis; Hygiene; Financial resources; Public health; Control programs; Economics; Children; Feces; Infection; Schistosoma mansoni; Kenya DO - http://dx.doi.org/10.4269/ajtmh.14-0644 ER - TY - JOUR T1 - Serological Investigation of Heartland Virus (Bunyaviridae: Phlebovirus) Exposure in Wild and Domestic Animals Adjacent to Human Case Sites in Missouri 2012-2013 AN - 1727695514; PQ0002136526 AB - Heartland virus (HRTV; Bunyaviridae: Phlebovirus) has recently emerged as a causative agent of human disease characterized by thrombocytopenia and leukopenia in the United States. The lone star tick (Amblyomma americanum L.) has been implicated as a vector. To identify candidate vertebrate amplification hosts associated with enzootic maintenance of the virus, sera and ticks were sampled from 160 mammals (8 species) and 139 birds (26 species) captured near 2 human case residences in Andrew and Nodaway Counties in northwest Missouri. HRTV-specific neutralizing antibodies were identified in northern raccoons (42.6%), horses (17.4%), white-tailed deer (14.3%), dogs (7.7%), and Virginia opossums (3.8%), but not in birds. Virus isolation attempts from sera and ticks failed to detect HRTV. The high antibody prevalence coupled with local abundance of white-tailed deer and raccoons identifies these species as candidate amplification hosts. JF - American Journal of Tropical Medicine and Hygiene AU - Bosco-Lauth, Angela M AU - Panella, Nicholas A AU - Root, J Jeffrey AU - Gidlewski, Tom AU - Lash, R Ryan AU - Harmon, Jessica R AU - Burkhalter, Kristen L AU - Godsey, Marvin S AU - Savage, Harry M AU - Nicholson, William L AU - Komar, Nicholas AU - Brault, Aaron C AD - Division of Vector-Borne Diseases, Arboviral Diseases Branch, Centers for Disease Control and Prevention, Fort Collins, Colorado, abrault@cdc.gov Y1 - 2015/06// PY - 2015 DA - June 2015 SP - 1163 EP - 1167 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 92 IS - 6 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Heart KW - Human diseases KW - Ixodidae KW - Abundance KW - Vectors KW - Hosts KW - Phlebovirus KW - ANW, USA, Virginia KW - Bunyaviridae KW - Disease transmission KW - Amblyomma americanum KW - Domestic animals KW - Antibodies KW - Thrombocytopenia KW - USA, Missouri KW - Leukopenia KW - Hygiene KW - K 03410:Animal Diseases KW - J 02410:Animal Diseases KW - V 22410:Animal Diseases KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727695514?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Serological+Investigation+of+Heartland+Virus+%28Bunyaviridae%3A+Phlebovirus%29+Exposure+in+Wild+and+Domestic+Animals+Adjacent+to+Human+Case+Sites+in+Missouri+2012-2013&rft.au=Bosco-Lauth%2C+Angela+M%3BPanella%2C+Nicholas+A%3BRoot%2C+J+Jeffrey%3BGidlewski%2C+Tom%3BLash%2C+R+Ryan%3BHarmon%2C+Jessica+R%3BBurkhalter%2C+Kristen+L%3BGodsey%2C+Marvin+S%3BSavage%2C+Harry+M%3BNicholson%2C+William+L%3BKomar%2C+Nicholas%3BBrault%2C+Aaron+C&rft.aulast=Bosco-Lauth&rft.aufirst=Angela&rft.date=2015-06-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Human diseases; Antibodies; Hosts; Hygiene; Disease transmission; Heart; Domestic animals; Thrombocytopenia; Abundance; Vectors; Leukopenia; Amblyomma americanum; Ixodidae; Phlebovirus; Bunyaviridae; USA, Missouri; ANW, USA, Virginia DO - http://dx.doi.org/10.4269/ajtmh.14-0702 ER - TY - JOUR T1 - Evaluation of Level of Agreement in Bordetella Species Identification in Three U.S. Laboratories during a Period of Increased Pertussis AN - 1709175558; PQ0001679729 AB - While PCR is the most common method used for detecting Bordetella pertussis in the United States, most laboratories use insertion sequence 481 (IS481), which is not specific for B. pertussis; therefore, the relative contribution of other Bordetella species is not understood. The objectives of this study were to evaluate the proportion of other Bordetella species misidentified as B. pertussis during a period of increased pertussis incidence, determine the level of agreement in Bordetella species detection between U.S. commercial laboratories and the CDC, and assess the relative diagnostic sensitivity of CDC's PCR assay when using a different PCR master mix. Specimens collected between May 2012 and May 2013 were tested at two U.S. commercial laboratories for B. pertussis and B. parapertussis detection. Every fifth specimen positive for IS481 and/or IS1001 with cycle threshold (CT) values of less than or equal to 35 was sent to CDC for PCR testing that identifies Bordetella species. Specimens with indeterminate or negative results in the CDC PCR were tested using an alternate PCR master mix. Of 755 specimens, there was agreement in species identification for 83.4% (n = 630). Of the specimens with different identifications (n = 125), 79.2% (n = 99) were identified as indeterminate B. pertussis at CDC. Overall, 0.66% (n = 5) of the specimens were identified as B. holmesii or B. bronchiseptica at CDC. Of 115 specimens with indeterminate or negative results, 46.1% (n = 53) were B. pertussis positive when tested by an alternate master mix, suggesting a possible increase in assay sensitivity. This study demonstrates good agreement between the two U.S. commercial laboratories and CDC and little misidentification of Bordetella species during the 2012 U.S. epidemic. JF - Journal of Clinical Microbiology AU - Burgos-Rivera, Brunilis AU - Lee, Adria D AU - Bowden, Katherine E AU - Faulkner, Amanda E AU - Seaton, Brent L AU - Lembke, Bryndon D AU - Cartwright, Charles P AU - Martin, Stacey W AU - Tondella, M Lucia AD - Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Atlanta, Georgia, USA, wri2@cdc.gov. Y1 - 2015/06// PY - 2015 DA - June 2015 SP - 1842 EP - 1847 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 53 IS - 6 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Pertussis KW - Bordetella pertussis KW - Epidemics KW - Bordetella KW - Polymerase chain reaction KW - Insertion sequences KW - J 02300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1709175558?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Evaluation+of+Level+of+Agreement+in+Bordetella+Species+Identification+in+Three+U.S.+Laboratories+during+a+Period+of+Increased+Pertussis&rft.au=Burgos-Rivera%2C+Brunilis%3BLee%2C+Adria+D%3BBowden%2C+Katherine+E%3BFaulkner%2C+Amanda+E%3BSeaton%2C+Brent+L%3BLembke%2C+Bryndon+D%3BCartwright%2C+Charles+P%3BMartin%2C+Stacey+W%3BTondella%2C+M+Lucia&rft.aulast=Burgos-Rivera&rft.aufirst=Brunilis&rft.date=2015-06-01&rft.volume=53&rft.issue=6&rft.spage=1842&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.03567-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-09-01 N1 - Number of references - 30 N1 - Last updated - 2016-07-20 N1 - SubjectsTermNotLitGenreText - Pertussis; Epidemics; Polymerase chain reaction; Insertion sequences; Bordetella pertussis; Bordetella DO - http://dx.doi.org/10.1128/JCM.03567-14 ER - TY - JOUR T1 - Epidemiology of drug-resistant tuberculosis among children and adolescents in South Africa, 2005-2010 AN - 1694984304; PQ0001662589 AB - OBJECTIVE: To describe the demographic and clinical characteristics of children and adolescents diagnosed with resistance to any anti-tuberculosis drug (drug-resistant tuberculosis; DR-TB) in South Africa. DESIGN: We retrospectively reviewed medical records of all children (<13 years) and adolescents (13 to <18 years) with DR-TB at specialty hospitals in four South African provinces from 2005 to 2010. RESULTS: During the review period, 774 children and adolescents (median age 11.3 years) were diagnosed with DR-TB at selected facilities. A high proportion of patients had a history of previous TB treatment (285/631; 45.2%), human immunodeficiency virus (HIV) infection (375/685; 54.7%), contact with a TB case (347/454; 76.4%), and smear-positive (443/729; 60.8%), cavitary (253/680, 38.7%) disease. Eighty-two per cent of patients with HTV infection received antiretroviral therapy. Of 626 patients diagnosed with multidrug-resistant TB (MDR-TB), 561 (89.6%) received a regimen consistent with national guidelines; the median length of treatment was 22 months (IQR 16-25). Among 400 patients with any DR-TB and a known outcome, 20.3% died during treatment. CONCLUSION: Pediatric DR-TB in these provinces is characterized by complex clinical features at diagnosis, with one in five children dying during treatment. History of previous treatment and contact with a TB patient indicate opportunities for earlier diagnosis and treatment to improve outcomes. JF - International Journal of Tuberculosis and Lung Disease AU - Moore, B K AU - Anyalechi, E AU - van der Walt, M AU - Smith, S AU - Erasmus, L AU - Lancaster, J AU - Morris, S AU - Ndjeka, N AU - Ershova, J AU - Ismail, N AU - Burton, D AU - Menzies, H AD - Centers for Disease Control and Prevention, MS-E99,1600 Clifton Rd, Atlanta, GA, 30329, USA, bkmoore@cdc.gov Y1 - 2015/06// PY - 2015 DA - Jun 2015 SP - 663 EP - 669 PB - International Union Against Tuberculosis and Lung Disease, 68 bvd Saint-Michel Paris 75006 France VL - 19 IS - 6 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts KW - South Africa KW - drug resistance KW - pediatric KW - cohort review KW - Mycobacterium tuberculosis KW - Historical account KW - Age KW - Mycobacterium KW - Drug resistance KW - Infection KW - Demography KW - Tuberculosis KW - Adolescents KW - Pediatrics KW - medical records KW - Adolescence KW - Guidelines KW - antiretroviral therapy KW - Lung diseases KW - Children KW - Antiretroviral agents KW - Epidemiology KW - Lung KW - Human immunodeficiency virus KW - Reviews KW - Hospitals KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1694984304?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Epidemiology+of+drug-resistant+tuberculosis+among+children+and+adolescents+in+South+Africa%2C+2005-2010&rft.au=Moore%2C+B+K%3BAnyalechi%2C+E%3Bvan+der+Walt%2C+M%3BSmith%2C+S%3BErasmus%2C+L%3BLancaster%2C+J%3BMorris%2C+S%3BNdjeka%2C+N%3BErshova%2C+J%3BIsmail%2C+N%3BBurton%2C+D%3BMenzies%2C+H&rft.aulast=Moore&rft.aufirst=B&rft.date=2015-06-01&rft.volume=19&rft.issue=6&rft.spage=663&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/10.5588%2Fijtld.14.0879 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-07-01 N1 - Last updated - 2015-08-05 N1 - SubjectsTermNotLitGenreText - Age; medical records; Pediatrics; Adolescence; Drug resistance; antiretroviral therapy; Lung diseases; Children; Infection; Demography; Epidemiology; Tuberculosis; Hospitals; Historical account; Guidelines; Antiretroviral agents; Human immunodeficiency virus; Lung; Reviews; Adolescents; Mycobacterium; South Africa DO - http://dx.doi.org/10.5588/ijtld.14.0879 ER - TY - JOUR T1 - Acetyl Fentanyl, a Novel Fentanyl Analog, Causes 14 Overdose Deaths in Rhode Island, March-May 2013. AN - 1689844154; 25934111 JF - Journal of medical toxicology : official journal of the American College of Medical Toxicology AU - Lozier, Matthew J AU - Boyd, Molly AU - Stanley, Christina AU - Ogilvie, Laurie AU - King, Ewa AU - Martin, Colleen AU - Lewis, Lauren AD - Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA, mlozier@cdc.gov. Y1 - 2015/06// PY - 2015 DA - June 2015 SP - 208 EP - 217 VL - 11 IS - 2 KW - Analgesics, Opioid KW - 0 KW - N-(1-phenethylpiperidin-4-yl)-N-phenylacetamide KW - 6DZ28538KS KW - Fentanyl KW - UF599785JZ KW - Index Medicus KW - Young Adult KW - Humans KW - Aged KW - Drug Overdose -- epidemiology KW - Socioeconomic Factors KW - Needles KW - Risk Factors KW - Adult KW - Databases, Factual KW - Gas Chromatography-Mass Spectrometry KW - Enzyme-Linked Immunosorbent Assay KW - Rhode Island -- epidemiology KW - Middle Aged KW - Female KW - Male KW - Analgesics, Opioid -- poisoning KW - Analgesics, Opioid -- analysis KW - Fentanyl -- poisoning KW - Fentanyl -- analogs & derivatives KW - Fentanyl -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1689844154?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+medical+toxicology+%3A+official+journal+of+the+American+College+of+Medical+Toxicology&rft.atitle=Acetyl+Fentanyl%2C+a+Novel+Fentanyl+Analog%2C+Causes+14+Overdose+Deaths+in+Rhode+Island%2C+March-May+2013.&rft.au=Lozier%2C+Matthew+J%3BBoyd%2C+Molly%3BStanley%2C+Christina%3BOgilvie%2C+Laurie%3BKing%2C+Ewa%3BMartin%2C+Colleen%3BLewis%2C+Lauren&rft.aulast=Lozier&rft.aufirst=Matthew&rft.date=2015-06-01&rft.volume=11&rft.issue=2&rft.spage=208&rft.isbn=&rft.btitle=&rft.title=Journal+of+medical+toxicology+%3A+official+journal+of+the+American+College+of+Medical+Toxicology&rft.issn=1937-6995&rft_id=info:doi/10.1007%2Fs13181-015-0477-9 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2016-03-22 N1 - Date created - 2015-06-17 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Cited By: J Urban Health. 2005 Jun;82(2):303-11 [15872192] Drug Alcohol Depend. 2005 Aug 1;79(2):181-90 [16002027] Addiction. 2008 Jun;103(6):979-89 [18422830] MMWR Morb Mortal Wkly Rep. 2008 Jul 25;57(29):793-6 [18650786] NCHS Data Brief. 2009 Sep;(22):1-8 [19796521] Med Health R I. 2011 Aug;94(8):240-2 [21913619] MMWR Morb Mortal Wkly Rep. 2011 Nov 4;60(43):1487-92 [22048730] Pain Physician. 2012 Jul;15(3 Suppl):ES9-38 [22786464] BMJ. 2013;346:f174 [23372174] JAMA. 2013 Feb 20;309(7):657-9 [23423407] Drug Alcohol Depend. 2013 Sep 1;132(1-2):95-100 [23410617] MMWR Morb Mortal Wkly Rep. 2013 Aug 30;62(34):703-4 [23985500] Anal Chem. 2014 Feb 4;86(3):1760-6 [24354295] Ann Emerg Med. 2014 Dec;64(6):637-9 [25153008] J Forensic Sci. 1974 Jan;19(1):155-62 [4853734] J Psychoactive Drugs. 1981 Jan-Mar;13(1):91-3 [7277090] Anal Chem. 1981 Oct;53(12):1379A-1386A [7294353] Med Res Rev. 1986 Jan-Mar;6(1):41-74 [3512935] JAMA. 1991 Feb 27;265(8):1011-3 [1867667] Ann Emerg Med. 1991 Feb;20(2):158-64 [1996799] JAMA. 1991 Jun 12;265(22):2962 [2033766] Subst Use Misuse. 1997 Jan;32(2):195-201 [9044547] Addiction. 2005 Mar;100(3):397-404 [15733253] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1007/s13181-015-0477-9 ER - TY - CPAPER T1 - Overview of CDC's vision for IQCP T2 - 115th General Meeting of the American Society for Microbiology (ASM 2015) AN - 1658699033; 6336208 JF - 115th General Meeting of the American Society for Microbiology (ASM 2015) AU - Anderson, Nancy Y1 - 2015/05/30/ PY - 2015 DA - 2015 May 30 KW - Vision KW - Reviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1658699033?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=115th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2015%29&rft.atitle=Overview+of+CDC%27s+vision+for+IQCP&rft.au=Anderson%2C+Nancy&rft.aulast=Anderson&rft.aufirst=Nancy&rft.date=2015-05-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=115th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2015%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/start.aspx?mkey={224BAD71-94EA-4FA5-8DF3-F4087BDC3625} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-02-28 N1 - Last updated - 2015-02-27 ER - TY - CPAPER T1 - The Final Recommendations T2 - 115th General Meeting of the American Society for Microbiology (ASM 2015) AN - 1658699004; 6336125 JF - 115th General Meeting of the American Society for Microbiology (ASM 2015) AU - Cornish, Nancy Y1 - 2015/05/30/ PY - 2015 DA - 2015 May 30 KW - Microbiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1658699004?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=115th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2015%29&rft.atitle=The+Final+Recommendations&rft.au=Cornish%2C+Nancy&rft.aulast=Cornish&rft.aufirst=Nancy&rft.date=2015-05-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=115th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2015%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/start.aspx?mkey={224BAD71-94EA-4FA5-8DF3-F4087BDC3625} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-02-28 N1 - Last updated - 2015-02-27 ER - TY - CPAPER T1 - Dissemination and Implementation of the Recommendations: A CDC Approach T2 - 115th General Meeting of the American Society for Microbiology (ASM 2015) AN - 1658698987; 6336126 JF - 115th General Meeting of the American Society for Microbiology (ASM 2015) AU - Weirich, Elizabeth Y1 - 2015/05/30/ PY - 2015 DA - 2015 May 30 KW - Microbiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1658698987?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=115th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2015%29&rft.atitle=Dissemination+and+Implementation+of+the+Recommendations%3A+A+CDC+Approach&rft.au=Weirich%2C+Elizabeth&rft.aulast=Weirich&rft.aufirst=Elizabeth&rft.date=2015-05-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=115th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2015%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/start.aspx?mkey={224BAD71-94EA-4FA5-8DF3-F4087BDC3625} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-02-28 N1 - Last updated - 2015-02-27 ER - TY - CPAPER T1 - The Intriguing Relationship Between Malaria and Sickle Cell Disease T2 - 115th General Meeting of the American Society for Microbiology (ASM 2015) AN - 1658698844; 6336119 JF - 115th General Meeting of the American Society for Microbiology (ASM 2015) AU - Gutman, Julie Y1 - 2015/05/30/ PY - 2015 DA - 2015 May 30 KW - Malaria KW - Sickle cell disease KW - Public health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1658698844?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=115th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2015%29&rft.atitle=The+Intriguing+Relationship+Between+Malaria+and+Sickle+Cell+Disease&rft.au=Gutman%2C+Julie&rft.aulast=Gutman&rft.aufirst=Julie&rft.date=2015-05-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=115th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2015%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/start.aspx?mkey={224BAD71-94EA-4FA5-8DF3-F4087BDC3625} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-02-28 N1 - Last updated - 2015-02-27 ER - TY - CPAPER T1 - Epidemiology, Early Diagnosis and Treatment of Infection in Thalassemia Patients T2 - 115th General Meeting of the American Society for Microbiology (ASM 2015) AN - 1658698792; 6336117 JF - 115th General Meeting of the American Society for Microbiology (ASM 2015) AU - Grant, Althea Y1 - 2015/05/30/ PY - 2015 DA - 2015 May 30 KW - Epidemiology KW - Disease control KW - Infection KW - Thalassemia UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1658698792?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=115th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2015%29&rft.atitle=Epidemiology%2C+Early+Diagnosis+and+Treatment+of+Infection+in+Thalassemia+Patients&rft.au=Grant%2C+Althea&rft.aulast=Grant&rft.aufirst=Althea&rft.date=2015-05-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=115th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2015%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/start.aspx?mkey={224BAD71-94EA-4FA5-8DF3-F4087BDC3625} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-02-28 N1 - Last updated - 2015-02-27 ER - TY - CPAPER T1 - Population Based Invasive Pneumococcal Strain Distributions in the US during Pre and Post 13 Valent Conjugate Vaccine Periods T2 - 115th General Meeting of the American Society for Microbiology (ASM 2015) AN - 1658698575; 6336186 JF - 115th General Meeting of the American Society for Microbiology (ASM 2015) AU - Beall, Bernard Y1 - 2015/05/30/ PY - 2015 DA - 2015 May 30 KW - Disease control KW - Vaccines KW - Strains KW - Streptococcus pneumoniae UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1658698575?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=115th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2015%29&rft.atitle=Population+Based+Invasive+Pneumococcal+Strain+Distributions+in+the+US+during+Pre+and+Post+13+Valent+Conjugate+Vaccine+Periods&rft.au=Seward%2C+Jane&rft.aulast=Seward&rft.aufirst=Jane&rft.date=2011-09-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=51st+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/start.aspx?mkey={224BAD71-94EA-4FA5-8DF3-F4087BDC3625} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-02-28 N1 - Last updated - 2015-02-27 ER - TY - CPAPER T1 - Toxocariasis T2 - 115th General Meeting of the American Society for Microbiology (ASM 2015) AN - 1658697563; 6336058 JF - 115th General Meeting of the American Society for Microbiology (ASM 2015) AU - Abanyie, Francisca Y1 - 2015/05/30/ PY - 2015 DA - 2015 May 30 KW - Toxocariasis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1658697563?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=115th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2015%29&rft.atitle=Toxocariasis&rft.au=Abanyie%2C+Francisca&rft.aulast=Abanyie&rft.aufirst=Francisca&rft.date=2015-05-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=115th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2015%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/start.aspx?mkey={224BAD71-94EA-4FA5-8DF3-F4087BDC3625} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-02-28 N1 - Last updated - 2015-02-27 ER - TY - CPAPER T1 - Acoustic requirements for audiometric testing and hearing protector fit-testing with mobile platforms T2 - 169th Meeting of the Acoustical Society of America AN - 1669822070; 6341646 JF - 169th Meeting of the Acoustical Society of America AU - Murphy, William Y1 - 2015/05/18/ PY - 2015 DA - 2015 May 18 KW - Acoustics KW - Mobile platforms KW - Hearing UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1669822070?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=169th+Meeting+of+the+Acoustical+Society+of+America&rft.atitle=Acoustic+requirements+for+audiometric+testing+and+hearing+protector+fit-testing+with+mobile+platforms&rft.au=Murphy%2C+William&rft.aulast=Murphy&rft.aufirst=William&rft.date=2015-05-18&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=169th+Meeting+of+the+Acoustical+Society+of+America&rft.issn=&rft_id=info:doi/ L2 - https://asa2015spring.abstractcentral.com/planner.jsp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-31 N1 - Last updated - 2015-04-06 ER - TY - JOUR T1 - Numerical modeling of water spray suppression of conveyor belt fires in a large-scale tunnel AN - 1746887641; PQ0001936446 AB - Conveyor belt fires in an underground mine pose a serious life threat to miners. Water sprinkler systems are usually used to extinguish underground conveyor belt fires, but because of the complex interaction between conveyor belt fires and mine ventilation airflow, more effective engineering designs are needed for the installation of water sprinkler systems. A computational fluid dynamics (CFD) model was developed to simulate the interaction between the ventilation airflow, the belt flame spread, and the water spray system in a mine entry. The CFD model was calibrated using test results from a large-scale conveyor belt fire suppression experiment. Simulations were conducted using the calibrated CFD model to investigate the effects of sprinkler location, water flow rate, and sprinkler activation temperature on the suppression of conveyor belt fires. The sprinkler location and the activation temperature were found to have a major effect on the suppression of the belt fire, while the water flow rate had a minor effect. JF - Process Safety and Environmental Protection AU - Yuan, Liming AU - Smith, Alex C AD - Mine Safety and Health Research, National Institute for Occupational Safety and Health, P.O. Box 18070, Pittsburgh, PA 15236, USA, Lcy6@cdc.gov PY - 2015 SP - 93 EP - 101 PB - Institution of Chemical Engineers, Davis Bldg. Rugby Warwickshire CV21 3HQ United Kingdom VL - 95 SN - 0957-5820, 0957-5820 KW - Health & Safety Science Abstracts KW - Conveyor belt fires KW - Computational fluid dynamics KW - Water sprinkler systems KW - Flame spread KW - Ventilation KW - Fires KW - Mathematical models KW - Water flow KW - Sprays KW - Safety KW - Temperature KW - Simulation KW - Tunnels KW - Mines KW - Sprinkler systems KW - Safety engineering KW - Fluid dynamics KW - Air flow KW - H 7000:Fire Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1746887641?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Process+Safety+and+Environmental+Protection&rft.atitle=Numerical+modeling+of+water+spray+suppression+of+conveyor+belt+fires+in+a+large-scale+tunnel&rft.au=Yuan%2C+Liming%3BSmith%2C+Alex+C&rft.aulast=Yuan&rft.aufirst=Liming&rft.date=2015-05-01&rft.volume=95&rft.issue=&rft.spage=93&rft.isbn=&rft.btitle=&rft.title=Process+Safety+and+Environmental+Protection&rft.issn=09575820&rft_id=info:doi/10.1016%2Fj.psep.2015.02.018 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-12-01 N1 - Number of references - 23 N1 - Last updated - 2016-01-21 N1 - SubjectsTermNotLitGenreText - Fires; Mathematical models; Ventilation; Water flow; Safety; Sprays; Temperature; Simulation; Mines; Tunnels; Sprinkler systems; Safety engineering; Fluid dynamics; Air flow DO - http://dx.doi.org/10.1016/j.psep.2015.02.018 ER - TY - JOUR T1 - Surveillance for Dengue and Dengue-Associated Neurologic Syndromes in the United States AN - 1727686200; PQ0002118759 AB - Autochthonous dengue virus transmission has occurred in the continental United States with increased frequency during the last decade; the principal vector, Aedes aegypti, has expanded its geographic distribution in the southern United States. Dengue, a potentially fatal arboviral disease, is underreported, and US clinicians encountering patients with acute febrile illness consistent with dengue are likely to not be fully familiar with dengue diagnosis and management. Recently, investigators suggested that an outbreak of dengue likely occurred in Houston during 2003 based on retrospective laboratory testing of hospitalized cases with encephalitis and aseptic meningitis. Although certain aspects of the Houston testing results and argument for local transmission are doubtful, the report highlights the importance of prospective surveillance for dengue in Aedes-infested areas of the United States, the need for clinical training on dengue and its severe manifestations, and the need for laboratory testing in domestic patients presenting with febrile neurologic illness in these regions to include dengue. JF - American Journal of Tropical Medicine and Hygiene AU - Waterman, Stephen H AU - Margolis, Harold S AU - Sejvar, James J AD - United States-Mexico Unit, Division of Global Migration and Quarantine, US Centers for Disease Control and Prevention, San Diego, California, shw2@cdc.gov Y1 - 2015/05// PY - 2015 DA - May 2015 SP - 996 EP - 998 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 92 IS - 5 SN - 0002-9637, 0002-9637 KW - CSA Neurosciences Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Entomology Abstracts; Virology & AIDS Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Dengue virus KW - Aseptic meningitis KW - Symptoms KW - Aedes aegypti KW - Human diseases KW - Geographical distribution KW - Surveillance and enforcement KW - Vectors KW - Hosts KW - Encephalitis KW - Public health KW - Disease transmission KW - USA KW - Dengue KW - Hygiene KW - Aquatic insects KW - USA, Texas, Houston KW - K 03400:Human Diseases KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - J 02400:Human Diseases KW - Q1 08604:Stock assessment and management KW - N3 11027:Neurology & neuropathology KW - Q5 08524:Public health, medicines, dangerous organisms KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727686200?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Surveillance+for+Dengue+and+Dengue-Associated+Neurologic+Syndromes+in+the+United+States&rft.au=Waterman%2C+Stephen+H%3BMargolis%2C+Harold+S%3BSejvar%2C+James+J&rft.aulast=Waterman&rft.aufirst=Stephen&rft.date=2015-05-01&rft.volume=92&rft.issue=5&rft.spage=996&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0016 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Symptoms; Geographical distribution; Human diseases; Surveillance and enforcement; Hosts; Hygiene; Aquatic insects; Disease transmission; Public health; Aseptic meningitis; Dengue; Vectors; Encephalitis; Dengue virus; Aedes aegypti; USA; USA, Texas, Houston DO - http://dx.doi.org/10.4269/ajtmh.14-0016 ER - TY - JOUR T1 - Morbidity Associated with Schistosomiasis Before and After Treatment in Young Children in Rusinga Island, Western Kenya AN - 1727682074; PQ0002118751 AB - Schistosoma mansoni infection is a major cause of organomegaly and ultimately liver fibrosis in adults. Morbidity in pre-school-aged children is less defined, and they are currently not included in mass drug administration (MDA) programs for schistosomiasis control. We report results of a study of the association of schistosomiasis with organomegaly in a convenience sample of 201 children under 7 years old in Rusinga, Kenya on two cross-sectional visits, before and after praziquantel treatment. Data included stool examination and serology for schistosomiasis, the Niamey ultrasound protocol to stage hepatosplenic morbidity including organomegaly, and potential confounders including malaria. Unadjusted and adjusted Poisson regressions were performed. The baseline prevalence of schistosomiasis by antibody and/or stool was 80.3%. Schistomiasis was associated with hepatomegaly (adjusted prevalence ratio [aPR] = 1.4; 95% confidence interval [CI]: 1.0-2.1) and splenomegaly (aPR = 2.1; 95% CI: 1.2-3.7). The association with hepatomegaly persisted posttreatment (aPR = 1.4; 95% CI: 1.1-1.6). Schistosomiasis was associated with morbidity in this cohort. Efforts to include young children in mass treatment campaigns should intensify. JF - American Journal of Tropical Medicine and Hygiene AU - Davis, Stephanie M AU - Wiegand, Ryan E AU - Mulama, Fridah AU - Kareko, Edmund Ireri AU - Harris, Robert AU - Ochola, Elizabeth AU - Samuels, Aaron M AU - Rawago, Fredrick AU - Mwinzi, Pauline M AU - Fox, LeAnne M AU - Odiere, Maurice R AU - Won, Kimberly Y AD - Parasitic Diseases Branch, Division of Parasitic Diseases and Malaria, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, vic6@cdc.gov Y1 - 2015/05// PY - 2015 DA - May 2015 SP - 952 EP - 958 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 92 IS - 5 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Niger, Niamey KW - Schistosoma mansoni KW - Parasites KW - Human diseases KW - Fibrosis KW - Disease control KW - Malaria KW - Infection KW - Serology KW - Morbidity KW - Public health KW - Serological studies KW - Kenya KW - Islands KW - Praziquantel KW - Feces KW - Ultrasound KW - Drugs KW - Data processing KW - Schistosomiasis KW - Children KW - Antibodies KW - Ultrasonics KW - Liver KW - Splenomegaly KW - Hygiene KW - K 03400:Human Diseases KW - J 02400:Human Diseases KW - Q1 08485:Species interactions: pests and control KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727682074?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Morbidity+Associated+with+Schistosomiasis+Before+and+After+Treatment+in+Young+Children+in+Rusinga+Island%2C+Western+Kenya&rft.au=Davis%2C+Stephanie+M%3BWiegand%2C+Ryan+E%3BMulama%2C+Fridah%3BKareko%2C+Edmund+Ireri%3BHarris%2C+Robert%3BOchola%2C+Elizabeth%3BSamuels%2C+Aaron+M%3BRawago%2C+Fredrick%3BMwinzi%2C+Pauline+M%3BFox%2C+LeAnne+M%3BOdiere%2C+Maurice+R%3BWon%2C+Kimberly+Y&rft.aulast=Davis&rft.aufirst=Stephanie&rft.date=2015-05-01&rft.volume=92&rft.issue=5&rft.spage=952&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0346 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Parasites; Human diseases; Antibodies; Serological studies; Ultrasonics; Disease control; Schistosomiasis; Hygiene; Public health; Data processing; Fibrosis; Malaria; Children; Infection; Serology; Morbidity; Islands; Liver; Splenomegaly; Praziquantel; Feces; Drugs; Ultrasound; Schistosoma mansoni; Niger, Niamey; Kenya DO - http://dx.doi.org/10.4269/ajtmh.14-0346 ER - TY - JOUR T1 - Comparison of Antimicrobial Susceptibilities of Pharyngeal, Rectal, and Urethral Neisseria gonorrhoeae Isolates among Men Who Have Sex with Men AN - 1683352524; PQ0001539696 AB - U.S. surveillance for Neisseria gonorrhoeae antimicrobial susceptibilities is based exclusively on male urethral isolates. These data inform gonorrhea treatment guidelines, including recommendations for the treatment of extragenital infections, but data on the susceptibilities of extragenital isolates are limited. We compared the antimicrobial susceptibilities of pharyngeal, rectal, and urethral gonococcal isolates collected from men who have sex with men (MSM), at five sentinel sites throughout the United States. MICs were determined by the agar dilution method. Generalized linear models were used to compare (i) the proportions of isolates with elevated MICs and (ii) geometric mean MICs according to anatomic site, adjusted for city. In December 2011 to September 2013, totals of 205 pharyngeal, 261 rectal, and 976 urethral isolates were obtained. The proportions of isolates with elevated ceftriaxone MICs ( greater than or equal to 0.125 mu g/ml) did not differ according to anatomic site (0.5% of pharyngeal isolates, 1.5% of rectal isolates, and 1.7% of urethral isolates, with a city-adjusted odds ratio [aOR] of 0.4 [95% confidence interval {CI}, 0.0 to 3.9] for pharyngeal versus urethral isolates and an aOR of 0.9 [95% CI, 0.2 to 4.2] for rectal versus urethral isolates). The city-adjusted geometric mean ceftriaxone MICs of pharyngeal (0.0153 mu g/ml) and rectal (0.0157 mu g/ml) isolates did not differ from that of urethral isolates (0.0150 mu g/ml) (ratios of geometric mean MICs of 1.02 [95% CI, 0.90 to 1.17] and 1.05 [95% CI, 0.93 to 1.19], respectively). Similar results were observed for other antimicrobials, including cefixime and azithromycin. These findings suggest that, at the population level, gonococcal antimicrobial susceptibility surveillance based on urethral isolates from MSM adequately reflects the susceptibilities of N. gonorrhoeae strains circulating among MSM. JF - Antimicrobial Agents & Chemotherapy AU - Kidd, Sarah AU - Zaidi, Akbar AU - Asbel, Lenore AU - Baldwin, Tamara AU - Gratzer, Beau AU - Guerry, Sarah AU - Kerani, Roxanne P AU - Pathela, Preeti AU - Pettus, Kevin AU - Soge, Olusegun O AD - Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, skidd@cdc.gov. Y1 - 2015/05// PY - 2015 DA - May 2015 SP - 2588 EP - 2595 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 59 IS - 5 SN - 0066-4804, 0066-4804 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Agar KW - Data processing KW - Pharynx KW - Rectum KW - Ceftriaxone KW - Infection KW - Minimum inhibitory concentration KW - Neisseria gonorrhoeae KW - Models KW - Antimicrobial agents KW - Azithromycin KW - Cefixime KW - Gonorrhea KW - Population levels KW - Sex KW - A 01340:Antibiotics & Antimicrobials KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1683352524?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Comparison+of+Antimicrobial+Susceptibilities+of+Pharyngeal%2C+Rectal%2C+and+Urethral+Neisseria+gonorrhoeae+Isolates+among+Men+Who+Have+Sex+with+Men&rft.au=Kidd%2C+Sarah%3BZaidi%2C+Akbar%3BAsbel%2C+Lenore%3BBaldwin%2C+Tamara%3BGratzer%2C+Beau%3BGuerry%2C+Sarah%3BKerani%2C+Roxanne+P%3BPathela%2C+Preeti%3BPettus%2C+Kevin%3BSoge%2C+Olusegun+O&rft.aulast=Kidd&rft.aufirst=Sarah&rft.date=2015-05-01&rft.volume=59&rft.issue=5&rft.spage=2588&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.04476-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-05-01 N1 - Number of references - 38 N1 - Last updated - 2015-11-16 N1 - SubjectsTermNotLitGenreText - Agar; Rectum; Pharynx; Data processing; Ceftriaxone; Infection; Minimum inhibitory concentration; Antimicrobial agents; Models; Azithromycin; Cefixime; Population levels; Gonorrhea; Sex; Neisseria gonorrhoeae DO - http://dx.doi.org/10.1128/AAC.04476-14 ER - TY - JOUR T1 - Identification and Characterization of Multidrug-Resistant Salmonella enterica Serotype Albert Isolates in the United States AN - 1683351618; PQ0001539741 AB - Salmonella enterica is one of the most common causes of bacterial foodborne illness in the United States. Although most Salmonella infections are self-limiting, antimicrobial treatment of invasive salmonellosis is critical. The primary antimicrobial treatment options include fluoroquinolones or extended-spectrum cephalosporins, and resistance to these antimicrobial drugs may complicate treatment. At present, S. enterica is composed of more than 2,600 unique serotypes, which vary greatly in geographic prevalence, ecological niche, and the ability to cause human disease, and it is important to understand and mitigate the source of human infection, particularly when antimicrobial resistance is found. In this study, we identified and characterized 19 S. enterica serotype Albert isolates collected from food animals, retail meat, and humans in the United States during 2005 to 2013. All five isolates from nonhuman sources were obtained from turkeys or ground turkey, and epidemiologic data suggest poultry consumption or live-poultry exposure as the probable source of infection. S. enterica serotype Albert also appears to be geographically localized to the midwestern United States. All 19 isolates displayed multidrug resistance, including decreased susceptibility to fluoroquinolones and resistance to extended-spectrum cephalosporins. Turkeys are a likely source of multidrug-resistant S. enterica serotype Albert, and circulation of resistance plasmids, as opposed to the expansion of a single resistant strain, is playing a role. More work is needed to understand why these resistance plasmids spread and how their presence and the serotype they reside in contribute to human disease. JF - Antimicrobial Agents & Chemotherapy AU - Folster, Jason P AU - Campbell, Davina AU - Grass, Julian AU - Brown, Allison C AU - Bicknese, Amelia AU - Tolar, Beth AU - Joseph, Lavin A AU - Plumblee, Jodie R AU - Walker, Carrie AU - Fedorka-Cray, Paula J AD - Division of Foodborne, Waterborne and Environmental Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, gux8@cdc.gov. Y1 - 2015/05// PY - 2015 DA - May 2015 SP - 2774 EP - 2779 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 59 IS - 5 SN - 0066-4804, 0066-4804 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Cephalosporins KW - Poultry KW - Data processing KW - Serotypes KW - Fluoroquinolones KW - Niches KW - Drug resistance KW - Food KW - Plasmids KW - Infection KW - Antimicrobial agents KW - Meat KW - Salmonella enterica KW - Salmonellosis KW - Multidrug resistance KW - A 01330:Food Microbiology KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1683351618?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Identification+and+Characterization+of+Multidrug-Resistant+Salmonella+enterica+Serotype+Albert+Isolates+in+the+United+States&rft.au=Folster%2C+Jason+P%3BCampbell%2C+Davina%3BGrass%2C+Julian%3BBrown%2C+Allison+C%3BBicknese%2C+Amelia%3BTolar%2C+Beth%3BJoseph%2C+Lavin+A%3BPlumblee%2C+Jodie+R%3BWalker%2C+Carrie%3BFedorka-Cray%2C+Paula+J&rft.aulast=Folster&rft.aufirst=Jason&rft.date=2015-05-01&rft.volume=59&rft.issue=5&rft.spage=2774&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.05183-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-05-01 N1 - Number of references - 30 N1 - Last updated - 2015-11-16 N1 - SubjectsTermNotLitGenreText - Cephalosporins; Poultry; Serotypes; Data processing; Fluoroquinolones; Food; Drug resistance; Niches; Infection; Plasmids; Antimicrobial agents; Meat; Salmonellosis; Multidrug resistance; Salmonella enterica DO - http://dx.doi.org/10.1128/AAC.05183-14 ER - TY - JOUR T1 - An LC-MS/MS method for serum methylmalonic acid suitable for monitoring vitamin B12 status in population surveys AN - 1746891040; PQ0001432169 AB - Methylmalonic acid (MMA), a functional indicator of vitamin B sub(12) insufficiency, was measured in the US population in the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2004 using a GC/MS procedure that required 275 mu L of sample and had a low throughput (36 samples/run). Our objective was to introduce a more efficient yet highly accurate LC-MS/MS method for NHANES 2011-2014. We adapted the sample preparation with some modifications from a published isotope-dilution LC-MS/MS procedure. The procedure utilized liquid-liquid extraction and generation of MMA dibutyl ester. Reversed-phase chromatography with isocratic elution allowed baseline resolution of MMA from its naturally occurring structural isomer succinic acid within 4.5 min. Our new method afforded an increased throughput ( less than or equal to 160 samples/run) and measured serum MMA with high sensitivity (LOD=22.1 nmol/L) in only 75 mu L of sample. Mean ( plus or minus SD) recovery of MMA spiked into serum (2 d, 4 levels, 2 replicates each) was 94 % plus or minus 5.5 %. Total imprecision (41 d, 2 replicates each) for three serum quality control pools was 4.9 %-7.9 % (97.1-548 nmol/L). The LC-MS/MS method showed excellent correlation (n=326, r=0.99) and no bias (Deming regression, Bland-Altman analysis) compared to the previous GC/MS method. Both methods produced virtually identical mean ( plus or minus SD) MMA concentrations [LC-MS/MS: 18.47 plus or minus 0.71 ng/mL (n=17), GC/MS: 18.18 plus or minus 0.67 ng/mL (n=11)] on a future plasma reference material compared with a GC/MS method procedure from the National Institute of Standards and Technology [18.41 plus or minus 0.70 ng/mL (n=15)]. No adjustment will be necessary to compare previous (1999-2004) to future (2011-2014) NHANES MMA data. [Figure not available: see fulltext.] JF - Analytical and Bioanalytical Chemistry AU - Mineva, Ekaterina M AU - Zhang, Mindy AU - Rabinowitz, Daniel J AU - Phinney, Karen W AU - Pfeiffer, Christine M AD - Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, 30341, USA, cfp8@cdc.gov PY - 2015 SP - 2955 EP - 2964 PB - Springer Science+Business Media, Berlin/Heidelberg Germany VL - 407 IS - 11 SN - 1618-2642, 1618-2642 KW - Aqualine Abstracts; Water Resources Abstracts KW - Chromatography KW - Surveys KW - Esters KW - Sample Preparation KW - Analytical Methods KW - Acids KW - Vitamins KW - Standards KW - Monitoring KW - AQ 00001:Water Resources and Supplies KW - SW 0810:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1746891040?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytical+and+Bioanalytical+Chemistry&rft.atitle=An+LC-MS%2FMS+method+for+serum+methylmalonic+acid+suitable+for+monitoring+vitamin+B12+status+in+population+surveys&rft.au=Mineva%2C+Ekaterina+M%3BZhang%2C+Mindy%3BRabinowitz%2C+Daniel+J%3BPhinney%2C+Karen+W%3BPfeiffer%2C+Christine+M&rft.aulast=Mineva&rft.aufirst=Ekaterina&rft.date=2015-04-01&rft.volume=407&rft.issue=11&rft.spage=2955&rft.isbn=&rft.btitle=&rft.title=Analytical+and+Bioanalytical+Chemistry&rft.issn=16182642&rft_id=info:doi/10.1007%2Fs00216-014-8148-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-12-01 N1 - Number of references - 29 N1 - Last updated - 2016-01-21 N1 - SubjectsTermNotLitGenreText - Sample Preparation; Chromatography; Analytical Methods; Vitamins; Acids; Surveys; Standards; Monitoring; Esters DO - http://dx.doi.org/10.1007/s00216-014-8148-2 ER - TY - JOUR T1 - Home Visits to Assess the Reliability of Caregiver-Reported Use of Insecticide-Treated Bednets by Children in Machinga District, Malawi AN - 1727682977; PQ0002118729 AB - A malaria cohort study was conducted among young children in Machinga District, Malawi, following distribution of insecticide-treated bednets (ITNs) in May 2012. To assess ITN use, two independently sampled subsets of children (211 during survey 1 [December 2012-January 2013] and 325 during survey 2 [September-October 2013]) were randomly selected to compare the proportions of positive and negative agreement between caregiver verbal reports at monthly interviews with visual observation of the ITN at home visits. Caregiver-reported ITN use was consistently high during both surveys (98.1% and 96.0%, respectively; P = 0.17). Home visit-based ITN use fell significantly (P < 0.001) from survey 1 (98.6%) to survey 2 (88.6%). The proportions of positive agreement between caregiver report and home visit in the first and second surveys were 98.8% (95% confidence interval [CI] 97.6-99.8%) and 93.3% (95% CI 91.2-95.3%), respectively. The proportions of negative agreement in the first and second surveys were 28.6% (95% CI 0-75.0%) and 20.0% (95% CI 0.1-35.0%), respectively. ITN use by children was high in Machinga District, and caregiver reports and home visits with visual confirmation of the net demonstrated a high level of agreement for use of ITNs, but a low level of agreement when ITNs were not used. JF - American Journal of Tropical Medicine and Hygiene AU - Wong, Jacklyn AU - Shah, Monica P AU - Mwandama, Dyson AU - Gimnig, John E AU - Lindblade, Kim A AU - Mathanga, Don P AD - Entomology Branch, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia, mshah2@cdc.gov Y1 - 2015/04// PY - 2015 DA - April 2015 SP - 825 EP - 827 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 92 IS - 4 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Human diseases KW - Malaria KW - Malawi KW - Children KW - Hygiene KW - K 03400:Human Diseases KW - J 02400:Human Diseases KW - Q1 08604:Stock assessment and management KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727682977?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Home+Visits+to+Assess+the+Reliability+of+Caregiver-Reported+Use+of+Insecticide-Treated+Bednets+by+Children+in+Machinga+District%2C+Malawi&rft.au=Wong%2C+Jacklyn%3BShah%2C+Monica+P%3BMwandama%2C+Dyson%3BGimnig%2C+John+E%3BLindblade%2C+Kim+A%3BMathanga%2C+Don+P&rft.aulast=Wong&rft.aufirst=Jacklyn&rft.date=2015-04-01&rft.volume=92&rft.issue=4&rft.spage=825&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0768 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Human diseases; Malaria; Hygiene; Children; Malawi DO - http://dx.doi.org/10.4269/ajtmh.14-0768 ER - TY - JOUR T1 - Unstable Sitting in the Workplace-Are There Physical Activity Benefits? AN - 1694968386; PQ0001516877 AB - The increasingly popular practice of using a stability ball (exercise/fitness ball) as a sitting surface runs counter to conventional human factors/'ergonomics guidelines for seated workspace design. Employees sitting on stability balls in an office environment present safely risks that might be justifiable if the practice has a definitive benefit to the promotion of health. However, the published studies and best evidence to date call into question even, the theoretical basis for this practice and. do not suggest, significant health benefits. First, biomechanical studies do not confirm the intended trunk muscle activation. Second, energy expenditure studies show a small (if any) increase in metabolic demand that is unlikely to be effective in combating sedentary work risk factors. Until studies demonstrate more conclusive benefits, the practice of stability ball sitting should, be vieioed skeptically as a general, workplace recommendation in the interest of health or wellness. JF - American Journal of Health Promotion AU - Lowe, Brian D AU - Swanson, Naomi G AU - Hudock, Stephen D AU - Lotz, W Gregory AD - Division of Applied Research and Technolog, National Institute for Occupational Safety and Health, 1090 Tusculum Ave., MS C-24, Cincinnati, OH 45226, blowe@cdc.gov PY - 2015 SP - 207 EP - 209 PB - American Journal of Health Promotion, 1660 Cass Lake Road, Suite 104 Keego Harbor MI 48320 United States VL - 29 IS - 4 SN - 0890-1171, 0890-1171 KW - Risk Abstracts; Health & Safety Science Abstracts; Physical Education Index KW - Physical activity KW - Promotion KW - Running KW - Guidelines KW - Muscles KW - Health KW - Exercise KW - Practice KW - Working conditions KW - Risk factors KW - Energy KW - Wellness KW - Human factors KW - Sitting KW - Balance KW - Biomechanics KW - Ergonomics KW - Health promotion KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1694968386?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Health+Promotion&rft.atitle=Unstable+Sitting+in+the+Workplace-Are+There+Physical+Activity+Benefits%3F&rft.au=Lowe%2C+Brian+D%3BSwanson%2C+Naomi+G%3BHudock%2C+Stephen+D%3BLotz%2C+W+Gregory&rft.aulast=Lowe&rft.aufirst=Brian&rft.date=2015-04-01&rft.volume=29&rft.issue=4&rft.spage=207&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Health+Promotion&rft.issn=08901171&rft_id=info:doi/10.4278%2Fajhp.140331-CIT-127 LA - English DB - Physical Education Index; ProQuest Environmental Science Collection N1 - Date revised - 2015-07-01 N1 - Last updated - 2015-12-09 N1 - SubjectsTermNotLitGenreText - Running; Promotion; Wellness; Health; Exercise; Sitting; Practice; Balance; Ergonomics; Energy; Physical activity; Risk factors; Guidelines; Muscles; Human factors; Working conditions; Biomechanics; Health promotion DO - http://dx.doi.org/10.4278/ajhp.140331-CIT-127 ER - TY - JOUR T1 - Reinfection after successful eradication of Helicobacter pylori in three different populations in Alaska AN - 1673383810; PQ0001282392 AB - We performed a study to determine rates of reinfection in three groups followed for 2 years after successful treatment: American Indian/Alaska Native (AI/AN) persons living in urban (group 1) and rural (group 2) communities, and urban Alaska non-Native persons (group 3). We enrolled adults diagnosed with H. pylori infection based on a positive urea breath test ( super(13)C-UBT). After successful treatment was documented at 2 months, we tested each patient by super(13)C-UBT at 4, 6, 12 and 24 months. At each visit, participants were asked about medication use, illnesses and risk factors for reinfection. We followed 229 persons for 2 years or until they became reinfected. H. pylori reinfection occurred in 36 persons; cumulative reinfection rates were 14.5%, 22.1%, and 12.0% for groups 1, 2, and 3, respectively. Study participants who became reinfected were more likely to have peptic ulcer disease (P = 0.02), low education level (P = 0.04), or have a higher proportion of household members infected with H. pylori compared to participants who did not become reinfected (P = 0.03). Among all three groups, reinfection occurred at rates higher than those reported for other US populations (<5% at 2 years); rural AI/AN individuals appear to be at highest risk for reinfection. JF - Epidemiology and Infection AU - Bruce, M G AU - BRUDEN, D L AU - Morris, J M AU - REASONOVER, AL AU - Sacco, F AU - Hurlburt, D AU - Hennessy, T W AU - Gove, J AU - Parkinson, A AU - SAHAGUN, G AU - Davis, P AU - KLEJKA, J AU - McMAHON, B J AD - Arctic Investigations Program, Division of Preparedness and Emerging Infections, National Center for Emerging Zoonotic and Infectious Diseases, Centers for Disease Control and Prevention (CDC), Anchorage, Alaska, USA, zwa8@cdc.gov Y1 - 2015/04// PY - 2015 DA - April 2015 SP - 1236 EP - 1246 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 143 IS - 6 SN - 0950-2688, 0950-2688 KW - Microbiology Abstracts B: Bacteriology; Risk Abstracts KW - Helicobacter pylori KW - INE, USA, Alaska KW - Urea KW - Infection KW - Education KW - Households KW - Risk factors KW - peptic ulcers KW - Drugs KW - Ethnic groups KW - Rural areas KW - J 02400:Human Diseases KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1673383810?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Reinfection+after+successful+eradication+of+Helicobacter+pylori+in+three+different+populations+in+Alaska&rft.au=Bruce%2C+M+G%3BBRUDEN%2C+D+L%3BMorris%2C+J+M%3BREASONOVER%2C+AL%3BSacco%2C+F%3BHurlburt%2C+D%3BHennessy%2C+T+W%3BGove%2C+J%3BParkinson%2C+A%3BSAHAGUN%2C+G%3BDavis%2C+P%3BKLEJKA%2C+J%3BMcMAHON%2C+B+J&rft.aulast=Bruce&rft.aufirst=M&rft.date=2015-04-01&rft.volume=143&rft.issue=6&rft.spage=1236&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268814001770 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-04-01 N1 - Number of references - 38 N1 - Last updated - 2016-03-30 N1 - SubjectsTermNotLitGenreText - Risk factors; Urea; peptic ulcers; Infection; Education; Households; Drugs; Ethnic groups; Rural areas; Helicobacter pylori; INE, USA, Alaska DO - http://dx.doi.org/10.1017/S0950268814001770 ER - TY - JOUR T1 - Preventing unintentional injuries in the home using the Health Impact Pyramid. AN - 1669448128; 25829110 AB - Injuries continue to be the leading cause of death for the first four decades of life. These injuries result from a confluence of behavioral, physical, structural, environmental, and social factors. Taken together, these illustrate the importance of taking a broad and multileveled approach to injury prevention. Using examples from fall, fire, scald, and poisoning-related injuries, this article illustrates the utility of an approach that incorporates a social-environmental perspective in identifying and selecting interventions to improve the health and safety of individuals. Injury prevention efforts to prevent home injuries benefit from multilevel modifications of behavior, public policy, laws and enforcement, the environment, consumer products and engineering standards, as demonstrated with Frieden's Health Impact Pyramid. A greater understanding, however, is needed to explain the associations between tiers. While interventions that include modifications of the social environment are being field-tested, much more work needs to be done in measuring social-environmental change and in evaluating these programs to disentangle what works best. © 2015 Society for Public Health Education. JF - Health education & behavior : the official publication of the Society for Public Health Education AU - Mack, Karin A AU - Liller, Karen D AU - Baldwin, Grant AU - Sleet, David AD - Centers for Disease Control and Prevention, Atlanta, GA, USA kmack@cdc.gov. ; University of South Florida, Tampa, FL, USA. ; Centers for Disease Control and Prevention, Atlanta, GA, USA. Y1 - 2015/04// PY - 2015 DA - April 2015 SP - 115S EP - 122S VL - 42 IS - 1 Suppl KW - Index Medicus KW - Health Impact Pyramid KW - poisonings KW - falls KW - injury prevention KW - fire KW - Socioeconomic Factors KW - Age Factors KW - Building Codes KW - Sex Factors KW - Social Change KW - Risk Factors KW - Humans KW - Poisoning -- prevention & control KW - Fires -- prevention & control KW - Social Environment KW - Burns -- prevention & control KW - Accidents, Home -- prevention & control KW - Safety KW - Wounds and Injuries -- prevention & control KW - Health Education -- organization & administration UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1669448128?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+education+%26+behavior+%3A+the+official+publication+of+the+Society+for+Public+Health+Education&rft.atitle=Preventing+unintentional+injuries+in+the+home+using+the+Health+Impact+Pyramid.&rft.au=Mack%2C+Karin+A%3BLiller%2C+Karen+D%3BBaldwin%2C+Grant%3BSleet%2C+David&rft.aulast=Mack&rft.aufirst=Karin&rft.date=2015-04-01&rft.volume=42&rft.issue=1+Suppl&rft.spage=115S&rft.isbn=&rft.btitle=&rft.title=Health+education+%26+behavior+%3A+the+official+publication+of+the+Society+for+Public+Health+Education&rft.issn=1552-6127&rft_id=info:doi/10.1177%2F1090198114568306 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2016-01-13 N1 - Date created - 2015-04-01 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Cited By: J Burn Care Res. 2006 May-Jun;27(3):314-22; discussion 323-4 [16679899] Am J Health Behav. 2006 May-Jun;30(3):259-67 [16712440] Age Ageing. 2006 Sep;35 Suppl 2:ii55-ii59 [16926207] Pediatrics. 2009 Aug;124(2):541-7 [19596735] Am J Prev Med. 2009 Sep;37(3):181-7 [19666156] Am J Public Health. 2010 Apr;100(4):590-5 [20167880] Am J Public Health. 2010 Oct;100(10):1824-5 [20724668] Cochrane Database Syst Rev. 2011;(2):CD003600 [21328262] Arch Pediatr Adolesc Med. 2011 Apr;165(4):339-45 [21464382] J Urban Health. 2011 Jun;88(3):582-97 [21365355] Public Health Rep. 2012 Mar-Apr;127(2):147-55 [22379214] Cochrane Database Syst Rev. 2012;9:CD007146 [22972103] Pediatrics. 2012 Dec;130(6):1053-9 [23147973] J Inj Violence Res. 2013 Jan;5(1):61-9 [22868399] Am J Prev Med. 2013 Mar;44(3):239-46 [23415120] MMWR Morb Mortal Wkly Rep. 2013 Jul 5;62(26):537-42 [23820967] N Engl J Med. 2001 Jun 21;344(25):1911-6 [11419429] Public Health Rep. 2007 Mar-Apr;122(2):224-31 [17357365] Inj Prev. 2007 Apr;13(2):137-40 [17446257] Int J Inj Contr Saf Promot. 2007 Jun;14(2):109-17 [17510847] Accid Anal Prev. 2008 Jan;40(1):61-8 [18215533] Pediatrics. 2008 May;121(5):930-7 [18450896] Am J Prev Med. 2008 Oct;35(4):370-379 [18779031] Inj Prev. 2009 Jun;15(3):197-204 [19494100] Clin Toxicol (Phila). 2013 Dec;51(10):949-1229 [24359283] Health Educ Behav. 2013 Oct;40(5):520-5 [24048612] Am J Public Health. 1977 Dec;67(12):1143-7 [596496] Pediatrics. 1979 May;63(5):687-93 [440889] Pediatrics. 1982 Mar;69(3):363-70 [7063294] J Pediatr Surg. 1983 Aug;18(4):509-11 [6620098] Health Educ Q. 1988 Winter;15(4):351-77 [3068205] Pediatrics. 1991 Sep;88(3):572-7 [1881739] JAMA. 1996 Jun 5;275(21):1661-5 [8637140] Age Ageing. 1997 May;26(3):195-202 [9223715] Inj Prev. 1999 Jun;5(2):145-50 [10385837] Inj Prev. 1999 Sep;5(3):217-25 [10518271] Am J Prev Med. 2005 Jan;28(1):73-9 [15626560] Am J Prev Med. 2005 Jan;28(1):80-7 [15626561] Am J Prev Med. 2005 Jan;28(1):88-94 [15626562] Arch Pediatr Adolesc Med. 2005 Jun;159(6):557-60 [15939855] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1177/1090198114568306 ER - TY - JOUR T1 - Reduced West Nile Virus Transmission Around Communal Roosts of Great-Tailed Grackle (Quiscalus mexicanus) AN - 1680440303; PQ0001534672 AB - West Nile virus has caused several outbreaks among humans in the Phoenix metropolitan area (Arizona, southwest USA) within the last decade. Recent ecologic studies have implicated Culex quinquefasciatus and Culex tarsalis as the mosquito vectors and identified three abundant passerine birds-great-tailed grackle (Quiscalus mexicanus), house sparrow (Passer domesticus), and house finch (Haemorhous mexicanus)-as key amplifiers among vertebrates. Nocturnal congregations of certain species have been suggested as critical for late summer West Nile virus amplification. We evaluated the hypothesis that house sparrow (P. domesticus) and/or great-tailed grackle (Q. mexicanus) communal roost sites (n = 22 and n = 5, respectively) in a primarily suburban environment were spatially associated with West Nile virus transmission indices during the 2010 outbreak of human neurological disease in metropolitan Phoenix. Spatial associations between human case residences and communal roosts were non-significant for house sparrows, and were negative for great-tailed grackle. Several theories that explain these observations are discussed, including the possibility that grackle communal roosts are protective. JF - EcoHealth AU - Komar, Nicholas AU - Colborn, James M AU - Horiuchi, Kalanthe AU - Delorey, Mark AU - Biggerstaff, Brad AU - Damian, Dan AU - Smith, Kirk AU - Townsend, John AD - Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, 3156 Rampart Road, Fort Collins, CO, 80521, USA, nck6@cdc.gov Y1 - 2015/03// PY - 2015 DA - Mar 2015 SP - 144 EP - 151 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 12 IS - 1 SN - 1612-9202, 1612-9202 KW - Ecology Abstracts; Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Culex quinquefasciatus KW - Neurological diseases KW - Suburban environments KW - Housing KW - Vectors KW - Summer KW - Disease transmission KW - Passer domesticus KW - Residential areas KW - USA, Arizona KW - Culex tarsalis KW - Outbreaks KW - Quiscalus mexicanus KW - West Nile virus KW - Metropolitan areas KW - USA, Arizona, Phoenix KW - Roosts KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - D 04040:Ecosystem and Ecology Studies KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1680440303?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=EcoHealth&rft.atitle=Reduced+West+Nile+Virus+Transmission+Around+Communal+Roosts+of+Great-Tailed+Grackle+%28Quiscalus+mexicanus%29&rft.au=Komar%2C+Nicholas%3BColborn%2C+James+M%3BHoriuchi%2C+Kalanthe%3BDelorey%2C+Mark%3BBiggerstaff%2C+Brad%3BDamian%2C+Dan%3BSmith%2C+Kirk%3BTownsend%2C+John&rft.aulast=Komar&rft.aufirst=Nicholas&rft.date=2015-03-01&rft.volume=12&rft.issue=1&rft.spage=144&rft.isbn=&rft.btitle=&rft.title=EcoHealth&rft.issn=16129202&rft_id=info:doi/10.1007%2Fs10393-014-0993-0 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-05-01 N1 - Number of references - 36 N1 - Last updated - 2015-10-15 N1 - SubjectsTermNotLitGenreText - Suburban environments; Neurological diseases; Vectors; Disease transmission; Roosts; Housing; Residential areas; Summer; Outbreaks; Metropolitan areas; Passer domesticus; Culex quinquefasciatus; Culex tarsalis; West Nile virus; Quiscalus mexicanus; USA, Arizona; USA, Arizona, Phoenix DO - http://dx.doi.org/10.1007/s10393-014-0993-0 ER - TY - JOUR T1 - A PUBLIC HEALTH PERSPECTIVE ON THE U.S. RESPONSE TO THE FUKUSHIMA RADIOLOGICAL EMERGENCY AN - 1673381723; PQ0001285354 AB - On 11 March 2011, northern Japan was struck by first a magnitude 9.0 earthquake off the eastern coast and then by an ensuing tsunami. At the Fukushima Dai-ichi Nuclear Power Plant (NPP), these twin disasters initiated a cascade of events that led to radionuclide releases. Radioactive material from Japan was subsequently transported to locations around the globe, including the U.S. Events during the response illustrated some U.S. preparedness challenges that previously had been anticipated and others that were newly identified. Some of these challenges include the following: (1) Capacity, including radiation health experts, for monitoring potentially exposed people for radioactive contamination are limited and may not be adequate at the time of a large-scale radiological incident; (2) there is no public health authority to detain people contaminated with radioactive materials; etc. Members of the public health community can draw on this experience to improve public health preparedness. JF - Health Physics AU - Whitcomb, Robert C, Jr AU - Ansari, Armin J AU - Buzzell, Jennifer J AU - McCurley, M Carol AU - Miller, Charles W AU - Smith, James M AU - Evans, D Lynn AD - Radiation Studies Branch, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, Mailstop F58, Atlanta, GA 30341, byw3@cdc.gov Y1 - 2015/03// PY - 2015 DA - Mar 2015 SP - 357 EP - 363 PB - Williams & Wilkins, 351 W. Camden St. Baltimore MD 21201 United States VL - 108 IS - 3 SN - 0017-9078, 0017-9078 KW - Pollution Abstracts; Health & Safety Science Abstracts KW - dose assessment KW - emergency planning KW - public information KW - radiation KW - Earthquakes KW - Nuclear power plants KW - Coastal zone KW - Radiation KW - Radioactive materials KW - Seismic activity KW - Disasters KW - Radioisotopes KW - Radioactive pollution KW - Tsunamis KW - Public health KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - P 1000:MARINE POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1673381723?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+Physics&rft.atitle=A+PUBLIC+HEALTH+PERSPECTIVE+ON+THE+U.S.+RESPONSE+TO+THE+FUKUSHIMA+RADIOLOGICAL+EMERGENCY&rft.au=Whitcomb%2C+Robert+C%2C+Jr%3BAnsari%2C+Armin+J%3BBuzzell%2C+Jennifer+J%3BMcCurley%2C+M+Carol%3BMiller%2C+Charles+W%3BSmith%2C+James+M%3BEvans%2C+D+Lynn&rft.aulast=Whitcomb&rft.aufirst=Robert&rft.date=2015-03-01&rft.volume=108&rft.issue=3&rft.spage=357&rft.isbn=&rft.btitle=&rft.title=Health+Physics&rft.issn=00179078&rft_id=info:doi/10.1097%2FHP.0000000000000198 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-04-01 N1 - Last updated - 2015-05-27 N1 - SubjectsTermNotLitGenreText - Earthquakes; Nuclear power plants; Coastal zone; Radiation; Radioactive materials; Radioisotopes; Disasters; Seismic activity; Radioactive pollution; Tsunamis; Public health DO - http://dx.doi.org/10.1097/HP.0000000000000198 ER - TY - JOUR T1 - Blood cadmium and depressive symptoms in young adults (aged 20-39 years) AN - 1664200090; PQ0001226916 AB - Genetic and environmental factors contribute to the risk of depression and several studies have noted an association between tobacco smoke and depression. Cadmium is a neurotoxicant and the main source of non-occupational exposure is tobacco smoke. We conducted a cross-sectional analysis of data from 2892 young adult (aged 20-39 years) participants of the National Health and Nutrition Examination Survey (NHANES) 2007-2010. Multivariate logistic regressions, adjusted for age, sex, race/ethnicity, education, poverty income ratio (PIR), obesity, alcohol intake, blood lead (BPb) and smoking status, were used to analyze the association between blood cadmium (BCd) and depressive symptoms, as determined by the score on the nine-item Patient Health Questionnaire (PHQ-9). Individuals in the highest BCd quartile had higher odds of having depressive symptoms [odds ratio (OR) 2.79, 95% confidence interval (CI) 1.84-4.25] than those in the lowest BCd quartile. Smoking status, but not BPb, was statistically significantly associated with depressive symptoms. Stratification by smoking status found that BCd was significantly associated with depressive symptoms in both non-smokers (OR 2.91, 95% CI 1.12-7.58) and current smokers (OR 2.69, 95% CI 1.13-6.42). This is the first study to report an association between BCd levels and depressive symptoms using a nationally representative sample. The association of cadmium with depressive symptoms was independent of smoking status. If this association is further confirmed, the continued efforts at reducing cadmium exposures, mainly through tobacco smoking cessation programs, may decrease the incidence of depression. JF - Psychological Medicine AU - Scinicariello, F AU - Buser, M C AD - Division of Toxicology and Human Health Sciences, Agency for Toxic Substances and Disease Registry (ATSDR), Atlanta, Georgia, USA, fes6@cdc.gov Y1 - 2015/03// PY - 2015 DA - Mar 2015 SP - 807 EP - 815 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 45 IS - 4 SN - 0033-2917, 0033-2917 KW - Health & Safety Science Abstracts; Risk Abstracts; CSA Neurosciences Abstracts KW - Stratification KW - Nutrition KW - Environmental factors KW - Income KW - Smoking KW - Tobacco KW - Cadmium KW - Ethnic groups KW - Alcohol KW - Obesity KW - Tobacco smoking KW - Inventories KW - Depression KW - Data processing KW - Alcoholic beverages KW - Blood levels KW - Smoke KW - Blood KW - Education KW - Neurotoxicity KW - Young adults KW - N3 11001:Behavioral and Cognitive Neuroscience KW - H 12000:Epidemiology and Public Health KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1664200090?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Psychological+Medicine&rft.atitle=Blood+cadmium+and+depressive+symptoms+in+young+adults+%28aged+20-39+years%29&rft.au=Scinicariello%2C+F%3BBuser%2C+M+C&rft.aulast=Scinicariello&rft.aufirst=F&rft.date=2015-03-01&rft.volume=45&rft.issue=4&rft.spage=807&rft.isbn=&rft.btitle=&rft.title=Psychological+Medicine&rft.issn=00332917&rft_id=info:doi/10.1017%2FS0033291714001883 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Number of references - 41 N1 - Last updated - 2015-09-03 N1 - SubjectsTermNotLitGenreText - Smoke; Inventories; Tobacco smoking; Obesity; Blood; Alcoholic beverages; Data processing; Depression; Cadmium; Environmental factors; Nutrition; Ethnic groups; Alcohol; Stratification; Income; Blood levels; Smoking; Education; Neurotoxicity; Tobacco; Young adults DO - http://dx.doi.org/10.1017/S0033291714001883 ER - TY - JOUR T1 - Factors Associated with Symptoms of Depression Among Bhutanese Refugees in the United States AN - 1746892739; PQ0002271893 AB - Refugees are at risk for psychiatric morbidity, yet little is known about their mental health conditions. We identified factors associated with depression symptoms among Bhutanese refugees in the US. We randomly selected adult Bhutanese refugees (N = 386) to complete a cross-sectional survey concerning demographics, mental health symptoms, and associated risk factors. The case definition for depression symptoms was greater than or equal to 1.75 mean depression score on the Hopkins Symptom Checklist-25. More women (26 %) than men (16 %) reported depression symptoms (p = 0.0097). Higher odds of depression symptoms were associated with being a family provider, self-reported poor health, and inability to read and write Nepali (OR 4.6, 39.7 and 4.3, respectively) among men; and self-reported poor health and inability to read and write Nepali (OR 7.6, and 2.6 respectively) among women. US-settled Bhutanese refugees are at risk for depression. Providers should be aware of these concerns. Culturally appropriate mental health services should be made more accessible at a local level. JF - Journal of Immigrant and Minority Health AU - Vonnahme, Laura A AU - Lankau, Emily W AU - Ao, Trong AU - Shetty, Sharmila AU - Cardozo, Barbara Lopes AD - Division of Global Migration and Quarantine, US Centers for Disease Control and Prevention, Atlanta, GA, USA, kdy1@cdc.gov PY - 2015 SP - 1705 EP - 1714 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 17 IS - 6 SN - 1557-1912, 1557-1912 KW - Risk Abstracts KW - Demography KW - USA KW - Mental disorders KW - Depression KW - Risk factors KW - Immigrants KW - Refugees KW - Morbidity KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1746892739?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Immigrant+and+Minority+Health&rft.atitle=Factors+Associated+with+Symptoms+of+Depression+Among+Bhutanese+Refugees+in+the+United+States&rft.au=Vonnahme%2C+Laura+A%3BLankau%2C+Emily+W%3BAo%2C+Trong%3BShetty%2C+Sharmila%3BCardozo%2C+Barbara+Lopes&rft.aulast=Vonnahme&rft.aufirst=Laura&rft.date=2015-02-01&rft.volume=17&rft.issue=6&rft.spage=1705&rft.isbn=&rft.btitle=&rft.title=Journal+of+Immigrant+and+Minority+Health&rft.issn=15571912&rft_id=info:doi/10.1007%2Fs10903-014-0120-x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-12-01 N1 - Number of references - 33 N1 - Last updated - 2015-12-23 N1 - SubjectsTermNotLitGenreText - Demography; Mental disorders; Depression; Risk factors; Immigrants; Refugees; Morbidity; USA DO - http://dx.doi.org/10.1007/s10903-014-0120-x ER - TY - JOUR T1 - Migration Patterns and Characteristics of Sexual Partners Associated with Unprotected Sexual Intercourse Among Hispanic Immigrant and Migrant Women in the United States AN - 1746892144; PQ0002271899 AB - In 2011, Hispanic immigrant women comprised 44 % of HIV diagnoses among Hispanic women in the United States but little is known about factors that may place these women at risk for infection with HIV or sexually transmitted diseases. From March 2005 to February 2007, women were recruited at community-based organizations offering services to immigrant and migrant communities in five U.S. states. We report factors independently associated with unprotected anal and vaginal sex in the past 12 months among Hispanic immigrant and migrant women. Greater work-related mobility was associated with unprotected anal sex, while recency of immigration and prior refusal of HIV testing were associated with women's reports of unprotected vaginal sex. Prior sex with an injection drug user was associated with reports of both unprotected anal and vaginal sex. Findings highlight the need for HIV/STD risk reduction interventions designed specifically for Hispanic immigrant and migrant women. JF - Journal of Immigrant and Minority Health AU - Valverde, Eduardo E AU - Painter, Thomas AU - Heffelfinger, James D AU - Schulden, Jeffrey D AU - Chavez, Pollyanna AU - DiNenno, Elizabeth A AD - Department of Health and Human Services, Centers for Disease Control and Prevention, Atlanta, GA, USA, Evalverde@cdc.gov PY - 2015 SP - 1826 EP - 1833 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 17 IS - 6 SN - 1557-1912, 1557-1912 KW - Risk Abstracts KW - Mobility KW - Immigrants KW - Intervention KW - Risk reduction KW - Anal sex KW - Drug abuse KW - Infection KW - Sexual behavior KW - USA KW - Human immunodeficiency virus KW - Risk factors KW - Females KW - Sexually transmitted diseases KW - Migrants KW - Ethnic groups KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1746892144?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Immigrant+and+Minority+Health&rft.atitle=Migration+Patterns+and+Characteristics+of+Sexual+Partners+Associated+with+Unprotected+Sexual+Intercourse+Among+Hispanic+Immigrant+and+Migrant+Women+in+the+United+States&rft.au=Valverde%2C+Eduardo+E%3BPainter%2C+Thomas%3BHeffelfinger%2C+James+D%3BSchulden%2C+Jeffrey+D%3BChavez%2C+Pollyanna%3BDiNenno%2C+Elizabeth+A&rft.aulast=Valverde&rft.aufirst=Eduardo&rft.date=2015-02-01&rft.volume=17&rft.issue=6&rft.spage=1826&rft.isbn=&rft.btitle=&rft.title=Journal+of+Immigrant+and+Minority+Health&rft.issn=15571912&rft_id=info:doi/10.1007%2Fs10903-014-0132-6 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-12-01 N1 - Number of references - 35 N1 - Last updated - 2015-12-23 N1 - SubjectsTermNotLitGenreText - Mobility; Immigrants; Intervention; Anal sex; Risk reduction; Infection; Drug abuse; Sexual behavior; Human immunodeficiency virus; Risk factors; Females; Ethnic groups; Migrants; Sexually transmitted diseases; USA DO - http://dx.doi.org/10.1007/s10903-014-0132-6 ER - TY - JOUR T1 - Physical Durability of Two Types of Long-Lasting Insecticidal Nets (LLINs) Three Years After a Mass LLIN Distribution Campaign in Mozambique, 2008-2011 AN - 1722173032; PQ0002108422 AB - We conducted a prospective evaluation to measure the physical durability of two brands of long-lasting insecticidal nets (LLINs) distributed during a campaign in 2008 in Nampula Province, Mozambique. Households with LLINs tagged during the campaign (6,000) were geo-located (34%) and a random sample was selected for each of 3 years of follow-up. The LLINs were evaluated in the field and a laboratory for presence of holes and a proportional hole index (pHI) was calculated following the World Health Organization guidelines. We performed 567 interviews (79.0%) and found 75.3% (72.1-78.4%) of households retained at least one LLIN after 3 years; the most common cause of attrition was damage beyond repair (51.0%). Hole damage was evident after 1 year, and increased by year. Olyset had a significantly greater mean number of holes and pH I compared with PermaNet 2.0 brand (all P values [< or =] 0.001). Additional information about LLIN durability is recommended to improve malaria control efforts. JF - American Journal of Tropical Medicine and Hygiene AU - Morgan, Juliette AU - Abilio, Ana Paula AU - Pondja, Maria do Rosario AU - Marrenjo, Dulcisaria AU - Luciano, Jacinta AU - Fernandes, Guilhermina AU - Sabindy, Samira AU - Wolkon, Adam AU - de Leon, Gabriel Ponce AU - Chan, Adeline AU - Eng, Jodi Vanden AD - President's Malaria Initiative, Malaria Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, gcp1@cdc.gov Y1 - 2015/02// PY - 2015 DA - February 2015 SP - 286 EP - 293 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 92 IS - 2 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts KW - Human diseases KW - Organizations KW - Attrition KW - Maintenance and repair KW - Guidelines KW - Malaria KW - Nets KW - Public health KW - Mozambique KW - Households KW - Toughness KW - Hygiene KW - pH effects KW - pH KW - J 02410:Animal Diseases KW - Q1 08604:Stock assessment and management KW - H 0500:General KW - Q5 08524:Public health, medicines, dangerous organisms KW - K 03420:Plant Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1722173032?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Physical+Durability+of+Two+Types+of+Long-Lasting+Insecticidal+Nets+%28LLINs%29+Three+Years+After+a+Mass+LLIN+Distribution+Campaign+in+Mozambique%2C+2008-2011&rft.au=Morgan%2C+Juliette%3BAbilio%2C+Ana+Paula%3BPondja%2C+Maria+do+Rosario%3BMarrenjo%2C+Dulcisaria%3BLuciano%2C+Jacinta%3BFernandes%2C+Guilhermina%3BSabindy%2C+Samira%3BWolkon%2C+Adam%3Bde+Leon%2C+Gabriel+Ponce%3BChan%2C+Adeline%3BEng%2C+Jodi+Vanden&rft.aulast=Morgan&rft.aufirst=Juliette&rft.date=2015-02-01&rft.volume=92&rft.issue=2&rft.spage=286&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0023 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Human diseases; Organizations; Maintenance and repair; Toughness; Malaria; Hygiene; Public health; pH effects; Nets; Attrition; Households; Guidelines; pH; Mozambique DO - http://dx.doi.org/10.4269/ajtmh.14-0023 ER - TY - JOUR T1 - Q Fever in the United States: Summary of Case Reports from Two National Surveillance Systems, 2000-2012 AN - 1722167597; PQ0002108415 AB - Q fever is a worldwide zoonosis historically associated with exposure to infected livestock. This study summarizes cases of Q fever, a notifiable disease in the United States, reported to the Centers for Disease Control and Prevention through two national surveillance systems with onset during 2000-2012. The overall incidence rate during this time was 0.38 cases per million persons per year. The reported case fatality rate was 2.0%, and the reported hospitalization rate was 62%. Most cases (61%) did not report exposure to cattle, goats, or sheep, suggesting that clinicians should consider Q fever even in the absence of livestock exposure. The prevalence of drinking raw milk among reported cases of Q fever (8.4%) was more than twice the national prevalence for the practice. Passive surveillance systems for Q fever are likely impacted by underreporting and underdiagnosis because of the nonspecific presentation of Q fever. JF - American Journal of Tropical Medicine and Hygiene AU - Dahlgren, F Scott AU - McQuiston, Jennifer H AU - Massung, Robert F AU - Anderson, Alicia D AD - Rickettsial Zoonoses Branch, Division of Vector-borne Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, iot0@cdc.gov Y1 - 2015/02// PY - 2015 DA - February 2015 SP - 247 EP - 255 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 92 IS - 2 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Drinking KW - USA KW - Milk KW - Case reports KW - Surveillance and enforcement KW - Disease control KW - Hygiene KW - Q fever KW - Livestock KW - J 02410:Animal Diseases KW - K 03400:Human Diseases KW - Q1 08604:Stock assessment and management KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1722167597?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=Practical+Application+of+Sequential+Multiplex+PCR+for+Routine+Pneumococcal+Serotype+Surveillance&rft.au=Hulkower%2C+R%3BGertz%2C+Jr%2C+R%3BRoundtree%2C+A%3BPimenta%2C+F%3BCarvalho%2C+M%3BFarley%2C+M%3BBeall%2C+B&rft.aulast=Hulkower&rft.aufirst=R&rft.date=2010-05-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Disease control; Surveillance and enforcement; Hygiene; Drinking; Milk; Case reports; Q fever; Livestock; USA DO - http://dx.doi.org/10.4269/ajtmh.14-0503 ER - TY - JOUR T1 - Risk for HIV following a diagnosis of syphilis, gonorrhoea or chlamydia: 328,456 women in Florida, 2000-2011 AN - 1712564778; PQ0001967279 AB - Several effective interventions are available for preventing HIV in women. Targeting interventions requires understanding their risk of acquiring HIV. We used surveillance data to estimate risks of HIV acquisition for 13-59-year-old women following a diagnosis of syphilis, gonorrhoea or chlamydia in Florida during 2000-2009. We excluded women reported with HIV before their STI, and measured HIV reported subsequent to STI (through 2011). Rates were compared to women with no reported STI. A total of 328,456 women had: syphilis (3325), gonorrhoea (67,784) or chlamydia (257,347). During 2,221,944 person-years of follow-up, 2118 of them were diagnosed with HIV. For women with no STI reported, during 64,763,832 person-years, 19,531 were reported with HIV. The crude rate of subsequent HIV diagnosis (per 100,000 person-years) was higher for women diagnosed with syphilis (597.9), gonorrhoea (171.3) or chlamydia (66.3) than women with no STI (30.2). Annual rates of HIV decreased over-all by 61.8% between 2001 and 2011. Women with syphilis or gonorrhoea were at highest risk for HIV and therefore might benefit from intensive counselling. However, they represented only a small fraction of the women who acquired HIV. Most cases of HIV infection among women occurred among the large group of women who were not at highest risk. JF - International Journal of STD & AIDS AU - Peterman, Thomas A AU - Newman, Daniel R AU - Maddox, Lorene AU - Schmitt, Karla AU - Shiver, Stacy AD - Division of STD Prevention, National Center for HIV, Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA, tap1@cdc.gov PY - 2015 SP - 113 EP - 119 PB - Sage Publications, Inc., 2455 Teller Road Thousand Oaks CA 91320 United States VL - 26 IS - 2 SN - 0956-4624, 0956-4624 KW - Health & Safety Science Abstracts; Microbiology Abstracts B: Bacteriology; Risk Abstracts; Virology & AIDS Abstracts KW - HIV KW - AIDS KW - sexually transmitted infection KW - HIV incidence KW - syphilis KW - gonorrhoea KW - chlamydia KW - women KW - epidemiology KW - prevention KW - North America KW - ASW, USA, Florida KW - Acquired immune deficiency syndrome KW - Data processing KW - Intervention KW - Infection KW - Human immunodeficiency virus KW - Risk factors KW - Treponema pallidum KW - Females KW - Syphilis KW - Sexually transmitted diseases KW - Chlamydia KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma KW - J 02400:Human Diseases KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1712564778?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+STD+%26+AIDS&rft.atitle=Risk+for+HIV+following+a+diagnosis+of+syphilis%2C+gonorrhoea+or+chlamydia%3A+328%2C456+women+in+Florida%2C+2000-2011&rft.au=Peterman%2C+Thomas+A%3BNewman%2C+Daniel+R%3BMaddox%2C+Lorene%3BSchmitt%2C+Karla%3BShiver%2C+Stacy&rft.aulast=Peterman&rft.aufirst=Thomas&rft.date=2015-02-01&rft.volume=26&rft.issue=2&rft.spage=113&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+STD+%26+AIDS&rft.issn=09564624&rft_id=info:doi/10.1177%2F0956462414531243 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-09-01 N1 - Last updated - 2015-12-23 N1 - SubjectsTermNotLitGenreText - Data processing; Risk factors; Infection; Syphilis; Acquired immune deficiency syndrome; Human immunodeficiency virus; Intervention; Females; Sexually transmitted diseases; Treponema pallidum; Chlamydia; ASW, USA, Florida DO - http://dx.doi.org/10.1177/0956462414531243 ER - TY - JOUR T1 - APPLICATION OF AN INFORMATICS-BASED DECISION-MAKING FRAMEWORK AND PROCESS TO THE ASSESSMENT OF RADIATION SAFETY IN NANOTECHNOLOGY AN - 1676360621; PQ0001237868 AB - The National Council on Radiation Protection and Measurements (NCRP) established NCRP Scientific Committee 2-6 to develop a report on the current state of knowledge and guidance for radiation safety programs involved with nanotechnology. Nanotechnology is the understanding and control of matter at the nanoscale, at dimensions between ~1 and 100 nm, where unique phenomena enable novel applications. While the full report is in preparation, this paper presents and applies an informatics-based decision-making framework and process through which the radiation protection community can anticipate that nano-enabled applications, processes, nanomaterials, and nanoparticles are likely to become present or are already present in radiation-related activities; recognize specific situations where environmental and worker safety, health, well-being, and productivity may be affected by nano-related activities; evaluate how radiation protection practices may need to be altered to improve protection; control information, interpretations, assumptions, and conclusions to implement scientifically sound decisions and actions; and confirm that desired protection outcomes have been achieved. This generally applicable framework and supporting process can be continuously applied to achieve health and safety at the convergence of nanotechnology and radiation-related activities. JF - Health Physics AU - Hoover, Mark D AU - Myers, David S AU - Cash, Leigh J AU - Guilmette, Raymond A AU - Kreyling, Wolfgang G AU - Oberdorster, Gunter AU - Smith, Rachel AU - Cassata, James R AU - Boecker, Bruce B AU - Grissom, Michael P AD - National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505-2888, mhoover1@cdc.gov Y1 - 2015/02// PY - 2015 DA - Feb 2015 SP - 179 EP - 194 PB - Williams & Wilkins, 351 W. Camden St. Baltimore MD 21201 United States VL - 108 IS - 2 SN - 0017-9078, 0017-9078 KW - Health & Safety Science Abstracts KW - National Council on Radiation Protection and Measurements KW - occupational safety KW - radiation protection KW - risk analysis KW - Radiation KW - Committees KW - Safety KW - Occupational safety KW - Councils KW - Nanotechnology KW - H 8000:Radiation Safety/Electrical Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1676360621?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+Physics&rft.atitle=APPLICATION+OF+AN+INFORMATICS-BASED+DECISION-MAKING+FRAMEWORK+AND+PROCESS+TO+THE+ASSESSMENT+OF+RADIATION+SAFETY+IN+NANOTECHNOLOGY&rft.au=Hoover%2C+Mark+D%3BMyers%2C+David+S%3BCash%2C+Leigh+J%3BGuilmette%2C+Raymond+A%3BKreyling%2C+Wolfgang+G%3BOberdorster%2C+Gunter%3BSmith%2C+Rachel%3BCassata%2C+James+R%3BBoecker%2C+Bruce+B%3BGrissom%2C+Michael+P&rft.aulast=Hoover&rft.aufirst=Mark&rft.date=2015-02-01&rft.volume=108&rft.issue=2&rft.spage=179&rft.isbn=&rft.btitle=&rft.title=Health+Physics&rft.issn=00179078&rft_id=info:doi/10.1097%2FHP.0000000000000250 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-04-01 N1 - Last updated - 2015-05-27 N1 - SubjectsTermNotLitGenreText - Radiation; Committees; Occupational safety; Safety; Councils; Nanotechnology DO - http://dx.doi.org/10.1097/HP.0000000000000250 ER - TY - JOUR T1 - Occupational exposures associated with severe exacerbation of asthma AN - 1668261708; PQ0001170312 AB - BACKGROUND: The exacerbation of asthma by workplace conditions is common, but little is known about which agents pose a risk. OBJECTIVE: We used data from an existing survey of adults with asthma to identify occupational exposures associated with severe exacerbation of asthma. DESIGN: Questionnaires were completed by 557 working adults with asthma. Severe exacerbation of asthma in the past 12 months was defined as asthma-related hospitalization, or reports of both unplanned asthma care and treatment with a short course of oral corticosteroids. Occupational exposures for the same time period were assessed using an asthma-specific job exposure matrix. We modeled severe exacerbation to yield prevalence ratios (PRs) for exposures while controlling for potential confounders. RESULTS: A total of 164 participants (29%) were positive for severe exacerbation, and 227 (40.8%) were assessed as being exposed to asthma agents at work. Elevated PRs were observed for several specific agents, notably the irritant subcategories of environmental tobacco smoke (PR 1.84, 95%CI 1.34-2.51) among all participants, inorganic dusts (PR 2.53, 95%CI 1.37-4.67) among men, and the low molecular weight subcategory of other highly reactive agents (PR 1.97, 95%CI 1.08-3.60) among women. CONCLUSION: Among working adults with asthma, severe exacerbation was associated with several occupational agents. JF - International Journal of Tuberculosis and Lung Disease AU - Henneberger, P K AU - Liang, X AU - Lillienberg, L AU - Dahlman-Hoglund, A AU - Toren, K AU - Andersson, E AD - Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, 1095 Willowdale Road, MS H2800, Morgantown, WV 26505, USA, pkh0@cdc.gov Y1 - 2015/02// PY - 2015 DA - Feb 2015 SP - 244 EP - 250 PB - International Union Against Tuberculosis and Lung Disease, 68 bvd Saint-Michel Paris 75006 France VL - 19 IS - 2 SN - 1027-3719, 1027-3719 KW - Risk Abstracts; Health & Safety Science Abstracts KW - work-exacerbated asthma KW - job-exposure matrix KW - occupational epidemiology KW - Risk assessment KW - Corticoids KW - Passive smoking KW - Mycobacterium KW - Lung KW - Asthma KW - Tuberculosis KW - Respiratory diseases KW - Occupational exposure KW - Dust KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1668261708?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Occupational+exposures+associated+with+severe+exacerbation+of+asthma&rft.au=Henneberger%2C+P+K%3BLiang%2C+X%3BLillienberg%2C+L%3BDahlman-Hoglund%2C+A%3BToren%2C+K%3BAndersson%2C+E&rft.aulast=Henneberger&rft.aufirst=P&rft.date=2015-02-01&rft.volume=19&rft.issue=2&rft.spage=244&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/10.5588%2Fijtld.14.0132 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Last updated - 2015-04-16 N1 - SubjectsTermNotLitGenreText - Risk assessment; Corticoids; Passive smoking; Lung; Asthma; Tuberculosis; Respiratory diseases; Dust; Occupational exposure; Mycobacterium DO - http://dx.doi.org/10.5588/ijtld.14.0132 ER - TY - JOUR T1 - National Survey of US Long-Haul Truck Driver Health and Injury: Health Behaviors AN - 1668247793; PQ0001261243 AB - Objective: To compare selected health behaviors and body mass index (modifiable risk factors) of US long-haul truck drivers to the US working population by sex. Methods: The National Survey of US Long-Haul Truck Driver Health and Injury interviewed a nationally representative sample of long-haul truck drivers (n = 1265) at truck stops. Age-adjusted results were compared with national health surveys. Results: Compared with US workers, drivers had significantly higher body mass index, current cigarette use, and pack-years of smoking; lower prevalence of annual influenza vaccination; and generally lower alcohol consumption. Physical activity level was low for most drivers, and 25% had never had their cholesterol levels tested. Conclusions: Working conditions common to long-haul trucking may create significant barriers to certain healthy behaviors; thus, transportation and health professionals should address the unique work environment when developing interventions for long-haul drivers. JF - Journal of Occupational and Environmental Medicine AU - Birdsey, Jan AU - Sieber, W Karl AU - Chen, Guang X AU - Hitchcock, Edward M AU - Lincoln, Jennifer E AU - Nakata, Akinori AU - Robinson, Cynthia F AU - Sweeney, Marie H AD - National Institute for Occupational Safety and Health, 4676 Columbia Pkwy, MS-R17, Cincinnati, OH 45226; Division of Surveillance, Hazard Evaluations, and Field Studies, JBirdsey@cdc.gov Y1 - 2015/02// PY - 2015 DA - Feb 2015 SP - 210 EP - 216 PB - Williams & Wilkins, 351 W. Camden St. Baltimore MD 21201 United States VL - 57 IS - 2 SN - 1076-2752, 1076-2752 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Alcohol KW - Cigarettes KW - Injuries KW - Physical activity KW - Body mass KW - Intervention KW - Cholesterol KW - Working conditions KW - Influenza KW - Transportation KW - Behavior KW - Risk factors KW - Trucks KW - Vaccines KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1668247793?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=National+Survey+of+US+Long-Haul+Truck+Driver+Health+and+Injury%3A+Health+Behaviors&rft.au=Birdsey%2C+Jan%3BSieber%2C+W+Karl%3BChen%2C+Guang+X%3BHitchcock%2C+Edward+M%3BLincoln%2C+Jennifer+E%3BNakata%2C+Akinori%3BRobinson%2C+Cynthia+F%3BSweeney%2C+Marie+H&rft.aulast=Birdsey&rft.aufirst=Jan&rft.date=2015-02-01&rft.volume=57&rft.issue=2&rft.spage=210&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0000000000000338 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Last updated - 2015-04-29 N1 - SubjectsTermNotLitGenreText - Alcohol; Injuries; Cigarettes; Body mass; Physical activity; Intervention; Cholesterol; Working conditions; Influenza; Transportation; Behavior; Risk factors; Trucks; Vaccines DO - http://dx.doi.org/10.1097/JOM.0000000000000338 ER - TY - JOUR T1 - Analysis of Neisseria gonorrhoeae Azithromycin Susceptibility in the United States by the Gonococcal Isolate Surveillance Project, 2005 to 2013 AN - 1660434829; PQ0001092219 AB - Azithromycin, administered with ceftriaxone, is recommended by the CDC for the treatment of gonorrhea. Many experts have expressed concern about the ease with which Neisseria gonorrhoeae can acquire macrolide resistance. We sought to describe gonococcal azithromycin susceptibility in the United States and to determine whether azithromycin susceptibility has changed over time. We analyzed data from 2005 to 2013 from the Gonococcal Isolate Surveillance Project, a CDC-supported sentinel surveillance network that monitors gonococcal antimicrobial susceptibility. A total of 44,144 N. gonorrhoeae isolates were tested for azithromycin susceptibility by agar dilution methods. The overall azithromycin MIC50 was 0.25 mu g/ml, and the MIC90 was 0.5 mu g/ml. There were no overall temporal trends in geometric means. Isolates from men who had sex with men had significantly higher geometric mean MICs than isolates from men who had sex exclusively with women. The overall prevalence of reduced azithromycin susceptibility (MIC, greater than or equal to 2 mu g/ml) was 0.4% and varied by year from 0.3% (2006 and 2009) to 0.6% (2013). We did not find a clear temporal trend in gonococcal azithromycin MICs in the United States, and the prevalence of reduced azithromycin susceptibility remains low. These findings support the continued use of azithromycin in a combination therapy regimen for gonorrhea. JF - Antimicrobial Agents & Chemotherapy AU - Kirkcaldy, Robert D AU - Soge, Olusegun AU - Papp, John R AU - Hook, Edward W, III AU - Rio, Carlos del AU - Kubin, Grace AU - Weinstock, Hillard S AD - Division of STD Prevention, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Atlanta, Georgia, USA, rkirkcaldy@cdc.gov. Y1 - 2015/02// PY - 2015 DA - Feb 2015 SP - 998 EP - 1003 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 59 IS - 2 SN - 0066-4804, 0066-4804 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Agar KW - Data processing KW - Azithromycin KW - Gonorrhea KW - Ceftriaxone KW - Minimum inhibitory concentration KW - Neisseria gonorrhoeae KW - Sex KW - Antimicrobial agents KW - A 01340:Antibiotics & Antimicrobials KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1660434829?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Analysis+of+Neisseria+gonorrhoeae+Azithromycin+Susceptibility+in+the+United+States+by+the+Gonococcal+Isolate+Surveillance+Project%2C+2005+to+2013&rft.au=Kirkcaldy%2C+Robert+D%3BSoge%2C+Olusegun%3BPapp%2C+John+R%3BHook%2C+Edward+W%2C+III%3BRio%2C+Carlos+del%3BKubin%2C+Grace%3BWeinstock%2C+Hillard+S&rft.aulast=Kirkcaldy&rft.aufirst=Robert&rft.date=2015-02-01&rft.volume=59&rft.issue=2&rft.spage=998&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.04337-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Number of references - 41 N1 - Last updated - 2015-11-16 N1 - SubjectsTermNotLitGenreText - Agar; Data processing; Azithromycin; Gonorrhea; Ceftriaxone; Minimum inhibitory concentration; Antimicrobial agents; Sex; Neisseria gonorrhoeae DO - http://dx.doi.org/10.1128/AAC.04337-14 ER - TY - JOUR T1 - More than half of US youth consume seafood and most have blood mercury concentrations below the EPA reference level, 2009-2012. AN - 1652454159; 25644354 AB - Consuming seafood has health benefits, but seafood can also contain methylmercury, a neurotoxicant. Exposure to methylmercury affects children at different stages of brain development, including during adolescence. The objective was to examine seafood consumption and blood mercury concentrations in US youth. In the 2009-2012 NHANES, a cross-sectional nationally representative sample of the US population, seafood consumption in the past 30 d and blood mercury concentrations on the day of examination were collected from 5656 youth aged 1-19 y. Log-linear regression was used to examine the association between frequency of specific seafood consumption and blood mercury concentration, adjusting for race/Hispanic origin, sex, and age. In 2009-2012, 62.4% ± 1.4% (percent ± SE) of youth consumed any seafood in the preceding month; 38.4% ± 1.4% and 48.5% ± 1.5% reported consuming shellfish and fish, respectively. In 2009-2012, the geometric mean blood mercury concentration was 0.50 ± 0.02 μg/L among seafood consumers and 0.27 ± 0.01 μg/L among those who did not consume seafood. Less than 0.5% of youth had blood mercury concentrations ≥5.8 μg/L. In adjusted log-linear regression analysis, no significant associations were observed between frequency of breaded fish or catfish consumption and blood mercury concentrations, but frequency of consuming certain seafood types had significant positive association with blood mercury concentrations: high-mercury fish (swordfish and shark) [exponentiated β coefficient (expβ): 2.40; 95% CI: 1.23, 4.68]; salmon (expβ: 1.41; 95% CI: 1.26, 1.55); tuna (expβ: 1.38; 95% CI: 1.29, 1.45); crabs (expβ: 1.35; 95% CI: 1.17, 1.55); shrimp (expβ: 1.12; 95% CI: 1.05, 1.20), and all other seafood (expβ: 1.23; 95% CI: 1.17, 1.32). Age-stratified log-linear regression analyses produced similar results. Few US youth have blood mercury concentrations ≥5.8 μg/L, although more than half of US youth consumed seafood in the past month. © 2015 American Society for Nutrition. JF - The Journal of nutrition AU - Nielsen, Samara Joy AU - Aoki, Yutaka AU - Kit, Brian K AU - Ogden, Cynthia L AD - Division of Health and Nutrition Examination Surveys, National Center for Health Statistics, CDC, Hyattsville, MD; and wjf7@cdc.gov. ; Division of Health and Nutrition Examination Surveys, National Center for Health Statistics, CDC, Hyattsville, MD; and. ; Division of Health and Nutrition Examination Surveys, National Center for Health Statistics, CDC, Hyattsville, MD; and US Public Health Service, Rockville, MD. Y1 - 2015/02// PY - 2015 DA - February 2015 SP - 322 EP - 327 VL - 145 IS - 2 KW - Mercury KW - FXS1BY2PGL KW - Index Medicus KW - blood mercury KW - shellfish KW - seafood KW - fish KW - youth KW - United States KW - Young Adult KW - United States Environmental Protection Agency KW - Humans KW - Food Contamination -- analysis KW - Child KW - Nutrition Surveys KW - Child, Preschool KW - Risk Assessment KW - Infant KW - Cross-Sectional Studies KW - Adolescent KW - Female KW - Male KW - Nutrition Policy -- legislation & jurisprudence KW - Mercury -- blood KW - Environmental Exposure -- analysis KW - Seafood -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1652454159?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=52nd+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.atitle=Salmonellosis%3A+Recent+Multistate+Outbreak+Investigations&rft.au=Behravesh%2C+Casey&rft.aulast=Behravesh&rft.aufirst=Casey&rft.date=2012-09-09&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=52nd+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2015-03-23 N1 - Date created - 2015-02-03 N1 - Date revised - 2017-01-14 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.3945/jn.114.203786 ER - TY - JOUR T1 - Metals Exposures of Residents Living Near the Akaki River in Addis Ababa, Ethiopia: A Cross-Sectional Study AN - 1751230028; PQ0002408411 AB - Background . The Akaki River in Ethiopia has been found to contain elevated levels of several metals. Our objectives were to characterize metals exposures of residents living near the Akaki River and to assess metal levels in their drinking water. Methods . In 2011, we conducted a cross-sectional study of 101 households in Akaki-Kality subcity (near the Akaki River) and 50 households in Yeka subcity (distant to the Akaki River). One willing adult in each household provided urine, blood, and drinking water sample. Results . Urinary molybdenum (p<0.001), tungsten (p<0.001), lead (p<0.001), uranium (p<0.001), and mercury (p=0.049) were higher in Akaki-Kality participants compared to Yeka participants. Participants in both subcities had low urinary iodine; 45% met the World Health Organization (WHO) classification for being at risk of moderate iodine deficiency. In Yeka, 47% of households exceeded the WHO aesthetic-based reference value for manganese; in Akaki-Kality, only 2% of households exceeded this value (p<0.001). There was no correlation between metals levels in water samples and clinical specimens. Conclusions . Most of the exposures found during this investigation seem unlikely to cause acute health effects based on known toxic thresholds. However, toxicity data for many of these metals are very limited. JF - Journal of Environmental and Public Health AU - Yard, Ellen AU - Bayleyegn, Tesfaye AU - Abebe, Almaz AU - Mekonnen, Andualem AU - Murphy, Matthew AU - Caldwell, Kathleen L AU - Luce, Richard AU - Hunt, Danielle Rentz AU - Tesfaye, Kirubel AU - Abate, Moa AU - Assefa, Tsigereda AU - Abera, Firehiwot AU - Habte, Kifle AU - Chala, Feyissa AU - Lewis, Lauren AU - Kebede, Amha AD - Centers for Disease Control and Prevention, National Center for Environmental Health, Atlanta, GA 30341, USA, eyard@cdc.gov Y1 - 2015/01// PY - 2015 DA - January 2015 PB - Hindawi Publishing Corporation, P.O. Box 3079 Cuyahoga Falls OH 44223 United States VL - 2015 SN - 1687-9805, 1687-9805 KW - Environment Abstracts; Health & Safety Science Abstracts KW - Risk assessment KW - Rivers KW - Metals KW - Water sampling KW - Molybdenum KW - Toxicity KW - Lead KW - Ethiopia KW - Classification KW - Urine KW - Uranium KW - Households KW - Iodine KW - Drinking water KW - Manganese KW - H 3000:Environment and Ecology KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1751230028?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+and+Public+Health&rft.atitle=Metals+Exposures+of+Residents+Living+Near+the+Akaki+River+in+Addis+Ababa%2C+Ethiopia%3A+A+Cross-Sectional+Study&rft.au=Yard%2C+Ellen%3BBayleyegn%2C+Tesfaye%3BAbebe%2C+Almaz%3BMekonnen%2C+Andualem%3BMurphy%2C+Matthew%3BCaldwell%2C+Kathleen+L%3BLuce%2C+Richard%3BHunt%2C+Danielle+Rentz%3BTesfaye%2C+Kirubel%3BAbate%2C+Moa%3BAssefa%2C+Tsigereda%3BAbera%2C+Firehiwot%3BHabte%2C+Kifle%3BChala%2C+Feyissa%3BLewis%2C+Lauren%3BKebede%2C+Amha&rft.aulast=Yard&rft.aufirst=Ellen&rft.date=2015-01-01&rft.volume=2015&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+and+Public+Health&rft.issn=16879805&rft_id=info:doi/10.1155%2F2015%2F935297 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-12-01 N1 - Number of references - 1 N1 - Last updated - 2016-08-03 N1 - SubjectsTermNotLitGenreText - Rivers; Risk assessment; Metals; Water sampling; Molybdenum; Toxicity; Lead; Classification; Urine; Households; Uranium; Iodine; Drinking water; Manganese; Ethiopia DO - http://dx.doi.org/10.1155/2015/935297 ER - TY - JOUR T1 - Comparison of Monkeypox Virus Clade Kinetics and Pathology within the Prairie Dog Animal Model Using a Serial Sacrifice Study Design AN - 1722179038; PQ0002026604 AB - Monkeypox virus (MPXV) infection of the prairie dog is valuable to studying systemic orthopoxvirus disease. To further characterize differences in MPXV clade pathogenesis, groups of prairie dogs were intranasally infected (8 super(103) p.f.u.) with Congo Basin (CB) or West African (WA) MPXV, and 28 tissues were harvested on days 2, 4, 6, 9, 12, 17, and 24 postinfection. Samples were evaluated for the presence of virus and gross and microscopic lesions. Virus was recovered from nasal mucosa, oropharyngeal lymph nodes, and spleen earlier in CB challenged animals (day 4) than WA challenged animals (day 6). For both groups, primary viremia (indicated by viral DNA) was seen on days 6-9 through day 17. CB MPXV spread more rapidly, accumulated to greater levels, and caused greater morbidity in animals compared to WA MPXV. Histopathology and immunohistochemistry (IHC) findings, however, were similar. Two animals that succumbed to disease demonstrated abundant viral antigen in all organs tested, except for brain. Dual-IHC staining of select liver and spleen sections showed that apoptotic cells (identified by TUNEL) tended to colocalize with poxvirus antigen. Interestingly splenocytes were labelled positive for apoptosis more often than hepatocytes in both MPXV groups. These findings allow for further characterization of differences between MPXV clade pathogenesis, including identifying sites that are important during early viral replication and cellular response to viral infection. JF - BioMed Research International AU - Hutson, Christina L AU - Carroll, Darin S AU - Gallardo-Romero, Nadia AU - Drew, Clifton AU - Zaki, Sherif R AU - Nagy, Tamas AU - Hughes, Christine AU - Olson, Victoria A AU - Sanders, Jeanine AU - Patel, Nishi AU - Smith, Scott K AU - Keckler, MShannon AU - Karem, Kevin AU - Damon, Inger K AD - Centers for Disease Control and Prevention, Poxvirus and Rabies Branch, Atlanta, GA 30333, USA, zuu6@cdc.gov Y1 - 2015/01// PY - 2015 DA - January 2015 PB - Hindawi Publishing Corporation, P.O. Box 3079 Cuyahoga Falls OH 44223 United States VL - 2015 SN - 2314-6133, 2314-6133 KW - Virology & AIDS Abstracts; Biotechnology and Bioengineering Abstracts KW - Orthopoxvirus KW - Monkeypox KW - Apoptosis KW - Replication KW - Hepatocytes KW - Mucosa KW - Animal models KW - Brain KW - Basins KW - Spleen KW - Infection KW - Morbidity KW - Lymph nodes KW - Splenocytes KW - Poxvirus KW - Kinetics KW - Liver KW - DNA KW - Viremia KW - Immunohistochemistry KW - Monkeypox virus KW - V 22320:Replication KW - W 30900:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1722179038?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=BioMed+Research+International&rft.atitle=Comparison+of+Monkeypox+Virus+Clade+Kinetics+and+Pathology+within+the+Prairie+Dog+Animal+Model+Using+a+Serial+Sacrifice+Study+Design&rft.au=Hutson%2C+Christina+L%3BCarroll%2C+Darin+S%3BGallardo-Romero%2C+Nadia%3BDrew%2C+Clifton%3BZaki%2C+Sherif+R%3BNagy%2C+Tamas%3BHughes%2C+Christine%3BOlson%2C+Victoria+A%3BSanders%2C+Jeanine%3BPatel%2C+Nishi%3BSmith%2C+Scott+K%3BKeckler%2C+MShannon%3BKarem%2C+Kevin%3BDamon%2C+Inger+K&rft.aulast=Hutson&rft.aufirst=Christina&rft.date=2015-01-01&rft.volume=2015&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=BioMed+Research+International&rft.issn=23146133&rft_id=info:doi/10.1155%2F2015%2F965710 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-05-13 N1 - SubjectsTermNotLitGenreText - Monkeypox; Apoptosis; Hepatocytes; Replication; Mucosa; Brain; Animal models; Spleen; Basins; Infection; Lymph nodes; Morbidity; Splenocytes; Kinetics; DNA; Liver; Viremia; Immunohistochemistry; Orthopoxvirus; Poxvirus; Monkeypox virus DO - http://dx.doi.org/10.1155/2015/965710 ER - TY - JOUR T1 - Molecular Differentiation of Treponema pallidum Subspecies in Skin Ulceration Clinically Suspected as Yaws in Vanuatu Using Real-Time Multiplex PCR and Serological Methods AN - 1722168349; PQ0002059456 AB - We developed a TaqMan-based real-time quadriplex polymerase chain reaction (PCR) to simultaneously detect Treponema pallidum subspecies pallidum, T. pallidum subsp. pertenue, and T. pallidum subsp. endemicum, the causative agents of venereal syphilis, yaws, and bejel, respectively. The PCR assay was applied to samples from skin ulcerations of clinically presumptive yaws cases among children on Tanna Island, Vanuatu. Another real-time triplex PCR was used to screen for the point mutations in the 23S rRNA genes that have previously been associated with azithromycin resistance in T. pallidum subsp. pallidum strains. Seropositivity by the classical syphilis serological tests was 35.5% among children with skin ulcerations clinically suspected with yaws, whereas the presence of T. pallidum subsp. pertenue DNA was only found in lesions from 15.5% of children. No evidence of T. pallidum subsp. pertenue infection, by either PCR or serology was found in ~59% of cases indicating alternative causes of yaws-like lesions in this endemic area. JF - American Journal of Tropical Medicine and Hygiene AU - Chi, Kai-Hua AU - Danavall, Damien AU - Taleo, Fasihah AU - Pillay, Allan AU - Ye, Tun AU - Nachamkin, Eli AU - Kool, Jacob L AU - Fegan, David AU - Asiedu, Kingsley AU - Vestergaard, Lasse S AU - Ballard, Ronald C AU - Chen, Cheng-Yen AD - Laboratory Reference and Research Branch, Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and Tuberculosis Prevention, Atlanta, Georgia, cychen@cdc.gov Y1 - 2015/01// PY - 2015 DA - January 2015 SP - 134 EP - 138 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 92 IS - 1 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - rRNA 23S KW - Nucleotide sequence KW - Yawing KW - ISEW, Pacific, Vanuatu KW - Infection KW - Serological tests KW - Serology KW - Differentiation KW - rRNA KW - Endemic species KW - Serological studies KW - Islands KW - Yaws KW - Azithromycin KW - Treponema pallidum KW - Polymerase chain reaction KW - Syphilis KW - Skin KW - Mutations KW - Point mutation KW - Children KW - Strains KW - Globus pallidus KW - DNA KW - Hygiene KW - K 03400:Human Diseases KW - Q1 08484:Species interactions: parasites and diseases KW - J 02400:Human Diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1722168349?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Molecular+Differentiation+of+Treponema+pallidum+Subspecies+in+Skin+Ulceration+Clinically+Suspected+as+Yaws+in+Vanuatu+Using+Real-Time+Multiplex+PCR+and+Serological+Methods&rft.au=Chi%2C+Kai-Hua%3BDanavall%2C+Damien%3BTaleo%2C+Fasihah%3BPillay%2C+Allan%3BYe%2C+Tun%3BNachamkin%2C+Eli%3BKool%2C+Jacob+L%3BFegan%2C+David%3BAsiedu%2C+Kingsley%3BVestergaard%2C+Lasse+S%3BBallard%2C+Ronald+C%3BChen%2C+Cheng-Yen&rft.aulast=Chi&rft.aufirst=Kai-Hua&rft.date=2015-01-01&rft.volume=92&rft.issue=1&rft.spage=134&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0459 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Serological studies; Endemic species; Mutations; Nucleotide sequence; Yawing; DNA; Polymerase chain reaction; Strains; Hygiene; Skin; rRNA 23S; Point mutation; Serological tests; Children; Infection; Serology; rRNA; Differentiation; Islands; Yaws; Azithromycin; Globus pallidus; Syphilis; Treponema pallidum; ISEW, Pacific, Vanuatu DO - http://dx.doi.org/10.4269/ajtmh.14-0459 ER - TY - JOUR T1 - Chikungunya Virus Infections Among Travelers-United States, 2010-2013 AN - 1722164278; PQ0002059448 AB - Chikungunya virus is an emerging threat to the United States because humans are amplifying hosts and competent mosquito vectors are present in many regions of the country. We identified laboratory-confirmed chikungunya virus infections with diagnostic testing performed in the United States from 2010 through 2013. We described the epidemiology of these cases and determined which were reported to ArboNET. From 2010 through 2013, 115 laboratory-confirmed chikungunya virus infections were identified. Among 55 cases with known travel history, 53 (96%) reported travel to Asia and 2 (4%) to Africa. No locally-acquired infections were identified. Six patients had detectable viremia after returning to the United States. Only 21% of identified cases were reported to ArboNET, with a median of 72 days between illness onset and reporting. Given the risk of introduction into the United States, healthcare providers and public health officials should be educated about the recognition, diagnosis, and timely reporting of chikungunya virus disease cases. JF - American Journal of Tropical Medicine and Hygiene AU - Lindsey, Nicole P AU - Prince, Harry E AU - Kosoy, Olga AU - Laven, Janeen AU - Messenger, Sharon AU - Staples, J Erin AU - Fischer, Marc AD - Arboviral Diseases Branch, Centers for Disease Control and Prevention, Fort Collins, Colorado, nplindsey@cdc.gov Y1 - 2015/01// PY - 2015 DA - January 2015 SP - 82 EP - 87 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 92 IS - 1 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Risk Abstracts; Virology & AIDS Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts KW - Travel KW - Historical account KW - Chikungunya virus KW - Vectors KW - Hosts KW - Infection KW - Medical personnel KW - Public health KW - Disease transmission KW - USA KW - Epidemiology KW - Africa KW - Viremia KW - Asia KW - Hygiene KW - Aquatic insects KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - K 03400:Human Diseases KW - Q1 08423:Behaviour KW - J 02400:Human Diseases KW - R2 23060:Medical and environmental health KW - Q5 08524:Public health, medicines, dangerous organisms KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1722164278?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Chikungunya+Virus+Infections+Among+Travelers-United+States%2C+2010-2013&rft.au=Lindsey%2C+Nicole+P%3BPrince%2C+Harry+E%3BKosoy%2C+Olga%3BLaven%2C+Janeen%3BMessenger%2C+Sharon%3BStaples%2C+J+Erin%3BFischer%2C+Marc&rft.aulast=Lindsey&rft.aufirst=Nicole&rft.date=2015-01-01&rft.volume=92&rft.issue=1&rft.spage=82&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0442 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Epidemiology; Hosts; Hygiene; Aquatic insects; Disease transmission; Public health; Travel; Vectors; Viremia; Infection; Historical account; Medical personnel; Chikungunya virus; USA; Africa; Asia DO - http://dx.doi.org/10.4269/ajtmh.14-0442 ER - TY - JOUR T1 - Erythema multiforme after orf virus infection: a report of two cases and literature review AN - 1668251925; PQ0001225870 AB - Orf virus has a worldwide distribution among sheep and goats. The hypersensitivity reaction erythema multiforme (EM) is a known complication of orf infection in humans; however, its occurrence is poorly understood and has not been extensively reviewed. We present two unrelated cases of orf-associated EM, and a review of the literature, highlighting important clinical, epidemiological and immunological aspects of this condition. Orf and its associated complications can occur in rural areas, as well as urban settings, where it is less well-known, through religious or cultural practices involving animal slaughter. Obtaining a history of animal exposures from patients with lesions suspicious for orf and secondary skin eruptions can guide diagnosis and identification of the inciting immune stimulus. Determining the pathophysiology and relative contribution of host and viral factors contributing to EM and other orf-associated hypersensitivity reactions could facilitate the identification of risk factors and inform treatment decisions. JF - Epidemiology and Infection AU - Joseph, R H AU - Haddad, F A AU - Matthews, Al AU - Maroufi, A AU - Monroe, B AU - Reynolds, M AD - Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA, rjoseph@cdc.gov Y1 - 2015/01// PY - 2015 DA - January 2015 SP - 385 EP - 390 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 143 IS - 2 SN - 0950-2688, 0950-2688 KW - Virology & AIDS Abstracts; Risk Abstracts KW - Historical account KW - Culture KW - Erythema multiforme KW - Eruptions KW - Skin KW - Complications KW - Sheep KW - Infection KW - Immunological aspects KW - Hypersensitivity KW - Literature reviews KW - Orf virus KW - Reviews KW - Risk factors KW - Lesions KW - Slaughter KW - Rural areas KW - Urban areas KW - V 22410:Animal Diseases KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1668251925?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Erythema+multiforme+after+orf+virus+infection%3A+a+report+of+two+cases+and+literature+review&rft.au=Joseph%2C+R+H%3BHaddad%2C+F+A%3BMatthews%2C+Al%3BMaroufi%2C+A%3BMonroe%2C+B%3BReynolds%2C+M&rft.aulast=Joseph&rft.aufirst=R&rft.date=2015-01-01&rft.volume=143&rft.issue=2&rft.spage=385&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268814000879 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Number of references - 30 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Hypersensitivity; Erythema multiforme; Skin; Literature reviews; Risk factors; Slaughter; Infection; Immunological aspects; Historical account; Culture; Eruptions; Complications; Sheep; Reviews; Lesions; Urban areas; Rural areas; Orf virus DO - http://dx.doi.org/10.1017/S0950268814000879 ER - TY - JOUR T1 - Use of laboratory reports as predictors of West Nile virus disease cases, Texas, 2008-2012 AN - 1668250807; PQ0001225877 AB - We evaluated laboratory reports as early indicators of West Nile virus (WNV) disease cases in Texas. We compared WNV laboratory results in the National Electronic Disease Surveillance System Base System (NBS) to WNV disease cases reported to the state health department from 2008 to 2012. We calculated sensitivity and positive predictive value (PPV) of NBS reports, estimated the number of disease cases expected per laboratory report, and determined lead and lag times. The sensitivity and PPV of NBS laboratory reports were 86% and 77%, respectively. For every 10 positive laboratory reports, we expect 9.0 (95% confidence interval 8.9-9.2) reported disease cases. Laboratory reports preceded case reports with a lead time of 7 days. Electronic laboratory reports provided longer lead times than manually entered reports (P < 0.01). NBS laboratory reports are useful estimates of future reported WNV disease cases and may provide timely information for planning public health interventions. JF - Epidemiology and Infection AU - Yendell, S J AU - Taylor, J AU - Biggerstaff, B J AU - TABONY, L AU - Staples, Je AU - Fischer, M AD - Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, CO, USA, mfischer@cdc.gov Y1 - 2015/01// PY - 2015 DA - January 2015 SP - 419 EP - 426 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 143 IS - 2 SN - 0950-2688, 0950-2688 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Sensitivity KW - Case reports KW - Intervention KW - USA, Texas KW - West Nile virus KW - Lead KW - Public health KW - H 12000:Epidemiology and Public Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1668250807?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Use+of+laboratory+reports+as+predictors+of+West+Nile+virus+disease+cases%2C+Texas%2C+2008-2012&rft.au=Yendell%2C+S+J%3BTaylor%2C+J%3BBiggerstaff%2C+B+J%3BTABONY%2C+L%3BStaples%2C+Je%3BFischer%2C+M&rft.aulast=Yendell&rft.aufirst=S&rft.date=2015-01-01&rft.volume=143&rft.issue=2&rft.spage=419&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268814000909 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Number of references - 14 N1 - Last updated - 2016-03-30 N1 - SubjectsTermNotLitGenreText - Case reports; Lead; Public health; Sensitivity; Intervention; West Nile virus; USA, Texas DO - http://dx.doi.org/10.1017/S0950268814000909 ER - TY - JOUR T1 - Correlates of Sexual Risk for HIV Among US-Born and Foreign-Born Latino Men Who Have Sex with Men (MSM): An Analysis from the Brothers y Hermanos Study AN - 1665159868 AB - Little research has been conducted to examine whether correlates of sexual risk vary by nativity among Latino men who have sex with men (MSM). We used cross sectional data collected from 870 Latino MSM recruited with respondent-driven sampling techniques. For each sub-sample (US-born and foreign-born), we assessed the association between each of the potential correlates (substance use, acculturation, social support, and social discrimination) and sexual risk behavior. Illicit drug use was associated with increased odds of sexual risk behavior in both US-born (OR = 2.17, 95 % CI 1.17–4.03) and foreign-born (OR = 1.86, 1.14–3.05) subgroups. Multivariate correlates specific to foreign-born men included binge drinking (OR = 1.91, 1.17–3.14), 15 years or longer spent in the US (OR = 1.79, 1.06–3.03) and exposure to social discrimination (OR = 2.02, 1.03–3.99). Given the diversity of Latino MSM, information from research that identifies both common and different HIV risk factors across subgroups of Latino MSM may help better tailor HIV prevention programs. JF - Journal of Immigrant and Minority Health AU - Mizuno, Yuko AU - Borkowf, Craig B AU - Ayala, George AU - Carballo-Diéguez, Alex AU - Millett, Gregorio A AD - Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road, NE Mail Stop E37, Atlanta, GA, 30333, USA ymizuno@cdc.gov ymizuno@cdc.gov; The Global Forum on MSM and HIV, Oakland, CA, USA ; New York State Psychiatric Institute, New York, NY, USA, Columbia University, New York, NY, USA ; Centers for Disease Control and Prevention, Washington, DC, USA ; Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road, NE Mail Stop E37, Atlanta, GA, 30333, USA Y1 - 2015/01// PY - 2015 DA - Jan 2015 SP - 47 EP - 55 CY - New York PB - Springer Science & Business Media VL - 17 IS - 1 SN - 1557-1912 KW - Medical Sciences KW - Acculturation KW - Sex education KW - Social support KW - Substance abuse KW - Binge drinking KW - Brothers KW - Discrimination KW - Diversity KW - Drug abuse KW - HIV KW - Homosexuals KW - Men KW - Preventive health care KW - Preventive programmes KW - Risk behaviour KW - Risk factors KW - Safe sexual practices KW - Sampling KW - United States--US UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1665159868?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Immigrant+and+Minority+Health&rft.atitle=Correlates+of+Sexual+Risk+for+HIV+Among+US-Born+and+Foreign-Born+Latino+Men+Who+Have+Sex+with+Men+%28MSM%29%3A+An+Analysis+from+the+Brothers+y+Hermanos+Study&rft.au=Mizuno%2C+Yuko%3BBorkowf%2C+Craig+B%3BAyala%2C+George%3BCarballo-Di%C3%A9guez%2C+Alex%3BMillett%2C+Gregorio+A&rft.aulast=Mizuno&rft.aufirst=Yuko&rft.date=2015-01-01&rft.volume=17&rft.issue=1&rft.spage=47&rft.isbn=&rft.btitle=&rft.title=Journal+of+Immigrant+and+Minority+Health&rft.issn=15571912&rft_id=info:doi/10.1007%2Fs10903-013-9894-5 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2015-02-05 N1 - Last updated - 2016-05-16 N1 - SubjectsTermNotLitGenreText - United States--US DO - http://dx.doi.org/10.1007/s10903-013-9894-5 ER - TY - JOUR T1 - Tuberculosis and excess alcohol use in the United States, 1997-2012 AN - 1660425467; PQ0001064063 AB - BACKGROUND: Excess alcohol use among tuberculosis (TB) patients complicates TB control strategies. OBJECTIVES: To characterize the role of excess alcohol use in TB control, we describe the epidemiology of excess alcohol use and TB in the United States among those aged [> or =, slanted] 15 years. DESIGN: Using data reported to the National Tuberculosis Surveillance System, 1997-2012, we examined associations between excess alcohol use and TB treatment outcomes and markers for increased transmission (involvement in a local genotype cluster of cases) using multivariate logistic regression. We used Cox proportional hazards regression analysis to examine the relationship between excess alcohol use and the rate of conversion from positive to negative in sputum culture results. RESULTS: Excess alcohol use was documented for 31207 (15.1%) of 207307 patients. Prevalence of excess alcohol use was greater among male patients (20.6%) and US-born patients (24.6%). Excess alcohol use was associated with a positive sputum smear result (aOR 1.23, 95%CI 1.18-1.28) and death during treatment (vs. completion of treatment) (aOR 1.16, 95% CI 1.10-1.22). The rate of culture conversion was higher among patients without excess alcohol use (adjusted hazard ratio 1.20, 95%CI 1.18-1.23). CONCLUSIONS: Excess alcohol use was common among patients with TB, and was associated with TB transmission, lower rates of sputum culture conversion and greater mortality. JF - International Journal of Tuberculosis and Lung Disease AU - Volkmann, T AU - Moonan, P K AU - Miramontes, R AU - Oeltmann, J E AD - Epidemic Intelligence Service, assigned to Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, xdh4@cdc.gov Y1 - 2015/01// PY - 2015 DA - Jan 2015 SP - 111 EP - 119 PB - International Union Against Tuberculosis and Lung Disease, 68 bvd Saint-Michel Paris 75006 France VL - 19 IS - 1 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology KW - substance use KW - Mycobacterium tuberculosis KW - directly observed therapy KW - sputum culture KW - culture conversion KW - Mortality KW - Data processing KW - Epidemiology KW - Mycobacterium KW - alcohols KW - Lung diseases KW - Regression analysis KW - Tuberculosis KW - Sputum KW - Genotypes KW - Disease transmission KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1660425467?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Tuberculosis+and+excess+alcohol+use+in+the+United+States%2C+1997-2012&rft.au=Volkmann%2C+T%3BMoonan%2C+P+K%3BMiramontes%2C+R%3BOeltmann%2C+J+E&rft.aulast=Volkmann&rft.aufirst=T&rft.date=2015-01-01&rft.volume=19&rft.issue=1&rft.spage=111&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/10.5588%2Fijtld.14.0516 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Last updated - 2015-11-16 N1 - SubjectsTermNotLitGenreText - Mortality; Data processing; Epidemiology; Regression analysis; Lung diseases; alcohols; Tuberculosis; Genotypes; Sputum; Disease transmission; Mycobacterium DO - http://dx.doi.org/10.5588/ijtld.14.0516 ER - TY - JOUR T1 - Debilitating Lung Disease Among Surface Coal Miners With No Underground Mining Tenure AN - 1660394415; PQ0001169716 AB - Objective: To characterize exposure histories and respiratory disease among surface coal miners identified with progressive massive fibrosis from a 2010 to 2011 pneumoconiosis survey. Methods: Job history, tenure, and radiograph interpretations were verified. Previous radiographs were reviewed when available. Telephone follow-up sought additional work and medical history information. Results: Among eight miners who worked as drill operators or blasters for most of their tenure (median, 35.5 years), two reported poor dust control practices, working in visible dust clouds as recently as 2012. Chest radiographs progressed to progressive massive fibrosis in as few as 11 years. One miner's lung biopsy demonstrated fibrosis and interstitial accumulation of macrophages containing abundant silica, aluminum silicate, and titanium dust particles. Conclusions: Overexposure to respirable silica resulted in progressive massive fibrosis among current surface coal miners with no underground mining tenure. Inadequate dust control during drilling/blasting is likely an important etiologic factor. JF - Journal of Occupational and Environmental Medicine AU - Halldin, Cara N AU - Reed, William R AU - Joy, Gerald J AU - Colinet, Jay F AU - Rider, James P AU - Petsonk, Edward L AU - Abraham, Jerrold L AU - Wolfe, Anita L AU - Storey, Eileen AU - Laney, A Scott AD - Surveillance Branch, Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WVa, challdin@cdc.gov Y1 - 2015/01// PY - 2015 DA - Jan 2015 SP - 62 EP - 67 PB - Williams & Wilkins, 351 W. Camden St. Baltimore MD 21201 United States VL - 57 IS - 1 SN - 1076-2752, 1076-2752 KW - Health & Safety Science Abstracts KW - Historical account KW - Dust clouds KW - Occupational safety KW - Pneumoconiosis KW - Respiratory diseases KW - Coal KW - Particulates KW - Dust KW - Silica KW - Lung KW - Reviews KW - Aluminum KW - Blasting KW - Mining KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1660394415?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Debilitating+Lung+Disease+Among+Surface+Coal+Miners+With+No+Underground+Mining+Tenure&rft.au=Halldin%2C+Cara+N%3BReed%2C+William+R%3BJoy%2C+Gerald+J%3BColinet%2C+Jay+F%3BRider%2C+James+P%3BPetsonk%2C+Edward+L%3BAbraham%2C+Jerrold+L%3BWolfe%2C+Anita+L%3BStorey%2C+Eileen%3BLaney%2C+A+Scott&rft.aulast=Halldin&rft.aufirst=Cara&rft.date=2015-01-01&rft.volume=57&rft.issue=1&rft.spage=62&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0000000000000302 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Last updated - 2015-04-16 N1 - SubjectsTermNotLitGenreText - Historical account; Occupational safety; Dust clouds; Pneumoconiosis; Particulates; Coal; Respiratory diseases; Dust; Silica; Lung; Reviews; Aluminum; Blasting; Mining DO - http://dx.doi.org/10.1097/JOM.0000000000000302 ER - TY - JOUR T1 - Individual and Community-Level Determinants of Mental and Physical Health After the Deepwater Horizon Oil Spill: Findings from the Gulf States Population Survey AN - 1660388946; 21314108 AB - The 2010 Deepwater Horizon oil spill had enormous consequences on the environment. Prevalence of mental and physical health conditions among Gulf residents after the disaster, however, are still being assessed. The Gulf State Population Survey (GSPS) was a representative survey of 38,361 residents in four Gulf States and was conducted from December 2010 to December 2011. Analysis of the GSPS data showed that differences in individual characteristics and direct or indirect exposure to the disaster drove the individual-level variation in health outcomes (mental distress, physical distress, and depression). Direct exposure to the disaster itself was the most important determinant of health after this event. Selected county-level characteristics were not found to be significantly associated with any of our health indicators of interest. This study suggests that in the context of an overwhelming event, persons who are most directly affected through direct exposure should be the primary focus of any public health intervention effort. JF - Journal of Behavioral Health Services and Research AU - Fan, Amy Z AU - Prescott, Marta R AU - Zhao, Guixiang AU - Gotway, Carol A AU - Galea, Sandro AD - Division of Behavioral Surveillance, Public Health Surveillance and Informatics Program Office, Office of Surveillance, Epidemiology and Laboratory Services, Centers for Disease Control and Prevention, Atlanta, GA, USA, afan@cdc.gov Y1 - 2015/01// PY - 2015 DA - Jan 2015 SP - 23 EP - 41 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 42 IS - 1 SN - 1094-3412, 1094-3412 KW - Health & Safety Science Abstracts KW - Depression KW - Disasters KW - Intervention KW - Oil spills KW - Public health KW - H 6000:Natural Disasters/Civil Defense/Emergency Management UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1660388946?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Behavioral+Health+Services+and+Research&rft.atitle=Individual+and+Community-Level+Determinants+of+Mental+and+Physical+Health+After+the+Deepwater+Horizon+Oil+Spill%3A+Findings+from+the+Gulf+States+Population+Survey&rft.au=Fan%2C+Amy+Z%3BPrescott%2C+Marta+R%3BZhao%2C+Guixiang%3BGotway%2C+Carol+A%3BGalea%2C+Sandro&rft.aulast=Fan&rft.aufirst=Amy&rft.date=2015-01-01&rft.volume=42&rft.issue=1&rft.spage=23&rft.isbn=&rft.btitle=&rft.title=Journal+of+Behavioral+Health+Services+and+Research&rft.issn=10943412&rft_id=info:doi/10.1007%2Fs11414-014-9418-7 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Number of references - 59 N1 - Last updated - 2015-04-02 N1 - SubjectsTermNotLitGenreText - Depression; Disasters; Intervention; Oil spills; Public health DO - http://dx.doi.org/10.1007/s11414-014-9418-7 ER - TY - JOUR T1 - Annual risk of tuberculous infection measured using serial skin testing, Orel Oblast, Russia, 1991-2005 AN - 1655746503; PQ0001064051 AB - OBJECTIVE: To compare trends in direct annual risk of tuberculous infection (ARTI) during 1991-2005 in relation to tuberculosis (TB) incidence and to indirect estimates of ARTI derived from the prevalence of tuberculin skin test (TST) positivity in schoolchildren in Orel Oblast, Russia. DESIGN: In 2005, we abstracted annual TST results and vaccination histories from a representative sample of schoolchildren in Orel Oblast, Russia, where bacille Calmette-Guerin (BCG) vaccination and annual TST of children are nearly universal. We calculated direct ARTI based on the percentage of children tested with TST conversions each year, excluding conversions following BCG vaccination. RESULTS: We analysed records from 13 206 children, with a median of 10 recorded TST results per child. The ARTI increased from 0.2% in 1991 to 1.6% in 2000, paralleling trends in TB incidence. Similar results were observed when the ARTI was estimated based on prevalence of infection among children aged 3-5 years using a 12 mm cut-off to define TST positivity. Results differed substantially when 10 or 15 mm cut-offs were used or when prevalence was determined among children aged 6-8 years. CONCLUSION: ARTI measured through TST conversion increased as TB incidence increased in Orel Oblast. ARTI measured through serial TSTs can thus provide an indicator of changing trends in TB incidence. JF - International Journal of Tuberculosis and Lung Disease AU - Yuen, C M AU - Krapivina, T M AU - Kazennyy, B Y AU - Kiryanova, E V AU - Aksenova, V A AU - Gordina, A AU - Finlay, A M AU - Cegielski, J P AD - Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, pcegielski@cdc.gov Y1 - 2015/01// PY - 2015 DA - Jan 2015 SP - 39 EP - 43 PB - International Union Against Tuberculosis and Lung Disease, 68 bvd Saint-Michel Paris 75006 France VL - 19 IS - 1 SN - 1027-3719, 1027-3719 KW - Health & Safety Science Abstracts; Risk Abstracts KW - tuberculous infection KW - tuberculin test KW - Russia KW - Health risks KW - Historical account KW - INW, Russia KW - Mycobacterium KW - Lung KW - Tuberculosis KW - Vaccines KW - Children KW - Infection KW - R2 23060:Medical and environmental health KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1655746503?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Annual+risk+of+tuberculous+infection+measured+using+serial+skin+testing%2C+Orel+Oblast%2C+Russia%2C+1991-2005&rft.au=Yuen%2C+C+M%3BKrapivina%2C+T+M%3BKazennyy%2C+B+Y%3BKiryanova%2C+E+V%3BAksenova%2C+V+A%3BGordina%2C+A%3BFinlay%2C+A+M%3BCegielski%2C+J+P&rft.aulast=Yuen&rft.aufirst=C&rft.date=2015-01-01&rft.volume=19&rft.issue=1&rft.spage=39&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/10.5588%2Fijtld.14.0445 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-02-01 N1 - Last updated - 2015-08-05 N1 - SubjectsTermNotLitGenreText - Historical account; Health risks; Lung; Tuberculosis; Vaccines; Infection; Children; Mycobacterium; INW, Russia; Russia DO - http://dx.doi.org/10.5588/ijtld.14.0445 ER - TY - JOUR T1 - Efficacy of Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine for Treatment of Uncomplicated Malaria in Children in Zaire and Uige Provinces, Angola AN - 1654694240; 21328196 AB - The development of resistance to antimalarials is a major challenge for global malaria control. Artemisinin-based combination therapies, the newest class of antimalarials, are used worldwide but there have been reports of artemisinin resistance in Southeast Asia. In February through May 2013, we conducted open-label, nonrandomized therapeutic efficacy studies of artemether-lumefantrine (AL) and dihydroartemisinin-piperaquine (DP) in Zaire and Uige Provinces in northern Angola. The parasitological and clinical responses to treatment in children with uncomplicated Plasmodium falciparum monoinfection were measured over 28 days, and the main outcome was a PCR-corrected adequate clinical and parasitological response (ACPR) proportion on day 28. Parasites from treatment failures were analyzed for the presence of putative molecular markers of resistance to lumefantrine and artemisinins, including the recently identified mutations in the K13 propeller gene. In the 320 children finishing the study, 25 treatment failures were observed: 24 in the AL arms and 1 in the DP arm. The PCR-corrected ACPR proportions on day 28 for AL were 88% (95% confidence interval [CI], 78 to 95%) in Zaire and 97% (91 to 100%) in Uige. For DP, the proportions were 100% (95 to 100%) in Zaire, and 100% (96 to 100%) in Uige. None of the treatment failures had molecular evidence of artemisinin resistance. In contrast, 91% of AL late-treatment failures had markers associated with lumefantrine resistance on the day of failure. The absence of molecular markers for artemisinin resistance and the observed efficacies of both drug combinations suggest no evidence of artemisinin resistance in northern Angola. There is evidence of increased lumefantrine resistance in Zaire, which should continue to be monitored. JF - Antimicrobial Agents & Chemotherapy AU - Plucinski, Mateusz M AU - Talundzic, Eldin AU - Morton, Lindsay AU - Dimbu, Pedro Rafael AU - Macaia, Aleixo Panzo AU - Fortes, Filomeno AU - Goldman, Ira AU - Lucchi, Naomi AU - Stennies, Gail AU - MacArthur, John R AD - Malaria Branch and President's Malaria Initiative, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, mplucinski@cdc.gov. Y1 - 2015/01// PY - 2015 DA - January 2015 SP - 437 EP - 443 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 59 IS - 1 SN - 0066-4804, 0066-4804 KW - Health & Safety Science Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Angola KW - Parasites KW - Human diseases KW - Chemotherapy KW - Nucleotide sequence KW - Malaria KW - ASE, Angola KW - Angola, Zaire KW - Public health KW - Polymerase chain reaction KW - Southeast Asia KW - Drugs KW - Mutations KW - Therapy KW - Plasmodium falciparum KW - Children KW - Antimicrobial agents KW - DNA KW - artemisinin KW - ISEW, Southeast Asia KW - Mutation KW - A 01340:Antibiotics & Antimicrobials KW - K 03400:Human Diseases KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08502:Methods and instruments KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1654694240?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Efficacy+of+Artemether-Lumefantrine+and+Dihydroartemisinin-Piperaquine+for+Treatment+of+Uncomplicated+Malaria+in+Children+in+Zaire+and+Uige+Provinces%2C+Angola&rft.au=Plucinski%2C+Mateusz+M%3BTalundzic%2C+Eldin%3BMorton%2C+Lindsay%3BDimbu%2C+Pedro+Rafael%3BMacaia%2C+Aleixo+Panzo%3BFortes%2C+Filomeno%3BGoldman%2C+Ira%3BLucchi%2C+Naomi%3BStennies%2C+Gail%3BMacArthur%2C+John+R&rft.aulast=Plucinski&rft.aufirst=Mateusz&rft.date=2015-01-01&rft.volume=59&rft.issue=1&rft.spage=437&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.04181-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-02-01 N1 - Number of references - 35 N1 - Last updated - 2016-02-04 N1 - SubjectsTermNotLitGenreText - Parasites; Human diseases; Mutations; Nucleotide sequence; Therapy; DNA; Polymerase chain reaction; Malaria; Public health; artemisinin; Children; Mutation; Chemotherapy; Drugs; Antimicrobial agents; Plasmodium falciparum; Angola; Southeast Asia; ISEW, Southeast Asia; ASE, Angola; Angola, Zaire DO - http://dx.doi.org/10.1128/AAC.04181-14 ER - TY - JOUR T1 - Determination of super(234) U/ super(238) U, super(235) U/ super(238) U and super(236) U/ super(238) U isotope ratios in urine using sector field inductively coupled plasma mass spectrometry AN - 1808660511; PQ0003214455 AB - Quantification of the isotopic composition of uranium in urine at low levels of concentration is important for assessing both military and civilian populations' exposures to uranium. However, until now there has been no convenient, precise method established for rapid determination of multiple uranium isotope ratios. Here, the authors report a new method to measure super(234) U/ super(238) U, super(235) U/ super(238) U and super(236) U/ super(238) U. It uses solid-phase chelation extraction (via TRU columns) of actinides from the urine matrix, followed by measurement using a magnetic sector field inductively coupled plasma mass spectrometer (SF-ICP-MS-Thermo Element XR) equipped with a high-efficiency nebulizer (Apex PFA microflow) and coupled with a membrane desolvating nebulizer system (Aridus II(TM)). This method provides rapid and reliable results and has been used successfully to analyse Certified Reference Materials. JF - Radiation Protection Dosimetry AU - Xiao, Ge AU - Jones, Robert L AU - Saunders, David AU - Caldwell, Kathleen L AD - Inorganic and Radiation Analytical Toxicology Branch, Centers for Disease Control and Prevention, 4770 Buford HWY, Mail Stop F50, Atlanta, GA 30341, USA, gxiao@cdc.gov Y1 - 2014/12// PY - 2014 DA - December 2014 SP - 618 EP - 624 PB - Oxford University Press, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 162 IS - 4 SN - 0144-8420, 0144-8420 KW - Environment Abstracts KW - Isotopes KW - Membranes KW - Radiation KW - Urine KW - Uranium KW - Chelation KW - Dosimetry KW - Mass spectrometry KW - Military KW - Actinides KW - ENA 14:Radiological Contamination UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808660511?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Radiation+Protection+Dosimetry&rft.atitle=Determination+of+super%28234%29+U%2F+super%28238%29+U%2C+super%28235%29+U%2F+super%28238%29+U+and+super%28236%29+U%2F+super%28238%29+U+isotope+ratios+in+urine+using+sector+field+inductively+coupled+plasma+mass+spectrometry&rft.au=Xiao%2C+Ge%3BJones%2C+Robert+L%3BSaunders%2C+David%3BCaldwell%2C+Kathleen+L&rft.aulast=Xiao&rft.aufirst=Ge&rft.date=2014-12-01&rft.volume=162&rft.issue=4&rft.spage=618&rft.isbn=&rft.btitle=&rft.title=Radiation+Protection+Dosimetry&rft.issn=01448420&rft_id=info:doi/10.1093%2Frpd%2Fncu023 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-08-04 N1 - SubjectsTermNotLitGenreText - Isotopes; Membranes; Radiation; Urine; Uranium; Dosimetry; Chelation; Mass spectrometry; Military; Actinides DO - http://dx.doi.org/10.1093/rpd/ncu023 ER - TY - JOUR T1 - Sustained, Area-Wide Control of Aedes aegypti Using CDC Autocidal Gravid Ovitraps AN - 1727681374; PQ0002140064 AB - We have shown that the Centers for Disease Control and Prevention (CDC) autocidal gravid ovitraps (AGO trap) reduced the Aedes aegypti population and prevented mosquito outbreaks in southern Puerto Rico. After showing treatment efficacy for 1 year, we deployed three traps per home in an area that formerly did not have traps and in a site that served as the intervention area. Two new areas were selected as reference sites to compare the density of Ae. aegypti without traps. We monitored mosquitoes and weather every week in all four sites. The hypotheses were the density of Ae. aegypti in the former reference area converges to the low levels observed in the intervention area, and mosquito density in both areas having control traps is lower than in the new reference areas. Mosquito density in the former reference area decreased 79% and mosquito density in the new reference areas was 88% greater than in the intervention areas. JF - American Journal of Tropical Medicine and Hygiene AU - Barrera, Roberto AU - Amador, Manuel AU - Acevedo, Veronica AU - Hemme, Ryan R AU - Felix, Gilberto AD - Entomology and Ecology Activity, Dengue Branch, Centers for Disease Control and Prevention, Calle Canada, San Juan, Puerto Rico, rbarrera@cdc.gov Y1 - 2014/12// PY - 2014 DA - December 2014 SP - 1269 EP - 1276 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 91 IS - 6 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Entomology Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Weather KW - Aedes aegypti KW - ASW, Caribbean Sea, Greater Antilles, Puerto Rico KW - Disease control KW - Pest control KW - Hygiene KW - Aquatic insects KW - K 03410:Animal Diseases KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - J 02400:Human Diseases KW - Q1 08485:Species interactions: pests and control KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727681374?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Sustained%2C+Area-Wide+Control+of+Aedes+aegypti+Using+CDC+Autocidal+Gravid+Ovitraps&rft.au=Barrera%2C+Roberto%3BAmador%2C+Manuel%3BAcevedo%2C+Veronica%3BHemme%2C+Ryan+R%3BFelix%2C+Gilberto&rft.aulast=Barrera&rft.aufirst=Roberto&rft.date=2014-12-01&rft.volume=91&rft.issue=6&rft.spage=1269&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0426 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Disease control; Pest control; Hygiene; Aquatic insects; Weather; Aedes aegypti; ASW, Caribbean Sea, Greater Antilles, Puerto Rico DO - http://dx.doi.org/10.4269/ajtmh.14-0426 ER - TY - JOUR T1 - Discovery and Characterization of Potential Prognostic Biomarkers for Dengue Hemorrhagic Fever AN - 1727675165; PQ0002140054 AB - Half a million patients are hospitalized with severe dengue every year, many of whom would die without timely, appropriate clinical intervention. The majority of dengue cases are uncomplicated; however, 2-5% progress to severe dengue. Severe dengue cases have been reported with increasing frequency over the last 30 years. To discover biomarkers for severe dengue, we used surface-enhanced laser desorption/ionization time-of-flight mass spectrometry to analyze dengue virus positive serum samples from the acute phase of infection. Using this method, 16 proteins were identified as candidate biomarkers for severe dengue. From these 16 biomarkers, three candidates were selected for confirmation by enzyme-linked immunosorbent assay and Western blot: vitronectin (Vtn, 55.1 kDa), hemopexin (Hx, 52.4 kDa), and serotransferrin (Tf, 79.2 kDa). Vitronectin, Hx, and Tf best differentiated between dengue and severe dengue. JF - American Journal of Tropical Medicine and Hygiene AU - Poole-Smith, Katherine AU - Gilbert, Alexa AU - Gonzalez, Andrea L AU - Beltran, Manuela AU - Tomashek, Kay M AU - Ward, Brian J AU - Hunsperger, Elizabeth A AU - Ndao, Momar AD - Division of Vector-Borne Diseases, Dengue Branch, Centers for Disease Control and Prevention, San Juan, Puerto Rico, isd5@cdc.gov Y1 - 2014/12// PY - 2014 DA - December 2014 SP - 1218 EP - 1226 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 91 IS - 6 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Dengue virus KW - Western blotting KW - Enzyme-linked immunosorbent assay KW - Desorption KW - Biomarkers KW - Infection KW - biomarkers KW - Mass spectroscopy KW - Hemopexin KW - Dengue hemorrhagic fever KW - Dengue KW - Serum KW - vitronectin KW - Lasers KW - Hygiene KW - K 03400:Human Diseases KW - Q1 08484:Species interactions: parasites and diseases KW - J 02400:Human Diseases KW - Q5 08524:Public health, medicines, dangerous organisms KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727675165?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Discovery+and+Characterization+of+Potential+Prognostic+Biomarkers+for+Dengue+Hemorrhagic+Fever&rft.au=Poole-Smith%2C+Katherine%3BGilbert%2C+Alexa%3BGonzalez%2C+Andrea+L%3BBeltran%2C+Manuela%3BTomashek%2C+Kay+M%3BWard%2C+Brian+J%3BHunsperger%2C+Elizabeth+A%3BNdao%2C+Momar&rft.aulast=Poole-Smith&rft.aufirst=Katherine&rft.date=2014-12-01&rft.volume=91&rft.issue=6&rft.spage=1218&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0193 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Serum; Biomarkers; Hygiene; Hemopexin; Western blotting; Enzyme-linked immunosorbent assay; Dengue hemorrhagic fever; Desorption; Dengue; vitronectin; Lasers; Infection; biomarkers; Mass spectroscopy; Dengue virus DO - http://dx.doi.org/10.4269/ajtmh.14-0193 ER - TY - JOUR T1 - Parameters for Sample Size Estimation from a Group-Randomized HIV Prevention Trial in HIV Clinics in Sub-Saharan Africa AN - 1635026307; 20983561 AB - Sample size calculations for a group-randomized trial (GRT) require an estimate of the expected intraclass correlation coefficient (ICC). However, few ICC estimates from GRTs in HIV/AIDS research have been published, leaving investigators with little data on which to base expectations. We used data from a multi-country study to estimate ICCs for variables related to physical and mental health and HIV risk behaviors. ICCs for perceptions of physical and mental health tended to be higher than those for HIV risk behavior variables, which were higher than ICCs for CD4 count. Covariate adjustment for country and socio-demographic variables reduced most ICC estimates. For risk behavior variables, adjustment for country and socio-demographic variables reduced ICC estimates by as much as 84 %. Variability in ICC estimates has important implications for study design, as a larger ICC reduces power. ICC estimates presented in this analysis will allow more precise sample size estimates for future GRTs. JF - AIDS and Behavior AU - Zhang, Jun AU - Pals, Sherri L AU - Medley, Amy AU - Nichols, Catherine AU - Bachanas, Pam AU - Zyl, Deon AU - Katuta, Frieda AU - Juma, James AD - Division of Global HIV/AIDS, Center for Global Health, Centers for Disease Control and Prevention (CDC), 1600 Clifton Road, MS E-30, Atlanta, GA, 30333, USA, sfv3@cdc.gov Y1 - 2014/12// PY - 2014 DA - Dec 2014 SP - 2359 EP - 2365 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 18 IS - 12 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Risk Abstracts KW - Acquired immune deficiency syndrome KW - Data processing KW - Risk taking KW - Sexual behavior KW - Prevention KW - Mental disorders KW - CD4 antigen KW - Human immunodeficiency virus KW - Perception KW - Africa KW - V 22360:AIDS and HIV KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1635026307?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Parameters+for+Sample+Size+Estimation+from+a+Group-Randomized+HIV+Prevention+Trial+in+HIV+Clinics+in+Sub-Saharan+Africa&rft.au=Tatti%2C+K&rft.aulast=Tatti&rft.aufirst=K&rft.date=2011-05-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=111th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2011%29&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-12-01 N1 - Number of references - 27 N1 - Last updated - 2015-03-04 N1 - SubjectsTermNotLitGenreText - Acquired immune deficiency syndrome; CD4 antigen; Mental disorders; Data processing; Perception; Prevention; Human immunodeficiency virus; Risk taking; Sexual behavior; Africa DO - http://dx.doi.org/10.1007/s10461-013-0631-9 ER - TY - JOUR T1 - Federal environmental and occupational toxicology regulations and reporting requirements: a practical approach to what the medical toxicologist needs to know, part 2. AN - 1629965692; 25053379 AB - Toxicologists are often called upon to assist in environmental, industrial, occupational and public health assessments. Accordingly, medical toxicologists may find it prudent to be aware of applicable federal toxicological regulations and reporting requirements and of the roles of relevant federal agencies. These regulations are numerous, complex, and have evolved and expanded over time, making it difficult for toxicologists to sustain a current knowledge base. This article reviews the pertinent federal toxicological reporting requirements with regards to the Toxic Substances Control Act (TSCA), the Atomic Energy Act (AEA), the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), the Resource Conservation and Recovery Act (RCRA), the Clean Air Act, the Clean Water Act, the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), the Emergency Planning and Community Right to Know Act (EPCRA), the Occupational Safety and Health Act, the Department of Transportation, and information about the National Response Center. We reference internet-based government resources and offer direct links to applicable websites in an attempt to offer rapid and current sources of practical information. The format of the article is a series of hypothetical scenarios followed by commentary. Discussions of the Safe Drinking Water Act and the Food, Drug, and Cosmetic Act and the Dietary Supplement Health and Education Act are beyond the scope of this paper. For those desiring a more in depth discussion of the relevant federal environmental laws and statutes, and applicable case law, the reader is directed to resources such as the Environmental Law Handbook, the websites of individual laws found at www.epa.gov and the decisions of individual courts of appeal. It is our hope that this article provides not only useful practical information for the practicing toxicologist, but also serves as a key reference for Medical Toxicology core content on environmental laws and regulations. JF - Journal of medical toxicology : official journal of the American College of Medical Toxicology AU - Schwartz, Michael D AU - Dell'Aglio, Damon M AU - Nickle, Richard AU - Hornsby-Myers, Jennifer AD - Centers for Disease Control and Prevention/National Center for Environmental Health/Office of Environmental health Emergencies, 1600 Clifton Rd., MS F-09, Atlanta, GA, 30333, USA, aeo8@cdc.gov. Y1 - 2014/12// PY - 2014 DA - December 2014 SP - 415 EP - 427 VL - 10 IS - 4 KW - Index Medicus KW - United States KW - Humans KW - Occupational Health -- legislation & jurisprudence KW - United States Government Agencies -- legislation & jurisprudence KW - Ecotoxicology -- legislation & jurisprudence UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1629965692?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+medical+toxicology+%3A+official+journal+of+the+American+College+of+Medical+Toxicology&rft.atitle=Federal+environmental+and+occupational+toxicology+regulations+and+reporting+requirements%3A+a+practical+approach+to+what+the+medical+toxicologist+needs+to+know%2C+part+2.&rft.au=Schwartz%2C+Michael+D%3BDell%27Aglio%2C+Damon+M%3BNickle%2C+Richard%3BHornsby-Myers%2C+Jennifer&rft.aulast=Schwartz&rft.aufirst=Michael&rft.date=2014-12-01&rft.volume=10&rft.issue=4&rft.spage=415&rft.isbn=&rft.btitle=&rft.title=Journal+of+medical+toxicology+%3A+official+journal+of+the+American+College+of+Medical+Toxicology&rft.issn=1937-6995&rft_id=info:doi/10.1007%2Fs13181-014-0411-6 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2015-09-21 N1 - Date created - 2014-12-03 N1 - Date revised - 2017-01-14 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1007/s13181-014-0411-6 ER - TY - JOUR T1 - A case of abrin toxin poisoning, confirmed via quantitation of L-abrine (N-methyl-L-tryptophan) biomarker. AN - 1629965031; 24522983 AB - The seeds of Abrus precatorius contain the highly toxic plant protein abrin. There is no antidote for abrin poisoning. Management, largely supportive, may consist of administering intravenous fluids, anti-emetics, and activated charcoal depending on the time of exposure. We report the presentation of a single case of unintentional abrin poisoning confirmed by the quantitation of L-abrine biomarker. A previously healthy 22-month-old, 11.5-kg female presented to the hospital after ingesting approximately 20 rosary peas (A. precatorius) sold as a "peace bracelet". Her primary manifestations were episodes of forceful emesis that included food particles progressing to clear gastric fluid. The patient was tachycardic (HR = 134 bpm) but had brisk capillary refill and normal blood pressure (96/60 mmHg). Laboratory testing revealed elevated blood urea nitrogen (16 mg/dL) and serum creatinine (0.4 mg/dL). In the emergency department, the patient was resuscitated with 40 mL/kg normal saline via peripheral IV and received ondansetron (0.15 mg/kg IV) to control retching. The patient was discharged well 24 h after the ingestion. This is the first case of human abrin toxin poisoning confirmed by the quantitation of L-abrine as a biomarker. Quantifying the levels of abrin toxin in the body after exposure can help clinicians make informed decisions when managing patients with symptomatic exposures to seeds of A. precatorius. JF - Journal of medical toxicology : official journal of the American College of Medical Toxicology AU - Wooten, Joe Valentine AU - Pittman, Christopher T AU - Blake, Thomas A AU - Thomas, Jerry D AU - Devlin, John J AU - Higgerson, Renee A AU - Johnson, Rudolph C AD - National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA, jvw2@cdc.gov. Y1 - 2014/12// PY - 2014 DA - December 2014 SP - 392 EP - 394 VL - 10 IS - 4 KW - Biomarkers KW - 0 KW - Indole Alkaloids KW - Abrin KW - 1393-62-0 KW - abrine KW - P57TWL22IX KW - Index Medicus KW - Infant KW - Humans KW - Female KW - Indole Alkaloids -- analysis KW - Abrin -- poisoning UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1629965031?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+medical+toxicology+%3A+official+journal+of+the+American+College+of+Medical+Toxicology&rft.atitle=A+case+of+abrin+toxin+poisoning%2C+confirmed+via+quantitation+of+L-abrine+%28N-methyl-L-tryptophan%29+biomarker.&rft.au=Wooten%2C+Joe+Valentine%3BPittman%2C+Christopher+T%3BBlake%2C+Thomas+A%3BThomas%2C+Jerry+D%3BDevlin%2C+John+J%3BHiggerson%2C+Renee+A%3BJohnson%2C+Rudolph+C&rft.aulast=Wooten&rft.aufirst=Joe&rft.date=2014-12-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2015-09-21 N1 - Date created - 2014-12-03 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Cited By: Toxicol Rev. 2003;22(3):137-42 [15181663] J Biol Chem. 1974 Jun 10;249(11):3557-62 [4208663] J Toxicol Environ Health. 1981 Sep;8(3):409-17 [7345165] J Food Prot. 2012 Jan;75(1):112-7 [22221362] J Agric Food Chem. 2011 Sep 28;59(18):9796-9 [21870856] Toxins (Basel). 2011 Nov;3(11):1405-19 [22174977] J Anal Toxicol. 2009 Mar;33(2):77-84 [19239732] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1007/s13181-013-0377-9 ER - TY - JOUR T1 - Low Prospects and High Risk: Structural Determinants of Health Associated with Sexual Risk Among Young African American Women Residing in Resource-Poor Communities in the South AN - 1627978336; 20926078 AB - African American women at increased risk of HIV/sexually transmitted infection (STI) may engage in risky sex as a coping mechanism for depressed economic conditions. This study examines the association between high-risk sexual behavior and structural determinants of sexual health among a sample of young African American women. 237 young African American women (16-19 years old) from economically disadvantaged neighborhoods in North Carolina were enrolled into a randomized trial testing the efficacy of an adapted HIV/STI prevention intervention. Logistic regression analyses predicted the likelihood that young women reporting lack of food at home, homelessness and low future prospects would also report sexual risk behaviors. Young women reporting a lack of food at home (22 %), homelessness (27 %), and low perceived education/employment prospects (19 %) had between 2.2 and 4.7 times the odds as those not reporting these risk factors of reporting multiple sex partners, risky sex partners including older men and partners involved in gangs, substance use prior to sex, and exchange sex. Self-reported structural determinants of sexual health were associated with myriad sexual risk behaviors. Diminished economic conditions among these young women may lead to sexual risk due to hopelessness, the need for survival or other factors. JF - American Journal of Community Psychology AU - Raiford, Jerris L AU - Herbst, Jeffrey H AU - Carry, Monique AU - Browne, Felicia A AU - Doherty, Irene AU - Wechsberg, Wendee M AD - Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Mailstop E-37, Atlanta, GA, 30333, USA, jraiford@cdc.gov Y1 - 2014/12// PY - 2014 DA - Dec 2014 SP - 243 EP - 250 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 54 IS - 3-4 SN - 0091-0562, 0091-0562 KW - Risk Abstracts KW - USA, North Carolina KW - Intervention KW - Survival KW - Sexual behavior KW - Homelessness KW - Prevention KW - Education KW - Infectious diseases KW - Perception KW - Human immunodeficiency virus KW - Risk factors KW - Females KW - Economic conditions KW - Sexually transmitted diseases KW - Ethnic groups KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1627978336?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Community+Psychology&rft.atitle=Low+Prospects+and+High+Risk%3A+Structural+Determinants+of+Health+Associated+with+Sexual+Risk+Among+Young+African+American+Women+Residing+in+Resource-Poor+Communities+in+the+South&rft.au=Raiford%2C+Jerris+L%3BHerbst%2C+Jeffrey+H%3BCarry%2C+Monique%3BBrowne%2C+Felicia+A%3BDoherty%2C+Irene%3BWechsberg%2C+Wendee+M&rft.aulast=Raiford&rft.aufirst=Jerris&rft.date=2014-12-01&rft.volume=54&rft.issue=3-4&rft.spage=243&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Community+Psychology&rft.issn=00910562&rft_id=info:doi/10.1007%2Fs10464-014-9668-9 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-11-01 N1 - Number of references - 58 N1 - Last updated - 2014-12-24 N1 - SubjectsTermNotLitGenreText - Survival; Intervention; Sexual behavior; Homelessness; Education; Prevention; Infectious diseases; Human immunodeficiency virus; Perception; Risk factors; Females; Economic conditions; Ethnic groups; Sexually transmitted diseases; USA, North Carolina DO - http://dx.doi.org/10.1007/s10464-014-9668-9 ER - TY - JOUR T1 - Cholera at the Crossroads: The Association Between Endemic Cholera and National Access to Improved Water Sources and Sanitation AN - 1722173492; PQ0002099267 AB - We evaluated World Health Organization (WHO) national water and sanitation coverage levels and the infant mortality rate as predictors of endemic cholera in the 5-year period following water and sanitation coverage estimates using logistic regression, receiver operator characteristic curves, and different definitions of endemicity. Each was a significant predictors of endemic cholera at P < 0.001. Using a value of 250 for annual cases reported in 3 of 5 years, a national water access level of 71% has 65% sensitivity and 65% specificity in predicting endemic cholera, a sanitation access level of 39% has 63% sensitivity and 62% specificity, and an infant mortality rate of 65/1,000 has 67% sensitivity and 69% specificity. Our findings reveal the tradeoff between sensitivity and specificity for these predictors of endemic cholera and highlight the substantial uncertainty in the data. More accurate global surveillance data will enable more precise characterization of the benefits of improved water and sanitation. JF - American Journal of Tropical Medicine and Hygiene AU - Nygren, Benjamin L AU - Blackstock, Anna J AU - Mintz, Eric D AD - Division of Foodborne, Waterborne and Environmental Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, bnygren@cdc.gov Y1 - 2014/11// PY - 2014 DA - November 2014 SP - 1023 EP - 1028 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 91 IS - 5 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts KW - Sensitivity KW - Mortality KW - Data processing KW - Pathogenic bacteria KW - Specificity KW - Organizations KW - Bacterial diseases KW - Surveillance and enforcement KW - Infant mortality KW - Endemic species KW - Sanitation KW - Endemism KW - Cholera KW - Hygiene KW - Mortality causes KW - Infants KW - K 03400:Human Diseases KW - H 12000:Epidemiology and Public Health KW - Q1 08604:Stock assessment and management KW - J 02400:Human Diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1722173492?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Cholera+at+the+Crossroads%3A+The+Association+Between+Endemic+Cholera+and+National+Access+to+Improved+Water+Sources+and+Sanitation&rft.au=Nygren%2C+Benjamin+L%3BBlackstock%2C+Anna+J%3BMintz%2C+Eric+D&rft.aulast=Nygren&rft.aufirst=Benjamin&rft.date=2014-11-01&rft.volume=91&rft.issue=5&rft.spage=1023&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0331 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Endemic species; Organizations; Endemism; Specificity; Pathogenic bacteria; Bacterial diseases; Surveillance and enforcement; Hygiene; Mortality causes; Mortality; Data processing; Sanitation; Cholera; Infants; Infant mortality; Sensitivity DO - http://dx.doi.org/10.4269/ajtmh.14-0331 ER - TY - JOUR T1 - Genetic Determinants of Differential Oral Infection Phenotypes of West Nile and St. Louis Encephalitis Viruses in Culex spp. Mosquitoes AN - 1722173415; PQ0002099273 AB - St. Louis encephalitis virus (SLEV) has shown greater susceptibility to oral infectivity than West Nile virus (WNV) in Culex mosquitoes. To identify the viral genetic elements that modulate these disparate phenotypes, structural chimeras (WNV-pre-membrane [prM] and envelope [E] proteins [prME]/SLEV.IC (infectious clone) and SLEV-prME/WNV.IC) were constructed in which two of the structural proteins, the prM and E, were interchanged between viruses. Oral dose-response assessment with the chimeric/parental WNV and SLEV was performed to characterize the infection phenotypes in Culex mosquitoes by artificial blood meals. The median infectious dose required to infect 50% of Cx. quinquefasciatus with WNV was indistinguishable from that of the SLEV-prME/WNV.IC chimeric virus. Similarly, SLEV and WNV-prME/SLEV.IC virus exhibited an indistinguishable oral dose-response relationship in Cx. quinquefasciatus. Infection rates for WNV.IC and SLEV-prME/WNV.IC were significantly lower than SLEV.IC and WNV-prME/SLEV.IC infection rates. These results indicated that WNV and SLEV oral infectivities are not mediated by genetic differences within the prM and E proteins. JF - American Journal of Tropical Medicine and Hygiene AU - Maharaj, Payal D AU - Bolling, Bethany C AU - Anishchenko, Michael AU - Reisen, William K AU - Brault, Aaron C AD - Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado, abrault@cdc.gov Y1 - 2014/11// PY - 2014 DA - November 2014 SP - 1066 EP - 1072 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 91 IS - 5 SN - 0002-9637, 0002-9637 KW - Genetics Abstracts; CSA Neurosciences Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Entomology Abstracts; Virology & AIDS Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Clones KW - Viruses KW - Pest control KW - Blood meals KW - Phenotypes KW - Encephalitis KW - Structural proteins KW - Public health KW - Culex KW - Chimeras KW - Infectivity KW - Envelopes KW - Viral diseases KW - Dose-response effects KW - Envelope protein KW - Oral infection KW - Hygiene KW - Aquatic insects KW - West Nile virus KW - J 02410:Animal Diseases KW - G 07880:Human Genetics KW - V 22410:Animal Diseases KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - Q1 08604:Stock assessment and management KW - N3 11027:Neurology & neuropathology KW - Q5 08524:Public health, medicines, dangerous organisms KW - K 03310:Genetics & Taxonomy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1722173415?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Genetic+Determinants+of+Differential+Oral+Infection+Phenotypes+of+West+Nile+and+St.+Louis+Encephalitis+Viruses+in+Culex+spp.+Mosquitoes&rft.au=Maharaj%2C+Payal+D%3BBolling%2C+Bethany+C%3BAnishchenko%2C+Michael%3BReisen%2C+William+K%3BBrault%2C+Aaron+C&rft.aulast=Maharaj&rft.aufirst=Payal&rft.date=2014-11-01&rft.volume=91&rft.issue=5&rft.spage=1066&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0289 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Clones; Viral diseases; Viruses; Pest control; Hygiene; Phenotypes; Aquatic insects; Public health; Chimeras; Infectivity; Envelopes; Dose-response effects; Envelope protein; Blood meals; Oral infection; Structural proteins; Encephalitis; Culex; West Nile virus DO - http://dx.doi.org/10.4269/ajtmh.14-0289 ER - TY - JOUR T1 - Soil-Transmitted Helminths in Pre-School-Aged and School-Aged Children in an Urban Slum: A Cross-Sectional Study of Prevalence, Distribution, and Associated Exposures AN - 1722172947; PQ0002099263 AB - Soil-transmitted helminths (STHs) are controlled by regular mass drug administration. Current practice targets school-age children (SAC) preferentially over pre-school age children (PSAC) and treats large areas as having uniform prevalence. We assessed infection prevalence in SAC and PSAC and spatial infection heterogeneity, using a cross-sectional study in two slum villages in Kibera, Nairobi. Nairobi has low reported STH prevalence. The SAC and PSAC were randomly selected from the International Emerging Infections Program's surveillance platform. Data included residence location and three stools tested by Kato-Katz for STHs. Prevalences among 692 analyzable children were any STH: PSAC 40.5%, SAC 40.7%; Ascaris: PSAC 24.1%, SAC 22.7%; Trichuris: PSAC 24.0%, SAC 28.8%; hookworm < 0.1%. The STH infection prevalence ranged from 22% to 71% between sub-village sectors. The PSAC have similar STH prevalences to SAC and should receive deworming. Small areas can contain heterogeneous prevalences; determinants of STH infection should be characterized and slums should be assessed separately in STH mapping. JF - American Journal of Tropical Medicine and Hygiene AU - Davis, Stephanie M AU - Worrell, Caitlin M AU - Wiegand, Ryan E AU - Odero, Kennedy O AU - Suchdev, Parminder S AU - Ruth, Laird J AU - Lopez, Gerard AU - Cosmas, Leonard AU - Neatherlin, John AU - Njenga, Sammy M AU - Montgomery, Joel M AU - Fox, LeAnne M AD - Parasitic Diseases Branch, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, Vic6@cdc.gov Y1 - 2014/11// PY - 2014 DA - November 2014 SP - 1002 EP - 1010 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 91 IS - 5 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Age KW - Data processing KW - Surveillance and enforcement KW - Kenya, Nairobi KW - Infection KW - Children KW - Ascaris KW - Mapping KW - Feces KW - Hygiene KW - Drugs KW - K 03400:Human Diseases KW - J 02400:Human Diseases KW - Q1 08604:Stock assessment and management KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1722172947?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Soil-Transmitted+Helminths+in+Pre-School-Aged+and+School-Aged+Children+in+an+Urban+Slum%3A+A+Cross-Sectional+Study+of+Prevalence%2C+Distribution%2C+and+Associated+Exposures&rft.au=Davis%2C+Stephanie+M%3BWorrell%2C+Caitlin+M%3BWiegand%2C+Ryan+E%3BOdero%2C+Kennedy+O%3BSuchdev%2C+Parminder+S%3BRuth%2C+Laird+J%3BLopez%2C+Gerard%3BCosmas%2C+Leonard%3BNeatherlin%2C+John%3BNjenga%2C+Sammy+M%3BMontgomery%2C+Joel+M%3BFox%2C+LeAnne+M&rft.aulast=Davis&rft.aufirst=Stephanie&rft.date=2014-11-01&rft.volume=91&rft.issue=5&rft.spage=1002&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0060 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Surveillance and enforcement; Hygiene; Drugs; Age; Data processing; Mapping; Feces; Children; Infection; Ascaris; Kenya, Nairobi DO - http://dx.doi.org/10.4269/ajtmh.14-0060 ER - TY - JOUR T1 - The Effect of a Health Communication Campaign on Compliance with Mass Drug Administration for Schistosomiasis Control in Western Kenya-The SCORE Project AN - 1722166559; PQ0002099259 AB - Compliance with mass drug administration (MDA) can be affected by rumors and mistrust about the drug. Communication campaigns are an effective way to influence attitudes and health behaviors in diverse public health contexts, but there is very little documentation about experiences using health communications in schistosomiasis control programs. A qualitative study was conducted with community health workers (CHWs) as informants to explore the effect of a health communication campaign on their experiences during subsequent praziquantel MDA for schistosomiasis. Discussions were audio-recorded, transcribed verbatim, translated into English where applicable, and analyzed thematically using ATLAS.ti software. According to the CHWs, exposure to mass media messages improved awareness of the MDA, which in turn, led to better treatment compliance. Our findings suggest that communication campaigns influence health behaviors and create awareness of schistosomiasis control interventions, which may ultimately improve praziquantel MDA. JF - American Journal of Tropical Medicine and Hygiene AU - Omedo, Martin AU - Ogutu, Michael AU - Awiti, Alphonce AU - Musuva, Rosemary AU - Muchiri, Geoffrey AU - Montgomery, Susan P AU - Secor, W Evan AU - Mwinzi, Pauline AD - Neglected Tropical Diseases Branch, Center for Global Health Research, Kenya Medical Research Institute (KEMRI), Kisumu, Kenya, was4@cdc.gov Y1 - 2014/11// PY - 2014 DA - November 2014 SP - 982 EP - 988 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 91 IS - 5 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts KW - Compliance KW - Communication KW - Intervention KW - Public health KW - Computer programs KW - Workers KW - Attitudes KW - software KW - Schistosoma KW - Praziquantel KW - Drugs KW - Occupational exposure KW - Control programs KW - Schistosomiasis KW - Communications KW - Behavior KW - Hygiene KW - Mass media KW - K 03450:Ecology KW - J 02400:Human Diseases KW - H 1000:Occupational Safety and Health KW - Q1 08485:Species interactions: pests and control KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1722166559?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=8th+ASM+Biodefense+and+Emerging+Diseases+Research+Meeting&rft.atitle=Survival+and+Persistence+of+Non-Spore+Forming+Biothreat+Agents+in+Water&rft.au=Gilbert%2C+S+E%3BRose%2C+L+J%3BNoble-Wang%2C+J&rft.aulast=Gilbert&rft.aufirst=S&rft.date=2010-02-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=8th+ASM+Biodefense+and+Emerging+Diseases+Research+Meeting&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Schistosomiasis; Hygiene; Drugs; Public health; Workers; Computer programs; software; Control programs; Communication; Praziquantel; Attitudes; Communications; Behavior; Compliance; Intervention; Occupational exposure; Mass media; Schistosoma DO - http://dx.doi.org/10.4269/ajtmh.14-0136 ER - TY - JOUR T1 - Effectiveness of Oral Polio Vaccination Against Paralytic Poliomyelitis: A Matched Case-Control Study in Somalia AN - 1687692120; PQ0001574028 AB - Background. After the last case of type 1 wild poliovirus (WPV1) was reported in 2007, Somalia experienced another outbreak of WPV1 (189 cases) in 2013. Methods. We conducted a retrospective, matched case-control study to evaluate the vaccine effectiveness (VE) of oral polio vaccine (OPV). We retrieved information from the Somalia Surveillance Database. A case was defined as any case of acute flaccid paralysis (AFP) with virological confirmation of WPV1. We selected two groups of controls for each case: non-polio AFP cases ("NPAFP controls") matched to WPV1 cases by age, date of onset of paralysis and region; and asymptomatic "neighborhood controls," matched by age. Using conditional logistic regression, we estimated the VE of OPV as (1 - odds ratio) x 100. Result. We matched 99 WPV cases with 99 NPAFP controls and 134 WPV1 cases with 268 neighborhood controls. Using NPAFP controls, the overall VE was 70% (95% confidence interval [CI], 37-86), 59% (2-83) among 1-3 dose recipients, 77% (95% CI, 46-91) among > or =4 dose recipients. In neighborhood controls, the overall VE was 95% (95% CI, 84-98), 92% (72-98) among 1-3 dose recipients, and 97% (89-99) among > or =4 dose recipients. When the analysis was limited to cases and controls < or =24 months old, the overall VE in NPAFP and neighborhood controls was 95% (95% CI, 65-99) and 97% (95% CI, 76-100), respectively. Conclusions. Among individuals who were fully vaccinated with OPV, vaccination was effective at preventing WPV1 in Somalia. JF - Journal of Infectious Diseases AU - Mahamud, Abdirahman AU - Kamadjeu, Raoul AU - Webeck, Jenna AU - Mbaeyi, Chukwuma AU - Baranyikwa, Marie Therese AU - Birungi, Julianne AU - Nurbile, Yassin AU - Ehrhardt, Derek AU - Shukla, Hemant AU - Chatterjee, Anirban AU - Mulugeta, Abraham AD - Centers for Disease Control and Prevention, 1600 Clifton Rd NE Mailstop A-04, Atlanta, GA 30333, amahamud@cdc.gov Y1 - 2014/11/01/ PY - 2014 DA - 2014 Nov 01 SP - S187 EP - S193 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 210 SN - 0022-1899, 0022-1899 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - vaccine effectiveness KW - oral polio vaccine KW - Somalia KW - Paralysis KW - Databases KW - Age KW - Poliovirus KW - Infectious diseases KW - Poliomyelitis KW - Outbreaks KW - Vaccines KW - Vaccination KW - V 22490:Miscellaneous KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1687692120?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Effectiveness+of+Oral+Polio+Vaccination+Against+Paralytic+Poliomyelitis%3A+A+Matched+Case-Control+Study+in+Somalia&rft.au=Mahamud%2C+Abdirahman%3BKamadjeu%2C+Raoul%3BWebeck%2C+Jenna%3BMbaeyi%2C+Chukwuma%3BBaranyikwa%2C+Marie+Therese%3BBirungi%2C+Julianne%3BNurbile%2C+Yassin%3BEhrhardt%2C+Derek%3BShukla%2C+Hemant%3BChatterjee%2C+Anirban%3BMulugeta%2C+Abraham&rft.aulast=Mahamud&rft.aufirst=Abdirahman&rft.date=2014-11-01&rft.volume=210&rft.issue=&rft.spage=S187&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiu261 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-06-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Paralysis; Databases; Poliomyelitis; Vaccines; Vaccination; Poliovirus; Age; Infectious diseases; Outbreaks; Somalia DO - http://dx.doi.org/10.1093/infdis/jiu261 ER - TY - JOUR T1 - Progress and Peril: Poliomyelitis Eradication Efforts in Pakistan, 1994-2013 AN - 1687688388; PQ0001574024 AB - Pakistan is one of 3 countries where transmission of indigenous wild poliovirus (WPV) has never been interrupted. Numbers of confirmed polio cases have declined by >90% from preeradication levels, although outbreaks occurred during 2008-2013. During 2012 and 2013, 58 and 93 WPV cases, respectively, were reported, almost all of which were due to WPV type 1. Of the 1 51 WPV cases reported during 2012-2013, 123 (81%) occurred in the conflict-affected Federally Administered Tribal Areas (FATA) and in security-compromised Khyber Pakhtunkhwa province. WPV type 3 was isolated from only 3 persons with polio in a single district in 2012. During August 2012-December 2013, 62 circulating vaccine-derived poliovirus type 2 cases were detected, including 40 cases (65%) identified in the FATA during 2013. Approximately 350 000 children in certain districts of the FATA have not received polio vaccine during supplementary immunization activities (SIAs) conducted since mid-2012, because local authorities have banned polio vaccination. In other areas of Pakistan, SIAs have been compromised by attacks targeting polio workers, which started in mid-2012. Further efforts to reach children in conflict-affected and security-compromised areas will be necessary to prevent reintroduction of WPV into other areas of Pakistan and other parts of the world. JF - Journal of Infectious Diseases AU - Alexander, James P, Jr AU - Zubair, Mufti AU - Khan, Muzaffar AU - Abid, Nima AU - Durry, Elias AD - Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Mailstop A-04, Atlanta, GA 30333, axj1@cdc.gov Y1 - 2014/11/01/ PY - 2014 DA - 2014 Nov 01 SP - S152 EP - S161 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 210 SN - 0022-1899, 0022-1899 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - polio KW - disease eradication KW - epidemiology KW - surveillance KW - Pakistan KW - Reintroduction KW - Poliovirus KW - Children KW - Vaccination KW - Immunization KW - Disease transmission KW - Local authority KW - Workers KW - Infectious diseases KW - Poliomyelitis KW - Outbreaks KW - Vaccines KW - H 1000:Occupational Safety and Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1687688388?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Progress+and+Peril%3A+Poliomyelitis+Eradication+Efforts+in+Pakistan%2C+1994-2013&rft.au=Alexander%2C+James+P%2C+Jr%3BZubair%2C+Mufti%3BKhan%2C+Muzaffar%3BAbid%2C+Nima%3BDurry%2C+Elias&rft.aulast=Alexander&rft.aufirst=James&rft.date=2014-11-01&rft.volume=210&rft.issue=&rft.spage=S152&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiu450 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-06-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Reintroduction; Workers; Poliomyelitis; Vaccines; Children; Vaccination; Disease transmission; Local authority; Poliovirus; Infectious diseases; Outbreaks; Immunization; Pakistan DO - http://dx.doi.org/10.1093/infdis/jiu450 ER - TY - JOUR T1 - An Evaluation of Polio Supplemental Immunization Activities in Kano, Katsina, and Zamfara States, Nigeria: Lessons in Progress AN - 1687688255; PQ0001574018 AB - Background. As 1 of 3 remaining poliovirus-endemic countries, Nigeria has become key to the global polio eradication effort. We evaluated supplemental immunization activities, including team performance, communications/mobilization activities, and vaccine acceptance, in 3 high-risk states. Methods. We used structured survey and observation instruments, document review, and stakeholder interviews. Results. Observations or surveys were conducted at 1697 households. Vaccine acceptance ranged from 87%-94%; among households rejecting polio vaccine, 38% of mothers sought measles vaccine for their children. Teams performed between 4%-42% of assigned tasks. Conclusions. Acceptance is high but teams have a critical role in surmounting residual vaccine resistance. JF - Journal of Infectious Diseases AU - Gammino, Victoria M AU - Nuhu, Adamu AU - Gerber, Sue AU - Gasasira, Alex AU - Sugerman, David E AU - Manneh, Fadinding AU - Chenoweth, Paul AU - Kurnit, Molly R AU - Abanida, Emmanuel A AD - Global Immunization Division, US Centers for Disease Control and Prevention, 1600 Clifton Rd, MS A-04, Atlanta, GA 30329, vmg0@cdc.gov Y1 - 2014/11/01/ PY - 2014 DA - 2014 Nov 01 SP - S91 EP - S97 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 210 SN - 0022-1899, 0022-1899 KW - Risk Abstracts; Health & Safety Science Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - eradication KW - evaluation KW - immunization KW - microplanning KW - Nigeria KW - outbreak KW - polio KW - social mobilization KW - structured observation KW - survey KW - Stakeholders KW - Poliovirus KW - Measles KW - Communication KW - Children KW - Immunization KW - Communications KW - Infectious diseases KW - Households KW - Reviews KW - Risk groups KW - Vaccines KW - R2 23060:Medical and environmental health KW - F 06910:Microorganisms & Parasites KW - H 4000:Food and Drugs KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1687688255?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=An+Evaluation+of+Polio+Supplemental+Immunization+Activities+in+Kano%2C+Katsina%2C+and+Zamfara+States%2C+Nigeria%3A+Lessons+in+Progress&rft.au=Gammino%2C+Victoria+M%3BNuhu%2C+Adamu%3BGerber%2C+Sue%3BGasasira%2C+Alex%3BSugerman%2C+David+E%3BManneh%2C+Fadinding%3BChenoweth%2C+Paul%3BKurnit%2C+Molly+R%3BAbanida%2C+Emmanuel+A&rft.aulast=Gammino&rft.aufirst=Victoria&rft.date=2014-11-01&rft.volume=210&rft.issue=&rft.spage=S91&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiu228 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-06-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Measles; Reviews; Communication; Risk groups; Vaccines; Children; Immunization; Stakeholders; Poliovirus; Communications; Infectious diseases; Households; Nigeria DO - http://dx.doi.org/10.1093/infdis/jiu228 ER - TY - JOUR T1 - Polio Eradication Initiative in Afghanistan, 1997-2013 AN - 1687687510; PQ0001574025 AB - Background. This article reviews the epidemiology of polio, acute flaccid paralysis (AFP) surveillance, and the implementation of supplemental immunization activities (SIAs) in Afghanistan from 1997 thru 2013. Methods. Published reports and unpublished national data on polio cases, AFP surveillance, and SIAs were analyzed. Recommendations from independent advisory groups and Afghan government informed the conclusions. Results. From 1997 thru 2013, the annual number of confirmed polio cases fluctuated from a low of 4 in 2004 to a high of 80 in 2011. Wild poliovirus types 2 and 3 were last reported in 1997 and 2010, respectively. Circulating vaccine-derived poliovirus type 2 emerged in 2009. AFP surveillance quality in children aged 8 per 100 000 population. Since 2001, at least 6 SIAs have been conducted annually. Conclusions. Afghanistan has made progress moving closer to eliminating polio. The program struggles to reach all children because of management and accountability problems in the field, inaccessible populations, and inadequate social mobilization. Consequently, too many children are missed during SIAs. Afghanistan adopted a national emergency action plan in 2012 to address these issues, but national elimination will require consistent and complete implementation of proven strategies. JF - Journal of Infectious Diseases AU - Simpson, Diane M AU - Sadr-Azodi, Nahad AU - Mashal, Taufiq AU - Sabawoon, Wrishmeen AU - Pardis, Ajmal AU - Quddus, Arshad AU - Garrigos, Carmen AU - Guirguis, Sherine AU - Zaidi, Syed Sohail Zahoor AU - Shaukat, Shahzad AU - Sharif, Salmaan AU - Asghar, Humayan AU - Hadler, Stephen C AD - Centers for Disease Control and Prevention, Center for Global Health, Global Immunization Division, 1600 Clifton Rd NE, Atlanta, GA 30333, dms3@cdc.gov Y1 - 2014/11/01/ PY - 2014 DA - 2014 Nov 01 SP - S162 EP - S172 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 210 SN - 0022-1899, 0022-1899 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - polio KW - disease eradication KW - Afghanistan KW - epidemiology KW - strategies KW - Poliovirus KW - Data processing KW - Accountability KW - Children KW - Immunization KW - Paralysis KW - Infectious diseases KW - Epidemiology KW - Reviews KW - Vaccines KW - H 4000:Food and Drugs KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1687687510?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Polio+Eradication+Initiative+in+Afghanistan%2C+1997-2013&rft.au=Simpson%2C+Diane+M%3BSadr-Azodi%2C+Nahad%3BMashal%2C+Taufiq%3BSabawoon%2C+Wrishmeen%3BPardis%2C+Ajmal%3BQuddus%2C+Arshad%3BGarrigos%2C+Carmen%3BGuirguis%2C+Sherine%3BZaidi%2C+Syed+Sohail+Zahoor%3BShaukat%2C+Shahzad%3BSharif%2C+Salmaan%3BAsghar%2C+Humayan%3BHadler%2C+Stephen+C&rft.aulast=Simpson&rft.aufirst=Diane&rft.date=2014-11-01&rft.volume=210&rft.issue=&rft.spage=S162&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiu022 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-06-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Paralysis; Data processing; Epidemiology; Children; Immunization; Poliovirus; Infectious diseases; Reviews; Vaccines; Accountability; Afghanistan DO - http://dx.doi.org/10.1093/infdis/jiu022 ER - TY - JOUR T1 - Challenges of Maintaining Polio-free Status of the European Region AN - 1687687413; PQ0001574029 AB - Background. The European region, certified as polio free in 2002, had recent wild poliovirus (WPV) introductions, resulting in a major outbreak in Central Asian countries and Russia in 2010 and in current widespread WPV type 1 circulation in Israel, which endangered the polio-free status of the region. Methods. We assessed the data on the major determinants of poliovirus transmission risk (population immunity, surveillance, and outbreak preparedness) and reviewed current threats and measures implemented in response to recent WPV introductions. Results. Despite high regional vaccination coverage and functioning surveillance, several countries in the region are at high or intermediate risk of poliovirus transmission. Coverage remains suboptimal in some countries, subnational geographic areas, and population groups, and surveillance (acute flaccid paralysis, enterovirus, and environmental) needs further strengthening. Supplementary immunization activities, which were instrumental in the rapid interruption of WPV1 circulation in 2010, should be implemented in high-risk countries to close population immunity gaps. National polio outbreak preparedness plans need strengthening. Immunization efforts to interrupt WPV transmission in Israel should continue. Conclusions. The European region has successfully maintained its polio-free status since 2002, but numerous challenges remain. Staying polio free will require continued coordinated efforts, political commitment and financial support from all countries. JF - Journal of Infectious Diseases AU - Khetsuriani, Nino AU - Pfeifer, Dina AU - Deshevoi, Sergei AU - Gavrilin, Eugene AU - Shefer, Abigail AU - Butler, Robb AU - Jankovic, Dragan AU - Spataru, Roman AU - Emiroglu, Nedret AU - Martin, Rebecca AD - Centers for Disease Control and Prevention, Atlanta, Georgia; European Region, Global Immunization Division, Center for Global Health, CDC, 1600 Clifton Rd. Atlanta, GA 30333, USA, nck7@cdc.gov Y1 - 2014/11/01/ PY - 2014 DA - 2014 Nov 01 SP - S194 EP - S207 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 210 SN - 0022-1899, 0022-1899 KW - Risk Abstracts; Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - poliomyelitis KW - polio eradication KW - European region KW - polio-free status KW - Risk assessment KW - Poliovirus KW - Data processing KW - Politics KW - Israel KW - Immunity KW - Vaccination KW - Immunization KW - Disease transmission KW - Paralysis KW - Enterovirus KW - Infectious diseases KW - INW, Russia KW - Risk factors KW - Reviews KW - Risk groups KW - Outbreaks KW - Vaccines KW - V 22350:Immunology KW - R2 23060:Medical and environmental health KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1687687413?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Challenges+of+Maintaining+Polio-free+Status+of+the+European+Region&rft.au=Khetsuriani%2C+Nino%3BPfeifer%2C+Dina%3BDeshevoi%2C+Sergei%3BGavrilin%2C+Eugene%3BShefer%2C+Abigail%3BButler%2C+Robb%3BJankovic%2C+Dragan%3BSpataru%2C+Roman%3BEmiroglu%2C+Nedret%3BMartin%2C+Rebecca&rft.aulast=Khetsuriani&rft.aufirst=Nino&rft.date=2014-11-01&rft.volume=210&rft.issue=&rft.spage=S194&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiu096 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-06-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Paralysis; Data processing; Reviews; Risk factors; Risk groups; Immunity; Vaccination; Disease transmission; Risk assessment; Poliovirus; Infectious diseases; Politics; Vaccines; Outbreaks; Immunization; Enterovirus; INW, Russia; Israel DO - http://dx.doi.org/10.1093/infdis/jiu096 ER - TY - JOUR T1 - Forewarning of Poliovirus Outbreaks in the Horn of Africa: An Assessment of Acute Flaccid Paralysis Surveillance and Routine Immunization Systems in Kenya AN - 1687681951; PQ0001574017 AB - Background. Although the Horn of Africa region has successfully eliminated endemic poliovirus circulation, it remains at risk for reintroduction. International partners assisted Kenya in identifying gaps in the polio surveillance and routine immunization programs, and provided recommendations for improved surveillance and routine immunization during the health system decentralization process. Methods. Structured questionnaires collected information about acute flaccid paralysis (AFP) surveillance resources, training, data monitoring, and supervision at provincial, district, and health facility levels. The routine immunization program information collected included questions about vaccine and resource availability, cold chain, logistics, health-care services and access, outreach coverage data, microplanning, and management and monitoring of AFP surveillance. Results. Although AFP surveillance met national performance standards, widespread deficiencies and limited resources were observed and reported at all levels. Deficiencies were related to provider knowledge, funding, training, and supervision, and were particularly evident at the health facility level. Conclusions. Gap analysis assists in maximizing resources and capacity building in countries where surveillance and routine immunization lag behind other health priorities. Limited resources for surveillance and routine immunization systems in the region indicate a risk for additional outbreaks of wild poliovirus and other vaccine-preventable illnesses. Monitoring and evaluation of program strengthening activities are needed. JF - Journal of Infectious Diseases AU - Walker, Allison Taylor AU - Sodha, Samir AU - Warren, Wick C AU - Sergon, Kibet AU - Kiptoon, Shem AU - Ogange, John AU - Ahmeda, Abdi Hassan AU - Eshetu, Messeret AU - Corkum, Melissa AU - Pillai, Satish AD - Centers for Disease Control and Prevention, 1600 Clifton Rd, MS-A38, Atlanta, GA 30333, ATWalker@cdc.gov Y1 - 2014/11/01/ PY - 2014 DA - 2014 Nov 01 SP - S85 EP - S90 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 210 SN - 0022-1899, 0022-1899 KW - Risk Abstracts; Health & Safety Science Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - decentralization KW - polio KW - program review KW - routine immunization KW - surveillance KW - Risk assessment KW - Reintroduction KW - Inventories KW - Poliovirus KW - Data processing KW - Training KW - Resource availability KW - Carrying capacity KW - Immunization KW - Horns KW - Paralysis KW - Kenya KW - Infectious diseases KW - Africa KW - Priorities KW - Outbreaks KW - Vaccines KW - Gap analysis KW - V 22490:Miscellaneous KW - R2 23060:Medical and environmental health KW - F 06910:Microorganisms & Parasites KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1687681951?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Forewarning+of+Poliovirus+Outbreaks+in+the+Horn+of+Africa%3A+An+Assessment+of+Acute+Flaccid+Paralysis+Surveillance+and+Routine+Immunization+Systems+in+Kenya&rft.au=Walker%2C+Allison+Taylor%3BSodha%2C+Samir%3BWarren%2C+Wick+C%3BSergon%2C+Kibet%3BKiptoon%2C+Shem%3BOgange%2C+John%3BAhmeda%2C+Abdi+Hassan%3BEshetu%2C+Messeret%3BCorkum%2C+Melissa%3BPillai%2C+Satish&rft.aulast=Walker&rft.aufirst=Allison&rft.date=2014-11-01&rft.volume=210&rft.issue=&rft.spage=S85&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiu149 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-06-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Reintroduction; Paralysis; Horns; Inventories; Data processing; Vaccines; Gap analysis; Immunization; Risk assessment; Poliovirus; Infectious diseases; Training; Carrying capacity; Resource availability; Priorities; Outbreaks; Kenya; Africa DO - http://dx.doi.org/10.1093/infdis/jiu149 ER - TY - JOUR T1 - Polio Eradication in the World Health Organization African Region, 2008-2012 AN - 1687680443; PQ0001574012 AB - A renewed commitment at the regional and the global levels led to substantial progress in the fight for polio eradication in the African Region (AFR) of the World Health Organization (WHO) during 2008-2012. In 2008, there were 912 reported cases of wild poliovirus (WPV) infection in 12 countries in the region. This number had been reduced to 128 cases in 3 countries in 2012, of which 122 were in Nigeria, the only remaining country with endemic circulation of WPV in AFR. During 2008-2012, circulation apparently ceased in the 3 AFR countries with reestablished WPV transmission-Angola, the Democratic Republic of the Congo, and Chad. Outbreaks in West Africa continued to occur in 2008-2010 but were more rapidly contained, with fewer cases than during earlier years. This progress has been attributed to better implementation of core strategies, increased accountability, and implementation of innovative approaches. During this period, routine coverage with 3 doses of oral polio vaccine in AFR, as measured by WHO-United Nations Children's Fund estimates, increased slightly, from 72% to 74%. Despite this progress, challenges persist in AFR, and 2013 was marked by new setbacks and importations. High population immunity and strong surveillance are essential to sustain progress and assure that AFR reaches its goal of eradicating WPV. JF - Journal of Infectious Diseases AU - Kretsinger, Katrina AU - Gasasira, Alex AU - Poy, Alain AU - Porter, Kimberly A AU - Everts, Johannes AU - Salla, Mbaye AU - Brown, Kristin H AU - Wassilak, Steven G F AU - Nshimirimana, Deogratias AD - Global Immunization Division, Centers for Disease Control and Prevention, 1600 Clifton Rd, NE, MS A-04, Atlanta, GA 30333, kok4@cdc.gov Y1 - 2014/11/01/ PY - 2014 DA - 2014 Nov 01 SP - S23 EP - S39 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 210 SN - 0022-1899, 0022-1899 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - polio eradication KW - wild poliovirus KW - WHO Africa Region KW - Africa KW - vaccine-derived poliovirus KW - acute flaccid paralysis KW - surveillance KW - Nigeria KW - Funds KW - Poliovirus KW - Immunity KW - Accountability KW - Infection KW - Children KW - Importation KW - Infectious diseases KW - Chad KW - Outbreaks KW - Vaccines KW - Innovations KW - H 4000:Food and Drugs KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1687680443?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Polio+Eradication+in+the+World+Health+Organization+African+Region%2C+2008-2012&rft.au=Kretsinger%2C+Katrina%3BGasasira%2C+Alex%3BPoy%2C+Alain%3BPorter%2C+Kimberly+A%3BEverts%2C+Johannes%3BSalla%2C+Mbaye%3BBrown%2C+Kristin+H%3BWassilak%2C+Steven+G+F%3BNshimirimana%2C+Deogratias&rft.aulast=Kretsinger&rft.aufirst=Katrina&rft.date=2014-11-01&rft.volume=210&rft.issue=&rft.spage=S23&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-06-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Vaccines; Immunity; Importation; Children; Infection; Poliovirus; Funds; Infectious diseases; Outbreaks; Accountability; Innovations; Nigeria; Chad; Africa DO - http://dx.doi.org/10.1093/infdis/jiu408 ER - TY - JOUR T1 - Factors Contributing to Outbreaks of Wild Poliovirus Type 1 Infection Involving Persons Aged > or =15 Years in the Democratic Republic of the Congo, 2010-2011, Informed by a Pre-Outbreak Poliovirus Immunity Assessment AN - 1687680355; PQ0001574015 AB - Background. The Democratic Republic of the Congo (DRC) experienced atypical outbreaks of wild poliovirus type 1 (WPV1) infection during 2010-2011 in that they affected persons aged > or =15 years in 4 (Bandundu, Bas Congo, Kasai Occidental, and Kinshasa provinces) of the 6 provinces with outbreaks. Methods. Analyses of cases of WPV1 infection with onset during 2010-2011 by province, age, polio vaccination status, and sex were conducted. The prevalence of antibodies to poliovirus (PV) types 1, 2, and 3 was assessed in sera collected before the outbreaks from women attending antenatal clinics in 3 of the 4 above-mentioned provinces. Results. Of 193 cases of WPV1 infection during 2010-2011, 32 (17%) occurred in individuals aged > or =15 years. Of these 32 cases, 31 (97%) occurred in individuals aged 16-29 years; 9 (28%) were notified in Bandundu, 17 (53%) were notified in Kinshasa, and 22 (69%) had an unknown polio vaccination status. In the seroprevalence assessment, PV type 1 and 3 seroprevalence was lower among women aged 15-29 years in Bandundu and Kinshasa, compared with those in Kasai Occidental. Seropositivity to PVs was associated with increasing age, more pregnancies, and a younger age at first pregnancy. Conclusions. This spatiotemporal analysis strongly suggests that the 2010-2011 outbreaks of WPV1 infection affecting young adults were caused by a PV type 1 immunity gap in Kinshasa and Bandundu due to insufficient exposure to PV type 1 through natural infection or vaccination. Poliovirus immunity gaps in this age group likely persist in DRC. JF - Journal of Infectious Diseases AU - Alleman, Mary M AU - Wannemuehler, Kathleen A AU - Weldon, William C AU - Kabuayi, Jean Pierre AU - Ekofo, Felly AU - Edidi, Samuel AU - Mulumba, Audry AU - Mbule, Albert AU - Ntumbannji, Renee N AU - Coulibaly, Tiekoura AU - Abiola, Nadine AU - Mpingulu, Minlangu AU - Sidibe, Kassim AU - Oberste, M Steven AD - Global Immunization Division, Centers for Disease Control and Prevention, 1600 Clifton Rd, NE, MSA-04, Atlanta, GA 30333, mea4@cdc.gov Y1 - 2014/11/01/ PY - 2014 DA - 2014 Nov 01 SP - S62 EP - S73 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 210 SN - 0022-1899, 0022-1899 KW - Health & Safety Science Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - polio eradication KW - polio seroprevalence KW - neutralizing antibodies KW - Democratic Republic of the Congo KW - Africa KW - wild poliovirus outbreaks KW - polio in adults KW - Poliovirus KW - Age KW - Immunity KW - Infection KW - Vaccination KW - Pregnancy KW - Antibodies KW - Infectious diseases KW - Age groups KW - Outbreaks KW - Vaccines KW - Young adults KW - Sex KW - F 06910:Microorganisms & Parasites KW - H 0500:General KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1687680355?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Factors+Contributing+to+Outbreaks+of+Wild+Poliovirus+Type+1+Infection+Involving+Persons+Aged+%26gt%3B+or+%3D15+Years+in+the+Democratic+Republic+of+the+Congo%2C+2010-2011%2C+Informed+by+a+Pre-Outbreak+Poliovirus+Immunity+Assessment&rft.au=Alleman%2C+Mary+M%3BWannemuehler%2C+Kathleen+A%3BWeldon%2C+William+C%3BKabuayi%2C+Jean+Pierre%3BEkofo%2C+Felly%3BEdidi%2C+Samuel%3BMulumba%2C+Audry%3BMbule%2C+Albert%3BNtumbannji%2C+Renee+N%3BCoulibaly%2C+Tiekoura%3BAbiola%2C+Nadine%3BMpingulu%2C+Minlangu%3BSidibe%2C+Kassim%3BOberste%2C+M+Steven&rft.aulast=Alleman&rft.aufirst=Mary&rft.date=2014-11-01&rft.volume=210&rft.issue=&rft.spage=S62&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiu282 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-06-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Antibodies; Age; Immunity; Infection; Vaccination; Sex; Pregnancy; Poliovirus; Infectious diseases; Age groups; Young adults; Vaccines; Outbreaks DO - http://dx.doi.org/10.1093/infdis/jiu282 ER - TY - JOUR T1 - Polio Outbreak Among Nomads in Chad: Outbreak Response and Lessons Learned AN - 1687680142; PQ0001574016 AB - Background. In response to the 2011 and 2012 polio epidemic in Chad, Chad's Ministry of Public Health, with support from Global Polio Eradication Initiative partners, took steps to increase vaccination coverage of nomadic children with targeted polio campaigns. This article describes the strategies we used to vaccinate nomads in 3 districts of Chad. Methods. Our targeted interventions involved using mobile vaccination teams, recruiting local nomads to identify settlements, using social mobilization, and offering vaccinations to children, women, and animals. Results. Vaccination coverage of nomadic children 0-59 months of age increased, particularly among those never before vaccinated against polio. These increases occurred mostly in the intervention districts of Dourbali, from 2956 to 8164 vaccinated children, and Kyabe, from 7319 to 15 868. The number of first-time vaccinated nomadic children also increased the most in these districts, from 60 to 131 in Dourbali and from 1302 to 2973 in Kyabe. Coverage in the Massaguet district was only 37.7%. Conclusions. Our success was probably due to (1) appointment of staff to oversee implementation, (2) engagement of the national government and its partners, (3) participation of nomadic community leaders, (4) intersectoral collaboration between human and animal health services, and (5) flexibility and capacity of vaccinators to vaccinate when and where nomads were available. JF - Journal of Infectious Diseases AU - Ndiaye, Serigne M AU - Ahmed, Mahamat Abdoulaye AU - Denson, Melinda AU - Craig, Allen S AU - Kretsinger, Katrina AU - Cherif, Baharadine AU - Kandolo, Pierre AU - Moto, Daugla Doumagoum AU - Richelot, Ayangma AU - Tuma, Jude AD - Disease Eradication and Elimination Branch, Global Immunization Division, Centers for Disease Control and Prevention, MS A-04, Atlanta, GA 30333, scn3@cdc.gov Y1 - 2014/11/01/ PY - 2014 DA - 2014 Nov 01 SP - S74 EP - S84 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 210 SN - 0022-1899, 0022-1899 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - nomad health KW - vaccinations of mobile populations KW - vaccination outreach strategies KW - polio vaccination KW - Poliovirus KW - Age KW - Epidemics KW - Intervention KW - Children KW - Vaccination KW - Public health KW - Infectious diseases KW - Chad KW - Nomads KW - Vaccines KW - Outbreaks KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1687680142?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Polio+Outbreak+Among+Nomads+in+Chad%3A+Outbreak+Response+and+Lessons+Learned&rft.au=Ndiaye%2C+Serigne+M%3BAhmed%2C+Mahamat+Abdoulaye%3BDenson%2C+Melinda%3BCraig%2C+Allen+S%3BKretsinger%2C+Katrina%3BCherif%2C+Baharadine%3BKandolo%2C+Pierre%3BMoto%2C+Daugla+Doumagoum%3BRichelot%2C+Ayangma%3BTuma%2C+Jude&rft.aulast=Ndiaye&rft.aufirst=Serigne&rft.date=2014-11-01&rft.volume=210&rft.issue=&rft.spage=S74&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjit564 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-06-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Age; Epidemics; Nomads; Children; Vaccination; Public health; Poliovirus; Infectious diseases; Intervention; Outbreaks; Vaccines; Chad DO - http://dx.doi.org/10.1093/infdis/jit564 ER - TY - JOUR T1 - Molecular and Phenotypic Characterization of Vibrio navarrensis Isolates Associated with Human Illness AN - 1639993398; 20999678 AB - We characterized 18 Vibrio isolates, including 15 recovered from human clinical specimens, and found that they clustered with two previously characterized Vibrio navarrensis isolates in a phylogenetic analysis. Four of the 18 strains may represent a new Vibrio species, distinct from V. navarrensis. The potential role of V. navarrensis in human disease needs further investigation. JF - Journal of Clinical Microbiology AU - Gladney, Lori M AU - Tarr, Cheryl L AD - Enteric Diseases Laboratory Branch, Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging Zoonotic and Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, ctarr@cdc.gov. Y1 - 2014/11// PY - 2014 DA - November 2014 SP - 4070 EP - 4074 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 52 IS - 11 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Phylogeny KW - Vibrio KW - J 02310:Genetics & Taxonomy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1639993398?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Molecular+and+Phenotypic+Characterization+of+Vibrio+navarrensis+Isolates+Associated+with+Human+Illness&rft.au=Gladney%2C+Lori+M%3BTarr%2C+Cheryl+L&rft.aulast=Gladney&rft.aufirst=Lori&rft.date=2014-11-01&rft.volume=52&rft.issue=11&rft.spage=4070&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.01544-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-12-01 N1 - Number of references - 13 N1 - Last updated - 2016-07-20 N1 - SubjectsTermNotLitGenreText - Phylogeny; Vibrio DO - http://dx.doi.org/10.1128/JCM.01544-14 ER - TY - JOUR T1 - Optimizing Collection of Anopheles gambiae s.s. (Diptera: Culicidae) in Biogents Sentinel Traps AN - 1635017222; 20999995 AB - Surveillance of malaria vectors in Africa is most often accomplished using CDC-type light traps or human landing catches (HLCs). Over the past 30 yr, a variety of commercial and experimental mosquito traps have been developed for residential mosquito control or for improved surveillance of disease vector species, including the BG Sentinel (BGS) trap. To optimize collection of Anopheles gambiae Giles using this trap, BGS traps were modified with an opening (vent) added to the trap base to decrease exhaust airflow. Four traps configurations were tested with colony-reared host-seeking female An. gambiae in free-flying laboratory enclosures. Six attractant treatments (three attractants: BG-Lure, Limburger cheese, and a blank, with and without CO2) were tested concurrently. Across all trap-attractant combinations, significantly more mosquitoes (P < 0.05) were collected in standard, unmodified traps set upright (mean: 10.0) or upside down (9.8) than vented traps, whether upright (5.9) or upside down (7.0). The BG-Lure + CO2 and Limburger Cheese + CO2 bait combinations were more attractive than the other attractants tested alone. All attractant combinations collected significantly more mosquitoes than unbaited traps. Field studies are needed to determine if BG-Lure + CO2- or Limburger cheese + CO2-baited BGS traps are comparable with HLCs in collecting host-seeking An. gambiae. JF - Journal of Medical Entomology AU - Hoel, David F AU - Marika, Jake A AU - Dunford, James C AU - Irish, Seth R AU - Geier, Martin AU - Obermayr, Ulla AU - Wirtz, Robert A AD - Navy and Marine Corps Public Health Center Det., Centers for Disease Control and Prevention, 1600 Clifton Rd., Atlanta, G A 30329., VQP1@cdc.gov Y1 - 2014/11// PY - 2014 DA - November 2014 SP - 1268 EP - 1275 PB - Entomological Society of America, 9301 Annapolis Rd. Lanham MD 20706 United States VL - 51 IS - 6 SN - 0022-2585, 0022-2585 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Entomology Abstracts KW - Anopheles gambiae KW - BG-Sentinel trap KW - BG-Lure KW - Limburger cheese KW - Biological surveys KW - Light traps KW - Disease control KW - Vectors KW - Culicidae KW - Malaria KW - Pest control KW - Attractants KW - Hosts KW - Cheese KW - Exhausts KW - Disease transmission KW - Public health KW - Bait KW - Africa KW - Carbon dioxide KW - Diptera KW - Aquatic insects KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - Q1 08604:Stock assessment and management KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1635017222?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Medical+Entomology&rft.atitle=Optimizing+Collection+of+Anopheles+gambiae+s.s.+%28Diptera%3A+Culicidae%29+in+Biogents+Sentinel+Traps&rft.au=Hoel%2C+David+F%3BMarika%2C+Jake+A%3BDunford%2C+James+C%3BIrish%2C+Seth+R%3BGeier%2C+Martin%3BObermayr%2C+Ulla%3BWirtz%2C+Robert+A&rft.aulast=Hoel&rft.aufirst=David&rft.date=2014-11-01&rft.volume=51&rft.issue=6&rft.spage=1268&rft.isbn=&rft.btitle=&rft.title=Journal+of+Medical+Entomology&rft.issn=00222585&rft_id=info:doi/10.1603%2FME13045 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-12-01 N1 - Number of references - 54 N1 - Last updated - 2016-02-04 N1 - SubjectsTermNotLitGenreText - Biological surveys; Disease control; Pest control; Hosts; Carbon dioxide; Aquatic insects; Bait; Public health; Disease transmission; Light traps; Vectors; Malaria; Attractants; Cheese; Exhausts; Culicidae; Diptera; Anopheles gambiae; Africa DO - http://dx.doi.org/10.1603/ME13045 ER - TY - JOUR T1 - In Vitro Selection of Neisseria gonorrhoeae Mutants with Elevated MIC Values and Increased Resistance to Cephalosporins AN - 1635016202; 20999420 AB - Strains of Neisseria gonorrhoeae with mosaic penA genes bearing novel point mutations in penA have been isolated from ceftriaxone treatment failures. Such isolates exhibit significantly higher MIC values to third-generation cephalosporins. Here we report the in vitro isolation of two mutants with elevated MICs to cephalosporins. The first possesses a point mutation in the transpeptidase region of the mosaic penA gene, and the second contains an insertion mutation in pilQ. JF - Antimicrobial Agents & Chemotherapy AU - Johnson, Steven R AU - Grad, Yonatan AU - Ganakammal, Satishkumar Ranganathan AU - Burroughs, Mark AU - Frace, Mike AU - Lipsitch, Marc AU - Weil, Ryan AU - Trees, David AD - Division of STD Prevention, NCHHSTP, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, SBJ1@cdc.gov. Y1 - 2014/11// PY - 2014 DA - Nov 2014 SP - 6986 EP - 6989 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 58 IS - 11 SN - 0066-4804, 0066-4804 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Cephalosporins KW - Point mutation KW - PenA protein KW - Mosaics KW - Ceftriaxone KW - Minimum inhibitory concentration KW - Neisseria gonorrhoeae KW - J 02310:Genetics & Taxonomy KW - A 01380:Plant Protection, Fungicides & Seed Treatments UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1635016202?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=In+Vitro+Selection+of+Neisseria+gonorrhoeae+Mutants+with+Elevated+MIC+Values+and+Increased+Resistance+to+Cephalosporins&rft.au=Johnson%2C+Steven+R%3BGrad%2C+Yonatan%3BGanakammal%2C+Satishkumar+Ranganathan%3BBurroughs%2C+Mark%3BFrace%2C+Mike%3BLipsitch%2C+Marc%3BWeil%2C+Ryan%3BTrees%2C+David&rft.aulast=Johnson&rft.aufirst=Steven&rft.date=2014-11-01&rft.volume=58&rft.issue=11&rft.spage=6986&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.03082-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-12-01 N1 - Number of references - 35 N1 - Last updated - 2015-03-04 N1 - SubjectsTermNotLitGenreText - Cephalosporins; PenA protein; Point mutation; Mosaics; Ceftriaxone; Minimum inhibitory concentration; Neisseria gonorrhoeae DO - http://dx.doi.org/10.1128/AAC.03082-14 ER - TY - JOUR T1 - Optimism and Education Buffer the Effects of Syndemic Conditions on HIV Status Among African American Men Who Have Sex with Men AN - 1618159773; 20853791 AB - The present study sought to replicate effects of the number of syndemic psychosocial health conditions on sexual risk behavior and HIV infection among a sample of high-risk African American men who have sex with men (MSM) and to identify resilience factors that may buffer these effects. We used baseline data from an HIV risk-reduction trial to examine whether a higher number of syndemic conditions was associated with higher rates of self-reported sexual risk behavior and HIV infection. Using logistic regression models, we tested for interactions between number of syndemic conditions and several potential resilience factors to identify buffering effects. Replicating previous studies, we found significant associations between numbers of syndemic conditions and higher rates of sexual risk behavior and HIV infection. Surprisingly, we also replicated a previous finding (Stall et al., Am J Public Health, 93(6):939-942, 2003) that the effects of syndemic burden on HIV status fell off at the highest levels of syndemic conditions. Among a variety of potential resilience factors, two-optimism and education-buffered the syndemic effect on HIV prevalence. This is, to our knowledge, the first paper to identify resilience factors buffering against syndemic effects among MSM. It also constitutes a significant contribution to the literature regarding prevention among black MSM. These results point to the need to identify HIV-positive black MSM and provide effective treatment for them and to develop interventions addressing both syndemic and resilience factors. JF - AIDS and Behavior AU - O'Leary, Ann AU - Jemmott, John B AU - Stevens, Robin AU - Rutledge, Scott Edward AU - Icard, Larry D AD - Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road, MS E-37, Atlanta, GA, 30333, USA, aoleary@cdc.gov Y1 - 2014/11// PY - 2014 DA - Nov 2014 SP - 2080 EP - 2088 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 18 IS - 11 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - Acquired immune deficiency syndrome KW - Data processing KW - Intervention KW - Homosexuality KW - Infection KW - Sexual behavior KW - Public health KW - Models KW - Health risks KW - Education KW - Prevention KW - Human immunodeficiency virus KW - Buffers KW - Risk factors KW - Regression analysis KW - Risk groups KW - Ethnic groups KW - Sex KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1618159773?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Optimism+and+Education+Buffer+the+Effects+of+Syndemic+Conditions+on+HIV+Status+Among+African+American+Men+Who+Have+Sex+with+Men&rft.au=O%27Leary%2C+Ann%3BJemmott%2C+John+B%3BStevens%2C+Robin%3BRutledge%2C+Scott+Edward%3BIcard%2C+Larry+D&rft.aulast=O%27Leary&rft.aufirst=Ann&rft.date=2014-11-01&rft.volume=18&rft.issue=11&rft.spage=2080&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-014-0708-0 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-10-01 N1 - Number of references - 36 N1 - Last updated - 2014-12-11 N1 - SubjectsTermNotLitGenreText - Data processing; Risk factors; Regression analysis; Risk groups; Infection; Sexual behavior; Models; Public health; Sex; Health risks; Prevention; Education; Acquired immune deficiency syndrome; Human immunodeficiency virus; Buffers; Intervention; Homosexuality; Ethnic groups DO - http://dx.doi.org/10.1007/s10461-014-0708-0 ER - TY - JOUR T1 - Large outbreak of Legionnaires' disease and Pontiac fever at a military base AN - 1618148940; 20811039 AB - We investigated a mixed outbreak of Legionnaires' disease (LD) and Pontiac fever (PF) at a military base to identify the outbreak's environmental source as well as known legionellosis risk factors. Base workers with possible legionellosis were interviewed and, if consenting, underwent testing for legionellosis. A retrospective cohort study collected information on occupants of the buildings closest to the outbreak source. We identified 29 confirmed and probable LD and 38 PF cases. All cases were exposed to airborne pathogens from a cooling tower. Occupants of the building closest to the cooling tower were 6.9 [95% confidence interval (CI) 2.2-22.0] and 5.5 (95% CI 2.1-14.5) times more likely to develop LD and PF, respectively, than occupants of the next closest building. Thorough preventive measures and aggressive responses to outbreaks, including searching for PF cases in mixed legionellosis outbreaks, are essential for legionellosis control. JF - Epidemiology and Infection AU - Ambrose, J AU - Hampton, L M AU - Fleming-Dutra, Ke AU - Marten, C AU - McCLUSKY, C AU - Perry, C AU - Clemmons, Na AU - McCORMIC, Z AU - PEIK, S AU - Mancuso, J AU - Brown, E AU - Kozak, N AU - Travis, T AU - Lucas, C AU - Fields, B AU - Hicks, L AU - CERSOVSKY, S B AD - U.S. Army Public Health Command, Aberdeen Proving Ground, MD, USA, lhampton@cdc.gov Y1 - 2014/11// PY - 2014 DA - November 2014 SP - 2336 EP - 2346 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 142 IS - 11 SN - 0950-2688, 0950-2688 KW - Microbiology Abstracts B: Bacteriology; Risk Abstracts; Health & Safety Science Abstracts KW - Pathogens KW - Buildings KW - Legionnaire's disease KW - Fever KW - Cooling towers KW - Workers KW - Risk factors KW - Outbreaks KW - Military KW - Cooling systems KW - Occupational exposure KW - H 1000:Occupational Safety and Health KW - J 02400:Human Diseases KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1618148940?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Large+outbreak+of+Legionnaires%27+disease+and+Pontiac+fever+at+a+military+base&rft.au=Ambrose%2C+J%3BHampton%2C+L+M%3BFleming-Dutra%2C+Ke%3BMarten%2C+C%3BMcCLUSKY%2C+C%3BPerry%2C+C%3BClemmons%2C+Na%3BMcCORMIC%2C+Z%3BPEIK%2C+S%3BMancuso%2C+J%3BBrown%2C+E%3BKozak%2C+N%3BTravis%2C+T%3BLucas%2C+C%3BFields%2C+B%3BHicks%2C+L%3BCERSOVSKY%2C+S+B&rft.aulast=Ambrose&rft.aufirst=J&rft.date=2014-11-01&rft.volume=142&rft.issue=11&rft.spage=2336&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268813003440 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-10-01 N1 - Number of references - 38 N1 - Last updated - 2016-03-30 N1 - SubjectsTermNotLitGenreText - Fever; Workers; Cooling towers; Risk factors; Pathogens; Outbreaks; Military; Cooling systems; Buildings; Occupational exposure; Legionnaire's disease DO - http://dx.doi.org/10.1017/S0950268813003440 ER - TY - JOUR T1 - Inadequacy of IgM Antibody Tests for Diagnosis of Rocky Mountain Spotted Fever AN - 1753460829; PQ0002164938 AB - Among 13 suspected Rocky Mountain spotted fever (RMSF) cases identified through an enhanced surveillance program in Tennessee, antibodies to Rickettsia rickettsii were detected in 10 (77%) patients using a standard indirect immunofluorescent antibody (IFA) assay. Immunoglobulin M (IgM) antibodies were observed for 6 of 13 patients (46%) without a corresponding development of IgG, and for 3 of 10 patients (30%) at least 1 year post-onset. However, recent infection with a spotted fever group rickettsiae could not be confirmed for any patient, based on a lack of rising antibody titers in properly timed acute and convalescent serologic specimens, and negative findings by polymerase chain reaction testing. Case definitions used in national surveillance programs lack specificity and may capture cases that do not represent current rickettsial infections. Use of IgM antibodies should be reconsidered as a basis for diagnosis and public health reporting of RMSF and other spotted fever group rickettsiae in the United States. JF - American Journal of Tropical Medicine and Hygiene AU - McQuiston, Jennifer H AU - Wiedeman, Caleb AU - Singleton, Joseph AU - Carpenter, L Rand AU - McElroy, Kristina AU - Mosites, Emily AU - Chung, Ida AU - Kato, Cecilia AU - Morris, Kevin AU - Moncayo, Abelardo C AU - Porter, Susan AU - Dunn, John AD - Rickettsial Zoonoses Branch, Division of Vectorborne Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, fzh7@cdc.gov Y1 - 2014/10// PY - 2014 DA - October 2014 SP - 767 EP - 770 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 91 IS - 4 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology KW - Rocky Mountain spotted fever KW - Spotted fevers KW - Immunoglobulin G KW - Polymerase chain reaction KW - Rickettsia rickettsii KW - Infection KW - Immunoglobulin M KW - Public health KW - J 02400:Human Diseases KW - K 03310:Genetics & Taxonomy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1753460829?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Inadequacy+of+IgM+Antibody+Tests+for+Diagnosis+of+Rocky+Mountain+Spotted+Fever&rft.au=McQuiston%2C+Jennifer+H%3BWiedeman%2C+Caleb%3BSingleton%2C+Joseph%3BCarpenter%2C+L+Rand%3BMcElroy%2C+Kristina%3BMosites%2C+Emily%3BChung%2C+Ida%3BKato%2C+Cecilia%3BMorris%2C+Kevin%3BMoncayo%2C+Abelardo+C%3BPorter%2C+Susan%3BDunn%2C+John&rft.aulast=McQuiston&rft.aufirst=Jennifer&rft.date=2014-10-01&rft.volume=91&rft.issue=4&rft.spage=767&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0123 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-01-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Rocky Mountain spotted fever; Spotted fevers; Immunoglobulin G; Polymerase chain reaction; Infection; Immunoglobulin M; Public health; Rickettsia rickettsii DO - http://dx.doi.org/10.4269/ajtmh.14-0123 ER - TY - JOUR T1 - Case Series of Fatal Leptospira spp./Dengue Virus Co-Infections-Puerto Rico, 2010-2012 AN - 1727696654; PQ0002164936 AB - Co-infection with pathogens that cause acute febrile illness creates a diagnostic challenge as a result of overlapping clinical manifestations. Here, we describe four fatal cases of Leptospira species/dengue virus co-infection in Puerto Rico. Although all patients sought care early, antibiotic administration was delayed for most. Steroids were administered to all patients, in most cases before antibiotics. These cases show the need for clinicians evaluating patients in or recently returned from the tropics with acute febrile illness to consider both dengue and leptospirosis. Furthermore, they illustrate the need for nucleic acid- or antigen-based rapid diagnostic tests to enable timely patient diagnosis and management. In particular, antibiotic therapy should be initiated early for patients with suspected leptospirosis, and steroids should not be administered to patients with suspected dengue. JF - American Journal of Tropical Medicine and Hygiene AU - Rodriguez, Nicole M Perez AU - Galloway, Renee AU - Blau, Dianna M AU - Traxler, Rita AU - Bhatnagar, Julu AU - Zaki, Sherif R AU - Rivera, Aidsa AU - Torres, Jose V AU - Noyd, David AU - Santiago-Albizu, Xavier E AU - Garcia, Brenda Rivera AU - Tomashek, Kay M AU - Bower, William A AU - Sharp, Tyler M AD - Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico, tsharp@cdc.gov Y1 - 2014/10// PY - 2014 DA - October 2014 SP - 760 EP - 765 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 91 IS - 4 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources KW - Dengue virus KW - Leptospirosis KW - Leptospira KW - Therapy KW - Antibiotics KW - Steroid hormones KW - Pathogens KW - ASW, Caribbean Sea, Greater Antilles, Puerto Rico KW - Dengue KW - Hygiene KW - Steroids KW - Q1 08625:Non-edible products KW - J 02400:Human Diseases KW - Q5 08524:Public health, medicines, dangerous organisms KW - K 03310:Genetics & Taxonomy KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727696654?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Case+Series+of+Fatal+Leptospira+spp.%2FDengue+Virus+Co-Infections-Puerto+Rico%2C+2010-2012&rft.au=Rodriguez%2C+Nicole+M+Perez%3BGalloway%2C+Renee%3BBlau%2C+Dianna+M%3BTraxler%2C+Rita%3BBhatnagar%2C+Julu%3BZaki%2C+Sherif+R%3BRivera%2C+Aidsa%3BTorres%2C+Jose+V%3BNoyd%2C+David%3BSantiago-Albizu%2C+Xavier+E%3BGarcia%2C+Brenda+Rivera%3BTomashek%2C+Kay+M%3BBower%2C+William+A%3BSharp%2C+Tyler+M&rft.aulast=Rodriguez&rft.aufirst=Nicole+M&rft.date=2014-10-01&rft.volume=91&rft.issue=4&rft.spage=760&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0220 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Therapy; Antibiotics; Pathogens; Hygiene; Steroids; Leptospirosis; Dengue; Steroid hormones; Dengue virus; Leptospira; ASW, Caribbean Sea, Greater Antilles, Puerto Rico DO - http://dx.doi.org/10.4269/ajtmh.14-0220 ER - TY - JOUR T1 - Collection and Characterization of Samples for Establishment of a Serum Repository for Lyme Disease Diagnostic Test Development and Evaluation AN - 1635023007; 20856331 AB - Serological assays and a two-tiered test algorithm are recommended for laboratory confirmation of Lyme disease. In the United States, the sensitivity of two-tiered testing using commercially available serology-based assays is dependent on the stage of infection and ranges from 30% in the early localized disease stage to near 100% in late-stage disease. Other variables, including subjectivity in reading Western blots, compliance with two-tiered recommendations, use of different first- and second-tier test combinations, and use of different test samples, all contribute to variation in two-tiered test performance. The availability and use of sample sets from well-characterized Lyme disease patients and controls are needed to better assess the performance of existing tests and for development of improved assays. To address this need, the Centers for Disease Control and Prevention and the National Institutes of Health prospectively collected sera from patients at all stages of Lyme disease, as well as healthy donors and patients with look-alike diseases. Patients and healthy controls were recruited using strict inclusion and exclusion criteria. Samples from all included patients were retrospectively characterized by two-tiered testing. The results from two-tiered testing corroborated the need for novel and improved diagnostics, particularly for laboratory diagnosis of earlier stages of infection. Furthermore, the two-tiered results provide a baseline with samples from well-characterized patients that can be used in comparing the sensitivity and specificity of novel diagnostics. Panels of sera and accompanying clinical and laboratory testing results are now available to Lyme disease serological test users and researchers developing novel tests. JF - Journal of Clinical Microbiology AU - Molins, Claudia R AU - Sexton, Christopher AU - Young, John W AU - Ashton, Laura V AU - Pappert, Ryan AU - Beard, Charles B AU - Schriefer, Martin E AD - Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado, USA, mms7@cdc.gov. Y1 - 2014/10// PY - 2014 DA - October 2014 SP - 3755 EP - 3762 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 52 IS - 10 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Western blotting KW - Algorithms KW - Disease control KW - Borrelia KW - Language KW - Infection KW - Serological tests KW - Lyme disease KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1635023007?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Collection+and+Characterization+of+Samples+for+Establishment+of+a+Serum+Repository+for+Lyme+Disease+Diagnostic+Test+Development+and+Evaluation&rft.au=Molins%2C+Claudia+R%3BSexton%2C+Christopher%3BYoung%2C+John+W%3BAshton%2C+Laura+V%3BPappert%2C+Ryan%3BBeard%2C+Charles+B%3BSchriefer%2C+Martin+E&rft.aulast=Molins&rft.aufirst=Claudia&rft.date=2014-10-01&rft.volume=52&rft.issue=10&rft.spage=3755&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.01409-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-12-01 N1 - Number of references - 31 N1 - Last updated - 2016-07-20 N1 - SubjectsTermNotLitGenreText - Western blotting; Disease control; Algorithms; Language; Serological tests; Infection; Lyme disease; Borrelia DO - http://dx.doi.org/10.1128/JCM.01409-14 ER - TY - JOUR T1 - Prevalence of Chronic Obstructive Pulmonary Disease Among US Working Adults Aged 40 to 70 Years: National Health Interview Survey Data 2004 to 2011 AN - 1627961296; 20921234 AB - Objective: To estimate the prevalence and prevalence odds ratios of chronic obstructive pulmonary disease (COPD) among US workers by major occupational groups. Methods: The 2004 to 2011 National Health Interview Survey data for working adults 40 to 70 years old was analyzed to estimate the prevalence of COPD by major occupational groups. Logistic regression models were used to evaluate the associations between COPD (chronic bronchitis or emphysema) and occupations. Results: The estimated overall COPD prevalence was 4.2% (95% CI, 4.0 to 4.3). The odds of COPD were highest among workers in health care support occupations (prevalence odds ratio, 1.64; 95% CI, 1.25 to 2.14) followed by food preparation and serving-related occupations (prevalence odds ratio, 1.57; 95% CI, 1.20 to 2.06). Conclusions: Prevalence varied by occupations, suggesting workplace exposures may contribute to COPD. Preventive measures such as interventions to reduce smoking may reduce the prevalence of COPD. JF - Journal of Occupational and Environmental Medicine AU - Doney, Brent AU - Hnizdo, Eva AU - Syamlal, Girija AU - Kullman, Greg AU - Burchfiel, Cecil AU - Martin, Christopher J AU - Mujuru, Priscah AD - Division of Respiratory Disease Studies, Surveillance Branch, National Institute for Occupational Safety and Health, Mailstop HG 900.2, 1095 Willowdale Rd., Morgantown, WV 26505, bdoney@cdc.gov Y1 - 2014/10// PY - 2014 DA - Oct 2014 SP - 1088 EP - 1093 PB - Williams & Wilkins, 351 W. Camden St. Baltimore MD 21201 United States VL - 56 IS - 10 SN - 1076-2752, 1076-2752 KW - Health & Safety Science Abstracts KW - Smoking KW - Health care KW - Intervention KW - Occupational exposure KW - Chronic obstructive pulmonary disease KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1627961296?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Prevalence+of+Chronic+Obstructive+Pulmonary+Disease+Among+US+Working+Adults+Aged+40+to+70+Years%3A+National+Health+Interview+Survey+Data+2004+to+2011&rft.au=Doney%2C+Brent%3BHnizdo%2C+Eva%3BSyamlal%2C+Girija%3BKullman%2C+Greg%3BBurchfiel%2C+Cecil%3BMartin%2C+Christopher+J%3BMujuru%2C+Priscah&rft.aulast=Doney&rft.aufirst=Brent&rft.date=2014-10-01&rft.volume=56&rft.issue=10&rft.spage=1088&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0000000000000232 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-11-01 N1 - Last updated - 2015-04-02 N1 - SubjectsTermNotLitGenreText - Smoking; Health care; Intervention; Occupational exposure; Chronic obstructive pulmonary disease DO - http://dx.doi.org/10.1097/JOM.0000000000000232 ER - TY - CPAPER T1 - Why buy quiet? T2 - 2014 National Conference on Noise Control Engineering (Noise-Con 2014) AN - 1645185302; 6321715 JF - 2014 National Conference on Noise Control Engineering (Noise-Con 2014) AU - Hayden, Charles AU - McCleery, Trudi Y1 - 2014/09/08/ PY - 2014 DA - 2014 Sep 08 KW - Acoustics KW - Noise levels UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1645185302?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2014+National+Conference+on+Noise+Control+Engineering+%28Noise-Con+2014%29&rft.atitle=Why+buy+quiet%3F&rft.au=Hayden%2C+Charles%3BMcCleery%2C+Trudi&rft.aulast=Hayden&rft.aufirst=Charles&rft.date=2014-09-08&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2014+National+Conference+on+Noise+Control+Engineering+%28Noise-Con+2014%29&rft.issn=&rft_id=info:doi/ L2 - http://www.inceusa.org/nc14/documents/NC14_Program_UPDATED9-4-2014.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-11-30 N1 - Last updated - 2015-01-14 ER - TY - CPAPER T1 - National Surveillance Systems in the USA T2 - 54th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2014) AN - 1611579450; 6306242 JF - 54th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2014) AU - Sievert, Dawn Y1 - 2014/09/05/ PY - 2014 DA - 2014 Sep 05 KW - USA KW - Surveillance and enforcement UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1611579450?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=54th+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2014%29&rft.atitle=National+Surveillance+Systems+in+the+USA&rft.au=Sievert%2C+Dawn&rft.aulast=Sievert&rft.aufirst=Dawn&rft.date=2014-09-05&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=54th+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2014%29&rft.issn=&rft_id=info:doi/ L2 - http://www.icaac.org/index.php/scientific-program/course-program LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-30 N1 - Last updated - 2014-10-15 ER - TY - CPAPER T1 - Developing and Implementing the USPHS Guidelines T2 - 54th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2014) AN - 1611578322; 6306347 JF - 54th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2014) AU - Kuehnert, Matthew Y1 - 2014/09/05/ PY - 2014 DA - 2014 Sep 05 KW - Guidelines UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1611578322?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=54th+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2014%29&rft.atitle=Developing+and+Implementing+the+USPHS+Guidelines&rft.au=Kuehnert%2C+Matthew&rft.aulast=Kuehnert&rft.aufirst=Matthew&rft.date=2014-09-05&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=54th+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2014%29&rft.issn=&rft_id=info:doi/ L2 - http://www.icaac.org/index.php/scientific-program/course-program LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-30 N1 - Last updated - 2014-10-15 ER - TY - CPAPER T1 - The Pneumococcal Molecular Epidemiology Network (PMEN)/ Global Pneumococcal Strain Bank Initiatives T2 - 54th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2014) AN - 1611578225; 6306244 JF - 54th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2014) AU - McGee, Lesley Y1 - 2014/09/05/ PY - 2014 DA - 2014 Sep 05 KW - Epidemiology KW - Strains KW - Streptococcus pneumoniae UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1611578225?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=54th+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2014%29&rft.atitle=The+Pneumococcal+Molecular+Epidemiology+Network+%28PMEN%29%2F+Global+Pneumococcal+Strain+Bank+Initiatives&rft.au=McGee%2C+Lesley&rft.aulast=McGee&rft.aufirst=Lesley&rft.date=2014-09-05&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=54th+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2014%29&rft.issn=&rft_id=info:doi/ L2 - http://www.icaac.org/index.php/scientific-program/course-program LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-30 N1 - Last updated - 2014-10-15 ER - TY - CPAPER T1 - Healthcare-Associated Bloodborne Virus Transmission: More Common Than We Thought? T2 - 54th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2014) AN - 1611577764; 6306455 JF - 54th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2014) AU - Perz, Joseph Y1 - 2014/09/05/ PY - 2014 DA - 2014 Sep 05 KW - Chemotherapy KW - Oncology KW - Antimicrobial agents UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1611577764?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=54th+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2014%29&rft.atitle=Healthcare-Associated+Bloodborne+Virus+Transmission%3A+More+Common+Than+We+Thought%3F&rft.au=Perz%2C+Joseph&rft.aulast=Perz&rft.aufirst=Joseph&rft.date=2014-09-05&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=54th+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2014%29&rft.issn=&rft_id=info:doi/ L2 - http://www.icaac.org/index.php/scientific-program/course-program LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-30 N1 - Last updated - 2014-10-15 ER - TY - CPAPER T1 - Responding to the Ebola Outbreak in West Africa: Current Status and Lessons Learned T2 - 54th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2014) AN - 1611577588; 6306456 JF - 54th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2014) AU - Knust, Barbara Y1 - 2014/09/05/ PY - 2014 DA - 2014 Sep 05 KW - Africa KW - Outbreaks UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1611577588?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=54th+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2014%29&rft.atitle=Responding+to+the+Ebola+Outbreak+in+West+Africa%3A+Current+Status+and+Lessons+Learned&rft.au=Knust%2C+Barbara&rft.aulast=Knust&rft.aufirst=Barbara&rft.date=2014-09-05&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=54th+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2014%29&rft.issn=&rft_id=info:doi/ L2 - http://www.icaac.org/index.php/scientific-program/course-program LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-30 N1 - Last updated - 2014-10-15 ER - TY - CPAPER T1 - The Potential Role of Environmental Surfaces in the Transmission of Viral Pathogens in Healthcare T2 - 54th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2014) AN - 1611576426; 6306454 JF - 54th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2014) AU - Arduino, Matthew Y1 - 2014/09/05/ PY - 2014 DA - 2014 Sep 05 KW - Health care KW - Pathogens KW - Disease transmission UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1611576426?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=54th+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2014%29&rft.atitle=The+Potential+Role+of+Environmental+Surfaces+in+the+Transmission+of+Viral+Pathogens+in+Healthcare&rft.au=Arduino%2C+Matthew&rft.aulast=Arduino&rft.aufirst=Matthew&rft.date=2014-09-05&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=54th+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2014%29&rft.issn=&rft_id=info:doi/ L2 - http://www.icaac.org/index.php/scientific-program/course-program LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-30 N1 - Last updated - 2014-10-15 ER - TY - CPAPER T1 - Diagnosis of Noroviruses T2 - 54th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2014) AN - 1611576414; 6306379 JF - 54th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2014) AU - Vinje, Jan Y1 - 2014/09/05/ PY - 2014 DA - 2014 Sep 05 KW - Chemotherapy KW - Oncology KW - Antimicrobial agents KW - Norovirus UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1611576414?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=54th+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2014%29&rft.atitle=Diagnosis+of+Noroviruses&rft.au=Vinje%2C+Jan&rft.aulast=Vinje&rft.aufirst=Jan&rft.date=2014-09-05&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=54th+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2014%29&rft.issn=&rft_id=info:doi/ L2 - http://www.icaac.org/index.php/scientific-program/course-program LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-30 N1 - Last updated - 2014-10-15 ER - TY - JOUR T1 - Influenza Vaccination Coverage Among School Employees: Assessing Knowledge, Attitudes, and Behaviors AN - 1748688823 AB - Influenza can spread among students, teachers, and staff in school settings. Vaccination is the most effective method to prevent influenza. We determined 2012‐2013 influenza vaccination coverage among school employees, assessed knowledge and attitudes regarding the vaccine, and determined factors associated with vaccine receipt. We surveyed 412 (49%) of 841 employees at 1 suburban Ohio school district in March 2013. The Web‐based survey assessed personal and work characteristics, vaccine receipt, and knowledge and attitudes regarding the vaccine. Overall, 238 (58%) respondents reported getting the 2012‐2013 influenza vaccine. The most common reason for getting the vaccine was to protect oneself or one's family (87%). Beliefs that the vaccine was not needed (32%) or that it was not effective (21%) were the most common reasons for not getting it. Factors independently associated with vaccine receipt were having positive attitudes toward the vaccine, feeling external pressure to get it, and feeling personal control over whether to get it. Influenza vaccine coverage among school employees should be improved. Messages encouraging school employees to get the vaccine should address misconceptions about the vaccine. Employers should use methods to maximize employee vaccination as part of a comprehensive influenza prevention program. JF - The Journal of School Health AU - de Perio, Marie A AU - Wiegand, Douglas M AU - Brueck, Scott E AD - Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health mdeperio@cdc.gov mdeperio@cdc.gov zcd6@cdc.gov; Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health Y1 - 2014/09// PY - 2014 DA - Sep 2014 SP - 586 EP - 592 CY - Kent PB - Wiley Subscription Services, Inc. VL - 84 IS - 9 SN - 0022-4391 KW - Physical Fitness And Hygiene KW - Attitudes KW - Coverage KW - Immunization KW - Influenza KW - Job characteristics KW - Misconceptions KW - Personal control KW - Positive thought KW - Preventive programmes KW - Teachers KW - Ohio UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1748688823?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+School+Health&rft.atitle=Influenza+Vaccination+Coverage+Among+School+Employees%3A+Assessing+Knowledge%2C+Attitudes%2C+and+Behaviors&rft.au=de+Perio%2C+Marie+A%3BWiegand%2C+Douglas+M%3BBrueck%2C+Scott+E&rft.aulast=de+Perio&rft.aufirst=Marie&rft.date=2014-09-01&rft.volume=84&rft.issue=9&rft.spage=586&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+School+Health&rft.issn=00224391&rft_id=info:doi/10.1111%2Fjosh.12184 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2014-10-14 N1 - Last updated - 2016-05-12 N1 - SubjectsTermNotLitGenreText - Ohio DO - http://dx.doi.org/10.1111/josh.12184 ER - TY - JOUR T1 - Investigating the Important Correlates of Maternal Education and Childhood Malaria Infections AN - 1722170357; PQ0002099216 AB - The relationship between maternal education and child health has intrigued researchers for decades. This study explored the interaction between maternal education and childhood malaria infection. Cross-sectional survey data from three African countries were used. Descriptive analysis and multivariate logistic regression models were completed in line with identified correlates. Marginal effects and Oaxaca decomposition analysis on maternal education and childhood malaria infection were also estimated. Children with mothers whose education level was beyond primary school were 4.7% less likely to be malaria-positive (P < 0.001). The Oaxaca decomposition analysis exhibited an 8% gap in childhood malaria infection for educated and uneducated mothers. Over 60% of the gap was explained by differences in household wealth (26%), household place of domicile (21%), malaria transmission intensities (14%), and media exposure (12%). All other correlates accounted for only 27%. The full adjusted model showed a robust and significant relationship between maternal education and childhood malaria infection. JF - American Journal of Tropical Medicine and Hygiene AU - Njau, Joseph D AU - Stephenson, Rob AU - Menon, Manoj P AU - Kachur, S Patrick AU - McFarland, Deborah A AD - Department of Health Policy and Management, Rollins School of Public Health of the Emory University, Atlanta, Georgia, jnjau@cdc.gov Y1 - 2014/09// PY - 2014 DA - September 2014 SP - 509 EP - 519 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 91 IS - 3 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts C: Algology, Mycology & Protozoology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Human diseases KW - Data processing KW - Degradation KW - Malaria KW - Children KW - Infection KW - Decomposition KW - Education establishments KW - Models KW - Public health KW - Education KW - ISE, Mexico, Oaxaca KW - Regression analysis KW - Africa KW - Hygiene KW - K 03400:Human Diseases KW - J 02400:Human Diseases KW - Q1 08604:Stock assessment and management KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1722170357?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Investigating+the+Important+Correlates+of+Maternal+Education+and+Childhood+Malaria+Infections&rft.au=Njau%2C+Joseph+D%3BStephenson%2C+Rob%3BMenon%2C+Manoj+P%3BKachur%2C+S+Patrick%3BMcFarland%2C+Deborah+A&rft.aulast=Njau&rft.aufirst=Joseph&rft.date=2014-09-01&rft.volume=91&rft.issue=3&rft.spage=509&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.13-0713 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-02-04 N1 - SubjectsTermNotLitGenreText - Education; Human diseases; Degradation; Malaria; Hygiene; Education establishments; Public health; Data processing; Regression analysis; Infection; Children; Decomposition; Models; ISE, Mexico, Oaxaca; Africa DO - http://dx.doi.org/10.4269/ajtmh.13-0713 ER - TY - JOUR T1 - Federal environmental and occupational toxicology regulations and reporting requirements: a practical approach to what the medical toxicologist needs to know, part 1. AN - 1555627995; 25023223 AB - Toxicologists are often called upon to assist in environmental, industrial, occupational and public health assessments. Accordingly, medical toxicologists may find it prudent to be aware of applicable federal toxicological regulations and reporting requirements and of the roles of relevant federal agencies. These regulations are numerous, complex, and have evolved and expanded over time, making it difficult for toxicologists to sustain a current knowledge base. This article reviews the pertinent federal toxicological reporting requirements with regard to the Toxic Substances Control Act (TSCA), the Atomic Energy Act (AEA), the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), the Resource Conservation and Recovery Act (RCRA), the Clean Air Act, the Clean Water Act, the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), the Emergency Planning and Community Right to Know Act (EPCRA), the Occupational Safety and Health Act, the Department of Transportation, and information about the National Response Center. We reference internet-based government resources and offer direct links to applicable websites in an attempt to offer rapid and current sources of practical information. The format of the article is a series of hypothetical scenarios followed by commentary. Discussions of the Safe Drinking Water Act, the Food, Drug, and Cosmetic Act, and the Dietary Supplement Health and Education Act are beyond the scope of this paper. For those desiring a more in-depth discussion of the relevant federal environmental laws and statutes and applicable case law, the reader is directed to resources such as the Environmental Law Handbook, the websites of individual laws found at www.epa.gov and the decisions of individual courts of appeal. It is our hope that this article provides not only useful practical information for the practicing toxicologist but also serves as a key reference for medical toxicology core content on environmental laws and regulations. JF - Journal of medical toxicology : official journal of the American College of Medical Toxicology AU - Schwartz, Michael D AU - Dell'Aglio, Damon M AU - Nickle, Richard AU - Hornsby-Myers, Jennifer AD - National Center for Environmental Health, Office of Environmental Health Emergencies, Centers for Disease Control and Prevention, 1600 Clifton Rd., MS F-09, Atlanta, GA, 30333, USA, aeo8@cdc.gov. Y1 - 2014/09// PY - 2014 DA - September 2014 SP - 319 EP - 330 VL - 10 IS - 3 KW - Hazardous Waste KW - 0 KW - Index Medicus KW - United States KW - Hazardous Waste -- legislation & jurisprudence KW - United States Environmental Protection Agency KW - Humans KW - Occupational Health -- legislation & jurisprudence KW - Toxicology -- legislation & jurisprudence KW - Government Agencies KW - Ecotoxicology -- legislation & jurisprudence UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1555627995?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+medical+toxicology+%3A+official+journal+of+the+American+College+of+Medical+Toxicology&rft.atitle=Federal+environmental+and+occupational+toxicology+regulations+and+reporting+requirements%3A+a+practical+approach+to+what+the+medical+toxicologist+needs+to+know%2C+part+1.&rft.au=Schwartz%2C+Michael+D%3BDell%27Aglio%2C+Damon+M%3BNickle%2C+Richard%3BHornsby-Myers%2C+Jennifer&rft.aulast=Schwartz&rft.aufirst=Michael&rft.date=2014-09-01&rft.volume=10&rft.issue=3&rft.spage=319&rft.isbn=&rft.btitle=&rft.title=Journal+of+medical+toxicology+%3A+official+journal+of+the+American+College+of+Medical+Toxicology&rft.issn=1937-6995&rft_id=info:doi/10.1007%2Fs13181-014-0410-7 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2015-09-02 N1 - Date created - 2014-08-23 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Cited By: Environ Health Perspect. 1979 Oct;32:279-84 [540601] Regul Toxicol Pharmacol. 1997 Apr;25(2):158-65 [9185891] Occup Med. 1996 Jan-Mar;11(1):173-92 [8907061] J Environ Health. 1985 Nov-Dec;48(3):133-7 [10275155] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1007/s13181-014-0410-7 ER - TY - JOUR T1 - Influenza-like Illness, the Time to Seek Healthcare, and Influenza Antiviral Receipt During the 2010-2011 Influenza Season- United States AN - 1618149249; 20800455 AB - Background. Few data exist describing healthcare-seeking behaviors among persons with influenza-like illness (ILI) or adherence to influenza antiviral treatment recommendations. Methods. We analyzed adult responses to the Behavioral Risk Factor Surveillance System in 31 states and the District of Columbia (DC) and pediatric responses in 25 states and DC for January-April 2011 by demographics and underlying health conditions. Results. Among 75 088 adult and 15 649 child respondents, 8.9% and 33.9%, respectively, reported ILI. ILI was more frequent among adults with asthma (16%), chronic obstruction pulmonary disease (COPD; 26%), diabetes (12%), heart disease (19%), kidney disease (16%), or obesity (11%). Forty-five percent of adults and 57% of children sought healthcare for ILI. Thirty-five percent of adults sought care [< or =]2 days after ILI onset. Seeking care < or =2 days was more frequent among adults with COPD (48%) or heart disease (55%). Among adults with a self-reported physician diagnosis of influenza, 34% received treatment with antiviral medications. The only underlying health condition with a higher rate of treatment was diabetes (46%). Conclusions. Adults with underlying health conditions were more likely to report ILI, but the majority did not seek care promptly, missing opportunities for early influenza antiviral treatment. JF - Journal of Infectious Diseases AU - Biggerstaff, Matthew AU - Jhung, Michael A AU - Reed, Carrie AU - Fry, Alicia M AU - Balluz, Lina AU - Finelli, Lyn AD - Epidemiology and Prevention Branch, Influenza Division, National Center for Immunization and Respiratory Disease; Centers for Disease Control and Prevention, 1600 Clifton Road NE MS A-32, Atlanta, GA 30333, mbiggerstaff@cdc.gov Y1 - 2014/08/15/ PY - 2014 DA - 2014 Aug 15 SP - 535 EP - 544 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 210 IS - 4 SN - 0022-1899, 0022-1899 KW - Risk Abstracts; Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - healthcare-seeking behavior KW - influenza KW - influenza antiviral treatment KW - time to seek healthcare KW - Respiratory diseases KW - Demography KW - Influenza KW - Infectious diseases KW - Risk factors KW - Drugs KW - Heart diseases KW - Obesity KW - Data processing KW - Pediatrics KW - Lung diseases KW - Kidney diseases KW - Asthma KW - Children KW - Chronic obstructive pulmonary disease KW - Diabetes mellitus KW - USA KW - Health care KW - Kidney KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1618149249?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Influenza-like+Illness%2C+the+Time+to+Seek+Healthcare%2C+and+Influenza+Antiviral+Receipt+During+the+2010-2011+Influenza+Season-+United+States&rft.au=Biggerstaff%2C+Matthew%3BJhung%2C+Michael+A%3BReed%2C+Carrie%3BFry%2C+Alicia+M%3BBalluz%2C+Lina%3BFinelli%2C+Lyn&rft.aulast=Biggerstaff&rft.aufirst=Matthew&rft.date=2014-08-15&rft.volume=210&rft.issue=4&rft.spage=535&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiu224 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-10-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Obesity; Data processing; Pediatrics; Kidney diseases; Lung diseases; Asthma; Children; Chronic obstructive pulmonary disease; Influenza; Diabetes mellitus; Demography; Risk factors; Heart diseases; Respiratory diseases; Health care; Infectious diseases; Kidney; Drugs; USA DO - http://dx.doi.org/10.1093/infdis/jiu224 ER - TY - JOUR T1 - An Evaluation of Methods for Assessing the Quality of Case Management for Inpatients with Malaria in Benin AN - 1727697297; PQ0002140019 AB - To improve healthcare quality for hospitalized patients with malaria in Benin, a feasible and valid evaluation method is needed. Because observation of inpatients is challenging, chart abstraction is an attractive option. However, the quality of inpatient charts is unknown. We employed three methods in five hospitals to assess 11 signs of malaria and severe disease: 1) chart abstraction (probability sample of inpatients), 2) chart abstraction compared to interviews of inpatients and health workers (HWs), and 3) abstraction from charts of recently discharged inpatients compared to interviews with HWs. Method 1 showed that of 473 malaria signs (from 43 charts), 178 (38%, 95% confidence interval 24-51%) were documented. Method 2 showed that 96% (45 of 47) of documented signs were valid. Method 3 suggests that 65% (36 of 55) of non-documented signs were assessed (but not documented) by HWs. Chart abstraction was feasible and documented data were valid, but results should be interpreted cautiously in consideration of low levels of documentation. JF - American Journal of Tropical Medicine and Hygiene AU - Mace, Kimberly E AU - Gueye, Abdou Salam AU - Lynch, Michael F AU - Tassiba, Esther M AU - Rowe, Alexander K AD - Malaria Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, KMace@cdc.gov Y1 - 2014/08// PY - 2014 DA - August 2014 SP - 354 EP - 360 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 91 IS - 2 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts C: Algology, Mycology & Protozoology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts KW - Human diseases KW - Data processing KW - Malaria KW - Public health KW - Methodology KW - Workers KW - Health care KW - Benin KW - Hygiene KW - Hospitals KW - K 03400:Human Diseases KW - J 02400:Human Diseases KW - H 1000:Occupational Safety and Health KW - Q1 08604:Stock assessment and management KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727697297?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=An+Evaluation+of+Methods+for+Assessing+the+Quality+of+Case+Management+for+Inpatients+with+Malaria+in+Benin&rft.au=Mace%2C+Kimberly+E%3BGueye%2C+Abdou+Salam%3BLynch%2C+Michael+F%3BTassiba%2C+Esther+M%3BRowe%2C+Alexander+K&rft.aulast=Mace&rft.aufirst=Kimberly&rft.date=2014-08-01&rft.volume=91&rft.issue=2&rft.spage=354&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.13-0389 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-02-04 N1 - SubjectsTermNotLitGenreText - Human diseases; Malaria; Hygiene; Methodology; Public health; Workers; Data processing; Hospitals; Health care; Benin DO - http://dx.doi.org/10.4269/ajtmh.13-0389 ER - TY - JOUR T1 - Effect of Aerial Insecticide Spraying on West Nile Virus Disease-North-Central Texas, 2012 AN - 1727694667; PQ0002140000 AB - During 2012, four north-central Texas counties experienced high West Nile virus (WNV) disease incidence. Aerial insecticide spraying was conducted in two counties. To evaluate the effect of spraying on WNV disease, we calculated incidence rate ratios (IRRs) in treated and untreated areas by comparing incidence before and after spraying; for unsprayed areas, before and after periods were defined by using dates from a corresponding sprayed area. In treated areas, WNV neuroinvasive disease incidence before and after spraying was 7.31/100,000 persons and 0.28/100,000 persons, respectively; the IRR was 26.42 (95% confidence interval [CI]: 12.42-56.20). In untreated areas, the before and after incidence was 4.80/100,000 persons and 0.45/100,000 persons, respectively; the IRR was 10.57 (95% CI: 6.11-18.28). The ratio of IRRs was 2.50 (95% CI: 0.98-6.35). Disease incidence decreased in both areas, but the relative change was greater in aerial-sprayed areas. JF - American Journal of Tropical Medicine and Hygiene AU - Ruktanonchai, Duke J AU - Stonecipher, Shelley AU - Lindsey, Nicole AU - McAllister, Janet AU - Pillai, Satish K AU - Horiuchi, Kalanthe AU - Delorey, Mark AU - Biggerstaff, Brad J AU - Sidwa, Tom AU - Zoretic, James AU - Nasci, Roger AU - Fischer, Marc AU - Hills, Susan L AD - Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, Shills@cdc.gov Y1 - 2014/08// PY - 2014 DA - August 2014 SP - 240 EP - 245 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 91 IS - 2 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - ASW, USA, Texas KW - Invasiveness KW - Insecticides KW - Spraying KW - Hygiene KW - West Nile virus KW - K 03340:Effects of Physical & Chemical Factors KW - J 02410:Animal Diseases KW - V 22410:Animal Diseases KW - Q1 08485:Species interactions: pests and control KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727694667?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Effect+of+Aerial+Insecticide+Spraying+on+West+Nile+Virus+Disease-North-Central+Texas%2C+2012&rft.au=Ruktanonchai%2C+Duke+J%3BStonecipher%2C+Shelley%3BLindsey%2C+Nicole%3BMcAllister%2C+Janet%3BPillai%2C+Satish+K%3BHoriuchi%2C+Kalanthe%3BDelorey%2C+Mark%3BBiggerstaff%2C+Brad+J%3BSidwa%2C+Tom%3BZoretic%2C+James%3BNasci%2C+Roger%3BFischer%2C+Marc%3BHills%2C+Susan+L&rft.aulast=Ruktanonchai&rft.aufirst=Duke&rft.date=2014-08-01&rft.volume=91&rft.issue=2&rft.spage=240&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0072 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Insecticides; Hygiene; Invasiveness; Spraying; West Nile virus; ASW, USA, Texas DO - http://dx.doi.org/10.4269/ajtmh.14-0072 ER - TY - JOUR T1 - Quantitation of five organophosphoms nerve agent metabolites in serum using hydrophilic interaction liquid chromatography and tandem mass spectrometry AN - 1620045681; 20641815 AB - Although nerve agent use is prohibited, concerns remain for human exposure to nerve agents during decommissioning, research, and warfare. Exposure can be detected through the analysis of hydrolysis products in urine as well as blood. An analytical method to detect exposure to five nerve agents, including VX, VR (Russian VX), GB (sarin), GD (soman), and GF (cyclosarin), through the analysis of the hydrolysis products, which are the primary metabolites, in serum has been developed and characterized. This method uses solid-phase extraction coupled with high-performance liquid chromatography for separation and isotopic dilution tandem mass spectrometry for detection. An uncommon buffer of ammonium fluoride was used to enhance ionization and improve sensitivity when coupled with hydrophilic interaction liquid chromatography resulting in detection limits from 0.3 to 0.5 ng/mL. The assessment of two quality control samples demonstrated high accuracy (101-105%) and high precision (5-8%) for the detection of these five nerve agent hydrolysis products in serum. JF - Analytical and Bioanalytical Chemistry AU - Hamelin, Elizabeth I AU - Schulze, Nicholas D AU - Shaner, Rebecca L AU - Coleman, Rebecca M AU - Lawrence, Richard J AU - Crow, Brian S AU - Jakubowski, E M AU - Johnson, Rudolph C AD - Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Hwy, Atlanta, GA 30341, USA, ehamehn@cdc.gov PY - 2014 SP - 5195 EP - 5202 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 406 IS - 21 SN - 1618-2642, 1618-2642 KW - Aqualine Abstracts; Water Resources Abstracts KW - Organophosphoms nerve agents KW - Metabolites KW - Serum KW - Exposure KW - Mass Spectrometry KW - Hydrolysis KW - Blood KW - Assessments KW - Analytical Methods KW - Urine KW - Liquid Chromatography KW - AQ 00001:Water Resources and Supplies KW - SW 0810:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1620045681?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytical+and+Bioanalytical+Chemistry&rft.atitle=Quantitation+of+five+organophosphoms+nerve+agent+metabolites+in+serum+using+hydrophilic+interaction+liquid+chromatography+and+tandem+mass+spectrometry&rft.au=Hamelin%2C+Elizabeth+I%3BSchulze%2C+Nicholas+D%3BShaner%2C+Rebecca+L%3BColeman%2C+Rebecca+M%3BLawrence%2C+Richard+J%3BCrow%2C+Brian+S%3BJakubowski%2C+E+M%3BJohnson%2C+Rudolph+C&rft.aulast=Hamelin&rft.aufirst=Elizabeth&rft.date=2014-08-01&rft.volume=406&rft.issue=21&rft.spage=5195&rft.isbn=&rft.btitle=&rft.title=Analytical+and+Bioanalytical+Chemistry&rft.issn=16182642&rft_id=info:doi/10.1007%2Fs00216-014-7702-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-12-01 N1 - Number of references - 20 N1 - Last updated - 2016-01-21 N1 - SubjectsTermNotLitGenreText - Blood; Mass Spectrometry; Assessments; Urine; Analytical Methods; Exposure; Liquid Chromatography; Metabolites; Hydrolysis DO - http://dx.doi.org/10.1007/s00216-014-7702-2 ER - TY - JOUR T1 - An enhanced butyrylcholinesterase method to measure organophosphorus nerve agent exposure in humans AN - 1620035997; 20641814 AB - Organophosphorus nerve agent (OPNA) adducts to butyrylcholinesterase (BChE) can be used to confirm exposure in humans. A highly accurate method to detect G- and V-series OPNA adducts to BChE in 75 mu L of filtered blood, serum, or plasma has been developed using immunomagnetic separation (IMS) coupled with liquid chromatography tandem mass spectrometry (LC-MS/MS). The reported IMS method captures >88 % of the BChE in a specimen and corrects for matrix effects on peptide calibrators. The optimized method has been used to quantify baseline BChE levels (unadducted and OPNA-adducted) in a matched-set of serum, plasma, and whole blood (later processed in-house for plasma content) from 192 unexposed individuals to determine the interchangeability of the tested matrices. The results of these measurements demonstrate the ability to accurately measure BChE regardless of the format of the blood specimen received. Criteria for accepting or denying specimens were established through a series of sample stability and processing experiments. The results of these efforts are an optimized and rugged method that is transferrable to other laboratories and an increased understanding of the BChE biomarker in matrix. JF - Analytical and Bioanalytical Chemistry AU - Pantazides, Brooke G AU - Watson, Caroline M AU - Carter, Melissa D AU - Crow, Brian S AU - Perez, Jonas W AU - Blake, Thomas A AU - Thomas, Jerry D AU - Johnson, Rudolph C AD - Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, Atlanta, GA 30341, USA, rmj6@cdc.gov PY - 2014 SP - 5187 EP - 5194 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 406 IS - 21 SN - 1618-2642, 1618-2642 KW - Aqualine Abstracts; Water Resources Abstracts KW - Organophosphorus nerve agent KW - Butyrylcholinesterase KW - Cholinesterase inhibitors KW - Protein adduct KW - Immunomagnetic separation KW - Bioindicators KW - Testing Procedures KW - Mass Spectrometry KW - Laboratories KW - Blood KW - Exposure KW - Liquid Chromatography KW - Peptides KW - AQ 00001:Water Resources and Supplies KW - SW 0810:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1620035997?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytical+and+Bioanalytical+Chemistry&rft.atitle=An+enhanced+butyrylcholinesterase+method+to+measure+organophosphorus+nerve+agent+exposure+in+humans&rft.au=Pantazides%2C+Brooke+G%3BWatson%2C+Caroline+M%3BCarter%2C+Melissa+D%3BCrow%2C+Brian+S%3BPerez%2C+Jonas+W%3BBlake%2C+Thomas+A%3BThomas%2C+Jerry+D%3BJohnson%2C+Rudolph+C&rft.aulast=Pantazides&rft.aufirst=Brooke&rft.date=2014-08-01&rft.volume=406&rft.issue=21&rft.spage=5187&rft.isbn=&rft.btitle=&rft.title=Analytical+and+Bioanalytical+Chemistry&rft.issn=16182642&rft_id=info:doi/10.1007%2Fs00216-014-7718-7 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-12-01 N1 - Number of references - 30 N1 - Last updated - 2016-01-21 N1 - SubjectsTermNotLitGenreText - Testing Procedures; Bioindicators; Mass Spectrometry; Blood; Laboratories; Exposure; Liquid Chromatography; Peptides DO - http://dx.doi.org/10.1007/s00216-014-7718-7 ER - TY - JOUR T1 - LESSONS LEARNED WHILE PREPARING A TAILORED, SELF-HELP, TECHNOLOGY-DRIVEN INTERVENTION FOR NATIONAL DISSEMINATION AN - 1566830040; 20657622 AB - Tailored health interventions have been found to be effective in various areas of health promotion because of their delivery of customized content, which focuses the prevention messages more closely on the individual's risk behavior. However, the use of tailored interventions in the prevention of STD/HIV has been limited, and there is a void in the literature on translating tailored interventions into practice. This paper discusses the process of translating a tailored, self-help, technology-driven STD/HIV prevention intervention from research-to-practice. Three agencies were selected during the translation process to test the intervention materials and provided valuable lessons learned for translating a tailored intervention into practice. A racially diverse group of more than 250 women in six states participated in the intervention during this pilot test. Lessons learned for research-to-practice efforts for tailored interventions are presented, including expanding the reach of such interventions by making them more compatible for mobile technology. JF - AIDS Education and Prevention AU - Wilkes, Aisha L AU - Jones, Patricia L AU - Morales-Reid, Bethsy AU - Ramos, Bertha AU - Vega, Miriam Y AU - Scholes, Delia AU - Farrell, David AU - Edwards, Arlene AU - Polk, LaShaun AD - Centers for Disease Control and Prevention, 1600 Clifton Rd., NE, Mailstop E-37, Atlanta, GA 30329, awilkes@cdc.gov Y1 - 2014/08// PY - 2014 DA - Aug 2014 SP - 281 EP - 295 PB - Guilford Publications, Inc., 72 Spring Street, 4th Floor New York NY 10012 United States VL - 26 IS - 4 SN - 0899-9546, 0899-9546 KW - Risk Abstracts; Virology & AIDS Abstracts KW - Translation KW - Prevention KW - Acquired immune deficiency syndrome KW - Education KW - Human immunodeficiency virus KW - Intervention KW - Risk taking KW - Sexually transmitted diseases KW - Health promotion KW - Technology KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1566830040?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+Education+and+Prevention&rft.atitle=LESSONS+LEARNED+WHILE+PREPARING+A+TAILORED%2C+SELF-HELP%2C+TECHNOLOGY-DRIVEN+INTERVENTION+FOR+NATIONAL+DISSEMINATION&rft.au=Wilkes%2C+Aisha+L%3BJones%2C+Patricia+L%3BMorales-Reid%2C+Bethsy%3BRamos%2C+Bertha%3BVega%2C+Miriam+Y%3BScholes%2C+Delia%3BFarrell%2C+David%3BEdwards%2C+Arlene%3BPolk%2C+LaShaun&rft.aulast=Wilkes&rft.aufirst=Aisha&rft.date=2014-08-01&rft.volume=26&rft.issue=4&rft.spage=281&rft.isbn=&rft.btitle=&rft.title=AIDS+Education+and+Prevention&rft.issn=08999546&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Number of references - 30 N1 - Last updated - 2014-12-11 N1 - SubjectsTermNotLitGenreText - Translation; Education; Acquired immune deficiency syndrome; Prevention; Human immunodeficiency virus; Risk taking; Intervention; Sexually transmitted diseases; Technology; Health promotion ER - TY - JOUR T1 - Role of FKS Mutations in Candida glabrata: MIC Values, Echinocandin Resistance, and Multidrug Resistance AN - 1560113089; 20602580 AB - Candida glabrata is the second leading cause of candidemia in U.S. hospitals. Current guidelines suggest that an echinocandin be used as the primary therapy for the treatment of C. glabrata disease due to the high rate of resistance to fluconazole. Recent case reports indicate that C. glabrata resistance to echinocandins may be increasing. We performed susceptibility testing on 1,380 isolates of C. glabrata collected between 2008 and 2013 from four U.S. cities, Atlanta, Baltimore, Knoxville, and Portland. Our analysis showed that 3.1%, 3.3%, and 3.6% of the isolates were resistant to anidulafungin, caspofungin, and micafungin, respectively. We screened 1,032 of these isolates, including all 77 that had either a resistant or intermediate MIC value with respect to at least one echinocandin, for mutations in the hot spot regions of FKS1 and FKS2, the major mechanism of echinocandin resistance. Fifty-one isolates were identified with hot spot mutations, 16 in FKS1 and 35 in FKS2. All of the isolates with an FKS mutation except one were resistant to at least one echinocandin by susceptibility testing. Of the isolates resistant to at least one echinocandin, 36% were also resistant to fluconazole. Echinocandin resistance among U.S. C. glabrata isolates is a concern, especially in light of the fact that one-third of those isolates may be multidrug resistant. Further monitoring of U.S. C. glabrata isolates for echinocandin resistance is warranted. JF - Antimicrobial Agents & Chemotherapy AU - Pham, Cau D AU - Iqbal, Naureen AU - Bolden, Carol B AU - Kuykendall, Randall J AU - Harrison, Lee H AU - Farley, Monica M AU - Schaffner, William AU - Beldavs, Zintars G AU - Chiller, Tom M AU - Park, Benjamin J AD - Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, gyi2@cdc.gov. Y1 - 2014/08// PY - 2014 DA - Aug 2014 SP - 4690 EP - 4696 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 58 IS - 8 SN - 0066-4804, 0066-4804 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - fluconazole KW - Candidemia KW - Case reports KW - micafungin KW - Candida glabrata KW - Caspofungin KW - Multidrug resistance KW - echinocandins KW - Mutation KW - Minimum inhibitory concentration KW - Hospitals KW - A 01380:Plant Protection, Fungicides & Seed Treatments KW - K 03400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1560113089?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Role+of+FKS+Mutations+in+Candida+glabrata%3A+MIC+Values%2C+Echinocandin+Resistance%2C+and+Multidrug+Resistance&rft.au=Pham%2C+Cau+D%3BIqbal%2C+Naureen%3BBolden%2C+Carol+B%3BKuykendall%2C+Randall+J%3BHarrison%2C+Lee+H%3BFarley%2C+Monica+M%3BSchaffner%2C+William%3BBeldavs%2C+Zintars+G%3BChiller%2C+Tom+M%3BPark%2C+Benjamin+J&rft.aulast=Pham&rft.aufirst=Cau&rft.date=2014-08-01&rft.volume=58&rft.issue=8&rft.spage=4690&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.03255-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Number of references - 42 N1 - Last updated - 2014-10-30 N1 - SubjectsTermNotLitGenreText - fluconazole; Case reports; Candidemia; micafungin; Caspofungin; Multidrug resistance; echinocandins; Minimum inhibitory concentration; Mutation; Hospitals; Candida glabrata DO - http://dx.doi.org/10.1128/AAC.03255-14 ER - TY - JOUR T1 - Flight Attendant Radiation Dose from Solar Particle Events AN - 1560106981; 20588630 AB - Introduction: Research has suggested that work as a flight attendant may be related to increased risk for reproductive health effects. Air cabin exposures that may influence reproductive health include radiation dose from galactic cosmic radiation and solar particle events. This paper describes the assessment of radiation dose accrued during solar particle events as part of a reproductive health study of flight attendants. Methods: Solar storm data were obtained from the National Oceanic and Atmospheric Administration Space Weather Prediction Center list of solar proton events affecting the Earth environment to ascertain storms relevant to the two study periods (1992-1996 and 1999-2001). Radiation dose from exposure to solar energetic particles was estimated using the NAIRAS model in conjunction with galactic cosmic radiation dose calculated using the CARI-6P computer program. Results: Seven solar particle events were determined to have potential for significant radiation exposure, two in the first study period and five in the second study period, and over-lapped with 24,807 flight segments. Absorbed (and effective) flight segment doses averaged 6.5 mu Gy (18 mu Sv) and 3.1 mu Gy (8.3 mu Sv) for the first and second study periods, respectively. Maximum doses were as high as 440 mu Gy (1.2 mSv) and 20 flight segments had doses greater than 190 mu Gy (0.5 mSv). Discussion: During solar particle events, a pregnant flight attendant could potentially exceed the equivalent dose limit to the conceptus of 0.5 mSv in a month recommended by the National Council on Radiation Protection and Measurements. JF - Aviation, Space, and Environmental Medicine AU - Anderson, Jeri L AU - Mertens, Christopher J AU - Grajewski, Barbara AU - Luo, Lian AU - Tseng, Chih-yu AU - Cassinelli, Rick T, II AD - Langley Research Center, National Aeronautics and Space Administration, Hampton, VA; National Institute for Occupational Safety and Health, 4676 Columbia Pkwy, MS R-14, Cincinnati, OH 45226, JLAnderson@cdc.gov Y1 - 2014/08// PY - 2014 DA - Aug 2014 SP - 828 EP - 832 PB - Aerospace Medical Association, 320 S. Henry St. Alexandria VA 22314-3579 United States VL - 85 IS - 8 SN - 0095-6562, 0095-6562 KW - Health & Safety Science Abstracts; Risk Abstracts KW - absorbed dose KW - effective dose KW - conceptus KW - reproductive health KW - Prediction KW - Risk assessment KW - Weather KW - Computer programs KW - Radiation KW - Cosmic radiation KW - Reproduction KW - Particulates KW - Storms KW - Councils KW - Pregnancy KW - R2 23020:Technological risks KW - H 2000:Transportation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1560106981?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aviation%2C+Space%2C+and+Environmental+Medicine&rft.atitle=Flight+Attendant+Radiation+Dose+from+Solar+Particle+Events&rft.au=Anderson%2C+Jeri+L%3BMertens%2C+Christopher+J%3BGrajewski%2C+Barbara%3BLuo%2C+Lian%3BTseng%2C+Chih-yu%3BCassinelli%2C+Rick+T%2C+II&rft.aulast=Anderson&rft.aufirst=Jeri&rft.date=2014-08-01&rft.volume=85&rft.issue=8&rft.spage=828&rft.isbn=&rft.btitle=&rft.title=Aviation%2C+Space%2C+and+Environmental+Medicine&rft.issn=00956562&rft_id=info:doi/10.3357%2FASEM.3989.2014 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Number of references - 22 N1 - Last updated - 2015-04-02 N1 - SubjectsTermNotLitGenreText - Risk assessment; Prediction; Computer programs; Weather; Radiation; Cosmic radiation; Reproduction; Particulates; Councils; Storms; Pregnancy DO - http://dx.doi.org/10.3357/ASEM.3989.2014 ER - TY - JOUR T1 - Measurement of mercury species in human blood using triple spike isotope dilution with SPME-GC-ICP-DRC-MS. AN - 1545416124; 24948088 AB - The measurement of different mercury compounds in human blood can provide valuable information about the type of mercury exposure. To this end, our laboratory developed a biomonitoring method for the quantification of inorganic (iHg), methyl (MeHg), and ethyl (EtHg) mercury in whole blood using a triple-spike isotope dilution (TSID) quantification method employing capillary gas chromatography (GC) and inductively coupled dynamic reaction cell mass spectrometry (ICP-DRC-MS). We used a robotic CombiPAL(®) sample handling station featuring twin fiber-based solid-phase microextraction (SPME) injector heads. The use of two SPME fibers significantly reduces sample analysis cycle times making this method very suitable for high sample throughput, which is a requirement for large public health biomonitoring studies. Our sample preparation procedure involved solubilization of blood samples with tetramethylammonium hydroxide (TMAH) followed by the derivatization with sodium tetra(n-propyl)borate (NaBPr(4)) to promote volatility of mercury species. We thoroughly investigated mercury species stability in the blood matrix during the course of sample treatment and analysis. The method accuracy for quantifying iHg, MeHg, and EtHg was validated using NIST standard reference materials (SRM 955c level 3) and the Centre de Toxicologie du Québec (CTQ) proficiency testing (PT) samples. The limit of detection (LOD) for iHg, MeHg, and EtHg in human blood was determined to be 0.27, 0.12, and 0.16 μg/L, respectively. JF - Analytical and bioanalytical chemistry AU - Sommer, Yuliya L AU - Verdon, Carl P AU - Fresquez, Mark R AU - Ward, Cynthia D AU - Wood, Elliott B AU - Pan, Yi AU - Caldwell, Kathleen L AU - Jones, Robert L AD - Centers for Disease Control and Prevention, National Center for Environmental Health, Division of Analytical Sciences, Inorganic and Radiation Analytical Toxicology Branch, 4770 Buford Highway, N.E., MS F-50, Atlanta, GA, 30341, USA, YSommer@cdc.gov. Y1 - 2014/08// PY - 2014 DA - August 2014 SP - 5039 EP - 5047 VL - 406 IS - 20 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1545416124?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytical+and+bioanalytical+chemistry&rft.atitle=Measurement+of+mercury+species+in+human+blood+using+triple+spike+isotope+dilution+with+SPME-GC-ICP-DRC-MS.&rft.au=Sommer%2C+Yuliya+L%3BVerdon%2C+Carl+P%3BFresquez%2C+Mark+R%3BWard%2C+Cynthia+D%3BWood%2C+Elliott+B%3BPan%2C+Yi%3BCaldwell%2C+Kathleen+L%3BJones%2C+Robert+L&rft.aulast=Sommer&rft.aufirst=Yuliya&rft.date=2014-08-01&rft.volume=406&rft.issue=20&rft.spage=5039&rft.isbn=&rft.btitle=&rft.title=Analytical+and+bioanalytical+chemistry&rft.issn=1618-2650&rft_id=info:doi/10.1007%2Fs00216-014-7907-4 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2015-05-21 N1 - Date created - 2014-07-15 N1 - Date revised - 2017-01-14 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1007/s00216-014-7907-4 ER - TY - JOUR T1 - Yersinia enterocolitica infections associated with improperly pasteurized milk products: southwest Pennsylvania, March-August, 2011. AN - 1536685712; 24128938 AB - In July 2011, a cluster of Yersinia enterocolitica infections was detected in southwestern Pennsylvania, USA. We investigated the outbreak's source and scope in order to prevent further transmission. Twenty-two persons were diagnosed with yersiniosis; 16 of whom reported consuming pasteurized dairy products from dairy A. Pasteurized milk and food samples were collected from this dairy. Y. enterocolitica was isolated from two products. Isolates from both food samples and available clinical isolates from nine dairy A consumers were indistinguishable by pulsed-field gel electrophoresis. Environmental and microbiological investigations were performed at dairy A and pasteurization deficiencies were noted. Because consumption of pasteurized milk is common and outbreaks have the potential to become large, public health interventions such as consumer advisories or closure of the dairy must be implemented quickly to prevent additional cases if epidemiological or laboratory evidence implicates pasteurized milk as the outbreak source. JF - Epidemiology and infection AU - Longenberger, A H AU - Gronostaj, M P AU - Yee, G Y AU - Johnson, L M AU - Lando, J F AU - Voorhees, R E AU - Waller, K AU - Weltman, A C AU - Moll, M AU - Lyss, S B AU - Cadwell, B L AU - Gladney, L M AU - Ostroff, S M AD - Epidemic Intelligence Service; Scientific Education and Professional Development Program Office; Office of Surveillance, Epidemiology, and Laboratory Services; Centers for Disease Control and Prevention, Atlanta, GA,USA. ; Allegheny County Health Department, Pittsburgh, PA,USA. ; Pennsylvania Department of Agriculture, Harrisburg, PA,USA. ; Pennsylvania Department of Health, Harrisburg, PA,USA. ; Scientific Education and Professional Development Program Office; Office of Surveillance, Epidemiology, and Laboratory Services; Centers for Disease Control and Prevention, Atlanta, GA,USA. ; National Center for Emerging and Zoonotic Infectious Diseases, Division of Foodborne, Waterborne and Environmental Diseases, Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA,USA. Y1 - 2014/08// PY - 2014 DA - August 2014 SP - 1640 EP - 1650 VL - 142 IS - 8 KW - Index Medicus KW - Molecular Typing KW - Young Adult KW - Animals KW - Humans KW - Aged KW - Child KW - Child, Preschool KW - Genotype KW - Infant KW - Adult KW - Cohort Studies KW - Electrophoresis, Gel, Pulsed-Field KW - Middle Aged KW - Pennsylvania -- epidemiology KW - Adolescent KW - Male KW - Female KW - Yersinia Infections -- epidemiology KW - Foodborne Diseases -- epidemiology KW - Milk -- microbiology KW - Foodborne Diseases -- microbiology KW - Yersinia enterocolitica -- genetics KW - Yersinia enterocolitica -- classification KW - Yersinia enterocolitica -- isolation & purification KW - Yersinia Infections -- microbiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1536685712?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+infection&rft.atitle=Yersinia+enterocolitica+infections+associated+with+improperly+pasteurized+milk+products%3A+southwest+Pennsylvania%2C+March-August%2C+2011.&rft.au=Longenberger%2C+A+H%3BGronostaj%2C+M+P%3BYee%2C+G+Y%3BJohnson%2C+L+M%3BLando%2C+J+F%3BVoorhees%2C+R+E%3BWaller%2C+K%3BWeltman%2C+A+C%3BMoll%2C+M%3BLyss%2C+S+B%3BCadwell%2C+B+L%3BGladney%2C+L+M%3BOstroff%2C+S+M&rft.aulast=Longenberger&rft.aufirst=A&rft.date=2014-08-01&rft.volume=142&rft.issue=8&rft.spage=1640&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+infection&rft.issn=1469-4409&rft_id=info:doi/10.1017%2FS0950268813002616 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2014-08-01 N1 - Date created - 2014-06-16 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1017/S0950268813002616 ER - TY - JOUR T1 - Detection of Bacterial Agents in Amblyomma americanum (Acari: Ixodidae) from Georgia, USA, and the use of a Multiplex Assay to Differentiate Ehrlichia chaffeensis and Ehrlichia ewingii AN - 1547849297; 20281484 AB - Amblyomma americanum, the lone star tick, is the most common and most aggressive human biting tick in the Southeastern United States. It is known to transmit the agents of human ehrlichioses, Ehrlichia chaffeensis and Ehrlichia ewingii. In addition, it carries agents of unspecified pathogenicity to humans, including Rickettsia amblyommii, Borrelia lonestari, and the newly emerging Panola Mountain Ehrlichia (PME). Surveillance of these ticks for recognized or emerging pathogens is necessary for assessing the risk of human infection. From 2005 to 2009, we surveyed A. americanum ticks from four locations in the state of Georgia. Ticks (1,183 adults, 2,954 nymphs, and 99 larval batches) were tested using a multiplex real-time polymerase chain reaction (PCR) assay designed to detect and discriminate DNA from Rickettsia spp., E. chaffeensis, and E. ewingii, This assay was capable of detecting as few as 10 gene copies of the aforementioned agents. Ticks were also tested for PME and B. lonestari by nested PCR. The prevalence of infection ranged from 0 to 2.5% for E. chaffeensis, 0 to 3.9% for E. ewingii, 0 to 2.2% for PME, 17 to 83.1% for R. amblyommii, and 0 to 3.1% for B. lonestari. There were 46 (4.1%) individual adults positive for two agents, and two females that were each positive for three agents. Two larval batches were positive for both B. lonestari and R. amblyommii, indicating the potential for transovarial transmission of both agents from a single female. Although infrequent in occurrence, the dynamics of coinfections in individual ticks should be explored further, given the potential implications for differential diagnosis and severity of human illness. JF - Journal of Medical Entomology AU - Killmaster, L F AU - Loftis, AD AU - Zemtsova, GE AU - Levin, M L AD - Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA 30333, MLevin@cdc.gov Y1 - 2014/07// PY - 2014 DA - Jul 2014 SP - 868 EP - 872 PB - Entomological Society of America, 9301 Annapolis Rd. Lanham MD 20706 United States VL - 51 IS - 4 SN - 0022-2585, 0022-2585 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology; Entomology Abstracts KW - Amblyomma americanum KW - multiplex KW - Ehrlichia KW - Rickettsia KW - Borrelia KW - Bacteria KW - Ixodidae KW - Pathogens KW - Infection KW - Mountains KW - Differential diagnosis KW - Biting KW - Pathogenicity KW - Ehrlichia ewingii KW - Polymerase chain reaction KW - Ehrlichia chaffeensis KW - Acari KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - J 02400:Human Diseases KW - A 01300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1547849297?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Medical+Entomology&rft.atitle=Detection+of+Bacterial+Agents+in+Amblyomma+americanum+%28Acari%3A+Ixodidae%29+from+Georgia%2C+USA%2C+and+the+use+of+a+Multiplex+Assay+to+Differentiate+Ehrlichia+chaffeensis+and+Ehrlichia+ewingii&rft.au=Killmaster%2C+L+F%3BLoftis%2C+AD%3BZemtsova%2C+GE%3BLevin%2C+M+L&rft.aulast=Killmaster&rft.aufirst=L&rft.date=2014-07-01&rft.volume=51&rft.issue=4&rft.spage=868&rft.isbn=&rft.btitle=&rft.title=Journal+of+Medical+Entomology&rft.issn=00222585&rft_id=info:doi/10.1603%2FME12233 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-07-01 N1 - Number of references - 23 N1 - Last updated - 2015-08-05 N1 - SubjectsTermNotLitGenreText - Mountains; Differential diagnosis; Pathogenicity; Biting; Polymerase chain reaction; Pathogens; Infection; Amblyomma americanum; Bacteria; Ehrlichia ewingii; Ixodidae; Rickettsia; Borrelia; Ehrlichia chaffeensis; Acari DO - http://dx.doi.org/10.1603/ME12233 ER - TY - JOUR T1 - Estimating per-act HIV transmission risk: a systematic review AN - 1765969864; PQ0002559439 AB - Background: Effective HIV prevention programs rely on accurate estimates of the per-act risk of HIV acquisition from sexual and parenteral exposures. We updated the previous risk estimates of HIV acquisition from parenteral, vertical, and sexual exposures, and assessed the modifying effects of factors including condom use, male circumcision, and antiretroviral therapy. Methods: We conducted literature searches to identify new studies reporting data regarding per-act HIV transmission risk and modifying factors. Of the 7339 abstracts potentially related to per-act HIV transmission risk, three meta-analyses provided pooled per-act transmission risk probabilities and two studies provided data on modifying factors. Of the 8119 abstracts related to modifying factors, 15 relevant articles, including three meta-analyses, were included. We used fixed-effects inverse-variance models on the logarithmic scale to obtain updated estimates of certain transmission risks using data from primary studies, and employed Poisson regression to calculate relative risks with exact 95% confidence intervals for certain modifying factors. Results: Risk of HIV transmission was greatest for blood transfusion, followed by vertical exposure, sexual exposures, and other parenteral exposures. Sexual exposure risks ranged from low for oral sex to 138 infections per 10 000 exposures for receptive anal intercourse. Estimated risks of HIV acquisition from sexual exposure were attenuated by 99.2% with the dual use of condoms and antiretroviral treatment of the HIV-infected partner. Conclusion: The risk of HIV acquisition varied widely, and the estimates for receptive anal intercourse increased compared with previous estimates. The risk associated with sexual intercourse was reduced most substantially by the combined use of condoms and antiretroviral treatment of HIV-infected partners. JF - AIDS AU - Patel, Pragna AU - Borkowf, Craig B AU - Brooks, John T AU - Lasry, Arielle AU - Lansky, Amy AU - Mermin, Jonathan AD - Division of HIV/AIDS Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, plp3@cdc.gov Y1 - 2014/06/19/ PY - 2014 DA - 2014 Jun 19 SP - 1509 EP - 1519 PB - Lippincott Williams & Wilkins, Inc, 530 Walnut Street Philadelphia PA 19106-3621 United States VL - 28 IS - 10 SN - 0269-9370, 0269-9370 KW - Health & Safety Science Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - HIV KW - per-act KW - prevention KW - risk KW - transmission KW - Risk assessment KW - Acquired immune deficiency syndrome KW - Anal sex KW - Transfusion KW - Infection KW - Sexual behavior KW - Models KW - Disease transmission KW - Condoms KW - Antiviral agents KW - Risk factors KW - Regression analysis KW - Sexual intercourse KW - Sex KW - Data processing KW - antiretroviral therapy KW - Antiretroviral agents KW - Prevention KW - Blood transfusion KW - Human immunodeficiency virus KW - Reviews KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1765969864?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS&rft.atitle=Estimating+per-act+HIV+transmission+risk%3A+a+systematic+review&rft.au=Patel%2C+Pragna%3BBorkowf%2C+Craig+B%3BBrooks%2C+John+T%3BLasry%2C+Arielle%3BLansky%2C+Amy%3BMermin%2C+Jonathan&rft.aulast=Patel&rft.aufirst=Pragna&rft.date=2014-06-19&rft.volume=28&rft.issue=10&rft.spage=1509&rft.isbn=&rft.btitle=&rft.title=AIDS&rft.issn=02699370&rft_id=info:doi/10.1097%2FQAD.0000000000000298 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Risk assessment; Data processing; antiretroviral therapy; Infection; Disease transmission; Models; Condoms; Blood transfusion; Antiviral agents; Reviews; Risk factors; Regression analysis; Sexual intercourse; Sex; Acquired immune deficiency syndrome; Anal sex; Transfusion; Antiretroviral agents; Sexual behavior; Prevention; Human immunodeficiency virus DO - http://dx.doi.org/10.1097/QAD.0000000000000298 ER - TY - JOUR T1 - HIV sexual transmission risk among serodiscordant couples: assessing the effects of combining prevention strategies AN - 1765969012; PQ0002559440 AB - Background: The number of strategies to prevent HIV transmission has increased following trials evaluating antiretroviral therapy (ART), preexposure prophylaxis (PrEP) and male circumcision. Serodiscordant couples need guidance on the effects of these strategies alone, and in combination with each other, on HIV transmission. Methods: We estimated the sexual risk of HIV transmission over 1-year and 10-year periods among male-male and male-female serodiscordant couples. We assumed the following reductions in transmission: 80% from consistent condom use; 54% from circumcision in the negative male partner of a heterosexual couple; 73% from circumcision in the negative partner of a male-male couple; 71% from PrEP in heterosexual couples; 44% from PrEP in male-male couples; and 96% from ART use by the HIV-infected partner. Findings: For couples using any single prevention strategy, a substantial cumulative risk of HIV transmission remained. For a male-female couple using only condoms, estimated risk over 10 years was 11%; for a male-male couple using only condoms, estimated risk was 76%. ART use by the HIV-infected partner was the most effective single strategy in reducing risk; among male-male couples, adding consistent condom use was necessary to keep the 10-year risk below 10%. Conclusion: Focusing on 1-year and longer term transmission probabilities gives couples a better understanding of risk than those illustrated by data for a single sexual act. Long-term transmission probabilities to the negative partner in serodiscordant couples can be high, though these can be substantially reduced with the strategic use of preventive methods, especially those that include ART. JF - AIDS AU - Lasry, Arielle AU - Sansom, Stephanie L AU - Wolitski, Richard J AU - Green, Timothy A AU - Borkowf, Craig B AU - Patel, Pragna AU - Mermin, Jonathan AD - Division of HIV/AIDS Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, alasry@cdc.gov Y1 - 2014/06/19/ PY - 2014 DA - 2014 Jun 19 SP - 1521 EP - 1529 PB - Lippincott Williams & Wilkins, Inc, 530 Walnut Street Philadelphia PA 19106-3621 United States VL - 28 IS - 10 SN - 0269-9370, 0269-9370 KW - Health & Safety Science Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - acquisition KW - antiretroviral therapy KW - circumcision KW - condom KW - HIV KW - preexposure prophylaxis KW - serodiscordant couple KW - transmission KW - Risk assessment KW - Acquired immune deficiency syndrome KW - Data processing KW - Risk reduction KW - Antiretroviral agents KW - Disease transmission KW - Condoms KW - Prevention KW - Human immunodeficiency virus KW - Prophylaxis KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1765969012?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS&rft.atitle=HIV+sexual+transmission+risk+among+serodiscordant+couples%3A+assessing+the+effects+of+combining+prevention+strategies&rft.au=Lasry%2C+Arielle%3BSansom%2C+Stephanie+L%3BWolitski%2C+Richard+J%3BGreen%2C+Timothy+A%3BBorkowf%2C+Craig+B%3BPatel%2C+Pragna%3BMermin%2C+Jonathan&rft.aulast=Lasry&rft.aufirst=Arielle&rft.date=2014-06-19&rft.volume=28&rft.issue=10&rft.spage=1521&rft.isbn=&rft.btitle=&rft.title=AIDS&rft.issn=02699370&rft_id=info:doi/10.1097%2FQAD.0000000000000307 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Condoms; Data processing; antiretroviral therapy; Prophylaxis; Disease transmission; Risk assessment; Acquired immune deficiency syndrome; Prevention; Human immunodeficiency virus; Risk reduction; Antiretroviral agents DO - http://dx.doi.org/10.1097/QAD.0000000000000307 ER - TY - JOUR T1 - The role of nodose ganglia in the regulation of cardiovascular function following pulmonary exposure to ultrafine titanium dioxide AN - 1639474012; 21120921 AB - The inhalation of nanosized air pollutant particles is a recognised risk factor for cardiovascular disease; however, the link between occupational exposure to engineered nanoparticles and adverse cardiovascular events remains unclear. In the present study, the authors demonstrated that pulmonary exposure of rats to ultrafine titanium dioxide (UFTiO sub(2)2) significantly increased heart rate and depressed diastolic function of the heart in response to isoproterenol. Moreover, pulmonary inhalation of UFTiO sub(2)2 elevated mean and diastolic blood pressure in response to norepinephrine. Pretreatment of the rats ip with the transient receptor potential (TRP) channel blocker ruthenium red inhibited substance P synthesis in nodose ganglia and associated functional and biological changes in the cardiovascular system. In conclusion, the effects of pulmonary inhalation of UFTiO sub(2)2 on cardiovascular function are most likely triggered by a lungnodose ganglia-regulated pathway via the activation of TRP channels in the lung. JF - Nanotoxicology AU - Kan, Hong AU - Wu, Zhongxin AU - Lin, Yen-Chang AU - Chen, Teh-Hsun AU - Cumpston, Jared L AU - Kashon, Michael L AU - Leonard, Steve AU - Munson, Albert E AU - Castranova, Vincent AD - Hong Kan, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, PPRB, 1095 Willowdale Road, Morgantown, WV 26505, USA, hvn4@cdc.gov Y1 - 2014/06// PY - 2014 DA - Jun 2014 SP - 447 EP - 454 PB - Informa Healthcare, 52 Vanderbilt Ave. New York New York 10017 USA VL - 8 IS - 4 SN - 1743-5390, 1743-5390 KW - Pollution Abstracts; Health & Safety Science Abstracts; Risk Abstracts; Toxicology Abstracts KW - nanoparticles KW - neural pathways KW - cardiovascular system KW - inhalation study KW - Inhalation KW - Cardiovascular system KW - Heart rate KW - Particulates KW - Blood pressure KW - Rats KW - Titanium dioxide KW - Pollutants KW - Risk factors KW - Nodose ganglion KW - transient receptor potential proteins KW - Occupational exposure KW - Ruthenium red KW - Ruthenium KW - Substance P KW - Air pollution KW - Lung KW - Norepinephrine KW - isoproterenol KW - Cardiovascular diseases KW - X 24310:Pharmaceuticals KW - P 0000:AIR POLLUTION KW - H 1000:Occupational Safety and Health KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1639474012?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Nanotoxicology&rft.atitle=The+role+of+nodose+ganglia+in+the+regulation+of+cardiovascular+function+following+pulmonary+exposure+to+ultrafine+titanium+dioxide&rft.au=Kan%2C+Hong%3BWu%2C+Zhongxin%3BLin%2C+Yen-Chang%3BChen%2C+Teh-Hsun%3BCumpston%2C+Jared+L%3BKashon%2C+Michael+L%3BLeonard%2C+Steve%3BMunson%2C+Albert+E%3BCastranova%2C+Vincent&rft.aulast=Kan&rft.aufirst=Hong&rft.date=2014-06-01&rft.volume=8&rft.issue=4&rft.spage=447&rft.isbn=&rft.btitle=&rft.title=Nanotoxicology&rft.issn=17435390&rft_id=info:doi/10.3109%2F17435390.2013.796536 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-12-01 N1 - Last updated - 2015-05-13 N1 - SubjectsTermNotLitGenreText - Inhalation; Ruthenium red; Cardiovascular system; Heart rate; Substance P; Blood pressure; Titanium dioxide; Pollutants; Lung; Risk factors; Norepinephrine; Nodose ganglion; isoproterenol; Cardiovascular diseases; transient receptor potential proteins; nanoparticles; Occupational exposure; Ruthenium; Particulates; Rats; Air pollution DO - http://dx.doi.org/10.3109/17435390.2013.796536 ER - TY - JOUR T1 - Physical Assaults Among Education Workers: Findings From a Statewide Study AN - 1560115271; 20469197 AB - Objective: Enumerate and describe physical assaults occurring to Pennsylvania education workers. Methods: A cross-sectional survey was mailed to a random sample of 6450 workers, stratified on gender, occupation, and region. Logistic regression was used to examine risk factors for physical assault. Results: During the 2009-2010 school year, 309 of 2514 workers were assaulted 597 times. Special education teachers, urban workers, and those in their first 3 years of employment were at an increased risk. Most assaults did not lead to medical care or time away from work; however, those assaulted were significantly more likely to find work stressful, have low job satisfaction, and consider leaving the education field (adjusted odds ratio [AOR] = 2.5 [95% CI = 1.5 to 4.1]; AOR = 2.4 [95% CI = 1.5 to 3.9]; AOR = 10.7 [95% CI = 4.1 to 28.1]). Conclusions: Although education workers experienced few serious physical assaults, the impact of this violence was considerable. JF - Journal of Occupational and Environmental Medicine AU - Tiesman, Hope M AU - Hendricks, Scott AU - Konda, Srinivas AU - Hartley, Dan AD - National Institute for Occupational Safety and Health, Division of Safety Research, Analysis and Field Evaluations Branch, 1095 Willowdale Rd, M/S 1811, Morgantown, WV 26506, htiesman@cdc.gov PY - 2014 SP - 621 EP - 627 PB - Williams & Wilkins, 351 W. Camden St. Baltimore MD 21201 United States VL - 56 IS - 6 SN - 1076-2752, 1076-2752 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Education KW - Schools KW - Risk factors KW - USA, Pennsylvania KW - Gender KW - Employment KW - Violence KW - H 1000:Occupational Safety and Health KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1560115271?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Physical+Assaults+Among+Education+Workers%3A+Findings+From+a+Statewide+Study&rft.au=Tiesman%2C+Hope+M%3BHendricks%2C+Scott%3BKonda%2C+Srinivas%3BHartley%2C+Dan&rft.aulast=Tiesman&rft.aufirst=Hope&rft.date=2014-06-01&rft.volume=56&rft.issue=6&rft.spage=621&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0000000000000147 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Last updated - 2015-12-23 N1 - SubjectsTermNotLitGenreText - Education; Schools; Risk factors; Gender; Employment; Violence; USA, Pennsylvania DO - http://dx.doi.org/10.1097/JOM.0000000000000147 ER - TY - JOUR T1 - Metropolitan Racial Residential Segregation and Cardiovascular Mortality: Exploring Pathways AN - 1554942781; 20483518 AB - Racial residential segregation has been associated with an increased risk for heart disease and stroke deaths. However, there has been little research into the role that candidate mediating pathways may play in the relationship between segregation and heart disease or stroke deaths. In this study, we examined the relationship between metropolitan statistical area (MSA)-level segregation and heart disease and stroke mortality rates, by age and race, and also estimated the effects of various educational, economic, social, and health-care indicators (which we refer to as pathways) on this relationship. We used Poisson mixed models to assess the relationship between the isolation index in 265 U.S. MSAs and county-level (heart disease, stroke) mortality rates. All models were stratified by race (non-Hispanic black, non-Hispanic white), age group (35-64 years, greater than or equal to 65 years), and cause of death (heart disease, stroke). We included each potential pathway in the model separately to evaluate its effect on the segregation-mortality association. Among blacks, segregation was positively associated with heart disease mortality rates in both age groups but only with stroke mortality rates in the older age group. Among whites, segregation was marginally associated with heart disease mortality rates in the younger age group and was positively associated with heart disease mortality rates in the older age group. Three of the potential pathways we explored attenuated relationships between segregation and mortality rates among both blacks and whites: percentage of female-headed households, percentage of residents living in poverty, and median household income. Because the percentage of female-headed households can be seen as a proxy for the extent of social disorganization, our finding that it has the greatest attenuating effect on the relationship between racial segregation and heart disease and stroke mortality rates suggests that social disorganization may play a strong role in the elevated rates of heart disease and stroke found in racially segregated metropolitan areas. JF - Journal of Urban Health AU - Greer, Sophia AU - Kramer, Michael R AU - Cook-Smith, Jessica N AU - Casper, Michele L AD - Division for Heart Disease and Stroke Prevention, Centers for Disease Control and Prevention, 4770 Buford Hwy, NE, MS F-72, Atlanta, GA, 30341, USA, sgreer@cdc.gov Y1 - 2014/06// PY - 2014 DA - Jun 2014 SP - 499 EP - 509 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 91 IS - 3 SN - 1099-3460, 1099-3460 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Risk assessment KW - Mortality KW - Age KW - Stroke KW - Income KW - Social disorganization KW - Households KW - Poverty KW - Economics KW - Age groups KW - Metropolitan areas KW - Heart diseases KW - R2 23060:Medical and environmental health KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1554942781?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Urban+Health&rft.atitle=Metropolitan+Racial+Residential+Segregation+and+Cardiovascular+Mortality%3A+Exploring+Pathways&rft.au=Greer%2C+Sophia%3BKramer%2C+Michael+R%3BCook-Smith%2C+Jessica+N%3BCasper%2C+Michele+L&rft.aulast=Greer&rft.aufirst=Sophia&rft.date=2014-06-01&rft.volume=91&rft.issue=3&rft.spage=499&rft.isbn=&rft.btitle=&rft.title=Journal+of+Urban+Health&rft.issn=10993460&rft_id=info:doi/10.1007%2Fs11524-013-9834-7 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-08-01 N1 - Number of references - 32 N1 - Last updated - 2014-10-02 N1 - SubjectsTermNotLitGenreText - Risk assessment; Mortality; Age; Social disorganization; Poverty; Households; Economics; Stroke; Age groups; Metropolitan areas; Income; Heart diseases DO - http://dx.doi.org/10.1007/s11524-013-9834-7 ER - TY - JOUR T1 - Analytical considerations in the clinical laboratory assessment of metals. AN - 1535630388; 24515525 AB - The presence of metals in the environment is ubiquitous and humans are constantly being exposed to them. As such, a general concern exists about potential health consequences that result from the exposure to metals. The continued efforts of environmental scientists to measure metals in clinical specimens are important for defining the extent of human exposure to these chemicals. Laboratory methods to measure the concentration of metals in human blood or urine are available, and they can be used to assess the extent of human exposure to these chemicals. However, several considerations should be reviewed when requesting a laboratory measurement of metals because some factors can affect the test result or its interpretation. These considerations are discussed in this article and include pre-analytical, analytical, and post-analytical factors. Clinicians with this knowledge will be able to request these laboratory tests for their patients with enhanced confidence. JF - Journal of medical toxicology : official journal of the American College of Medical Toxicology AU - Wang, Richard Y AU - Caldwell, Kathleen L AU - Jones, Robert L AD - Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway, Atlanta, GA, 30341, USA, rywang@cdc.gov. Y1 - 2014/06// PY - 2014 DA - June 2014 SP - 232 EP - 239 VL - 10 IS - 2 KW - Metals KW - 0 KW - Index Medicus KW - Reference Values KW - Centers for Disease Control and Prevention (U.S.) KW - Humans KW - Toxicology -- methods KW - Nutrition Surveys KW - Epidemiological Monitoring KW - Congresses as Topic KW - United States -- epidemiology KW - Environmental Monitoring -- methods KW - Prevalence KW - Metals -- blood KW - Poisoning -- urine KW - Poisoning -- epidemiology KW - Environmental Exposure -- adverse effects KW - Metals -- analysis KW - Poisoning -- blood KW - Metals -- urine KW - Metals -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1535630388?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+medical+toxicology+%3A+official+journal+of+the+American+College+of+Medical+Toxicology&rft.atitle=Analytical+considerations+in+the+clinical+laboratory+assessment+of+metals.&rft.au=Wang%2C+Richard+Y%3BCaldwell%2C+Kathleen+L%3BJones%2C+Robert+L&rft.aulast=Wang&rft.aufirst=Richard&rft.date=2014-06-01&rft.volume=10&rft.issue=2&rft.spage=232&rft.isbn=&rft.btitle=&rft.title=Journal+of+medical+toxicology+%3A+official+journal+of+the+American+College+of+Medical+Toxicology&rft.issn=1937-6995&rft_id=info:doi/10.1007%2Fs13181-014-0381-8 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2015-02-12 N1 - Date created - 2014-06-14 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Cited By: Clin Chem Lab Med. 2004;42(7):692-7 [15327001] Arch Environ Health. 1970 Dec;21(6):717-27 [5478557] Clin Chem. 1970 Dec;16(12):1016-21 [5481561] Clin Chem. 1970 Dec;16(12):1022-7 [5481562] Clin Chem. 1974 Dec;20(12):1535-42 [4430131] Clin Chem. 1983 Jan;29(1):25-30 [6848276] J Clin Chem Clin Biochem. 1983 Nov;21(11):749-60 [6655449] Ann Clin Biochem. 1988 May;25 ( Pt 3):259-63 [3400982] Toxicol Pathol. 1988;16(2):147-53 [3055224] Crit Rev Clin Lab Sci. 1989;27(5):409-37 [2679660] MMWR Morb Mortal Wkly Rep. 1991 Jun 14;40(23):393-5 [2041541] MMWR Morb Mortal Wkly Rep. 1994 Aug 5;43(30):545-8 [8035771] J Pharmacol Exp Ther. 1996 Apr;277(1):239-44 [8613926] Am J Ind Med. 2007 Oct;50(10):757-64 [17477364] Am J Clin Nutr. 2007 Oct;86(4):1202-9 [17921403] Anal Chem. 2008 Feb 15;80(4):1124-32 [18197633] J Expo Sci Environ Epidemiol. 2009 Jan;19(1):59-68 [18523458] Natl Health Stat Report. 2010 Mar 1;(21):1-7 [20540274] J Forensic Sci. 2010 Jul;55(4):1116-9 [20384929] Environ Health Perspect. 2012 Apr;120(4):601-7 [22186192] J Med Toxicol. 2013 Mar;9(1):9-15 [23143832] MMWR Morb Mortal Wkly Rep. 2013 Apr 5;62(13):245-8 [23552225] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1007/s13181-014-0381-8 ER - TY - JOUR T1 - Unintentional injury mortality among American Indians and Alaska Natives in the United States, 1990-2009. AN - 1525769353; 24754624 AB - We describe the burden of unintentional injury (UI) deaths among American Indian and Alaska Native (AI/AN) populations in the United States. National Death Index records for 1990 to 2009 were linked with Indian Health Service registration records to identify AI/AN deaths misclassified as non-AI/AN deaths. Most analyses were restricted to Contract Health Service Delivery Area counties in 6 geographic regions of the United States. We compared age-adjusted death rates for AI/AN persons with those for Whites; Hispanics were excluded. From 2005 to 2009, the UI death rate for AI/AN people was 2.4 times higher than for Whites. Death rates for the 3 leading causes of UI death-motor vehicle traffic crashes, poisoning, and falls-were 1.4 to 3 times higher among AI/AN persons than among Whites. UI death rates were higher among AI/AN males than among females and highest among AI/AN persons in Alaska, the Northern Plains, and the Southwest. AI/AN persons had consistently higher UI death rates than did Whites. This disparity in overall rates coupled with recent increases in unintentional poisoning deaths requires that injury prevention be a major priority for improving health and preventing death among AI/AN populations. JF - American journal of public health AU - Murphy, Tierney AU - Pokhrel, Pallavi AU - Worthington, Anne AU - Billie, Holly AU - Sewell, Mack AU - Bill, Nancy AD - Tierney Murphy, Pallavi Pokhrel, and Anne Worthington are with the Epidemiology and Response Division, New Mexico Department of Health, Santa Fe. Holly Billie is with the National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA. Mack Sewell is with the Wyoming Department of Workforce Services, Cheyenne. Nancy Bill is with Indian Health Services, Rockville, MD. Y1 - 2014/06// PY - 2014 DA - June 2014 SP - S470 EP - S480 VL - 104 Suppl 3 KW - Abridged Index Medicus KW - Index Medicus KW - Alaska -- ethnology KW - Humans KW - Alaska -- epidemiology KW - Infant, Newborn KW - Aged KW - European Continental Ancestry Group -- statistics & numerical data KW - Child KW - Cause of Death KW - Population Surveillance KW - Child, Preschool KW - Registries KW - Infant KW - Aged, 80 and over KW - Adult KW - Death Certificates KW - Middle Aged KW - Adolescent KW - United States -- epidemiology KW - Male KW - Female KW - Inuits -- statistics & numerical data KW - Indians, North American -- statistics & numerical data KW - Wounds and Injuries -- mortality KW - Wounds and Injuries -- ethnology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1525769353?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+journal+of+public+health&rft.atitle=Unintentional+injury+mortality+among+American+Indians+and+Alaska+Natives+in+the+United+States%2C+1990-2009.&rft.au=Murphy%2C+Tierney%3BPokhrel%2C+Pallavi%3BWorthington%2C+Anne%3BBillie%2C+Holly%3BSewell%2C+Mack%3BBill%2C+Nancy&rft.aulast=Murphy&rft.aufirst=Tierney&rft.date=2014-06-01&rft.volume=104+Suppl+3&rft.issue=&rft.spage=S470&rft.isbn=&rft.btitle=&rft.title=American+journal+of+public+health&rft.issn=1541-0048&rft_id=info:doi/10.2105%2FAJPH.2013.301854 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2014-07-03 N1 - Date created - 2014-05-16 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Cited By: MMWR Surveill Summ. 2011 May 6;60(5):1-32 [21544045] J Am Geriatr Soc. 2011 Jan;59(1):148-57 [21226685] Epidemiol Rev. 2012;34:73-88 [22088912] MMWR Morb Mortal Wkly Rep. 2012 Apr 20;61:270-6 [22513530] J Safety Res. 2012 Sep;43(4):283-9 [23127678] Cancer. 2014 May 1;120(9):1290-314 [24343171] Am J Public Health. 2014 Jun;104 Suppl 3:S286-94 [24754557] Am J Public Health. 2014 Jun;104 Suppl 3:S343-9 [24754661] Vital Health Stat 2. 1999 Sep;(128):1-13 [10611854] MMWR Morb Mortal Wkly Rep. 2002 Apr 12;51(14):303-5 [12002169] Public Health Rep. 2002 Jan-Feb;117(1):44-9 [12297681] MMWR Recomm Rep. 2001 May 18;50(RR-7):1-14 [12418509] Inj Prev. 2002 Dec;8(4):289-92 [12460964] Gerontologist. 1994 Feb;34(1):16-23 [8150304] Natl Vital Stat Rep. 2006 Jan 31;54(10):1-124 [16485447] Am J Public Health. 2006 Aug;96(8):1478-84 [16571711] Stat Methods Med Res. 2006 Dec;15(6):547-69 [17260923] Crit Care Nurs Q. 2008 Jan-Mar;31(1):40-5 [18316935] MMWR Morb Mortal Wkly Rep. 2008 Aug 29;57(34):938-41 [18756193] Matern Child Health J. 2008 Jul;12 Suppl 1:55-63 [18340516] Am J Prev Med. 2009 Sep;37(3):188-94 [19595555] Stat Med. 2009 Dec 20;28(29):3670-82 [19856324] MMWR Morb Mortal Wkly Rep. 2011 Nov 4;60(43):1487-92 [22048730] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.2105/AJPH.2013.301854 ER - TY - JOUR T1 - Acinetobacter bacteraemia in Thailand: evidence for infections outside the hospital setting AN - 1524410868; 19787184 AB - Acinetobacter is a well-recognized nosocomial pathogen. Previous reports of community-associated Acinetobacter infections have lacked clear case definitions and assessment of healthcare-associated (HCA) risk factors. We identified Acinetobacter bacteraemia cases from blood cultures obtained <3 days after hospitalization in rural Thailand and performed medical record reviews to assess HCA risk factors in the previous year and compare clinical and microbiological characteristics between cases with and without HCA risk factors. Of 72 Acinetobacter cases, 32 (44%) had no HCA risk factors. Compared to HCA infections, non-HCA infections were more often caused by Acinetobacter species other than calcoaceticus-baumannii complex species and by antibiotic-susceptible organisms. Despite similar symptoms, the case-fatality proportion was lower in non-HCA than HCA cases (9% vs. 45%, P < 0.01). Clinicians should be aware of Acinetobacter as a potential cause of community-associated infections in Thailand; prospective studies are needed to improve understanding of associated risk factors and disease burden. JF - Epidemiology and Infection AU - Porter, Ka AU - Rhodes, J AU - DEJSIRILERT, S AU - HENCHAICHON, S AU - SILUDJAI, D AU - THAMTHITIWAT, S AU - PRAPASIRI, P AU - JORAKATE, P AU - KAEWPAN, A AU - Peruski, L F AU - KERDSIN, A AU - PRASERT, K AU - YUENPRAKONE, S AU - Maloney, Sa AU - Baggett, H C AD - Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA, kaporter@cdc.gov Y1 - 2014/06// PY - 2014 DA - June 2014 SP - 1317 EP - 1327 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 142 IS - 6 SN - 0950-2688, 0950-2688 KW - Microbiology Abstracts B: Bacteriology; Risk Abstracts KW - Blood culture KW - medical records KW - Thailand KW - Bacteremia KW - Pathogens KW - Infection KW - Acinetobacter KW - Reviews KW - Risk factors KW - Rural areas KW - Hospitals KW - J 02400:Human Diseases KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1524410868?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Acinetobacter+bacteraemia+in+Thailand%3A+evidence+for+infections+outside+the+hospital+setting&rft.au=Porter%2C+Ka%3BRhodes%2C+J%3BDEJSIRILERT%2C+S%3BHENCHAICHON%2C+S%3BSILUDJAI%2C+D%3BTHAMTHITIWAT%2C+S%3BPRAPASIRI%2C+P%3BJORAKATE%2C+P%3BKAEWPAN%2C+A%3BPeruski%2C+L+F%3BKERDSIN%2C+A%3BPRASERT%2C+K%3BYUENPRAKONE%2C+S%3BMaloney%2C+Sa%3BBaggett%2C+H+C&rft.aulast=Porter&rft.aufirst=Ka&rft.date=2014-06-01&rft.volume=142&rft.issue=6&rft.spage=1317&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268813002082 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-05-01 N1 - Number of references - 30 N1 - Last updated - 2016-03-30 N1 - SubjectsTermNotLitGenreText - Blood culture; medical records; Risk factors; Bacteremia; Pathogens; Infection; Hospitals; Reviews; Rural areas; Acinetobacter; Thailand DO - http://dx.doi.org/10.1017/S0950268813002082 ER - TY - CPAPER T1 - What Does the Evidence Say? T2 - 114th General Meeting of the American Society for Microbiology (ASM 2014) AN - 1518614204; 6284387 JF - 114th General Meeting of the American Society for Microbiology (ASM 2014) AU - Cornish, Nancy Y1 - 2014/05/17/ PY - 2014 DA - 2014 May 17 KW - Microbiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1518614204?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=114th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2014%29&rft.atitle=What+Does+the+Evidence+Say%3F&rft.au=Cornish%2C+Nancy&rft.aulast=Cornish&rft.aufirst=Nancy&rft.date=2014-05-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=114th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2014%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/start.aspx?mkey={673511F0-C86B-432F-A387-058032B8500B} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-04-23 N1 - Last updated - 2014-04-24 ER - TY - CPAPER T1 - Neisseria gonorrhoeae and Antimicrobial Resistance T2 - 114th General Meeting of the American Society for Microbiology (ASM 2014) AN - 1518612956; 6284391 JF - 114th General Meeting of the American Society for Microbiology (ASM 2014) AU - Bolan, Gail Y1 - 2014/05/17/ PY - 2014 DA - 2014 May 17 KW - Antimicrobial resistance KW - Antimicrobial agents KW - Neisseria gonorrhoeae UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1518612956?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=114th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2014%29&rft.atitle=Neisseria+gonorrhoeae+and+Antimicrobial+Resistance&rft.au=Bolan%2C+Gail&rft.aulast=Bolan&rft.aufirst=Gail&rft.date=2014-05-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=114th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2014%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/start.aspx?mkey={673511F0-C86B-432F-A387-058032B8500B} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-04-23 N1 - Last updated - 2014-04-24 ER - TY - CPAPER T1 - Cyclospora cayetanensis Update T2 - 114th General Meeting of the American Society for Microbiology (ASM 2014) AN - 1518612924; 6284224 JF - 114th General Meeting of the American Society for Microbiology (ASM 2014) AU - Herwaldt, Barbara Y1 - 2014/05/17/ PY - 2014 DA - 2014 May 17 KW - Microbiology KW - Cyclospora cayetanensis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1518612924?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=114th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2014%29&rft.atitle=Cyclospora+cayetanensis+Update&rft.au=Herwaldt%2C+Barbara&rft.aulast=Herwaldt&rft.aufirst=Barbara&rft.date=2014-05-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=114th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2014%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/Browse.aspx LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-04-23 N1 - Last updated - 2014-04-24 ER - TY - CPAPER T1 - Meta-analysis and Forest Plots T2 - 114th General Meeting of the American Society for Microbiology (ASM 2014) AN - 1518612919; 6284386 JF - 114th General Meeting of the American Society for Microbiology (ASM 2014) AU - Leibach, Elizabeth Y1 - 2014/05/17/ PY - 2014 DA - 2014 May 17 KW - Reviews KW - Forests UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1518612919?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=114th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2014%29&rft.atitle=Meta-analysis+and+Forest+Plots&rft.au=Leibach%2C+Elizabeth&rft.aulast=Leibach&rft.aufirst=Elizabeth&rft.date=2014-05-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=114th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2014%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/start.aspx?mkey={673511F0-C86B-432F-A387-058032B8500B} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-04-23 N1 - Last updated - 2014-04-24 ER - TY - CPAPER T1 - Perils and Opportunities for Public Health T2 - 114th General Meeting of the American Society for Microbiology (ASM 2014) AN - 1518612350; 6284301 JF - 114th General Meeting of the American Society for Microbiology (ASM 2014) AU - Besser, John Y1 - 2014/05/17/ PY - 2014 DA - 2014 May 17 KW - Public health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1518612350?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=114th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2014%29&rft.atitle=Perils+and+Opportunities+for+Public+Health&rft.au=Besser%2C+John&rft.aulast=Besser&rft.aufirst=John&rft.date=2014-05-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=114th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2014%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/Browse.aspx LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-04-23 N1 - Last updated - 2014-04-24 ER - TY - CPAPER T1 - Quality Improvement at all Phases of the Testing Cycle: Why it is Important and How to Implement an Effective Program T2 - 114th General Meeting of the American Society for Microbiology (ASM 2014) AN - 1518610246; 6284639 JF - 114th General Meeting of the American Society for Microbiology (ASM 2014) AU - Cornish, Nancy Y1 - 2014/05/17/ PY - 2014 DA - 2014 May 17 KW - Quality control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1518610246?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=114th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2014%29&rft.atitle=Quality+Improvement+at+all+Phases+of+the+Testing+Cycle%3A+Why+it+is+Important+and+How+to+Implement+an+Effective+Program&rft.au=Cornish%2C+Nancy&rft.aulast=Cornish&rft.aufirst=Nancy&rft.date=2014-05-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=114th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2014%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/start.aspx?mkey={673511F0-C86B-432F-A387-058032B8500B} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-04-23 N1 - Last updated - 2014-04-24 ER - TY - JOUR T1 - Neglected Parasitic Infections in the United States: Toxocariasis AN - 1647024370; 21184015 AB - Toxocariasis is a preventable parasitic disease that is caused by the dog and cat roundworms Toxocara cani and T. cati, respectively. Humans become infected when they accidently ingest infectious Toxocara eggs commonly found in contaminated soil; children are most often affected. Clinical manifestations of Toxocara infection in humans include ocular toxocariasis and visceral toxocariasis. Although infection with Toxocara can cause devastating disease, the burden of toxocariasis in the United States population remains unknown. In addition, risk factors for acquiring infection need to be better defined, and research needs to be conducted to better understand the pathophysiology and clinical course of toxocariasis. Development of diagnostic tests would enable clinicians to detect active infection, and determination of optimal drug regiments would ensure patients were appropriately treated. Addressing these public health gaps is necessary to understand and address the impact of toxocariasis in the United States. JF - American Journal of Tropical Medicine and Hygiene AU - Woodhall, Dana M AU - Eberhard, Mark L AU - Parise, Monica E AD - Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Mailstop MS A-06, Atlanta, GA 30333, dqw6@cdc.gov Y1 - 2014/05// PY - 2014 DA - May 2014 SP - 810 EP - 813 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 90 IS - 5 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Toxocara KW - Drug development KW - Infection KW - Children KW - Eggs KW - Public health KW - Soil pollution KW - Toxocariasis KW - USA KW - Risk factors KW - Parasitic diseases KW - Hygiene KW - Drugs KW - K 03410:Animal Diseases KW - J 02410:Animal Diseases KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08502:Methods and instruments UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1647024370?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Neglected+Parasitic+Infections+in+the+United+States%3A+Toxocariasis&rft.au=Woodhall%2C+Dana+M%3BEberhard%2C+Mark+L%3BParise%2C+Monica+E&rft.aulast=Woodhall&rft.aufirst=Dana&rft.date=2014-05-01&rft.volume=90&rft.issue=5&rft.spage=810&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.13-0725 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Parasitic diseases; Hygiene; Drugs; Public health; Soil pollution; Toxocariasis; Risk factors; Drug development; Children; Infection; Eggs; Toxocara; USA DO - http://dx.doi.org/10.4269/ajtmh.13-0725 ER - TY - JOUR T1 - Neglected Parasitic Infections in the United States: Toxoplasmosis AN - 1647023832; 21184012 AB - Toxoplasma gondii is a leading cause of severe foodborne illness in the United States. Population-based studies have found T. gondii infection to be more prevalent in racial/ethnic minority and socioeconomically disadvantaged groups. Soil contaminated with cat feces, undercooked meat, and congenital transmission are the principal sources of infection. Toxoplasmosis-associated illnesses include congenital neurologic and ocular disease; acquired illness in immunocompetent persons, most notably ocular disease; and encephalitis or disseminated disease in immunosuppressed persons. The association of T. gondii infection with risk for mental illness is intriguing and requires further research. Reduction of T. gondii in meat, improvements in hygiene and food preparation practices, and reduction of environmental contamination can prevent toxoplasmosis, but more research is needed on how to implement these measures. In addition, screening and treatment may help prevent toxoplasmosis or reduce the severity of disease in some settings. JF - American Journal of Tropical Medicine and Hygiene AU - Jones, Jeffrey L AU - Parise, Monica E AU - Fiore, Anthony E AD - Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Mailstop A-06, Atlanta, GA 30333, jlj1@cdc.gov Y1 - 2014/05// PY - 2014 DA - May 2014 SP - 794 EP - 799 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 90 IS - 5 SN - 0002-9637, 0002-9637 KW - Pollution Abstracts; Microbiology Abstracts B: Bacteriology; Microbiology Abstracts C: Algology, Mycology & Protozoology; Risk Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Food KW - Disease control KW - Socioeconomics KW - Infection KW - Food-borne diseases KW - Disease transmission KW - Mental disorders KW - Neurotransmission KW - Feces KW - Screening KW - Disadvantaged groups KW - Fecal coliforms KW - Population studies KW - Soil contamination KW - Food contamination KW - Toxoplasmosis KW - Encephalitis KW - Meat KW - Soil pollution KW - Health risks KW - USA KW - Toxoplasma gondii KW - Hygiene KW - J 02410:Animal Diseases KW - K 03410:Animal Diseases KW - P 5000:LAND POLLUTION KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08502:Methods and instruments KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1647023832?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Neglected+Parasitic+Infections+in+the+United+States%3A+Toxoplasmosis&rft.au=Jones%2C+Jeffrey+L%3BParise%2C+Monica+E%3BFiore%2C+Anthony+E&rft.aulast=Jones&rft.aufirst=Jeffrey&rft.date=2014-05-01&rft.volume=90&rft.issue=5&rft.spage=794&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.13-0722 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2016-02-04 N1 - SubjectsTermNotLitGenreText - Screening; Disease control; Hygiene; Disease transmission; Soil pollution; Meat; Mental disorders; Neurotransmission; Food; Population studies; Feces; Food contamination; Infection; Encephalitis; Toxoplasmosis; Disadvantaged groups; Health risks; Fecal coliforms; Socioeconomics; Soil contamination; Food-borne diseases; Toxoplasma gondii; USA DO - http://dx.doi.org/10.4269/ajtmh.13-0722 ER - TY - JOUR T1 - Evaluation of adherence to national treatment guidelines among tuberculosis patients in three provinces of South Africa AN - 1560103338; 20636864 AB - Background. Standardised tuberculosis (TB) treatment through directly observed therapy (DOT) is available in South Africa, but the level of adherence to standardised TB treatment and its impact on treatment outcomes is unknown. Objectives. To describe adherence to standardised TB treatment and provision of DOT, and analyse its impact on treatment outcome. Methods. We utilised data collected for an evaluation of the South African national TB surveillance system. A treatment regimen was considered appropriate if based on national treatment guidelines. Multivariate log-binomial regression was used to evaluate the association between treatment regimens, including DOT provision, and treatment outcome. Results. Of 1 339 TB cases in the parent evaluation, 598 (44.7%) were excluded from analysis owing to missing outcome or treatment information. The majority (697, 94.1%) of the remaining 741 patients received an appropriate TB regimen. Almost all patients (717, 96.8%) received DOT, 443 (59.8%) throughout the treatment course and 274 (37.0%) during the intensive (256, 34.6%) or continuation (18, 2.4%) phase. Independent predictors of poor outcome were partial DOT (adjusted risk ratio (aRR) 3.1, 95% confidence interval (CI) 2.2 - 4.3) and previous treatment default (aRR 2.3, 95% CI 1.1 - 4.8). Conclusion. Patients who received incomplete DOT or had a history of defaulting from TB treatment had an increased risk of poor outcomes. JF - South African Medical Journal/Suid-Afrikaanse Mediese Tydskrift AU - Ershova, J V AU - Podewils, L J AU - Bronner, L E AU - Stockwell, H G AU - Dlamini, S AU - Mametja, L D AD - Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, Georgia, USA; College of Public Health, University of South Florida, Tampa, Florida, USA, jhe3@cdc.gov Y1 - 2014/05// PY - 2014 DA - May 2014 SP - 362 EP - 368 PB - Publication Division of the Medical Association of South Africa Private Bag X1 VL - 104 IS - 5 SN - 0256-9574, 0256-9574 KW - Microbiology Abstracts B: Bacteriology KW - Data processing KW - Mycobacterium KW - Tuberculosis KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1560103338?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=South+African+Medical+Journal%2FSuid-Afrikaanse+Mediese+Tydskrift&rft.atitle=Evaluation+of+adherence+to+national+treatment+guidelines+among+tuberculosis+patients+in+three+provinces+of+South+Africa&rft.au=Ershova%2C+J+V%3BPodewils%2C+L+J%3BBronner%2C+L+E%3BStockwell%2C+H+G%3BDlamini%2C+S%3BMametja%2C+L+D&rft.aulast=Ershova&rft.aufirst=J&rft.date=2014-05-01&rft.volume=104&rft.issue=5&rft.spage=362&rft.isbn=&rft.btitle=&rft.title=South+African+Medical+Journal%2FSuid-Afrikaanse+Mediese+Tydskrift&rft.issn=02569574&rft_id=info:doi/10.7196%2FSAMJ.7655 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Last updated - 2015-09-17 N1 - SubjectsTermNotLitGenreText - Data processing; Tuberculosis; Mycobacterium DO - http://dx.doi.org/10.7196/SAMJ.7655 ER - TY - JOUR T1 - Quantification of 21 metabolites of methylnaphthalenes and polycyclic aromatic hydrocarbons in human urine AN - 1554953600; 20285212 AB - Polycyclic aromatic hydrocarbons (PAHs) and their alkylated derivatives, such as methylnaphthalenes (MeNs), are harmful pollutants ubiquitously present in the environment. Exposure to PAHs has been linked to a variety of adverse health effects and outcomes, including cancer. Alkyl PAHs have been proposed as petrogenic source indicators because of their relatively high abundance in unburned petroleum products. We report a method to quantify 11 urinary methylnaphthols (Me-OHNs), metabolites of 1- and 2-methylnaphthalenes, and 10 monohydroxy PAH metabolites (OH-PAHs), using automated liquid-liquid extraction and isotope dilution gas chromatography tandem mass spectrometry (GC-MS/MS). After spiking urine (1 mL) with super(l3)C-labeled internal standards, the conjugated target analytes were hydrolyzed enzymatically in the presence of ascorbic acid. Then, their free species were preconcentrated into 20 % toluene in pentane, derivatized and quantified by GC-MS/MS. The 11 Me-OHNs eluted as 6 distinct chromatographic peaks, each representing 1-3 isomers. Method detection limits were 1.0-41 pg/mL and the coefficients of variation in quality control materials were 4.7-19 %. The method was used to analyze two National Institute of Standards and Technology's Standard Reference Materials and samples from 30 smokers and 30 non-smokers. Geometric mean concentrations were on average 37 (Me-OHNs) and 9.0 (OH-PAHs) fold higher in smokers than in non-smokers. These findings support the usefulness of Me-OHNs as potential biomarkers of non-occupational exposure to MeNs and sources containing MeNs. JF - Analytical and Bioanalytical Chemistry AU - Li, Zheng AU - Romanoff, Lovisa C AU - Trinidad, Debra A AU - Pittman, Erin N AU - Hilton, Donald AU - Hubbard, Kendra AU - Carmichael, Hasan AU - Parker, Jonathan AU - Calafat, Antonia M AU - Sjodin, Andreas AD - Centers for Disease Control and Prevention, National Center for Environmental Health, Division of Laboratory Sciences, 4770 Buford Highway E-53, Atlanta, GA 30341, USA, ZJLi@cdc.gov PY - 2014 SP - 3119 EP - 3129 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 406 IS - 13 SN - 1618-2642, 1618-2642 KW - Pollution Abstracts; Aqualine Abstracts; Water Resources Abstracts; Health & Safety Science Abstracts KW - Polycyclic aromatic hydrocarbon KW - PAH KW - Methylnaphthalene KW - Human exposure KW - Biomonitoring KW - Biomarker KW - Mass Spectrometry KW - Isotopes KW - Toluene KW - Abundance KW - Mass spectrometry KW - Metabolites KW - Pollutants KW - Gas chromatography KW - Exposure KW - Petroleum KW - Bioindicators KW - Polycyclic aromatic hydrocarbons KW - Analytical Methods KW - Urine KW - Quality control KW - Standards KW - Technology KW - AQ 00001:Water Resources and Supplies KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - SW 0810:General KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1554953600?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytical+and+Bioanalytical+Chemistry&rft.atitle=Quantification+of+21+metabolites+of+methylnaphthalenes+and+polycyclic+aromatic+hydrocarbons+in+human+urine&rft.au=Li%2C+Zheng%3BRomanoff%2C+Lovisa+C%3BTrinidad%2C+Debra+A%3BPittman%2C+Erin+N%3BHilton%2C+Donald%3BHubbard%2C+Kendra%3BCarmichael%2C+Hasan%3BParker%2C+Jonathan%3BCalafat%2C+Antonia+M%3BSjodin%2C+Andreas&rft.aulast=Li&rft.aufirst=Zheng&rft.date=2014-05-01&rft.volume=406&rft.issue=13&rft.spage=3119&rft.isbn=&rft.btitle=&rft.title=Analytical+and+Bioanalytical+Chemistry&rft.issn=16182642&rft_id=info:doi/10.1007%2Fs00216-014-7676-0 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-08-01 N1 - Number of references - 60 N1 - Last updated - 2016-01-21 N1 - SubjectsTermNotLitGenreText - Bioindicators; Isotopes; Polycyclic aromatic hydrocarbons; Gas chromatography; Urine; Quality control; Petroleum; Toluene; Abundance; Mass spectrometry; Metabolites; Technology; Mass Spectrometry; Pollutants; Analytical Methods; Exposure; Standards DO - http://dx.doi.org/10.1007/s00216-014-7676-0 ER - TY - JOUR T1 - Prevalence of Obesity by Occupation Among US Workers The National Health Interview Survey 2004-2011 AN - 1547851146; 20285692 AB - Objective: To estimate the prevalence of obesity and the change of prevalence of obesity between 2004-2007 and 2008-20011 by occupation among US workers in the National Health Interview Survey. Methods: Self-reported weight and height were collected and used to assess obesity (body mass index > or = 30 kg/m super(2)). Gender-, race/ethnicity-, and occupation-specific prevalence of obesity were calculated. Results: Prevalence of obesity steadily increased from 2004 through 2008 across gender and race/ethnicity but leveled off from 2008 through 2011. Non-Hispanic black female workers in health care support (49.2%) and transportation/material moving (46.6%) had the highest prevalence of obesity. Prevalence of obesity in relatively low-obesity (white-collar) occupations significantly increased between 2004-2007 and 2008-2011, whereas it did not change significantly in high-obesity (blue-collar) occupations. Conclusions: Workers in all occupational categories are appropriate targets for health promotion and intervention programs to reduce obesity. JF - Journal of Occupational and Environmental Medicine AU - Gu, Ja K AU - Charles, Luenda E AU - Bang, Ki Moon AU - Ma, Claudia C AU - Andrew, Michael E AU - Violanti, John M AU - Burchfiel, Cecil M AD - Biostatistics and Epidemiology Branch, Health Effects Laboratory Division; National Institute for Occupational Safety and Health, HELD/BEB, Mailstop L-4050, 1095 Willowdale Rd, Morgantown, WV 26505, jgu@cdc.gov PY - 2014 SP - 516 EP - 528 PB - Williams & Wilkins, 351 W. Camden St. Baltimore MD 21201 United States VL - 56 IS - 5 SN - 1076-2752, 1076-2752 KW - Health & Safety Science Abstracts KW - Obesity KW - Transportation KW - Health care KW - Body mass KW - Gender KW - Intervention KW - Ethnic groups KW - Health promotion KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1547851146?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Prevalence+of+Obesity+by+Occupation+Among+US+Workers+The+National+Health+Interview+Survey+2004-2011&rft.au=Gu%2C+Ja+K%3BCharles%2C+Luenda+E%3BBang%2C+Ki+Moon%3BMa%2C+Claudia+C%3BAndrew%2C+Michael+E%3BViolanti%2C+John+M%3BBurchfiel%2C+Cecil+M&rft.aulast=Gu&rft.aufirst=Ja&rft.date=2014-05-01&rft.volume=56&rft.issue=5&rft.spage=516&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0000000000000133 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-07-01 N1 - Last updated - 2015-12-23 N1 - SubjectsTermNotLitGenreText - Obesity; Transportation; Health care; Body mass; Gender; Intervention; Ethnic groups; Health promotion DO - http://dx.doi.org/10.1097/JOM.0000000000000133 ER - TY - JOUR T1 - Diabetes and colorectal cancer screening among men and women in the USA: National Health Interview Survey: 2008, 2010 AN - 1524417850; 19633933 AB - Purpose: Adults with diabetes are at increased risk of being diagnosed with and dying from colorectal cancer, but it is unclear whether colorectal cancer screening (CRCS) use is lower in this population. Using the 2008 and 2010 National Health Interview Survey data, we examined whether guideline-concordant CRCS is lower among men and women with self-reported diabetes. Methods: We calculated the weighted percentage of guideline-concordant CRCS and unadjusted and adjusted prevalence ratios (PR) comparing adults aged 51-75 years with diabetes (n = 6,514) to those without (n = 8,371). We also examined effect modification by age (51-64 and 65-75), race/ethnicity, and number of medical office visits (0-3, greater than or equal to 4). Results: The unadjusted prevalence of CRCS among men with diabetes was significantly higher than men without (63.3 vs. 58.0 %; PR = 1.09 95 % CI 1.03-1.16). In adjusted models, this relationship was evident among older [adjusted PR (aPR) = 1.13 95 % CI 1.06-1.21] but not younger men (aPR = 0.99 95 % CI 0.91-1.08; p for interaction term less than or equal to 0.01). There was no significant association between diabetes and CRCS among women overall (56.6 vs. 57.9 %; PR = 0.98 95 % CI 0.92-1.04) or by age group. Race/ethnicity and the number of medical visits did not significantly modify the association between diabetes and CRCS for men or women. Conclusions: Men and women with self-reported diabetes were not less likely to be up to date with CRCS than those without diabetes. Older men with diabetes were more likely to be up to date with CRCS than those without diabetes. JF - Cancer Causes & Control AU - Miller, Eric A AU - Tarasenko, Yelena N AU - Parker, Jennifer D AU - Schoendorf, Kenneth C AD - National Center for Health Statistics, Centers for Disease Control and Prevention, 3311 Toledo Road, Hyattsville, MD, 20782, USA, bwe6@cdc.gov Y1 - 2014/05// PY - 2014 DA - May 2014 SP - 553 EP - 560 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 25 IS - 5 SN - 0957-5243, 0957-5243 KW - Health & Safety Science Abstracts; Risk Abstracts KW - Diabetes mellitus KW - Health risks KW - USA KW - Age KW - Males KW - Colorectal carcinoma KW - Females KW - Ethnic groups KW - Cancer KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1524417850?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cancer+Causes+%26+Control&rft.atitle=Diabetes+and+colorectal+cancer+screening+among+men+and+women+in+the+USA%3A+National+Health+Interview+Survey%3A+2008%2C+2010&rft.au=Miller%2C+Eric+A%3BTarasenko%2C+Yelena+N%3BParker%2C+Jennifer+D%3BSchoendorf%2C+Kenneth+C&rft.aulast=Miller&rft.aufirst=Eric&rft.date=2014-05-01&rft.volume=25&rft.issue=5&rft.spage=553&rft.isbn=&rft.btitle=&rft.title=Cancer+Causes+%26+Control&rft.issn=09575243&rft_id=info:doi/10.1007%2Fs10552-014-0360-z LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-05-01 N1 - Number of references - 32 N1 - Last updated - 2014-06-26 N1 - SubjectsTermNotLitGenreText - Diabetes mellitus; Health risks; Age; Males; Colorectal carcinoma; Females; Cancer; Ethnic groups; USA DO - http://dx.doi.org/10.1007/s10552-014-0360-z ER - TY - JOUR T1 - Exacerbation of symptoms in agricultural pesticide applicators with asthma AN - 1524408233; 19763488 AB - Purpose: Exacerbation is a critical event in asthma management. We investigated whether exacerbation of symptoms is associated with farming exposures among agricultural pesticide applicators with asthma. Methods: Participants were pesticide applicators with active asthma (wheezing and breathing problems in past 12 months) who completed enrollment questionnaires for the Agricultural Health Study (AHS). Exacerbation of asthma was defined as having visited a hospital emergency room or doctor for an episode of wheezing or whistling in the past 12 months. Exposures of interest were using 36 specific pesticides in the past 12 months and conducting various agricultural activities. Adjusted odds ratios (ORs) were estimated by logistic regression while controlling for potential confounders. Results: The 926 AHS adult pesticide applicators with active asthma included 202 (22 %) with exacerbation. Inverse associations with exacerbation were observed for two herbicides [glyphosate, odds ratio (OR) = 0.5, 95 % confidence interval (CI) 0.3, 0.8, and paraquat, OR = 0.3, 95 % CI 0.1, 0.9] and several agricultural activities (repairing engines, grinding metal, driving diesel tractors, and performing veterinary procedures). Only asthma cases with allergies (i.e., doctor-diagnosed hay fever or eczema, 46 %) had positive exacerbation-pesticide associations, with OR = 2.1 (95 % CI 1.1, 4.1) for the herbicide pendimethalin and OR = 10.2 (95 % CI 1.9, 55) for the insecticide aldicarb. Conclusions: The inverse associations with two pesticides and specific farm activities are consistent with the possibility that asthma cases prone to exacerbation may avoid exposures that trigger symptoms. Although limited by small sample size and a cross-sectional design, our study suggests that use of specific pesticides may contribute to exacerbation of asthma among individuals with allergies. JF - International Archives of Occupational and Environmental Health AU - Henneberger, Paul K AU - Liang, Xiaoming AU - London, Stephanie J AU - Umbach, David M AU - Sandler, Dale P AU - Hoppin, Jane A AD - Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, MS 2800, 1095 Willowdale Road, Morgantown, WV, 26505, USA, pkh0@cdc.gov Y1 - 2014/05// PY - 2014 DA - May 2014 SP - 423 EP - 432 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 87 IS - 4 SN - 0340-0131, 0340-0131 KW - Health & Safety Science Abstracts KW - Metals KW - Farms KW - Asthma KW - Herbicides KW - Respiratory diseases KW - Allergies KW - Pendimethalin KW - Insecticides KW - Skin diseases KW - Pesticides KW - Hay fever KW - Agricultural equipment KW - Emergency medical services KW - Hospitals KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1524408233?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Archives+of+Occupational+and+Environmental+Health&rft.atitle=Exacerbation+of+symptoms+in+agricultural+pesticide+applicators+with+asthma&rft.au=Henneberger%2C+Paul+K%3BLiang%2C+Xiaoming%3BLondon%2C+Stephanie+J%3BUmbach%2C+David+M%3BSandler%2C+Dale+P%3BHoppin%2C+Jane+A&rft.aulast=Henneberger&rft.aufirst=Paul&rft.date=2014-05-01&rft.volume=87&rft.issue=4&rft.spage=423&rft.isbn=&rft.btitle=&rft.title=International+Archives+of+Occupational+and+Environmental+Health&rft.issn=03400131&rft_id=info:doi/10.1007%2Fs00420-013-0881-x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-05-01 N1 - Number of references - 30 N1 - Last updated - 2014-05-29 N1 - SubjectsTermNotLitGenreText - Metals; Farms; Asthma; Herbicides; Respiratory diseases; Allergies; Pendimethalin; Insecticides; Skin diseases; Pesticides; Hay fever; Hospitals; Emergency medical services; Agricultural equipment DO - http://dx.doi.org/10.1007/s00420-013-0881-x ER - TY - JOUR T1 - Outbreak of Salmonella enterica serotype I 4,5,12:i:- infections: the challenges of hypothesis generation and microwave cooking AN - 1520371907; 19544272 AB - We investigated an outbreak of 396 Salmonella enterica serotype I 4,5,12:i:- infections to determine the source. After 7 weeks of extensive hypothesis-generation interviews, no refined hypothesis was formed. Nevertheless, a case-control study was initiated. Subsequently, an iterative hypothesis-generation approach used by a single interviewing team identified brand A not-ready-to-eat frozen pot pies as a likely vehicle. The case-control study, modified to assess this new hypothesis, along with product testing indicated that the turkey variety of pot pies was responsible. Review of product labels identified inconsistent language regarding preparation, and the cooking instructions included undefined microwave wattage categories. Surveys found that most patients did not follow the product's cooking instructions and did not know their oven's wattage. The manufacturer voluntarily recalled pot pies and improved the product's cooking instructions. This investigation highlights the value of careful hypothesis-generation and the risks posed by frozen not-ready-to-eat microwavable foods. JF - Epidemiology and Infection AU - Mody, R K AU - Meyer, S AU - Trees, E AU - White, P L AU - Nguyen, T AU - SOWADSKY, R AU - Henao, O L AU - Lafon, P C AU - Austin, J AU - Azzam, I AU - Griffin, P M AU - Tauxe, R V AU - Smith, K AU - Williams, I T AD - Epidemic Intelligence Service, Division of Applied Sciences, Scientific Education and Professional Development Program Office, Centers for Disease Control and Prevention, Atlanta, GA, USA, rmody@cdc.gov Y1 - 2014/05// PY - 2014 DA - May 2014 SP - 1050 EP - 1060 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 142 IS - 5 SN - 0950-2688, 0950-2688 KW - Microbiology Abstracts B: Bacteriology KW - Serotypes KW - Salmonella enterica KW - Cooking KW - Language KW - Infection KW - Frozen food KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1520371907?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Outbreak+of+Salmonella+enterica+serotype+I+4%2C5%2C12%3Ai%3A-+infections%3A+the+challenges+of+hypothesis+generation+and+microwave+cooking&rft.au=Mody%2C+R+K%3BMeyer%2C+S%3BTrees%2C+E%3BWhite%2C+P+L%3BNguyen%2C+T%3BSOWADSKY%2C+R%3BHenao%2C+O+L%3BLafon%2C+P+C%3BAustin%2C+J%3BAzzam%2C+I%3BGriffin%2C+P+M%3BTauxe%2C+R+V%3BSmith%2C+K%3BWilliams%2C+I+T&rft.aulast=Mody&rft.aufirst=R&rft.date=2014-05-01&rft.volume=142&rft.issue=5&rft.spage=1050&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268813001787 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-04-01 N1 - Number of references - 26 N1 - Last updated - 2016-03-30 N1 - SubjectsTermNotLitGenreText - Serotypes; Cooking; Language; Frozen food; Infection; Salmonella enterica DO - http://dx.doi.org/10.1017/S0950268813001787 ER - TY - JOUR T1 - Effect of the 13-Valent Pneumococcal Conjugate Vaccine on Nasopharyngeal Colonization by Streptococcus pneumoniae-Alaska, 2008-2012 AN - 1618151444; 20800381 AB - Background. In 2010, a 13-valent pneumococcal conjugate vaccine (PCV13) replaced a 7-valent vaccine (PCV7) that contained all PCV7 serotypes plus 6 additional serotypes (PCV6+). We conducted annual surveys from 2008 to 2012 to determine the effect of PCV13 on colonization by pneumococcal serotypes. Methods. We obtained nasopharyngeal swabs for pneumococcal identification and serotyping from residents of all ages at 8 rural villages and children age 18 years (14%). Colonization by PCV6+ serotypes declined significantly among rural children age 18 over the course of the (25-5%, 22-9%, 22-6%, 22%-6%, respectively). Conclusions. PCV13 was rapidly introduced into the Alaska childhood immunization schedule and reduced colonization by PCV6+ serotypes among children. Unvaccinated adults also experienced comparable reductions in vaccine serotype colonization indicating substantial indirect protection from PCV13. JF - Journal of Infectious Diseases AU - Gounder, Prabhu P AU - Bruce, Michael G AU - Bruden, Dana J T AU - Singleton, Rosalyn J AU - Rudolph, Karen AU - Hurlburt, Debby A AU - Hennessy, Thomas W AU - Wenger, Jay AD - Arctic Investigations Program, Division of Preparedness and Emerging Infections, National Center for Emerging and Zoonotic Diseases, Centers for Disease Control and Prevention (CDC), 4055 Tudor Centre Dr, Anchorage, Alaska 99508, iym4@cdc.gov Y1 - 2014/04/15/ PY - 2014 DA - 2014 Apr 15 SP - 1251 EP - 1258 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 209 IS - 8 SN - 0022-1899, 0022-1899 KW - Immunology Abstracts; Microbiology Abstracts B: Bacteriology KW - Streptococcus pneumoniae KW - conjugate vaccine KW - nasopharyngeal colonization KW - Alaska Native people KW - Alaska KW - Streptococcus KW - Age KW - Serotypes KW - medical records KW - Serotyping KW - Children KW - Vaccination KW - Immunization KW - Colonization KW - Reviews KW - Vaccines KW - J 02350:Immunology KW - F 06910:Microorganisms & Parasites UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1618151444?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Effect+of+the+13-Valent+Pneumococcal+Conjugate+Vaccine+on+Nasopharyngeal+Colonization+by+Streptococcus+pneumoniae-Alaska%2C+2008-2012&rft.au=Gounder%2C+Prabhu+P%3BBruce%2C+Michael+G%3BBruden%2C+Dana+J+T%3BSingleton%2C+Rosalyn+J%3BRudolph%2C+Karen%3BHurlburt%2C+Debby+A%3BHennessy%2C+Thomas+W%3BWenger%2C+Jay&rft.aulast=Gounder&rft.aufirst=Prabhu&rft.date=2014-04-15&rft.volume=209&rft.issue=8&rft.spage=1251&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjit642 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-10-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Colonization; Age; Serotypes; medical records; Reviews; Serotyping; Vaccines; Children; Vaccination; Immunization; Streptococcus; Streptococcus pneumoniae DO - http://dx.doi.org/10.1093/infdis/jit642 ER - TY - JOUR T1 - Tuberculosis in human immunodeficiency virus-infected children starting antiretroviral therapy in Cote d'Ivoire AN - 1551623043; 20180427 AB - SETTING: In Cote d'Ivoire, more than 2000 human immunodeficiency virus (HFV) infected children aged <15 years were started on antiretroviral therapy (ART) during 2004-2008. OBJECTIVES: To estimate tuberculosis (TB) incidence and determinants among ART enrollees. DESIGN: A nationally representative retrospective cohort study among 2110 children starting ART during 2004-2008 at 29 facilities. RESULTS: At ART initiation, the median age was 5.1 years; 82% had World Health Organization Stage III/TV, median CD4% was 11%, 42% were severely undernourished (weight-for-age Z-score [WAZ] <-3), and 150 (7%) were taking anti-tuberculosis treatment. Documentation of TB screening before ART declined from 63% to 46% during 2004-2008. Children taking antituberculosis treatment at ART enrollment had a lower median CD4% (9.0% vs. 11.0%, P = 0.037) and a higher prevalence of WAZ <-3 (59% vs. 40%, P < 0.001). Among children considered TB-free at ART enrollment, TB incidence was 6.28/100 child-years during days 0-90 of ART, declining to 0.56/100 childyears after 180 days. Children with one unit higher WAZ at ART enrollment had 13% lower TB incidence (adjusted HR 0.87, 95%CI 0.77-1.00, P = 0.047). CONCLUSIONS: Ensuring clinician compliance with TB screening before ART and ensuring earlier ART initiation before children suffer from advanced HIV disease and nutritional compromise might reduce TB morbidity during ART. JF - International Journal of Tuberculosis and Lung Disease AU - Auld, A F AU - Tuho, M Z AU - Ekra, K A AU - Kouakou, J AU - Shiraishi, R W AU - Adjorlolo-Johnson, G AU - Marlink, R AU - Ellerbrock, T V AD - Division of Global HIV/AIDS, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, USA; HIV Care and Treatment Team, Division of Global HIV/AIDS (DGHA), Center for Global Health (CGH), US Centers for Disease Control and Prevention (CDC), 1600 Clifton Road, Mailstop-E04, Atlanta, GA 30333, USA, aauld@cdc.gov Y1 - 2014/04// PY - 2014 DA - Apr 2014 SP - 381 EP - 387 PB - International Union Against Tuberculosis and Lung Disease, 68 bvd Saint-Michel Paris 75006 France VL - 18 IS - 4 SN - 1027-3719, 1027-3719 KW - Virology & AIDS Abstracts; Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - pediatric KW - incident tuberculosis KW - tuberculosis screening KW - Ivory Coast KW - CD4 antigen KW - Age KW - Human immunodeficiency virus KW - Mycobacterium KW - antiretroviral therapy KW - Lung diseases KW - Immunodeficiency KW - Tuberculosis KW - Children KW - Morbidity KW - V 22360:AIDS and HIV KW - J 02400:Human Diseases KW - F 06910:Microorganisms & Parasites UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1551623043?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Tuberculosis+in+human+immunodeficiency+virus-infected+children+starting+antiretroviral+therapy+in+Cote+d%27Ivoire&rft.au=Auld%2C+A+F%3BTuho%2C+M+Z%3BEkra%2C+K+A%3BKouakou%2C+J%3BShiraishi%2C+R+W%3BAdjorlolo-Johnson%2C+G%3BMarlink%2C+R%3BEllerbrock%2C+T+V&rft.aulast=Auld&rft.aufirst=A&rft.date=2014-04-01&rft.volume=18&rft.issue=4&rft.spage=381&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/10.5588%2Fijtld.13.0395 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-08-01 N1 - Last updated - 2015-04-16 N1 - SubjectsTermNotLitGenreText - Age; CD4 antigen; antiretroviral therapy; Immunodeficiency; Lung diseases; Tuberculosis; Children; Morbidity; Mycobacterium; Human immunodeficiency virus DO - http://dx.doi.org/10.5588/ijtld.13.0395 ER - TY - JOUR T1 - Risk factors for sporadic infection with Salmonella Infantis: a matched case-control study AN - 1540223882; 19371745 AB - This matched case-control study investigated the risk factors for sporadic Salmonella Infantis infection in 263 affected children and 263 age-, gender- and neighbourhood-matched controls. Information about exposure to potential risk factors was obtained via telephone interview and evaluated by conditional logistic regression analysis. Age groups 1 year (n = 77) and >1 year (n = 186) were analysed separately. Of those aged 1 year, breastfeeding was a significant protective factor against infection [matched odds ratio (mOR) 0.24, 95% confidence interval (CI) 0.10-0.59, P < 0.01]. In the older group, consumption of eggs (mOR 1.87, 95% CI 1.00-3.49, P = 0.05) was a significant risk factor and thawing chicken in water (mOR 2.55, 95% CI 0.94-6.91, P = 0.07) was borderline risk factor, while consumption of carrots (mOR 0.46, 95% CI 0.26-0.83, P < 0.01), drinking tap water (mOR 0.44, 95% CI 0.22-0.85, P = 0.02), religious lifestyle (mOR 0.40, 95% CI 0.21-0.74, P < 0.01) and having a high number of children in the household (mOR 0.72, 95% CI 0.58-0.88, P < 0.01) were significant protective factors. Consumers should avoid eating undercooked eggs and food handlers should be educated regarding proper handling and cooking of eggs. Breastfeeding should be strongly encouraged by public health authorities. The public must be educated on stringent hygiene practices, especially proper cooking of eggs to reduce infection rates. JF - Epidemiology and Infection AU - Bassal, R AU - Reisfeld, A AU - Nissan, I AU - Agmon, V AU - Taran, D AU - SCHEMBERG, B AU - Cohen, D AU - Shohat, T AD - Israel Center for Disease Control, Ministry of Health, Tel Hashomer, Israel, ravit.bassal@moh.health.gov.il PY - 2014 SP - 820 EP - 825 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 142 IS - 4 SN - 0950-2688, 0950-2688 KW - Health & Safety Science Abstracts; Microbiology Abstracts B: Bacteriology; Risk Abstracts KW - Age KW - Food KW - Daucus KW - Infection KW - Eggs KW - Thawing KW - Public health KW - Risk factors KW - Cooking KW - Regression analysis KW - Consumers KW - Breast feeding KW - Handlers KW - Children KW - Chickens KW - Households KW - Age groups KW - Drinking water KW - Hygiene KW - Salmonella infantis KW - H 12000:Epidemiology and Public Health KW - J 02400:Human Diseases KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1540223882?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Risk+factors+for+sporadic+infection+with+Salmonella+Infantis%3A+a+matched+case-control+study&rft.au=Bassal%2C+R%3BReisfeld%2C+A%3BNissan%2C+I%3BAgmon%2C+V%3BTaran%2C+D%3BSCHEMBERG%2C+B%3BCohen%2C+D%3BShohat%2C+T&rft.aulast=Bassal&rft.aufirst=R&rft.date=2014-04-01&rft.volume=142&rft.issue=4&rft.spage=820&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268813001799 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-06-01 N1 - Number of references - 21 N1 - Last updated - 2016-01-21 N1 - SubjectsTermNotLitGenreText - Age; Food; Handlers; Infection; Children; Eggs; Public health; Thawing; Risk factors; Cooking; Regression analysis; Breast feeding; Consumers; Hygiene; Drinking water; Chickens; Households; Age groups; Daucus; Salmonella infantis DO - http://dx.doi.org/10.1017/S0950268813001799 ER - TY - JOUR T1 - Predictors of Never Being Screened for Cervical Cancer by Metropolitan Area AN - 1540223583; 19363299 AB - Previous studies have shown an association between cervical cancer screening and racial/ethnic minority status, no usual source of care, and lower socioeconomic status. This study describes the demographics and health beliefs of women who report never being screened for cervical cancer by area of residence. Data from the 2010 Behavioral Risk Factor Surveillance System were used to study women aged 21-65 years who reported never being screened for cervical cancer. Multivariate logistic regression modeling was used to calculate predicted marginals to examine associations between never being screened and demographic characteristics and health belief model (HBM) constructs by metropolitan statistical area (MSA). After adjusting for all demographics and HBM constructs, prevalence of never being screened was higher for the following women: non-Hispanic Asians/Native Hawaiians/Pacific Islanders (16.5 %, 95 % CI = 13.7 %, 19.8 %) who live in MSAs; those with only a high school diploma who live in MSAs (5.5 %, 95 % CI = 4.7 %, 6.5 %); those living in non-MSAs who reported "fair or poor" general health (4.1 %, 95 % CI = 3.1 %, 5.4 %); and those living in either MSAs and non-MSAs unable to see a doctor within the past 12 months because of cost (MSA: 4.4 %, 95 % CI = 4.0 %, 4.8 %; non-MSA: 3.4 %, 95 % CI = 2.9 %, 3.9 %). The Affordable Care Act will expand access to insurance coverage for cervical cancer screening, without cost sharing for millions of women, essentially eliminating insurance costs as a barrier. Future interventions for women who have never been screened should focus on promoting the importance of screening and reaching non-Hispanic Asians/Native Hawaiians/Pacific Islanders who live in MSAs. JF - Journal of Community Health AU - Stanley, Sandte L AU - Thomas, Cheryll C AU - King, Jessica B AU - Richardson, Lisa C AD - Centers for Disease Control and Prevention, 1600 Clifton Road NE, E-64, 30333, Atlanta, GA, USA, lrichardson@cdc.gov Y1 - 2014/04// PY - 2014 DA - Apr 2014 SP - 400 EP - 408 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 39 IS - 2 SN - 0094-5145, 0094-5145 KW - Risk Abstracts KW - Demography KW - Health risks KW - Risk factors KW - I, Pacific KW - Socioeconomics KW - Intervention KW - Insurance KW - Cancer KW - Metropolitan areas KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1540223583?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Community+Health&rft.atitle=Predictors+of+Never+Being+Screened+for+Cervical+Cancer+by+Metropolitan+Area&rft.au=Stanley%2C+Sandte+L%3BThomas%2C+Cheryll+C%3BKing%2C+Jessica+B%3BRichardson%2C+Lisa+C&rft.aulast=Stanley&rft.aufirst=Sandte&rft.date=2014-04-01&rft.volume=39&rft.issue=2&rft.spage=400&rft.isbn=&rft.btitle=&rft.title=Journal+of+Community+Health&rft.issn=00945145&rft_id=info:doi/10.1007%2Fs10900-013-9778-6 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-06-01 N1 - Number of references - 44 N1 - Last updated - 2014-06-26 N1 - SubjectsTermNotLitGenreText - Demography; Health risks; Risk factors; Intervention; Socioeconomics; Insurance; Metropolitan areas; Cancer; I, Pacific DO - http://dx.doi.org/10.1007/s10900-013-9778-6 ER - TY - JOUR T1 - The Impact of Alcohol Use on HIV/STI Intervention Efficacy in Predicting Sexually Transmitted Infections Among Young African-American Women AN - 1516738569; 19505447 AB - The impact of alcohol use on the efficacy of an HIV/STI intervention designed for young African-American women in predicting STIs was examined. Eight hundred forty-eight African-American women, 18-29 years, were randomly assigned to either the HIV/STI intervention or a control condition. Participants were assessed on alcohol use and provided two vaginal swab specimens for STI testing. Women in the intervention who consumed alcohol were less likely to test STI-positive than women in the control and abstainers (AOR = 2.47, 95 % CI = 1.01-6.22). STI risk factors may vary across different populations. Further research on heavy drinking and HIV intervention efficacy is needed. JF - AIDS and Behavior AU - Seth, Puja AU - Wingood, Gina M AU - Robinson, LaShun S AU - DiClemente, Ralph J AD - Department of Behavioral Sciences and Health Education, Rollins School of Public Health, Emory University, 1600 Clifton Road NE, MS E-59, Atlanta, GA, 30333, USA, pseth@cdc.gov Y1 - 2014/04// PY - 2014 DA - Apr 2014 SP - 747 EP - 751 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 18 IS - 4 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Risk Abstracts KW - Alcohol KW - Acquired immune deficiency syndrome KW - Intervention KW - Infection KW - Infectious diseases KW - Human immunodeficiency virus KW - Risk factors KW - Vagina KW - alcohols KW - Drinking behavior KW - Females KW - Ethnic groups KW - Sexually transmitted diseases KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1516738569?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=The+Impact+of+Alcohol+Use+on+HIV%2FSTI+Intervention+Efficacy+in+Predicting+Sexually+Transmitted+Infections+Among+Young+African-American+Women&rft.au=Seth%2C+Puja%3BWingood%2C+Gina+M%3BRobinson%2C+LaShun+S%3BDiClemente%2C+Ralph+J&rft.aulast=Seth&rft.aufirst=Puja&rft.date=2014-04-01&rft.volume=18&rft.issue=4&rft.spage=747&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-013-0555-4 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-04-01 N1 - Number of references - 12 N1 - Last updated - 2014-06-26 N1 - SubjectsTermNotLitGenreText - Risk factors; Vagina; alcohols; Drinking behavior; Infection; Alcohol; Acquired immune deficiency syndrome; Infectious diseases; Human immunodeficiency virus; Intervention; Females; Sexually transmitted diseases; Ethnic groups DO - http://dx.doi.org/10.1007/s10461-013-0555-4 ER - TY - JOUR T1 - Can an evidence-based fall prevention program be translated for use in culturally diverse communities? AN - 1790939966; PQ0003073053 AB - Older adult falls are a significant public health problem, but one that is amenable to preventive interventions.1,2 Despite the progress made in identifying risk factors,developing efficacious health-related interventions,and promoting evidencebased programs in the community, much work remains before these strategies are broadly available and effectively used to reduce fall-related injuries. JF - Journal of Sport and Health Science AU - Sleet, David A AU - Baldwin, Grant T AD - Centers for Disease Control and Prevention, Atlanta, GA 30341, USA, dds6@cdc.gov Y1 - 2014/03// PY - 2014 DA - March 2014 SP - 32 EP - 33 PB - Journal of Sport and Health Science, 650 Qingyuanhuan Road Shanghai 200438 China VL - 3 IS - 1 SN - 2095-2546, 2095-2546 KW - Physical Education Index KW - Preventive health KW - Strategy KW - Gerontology KW - Work KW - Sport science KW - Health (programs) KW - Health KW - Adults KW - Public health KW - PE 090:Sports Medicine & Exercise Sport Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1790939966?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Sport+and+Health+Science&rft.atitle=Can+an+evidence-based+fall+prevention+program+be+translated+for+use+in+culturally+diverse+communities%3F&rft.au=Sleet%2C+David+A%3BBaldwin%2C+Grant+T&rft.aulast=Sleet&rft.aufirst=David&rft.date=2014-03-01&rft.volume=3&rft.issue=1&rft.spage=32&rft.isbn=&rft.btitle=&rft.title=Journal+of+Sport+and+Health+Science&rft.issn=20952546&rft_id=info:doi/10.1016%2Fj.jshs.2013.11.001 LA - English DB - Physical Education Index N1 - Date revised - 2016-05-01 N1 - Last updated - 2016-06-22 N1 - SubjectsTermNotLitGenreText - Preventive health; Strategy; Gerontology; Sport science; Work; Health; Health (programs); Adults; Public health DO - http://dx.doi.org/10.1016/j.jshs.2013.11.001 ER - TY - JOUR T1 - Microbial Biofilms on Needleless Connectors for Central Venous Catheters: Comparison of Standard and Silver-Coated Devices Collected from Patients in an Acute Care Hospital AN - 1694967669; 19446571 AB - Microorganisms may colonize needleless connectors (NCs) on intravascular catheters, forming biofilms and predisposing patients to catheter-associated infection (CAI). Standard and silver-coated NCs were collected from catheterized intensive care unit patients to characterize biofilm formation using culture-dependent and culture-independent methods and to investigate the associations between NC usage and biofilm characteristics. Viable microorganisms were detected by plate counts from 46% of standard NCs and 59% of silver-coated NCs (P = 0.11). There were no significant associations (P > 0.05, chi-square test) between catheter type, side of catheter placement, number of catheter lumens, site of catheter placement, or NC placement duration and positive NC findings. There was an association (P = 0.04, chi-square test) between infusion type and positive findings for standard NCs. Viable microorganisms exhibiting intracellular esterase activity were detected on >90% of both NC types (P = 0.751), suggesting that a large percentage of organisms were not culturable using the conditions provided in this study. Amplification of the 16S rRNA gene from selected NCs provided a substantially larger number of operational taxonomic units per NC than did plate counts (26 to 43 versus 1 to 4 operational taxonomic units/NC, respectively), suggesting that culture-dependent methods may substantially underestimate microbial diversity on NCs. NC bacterial communities were clustered by patient and venous access type and may reflect the composition of the patient's local microbiome but also may contain organisms from the health care environment. NCs provide a portal of entry for a wide diversity of opportunistic pathogens to colonize the catheter lumen, forming a biofilm and increasing the potential for CAI, highlighting the importance of catheter maintenance practices to reduce microbial contamination. JF - Journal of Clinical Microbiology AU - Perez, Elizabeth AU - Williams, Margaret AU - Jacob, Jesse T AU - Reyes, Mary Dent AU - Tejedor, Sheri Chernetsky AU - Steinberg, James P AU - Rowe, Lori AU - Ganakammal, Satishkumar Ranganathan AU - Changayil, Shankar AU - Weil, M Ryan AD - Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, rld8@cdc.gov. Y1 - 2014/03// PY - 2014 DA - March 2014 SP - 823 EP - 831 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 52 IS - 3 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts A: Industrial & Applied Microbiology KW - Contamination KW - Intensive care units KW - esterase KW - Catheters KW - Microorganisms KW - Biofilms KW - Pathogens KW - Infection KW - rRNA 16S KW - Hospitals KW - A 01450:Environmental Pollution & Waste Treatment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1694967669?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Microbial+Biofilms+on+Needleless+Connectors+for+Central+Venous+Catheters%3A+Comparison+of+Standard+and+Silver-Coated+Devices+Collected+from+Patients+in+an+Acute+Care+Hospital&rft.au=Perez%2C+Elizabeth%3BWilliams%2C+Margaret%3BJacob%2C+Jesse+T%3BReyes%2C+Mary+Dent%3BTejedor%2C+Sheri+Chernetsky%3BSteinberg%2C+James+P%3BRowe%2C+Lori%3BGanakammal%2C+Satishkumar+Ranganathan%3BChangayil%2C+Shankar%3BWeil%2C+M+Ryan&rft.aulast=Perez&rft.aufirst=Elizabeth&rft.date=2014-03-01&rft.volume=52&rft.issue=3&rft.spage=823&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.02220-13 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-07-01 N1 - Number of references - 32 N1 - Last updated - 2016-07-20 N1 - SubjectsTermNotLitGenreText - Intensive care units; Contamination; esterase; Microorganisms; Catheters; Pathogens; Biofilms; Infection; rRNA 16S; Hospitals DO - http://dx.doi.org/10.1128/JCM.02220-13 ER - TY - JOUR T1 - Complications and Associated Bacterial Coinfections Among Children Hospitalized With Seasonal or Pandemic Influenza, United States, 2003-2010 AN - 1618159811; 20843312 AB - Background. Data Data on the range and severity of influenza-associated complications among children are limited. We describe frequency frequency and severity of complications in hospitalized children aged or =2 years), and dehydration (in 21%). Lung abscess/empyema, tracheitis, encephalopathy, bacteremia/sepsis, acute renal failure, and myocarditis were rare (each [ or =6 days, and 48%-70% of children required intensive care. Bacterial cultures with positive results were identified in 2% of children (107/6769); Staphylococcus aureus and Streptococcus pneumoniae were most commonly identified. Conclusions. Complications contribute substantially to the disease burden among children hospitalized with influenza, through intensive care requirements and prolonged hospitalization, highlighting the importance of primary prevention with influenza vaccination. JF - Journal of Infectious Diseases AU - Dawood, Fatimah S AU - Chaves, Sandra S AU - Perez, Alejandro AU - Reingold, Arthur AU - Meek, James AU - Farley, Monica M AU - Ryan, Patricia AU - Lynfield, Ruth AU - Morin, Craig AU - Baumbach, Joan AD - Influenza Division, Centers for Disease Control and Prevention, 1600 Clifton Rd, MS A-32, Atlanta, GA 30333, fdawood@cdc.gov Y1 - 2014/03/01/ PY - 2014 DA - 2014 Mar 01 SP - 686 EP - 694 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 209 IS - 5 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts; Microbiology Abstracts B: Bacteriology KW - influenza KW - complications KW - bacterial infection KW - children KW - children, hospitalized KW - Tracheitis KW - Respiratory diseases KW - Renal KW - Influenza KW - pandemics KW - Sulfur dioxide KW - Infectious diseases KW - Classification KW - Myocarditis KW - Staphylococcus aureus KW - Encephalopathy KW - Seasonal variations KW - Heart diseases KW - Data processing KW - Complications KW - medical records KW - Renal failure KW - Asthma KW - Bacteremia KW - Empyema KW - Abscesses KW - Children KW - Vaccination KW - USA KW - Streptococcus pneumoniae KW - Prevention KW - Sepsis KW - Lung KW - Vaccines KW - Pneumonia KW - Hospitals KW - Dehydration KW - H 1000:Occupational Safety and Health KW - J 02350:Immunology KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1618159811?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Complications+and+Associated+Bacterial+Coinfections+Among+Children+Hospitalized+With+Seasonal+or+Pandemic+Influenza%2C+United+States%2C+2003-2010&rft.au=Dawood%2C+Fatimah+S%3BChaves%2C+Sandra+S%3BPerez%2C+Alejandro%3BReingold%2C+Arthur%3BMeek%2C+James%3BFarley%2C+Monica+M%3BRyan%2C+Patricia%3BLynfield%2C+Ruth%3BMorin%2C+Craig%3BBaumbach%2C+Joan&rft.aulast=Dawood&rft.aufirst=Fatimah&rft.date=2014-03-01&rft.volume=209&rft.issue=5&rft.spage=686&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjit473 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-10-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Data processing; medical records; Tracheitis; Bacteremia; Asthma; Renal failure; Empyema; Children; Abscesses; Vaccination; Influenza; Sepsis; pandemics; Classification; Lung; Myocarditis; Encephalopathy; Pneumonia; Dehydration; Heart diseases; Complications; Respiratory diseases; Renal; Prevention; Sulfur dioxide; Infectious diseases; Vaccines; Seasonal variations; Hospitals; Streptococcus pneumoniae; Staphylococcus aureus; USA DO - http://dx.doi.org/10.1093/infdis/jit473 ER - TY - JOUR T1 - Detection and Characterization of Mycoplasma pneumoniae during an Outbreak of Respiratory Illness at a University AN - 1516760451; 19446591 AB - An outbreak at a university in Georgia was identified after 83 cases of probable pneumonia were reported among students. Respiratory specimens were obtained from 21 students for the outbreak investigation. The TaqMan array card (TAC), a quantitative PCR (qPCR)-based multipathogen detection technology, was used to initially identify Mycoplasma pneumoniae as the causative agent in this outbreak. TAC demonstrated 100% diagnostic specificity and sensitivity compared to those of the multiplex qPCR assay for this agent. All M. pneumoniae specimens (n = 12) and isolates (n = 10) were found through genetic analysis to be susceptible to macrolide antibiotics. The strain diversity of M. pneumoniae associated with this outbreak setting was identified using a variety of molecular typing procedures, resulting in two P1 genotypes (types 1 [60%] and 2 [40%]) and seven different multilocus variable-number tandem-repeat analysis (MLVA) profiles. Continued molecular typing of this organism, particularly during outbreaks, may enhance the current understanding of the epidemiology of M. pneumoniae and may ultimately lead to a more effective public health response. JF - Journal of Clinical Microbiology AU - Waller, Jessica L AU - Diaz, Maureen H AU - Petrone, Brianna L AU - Benitez, Alvaro J AU - Wolff, Bernard J AU - Edison, Laura AU - Tobin-D'Angelo, Melissa AU - Moore, Ashley AU - Martyn, Audrey AU - Dishman, Hope AD - Respiratory Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, jwinchell@cdc.gov. Y1 - 2014/03// PY - 2014 DA - March 2014 SP - 849 EP - 853 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 52 IS - 3 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts KW - Sensitivity KW - Genetic analysis KW - USA, Georgia KW - Antibiotics KW - Genotypes KW - Mycoplasma pneumoniae KW - Macrolide antibiotics KW - Public health KW - Epidemiology KW - Polymerase chain reaction KW - Outbreaks KW - Pneumonia KW - Technology KW - J 02400:Human Diseases KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1516760451?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Detection+and+Characterization+of+Mycoplasma+pneumoniae+during+an+Outbreak+of+Respiratory+Illness+at+a+University&rft.au=Waller%2C+Jessica+L%3BDiaz%2C+Maureen+H%3BPetrone%2C+Brianna+L%3BBenitez%2C+Alvaro+J%3BWolff%2C+Bernard+J%3BEdison%2C+Laura%3BTobin-D%27Angelo%2C+Melissa%3BMoore%2C+Ashley%3BMartyn%2C+Audrey%3BDishman%2C+Hope&rft.aulast=Waller&rft.aufirst=Jessica&rft.date=2014-03-01&rft.volume=52&rft.issue=3&rft.spage=849&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.02810-13 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-04-01 N1 - Number of references - 27 N1 - Last updated - 2016-07-20 N1 - SubjectsTermNotLitGenreText - Epidemiology; Genetic analysis; Polymerase chain reaction; Genotypes; Macrolide antibiotics; Pneumonia; Public health; Sensitivity; Antibiotics; Outbreaks; Technology; Mycoplasma pneumoniae; USA, Georgia DO - http://dx.doi.org/10.1128/JCM.02810-13 ER - TY - JOUR T1 - Development and use of the generic WHO/CDC logic model for vitamin and mineral interventions in public health programmes AN - 1516748827; 19560248 AB - Nutrition interventions are critical to achieve the Millennium Development Goals; among them, micronutrient interventions are considered cost-effective and programmatically feasible to scale up, but there are limited tools to communicate the programme components and their relationships. The WHO/CDC (Centers for Disease Control and Prevention) logic model for micronutrient interventions in public health programmes is a useful resource for planning, implementation, monitoring and evaluation of these interventions, which depicts the programme theory and expected relationships between inputs and expected Millennium Development Goals. The model was developed by applying principles of programme evaluation, public health nutrition theory and programmatic expertise. The multifaceted and iterative structure validation included feedback from potential users and adaptation by national stakeholders involved in public health programmes' design and implementation. In addition to the inputs, main activity domains identified as essential for programme development, implementation and performance include: (i) policy; (ii) products and supply; (iii) delivery systems; (iv) quality control; and (v) behaviour change communication. Outputs encompass the access to and coverage of interventions. Outcomes include knowledge and appropriate use of the intervention, as well as effects on micronutrient intake, nutritional status and health of target populations, for ultimate achievement of the Millennium Development Goals. The WHO/CDC logic model simplifies the process of developing a logic model by providing a tool that has identified high-priority areas and concepts that apply to virtually all public health micronutrient interventions. Countries can adapt it to their context in order to support programme design, implementation, monitoring and evaluation for the successful scale-up of nutrition interventions in public health. JF - Public Health Nutrition AU - De-Regil, Luz Maria AU - Pena-Rosas, Juan Pablo AU - Flores-Ayala, Rafael AU - del Socorro Jefferds, Maria Elena AD - Evidence and Programme Guidance, Department of Nutrition for Health and Development, World Health Organization, Geneva, Switzerland, mnj5@cdc.gov Y1 - 2014/03// PY - 2014 DA - Mar 2014 SP - 634 EP - 639 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 17 IS - 3 SN - 1368-9800, 1368-9800 KW - Health & Safety Science Abstracts KW - Stakeholders KW - Disease control KW - Intervention KW - Nutrition KW - Public health KW - Prevention KW - Adaptability KW - Communications KW - Quality control KW - Vitamins KW - Economics KW - Micronutrients KW - Minerals KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1516748827?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Public+Health+Nutrition&rft.atitle=Development+and+use+of+the+generic+WHO%2FCDC+logic+model+for+vitamin+and+mineral+interventions+in+public+health+programmes&rft.au=De-Regil%2C+Luz+Maria%3BPena-Rosas%2C+Juan+Pablo%3BFlores-Ayala%2C+Rafael%3Bdel+Socorro+Jefferds%2C+Maria+Elena&rft.aulast=De-Regil&rft.aufirst=Luz&rft.date=2014-03-01&rft.volume=17&rft.issue=3&rft.spage=634&rft.isbn=&rft.btitle=&rft.title=Public+Health+Nutrition&rft.issn=13689800&rft_id=info:doi/10.1017%2FS1368980013000554 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-04-01 N1 - Number of references - 10 N1 - Last updated - 2014-05-02 N1 - SubjectsTermNotLitGenreText - Stakeholders; Disease control; Intervention; Nutrition; Public health; Adaptability; Prevention; Communications; Vitamins; Quality control; Economics; Micronutrients; Minerals DO - http://dx.doi.org/10.1017/S1368980013000554 ER - TY - JOUR T1 - On the role of poison centers in radiation emergency preparedness and response activities: findings of the "Radiation Emergencies Public Health Roundtable" (Atlanta, GA-August 2012). AN - 1507799286; 24366541 JF - Journal of medical toxicology : official journal of the American College of Medical Toxicology AU - Pomerleau, A C AU - Schauben, J L AU - Bronstein, A C AU - Chang, A S AD - Radiation Studies Branch, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA, von9@cdc.gov. Y1 - 2014/03// PY - 2014 DA - March 2014 SP - 107 EP - 111 VL - 10 IS - 1 KW - Index Medicus KW - United States KW - Information Systems -- manpower KW - Professional Role KW - Centers for Disease Control and Prevention (U.S.) KW - Humans KW - Societies, Scientific KW - Radiologic Health -- standards KW - Radiologic Health -- manpower KW - Radiologic Health -- education KW - Poison Control Centers -- manpower KW - Radioactive Hazard Release KW - Disaster Planning UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1507799286?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+medical+toxicology+%3A+official+journal+of+the+American+College+of+Medical+Toxicology&rft.atitle=On+the+role+of+poison+centers+in+radiation+emergency+preparedness+and+response+activities%3A+findings+of+the+%22Radiation+Emergencies+Public+Health+Roundtable%22+%28Atlanta%2C+GA-August+2012%29.&rft.au=Pomerleau%2C+A+C%3BSchauben%2C+J+L%3BBronstein%2C+A+C%3BChang%2C+A+S&rft.aulast=Pomerleau&rft.aufirst=A&rft.date=2014-03-01&rft.volume=10&rft.issue=1&rft.spage=107&rft.isbn=&rft.btitle=&rft.title=Journal+of+medical+toxicology+%3A+official+journal+of+the+American+College+of+Medical+Toxicology&rft.issn=1937-6995&rft_id=info:doi/10.1007%2Fs13181-013-0363-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2014-12-09 N1 - Date created - 2014-03-13 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Cited By: Ann Emerg Med. 2012 Jan;59(1):56-61 [21937144] Clin Toxicol (Phila). 2012 Dec;50(10):911-1164 [23272763] Clin Toxicol (Phila). 2013 Jan;51(1):41-6 [23043524] Health Phys. 2011 Nov;101(5):551-8 [21979539] Am J Prev Med. 2010 Jun;38(6):658-62 [20494243] MMWR Morb Mortal Wkly Rep. 2010 Sep 17;59(36):1178-81 [20847721] Am J Disaster Med. 2010 Jul-Aug;5(4):229-36 [20879505] Environ Health Perspect. 2006 Dec;114(12):1853-8 [17185275] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1007/s13181-013-0363-2 ER - TY - JOUR T1 - Accessing HIV testing and treatment among men who have sex with men in China: a qualitative study AN - 1499081796; 4528520 AB - Barriers to HIV testing and HIV care and treatment pose significant challenges to HIV prevention among men who have sex with men (MSM) in China. We carried out a qualitative study to identify barriers and facilitators to HIV testing and treatment among Chinese MSM. In 2012, seven focus group (FG) discussions were conducted with 49 MSM participants in Nanjing, China. Purposive sampling was used to recruit a diverse group of MSM participants. Semi-structured interviews were conducted to collect FG data. Major barriers to testing included gay- and HIV-related stigma and discrimination, relationship type and partner characteristics, low perception of risk or threat, HIV is incurable or equals death, concerns of confidentiality, unaware that testing is offered for free, and name-based testing. Key facilitators of testing included engaging in high-risk sex, sense of responsibility for partner, collectivism, testing as a part of standard/routine medical care, MSM-friendly medical personnel, increased acceptance of gay/bisexual men by the general public, legal recognition and protection of homosexuals, and home self-testing. Barriers to treatment included negative coping, nondisclosure to families, misconceptions of domestically produced antiretroviral drugs (ARVs) and the benefits of treatment, and costs associated with long-term treatment. Facilitators of treatment included sense of hopefulness that a cure would be found, the cultural value of longevity, peer social support and professional psychological counseling, affordable and specialized treatment and care, and reduced HIV-related stigma and discrimination. Finally, for both testing and treatment, more educational and promotional activities within MSM communities and among the general public are needed. Reprinted by permission of Routledge, Taylor & Francis Ltd. JF - AIDS care AU - Wei, Chongyi AU - Yan, Hongjing AU - Yang, Chuankun AU - Raymond, H Fisher AU - Li, Jianjun AU - Yang, Haitao AU - Zhao, Jinkou AU - Huan, Xiping AU - Stall, Ron AD - University of Pittsburgh ; Jiangsu Provincial Center for Disease Control and Prevention ; University of California, San Francisco ; Jiangsu Provincial Center for Disease Controland Prevention ; Global Fund to Fight AIDS Y1 - 2014/03// PY - 2014 DA - Mar 2014 SP - 372 EP - 378 VL - 26 IS - 3 SN - 0954-0121, 0954-0121 KW - Sociology KW - Qualitative analysis KW - Gender KW - Sexual health KW - HIV KW - Stigma KW - China UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1499081796?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+care&rft.atitle=Accessing+HIV+testing+and+treatment+among+men+who+have+sex+with+men+in+China%3A+a+qualitative+study&rft.au=Wei%2C+Chongyi%3BYan%2C+Hongjing%3BYang%2C+Chuankun%3BRaymond%2C+H+Fisher%3BLi%2C+Jianjun%3BYang%2C+Haitao%3BZhao%2C+Jinkou%3BHuan%2C+Xiping%3BStall%2C+Ron&rft.aulast=Wei&rft.aufirst=Chongyi&rft.date=2014-03-01&rft.volume=26&rft.issue=3&rft.spage=372&rft.isbn=&rft.btitle=&rft.title=AIDS+care&rft.issn=09540121&rft_id=info:doi/10.1080%2F09540121.2013.824538 LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2014-02-10 N1 - Last updated - 2014-02-18 N1 - SubjectsTermNotLitGenreText - 5703 3617 6220; 12258 11762 11859 11856; 10519 3279 971 3286; 5421 6091; 11565 5772 11538; 93 116 30 DO - http://dx.doi.org/10.1080/09540121.2013.824538 ER - TY - JOUR T1 - Epidemiologic Implications of Asymptomatic Reinfection: A Mathematical Modeling Study of Norovirus AN - 1505345638; 19324934 AB - The pathogenicity of norovirus is definitively established. However, norovirus is frequently detected in the stool of healthy individuals. To gain understanding of the apparent high prevalence of asymptomatic infection, we analyzed a dynamic transmission model of norovirus infection, disease, and immunity. We simulated norovirus epidemiology in low- and high-transmission settings by varying the basic reproduction number (R sub(0)). We predicted annual disease incidence values in children aged 0-4 years of 25% with a low R sub(0) and 29% with a high R sub(0). However, the point prevalence of asymptomatic infection rose sharply from 3% to 48% from the low to high R sub(0) settings. Among older children and adults, the models projected that incidence of disease would rise from 6% to 16% from the low to high R sub(0) settings, whereas asymptomatic infection prevalence was lower in this age group. Asymptomatic prevalence of norovirus can change dramatically with small changes in R sub(0). The ratio of prevalence in cases to controls could be high in a developed country and close to or even less than 1 in a high-exposure setting, despite similar disease incidence. These findings highlight an important limitation of case-control studies for pathogens for which there is suboptimal diagnostic specificity. JF - American Journal of Epidemiology AU - Lopman, Ben AU - Simmons, Kirsten AU - Gambhir, Manoj AU - Vinje, Jan AU - Parashar, Umesh AD - Correspondence to Dr. Ben Lopman, Division of Viral Diseases, National Center for Immunization and Respiratory Disease, Centers for Disease Control and Prevention, 1600 Clifton Road NE, MS-A34, Atlanta, GA 30333., blopman@cdc.gov Y1 - 2014/02/15/ PY - 2014 DA - 2014 Feb 15 SP - 507 EP - 512 PB - Oxford University Press, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 179 IS - 4 SN - 0002-9262, 0002-9262 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Developed countries KW - Age KW - Mathematical models KW - Norovirus KW - Asymptomatic infection KW - Pathogens KW - Immunity KW - Infection KW - Children KW - Epidemiology KW - Pathogenicity KW - Reproduction KW - Feces KW - H 12000:Epidemiology and Public Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1505345638?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Epidemiology&rft.atitle=Epidemiologic+Implications+of+Asymptomatic+Reinfection%3A+A+Mathematical+Modeling+Study+of+Norovirus&rft.au=Lopman%2C+Ben%3BSimmons%2C+Kirsten%3BGambhir%2C+Manoj%3BVinje%2C+Jan%3BParashar%2C+Umesh&rft.aulast=Lopman&rft.aufirst=Ben&rft.date=2014-02-15&rft.volume=179&rft.issue=4&rft.spage=507&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Epidemiology&rft.issn=00029262&rft_id=info:doi/10.1093%2Faje%2Fkwt287 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-03-01 N1 - Last updated - 2014-06-12 N1 - SubjectsTermNotLitGenreText - Age; Mathematical models; Pathogenicity; Epidemiology; Reproduction; Asymptomatic infection; Immunity; Pathogens; Feces; Children; Developed countries; Infection; Norovirus DO - http://dx.doi.org/10.1093/aje/kwt287 ER - TY - JOUR T1 - Does closure of children's medical home impact their immunization coverage? AN - 1660392426; PQ0001118517 AB - Little is known about the impact closing a health care facility has on immunization coverage of children utilizing that facility as a medical home. The authors assessed the impact of closing a Medicaid managed care facility in Philadelphia on immunization coverage of children, primarily low income children from racial/ethnic minority groups, utilizing that facility for routine immunizations. Immunization coverage declined at key age milestones for active clients of a Medicaid managed care that closed as compared with preclosure cohorts of clients from the same facility. When a primary health care facility closes, efforts should be made to ensure that children who had received vaccinations at that facility quickly establish a new medical home. JF - Public Health AU - Kolasa, M S AU - Stevenson, J AU - Ossa, A AU - Lutz, J AD - Health Services Research and Evaluation Branch, National Center for Immunization and Respiratory Disease, Centers for Disease Control and Prevention, 1600 Clifton Rd, A19, Atlanta, GA 30333, USA, mkolasa@cdc.gov PY - 2014 SP - 1106 EP - 1111 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 128 IS - 12 SN - 0033-3506, 0033-3506 KW - Health & Safety Science Abstracts KW - Immunization KW - Minority health KW - Children/adolescents KW - Health disparities KW - Health services KW - Age KW - USA, Pennsylvania, Philadelphia KW - Health care KW - Socioeconomics KW - Vaccines KW - Children KW - Minority groups KW - Income KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1660392426?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Public+Health&rft.atitle=Does+closure+of+children%27s+medical+home+impact+their+immunization+coverage%3F&rft.au=Kolasa%2C+M+S%3BStevenson%2C+J%3BOssa%2C+A%3BLutz%2C+J&rft.aulast=Kolasa&rft.aufirst=M&rft.date=2014-02-01&rft.volume=128&rft.issue=12&rft.spage=1106&rft.isbn=&rft.btitle=&rft.title=Public+Health&rft.issn=00333506&rft_id=info:doi/10.1016%2Fj.puhe.2014.08.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Last updated - 2015-12-23 N1 - SubjectsTermNotLitGenreText - Age; Health care; Socioeconomics; Vaccines; Children; Minority groups; Immunization; Income; USA, Pennsylvania, Philadelphia DO - http://dx.doi.org/10.1016/j.puhe.2014.08.002 ER - TY - JOUR T1 - Receipt of HIV/STD prevention counseling by HIV-infected adults receiving medical care in the United States AN - 1765969009; PQ0002559389 AB - Objective: Guidelines recommend risk-reduction counseling by HIV providers to all HIV-infected persons. Among HIV-infected adults receiving medical care in the United States, we estimated prevalence of exposure to three types of HIV/sexually transmitted disease (STD) risk-reduction interventions and described the characteristics of persons who received these interventions. Design: Data were from the Medical Monitoring Project (MMP), a supplemental HIV surveillance system designed to produce nationally representative estimates of behavioral and clinical characteristics of HIV-infected adults receiving medical care in the United States. Methods: Descriptive analyses were conducted to estimate the exposure to each type of HIV/STD risk-reduction intervention. Bivariate and multivariable analyses were conducted to assess associations between the selected correlates with each exposure variable. Results: About 44% of participants reported a one-on-one conversation with a healthcare provider about HIV/STD prevention, 30% with a prevention program worker, 16% reported participation in a small group risk-reduction intervention, and 52% reported receiving at least one of the three interventions in the past 12 months. Minority race/ethnicity, low income, and risky sexual behavior consistently predicted greater intervention exposure. However, 39% of persons who reported risky sex did not receive any HIV/STD risk-reduction interventions. Conclusions: HIV-infected persons in care with fewer resources or those who engaged in risk behaviors were more likely to receive HIV/STD risk-reduction interventions. However, less than half of HIV-infected persons in care received HIV/STD prevention counseling from their provider, an intervention that has been shown to be effective and is supported by guidelines. JF - AIDS AU - Mizuno, Yuko AU - Zhu, Julia AU - Crepaz, Nicole AU - Beer, Linda AU - Purcell, David W AU - Johnson, Christopher H AU - Valverde, Eduardo E AU - Skarbinski, Jacek AD - Division of HIV/AIDS Prevention, The U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, USA, ymizuno@cdc.gov Y1 - 2014/01/28/ PY - 2014 DA - 2014 Jan 28 SP - 407 EP - 415 PB - Lippincott Williams & Wilkins, Inc, 530 Walnut Street Philadelphia PA 19106-3621 United States VL - 28 IS - 3 SN - 0269-9370, 0269-9370 KW - Health & Safety Science Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - HIV/sexually transmitted disease prevention counseling KW - HIV-infected persons KW - Medical Monitoring Project KW - Risk assessment KW - Acquired immune deficiency syndrome KW - Data processing KW - Sexually-transmitted diseases KW - Guidelines KW - Risk taking KW - Intervention KW - Risk reduction KW - Sexual behavior KW - Medical personnel KW - Workers KW - USA KW - Prevention KW - Behavior KW - Human immunodeficiency virus KW - Occupational exposure KW - Sexually transmitted diseases KW - Races KW - Ethnic groups KW - Sex KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1765969009?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS&rft.atitle=Receipt+of+HIV%2FSTD+prevention+counseling+by+HIV-infected+adults+receiving+medical+care+in+the+United+States&rft.au=Mizuno%2C+Yuko%3BZhu%2C+Julia%3BCrepaz%2C+Nicole%3BBeer%2C+Linda%3BPurcell%2C+David+W%3BJohnson%2C+Christopher+H%3BValverde%2C+Eduardo+E%3BSkarbinski%2C+Jacek&rft.aulast=Mizuno&rft.aufirst=Yuko&rft.date=2014-01-28&rft.volume=28&rft.issue=3&rft.spage=407&rft.isbn=&rft.btitle=&rft.title=AIDS&rft.issn=02699370&rft_id=info:doi/10.1097%2FQAD.0000000000000057 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Workers; Data processing; Sexually-transmitted diseases; Sexual behavior; Ethnic groups; Races; Sex; Risk assessment; Acquired immune deficiency syndrome; Guidelines; Intervention; Risk taking; Risk reduction; Medical personnel; Prevention; Behavior; Human immunodeficiency virus; Sexually transmitted diseases; Occupational exposure; USA DO - http://dx.doi.org/10.1097/QAD.0000000000000057 ER - TY - JOUR T1 - Disparities in HIV transmission risk among HIV-infected black and white men who have sex with men, United States, 2009 AN - 1768579447; PQ0002676669 AB - Objective: To better understand why HIV incidence is substantially higher among black than white men who have sex with men (MSM), we present the first nationally representative estimates of factors that contribute to transmission - sexual behavior, antiretroviral therapy (ART) use, and viral suppression - among HIV-infected black and white MSM in the United States. Design: The Medical Monitoring Project (MMP) is a complex sample survey of HIV-infected adults receiving medical care in the United States. Methods: We used weighted interview and medical record data collected during June 2009 to May 2010 to estimate the prevalence of sexual behaviors, ART use, and viral suppression among sexually active HIV-infected black and white MSM. We used chi super(2) tests to assess significant differences between races and logistic regression models to identify factors that mediated the racial differences. Results: Sexual risk behaviors among black and white MSM were similar. Black MSM were significantly less likely than white MSM to take ART (80 vs. 91%) and be durably virally suppressed (48 vs. 69%). Accounting for mediators (e.g. age, insurance, poverty, education, time since diagnosis, and disease stage) reduced, but did not eliminate, disparities in ART use and rendered differences in viral suppression among those on ART insignificant. Conclusion: Lower levels of ART use and viral suppression among HIV-infected black MSM may increase the likelihood of HIV transmission. Addressing the patient-level factors and structural inequalities that contribute to lower levels of ART use and viral suppression among this group will improve clinical outcomes and might reduce racial disparities in HIV incidence. JF - AIDS AU - Beer, Linda AU - Oster, Alexandra M AU - Mattson, Christine L AU - Skarbinski, Jacek AD - Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, LBeer@cdc.gov Y1 - 2014/01/02/ PY - 2014 DA - 2014 Jan 02 SP - 105 EP - 114 PB - Lippincott Williams & Wilkins, Inc, 530 Walnut Street Philadelphia PA 19106-3621 United States VL - 28 IS - 1 SN - 0269-9370, 0269-9370 KW - Health & Safety Science Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - antiretroviral therapy KW - health status disparities KW - men who have sex with men KW - surveillance KW - viral load KW - Risk assessment KW - Acquired immune deficiency syndrome KW - Age KW - Data processing KW - medical records KW - Homosexuality KW - Race differences KW - Antiretroviral agents KW - Insurance KW - Sexual behavior KW - Disease transmission KW - Models KW - USA KW - Education KW - Human immunodeficiency virus KW - Risk factors KW - Poverty KW - Regression analysis KW - Sex KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma KW - F 06910:Microorganisms & Parasites UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1768579447?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS&rft.atitle=Disparities+in+HIV+transmission+risk+among+HIV-infected+black+and+white+men+who+have+sex+with+men%2C+United+States%2C+2009&rft.au=Beer%2C+Linda%3BOster%2C+Alexandra+M%3BMattson%2C+Christine+L%3BSkarbinski%2C+Jacek&rft.aulast=Beer&rft.aufirst=Linda&rft.date=2014-01-02&rft.volume=28&rft.issue=1&rft.spage=105&rft.isbn=&rft.btitle=&rft.title=AIDS&rft.issn=02699370&rft_id=info:doi/10.1097%2FQAD.0000000000000021 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Age; Data processing; medical records; antiretroviral therapy; Regression analysis; Race differences; Sexual behavior; Models; Sex; Disease transmission; Risk assessment; Education; Acquired immune deficiency syndrome; Human immunodeficiency virus; Poverty; Risk factors; Homosexuality; Insurance; Antiretroviral agents; USA DO - http://dx.doi.org/10.1097/QAD.0000000000000021 ER - TY - JOUR T1 - Laboratory Identification of Arthropod Ectoparasites AN - 1753470249; 18996647 JF - Clinical Microbiology Reviews AU - Mathison, Blaine A AU - Pritt, Bobbi S AD - Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, gqa4@cdc.gov. PY - 2014 SP - 48 EP - 67 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 27 IS - 1 SN - 0893-8512, 0893-8512 KW - Microbiology Abstracts B: Bacteriology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1753470249?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+Microbiology+Reviews&rft.atitle=Laboratory+Identification+of+Arthropod+Ectoparasites&rft.au=Mathison%2C+Blaine+A%3BPritt%2C+Bobbi+S&rft.aulast=Mathison&rft.aufirst=Blaine&rft.date=2014-01-01&rft.volume=27&rft.issue=1&rft.spage=48&rft.isbn=&rft.btitle=&rft.title=Clinical+Microbiology+Reviews&rft.issn=08938512&rft_id=info:doi/10.1128%2FCMR.00008-13 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-01-01 N1 - Number of references - 139 N1 - Last updated - 2016-01-06 DO - http://dx.doi.org/10.1128/CMR.00008-13 ER - TY - JOUR T1 - Associations of Work Hours, Job Strain, and Occupation With Endothelial Function: The Multi-Ethnic Study of Atherosclerosis (MESA) AN - 1647025093; 21140802 AB - Objective: To investigate associations of work hours, job control, job demands, job strain, and occupational category with brachial artery flow-mediated dilation (FMD) in 1499 Multi-Ethnic Study of Atherosclerosis participants. Methods: Flow-mediated dilation was obtained using high-resolution ultrasound. Mean values of FMD were examined across categories of occupation, work hours, and the other exposures using regression analyses. Results: Occupational category was significantly associated with FMD overall, with blue-collar workers showing the lowest mean values- management/professional = 4.97 + or - 0.22%; sales/office = 5.19 + or - 0.28%; services = 4.73 + or - 0.29%; and blue-collar workers = 4.01 + or - 0.26% (adjusted P < 0.001). There was evidence of effect modification by sex (interaction P = 0.031)-significant associations were observed among women (adjusted P = 0.002) and nearly significant results among men (adjusted P = 0.087). Other exposures were not significantly associated with FMD. Conclusions: Differences in endothelial function may account for some of the variation in cardiovascular disease across occupational groups. JF - Journal of Occupational and Environmental Medicine AU - Charles, Luenda E AU - Fekedulegn, Desta AU - Landsbergis, Paul AU - Burchfiel, Cecil M AU - Baron, Sherry AU - Kaufman, Joel D AU - Stukovsky, Karen Hinckley AU - Fujishiro, Kaori AU - Foy, Capri G AU - Andrew, Michael E AU - Roux, Ana V Diez AD - Biostatistics and Epidemiology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, HELD/BEB, MS L-4050, 1095 Willowdale Rd, Morgantown, WV 26505, lcharles@cdc.gov PY - 2014 SP - 1153 EP - 1160 PB - Williams & Wilkins, 351 W. Camden St. Baltimore MD 21201 United States VL - 56 IS - 11 SN - 1076-2752, 1076-2752 KW - Health & Safety Science Abstracts KW - Mesas KW - Cardiovascular diseases KW - Working conditions KW - Occupational health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1647025093?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Associations+of+Work+Hours%2C+Job+Strain%2C+and+Occupation+With+Endothelial+Function%3A+The+Multi-Ethnic+Study+of+Atherosclerosis+%28MESA%29&rft.au=Charles%2C+Luenda+E%3BFekedulegn%2C+Desta%3BLandsbergis%2C+Paul%3BBurchfiel%2C+Cecil+M%3BBaron%2C+Sherry%3BKaufman%2C+Joel+D%3BStukovsky%2C+Karen+Hinckley%3BFujishiro%2C+Kaori%3BFoy%2C+Capri+G%3BAndrew%2C+Michael+E%3BRoux%2C+Ana+V+Diez&rft.aulast=Charles&rft.aufirst=Luenda&rft.date=2014-01-01&rft.volume=56&rft.issue=11&rft.spage=1153&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0000000000000311 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2015-12-23 N1 - SubjectsTermNotLitGenreText - Mesas; Cardiovascular diseases; Working conditions; Occupational health DO - http://dx.doi.org/10.1097/JOM.0000000000000311 ER - TY - JOUR T1 - Lack of Evidence of Increased West Nile Virus Disease Severity in the United States in 2012 AN - 1647020637; 21172709 AB - In the United States, West Nile virus (WNV) causes annual seasonal outbreaks that fluctuate in size and scope. There was a large multistate outbreak of WNV in 2012, with more human disease cases reported nationally than any year since 2003. We evaluated national surveillance data to determine if the higher number of WNV cases reported in 2012 was associated with changes in the epidemiology or severity of disease compared with 2004-2011. Despite an increased incidence of neuroinvasive disease in 2012, national surveillance data showed no evidence of changes in epidemiology or increased disease severity compared with the previous 8 years. JF - American Journal of Tropical Medicine and Hygiene AU - Lindsey, Nicole P AU - Staples, J Erin AU - Delorey, Mark J AU - Fischer, Marc AD - Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, 3156 Rampart Road, Fort Collins, CO 80521, frd3@cdc.gov Y1 - 2014/01// PY - 2014 DA - January 2014 SP - 163 EP - 168 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 90 IS - 1 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts KW - Invasiveness KW - Human diseases KW - Data processing KW - Surveillance and enforcement KW - Public health KW - USA KW - Sulfur dioxide KW - Epidemiology KW - Outbreaks KW - Hygiene KW - Seasonal variations KW - West Nile virus KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - V 22490:Miscellaneous KW - K 03400:Human Diseases KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08502:Methods and instruments KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1647020637?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Lack+of+Evidence+of+Increased+West+Nile+Virus+Disease+Severity+in+the+United+States+in+2012&rft.au=Lindsey%2C+Nicole+P%3BStaples%2C+J+Erin%3BDelorey%2C+Mark+J%3BFischer%2C+Marc&rft.aulast=Lindsey&rft.aufirst=Nicole&rft.date=2014-01-01&rft.volume=90&rft.issue=1&rft.spage=163&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.13-0432 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Human diseases; Epidemiology; Surveillance and enforcement; Hygiene; Public health; Invasiveness; Data processing; Sulfur dioxide; Outbreaks; Seasonal variations; West Nile virus; USA DO - http://dx.doi.org/10.4269/ajtmh.13-0432 ER - TY - JOUR T1 - Outbreaks of non-O157 Shiga toxin-producing Escherichia coli infection: USA AN - 1618149429; 20811031 AB - Non-O157 Shiga toxin-producing Escherichia coli (STEC) infections are increasingly detected, but sources are not well established. We summarize outbreaks to 2010 in the USA. Single-aetiology outbreaks were defined as 2 epidemiologically linked culture-confirmed non-O157 STEC infections; multiple-aetiology outbreaks also had laboratory evidence of 2 infections caused by another enteric pathogen. Twenty-six states reported 46 outbreaks with 1727 illnesses and 144 hospitalizations. Of 38 single-aetiology outbreaks, 66% were caused by STEC O111 (n = 14) or O26 (n = 11), and 84% were transmitted through food (n = 17) or person-to-person spread (n = 15); food vehicles included dairy products, produce, and meats; childcare centres were the most common setting for person-to-person spread. Of single-aetiology outbreaks, a greater percentage of persons infected by Shiga toxin 2-positive strains had haemolytic uraemic syndrome compared with persons infected by Shiga toxin 1-only positive strains (7% vs. 0.8%). Compared with single-aetiology outbreaks, multiple-aetiology outbreaks were more frequently transmitted through water or animal contact. JF - Epidemiology and Infection AU - Luna-Gierke, R E AU - Griffin, P M AU - Gould, L H AU - Herman, K AU - Bopp, CA AU - STROCKBINE, N AU - Mody, R K AD - Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA, RGierke@cdc.gov PY - 2014 SP - 2270 EP - 2280 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 142 IS - 11 SN - 0950-2688, 0950-2688 KW - Microbiology Abstracts B: Bacteriology KW - Meat KW - Food KW - Reviews KW - Escherichia coli KW - Dairy products KW - Pathogens KW - Infection KW - Shiga toxin KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1618149429?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Outbreaks+of+non-O157+Shiga+toxin-producing+Escherichia+coli+infection%3A+USA&rft.au=Luna-Gierke%2C+R+E%3BGriffin%2C+P+M%3BGould%2C+L+H%3BHerman%2C+K%3BBopp%2C+CA%3BSTROCKBINE%2C+N%3BMody%2C+R+K&rft.aulast=Luna-Gierke&rft.aufirst=R&rft.date=2014-01-01&rft.volume=142&rft.issue=11&rft.spage=2270&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268813003233 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-10-01 N1 - Number of references - 35 N1 - Last updated - 2016-01-21 N1 - SubjectsTermNotLitGenreText - Meat; Reviews; Food; Dairy products; Pathogens; Infection; Shiga toxin; Escherichia coli DO - http://dx.doi.org/10.1017/S0950268813003233 ER - TY - JOUR T1 - Determination of urine caffeine and its metabolites by use of high-performance liquid chromatography-tandem mass spectrometry: estimating dietary caffeine exposure and metabolic phenotyping in population studies AN - 1551043890; 19974688 AB - We have developed and validated a high-performance liquid chromatography-tandem mass spectrometric (LC-MS/MS) method for determining urine caffeine and 14 caffeine metabolites suitable for estimating caffeine exposure and metabolic phenotyping in population studies. Sample preparation consisted solely of a series of simple reagent treatments at room temperature. Stable isotope-labeled analogs were used as internal standards for all analytes. We developed rapid LC-MS/MS separations for both positive and negative ion mode electrospray ionizations to maximize measurement sensitivity. Limits of detection were 0.05-0.1 [mu]mol/L depending on the analytes. Method imprecision, based on total coefficients of variation, was generally 1 [mu]mol/L. Analyte recoveries were typically within 10 % of being quantitative (100 %), and good agreement was observed among analytes measured across different MS/MS transitions. We applied this method to the analysis of a convenience set of human urine samples (n = 115) and were able to detect a majority of the analytes in [> or =]99 % of samples as well as calculate caffeine metabolite phenotyping ratios for cytochrome P450 1A2 and N-acetyltransferase 2. Whereas existing LC-MS/MS methods are limited in number of caffeine metabolites for which they are validated, or are designed for studies in which purposely elevated caffeine levels are expected, our method is the first of its kind designed specifically for the rapid, sensitive, accurate, and precise measurement of urine caffeine and caffeine metabolites at concentrations relevant to population studies. JF - Analytical and Bioanalytical Chemistry AU - Rybak, Michael E AU - Pao, Ching-I AU - Pfeiffer, Christine M AD - U.S. Centers for Disease Control and Prevention, National Center for Environmental Health, 4770 Buford Highway, MS F-55, Atlanta, GA 30341, USA, MRybak@cdc.gov PY - 2014 SP - 771 EP - 784 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 406 IS - 3 SN - 1618-2642, 1618-2642 KW - Aqualine Abstracts; Water Resources Abstracts KW - Caffeine KW - Urine KW - Biomarkers KW - Dietary intake KW - Phenotyping KW - Mass spectrometry KW - NHANES KW - Reagents KW - Mass Spectrometry KW - Estimating KW - Metabolites KW - Sample Preparation KW - Exposure KW - Standards KW - Ionization KW - AQ 00001:Water Resources and Supplies KW - SW 0810:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1551043890?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytical+and+Bioanalytical+Chemistry&rft.atitle=Determination+of+urine+caffeine+and+its+metabolites+by+use+of+high-performance+liquid+chromatography-tandem+mass+spectrometry%3A+estimating+dietary+caffeine+exposure+and+metabolic+phenotyping+in+population+studies&rft.au=Rybak%2C+Michael+E%3BPao%2C+Ching-I%3BPfeiffer%2C+Christine+M&rft.aulast=Rybak&rft.aufirst=Michael&rft.date=2014-01-01&rft.volume=406&rft.issue=3&rft.spage=771&rft.isbn=&rft.btitle=&rft.title=Analytical+and+Bioanalytical+Chemistry&rft.issn=16182642&rft_id=info:doi/10.1007%2Fs00216-013-7506-9 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-12-01 N1 - Number of references - 47 N1 - Last updated - 2016-01-21 N1 - SubjectsTermNotLitGenreText - Mass Spectrometry; Sample Preparation; Reagents; Urine; Estimating; Exposure; Standards; Metabolites; Ionization DO - http://dx.doi.org/10.1007/s00216-013-7506-9 ER - TY - JOUR T1 - Workplace Hazards and Prevention Options From a Nonrandom Sample of Retail Trade Businesses AN - 1544001330; 20178221 AB - Employer commitment is a key factor in an effective safety program, yet limited research has focused on the safety priorities of retail store managers. To address this, the U.S. National Institute for Occupational Safety and Health recruited 4 experienced ergonomists, who met and interviewed 9 retailers in different parts of the eastern USA. The reports from the 9 interviews were used to document the hazards facing retailers and the interventions they attempted. Those interviewed were managers/owners of establishments that ranged from a small bakery with 11 employees to a supermarket with 85 or more employees. The main hazards across all establishments included overexertion, contact-with-objects, and falls-to-the-same-level. We also compared the retailers' perceptions of safety hazards with injuries from actual hazards as supplied by the U.S. Bureau of Labor Statistics. This report provides insight into the retailers' perceptions of safety hazards as well as their commitment to the prevention of workplace injuries. JF - International Journal of Occupational Safety and Ergonomics AU - Anderson, Vern Putz AU - Chun, Heekyoung AD - National Institute for Occupational Safety and Health (NIOSH) 4676 Columbia Pwky, Cincinnati, Ohio 45226, USA, vepl@cdc.gov Y1 - 2014 PY - 2014 DA - 2014 SP - 181 EP - 195 PB - Central Institute for Labour Protection - National Research Institute (CIOP-PIB), 16 Czerniakowska str. VL - 20 IS - 1 SN - 1080-3548, 1080-3548 KW - Health & Safety Science Abstracts KW - hazards KW - interventions KW - engineering controls KW - ergonomics KW - manual materials handling KW - Hazards KW - USA KW - Prevention KW - Injuries KW - Trade KW - Perception KW - Safety KW - Occupational safety KW - Intervention KW - Priorities KW - Ergonomics KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1544001330?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Occupational+Safety+and+Ergonomics&rft.atitle=Workplace+Hazards+and+Prevention+Options+From+a+Nonrandom+Sample+of+Retail+Trade+Businesses&rft.au=Anderson%2C+Vern+Putz%3BChun%2C+Heekyoung&rft.aulast=Anderson&rft.aufirst=Vern&rft.date=2014-01-01&rft.volume=20&rft.issue=1&rft.spage=181&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Occupational+Safety+and+Ergonomics&rft.issn=10803548&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-07-01 N1 - Last updated - 2015-04-16 N1 - SubjectsTermNotLitGenreText - Hazards; Prevention; Trade; Injuries; Perception; Occupational safety; Safety; Priorities; Intervention; Ergonomics; USA ER - TY - JOUR T1 - Incorporating Couples-Based Approaches into HIV Prevention for Gay and Bisexual Men: Opportunities and Challenges AN - 1516764918; 18976087 AB - Thirty years after the beginning of the HIV epidemic, gay, bisexual, and other men who have sex with men (collectively called MSM) bear a disproportionate burden of HIV in the United States and continue to acquire a distressingly high number and proportion of new infections. Historically, HIV prevention for MSM has been focused on individual-level behavior change, rarely intervening with MSM as part of a couple. Yet, an estimated 33-67 % of HIV infections among MSM are acquired from primary sexual partners, suggesting that work with MSM as couples could be an important contributor to prevention. Given the emergence of high impact combination HIV prevention, it is timely to consider how work with the broad variety of male couples can improve both personal and community health. Couples HIV testing and counseling for MSM is an important advance for identifying men who are unaware that they are HIV-positive, identifying HIV-discordant couples, and supporting men who want to learn their HIV status with their partner. Once men know their HIV status, new advances in biomedical prevention, which can dramatically reduce risk of HIV transmission or acquisition, allow men to make prevention decisions that can protect themselves and their partners. This paper highlights the present-day challenges and benefits of using a couples-based approach with MSM in the era of combination prevention to increase knowledge of HIV status, increase identification of HIV discordant couples to improve targeting prevention services, and support mutual disclosure of HIV status. JF - Archives of Sexual Behavior AU - Purcell, David W AU - Mizuno, Yuko AU - Smith, Dawn K AU - Grabbe, Kristina AU - Courtenay-Quirk, Cari AU - Tomlinson, Hank AU - Mermin, Jonathan AD - Division of HIV/AIDS Prevention (MS D-21), Centers for Disease Prevention and Control, 1600 Clifton Road, Atlanta, GA, 30333, USA, dhp8@cdc.gov Y1 - 2014/01// PY - 2014 DA - Jan 2014 SP - 35 EP - 46 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 43 IS - 1 SN - 0004-0002, 0004-0002 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Historical account KW - USA KW - Prevention KW - Human immunodeficiency virus KW - Bisexuality KW - Males KW - Homosexuality KW - Risk reduction KW - Infection KW - Sexual behavior KW - Disease transmission KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1516764918?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Archives+of+Sexual+Behavior&rft.atitle=Incorporating+Couples-Based+Approaches+into+HIV+Prevention+for+Gay+and+Bisexual+Men%3A+Opportunities+and+Challenges&rft.au=Purcell%2C+David+W%3BMizuno%2C+Yuko%3BSmith%2C+Dawn+K%3BGrabbe%2C+Kristina%3BCourtenay-Quirk%2C+Cari%3BTomlinson%2C+Hank%3BMermin%2C+Jonathan&rft.aulast=Purcell&rft.aufirst=David&rft.date=2014-01-01&rft.volume=43&rft.issue=1&rft.spage=35&rft.isbn=&rft.btitle=&rft.title=Archives+of+Sexual+Behavior&rft.issn=00040002&rft_id=info:doi/10.1007%2Fs10508-013-0205-y LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-04-01 N1 - Number of references - 104 N1 - Last updated - 2014-05-29 N1 - SubjectsTermNotLitGenreText - Historical account; Prevention; Human immunodeficiency virus; Males; Bisexuality; Risk reduction; Homosexuality; Infection; Sexual behavior; Disease transmission; USA DO - http://dx.doi.org/10.1007/s10508-013-0205-y ER - TY - JOUR T1 - Use of the CDC Autocidal Gravid Ovitrap to Control and Prevent Outbreaks of Aedes aegypti (Diptera: Culicidae) AN - 1500767740; 19157908 AB - Populations of Aedes aegypti (L.) can be managed through reductions in adult mosquito survival, number of offspring produced, or both. Direct adult mortality can be caused by the use of space sprays or residual insecticides to mosquito resting sites, and with a variety of residual insecticideimpregnated surfaces that are being tested, such as curtains, covers for water-storage vessels, bednets, and ovitraps. The fertility of Ae. aegypti populations can be reduced by the use of autocidal oviposition cups that prevent the development of mosquitoes inside the trap by mechanical means or larvicides, as well as by releasing sterile, transgenic, and para-transgenic mosquitoes. Survival and fertility can be simultaneously reduced by capturing gravid female Ae. aegypti with sticky gravid traps. We tested the effectiveness of the novel Centers for Disease Control and Prevention autocidal gravid ovitrap (CDC-AGO trap) to control natural populations of Ae. aegypti under field conditions in two isolated urban areas (reference vs. intervention areas) in southern Puerto Rico for 1 yr. There were significant reductions in the captures of female Ae. aegypti (53-70%) in the intervention area. The presence of three to four AGO control traps per home in 81% of the houses prevented outbreaks of Ae. aegypti , which would be expected after rains. Mosquito captures in BG-Sentinel and AGO traps were significantly and positively correlated, showing that AGO traps are useful and inexpensive mosquito surveillance devices. The use of AGO traps to manage Ae. aegypti populations is compatible with other control means such as source reduction, larviciding, adulticiding, sterile insect techniques, induced cytoplasmic incompatibility, and dominant lethal gene systems. JF - Journal of Medical Entomology AU - Barrera, Roberto AU - Amador, Manuel AU - Acevedo, Veronica AU - Caban, Belkis AU - Felix, Gilberto AU - Mackay, Andrew J AD - Entomology and Ecology Activity, Dengue Branch, Centers for Disease Control and Prevention, 1324 Calle Canada, San Juan, PR 00920, rbarrera@cdc.gov Y1 - 2014 PY - 2014 DA - 2014 SP - 145 EP - 154 PB - Entomological Society of America, 9301 Annapolis Rd. Lanham MD 20706 United States VL - 51 IS - 1 SN - 0022-2585, 0022-2585 KW - Health & Safety Science Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Entomology Abstracts KW - Aedes aegypti KW - vector control KW - mosquito trap KW - dengue KW - outbreak KW - Fertility KW - Housing KW - Disease control KW - Intervention KW - Survival KW - Offspring KW - Insecticides KW - Natural populations KW - Aquatic insects KW - Biological surveys KW - Mortality KW - Houses KW - Sprays KW - Larvae KW - Culicidae KW - Pest control KW - Pest outbreaks KW - Insects KW - Prevention KW - Cytoplasmic incompatibility KW - ASW, Caribbean Sea, Greater Antilles, Puerto Rico KW - Spray KW - Pesticides KW - Residential areas KW - Progeny KW - Outbreaks KW - Rain KW - Diptera KW - Oviposition KW - Larvicides KW - Mortality causes KW - Q1 08485:Species interactions: pests and control KW - Q5 08524:Public health, medicines, dangerous organisms KW - H 0500:General KW - Z 05330:Reproduction and Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1500767740?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Medical+Entomology&rft.atitle=Use+of+the+CDC+Autocidal+Gravid+Ovitrap+to+Control+and+Prevent+Outbreaks+of+Aedes+aegypti+%28Diptera%3A+Culicidae%29&rft.au=Barrera%2C+Roberto%3BAmador%2C+Manuel%3BAcevedo%2C+Veronica%3BCaban%2C+Belkis%3BFelix%2C+Gilberto%3BMackay%2C+Andrew+J&rft.aulast=Barrera&rft.aufirst=Roberto&rft.date=2014-01-01&rft.volume=51&rft.issue=1&rft.spage=145&rft.isbn=&rft.btitle=&rft.title=Journal+of+Medical+Entomology&rft.issn=00222585&rft_id=info:doi/10.1603%2FME12131 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-02-01 N1 - Number of references - 38 N1 - Last updated - 2014-12-11 N1 - SubjectsTermNotLitGenreText - Biological surveys; Fertility; Spray; Pesticides; Larvae; Survival; Pest control; Aquatic insects; Mortality causes; Mortality; Houses; Insecticides; Cytoplasmic incompatibility; Disease control; Progeny; Rain; Pest outbreaks; Oviposition; Larvicides; Housing; Sprays; Intervention; Offspring; Insects; Prevention; Residential areas; Natural populations; Outbreaks; Aedes aegypti; Culicidae; Diptera; ASW, Caribbean Sea, Greater Antilles, Puerto Rico DO - http://dx.doi.org/10.1603/ME12131 ER - TY - JOUR T1 - Occupational safety and health criteria for responsible development of nanotechnology AN - 1496885869; 19009061 AB - Organizations around the world have called for the responsible development of nanotechnology. The goals of this approach are to emphasize the importance of considering and controlling the potential adverse impacts of nanotechnology in order to develop its capabilities and benefits. A primary area of concern is the potential adverse impact on workers, since they are the first people in society who are exposed to the potential hazards of nanotechnology. Occupational safety and health criteria for defining what constitutes responsible development of nanotechnology are needed. This article presents five criterion actions that should be practiced by decision-makers at the business and societal levels-if nanotechnology is to be developed responsibly. These include (1) anticipate, identify, and track potentially hazardous nanomaterials in the workplace; (2) assess workers' exposures to nanomaterials; (3) assess and communicate hazards and risks to workers; (4) manage occupational safety and health risks; and (5) foster the safe development of nanotechnology and realization of its societal and commercial benefits. All these criteria are necessary for responsible development to occur. Since it is early in the commercialization of nanotechnology, there are still many unknowns and concerns about nanomaterials. Therefore, it is prudent to treat them as potentially hazardous until sufficient toxicology, and exposure data are gathered for nanomaterial-specific hazard and risk assessments. In this emergent period, it is necessary to be clear about the extent of uncertainty and the need for prudent actions. JF - Journal of Nanoparticle Research AU - Schulte, P A AU - Geraci, CL AU - Murashov, V AU - Kuempel, ED AU - Zumwalde, R D AU - Castranova, V AU - Hoover, MD AU - Hodson, L AU - Martinez, K F AD - National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, 4676 Columbia Parkway, MS C-14, Cincinnati, OH, 45226, USA, pschulte@cdc.gov Y1 - 2014/01// PY - 2014 DA - Jan 2014 SP - 1 EP - 17 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 16 IS - 1 SN - 1388-0764, 1388-0764 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Risk assessment KW - Health risks KW - Risk management KW - Occupational safety KW - Occupational exposure KW - Toxicology KW - Nanotechnology KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1496885869?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Nanoparticle+Research&rft.atitle=Occupational+safety+and+health+criteria+for+responsible+development+of+nanotechnology&rft.au=Schulte%2C+P+A%3BGeraci%2C+CL%3BMurashov%2C+V%3BKuempel%2C+ED%3BZumwalde%2C+R+D%3BCastranova%2C+V%3BHoover%2C+MD%3BHodson%2C+L%3BMartinez%2C+K+F&rft.aulast=Schulte&rft.aufirst=P&rft.date=2014-01-01&rft.volume=16&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Journal+of+Nanoparticle+Research&rft.issn=13880764&rft_id=info:doi/10.1007%2Fs11051-013-2153-9 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-02-01 N1 - Number of references - 165 N1 - Last updated - 2015-03-20 N1 - SubjectsTermNotLitGenreText - Risk assessment; Risk management; Health risks; Occupational safety; Toxicology; Occupational exposure; Nanotechnology DO - http://dx.doi.org/10.1007/s11051-013-2153-9 ER - TY - JOUR T1 - A Novel Cytotoxic Sequence Contributes to Influenza A Viral Protein PB1-F2 Pathogenicity and Predisposition to Secondary Bacterial Infection AN - 1492645490; 18953933 AB - Enhancement of cell death is a distinguishing feature of H1N1 influenza virus A/Puerto Rico/8/34 protein PB1-F2. Comparing the sequences (amino acids [aa] 61 to 87 using PB1-F2 amino acid numbering) of the PB1-F2-derived C-terminal peptides from influenza A viruses inducing high or low levels of cell death, we identified a unique I68, L69, and V70 motif in A/Puerto Rico/8/34 PB1-F2 responsible for promotion of the peptide's cytotoxicity and permeabilization of the mitochondrial membrane. When administered to mice, a 27-mer PB1-F2-derived C-terminal peptide with this amino acid motif caused significantly greater weight loss and pulmonary inflammation than the peptide without it (due to I68T, L69Q, and V70G mutations). Similar to the wild-type peptide, A/Puerto Rico/8/34 elicited significantly higher levels of macrophages, neutrophils, and cytokines in the bronchoalveolar lavage fluid of mice than its mutant counterpart 7 days after infection. Additionally, infection of mice with A/Puerto Rico/8/34 significantly enhanced the levels of morphologically transformed epithelial and immune mononuclear cells recruited in the airways compared with the mutant virus. In the mouse bacterial superinfection model, both peptide and virus with the I68, L69, and V70 sequence accelerated development of pneumococcal pneumonia, as reflected by increased levels of viral and bacterial lung titers and by greater mortality. Here we provide evidence suggesting that the newly identified cytotoxic sequence I68, L69, and V70 of A/Puerto Rico/8/34 PB1-F2 contributes to the pathogenesis of both primary viral and secondary bacterial infections. JF - Journal of Virology AU - Alymova, Irina V AU - Samarasinghe, Amali AU - Vogel, Peter AU - Green, Amanda M AU - Weinlich, Ricardo AU - McCullers, Jonathan A AD - Influenza Division, National Center for Immunization & Respiratory Diseases, Centers for Disease Control & Prevention, Atlanta, Georgia, USA, ialymova@cdc.gov. Y1 - 2014/01// PY - 2014 DA - Jan 2014 SP - 503 EP - 515 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 88 IS - 1 SN - 0022-538X, 0022-538X KW - Health & Safety Science Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts KW - Macrophages KW - Influenza A KW - Viruses KW - Animal models KW - Mitochondria KW - Infection KW - Mutants KW - Influenza KW - Bronchus KW - Pathogenicity KW - Influenza A virus KW - Cytokines KW - Respiratory tract KW - Bacteria KW - Mortality KW - Leukocytes (mononuclear) KW - Membranes KW - Amino acids KW - Leukocytes (neutrophilic) KW - Mice KW - Superinfection KW - Alveoli KW - Inflammation KW - Streptococcus pneumoniae KW - Cell death KW - Cytotoxicity KW - ASW, Caribbean Sea, Greater Antilles, Puerto Rico KW - Lung KW - Proteins KW - Mutation KW - Pneumonia KW - J 02410:Animal Diseases KW - V 22410:Animal Diseases KW - A 01310:Products of Microorganisms KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1492645490?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Virology&rft.atitle=A+Novel+Cytotoxic+Sequence+Contributes+to+Influenza+A+Viral+Protein+PB1-F2+Pathogenicity+and+Predisposition+to+Secondary+Bacterial+Infection&rft.au=Alymova%2C+Irina+V%3BSamarasinghe%2C+Amali%3BVogel%2C+Peter%3BGreen%2C+Amanda+M%3BWeinlich%2C+Ricardo%3BMcCullers%2C+Jonathan+A&rft.aulast=Alymova&rft.aufirst=Irina&rft.date=2014-01-01&rft.volume=88&rft.issue=1&rft.spage=503&rft.isbn=&rft.btitle=&rft.title=Journal+of+Virology&rft.issn=0022538X&rft_id=info:doi/10.1128%2FJVI.01373-13 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-01-01 N1 - Number of references - 34 N1 - Last updated - 2015-04-02 N1 - SubjectsTermNotLitGenreText - Macrophages; Leukocytes (mononuclear); Mortality; Amino acids; Influenza A; Leukocytes (neutrophilic); Animal models; Mitochondria; Superinfection; Alveoli; Inflammation; Cytotoxicity; Cell death; Pathogenicity; Bronchus; Lung; Cytokines; Mutation; Pneumonia; Respiratory tract; Influenza; Membranes; Viruses; Proteins; Mice; Infection; Mutants; Bacteria; Streptococcus pneumoniae; Influenza A virus; ASW, Caribbean Sea, Greater Antilles, Puerto Rico DO - http://dx.doi.org/10.1128/JVI.01373-13 ER - TY - JOUR T1 - Impact of medical and behavioural factors on influenza-like illness, healthcare-seeking, and antiviral treatment during the 2009 H1N1 pandemic: USA, 2009-2010 AN - 1492634881; 18889466 AB - We analysed a cross-sectional telephone survey of U.S. adults to assess the impact of selected characteristics on healthcare-seeking behaviours and treatment practices of people with influenza-like illness (ILI) from September 2009 to March 2010. Of 216 431 respondents, 8.1% reported ILI. After adjusting for selected characteristics, respondents aged 18-64 years with the following factors were more likely to report ILI: a diagnosis of asthma [adjusted odds ratio (aOR) 1.88, 95% CI 1.67-2.13] or heart disease (aOR 1.41, 95% CI 1.17-1.70), being disabled (aOR 1.75, 95% CI 1.57-1.96), and reporting financial barriers to healthcare access (aOR 1.63, 95% CI 1.45-1.82). Similar associations were seen in respondents aged 65 years. Forty percent of respondents with ILI sought healthcare, and 14% who sought healthcare reported receiving influenza antiviral treatment. Treatment was not more frequent in patients with high-risk conditions, except those aged 18-64 years with heart disease (aOR 1.90, 95% CI 1.03-3.51). Of patients at high risk for influenza complications, self-reported ILI was greater but receipt of antiviral treatment was not, despite guidelines recommending their use in this population. JF - Epidemiology and Infection AU - Biggerstaff, M AU - JHUNG, MA AU - Reed, C AU - Garg, S AU - Balluz, L AU - Fry, A M AU - Finelli, L AD - Epidemiology and Prevention Branch, Influenza Division, National Center for Immunization and Respiratory Disease, Centers for Disease Control and Prevention, Atlanta, GA, USA, MBiggerstaff@cdc.gov Y1 - 2014/01// PY - 2014 DA - Jan 2014 SP - 114 EP - 125 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 142 IS - 1 SN - 0950-2688, 0950-2688 KW - Risk Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology; Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Risk assessment KW - Complications KW - Guidelines KW - Asthma KW - Respiratory diseases KW - Influenza KW - USA KW - pandemics KW - Health care KW - Risk factors KW - Risk groups KW - Heart diseases KW - A 01340:Antibiotics & Antimicrobials KW - R2 23060:Medical and environmental health KW - H 12000:Epidemiology and Public Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1492634881?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Impact+of+medical+and+behavioural+factors+on+influenza-like+illness%2C+healthcare-seeking%2C+and+antiviral+treatment+during+the+2009+H1N1+pandemic%3A+USA%2C+2009-2010&rft.au=Biggerstaff%2C+M%3BJHUNG%2C+MA%3BReed%2C+C%3BGarg%2C+S%3BBalluz%2C+L%3BFry%2C+A+M%3BFinelli%2C+L&rft.aulast=Biggerstaff&rft.aufirst=M&rft.date=2014-01-01&rft.volume=142&rft.issue=1&rft.spage=114&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268813000654 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-12-01 N1 - Number of references - 35 N1 - Last updated - 2015-04-02 N1 - SubjectsTermNotLitGenreText - Influenza; pandemics; Risk factors; Asthma; Risk groups; Heart diseases; Risk assessment; Health care; Complications; Guidelines; Respiratory diseases; USA DO - http://dx.doi.org/10.1017/S0950268813000654 ER - TY - JOUR T1 - Surveillance during an era of rapidly changing poliovirus epidemiology in India: the role of one vs. two stool specimens in poliovirus detection, 2000-2010 AN - 1492632472; 18889468 AB - Since 2004, efforts to improve poliovirus detection have significantly increased the volume of specimen testing from acute flaccid paralysis (AFP) patients in India. One option to decrease collection and testing burden would be collecting only a single stool specimen instead of two. We investigated stool specimen sensitivity for poliovirus detection in India to estimate the contribution of the second specimen. We reviewed poliovirus isolation data for 303984 children aged <15 years with AFP during 2000-2010. Using maximum-likelihood estimation, we determined specimen sensitivity of each stool specimen, combined sensitivity of both specimens, and sensitivity added by the second specimen. Of 5184 AFP patients with poliovirus isolates, 382 (7.4%) were identified only by the second specimen. Sensitivity was 91.4% for the first specimen and 84.5% for the second specimen; the second specimen added 7.3% sensitivity, giving a combined sensitivity of 98.7%. Combined sensitivity declined, and added sensitivity increased, as the time from paralysis onset to stool collection increased (P = 0.032). The sensitivity added by the second specimen is important to detect the last chains of poliovirus transmission and to achieve certification of polio eradication. For sensitive surveillance, two stool specimens should continue to be collected from each AFP patient in India. JF - Epidemiology and Infection AU - Cardemil, C V AU - Rathee, M AU - Gary, H AU - Wannemuehler, K AU - Anand, A AU - Mach, O AU - Bahl, S AU - Wassilak, S AU - Chu, Sy AU - Khera, A AU - Jafari, H S AU - Pallansch, Ma AD - Global Immunization Division, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, USA, ccardemil@cdc.gov PY - 2014 SP - 163 EP - 171 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 142 IS - 1 SN - 0950-2688, 0950-2688 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Sensitivity KW - Poliovirus KW - Data processing KW - Children KW - India KW - Paralysis KW - Epidemiology KW - Reviews KW - Certification KW - Feces KW - H 12000:Epidemiology and Public Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1492632472?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Surveillance+during+an+era+of+rapidly+changing+poliovirus+epidemiology+in+India%3A+the+role+of+one+vs.+two+stool+specimens+in+poliovirus+detection%2C+2000-2010&rft.au=Cardemil%2C+C+V%3BRathee%2C+M%3BGary%2C+H%3BWannemuehler%2C+K%3BAnand%2C+A%3BMach%2C+O%3BBahl%2C+S%3BWassilak%2C+S%3BChu%2C+Sy%3BKhera%2C+A%3BJafari%2C+H+S%3BPallansch%2C+Ma&rft.aulast=Cardemil&rft.aufirst=C&rft.date=2014-01-01&rft.volume=142&rft.issue=1&rft.spage=163&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268813000800 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-12-01 N1 - Number of references - 13 N1 - Last updated - 2016-01-21 N1 - SubjectsTermNotLitGenreText - Paralysis; Data processing; Epidemiology; Children; Feces; Sensitivity; Poliovirus; Reviews; Certification; India DO - http://dx.doi.org/10.1017/S0950268813000800 ER - TY - JOUR T1 - Impact of body mass index on the detection of radiographic localized pleural thickening. AN - 1477552383; 24331259 AB - Subpleural fat can be difficult to distinguish from localized pleural thickening (LPT), a marker of asbestos exposure, on chest radiographs. The aims of this study were to examine the influence of body mass index (BMI) on the performance of radiograph readers when classifying LPT and to model the risk of false test results with varying BMI. Subjects (n = 200) were patients being screened or treated for asbestos-related health outcomes. A film chest radiograph, a digital chest radiograph, and a high-resolution computed tomography (HRCT) chest scan were collected from each subject. All radiographs were independently read by seven B readers and scored using the International Labour Office system. HRCT scans, read by three experienced thoracic radiologists, served as the gold standard for the presence of LPT. We calculated measures of radiograph reader performance, including sensitivity and specificity, for each image modality. We also used logistic regression to estimate the probability of a false-positive and a false-negative result while controlling for covariates. The proportion of false-positive readings correlated with BMI. While controlling for covariates, regression modeling showed the probability of a false-positive result increased with increasing BMI category, younger age, not having pleural calcification, and among subjects not reporting occupational or household contact asbestos exposure. Clinicians should be cautious when evaluating radiographs of younger obese persons for the presence of asbestos-related pleural plaque, particularly in populations having an anticipated low or background prevalence of LPT. Published by Elsevier Inc. JF - Academic radiology AU - Larson, Theodore C AU - Franzblau, Alfred AU - Lewin, Michael AU - Goodman, Alyson B AU - Antao, Vinicius C AD - Division of Toxicology and Human Health Sciences, Agency for Toxic Substances and Disease Registry, 4770 Buford Highway NE, MS F57, Atlanta, GA 30341. Electronic address: TLarson@cdc.gov. ; Department of Environmental Health Sciences, School of Public Health, University of Michigan, Ann Arbor, MI. ; Division of Toxicology and Human Health Sciences, Agency for Toxic Substances and Disease Registry, 4770 Buford Highway NE, MS F57, Atlanta, GA 30341. ; National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA. Y1 - 2014/01// PY - 2014 DA - January 2014 SP - 3 EP - 10 VL - 21 IS - 1 KW - Asbestos KW - 1332-21-4 KW - Index Medicus KW - Radiograph KW - predictive values KW - pneumoconiosis KW - Sensitivity and Specificity KW - Diagnosis, Differential KW - Reproducibility of Results KW - Humans KW - Adult KW - Asbestos -- adverse effects KW - Aged KW - Observer Variation KW - Environmental Exposure -- adverse effects KW - Male KW - Female KW - Radiography, Thoracic KW - Montana KW - False Positive Reactions KW - Pleural Diseases -- etiology KW - Pleura -- diagnostic imaging KW - Body Mass Index KW - Pleural Diseases -- diagnostic imaging KW - Asbestosis -- etiology KW - Adipose Tissue -- diagnostic imaging KW - Asbestosis -- diagnostic imaging UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1477552383?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Academic+radiology&rft.atitle=Impact+of+body+mass+index+on+the+detection+of+radiographic+localized+pleural+thickening.&rft.au=Larson%2C+Theodore+C%3BFranzblau%2C+Alfred%3BLewin%2C+Michael%3BGoodman%2C+Alyson+B%3BAntao%2C+Vinicius+C&rft.aulast=Larson&rft.aufirst=Theodore&rft.date=2014-01-01&rft.volume=21&rft.issue=1&rft.spage=3&rft.isbn=&rft.btitle=&rft.title=Academic+radiology&rft.issn=1878-4046&rft_id=info:doi/10.1016%2Fj.acra.2013.09.014 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2014-08-07 N1 - Date created - 2013-12-16 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Comment In: Acad Radiol. 2014 Jan;21(1):1-2 [24331258] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1016/j.acra.2013.09.014 ER - TY - JOUR T1 - Hospitalizations for Acute Lower Respiratory Tract Infection Due to Respiratory Syncytial Virus in Thailand, 2008-2011 AN - 1622607780; 20900321 AB - Background. Few population-based estimates of the incidence of respiratory syncytial virus (RSV) infection in low- or middle-income countries are available. We describe the incidence and epidemiology of hospitalizations for RSV-associated acute lower respiratory tract infection (ALRI) detected by active population-based surveillance in 2 rural Thailand provinces during 2008-2011. Methods. Patients hospitalized with ALRI were systematically sampled. Consenting patients provided nasopharyngeal swab specimens for RSV testing by real-time reverse-transcription polymerase chain reaction. Results. Of 13 982 enrolled patients hospitalized with ALRI, 1137 (8.1%) were RSV positive. After adjustment for sampling and nonenrollment, the incidence of RSV-associated ALRI hospitalization was 85 cases per 100 000 persons/year. The highest rates occurred among children aged 65 years (130 cases per 100 000 persons/year). Eight (0.7%) RSV-infected study patients died during hospitalization. Annual RSV hospitalizations peaked during July-October with almost no documented RSV hospitalizations during January-June. Conclusions. Our findings demonstrate the substantial contribution of RSV to global ALRI burden, especially in children aged <5 years and the elderly, and underscore the urgent need for effective prevention measures. JF - Journal of Infectious Diseases AU - Naorat, Sathapana AU - Chittaganpitch, Malinee AU - Thamthitiwat, Somsak AU - Henchaichon, Sununta AU - Sawatwong, Pongpun AU - Srisaengchai, Prasong AU - Lu, Ying AU - Chuananon, Somchai AU - Amornintapichet, Tussanee AU - Chantra, Somrak AU - Erdman, Dean D AU - Maloney, Susan A AU - Akarasewi, Passakorn AU - Baggett, Henry C AD - International Emerging Infections Program, Global Disease Detection Regional Center, Thailand Ministry of Public Health (MOPH)-US Centers for Disease Control and Prevention Collaboration, kipb@th.cdc.gov Y1 - 2013/12/15/ PY - 2013 DA - 2013 Dec 15 SP - S238 EP - S245 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 208 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - respiratory syncytial virus KW - acute lower respiratory infection KW - Thailand KW - Elderly KW - Infection KW - Children KW - Respiratory syncytial virus KW - Respiratory tract diseases KW - Prevention KW - Infectious diseases KW - Epidemiology KW - Geriatrics KW - Polymerase chain reaction KW - Young adults KW - Sampling KW - Hospitals KW - Respiratory tract KW - Rural areas KW - H 1000:Occupational Safety and Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1622607780?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Hospitalizations+for+Acute+Lower+Respiratory+Tract+Infection+Due+to+Respiratory+Syncytial+Virus+in+Thailand%2C+2008-2011&rft.au=Naorat%2C+Sathapana%3BChittaganpitch%2C+Malinee%3BThamthitiwat%2C+Somsak%3BHenchaichon%2C+Sununta%3BSawatwong%2C+Pongpun%3BSrisaengchai%2C+Prasong%3BLu%2C+Ying%3BChuananon%2C+Somchai%3BAmornintapichet%2C+Tussanee%3BChantra%2C+Somrak%3BErdman%2C+Dean+D%3BMaloney%2C+Susan+A%3BAkarasewi%2C+Passakorn%3BBaggett%2C+Henry+C&rft.aulast=Naorat&rft.aufirst=Sathapana&rft.date=2013-12-15&rft.volume=208&rft.issue=&rft.spage=S238&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjit456 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-11-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Respiratory tract diseases; Epidemiology; Geriatrics; Polymerase chain reaction; Sampling; Children; Infection; Prevention; Infectious diseases; Elderly; Young adults; Rural areas; Respiratory tract; Hospitals; Respiratory syncytial virus; Thailand DO - http://dx.doi.org/10.1093/infdis/jit456 ER - TY - JOUR T1 - Blood lead level association with lower body weight in NHANES 1999-2006. AN - 1466373463; 24099784 AB - Lead exposure is associated with low birth-weight. The objective of this study is to determine whether lead exposure is associated with lower body weight in children, adolescents and adults. We analyzed data from NHANES 1999-2006 for participants aged ≥3 using multiple logistic and multivariate linear regression. Using age- and sex-standardized BMI Z-scores, overweight and obese children (ages 3-19) were classified by BMI ≥85 th and ≥95 th percentiles, respectively. The adult population (age ≥20) was classified as overweight and obese with BMI measures of 25-29.9 and ≥30, respectively. Blood lead level (BLL) was categorized by weighted quartiles. Multivariate linear regressions revealed a lower BMI Z-score in children and adolescents when the highest lead quartile was compared to the lowest lead quartile (β (SE)=-0.33 (0.07), p<0.001), and a decreased BMI in adults (β (SE)=-2.58 (0.25), p<0.001). Multiple logistic analyses in children and adolescents found a negative association between BLL and the percentage of obese and overweight with BLL in the highest quartile compared to the lowest quartile (OR=0.42, 95% CI: 0.30-0.59; and OR=0.67, 95% CI: 0.52-0.88, respectively). Adults in the highest lead quartile were less likely to be obese (OR=0.42, 95% CI: 0.35-0.50) compared to those in the lowest lead quartile. Further analyses with blood lead as restricted cubic splines, confirmed the dose-relationship between blood lead and body weight outcomes. BLLs are associated with lower body mass index and obesity in children, adolescents and adults. © 2013. JF - Toxicology and applied pharmacology AU - Scinicariello, Franco AU - Buser, Melanie C AU - Mevissen, Meike AU - Portier, Christopher J AD - Division of Toxicology and Human Health Sciences, Agency for Toxic Substances and Disease Registry (ATSDR), Atlanta, GA 30341, USA. Electronic address: fes6@cdc.gov. Y1 - 2013/12/15/ PY - 2013 DA - 2013 Dec 15 SP - 516 EP - 523 VL - 273 IS - 3 KW - Lead KW - 2P299V784P KW - Index Medicus KW - Obesity KW - NHANES KW - Adults KW - Children KW - Body mass index KW - Young Adult KW - Humans KW - Linear Models KW - Child KW - Body Mass Index KW - Obesity -- blood KW - Multivariate Analysis KW - Child, Preschool KW - Environmental Monitoring KW - Cross-Sectional Studies KW - Logistic Models KW - Adult KW - Overweight -- blood KW - Adolescent KW - Female KW - Male KW - Body Weight KW - Nutrition Surveys KW - Lead -- blood UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1466373463?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+applied+pharmacology&rft.atitle=Blood+lead+level+association+with+lower+body+weight+in+NHANES+1999-2006.&rft.au=Scinicariello%2C+Franco%3BBuser%2C+Melanie+C%3BMevissen%2C+Meike%3BPortier%2C+Christopher+J&rft.aulast=Scinicariello&rft.aufirst=Franco&rft.date=2013-12-15&rft.volume=273&rft.issue=3&rft.spage=516&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+applied+pharmacology&rft.issn=1096-0333&rft_id=info:doi/10.1016%2Fj.taap.2013.09.022 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2014-02-10 N1 - Date created - 2013-12-09 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1016/j.taap.2013.09.022 ER - TY - JOUR T1 - Evaluating the safety of influenza vaccine using a claims-based health system AN - 1505340258; 19336227 AB - As part of the Centers for Disease Control and Prevention's monitoring and evaluation activities for influenza vaccines, we examined relationships between influenza vaccination and selected outcomes in the 2009-2010 and 2010-2011 influenza seasons in a claims-based data environment. We included patients with claims for trivalent influenza vaccine (TIV) and/or 2009 pandemic influenza A H1N1 vaccine (H1N1) during the 2009-2010 and 2010-2011 influenza seasons. Patients were followed for several pre-specified outcomes identified in claims. In the 2009-2010 season, no significant increased risks for outcomes following H1N1 vaccination were observed. Following TIV administration, the incidence rate ratios (IRR) for peripheral nervous system disorders and neuropathy was slightly elevated (1.07, 95% CI: 1.01-1.13). The IRR for anaphylaxis following TIV was 28.55 (95% CI: 3.57-228.44). After claims history review, we ultimately found no increased outcome risk following administration of 998,881 TIV and 538,257 H1N1 vaccine doses in the 2009-2010 season, and 1,158,932 TIV doses in the 2010-2011 season. JF - Vaccine AU - McCarthy, Natalie L AU - Gee, Julianne AU - Lin, Nancy D AU - Thyagarajan, Veena AU - Pan, Yi AU - Su, Sue AU - Turnbull, Bruce AU - Chan, K Arnold AU - Weintraub, Eric AD - Centers for Disease Control and Prevention, 1600 Clifton Road, MS-D26, Atlanta, GA 30333, USA, nmccarthy@cdc.gov Y1 - 2013/12/05/ PY - 2013 DA - 2013 Dec 05 SP - 5975 EP - 5982 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 31 IS - 50 SN - 0264-410X, 0264-410X KW - Risk Abstracts; Virology & AIDS Abstracts; Health & Safety Science Abstracts; Immunology Abstracts KW - Vaccine safety KW - Claims KW - Influenza KW - H1N1 KW - Historical account KW - Data processing KW - Anaphylaxis KW - Influenza A KW - peripheral nervous system KW - Safety KW - Disease control KW - Prevention KW - pandemics KW - Reviews KW - Peripheral nervous system KW - Vaccines KW - Neuropathy KW - F 06925:Hypersensitivity KW - R2 23060:Medical and environmental health KW - H 4000:Food and Drugs KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1505340258?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Evaluating+the+safety+of+influenza+vaccine+using+a+claims-based+health+system&rft.au=McCarthy%2C+Natalie+L%3BGee%2C+Julianne%3BLin%2C+Nancy+D%3BThyagarajan%2C+Veena%3BPan%2C+Yi%3BSu%2C+Sue%3BTurnbull%2C+Bruce%3BChan%2C+K+Arnold%3BWeintraub%2C+Eric&rft.aulast=McCarthy&rft.aufirst=Natalie&rft.date=2013-12-05&rft.volume=31&rft.issue=50&rft.spage=5975&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/10.1016%2Fj.vaccine.2013.10.031 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-03-01 N1 - Last updated - 2015-04-16 N1 - SubjectsTermNotLitGenreText - pandemics; Data processing; Anaphylaxis; Influenza A; Disease control; Peripheral nervous system; Vaccines; Neuropathy; Influenza; Historical account; Prevention; Reviews; Safety; peripheral nervous system DO - http://dx.doi.org/10.1016/j.vaccine.2013.10.031 ER - TY - JOUR T1 - Plasmodium-Specific Molecular Assays Produce Uninterpretable Results and Non-Plasmodium spp. Sequences in Field-Collected Anopheles Vectors AN - 1647018057; 21172315 AB - The Malaria Research and Reference Reagent Resource-recommended PLF/UNR/VIR polymerase chain reaction (PCR) was used to detect Plasmodium vivax in Anopheles spp. mosquitoes collected in South Korea. Samples that were amplified were sequenced and compared with known Plasmodium spp. by using the PlasmoDB.org Basic Local Alignment Search Tool/n and the National Center for Biotechnology Information Basic Local Alignment Search Tool/n tools. Results show that the primers PLF/UNR/VIR used in this PCR can produce uninterpretable results and non-specific sequences in field-collected mosquitoes. Three additional PCRs (PLU/VIV, specific for 18S small subunit ribosomal DNA; Pvr47, specific for a nuclear repeat; and GDCW/PLAS, specific for the mitochondrial marker, cytB) were then used to find a more accurate and interpretable assay. Samples that were amplified were again sequenced. The PLU/VIV and Pvr47 assays showed cross-reactivity with non-Plasmodium spp. and an arthropod fungus (Zoophthora lanceolata). The GDCW/PLAS assay amplified only Plasmodium spp. but also amplified the non-human specific parasite P. berghei from an Anopheles belenrae mosquito. Detection of P. berghei in South Korea is a new finding. JF - American Journal of Tropical Medicine and Hygiene AU - Harrison, Genelle F AU - Foley, Desmond H AU - Rueda, Leopoldo M AU - Melanson, Vanessa R AU - Wilkerson, Richard C AU - Long, Lewis S AU - Richardson, Jason H AU - Klein, Terry A AU - Kim, Heung-Chul AU - Lee, Won-Ja AD - Public Health Command Region-Pacific, Camp Zama, Japan; Fifth Medical Detachment, 168th Multifunctional Medical Support Battalion, 65th Medical Brigade, Seoul, South Korea; Division of Malaria and Parasitic Diseases, Korea Center for Disease Control and Prevention, Cheongwon-gun, South Korea; Entomology Branch, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910, Genelle.harrison@mail.mcgill.ca Y1 - 2013/12// PY - 2013 DA - December 2013 SP - 1117 EP - 1121 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 89 IS - 6 SN - 0002-9637, 0002-9637 KW - Entomology Abstracts; Microbiology Abstracts B: Bacteriology; Microbiology Abstracts C: Algology, Mycology & Protozoology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Parasites KW - Cross-reactivity KW - Anopheles KW - Nucleotide sequence KW - Mitochondria KW - Vectors KW - Plasmodium vivax KW - Malaria KW - Hosts KW - Public health KW - Arthropoda KW - DNA KW - Polymerase chain reaction KW - Primers KW - Korea, Rep. KW - Hygiene KW - Aquatic insects KW - Biotechnology KW - J 02410:Animal Diseases KW - Q1 08484:Species interactions: parasites and diseases KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - Q5 08502:Methods and instruments KW - K 03310:Genetics & Taxonomy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1647018057?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Plasmodium-Specific+Molecular+Assays+Produce+Uninterpretable+Results+and+Non-Plasmodium+spp.+Sequences+in+Field-Collected+Anopheles+Vectors&rft.au=Harrison%2C+Genelle+F%3BFoley%2C+Desmond+H%3BRueda%2C+Leopoldo+M%3BMelanson%2C+Vanessa+R%3BWilkerson%2C+Richard+C%3BLong%2C+Lewis+S%3BRichardson%2C+Jason+H%3BKlein%2C+Terry+A%3BKim%2C+Heung-Chul%3BLee%2C+Won-Ja&rft.aulast=Harrison&rft.aufirst=Genelle&rft.date=2013-12-01&rft.volume=89&rft.issue=6&rft.spage=1117&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.12-0581 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2016-02-04 N1 - SubjectsTermNotLitGenreText - Parasites; Nucleotide sequence; DNA; Polymerase chain reaction; Hosts; Hygiene; Aquatic insects; Biotechnology; Public health; Cross-reactivity; Vectors; Mitochondria; Malaria; Primers; Arthropoda; Anopheles; Plasmodium vivax; Korea, Rep. DO - http://dx.doi.org/10.4269/ajtmh.12-0581 ER - TY - JOUR T1 - Nanoscale reference materials for environmental, health and safety measurements: needs, gaps and opportunities AN - 1560130925; 20247220 AB - The authors critically reviewed published lists of nano-objects and their physico-chemical properties deemed important for risk assessment and discussed metrological challenges associated with the development of nanoscale reference materials (RMs). Five lists were identified that contained 25 (classes of) nano-objects; only four (gold, silicon dioxide, silver, titanium dioxide) appeared on all lists. Twenty-three properties were identified for characterisation; only (specific) surface area appeared on all lists. The key themes that emerged from this review were: 1) various groups have prioritised nano-objects for development as "candidate RMs" with limited consensus; 2) a lack of harmonised terminology hinders accurate description of many nano-object properties; 3) many properties identified for characterisation are ill-defined or qualitative and hence are not metrologically traceable; 4) standardised protocols are critically needed for characterisation of nano-objects as delivered in relevant media and as administered to toxicological models; 5) the measurement processes being used to characterise a nano-object must be understood because instruments may measure a given sample in a different way; 6) appropriate RMs should be used for both accurate instrument calibration and for more general testing purposes (e.g., protocol validation); 7) there is a need to clarify that where RMs are not available, if "(representative) test materials" that lack reference or certified values may be useful for toxicology testing and 8) there is a need for consensus building within the nanotechnology and environmental, health and safety communities to prioritise RM needs and better define the required properties and (physical or chemical) forms of the candidate materials. JF - Nanotoxicology AU - Stefaniak, Aleksandr B AU - Hackley, Vincent A AU - Roebben, Gert AU - Ehara, Kensei AU - Hankin, Steve AU - Postek, Michael T AU - Lynch, Iseult AU - Fu, Wei-En AU - Linsinger, Thomas PJ AU - Thunemann, Andreas F AD - National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505, USA, AStefaniak@cdc.gov Y1 - 2013/12// PY - 2013 DA - Dec 2013 SP - 1325 EP - 1337 PB - Informa Healthcare, 52 Vanderbilt Ave. New York New York 10017 USA VL - 7 IS - 8 SN - 1743-5390, 1743-5390 KW - Risk Abstracts; Health & Safety Science Abstracts; Toxicology Abstracts KW - engineered nanomaterials KW - nano-objects KW - nanoparticles KW - nanotechnology KW - reference materials KW - characterisation KW - physico-chemical properties KW - exposure KW - risk KW - Risk assessment KW - Silicon KW - Surface area KW - Safety KW - Physicochemical properties KW - Environmental health KW - Nanotechnology KW - Models KW - Titanium dioxide KW - Reviews KW - Gold KW - Silver KW - Toxicology KW - Silicon dioxide KW - R2 23060:Medical and environmental health KW - H 12000:Epidemiology and Public Health KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1560130925?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Nanotoxicology&rft.atitle=Nanoscale+reference+materials+for+environmental%2C+health+and+safety+measurements%3A+needs%2C+gaps+and+opportunities&rft.au=Stefaniak%2C+Aleksandr+B%3BHackley%2C+Vincent+A%3BRoebben%2C+Gert%3BEhara%2C+Kensei%3BHankin%2C+Steve%3BPostek%2C+Michael+T%3BLynch%2C+Iseult%3BFu%2C+Wei-En%3BLinsinger%2C+Thomas+PJ%3BThunemann%2C+Andreas+F&rft.aulast=Stefaniak&rft.aufirst=Aleksandr&rft.date=2013-12-01&rft.volume=7&rft.issue=8&rft.spage=1325&rft.isbn=&rft.btitle=&rft.title=Nanotoxicology&rft.issn=17435390&rft_id=info:doi/10.3109%2F17435390.2012.739664 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Last updated - 2015-04-09 N1 - SubjectsTermNotLitGenreText - Risk assessment; Titanium dioxide; Reviews; Surface area; Physicochemical properties; Gold; Silver; Silicon dioxide; nanotechnology; Models; Silicon; Safety; Environmental health; Toxicology; Nanotechnology DO - http://dx.doi.org/10.3109/17435390.2012.739664 ER - TY - JOUR T1 - Experimental Infection of Eurasian Collared-Dove (Streptopelia decaocto) with West Nile virus AN - 1492612783; 18870770 AB - The Eurasian collared-dove (Streptopelia decaocto) has recently experienced a population explosion in North America. It is frequently infected with West Nile virus (WNV). To test the hypothesis that the Eurasian collared-dove is competent to transmit WNV, we experimentally infected two cohorts of doves with two different strains of WNV, CO08, and NY99, respectively. Both virus strains induced a low-level viremia, capable of infecting a small fraction of vector mosquitoes. We suggest that the Eurasian collared-dove plays a relatively insignificant role as an amplifying host for WNV, but it may be important where it is locally abundant. JF - Journal of Vector Ecology AU - Panella, Nicholas A AU - Young, Ginger AU - Komar, Nicholas AD - Centers for Disease Control and Prevention, Division of Vector Borne Diseases, Arbovirus Diseases Branch, Fort Collins, CO 80521, U.S.A., nap4@cdc.gov Y1 - 2013/12// PY - 2013 DA - December 2013 SP - 210 EP - 214 PB - Society for Vector Ecology VL - 38 IS - 2 SN - 1081-1710, 1081-1710 KW - ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Virology & AIDS Abstracts; Ecology Abstracts KW - Eurasian collared-dove KW - West Nile virus KW - amplification host KW - virus titer KW - reservoir competence index KW - North America KW - Experimental infection KW - Streptopelia decaocto KW - Vectors KW - Hosts KW - Strains KW - Explosions KW - Disease transmission KW - Public health KW - Viremia KW - Aquatic insects KW - V 22410:Animal Diseases KW - D 04040:Ecosystem and Ecology Studies KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1492612783?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Vector+Ecology&rft.atitle=Experimental+Infection+of+Eurasian+Collared-Dove+%28Streptopelia+decaocto%29+with+West+Nile+virus&rft.au=Panella%2C+Nicholas+A%3BYoung%2C+Ginger%3BKomar%2C+Nicholas&rft.aulast=Panella&rft.aufirst=Nicholas&rft.date=2013-12-01&rft.volume=38&rft.issue=2&rft.spage=210&rft.isbn=&rft.btitle=&rft.title=Journal+of+Vector+Ecology&rft.issn=10811710&rft_id=info:doi/10.1111%2Fj.1948-7134.2013.12032.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-12-01 N1 - Number of references - 26 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Hosts; Strains; Aquatic insects; Explosions; Public health; Disease transmission; Experimental infection; Vectors; Viremia; Streptopelia decaocto; West Nile virus; North America DO - http://dx.doi.org/10.1111/j.1948-7134.2013.12032.x ER - TY - JOUR T1 - Cough and cold medication adverse events after market withdrawal and labeling revision. AN - 1464894228; 24218462 AB - In October 2007, manufacturers voluntarily withdrew over-the-counter (OTC) infant cough and cold medications (CCMs) from the US market. A year later, manufacturers announced OTC CCM labeling would be revised to warn against OTC CCM use by children aged <4 years. We determined whether emergency department (ED) visits for CCM adverse drug events (ADEs) declined after these interventions. We used National Electronic Injury Surveillance System-Cooperative Adverse Drug Event Surveillance data from 2004 to 2011 to estimate the number of ED visits for CCM ADEs before and after each intervention. Among children aged <2 years, ED visits for CCM ADEs decreased from 4.1% of all ADE ED visits before the market withdrawal to 2.4% of all ADE visits afterward (difference in proportion: -1.7%, 95% confidence interval [CI]: -2.7% to -0.6%). Among children aged 2 to 3 years, ED visits for CCM ADEs decreased from 9.5% of all ADE ED visits before the labeling revision announcement to 6.5% of all ADE visits afterward (difference in proportion: -3.0%, 95% CI: -5.4% to -0.6%). Unsupervised ingestions accounted for 64.3% (95% CI: 51.1% to 77.5%) of CCM ADE ED visits involving children aged <2 years after the withdrawal and 88.8% (95% CI: 83.8% to 93.8%) of visits involving children aged 2 to 3 years after the labeling revision announcement. After a voluntary market withdrawal and labeling revision, ED visits for CCM ADEs declined among children aged <2 years and 2 to 3 years relative to ADE ED visits for all drugs. Interventions addressing unsupervised ingestions are needed to reduce CCM ADEs. JF - Pediatrics AU - Hampton, Lee M AU - Nguyen, Duc B AU - Edwards, Jonathan R AU - Budnitz, Daniel S AD - MSc, Centers for Disease Control and Prevention, 1600 Clifton Rd, MS A-24, Atlanta, GA 30329. lhampton@cdc.gov. Y1 - 2013/12// PY - 2013 DA - December 2013 SP - 1047 EP - 1054 VL - 132 IS - 6 KW - Antitussive Agents KW - 0 KW - Expectorants KW - Nasal Decongestants KW - Nonprescription Drugs KW - Abridged Index Medicus KW - Index Medicus KW - medication errors KW - adverse events KW - drug packaging KW - poisoning KW - nonprescription drugs KW - nasal decongestants KW - expectorants KW - antitussive agents KW - product withdrawals KW - drug safety KW - Infant KW - Adverse Drug Reaction Reporting Systems KW - Humans KW - Infant, Newborn KW - Emergency Service, Hospital -- statistics & numerical data KW - Child KW - United States -- epidemiology KW - Male KW - Female KW - Child, Preschool KW - Safety-Based Drug Withdrawals KW - Nonprescription Drugs -- adverse effects KW - Drug-Related Side Effects and Adverse Reactions -- etiology KW - Drug-Related Side Effects and Adverse Reactions -- epidemiology KW - Drug-Related Side Effects and Adverse Reactions -- prevention & control KW - Expectorants -- adverse effects KW - Antitussive Agents -- adverse effects KW - Nasal Decongestants -- adverse effects KW - Drug Labeling UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1464894228?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Pediatrics&rft.atitle=Cough+and+cold+medication+adverse+events+after+market+withdrawal+and+labeling+revision.&rft.au=Hampton%2C+Lee+M%3BNguyen%2C+Duc+B%3BEdwards%2C+Jonathan+R%3BBudnitz%2C+Daniel+S&rft.aulast=Hampton&rft.aufirst=Lee&rft.date=2013-12-01&rft.volume=132&rft.issue=6&rft.spage=1047&rft.isbn=&rft.btitle=&rft.title=Pediatrics&rft.issn=1098-4275&rft_id=info:doi/10.1542%2Fpeds.2013-2236 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2014-01-28 N1 - Date created - 2013-12-03 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Pharmacoepidemiol Drug Saf. 2010 Aug;19(8):819-24 [20533537] N Engl J Med. 2007 Dec 6;357(23):2321-4 [18057333] Med Care. 2007 Oct;45(10 Supl 2):S96-102 [17909391] MMWR Morb Mortal Wkly Rep. 2007 Jan 12;56(1):1-4 [17218934] JAMA. 2006 Oct 18;296(15):1858-66 [17047216] J Clin Pharm Ther. 2002 Aug;27(4):299-309 [12174032] Pediatrics. 2010 Dec;126(6):1100-7 [21098150] Clin Infect Dis. 2011 Jan 1;52 Suppl 1:S83-9 [21342905] Public Health Rep. 2011 May-Jun;126(3):312-7 [21553658] Chest. 2011 Aug;140(2):295-300 [21813527] J Pediatr. 2012 Feb;160(2):190-2 [22056349] J Pediatr. 2013 Nov;163(5):1372-6 [23769500] J Pediatr. 2013 Oct;163(4):1134-9.e1 [23896185] Pediatrics. 2001 Sep;108(3):E52 [11533370] Pediatr Emerg Care. 2013 May;29(5):635-40 [23603655] Pediatr Emerg Care. 2012 Sep;28(9):883-5 [22929136] Pediatr Emerg Care. 2012 Jun;28(6):510-3 [22653460] Clin Pediatr (Phila). 2013 Jun;52(6):534-9 [23539689] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1542/peds.2013-2236 ER - TY - JOUR T1 - Evaluation of the hypersensitivity potential of alternative butter flavorings. AN - 1462187110; 24007741 AB - Concern has been raised over the association of diacetyl with lung disease clinically resembling bronchiolitis obliterans in food manufacturing workers. This has resulted in the need for identification of alternative chemicals to be used in the manufacturing process. Structurally similar chemicals, 2,3-pentanedione, 2,3-hexanedione, 3,4-hexanedione and 2,3-heptanedione, used as constituents of synthetic flavoring agents have been suggested as potential alternatives for diacetyl, however, immunotoxicity data on these chemicals are limited. The present study evaluated the dermal irritation and sensitization potential of diacetyl alternatives using a murine model. None of the chemicals were identified as dermal irritants when tested at concentrations up to 50%. Similar to diacetyl (EC3=17.9%), concentration-dependent increases in lymphocyte proliferation were observed following exposure to all four chemicals, with calculated EC3 values of 15.4% (2,3-pentanedione), 18.2% (2,3-hexanedione), 15.5% (3,4-hexanedione) and 14.1% (2,3-heptanedione). No biologically significant elevations in local or total serum IgE were identified after exposure to 25-50% concentrations of these chemicals. These results demonstrate the potential for development of hypersensitivity responses to these proposed alternative butter flavorings and raise concern about the use of structurally similar replacement chemicals. Additionally, a contaminant with strong sensitization potential was found in varying concentrations in diacetyl obtained from different producers. Published by Elsevier Ltd. JF - Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association AU - Anderson, Stacey E AU - Franko, Jennifer AU - Wells, J R AU - Lukomska, Ewa AU - Meade, B Jean AD - Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, United States. Electronic address: sanderson4@cdc.gov. Y1 - 2013/12// PY - 2013 DA - December 2013 SP - 373 EP - 381 VL - 62 KW - Flavoring Agents KW - 0 KW - Hexanones KW - Irritants KW - Pentanones KW - Immunoglobulin E KW - 37341-29-0 KW - 2,3-hexanedione KW - 559ANR3NVS KW - Butter KW - 8029-34-3 KW - Diacetyl KW - K324J5K4HM KW - 2,3-pentanedione KW - K4WBE45SCM KW - Index Medicus KW - Hypersensitivity KW - LLNA KW - Butter flavorings KW - Occupational Exposure KW - Animals KW - Immunoglobulin E -- blood KW - Diacetyl -- toxicity KW - Lymph Nodes -- pathology KW - Diacetyl -- immunology KW - Mice, Inbred BALB C KW - Pentanones -- toxicity KW - Dose-Response Relationship, Immunologic KW - Hexanones -- toxicity KW - Irritants -- toxicity KW - Hexanones -- immunology KW - Irritants -- immunology KW - Lymphocytes -- drug effects KW - Female KW - Flavoring Agents -- toxicity KW - Dermatitis, Allergic Contact -- etiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1462187110?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Food+and+chemical+toxicology+%3A+an+international+journal+published+for+the+British+Industrial+Biological+Research+Association&rft.atitle=Evaluation+of+the+hypersensitivity+potential+of+alternative+butter+flavorings.&rft.au=Anderson%2C+Stacey+E%3BFranko%2C+Jennifer%3BWells%2C+J+R%3BLukomska%2C+Ewa%3BMeade%2C+B+Jean&rft.aulast=Anderson&rft.aufirst=Stacey&rft.date=2013-12-01&rft.volume=62&rft.issue=&rft.spage=373&rft.isbn=&rft.btitle=&rft.title=Food+and+chemical+toxicology+%3A+an+international+journal+published+for+the+British+Industrial+Biological+Research+Association&rft.issn=1873-6351&rft_id=info:doi/10.1016%2Fj.fct.2013.08.053 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2016-05-06 N1 - Date created - 2013-11-26 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Am J Respir Crit Care Med. 2007 Sep 1;176(5):498-504 [17541015] Basic Clin Pharmacol Toxicol. 2008 Jan;102(1):25-9 [17973901] Curr Opin Pulm Med. 2008 Mar;14(2):141-6 [18303424] Toxicol Sci. 2008 May;103(1):169-80 [18227102] Toxicol Pathol. 2008 Feb;36(2):330-44 [18474946] Int J Occup Med Environ Health. 2008;21(2):173-7 [18715841] J Occup Environ Hyg. 2008 Nov;5(11):679-88 [18720288] Toxicol Sci. 2009 Mar;108(1):173-83 [18940962] J Occup Environ Hyg. 2010 Apr;7(4):185-93 [20094938] Toxicol Sci. 2010 Jun;115(2):435-43 [20176622] Toxicol Sci. 2010 Jun;115(2):453-61 [20200221] Chem Res Toxicol. 2009 Mar 16;22(3):592-603 [19206519] J Occup Environ Hyg. 2011 Feb;8(2):93-103 [21253982] Occup Health Saf. 2011 Mar;80(3):32, 34-6 [21428168] PLoS One. 2011;6(3):e17644 [21464978] Toxicol Sci. 2011 Sep;123(1):231-46 [21705714] J Occup Environ Hyg. 2012;9(2):D33-4 [22233226] Toxicol Pathol. 2012 Apr;40(3):448-65 [22215510] Am J Pathol. 2012 Sep;181(3):829-44 [22894831] Toxicology. 2000 May 5;146(2-3):221-7 [10814854] Allergy. 1999 Oct;54(10):1121-2 [10536899] Chem Res Toxicol. 2013 May 20;26(5):631-3 [23593960] N Engl J Med. 2002 Aug 1;347(5):330-8 [12151470] Toxicol Appl Pharmacol. 2002 Dec 1;185(2):128-35 [12490137] Contact Dermatitis. 2002 Oct;47(4):219-26 [12492521] Toxicol Sci. 2003 Sep;75(1):89-98 [12832659] Eur Respir J. 2004 Aug;24(2):298-302 [15332401] Toxicol Sci. 1999 Apr;48(2):206-17 [10353312] Contact Dermatitis. 1999 Jul;41(1):14-7 [10416702] J Appl Toxicol. 1999 Jul-Aug;19(4):261-6 [10439340] J Occup Environ Hyg. 2005 Mar;2(3):169-78 [15764540] J Occup Environ Med. 2006 Feb;48(2):149-57 [16474263] Chem Res Toxicol. 2006 Sep;19(9):1228-33 [16978028] J Occup Environ Hyg. 2006 Oct;3(10):530-5 [16998985] J Chromatogr A. 2007 Mar 23;1145(1-2):241-5 [17306280] Curr Opin Allergy Clin Immunol. 2007 Apr;7(2):162-7 [17351470] Toxicol Sci. 2007 Jun;97(2):355-63 [17347135] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1016/j.fct.2013.08.053 ER - TY - CPAPER T1 - Prevention Works: A public health approach to preventing violence that affects youth T2 - 141st American Public Health Association Annual Meeting and Exposition AN - 1433511267; 6233211 JF - 141st American Public Health Association Annual Meeting and Exposition AU - Spivak, Howard Y1 - 2013/11/02/ PY - 2013 DA - 2013 Nov 02 KW - Prevention KW - Aggression KW - Violence KW - Public health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1433511267?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.atitle=Prevention+Works%3A+A+public+health+approach+to+preventing+violence+that+affects+youth&rft.au=Spivak%2C+Howard&rft.aulast=Spivak&rft.aufirst=Howard&rft.date=2013-11-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/141am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-31 N1 - Last updated - 2013-09-19 ER - TY - CPAPER T1 - School violence and bullying among sexual minority high school students T2 - 141st American Public Health Association Annual Meeting and Exposition AN - 1433510811; 6233155 JF - 141st American Public Health Association Annual Meeting and Exposition AU - Olsen, Emily AU - Kann, Laura AU - Vivolo-Kantor, Alana AU - Kinchen, Steve Y1 - 2013/11/02/ PY - 2013 DA - 2013 Nov 02 KW - Schools KW - Aggression KW - Violence KW - Bullying KW - Adolescents UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1433510811?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.atitle=School+violence+and+bullying+among+sexual+minority+high+school+students&rft.au=Olsen%2C+Emily%3BKann%2C+Laura%3BVivolo-Kantor%2C+Alana%3BKinchen%2C+Steve&rft.aulast=Olsen&rft.aufirst=Emily&rft.date=2013-11-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/141am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-31 N1 - Last updated - 2013-09-19 ER - TY - CPAPER T1 - Case study: Community health needs assessment and the patient protection and affordable care act T2 - 141st American Public Health Association Annual Meeting and Exposition AN - 1433510713; 6232232 JF - 141st American Public Health Association Annual Meeting and Exposition AU - Ortmann, Leonard Y1 - 2013/11/02/ PY - 2013 DA - 2013 Nov 02 KW - Case studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1433510713?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.atitle=Case+study%3A+Community+health+needs+assessment+and+the+patient+protection+and+affordable+care+act&rft.au=Ortmann%2C+Leonard&rft.aulast=Ortmann&rft.aufirst=Leonard&rft.date=2013-11-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/141am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-31 N1 - Last updated - 2013-09-19 ER - TY - CPAPER T1 - Improving measures of AI/an mortality and cancer incidence through data linkages T2 - 141st American Public Health Association Annual Meeting and Exposition AN - 1433508488; 6231559 JF - 141st American Public Health Association Annual Meeting and Exposition AU - Jim, Melissa AU - Espey, David AU - Roberts, Diana AU - Haverkamp, Donald AU - Weir, Hannah Y1 - 2013/11/02/ PY - 2013 DA - 2013 Nov 02 KW - Mortality KW - Data processing KW - Cancer UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1433508488?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.atitle=Improving+measures+of+AI%2Fan+mortality+and+cancer+incidence+through+data+linkages&rft.au=Jim%2C+Melissa%3BEspey%2C+David%3BRoberts%2C+Diana%3BHaverkamp%2C+Donald%3BWeir%2C+Hannah&rft.aulast=Jim&rft.aufirst=Melissa&rft.date=2013-11-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/141am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-31 N1 - Last updated - 2013-09-19 ER - TY - JOUR T1 - Tuberculosis among the homeless, United States, 1994-2010 AN - 1492633402; 18868157 AB - OBJECTIVES: 1) To describe homeless persons diagnosed with tuberculosis (TB) during the period 1994-2010, and 2) to estimate a TB incidence rate among homeless persons in the United States. METHODS: TB cases reported to the National Tuberculosis Surveillance System were analyzed by origin of birth. Incidence rates were calculated using the US Department of Housing and Urban Development homeless population estimates. Analysis of genotyping results identified clustering as a marker for transmission among homeless TB patients. RESULTS: Of 270948 reported TB cases, 16527 (6%) were homeless. The TB incidence rate among homeless persons ranged from 36 to 47 cases per 100000 population in 2006-2010. Homeless TB patients had over twice the odds of not completing treatment and of belonging to a genotype cluster. US- and foreign-born homeless TB patients had respectively 8 and 12 times the odds of substance abuse. CONCLUSIONS: Compared to the general population, homeless persons had an approximately 10-fold increase in TB incidence, were less likely to complete treatment and more likely to abuse substances. Public health outreach should target homeless populations to reduce the excess burden of TB in this population. JF - International Journal of Tuberculosis and Lung Disease AU - Bamrah, S AU - Woodruff, RSY AU - Powell, K AU - Ghosh, S AU - Kammerer, J S AU - Haddad, M B AD - 1600 Clifton Rd MS E-10, Atlanta, GA 30333, USA, feu3@cdc.gov Y1 - 2013/11// PY - 2013 DA - Nov 2013 SP - 1414 EP - 1419 VL - 17 IS - 11 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology KW - Birth KW - Housing KW - Mycobacterium KW - Genotyping KW - Lung diseases KW - Tuberculosis KW - Genotypes KW - Drug abuse KW - Public health KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1492633402?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Tuberculosis+among+the+homeless%2C+United+States%2C+1994-2010&rft.au=Bamrah%2C+S%3BWoodruff%2C+RSY%3BPowell%2C+K%3BGhosh%2C+S%3BKammerer%2C+J+S%3BHaddad%2C+M+B&rft.aulast=Bamrah&rft.aufirst=S&rft.date=2013-11-01&rft.volume=17&rft.issue=11&rft.spage=1414&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-12-01 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - Birth; Housing; Genotyping; Lung diseases; Tuberculosis; Genotypes; Drug abuse; Public health; Mycobacterium ER - TY - JOUR T1 - Antimicrobial therapies for Q fever AN - 1492608983; 18871456 AB - Q fever is caused by the bacterium Coxiella burnetii and has both acute and chronic forms. The acute disease is a febrile illness often with headache and myalgia that can be self-limiting, whereas the chronic disease typically presents as endocarditis and can be life threatening. The normal therapy for the acute disease is a 2 week course of doxycycline, whereas chronic disease requires 18-24 months of doxycycline in combination with hydroxychloroquine. Alternative treatments are used for pregnant women, young children and those who cannot tolerate doxycycline. Doxycycline resistance is rare, but has been reported. Co-trimoxazole is a currently recommended alternative treatment, but quinolones, rifampin and newer macrolides may also provide some benefit. JF - Expert Review of Anti-infective Therapy AU - Kersh, Gilbert J AD - Centers for Disease Control and Prevention, Mailstop G13, 1600 Clifton Rd. Atlanta, GA 30333, USA +1 404 639 1028 +1 404 718 2116, gkersh@cdc.gov Y1 - 2013/11// PY - 2013 DA - Nov 2013 SP - 1207 EP - 1214 PB - Future Science Group (FSG), Unitec House, 2 Albert Place London N3 1QB United Kingdom VL - 11 IS - 11 SN - 1478-7210, 1478-7210 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology KW - Quinolones KW - Children KW - Co-trimoxazole KW - Pregnancy KW - Endocarditis KW - Antimicrobial agents KW - Coxiella burnetii KW - Rifampin KW - Hydroxychloroquine KW - Reviews KW - Headache KW - Myalgia KW - Q fever KW - Doxycycline KW - A 01340:Antibiotics & Antimicrobials KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1492608983?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Expert+Review+of+Anti-infective+Therapy&rft.atitle=Antimicrobial+therapies+for+Q+fever&rft.au=Kersh%2C+Gilbert+J&rft.aulast=Kersh&rft.aufirst=Gilbert&rft.date=2013-11-01&rft.volume=11&rft.issue=11&rft.spage=1207&rft.isbn=&rft.btitle=&rft.title=Expert+Review+of+Anti-infective+Therapy&rft.issn=14787210&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-01-01 N1 - Number of references - 65 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - Quinolones; Co-trimoxazole; Children; Antimicrobial agents; Endocarditis; Pregnancy; Rifampin; Reviews; Hydroxychloroquine; Headache; Q fever; Myalgia; Doxycycline; Coxiella burnetii ER - TY - JOUR T1 - U.S. PUBLIC HEALTH RESPONSE TO THE FUKUSHIMA RADIOLOGICAL EMERGENCY: ONE AGENCY'S PERSPECTIVE AN - 1468361561; 18770618 AB - On 11 March 2011, northern Japan suffered first a magnitude 9.0 earthquake centered similar to 208 km off the eastern coast and then an ensuing tsunami. These natural events caused widespread destruction along the east coast of Japan. One location hit was the Fukushima Dai-ichi Nuclear Reactor Complex. The destruction at this site initiated a cascade of events that led to multiple reactors overheating, core meltdown, and radionu-clide releases causing widespread radioactive contamination of residential areas, agricultural land, and coastal waters. The public health and medical community in Japan faced many challenges as a result of these multiple events. Our sympathies go out to the Japanese people who will be dealing with the consequences of this incident for years to come. As the radionuclide releases from the Fukushima Dai-ichi Nuclear Reactor escaped into the atmosphere and the ocean, the impact of this disaster was felt around the world. Like many other nations, the U.S. public health system was concerned about the safety of both its citizens living in Japan and citizens residing in the United States as the radioactive materials released from Fukushima were detected in trace amounts as they traveled around the globe. As with any crisis, these events present opportunities to learn and prepare for similar incidents in the future. Events in both Japan and the United States during the response illustrated some U.S. preparedness gaps that had been anticipated previously and others that were newly identified. The Secretary of Health and Human Services has forwarded a report to the National Security Staff discussing public health preparedness gaps and challenges identified by the Fukushima incident Some of these gaps include the following: times Equipment and personnel resources to monitor potentially exposed people for radioactive contamination are insufficient times There is no public health authority to detain people contaminated with radioactive materials. times Public health and medical expertise and treatment capacities for response to radiation emergencies are limited. times There is an insufficient number of radiation health experts. times Public health communications regarding radiation emergency preparedness, health effects of radiation exposures, resilience, and response actions are inadequate. times National and international exposure standards for radiation measurements (and units) and protective action guides lack uniformity. times Access to radiation emergency monitoring data is limited and procedurally complex. times The policy on stockpiling potassium iodide in the Strategic National Stockpile should be revisited. This event was a major disaster for the people of Japan, but it was also a significant public health emergency for the U.S. public health community. We should capitalize upon this rare opportunity to improve our public health preparedness based on the experience of our Japanese colleagues and our own. JF - Health Physics AU - Miller, C W AU - Whitcomb, RC Jr AU - Buzzell, J AU - McCurley, M C AU - Ansari, A AU - Evans, L AD - Radiation Studies Branch, Division of Environmental Hazards and Health Effects, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway NE, MS:F58, Atlanta, GA 30341-3717, USA, CMiller1@cdc.gov Y1 - 2013/11// PY - 2013 DA - Nov 2013 SP - 465 VL - 105 IS - 5 SN - 0017-9078, 0017-9078 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Oceanic Abstracts; Health & Safety Science Abstracts; Pollution Abstracts KW - Iodides KW - Crises KW - Radiation hazards KW - Public health KW - Radioactive materials KW - International standardization KW - Policies KW - Illustrations KW - Disasters KW - Radioactive pollution KW - Coastal waters KW - Identification KW - Security KW - USA KW - Communications KW - Nuclear reactors KW - Oceans KW - Radioisotopes KW - Residential areas KW - Radioactive contamination KW - Emergencies KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - P 1000:MARINE POLLUTION KW - Q5 08502:Methods and instruments KW - O 4060:Pollution - Environment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1468361561?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+Physics&rft.atitle=U.S.+PUBLIC+HEALTH+RESPONSE+TO+THE+FUKUSHIMA+RADIOLOGICAL+EMERGENCY%3A+ONE+AGENCY%27S+PERSPECTIVE&rft.au=Miller%2C+C+W%3BWhitcomb%2C+RC+Jr%3BBuzzell%2C+J%3BMcCurley%2C+M+C%3BAnsari%2C+A%3BEvans%2C+L&rft.aulast=Miller&rft.aufirst=C&rft.date=2013-11-01&rft.volume=105&rft.issue=5&rft.spage=465&rft.isbn=&rft.btitle=&rft.title=Health+Physics&rft.issn=00179078&rft_id=info:doi/10.1097%2FHP.0b013e31829e5597 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-12-01 N1 - Last updated - 2014-12-11 N1 - SubjectsTermNotLitGenreText - Policies; Illustrations; Radioactive materials; Radioactive contamination; Disasters; Emergencies; Identification; Radiation hazards; Public health; Iodides; Crises; Radioactive pollution; Coastal waters; Security; Nuclear reactors; Communications; Oceans; Residential areas; Radioisotopes; International standardization; USA DO - http://dx.doi.org/10.1097/HP.0b013e31829e5597 ER - TY - JOUR T1 - Oxidative Stress and Dermal Toxicity of Iron Oxide Nanoparticles In Vitro AN - 1468356864; 18847830 AB - A number of commercially available metal/metal oxide nanoparticles (NPs) such as superparamagnetic iron oxide (SPION) are utilized by the medical field for a wide variety of applications. These NPs may able to induce dermal toxicity via their physical nature and reactive surface properties. We hypothesize that SPION may be toxic to skin via the ability of particles to be internalized and thereby initiate oxidative stress, inducing redox-sensitive transcription factors affecting/leading to inflammation. Due to the skin's susceptibility to UV radiation, it is also of importance to address the combined effect of UVB and NPs co-exposure. To test this hypothesis, the effects of dextran-coated SPION of different sizes (15-50 nm) and manufacturers (MicroMod, Rostock-Warnemunde, Germany and KTH-Royal Institute of Technology, Stockholm, Sweden) were evaluated in two cell lines: normal human epidermal keratinocytes (HEK) and murine epidermal cells (JB6 P super(+)). HEK cells exposed to 20 nm (KTH and MicroMod) had a decrease in viability, while the 15 and 50 nm particles were not cytotoxic. HEK cells were also capable of internalizing the KTH particles (15 and 20 nm) but not the MicroMod SPION (20 and 50 nm). IL-8 and IL-6 were also elevated in HEK cells following exposure to SPION. Exposure of JB6 P super(+) cells to all SPIONs evaluated resulted in activation of AP-1. Exposure to SPION alone was not sufficient to induce NF- Kappa B activation; however, co-exposure with UVB resulted in significant NF- Kappa B induction in cells exposed to 15 and 20 nm KTH SPION and 50 nm MicroMod particles. Pre-exposure of JB6 P super(+) cells to UVB followed by NPs induced a significant depletion of glutathione, release of cytokines, and cell damage as assessed by release of lactate dehydrogenase. Altogether, these data indicate that co-exposure to UVB and SPIONs was associated with induction of oxidative stress and release of inflammatory mediators. These results verify the need to thoroughly evaluate the adverse effects of UVB when evaluating dermal toxicity of engineered NPs on skin. JF - Cell Biochemistry and Biophysics AU - Murray, Ashley R AU - Kisin, Elena AU - Inman, Alfred AU - Young, Shih-Houng AU - Muhammed, Mamoun AU - Burks, Terrance AU - Uheida, Abdusalam AU - Tkach, Alexey AU - Waltz, Micah AU - Castranova, Vincent AU - Fadeel, Bengt AU - Kagan, Valerian E AU - Riviere, Jim E AU - Monteiro-Riviere, Nancy AU - Shvedova, Anna A AD - Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health (NIOSH), M/L 2015, 1095 Willowdale Road, Morgantown, WV, 26505, USA, ats1@cdc.gov Y1 - 2013/11// PY - 2013 DA - Nov 2013 SP - 461 EP - 476 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 67 IS - 2 SN - 1085-9195, 1085-9195 KW - Toxicology Abstracts KW - Cytokines KW - Skin KW - X 24390:Radioactive Materials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1468356864?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cell+Biochemistry+and+Biophysics&rft.atitle=Oxidative+Stress+and+Dermal+Toxicity+of+Iron+Oxide+Nanoparticles+In+Vitro&rft.au=Murray%2C+Ashley+R%3BKisin%2C+Elena%3BInman%2C+Alfred%3BYoung%2C+Shih-Houng%3BMuhammed%2C+Mamoun%3BBurks%2C+Terrance%3BUheida%2C+Abdusalam%3BTkach%2C+Alexey%3BWaltz%2C+Micah%3BCastranova%2C+Vincent%3BFadeel%2C+Bengt%3BKagan%2C+Valerian+E%3BRiviere%2C+Jim+E%3BMonteiro-Riviere%2C+Nancy%3BShvedova%2C+Anna+A&rft.aulast=Murray&rft.aufirst=Ashley&rft.date=2013-11-01&rft.volume=67&rft.issue=2&rft.spage=461&rft.isbn=&rft.btitle=&rft.title=Cell+Biochemistry+and+Biophysics&rft.issn=10859195&rft_id=info:doi/10.1007%2Fs12013-012-9367-9 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-12-01 N1 - Number of references - 1 N1 - Last updated - 2014-02-11 N1 - SubjectsTermNotLitGenreText - Skin DO - http://dx.doi.org/10.1007/s12013-012-9367-9 ER - TY - JOUR T1 - Carbon nanotube dosimetry: from workplace exposure assessment to inhalation toxicology. AN - 1490757604; 24144386 AB - Dosimetry for toxicology studies involving carbon nanotubes (CNT) is challenging because of a lack of detailed occupational exposure assessments. Therefore, exposure assessment findings, measuring the mass concentration of elemental carbon from personal breathing zone (PBZ) samples, from 8 U.S.-based multi-walled CNT (MWCNT) manufacturers and users were extrapolated to results of an inhalation study in mice. Upon analysis, an inhalable elemental carbon mass concentration arithmetic mean of 10.6 μg/m3 (geometric mean 4.21 μg/m3) was found among workers exposed to MWCNT. The concentration equates to a deposited dose of approximately 4.07 μg/d in a human, equivalent to 2 ng/d in the mouse. For MWCNT inhalation, mice were exposed for 19 d with daily depositions of 1970 ng (equivalent to 1000 d of a human exposure; cumulative 76 yr), 197 ng (100 d; 7.6 yr), and 19.7 ng (10 d; 0.76 yr) and harvested at 0, 3, 28, and 84 d post-exposure to assess pulmonary toxicity. The high dose showed cytotoxicity and inflammation that persisted through 84 d after exposure. The middle dose had no polymorphonuclear cell influx with transient cytotoxicity. The low dose was associated with a low grade inflammatory response measured by changes in mRNA expression. Increased inflammatory proteins were present in the lavage fluid at the high and middle dose through 28 d post-exposure. Pathology, including epithelial hyperplasia and peribronchiolar inflammation, was only noted at the high dose. These findings showed a limited pulmonary inflammatory potential of MWCNT at levels corresponding to the average inhalable elemental carbon concentrations observed in U.S.-based CNT facilities and estimates suggest considerable years of exposure are necessary for significant pathology to occur at that level. JF - Particle and fibre toxicology AU - Erdely, Aaron AU - Dahm, Matthew AU - Chen, Bean T AU - Zeidler-Erdely, Patti C AU - Fernback, Joseph E AU - Birch, M Eileen AU - Evans, Douglas E AU - Kashon, Michael L AU - Deddens, James A AU - Hulderman, Tracy AU - Bilgesu, Suzan A AU - Battelli, Lori AU - Schwegler-Berry, Diane AU - Leonard, Howard D AU - McKinney, Walter AU - Frazer, David G AU - Antonini, James M AU - Porter, Dale W AU - Castranova, Vincent AU - Schubauer-Berigan, Mary K AD - Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA. efi4@cdc.gov. Y1 - 2013/10/21/ PY - 2013 DA - 2013 Oct 21 SP - 53 VL - 10 IS - 1 KW - Nanotubes, Carbon KW - 0 KW - Index Medicus KW - Animals KW - Inhalation Exposure KW - Humans KW - Microscopy, Electron KW - Mice KW - Occupational Exposure KW - Dose-Response Relationship, Drug UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1490757604?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Particle+and+fibre+toxicology&rft.atitle=Carbon+nanotube+dosimetry%3A+from+workplace+exposure+assessment+to+inhalation+toxicology.&rft.au=Erdely%2C+Aaron%3BDahm%2C+Matthew%3BChen%2C+Bean+T%3BZeidler-Erdely%2C+Patti+C%3BFernback%2C+Joseph+E%3BBirch%2C+M+Eileen%3BEvans%2C+Douglas+E%3BKashon%2C+Michael+L%3BDeddens%2C+James+A%3BHulderman%2C+Tracy%3BBilgesu%2C+Suzan+A%3BBattelli%2C+Lori%3BSchwegler-Berry%2C+Diane%3BLeonard%2C+Howard+D%3BMcKinney%2C+Walter%3BFrazer%2C+David+G%3BAntonini%2C+James+M%3BPorter%2C+Dale+W%3BCastranova%2C+Vincent%3BSchubauer-Berigan%2C+Mary+K&rft.aulast=Erdely&rft.aufirst=Aaron&rft.date=2013-10-21&rft.volume=10&rft.issue=1&rft.spage=53&rft.isbn=&rft.btitle=&rft.title=Particle+and+fibre+toxicology&rft.issn=1743-8977&rft_id=info:doi/10.1186%2F1743-8977-10-53 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2014-09-15 N1 - Date created - 2014-01-16 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Nanotoxicology. 2013 Nov;7(7):1179-94 [22881873] Nanotoxicology. 2014 May;8(3):317-27 [23432020] Part Fibre Toxicol. 2013;10:38 [23927530] Part Fibre Toxicol. 2013;10:33 [23895460] Part Fibre Toxicol. 2013;10:23 [23773277] Nat Protoc. 2008;3(6):1101-8 [18546601] Mol Cell Biochem. 2002 May-Jun;234-235(1-2):177-84 [12162431] J Toxicol Environ Health A. 2004 Jan 9;67(1):87-107 [14668113] J Occup Environ Med. 2004 May;46(5):420-7 [15167388] Ann Occup Hyg. 2004 Jul;48(5):439-53 [15240340] Am Rev Respir Dis. 1992 Aug;146(2):454-6 [1489139] Ann ICRP. 1994;24(1-3):1-482 [7726471] Risk Anal. 1998 Jun;18(3):293-7 [9664725] Environ Toxicol. 2007 Aug;22(4):415-21 [17607736] Toxicol Sci. 2007 Nov;100(1):203-14 [17660506] Inhal Toxicol. 2008 Jun;20(8):741-9 [18569096] Am J Physiol Lung Cell Mol Physiol. 2008 Oct;295(4):L552-65 [18658273] Nano Lett. 2009 Jan;9(1):36-43 [19049393] Nat Nanotechnol. 2009 Jul;4(7):451-6 [19581899] Inhal Toxicol. 2009 Oct;21(12):1053-61 [19555230] Toxicol Sci. 2009 Dec;112(2):468-81 [19584127] Toxicol Sci. 2010 Jan;113(1):226-42 [19822600] J Occup Environ Hyg. 2010 Mar;7(3):163-76 [20063229] Inhal Toxicol. 2010 Apr;22(5):369-81 [20121582] Toxicology. 2010 Mar 10;269(2-3):136-47 [19857541] Nat Nanotechnol. 2010 May;5(5):354-9 [20364135] Toxicol Mech Methods. 2010 Jun;20(5):267-72 [20482408] Ann Occup Hyg. 2010 Jul;54(5):514-31 [20447936] Occup Environ Med. 2011 May;68(5):345-53 [20952555] J Occup Environ Med. 2011 Jun;53(6 Suppl):S62-7 [21654420] J Occup Environ Med. 2011 Jun;53(6 Suppl):S80-6 [21654424] Part Fibre Toxicol. 2011;8:21 [21781304] Ann Occup Hyg. 2011 Nov;55(9):1016-36 [21965464] Mutat Res. 2012 Jun 14;745(1-2):28-37 [22178868] Ann Occup Hyg. 2012 Jul;56(5):542-56 [22156567] J Occup Environ Hyg. 2012;9(9):543-55 [22816668] Inhal Toxicol. 2012 Oct;24(12):798-820 [23033994] Chest. 2012 Aug;142(2):412-8 [21998260] Int J Mol Sci. 2012;13(11):13781-803 [23203034] Part Fibre Toxicol. 2012;9:38 [23072542] Ann Occup Hyg. 2013 Mar;57(2):261-77 [23065675] Ann Occup Hyg. 2013 Apr;57(3):328-44 [23100605] Inhal Toxicol. 2013 Mar;25(4):199-210 [23480196] ACS Nano. 2013 Mar 26;7(3):2352-68 [23414138] Small. 2013 Aug 26;9(16):2721-9, 2720 [23447468] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1186/1743-8977-10-53 ER - TY - JOUR T1 - Water, Sanitation and Hygiene in Haiti: Past, Present, and Future AN - 1647000636; 21172247 AB - Haiti has the lowest rates of access to improved water and sanitation infrastructure in the western hemisphere. This situation was likely exacerbated by the earthquake in 2010 and also contributed to the rapid spread of the cholera epidemic that started later that same year. This report examines the history of the water, sanitation, and hygiene (WASH) sector in Haiti, considering some factors that have influenced WASH conditions in the country. We then discuss the situation sine the earthquake and subsequent cholera epidemic, and the responses to those events. Finally, drawing on Haiti's National Plan of Action for the Elimination of Cholera in Haiti 2013-2022, we suggest some actions that could help bring about long-term WASH improvements for the future. Because the current WASH situation has evolved over decades of limited attention and resources, it will take a long-term, sustained effort to improve the situation. JF - American Journal of Tropical Medicine and Hygiene AU - Gelting, Richard AU - Bliss, Katherine AU - Patrick, Molly AU - Lockhart, Gabriella AU - Handzel, Thomas AD - National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway, Mailstop F-58, Atlanta, GA 30341; Center for Strategic and International Studies, Washington, District of Columbia, rgelting@cdc.gov Y1 - 2013/10// PY - 2013 DA - October 2013 SP - 665 EP - 670 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 89 IS - 4 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Earthquakes KW - Sanitation KW - Epidemics KW - Pathogenic bacteria KW - Bacterial diseases KW - Cholera KW - Hygiene KW - ASW, Caribbean Sea, Greater Antilles, Haiti KW - K 03400:Human Diseases KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08521:Mechanical and natural changes KW - J 02450:Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1647000636?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Water%2C+Sanitation+and+Hygiene+in+Haiti%3A+Past%2C+Present%2C+and+Future&rft.au=Gelting%2C+Richard%3BBliss%2C+Katherine%3BPatrick%2C+Molly%3BLockhart%2C+Gabriella%3BHandzel%2C+Thomas&rft.aulast=Gelting&rft.aufirst=Richard&rft.date=2013-10-01&rft.volume=89&rft.issue=4&rft.spage=665&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.13-0217 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Earthquakes; Epidemics; Pathogenic bacteria; Bacterial diseases; Hygiene; Sanitation; Cholera; ASW, Caribbean Sea, Greater Antilles, Haiti DO - http://dx.doi.org/10.4269/ajtmh.13-0217 ER - TY - JOUR T1 - Seroepidemiology of diphtheria and tetanus among children and young adults in Tajikistan: Nationwide population-based survey, 2010 AN - 1468355189; 18868096 AB - Background: Tajikistan had a major diphtheria outbreak ( similar to 10, 000 cases) in the 1990s, which was controlled after nationwide immunization campaigns with diphtheria-tetanus toxoid in 1995 and 1996. Since 2000, only 52 diphtheria cases have been reported. However, in coverage surveys conducted in 2000 and 2005, diphtheria-tetanus-pertussis vaccine coverage was lower than administratively reported estimates raising concerns about potential immunity gaps. To further assess population immunity to diphtheria in Tajikistan, diphtheria antibody testing was included in a large-scale nationwide serosurvey for vaccine-preventable diseases conducted in connection with a poliomyelitis outbreak in 2010. In addition, the serosurvey provided an opportunity to assess population immunity to tetanus. Methods: Residents of all regions of Tajikistan aged 1-24 years were included in the serosurvey implemented during September-October 2010. Participants were selected through stratified cluster sampling. Specimens were tested for diphtheria antibodies using a Vero cell neutralization assay and for tetanus antibodies using an anti-tetanus IgG ELISA. Antibody concentrations greater than or equal to 0.1 IU/mL were considered seropositive. Results: Overall, 51.4% (95% CI, 47.1%-55.6%) of participants were seropositive for diphtheria and 78.9% (95% CI, 74.7%-82.5%) were seropositive for tetanus. The lowest percentages of seropositivity for both diseases were observed among persons aged 10-19 years: diphtheria seropositivity was 37.1% (95% CI, 31.0%-43.7%) among 10-14 year-olds, and 35.3% (95% CI, 29.9%-41.1%) among 15-19 year-olds; tetanus seropositivity in respective age groups was 65.3% (95% CI, 58.4%-71.6%) and 70.1% (95% CI, 64.5%-75.2%). Conclusions: Population immunity for diphtheria in Tajikistan is low, particularly among 10-19 year-olds. Population immunity to tetanus is generally higher than for diphtheria, but is suboptimal among 10-19 year-olds. These findings highlight the need to improve routine immunization service delivery, and support a one-time supplementary immunization campaign with diphtheria-tetanus toxoid among birth cohorts aged 1-19 years in 2010 (3-21 years in 2012) to close immunity gaps and prevent diphtheria outbreaks. JF - Vaccine AU - Khetsuriani, N AU - Zakikhany, K AU - Jabirov, S AU - Saparova, N AU - Ursu, P AU - Wannemuehler, K AU - Wassilak, S AU - Efstratiou, A AU - Martin, R AD - Team Lead for the European Region, Disease Eradication and Elimination Branch, Global, Immunization Division, Center for Global Health, CDC, 1600 Clifton Rd, MS-A04, Atlanta, GA 30333, United States, nck7@cdc.gov Y1 - 2013/10/01/ PY - 2013 DA - 2013 Oct 01 SP - 4917 EP - 4922 VL - 31 IS - 42 SN - 0264-410X, 0264-410X KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Poliovirus KW - Age KW - Enzyme-linked immunosorbent assay KW - Vero cells KW - Toxoids KW - Immunity KW - Diphtheria KW - Tetanus KW - Children KW - Immunization KW - Poliomyelitis KW - Immunoglobulin G KW - Vaccines KW - Sampling KW - Seroepidemiology KW - F 06905:Vaccines KW - J 02350:Immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1468355189?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Seroepidemiology+of+diphtheria+and+tetanus+among+children+and+young+adults+in+Tajikistan%3A+Nationwide+population-based+survey%2C+2010&rft.au=Khetsuriani%2C+N%3BZakikhany%2C+K%3BJabirov%2C+S%3BSaparova%2C+N%3BUrsu%2C+P%3BWannemuehler%2C+K%3BWassilak%2C+S%3BEfstratiou%2C+A%3BMartin%2C+R&rft.aulast=Khetsuriani&rft.aufirst=N&rft.date=2013-10-01&rft.volume=31&rft.issue=42&rft.spage=4917&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-12-01 N1 - Last updated - 2014-05-02 N1 - SubjectsTermNotLitGenreText - Enzyme-linked immunosorbent assay; Age; Vero cells; Diphtheria; Immunity; Toxoids; Children; Tetanus; Immunization; Poliomyelitis; Immunoglobulin G; Seroepidemiology; Sampling; Vaccines; Poliovirus ER - TY - JOUR T1 - An empirical comparison of low-dose extrapolation from points of departure (PoD) compared to extrapolations based upon methods that account for model uncertainty. AN - 1431298606; 23831127 AB - Experiments with relatively high doses are often used to predict risks at appreciably lower doses. A point of departure (PoD) can be calculated as the dose associated with a specified moderate response level that is often in the range of experimental doses considered. A linear extrapolation to lower doses often follows. An alternative to the PoD method is to develop a model that accounts for the model uncertainty in the dose-response relationship and to use this model to estimate the risk at low doses. Two such approaches that account for model uncertainty are model averaging (MA) and semi-parametric methods. We use these methods, along with the PoD approach in the context of a large animal (40,000+ animal) bioassay that exhibited sub-linearity. When models are fit to high dose data and risks at low doses are predicted, the methods that account for model uncertainty produce dose estimates associated with an excess risk that are closer to the observed risk than the PoD linearization. This comparison provides empirical support to accompany previous simulation studies that suggest methods that incorporate model uncertainty provide viable, and arguably preferred, alternatives to linear extrapolation from a PoD. Published by Elsevier Inc. JF - Regulatory toxicology and pharmacology : RTP AU - Wheeler, Matthew W AU - Bailer, A John AD - Risk Evaluation Branch, National Institute for Occupational Safety and Health, 4626 Columbia Parkway, Cincinnati, OH 45226, USA. Electronic address: mwheeler@cdc.gov. Y1 - 2013/10// PY - 2013 DA - October 2013 SP - 75 EP - 82 VL - 67 IS - 1 KW - Index Medicus KW - Dose–response data KW - Linear extrapolation KW - Model averaging KW - Semi parametric methods KW - Cancer risk estimation KW - Benchmark doses KW - Animals KW - Dose-Response Relationship, Drug KW - Benchmarking KW - Risk Assessment KW - Uncertainty KW - Models, Biological UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1431298606?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Regulatory+toxicology+and+pharmacology+%3A+RTP&rft.atitle=An+empirical+comparison+of+low-dose+extrapolation+from+points+of+departure+%28PoD%29+compared+to+extrapolations+based+upon+methods+that+account+for+model+uncertainty.&rft.au=Wheeler%2C+Matthew+W%3BBailer%2C+A+John&rft.aulast=Wheeler&rft.aufirst=Matthew&rft.date=2013-10-01&rft.volume=67&rft.issue=1&rft.spage=75&rft.isbn=&rft.btitle=&rft.title=Regulatory+toxicology+and+pharmacology+%3A+RTP&rft.issn=1096-0295&rft_id=info:doi/10.1016%2Fj.yrtph.2013.06.006 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2014-05-19 N1 - Date created - 2013-09-09 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: J Environ Pathol Toxicol. 1980;3(3 Spec No):1-7 [7365374] Risk Anal. 2007 Feb;27(1):111-23 [17362404] Risk Anal. 2007 Jun;27(3):659-70 [17640214] Chem Res Toxicol. 2009 Jul;22(7):1264-76 [19449824] Risk Anal. 2012 Jul;32(7):1207-18 [22385024] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1016/j.yrtph.2013.06.006 ER - TY - CPAPER T1 - Responding to a National Outbreak of Fungal Meningitis T2 - 53rd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2013) AN - 1510108573; 6271336 JF - 53rd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2013) AU - Jernigan, John Y1 - 2013/09/10/ PY - 2013 DA - 2013 Sep 10 KW - Outbreaks UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1510108573?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=53rd+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2013%29&rft.atitle=Responding+to+a+National+Outbreak+of+Fungal+Meningitis&rft.au=Jernigan%2C+John&rft.aulast=Jernigan&rft.aufirst=John&rft.date=2013-09-10&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=53rd+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2013%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/start.aspx?mkey={7DD36E88-52C3-4FF1-A5DF-1D00766558B8} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-03-24 N1 - Last updated - 2014-03-26 ER - TY - JOUR T1 - IDSR as a Platform for Implementing IHR in African Countries AN - 1654678380; 21192502 AB - Of the 46 countries in the World Health Organization (WHO) African region (AFRO), 43 are implementing Integrated Disease Surveillance and Response (IDSR) guidelines to improve their abilities to detect, confirm, and respond to high-priority communicable and noncommunicable diseases. IDSR provides a framework for strengthening the surveillance, response, and laboratory core capacities required by the revised International Health Regulations [IHR (2005)]. In turn, IHR obligations can serve as a driving force to sustain national commitments to IDSR strategies. The ability to report potential public health events of international concern according to IHR (2005) relies on early warning systems founded in national surveillance capacities. Public health events reported through IDSR to the WHO Emergency Management System in Africa illustrate the growing capacities in African countries to detect, assess, and report infectious and noninfectious threats to public health. The IHR (2005) provide an opportunity to continue strengthening national IDSR systems so they can characterize outbreaks and respond to public health events in the region. JF - Biosecurity and Bioterrorism AU - Kasolo, Francis AU - Yoti, Zabulon AU - Bakyaita, Nathan AU - Gaturuku, Peter AU - Katz, Rebecca AU - Fischer, Julie E AU - Perry, Helen N AD - Disease Prevention and Control; World Health Organization Regional Office for Africa, Brazzaville, Republic of Congo, hap5@cdc.gov Y1 - 2013/09// PY - 2013 DA - Sep 2013 SP - 163 EP - 169 PB - Mary Ann Liebert, Inc., 2 Madison Ave Larchmont NY 10538-1962 United States VL - 11 IS - 3 SN - 1538-7135, 1538-7135 KW - Health & Safety Science Abstracts KW - Emergency preparedness KW - Guidelines KW - Disasters KW - Africa KW - Outbreaks KW - International regulations KW - Bioterrorism KW - Warning systems KW - Public health KW - H 6000:Natural Disasters/Civil Defense/Emergency Management UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1654678380?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biosecurity+and+Bioterrorism&rft.atitle=IDSR+as+a+Platform+for+Implementing+IHR+in+African+Countries&rft.au=Kasolo%2C+Francis%3BYoti%2C+Zabulon%3BBakyaita%2C+Nathan%3BGaturuku%2C+Peter%3BKatz%2C+Rebecca%3BFischer%2C+Julie+E%3BPerry%2C+Helen+N&rft.aulast=Kasolo&rft.aufirst=Francis&rft.date=2013-09-01&rft.volume=11&rft.issue=3&rft.spage=163&rft.isbn=&rft.btitle=&rft.title=Biosecurity+and+Bioterrorism&rft.issn=15387135&rft_id=info:doi/10.1089%2Fbsp.2013.0032 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-02-01 N1 - Last updated - 2015-02-18 N1 - SubjectsTermNotLitGenreText - Emergency preparedness; Guidelines; Disasters; International regulations; Outbreaks; Bioterrorism; Warning systems; Public health; Africa DO - http://dx.doi.org/10.1089/bsp.2013.0032 ER - TY - JOUR T1 - Avian Hosts of West Nile Virus in Arizona AN - 1647024029; 21172215 AB - West Nile virus (WNV) causes sporadic outbreaks of human encephalitis in Phoenix, Arizona. To identify amplifying hosts of WNV in the Phoenix area, we blood-sampled resident birds and measured antibody prevalence following an outbreak in the East Valley of metropolitan Phoenix during summer, 2010. House sparrow (Passer domesticus), house finch (Haemorhous mexicanus), great-tailed grackle (Quiscalus mexicanus), and mourning dove (Zenaida macroura) accounted for most WNV infections among locally resident birds. These species roost communally after early summer breeding. In September 2010, Culex vector-avian host contact was 3-fold greater at communal bird roosts compared with control sites, as determined by densities of resting mosquitoes with previous vertebrate contact (i.e., blood-engorged or gravid mosquitoes). Because of the low competence of mourning doves, these were considered weak amplifiers but potentially effective free-ranging sentinels. Highly competent sparrows, finches, and grackles were predicted to be key amplifying hosts for WNV in suburban Phoenix. JF - American Journal of Tropical Medicine and Hygiene AU - Komar, Nicholas AU - Panella, Nicholas A AU - Young, Ginger R AU - Brault, Aaron C AU - Levy, Craig E AD - Centers for Disease Control and Prevention (CDC), Arbovirus Diseases Branch, Fort Collins, Colorado; Arizona Department of Health Services, Phoenix, Arizona, NKomar@cdc.gov Y1 - 2013/09// PY - 2013 DA - September 2013 SP - 474 EP - 481 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 89 IS - 3 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Pest control KW - Infection KW - Encephalitis KW - Public health KW - Passer domesticus KW - Culex KW - Antibodies KW - Breeding KW - Interspecific relationships KW - USA, Arizona KW - Zenaida macroura KW - Hygiene KW - Aquatic insects KW - Quiscalus mexicanus KW - West Nile virus KW - USA, Arizona, Phoenix KW - Roosts KW - K 03410:Animal Diseases KW - V 22410:Animal Diseases KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08502:Methods and instruments KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1647024029?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Avian+Hosts+of+West+Nile+Virus+in+Arizona&rft.au=Komar%2C+Nicholas%3BPanella%2C+Nicholas+A%3BYoung%2C+Ginger+R%3BBrault%2C+Aaron+C%3BLevy%2C+Craig+E&rft.aulast=Komar&rft.aufirst=Nicholas&rft.date=2013-09-01&rft.volume=89&rft.issue=3&rft.spage=474&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.13-0061 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Antibodies; Interspecific relationships; Pest control; Hygiene; Aquatic insects; Public health; Breeding; Infection; Encephalitis; Roosts; Passer domesticus; Culex; Zenaida macroura; West Nile virus; Quiscalus mexicanus; USA, Arizona; USA, Arizona, Phoenix DO - http://dx.doi.org/10.4269/ajtmh.13-0061 ER - TY - JOUR T1 - Chronic Obstructive Pulmonary Disease Prevalence Among Nonsmokers by Occupation in the United States AN - 1443374378; 18662442 AB - Objective: To examine the prevalence of chronic obstructive pulmonary disease (COPD) among nonsmokers by occupation in the United States. Methods: The 1997 to 2004 National Health Interview Survey data for working adults aged 25 years or more were used to estimate the COPD prevalence and to examine change in COPD prevalence between 1997 to 2000 and 2001 to 2004 by occupational groups. Results: During 1997 to 2004, COPD prevalence was 2.8%. The COPD prevalence was highest in financial records processing (4.6%) occupations. There was a slight increase in COPD prevalence during the two survey periods from 2.8% during 1997 to 2000 compared with 2.9% during 2001 to 2004. Conclusions: No significant changes in the COPD prevalence between the two periods were found. Nevertheless, the elevated COPD prevalence in certain occupational groups suggests that other risk factors play a role in developing COPD. JF - Journal of Occupational and Environmental Medicine AU - Bang, K M AU - Syamlal, G AU - Mazurek, J M AU - Wassell, J T AD - Division of Respira tory Disease Studies. RM H-G900.2, National Institute for Occupational Safety and Health. CDC, 1095 Willowdale Road. Morgantown, WV 26505, USA, kmb2@cdc.gov PY - 2013 SP - 1021 EP - 1026 VL - 55 IS - 9 SN - 1076-2752, 1076-2752 KW - Risk Abstracts; Health & Safety Science Abstracts KW - USA KW - Risk factors KW - Chronic obstructive pulmonary disease KW - H 1000:Occupational Safety and Health KW - R2 23070:Economics, organization UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1443374378?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Chronic+Obstructive+Pulmonary+Disease+Prevalence+Among+Nonsmokers+by+Occupation+in+the+United+States&rft.au=Bang%2C+K+M%3BSyamlal%2C+G%3BMazurek%2C+J+M%3BWassell%2C+J+T&rft.aulast=Bang&rft.aufirst=K&rft.date=2013-09-01&rft.volume=55&rft.issue=9&rft.spage=1021&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e31829baa97 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-10-01 N1 - Last updated - 2015-12-23 N1 - SubjectsTermNotLitGenreText - Risk factors; Chronic obstructive pulmonary disease; USA DO - http://dx.doi.org/10.1097/JOM.0b013e31829baa97 ER - TY - JOUR T1 - State-Level Estimates of Cancer-Related Absenteeism Costs AN - 1443373954; 18662441 AB - Background: Cancer is one of the top five most costly diseases in the United States and leads to substantial work loss. Nevertheless, limited state-level estimates of cancer absenteeism costs have been published. Methods: In analyses of data from the 2004-2008 Medical Expenditure Panel Survey, the 2004 National Nursing Home Survey, the U.S. Census Bureau for 2008, and the 2009 Current Population Survey, we used regression modeling to estimate annual state-level absenteeism costs attributable to cancer from 2004 to 2008. Results: We estimated that the state-level median number of days of absenteeism per year among employed cancer patients was 6.1 days and that annual state-level cancer absenteeism costs ranged from $14.9 million to $915.9 million (median = $115.9 million) across states in 2010 dollars. Absenteeism costs are approximately 6.5% of the costs of premature cancer mortality. Conclusions: The results from this study suggest that lost productivity attributable to cancer is a substantial cost to employees and employers and contributes to estimates of the overall impact of cancer in a state population. JF - Journal of Occupational and Environmental Medicine AU - Tangka, F K AU - Trogdon, J G AU - Nwaise, I AU - Ekwueme, DU AU - Guy, GP Jr AU - Orenstein, D AD - Centers for Disease Control and Prevention, DCPC/EARB, 4770 Buford Highway NE, MS F-76, Atlanta, GA 30341-3717, USA, ftangka@cdc.gov PY - 2013 SP - 1015 EP - 1020 VL - 55 IS - 9 SN - 1076-2752, 1076-2752 KW - Health & Safety Science Abstracts KW - Mortality KW - USA KW - Economics KW - Census KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1443373954?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=State-Level+Estimates+of+Cancer-Related+Absenteeism+Costs&rft.au=Tangka%2C+F+K%3BTrogdon%2C+J+G%3BNwaise%2C+I%3BEkwueme%2C+DU%3BGuy%2C+GP+Jr%3BOrenstein%2C+D&rft.aulast=Tangka&rft.aufirst=F&rft.date=2013-09-01&rft.volume=55&rft.issue=9&rft.spage=1015&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e3182a2a467 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-10-01 N1 - Last updated - 2015-12-23 N1 - SubjectsTermNotLitGenreText - Mortality; Economics; Census; USA DO - http://dx.doi.org/10.1097/JOM.0b013e3182a2a467 ER - TY - JOUR T1 - Concordance Between Current Job and Usual Job in Occupational and Industry Groupings: Assessment of the 2010 National Health Interview Survey AN - 1443369858; 18662449 AB - Objective: To determine whether current job is a reasonable surrogate for usual job. Methods: Data from the 2010 National Health Interview Survey were utilized to determine concordance between current and usual jobs for workers employed within the past year. Concordance was quantitated by kappa values for both simple and detailed industry and occupational groups. Good agreement is considered to be present when kappa values exceed 60. Results: Overall kappa values plus or minus standard errors were 74.5 plus or minus 0.5 for simple industry, 72.4 plus or minus 0.5 for detailed industry, 76.3 plus or minus 0.4 for simple occupation, 73.7 plus or minus 0.5 for detailed occupation, and 80.4 plus or minus 0.6 for very broad occupational class. Sixty-five of 73 detailed industry groups and 78 of 81 detailed occupation groups evaluated had good agreement between current and usual jobs. Conclusions: Current job can often serve as a reliable surrogate for usual job in epidemiologic studies. JF - Journal of Occupational and Environmental Medicine AU - Luckhaupt, SE AU - Cohen, MA AU - Calvert, G M AD - National Institute for Occupational Safety and Health, 4676 Columbia Parkway, R-17, Cincinnati, OH 45226, USA, pks8@cdc.gov PY - 2013 SP - 1074 EP - 1090 VL - 55 IS - 9 SN - 1076-2752, 1076-2752 KW - Health & Safety Science Abstracts KW - Occupational health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1443369858?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Concordance+Between+Current+Job+and+Usual+Job+in+Occupational+and+Industry+Groupings%3A+Assessment+of+the+2010+National+Health+Interview+Survey&rft.au=Luckhaupt%2C+SE%3BCohen%2C+MA%3BCalvert%2C+G+M&rft.aulast=Luckhaupt&rft.aufirst=SE&rft.date=2013-09-01&rft.volume=55&rft.issue=9&rft.spage=1074&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e318297321d LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-10-01 N1 - Last updated - 2015-12-23 N1 - SubjectsTermNotLitGenreText - Occupational health DO - http://dx.doi.org/10.1097/JOM.0b013e318297321d ER - TY - JOUR T1 - Work-Related Knee Injuries Treated in US Emergency Departments AN - 1443369189; 18662450 AB - Objective: To characterize work-related knee injuries treated in US emergency departments (EDs). Methods: We characterized work-related knee injuries treated in EDs in 2007 and examined trends from 1998 to 2007 by using the National Electronic Injury Surveillance System--occupational supplement. Results: In 2007, 184,300 ( plus or minus 54,000; 95% confidence interval) occupational knee injuries were treated in US EDs, accounting for 5% of the 3.4 ( plus or minus 0.9) million ED-treated occupational injuries. The ED-treated knee injury rate was 13 ( plus or minus 4) injuries per 10,000 full-time equivalent workers. Younger workers and older female workers had high rates. Strains/sprains and contusions/abrasions were common--frequently resulting from falls and bodily reaction/overexertion events. Knee injury rates declined from 1998 through 2007. Conclusions: Knee injury prevention should emphasize reducing falls and bodily reaction/overexertion events, particularly among all youth and older women. JF - Journal of Occupational and Environmental Medicine AU - Chen, Z AU - Chakrabarty, S AU - Levine, R S AU - Aliyu, M H AU - Ding, T AU - Jackson, L L AD - Division of Safety Research, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, 1095 Willowdale Rd, MS 1808, Morgantown, WV 26505, USA, LLJackson@cdc.gov PY - 2013 SP - 1091 EP - 1099 VL - 55 IS - 9 SN - 1076-2752, 1076-2752 KW - Health & Safety Science Abstracts KW - USA KW - Prevention KW - Injuries KW - Occupational safety KW - Emergency medical services KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1443369189?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Work-Related+Knee+Injuries+Treated+in+US+Emergency+Departments&rft.au=Chen%2C+Z%3BChakrabarty%2C+S%3BLevine%2C+R+S%3BAliyu%2C+M+H%3BDing%2C+T%3BJackson%2C+L+L&rft.aulast=Chen&rft.aufirst=Z&rft.date=2013-09-01&rft.volume=55&rft.issue=9&rft.spage=1091&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e31829b27bf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-10-01 N1 - Last updated - 2015-12-23 N1 - SubjectsTermNotLitGenreText - Prevention; Injuries; Occupational safety; Emergency medical services; USA DO - http://dx.doi.org/10.1097/JOM.0b013e31829b27bf ER - TY - JOUR T1 - HIV Testing and Intimate Partner Violence Among Non-Pregnant Women in 15 US States/Territories: Findings from Behavioral Risk Factor Surveillance System Survey Data AN - 1434034331; 18535031 AB - Intimate partner violence (IPV) has been shown to be associated with higher rates of HIV infection among women, underscoring the importance of encouraging IPV victims to receive HIV testing. However, we do not know how much HIV testing behavior is influenced by IPV victimization. The current study characterized the association between individual types of IPV and HIV testing in a large sample of non-pregnant women in 15 US states/territories. The 2005 Behavioral Risk Factor Surveillance System data were analyzed after restricting the sample to non-pregnant women. The dependent variable, whether a woman ever had an HIV test, was examined in relation to individual types of IPV victimization (threatened physical violence; attempted physical violence; completed physical violence; and unwanted sex). Associations between HIV testing and types of IPV were assessed using adjusted risk ratios (aRR) that controlled for demographics and HIV-related risk factors (intravenous drug use, sexually transmitted diseases, exchange sex, unprotected anal sex). Approximately 28.6 % of women reported ever having experienced IPV, and 52.8 % of these women reported being tested for HIV. Among women who had not experienced IPV, 32.9 % reported ever having been tested for HIV. HIV testing was associated with lifetime experience of threatened violence (aRR = 1.43; 95 % CI = 1.24-1.65), attempted violence (aRR = 1.43; 95 % CI = 1.20-1.69), completed physical violence (aRR = 1.30; 95 % CI = 1.13-1.48), and unwanted sex (aRR = 1.66; 95 % CI = 1.48-1.86). Women who experienced each type of IPV were more likely to have been ever tested for HIV compared to women with no IPV history. However, nearly half of those reporting IPV, even though at greater risk for HIV infection, had never been tested. Additional efforts are needed to address barriers to testing in this group. JF - AIDS and Behavior AU - Nasrullah, Muazzam AU - Oraka, Emeka AU - Breiding, Mathew J AU - Chavez, Pollyanna R AD - Division of HIV/AIDS Prevention, National Center for HIV, Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road, Mailstop E46, Atlanta, GA, 30333, USA, snasrullah@cdc.gov Y1 - 2013/09// PY - 2013 DA - Sep 2013 SP - 2521 EP - 2527 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 17 IS - 7 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Risk Abstracts KW - Acquired immune deficiency syndrome KW - USA KW - Human immunodeficiency virus KW - Aggression KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1434034331?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=HIV+Testing+and+Intimate+Partner+Violence+Among+Non-Pregnant+Women+in+15+US+States%2FTerritories%3A+Findings+from+Behavioral+Risk+Factor+Surveillance+System+Survey+Data&rft.au=Nasrullah%2C+Muazzam%3BOraka%2C+Emeka%3BBreiding%2C+Mathew+J%3BChavez%2C+Pollyanna+R&rft.aulast=Nasrullah&rft.aufirst=Muazzam&rft.date=2013-09-01&rft.volume=17&rft.issue=7&rft.spage=2521&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-013-0493-1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-09-01 N1 - Number of references - 1 N1 - Last updated - 2014-03-10 N1 - SubjectsTermNotLitGenreText - Aggression; Human immunodeficiency virus; USA DO - http://dx.doi.org/10.1007/s10461-013-0493-1 ER - TY - JOUR T1 - Medications in the first trimester of pregnancy: most common exposures and critical gaps in understanding fetal risk. AN - 1426748296; 23893932 AB - To determine which medications are most commonly used by women in the first trimester of pregnancy and identify the critical gaps in information about fetal risk for those medications. Self-reported first-trimester medication use was assessed among women delivering liveborn infants without birth defects and serving as control mothers in two large case-control studies of major birth defects. The Teratology Information System (TERIS) expert Advisory Board ratings of quality and quantity of data available to assess fetal risk were reviewed to identify information gaps. Responses from 5381 mothers identified 54 different medication components used in the first trimester by at least 0.5% of pregnant women, including 31 prescription and 23 over-the-counter medications. The most commonly used prescription medication components reported were progestins from oral contraceptives, amoxicillin, progesterone, albuterol, promethazine, and estrogenic compounds. The most commonly used over-the-counter medication components reported were acetaminophen, ibuprofen, docusate, pseudoephedrine, aspirin, and naproxen. Among the 54 most commonly used medications, only two had "Good to Excellent" data available to assess teratogenic risk in humans, based on the TERIS review. For most medications commonly used in pregnancy, there are insufficient data available to characterize the fetal risk fully, limiting the opportunity for informed clinical decisions about the best management of acute and chronic disorders during pregnancy. Future research efforts should be directed at these critical knowledge gaps. Copyright © 2013 John Wiley & Sons, Ltd. JF - Pharmacoepidemiology and drug safety AU - Thorpe, Phoebe G AU - Gilboa, Suzanne M AU - Hernandez-Diaz, Sonia AU - Lind, Jennifer AU - Cragan, Janet D AU - Briggs, Gerald AU - Kweder, Sandra AU - Friedman, Jan M AU - Mitchell, Allen A AU - Honein, Margaret A AU - National Birth Defects Prevention Study AD - Division of Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. pht1@cdc.gov ; National Birth Defects Prevention Study Y1 - 2013/09// PY - 2013 DA - September 2013 SP - 1013 EP - 1018 VL - 22 IS - 9 KW - Nonprescription Drugs KW - 0 KW - Prescription Drugs KW - Index Medicus KW - medication KW - pharmacoepidemiology KW - teratogen KW - pregnancy KW - fetal risk KW - United States KW - Risk KW - Pregnancy Trimester, First KW - Adverse Drug Reaction Reporting Systems KW - Humans KW - Surveys and Questionnaires KW - Pharmacoepidemiology KW - Female KW - Pregnancy KW - Drug Prescriptions -- statistics & numerical data KW - Maternal Exposure -- adverse effects KW - Nonprescription Drugs -- adverse effects KW - Prescription Drugs -- adverse effects KW - Prescription Drugs -- administration & dosage KW - Drug Utilization Review -- trends KW - Nonprescription Drugs -- therapeutic use KW - Maternal Exposure -- statistics & numerical data KW - Nonprescription Drugs -- administration & dosage KW - Health Knowledge, Attitudes, Practice KW - Fetal Development -- drug effects KW - Drug Utilization Review -- statistics & numerical data KW - Prescription Drugs -- therapeutic use UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1426748296?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Pharmacoepidemiology+and+drug+safety&rft.atitle=Medications+in+the+first+trimester+of+pregnancy%3A+most+common+exposures+and+critical+gaps+in+understanding+fetal+risk.&rft.au=Thorpe%2C+Phoebe+G%3BGilboa%2C+Suzanne+M%3BHernandez-Diaz%2C+Sonia%3BLind%2C+Jennifer%3BCragan%2C+Janet+D%3BBriggs%2C+Gerald%3BKweder%2C+Sandra%3BFriedman%2C+Jan+M%3BMitchell%2C+Allen+A%3BHonein%2C+Margaret+A%3BNational+Birth+Defects+Prevention+Study&rft.aulast=Thorpe&rft.aufirst=Phoebe&rft.date=2013-09-01&rft.volume=22&rft.issue=9&rft.spage=1013&rft.isbn=&rft.btitle=&rft.title=Pharmacoepidemiology+and+drug+safety&rft.issn=1099-1557&rft_id=info:doi/10.1002%2Fpds.3495 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2014-03-14 N1 - Date created - 2013-08-20 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Obstet Gynecol. 2002 Sep;100(3):465-73 [12220765] Am J Epidemiol. 1986 Apr;123(4):670-6 [3953545] J Womens Health (Larchmt). 2005 Jun;14(5):382-6 [15989409] Am J Obstet Gynecol. 2005 Sep;193(3 Pt 1):771-7 [16150273] Am J Obstet Gynecol. 2011 Jul;205(1):51.e1-8 [21514558] J Womens Health (Larchmt). 2008 Sep;17(7):1073-80 [18774892] Birth Defects Res A Clin Mol Teratol. 2008 Sep;82(9):605-9 [18704917] Obstet Gynecol. 2011 Jun;117(6):1484-5 [21606771] Am J Med Genet C Semin Med Genet. 2011 Aug 15;157C(3):175-82 [21766440] Pharmacoeconomics. 2006;24(3):233-6 [16519545] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1002/pds.3495 ER - TY - JOUR T1 - Intrapartum antibiotic prophylaxis for the prevention of perinatal group B streptococcal disease: Experience in the United States and implications for a potential group B streptococcal vaccine AN - 1443369666; 18663345 AB - Group B Streptococcus (GBS) emerged as the leading cause of newborn infection in the United States in the 1970s. In the 1980s clinical trials demonstrated that giving intrapartum intravenous ampicillin or penicillin to mothers at risk was highly effective at preventing invasive GBS disease in the first week of life (early-onset). In 1996, the first national guidelines for the prevention of perinatal GBS disease were issued; these recommended either antenatal screening for GBS colonization and intrapartum antimicrobial prophylaxis (IAP) to colonized women, or targeting IAP to women with certain obstetric risk factors during labor. In 2002, revised guidelines recommended universal antenatal GBS screening. A multistate population-based review of labor and delivery records in 2003-2004 found 85% of women had documented antenatal GBS screening; 98% of screened women had a colonization result available at labor. However, missed opportunities for prevention were identified among women delivering preterm and among those with penicillin allergy, and more false negative GBS screening results were observed than expected. The incidence of invasive early-onset GBS disease decreased by more than 80% from 1.8 cases/1000 live births in the early 1990s to 0.26 cases/1000 live births in 2010; from 1994 to 2010 we estimate that over 70,000 cases of EOGBS invasive disease were prevented in the United States. IAP effectiveness is similar and high among term (91%) and preterm (86%) infants when first line therapy is received for at least 4 h. However, early-onset disease incidence among preterm infants remains twice that of term infants; moreover disease among infants after the first week of life (late-onset disease) has not been impacted by IAP. The US experience demonstrates that universal screening and IAP for GBS-colonized women comprise a highly effective strategy against early-onset GBS infections. Maximizing adherence to recommended practices holds promise to further reduce the burden of early-onset GBS disease. Yet there are also inherent limitations to universal screening and IAP. Some of these could potentially be addressed by an efficacious maternal GBS vaccine. JF - Vaccine AU - Schrag, S J AU - Verani, J R AD - MS C25, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA 30333, USA, zha6@cdc.gov Y1 - 2013/08/28/ PY - 2013 DA - 2013 Aug 28 SP - D20 EP - D26 VL - 31 SN - 0264-410X, 0264-410X KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Streptococcus KW - Intravenous administration KW - Age KW - Ampicillin KW - Antibiotics KW - Infection KW - Clinical trials KW - Penicillin KW - Antimicrobial agents KW - IAP protein KW - Colonization KW - Hypersensitivity KW - Risk factors KW - Prophylaxis KW - Vaccines KW - Neonates KW - Obstetrics KW - Infants KW - F 06925:Hypersensitivity KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1443369666?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Intrapartum+antibiotic+prophylaxis+for+the+prevention+of+perinatal+group+B+streptococcal+disease%3A+Experience+in+the+United+States+and+implications+for+a+potential+group+B+streptococcal+vaccine&rft.au=Schrag%2C+S+J%3BVerani%2C+J+R&rft.aulast=Schrag&rft.aufirst=S&rft.date=2013-08-28&rft.volume=31&rft.issue=&rft.spage=D20&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-10-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Age; Intravenous administration; Ampicillin; Antibiotics; Infection; Clinical trials; Penicillin; Antimicrobial agents; IAP protein; Colonization; Hypersensitivity; Risk factors; Prophylaxis; Neonates; Vaccines; Obstetrics; Infants; Streptococcus ER - TY - JOUR T1 - Serum concentrations of an aflatoxin-albumin adduct in the National Health and Nutrition Examination Survey (NHANES) 1999-2000. AN - 1364707923; 23611894 AB - During 1998, weather conditions in the United States favored the growth of Aspergillus species leading to widespread contamination of Midwestern and Southern corn with hepatotoxic and hepatocarcinogenic aflatoxins. We designed a study to provide the first national prevalence estimate of aflatoxin exposure using the National Health and Nutrition Examination Survey (NHANES), a representative cross-sectional survey of the noninstitutionalized civilian population of the US. Isotope dilution liquid chromatography-tandem mass spectrometry was used to quantitate serum concentrations of aflatoxin B1-lysine in a one-third random subset of participants from NHANES 1999-2000. About 1% of the U.S. population had detectable levels (≥0.02μg/l) of aflatoxin B1-lysine. Of those with detectable levels, the geometric mean (95% confidence interval) was 0.038 (0.024-0.060) μg/l (equivalent to 0.842 (0.530-1.34) pg/mg albumin). The highest value was 0.2μg/l (4.43pg/mg albumin). Based on liver function biomarkers, there was no evidence of increased liver dysfunction in these persons. During a time when exposure to aflatoxins in food products might have been expected to be increased, we identified few exposed persons. Although none of the subgroup analyses provided reliable estimates due to high relative standard errors, they suggested that additional targeted surveillance may be warranted. Published by Elsevier B.V. JF - Clinica chimica acta; international journal of clinical chemistry AU - Schleicher, Rosemary L AU - McCoy, Leslie F AU - Powers, Carissa D AU - Sternberg, Maya R AU - Pfeiffer, Christine M AD - Nutritional Biomarkers Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, United States. Zwa5@cdc.gov Y1 - 2013/08/23/ PY - 2013 DA - 2013 Aug 23 SP - 46 EP - 50 VL - 423 KW - Aflatoxins KW - 0 KW - Albumins KW - aflatoxin-albumin adduct KW - Index Medicus KW - Young Adult KW - Mass Spectrometry KW - Humans KW - Adult KW - Chromatography, Liquid KW - Child KW - Adolescent KW - Male KW - Female KW - Population Surveillance KW - Nutrition Surveys KW - Aflatoxins -- blood UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1364707923?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinica+chimica+acta%3B+international+journal+of+clinical+chemistry&rft.atitle=Serum+concentrations+of+an+aflatoxin-albumin+adduct+in+the+National+Health+and+Nutrition+Examination+Survey+%28NHANES%29+1999-2000.&rft.au=Schleicher%2C+Rosemary+L%3BMcCoy%2C+Leslie+F%3BPowers%2C+Carissa+D%3BSternberg%2C+Maya+R%3BPfeiffer%2C+Christine+M&rft.aulast=Schleicher&rft.aufirst=Rosemary&rft.date=2013-08-23&rft.volume=423&rft.issue=&rft.spage=46&rft.isbn=&rft.btitle=&rft.title=Clinica+chimica+acta%3B+international+journal+of+clinical+chemistry&rft.issn=1873-3492&rft_id=info:doi/10.1016%2Fj.cca.2013.04.011 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2014-01-07 N1 - Date created - 2013-06-03 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1016/j.cca.2013.04.011 ER - TY - JOUR T1 - Interlaboratory Agreement of Pulsed-Field Gel Electrophoresis Identification of Leptospira Serovars AN - 1647007156; 21172201 AB - Leptospirosis may be caused by > 250 Leptospira serovars. Serovar classification is a complex task that most laboratories cannot perform. We assessed the interlaboratory reproducibility of a pulsed-field gel electrophoresis (PFGE) identification technique developed by the Centers for Disease Control and Prevention (CDC). Blinded exchange of 93 Leptospiraceae strains occurred between San Antonio Military Medical Center (SAMMC) and the CDC. PFGE was performed and gel images were analyzed and compared with patterns present in each laboratory's database (CDC database: > 800 strain patterns; SAMMC database: > 300 strain patterns). Overall, 93.7% (74 of 79) of strains present in each receiving laboratory's database were correctly identified. Five isolates were misidentified, and two isolates did not match serovar PFGE patterns in the receiving laboratory's database. Patterns for these seven isolates were identical between laboratories; four serovars represented misidentified reference strains. The PFGE methodology studied showed excellent interlaboratory reproducibility, enabling standardization and data sharing between laboratories. JF - American Journal of Tropical Medicine and Hygiene AU - Mende, Katrin AU - Galloway, Renee L AU - Becker, Sara J AU - Beckius, Miriam L AU - Murray, Clinton K AU - Hospenthal, Duane R AD - Departments of Medicine and Clinical Investigation, San Antonio Military Medical Center, Fort Sam Houston, Texas; Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland; National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia; Department of Medicine, Wright-Patterson Medical Center, Wright-Patterson Air Force Base, Ohio, drhospenthal@gmail.com Y1 - 2013/08// PY - 2013 DA - August 2013 SP - 380 EP - 384 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 89 IS - 2 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts KW - Electrophoresis KW - Data processing KW - Leptospirosis KW - Leptospira KW - Disease control KW - Databases KW - Standardization KW - Prevention KW - Classification KW - Pulsed-field gel electrophoresis KW - Standards KW - Military KW - K 03330:Biochemistry KW - H 1000:Occupational Safety and Health KW - J 02300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1647007156?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Interlaboratory+Agreement+of+Pulsed-Field+Gel+Electrophoresis+Identification+of+Leptospira+Serovars&rft.au=Mende%2C+Katrin%3BGalloway%2C+Renee+L%3BBecker%2C+Sara+J%3BBeckius%2C+Miriam+L%3BMurray%2C+Clinton+K%3BHospenthal%2C+Duane+R&rft.aulast=Mende&rft.aufirst=Katrin&rft.date=2013-08-01&rft.volume=89&rft.issue=2&rft.spage=380&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.12-0768 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Standardization; Databases; Data processing; Classification; Leptospirosis; Disease control; Pulsed-field gel electrophoresis; Prevention; Electrophoresis; Standards; Military; Leptospira DO - http://dx.doi.org/10.4269/ajtmh.12-0768 ER - TY - JOUR T1 - The utility of stool cultures for diagnosing tuberculosis in people living with the human immunodeficiency virus AN - 1430850969; 18328357 AB - BACKGROUND: Delayed diagnosis of tuberculosis (TB) increases mortality. OBJECTIVE: To evaluate whether stool culture improves the diagnosis of TB in people living with the human immunodeficiency virus (PLHFV). DESIGN: We analysed cross-sectional data of TB diagnosis in PLHIV in Cambodia, Thailand and Viet Nam. Logistic regression was used to assess the association between positive stool culture and TB, and to calculate the incremental yield of stool culture. RESULTS: A total of 1693 PLHIV were enrolled with a stool culture result. Of 228 PLHIV with culture-confirmed TB from any site, 101 (44%) had a positive stool culture; of these, 91 (90%) had pulmonary TB (PTB). After adjusting for confounding factors, a positive stool culture was associated with smear-negative (odds ratio [OR] 26, 95% confidence interval [CI] 12-58), moderately smear-positive (OR 60, 95%CI 23-159) and highly smear-positive (OR 179, 95%CI 59-546) PTB compared with no PTB. No statistically significant association existed with extra-pulmonary TB compared with no extra-pulmonary TB (OR 2, 95%CI 1-5). The incremental yield of one stool culture above two sputum cultures (5%, 95%CI 3-8) was comparable to an additional sputum culture (7%, 95%CI 4-11). CONCLUSION: Nearly half of the PLHIV with TB had a positive stool culture that was strongly associated with PTB. Stool cultures may be used to diagnose TB in PLHIV. JF - International Journal of Tuberculosis and Lung Disease AU - Oramasionwu, GE AU - Heilig, C M AU - Udomsantisuk, N AU - Kimerling, ME AU - Eng, B AU - Nguyen, H D AU - Thai, S AU - Keo, C AU - McCarthy, K D AU - Varma, J K AU - Cain, K P AD - Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, 1600 Clifton Road NE, MS E-10, Atlanta, GA 30333, USA, iyo8@cdc.gov Y1 - 2013/08// PY - 2013 DA - Aug 2013 SP - 1023 EP - 1028 PB - International Union Against Tuberculosis and Lung Disease VL - 17 IS - 8 SN - 1027-3719, 1027-3719 KW - Virology & AIDS Abstracts; Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Data processing KW - Human immunodeficiency virus KW - Tuberculosis KW - V 22360:AIDS and HIV KW - J 02400:Human Diseases KW - F 06910:Microorganisms & Parasites UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1430850969?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=The+utility+of+stool+cultures+for+diagnosing+tuberculosis+in+people+living+with+the+human+immunodeficiency+virus&rft.au=Oramasionwu%2C+GE%3BHeilig%2C+C+M%3BUdomsantisuk%2C+N%3BKimerling%2C+ME%3BEng%2C+B%3BNguyen%2C+H+D%3BThai%2C+S%3BKeo%2C+C%3BMcCarthy%2C+K+D%3BVarma%2C+J+K%3BCain%2C+K+P&rft.aulast=Oramasionwu&rft.aufirst=GE&rft.date=2013-08-01&rft.volume=17&rft.issue=8&rft.spage=1023&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-09-01 N1 - Last updated - 2014-03-10 N1 - SubjectsTermNotLitGenreText - Tuberculosis; Human immunodeficiency virus ER - TY - JOUR T1 - Mortality from a tornado outbreak, Alabama, April 27, 2011. AN - 1429845870; 23763401 AB - We describe the demographics of the decedents from the tornado outbreak in Alabama on April 27, 2011; examine the circumstances of death surrounding these fatalities; and identify measures to prevent future tornado-related fatalities. We collected information about the decedents from death certificates, disaster-related mortality surveillance, and interview data collected by American Red Cross volunteers from the decedent's families. We describe demographic characteristics, circumstances and causes of death, and sheltering behaviors before death. Of the 247 fatalities, females and older adults were at highest risk for tornado-related deaths. Most deaths were directly related to the tornadoes, on scene, and trauma-related. The majority of the deceased were indoors in single-family homes. Word of mouth was the most common warning mechanism. This tornado event was the third deadliest in recent US history. Our findings support the need for local community shelters, enhanced messaging to inform the public of shelter locations, and encouragement of word-of-mouth warnings and personal and family preparedness planning, with a special focus on assisting vulnerable individuals in taking shelter. JF - American journal of public health AU - Chiu, Cindy H AU - Schnall, Amy H AU - Mertzlufft, Caitlin E AU - Noe, Rebecca S AU - Wolkin, Amy F AU - Spears, Jeanne AU - Casey-Lockyer, Mary AU - Vagi, Sara J AD - Health Studies Branch, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway, Mailstop F-60, Atlanta, GA 30341, USA. cchiu@cdc.gov Y1 - 2013/08// PY - 2013 DA - August 2013 SP - e52 EP - e58 VL - 103 IS - 8 KW - Abridged Index Medicus KW - Index Medicus KW - Alabama -- epidemiology KW - Age Factors KW - Sex Factors KW - Risk Factors KW - Humans KW - Male KW - Female KW - Population Surveillance KW - Age Distribution KW - Disasters -- statistics & numerical data KW - Tornadoes KW - Wounds and Injuries -- mortality UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1429845870?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+journal+of+public+health&rft.atitle=Mortality+from+a+tornado+outbreak%2C+Alabama%2C+April+27%2C+2011.&rft.au=Chiu%2C+Cindy+H%3BSchnall%2C+Amy+H%3BMertzlufft%2C+Caitlin+E%3BNoe%2C+Rebecca+S%3BWolkin%2C+Amy+F%3BSpears%2C+Jeanne%3BCasey-Lockyer%2C+Mary%3BVagi%2C+Sara+J&rft.aulast=Chiu&rft.aufirst=Cindy&rft.date=2013-08-01&rft.volume=103&rft.issue=8&rft.spage=e52&rft.isbn=&rft.btitle=&rft.title=American+journal+of+public+health&rft.issn=1541-0048&rft_id=info:doi/10.2105%2FAJPH.2013.301291 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2013-09-19 N1 - Date created - 2013-07-11 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Am J Epidemiol. 1989 Dec;130(6):1209-18 [2589312] MMWR Morb Mortal Wkly Rep. 1991 Jan 18;40(2):33-6 [1898669] Int J Epidemiol. 1990 Dec;19(4):1051-6 [2083989] MMWR Morb Mortal Wkly Rep. 1992 Mar 13;41(10):181-3 [1538688] MMWR Morb Mortal Wkly Rep. 1997 May 16;46(19):412-6 [9162841] MMWR Morb Mortal Wkly Rep. 2012 Jul 20;61(28):529-33 [22810266] Disasters. 2011 Apr;35(2):329-45 [21073669] Int J Epidemiol. 1999 Dec;28(6):1124-9 [10661657] J Trauma. 1966 May;6(3):353-61 [5934279] MMWR Morb Mortal Wkly Rep. 1986 Apr 11;35(14):233-5 [3083227] MMWR Morb Mortal Wkly Rep. 1988 Aug 5;37(30):454-6, 461 [3135473] Am J Epidemiol. 2005 Jun 15;161(12):1144-50 [15937023] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.2105/AJPH.2013.301291 ER - TY - JOUR T1 - Food Availability en Route to School and Anthropometric Change in Urban Children AN - 1427001987; 18325994 AB - This study examined food availability along children's paths to and from elementary school, and associations with change in body mass index (BMI) and waist circumference over 1 year. Secondary data from 319 children aged 8-13 years from the "Multiple Opportunities to Reach Excellence" Project was used. Child anthropometry and demographic variables were obtained at baseline (2007) and 1 year follow-up. Food outlet locations (n=1,410) were obtained from the Baltimore City Health Department and validated by ground-truthing. Secondary data on healthy food availability within select food stores in Baltimore City in 2007 were obtained via a validated food environment assessment measure, the Nutrition Environments Measures Study. Multilevel models were used to examine associations between availability of healthy food and number of various food outlets along paths to school and child anthropometric change over 1 year. Controlling for individual-, neighborhood-, and school-level characteristics, results indicated that higher healthy food availability within a 100 m buffer of paths to school was associated with 0.15 kg/m super(2) lower BMI gain (p=0.015) and 0.47 cm smaller waist circumference gain (p=0.037) over 1 year. Although prior research has illuminated the importance of healthy food choices within school and home environments, the current study suggests that exposure to the food environment along paths to school should be further explored in relation to child health outcomes. JF - Journal of Urban Health AU - Rossen, Lauren M AU - Curriero, Frank C AU - Cooley-Strickland, Michele AU - Pollack, Keshia M AD - Analysis and Epidemiology, National Center for Health Statistics, Centers for Disease Control and Prevention, 3311 Toledo Rd, Room 6114, Hyattsville, MD, 20782, USA, lrossen@cdc.gov Y1 - 2013/08// PY - 2013 DA - Aug 2013 SP - 653 EP - 666 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 90 IS - 4 SN - 1099-3460, 1099-3460 KW - Health & Safety Science Abstracts KW - Body mass KW - Schools KW - USA, Maryland, Baltimore KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1427001987?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Urban+Health&rft.atitle=Food+Availability+en+Route+to+School+and+Anthropometric+Change+in+Urban+Children&rft.au=Rossen%2C+Lauren+M%3BCurriero%2C+Frank+C%3BCooley-Strickland%2C+Michele%3BPollack%2C+Keshia+M&rft.aulast=Rossen&rft.aufirst=Lauren&rft.date=2013-08-01&rft.volume=90&rft.issue=4&rft.spage=653&rft.isbn=&rft.btitle=&rft.title=Journal+of+Urban+Health&rft.issn=10993460&rft_id=info:doi/10.1007%2Fs11524-012-9785-4 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-01 N1 - Number of references - 1 N1 - Last updated - 2014-03-10 N1 - SubjectsTermNotLitGenreText - Schools; USA, Maryland, Baltimore DO - http://dx.doi.org/10.1007/s11524-012-9785-4 ER - TY - JOUR T1 - Comparative analysis of Shigella sonnei biotype g isolated from paediatric populations in Egypt, 1999-2005 AN - 1419364526; 18273373 AB - Strain characteristics of 51 Shigella sonnei isolates obtained from children seeking medical care (MC) and 48 isolates recovered during a prospective diarrhoea birth cohort (BC) study were compared. Biochemical characterization and antibiotic susceptibility testing determined that all S. sonnei isolates were biotype g and multidrug-resistant. Plasmid profiling identified 15 closely related patterns and XbaI pulsed-field gel electrophoresis confirmed the high degree of genetic similarity between isolates. All S. sonnei isolates harboured ipaH and class II integrase genes and 84.3 and 80% of the MC and BC isolates, respectively carried the sen gene. Neither the class I integrase nor the set gene was detected. Our results indicate that S. sonnei isolates associated with severe diarrhoea were indistinguishable from those associated with mild diarrhoea. Additional genetic tests with greater discrimination might offer an opportunity to determine genetic differences within the globally disseminating biotype g clone. JF - Epidemiology and Infection AU - Dejli, J AU - Nada, R A AU - Mansour, A AU - El-Moniem, A A AU - Wasfy, MO AU - Klena, J D AD - Clinical Trials and Military Studies Program, U.S. Naval Medical Research Unit No. 3, Cairo, Egypt, irc4@cn.cdc.gov Y1 - 2013/08// PY - 2013 DA - August 2013 SP - 1614 EP - 1624 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 141 IS - 8 SN - 0950-2688, 0950-2688 KW - Microbiology Abstracts B: Bacteriology; Water Resources Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Aqualine Abstracts; Health & Safety Science Abstracts KW - Egypt, Arab Rep. KW - Biotypes KW - Biochemistry KW - Drug resistance KW - Parturition KW - Antibiotics KW - Infection KW - Strain KW - set gene KW - Populations KW - Integrase KW - Testing Procedures KW - Clones KW - Electrophoresis KW - Diarrhea KW - Pediatrics KW - Profiling KW - Discrimination KW - Shigella KW - Children KW - Plasmids KW - Shigella sonnei KW - Epidemiology KW - Pulsed-field gel electrophoresis KW - SW 5010:Network design KW - Q1 08484:Species interactions: parasites and diseases KW - AQ 00008:Effects of Pollution KW - H 12000:Epidemiology and Public Health KW - Q5 08524:Public health, medicines, dangerous organisms KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1419364526?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Comparative+analysis+of+Shigella+sonnei+biotype+g+isolated+from+paediatric+populations+in+Egypt%2C+1999-2005&rft.au=Dejli%2C+J%3BNada%2C+R+A%3BMansour%2C+A%3BEl-Moniem%2C+A+A%3BWasfy%2C+MO%3BKlena%2C+J+D&rft.aulast=Dejli&rft.aufirst=J&rft.date=2013-08-01&rft.volume=141&rft.issue=8&rft.spage=1614&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268812002002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-01 N1 - Number of references - 56 N1 - Last updated - 2016-10-26 N1 - SubjectsTermNotLitGenreText - Clones; Epidemiology; Profiling; Parturition; Antibiotics; Plasmids; Diarrhea; Biotypes; Pediatrics; Drug resistance; Pulsed-field gel electrophoresis; Children; set gene; Integrase; Electrophoresis; Biochemistry; Discrimination; Testing Procedures; Shigella; Infection; Strain; Populations; Shigella sonnei; Egypt, Arab Rep. DO - http://dx.doi.org/10.1017/S0950268812002002 ER - TY - JOUR T1 - Understanding Knowledge, Attitudes, and Behaviors Related to Influenza and the Influenza Vaccine in US-Mexico Border Communities AN - 1412562551; 18246680 AB - Hispanics are less likely to receive the influenza vaccine compared to other racial and ethnic groups in the US. Hispanic residents of the US-Mexico border region may have differing health beliefs and behaviors, and their cross-border mobility impacts disease control. To assess beliefs and behaviors regarding influenza prevention and control among border populations, surveys were conducted at border clinics. Of 197 respondents, 34 % reported conditions for which vaccination is indicated, and travel to Mexico was common. Few (35 %) believed influenza could make them 'very sick', and 76 % believed they should take antibiotics to treat influenza. Influenza vaccine awareness was high, and considered important, but only 36 % reported recent vaccination. The belief that influenza vaccination is 'very important' was strongly associated with recent vaccination; "Didn't think about it" was the most common reason for being un-vaccinated. Misconceptions about influenza risk, prevention and treatment were common in this Hispanic border population; improved educational efforts and reminder systems could impact vaccination behaviors. JF - Journal of Immigrant and Minority Health AU - Phippard, Alba E AU - Kimura, Akiko C AU - Lopez, Karla AU - Kriner, Paula AD - Border Infectious Disease Surveillance, San Diego County Office of Border Health, 3851 Rosecrans St, Suite 715, San Diego, CA, 92110, USA, ign7@cdc.gov Y1 - 2013/08// PY - 2013 DA - Aug 2013 SP - 741 EP - 746 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 15 IS - 4 SN - 1557-1912, 1557-1912 KW - Virology & AIDS Abstracts; Risk Abstracts KW - Antibiotics KW - Influenza KW - Mexico KW - V 22490:Miscellaneous KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1412562551?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Immigrant+and+Minority+Health&rft.atitle=Understanding+Knowledge%2C+Attitudes%2C+and+Behaviors+Related+to+Influenza+and+the+Influenza+Vaccine+in+US-Mexico+Border+Communities&rft.au=Phippard%2C+Alba+E%3BKimura%2C+Akiko+C%3BLopez%2C+Karla%3BKriner%2C+Paula&rft.aulast=Phippard&rft.aufirst=Alba&rft.date=2013-08-01&rft.volume=15&rft.issue=4&rft.spage=741&rft.isbn=&rft.btitle=&rft.title=Journal+of+Immigrant+and+Minority+Health&rft.issn=15571912&rft_id=info:doi/10.1007%2Fs10903-012-9652-0 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-07-01 N1 - Number of references - 1 N1 - Last updated - 2014-03-10 N1 - SubjectsTermNotLitGenreText - Influenza; Mexico DO - http://dx.doi.org/10.1007/s10903-012-9652-0 ER - TY - JOUR T1 - Effectiveness of the 7-valent pneumococcal conjugate vaccine against vaccine-type invasive disease among children in Uruguay: An evaluation using existing data AN - 1443369474; 18663029 AB - The 7-valent pneumococcal conjugate vaccine (PCV7) was introduced into the routine immunization program in Uruguay in March 2008 with a 2-dose primary series (given at 2 and 4 months) plus a booster (at 12 months) and a catch-up campaign (two doses given at 15 and 17 months). We used a case-control methodology and existing laboratory surveillance and immunization registry data from Uruguay to evaluate PCV7 effectiveness against vaccine-type invasive pneumococcal disease (VT-IPD). Cases of VT-IPD (with pneumococcus obtained from a normally sterile site) were identified through the National Reference Laboratory. Age- and neighborhood-matched controls were obtained through a national immunization registry in which all children are enrolled at birth regardless of vaccine receipt; all eligible controls were included. Immunization status of cases and controls was assessed through the immunization registry, and conditional logistic regression was used to calculate PCV7 effectiveness. Between April 2008 and February 2010,44 cases of VT-IPD among children < 5 years were identified; 43 (98%) of those children were located in the registry. Among located case patients, 7 (16.3%) were age-eligible to have received at least one dose of PCV7. A total of 637 matched controls were included. Vaccine effectiveness was 91.3% (95% CI: 46.4,98.6) for greater than or equal to 1 PCV7 doses and 94.8% (95% CI: 43.1,99.5) for greater than or equal to 2 PCV7 doses. Using existing data we demonstrated high effectiveness of PCV7 against VT-IPD in Uruguay-a middle-income country using a 2-dose primary series plus a booster dose and a limited catch-up campaign. These data also highlight the utility of surveillance and high-quality immunization registries for evaluating the effectiveness of vaccines. JF - Vaccine AU - Picon, T AU - Alonso, L AU - Gabarrot, G G AU - Speranza, N AU - Casas, M AU - Arrieta, F AU - Camou, T AU - Rosa, R AU - De Oliveira, LH AU - Verani, J R AD - Respiratory Diseases Branch, Division of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, USA, jverani@cdc.gov Y1 - 2013/07/02/ PY - 2013 DA - 2013 Jul 02 SP - C109 EP - C113 VL - 31 SN - 0264-410X, 0264-410X KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Birth KW - Streptococcus pneumoniae KW - Immunization KW - F:06905 KW - J:02350 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1443369474?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Effectiveness+of+the+7-valent+pneumococcal+conjugate+vaccine+against+vaccine-type+invasive+disease+among+children+in+Uruguay%3A+An+evaluation+using+existing+data&rft.au=Picon%2C+T%3BAlonso%2C+L%3BGabarrot%2C+G+G%3BSperanza%2C+N%3BCasas%2C+M%3BArrieta%2C+F%3BCamou%2C+T%3BRosa%2C+R%3BDe+Oliveira%2C+LH%3BVerani%2C+J+R&rft.aulast=Picon&rft.aufirst=T&rft.date=2013-07-02&rft.volume=31&rft.issue=&rft.spage=C109&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-10-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Immunization; Streptococcus pneumoniae ER - TY - JOUR T1 - The effect of performance indicator category on estimates of intervention effectiveness AN - 1692280314; 2011-463188 AB - Background A challenge for systematic reviews on improving health worker performance is that included studies often use different performance indicators, and the validity of comparing interventions with different indicators is unclear. One potential solution is to adjust comparisons by indicator category, with categories based on steps of the case-management process that can be easily recognized (assessment of symptoms, treatment etc.) and that might require different levels of effort to bring about improvements. However, this approach would only be useful if intervention effect sizes varied by indicator category. To explore this approach, studies were analyzed that evaluated the Integrated Management of Childhood Illness (IMCI) strategy. Methods Performance indicators were grouped into four categories: patient assessment, diagnosis, treatment and counseling. An effect size of IMCI was calculated for each indicator. Linear regression modeling was used to test for differences among the mean effect sizes of the indicator categories. Results Six studies were included, with data from 3136 ill child consultations. Mean effect sizes for 63 assessment indicators, 12 diagnosis indicators, 31 treatment indicators and 34 counseling indicators were 50.9 percentage-points (%-points), 44.7, 36.5 and 46.6%-points, respectively. After adjusting for baseline indicator value, compared with the assessment mean effect size, the diagnosis mean was 7.3%-points lower (P = 0.23), the treatment mean was 15.2%-points lower (P = 0.0004) and the counseling mean was 12.9%-points lower (P = 0.0027). Conclusion Adjusting the results of systematic reviews for indicator category and baseline indicator value might be useful for improving the validity of intervention comparisons. Adapted from the source document. JF - International Journal for Quality in Health Care AU - Rowe, Alexander K AD - Centers for Disease Control and Prevention, Mailstop A06, 1600 Clifton Road NE, Atlanta, GA 30333, USA axr9@cdc.gov Y1 - 2013/07// PY - 2013 DA - July 2013 SP - 331 EP - 339 PB - Oxford University Press, UK VL - 25 IS - 3 SN - 1353-4505, 1353-4505 KW - Social conditions and policy - Psychology KW - Health conditions and policy - Health and health policy KW - child health developing country health services research methods quality improvement systematic reviews KW - Health policy KW - Patients KW - Counseling KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1692280314?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+for+Quality+in+Health+Care&rft.atitle=The+effect+of+performance+indicator+category+on+estimates+of+intervention+effectiveness&rft.au=Rowe%2C+Alexander+K&rft.aulast=Rowe&rft.aufirst=Alexander&rft.date=2013-07-01&rft.volume=25&rft.issue=3&rft.spage=331&rft.isbn=&rft.btitle=&rft.title=International+Journal+for+Quality+in+Health+Care&rft.issn=13534505&rft_id=info:doi/10.1093%2Fintqhc%2Fmzt030 LA - English DB - PAIS Index N1 - Date revised - 2015-07-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Counseling; Patients; Health policy DO - http://dx.doi.org/10.1093/intqhc/mzt030 ER - TY - JOUR T1 - It is Possible: Availability of Lymphedema Case Management in each Health Facility in Togo. Program Description, Evaluation, and Lessons Learned AN - 1647016046; 21172132 AB - Lymphatic filariasis (LF) is a vector-borne parasitic disease that can clinically manifest as disabling lymphedema. Although the LF elimination program aims to reduce disability and to interrupt transmission, there has been a scarcity of disease morbidity management programs, particularly on a national scale. This report describes the implementation of the first nationwide LF lymphedema management program. The program, which was initiated in Togo in 2007, focuses on patient behavioral change. Its goal is two-fold: to achieve a sustainable program on a national-scale, and to serve as a model for other countries. The adherence rate to the proposed World Health Organization treatment of washing, exercise, and leg elevation was more than 70% after three years of the program, resulting in a stabilization of the lymphedema stage and a slight decrease in reported acute attacks among program participants. Health staff and patients consider the program successful in reaching and educating the patients. After the external funding ended, the morbidity management program is maintained through routine Ministry of Health activities. JF - American Journal of Tropical Medicine and Hygiene AU - Mathieu, Els AU - Dorkenoo, Ameyo M AU - Datagni, Michael AU - Cantey, Paul T AU - Morgah, Kodjo AU - Harvey, Kira AU - Ziperstein, Joshua AU - Drexler, Naomi AU - Chapleau, Gina AU - Sodahlon, Yao AD - Ministry of Health, Lome Togo; Emory University, Atlanta, Georgia; Mectizan Donation Program, Decatur, Georgia; Centers for Disease Control and Prevention, 4770 Buford Highway NE, Atlanta, GA 30341, emm7@cdc.gov Y1 - 2013/07// PY - 2013 DA - July 2013 SP - 16 EP - 22 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 89 IS - 1 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Sustainability Science Abstracts; Health & Safety Science Abstracts KW - Filariasis KW - Sustainable development KW - Togo KW - Morbidity KW - Disease transmission KW - Physical training KW - Models KW - Lymphedema KW - Leg KW - Disabilities KW - Scarcity KW - Parasitic diseases KW - M3 1010:Issues in Sustainable Development KW - K 03400:Human Diseases KW - J 02400:Human Diseases KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1647016046?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=It+is+Possible%3A+Availability+of+Lymphedema+Case+Management+in+each+Health+Facility+in+Togo.+Program+Description%2C+Evaluation%2C+and+Lessons+Learned&rft.au=Mathieu%2C+Els%3BDorkenoo%2C+Ameyo+M%3BDatagni%2C+Michael%3BCantey%2C+Paul+T%3BMorgah%2C+Kodjo%3BHarvey%2C+Kira%3BZiperstein%2C+Joshua%3BDrexler%2C+Naomi%3BChapleau%2C+Gina%3BSodahlon%2C+Yao&rft.aulast=Mathieu&rft.aufirst=Els&rft.date=2013-07-01&rft.volume=89&rft.issue=1&rft.spage=16&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.12-0453 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Leg; Lymphedema; Filariasis; Parasitic diseases; Morbidity; Models; Physical training; Disease transmission; Disabilities; Scarcity; Sustainable development; Togo DO - http://dx.doi.org/10.4269/ajtmh.12-0453 ER - TY - JOUR T1 - Association between Mycobacterium tuberculosis lineage and time to sputum culture conversion AN - 1430854724; 18270316 AB - SETTING: Mycobacterium tuberculosis comprises four principal genetic lineages: one evolutionarily ancestral (Indo-Oceanic) and three modern. Whether response to tuberculosis (TB) treatment differs among the lineages is unknown. OBJECTIVE: To examine the association between M. tuberculosis lineage and time to sputum culture conversion in response to standard first-line drug therapy. DESIGN: We conducted an exploratory retrospective cohort analysis of time to sputum culture conversion among pulmonary tuberculosis (PTB) cases reported in the United States from 2004 to 2007. RESULTS: The analysis included 13 170 PTB cases with no documented resistance to first-line drugs who received a standard four-drug treatment regimen. Among cases with baseline positive sputum smear results, relative to cases with Euro-American lineage, cases with Indo-Oceanic lineage had higher adjusted hazards of sputum culture conversion (aHR 1.32, 95%CI 1.20-1.45), whereas cases with East-African-Indian or East-Asian lineage did not differ (aHR 1.05, 95%CI 0.88-1.25 and aHR 0.99, 95%CI 0.91-1.07, respectively). Among cases with baseline negative sputum smear results, time to sputum culture conversion did not differ by lineage. CONCLUSION: Although these results are exploratory, they suggest that the eradication of viable bacteria may occur sooner among cases with Indo-Oceanic lineage than among those with one of the three modern lineages. Prospective studies of time to sputum culture conversion by lineage are required. JF - International Journal of Tuberculosis and Lung Disease AU - Click, E S AU - Winston, CA AU - Oeltmann, JE AU - Moonan, P K AU - Kenzie, WRM AD - Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, MS E-10, Atlanta, GA 30333, USA, eoc9@cdc.gov Y1 - 2013/07// PY - 2013 DA - Jul 2013 SP - 878 EP - 884 PB - International Union Against Tuberculosis and Lung Disease VL - 17 IS - 7 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology KW - Drug resistance KW - Sputum KW - Mycobacterium tuberculosis KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1430854724?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Association+between+Mycobacterium+tuberculosis+lineage+and+time+to+sputum+culture+conversion&rft.au=Click%2C+E+S%3BWinston%2C+CA%3BOeltmann%2C+JE%3BMoonan%2C+P+K%3BKenzie%2C+WRM&rft.aulast=Click&rft.aufirst=E&rft.date=2013-07-01&rft.volume=17&rft.issue=7&rft.spage=878&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-09-01 N1 - Last updated - 2014-03-10 N1 - SubjectsTermNotLitGenreText - Sputum; Mycobacterium tuberculosis ER - TY - JOUR T1 - Lung-Function Impairment Among US Underground Coal Miners, 2005 to 2009: Geographic Patterns and Association With Coal Workers' Pneumoconiosis AN - 1427003731; 18328170 AB - Objective: To investigate contemporary geographic distributions of lung-function impairment and radiographic evidence of coal workers' pneumoconiosis (CWP) and their associations. Methods: From 2005 to 2009, 6373 underground coal miners completed a health survey, including spirometry testing and chest radiography. Coal workers' pneumoconiosis and progressive massive fibrosis were determined by NIOSH B readers, using the International Labour Office classification. Prevalences of CWP and spirometry less than lower normal limits were mapped by county, and their association assessed. Results: The prevalences of abnormal spirometry results and CWP were 13.1% and 4.0%, respectively. Counties with elevated prevalences for both the outcomes were located in contiguous areas of southeastern Kentucky, western Virginia, southern West Virginia, and eastern Pennsylvania. Prevalence of abnormal spirometry results increases with increasing category of simple CWP and progressive massive fibrosis. Conclusions: Abnormal spirometry in coal miners is associated with CWP; these two health outcomes have similar geographic distributions. JF - Journal of Occupational and Environmental Medicine AU - Wang, M L AU - Beeckman-Wagner, L-A AU - Wolfe, AL AU - Syamlal, G AU - Petsonk, EL AD - Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Mail Stop H-G900.2, 1095 Willowdale Rd, Morgantown, WV 26505, USA, mlw4@cdc.gov PY - 2013 SP - 846 EP - 850 VL - 55 IS - 7 SN - 1076-2752, 1076-2752 KW - Health & Safety Science Abstracts KW - USA, Kentucky KW - Classification KW - USA, Pennsylvania KW - Occupational safety KW - Pneumoconiosis KW - USA, Virginia KW - Coal KW - Mining KW - Radiography KW - USA, West Virginia KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1427003731?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Lung-Function+Impairment+Among+US+Underground+Coal+Miners%2C+2005+to+2009%3A+Geographic+Patterns+and+Association+With+Coal+Workers%27+Pneumoconiosis&rft.au=Wang%2C+M+L%3BBeeckman-Wagner%2C+L-A%3BWolfe%2C+AL%3BSyamlal%2C+G%3BPetsonk%2C+EL&rft.aulast=Wang&rft.aufirst=M&rft.date=2013-07-01&rft.volume=55&rft.issue=7&rft.spage=846&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e31828dc985 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-01 N1 - Last updated - 2015-12-23 N1 - SubjectsTermNotLitGenreText - Classification; Occupational safety; Pneumoconiosis; Radiography; Mining; Coal; USA, Kentucky; USA, Pennsylvania; USA, Virginia; USA, West Virginia DO - http://dx.doi.org/10.1097/JOM.0b013e31828dc985 ER - TY - JOUR T1 - Post-disaster reproductive health outcomes. AN - 1366578629; 22752348 AB - We examined methodological issues in studies of disaster-related effects on reproductive health outcomes and fertility among women of reproductive age and infants in the United States (US). We conducted a systematic literature review of 1,635 articles and reports published in peer-reviewed journals or by the government from January 1981 through December 2010. We classified the studies using three exposure types: (1) physical exposure to toxicants; (2) psychological trauma; and (3) general exposure to disaster. Fifteen articles met our inclusion criteria concerning research focus and design. Overall studies pertained to eight different disasters, with most (n = 6) focused on the World Trade Center attack. Only one study examined pregnancy loss, i.e., occurrence of spontaneous abortions post-disaster. Most studies focused on associations between disaster and adverse birth outcomes, but two studies pertained only to post-disaster fertility while another two examined it in addition to adverse birth outcomes. In most studies disaster-affected populations were assumed to have experienced psychological trauma, but exposure to trauma was measured in only four studies. Furthermore, effects of both physical exposure to toxicants and psychological trauma on disaster-affected populations were examined in only one study. Effects on birth outcomes were not consistently demonstrated, and study methodologies varied widely. Even so, these studies suggest an association between disasters and reproductive health and highlight the need for further studies to clarify associations. We postulate that post-disaster surveillance among pregnant women could improve our understanding of effects of disaster on the reproductive health of US pregnant women. JF - Maternal and child health journal AU - Zotti, Marianne E AU - Williams, Amy M AU - Robertson, McKaylee AU - Horney, Jennifer AU - Hsia, Jason AD - Division of Reproductive Health/NCCDPHP, Centers for Disease Control and Prevention, 4770 Buford Hwy, NE, MS-K22, Atlanta, GA 30341, USA. mbz1@cdc.gov Y1 - 2013/07// PY - 2013 DA - July 2013 SP - 783 EP - 796 VL - 17 IS - 5 KW - Index Medicus KW - United States KW - Fertility KW - Infant, Low Birth Weight KW - Humans KW - Female KW - Premature Birth KW - Pregnancy Outcome KW - Pregnancy KW - Stress Disorders, Post-Traumatic -- psychology KW - Reproductive Health KW - Disasters UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1366578629?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Maternal+and+child+health+journal&rft.atitle=Post-disaster+reproductive+health+outcomes.&rft.au=Zotti%2C+Marianne+E%3BWilliams%2C+Amy+M%3BRobertson%2C+McKaylee%3BHorney%2C+Jennifer%3BHsia%2C+Jason&rft.aulast=Zotti&rft.aufirst=Marianne&rft.date=2013-07-01&rft.volume=17&rft.issue=5&rft.spage=783&rft.isbn=&rft.btitle=&rft.title=Maternal+and+child+health+journal&rft.issn=1573-6628&rft_id=info:doi/10.1007%2Fs10995-012-1068-x LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2014-01-13 N1 - Date created - 2013-06-10 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Birth. 2006 Jun;33(2):91-3 [16732772] Matern Child Health J. 2007 Jul;11(4):307-11 [17253147] Hum Reprod. 2007 Nov;22(11):3013-20 [17905748] Matern Child Health J. 1998 Sep;2(3):145-54 [10728271] Am J Obstet Gynecol. 2001 Mar;184(4):637-42 [11262465] J Fam Psychol. 2002 Mar;16(1):14-25 [11915406] MMWR Morb Mortal Wkly Rep. 2002 Jul 12;51(27):589-92 [12139201] JAMA. 2003 Aug 6;290(5):595-6 [12902358] Am J Public Health. 1980 Sep;70(9):964-73 [7406096] Public Health Rep. 1981 Jul-Aug;96(4):350-6 [7255659] Vital Health Stat 4. 1991 Jun;(28):1-34 [1713727] Epidemiology. 1992 Jan;3(1):17-22 [1554805] Environ Health Perspect. 1993 Jul;101 Suppl 2:131-6 [8243383] Environ Health Perspect. 2004 Dec;112(17):1772-8 [15579426] Adv Data. 2004 Dec 10;(350):1-36 [15633582] Obstet Gynecol. 2005 May;105(5 Pt 1):1084-91 [15863548] Mt Sinai J Med. 2008 Mar-Apr;75(2):129-34 [18500713] Am J Med Sci. 2008 Aug;336(2):111-5 [18703903] NCHS Data Brief. 2009 Apr;(16):1-8 [19389328] Lancet. 2009 Aug 8;374(9688):451-8 [19643469] Natl Vital Stat Rep. 2009 Aug 28;58(2):1-28, 32 [19754006] Natl Vital Stat Rep. 2009 Oct 14;58(4):1-14 [20121003] Food Chem Toxicol. 2010 Oct;48(10):2549-76 [20558227] Obstet Gynecol. 2010 Oct;116(4):917-25 [20859156] Risk Anal. 2010 Oct;30(10):1590-601 [20626684] Obstet Gynecol Surv. 2010 Nov;65(11):713-28 [21375788] Matern Child Health J. 2011 Apr;15(3):281-8 [20204482] J Womens Health (Larchmt). 2011 May;20(5):649-51 [21438700] Womens Health Issues. 2012 May-Jun;22(3):e253-7 [22365134] Disaster Med Public Health Prep. 2010 Sep;4 Suppl 1:S39-45 [23105034] Environ Health Perspect. 2005 Aug;113(8):1062-7 [16079080] Neurotoxicology. 2005 Aug;26(4):483-9 [16112316] Neurotoxicology. 2005 Aug;26(4):573-87 [16112323] Paediatr Perinat Epidemiol. 2005 Sep;19(5):334-41 [16115284] Obstet Gynecol. 2005 Dec;106(6):1469-70 [16319282] Demography. 2005 Nov;42(4):675-92 [16463916] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1007/s10995-012-1068-x ER - TY - JOUR T1 - Chemical characterization of domestic oral tobacco products: total nicotine, pH, unprotonated nicotine and tobacco-specific N-nitrosamines. AN - 1353985992; 23517910 AB - In the United States, moist snuff has been studied more widely than other distinct categories of oral tobacco. In this study, we measured pH, moisture, nicotine (total and unprotonated), and tobacco-specific N-nitrosamines (TSNAs) for other established (twist, loose leaf, plug, and dry snuff without pouch) and emerging oral tobacco products (dry snuff pouch, US-made snus, and dissolvable tobacco). Among the seven product categories, product pH ranged from 4.7 to 7.9, and total nicotine concentration spanned from 3.9 to 40.1 mg/g. The most readily absorbable form of nicotine (unprotonated nicotine) varied more than 350-fold, ranging from 0.01 to 3.7 mg/g. While the highest total nicotine concentrations were observed in twist products, snus and dissolvable tobacco had the highest unprotonated nicotine levels. Among all products, total TSNA concentrations ranged from 313 to 76,500 ng/g with dry snuff having the highest total TSNA concentrations. This study demonstrates the diversity among oral tobacco products and highlights the potential of these products to deliver a wide range of nicotine and carcinogenic TSNAs. Characterizing the chemical content of these products may be helpful in further understanding the risk of marketing these products to oral tobacco users and smokers as an alternative and discrete form of tobacco. Published by Elsevier Ltd. JF - Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association AU - Lawler, Tameka S AU - Stanfill, Stephen B AU - Zhang, Liqin AU - Ashley, David L AU - Watson, Clifford H AD - Centers for Disease Control and Prevention, National Center for Environmental Health, Division of Laboratory Sciences, Tobacco and Volatiles Branch, Atlanta, GA 30341, USA. tlawler@cdc.gov. Y1 - 2013/07// PY - 2013 DA - July 2013 SP - 380 EP - 386 VL - 57 KW - Nitrosamines KW - 0 KW - Nicotine KW - 6M3C89ZY6R KW - Index Medicus KW - United States KW - Hydrogen-Ion Concentration KW - Nicotine -- analysis KW - Nitrosamines -- analysis KW - Tobacco, Smokeless -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1353985992?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Food+and+chemical+toxicology+%3A+an+international+journal+published+for+the+British+Industrial+Biological+Research+Association&rft.atitle=Chemical+characterization+of+domestic+oral+tobacco+products%3A+total+nicotine%2C+pH%2C+unprotonated+nicotine+and+tobacco-specific+N-nitrosamines.&rft.au=Lawler%2C+Tameka+S%3BStanfill%2C+Stephen+B%3BZhang%2C+Liqin%3BAshley%2C+David+L%3BWatson%2C+Clifford+H&rft.aulast=Lawler&rft.aufirst=Tameka&rft.date=2013-07-01&rft.volume=57&rft.issue=&rft.spage=380&rft.isbn=&rft.btitle=&rft.title=Food+and+chemical+toxicology+%3A+an+international+journal+published+for+the+British+Industrial+Biological+Research+Association&rft.issn=1873-6351&rft_id=info:doi/10.1016%2Fj.fct.2013.03.011 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2014-01-24 N1 - Date created - 2013-05-21 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.fct.2013.03.011 ER - TY - JOUR T1 - The prevalence of selected potentially hazardous workplace exposures in the US: Findings from the 2010 National Health Interview Survey AN - 1560138267; 19416446 AB - Objective Assess the national prevalence of current workplace exposure to potential skin hazards, secondhand smoke (SHS), and outdoor work among various industry and occupation groups. Also, assess the national prevalence of chronic workplace exposure to vapors, gas, dust, and fumes (VGDF) among these groups. Methods Data were obtained from the 2010 National Health Interview Survey (NHIS). NHIS is a multistage probability sample survey of the civilian non-institutionalized population of the US. Prevalence rates and their variances were calculated using SUDAAN to account for the complex NHIS sample design. Results The data for 2010 were available for 17,524 adults who worked in the 12 months that preceded interview. The highest prevalence rates of hazardous workplace exposures were typically in agriculture, mining, and construction. The prevalence rate of frequent handling of or skin contact with chemicals, and of non-smokers frequently exposed to SHS at work was highest in mining and construction. Outdoor work was most common in agriculture (85%), construction (73%), and mining (65%). Finally, frequent occupational exposure to VGDF was most common among mining (67%), agriculture (53%), and construction workers (51%). Conclusion We identified industries and occupations with the highest prevalence of potentially hazardous workplace exposures, and provided targets for investigation and intervention activities. Am. J. Ind. Med. 56:635-646, 2013. copyright 2012 Wiley Periodicals, Inc. JF - American Journal of Industrial Medicine AU - Calvert, Geoffrey M AU - Luckhaupt, Sara E AU - Sussell, Aaron AU - Dahlhamer, James M AU - Ward, Brian W AD - Division of Health Interview Statistics, National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, Maryland., gcalvert@cdc.gov Y1 - 2013/06// PY - 2013 DA - Jun 2013 SP - 635 EP - 646 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 56 IS - 6 SN - 0271-3586, 0271-3586 KW - Toxicology Abstracts; Health & Safety Science Abstracts KW - occupational exposure KW - industry KW - occupations KW - dermatitis KW - tobacco smoke pollution KW - heat stress disorders KW - Chemicals KW - Agriculture KW - Data processing KW - Skin KW - Fumes KW - Intervention KW - Dust KW - Smoke KW - Vapors KW - Passive smoking KW - Mining KW - Construction industry KW - Occupational exposure KW - H 1000:Occupational Safety and Health KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1560138267?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=The+prevalence+of+selected+potentially+hazardous+workplace+exposures+in+the+US%3A+Findings+from+the+2010+National+Health+Interview+Survey&rft.au=Calvert%2C+Geoffrey+M%3BLuckhaupt%2C+Sara+E%3BSussell%2C+Aaron%3BDahlhamer%2C+James+M%3BWard%2C+Brian+W&rft.aulast=Calvert&rft.aufirst=Geoffrey&rft.date=2013-06-01&rft.volume=56&rft.issue=6&rft.spage=635&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=02713586&rft_id=info:doi/10.1002%2Fajim.22089 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Last updated - 2015-03-04 N1 - SubjectsTermNotLitGenreText - Smoke; Agriculture; Vapors; Fumes; Skin; Data processing; Dust; Occupational exposure; Chemicals; Passive smoking; Intervention; Mining; Construction industry DO - http://dx.doi.org/10.1002/ajim.22089 ER - TY - JOUR T1 - Fatal occupational injuries among U.S. law enforcement officers: A comparison of national surveillance systems AN - 1560138208; 19416438 AB - Background This study describes and compares the three surveillance systems used to record occupational injury fatalities among U.S. law enforcement officers (LEOs). Methods The Census of Fatal Occupational Injuries (CFOI), National Law Enforcement Officer Memorial Fund database (NLEOMF), and Law Enforcement Officers Killed and Assaulted reports (LEOKA) were examined for LEO deaths between 2003 and 2009. Fatality rates per 100,000 workers were calculated and compared. Results Between 2003 and 2009, the NLEOMF reported 1,050 fatalities (rate of 16.4 per 100,000 workers), the CFOI reported 968 fatalities (15.1 per 100,000), and the LEOKA recorded 853 fatalities (13.3 per 100,000). The LEOKA under-counted the number of fatalities compared to the NLEOMF and CFOI. Discrepancies were found between the LEOKA, NLEOMF, and CFOI regarding age, race, and Hispanic origin. Similar patterns for cause of fatality were found; however, the NLEOMF recorded a higher number of "other" fatalities compared to the other two systems. Conclusions This study fills a critical knowledge gap by providing an overview of the three surveillance systems used to enumerate LEO occupational deaths. Understanding the differences across the systems is critical when utilizing them for surveillance research. Am. J. Ind. Med. 56:693-700, 2013. copyright 2013 Wiley Periodicals, Inc. JF - American Journal of Industrial Medicine AU - Tiesman, Hope M AU - Swedler, David I AU - Konda, Srinivas AU - Pollack, Keshia M AD - Department of Health Policy and Management, Education and Research Center for Occupational Safety and Health, Center for Injury Research and Policy, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland., htiesman@cdc.gov Y1 - 2013/06// PY - 2013 DA - Jun 2013 SP - 693 EP - 700 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 56 IS - 6 SN - 0271-3586, 0271-3586 KW - Toxicology Abstracts; Health & Safety Science Abstracts KW - fatality rates KW - occupation KW - police KW - surveillance KW - traumatic injury KW - Mortality KW - Funds KW - Age KW - Law enforcement KW - Injuries KW - Occupational safety KW - Workers KW - Databases KW - Reviews KW - Census KW - Ethnic groups KW - Races KW - H 1000:Occupational Safety and Health KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1560138208?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Fatal+occupational+injuries+among+U.S.+law+enforcement+officers%3A+A+comparison+of+national+surveillance+systems&rft.au=Tiesman%2C+Hope+M%3BSwedler%2C+David+I%3BKonda%2C+Srinivas%3BPollack%2C+Keshia+M&rft.aulast=Tiesman&rft.aufirst=Hope&rft.date=2013-06-01&rft.volume=56&rft.issue=6&rft.spage=693&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=02713586&rft_id=info:doi/10.1002%2Fajim.22182 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Last updated - 2015-03-04 N1 - SubjectsTermNotLitGenreText - Databases; Workers; Age; Injuries; Reviews; Census; Races; Mortality; Funds; Law enforcement; Occupational safety; Ethnic groups DO - http://dx.doi.org/10.1002/ajim.22182 ER - TY - JOUR T1 - Job insecurity, work-family imbalance, and hostile work environment: Prevalence data from the 2010 National Health Interview Survey AN - 1560138188; 19416441 AB - Background Little nationally representative information on job insecurity, work-family imbalance, and hostile work environments experienced by workers in the US is available. Methods Prevalence rates from the 2010 National Health Interview Survey (NHIS) were calculated for three workplace psychosocial factors (job insecurity, work-family imbalance, bullying/harassment) using SUDAAN to account for the complex NHIS sample design. Results Data were available for 17,524 adults who worked in the 12 months that preceded the interview. Overall prevalence rates were 31.7% for job insecurity, 16.3% for work-family imbalance, and 7.8% for hostile work environment (being bullied or harassed). The highest prevalence rate of job insecurity was found for construction and extraction occupations. Workers in legal occupations had the highest prevalence rate of work-family imbalance. Workers in protective service occupations had the highest prevalence rate of hostile work environment. Conclusions We identified demographic characteristics along with industries and occupations with the highest prevalence rates for three adverse workplace psychosocial factors. These data can be used for benchmarking and identification of targets for investigation and intervention activities. Am. J. Ind. Med. 56:660-669, 2013. copyright 2012 Wiley Periodicals, Inc. JF - American Journal of Industrial Medicine AU - Alterman, Toni AU - Luckhaupt, Sara E AU - Dahlhamer, James M AU - Ward, Brian W AU - Calvert, Geoffrey M AD - Division of Health Interview Statistics, National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, Maryland., talterman@cdc.gov Y1 - 2013/06// PY - 2013 DA - Jun 2013 SP - 660 EP - 669 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 56 IS - 6 SN - 0271-3586, 0271-3586 KW - Health & Safety Science Abstracts KW - job stress KW - national survey KW - bullying KW - job insecurity KW - work-family imbalance KW - Demography KW - Intervention KW - Bullying KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1560138188?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Job+insecurity%2C+work-family+imbalance%2C+and+hostile+work+environment%3A+Prevalence+data+from+the+2010+National+Health+Interview+Survey&rft.au=Alterman%2C+Toni%3BLuckhaupt%2C+Sara+E%3BDahlhamer%2C+James+M%3BWard%2C+Brian+W%3BCalvert%2C+Geoffrey+M&rft.aulast=Alterman&rft.aufirst=Toni&rft.date=2013-06-01&rft.volume=56&rft.issue=6&rft.spage=660&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=02713586&rft_id=info:doi/10.1002%2Fajim.22123 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Last updated - 2014-10-02 N1 - SubjectsTermNotLitGenreText - Demography; Intervention; Bullying DO - http://dx.doi.org/10.1002/ajim.22123 ER - TY - JOUR T1 - Prevalence and work-relatedness of carpal tunnel syndrome in the working population, United States, 2010 national health interview survey AN - 1560137312; 19416449 AB - Background Patterns of prevalence and work-relatedness of carpal tunnel syndrome (CTS) among workers offer clues about risk factors and targets for prevention. Methods Data from an occupational health supplement to the 2010 National Health Interview Survey were used to estimate the prevalence of self-reported clinician-diagnosed CTS overall and by demographic characteristics. The proportion of these cases self-reported to have been attributed to work by clinicians was also examined overall and by demographic characteristics. In addition, the distribution of industry and occupation (I&O) categories to which work-related cases of CTS were attributed was compared to the distribution of I&O categories of employment among current/recent workers. Results Data were available for 27,157 adults, including 17,524 current/recent workers. The overall lifetime prevalence of clinician-diagnosed CTS among current/recent workers was 6.7%. The 12-month prevalence was 3.1%, representing approximately 4.8 million workers with current CTS; 67.1% of these cases were attributed to work by clinicians, with overrepresentation of certain I&O categories. Conclusions CTS affected almost 5 million U.S. workers in 2010, with prevalence varying by demographic characteristics and I&O. Am. J. Ind. Med. 56:615-624, 2013. copyright 2012 Wiley Periodicals, Inc. JF - American Journal of Industrial Medicine AU - Luckhaupt, Sara E AU - Dahlhamer, James M AU - Ward, Brian W AU - Sweeney, Marie H AU - Sestito, John P AU - Calvert, Geoffrey M AD - Divison of Health Interview Statistics, National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, Maryland., sluckhaupt@cdc.gov Y1 - 2013/06// PY - 2013 DA - Jun 2013 SP - 615 EP - 624 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 56 IS - 6 SN - 0271-3586, 0271-3586 KW - Risk Abstracts; Health & Safety Science Abstracts KW - industry KW - occupations KW - carpal tunnel syndrome KW - occupational diseases KW - Demography KW - USA KW - Prevention KW - Overuse injuries KW - Carpal tunnel syndrome KW - Risk factors KW - Employment KW - Occupational health KW - R2 23080:Industrial and labor KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1560137312?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Prevalence+and+work-relatedness+of+carpal+tunnel+syndrome+in+the+working+population%2C+United+States%2C+2010+national+health+interview+survey&rft.au=Luckhaupt%2C+Sara+E%3BDahlhamer%2C+James+M%3BWard%2C+Brian+W%3BSweeney%2C+Marie+H%3BSestito%2C+John+P%3BCalvert%2C+Geoffrey+M&rft.aulast=Luckhaupt&rft.aufirst=Sara&rft.date=2013-06-01&rft.volume=56&rft.issue=6&rft.spage=615&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=02713586&rft_id=info:doi/10.1002%2Fajim.22048 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Last updated - 2014-10-02 N1 - SubjectsTermNotLitGenreText - Demography; Prevention; Overuse injuries; Risk factors; Carpal tunnel syndrome; Employment; Occupational health; USA DO - http://dx.doi.org/10.1002/ajim.22048 ER - TY - JOUR T1 - Prevalence rates of work organization characteristics among workers in the U.S.: Data from the 2010 National Health Interview Survey AN - 1560137098; 19416445 AB - Background Surveillance is needed to capture work organization characteristics and to identify their trends. Methods Data from the 2010 National Health Interview Survey (NHIS) were used to calculate prevalence rates for four work organization characteristics (long work hours, non-standard work arrangements, temporary positions, and alternative shifts) overall, and by demographic characteristics, and industry and occupation of current/recent employment. Results Data were available for 27,157 adults, of which 65% were current/recent workers. Among adults who worked in the past 12 months, 18.7% worked 48hr or more per week, 7.2% worked 60hr or more per week, 18.7% had non-standard work arrangements, 7.2% were in temporary positions, and 28.7% worked an alternative shift. Conclusions Prevalence rates of work organization characteristics are provided. These national estimates can be used to help occupational health professionals and employers to identify emerging occupational safety and health risks, allow researchers to examine associations with health, and use the data for benchmarking. Am. J. Ind. Med. 56:647-659, 2013. copyright 2012 Wiley Periodicals, Inc. JF - American Journal of Industrial Medicine AU - Alterman, Toni AU - Luckhaupt, Sara E AU - Dahlhamer, James M AU - Ward, Brian W AU - Calvert, Geoffrey M AD - Division of Health Interview Statistics, National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, Maryland., talterman@cdc.gov Y1 - 2013/06// PY - 2013 DA - Jun 2013 SP - 647 EP - 659 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 56 IS - 6 SN - 0271-3586, 0271-3586 KW - Risk Abstracts; Health & Safety Science Abstracts KW - work organization KW - job stress KW - surveillance KW - occupational health KW - national survey KW - long work hours KW - non-standard work arrangements KW - temporary work KW - shift work KW - Demography KW - Health risks KW - Occupational safety KW - Employment KW - Working conditions KW - Occupational health KW - R2 23080:Industrial and labor KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1560137098?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Prevalence+rates+of+work+organization+characteristics+among+workers+in+the+U.S.%3A+Data+from+the+2010+National+Health+Interview+Survey&rft.au=Alterman%2C+Toni%3BLuckhaupt%2C+Sara+E%3BDahlhamer%2C+James+M%3BWard%2C+Brian+W%3BCalvert%2C+Geoffrey+M&rft.aulast=Alterman&rft.aufirst=Toni&rft.date=2013-06-01&rft.volume=56&rft.issue=6&rft.spage=647&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=02713586&rft_id=info:doi/10.1002%2Fajim.22108 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Last updated - 2014-10-02 N1 - SubjectsTermNotLitGenreText - Demography; Health risks; Occupational safety; Employment; Working conditions; Occupational health DO - http://dx.doi.org/10.1002/ajim.22108 ER - TY - JOUR T1 - The silent threat: asymptomatic parasitemia and malaria transmission AN - 1448223987; 18678370 AB - Scale-up of malaria control interventions has resulted in a substantial decline in global malaria morbidity and mortality. Despite this achievement, there is evidence that current interventions alone will not lead to malaria elimination in most malaria-endemic areas and additional strategies need to be considered. Use of antimalarial drugs to target the reservoir of malaria infection is an option to reduce the transmission of malaria between humans and mosquito vectors. However, a large proportion of human malaria infections are asymptomatic, requiring treatment that is not triggered by care-seeking for clinical illness. This article reviews the evidence that asymptomatic malaria infection plays an important role in malaria transmission and that interventions to target this parasite reservoir may be needed to achieve malaria elimination in both low- and high-transmission areas. JF - Expert Review of Anti-infective Therapy AU - Lindblade, Kim A AU - Steinhardt, Laura AU - Samuels, Aaron AU - Kachur, S Patrick AU - Slutsker, Laurence AD - Malaria Branch, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, 1600 Clifton Rd. NE, MS A-06, Atlanta, GA 30333, USA, kil2@cdc.gov Y1 - 2013/06// PY - 2013 DA - June 2013 SP - 623 EP - 639 PB - Future Science Group (FSG), Unitec House, 2 Albert Place London N3 1QB United Kingdom VL - 11 IS - 6 SN - 1478-7210, 1478-7210 KW - ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - antimalarial KW - asymptomatic KW - elimination KW - infection KW - interventions KW - malaria KW - parasite KW - Mortality KW - Reservoir KW - Parasites KW - Human diseases KW - Disease control KW - Vectors KW - Malaria KW - Pest control KW - Hosts KW - Infection KW - Morbidity KW - Disease transmission KW - Public health KW - parasitemia KW - Reviews KW - Drugs KW - Mortality causes KW - K 03400:Human Diseases KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1448223987?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Expert+Review+of+Anti-infective+Therapy&rft.atitle=The+silent+threat%3A+asymptomatic+parasitemia+and+malaria+transmission&rft.au=Lindblade%2C+Kim+A%3BSteinhardt%2C+Laura%3BSamuels%2C+Aaron%3BKachur%2C+S+Patrick%3BSlutsker%2C+Laurence&rft.aulast=Lindblade&rft.aufirst=Kim&rft.date=2013-06-01&rft.volume=11&rft.issue=6&rft.spage=623&rft.isbn=&rft.btitle=&rft.title=Expert+Review+of+Anti-infective+Therapy&rft.issn=14787210&rft_id=info:doi/10.1586%2Feri.13.45 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-10-01 N1 - Number of references - 132 N1 - Last updated - 2016-09-29 N1 - SubjectsTermNotLitGenreText - Parasites; Reservoir; Human diseases; Disease control; Pest control; Malaria; Hosts; Mortality causes; Public health; Mortality; parasitemia; Reviews; Vectors; Infection; Drugs; Morbidity; Disease transmission DO - http://dx.doi.org/10.1586/eri.13.45 ER - TY - JOUR T1 - Nationwide outbreak of Salmonella Montevideo infections associated with contaminated imported black and red pepper: warehouse membership cards provide critical clues to identify the source AN - 1399915432; 18144564 AB - In November 2009, we initiated a multistate investigation of Salmonella Montevideo infections with pulsed-field gel electrophoresis pattern JIXX01.0011. We identified 272 cases in 44 states with illness onset dates ranging from 1 July 2009 to 14 April 2010. To help generate hypotheses, warehouse store membership card information was collected to identify products consumed by cases. These records identified 19 ill persons who purchased company A salami products before onset of illness. A case-control study was conducted. Ready-to-eat salami consumption was significantly associated with illness (matched odds ratio 8.5, 95% confidence interval 2.1-75.9). The outbreak strain was isolated from company A salami products from an environmental sample from one manufacturing plant, and sealed containers of black and red pepper at the facility. This outbreak illustrates the importance of using membership card information to assist in identifying suspect vehicles, the potential for spices to contaminate ready-to-eat products, and preventing raw ingredient contamination of these products. JF - Epidemiology and Infection AU - GIERALTOWSKI, L AU - Julian, E AU - Pringle, J AU - MacDonald, K AU - Quilliam, D AU - Marsden-Haug, N AU - Saathoff-Huber, L AU - Von Stein, D AU - Kissler, B AU - Parish, M AU - Elder, D AU - Howard-King, V AU - Besser, J AU - Sodha, S AU - LOHARIKAR, A AU - Dalton, S AU - Williams, I AU - BEHRAVESH, CBARTON AD - Epidemic Intelligence Service assigned to the Division of Foodborne, Waterborne and Environmental Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA, lax2@cdc.gov Y1 - 2013/06// PY - 2013 DA - Jun 2013 SP - 1244 EP - 1252 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 141 IS - 6 SN - 0950-2688, 0950-2688 KW - Health & Safety Science Abstracts; Microbiology Abstracts B: Bacteriology KW - Containers KW - Salami KW - Uruguay, Montevideo KW - Outbreaks KW - Salmonella KW - H 12000:Epidemiology and Public Health KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1399915432?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Nationwide+outbreak+of+Salmonella+Montevideo+infections+associated+with+contaminated+imported+black+and+red+pepper%3A+warehouse+membership+cards+provide+critical+clues+to+identify+the+source&rft.au=GIERALTOWSKI%2C+L%3BJulian%2C+E%3BPringle%2C+J%3BMacDonald%2C+K%3BQuilliam%2C+D%3BMarsden-Haug%2C+N%3BSaathoff-Huber%2C+L%3BVon+Stein%2C+D%3BKissler%2C+B%3BParish%2C+M%3BElder%2C+D%3BHoward-King%2C+V%3BBesser%2C+J%3BSodha%2C+S%3BLOHARIKAR%2C+A%3BDalton%2C+S%3BWilliams%2C+I%3BBEHRAVESH%2C+CBARTON&rft.aulast=GIERALTOWSKI&rft.aufirst=L&rft.date=2013-06-01&rft.volume=141&rft.issue=6&rft.spage=1244&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268812001859 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-07-01 N1 - Number of references - 1 N1 - Last updated - 2014-03-10 N1 - SubjectsTermNotLitGenreText - Salami; Outbreaks; Salmonella; Uruguay, Montevideo DO - http://dx.doi.org/10.1017/S0950268812001859 ER - TY - JOUR T1 - Associations Between Partner-Venue Specific Personal Responsibility Beliefs and Transmission Risk Behavior by HIV-Positive Men Who Have Sex with Men (MSM) AN - 1367493406; 18090577 AB - Personal responsibility beliefs of HIV-positive individuals to protect sex partners are an important determinant of engagement in transmission risk behavior. However, the degree to which such beliefs vary across different partners is unknown. HIV-positive men who have sex with men (n = 248) completing an online survey rated their personal responsibility beliefs for partners met in up to four different ways: (a) in a bar; (b) through the internet; (c) in a public sex environment (PSE); or (d) through friends or family. For those reporting two or more partner-meeting venues in the prior 3 months (n = 98), about a third reported variation in responsibility ratings. Means among the venues were compared in pairwise fashion, with the strongest beliefs accruing to partners met through friends or family and the least with partners met in PSEs. These results provide further evidence that identifying ways to increase personal responsibility beliefs is an important goal, as well as is the application of Bandura's theory of moral agency to HIV transmission risk behavior. JF - AIDS and Behavior AU - O'Leary, Ann AU - Horvath, Keith J AU - Simon Rosser, BR AD - Prevention Research Branch, Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, NCHHSTP, 1600 Clifton Road, MSE-37, Atlanta, GA, 30333, USA, aoleary@cdc.gov Y1 - 2013/06// PY - 2013 DA - Jun 2013 SP - 1855 EP - 1861 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 17 IS - 5 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Risk Abstracts KW - Acquired immune deficiency syndrome KW - Human immunodeficiency virus KW - Responsibility KW - Sex KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1367493406?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Associations+Between+Partner-Venue+Specific+Personal+Responsibility+Beliefs+and+Transmission+Risk+Behavior+by+HIV-Positive+Men+Who+Have+Sex+with+Men+%28MSM%29&rft.au=O%27Leary%2C+Ann%3BHorvath%2C+Keith+J%3BSimon+Rosser%2C+BR&rft.aulast=O%27Leary&rft.aufirst=Ann&rft.date=2013-06-01&rft.volume=17&rft.issue=5&rft.spage=1855&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-012-0291-1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-06-01 N1 - Number of references - 1 N1 - Last updated - 2014-03-10 N1 - SubjectsTermNotLitGenreText - Sex; Responsibility; Human immunodeficiency virus DO - http://dx.doi.org/10.1007/s10461-012-0291-1 ER - TY - JOUR T1 - HIV/AIDS Prevention, Faith, and Spirituality among Black/African American and Latino Communities in the United States: Strengthening Scientific Faith-Based Efforts to Shift the Course of the Epidemic and Reduce HIV-Related Health Disparities AN - 1352289367; 17935124 AB - Black/African American and Latino communities are disproportionately affected by the domestic HIV/AIDS epidemic. Blacks/African Americans and Latinos are also more likely to report a formal, religious, or faith affiliation when compared with non-Hispanic whites. As such, faith leaders and their institutions have been identified in the National HIV/AIDS Strategy as having a vital role to serve in reducing: (1) HIV-related health disparities and (2) the number of new HIV infections by promoting non-judgmental support for persons living with and at risk for HIV/AIDS and by serving as trusted information resources for their congregants and communities. We describe faith doctrines and faith-science partnerships that are increasing in support of faith-based HIV prevention and service delivery activities and discuss the vital role of these faith-based efforts in highly affected black/African American and Latino communities. JF - Journal of Religion and Health AU - Sutton, Madeline Y AU - Parks, Carolyn P AD - Division of HIV/AIDS Prevention, National Centers for HIV, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Rd NE MS E-45, Atlanta, GA, 30333, USA, msutton@cdc.gov Y1 - 2013/06// PY - 2013 DA - Jun 2013 SP - 514 EP - 530 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 52 IS - 2 SN - 0022-4197, 0022-4197 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - USA KW - Prevention KW - Acquired immune deficiency syndrome KW - Epidemics KW - Human immunodeficiency virus KW - Infection KW - Ethnic groups KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1352289367?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Religion+and+Health&rft.atitle=HIV%2FAIDS+Prevention%2C+Faith%2C+and+Spirituality+among+Black%2FAfrican+American+and+Latino+Communities+in+the+United+States%3A+Strengthening+Scientific+Faith-Based+Efforts+to+Shift+the+Course+of+the+Epidemic+and+Reduce+HIV-Related+Health+Disparities&rft.au=Sutton%2C+Madeline+Y%3BParks%2C+Carolyn+P&rft.aulast=Sutton&rft.aufirst=Madeline&rft.date=2013-06-01&rft.volume=52&rft.issue=2&rft.spage=514&rft.isbn=&rft.btitle=&rft.title=Journal+of+Religion+and+Health&rft.issn=00224197&rft_id=info:doi/10.1007%2Fs10943-011-9499-z LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-05-01 N1 - Number of references - 77 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Acquired immune deficiency syndrome; Epidemics; Infection; Prevention; Human immunodeficiency virus; Ethnic groups; USA DO - http://dx.doi.org/10.1007/s10943-011-9499-z ER - TY - JOUR T1 - Induction of miR-21 -PDCD4 Signaling by Tungsten Carbide-Cobalt Nanoparticles in JB6 Cells Involves ROS-Mediated MAPK Pathways AN - 1458537807; 18782082 AB - Tungsten carbide-cobalt (WC-Co) nanoparticle composites have wide applications because of their hardness and toughness. WC-Co was classified as "probably carcinogenic" to humans by the International Agency for Research on Cancer (IARC) in 2003. It is believed that the toxicity and carcinogenesis of WC-Co is associated with particle size. Recent studies demonstrated that the tumor suppressor gene programmed cell death 4 (PDCD4) and its upstream regulator miR-21 have been considered as oncogenes for novel cancer prevention or anticancer therapies. The present study examined the effects of WC-Co nanoparticles on miR-21-PDCD4 signaling in a mouse epidermal cell line (JB6 P(+)). The results showed that (i) exposure of JB6 cells to WC-Co stimulated a increase of miR-21 generation; (ii) WC-Co also caused inhibition of PDCD4, a tumor suppressor protein and downstream target of miR-21, expression in JB6 cells; (iii) inhibition of ERKs with ERK inhibitor U0126 significantly reversed WC-Co-induced PDCD4 inhibition, but inhibition of p38 with p38 inhibitor SB203580 did not; and (iv) ROS scavengers, N-acetyl-L-cysteine and catalase, blocked the inhibitory effect of WC-Co on PDCD4 expression, while superoxide dismutase promoted the inhibitory effect. These findings demonstrate that WC-Co nanoparticles induce miR-21 generation, but inhibit PDCD4 production, which may be mediated through ROS, especially endogenous H(2)O(2), and ERK pathways. Unraveling the complex mechanisms associated with these events may provide insights into the initiation and progression of WC-Co-induced carcinogenesis. JF - Journal of Environmental Pathology, Toxicology and Oncology AU - Hou, Lichao AU - Bowman, Linda AU - Meighan, Terence G AU - Shi, Xianglin AU - Ding, Min AD - Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, KY 40503, mid5@cdc.gov Y1 - 2013/05/30/ PY - 2013 DA - 2013 May 30 SP - 41 EP - 51 PB - Begell House Inc., 79 Madison Avenue, Suite 1201 New York NY 10016-7892 United States VL - 32 IS - 1 SN - 0731-8898, 0731-8898 KW - Toxicology Abstracts KW - Particle size KW - Tumor suppressor genes KW - MAP kinase KW - Apoptosis KW - Toxicity KW - Catalase KW - Cancer KW - Tungsten KW - Extracellular signal-regulated kinase KW - Oncogenes KW - N-Acetyl-L-cysteine KW - Reactive oxygen species KW - Superoxide dismutase KW - Carcinogenesis KW - nanoparticles KW - Signal transduction KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1458537807?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+Pathology%2C+Toxicology+and+Oncology&rft.atitle=Induction+of+miR-21+-PDCD4+Signaling+by+Tungsten+Carbide-Cobalt+Nanoparticles+in+JB6+Cells+Involves+ROS-Mediated+MAPK+Pathways&rft.au=Hou%2C+Lichao%3BBowman%2C+Linda%3BMeighan%2C+Terence+G%3BShi%2C+Xianglin%3BDing%2C+Min&rft.aulast=Hou&rft.aufirst=Lichao&rft.date=2013-05-30&rft.volume=32&rft.issue=1&rft.spage=41&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+Pathology%2C+Toxicology+and+Oncology&rft.issn=07318898&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-11-01 N1 - Number of references - 33 N1 - Last updated - 2014-05-29 N1 - SubjectsTermNotLitGenreText - Particle size; Tumor suppressor genes; MAP kinase; Apoptosis; Toxicity; Cancer; Catalase; Tungsten; Extracellular signal-regulated kinase; N-Acetyl-L-cysteine; Oncogenes; Reactive oxygen species; Superoxide dismutase; Carcinogenesis; nanoparticles; Signal transduction ER - TY - JOUR T1 - Forecasting invasive pneumococcal disease trends after the introduction of 13-valent pneumococcal conjugate vaccine in the United States, 2010-2020 AN - 1443367316; 18663101 AB - Introduction: Pneumococcal vaccines are highly effective at preventing invasive pneumococcal disease (IPD), a leading cause of global morbidity. Because pneumococcal vaccines can be expensive, it is useful to estimate what impact might be expected from their introduction. Our objective was to develop a statistical model that could predict rates of IPD following introduction of 13-valent pneumococcal conjugate vaccine (PCV13) inthe U.S. Methods: We used active surveillance data to design and validate a Poisson model forecasting the reductions in IPD observed after U.S. introduction of 7-valent pneumococcal conjugate vaccine (PCV7) in 2000. We used this model to forecast rates of IPD from 2010 to 2020 in the presence of PCV13. Because increases in non-PCV7-type IPD were evident following PCV7 introduction, we evaluated varying levels of increase in non-PCV13-type IPD ("serotype replacement") by sensitivity analyses. Results: A total of 43,507 cases of IPD were identified during 1998-2009; cases from this period were used to develop the model, which accurately predicted indirect effects of PCV7 in adults, as well as serotype replacement. Assuming that PCV13 provides similar protection against PCV13 serotypes as PCV7 did against PCV7 serotypes, the base-case model predicted approximately 168,000 cases of IPD prevented from 2011 to 2020. When serotype replacement was varied in sensitivity analyses from 0 to levels comparable to that seen with serotype 19A (the most common replacement serotype since PCV7 was introduced), the model predicted 167,000-170,000 cases prevented. The base-case model predicted rates of IPD in children under five years of age decreasing from 21.9 to 9.3 cases per 100,000 population. Conclusions: This model provides a "benchmark" for assessing progress in the prevention of IPD in the years after PCV13 introduction. The amount of serotype replacement is unlikely to greatly affect the overall number of cases prevented by PCV13. JF - Vaccine AU - Link-Gelles, R AU - Taylor, T AU - Moore, M R AD - Centers for Disease Control and Prevention, 1600 Clifton Road, Mailstop C-25, Atlanta, GA 30333, United States, HZT7@cdc.gov Y1 - 2013/05/24/ PY - 2013 DA - 2013 May 24 SP - 2572 EP - 2577 VL - 31 IS - 22 SN - 0264-410X, 0264-410X KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Age KW - Streptococcus pneumoniae KW - Serotypes KW - J:02400 KW - F:06905 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1443367316?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Forecasting+invasive+pneumococcal+disease+trends+after+the+introduction+of+13-valent+pneumococcal+conjugate+vaccine+in+the+United+States%2C+2010-2020&rft.au=Link-Gelles%2C+R%3BTaylor%2C+T%3BMoore%2C+M+R&rft.aulast=Link-Gelles&rft.aufirst=R&rft.date=2013-05-24&rft.volume=31&rft.issue=22&rft.spage=2572&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-10-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Serotypes; Streptococcus pneumoniae ER - TY - CPAPER T1 - The Laboratory Efficiencies Initiative T2 - 113th General Meeting of the American Society for Microbiology (ASM 2013) AN - 1412153475; 6225931 JF - 113th General Meeting of the American Society for Microbiology (ASM 2013) AU - Ridderhof, John Y1 - 2013/05/18/ PY - 2013 DA - 2013 May 18 KW - Microbiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1412153475?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=113th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2013%29&rft.atitle=The+Laboratory+Efficiencies+Initiative&rft.au=Ridderhof%2C+John&rft.aulast=Ridderhof&rft.aufirst=John&rft.date=2013-05-18&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=113th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2013%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/start.aspx?mkey={15C31F4D-CBA9-43A6-B6E1-2F312E144DB4} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-06-30 N1 - Last updated - 2013-07-25 ER - TY - CPAPER T1 - A Slice of Life: Clinicopathologic and Molecular Tissue-Based Approaches to Pathogen Diagnosis T2 - 113th General Meeting of the American Society for Microbiology (ASM 2013) AN - 1412153259; 6225995 JF - 113th General Meeting of the American Society for Microbiology (ASM 2013) AU - Zaki, Sherif Y1 - 2013/05/18/ PY - 2013 DA - 2013 May 18 KW - Pathogens UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1412153259?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=113th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2013%29&rft.atitle=A+Slice+of+Life%3A+Clinicopathologic+and+Molecular+Tissue-Based+Approaches+to+Pathogen+Diagnosis&rft.au=Zaki%2C+Sherif&rft.aulast=Zaki&rft.aufirst=Sherif&rft.date=2013-05-18&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=113th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2013%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/start.aspx?mkey={15C31F4D-CBA9-43A6-B6E1-2F312E144DB4} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-06-30 N1 - Last updated - 2013-07-25 ER - TY - CPAPER T1 - Laboratory Detection of Antibiotic Resistance - Where are we going? T2 - 113th General Meeting of the American Society for Microbiology (ASM 2013) AN - 1412146698; 6226231 JF - 113th General Meeting of the American Society for Microbiology (ASM 2013) AU - Patel, Jean Y1 - 2013/05/18/ PY - 2013 DA - 2013 May 18 KW - Antibiotic resistance UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1412146698?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=113th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2013%29&rft.atitle=Laboratory+Detection+of+Antibiotic+Resistance+-+Where+are+we+going%3F&rft.au=Patel%2C+Jean&rft.aulast=Patel&rft.aufirst=Jean&rft.date=2013-05-18&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=113th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2013%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/start.aspx?mkey={15C31F4D-CBA9-43A6-B6E1-2F312E144DB4} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-06-30 N1 - Last updated - 2013-07-25 ER - TY - CPAPER T1 - HIV Screening and Surveillance T2 - 113th General Meeting of the American Society for Microbiology (ASM 2013) AN - 1412146646; 6226248 JF - 113th General Meeting of the American Society for Microbiology (ASM 2013) AU - Duffus, Wayne Y1 - 2013/05/18/ PY - 2013 DA - 2013 May 18 KW - Screening KW - Human immunodeficiency virus UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1412146646?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=113th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2013%29&rft.atitle=HIV+Screening+and+Surveillance&rft.au=Duffus%2C+Wayne&rft.aulast=Duffus&rft.aufirst=Wayne&rft.date=2013-05-18&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=113th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2013%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/start.aspx?mkey={15C31F4D-CBA9-43A6-B6E1-2F312E144DB4} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-06-30 N1 - Last updated - 2013-07-25 ER - TY - CPAPER T1 - Diagnosis of Plasmodium knowlesi Infection T2 - 113th General Meeting of the American Society for Microbiology (ASM 2013) AN - 1412146595; 6226097 JF - 113th General Meeting of the American Society for Microbiology (ASM 2013) AU - Barnwell, John Y1 - 2013/05/18/ PY - 2013 DA - 2013 May 18 KW - Infection KW - Plasmodium knowlesi UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1412146595?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=113th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2013%29&rft.atitle=Diagnosis+of+Plasmodium+knowlesi+Infection&rft.au=Barnwell%2C+John&rft.aulast=Barnwell&rft.aufirst=John&rft.date=2013-05-18&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=113th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2013%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/start.aspx?mkey={15C31F4D-CBA9-43A6-B6E1-2F312E144DB4} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-06-30 N1 - Last updated - 2013-07-25 ER - TY - CPAPER T1 - Epidemiology of Gastrointestinal Infections in the United States- A Public Health Perspective T2 - 113th General Meeting of the American Society for Microbiology (ASM 2013) AN - 1412146520; 6226242 JF - 113th General Meeting of the American Society for Microbiology (ASM 2013) AU - Tauxe, Robert Y1 - 2013/05/18/ PY - 2013 DA - 2013 May 18 KW - Epidemiology KW - Infection KW - Public health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1412146520?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=113th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2013%29&rft.atitle=Epidemiology+of+Gastrointestinal+Infections+in+the+United+States-+A+Public+Health+Perspective&rft.au=Tauxe%2C+Robert&rft.aulast=Tauxe&rft.aufirst=Robert&rft.date=2013-05-18&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=113th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2013%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/start.aspx?mkey={15C31F4D-CBA9-43A6-B6E1-2F312E144DB4} LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-06-30 N1 - Last updated - 2013-07-25 ER - TY - JOUR T1 - Ecology of Potential West Nile Virus Vectors m Southeastern Louisiana: Enzootic Transmission in the Relative Absence of Culex quinquefasciatus AN - 1647018040; 21172093 AB - A study of West Nile virus (WNV) ecology was conducted in St. Tammany Parish, Louisiana, from 2002 to 2004. Mosquitoes were collected weekly throughout the year using Centers for Disease Control and Prevention (CDC) light traps placed at 1.5 and 6 m above the ground and gravid traps. A total of 379,466 mosquitoes was collected. WNV was identified in 32 pools of mosquitoes comprising four species; 23 positive pools were from Culex nigripalpus collected during 2003. Significantly more positive pools were obtained from C.x. nigripalpus collected in traps placed at 6 m than 1.5 m that year, but abundance did not differ by trap height. In contrast, C.x. nigripalpus abundance was significantly greater in traps placed at 6 m in 2002 and 2004. Annual temporal variation in C.x. nigripalpus peak seasonal abundance has important implications for WNV transmission in Louisiana. One WNV-positive pool, from C.x. erraticus, was collected during the winter of 2004, showing year-round transmission. The potential roles of additional mosquito species in WNV transmission in southeastern Louisiana are discussed. JF - American Journal of Tropical Medicine and Hygiene AU - Godsey, Marvin S, Jr AU - King, Raymond J AU - Burkhalter, Kristen AU - Delorey, Mark AU - Colton, Leah AU - Charnetzky, Dawn AU - Sutherland, Genevieve AU - Ezenwa, Vanessa O AU - Wilson, Lawrence A AU - Coffey, Michelle AU - Milheim, Lesley E AU - Taylor, Viki G AU - Palmisano, Charles AU - Wesson, Dawn M AU - Guptill, Stephen C AD - Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado; Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia; US Geological Survey, Eastern Geography Science Center, Reston, Virginia; Fernbank Science Center, Atlanta, Georgia; St. Tammany Parish Mosquito Abatement District, Slidell, Louisiana; Department of Tropical Medicine, School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana; Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, 3156 Rampart Road, Fort Collins, CO 80521, mjg9@cdc.gov Y1 - 2013/05// PY - 2013 DA - May 2013 SP - 986 EP - 996 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 88 IS - 5 SN - 0002-9637, 0002-9637 KW - Entomology Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Culex quinquefasciatus KW - Temporal variations KW - Light traps KW - Abundance KW - Disease control KW - Vectors KW - Pest control KW - Hosts KW - Public health KW - Disease transmission KW - Culex nigripalpus KW - USA, Louisiana KW - Hygiene KW - Aquatic insects KW - West Nile virus KW - K 03410:Animal Diseases KW - J 02410:Animal Diseases KW - V 22410:Animal Diseases KW - Z 05340:Ecology and Behavior KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08502:Methods and instruments UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1647018040?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Ecology+of+Potential+West+Nile+Virus+Vectors+m+Southeastern+Louisiana%3A+Enzootic+Transmission+in+the+Relative+Absence+of+Culex+quinquefasciatus&rft.au=Godsey%2C+Marvin+S%2C+Jr%3BKing%2C+Raymond+J%3BBurkhalter%2C+Kristen%3BDelorey%2C+Mark%3BColton%2C+Leah%3BCharnetzky%2C+Dawn%3BSutherland%2C+Genevieve%3BEzenwa%2C+Vanessa+O%3BWilson%2C+Lawrence+A%3BCoffey%2C+Michelle%3BMilheim%2C+Lesley+E%3BTaylor%2C+Viki+G%3BPalmisano%2C+Charles%3BWesson%2C+Dawn+M%3BGuptill%2C+Stephen+C&rft.aulast=Godsey&rft.aufirst=Marvin&rft.date=2013-05-01&rft.volume=88&rft.issue=5&rft.spage=986&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.12-0109 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Temporal variations; Disease control; Pest control; Hosts; Hygiene; Aquatic insects; Disease transmission; Public health; Light traps; Abundance; Vectors; Culex quinquefasciatus; Culex nigripalpus; West Nile virus; USA, Louisiana DO - http://dx.doi.org/10.4269/ajtmh.12-0109 ER - TY - JOUR T1 - Correlates of Bisexual Behaviors Among Men who have Sex with Men in El Salvador AN - 1642614865; 21178839 AB - Bisexual behaviors may increase transmission pathways of HIV and sexually transmitted infections (STIs) from a higher prevalence group to lower prevalence groups in El Salvador. In 2008, men who have sex with men (MSM) were recruited in San Salvador and San Miguel using respondent driven sampling. Participants were interviewed and tested for HIV and STIs. Sixteen seeds and 797 MSM participated; 34.9% in San Salvador and 58.8% in San Miguel reported bisexual behavior. Bisexual behavior was associated with drug use (adjusted odds ratio (AOR) = 2.57, 95% CI: 1.30-5.06) and insertive anal sex (AOR = 5.45, 95% CI: 3.01-9.87), and inversely associated with having a stable male partner (AOR = 0.47, 95% CI: 0.26-0.84) and disclosing MSM behavior to family (AOR = 0.41, 95% CI: 0.22-0.75). Bisexual behavior was associated with risk behaviors with male and female partners that may be associated with HIV and STI transmission. Bisexual men displayed a distinct identity calling for tailored interventions.Original Abstract: En El Salvador las practicas bisexuales pueden aumentar las vias de transmision del VIH e infecciones de transmision sexual (ITS) desde un grupo de mayor prevalencia a grupos de menor prevalencia. En el 2008, se uso el muestreo dirigido por participantes para reclutar a hombres que tienen sexo con hombres (HSH) en San Salvador y San Miguel. Los participantes fueron entrevistados y se les realizaron pruebas de laboratorio para VIH e ITS. Dieciseis semillas y 797 HSH participaron; 34.9% en San Salvador y 58.8% en San Miguel reportaron comportamiento bisexual. El comportamiento bisexual fue asociado con uso de drogas (razon de probabilidades ajustadas (ORA) = 2.57, 95% IC: 1.30-5.06) y sexo anal insertivo (ORA = 5.45, 95% IC: 3.01-9.87), e inversamente asociado con tener una pareja estable masculina (ORA = 0.47, 95% IC: 0.26-0.84), y haber informado a su familia de su preferencia sexual (ORA = 0.41, 95% IC: 0.22-0.75). El comportamiento bisexual fue asociado con comportamientos de riesgo con parejas masculinas y femeninas, lo que puede estar asociado con la transmision del VIH e ITS. Los hombres bisexuales mostraron una identidad distinta y necesitan intervenciones especificas. JF - AIDS and Behavior AU - Kim, Evelyn J AU - Creswell, Jacob AU - Guardado, Maria Elena AU - Shah, Neha AU - Kim, Andrea A AU - Nieto, Ana Isabel AU - Maria Hernandez-Ayala, Flor AU - Monterroso, Edgar AU - Paz-Bailey, Gabriela AD - Division of Global HIV/AIDS, Centers for Disease Control and Prevention, 1600 Clifton Road NE, MS E-30, Atlanta, GA, 30333, USA, ejkim@cdc.gov Y1 - 2013/05// PY - 2013 DA - May 2013 SP - 1279 EP - 1287 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 17 IS - 4 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Risk Abstracts KW - Acquired immune deficiency syndrome KW - Seeds KW - anal sex KW - ASW, Caribbean Sea, Bahamas, San Salvador KW - Intervention KW - Risk taking KW - Homosexuality KW - Anal sex KW - Drug abuse KW - Infection KW - Disease transmission KW - Infectious diseases KW - Behavior KW - Human immunodeficiency virus KW - El Salvador KW - Bisexuality KW - Bisexual KW - Sampling KW - Drugs KW - Sexually transmitted diseases KW - Sex KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1642614865?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Correlates+of+Bisexual+Behaviors+Among+Men+who+have+Sex+with+Men+in+El+Salvador&rft.au=Kim%2C+Evelyn+J%3BCreswell%2C+Jacob%3BGuardado%2C+Maria+Elena%3BShah%2C+Neha%3BKim%2C+Andrea+A%3BNieto%2C+Ana+Isabel%3BMaria+Hernandez-Ayala%2C+Flor%3BMonterroso%2C+Edgar%3BPaz-Bailey%2C+Gabriela&rft.aulast=Kim&rft.aufirst=Evelyn&rft.date=2013-05-01&rft.volume=17&rft.issue=4&rft.spage=1279&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-012-0152-y LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Number of references - 46 N1 - Last updated - 2015-03-04 N1 - SubjectsTermNotLitGenreText - Seeds; anal sex; Bisexual; Sampling; Infection; Drugs; Sex; Disease transmission; Acquired immune deficiency syndrome; Behavior; Infectious diseases; Human immunodeficiency virus; Bisexuality; Risk taking; Intervention; Anal sex; Homosexuality; Drug abuse; Sexually transmitted diseases; El Salvador; ASW, Caribbean Sea, Bahamas, San Salvador DO - http://dx.doi.org/10.1007/s10461-012-0152-y ER - TY - JOUR T1 - Homophobia is Associated with Sexual Behavior that Increases Risk of Acquiring and Transmitting HIV Infection Among Black Men Who Have Sex with Men AN - 1642613465; 21178842 AB - We investigated whether the experience of homophobic events increases the odds of engaging in unprotected anal intercourse (UAI) among black men who have sex with men (MSM) and whether social integration level buffered the association. Participants (N = 1,154) reported homophobic events experienced in the past 12 months. Social integration measures included social support, closeness with family members and friends, attachment to the black gay community, openness about sexuality within religious communities, and MSM social network size. Logistic regression analyses indicated that experiencing homophobia was associated with (1) UAI among men not previously diagnosed with HIV and (2) sexual HIV transmission risk behavior among men who knew they were HIV-infected. None of the social integration measures buffered these associations. Homophobia may promote acquisition and transmission of HIV infection among black MSM. Interventions are needed to reduce homophobia experienced by black MSM. JF - AIDS and Behavior AU - Jeffries, William L AU - Marks, Gary AU - Lauby, Jennifer AU - Murrill, Christopher S AU - Millett, Gregorio A AD - Epidemic Intelligence Service, Division of Applied Sciences, Scientific Education and Professional Development Program Office, Centers for Disease Control and Prevention, 1600 Clifton Road MS E-37, Atlanta, GA, 30333, USA, wjeffries@cdc.gov Y1 - 2013/05// PY - 2013 DA - May 2013 SP - 1442 EP - 1453 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 17 IS - 4 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Risk Abstracts KW - Acquired immune deficiency syndrome KW - Risk taking KW - Intervention KW - Homosexuality KW - Anal sex KW - Infection KW - Sexual behavior KW - Disease transmission KW - Social interactions KW - Sexuality KW - Integration KW - Human immunodeficiency virus KW - Regression analysis KW - Sex KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1642613465?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Homophobia+is+Associated+with+Sexual+Behavior+that+Increases+Risk+of+Acquiring+and+Transmitting+HIV+Infection+Among+Black+Men+Who+Have+Sex+with+Men&rft.au=Jeffries%2C+William+L%3BMarks%2C+Gary%3BLauby%2C+Jennifer%3BMurrill%2C+Christopher+S%3BMillett%2C+Gregorio+A&rft.aulast=Jeffries&rft.aufirst=William&rft.date=2013-05-01&rft.volume=17&rft.issue=4&rft.spage=1442&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-012-0189-y LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Number of references - 45 N1 - Last updated - 2015-03-04 N1 - SubjectsTermNotLitGenreText - Sexuality; Integration; Regression analysis; Infection; Sexual behavior; Social interactions; Sex; Disease transmission; Acquired immune deficiency syndrome; Human immunodeficiency virus; Intervention; Risk taking; Anal sex; Homosexuality DO - http://dx.doi.org/10.1007/s10461-012-0189-y ER - TY - JOUR T1 - Common source outbreaks of Campylobacter infection in the USA, 1997-2008 AN - 1367492491; 18084130 AB - Campylobacter is a common but decreasing cause of foodborne infections in the USA. Outbreaks are uncommon and have historically differed from sporadic cases in seasonality and contamination source. We reviewed reported outbreaks of campylobacteriosis. From 1997 to 2008, 262 outbreaks were reported, with 9135 illnesses, 159 hospitalizations, and three deaths. The annual mean was 16 outbreaks for 1997-2002, and 28 outbreaks for 2003-2008. Almost half occurred in warmer months. Foodborne transmission was reported in 225 (86%) outbreaks, water in 24 (9%), and animal contact in seven (3%). Dairy products were implicated in 65 (29%) foodborne outbreaks, poultry in 25 (11%), and produce in 12 (5%). Reported outbreaks increased during a period of declining overall incidence, and seasonality of outbreaks resembled that of sporadic infections. Unlike sporadic illnesses, which are primarily attributed to poultry, dairy products are the most common vehicle identified for outbreaks. JF - Epidemiology and Infection AU - Taylor, E V AU - Herman, K M AU - Ailes, E C AU - Fitzgerald, C AU - Yoder, J S AU - Mahon, B E AU - Tauxe, R V AD - Epidemic Intelligence Service assigned to the Enteric Diseases Epidemiology Branch, Division of Foodborne, Waterborne, and Environmental Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA, idp4@cdc.gov Y1 - 2013/05// PY - 2013 DA - May 2013 SP - 987 EP - 996 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 141 IS - 5 SN - 0950-2688, 0950-2688 KW - Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts KW - Campylobacteriosis KW - USA KW - Campylobacter KW - Outbreaks KW - Infection KW - J 02400:Human Diseases KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1367492491?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Common+source+outbreaks+of+Campylobacter+infection+in+the+USA%2C+1997-2008&rft.au=Taylor%2C+E+V%3BHerman%2C+K+M%3BAiles%2C+E+C%3BFitzgerald%2C+C%3BYoder%2C+J+S%3BMahon%2C+B+E%3BTauxe%2C+R+V&rft.aulast=Taylor&rft.aufirst=E&rft.date=2013-05-01&rft.volume=141&rft.issue=5&rft.spage=987&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268812001744 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-06-01 N1 - Number of references - 1 N1 - Last updated - 2014-03-10 N1 - SubjectsTermNotLitGenreText - Infection; Outbreaks; Campylobacter; USA DO - http://dx.doi.org/10.1017/S0950268812001744 ER - TY - JOUR T1 - Systematic analysis of multiwalled carbon nanotube-induced cellular signaling and gene expression in human small airway epithelial cells. AN - 1328545544; 23377615 AB - Multiwalled carbon nanotubes (MWCNT) are one of the most commonly produced nanomaterials, and pulmonary exposure during production, use, and disposal is a concern for the developing nanotechnology field. The airway epithelium is the first line of defense against inhaled particles. In a mouse model, MWCNT were reported to reach the alveolar space of the lung after in vivo exposure, penetrate the epithelial lining, and result in inflammation and progressive fibrosis. This study sought to determine the cellular and gene expression changes in small airway epithelial cells (SAEC) after in vitro exposure to MWCNT in an effort to elucidate potential toxicity mechanisms and signaling pathways. A direct interaction between SAEC and MWCNT was confirmed by both internalization of MWCNT and interaction at the cell periphery. Following exposure, SAEC showed time-dependent increases in reactive oxygen species production, total protein phosphotyrosine and phosphothreonine levels, and migratory behavior. Analysis of gene and protein expression suggested altered regulation of multiple biomarkers of lung damage, carcinogenesis, and tumor progression, as well as genes involved in related signaling pathways. These results demonstrate that MWCNT exposure resulted in the activation of SAEC. Gene expression data derived from MWCNT exposure provide information that may be used to elucidate the underlying mode of action of MWCNT in the small airway and suggest potential prognostic gene signatures for risk assessment. JF - Toxicological sciences : an official journal of the Society of Toxicology AU - Snyder-Talkington, Brandi N AU - Pacurari, Maricica AU - Dong, Chunlin AU - Leonard, Stephen S AU - Schwegler-Berry, Diane AU - Castranova, Vincent AU - Qian, Yong AU - Guo, Nancy L AD - Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA. ifp1@cdc.gov Y1 - 2013/05// PY - 2013 DA - May 2013 SP - 79 EP - 89 VL - 133 IS - 1 KW - Nanotubes, Carbon KW - 0 KW - Reactive Oxygen Species KW - Index Medicus KW - Real-Time Polymerase Chain Reaction KW - Microscopy, Confocal KW - Reactive Oxygen Species -- metabolism KW - Microscopy, Electron, Transmission KW - Humans KW - Cell Movement -- drug effects KW - Enzyme-Linked Immunosorbent Assay KW - Cell Line KW - Surface Properties KW - Epithelial Cells -- metabolism KW - Respiratory Mucosa -- metabolism KW - Epithelial Cells -- drug effects KW - Nanotubes, Carbon -- chemistry KW - Epithelial Cells -- pathology KW - Signal Transduction -- drug effects KW - Signal Transduction -- genetics KW - Respiratory Mucosa -- drug effects KW - Nanotubes, Carbon -- toxicity KW - Respiratory Mucosa -- pathology KW - Transcriptome -- drug effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1328545544?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.atitle=Systematic+analysis+of+multiwalled+carbon+nanotube-induced+cellular+signaling+and+gene+expression+in+human+small+airway+epithelial+cells.&rft.au=Snyder-Talkington%2C+Brandi+N%3BPacurari%2C+Maricica%3BDong%2C+Chunlin%3BLeonard%2C+Stephen+S%3BSchwegler-Berry%2C+Diane%3BCastranova%2C+Vincent%3BQian%2C+Yong%3BGuo%2C+Nancy+L&rft.aulast=Snyder-Talkington&rft.aufirst=Brandi&rft.date=2013-05-01&rft.volume=133&rft.issue=1&rft.spage=79&rft.isbn=&rft.btitle=&rft.title=Toxicological+sciences+%3A+an+official+journal+of+the+Society+of+Toxicology&rft.issn=1096-0929&rft_id=info:doi/10.1093%2Ftoxsci%2Fkft019 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2013-10-17 N1 - Date created - 2013-04-17 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: J Toxicol Environ Health A. 2012;75(3):129-47 [22251262] J Toxicol Environ Health A. 2012;75(18):1129-53 [22891886] Curr Opin Cell Biol. 2001 Apr;13(2):131-8 [11248545] Cell. 2004 Jan 23;116(2):191-203 [14744431] Environ Health Perspect. 1994 Dec;102 Suppl 10:33-6 [7705301] J Biol Chem. 2005 Feb 4;280(5):3875-84 [15492012] Carcinogenesis. 2005 Apr;26(4):725-31 [15677631] Respirology. 2006 Jan;11 Suppl:S12-5 [16423262] Science. 2006 Feb 3;311(5761):622-7 [16456071] Clin Cancer Res. 2006 Jun 1;12(11 Pt 1):3344-54 [16740756] Toxicol Lett. 2007 Jan 10;168(1):58-74 [17141434] Environ Health Perspect. 2006 Dec;114(12):1818-25 [17185269] Proc Am Thorac Soc. 2008 Apr 15;5(3):305-10 [18403324] Inhal Toxicol. 2008 Jun;20(8):741-9 [18569096] Clin Cancer Res. 2008 Dec 15;14(24):8213-20 [19088038] Biochem Biophys Res Commun. 2009 Feb 6;379(2):643-8 [19121628] Curr Opin Cell Biol. 2009 Apr;21(2):140-6 [19269802] J Toxicol Environ Health A. 2010;73(5):378-95 [20155580] Pharmacol Ther. 2010 Mar;125(3):376-93 [19945483] Toxicology. 2010 Mar 10;269(2-3):136-47 [19857541] Part Fibre Toxicol. 2010;7:5 [20307263] PLoS One. 2010;5(8):e12222 [20808922] Part Fibre Toxicol. 2010;7:28 [20920331] J Occup Environ Med. 2011 Jun;53(6 Suppl):S14-7 [21606847] Ther Adv Respir Dis. 2011 Aug;5(4):255-73 [21372121] Toxicol Appl Pharmacol. 2011 Aug 15;255(1):18-31 [21624382] Part Fibre Toxicol. 2011;8:21 [21781304] Oxid Med Cell Longev. 2011;2011:809696 [21904647] Chem Res Toxicol. 2011 Dec 19;24(12):2237-48 [22081859] Erratum In: Toxicol Sci. 2013 Aug;134(2):427 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1093/toxsci/kft019 ER - TY - JOUR T1 - Sequential Gaussian co-simulation of rate decline parameters of longwall gob gas ventholes AN - 1448721075; 18609192 AB - Gob gas ventholes (GCVs) are used to control methane inflows into a longwall mining operation by capturing the gas within the overlying fractured strata before it enters the work environment. Using geostatistical co-simulation techniques, this paper maps the parameters of their rate decline behaviors across the study area, a longwall mine in the Northern Appalachian basin. Ceostatistical gas-in-place (GIP) simulations were performed, using data from 64 exploration boreholes, and CIP data were mapped within the fractured zone of the study area. In addition, methane flowrates monitored from 10 GGVs were analyzed using decline curve analyses (DCA) techniques to determine parameters of decline rates. Surface elevation showed the most influence on methane production from CCVs and thus was used to investigate its relation with DCA parameters using correlation techniques on normal-scored data. Geostatistical analysis was pursued using sequential Gaussian co-simulation with surface elevation as the secondary variable and with DCA parameters as the primary variables. The primary DCA variables were effective percentage decline rate, rate at production start, rate at the beginning of forecast period, and production end duration. Co-simulation results were presented to visualize decline parameters at an area-wide scale. Wells located at lower elevations, i.e., at the bottom of valleys, tend to perform better in terms of their rate declines compared to those at higher elevations. These results were used to calculate drainage radii of GGVs using GIP realizations. The calculated drainage radii are close to ones predicted by pressure transient tests. JF - International Journal of Rock Mechanics and Mining Sciences AU - Karacan, COe AU - Olea, R A AD - NIOSH, Office of Mine Safety and Health Research, Pittsburgh, PA, United States, cok6@cdc.gov Y1 - 2013/04// PY - 2013 DA - Apr 2013 SP - 1 EP - 14 PB - Elsevier B.V., P.O. Box 800 Kidlington Oxford OX5 1DX United Kingdom VL - 59 SN - 1365-1609, 1365-1609 KW - Water Resources Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources KW - Testing Procedures KW - Methane KW - Drainage KW - USA, Appalachian Basin KW - Maps KW - Boreholes KW - Rock Mechanics KW - Rock mechanics KW - Behavior KW - Elevation KW - Exploration KW - Mining KW - Q2 09188:Atmospheric chemistry KW - SW 5080:Evaluation, processing and publication UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1448721075?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Rock+Mechanics+and+Mining+Sciences&rft.atitle=Sequential+Gaussian+co-simulation+of+rate+decline+parameters+of+longwall+gob+gas+ventholes&rft.au=Karacan%2C+COe%3BOlea%2C+R+A&rft.aulast=Karacan&rft.aufirst=COe&rft.date=2013-04-01&rft.volume=59&rft.issue=&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Rock+Mechanics+and+Mining+Sciences&rft.issn=13651609&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-11-01 N1 - Last updated - 2015-03-20 N1 - SubjectsTermNotLitGenreText - Methane; Rock mechanics; Mining; Boreholes; Testing Procedures; Rock Mechanics; Behavior; Drainage; Elevation; Exploration; Maps; USA, Appalachian Basin ER - TY - JOUR T1 - Pulmonary and Cardiovascular Responses of Rats to Inhalation of Silver Nanoparticles AN - 1439229201; 18602046 AB - Exposure to wet aerosols generated during use of spray products containing silver (Ag) has not been evaluated. The goal was to assess the potential for cardiopulmonary toxicity following an acute inhalation of wet silver colloid. Rats were exposed by inhalation to a low concentration (100 mu g/m super(3) ) using an undiluted commercial antimicrobial product (20 mg/L total silver; approximately 33 nm mean aerodynamic diameter [MAD]) or to a higher concentration (1000 mu g/m super(3)) using a suspension (200 mg/L total silver; approximately 39 nm MAD) synthesized to possess a similar size distribution of Ag nanoparticles for 5 h. Estimated lung burdens from deposition models were 0, 1.4, or 14 mu g Ag/rat after exposure to control aerosol, low, and high doses, respectively. At 1 and 7 d postexposure, the following parameters were monitored: pulmonary inflammation, lung cell toxicity, alveolar air/blood barrier damage, alveolar macrophage activity, blood cell differentials, responsiveness of tail artery to vasoconstrictor or vasodilatory agents, and heart rate and blood pressure in response to isoproterenol or norepinephrine, respectively. Changes in pulmonary or cardiovascular parameters were absent or nonsignificant at 1 or 7 d postexposure with the exceptions of increased blood monocytes 1 d after high-dose Ag exposure and decreased dilation of tail artery after stimulation, as well as elevated heart rate in response to isoproterenol 1 d after low-dose Ag exposure, possibly due to bioavailable ionic Ag in the commercial product. In summary, short-term inhalation of nano-Ag did not produce apparent marked acute toxicity in this animal model. JF - Journal of Toxicology and Environmental Health, Part A: Current Issues AU - Roberts, Jenny R AU - McKinney, Walter AU - Kan, Hong AU - Krajnak, Kristine AU - Frazer, David G AU - Thomas, Treye A AU - Waugh, Stacey AU - Kenyon, Allison AU - MacCuspie, Robert I AU - Hackley, Vincent A AU - Castranova, Vincent AD - National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA, jur6@cdc.gov Y1 - 2013/04/01/ PY - 2013 DA - 2013 Apr 01 SP - 651 EP - 668 PB - Taylor & Francis Group Ltd., 2 Park Square Oxford OX14 4RN United Kingdom VL - 76 IS - 11 SN - 1528-7394, 1528-7394 KW - Pollution Abstracts; Environment Abstracts; Toxicology Abstracts KW - Inhalation KW - Macrophages KW - Cardiovascular system KW - Vasoconstrictors KW - Arteries KW - Heart rate KW - Animal models KW - Acute toxicity KW - Blood pressure KW - Rats KW - Blood cells KW - Monocytes KW - Aerosols KW - Tails KW - Sprays KW - Toxicity KW - Alveoli KW - Antimicrobial agents KW - Pollutant deposition KW - Lung KW - isoproterenol KW - nanoparticles KW - Silver KW - P 0000:AIR POLLUTION KW - X 24360:Metals KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1439229201?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.atitle=Pulmonary+and+Cardiovascular+Responses+of+Rats+to+Inhalation+of+Silver+Nanoparticles&rft.au=Roberts%2C+Jenny+R%3BMcKinney%2C+Walter%3BKan%2C+Hong%3BKrajnak%2C+Kristine%3BFrazer%2C+David+G%3BThomas%2C+Treye+A%3BWaugh%2C+Stacey%3BKenyon%2C+Allison%3BMacCuspie%2C+Robert+I%3BHackley%2C+Vincent+A%3BCastranova%2C+Vincent&rft.aulast=Roberts&rft.aufirst=Jenny&rft.date=2013-04-01&rft.volume=76&rft.issue=11&rft.spage=651&rft.isbn=&rft.btitle=&rft.title=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.issn=15287394&rft_id=info:doi/10.1080%2F15287394.2013.792024 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-10-01 N1 - Last updated - 2015-03-20 N1 - SubjectsTermNotLitGenreText - Macrophages; Inhalation; Aerosols; Cardiovascular system; Vasoconstrictors; Tails; Arteries; Heart rate; Animal models; Acute toxicity; Blood pressure; Alveoli; Antimicrobial agents; Lung; isoproterenol; Monocytes; Blood cells; Silver; nanoparticles; Rats; Pollutant deposition; Sprays; Toxicity DO - http://dx.doi.org/10.1080/15287394.2013.792024 ER - TY - JOUR T1 - A tool for enhancing strategic health planning: a modeled use of the International Classification of Functioning, Disability and Health AN - 1430186796; 201319626 AB - This article describes use of the International Classification of Functioning, Disability and Health (ICF) as a tool for strategic planning. The ICF is the international classification system for factors that influence health, including Body Structures, Body Functions, Activities and Participation and Environmental Factors. An overview of strategic planning and the ICF are provided. Selected ICF concepts and nomenclature are used to demonstrate its utility in helping develop a classic planning framework, objectives, measures and actions. Some issues and resolutions for applying the ICF are described. Applying the ICF for strategic health planning is an innovative approach that fosters the inclusion of social ecological health determinants and broad populations. If employed from the onset of planning, the ICF can help public health organizations systematically conceptualize, organize and communicate a strategic health plan. This article is a US Government work and is in the public domain in the USA. [Copyright John Wiley and Sons, Ltd.] JF - The International Journal of Health Planning and Management AU - Sinclair, Lisa Bundara AU - Fox, Michael H AU - Betts, Donald R AD - Disability and Health, NCBDDD, CDC, DHHS, 1600 Clifton Rd (E-88), Atlanta, GA 30333, USA lsinclair@cdc.gov Y1 - 2013/04// PY - 2013 DA - April 2013 SP - 172 EP - 180 PB - John Wiley & Sons, Chichester UK VL - 28 IS - 2 SN - 0749-6753, 0749-6753 KW - health determinants, International Classification of Functioning Disability and Health (ICF), public health, strategic planning KW - Strategic planning KW - Classification KW - Environmental aspects KW - Disability KW - Health KW - Public health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1430186796?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+International+Journal+of+Health+Planning+and+Management&rft.atitle=A+tool+for+enhancing+strategic+health+planning%3A+a+modeled+use+of+the+International+Classification+of+Functioning%2C+Disability+and+Health&rft.au=Sinclair%2C+Lisa+Bundara%3BFox%2C+Michael+H%3BBetts%2C+Donald+R&rft.aulast=Sinclair&rft.aufirst=Lisa&rft.date=2013-04-01&rft.volume=28&rft.issue=2&rft.spage=172&rft.isbn=&rft.btitle=&rft.title=The+International+Journal+of+Health+Planning+and+Management&rft.issn=07496753&rft_id=info:doi/10.1002%2Fhpm.2125 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2013-09-01 N1 - Last updated - 2016-09-27 N1 - CODEN - IJHMEO N1 - SubjectsTermNotLitGenreText - Health; Classification; Strategic planning; Disability; Environmental aspects; Public health DO - http://dx.doi.org/10.1002/hpm.2125 ER - TY - JOUR T1 - Commentary on Subgroup Analysis in Intervention Research: Opportunities for the Public Health Approach to Violence Prevention AN - 1352283050; 17894420 AB - The public health approach to prevention places a unique emphasis on understanding which populations are at greatest risk for poor health; the factors that place different populations at risk for experiencing injury, death, disability, and related health outcomes; the preventive interventions that are most effective for universal, selected, and indicated populations; and the best methods for encouraging the translation, dissemination, and adoption of preventive interventions for various populations. This information can be valuable in maximizing the efficiency and effectiveness of public health prevention approaches. The present article provides a commentary on the contributions of rigorous subgroup analysis to intervention research and, in particular, the Centers for Disease Control and Prevention's (CDC) public health approach to violence prevention. JF - Prevention Science AU - Haegerich, Tamara M AU - Massetti, Greta M AD - Centers for Disease Control and Prevention, 4770 Buford Highway, NE, MS F-64, Atlanta, GA, 30341, USA, GMassetti@cdc.gov Y1 - 2013/04// PY - 2013 DA - Apr 2013 SP - 193 EP - 198 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 14 IS - 2 SN - 1389-4986, 1389-4986 KW - Health & Safety Science Abstracts KW - Mortality KW - Prevention KW - Injuries KW - Disabilities KW - Disease control KW - Intervention KW - Violence KW - Public health KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1352283050?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Prevention+Science&rft.atitle=Commentary+on+Subgroup+Analysis+in+Intervention+Research%3A+Opportunities+for+the+Public+Health+Approach+to+Violence+Prevention&rft.au=Haegerich%2C+Tamara+M%3BMassetti%2C+Greta+M&rft.aulast=Haegerich&rft.aufirst=Tamara&rft.date=2013-04-01&rft.volume=14&rft.issue=2&rft.spage=193&rft.isbn=&rft.btitle=&rft.title=Prevention+Science&rft.issn=13894986&rft_id=info:doi/10.1007%2Fs11121-012-0331-0 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-05-01 N1 - Number of references - 14 N1 - Last updated - 2013-05-31 N1 - SubjectsTermNotLitGenreText - Mortality; Prevention; Injuries; Disabilities; Disease control; Intervention; Violence; Public health DO - http://dx.doi.org/10.1007/s11121-012-0331-0 ER - TY - JOUR T1 - Aminoglycoside Cross-Resistance in Mycobacterium tuberculosis Due to Mutations in the 5' Untranslated Region of whiB7 AN - 1348482992; 17882185 AB - Since the discovery of streptomycin's bactericidal activity against Mycobacterium tuberculosis, aminoglycosides have been utilized to treat tuberculosis (TB). Today, the aminoglycosides kanamycin and amikacin are used to treat multidrug-resistant (MDR) TB, and resistance to any of the second-line injectable antibiotics, including kanamycin, amikacin, or capreomycin, is a defining characteristic of extensively drug-resistant (XDR) TB. Resistance to kanamycin and streptomycin is thought to be due to the acquisition of unlinked chromosomal mutations. However, we identified eight independent mutations in the 5' untranslated region of the transcriptional activator whiB7 that confer low-level resistance to both aminoglycosides. The mutations lead to 23- to 145-fold increases in whiB7 transcripts and subsequent increased expression of both eis (Rv2416c) and tap (Rv1258c). Increased expression of eis confers kanamycin resistance in these mutants, while increased expression of tap, which encodes an efflux pump, is a previously uncharacterized mechanism of low-level streptomycin resistance. Additionally, high-level resistance to streptomycin arose at a much higher frequency in whiB7 mutants than in a wild-type (WT) strain. Although whiB7 is typically associated with intrinsic antibiotic resistance in M. tuberculosis, these data suggest that mutations in an uncharacterized regulatory region of whiB7 contribute to cross-resistance against clinically used second-line antibiotics. As drug resistance continues to develop and spread, understanding the mechanisms and molecular basis of antibiotic resistance is critical for the development of rapid molecular tests to diagnose drug-resistant TB strains and ultimately for designing regimens to treat drug-resistant cases of TB. JF - Antimicrobial Agents & Chemotherapy AU - Reeves, Analise Z AU - Campbell, Patricia J AU - Sultana, Razvan AU - Malik, Seidu AU - Murray, Megan AU - Plikaytis, Bonnie B AU - Shinnick, Thomas M AU - Posey, James E AD - Microbiology and Molecular Genetics Graduate Program, Department of Microbiology and Immunology, Emory University, Atlanta, Georgia, USA, jposey@cdc.gov Y1 - 2013/04// PY - 2013 DA - Apr 2013 SP - 1857 EP - 1865 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 57 IS - 4 SN - 0066-4804, 0066-4804 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Data processing KW - Amikacin KW - Regulatory sequences KW - Drug resistance KW - Transcription KW - Antibiotics KW - Kanamycin KW - Streptomycin KW - Aminoglycoside antibiotics KW - Capreomycin KW - Tuberculosis KW - Cross-resistance KW - Mutation KW - Bactericidal activity KW - Antibiotic resistance KW - Mycobacterium tuberculosis KW - A 01350:Microbial Resistance KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1348482992?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Aminoglycoside+Cross-Resistance+in+Mycobacterium+tuberculosis+Due+to+Mutations+in+the+5%27+Untranslated+Region+of+whiB7&rft.au=Reeves%2C+Analise+Z%3BCampbell%2C+Patricia+J%3BSultana%2C+Razvan%3BMalik%2C+Seidu%3BMurray%2C+Megan%3BPlikaytis%2C+Bonnie+B%3BShinnick%2C+Thomas+M%3BPosey%2C+James+E&rft.aulast=Reeves&rft.aufirst=Analise&rft.date=2013-04-01&rft.volume=57&rft.issue=4&rft.spage=1857&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.02191-12 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-05-01 N1 - Number of references - 37 N1 - Last updated - 2013-05-31 N1 - SubjectsTermNotLitGenreText - Data processing; Amikacin; Drug resistance; Regulatory sequences; Transcription; Kanamycin; Antibiotics; Streptomycin; Aminoglycoside antibiotics; Capreomycin; Tuberculosis; Bactericidal activity; Mutation; Cross-resistance; Antibiotic resistance; Mycobacterium tuberculosis DO - http://dx.doi.org/10.1128/AAC.02191-12 ER - TY - JOUR T1 - The Concrete Jungle: City Stress and Substance Abuse among Young Adult African American Men AN - 1328514264; 17845800 AB - Substance use is prevalent among African American men living in urban communities. The impact of substance use on the social, psychological, and physical health of African American men has important public health implications for families, communities, and society. Given the adverse consequences of alcohol and drug abuse within communities of color, this study evaluated the relationship between city stress, alcohol consumption, and drug use among African American men. Eighty heterosexual, African American men, 18 to 29 years old, completed psychosocial risk assessments that assessed substance use and city stress. Multiple logistic regression analyses, controlling for age, indicated that participants reporting high levels of urban stress, relative to low levels of urban stress, were more likely to report a history of marijuana use (AOR=5.19, p=.05), history of ecstasy and/or GHB use (AOR=3.34, p=.04), having family/friends expressing strong concerns about their illicit drug use (AOR=4.06, p=.02), and being unable to remember what happened the night before due to drinking (AOR=4.98, p=.01). African American men living within the confines of a stressful urban environment are at increased risk for exposure to and utilization of illicit substances. Culturally competent public health interventions for substance use/abuse should address psychological factors, such as stress and neighborhood violence. JF - Journal of Urban Health AU - Seth, Puja AU - Murray, Colleen C AU - Braxton, Nikia D AU - DiClemente, Ralph J AD - Department of Behavioral Sciences and Health Education, Rollins School of Public Health, Emory University, Atlanta, GA, USA, pseth@cdc.gov Y1 - 2013/04// PY - 2013 DA - Apr 2013 SP - 307 EP - 313 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 90 IS - 2 SN - 1099-3460, 1099-3460 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Alcohol KW - Ethnic groups KW - R2 23110:Psychological aspects KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1328514264?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Urban+Health&rft.atitle=The+Concrete+Jungle%3A+City+Stress+and+Substance+Abuse+among+Young+Adult+African+American+Men&rft.au=Seth%2C+Puja%3BMurray%2C+Colleen+C%3BBraxton%2C+Nikia+D%3BDiClemente%2C+Ralph+J&rft.aulast=Seth&rft.aufirst=Puja&rft.date=2013-04-01&rft.volume=90&rft.issue=2&rft.spage=307&rft.isbn=&rft.btitle=&rft.title=Journal+of+Urban+Health&rft.issn=10993460&rft_id=info:doi/10.1007%2Fs11524-012-9716-4 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-04-01 N1 - Number of references - 1 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Ethnic groups DO - http://dx.doi.org/10.1007/s11524-012-9716-4 ER - TY - JOUR T1 - Inactivation of infectious virus and serological detection of virus antigen in Rift Valley fever virus-exposed mosquitoes fixed with paraformaldehyde AN - 1328512038; 17847826 AB - Formaldehyde is routinely used to fix tissues in preparation for pathology studies, however concerns remain that treatment of tissues with cellular fixatives may not entirely inactivate infectious virus particles. This concern is of particular regulatory importance for research involving viruses that are classified as select agents such as Rift Valley fever virus (RVFV). Therefore, the specific aims of this study were to (1) assay RVFV-exposed Aedes aegypti mosquitoes fixed in 4% paraformaldehyde for the presence of infectious RVFV particles at various time points following infection and (2) demonstrate the utility of immunofluorescence assay (IFA) for the detection of RVFV antigen in various tissues of paraformaldehyde-fixed mosquitoes. Mosquitoes were administered an infectious blood meal containing one of two strains of RVFV, harvested at various time points following infection, intrathoracically inoculated with 4% paraformaldehyde, and fixed overnight at 4 degree C. The infection status of a subset of mosquitoes was verified by IFA on leg tissues prior to fixation, and infectivity of RVFV in fixed mosquito carcasses was determined by Vero cell plaque assay. Paraformaldehyde-fixed mosquitoes harvested 14 days post infection were also paraffin-embedded and sectioned for detection of RVFV antigen to particular tissues by IFA. None of the RVFV-exposed mosquitoes tested by Vero cell plaque assay contained infectious RVFV after fixation. Furthermore, incubation of mosquito sections with trypsin prior to antibody staining is recommended for optimal visualization of RVFV antigen in infected mosquito tissues by IFA. JF - Journal of Virological Methods AU - Kading, Rebekah AU - Crabtree, Mary AU - Miller, Barry AD - Centers for Disease Control and Prevention, Division of Vector-borne Diseases, Arbovirus Diseases Branch, 3156 Rampart Road, Mail Stop P02, Fort Collins, CO 80521, USA, fxk7@cdc.gov Y1 - 2013/04// PY - 2013 DA - April 2013 SP - 184 EP - 188 PB - Elsevier B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 189 IS - 1 SN - 0166-0934, 0166-0934 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Virology & AIDS Abstracts KW - Rift Valley fever virus KW - Paraformaldehyde fixation KW - Trypsin KW - Mosquito KW - Pathology KW - Aedes aegypti KW - Viruses KW - Formaldehyde KW - Rift Valley fever KW - Blood meals KW - Infection KW - Public health KW - Antigens KW - Carcasses KW - Fixatives KW - Aquatic insects KW - Rift valleys KW - Vero cells KW - Immunofluorescence KW - Leg KW - Infectivity KW - Antibodies KW - Viral diseases KW - Plaque assay KW - V 22300:Methods KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1328512038?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Virological+Methods&rft.atitle=Inactivation+of+infectious+virus+and+serological+detection+of+virus+antigen+in+Rift+Valley+fever+virus-exposed+mosquitoes+fixed+with+paraformaldehyde&rft.au=Kading%2C+Rebekah%3BCrabtree%2C+Mary%3BMiller%2C+Barry&rft.aulast=Kading&rft.aufirst=Rebekah&rft.date=2013-04-01&rft.volume=189&rft.issue=1&rft.spage=184&rft.isbn=&rft.btitle=&rft.title=Journal+of+Virological+Methods&rft.issn=01660934&rft_id=info:doi/10.1016%2Fj.jviromet.2013.01.014 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-04-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Carcasses; Antigens; Pathology; Viral diseases; Viruses; Immunofluorescence; Rift valleys; Aquatic insects; Public health; Vero cells; Trypsin; Formaldehyde; Rift Valley fever; Blood meals; Infection; Leg; Antibodies; Infectivity; Fixatives; Plaque assay; Aedes aegypti; Rift Valley fever virus DO - http://dx.doi.org/10.1016/j.jviromet.2013.01.014 ER - TY - JOUR T1 - Occupational exposure assessment in carbon nanotube and nanofiber primary and secondary manufacturers: mobile direct-reading sampling. AN - 1317405506; 23100605 AB - RESEARCH SIGNIFICANCE: Toxicological evidence suggests the potential for a wide range of health effects from exposure to carbon nanotubes (CNTs) and carbon nanofibers (CNFs). To date, there has been much focus on the use of direct-reading instruments (DRIs) to assess multiple airborne exposure metrics for potential exposures to CNTs and CNFs due to their ease of use and ability to provide instantaneous results. Still, uncertainty exists in the usefulness and interpretation of the data. To address this gap, air-monitoring was conducted at six sites identified as CNT and CNF manufacturers or users and results were compared with filter-based metrics. Particle number, respirable mass, and active surface area concentrations were monitored with a condensation particle counter, a photometer, and a diffusion charger, respectively. The instruments were placed on a mobile cart and used as area monitors in parallel with filter-based elemental carbon (EC) and electron microscopy samples. Repeat samples were collected on consecutive days, when possible, during the same processes. All instruments in this study are portable and routinely used for industrial hygiene sampling. Differences were not observed among the various sampled processes compared with concurrent indoor or outdoor background samples while examining the different DRI exposure metrics. Such data were also inconsistent with results for filter-based samples collected concurrently at the same sites [Dahm MM, Evans DE, Schubauer-Berigan MK et al. (2012) Occupational exposure assessment in CNT and nanofiber primary and secondary manufacturers. Ann Occup Hyg; 56: 542-56]. Significant variability was seen between these processes as well as the indoor and outdoor backgrounds. However, no clear pattern emerged linking the DRI results to the EC or the microscopy data (CNT and CNF structure counts). Overall, no consistent trends were seen among similar processes at the various sites. The DRI instruments employed were limited in their usefulness in assessing and quantifying potential exposures at the sampled sites but were helpful for hypothesis generation, control technology evaluations, and other air quality issues. The DRIs employed are nonspecific, aerosol monitors, and, therefore, subject to interferences. As such, it is necessary to collect samples for analysis by more selective, time-integrated, laboratory-based methods to confirm and quantify exposures. JF - The Annals of occupational hygiene AU - Dahm, Matthew M AU - Evans, Douglas E AU - Schubauer-Berigan, Mary K AU - Birch, M Eileen AU - Deddens, James A AD - Division of Surveillance, Hazard Evaluations, and Field Studies, Industrywide Studies Branch, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, MS-R14, Cincinnati, OH 45226, USA. mdahm@cdc.gov Y1 - 2013/04// PY - 2013 DA - April 2013 SP - 328 EP - 344 VL - 57 IS - 3 KW - Air Pollutants, Occupational KW - 0 KW - Nanotubes, Carbon KW - Carbon KW - 7440-44-0 KW - Index Medicus KW - Environmental Monitoring KW - Occupational Health KW - Microscopy, Electron, Transmission KW - Inhalation Exposure -- prevention & control KW - Inhalation Exposure -- analysis KW - Humans KW - Carbon -- analysis KW - Nanostructures -- analysis KW - Nanotubes, Carbon -- toxicity KW - Occupational Exposure -- prevention & control KW - Air Pollutants, Occupational -- analysis KW - Occupational Exposure -- analysis KW - Nanofibers -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1317405506?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Annals+of+occupational+hygiene&rft.atitle=Occupational+exposure+assessment+in+carbon+nanotube+and+nanofiber+primary+and+secondary+manufacturers%3A+mobile+direct-reading+sampling.&rft.au=Dahm%2C+Matthew+M%3BEvans%2C+Douglas+E%3BSchubauer-Berigan%2C+Mary+K%3BBirch%2C+M+Eileen%3BDeddens%2C+James+A&rft.aulast=Dahm&rft.aufirst=Matthew&rft.date=2013-04-01&rft.volume=57&rft.issue=3&rft.spage=328&rft.isbn=&rft.btitle=&rft.title=The+Annals+of+occupational+hygiene&rft.issn=1475-3162&rft_id=info:doi/10.1093%2Fannhyg%2Fmes079 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2014-03-03 N1 - Date created - 2013-03-13 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Ann Occup Hyg. 2011 Nov;55(9):1037-47 [21976308] Ann Occup Hyg. 2010 Jul;54(5):514-31 [20447936] Ann Occup Hyg. 2012 Jul;56(5):542-56 [22156567] Ann Occup Hyg. 2012 Jul;56(5):606-21 [22752099] Int J Occup Environ Health. 2010 Oct-Dec;16(4):365-77 [21222381] Int J Occup Environ Health. 2010 Oct-Dec;16(4):434-50 [21222387] J Occup Environ Hyg. 2011 Feb;8(2):86-92 [21253981] Biochim Biophys Acta. 2011 Mar;1810(3):361-73 [20435096] J Occup Environ Hyg. 2011 Nov;8(11):673-85 [22023547] Ann Occup Hyg. 2012 Jan;56(1):1-9 [22156566] Ann Occup Hyg. 2013 Mar;57(2):261-77 [23065675] Am J Physiol Lung Cell Mol Physiol. 2008 Jan;294(1):L87-97 [18024722] J Toxicol Environ Health A. 2004 Jan 9;67(1):87-107 [14668113] J Occup Environ Hyg. 2005 Jan;2(1):45-53 [15764523] Environ Health Perspect. 2005 Jul;113(7):823-39 [16002369] Crit Rev Toxicol. 2006 Mar;36(3):189-217 [16686422] J Occup Environ Hyg. 2007 May;4(5):341-51 [17454502] Yonsei Med J. 2007 Aug 31;48(4):561-72 [17722227] Ann Occup Hyg. 2008 Jan;52(1):9-21 [18056626] J Occup Environ Med. 2008 May;50(5):517-26 [18469620] Inhal Toxicol. 2008 Jun;20(8):741-9 [18569096] Am J Physiol Lung Cell Mol Physiol. 2008 Oct;295(4):L552-65 [18658273] J Occup Environ Hyg. 2009 Jan;6(1):19-31 [18982535] Ann Occup Hyg. 2008 Nov;52(8):695-706 [18931382] J Occup Environ Hyg. 2009 Feb;6(2):73-81 [19034793] Inhal Toxicol. 2009 Jul;21 Suppl 1:25-9 [19558230] Inhal Toxicol. 2009 Jul;21 Suppl 1:68-73 [19558236] Environ Sci Technol. 2009 Aug 1;43(15):6017-23 [19731712] Environ Mol Mutagen. 2009 Oct;50(8):708-17 [19774611] Ann Occup Hyg. 2009 Nov;53(8):829-38 [19703918] J Occup Environ Hyg. 2010 Mar;7(3):127-32 [20017054] Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2009 Jan-Feb;1(1):26-34 [20049776] J Occup Environ Hyg. 2010 Mar;7(3):163-76 [20063229] Inhal Toxicol. 2010 Apr;22(5):369-81 [20121582] Ann Occup Hyg. 2011 Nov;55(9):1016-36 [21965464] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1093/annhyg/mes079 ER - TY - JOUR T1 - Development and Evaluation of Fire Barriers to Reduce Fire Hazards on large mining Equipment AN - 1291614052; 17670599 AB - The National Institute for Occupational Safety and Health has developed and evaluated various fire barriers for their effectiveness in preventing the spraying of pressurized hydraulic fluids onto simulated turbocharger hot surfaces, and in preventing the ignition of flammable vapors and mists onto barrier outer surfaces. This initial study, however, needs to be followed by a larger investigation that deals with barrier effectiveness in preventing or reducing hydraulic fluid fires within compartments of operating equipment, and barrier physical endurance under hostile environments within compartments. Some of the barriers were also evaluated for their effectiveness in suppressing simulated turbocharger fast-developing fires (initial fires, 32 kW). For the evaluation, modeled engine compartments with simulated turbocharger surfaces of 600 degree C, initial fires of 32 kW, and a pressurized hydraulic fluid spray system, were used. Also, conceptualized designs of some of the fire barriers, set within the compartments of typical mining equipment, have been reported to provide further guidance toward barrier fabrication and installation. The fire barriers included a parachute silica cloth barrier lined with flexible stainless steel foil; a one-panel insulated stainless steel barrier with a water-spray system; a foldable multi-panel insulated stainless steel barrier; and, an open-close steel strip barrier. Results show that all four fire barriers were effective in preventing the spraying of pressurized hydraulic fluids onto simulated turbocharger hot surfaces. Most of the barriers were also effective in preventing the ignition of flammable vapors and mists onto barrier outer surfaces. Results also show that the parachute barrier and the one-panel barrier with a water-spray system were effective in suppressing simulated turbocharger initial fires of 32 kW. JF - Fire Technology AU - Rosa, Maria I AU - Litton, Charles D AD - Pittsburgh Research Laboratory, National Institute for Occupational Safety and Health, Pittsburgh, PA, USA, mgd8@CDC.gov Y1 - 2013/04// PY - 2013 DA - Apr 2013 SP - 253 EP - 268 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 49 IS - 2 SN - 0015-2684, 0015-2684 KW - Environment Abstracts; Health & Safety Science Abstracts; Risk Abstracts KW - Mining equipment KW - Fires KW - Hydraulics KW - Vapors KW - Silica KW - Mists KW - Sprays KW - Occupational safety KW - Flammability KW - Steel KW - Fire hazards KW - R2 23080:Industrial and labor KW - H 1000:Occupational Safety and Health KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1291614052?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Fire+Technology&rft.atitle=Development+and+Evaluation+of+Fire+Barriers+to+Reduce+Fire+Hazards+on+large+mining+Equipment&rft.au=Rosa%2C+Maria+I%3BLitton%2C+Charles+D&rft.aulast=Rosa&rft.aufirst=Maria&rft.date=2013-04-01&rft.volume=49&rft.issue=2&rft.spage=253&rft.isbn=&rft.btitle=&rft.title=Fire+Technology&rft.issn=00152684&rft_id=info:doi/10.1007%2Fs10694-012-0258-9 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-01 N1 - Number of references - 14 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Mining equipment; Hydraulics; Fires; Vapors; Silica; Mists; Occupational safety; Sprays; Flammability; Fire hazards; Steel DO - http://dx.doi.org/10.1007/s10694-012-0258-9 ER - TY - JOUR T1 - Application of GC-MS/MS for the analysis of tobacco alkaloids in cigarette filler and various tobacco species. AN - 1318095590; 23394466 AB - This publication reports the first known use of gas chromatography-tandem mass spectrometry for the quantitation of five minor tobacco alkaloids (nornicotine, myosmine, anabasine, anatabine, and isonicoteine) in various tobacco samples. A summary of the concentrations of these minor alkaloid levels in the filler from 50 popular cigarette brands were found to be 659-986 μg/g nornicotine, 8.64-17.3 μg/g myosmine, 127-185 μg/g anabasine, 927-1390 μg/g anatabine, and 23.4-45.5 μg/g isonicoteine. Levels of minor alkaloids found in reference cigarettes (1R5F, 2R4F, 3R4F, CM4, and CM6) as well as burley, flue-cured, oriental, reconstituted, and Nicotiana rustica and Nicotiana glauca tobacco types are also reported. Quantitation of the minor tobacco alkaloids is important because the alkaloids have been shown to be precursors of carcinogenic tobacco specific N'-nitrosamines. JF - Analytical chemistry AU - Lisko, Joseph G AU - Stanfill, Stephen B AU - Duncan, Bryce W AU - Watson, Clifford H AD - Tobacco and Volatiles Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, United States. jlisko@cdc.gov Y1 - 2013/03/19/ PY - 2013 DA - 2013 Mar 19 SP - 3380 EP - 3384 VL - 85 IS - 6 KW - Alkaloids KW - 0 KW - Index Medicus KW - Gas Chromatography-Mass Spectrometry -- methods KW - Tobacco -- chemistry KW - Tandem Mass Spectrometry -- methods KW - Tobacco Products -- analysis KW - Alkaloids -- analysis KW - Tobacco -- genetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1318095590?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytical+chemistry&rft.atitle=Application+of+GC-MS%2FMS+for+the+analysis+of+tobacco+alkaloids+in+cigarette+filler+and+various+tobacco+species.&rft.au=Lisko%2C+Joseph+G%3BStanfill%2C+Stephen+B%3BDuncan%2C+Bryce+W%3BWatson%2C+Clifford+H&rft.aulast=Lisko&rft.aufirst=Joseph&rft.date=2013-03-19&rft.volume=85&rft.issue=6&rft.spage=3380&rft.isbn=&rft.btitle=&rft.title=Analytical+chemistry&rft.issn=1520-6882&rft_id=info:doi/10.1021%2Fac400077e LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2014-04-22 N1 - Date created - 2013-03-19 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Forensic Sci Int. 2002 Jul 17;127(3):208-17 [12175951] Anal Chem. 2002 Oct 1;74(19):4878-84 [12380807] Arch Int Pharmacodyn Ther. 1965 Aug;156(2):363-79 [5868944] Int J Cancer. 1991 Feb 1;47(3):348-51 [1993541] J Chromatogr A. 1996 Oct 4;746(1):131-6 [8885385] J Chromatogr A. 2007 Sep 14;1164(1-2):313-9 [17644105] J Med Toxicol. 2011 Mar;7(1):47-51 [20652661] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1021/ac400077e ER - TY - JOUR T1 - Genomics and Autism Spectrum Disorder AN - 1665155842 AB - Purpose: To present the current state of the evidence regarding translation of genetics (the study of single genes) and genomics (the study of all genes and gene-gene or gene-environment interactions) into health care of children with autism spectrum disorder (ASD). Methods: This article presents an overview of ASD as an international health challenge, the emerging science related to broad diagnostic criteria, and the role of the nurse in research, education, and practice. Findings: Much progress is being made in the understanding of genetics and genomics of ASD. Environmental factors are thought to contribute to the risk of developing ASD by interacting with a number of genes in different ways, thus suggesting causal heterogeneity. The rising identified prevalence of ASD, the changing diagnostic criteria for ASD, and the complexity of the core and associated features have made it difficult to define the ASD phenotype (observable behaviors that result from gene-environment interaction). Because early identification improves opportunities for intervention, researchers are looking for a useful biomarker to detect ASD. This search is complicated by the likelihood that there are multiple causes for multiple expressions that are defined as the autism spectrum. Conclusions: To date, genetic and genomic research on ASD have underscored the complexity of the causes of ASD indicating that there are very complex genetic processes involved that are still not well understood. Clinical Relevance: Nurses will benefit from new knowledge related to early identification, diagnosis, and implications for the family to promote early intervention. Families who have a child with ASD will require nursing support for advocacy for optimal health outcomes. JF - Journal of Nursing Scholarship AU - Johnson, Norah L AU - Giarelli, Ellen AU - Lewis, Celine AU - Rice, Catherine E AD - Delta Gamma at Large, Assistant Professor, Marquette University College of Nursing, Milwaukee WI, USA. ; Xi, Associate Professor, Drexel University, College of Nursing and Health Professions, Philadelphia, PA, USA. ; Research Manager, Genetic Alliance UK, London, UK. ; Epidemiologist, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA, USA. ; Delta Gamma at Large, Assistant Professor, Marquette University College of Nursing, Milwaukee WI, USA. Y1 - 2013/03// PY - 2013 DA - Mar 2013 SP - 69 EP - 78 CY - Indianapolis PB - Wiley Subscription Services, Inc. VL - 45 IS - 1 SN - 1527-6546 KW - Medical Sciences--Nurses And Nursing KW - Advocacy KW - Genes KW - Health status KW - Heterogeneity KW - Identification KW - Nurses KW - Nursing KW - Professional identity KW - Professional knowledge KW - Translation KW - Work roles KW - Autistic children KW - Autistic spectrum disorders KW - Behaviour KW - Biological markers KW - Clinical nursing KW - Clinical outcomes KW - Diagnosis KW - Early intervention programmes KW - Environmental aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1665155842?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Nursing+Scholarship&rft.atitle=Genomics+and+Autism+Spectrum+Disorder&rft.au=Johnson%2C+Norah+L%3BGiarelli%2C+Ellen%3BLewis%2C+Celine%3BRice%2C+Catherine+E&rft.aulast=Johnson&rft.aufirst=Norah&rft.date=2013-03-01&rft.volume=45&rft.issue=1&rft.spage=69&rft.isbn=&rft.btitle=&rft.title=Journal+of+Nursing+Scholarship&rft.issn=15276546&rft_id=info:doi/10.1111%2Fj.1547-5069.2012.01483.x LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2015-09-22 N1 - Last updated - 2016-05-16 DO - http://dx.doi.org/10.1111/j.1547-5069.2012.01483.x ER - TY - JOUR T1 - Aflatoxin contamination in food commodities in Bangladesh AN - 1622608931; 17766892 AB - During September 2009, we performed a rapid cross-sectional study to investigate the extent of aflatoxin contamination among common Bangladeshi foods. We collected eight common human food commodities (rice, lentils, wheat flour, dates, betelnut, red chili powder, ginger and groundnuts) and poultry feed samples from two large markets in each of three cities in Bangladesh. We quantified aflatoxin levels from pooled subsamples using fluorescence high-performance liquid chromatography. Aflatoxin levels were highest in dates and groundnuts (maximum 623 and 423 ng/g), respectively. Samples of betelnut (mean 30.6 ng/g), lentils (mean 21.2 ng/g) and red chili powder (>20 ng/g) also had elevated levels. The mean aflatoxin level among poultry feed samples was 73.0 ng/g. Aflatoxin levels were above the US maximum regulatory levels of 20 ng/g in five of eight commonly ingested human food commodities tested. JF - Food Additives & Contaminants: Part B - Surveillance Communications AU - Roy, Monika AU - Harris, Julie AU - Afreen, Sadia AU - Deak, Eszter AU - Gade, Lalitha AU - Balajee, SArunmozhi AU - Park, Benjamin AU - Chiller, Tom AU - Luby, Stephen AD - Centers for Disease Control and Prevention, Mycotic Diseases Branch, Atlanta, GA, USA, ige6@cdc.gov Y1 - 2013/03/01/ PY - 2013 DA - 2013 Mar 01 SP - 17 EP - 23 PB - Taylor & Francis Group Ltd., 2 Park Square Oxford OX14 4RN United Kingdom VL - 6 IS - 1 SN - 1939-3210, 1939-3210 KW - Toxicology Abstracts KW - High-performance liquid chromatography KW - Arachis hypogaea KW - Triticum aestivum KW - Powder KW - Poultry KW - Food additives KW - Fluorescence KW - Aflatoxins KW - Oryza sativa KW - Food contamination KW - X 24320:Food Additives & Contaminants UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1622608931?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Food+Additives+%26+Contaminants%3A+Part+B+-+Surveillance+Communications&rft.atitle=Aflatoxin+contamination+in+food+commodities+in+Bangladesh&rft.au=Roy%2C+Monika%3BHarris%2C+Julie%3BAfreen%2C+Sadia%3BDeak%2C+Eszter%3BGade%2C+Lalitha%3BBalajee%2C+SArunmozhi%3BPark%2C+Benjamin%3BChiller%2C+Tom%3BLuby%2C+Stephen&rft.aulast=Roy&rft.aufirst=Monika&rft.date=2013-03-01&rft.volume=6&rft.issue=1&rft.spage=17&rft.isbn=&rft.btitle=&rft.title=Food+Additives+%26+Contaminants%3A+Part+B+-+Surveillance+Communications&rft.issn=19393210&rft_id=info:doi/10.1080%2F19393210.2012.720617 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-11-01 N1 - Last updated - 2014-11-12 N1 - SubjectsTermNotLitGenreText - High-performance liquid chromatography; Powder; Food additives; Poultry; Fluorescence; Aflatoxins; Food contamination; Triticum aestivum; Arachis hypogaea; Oryza sativa DO - http://dx.doi.org/10.1080/19393210.2012.720617 ER - TY - JOUR T1 - Serial evaluations at an indium-tin oxide production facility AN - 1560136240; 19416412 AB - Background We evaluated the effectiveness of workplace changes to prevent indium lung disease, using 2002-2010 surveillance data collected by an indium-tin oxide production facility. Methods We assessed pulmonary function using lower limits of normal. Blood indium concentration and personal air sampling data were used to estimate exposure. Results Abnormalities were uncommon at hire. After hire, prevalence of spirometric restriction was 31% (n=14/45), about fourfold higher than expected. Excessive decline in FEV1 was elevated at 29% (n=12/41). Half (n=21/42) had blood indium greater than or equal to 5 mu g/l. More recent hires had fewer abnormalities. There was a suggestion that abnormalities were more common among workers with blood indium greater than or equal to 5 mu g/l, but otherwise an exposure-response relationship was not evident. Peak dust concentrations were obscured by time averaging. Conclusions Evolving lung function abnormalities consistent with subclinical indium lung disease appeared common and merit systematic investigation. Traditional measures of exposure and response were not illustrative, suggesting fresh approaches will be needed. Workplace changes seemed to have had a positive though incomplete impact; novel preventive interventions are warranted. Am. J. Ind. Med. 56:300-307, 2013. copyright 2012 Wiley Periodicals, Inc. JF - American Journal of Industrial Medicine AU - Cummings, Kristin J AU - Suarthana, Eva AU - Edwards, Nicole AU - Liang, Xiaoming AU - Stanton, Marcia L AU - Day, Gregory A AU - Saito, Rena AU - Kreiss, Kathleen AD - Epidemic Intelligence Service Program, Centers for Disease Control and Prevention, Atlanta, Georgia., kcummings@cdc.gov Y1 - 2013/03// PY - 2013 DA - Mar 2013 SP - 300 EP - 307 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 56 IS - 3 SN - 0271-3586, 0271-3586 KW - Health & Safety Science Abstracts KW - indium KW - indium-tin oxide KW - interstitial lung disease KW - occupational illness KW - surveillance KW - Lung KW - Indium KW - Dose-response effects KW - Air sampling KW - Intervention KW - Respiratory function KW - Dust KW - Occupational exposure KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1560136240?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Serial+evaluations+at+an+indium-tin+oxide+production+facility&rft.au=Cummings%2C+Kristin+J%3BSuarthana%2C+Eva%3BEdwards%2C+Nicole%3BLiang%2C+Xiaoming%3BStanton%2C+Marcia+L%3BDay%2C+Gregory+A%3BSaito%2C+Rena%3BKreiss%2C+Kathleen&rft.aulast=Cummings&rft.aufirst=Kristin&rft.date=2013-03-01&rft.volume=56&rft.issue=3&rft.spage=300&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=02713586&rft_id=info:doi/10.1002%2Fajim.22125 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Last updated - 2014-10-02 N1 - SubjectsTermNotLitGenreText - Lung; Dose-response effects; Indium; Air sampling; Intervention; Respiratory function; Occupational exposure; Dust DO - http://dx.doi.org/10.1002/ajim.22125 ER - TY - JOUR T1 - Epidemiology of recurrent tuberculosis in the United States, 1993-2010 AN - 1323818643; 17806777 AB - Recurrent tuberculosis (TB) can result from reactivation of a previous TB episode or reinfection with a new Mycobacterium tuberculosis strain. A retrospective analysis of all recurrent TB cases reported in the United States during 1993-2010 was conducted. The proportion of recurrent cases remained stable during the study period (annual range 4.2-5.7%). Compared with persons without a previous diagnosis of TB, persons with recurrent TB experienced lower treatment completion within 12 months and higher mortality during the recurrent episode. Persons with recurrent TB have poorer outcomes, suggesting the need for targeted interventions to ensure treatment completion. JF - International Journal of Tuberculosis and Lung Disease AU - Kim, L AU - Moonan, P K AU - Woodruff, RSY AU - Kammerer, J S AU - Haddad, M B AD - US Centers for Disease Control and Prevention, 1600 Clifton Road, Mailstop C-25, Atlanta, GA 30333, USA, iyn2@cdc.gov Y1 - 2013/03// PY - 2013 DA - Mar 2013 SP - 357 EP - 360 PB - International Union Against Tuberculosis and Lung Disease VL - 17 IS - 3 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts KW - Epidemiology KW - USA KW - Tuberculosis KW - Mycobacterium tuberculosis KW - H 12000:Epidemiology and Public Health KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1323818643?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Epidemiology+of+recurrent+tuberculosis+in+the+United+States%2C+1993-2010&rft.au=Kim%2C+L%3BMoonan%2C+P+K%3BWoodruff%2C+RSY%3BKammerer%2C+J+S%3BHaddad%2C+M+B&rft.aulast=Kim&rft.aufirst=L&rft.date=2013-03-01&rft.volume=17&rft.issue=3&rft.spage=357&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-04-01 N1 - Last updated - 2014-03-10 N1 - SubjectsTermNotLitGenreText - Tuberculosis; Mycobacterium tuberculosis; USA ER - TY - JOUR T1 - Investigating the Potential Public Health Benefit of Jail-based Screening and Treatment Programs for Chlamydia AN - 1323810012; 17767669 AB - Observational studies have found mixed results on the impact of jail-based chlamydia screen-and-treat programs on community prevalence. In the absence of controlled trials or prospectively designed studies, dynamic mathematical models that incorporate movements in and out of jail and sexual contacts (including disease transmission) can provide useful information. We explored the impact of jail-based chlamydia screening on a hypothetical community's prevalence with a deterministic compartmental model focusing on heterosexual transmission. Parameter values were obtained from the published literature. Two analyses were conducted. One used national values (large community); the other used values reported among African Americans-the population with the highest incarceration rates and chlamydia burden (small community). A comprehensive sensitivity analysis was carried out. For the large-community analysis, chlamydia prevalence decreased by 13% (from 2.3% to 2.0%), and based on the ranges of parameter values (including screening coverage of 10%-100% and a postscreening treatment rate of 50%-100%) used in the sensitivity analysis, this decrease ranged from 0.1% to 58%. For the small-community analysis, chlamydia prevalence decreased by 54% (from 4.6% to 2.1%). Jail-based chlamydia screen-and-treat programs have the potential to reduce chlamydia prevalence in communities with high incarceration rates. However, the magnitude of this potential decrease is subject to considerable uncertainty. JF - American Journal of Epidemiology AU - Owusu-Edusei, Kwame AU - Gift, Thomas L AU - Chesson, Harrell W AU - Kent, Charlotte K AD - Correspondence to Dr. Kwame Owusu-Edusei, Jr., Division of STD Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Mailstop E-80, Atlanta, GA 30333, Kowusuedusei@cdc.gov Y1 - 2013/03/01/ PY - 2013 DA - 2013 Mar 01 SP - 463 EP - 473 PB - Oxford University Press, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 177 IS - 5 SN - 0002-9262, 0002-9262 KW - Health & Safety Science Abstracts; Microbiology Abstracts B: Bacteriology; Water Resources Abstracts; Aqualine Abstracts KW - Mathematical Models KW - Clinical trials KW - Disease transmission KW - Public health KW - Sensitivity Analysis KW - Public Health KW - Diseases KW - Sexually transmitted diseases KW - Chlamydia KW - Prisons KW - Mathematical models KW - Model Studies KW - Epidemiology KW - Sensitivity analysis KW - Benefits KW - SW 5010:Network design KW - AQ 00008:Effects of Pollution KW - H 12000:Epidemiology and Public Health KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1323810012?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Epidemiology&rft.atitle=Investigating+the+Potential+Public+Health+Benefit+of+Jail-based+Screening+and+Treatment+Programs+for+Chlamydia&rft.au=Owusu-Edusei%2C+Kwame%3BGift%2C+Thomas+L%3BChesson%2C+Harrell+W%3BKent%2C+Charlotte+K&rft.aulast=Owusu-Edusei&rft.aufirst=Kwame&rft.date=2013-03-01&rft.volume=177&rft.issue=5&rft.spage=463&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Epidemiology&rft.issn=00029262&rft_id=info:doi/10.1093%2Faje%2Fkws240 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-04-01 N1 - Last updated - 2014-05-15 N1 - SubjectsTermNotLitGenreText - Mathematical models; Public health; Disease transmission; Prisons; Sensitivity analysis; Clinical trials; Sexually transmitted diseases; Sensitivity Analysis; Public Health; Mathematical Models; Epidemiology; Diseases; Benefits; Model Studies; Chlamydia DO - http://dx.doi.org/10.1093/aje/kws240 ER - TY - JOUR T1 - Optimization of the Cutoff Value for a Commercial Anti-Dengue Virus IgG Immunoassay AN - 1323803451; 17819205 AB - A commercial anti-dengue virus (anti-DENV) indirect IgG enzyme-linked immunosorbent assay (ELISA) for serological diagnosis was evaluated for its utility in determining previous DENV exposure in U.S. travelers. The Boston Area Travel Medicine Network clinics used Focus Diagnostics anti-DENV IgG ELISA to measure anti-DENV IgG antibodies in 591 pretravel specimens from U.S. residents who had traveled to countries where dengue is endemic. When using the manufacturer's index cutoff value for this ELISA, false-positive results were observed that overestimated the perceived past DENV exposure in U.S. travelers. Validation of 121 of these anti-DENV IgG results by plaque reduction neutralization test (PRNT) was used for receiver operating characteristic (ROC) curve optimization of the index cutoff value from 1 to 3.0, improving the specificity of the anti-DENV IgG ELISA from 24% to 95.7%. Additionally, previous vaccination with yellow fever virus contributed to 52.8% of the false-positive rate in the anti-DENV IgG ELISA results. Optimization of the cutoff value of the anti-DENV IgG ELISA provided better interpretation and confidence in the results and eliminated the need for confirmation by PRNT. The travel history of U.S. travelers was also useful for categorizing these travelers into groups for analysis of previous DENV exposure. JF - Clinical and Vaccine Immunology AU - Marrero-Santos, Karla M AU - Beltran, Manuela AU - Carrion-Lebron, Jessica AU - Sanchez-Vegas, Carolina AU - Hamer, Davidson H AU - Barnett, Elizabeth D AU - Santiago, Luis M AU - Hunsperger, Elizabeth A AD - Dengue Branch, Division of Vector-Borne Diseases, Centers For Disease Control and Prevention, San Juan, Puerto Rico, ElizabethA.Hunsperger,enh4{at}cdc.gov. Y1 - 2013/03// PY - 2013 DA - March 2013 SP - 358 EP - 362 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 20 IS - 3 SN - 1556-6811, 1556-6811 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Virology & AIDS Abstracts; Immunology Abstracts KW - Travel KW - Enzyme-linked immunosorbent assay KW - Specificity KW - Immunology KW - Disease control KW - Vaccination KW - USA, Massachusetts, Boston KW - Yellow fever virus KW - Endemic species KW - Antibodies KW - Dengue KW - Immunoglobulin G KW - ELISA KW - Plaques KW - Vaccines KW - Immunoassays KW - V 22350:Immunology KW - F 06905:Vaccines KW - Q1 08485:Species interactions: pests and control KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1323803451?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+and+Vaccine+Immunology&rft.atitle=Optimization+of+the+Cutoff+Value+for+a+Commercial+Anti-Dengue+Virus+IgG+Immunoassay&rft.au=Marrero-Santos%2C+Karla+M%3BBeltran%2C+Manuela%3BCarrion-Lebron%2C+Jessica%3BSanchez-Vegas%2C+Carolina%3BHamer%2C+Davidson+H%3BBarnett%2C+Elizabeth+D%3BSantiago%2C+Luis+M%3BHunsperger%2C+Elizabeth+A&rft.aulast=Marrero-Santos&rft.aufirst=Karla&rft.date=2013-03-01&rft.volume=20&rft.issue=3&rft.spage=358&rft.isbn=&rft.btitle=&rft.title=Clinical+and+Vaccine+Immunology&rft.issn=15566811&rft_id=info:doi/10.1128%2FCVI.00429-12 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-04-01 N1 - Number of references - 18 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Antibodies; Endemic species; Specificity; Immunology; Disease control; ELISA; Vaccines; Vaccination; Immunoassays; Travel; Enzyme-linked immunosorbent assay; Dengue; Immunoglobulin G; Plaques; Yellow fever virus; USA, Massachusetts, Boston DO - http://dx.doi.org/10.1128/CVI.00429-12 ER - TY - JOUR T1 - Tropism and Infectivity of Influenza Virus, Including Highly Pathogenic Avian H5N1 Virus, in Ferret Tracheal Differentiated Primary Epithelial Cell Cultures AN - 1315617524; 17709927 AB - Tropism and adaptation of influenza viruses to new hosts is partly dependent on the distribution of the sialic acid (SA) receptors to which the viral hemagglutinin (HA) binds. Ferrets have been established as a valuable in vivo model of influenza virus pathogenesis and transmission because of similarities to humans in the distribution of HA receptors and in clinical signs of infection. In this study, we developed a ferret tracheal differentiated primary epithelial cell culture model that consisted of a layered epithelium structure with ciliated and nonciliated cells on its apical surface. We found that human-like ( alpha 2,6-linked) receptors predominated on ciliated cells, whereas avian-like ( alpha 2,3-linked) receptors, which were less abundant, were presented on nonciliated cells. When we compared the tropism and infectivity of three human (H1 and H3) and two avian (H1 and H5) influenza viruses, we observed that the human influenza viruses primarily infected ciliated cells and replicated efficiently, whereas a highly pathogenic avian H5N1 virus (A/Vietnam/1203/2004) replicated efficiently within nonciliated cells despite a low initial infection rate. Furthermore, compared to other influenza viruses tested, VN/1203 virus replicated more efficiently in cells isolated from the lower trachea and at a higher temperature (37 degree C) compared to a lower temperature (33 degree C). VN/1203 virus infection also induced higher levels of immune mediator genes and cell death, and virus was recovered from the basolateral side of the cell monolayer. This ferret tracheal differentiated primary epithelial cell culture system provides a valuable in vitro model for studying cellular tropism, infectivity, and the pathogenesis of influenza viruses. JF - Journal of Virology AU - Zeng, Hui AU - Goldsmith, Cynthia S AU - Maines, Taronna R AU - Belser, Jessica A AU - Gustin, Kortney M AU - Pekosz, Andrew AU - Zaki, Sherif R AU - Katz, Jacqueline M AU - Tumpey, Terrence M AD - Immunology and Pathogenesis Branch, Influenza Division, National Center for Immunization and Respiratory Disease, TerrenceM.Tumpey,tft9{at}cdc.gov. Y1 - 2013/03// PY - 2013 DA - Mar 2013 SP - 2597 EP - 2607 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 87 IS - 5 SN - 0022-538X, 0022-538X KW - Biotechnology and Bioengineering Abstracts; Virology & AIDS Abstracts KW - Temperature effects KW - Epithelial cells KW - Adaptations KW - Hemagglutinins KW - Tropism KW - Cell culture KW - Infection KW - Mustela putorius furo KW - Influenza KW - Cell death KW - Infectivity KW - Influenza virus KW - Epithelium KW - Trachea KW - Sialic acids KW - V 22410:Animal Diseases KW - W 30945:Fermentation & Cell Culture UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1315617524?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Virology&rft.atitle=Tropism+and+Infectivity+of+Influenza+Virus%2C+Including+Highly+Pathogenic+Avian+H5N1+Virus%2C+in+Ferret+Tracheal+Differentiated+Primary+Epithelial+Cell+Cultures&rft.au=Zeng%2C+Hui%3BGoldsmith%2C+Cynthia+S%3BMaines%2C+Taronna+R%3BBelser%2C+Jessica+A%3BGustin%2C+Kortney+M%3BPekosz%2C+Andrew%3BZaki%2C+Sherif+R%3BKatz%2C+Jacqueline+M%3BTumpey%2C+Terrence+M&rft.aulast=Zeng&rft.aufirst=Hui&rft.date=2013-03-01&rft.volume=87&rft.issue=5&rft.spage=2597&rft.isbn=&rft.btitle=&rft.title=Journal+of+Virology&rft.issn=0022538X&rft_id=info:doi/10.1128%2FJVI.02885-12 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-03-01 N1 - Number of references - 54 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Temperature effects; Epithelial cells; Adaptations; Hemagglutinins; Tropism; Cell culture; Infection; Influenza; Infectivity; Cell death; Epithelium; Trachea; Sialic acids; Mustela putorius furo; Influenza virus DO - http://dx.doi.org/10.1128/JVI.02885-12 ER - TY - JOUR T1 - Racial and ethnic differences in health status and health behavior among breast cancer survivors-Behavioral Risk Factor Surveillance System, 2009 AN - 1315612290; 17685162 AB - Purpose: Differences in health status and behavioral risk factors may explain racial/ethnic breast cancer disparities. We examined racial/ethnic differences in health status and behaviors among female breast cancer survivors compared to females without breast cancer. Methods: Using cross-sectional data from the 2009 Behavioral Risk Factor Surveillance System, a national state-based, random sample telephone survey, we explored differences in self-rated health, obesity and selected behaviors (physical activity, smoking, alcohol use, fruit, and vegetable consumption) among females aged 18 years and older, who reported a previous breast cancer diagnosis (survivors, n=10,035) and those who reported no breast cancer history (n=234,375) by race/ethnicity. Adjusted prevalences of health status and behaviors, accounting for sociodemographics, comorbidities and health care access, were estimated by race/ethnicity. Results: Compared to all other racial/ethnic groups, more white females reported heavy alcohol consumption and more black females reported obesity regardless of their breast cancer status. Among breast cancer survivors, more whites (33.7 %) were former smokers compared to blacks (24.5 %), "others" (20.5 %), and Hispanics (16.2 %) (p=0.001). Racial/ethnic differences in obesity also varied by reported time since diagnosis (p value=0.018). Among long-term survivors (diagnosed >5 years before interview), more black survivors (34.8 %) reported obesity compared to white survivors (23.0 %). Also, among "other" race survivors, long-term survivors (22.0 %) reported more obesity than survivors diagnosed less than 5 years before interview (7.8 %). Conclusions: These findings suggest opportunities to increase health behaviors and reduce racial disparities among breast cancer survivors. Implications for Cancer Survivors: Engaging in healthy behaviors can play a significant role in enhancing health outcomes and quality of life of breast cancer survivors. More research is needed to better understand racial differences in obesity, smoking and alcohol consumption in order to develop effective, culturally appropriate interventions to promote a healthy lifestyle after a breast cancer diagnosis. JF - Journal of Cancer Survivorship AU - White, Arica AU - Pollack, Lori A AU - Smith, Judith Lee AU - Thompson, Trevor AU - Underwood, JMichael AU - Fairley, Temeika AD - Centers for Disease Control and Prevention, Division of Cancer Prevention and Control, Epidemiology and Applied Research Branch, 4770 Buford Hwy NE, Mailstop K-55, Atlanta, GA, 30341, USA, awhite5@cdc.gov Y1 - 2013/03// PY - 2013 DA - Mar 2013 SP - 93 EP - 103 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 7 IS - 1 SN - 1932-2259, 1932-2259 KW - Health & Safety Science Abstracts; Risk Abstracts KW - Fruits KW - Alcohol KW - Obesity KW - Physical activity KW - Intervention KW - Morbidity KW - Cancer KW - Health risks KW - Smoking KW - Health care KW - Behavior KW - Risk factors KW - Breast cancer KW - Ethnic groups KW - Quality of life KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1315612290?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Cancer+Survivorship&rft.atitle=Racial+and+ethnic+differences+in+health+status+and+health+behavior+among+breast+cancer+survivors-Behavioral+Risk+Factor+Surveillance+System%2C+2009&rft.au=White%2C+Arica%3BPollack%2C+Lori+A%3BSmith%2C+Judith+Lee%3BThompson%2C+Trevor%3BUnderwood%2C+JMichael%3BFairley%2C+Temeika&rft.aulast=White&rft.aufirst=Arica&rft.date=2013-03-01&rft.volume=7&rft.issue=1&rft.spage=93&rft.isbn=&rft.btitle=&rft.title=Journal+of+Cancer+Survivorship&rft.issn=19322259&rft_id=info:doi/10.1007%2Fs11764-012-0248-4 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-03-01 N1 - Number of references - 42 N1 - Last updated - 2013-12-04 N1 - SubjectsTermNotLitGenreText - Obesity; Alcohol; Fruits; Physical activity; Intervention; Cancer; Morbidity; Smoking; Health risks; Behavior; Health care; Risk factors; Breast cancer; Ethnic groups; Quality of life DO - http://dx.doi.org/10.1007/s11764-012-0248-4 ER - TY - JOUR T1 - Toxicological analysis of limonene reaction products using an in vitro exposure system. AN - 1314336565; 23220291 AB - Epidemiological investigations suggest a link between exposure to indoor air chemicals and adverse health effects. Consumer products contain reactive chemicals which can form secondary pollutants which may contribute to these effects. The reaction of limonene and ozone is a well characterized example of this type of indoor air chemistry. The studies described here characterize an in vitro model using an epithelial cell line (A549) or differentiated epithelial tissue (MucilAir™). The model is used to investigate adverse effects following exposure to combinations of limonene and ozone. In A549 cells, exposure to both the parent compounds and reaction products resulted in alterations in inflammatory cytokine production. A one hour exposure to limonene+ozone resulted in decreased proliferation when compared to cells exposed to limonene alone. Repeated dose exposures of limonene or limonene+ozone were conducted on MucilAir™ tissue. No change in proliferation was observed but increases in cytokine production were observed for both the parent compounds and reaction products. Factors such as exposure duration, chemical concentration, and sampling time point were identified to influence result outcome. These findings suggest that exposure to reaction products may produce more severe effects compared to the parent compound. Published by Elsevier Ltd. JF - Toxicology in vitro : an international journal published in association with BIBRA AU - Anderson, Stacey E AU - Khurshid, Shahana S AU - Meade, B Jean AU - Lukomska, Ewa AU - Wells, J R AD - Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, United States. sanderson4@cdc.gov Y1 - 2013/03// PY - 2013 DA - March 2013 SP - 721 EP - 730 VL - 27 IS - 2 KW - Air Pollutants KW - 0 KW - Cyclohexenes KW - Cytokines KW - Terpenes KW - Ozone KW - 66H7ZZK23N KW - limonene KW - 9MC3I34447 KW - Index Medicus KW - Cell Proliferation -- drug effects KW - Respiratory Mucosa -- metabolism KW - Air Pollution, Indoor KW - Humans KW - In Vitro Techniques KW - Respiratory Mucosa -- drug effects KW - Cytokines -- metabolism KW - Cell Line, Tumor KW - Terpenes -- toxicity KW - Terpenes -- chemistry KW - Cyclohexenes -- toxicity KW - Cyclohexenes -- chemistry KW - Air Pollutants -- toxicity KW - Ozone -- chemistry KW - Air Pollutants -- chemistry KW - Ozone -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1314336565?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+in+vitro+%3A+an+international+journal+published+in+association+with+BIBRA&rft.atitle=Toxicological+analysis+of+limonene+reaction+products+using+an+in+vitro+exposure+system.&rft.au=Anderson%2C+Stacey+E%3BKhurshid%2C+Shahana+S%3BMeade%2C+B+Jean%3BLukomska%2C+Ewa%3BWells%2C+J+R&rft.aulast=Anderson&rft.aufirst=Stacey&rft.date=2013-03-01&rft.volume=27&rft.issue=2&rft.spage=721&rft.isbn=&rft.btitle=&rft.title=Toxicology+in+vitro+%3A+an+international+journal+published+in+association+with+BIBRA&rft.issn=1879-3177&rft_id=info:doi/10.1016%2Fj.tiv.2012.11.017 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2013-08-20 N1 - Date created - 2013-02-28 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Inhal Toxicol. 2003 Oct;15(12):1191-207 [14515222] Am J Public Health. 2002 Sep;92(9):1430-40 [12197969] J Allergy Clin Immunol. 1997 Jan;99(1 Pt 1):65-76 [9003213] J Allergy Clin Immunol. 2005 Apr;115(4):771-8 [15805997] Inhal Toxicol. 2005 Dec 1;17(13):775-87 [16195213] Environ Sci Technol. 2005 Sep 15;39(18):6937-43 [16201614] Indoor Air. 2004;14 Suppl 7:184-94 [15330786] Indoor Air. 2006 Jun;16(3):179-91 [16683937] Korean J Intern Med. 2007 Mar;22(1):8-12 [17427638] Int Arch Occup Environ Health. 2007 Aug;80(8):711-9 [17357796] Toxicol In Vitro. 2008 Mar;22(2):359-66 [17993253] Toxicol In Vitro. 2008 Jun;22(4):1107-14 [18395406] Exp Toxicol Pathol. 2008 Jun;60(2-3):185-93 [18514500] Toxicol In Vitro. 2008 Sep;22(6):1419-31 [18603401] Exp Toxicol Pathol. 2009 Jan;61(1):33-9 [18650076] Environ Sci Technol. 2009 May 15;43(10):3561-8 [19544855] Toxicol Appl Pharmacol. 2010 Jan 1;242(1):100-8 [19800902] Toxicol Lett. 2010 Jun 2;195(2-3):99-105 [20226236] Toxicol Lett. 2010 Jun 16;196(1):33-41 [20362040] Toxicol Sci. 2010 Jun;115(2):453-61 [20200221] Eur Respir J. 2010 Dec;36(6):1270-6 [20351028] Eur J Pharm Biopharm. 2011 Apr;77(3):398-406 [21056660] J Water Health. 2011 Sep;9(3):586-96 [21976205] Respiration. 2012;83(1):36-44 [21912093] Toxicol Lett. 2012 Mar 7;209(2):166-72 [22212438] Toxicol Lett. 2012 Jun 1;211(2):159-63 [22484645] PLoS One. 2012;7(7):e39817 [22802943] Chest. 2012 Jul;142(1):86-93 [22345378] Am J Respir Crit Care Med. 1999 Nov;160(5 Pt 2):S38-43 [10556168] Immunopharmacology. 2000 Mar;46(3):253-61 [10741905] Toxicol In Vitro. 2001 Dec;15(6):631-4 [11698162] Exp Toxicol Pathol. 2001 Oct;53(5):373-86 [11817107] Toxicol Lett. 2003 Jul 20;143(2):109-14 [12749814] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.tiv.2012.11.017 ER - TY - JOUR T1 - Pre-Travel Health Care of Immigrants Returning Home to Visit Friends and Relatives AN - 1647006753; 21172027 AB - Immigrants returning home to visit friends and relatives (VFR travelers) are at higher risk of travel-associated illness than other international travelers. We evaluated 3,707 VFR and 17,507 non-VFR travelers seen for pre-travel consultation in Global TravEpiNet during 2009-2011; all were traveling to resource-poor destinations. VFR travelers more commonly visited urban destinations than non-VFR travelers (42% versus 30%, P < 0.0001); 54% of VFR travelers were female, and 18% of VFR travelers were under 6 years old. VFR travelers sought health advice closer to their departure than non-VFR travelers (median days before departure was 17 versus 26, P < 0.0001). In multivariable analysis, being a VFR traveler was an independent predictor of declining a recommended vaccine. Missed opportunities for vaccination could be addressed by improving the timing of pre-travel health care and increasing the acceptance of vaccines. Making pre-travel health care available in primary care settings may be one step to this goal. JF - American Journal of Tropical Medicine and Hygiene AU - LaRocque, Regina C AU - Deshpande, Bhushan R AU - Rao, Sowmya R AU - Brunette, Gary W AU - Sotir, Mark J AU - Jentes, Emily S AU - Ryan, Edward T AD - Travelers' Advice and Immunization Center, Massachusetts General Hospital and Department of Medicine, Harvard Medical School, 55 Fruit Street, Boston, MA 02114; Harvard Medical School, Boston, Massachusetts; Tufts University, Medford, Massachusetts; Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, Massachusetts; Center for Health Quality, Outcomes, and Economics Research, Bedford Veterans Affairs Medical Center, Bedford, Massachusetts; Division of Global Migration and Quarantine, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, rclarocque@partners.org Y1 - 2013/02// PY - 2013 DA - February 2013 SP - 376 EP - 380 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 88 IS - 2 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Risk Abstracts; Sustainability Science Abstracts KW - Health care KW - Risk factors KW - Navigation behavior KW - Immigrants KW - Vaccines KW - K 03490:Miscellaneous KW - M3 1010:Issues in Sustainable Development KW - J 02350:Immunology KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1647006753?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Pre-Travel+Health+Care+of+Immigrants+Returning+Home+to+Visit+Friends+and+Relatives&rft.au=LaRocque%2C+Regina+C%3BDeshpande%2C+Bhushan+R%3BRao%2C+Sowmya+R%3BBrunette%2C+Gary+W%3BSotir%2C+Mark+J%3BJentes%2C+Emily+S%3BRyan%2C+Edward+T&rft.aulast=LaRocque&rft.aufirst=Regina&rft.date=2013-02-01&rft.volume=88&rft.issue=2&rft.spage=376&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.2012.12-0460 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Risk factors; Navigation behavior; Immigrants; Vaccines; Health care DO - http://dx.doi.org/10.4269/ajtmh.2012.12-0460 ER - TY - JOUR T1 - Do Zero-Cost Workers' Compensation Medical Claims Really Have Zero Costs?: The Impact of Workplace Injury on Group Health Insurance Utilization and Costs AN - 1512335024; 19444019 AB - Objective: Previous research suggests that non-workers' compensation (WC) insurance systems, such as group health insurance (GHI), Medicare, or Medicaid, at least partially cover work-related injury and illness costs. This study further examined GHI utilization and costs. Methods: Using two-part model, we compared those outcomes immediately after injuries for which accepted WC medical claims made zero or positive medical payments. Results: Controlling for pre-injury GHI utilization and costs and other covariates, our results indicated that post-injury GHI utilization and costs increased regardless of whether a WC medical claim was zero or positive. The increases were highest for zero-cost WC medical claims. Conclusion: Our national estimates showed that zero-cost WC medical claims alone could cost the GHI $212 million per year. JF - Journal of Occupational and Environmental Medicine AU - Asfaw, Abay AU - Rosa, Roger AU - Mao, Rebecca AD - Office of the Director, Centers for Disease Control and Prevention-National Institute for Occupational Safety and Health, 395 E St, SW, Washington, DC 20201, hqp0@cdc.gov PY - 2013 SP - 1394 EP - 1400 PB - Williams & Wilkins, 351 W. Camden St. Baltimore MD 21201 United States VL - 55 IS - 12 SN - 1076-2752, 1076-2752 KW - Health & Safety Science Abstracts KW - Workers' compensation KW - Injuries KW - Socioeconomics KW - Insurance KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1512335024?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Do+Zero-Cost+Workers%27+Compensation+Medical+Claims+Really+Have+Zero+Costs%3F%3A+The+Impact+of+Workplace+Injury+on+Group+Health+Insurance+Utilization+and+Costs&rft.au=Asfaw%2C+Abay%3BRosa%2C+Roger%3BMao%2C+Rebecca&rft.aulast=Asfaw&rft.aufirst=Abay&rft.date=2013-02-01&rft.volume=55&rft.issue=12&rft.spage=1394&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0000000000000030 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-04-01 N1 - Last updated - 2015-12-23 N1 - SubjectsTermNotLitGenreText - Workers' compensation; Injuries; Socioeconomics; Insurance DO - http://dx.doi.org/10.1097/JOM.0000000000000030 ER - TY - JOUR T1 - Asthma in Health Care Workers: 2008 and 2010 Behavioral Risk Factor Surveillance System Asthma Call-Back Survey AN - 1512334614; 19444029 AB - Objective: To estimate the prevalence of current asthma and the proportion of asthma that is work-related among health care and non-health care workers. Methods: We used 2008 and 2010 Behavioral Risk Factor Surveillance System High Risk Health Care Worker Module and Asthma Call-Back Survey data collected in 35 states and thc District of Columbia to estimate prevalence ratios (PRs). Results: Significantly more health care workers/volunteers than non-health care workers volunteers with current asthma had asthma attacks (PR = 1.23; 95% confidence interval = 1.03 to 1.46) and asthma symptoms within the past year (PR = 1.07; 95% confidence interval = 1.00 to 1.14). There was no significant difference in the proportion of health care and non-health care workers/volunteers diagnosed with current asthma or work-related asthma. Conclusions: The results of this study are Consistent with previous research showing that health care workers with asthma have higher proportions of asthma attacks than non-health care workers. JF - Journal of Occupational and Environmental Medicine AU - White, Gretchen E AU - Mazurek, Jacek M AU - Moorman, Jeanne E AD - National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WVa, ipb8@cdc.gov PY - 2013 SP - 1463 EP - 1468 PB - Williams & Wilkins, 351 W. Camden St. Baltimore MD 21201 United States VL - 55 IS - 12 SN - 1076-2752, 1076-2752 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Health care KW - Risk factors KW - Asthma KW - Risk taking KW - Respiratory diseases KW - Medical personnel KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1512334614?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Asthma+in+Health+Care+Workers%3A+2008+and+2010+Behavioral+Risk+Factor+Surveillance+System+Asthma+Call-Back+Survey&rft.au=White%2C+Gretchen+E%3BMazurek%2C+Jacek+M%3BMoorman%2C+Jeanne+E&rft.aulast=White&rft.aufirst=Gretchen&rft.date=2013-02-01&rft.volume=55&rft.issue=12&rft.spage=1463&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0000000000000006 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-04-01 N1 - Last updated - 2015-12-23 N1 - SubjectsTermNotLitGenreText - Health care; Risk factors; Risk taking; Asthma; Respiratory diseases; Medical personnel DO - http://dx.doi.org/10.1097/JOM.0000000000000006 ER - TY - JOUR T1 - Sexual behaviour and desire to discuss mental health as reported by HIV-infected men who have sex with men AN - 1430849343; 18439185 AB - We assessed sexually transmitted infection risk behaviours and desire to discuss mental health, as reported by 426 HIV-infected men who have sex with men receiving HIV care in eight urban clinics. Most of these patients (90%) had begun HIV care >1 year ago. In the past year, 74% had multiple sexual partners, 75% engaged in anal intercourse, 48% had >1 HIV-uninfected partner and 82% used illegal psychoactive drugs. Among those reporting anal intercourse, approximately 61 % reported using a condom during the most recent episode. Among all patients, 70% wanted to talk with their clinicians about how they felt mentally or emotionally. Using a two-tailed chi-squared test, we found that patients who engaged in unprotected receptive anal sex were more likely to want such a conversation than those who did not (80% versus 62%, P < 0.01); and those who engaged in unprotected insertive anal sex were also more likely to want such a conversation (81 % versus 63%, P < 0.01). The findings highlight the prevalence of risky sexual behaviour and of mental health concerns in the participating patient population. Patients reporting risky sexual behaviour were more likely to want to discuss how they felt mentally or emotionally than those not reporting such behaviour. JF - International Journal of STD & AIDS AU - Safran, MA AU - Hoover, K W AU - Tao, G AU - Butler, MO AD - Centers for Disease Control and Prevention, Mail Stop E-44, 1600 Clifton Road, Atlanta, GA, 30333, USA, MSafran@cdc.gov Y1 - 2013/02// PY - 2013 DA - Feb 2013 SP - 93 EP - 99 VL - 24 IS - 2 SN - 0956-4624, 0956-4624 KW - Health & Safety Science Abstracts; Risk Abstracts; Virology & AIDS Abstracts KW - Emotions KW - Acquired immune deficiency syndrome KW - anal sex KW - Homosexuality KW - Anal sex KW - Infection KW - Sexual behavior KW - Condoms KW - Sexual partners KW - Mental disorders KW - Infectious diseases KW - Human immunodeficiency virus KW - Drugs KW - Sexually transmitted diseases KW - Sex KW - V 22360:AIDS and HIV KW - H 4000:Food and Drugs KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1430849343?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+STD+%26+AIDS&rft.atitle=Sexual+behaviour+and+desire+to+discuss+mental+health+as+reported+by+HIV-infected+men+who+have+sex+with+men&rft.au=Safran%2C+MA%3BHoover%2C+K+W%3BTao%2C+G%3BButler%2C+MO&rft.aulast=Safran&rft.aufirst=MA&rft.date=2013-02-01&rft.volume=24&rft.issue=2&rft.spage=93&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+STD+%26+AIDS&rft.issn=09564624&rft_id=info:doi/10.1177%2F0956462412472307 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-09-01 N1 - Last updated - 2013-12-04 N1 - SubjectsTermNotLitGenreText - Sexual partners; Condoms; Emotions; Mental disorders; anal sex; Infection; Drugs; Sexual behavior; Sex; Acquired immune deficiency syndrome; Infectious diseases; Human immunodeficiency virus; Anal sex; Homosexuality; Sexually transmitted diseases DO - http://dx.doi.org/10.1177/0956462412472307 ER - TY - JOUR T1 - Foodborne outbreaks of shigellosis in the USA, 1998-2008 AN - 1367491979; 18084066 AB - We examined reported outbreaks of foodborne shigellosis in the USA from 1998 to 2008 and summarized demographic and epidemiological characteristics of 120 confirmed outbreaks resulting in 6208 illnesses. Most reported foodborne shigellosis outbreaks (n = 70, 58%) and outbreak-associated illnesses (n = 3383, 54%) were restaurant-associated. The largest outbreaks were associated with commercially prepared foods distributed in multiple states and foods prepared in institutional settings. Foods commonly consumed raw were implicated in 29 (24%) outbreaks and infected food handlers in 28 (23%) outbreaks. Most outbreaks (n = 86, 72%) were caused by Shigella sonnei. Targeted efforts to reduce contamination during food handling at multiple points in the food processing and distribution system, including food preparation in restaurants and institutional settings, could prevent many foodborne disease outbreaks and outbreak-related illnesses including those due to Shigella. JF - Epidemiology and Infection AU - Nygren, B L AU - Schilling, KA AU - Blanton, E M AU - Silk, B J AU - Cole, D J AU - Mintz, ED AD - Division of Foodborne, Waterborne, and Environmental Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA, ghz8@cdc.gov Y1 - 2013/02// PY - 2013 DA - Feb 2013 SP - 233 EP - 241 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 141 IS - 2 SN - 0950-2688, 0950-2688 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Health & Safety Science Abstracts KW - Demography KW - USA KW - Food technology KW - Shigella sonnei KW - Contamination KW - Epidemiology KW - Handling KW - Shigella KW - Outbreaks KW - Food contamination KW - Food-borne diseases KW - Q1 08484:Species interactions: parasites and diseases KW - H 12000:Epidemiology and Public Health KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1367491979?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Foodborne+outbreaks+of+shigellosis+in+the+USA%2C+1998-2008&rft.au=Nygren%2C+B+L%3BSchilling%2C+KA%3BBlanton%2C+E+M%3BSilk%2C+B+J%3BCole%2C+D+J%3BMintz%2C+ED&rft.aulast=Nygren&rft.aufirst=B&rft.date=2013-02-01&rft.volume=141&rft.issue=2&rft.spage=233&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268812000222 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-06-01 N1 - Number of references - 30 N1 - Last updated - 2014-12-11 N1 - SubjectsTermNotLitGenreText - Food technology; Epidemiology; Contamination; Handling; Demography; Outbreaks; Food contamination; Food-borne diseases; Shigella sonnei; Shigella; USA DO - http://dx.doi.org/10.1017/S0950268812000222 ER - TY - JOUR T1 - Gynaecologic cancer symptom awareness, concern and care seeking among US women: a multi-site qualitative study AN - 1364765077; 201308786 AB - Background. With limited screening options, early detection of gynaecologic cancers can depend on women recognizing the potential significance of symptoms and seeking care. Objective. We investigated women's concern about symptoms that might be related to gynaecologic cancers, the underlying conditions they associated with symptoms and their actual and hypothetical response to symptoms. Methods. Fifteen focus groups with women aged 40-60 years were conducted in Chicago, Los Angeles, Miami and New York City. Participants were given an untitled list of symptoms that could indicate various gynaecologic cancers and asked if any would concern them, what could cause each and what they would do if they experienced any of them. Results. Overall, participants expressed greater concern about symptoms clearly gynaecologic in nature than other symptoms. Participants generally did not associate symptoms with any form of cancer. Some women who had experienced symptoms reported waiting an extended period before seeking care or not seeking care at all. The belief that a symptom indicated a benign condition was the most common reason given for delaying or foregoing care seeking. Strategies participants reported using to supplement or replace consultations with health care providers included Internet research and self-care. Conclusion. Raising awareness of symptoms that can indicate gynaecologic cancers may lead to earlier detection and improved survival. In particular, women should be informed that gynaecologic cancers can cause symptoms that may not seem related to the reproductive organs (e.g. back pain) and that unusual vaginal bleeding should prompt them to seek care immediately. Adapted from the source document. JF - Family Practice AU - Cooper, Crystale Purvis AU - Polonec, Lindsey AU - Stewart, Sherri L AU - Gelb, Cynthia A AD - Soltera Center for Cancer Prevention and Control Tucson, Arizona, USA Y1 - 2013/02// PY - 2013 DA - February 2013 SP - 96 EP - 104 PB - Oxford University Press VL - 30 IS - 1 SN - 0263-2136, 0263-2136 KW - Neoplasms women's health early detection of cancer qualitative research focus groups KW - Symptoms KW - Selfcare KW - Consultation KW - Women KW - Biological organs KW - Cancer KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1364765077?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Family+Practice&rft.atitle=Gynaecologic+cancer+symptom+awareness%2C+concern+and+care+seeking+among+US+women%3A+a+multi-site+qualitative+study&rft.au=Cooper%2C+Crystale+Purvis%3BPolonec%2C+Lindsey%3BStewart%2C+Sherri+L%3BGelb%2C+Cynthia+A&rft.aulast=Cooper&rft.aufirst=Crystale&rft.date=2013-02-01&rft.volume=30&rft.issue=1&rft.spage=96&rft.isbn=&rft.btitle=&rft.title=Family+Practice&rft.issn=02632136&rft_id=info:doi/10.1093%2Ffampra%2Fcms040 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2013-06-01 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Symptoms; Cancer; Women; Biological organs; Consultation; Selfcare DO - http://dx.doi.org/10.1093/fampra/cms040 ER - TY - JOUR T1 - Predicting Temporal Trends in Sickness Absence Rates for Civil Service Employees of a Federal Public Health Agency AN - 1323816109; 17806663 AB - Objective: To determine whether trends of sickness in employees at a federal agency are predictable, and whether the variance was minimal enough to detect unusual levels of employee illness for further investigation. Methods: Ten years of absenteeism data from an attendance system were analyzed for rates of sickness absence. Specifically, week of year and day of week were used to describe temporal trends. Results: This study evaluates the predictability in temporal absence trends due to sickness among employees at a federal agency. Trends follow regular patterns during a given year that correspond to seasonal illnesses. Temporal trends in sick leave have been proven to be very predictable. Conclusion: The minimal variance allows the detection of sick leave anomalies that may be ascribable to specific causes, allowing the business or agency to follow-up and develop interventions. JF - Journal of Occupational and Environmental Medicine AU - Spears AU - McNeil, C AU - Warnock, E AU - Trapp, J AU - Oyinloye, O AU - Whitehurst, V AU - Decker, K C AU - Chapman, S AU - Campbell, M AU - Meechan, P AD - US Public Health Service, Occupational Health and Preventive Services, Office of Safety, Health, and Environment, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, MS F-05, Atlanta, GA 30333, USA, ava3@cdc.gov PY - 2013 SP - 179 EP - 190 VL - 55 IS - 2 SN - 1076-2752, 1076-2752 KW - Health & Safety Science Abstracts KW - Sulfur dioxide KW - Intervention KW - Seasonal variations KW - Public health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1323816109?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Predicting+Temporal+Trends+in+Sickness+Absence+Rates+for+Civil+Service+Employees+of+a+Federal+Public+Health+Agency&rft.au=Spears%3BMcNeil%2C+C%3BWarnock%2C+E%3BTrapp%2C+J%3BOyinloye%2C+O%3BWhitehurst%2C+V%3BDecker%2C+K+C%3BChapman%2C+S%3BCampbell%2C+M%3BMeechan%2C+P&rft.aulast=Spears&rft.aufirst=&rft.date=2013-02-01&rft.volume=55&rft.issue=2&rft.spage=179&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e3182717eb5 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-04-01 N1 - Last updated - 2015-12-23 N1 - SubjectsTermNotLitGenreText - Sulfur dioxide; Intervention; Seasonal variations; Public health DO - http://dx.doi.org/10.1097/JOM.0b013e3182717eb5 ER - TY - JOUR T1 - Nanotechnology: Toxicologic Pathology AN - 1323801066; 17782859 AB - Nanotechnology involves technology, science, and engineering in dimensions less than 100 nm. A virtually infinite number of potential nanoscale products can be produced from many different molecules and their combinations. The exponentially increasing number of nanoscale products will solve critical needs in engineering, science, and medicine. However, the virtually infinite number of potential nanotechnology products is a challenge for toxicologic pathologists. Because of their size, nanoparticulates can have therapeutic and toxic effects distinct from micron-sized particulates of the same composition. In the nanoscale, distinct intercellular and intracellular translocation pathways may provide a different distribution than that obtained by micron-sized particulates. Nanoparticulates interact with subcellular structures including microtubules, actin filaments, centrosomes, and chromatin; interactions that may be facilitated in the nanoscale. Features that distinguish nanoparticulates from fine particulates include increased surface area per unit mass and quantum effects. In addition, some nanotechnology products, including the fullerenes, have a novel and reactive surface. Augmented microscopic procedures including enhanced dark-field imaging, immunofluorescence, field-emission scanning electron microscopy, transmission electron microscopy, and confocal microscopy are useful when evaluating nanoparticulate Toxicologic Pathology. Thus, the pathology assessment is facilitated by understanding the unique features at the nanoscale and the tools that can assist in evaluating nanotoxicology studies. JF - Toxicologic Pathology AU - Hubbs, Ann F AU - Sargent, Linda M AU - Porter, Dale W AU - Sager, Tina M AU - Chen, Bean T AU - Frazer, David G AU - Castranova, Vincent AU - Sriram, Krishnan AU - Nurkiewicz, Timothy R AU - Reynolds, Steven H AU - Battelli, Lori A AU - Schwegler-Berry, Diane AU - McKinney, Walter AU - Fluharty, Kara L AU - Mercer, Robert R AD - Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA, ahubbs@cdc.gov Y1 - 2013/02// PY - 2013 DA - February 2013 SP - 395 EP - 409 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU United Kingdom VL - 41 IS - 2 SN - 0192-6233, 0192-6233 KW - Toxicology Abstracts KW - Toxicologic Pathology KW - mechanisms of toxicity KW - microscopy techniques KW - pharmaceutical development/products KW - risk identification KW - safety assessment KW - other. KW - Scanning electron microscopy KW - Microtubules KW - Chromatin KW - Surface area KW - Transmission electron microscopy KW - Immunofluorescence KW - imaging KW - Fullerenes KW - Centrosomes KW - Confocal microscopy KW - Actin KW - Translocation KW - Filaments KW - nanotechnology KW - X 24490:Other UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1323801066?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicologic+Pathology&rft.atitle=Nanotechnology%3A+Toxicologic+Pathology&rft.au=Hubbs%2C+Ann+F%3BSargent%2C+Linda+M%3BPorter%2C+Dale+W%3BSager%2C+Tina+M%3BChen%2C+Bean+T%3BFrazer%2C+David+G%3BCastranova%2C+Vincent%3BSriram%2C+Krishnan%3BNurkiewicz%2C+Timothy+R%3BReynolds%2C+Steven+H%3BBattelli%2C+Lori+A%3BSchwegler-Berry%2C+Diane%3BMcKinney%2C+Walter%3BFluharty%2C+Kara+L%3BMercer%2C+Robert+R&rft.aulast=Hubbs&rft.aufirst=Ann&rft.date=2013-02-01&rft.volume=41&rft.issue=2&rft.spage=395&rft.isbn=&rft.btitle=&rft.title=Toxicologic+Pathology&rft.issn=01926233&rft_id=info:doi/10.1177%2F0192623312467403 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-04-01 N1 - Number of references - 206 N1 - Last updated - 2016-08-03 N1 - SubjectsTermNotLitGenreText - Scanning electron microscopy; Microtubules; Chromatin; Transmission electron microscopy; Surface area; Immunofluorescence; imaging; Fullerenes; Centrosomes; Confocal microscopy; Actin; Filaments; Translocation; nanotechnology DO - http://dx.doi.org/10.1177/0192623312467403 ER - TY - JOUR T1 - Sequential Triplex Real-Time PCR Assay for Detecting 21 Pneumococcal Capsular Serotypes That Account for a High Global Disease Burden AN - 1315617785; 17647990 AB - We developed and validated a real-time PCR assay consisting of 7 triplexed reactions to identify 11 individual serotypes plus 10 small serogroups representing the majority of disease-causing isolates of Streptococcus pneumoniae. This assay targets the 13 serotypes included within the 13-valent conjugate vaccine and 8 additional key serotypes or serogroups. Advantages over other serotyping assays are described. The assay will be expanded to 40 serotypes/serogroups. We will provide periodic updates at our protocol website. JF - Journal of Clinical Microbiology AU - Pimenta, Fabiana C AU - Roundtree, Alexis AU - Soysal, Ahmet AU - Bakir, Mustafa AU - Plessis, Mignon du AU - Wolter, Nicole AU - Gottberg, Anne von AU - McGee, Lesley AU - Gloria Carvalho, Maria da AU - Beall, Bernard AD - Respiratory Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, BernardBeall,bbeall{at}cdc.gov. Y1 - 2013/02// PY - 2013 DA - Feb 2013 SP - 647 EP - 652 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 51 IS - 2 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Streptococcus pneumoniae KW - Serotypes KW - Polymerase chain reaction KW - Serotyping KW - Vaccines KW - J 02300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1315617785?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Sequential+Triplex+Real-Time+PCR+Assay+for+Detecting+21+Pneumococcal+Capsular+Serotypes+That+Account+for+a+High+Global+Disease+Burden&rft.au=Pimenta%2C+Fabiana+C%3BRoundtree%2C+Alexis%3BSoysal%2C+Ahmet%3BBakir%2C+Mustafa%3BPlessis%2C+Mignon+du%3BWolter%2C+Nicole%3BGottberg%2C+Anne+von%3BMcGee%2C+Lesley%3BGloria+Carvalho%2C+Maria+da%3BBeall%2C+Bernard&rft.aulast=Pimenta&rft.aufirst=Fabiana&rft.date=2013-02-01&rft.volume=51&rft.issue=2&rft.spage=647&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.02927-12 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-03-01 N1 - Number of references - 22 N1 - Last updated - 2013-07-15 N1 - SubjectsTermNotLitGenreText - Serotypes; Serotyping; Polymerase chain reaction; Vaccines; Streptococcus pneumoniae DO - http://dx.doi.org/10.1128/JCM.02927-12 ER - TY - JOUR T1 - Factors Associated with Never Being Screened for Colorectal Cancer AN - 1315612003; 17670732 AB - Colorectal cancer (CRC) screening is underused in the United States, and non-adherence with screening recommendations is high in some populations. This study describes the characteristics of people who have never been screened for CRC. In addition, we use the health belief model to examine the constructs associated with screening behavior. We used data from the 2010 Behavioral Risk Factor Surveillance System (BRFSS) to create three study outcomes: people who have been screened for CRC and are up-to-date with current recommendations, people who have been screened but are not up-to-date, and people who have never been screened. We used multivariate logistic regression modeling to calculate predicted marginal estimates examining the associations between the screening outcomes and demographic and Health Belief Model (HBM) characteristics. Overall 29 % of respondents had never been screened for CRC. In the adjusted model, 36.6 % of US adults age 50-59 years and 29.1 % of US men reported never being screened for CRC. More Asian/Native Hawaiian/Pacific Islander, non-Hispanics (38.2 %) reported never being screened than members of other racial and ethnic groups. Nearly 37 % of people with less than a high school diploma reported never being screened. We found statistically significant differences among screening outcomes for all demographics and HBM constructs except could not see a doctor because of costs in the last 12 months, where approximately 29 % reported no CRC screening. New interventions should focus on those subpopulations that have never been screened for CRC. JF - Journal of Community Health AU - Stanley, Sandte L AU - King, Jessica B AU - Thomas, Cheryll C AU - Richardson, Lisa C AD - Centers for Disease Control and Prevention, 4770 Buford Hwy NE, MS K-52, Atlanta, GA, 30341, USA, lfr8@cdc.gov Y1 - 2013/02// PY - 2013 DA - Feb 2013 SP - 31 EP - 39 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 38 IS - 1 SN - 0094-5145, 0094-5145 KW - Health & Safety Science Abstracts; Risk Abstracts KW - Age KW - Colorectal carcinoma KW - Demography KW - Ethnic groups KW - Intervention KW - Risk factors KW - Subpopulations KW - USA KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1315612003?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Community+Health&rft.atitle=Factors+Associated+with+Never+Being+Screened+for+Colorectal+Cancer&rft.au=Stanley%2C+Sandte+L%3BKing%2C+Jessica+B%3BThomas%2C+Cheryll+C%3BRichardson%2C+Lisa+C&rft.aulast=Stanley&rft.aufirst=Sandte&rft.date=2013-02-01&rft.volume=38&rft.issue=1&rft.spage=31&rft.isbn=&rft.btitle=&rft.title=Journal+of+Community+Health&rft.issn=00945145&rft_id=info:doi/10.1007%2Fs10900-012-9600-x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-03-01 N1 - Number of references - 47 N1 - Last updated - 2013-05-06 N1 - SubjectsTermNotLitGenreText - Demography; Age; Risk factors; Subpopulations; Intervention; Colorectal carcinoma; Ethnic groups; USA DO - http://dx.doi.org/10.1007/s10900-012-9600-x ER - TY - JOUR T1 - Long-Term Immune Responses to Coxiella burnetii after Vaccination AN - 1291614938; 17647884 AB - Q fever is a zoonotic disease caused by infection with the bacterium Coxiella burnetii. Infection with C. burnetii results in humoral and cellular immune responses, both of which are thought to contribute to protection against subsequent infection. Whole-cell formalin-inactivated vaccines have also been shown to induce both humoral and cellular immunity and provide protection. Whether measurement of cellular or humoral immunity is a better indicator of immune protection is not known, and the duration of immunity induced by natural infection or vaccination is also poorly understood. To better understand the measurement and duration of C. burnetii immunity, 16 people vaccinated against Q fever (0.2 to 10.3 years before analysis) and 29 controls with a low risk of Q fever exposure were tested for immune responses to C. burnetii by an indirect fluorescent-antibody test (IFA) to measure circulating antibody and by a gamma interferon release assay (IGRA) to measure cellular immunity. Among vaccinated subjects, the IFA detected antibodies in 13/16, and the IGRA also detected positive responses in 13/16. All of the vaccinated subjects had a positive response in at least one of the assays, whereas 8/29 control subjects were positive in at least one assay. There was not a correlation between time since vaccination and responses in these assays. These results show that IFA and IGRA perform similarly in detection of C. burnetii immune responses and that Q fever vaccination establishes long-lived immune responses to C. burnetii. JF - Clinical and Vaccine Immunology AU - Kersh, Gilbert J AU - Fitzpatrick, Kelly A AU - Self, Joshua S AU - Biggerstaff, Brad J AU - Massung, Robert F AD - Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, GilbertJ.Kersh,gkersh{at}cdc.gov. Y1 - 2013/02// PY - 2013 DA - Feb 2013 SP - 129 EP - 133 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 20 IS - 2 SN - 1556-679X, 1556-679X KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Antibodies KW - Immune response KW - Immune response (humoral) KW - Immunity (cell-mediated) KW - Immunity (humoral) KW - Infection KW - Q fever KW - Risk factors KW - Vaccination KW - Vaccines KW - alpha -Interferon KW - gamma -Interferon KW - Coxiella burnetii KW - F 06905:Vaccines KW - J 02350:Immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1291614938?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+and+Vaccine+Immunology&rft.atitle=Long-Term+Immune+Responses+to+Coxiella+burnetii+after+Vaccination&rft.au=Kersh%2C+Gilbert+J%3BFitzpatrick%2C+Kelly+A%3BSelf%2C+Joshua+S%3BBiggerstaff%2C+Brad+J%3BMassung%2C+Robert+F&rft.aulast=Kersh&rft.aufirst=Gilbert&rft.date=2013-02-01&rft.volume=20&rft.issue=2&rft.spage=129&rft.isbn=&rft.btitle=&rft.title=Clinical+and+Vaccine+Immunology&rft.issn=1556679X&rft_id=info:doi/10.1128%2FCVI.00613-12 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-01 N1 - Number of references - 23 N1 - Last updated - 2013-03-22 N1 - SubjectsTermNotLitGenreText - Immunity (humoral); gamma -Interferon; Antibodies; Immunity (cell-mediated); Risk factors; alpha -Interferon; Vaccines; Immune response; Immune response (humoral); Infection; Vaccination; Q fever; Coxiella burnetii DO - http://dx.doi.org/10.1128/CVI.00613-12 ER - TY - CPAPER T1 - Pollen exposure and respiratory illness in a changing climate T2 - 93rd American Meteorological Society Annual Meeting (AMS 2013) AN - 1369229878; 6215624 JF - 93rd American Meteorological Society Annual Meeting (AMS 2013) AU - Saha, Shubhayu AU - Manangan, A AU - Luber, G Y1 - 2013/01/06/ PY - 2013 DA - 2013 Jan 06 KW - Respiration KW - Climate KW - Metabolism KW - Pollen UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1369229878?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=93rd+American+Meteorological+Society+Annual+Meeting+%28AMS+2013%29&rft.atitle=Pollen+exposure+and+respiratory+illness+in+a+changing+climate&rft.au=Saha%2C+Shubhayu%3BManangan%2C+A%3BLuber%2C+G&rft.aulast=Saha&rft.aufirst=Shubhayu&rft.date=2013-01-06&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=93rd+American+Meteorological+Society+Annual+Meeting+%28AMS+2013%29&rft.issn=&rft_id=info:doi/ L2 - https://ams.confex.com/ams/93Annual/webprogram/meeting.html# LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-05-31 N1 - Last updated - 2013-06-19 ER - TY - JOUR T1 - Overview of Risk Management for Engineered Nanomaterials AN - 1705071347; PQ0001813364 AB - To protect the nanomaterial workforce, a precautionary risk management approach is warranted and given the newness of ENMs and emergence of nanotechnology, a naturalistic view of risk management is useful. This is achieved by identifying and managing risks which include recognition of hazards, assessing exposures, characterizing actual risk, and implementing measures to control those risks. Following traditional risk management models for nanomaterials is challenging because of uncertainties about the nature of hazards, issues in exposure assessment, questions about appropriate control methods, and lack of occupational exposure limits (OELs) or nano-specific regulations. The precautionary approach entails minimizing exposures by using engineering controls and personal protective equipment (PPE). Generally, risk management utilizes the hierarchy of controls. Ideally, risk management for nanomaterials should be part of an enterprise-wide risk management program or system and this should include both risk control and a medical surveillance program that assesses the frequency of adverse effects among groups of workers exposed to nanomaterials. JF - Journal of Physics: Conference Series AU - Schulte, P A AU - Geraci, C L AU - Hodson, L L AU - Zumwalde, R D AU - Kuempel, E D AU - Murashov, V AU - Martinez, K F AU - Heidel, D S AD - National Institute for Occupational Safety and Heath 4676 Columbia Parkway, MS-C14 Cincinnati, OH 45226, PSchulte@cdc.gov Y1 - 2013///0, PY - 2013 DA - 0, 2013 SP - 1 EP - 10 PB - Institute of Physics Publishing Inc., The Public Ledger Building, Suite 929 Philadelphia PA 19106 United States VL - 429 SN - 1742-6588, 1742-6588 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Risk assessment KW - Risk management KW - Conferences KW - Protective equipment KW - Occupational exposure KW - Side effects KW - Nanotechnology KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1705071347?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Physics%3A+Conference+Series&rft.atitle=Overview+of+Risk+Management+for+Engineered+Nanomaterials&rft.au=Schulte%2C+P+A%3BGeraci%2C+C+L%3BHodson%2C+L+L%3BZumwalde%2C+R+D%3BKuempel%2C+E+D%3BMurashov%2C+V%3BMartinez%2C+K+F%3BHeidel%2C+D+S&rft.aulast=Schulte&rft.aufirst=P&rft.date=2013-01-01&rft.volume=429&rft.issue=&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Journal+of+Physics%3A+Conference+Series&rft.issn=17426588&rft_id=info:doi/10.1088%2F1742-6596%2F429%2F1%2F012062 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-08-01 N1 - Last updated - 2016-02-04 N1 - SubjectsTermNotLitGenreText - Risk assessment; Risk management; Conferences; Protective equipment; Side effects; Occupational exposure; Nanotechnology DO - http://dx.doi.org/10.1088/1742-6596/429/1/012062 ER - TY - JOUR T1 - What are the most sensitive and specific sign and symptom combinations for influenza in patients hospitalized with acute respiratory illness? Results from western Kenya, January 2007-July 2010 AN - 1705062317; PQ0001811195 AB - Influenza causes severe illness and deaths, and global surveillance systems use different clinical case definitions to identify patients for diagnostic testing. We used data collected during January 2007-July 2010 at hospital-based influenza surveillance sites in western Kenya to calculate sensitivity, specificity, positive predictive value, and negative predictive value for eight clinical sign/symptom combinations in hospitalized patients with acute respiratory illnesses, including severe acute respiratory illness (SARI) (persons aged 2-59 months: cough or difficulty breathing with an elevated respiratory rate or a danger sign; persons aged 5 years: temperature 38 degree C, difficulty breathing, and cough or sore throat) and influenza-like illness (ILI) (all ages: temperature 38 degree C and cough or sore throat). Overall, 4800 persons aged 2 months were tested for influenza; 416 (9%) had laboratory-confirmed influenza infections. The symptom combination of cough with fever (subjective or measured 38 degree C) had high sensitivity [87.0%, 95% confidence interval (CI) 83.3-88.9], and ILI had high specificity (70.0%, 95% CI 68.6-71.3). The case definition combining cough and any fever is a simple, sensitive case definition for influenza in hospitalized persons of all age groups, whereas the ILI case definition is the most specific. The SARI case definition did not maximize sensitivity or specificity. JF - Epidemiology and Infection AU - Murray, El AU - KHAGAYI, S AU - OPE, M AU - BIGOGO, G AU - Ochola, R AU - MUTHOKA, P AU - Njenga, K AU - Odhiambo, F AU - Burton, D AU - Laserson, K F AU - Breiman, R F AU - FEIKIN AU - Katz, Ma AD - Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA, katzm@ht.cdc.gov Y1 - 2013/01// PY - 2013 DA - January 2013 SP - 212 EP - 222 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 141 IS - 1 SN - 0950-2688, 0950-2688 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Temperature effects KW - Sensitivity KW - Mortality KW - Age KW - Data processing KW - Respiration KW - Temperature KW - Cough KW - Pharyngitis KW - Infection KW - Influenza KW - Fever KW - Kenya KW - Age groups KW - Hospitals KW - H 1000:Occupational Safety and Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1705062317?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=What+are+the+most+sensitive+and+specific+sign+and+symptom+combinations+for+influenza+in+patients+hospitalized+with+acute+respiratory+illness%3F+Results+from+western+Kenya%2C+January+2007-July+2010&rft.au=Murray%2C+El%3BKHAGAYI%2C+S%3BOPE%2C+M%3BBIGOGO%2C+G%3BOchola%2C+R%3BMUTHOKA%2C+P%3BNjenga%2C+K%3BOdhiambo%2C+F%3BBurton%2C+D%3BLaserson%2C+K+F%3BBreiman%2C+R+F%3BFEIKIN%3BKatz%2C+Ma&rft.aulast=Murray&rft.aufirst=El&rft.date=2013-01-01&rft.volume=141&rft.issue=1&rft.spage=212&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS095026881200043X LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-08-01 N1 - Number of references - 15 N1 - Last updated - 2016-03-30 N1 - SubjectsTermNotLitGenreText - Temperature effects; Fever; Influenza; Age; Data processing; Respiration; Cough; Pharyngitis; Infection; Mortality; Sensitivity; Temperature; Age groups; Hospitals; Kenya DO - http://dx.doi.org/10.1017/S095026881200043X ER - TY - JOUR T1 - Social Media Engagement and Public Health Communication: Implications for Public Health Organizations Being Truly "Social" AN - 1562665340; 20614738 AB - Social media are designed to be engaging, but often are used as a mechanism by public health organizations and practitioners for mass information dissemination rather than engaging audiences in true multi-way conversations and interactions. In this article we define and discuss social media engagement for public health communication. We examine different levels of engagement for public health communication and consider the potential risks, benefits, and challenges of truly embracing the social component in public health practice. Some implications of engagement for public health communication via social media are addressed, and recommendations for future work and research are proposed. JF - Public Health Reviews AU - Heldman, Amy Burnett AU - Schindelar, Jessica AU - Weaver, James B, III AD - Centers for Disease Control and Prevention, Communication, Division of Public Affairs, Atlanta, GA, USA; Centers for Disease Control and Prevention, 1600 E. Clifton Road, MS-E21, Atlanta, GA 30033, USA, evd4@cdc.gov Y1 - 2013 PY - 2013 DA - 2013 SP - 1 EP - 18 PB - Technosdar Ltd., POB 31684 Tel Aviv 61316 Israel VL - 35 IS - 1 SN - 0301-0422, 0301-0422 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Social media KW - engagement KW - public health communication KW - public health KW - Communications KW - Reviews KW - Public health KW - R2 23060:Medical and environmental health KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1562665340?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Public+Health+Reviews&rft.atitle=Social+Media+Engagement+and+Public+Health+Communication%3A+Implications+for+Public+Health+Organizations+Being+Truly+%22Social%22&rft.au=Heldman%2C+Amy+Burnett%3BSchindelar%2C+Jessica%3BWeaver%2C+James+B%2C+III&rft.aulast=Heldman&rft.aufirst=Amy&rft.date=2013-01-01&rft.volume=35&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Public+Health+Reviews&rft.issn=03010422&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Last updated - 2015-04-02 N1 - SubjectsTermNotLitGenreText - Communications; Reviews; Public health ER - TY - JOUR T1 - Association Between Shiftwork and Glomerular Filtration Rate in Police Officers AN - 1492616679; 18903158 AB - Objective: To investigate associations between shiftwork and glomerular filtration rate among white/Hispanic (n = 273) and African American (n = 81) police officers. Methods: Analysis of variance/analysis of variance was utilized to compare mean values of estimated glomerular filtration rate (eGFR) across shiftwork categories. Results: Shiftwork was significantly associated with eGFR among white/Hispanic officers only: day (88.6 plus or minus 2.8), afternoon (90.6 plus or minus 2.9), and night shift (83.1 plus or minus 3.1 mL/min/1.73 m super(2)); afternoon versus night, P = 0.007. Percentage of hours worked on the night shift was inversely associated with mean levels of eGFR, trend P = 0.001. Body mass index modified the association between shiftwork and eGFR (interaction P = 0.038). Among officers with body mass index 25 kg/m super(2) or higher, those who worked the night shift had the lowest mean eGFR (afternoon vs night, P = 0.012; day vs night, P = 0.029). Conclusions: Night-shift work was associated with decreased kidney function among white/Hispanic officers. Longitudinal studies are warranted among all races. JF - Journal of Occupational and Environmental Medicine AU - Charles, LE AU - Gu, J K AU - Fekedulesn, D AU - Andrew, ME AU - Violanti, J M AU - Burchfiel, C M AD - National Institute tor Occupational Safety and Health, HELD/BEB, MS L-4050, 1095 Willowdale Rd, Morgantown, WV 26505, USA, lcharles@cdc.gov PY - 2013 SP - 1323 EP - 1328 VL - 55 IS - 11 SN - 1076-2752, 1076-2752 KW - Health & Safety Science Abstracts KW - Longitudinal studies KW - Shift work KW - Filtration KW - Body mass KW - Kidney KW - Police KW - Ethnic groups KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1492616679?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Association+Between+Shiftwork+and+Glomerular+Filtration+Rate+in+Police+Officers&rft.au=Charles%2C+LE%3BGu%2C+J+K%3BFekedulesn%2C+D%3BAndrew%2C+ME%3BViolanti%2C+J+M%3BBurchfiel%2C+C+M&rft.aulast=Charles&rft.aufirst=LE&rft.date=2013-01-01&rft.volume=55&rft.issue=11&rft.spage=1323&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e3182a299c9 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-12-01 N1 - Last updated - 2015-12-23 N1 - SubjectsTermNotLitGenreText - Longitudinal studies; Shift work; Filtration; Body mass; Kidney; Police; Ethnic groups DO - http://dx.doi.org/10.1097/JOM.0b013e3182a299c9 ER - TY - JOUR T1 - Oxidative Stress, Inflammatory Biomarkers, and Toxicity in Mouse Lung and Liver after Inhalation Exposure to 100% Biodiesel or Petroleum Diesel Emissions AN - 1458530092; 18767962 AB - Over the past decade, soy biodiesel (BD) has become a first alternative energy source that is economically viable and meets requirements of the Clean Air Act. Due to lower mass emissions and reduced hazardous compounds compared to diesel combustion emissions (CE), BD exposure is proposed to produce fewer adverse health effects. However, considering the broad use of BD and its blends in different industries, this assertion needs to be supported and validated by mechanistic and toxicological data. Here, adverse effects were compared in lungs and liver of BALB/cJ mice after inhalation exposure (0, 50, 150, or 500 mu g/m super(3); 4 h/d, 5 d/wk, for 4 wk) to CE from 100% biodiesel (B100) and diesel (D100). Compared to D100, B100 CE produced a significant accumulation of oxidatively modified proteins (carbonyls), an increase in 4-hydroxynonenal (4-HNE), a reduction of protein thiols, a depletion of antioxidant gluthatione (GSH), a dose-related rise in the levels of biomarkers of tissue damage (lactate dehydrogenase, LDH) in lungs, and inflammation (myeloperoxidase, MPO) in both lungs and liver. Significant differences in the levels of inflammatory cytokines interleukin (IL)-6, IL-10, IL-12p70, monocyte chemoattractant protein (MCP)-1, interferon (IFN) gamma , and tumor necrosis factor (TNF)- alpha were detected in lungs and liver upon B100 and D100 CE exposures. Overall, the tissue damage, oxidative stress, inflammation, and cytokine response were more pronounced in mice exposed to BD CE. Further studies are required to understand what combustion products in BD CE accelerate oxidative and inflammatory responses. JF - Journal of Toxicology and Environmental Health, Part A: Current Issues AU - Shvedova, Anna A AU - Yanamala, Naveena AU - Murray, Ashley R AU - Kisin, Elena R AU - Khaliullin, Timur AU - Hatfield, Meghan K AU - Tkach, Alexey V AU - Krantz, Q T AU - Nash, David AU - King, Charly AU - Ian Gilmour, M AU - Gavett, Stephen H AD - Health Effects Laboratory Division, Pathology and Physiology Research Branch, National Institute of Occupational and Safety Health, Morgantown, West Virginia, USA, ats1@cdc.gov Y1 - 2013 PY - 2013 DA - 2013 SP - 907 EP - 921 PB - Taylor & Francis Group Ltd., 2 Park Square Oxford OX14 4RN United Kingdom VL - 76 IS - 15 SN - 1528-7394, 1528-7394 KW - Pollution Abstracts; Environment Abstracts; Toxicology Abstracts KW - Inhalation KW - gamma -Interferon KW - Antioxidants KW - Tumor necrosis factor KW - Clean Air Act KW - Interleukin 12 KW - Oxidative stress KW - Petroleum KW - Emissions KW - Bioindicators KW - Mice KW - Tumors KW - Toxicity KW - biomarkers KW - L-Lactate dehydrogenase KW - Combustion KW - Inflammation KW - Soybeans KW - Interferon KW - Lung KW - Energy KW - Liver KW - Proteins KW - Diesel KW - Biofuels KW - P 0000:AIR POLLUTION KW - X 24360:Metals KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1458530092?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.atitle=Oxidative+Stress%2C+Inflammatory+Biomarkers%2C+and+Toxicity+in+Mouse+Lung+and+Liver+after+Inhalation+Exposure+to+100%25+Biodiesel+or+Petroleum+Diesel+Emissions&rft.au=Shvedova%2C+Anna+A%3BYanamala%2C+Naveena%3BMurray%2C+Ashley+R%3BKisin%2C+Elena+R%3BKhaliullin%2C+Timur%3BHatfield%2C+Meghan+K%3BTkach%2C+Alexey+V%3BKrantz%2C+Q+T%3BNash%2C+David%3BKing%2C+Charly%3BIan+Gilmour%2C+M%3BGavett%2C+Stephen+H&rft.aulast=Shvedova&rft.aufirst=Anna&rft.date=2013-01-01&rft.volume=76&rft.issue=15&rft.spage=907&rft.isbn=&rft.btitle=&rft.title=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.issn=15287394&rft_id=info:doi/10.1080%2F15287394.2013.825217 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-11-01 N1 - Last updated - 2015-03-20 N1 - SubjectsTermNotLitGenreText - Inhalation; gamma -Interferon; Antioxidants; Tumor necrosis factor; Toxicity; biomarkers; Soybeans; Inflammation; Combustion; L-Lactate dehydrogenase; Interleukin 12; Interferon; Lung; Oxidative stress; Petroleum; Energy; Liver; Diesel; Biofuels; Bioindicators; Mice; Tumors; Clean Air Act; Emissions; Proteins DO - http://dx.doi.org/10.1080/15287394.2013.825217 ER - TY - JOUR T1 - Investigation of the Pulmonary Bioactivity of Double-Walled Carbon Nanotubes AN - 1458528688; 18767963 AB - Double-walled carbon nanotubes (DWCNT) are a rather new and unexplored variety of carbon nanotubes. Previously conducted studies established that exposure to a variety of carbon nanotubes produced lung inflammation and fibrosis in mice after pharyngeal aspiration. However, the bioactivity of double-walled carbon nanotubes (DWCNT) has not been determined. In this study, the hypothesis that DWCNT would induce pulmonary toxicity was explored by analyzing the pulmonary bioactivity of DWCNT. To test this hypothesis, C57Bl/6 mice were exposed to DWCNT by pharyngeal aspiration. Mice underwent whole-lung lavage (WLL) to assess pulmonary inflammation and injury, and lung tissue was examined histologically for development of pulmonary disease as a function of dose and time. The results showed that DWCNT exposure produced a dose-dependent increase in WLL polymorphonuclear leukocytes (PMN), indicating that DWCNT exposure initiated pulmonary inflammation. DWCNT exposure also produced a dose-dependent rise in lactate dehydrogenase (LDH) activity, as well as albumin levels, in WLL fluid, indicating that DWCNT exposure promoted cytotoxicity as well as decreases in the integrity of the blood-gas barrier in the lung, respectively. In addition, at 7 and 56 d postexposure, the presence of significant alveolitis and fibrosis was noted in mice exposed to 40 mu g/mouse DWCNT. In conclusion, this study provides insight into previously uninvestigated pulmonary bioactivity of DWCNT exposure. Data indicate that DWCNT exposure promotes inflammation, injury, and fibrosis in the lung. JF - Journal of Toxicology and Environmental Health, Part A: Current Issues AU - Sager, Tina M AU - Wolfarth, Michael W AU - Battelli, Lori A AU - Leonard, Stephen S AU - Andrew, Michael AU - Steinbach, Thomas AU - Endo, Morinobu AU - Tsuruoka, Shuji AU - Porter, Dale W AU - Castranova, Vincent AD - National Institute for Occupational Safety and Health, Health Effects Laboratory Division, Pathology and Physiology Research Branch, Morgantown, West Virginia, USA, sst2@cdc.gov Y1 - 2013 PY - 2013 DA - 2013 SP - 922 EP - 936 PB - Taylor & Francis Group Ltd., 2 Park Square Oxford OX14 4RN United Kingdom VL - 76 IS - 15 SN - 1528-7394, 1528-7394 KW - Pollution Abstracts; Environment Abstracts; Toxicology Abstracts KW - Data processing KW - Pharynx KW - Injuries KW - Fibrosis KW - Leukocytes (polymorphonuclear) KW - Lung diseases KW - Mice KW - Toxicity KW - Nanotechnology KW - Inflammation KW - L-Lactate dehydrogenase KW - Cytotoxicity KW - Carbon KW - Lung KW - Albumin KW - nanotubes KW - Alveolitis KW - X 24360:Metals KW - P 6000:TOXICOLOGY AND HEALTH KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1458528688?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.atitle=Investigation+of+the+Pulmonary+Bioactivity+of+Double-Walled+Carbon+Nanotubes&rft.au=Sager%2C+Tina+M%3BWolfarth%2C+Michael+W%3BBattelli%2C+Lori+A%3BLeonard%2C+Stephen+S%3BAndrew%2C+Michael%3BSteinbach%2C+Thomas%3BEndo%2C+Morinobu%3BTsuruoka%2C+Shuji%3BPorter%2C+Dale+W%3BCastranova%2C+Vincent&rft.aulast=Sager&rft.aufirst=Tina&rft.date=2013-01-01&rft.volume=76&rft.issue=15&rft.spage=922&rft.isbn=&rft.btitle=&rft.title=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.issn=15287394&rft_id=info:doi/10.1080%2F15287394.2013.825571 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-11-01 N1 - Last updated - 2015-03-20 N1 - SubjectsTermNotLitGenreText - Pharynx; Data processing; Injuries; Fibrosis; Leukocytes (polymorphonuclear); Lung diseases; Toxicity; L-Lactate dehydrogenase; Inflammation; Cytotoxicity; Carbon; Albumin; nanotubes; Alveolitis; Lung; Mice; Nanotechnology DO - http://dx.doi.org/10.1080/15287394.2013.825571 ER - TY - JOUR T1 - The Relationship between a Family-Focused Preventive Intervention, Parenting Practices, and Exposure to Violence during the Transition to Adolescence: Testing a Mediational Model AN - 1417521083; 201306727 AB - To prevent youth violence, the GREAT Families program was implemented with a selective sample of 1,196 families of sixth-grade children from low-income schools in 4 cities making the transition to adolescence. To assess intervention effects, we used pre- and posttest data to estimate a structural model to test the hypothesis that random assignment to the intervention would predict changes in parenting practices, which in turn would predict changes in exposure to violence (i.e., a mediational model). We found that participation in GREAT was significantly related to changes in parenting practices and these changes significantly predicted changes in violence exposure. Furthermore, adolescents who reported greater increases in exposure to violence also tended to experience greater decreases in parental monitoring, discipline, and involvement. Implications for future research and prevention efforts are discussed. Adapted from the source document. JF - Journal of Aggression, Maltreatment & Trauma AU - Matjasko, Jennifer L AU - Vivolo-Kantor, Alana M AU - Henry, David B AU - Gorman-Smith, Deborah AU - Schoeny, Michael E AD - National Center for Injury Prevention and Control, Division of Violence Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA Y1 - 2013/01// PY - 2013 DA - January 2013 SP - 45 EP - 66 PB - Taylor & Francis, Philadelphia PA VL - 22 IS - 1 SN - 1092-6771, 1092-6771 KW - Cities KW - Low Income Groups KW - Prevention KW - Participation KW - Family Violence KW - Intervention KW - Childrearing Practices KW - Violence KW - Adolescents KW - article KW - 6143: child & family welfare UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1417521083?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocialservices&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Aggression%2C+Maltreatment+%26+Trauma&rft.atitle=The+Relationship+between+a+Family-Focused+Preventive+Intervention%2C+Parenting+Practices%2C+and+Exposure+to+Violence+during+the+Transition+to+Adolescence%3A+Testing+a+Mediational+Model&rft.au=Matjasko%2C+Jennifer+L%3BVivolo-Kantor%2C+Alana+M%3BHenry%2C+David+B%3BGorman-Smith%2C+Deborah%3BSchoeny%2C+Michael+E&rft.aulast=Matjasko&rft.aufirst=Jennifer&rft.date=2013-01-01&rft.volume=22&rft.issue=1&rft.spage=45&rft.isbn=&rft.btitle=&rft.title=Journal+of+Aggression%2C+Maltreatment+%26+Trauma&rft.issn=10926771&rft_id=info:doi/10.1080%2F10926771.2013.743947 LA - English DB - Social Services Abstracts N1 - Date revised - 2013-08-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Violence; Childrearing Practices; Intervention; Adolescents; Family Violence; Low Income Groups; Prevention; Cities; Participation DO - http://dx.doi.org/10.1080/10926771.2013.743947 ER - TY - JOUR T1 - Behavioral and Attitudinal Factors Differentiating Male Intimate Partner Violence Perpetrators With and Without a History of Childhood Family Violence AN - 1373430045; 201305897 AB - This study utilized a sample of men (N=340) charged with assault against a female partner to assess differences among IPV perpetrators with and without a history of childhood family violence on factors such as angry, controlling and violent behaviors, substance use related behaviors, and attitudes towards women. Over two-thirds of the sample reported childhood exposure to maltreatment or witnessing IPV. Chi-square analyses and t-tests indicated significant differences between perpetrators with and without a history of family violence on eight of eleven measures. Findings suggest perpetrators with a family violence history more strongly endorse ideas that present women and feminine attributes in a negative light. This research demonstrates that while exposure to family violence during childhood is not necessary for IPV to occur, its presence may be a marker for more severe attitudinal and behavioral problems. Findings highlight the need for primary prevention efforts and can inform secondary prevention strategies. Adapted from the source document. JF - Journal of Family Violence AU - Lee, Rosalyn D AU - Walters, Mikel L AU - Hall, Jeffrey E AU - Basile, Kathleen C AD - Division of Violence Prevention, National Center for Injury Prevention and Control, U.S. Centers for Disease Control and Prevention Y1 - 2013/01// PY - 2013 DA - January 2013 SP - 85 EP - 94 PB - Springer Science+Business Media, Inc, New York, NY VL - 28 IS - 1 SN - 0885-7482, 0885-7482 KW - Attitudes KW - Prevention KW - Childhood KW - Males KW - Sex Differences KW - Family Violence KW - Assault KW - Females KW - Aggression KW - article KW - 6143: child & family welfare UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1373430045?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocialservices&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Family+Violence&rft.atitle=Behavioral+and+Attitudinal+Factors+Differentiating+Male+Intimate+Partner+Violence+Perpetrators+With+and+Without+a+History+of+Childhood+Family+Violence&rft.au=Lee%2C+Rosalyn+D%3BWalters%2C+Mikel+L%3BHall%2C+Jeffrey+E%3BBasile%2C+Kathleen+C&rft.aulast=Lee&rft.aufirst=Rosalyn&rft.date=2013-01-01&rft.volume=28&rft.issue=1&rft.spage=85&rft.isbn=&rft.btitle=&rft.title=Journal+of+Family+Violence&rft.issn=08857482&rft_id=info:doi/10.1007%2Fs10896-012-9475-8 LA - English DB - Social Services Abstracts N1 - Date revised - 2013-07-01 N1 - Last updated - 2016-09-28 N1 - CODEN - JFVIEV N1 - SubjectsTermNotLitGenreText - Family Violence; Childhood; Prevention; Females; Sex Differences; Aggression; Assault; Attitudes; Males DO - http://dx.doi.org/10.1007/s10896-012-9475-8 ER - TY - JOUR T1 - Assessment of hydroxylated metabolites of polychlorinated biphenyls as potential xenoestrogens: a QSAR comparative analysis∗. AN - 1366823179; 23557136 AB - Alternative methods, including quantitative structure-activity relationships (QSAR), are being used increasingly when appropriate data for toxicity evaluation of chemicals are not available. Approximately 40 mono-hydroxylated polychlorinated biphenyls (OH-PCBs) have been identified in humans. They represent a health and environmental concern because some of them have been shown to have agonist or antagonist interactions with human hormone receptors. This could lead to modulation of steroid hormone receptor pathways and endocrine system disruption. We performed QSAR analyses using available estrogenic activity (human estrogen receptor ER alpha) data for 71 OH-PCBs. The modelling was performed using multiple molecular descriptors including electronic, molecular, constitutional, topological, and geometrical endpoints. Multiple linear regressions and recursive partitioning were used to best fit descriptors. The results show that the position of the hydroxyl substitution, polarizability, and meta adjacent un-substituted carbon pairs at the phenolic ring contribute towards greater estrogenic activity for these chemicals. These comparative QSAR models may be used for predictive toxicity, and identification of health consequences of PCB metabolites that lack empirical data. Such information will help prioritize such molecules for additional testing, guide future basic laboratory research studies, and help the health/risk assessment community understand the complex nature of chemical mixtures. JF - SAR and QSAR in environmental research AU - Ruiz, P AU - Myshkin, E AU - Quigley, P AU - Faroon, O AU - Wheeler, J S AU - Mumtaz, M M AU - Brennan, R J AD - Division of Toxicology and Human Health Sciences, Agency for Toxic Substances and Disease Registry, Atlanta, USA. pruiz@cdc.gov Y1 - 2013 PY - 2013 DA - 2013 SP - 393 EP - 416 VL - 24 IS - 5 KW - Estrogen Receptor alpha KW - 0 KW - estrogen receptor alpha, human KW - Polychlorinated Biphenyls KW - DFC2HB4I0K KW - Index Medicus KW - Quantitative Structure-Activity Relationship KW - Humans KW - Models, Statistical KW - Polychlorinated Biphenyls -- toxicity KW - Polychlorinated Biphenyls -- metabolism KW - Estrogen Receptor alpha -- agonists UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1366823179?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=SAR+and+QSAR+in+environmental+research&rft.atitle=Assessment+of+hydroxylated+metabolites+of+polychlorinated+biphenyls+as+potential+xenoestrogens%3A+a+QSAR+comparative+analysis%E2%88%97.&rft.au=Ruiz%2C+P%3BMyshkin%2C+E%3BQuigley%2C+P%3BFaroon%2C+O%3BWheeler%2C+J+S%3BMumtaz%2C+M+M%3BBrennan%2C+R+J&rft.aulast=Ruiz&rft.aufirst=P&rft.date=2013-01-01&rft.volume=24&rft.issue=5&rft.spage=393&rft.isbn=&rft.btitle=&rft.title=SAR+and+QSAR+in+environmental+research&rft.issn=1029-046X&rft_id=info:doi/10.1080%2F1062936X.2013.781537 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2014-01-22 N1 - Date created - 2013-06-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1080/1062936X.2013.781537 ER - TY - JOUR T1 - Health outcomes of HIV-exposed uninfected African infants AN - 1328522250; 17879559 AB - Objectives: To evaluate severe (grade 3/4) morbidity and mortality in HIV-exposed, uninfected infants. Design: Secondary data analysis of The Breastfeeding, Antiretrovirals, and Nutrition (BAN) clinical trial. Methods: BAN randomized 2369 mother-infant pairs to maternal, infant, or no extended antiretroviral prophylaxis during breastfeeding. Morbidity outcomes examined were pneumonia/serious febrile illness, diarrhea/growth faltering, and malaria. Infant death was defined as neonatal ( less than or equal to 30 days of life), and postneonatal (31 days to 48 weeks of life). Cox proportional hazards models were used to evaluate the effect of covariates on infant morbidity and mortality. Results: The rate of pneumonia/serious febrile illness was highest in the first 12 weeks (0.83/100 person-weeks) before rapidly decreasing; rates of all morbidity outcomes increased after 24 weeks. Rates of pneumonia/serious febrile illness and diarrhea/growth faltering were higher during the rainy season. Prophylactic infant cotrimoxazole significantly decreased the rates of all morbidity outcomes. White blood cell (WBC) count less than 9000/ mu l at birth was associated with increased diarrhea/growth faltering [adjusted hazard ratio (aHR) 1.73, P = 0.04] and malaria (aHR 2.18, P = 0.02). Low birth weight (2000-2499g) was associated with neonatal death (aHR 12.3, P<0.001). Factors associated with postneonatal death included rainy season (aHR 4.24, P= 0.002), infant cotrimoxazole (aHR 0.48, P = 0.03), and low infant WBC count at birth (aHR 2.53, P=0.02). Conclusion: Infant morbidity rates increased after 24 weeks, when BAN infants weaned. Introduction of prophylactic cotrimoxazole was associated with reduced rates of morbidity and mortality in HIV-exposed uninfected infants. Unexpectedly, a low WBC count at birth was significantly associated with later infant morbidity and mortality in this cohort. JF - AIDS AU - Kourtis AU - Wiener, J AU - Kayira, D AU - Chasela, C AU - Ellington AU - Hyde, L AU - Hosseinipour, M AU - van der Horst, C AU - Jamieson, D J AD - Centers for Disease Control and Prevention, 4770 Buford Highway MS K34, Atlanta, GA 30341, USA, AKourtis@cdc.gov Y1 - 2013///0, PY - 2013 DA - 0, 2013 SP - 749 EP - 759 VL - 27 IS - 5 SN - 0269-9370, 0269-9370 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Health & Safety Science Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - Birth weight KW - Acquired immune deficiency syndrome KW - Human diseases KW - Parturition KW - cotrimoxazole KW - Malaria KW - Clinical trials KW - Nutrition KW - Morbidity KW - Hazards KW - Growth KW - Rainy season KW - Antiviral agents KW - Breast feeding KW - Blood cells KW - Mortality KW - Data processing KW - Diarrhea KW - Leukocytes KW - Antiretroviral agents KW - Low-birth-weight KW - Human immunodeficiency virus KW - Prophylaxis KW - Africa KW - Neonates KW - Pneumonia KW - Mortality causes KW - Infants KW - V 22360:AIDS and HIV KW - Q1 08484:Species interactions: parasites and diseases KW - F 06910:Microorganisms & Parasites KW - Q5 08524:Public health, medicines, dangerous organisms KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1328522250?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS&rft.atitle=Health+outcomes+of+HIV-exposed+uninfected+African+infants&rft.au=Kourtis%3BWiener%2C+J%3BKayira%2C+D%3BChasela%2C+C%3BEllington%3BHyde%2C+L%3BHosseinipour%2C+M%3Bvan+der+Horst%2C+C%3BJamieson%2C+D+J&rft.aulast=Kourtis&rft.aufirst=&rft.date=2013-01-01&rft.volume=27&rft.issue=5&rft.spage=749&rft.isbn=&rft.btitle=&rft.title=AIDS&rft.issn=02699370&rft_id=info:doi/10.1097%2FQAD.0b013e32835ca29f LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-04-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Hazards; Human diseases; Growth; Rainy season; Prophylaxis; Parturition; Malaria; Blood cells; Mortality causes; Mortality; Birth weight; Diarrhea; Data processing; Leukocytes; cotrimoxazole; Nutrition; Clinical trials; Morbidity; Antiviral agents; Breast feeding; Neonates; Pneumonia; Infants; Acquired immune deficiency syndrome; Antiretroviral agents; Low-birth-weight; Human immunodeficiency virus; Africa DO - http://dx.doi.org/10.1097/QAD.0b013e32835ca29f ER - TY - JOUR T1 - Role of Nrf2 in Oxidative Stress and Toxicity AN - 1318696204; 17786994 AB - Organismal life encounters reactive oxidants from internal metabolism and environmental toxicant exposure. Reactive oxygen and nitrogen species cause oxidative stress and are traditionally viewed as being harmful. On the other hand, controlled production of oxidants in normal cells serves useful purposes to regulate signaling pathways. Reactive oxidants are counterbalanced by complex antioxidant defense systems regulated by a web of pathways to ensure that the response to oxidants is adequate for the body's needs. A recurrent theme in oxidant signaling and antioxidant defense is reactive cysteine thiol-based redox signaling. The nuclear factor erythroid 2-related factor 2 (Nrf2) is an emerging regulator of cellular resistance to oxidants. Nrf2 controls the basal and induced expression of an array of antioxidant response element-dependent genes to regulate the physiological and pathophysiological outcomes of oxidant exposure. This review discusses the impact of Nrf2 on oxidative stress and toxicity and how Nrf2 senses oxidants and regulates antioxidant defense. JF - Annual Review of Pharmacology and Toxicology AU - Ma, Q AD - Receptor Biology Laboratory, Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, qam1@cdc.gov Y1 - 2013 PY - 2013 DA - 2013 SP - 401 EP - 426 VL - 53 SN - 0362-1642, 0362-1642 KW - Toxicology Abstracts KW - Oxygen KW - Antioxidants KW - Toxicants KW - Oxidative stress KW - Cysteine KW - Reviews KW - Toxicity KW - Oxidants KW - Metabolism KW - Signal transduction KW - Nitrogen KW - X 24310:Pharmaceuticals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1318696204?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annual+Review+of+Pharmacology+and+Toxicology&rft.atitle=Role+of+Nrf2+in+Oxidative+Stress+and+Toxicity&rft.au=Ma%2C+Q&rft.aulast=Ma&rft.aufirst=Q&rft.date=2013-01-01&rft.volume=53&rft.issue=&rft.spage=401&rft.isbn=&rft.btitle=&rft.title=Annual+Review+of+Pharmacology+and+Toxicology&rft.issn=03621642&rft_id=info:doi/10.1146%2Fannurev-pharmtox-011112-140320 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-03-01 N1 - Last updated - 2013-11-04 N1 - SubjectsTermNotLitGenreText - Oxygen; Antioxidants; Toxicants; Cysteine; Oxidative stress; Reviews; Toxicity; Metabolism; Oxidants; Nitrogen; Signal transduction DO - http://dx.doi.org/10.1146/annurev-pharmtox-011112-140320 ER - TY - JOUR T1 - Time series analysis of fine particulate matter and asthma reliever dispensations in populations affected by forest fires AN - 1315622454; 17733626 AB - Background: Several studies have evaluated the association between forest fire smoke and acute exacerbations of respiratory diseases, but few have examined effects on pharmaceutical dispensations. We examine the associations between daily fine particulate matter (PM sub(2.5)) and pharmaceutical dispensations for salbutamol in forest fire-affected and non-fire-affected populations in British Columbia (BC), Canada. Methods: We estimated PM sub(2.5) exposure for populations in administrative health areas using measurements from central monitors. Remote sensing data on fires were used to classify the populations as fire-affected or non-fire-affected, and to identify extreme fire days. Daily counts of salbutamol dispensations between 2003 and 2010 were extracted from the BC PharmaNet database. We estimated rate ratios (RR) and 95% confidence intervals (CIs) for each population during all fire seasons and on extreme fire days, adjusted for temperature, humidity, and temporal trends. Overall effects for fire-affected and non-fire-affected populations were estimated via meta-regression. Results: Fire season PM sub(2.5) was positively associated with salbutamol dispensations in all fire-affected populations, with a meta-regression RR (95% CI) of 1.06 (1.04-1.07) for a 10 ug/m super(3) increase. Fire season PM sub(2.5) was not significantly associated with salbutamol dispensations in non-fire-affected populations, with a meta-regression RR of 1.00 (0.98-1.01). On extreme fire days PM sub(2.5) was positively associated with salbutamol dispensations in both population types, with a global meta-regression RR of 1.07 (1.04 - 1.09). Conclusions: Salbutamol dispensations were clearly associated with fire-related PM sub(2.5). Significant associations were observed in smaller populations (range: 8,000 to 170,000 persons, median: 26,000) than those reported previously, suggesting that salbutamol dispensations may be a valuable outcome for public health surveillance during fire events. JF - Environmental Health (London) AU - Elliott, Catherine T AU - Henderson, Sarah B AU - Wan, Victoria AD - British Columbia Center for Disease Control, Environmental Health Services, BC Centre for Disease Control, Main Floor, 655 12th Ave W, Vancouver, BC, V5Z 4R4, Canada Y1 - 2013 PY - 2013 DA - 2013 SP - 11 PB - BioMed Central Ltd., Middlesex House London W1T 4LB United Kingdom VL - 12 IS - 1 SN - 1476-069X, 1476-069X KW - Health & Safety Science Abstracts KW - Canada, British Columbia KW - Fires KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1315622454?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Health+%28London%29&rft.atitle=Time+series+analysis+of+fine+particulate+matter+and+asthma+reliever+dispensations+in+populations+affected+by+forest+fires&rft.au=Elliott%2C+Catherine+T%3BHenderson%2C+Sarah+B%3BWan%2C+Victoria&rft.aulast=Elliott&rft.aufirst=Catherine&rft.date=2013-01-01&rft.volume=12&rft.issue=1&rft.spage=11&rft.isbn=&rft.btitle=&rft.title=Environmental+Health+%28London%29&rft.issn=1476069X&rft_id=info:doi/10.1186%2F1476-069X-12-11 L2 - http://www.ehjournal.net/content/12/1/11 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-03-01 N1 - Number of references - 1 N1 - Last updated - 2014-03-10 N1 - SubjectsTermNotLitGenreText - Fires; Canada, British Columbia DO - http://dx.doi.org/10.1186/1476-069X-12-11 ER - TY - JOUR T1 - High HIV incidence and prevalence and associated factors among young MSM, 2008 AN - 1291602066; 17641114 AB - Objective: To estimate HIV prevalence, annual HIV incidence density, and factors associated with HIV infection among young MSM in the United States. Design: The 2008 National HIV Behavioral Surveillance System (NHBS), a cross-sectional survey conducted in 21 US cities. Methods: NHBS respondents included in the analysis were MSM aged 18-24 with a valid HIV test who reported at least one male sex partner in the past year. We calculated HIV prevalence and estimated annual incidence density (number of HIV infections/total number of person-years at risk). Generalized estimating equations were used to determine factors associated with testing positive for HIV. Results: Of 1889 young MSM, 198 (10%) had a positive HIV test; of these, 136 (69%) did not report previously testing HIV positive when interviewed. Estimated annual HIV incidence density was 2.9%; incidence was highest for blacks. Among young MSM who did not report being HIV infected, factors associated with testing HIV positive included black race; less than high school education; using both alcohol and drugs before or during last sex; having an HIV test more than 12 months ago; and reporting a visit to a medical provider in the past year. Conclusion: HIV prevalence and estimated incidence density for young MSM were high. Individual risk behaviors did not fully explain HIV risk, emphasizing the need to address sociodemographic and structural-level factors in public health interventions targeted toward young MSM. JF - AIDS AU - Balaji, AB AU - Bowles, KE AU - Le, B C AU - Paz-Bailey, G AU - Oster, A M AD - Centers for Disease Control and Prevention, 1600 Clifton Road, N.E., MS E-46, Atlanta, CA 30333, USA, dvi7@cdc.gov Y1 - 2013 PY - 2013 DA - 2013 SP - 269 EP - 278 VL - 27 IS - 2 SN - 0269-9370, 0269-9370 KW - Risk Abstracts; Health & Safety Science Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - Alcohol KW - Acquired immune deficiency syndrome KW - Mathematical models KW - Intervention KW - Infection KW - Public health KW - Cities KW - USA KW - Education KW - Human immunodeficiency virus KW - Risk factors KW - alcohols KW - Drugs KW - Races KW - Sex KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health KW - F 06910:Microorganisms & Parasites KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1291602066?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS&rft.atitle=High+HIV+incidence+and+prevalence+and+associated+factors+among+young+MSM%2C+2008&rft.au=Balaji%2C+AB%3BBowles%2C+KE%3BLe%2C+B+C%3BPaz-Bailey%2C+G%3BOster%2C+A+M&rft.aulast=Balaji&rft.aufirst=AB&rft.date=2013-01-01&rft.volume=27&rft.issue=2&rft.spage=269&rft.isbn=&rft.btitle=&rft.title=AIDS&rft.issn=02699370&rft_id=info:doi/10.1097%2FQAD.0b013e32835ad489 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Mathematical models; Risk factors; alcohols; Infection; Drugs; Races; Public health; Sex; Cities; Alcohol; Education; Acquired immune deficiency syndrome; Human immunodeficiency virus; Intervention; USA DO - http://dx.doi.org/10.1097/QAD.0b013e32835ad489 ER - TY - JOUR T1 - The role of toxicologists and poison centers during and after a nuclear power plant emergency. AN - 1273497014; 23311539 JF - Clinical toxicology (Philadelphia, Pa.) AU - Kazzi, Z N AU - Miller, C W AD - Centers for Disease Control and Prevention, Radiation Studies Branch, Division of Environmental Hazards and Health Effects, National Center for Environmental Health, Atlanta, GA 30341, USA. zkazzi@cdc.gov Y1 - 2013/01// PY - 2013 DA - January 2013 SP - 1 EP - 2 VL - 51 IS - 1 KW - Abridged Index Medicus KW - Index Medicus KW - United States KW - Professional Role KW - Centers for Disease Control and Prevention (U.S.) KW - Humans KW - Toxicology -- manpower KW - Fukushima Nuclear Accident KW - Emergencies KW - Japan KW - Poison Control Centers -- manpower KW - Radioactive Hazard Release KW - Nuclear Power Plants KW - Ecotoxicology -- manpower UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1273497014?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+toxicology+%28Philadelphia%2C+Pa.%29&rft.atitle=The+role+of+toxicologists+and+poison+centers+during+and+after+a+nuclear+power+plant+emergency.&rft.au=Kazzi%2C+Z+N%3BMiller%2C+C+W&rft.aulast=Kazzi&rft.aufirst=Z&rft.date=2013-01-01&rft.volume=51&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Clinical+toxicology+%28Philadelphia%2C+Pa.%29&rft.issn=1556-9519&rft_id=info:doi/10.3109%2F15563650.2012.757319 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2013-03-07 N1 - Date created - 2013-01-14 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.3109/15563650.2012.757319 ER - TY - JOUR T1 - Blood lead level analysis among refugee children resettled in New Hampshire and Rhode Island. AN - 1273320928; 23294389 AB - To examine the association between refugee status and elevated blood lead levels (EBLLs) among children living in two U.S. cities and to assess the effect of the Centers for Disease Control and Prevention recommendations for BLL testing of newly emigrated refugee children for EBLLs. A longitudinal study was conducted of 1,007 refugee children and 953 nonrefugee children living, when blood testing occurred, in the same buildings in Manchester, New Hampshire and Providence, Rhode Island. Surveillance and blood lead data were collected from both sites, including demographic information, BLLs, sample type, refugee status, and age of housing. Refugee children living in Manchester were statistically significantly more likely to have an EBLL compared with nonrefugee children even after controlling for potential confounders. We did not find this association in Providence. Compared with before enactment, the mean time of refugee children to fall below 10 μg/dL was significantly shorter after the recommendations to test newly emigrated children were enacted. Refugee children living in Manchester were significantly more likely to have an EBLL compared with nonrefugee children. And among refugee children, we found a statistically significant difference in the mean days to BLL decline <10 μg/dL before and after recommendations to test newly emigrated children. © 2012 Wiley Periodicals, Inc. JF - Public health nursing (Boston, Mass.) AU - Raymond, Jaime S AU - Kennedy, Chinaro AU - Brown, Mary Jean AD - Division of Emergency and Environmental Health Services, Centers for Disease Control and Prevention, National Center for Environmental Health, Healthy Homes and Lead Poisoning Prevention Branch, Atlanta, Georgia 30341, USA. jraymond@cdc.gov Y1 - 2013/01// PY - 2013 DA - January 2013 SP - 70 EP - 79 VL - 30 IS - 1 KW - Environmental Pollutants KW - 0 KW - Lead KW - 2P299V784P KW - Index Medicus KW - Nursing KW - Housing KW - Rhode Island KW - Humans KW - Child KW - Longitudinal Studies KW - Environmental Monitoring -- statistics & numerical data KW - Child, Preschool KW - New Hampshire KW - Infant KW - Case-Control Studies KW - Environmental Exposure KW - Emigrants and Immigrants KW - Adolescent KW - Environmental Pollutants -- blood KW - Male KW - Female KW - Lead Poisoning -- prevention & control KW - Lead Poisoning -- ethnology KW - Lead Poisoning -- blood KW - Lead Poisoning -- epidemiology KW - Refugees -- statistics & numerical data KW - Lead -- blood UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1273320928?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Public+health+nursing+%28Boston%2C+Mass.%29&rft.atitle=Blood+lead+level+analysis+among+refugee+children+resettled+in+New+Hampshire+and+Rhode+Island.&rft.au=Raymond%2C+Jaime+S%3BKennedy%2C+Chinaro%3BBrown%2C+Mary+Jean&rft.aulast=Raymond&rft.aufirst=Jaime&rft.date=2013-01-01&rft.volume=30&rft.issue=1&rft.spage=70&rft.isbn=&rft.btitle=&rft.title=Public+health+nursing+%28Boston%2C+Mass.%29&rft.issn=1525-1446&rft_id=info:doi/10.1111%2Fphn.12007 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2013-06-03 N1 - Date created - 2013-01-08 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1111/phn.12007 ER - TY - JOUR T1 - Influenza Viruses in Nigeria, 2009-2010: Results From the First 17 Months of a National Influenza Sentinel Surveillance System AN - 1642621767; 20900091 AB - Background. Influenza surveillance data from tropical, sub-Saharan African countries are limited. To better understand the epidemiology of influenza, Nigeria initiated influenza surveillance in 2008. Methods. Outpatients with influenza-like illness (ILI) and inpatients with severe acute respiratory illness (SARI) were enrolled at 4 sentinel facilities. Epidemiologic data were obtained, and respiratory specimens were tested for influenza viruses, using real-time reverse-transcription polymerase chain reaction assays. Results. During April 2009-August 2010, 2841 patients were enrolled. Of 2803 specimens tested, 217 (7.7%) were positive for influenza viruses (167 [8%] were from subjects with ILI, 17 [5%] were from subjects with SARI, and 33 were from subjects with an unclassified condition). During the prepandemic period, subtype H3N2 (A[H3N2]) was the dominant circulating influenza A virus subtype; 2009 pandemic influenza A virus subtype H1N1 (A[H1N1]pdm09) replaced A(H3N2) as the dominant circulating virus during November 2009. Among persons with ILI, A(H1N1)pdm09 was most frequently found in children aged 5-17 years, whereas among subjects with SARI, it was most frequently found in persons aged > or =65 years. The percentage of specimens that tested positive for influenza viruses peaked at 18.9% in February 2010, and the majority were A(H1N1)pdm09. Conclusions. Influenza viruses cause ILI and SARI in Nigeria. Data from additional years are needed to better understand the epidemiology and seasonality of influenza viruses in Nigeria. JF - Journal of Infectious Diseases AU - Dalhatu, Ibrahim T AU - Medina-Marino, Andrew AU - Olsen, Sonja J AU - Hwang, Inzune AU - Gubio, Aisha Bintu AU - Ekanem, Ekanem E AU - Coker, E B A AU - Akpan, Henry AU - Adedeji, Adebayo Abel AD - US Centers for Disease Control and Prevention-Nigeria Plot 252A Herbert Macaulay Way, Maina Court, Central Business District, Federal Capital Territory, Abuja, Nigeria, dalhatui@ng.cdc.gov Y1 - 2012/12/15/ PY - 2012 DA - 2012 Dec 15 SP - S121 EP - S128 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 206 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Nigeria KW - Data processing KW - Viruses KW - Children KW - Influenza KW - pandemics KW - Infectious diseases KW - Epidemiology KW - Influenza A virus KW - Africa KW - Polymerase chain reaction KW - Seasonal variations KW - H 1000:Occupational Safety and Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1642621767?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Influenza+Viruses+in+Nigeria%2C+2009-2010%3A+Results+From+the+First+17+Months+of+a+National+Influenza+Sentinel+Surveillance+System&rft.au=Dalhatu%2C+Ibrahim+T%3BMedina-Marino%2C+Andrew%3BOlsen%2C+Sonja+J%3BHwang%2C+Inzune%3BGubio%2C+Aisha+Bintu%3BEkanem%2C+Ekanem+E%3BCoker%2C+E+B+A%3BAkpan%2C+Henry%3BAdedeji%2C+Adebayo+Abel&rft.aulast=Dalhatu&rft.aufirst=Ibrahim&rft.date=2012-12-15&rft.volume=206&rft.issue=&rft.spage=S121&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjis584 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - pandemics; Data processing; Epidemiology; Polymerase chain reaction; Children; Seasonal variations; Influenza; Infectious diseases; Viruses; Influenza A virus; Nigeria; Africa DO - http://dx.doi.org/10.1093/infdis/jis584 ER - TY - JOUR T1 - A Comparison of the Interactive Systems Framework (ISF) for Dissemination and Implementation and the CDC Division of HIV/AIDS Prevention's Research-to-Practice Model for Behavioral Interventions AN - 1434016548; 18526375 AB - Translating evidence-based HIV/STD prevention interventions and research findings into applicable HIV prevention practice has become an important challenge for the fields of community psychology and public health due to evidence-based interventions and evidence-based practice being given higher priority and endorsement by federal, state, and local health department funders. The Interactive Systems Framework (ISF) for Dissemination and Implementation and the Division of HIV/AIDS Prevention (DHAP) Research-to-Practice model both address this challenge. The DHAP model and the ISF are each presented with a brief history and an introduction of their features from synthesis of research findings through translation into intervention materials to implementation by prevention providers. This paper describes why the ISF and the DHAP model were developed and the similarities and differences between them. Specific examples of the use of the models to translate research to practice and the subsequent implications for support of each model are provided. The paper concludes that the ISF and the DHAP model are truly complementary with some unique differences, while both contribute substantially to addressing the gap between identifying effective programs and ensuring their widespread adoption in the field. JF - American Journal of Community Psychology AU - Collins, Charles B AU - Edwards, Arlene E AU - Jones, Patricia L AU - Kay, Linda AU - Cox, Pamela J AU - Puddy, Richard W AD - Capacity Building Branch, Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, CORP Bldg 8 Rm 3143 MS E40, Atlanta, GA, 30329-1902, USA, cwc4@cdc.gov Y1 - 2012/12// PY - 2012 DA - Dec 2012 SP - 518 EP - 529 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 50 IS - 3-4 SN - 0091-0562, 0091-0562 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Acquired immune deficiency syndrome KW - Prevention KW - Human immunodeficiency virus KW - Models KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1434016548?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Community+Psychology&rft.atitle=A+Comparison+of+the+Interactive+Systems+Framework+%28ISF%29+for+Dissemination+and+Implementation+and+the+CDC+Division+of+HIV%2FAIDS+Prevention%27s+Research-to-Practice+Model+for+Behavioral+Interventions&rft.au=Collins%2C+Charles+B%3BEdwards%2C+Arlene+E%3BJones%2C+Patricia+L%3BKay%2C+Linda%3BCox%2C+Pamela+J%3BPuddy%2C+Richard+W&rft.aulast=Collins&rft.aufirst=Charles&rft.date=2012-12-01&rft.volume=50&rft.issue=3-4&rft.spage=518&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Community+Psychology&rft.issn=00910562&rft_id=info:doi/10.1007%2Fs10464-012-9525-7 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-09-01 N1 - Last updated - 2014-03-10 N1 - SubjectsTermNotLitGenreText - Models; Prevention; Human immunodeficiency virus DO - http://dx.doi.org/10.1007/s10464-012-9525-7 ER - TY - JOUR T1 - Lessons from a randomised clinical trial for multidrug-resistant tuberculosis AN - 1285088991; 17493629 AB - BACKGROUND: The treatment of multidrug-resistant tuberculosis (MDR-TB) is currently based upon expert opinion and findings from case series, rather than upon randomised clinical trials (RCTs). OBJECTIVE: To describe the challenges encountered during an RCT for the treatment of MDR-TB. METHODS: Tuberculosis Trials Consortium Study 30 was a pilot, Phase I/II, double-blind, placebo-controlled, RCT of the safety and tolerability of 16 weeks of daily, low-dose linezolid treatment for MDR-TB. RESULTS: A total of 36 patients, 56% of the target of 64 patients, consented to participate, for an average of 0.69 enrolments per week. Of the 36 patients enrolled, only 25 (69%) completed at least 90 doses of study treatment. Among the 12 (33%) patients who did not complete all 112 doses of the study treatment, the median time to study withdrawal was 15 days (range 0-92). After the study, we discovered discordance between treatment assignment and study drug for at least 9 (25%) of the 36 patients. CONCLUSIONS: Recruitment and retention in this MDR-TB clinical trial posed substantial challenges, suggesting the need for a large, multidisciplinary group of study staff to support the participants. Withdrawal tended to occur early in study treatment. The discrepancy in assigned study medication reflects the need for stronger administrative controls for study drugs. JF - International Journal of Tuberculosis and Lung Disease AU - Padayatchi, N AU - Mac Kenzie, WR AU - Hirsch-Moverman, Y AU - Feng, P-J AU - Villarino, E AU - Saukkonen, J AU - Heilig, C M AU - Weiner, M AU - El-Sadr, WM AD - Division of TB Elimination/Centers for Disease Control and Prevention, 1600 Clifton Road, NE, MS E10, Atlanta, GA 30345, USA, wmackenzie@cdc.gov Y1 - 2012/12// PY - 2012 DA - Dec 2012 SP - 1582 EP - 1587 PB - International Union Against Tuberculosis and Lung Disease VL - 16 IS - 12 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology KW - Mycobacterium KW - Drug resistance KW - Discordance KW - Recruitment KW - Lung diseases KW - Tuberculosis KW - Clinical trials KW - Drugs KW - Linezolid KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1285088991?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Lessons+from+a+randomised+clinical+trial+for+multidrug-resistant+tuberculosis&rft.au=Padayatchi%2C+N%3BMac+Kenzie%2C+WR%3BHirsch-Moverman%2C+Y%3BFeng%2C+P-J%3BVillarino%2C+E%3BSaukkonen%2C+J%3BHeilig%2C+C+M%3BWeiner%2C+M%3BEl-Sadr%2C+WM&rft.aulast=Padayatchi&rft.aufirst=N&rft.date=2012-12-01&rft.volume=16&rft.issue=12&rft.spage=1582&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Drug resistance; Recruitment; Discordance; Lung diseases; Tuberculosis; Linezolid; Drugs; Clinical trials; Mycobacterium ER - TY - JOUR T1 - Development of an Influenza Virologic Risk Assessment Tool AN - 1285086936; 17577340 AB - Influenza pandemics pose a continuous risk to human and animal health and may engender food security issues worldwide. As novel influenza A virus infections in humans are identified, pandemic preparedness strategies necessarily involve decisions regarding which viruses should be included for further studies and mitigation efforts. Resource and time limitations dictate that viruses determined to pose the greatest risk to public or animal health should be selected for further research to fill information gaps and, potentially, for development of vaccine candidates that could be put in libraries, manufactured and stockpiled, or even administered to protect susceptible populations of animals or people. A need exists to apply an objective, science-based risk assessment to the process of evaluating influenza viruses. During the past year, the Centers for Disease Control and Prevention began developing a tool to evaluate influenza A viruses that are not circulating in the human population but pose a pandemic risk. The objective is to offer a standardized set of considerations to be applied when evaluating prepandemic viruses. The tool under consideration is a simple, additive model, based on multiattribute decision analysis. The model includes elements that address the properties of the virus itself and population attributes, considers both veterinary and human findings, and integrates both laboratory and field observations. Additionally, each element is assigned a weight such that all elements are not considered of equal importance within the model. JF - Avian Diseases AU - Trock, Susan C AU - Burke, Stephen A AU - Cox, Nancy J AD - Centers for Disease Control and Prevention, Influenza Division, 1600 Clifton Road, Atlanta, GA 30333, sct1@cdc.gov Y1 - 2012/12// PY - 2012 DA - Dec 2012 SP - 1058 EP - 1061 PB - American Association of Avian Pathologists, 382 West Street Road Kennett Sq. PA 19348-1692 United States VL - 56 IS - 4s1 SN - 0005-2086, 0005-2086 KW - Health & Safety Science Abstracts; Risk Abstracts; Virology & AIDS Abstracts KW - Risk assessment KW - Mitigation KW - Influenza A KW - Food KW - Viruses KW - Disease control KW - Infection KW - Models KW - Influenza KW - Prevention KW - pandemics KW - Influenza A virus KW - Standards KW - Vaccines KW - R2 23060:Medical and environmental health KW - H 4000:Food and Drugs KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1285086936?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Avian+Diseases&rft.atitle=Development+of+an+Influenza+Virologic+Risk+Assessment+Tool&rft.au=Trock%2C+Susan+C%3BBurke%2C+Stephen+A%3BCox%2C+Nancy+J&rft.aulast=Trock&rft.aufirst=Susan&rft.date=2012-12-01&rft.volume=56&rft.issue=4s1&rft.spage=1058&rft.isbn=&rft.btitle=&rft.title=Avian+Diseases&rft.issn=00052086&rft_id=info:doi/10.1637%2F10204-041412-ResNote.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-01 N1 - Number of references - 13 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Risk assessment; pandemics; Food; Influenza A; Disease control; Vaccines; Infection; Models; Influenza; Prevention; Mitigation; Viruses; Standards; Influenza A virus DO - http://dx.doi.org/10.1637/10204-041412-ResNote.1 ER - TY - JOUR T1 - Brucellosis Seroprevalence Among Workers in At-Risk Professions: Northwestern Wyoming, 2005 to 2006 AN - 1268652688; 17516394 AB - Objective: Brucellosis is uncommon in the United States; however, its circulation among wildlife and domestic cattle has been ongoing in Wyoming. To assess the public health threat of brucellosis circulation among animals, a seroprevalence study was undertaken among workers in professions considered to be at the highest risk for infection. Methods: A seroprevalence study was undertaken targeting individuals in at-risk professions in the affected area of the state. Results: Seroprevalence among study participants was 14.4%. Veterinarians were the main professional group that demonstrated a statistically significant association with measurable anti-Brucella antibodies. Vaccinating animals with Brucella vaccines was associated with seropositivity. Conclusion: The risk to the general public's health from the circulation of Brucella among wildlife and cattle can be attributed primarily to a limited subpopulation at high risk rather than a generally elevated risk. JF - Journal of Occupational and Environmental Medicine AU - Luce, R AU - Snow, J AU - Gross, D AU - Murphy, T AU - Grandpre, J AU - Daley, W R AU - Brudvig, J M AU - Ari, MD AU - Harris, L AU - Clark, T A AD - Center for Global Health, Centers for Disease Control and Prevention, Global Immunization Division, 1600 Clifton Rd, MS A-05, Atlanta, GA 30333, USA, dwe5@cdc.gov Y1 - 2012/12// PY - 2012 DA - Dec 2012 SP - 1557 EP - 1560 VL - 54 IS - 12 SN - 1076-2752, 1076-2752 KW - Microbiology Abstracts B: Bacteriology; Risk Abstracts; Health & Safety Science Abstracts KW - Antibodies KW - Brucellosis KW - Cattle KW - Infection KW - Public health KW - Risk factors KW - Statistical analysis KW - Subpopulations KW - Vaccines KW - Veterinary medicine KW - Veterinary surgeons KW - Wildlife KW - Workers KW - Brucella KW - USA, Wyoming KW - J 02350:Immunology KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1268652688?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Brucellosis+Seroprevalence+Among+Workers+in+At-Risk+Professions%3A+Northwestern+Wyoming%2C+2005+to+2006&rft.au=Luce%2C+R%3BSnow%2C+J%3BGross%2C+D%3BMurphy%2C+T%3BGrandpre%2C+J%3BDaley%2C+W+R%3BBrudvig%2C+J+M%3BAri%2C+MD%3BHarris%2C+L%3BClark%2C+T+A&rft.aulast=Luce&rft.aufirst=R&rft.date=2012-12-01&rft.volume=54&rft.issue=12&rft.spage=1557&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e31826e27ce LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-01-01 N1 - Last updated - 2013-02-22 N1 - SubjectsTermNotLitGenreText - Workers; Antibodies; Subpopulations; Risk factors; Wildlife; Statistical analysis; Veterinary surgeons; Vaccines; Infection; Brucellosis; Public health; Veterinary medicine; Cattle; Brucella; USA, Wyoming DO - http://dx.doi.org/10.1097/JOM.0b013e31826e27ce ER - TY - JOUR T1 - The Value of Periodic Spirometry for Early Recognition of Long-Term Excessive Lung Function Decline in Individuals AN - 1268652303; 17516386 AB - Objective: To establish the value of workplace spirometry monitoring methods for early recognition of long-term excessive lung function decline in individuals. Methods: Sensitivity, specificity, and positive likelihood ratio were calculated to determine the predictive value of the linear regression slope and limits of longitudinal decline for early prediction of long-term excessive forced expiratory volume in 1 second (FEV sub(1)) decline (> 90 mL/yr established over 9 to 11 years) in ongoing spirometry monitoring programs (firefighters and construction workers) and a historical program (paper-pulp mill workers). The longitudinal limits account for the expected FEV sub(1) within-person variability. Results: The longitudinal limits achieved clinical "usefulness" (positive likelihood ratio 10 or higher) from the fourth to fifth year of follow-up, whereas the linear regression slope was less useful. The usefulness depended on data precision and measurement frequency. Conclusion: The limits of longitudinal decline are more useful for early recognition of long-term excessive FEV sub(1) decline than the linear regression slope. JF - Journal of Occupational and Environmental Medicine AU - Hnizdo, E AD - Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, 1095 Willowdale Rd, Morgantown, WV 26505, USA, ehnizdo@cdc.gov Y1 - 2012/12// PY - 2012 DA - Dec 2012 SP - 1506 EP - 1512 VL - 54 IS - 12 SN - 1076-2752, 1076-2752 KW - Pollution Abstracts; Health & Safety Science Abstracts KW - Prediction KW - Historical account KW - Sensitivity KW - Monitoring methods KW - firefighter services KW - Respiratory function KW - Construction industry KW - H 1000:Occupational Safety and Health KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1268652303?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=The+Value+of+Periodic+Spirometry+for+Early+Recognition+of+Long-Term+Excessive+Lung+Function+Decline+in+Individuals&rft.au=Hnizdo%2C+E&rft.aulast=Hnizdo&rft.aufirst=E&rft.date=2012-12-01&rft.volume=54&rft.issue=12&rft.spage=1506&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e3182664811 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-01-01 N1 - Last updated - 2013-06-28 N1 - SubjectsTermNotLitGenreText - Prediction; Sensitivity; Historical account; Monitoring methods; firefighter services; Respiratory function; Construction industry DO - http://dx.doi.org/10.1097/JOM.0b013e3182664811 ER - TY - JOUR T1 - Occupational exposure to body fluids among health care workers in Georgia AN - 1257745510; 17422526 AB - Background Health care workers (HCWs) are at increased risk of being infected with blood-borne pathogens. Aims To evaluate risk of occupational exposure to blood-borne viruses and determine the prevalence of human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV) among HCWs in Georgia. Methods The sample included HCWs from seven medical institutions in five cities in Georgia. A self-administered questionnaire was used to collect information on demographic, occupational and personal risk factors for blood-borne viruses. After obtaining informed consent, blood was drawn from the study participants for a seroprevalence study of HBV, HCV and HIV infections. Results There were 1386 participating HCWs from a number of departments, including surgery (29%), internal medicine (19%) and intensive care (19%). Nosocomial risk events were reported by the majority of HCWs, including accidental needlestick injury (45%), cuts with contaminated instruments (38%) and blood splashes (46%). The most frequent risk for receiving a cut was related to a false move during a procedure, reassembling devices and handing devices to a colleague. The highest proportion of needlestick injuries among physicians (22%) and nurses (39%) was related to recapping of used needles. No HIV-infected HCW was identified. Prevalence of HCV infection was 5%, anti-HBc was present among 29% with 2% being HBsAg carriers. Conclusions Data from this study can be utilized in educational programs and implementation of universal safety precautions for HCWs in Georgia to help achieve similar reductions in blood-borne infection transmission to those achieved in developed countries. JF - Occupational Medicine AU - Butsashvili, M AU - Kamkamidze, G AU - Kajaia, M AU - Morse, D L AU - Triner, W AU - DeHovitz, J AU - McNutt, L-A AD - super(1)National Center for Disease Control and Public Health Tbilisi, Georgia, maiabutsashvili@gmail.com Y1 - 2012/12// PY - 2012 DA - Dec 2012 SP - 620 EP - 626 PB - Oxford University Press, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 62 IS - 8 SN - 0962-7480, 0962-7480 KW - Toxicology Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - Blood-borne virus KW - contamination injury KW - developing country KW - needlestick KW - Developed countries KW - Injuries KW - Viruses KW - Hepatitis B surface antigen KW - Infection KW - Medical personnel KW - Demography KW - Risk factors KW - Surgery KW - Body fluids KW - Occupational exposure KW - Inventories KW - Data processing KW - Hepatitis B virus KW - USA, Georgia KW - Pathogens KW - Blood KW - Hepatitis C virus KW - Human immunodeficiency virus KW - Hospitals KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1257745510?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Occupational+Medicine&rft.atitle=Occupational+exposure+to+body+fluids+among+health+care+workers+in+Georgia&rft.au=Butsashvili%2C+M%3BKamkamidze%2C+G%3BKajaia%2C+M%3BMorse%2C+D+L%3BTriner%2C+W%3BDeHovitz%2C+J%3BMcNutt%2C+L-A&rft.aulast=Butsashvili&rft.aufirst=M&rft.date=2012-12-01&rft.volume=62&rft.issue=8&rft.spage=620&rft.isbn=&rft.btitle=&rft.title=Occupational+Medicine&rft.issn=09627480&rft_id=info:doi/10.1093%2Foccmed%2Fkqs121 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-12-01 N1 - Last updated - 2014-10-02 N1 - SubjectsTermNotLitGenreText - Inventories; Data processing; Injuries; Hepatitis B surface antigen; Pathogens; Infection; Medical personnel; Demography; Blood; Surgery; Risk factors; Occupational exposure; Body fluids; Hospitals; Developed countries; Human immunodeficiency virus; Viruses; Hepatitis C virus; Hepatitis B virus; USA, Georgia DO - http://dx.doi.org/10.1093/occmed/kqs121 ER - TY - JOUR T1 - Development of a consensus method for culture of Clostridium difficile from meat and its use in a survey of U.S. retail meats AN - 1093476767; 17160725 AB - Three previously described methods for culture of Clostridium difficile from meats were evaluated by microbiologists with experience in C. difficile culture and identification. A consensus protocol using BHI broth enrichment followed by ethanol shock and plating to selective and non-selective media was selected for use, and all participating laboratories received hands-on training in the use of this method prior to study initiation. Retail meat products (N = 1755) were cultured for C. difficile over 12 months during 2010-2011 at 9 U.S. FoodNet sites. No C. difficile was recovered, although other clostridia were isolated. JF - Food Microbiology AU - Limbago, Brandi AU - Thompson, Angela D AU - Greene, Sharon A AU - MacCannell, Duncan AU - MacGowan, Charles E AU - Jolbitado, Beverly AU - Hardin, Henrietta D AU - Estes, Stephanie R AU - Weese, JScott AU - Songer, JGlenn AU - Gould, LHannah AD - Centers for Disease Control and Prevention, Division of Healthcare Quality Promotion, 1600 Clifton Rd. N.E., MS C16, Atlanta, GA 30329, USA, blimbago@cdc.gov Y1 - 2012/12// PY - 2012 DA - Dec 2012 SP - 448 EP - 451 PB - Elsevier B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 32 IS - 2 SN - 0740-0020, 0740-0020 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Ethanol KW - Meat KW - Clostridium difficile KW - J:02300 KW - A:01330 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1093476767?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Food+Microbiology&rft.atitle=Development+of+a+consensus+method+for+culture+of+Clostridium+difficile+from+meat+and+its+use+in+a+survey+of+U.S.+retail+meats&rft.au=Limbago%2C+Brandi%3BThompson%2C+Angela+D%3BGreene%2C+Sharon+A%3BMacCannell%2C+Duncan%3BMacGowan%2C+Charles+E%3BJolbitado%2C+Beverly%3BHardin%2C+Henrietta+D%3BEstes%2C+Stephanie+R%3BWeese%2C+JScott%3BSonger%2C+JGlenn%3BGould%2C+LHannah&rft.aulast=Limbago&rft.aufirst=Brandi&rft.date=2012-12-01&rft.volume=32&rft.issue=2&rft.spage=448&rft.isbn=&rft.btitle=&rft.title=Food+Microbiology&rft.issn=07400020&rft_id=info:doi/10.1016%2Fj.fm.2012.08.005 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-10-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Meat; Clostridium difficile DO - http://dx.doi.org/10.1016/j.fm.2012.08.005 ER - TY - JOUR T1 - Disease surveillance system evaluation as a model for improved integration and standardization of the laboratory component in the Field Epidemiology and Laboratory Training Program (FELTP) curriculum worldwide AN - 1728655508; 2011-358939 AB - Integration of laboratory training into the Centers for Disease Control and Prevention's (CDC) Field Epidemiology Training Program (FETP) began in 2004 and has advanced the training of laboratory scientists worldwide on the basic principles of epidemiology, disease surveillance, and outbreak investigation. The laboratory component of the FE(L)TP training has traditionally been disease specific, revolving around classroom and bench training on laboratory methods, and field placement in areas where services are needed. There is however a need to improve the integration of epidemiology elements used in surveillance, outbreak investigation, and evaluation activities with specific measurable laboratory activities that could in turn impact the overall disease surveillance and response. A systematic and clear evaluation guideline for the laboratory components of disease surveillance systems alongside the corresponding epidemiological indicators can better identify, address, and mitigate weaknesses that may exist in the entire surveillance system, and also help to integrate and standardize the FE(L)TP curriculum content. The institution of laboratory Quality Management System principles linked to a comprehensive surveillance evaluation scheme will result in improved disease surveillance, response, and overall laboratory capacity over time. Adapted from the source document. JF - Journal of Public Health Policy AU - Rush, Thomas AD - South Caucasus Field Epidemiology and Laboratory Training Program (SC/FELTP), NCDC, #9 Asatiani Street 0177, Tbilisi, Georgia trush@cdc.gov Y1 - 2012/11// PY - 2012 DA - November 2012 SP - 390 EP - 400 PB - Palgrave Macmillan, Basingstoke UK VL - 33 IS - 4 SN - 0197-5897, 0197-5897 KW - FE(L)TP, surveillance system evaluation, laboratory indicators, laboratory QMS, laboratory assessment, capacity development KW - Standardization KW - Investigation KW - Scientists KW - Epidemiology KW - Curriculum KW - Laboratories KW - Classrooms KW - Diseases KW - Surveillance KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1728655508?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Public+Health+Policy&rft.atitle=Disease+surveillance+system+evaluation+as+a+model+for+improved+integration+and+standardization+of+the+laboratory+component+in+the+Field+Epidemiology+and+Laboratory+Training+Program+%28FELTP%29+curriculum+worldwide&rft.au=Rush%2C+Thomas&rft.aulast=Rush&rft.aufirst=Thomas&rft.date=2012-11-01&rft.volume=33&rft.issue=4&rft.spage=390&rft.isbn=&rft.btitle=&rft.title=Journal+of+Public+Health+Policy&rft.issn=01975897&rft_id=info:doi/10.1057%2Fjphp.2012.35 LA - English DB - PAIS Index N1 - Date revised - 2015-11-01 N1 - Last updated - 2016-09-28 N1 - CODEN - JPPODK N1 - SubjectsTermNotLitGenreText - Laboratories; Surveillance; Diseases; Epidemiology; Investigation; Curriculum; Classrooms; Scientists; Standardization DO - http://dx.doi.org/10.1057/jphp.2012.35 ER - TY - JOUR T1 - Two Pathogens and One Disease: Detection and Identification of Flea-Borne Rickettsiae in Areas Endemic for Murine Typhus in California AN - 1328515351; 17396387 AB - Results of an environmental assessment conducted in a newly emergent focus of murine typhus in southern California are described. Opossums, Didelphis virginiana Kerr, infested with cat fleas, Ctenocephalides felis Buche, in the suburban area were abundant. Animal and flea specimens were tested for the DNA of two flea-borne rickettsiae, Rickettsia typhi and Rickettsia felis. R. felis was commonly detected in fleas collected throughout this area while R. typhi was found at a much lower prevalence in the vicinity of just 7 of 14 case-patient homes identified. DNA of R. felis, but not R. typhi, was detected in renal, hepatic, and pulmonary tissues of opossums. In contrast, there were no hematologic polymerase chain reaction findings of R. felis or R. typhi in opossums, rats, and cats within the endemic area studied. Our data suggest a significant probability of human exposure to R. felis in the area studied; however, disease caused by this agent is not recognized by the medical community and may be misdiagnosed as murine typhus using nondiscriminatory serologic methods. JF - Journal of Medical Entomology AU - Eremeeva, Marina E AU - Karpathy, Sandor E AU - Krueger, Laura AU - Hayes, Erica K AU - Williams, Ashley M AU - Zaldivar, Yamitzel AU - Bennett, Stephen AU - Cummings, Robert AU - Tilzer, Art AU - Velten, Robert K AU - Kerr, Nelson AU - Dasch, Gregory A AU - Hu, Renjie AD - Rickettsial Zoonoses Branch, Division of Vector-borne Diseases, Vector-Borne Diseases, Mail Stop G-13, CDC, 1600 Clifton Road NE, Atlanta GA 30333., skarpathy@cdc.gov Y1 - 2012/11// PY - 2012 DA - Nov 2012 SP - 1485 EP - 1494 PB - Entomological Society of America, 9301 Annapolis Rd. Lanham MD 20706 United States VL - 49 IS - 6 SN - 0022-2585, 0022-2585 KW - Microbiology Abstracts B: Bacteriology; Entomology Abstracts KW - flea-borne rickettsiosis KW - Rickettsia typhi KW - Rickettsia felis KW - flea KW - opossum KW - Felis KW - Data processing KW - Pathogens KW - Ctenocephalides felis KW - Didelphis virginiana KW - Lung KW - Kidney KW - Liver KW - Polymerase chain reaction KW - Murine typhus KW - J 02410:Animal Diseases KW - Z 05350:Medical, Veterinary, and Agricultural Entomology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1328515351?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Medical+Entomology&rft.atitle=Two+Pathogens+and+One+Disease%3A+Detection+and+Identification+of+Flea-Borne+Rickettsiae+in+Areas+Endemic+for+Murine+Typhus+in+California&rft.au=Eremeeva%2C+Marina+E%3BKarpathy%2C+Sandor+E%3BKrueger%2C+Laura%3BHayes%2C+Erica+K%3BWilliams%2C+Ashley+M%3BZaldivar%2C+Yamitzel%3BBennett%2C+Stephen%3BCummings%2C+Robert%3BTilzer%2C+Art%3BVelten%2C+Robert+K%3BKerr%2C+Nelson%3BDasch%2C+Gregory+A%3BHu%2C+Renjie&rft.aulast=Eremeeva&rft.aufirst=Marina&rft.date=2012-11-01&rft.volume=49&rft.issue=6&rft.spage=1485&rft.isbn=&rft.btitle=&rft.title=Journal+of+Medical+Entomology&rft.issn=00222585&rft_id=info:doi/10.1603%2FME10243 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-04-01 N1 - Number of references - 48 N1 - Last updated - 2015-04-16 N1 - SubjectsTermNotLitGenreText - Data processing; Lung; Liver; Kidney; Polymerase chain reaction; Pathogens; Murine typhus; Ctenocephalides felis; Rickettsia typhi; Felis; Didelphis virginiana; Rickettsia felis DO - http://dx.doi.org/10.1603/ME10243 ER - TY - JOUR T1 - Evaluation of the Infectiousness to Mice of Soil Contaminated with Yersinia pestis-Infected Blood AN - 1323800422; 17718365 AB - Plague, an often-fatal zoonotic disease caused by Yersinia pestis, is characterized by epizootic and quiescent periods. How Y. pestis is maintained during inter-epizootic periods is poorly understood, but soil has been implicated as a potential reservoir. Although previous studies have suggested that Y. pestis is able to survive in soil for weeks or months, it is unclear whether or not it is infectious to susceptible hosts. Here we investigate the potential for Y. pestis to infect mice through close contact with contaminated soil under laboratory conditions. In an attempt to approximate the natural conditions under which animals would be exposed to Y. pestis-contaminated soil, mouse cages rilled with soil from a plague-endemic region were held at temperature and humidity ranges observed in ground squirrel burrows. These laboratory "burrows" were contaminated with highly bacteremic blood (>10 super(8) cfu/mL) to simulate the introduction of infectious material from a dying animal during an epizootic. Outbred Swiss-Webster mice with scarified skin patches were held on contaminated soil for 10 days and monitored for signs of illness. Following exposure to contaminated soil, one animal of 104 became infected with Y. pestis. None of the remaining animals seroconverted following a 21-day holding period. Under our experimental conditions, which maximized the likelihood of contact between susceptible mice and contaminated soil, transmission efficiency from soil to mice was 0.96% (95% CI 0.17, 5.25%). This suggests that although transmission of Y. pestis from contaminated soils is possible, it is not likely a major transmission route under natural conditions. JF - Vector Borne and Zoonotic Diseases AU - Boegler, KA AU - Graham, C B AU - Montenieri, JA AU - MacMillan, K AU - Holmes, J L AU - Petersen, J M AU - Gage, K L AU - Eisen, R J AD - Centers for Disease Control and Prevention, Division of Vector-Borne Infectious Diseases, Bacterial Diseases Branch, 3150 Rampart Road, MS-P02, Fort Collins, CO 80521, USA, kje5@cdc.gov Y1 - 2012/11// PY - 2012 DA - Nov 2012 SP - 948 EP - 952 VL - 12 IS - 11 SN - 1530-3667, 1530-3667 KW - Microbiology Abstracts B: Bacteriology KW - Blood KW - Soil pollution KW - Spermophilus KW - J:02410 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1323800422?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vector+Borne+and+Zoonotic+Diseases&rft.atitle=Evaluation+of+the+Infectiousness+to+Mice+of+Soil+Contaminated+with+Yersinia+pestis-Infected+Blood&rft.au=Boegler%2C+KA%3BGraham%2C+C+B%3BMontenieri%2C+JA%3BMacMillan%2C+K%3BHolmes%2C+J+L%3BPetersen%2C+J+M%3BGage%2C+K+L%3BEisen%2C+R+J&rft.aulast=Boegler&rft.aufirst=KA&rft.date=2012-11-01&rft.volume=12&rft.issue=11&rft.spage=948&rft.isbn=&rft.btitle=&rft.title=Vector+Borne+and+Zoonotic+Diseases&rft.issn=15303667&rft_id=info:doi/10.1089%2Fvbz.2012.1031 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-04-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Soil pollution; Spermophilus DO - http://dx.doi.org/10.1089/vbz.2012.1031 ER - TY - JOUR T1 - Associations of Long-term Shift Work with Waking Salivary Cortisol Concentration and Patterns among Police Officers AN - 1268655682; 17516366 AB - The objective of this study was to evaluate whether long-term shift work is associated with both the total hormonal secretion after awakening and the pattern of the cortisol levels during the first hour following awakening, among 65 randomly selected police officers who represent a high stress occupation. Dominant shift (Day, Afternoon, or Midnight) was ascertained using daily payroll records of each participant's work activities during the 6-8 yrs prior to saliva sampling. Four salivary samples were collected at 15 min intervals upon first awakening. After accounting for potential confounders, salivary cortisol concentrations averaged across all four time points and total area under the curve differed significantly across shift with midnight shift workers showing suppressed awakening cortisol response relative to the afternoon and day shift. The percent of hours worked on midnight shift was inversely correlated with total awakening cortisol output. In contrast, the pattern of cortisol secretion during the first hour following waking appeared not to be affected as no significant interaction effect was found between time since awakening and shift work. The results show that long-term midnight shift work is associated with decreased absolute mean level and total volume of cortisol released over the waking period. JF - Industrial Health AU - Fekedulegn, D AU - Burchfiel, C M AU - Violanti, J M AU - Hartley, T A AU - Charles, LE AU - Andrew, ME AU - Miller, D B AD - Biostatistics and Epidemiology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, USA, djf7@cdc.gov Y1 - 2012/11// PY - 2012 DA - Nov 2012 SP - 476 EP - 486 VL - 50 IS - 6 SN - 0019-8366, 0019-8366 KW - Health & Safety Science Abstracts KW - Shift work KW - Stress KW - Police KW - Working conditions KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1268655682?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Industrial+Health&rft.atitle=Associations+of+Long-term+Shift+Work+with+Waking+Salivary+Cortisol+Concentration+and+Patterns+among+Police+Officers&rft.au=Fekedulegn%2C+D%3BBurchfiel%2C+C+M%3BViolanti%2C+J+M%3BHartley%2C+T+A%3BCharles%2C+LE%3BAndrew%2C+ME%3BMiller%2C+D+B&rft.aulast=Fekedulegn&rft.aufirst=D&rft.date=2012-11-01&rft.volume=50&rft.issue=6&rft.spage=476&rft.isbn=&rft.btitle=&rft.title=Industrial+Health&rft.issn=00198366&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-01-01 N1 - Last updated - 2013-06-28 N1 - SubjectsTermNotLitGenreText - Shift work; Stress; Police; Working conditions ER - TY - JOUR T1 - Parental Occupational Exposures and Autism Spectrum Disorder AN - 1125237726; 17320324 AB - Both self-report and industrial hygienist (IH) assessed parental occupational information were used in this pilot study in which 174 families (93 children with ASD and 81 unaffected children) enrolled in the Childhood Autism Risks from Genetics and Environment study participated. IH results indicated exposures to lacquer, varnish, and xylene occurred more often in the parents of children with ASD compared to the parents of unaffected children. Parents of children with ASD were more likely to report exposures to asphalt and solvents compared to parents of unaffected children. This study was limited by the small sample size, but results suggest that workplace exposures to some chemicals may be important in the etiology of ASD and deserve further investigation. JF - Journal of Autism and Developmental Disorders AU - McCanlies, Erin C AU - Fekedulegn, Desta AU - Mnatsakanova, Anna AU - Burchfiel, Cecil M AU - Sanderson, Wayne T AU - Charles, Luenda E AU - Hertz-Picciotto, Irva AD - National Institute for Occupational Safety and Health, MS: L4050, 1095 Willowdale Rd., Morgantown, WV, 26505, USA, Eim4@cdc.gov Y1 - 2012/11// PY - 2012 DA - Nov 2012 SP - 2323 EP - 2334 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 42 IS - 11 SN - 0162-3257, 0162-3257 KW - CSA Neurosciences Abstracts; Health & Safety Science Abstracts KW - Indexing in process UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1125237726?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Autism+and+Developmental+Disorders&rft.atitle=Parental+Occupational+Exposures+and+Autism+Spectrum+Disorder&rft.au=McCanlies%2C+Erin+C%3BFekedulegn%2C+Desta%3BMnatsakanova%2C+Anna%3BBurchfiel%2C+Cecil+M%3BSanderson%2C+Wayne+T%3BCharles%2C+Luenda+E%3BHertz-Picciotto%2C+Irva&rft.aulast=McCanlies&rft.aufirst=Erin&rft.date=2012-11-01&rft.volume=42&rft.issue=11&rft.spage=2323&rft.isbn=&rft.btitle=&rft.title=Journal+of+Autism+and+Developmental+Disorders&rft.issn=01623257&rft_id=info:doi/10.1007%2Fs10803-012-1468-1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-10-01 N1 - Last updated - 2012-11-02 DO - http://dx.doi.org/10.1007/s10803-012-1468-1 ER - TY - JOUR T1 - Simultaneous analysis of 28 urinary VOC metabolites using ultra high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry (UPLC-ESI/MSMS) AN - 1349465919; 17906177 AB - Volatile organic compounds (VOCs) are ubiquitous in the environment, originating from many different natural and anthropogenic sources, including tobacco smoke. Long-term exposure to certain VOCs may increase the risk for cancer, birth defects, and neurocognitive impairment. Therefore, VOC exposure is an area of significant public health concern. Urinary VOC metabolites are useful biomarkers for assessing VOC exposure because of non-invasiveness of sampling and longer physiological half-lives of urinary metabolites compared with VOCs in blood and breath. We developed a method using reversed-phase ultra high performance liquid chromatography (UPLC) coupled with electrospray ionization tandem mass spectrometry (ESI/MSMS) to simultaneously quantify 28 urinary VOC metabolites as biomarkers of exposure. We describe a method that monitors metabolites of acrolein, acrylamide, acrylonitrile, benzene, 1-bromopropane, 1,3-butadiene, carbon-disulfide, crotonaldehyde, cyanide, N,N-dimethylformamide, ethylbenzene, ethylene oxide, propylene oxide, styrene, tetrachloroethylene, toluene, trichloroethylene, vinyl chloride and xylene. The method is accurate (mean accuracy for spiked matrix ranged from 84 to 104%), sensitive (limit of detection ranged from 0.5 to 20 ng mL(-1)) and precise (the relative standard deviations ranged from 2.5 to 11%). We applied this method to urine samples collected from 1203 non-smokers and 347 smokers and demonstrated that smokers have significantly elevated levels of tobacco-related biomarkers compared to non-smokers. We found significant (p<0.0001) correlations between serum cotinine and most of the tobacco-related biomarkers measured. These findings confirm that this method can effectively quantify urinary VOC metabolites in a population exposed to volatile organics. JF - Analytica Chimica Acta AU - Udeni Alwis, K AU - Blount, Benjamin C AU - Britt, April S AU - Patel, Dhrusti AU - Ashley, David L AD - National Center for Environmental Health, Division of Laboratory Sciences, Centers for Disease Control and Prevention, Atlanta, GA 30341, United States, UAlwis@cdc.gov Y1 - 2012/10/31/ PY - 2012 DA - 2012 Oct 31 SP - 152 EP - 160 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 750 SN - 0003-2670, 0003-2670 KW - Health & Safety Science Abstracts; Pollution Abstracts; Environment Abstracts; Meteorological & Geoastrophysical Abstracts KW - Bioindicators KW - Chromatography KW - Physiology KW - Correlations KW - Mass spectrometry KW - Metabolites KW - Cancer KW - Smoke KW - Urine KW - Liquid chromatography KW - Atmospheric pollution and health KW - Volatile organic compound emission by motor vehicles KW - Tobacco smoke KW - Trichloroethylene KW - Ionization KW - Volatile organic compounds KW - M2 551.510.42:Air Pollution (551.510.42) KW - H 11000:Diseases/Injuries/Trauma KW - P 6000:TOXICOLOGY AND HEALTH KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1349465919?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytica+Chimica+Acta&rft.atitle=Simultaneous+analysis+of+28+urinary+VOC+metabolites+using+ultra+high+performance+liquid+chromatography+coupled+with+electrospray+ionization+tandem+mass+spectrometry+%28UPLC-ESI%2FMSMS%29&rft.au=Udeni+Alwis%2C+K%3BBlount%2C+Benjamin+C%3BBritt%2C+April+S%3BPatel%2C+Dhrusti%3BAshley%2C+David+L&rft.aulast=Udeni+Alwis&rft.aufirst=K&rft.date=2012-10-31&rft.volume=750&rft.issue=&rft.spage=152&rft.isbn=&rft.btitle=&rft.title=Analytica+Chimica+Acta&rft.issn=00032670&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-05-01 N1 - Number of references - 46 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Chromatography; Atmospheric pollution and health; Volatile organic compound emission by motor vehicles; Tobacco smoke; Correlations; Mass spectrometry; Ionization; Smoke; Bioindicators; Liquid chromatography; Urine; Physiology; Metabolites; Trichloroethylene; Cancer; Volatile organic compounds ER - TY - JOUR T1 - Effectiveness of 1 Dose of Influenza A (H1N1) 2009 Monovalent Vaccines in Preventing Reverse-Transcription Polymerase Chain Reaction-Confirmed H1N1 Infection Among School-Aged Children in Maine AN - 1642623797; 20900035 AB - Background. In late October 2009, school-located pandemic vaccination was initiated in Maine before or concurrent with 2009 pandemic influenza A (H1N1) virus (pH1N1) peak activity. Methods. A case-control evaluation of 2009 H1N1 vaccine effectiveness was conducted in schools in Cumberland County, Maine. A case was a child who had an acute respiratory illness during 2 November-18 December 2009, and who tested positive for pH1N1 by real-time reverse-transcription polymerase chain reaction (rRT-PCR). For each case, > or =4 event time-matched controls were sampled among classmates present in school during the study period who did not have an influenza-like illness. Vaccine effectiveness was calculated as (1 - adjusted odds ratio [aOR]) x 100%; aOR was estimated by using weighted logistic regression. Results. After adjusting for a diagnosis of asthma, 1 dose of 2009 H1N1 vaccine provided 69% protection (95% confidence interval (CI), 13-89) against rRT-PCR-confirmed H1N1 infection. Vaccine effectiveness estimates for live attenuated and inactivated vaccine were 81% (95% CI, -37 to 97), and 58% (95% CI: -39 to 87), respectively. Conclusions. One dose of monovalent pandemic vaccine provided substantial protection against pH1N1 infection among school-aged children. JF - Journal of Infectious Diseases AU - Uzicanin, Amra AU - Thompson, Mark AU - Smith, Peter AU - Chaves, Sandra S AU - Foster, Lydia AU - Dube, Nancy AU - Graitcer, Samuel AU - Jackson, Rebel AU - Ferdinands, Jill AU - Gargiullo, Paul AU - Mills, Dora AU - Monto, Arnold S AU - Shay, David K AD - Division of Global Migration and Quarantine; Centers for Disease Control and Prevention, 1600 Clifton Rd, MS E-03, Atlanta, Georgia 30333, aau5@cdc.gov Y1 - 2012/10/01/ PY - 2012 DA - 2012 Oct 01 SP - 1059 EP - 1068 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 206 IS - 7 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Influenza A KW - Asthma KW - Respiratory diseases KW - Infection KW - Children KW - Influenza KW - pandemics KW - Schools KW - Infectious diseases KW - Polymerase chain reaction KW - USA, Maine KW - Vaccines KW - H 1000:Occupational Safety and Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1642623797?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Effectiveness+of+1+Dose+of+Influenza+A+%28H1N1%29+2009+Monovalent+Vaccines+in+Preventing+Reverse-Transcription+Polymerase+Chain+Reaction-Confirmed+H1N1+Infection+Among+School-Aged+Children+in+Maine&rft.au=Uzicanin%2C+Amra%3BThompson%2C+Mark%3BSmith%2C+Peter%3BChaves%2C+Sandra+S%3BFoster%2C+Lydia%3BDube%2C+Nancy%3BGraitcer%2C+Samuel%3BJackson%2C+Rebel%3BFerdinands%2C+Jill%3BGargiullo%2C+Paul%3BMills%2C+Dora%3BMonto%2C+Arnold+S%3BShay%2C+David+K&rft.aulast=Uzicanin&rft.aufirst=Amra&rft.date=2012-10-01&rft.volume=206&rft.issue=7&rft.spage=1059&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjis441 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - pandemics; Influenza A; Polymerase chain reaction; Asthma; Vaccines; Children; Infection; Influenza; Schools; Infectious diseases; Respiratory diseases; USA, Maine DO - http://dx.doi.org/10.1093/infdis/jis441 ER - TY - JOUR T1 - Pediatric Primary Care Physicians' Practices Regarding Newborn Hearing Screening AN - 1373477959; 201310538 AB - Objective: Approximately 2 to 3 out of 1000 infants are born with hearing loss in the United States each year. Pediatric primary care physicians (PCPs) can play an important role in ensuring that infants with hearing loss are identified early and provided appropriate services. In this study, pediatric PCPs were surveyed about their practices regarding early hearing detection and intervention. Methods: Responses from the 2008 DocStyles survey were used to examine patient, physician, and practice variables associated with actions consistent with the 2007 Joint Committee on Infant Hearing position statement, which includes follow-up protocols for medical home providers. Results: Pediatricians working in a group setting were more likely to receive hearing screening results than were those in individual practices or hospitals and clinics. Family/general physicians with heavier caseloads were more likely to receive hearing screening results for their pediatric patients than were those with lighter caseloads. Few pediatric PCPs reported contacting their state's early hearing detection and intervention program if they knew that an infant failed the newborn hearing screening. Although high proportions of pediatric PCPs reported referring an infant with hearing loss to an otolaryngologist, only about half reported referring a child with risk factors for hearing loss for audiological and speech-language assessment, even if the parents expressed concern or if the results of a developmental screening indicated a possible delay. Few respondents reported referring an infant with hearing loss under their care to an ophthalmologist. Conclusions: This study highlights the need to improve infrastructure for pediatric PCPs to receive and request infant hearing screening results to facilitate reporting and coordinate follow-up services for infants identified with hearing loss. [Reprinted by permission of Sage Publications Inc., copyright holder.] JF - Journal of Primary Care & Community Health AU - Ross, Danielle S AU - Visser, Susanna N AD - Centers for Disease Control and Prevention, Atlanta, Georgia ayu0@cdc.gov Y1 - 2012/10// PY - 2012 DA - October 2012 SP - 256 EP - 263 VL - 3 IS - 4 SN - 2150-1319, 2150-1319 KW - Infants (35660) KW - Audiometry (05600) KW - Diagnostic Tests (18550) KW - Hearing Disorders (31450) KW - article KW - 6310: hearing-pathological and normal; hearing-pathological and normal UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1373477959?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Allba&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Primary+Care+%26+Community+Health&rft.atitle=Pediatric+Primary+Care+Physicians%27+Practices+Regarding+Newborn+Hearing+Screening&rft.au=Ross%2C+Danielle+S%3BVisser%2C+Susanna+N&rft.aulast=Ross&rft.aufirst=Danielle&rft.date=2012-10-01&rft.volume=3&rft.issue=4&rft.spage=256&rft.isbn=&rft.btitle=&rft.title=Journal+of+Primary+Care+%26+Community+Health&rft.issn=21501319&rft_id=info:doi/ LA - English DB - Linguistics and Language Behavior Abstracts (LLBA) N1 - Date revised - 2013-07-01 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Hearing Disorders (31450); Audiometry (05600); Infants (35660); Diagnostic Tests (18550) ER - TY - JOUR T1 - Impact of a Hygiene Curriculum and the Installation of Simple Handwashing and Drinking Water Stations in Rural Kenyan Primary Schools on Student Health and Hygiene Practices AN - 1238120369; 17411323 AB - School-based hygiene and water treatment programs increase student knowledge, improve hygiene, and decrease absenteeism, however health impact studies of these programs are lacking. We collected baseline information from students in 42 schools in Kenya. We then instituted a curriculum on safe water and hand hygiene and installed water stations in half ("intervention schools"). One year later, we implemented the intervention in remaining schools. Through biweekly student household visits and two annual surveys, we compared the effect of the intervention on hygiene practices and reported student illness. We saw improvement in proper handwashing techniques after the school program was introduced. We observed a decrease in the median percentage of students with acute respiratory illness among those exposed to the program; no decrease in acute diarrhea was seen. Students in this school program exhibited sustained improvement in hygiene knowledge and a decreased risk of respiratory infections after the intervention. JF - American Journal of Tropical Medicine and Hygiene AU - Patel, M K AU - Harris, J R AU - Juliao, P AU - Nygren, B AU - Were, V AU - Kola, S AU - Sadumah, I AU - Faith, SH AU - Otieno, R AU - Obure, A AU - Hoekstra, R M AU - Quick, R AD - Global Immunization Division, Centers for Disease Control and Prevention, 1600 Clifton Road, MS A04, Atlanta, CA 30333, USA, hgo9@cdc.gov Y1 - 2012/10// PY - 2012 DA - October 2012 SP - 594 EP - 601 VL - 87 IS - 4 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts; Pollution Abstracts; Risk Abstracts; Aqualine Abstracts; Water Resources Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality KW - Respiration KW - Intervention KW - Infection KW - Kenya KW - Drinking Water KW - Water treatment KW - Water Treatment KW - Diarrhea KW - Surveys KW - Hand KW - Education establishments KW - Installation KW - Risk KW - Education KW - Schools KW - Households KW - Drinking water KW - Hygiene KW - Metabolism KW - Rural areas KW - SW 5010:Network design KW - P 2000:FRESHWATER POLLUTION KW - K 03400:Human Diseases KW - AQ 00008:Effects of Pollution KW - J 02400:Human Diseases KW - H 1000:Occupational Safety and Health KW - R2 23060:Medical and environmental health KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1238120369?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Impact+of+a+Hygiene+Curriculum+and+the+Installation+of+Simple+Handwashing+and+Drinking+Water+Stations+in+Rural+Kenyan+Primary+Schools+on+Student+Health+and+Hygiene+Practices&rft.au=Patel%2C+M+K%3BHarris%2C+J+R%3BJuliao%2C+P%3BNygren%2C+B%3BWere%2C+V%3BKola%2C+S%3BSadumah%2C+I%3BFaith%2C+SH%3BOtieno%2C+R%3BObure%2C+A%3BHoekstra%2C+R+M%3BQuick%2C+R&rft.aulast=Patel&rft.aufirst=M&rft.date=2012-10-01&rft.volume=87&rft.issue=4&rft.spage=594&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.2012.11-0494 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-12-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Education; Drinking Water; Water treatment; Respiration; Hygiene; Education establishments; Metabolism; Diarrhea; Hand; Drinking water; Infection; Schools; Households; Intervention; Rural areas; Risk; Surveys; Water Treatment; Installation; Kenya DO - http://dx.doi.org/10.4269/ajtmh.2012.11-0494 ER - TY - JOUR T1 - Tuberculosis caused by RD super(Rio) Mycobacterium tuberculosis is not associated with differential clinical features AN - 1171899813; 17342662 AB - BACKGROUND: We recently described the Mycobacterium tuberculosis RD super(Rio) genotype, a clonally derived sublineage within the Latin American-Mediterranean (LAM) family. Genetic diversity of M. tuberculosis likely affects the clinical aspects of tuberculosis (TB). Prospective studies that address this issue are scarce and remain controversial. OBJECTIVE: To determine the association of differential clinical features of pulmonary TB with the RD super(Rio) M. tuberculosis etiology. METHODS: Culture-proven pulmonary TB patients (n = 272) were clinically evaluated, including history, physical examination, chest X-ray and anti-human immunodeficiency virus serology. Isolates were classified as RD super(Rio) or non-RD super(Rio) M. tuberculosis by multiplex polymerase chain reaction and further spoligotyped. Clinical and M. tuberculosis genotype data were analyzed. RESULTS: RD super(Rio) M. tuberculosis caused disease in 26.5% (72/270) of all TB cases. The LAM genotype, of which RD super(Rio) strains are members, was responsible for 46.0% of the TB cases. Demographic data, major signs and symptoms, radiographic presentation, microbiological features and clinical outcomes were not significantly different among patients with TB caused by RD super(Rio) and non-RD super(Rio) strains. CONCLUSIONS: Disease caused by M. tuberculosis RD super(Rio) strains was not clinically distinctive or more severe than disease caused by non-RD super(Rio) strains in this series of TB patients. Larger prospective studies specifically designed to disclose differential clinical characteristics of TB caused by specific M. tuberculosis lineages are needed. JF - International Journal of Tuberculosis and Lung Disease AU - de B Barbosa, C AU - Lazzarini, LCO AU - Elias, A R AU - Leung, JAM AU - Ribeiro, S B AU - da Silva, MG AU - Duarte, R S AU - Suffys, P AU - Gomes, H M AU - Kritski, AL AU - Silva, JRLE AU - Ho, J L AU - Boechat, N AD - Medical Affairs Section, Centers for Disease Control in Haiti, Dulles, VA 20189, USA, hoj@ht.cdc.gov Y1 - 2012/10// PY - 2012 DA - Oct 2012 SP - 1377 EP - 1382 PB - International Union Against Tuberculosis and Lung Disease VL - 16 IS - 10 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology KW - Etiology KW - Data processing KW - Lung diseases KW - Genetic diversity KW - Genotypes KW - Clinical aspects KW - Chest KW - Serology KW - Demography KW - Ionizing radiation KW - Polymerase chain reaction KW - Tuberculosis KW - Mycobacterium tuberculosis KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1171899813?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Tuberculosis+caused+by+RD+super%28Rio%29+Mycobacterium+tuberculosis+is+not+associated+with+differential+clinical+features&rft.au=de+B+Barbosa%2C+C%3BLazzarini%2C+LCO%3BElias%2C+A+R%3BLeung%2C+JAM%3BRibeiro%2C+S+B%3Bda+Silva%2C+MG%3BDuarte%2C+R+S%3BSuffys%2C+P%3BGomes%2C+H+M%3BKritski%2C+AL%3BSilva%2C+JRLE%3BHo%2C+J+L%3BBoechat%2C+N&rft.aulast=de+B+Barbosa&rft.aufirst=C&rft.date=2012-10-01&rft.volume=16&rft.issue=10&rft.spage=1377&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-11-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Demography; Etiology; Data processing; Ionizing radiation; Lung diseases; Polymerase chain reaction; Genetic diversity; Tuberculosis; Genotypes; Chest; Clinical aspects; Serology; Mycobacterium tuberculosis ER - TY - JOUR T1 - Predictors of sputum culture conversion among patients treated for multidrug-resistant tuberculosis AN - 1171895912; 17342655 AB - OBJECTIVE: To identify predictors of initial sputum culture conversion, estimate the usefulness of persistent positive cultures at different time points in predicting treatment failure, and evaluate different definitions of culture conversion for predicting failure among patients with multidrug-resistant tuberculosis (MDR-TB) in five countries, 2000-2004. METHODS: Predictors of time to conversion were identified using multivariate Cox proportional hazards regression modeling. Receiver operating characteristic curves were plotted to visualize the effect of using different definitions of 'culture conversion' on the balance between sensitivity and specificity. RESULTS: Overall, 1209/1416 (85%) of patients with baseline positive cultures converted in a median of 3.0 months (interquartile range 2.0-5.0). Independent predictors of less likely conversion included baseline positive smear (hazard ratio [HR] 0.60, 95%CI 0.53-0.68), resistance to pyrazinamide (HR 0.82, 95%CI 0.70-0.96), fluoroquinolones (FQs; HR 0.65, 95%CI 0.51-0.83) or thioamide (HR 0.83, 95%CI 0.71-0.96), previous use of FQs (HR 0.71, 95%CI 0.60-0.83), poor outcome of previous anti-tuberculosis treatment (HR 0.69, 95%CI 0.54-0.88) and alcoholism (HR 0.74, 95%CI 0.63-0.87). The maximum combined sensitivity (84%) and specificity (94%) in predicting treatment failure was based on lack of culture conversion at month 9 of treatment, assuming conversion is defined as five consecutive negative cultures. CONCLUSION: Patients with identified risk factors were less likely to achieve sputum culture conversion during MDR-TB treatment. JF - International Journal of Tuberculosis and Lung Disease AU - Kurbatova, E V AU - Gammino, V M AU - Bayona, J AU - Becerra, M C AU - Danilovitz, M AU - Falzon, D AU - Gelmanova, I AU - Keshavjee, S AU - Leimane, V AU - Mitnick, C D AU - Quelapio, MI AU - Riekstina, V AU - Taylor, A AU - Viiklepp, P AD - International Research and Programs Branch, Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, Mailstop E-10, NE, 1600 Clifton Road, Atlanta, GA 30333, USA, ekurbatova@cdc.gov Y1 - 2012/10// PY - 2012 DA - Oct 2012 SP - 1335 EP - 1343 PB - International Union Against Tuberculosis and Lung Disease VL - 16 IS - 10 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology; Risk Abstracts KW - Sensitivity KW - Fluoroquinolones KW - Mycobacterium KW - Drug resistance KW - Lung diseases KW - Drug abuse KW - Lung KW - Risk factors KW - Alcoholism KW - Tuberculosis KW - pyrazinamide KW - Sputum KW - R2 23060:Medical and environmental health KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1171895912?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Predictors+of+sputum+culture+conversion+among+patients+treated+for+multidrug-resistant+tuberculosis&rft.au=Kurbatova%2C+E+V%3BGammino%2C+V+M%3BBayona%2C+J%3BBecerra%2C+M+C%3BDanilovitz%2C+M%3BFalzon%2C+D%3BGelmanova%2C+I%3BKeshavjee%2C+S%3BLeimane%2C+V%3BMitnick%2C+C+D%3BQuelapio%2C+MI%3BRiekstina%2C+V%3BTaylor%2C+A%3BViiklepp%2C+P&rft.aulast=Kurbatova&rft.aufirst=E&rft.date=2012-10-01&rft.volume=16&rft.issue=10&rft.spage=1335&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-11-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Fluoroquinolones; Risk factors; Drug resistance; Alcoholism; Lung diseases; pyrazinamide; Tuberculosis; Sputum; Drug abuse; Sensitivity; Lung; Mycobacterium ER - TY - JOUR T1 - 2011: The year in review. Part II: Tuberculosis and lung disease AN - 1171870644; 17342648 AB - IN THIS YEAR-IN-REVIEW ARTICLE, we review 52 of 55 articles published on tuberculosis (TB) in the International Journal of Tuberculosis and Lung Disease from August through December 2011, complementing the 104 summarized by Chang and Nuermberger, super(1) and using the same categories (Table 1). We also summarize 33 of 36 non-TB articles for the entire year (Table 2). JF - International Journal of Tuberculosis and Lung Disease AU - Iademarco, M F AU - Koh, W J AD - Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, GA, USA, mai9@cdc.gov Y1 - 2012/10// PY - 2012 DA - Oct 2012 SP - 1291 EP - 1299 PB - International Union Against Tuberculosis and Lung Disease VL - 16 IS - 10 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology KW - Mycobacterium KW - Reviews KW - Lung diseases KW - Tuberculosis KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1171870644?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=2011%3A+The+year+in+review.+Part+II%3A+Tuberculosis+and+lung+disease&rft.au=Iademarco%2C+M+F%3BKoh%2C+W+J&rft.aulast=Iademarco&rft.aufirst=M&rft.date=2012-10-01&rft.volume=16&rft.issue=10&rft.spage=1291&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-11-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Reviews; Lung diseases; Tuberculosis; Mycobacterium ER - TY - JOUR T1 - Impact of second-line drug resistance on tuberculosis treatment outcomes in the United States: MDR-TB is bad enough AN - 1171868967; 17342654 AB - SETTING: The worldwide emergence of extensively drug-resistant tuberculosis (TB) has focused attention on treatment with second-line drugs (SLDs). OBJECTIVE: To determine the impact on outcomes of resistance to individual SLDs, we analyzed successful treatment completion and death among drug-resistant TB cases in the US national TB surveillance system, 1993-2007 (N = 195 518). DESIGN: We defined four combinations of first-line drug (FLD) resistance based on isoniazid (INH) and rifamycin, and three patterns of SLD resistance: fluoroquinolones, injectable SLDs and other oral SLDs. We compared treatment outcomes of cases by FLD resistance, with and without each pattern of SLD resistance. RESULTS: In all but one instance, cases with FLD resistance but no SLD resistance had better outcomes than cases with SLD resistance. Rifamycin resistance, alone or with INH, resulted in a greater decline in treatment completion and greater increase in deaths than resistance to SLDs. Among patients with multidrug-resistant TB, additional resistance to injectable SLDs was statistically significant. Outcomes were better for human immunodeficiency virus (HIV) negative than HIV-positive cases for all resistance patterns, but improved among HIV-infected cases after 1998, when highly active antiretroviral treatment became widely available. CONCLUSION: These results suggest that the effect of rifamycin resistance may outweigh the more modest effects of resistance to specific SLDs. JF - International Journal of Tuberculosis and Lung Disease AU - Althomsons, S P AU - Cegielski, J P AD - Surveillance, Epidemiology, Outbreak Investigations Branch, Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, Mailstop E-10, 1600 Clifton Road NE, Atlanta, GA 30333, USA, SAlthomsons@cdc.gov Y1 - 2012/10// PY - 2012 DA - Oct 2012 SP - 1331 EP - 1334 PB - International Union Against Tuberculosis and Lung Disease VL - 16 IS - 10 SN - 1027-3719, 1027-3719 KW - Virology & AIDS Abstracts; Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts KW - Antiretroviral agents KW - USA KW - Human immunodeficiency virus KW - Tuberculosis KW - V:22360 KW - J:02400 KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1171868967?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Impact+of+second-line+drug+resistance+on+tuberculosis+treatment+outcomes+in+the+United+States%3A+MDR-TB+is+bad+enough&rft.au=Althomsons%2C+S+P%3BCegielski%2C+J+P&rft.aulast=Althomsons&rft.aufirst=S&rft.date=2012-10-01&rft.volume=16&rft.issue=10&rft.spage=1331&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-11-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Tuberculosis; Human immunodeficiency virus; USA ER - TY - JOUR T1 - Molecular basis of electrophilic and oxidative defense: promises and perils of Nrf2. AN - 1081875900; 22966037 AB - Induction of drug-metabolizing enzymes through the antioxidant response element (ARE)-dependent transcription was initially implicated in chemoprevention against cancer by antioxidants. Recent progress in understanding the biology and mechanism of induction revealed a critical role of induction in cellular defense against electrophilic and oxidative stress. Induction is mediated through a novel signaling pathway via two regulatory proteins, the nuclear factor erythroid 2-related factor 2 (Nrf2) and the Kelch-like erythroid cell-derived protein with CNC homology-associated protein 1 (Keap1). Nrf2 binds to Keap1 at a two site-binding interface and is ubiquitinated by the Keap1/cullin 3/ring box protein-1-ubiquitin ligase, resulting in a rapid turnover of Nrf2 protein. Electrophiles and oxidants modify critical cysteine thiols of Keap1 and Nrf2 to inhibit Nrf2 ubiquitination, leading to Nrf2 activation and induction. Induction increases stress resistance critical for cell survival, because knockout of Nrf2 in mice increased susceptibility to a variety of toxicity and disease processes. Collateral to diverse functions of Nrf2, genome-wide search has led to the identification of a plethora of ARE-dependent genes regulated by Nrf2 in an inducer-, tissue-, and disease-dependent manner to control drug metabolism, antioxidant defense, stress response, proteasomal degradation, and cell proliferation. The protective nature of Nrf2 could also be hijacked in a number of pathological conditions by means of somatic mutation, epigenetic alteration, and accumulation of disruptor proteins, promoting drug resistance in cancer and pathologic liver features in autophagy deficiency. The repertoire of ARE inducers has expanded enormously; the therapeutic potential of the inducers has been examined beyond cancer prevention. Developing potent and specific ARE inducers and Nrf2 inhibitors holds certain new promise for the prevention and therapy against cancer, chronic disease, and toxicity. JF - Pharmacological reviews AU - Ma, Qiang AU - He, Xiaoqing AD - Receptor Biology Laboratory, Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, National Institute forOccupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia. qam1@cdc.gov Y1 - 2012/10// PY - 2012 DA - October 2012 SP - 1055 EP - 1081 VL - 64 IS - 4 KW - NF-E2-Related Factor 2 KW - 0 KW - Index Medicus KW - Animals KW - Humans KW - Mutation KW - Neoplasms -- genetics KW - Neoplasms -- metabolism KW - NF-E2-Related Factor 2 -- genetics KW - Antioxidant Response Elements KW - NF-E2-Related Factor 2 -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1081875900?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Pharmacological+reviews&rft.atitle=Molecular+basis+of+electrophilic+and+oxidative+defense%3A+promises+and+perils+of+Nrf2.&rft.au=Ma%2C+Qiang%3BHe%2C+Xiaoqing&rft.aulast=Ma&rft.aufirst=Qiang&rft.date=2012-10-01&rft.volume=64&rft.issue=4&rft.spage=1055&rft.isbn=&rft.btitle=&rft.title=Pharmacological+reviews&rft.issn=1521-0081&rft_id=info:doi/10.1124%2Fpr.110.004333 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2013-02-21 N1 - Date created - 2012-10-01 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Proc Natl Acad Sci U S A. 1997 May 13;94(10):5361-6 [9144242] Nucleic Acids Res. 1997 Aug 1;25(15):2953-59 [9224592] Biochem Biophys Res Commun. 1997 Jul 18;236(2):313-22 [9240432] EMBO J. 1998 Mar 16;17(6):1779-87 [9501099] J Biol Chem. 2005 Sep 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2013;53:401-26 [23294312] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1124/pr.110.004333 ER - TY - JOUR T1 - Joint toxicity of alkoxyethanol mixtures: contribution of in silico applications. AN - 1034514077; 22749914 AB - Exposure to chemicals occurs often as mixtures. Presented in this paper is information on alkoxyethanols and the impact they might have on human health in combination with some commonly found aliphatic and aromatic compounds. Our studies to evaluate the joint toxicity of these chemicals among themselves and in combination with other chemicals reveal a variety of possible outcomes depending on the exposure scenario. The interactions are predominantly based on metabolic pathways and are common among several solvents and organic compounds. Quantitative structure activity relationship (QSAR) analysis can be used with high confidence to identify chemicals that will interact to influence overall joint toxicity. Potential human exposure to a combination of alkoxyethanol, toluene and substituted benzenes may increase reproductive and developmental disease conditions. Inheritable gene alterations result in changes in the enzyme function in different subpopulations causing variations in quantity and/or quality of particular isoenzymes. These changes are responsible for differential metabolism of chemicals in species, genders, and life stages and are often the basis of a population's susceptibility. Unique genotypes introduced as a function of migration can alter the genetic makeup of any given population. Hence special consideration should be given to susceptible populations while conducting chemical health risk assessments. Published by Elsevier Inc. JF - Regulatory toxicology and pharmacology : RTP AU - Pohl, H R AU - Ruiz, P AU - Scinicariello, F AU - Mumtaz, M M AD - Agency for Toxic Substances and Disease Registry, US Department of Health and Human Services, Atlanta, GA, USA. hpohl@cdc.gov Y1 - 2012/10// PY - 2012 DA - October 2012 SP - 134 EP - 142 VL - 64 IS - 1 KW - Alcohols KW - 0 KW - Solvents KW - Index Medicus KW - Gene Expression -- drug effects KW - Animals KW - Drug Interactions KW - Quantitative Structure-Activity Relationship KW - Humans KW - Toxicity Tests KW - Species Specificity KW - Male KW - Female KW - Risk Assessment KW - Solvents -- toxicity KW - Solvents -- chemistry KW - Computer Simulation KW - Alcohols -- toxicity KW - Alcohols -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1034514077?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Regulatory+toxicology+and+pharmacology+%3A+RTP&rft.atitle=Joint+toxicity+of+alkoxyethanol+mixtures%3A+contribution+of+in+silico+applications.&rft.au=Pohl%2C+H+R%3BRuiz%2C+P%3BScinicariello%2C+F%3BMumtaz%2C+M+M&rft.aulast=Pohl&rft.aufirst=H&rft.date=2012-10-01&rft.volume=64&rft.issue=1&rft.spage=134&rft.isbn=&rft.btitle=&rft.title=Regulatory+toxicology+and+pharmacology+%3A+RTP&rft.issn=1096-0295&rft_id=info:doi/10.1016%2Fj.yrtph.2012.06.008 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2013-01-08 N1 - Date created - 2012-08-20 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.yrtph.2012.06.008 ER - TY - JOUR T1 - Seasonality, Timing, and Climate Drivers of Influenza Activity Worldwide AN - 1642625647; 20900019 AB - Background. Although influenza is a vaccine-preventable disease that annually causes substantial disease burden, data on virus activity in tropical countries are limited. We analyzed publicly available influenza data to better understand the global circulation of influenza viruses. Method. We reviewed open-source, laboratory-confirmed influenza surveillance data. For each country, we abstracted data on the percentage of samples testing positive for influenza each epidemiologic week from the annual number of samples testing positive for influenza. The start of influenza season was defined as the first week when the proportion of samples that tested positive remained above the annual mean. We assessed the relationship between percentage of samples testing positive and mean monthly temperature with use of regression models. Findings. We identified data on laboratory-confirmed influenza virus infection from 85 countries. More than one influenza epidemic period per year was more common in tropical countries (41%) than in temperate countries (15%). Year-round activity (ie, influenza virus identified each week having [> or =]10 specimens submitted) occurred in 3 (7%) of 43 temperate, 1 (17%) of 6 subtropical, and 11 (37%) of 30 tropical countries with available data (P = .006). Percentage positivity was associated with low temperature (P = .001). Interpretation. Annual influenza epidemics occur in consistent temporal patterns depending on climate. JF - Journal of Infectious Diseases AU - Baumgartner, Eduardo Azziz AU - Dao, Christine N AU - Nasreen, Sharifa AU - Bhuiyan, Mejbah Uddin AU - Mah-E-Muneer, Syeda AU - Al Mamun, Abdullah AU - Sharker, M A Yushuf AU - Zaman, Rashid Uz AU - Cheng, Po-Yung AU - Klimov, Alexander I AU - Widdowson, Marc-Alain AU - Uyeki, Timothy M AU - Luby, Stephen P AU - Mounts, Anthony AU - Bresee, Joseph AD - Centers for Disease Control and Prevention, Influenza Division, Atlanta, Georgia; Influenza Division, MS A32, 1600 Clifton Rd, NE, Atlanta, GA 30333, eha9@cdc.gov Y1 - 2012/09/15/ PY - 2012 DA - 2012 Sep 15 SP - 838 EP - 846 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 206 IS - 6 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Temperature effects KW - Data processing KW - Epidemics KW - Viruses KW - Climate KW - Temperature KW - Infection KW - Models KW - Influenza KW - Influenza virus KW - Low temperature KW - Infectious diseases KW - Reviews KW - Regression analysis KW - Vaccines KW - Seasonal variations KW - V 22300:Methods KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1642625647?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Seasonality%2C+Timing%2C+and+Climate+Drivers+of+Influenza+Activity+Worldwide&rft.au=Baumgartner%2C+Eduardo+Azziz%3BDao%2C+Christine+N%3BNasreen%2C+Sharifa%3BBhuiyan%2C+Mejbah+Uddin%3BMah-E-Muneer%2C+Syeda%3BAl+Mamun%2C+Abdullah%3BSharker%2C+M+A+Yushuf%3BZaman%2C+Rashid+Uz%3BCheng%2C+Po-Yung%3BKlimov%2C+Alexander+I%3BWiddowson%2C+Marc-Alain%3BUyeki%2C+Timothy+M%3BLuby%2C+Stephen+P%3BMounts%2C+Anthony%3BBresee%2C+Joseph&rft.aulast=Baumgartner&rft.aufirst=Eduardo&rft.date=2012-09-15&rft.volume=206&rft.issue=6&rft.spage=838&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjis467 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Temperature effects; Influenza; Epidemics; Data processing; Reviews; Climate; Regression analysis; Infection; Seasonal variations; Models; Low temperature; Infectious diseases; Viruses; Temperature; Vaccines; Influenza virus DO - http://dx.doi.org/10.1093/infdis/jis467 ER - TY - JOUR T1 - Reemergence and Decline of Dengue Virus Serotype 3 in Puerto Rico AN - 1642623750; 20900026 AB - Background. The dengue virus serotype 3 (DENV-3) Indian subcontinent strain emerged in Puerto Rico in 1998 after a 21-year absence. The rapid expansion of DENV-3 on the island correlated with the withdrawal of the other serotypes for 7 years. The DENV-3 prevalence declined in 2008 and remains undetected. Methods. We sequenced complete genomes of 92 DENV-3 clinical isolates to characterize the molecular evolution and phylogeography throughout 10 years of continued sampling (1998-2007). Results. We documented 8 distinct lineages that emerged simultaneously and evolved independently. Two of the 8 lineages were highly associated with transient introductions of foreign viruses, and 2 of the 3 endemic lineages covered the entire study period. We found evidence of temporal-geographical clustering only within the 3 endemic lineages. The phylogeography analysis combined with serotype-specific incidence data showed that transmission of a DENV serotype in a given location and time is usually correlated with the absence of the other serotype. Conclusions. Our study shows the cotransmission of DENV-3 lineages through a complex dissemination pattern dissimilar to the evolutionary dynamics of the other serotypes in the island. High virus genetic diversity and a large naive population were underlying factors in the expansion and collapse of DENV-3 in Puerto Rico. JF - Journal of Infectious Diseases AU - Santiago, Gilberto A AU - McElroy-Horne, Kate AU - Lennon, Niall J AU - Santiago, Luis M AU - Birren, Bruce W AU - Henn, Matthew R AU - Munoz-Jordan, Jorge L AD - Division of Vector-borne Infectious Diseases, Dengue Branch, Centers for Disease Control and Prevention, San Juan, Puerto Rico, jmunoz@cdc.gov Y1 - 2012/09/15/ PY - 2012 DA - 2012 Sep 15 SP - 893 EP - 901 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 206 IS - 6 SN - 0022-1899, 0022-1899 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Dengue virus KW - Clinical isolates KW - Genomes KW - Human diseases KW - Serotypes KW - Data processing KW - molecular evolution KW - Nucleotide sequence KW - Viruses KW - Genetic diversity KW - Public health KW - Population genetics KW - Endemic species KW - Islands KW - Infectious diseases KW - ASW, Caribbean Sea, Greater Antilles, Puerto Rico KW - Dengue KW - Sampling KW - Q1 08443:Population genetics KW - Q5 08524:Public health, medicines, dangerous organisms KW - H 0500:General KW - V 22310:Genetics, Taxonomy & Structure UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1642623750?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Reemergence+and+Decline+of+Dengue+Virus+Serotype+3+in+Puerto+Rico&rft.au=Santiago%2C+Gilberto+A%3BMcElroy-Horne%2C+Kate%3BLennon%2C+Niall+J%3BSantiago%2C+Luis+M%3BBirren%2C+Bruce+W%3BHenn%2C+Matthew+R%3BMunoz-Jordan%2C+Jorge+L&rft.aulast=Santiago&rft.aufirst=Gilberto&rft.date=2012-09-15&rft.volume=206&rft.issue=6&rft.spage=893&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjis426 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Genomes; Population genetics; Human diseases; Endemic species; Infectious diseases; Nucleotide sequence; Viruses; Public health; Clinical isolates; molecular evolution; Data processing; Islands; Serotypes; Genetic diversity; Sampling; Dengue; Dengue virus; ASW, Caribbean Sea, Greater Antilles, Puerto Rico DO - http://dx.doi.org/10.1093/infdis/jis426 ER - TY - JOUR T1 - Multiwalled Carbon Nanotube-Induced Gene Signatures in the Mouse Lung: Potential Predictive Value for Human Lung Cancer Risk and Prognosis AN - 1257777934; 17487726 AB - Concerns over the potential for multiwalled carbon nanotubes (MWCNT) to induce lung carcinogenesis have emerged. This study sought to (1) identify gene expression signatures in the mouse lungs following pharyngeal aspiration of well-dispersed MWCNT and (2) determine if these genes were associated with human lung cancer risk and progression. Genome-wide mRNA expression profiles were analyzed in mouse lungs (n = 160) exposed to 0, 10, 20, 40, or 80 mu g of MWCNT by pharyngeal aspiration at 1, 7, 28, and 56 d postexposure. By using pairwise statistical analysis of microarray (SAM) and linear modeling, 24 genes were selected, which have significant changes in at least two time points, have a more than 1.5-fold change at all doses, and are significant in the linear model for the dose or the interaction of time and dose. Additionally, a 38-gene set was identified as related to cancer from 330 genes differentially expressed at d 56 postexposure in functional pathway analysis. Using the expression profiles of the cancer-related gene set in 8 mice at d 56 postexposure to 10 mu g of MWCNT, a nearest centroid classification accurately predicts human lung cancer survival with a significant hazard ratio in training set (n = 256) and test set (n = 186). Furthermore, both gene signatures were associated with human lung cancer risk (n = 164) with significant odds ratios. These results may lead to development of a surveillance approach for early detection of lung cancer and prognosis associated with MWCNT in the workplace. JF - Journal of Toxicology and Environmental Health, Part A: Current Issues AU - Guo, Nancy L AU - Wan, Ying-Wooi AU - Denvir, James AU - Porter, Dale W AU - Pacurari, Maricica AU - Wolfarth, Michael G AU - Castranova, Vincent AU - Qian, Yong AD - Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, West Virginia, USA, yaq2@cdc.gov Y1 - 2012/09/15/ PY - 2012 DA - 2012 Sep 15 SP - 1129 EP - 1153 PB - Taylor & Francis Group Ltd., 2 Park Square Oxford OX14 4RN United Kingdom VL - 75 IS - 18 SN - 1528-7394, 1528-7394 KW - Genetics Abstracts; Environment Abstracts; Toxicology Abstracts KW - Pharynx KW - Statistical analysis KW - Prognosis KW - Animal models KW - Survival KW - Mice KW - Cancer KW - Nanotechnology KW - Models KW - Gene expression KW - Carbon KW - Classification KW - Carcinogenesis KW - nanotubes KW - Lung cancer KW - X 24360:Metals KW - G 07730:Development & Cell Cycle KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1257777934?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.atitle=Multiwalled+Carbon+Nanotube-Induced+Gene+Signatures+in+the+Mouse+Lung%3A+Potential+Predictive+Value+for+Human+Lung+Cancer+Risk+and+Prognosis&rft.au=Guo%2C+Nancy+L%3BWan%2C+Ying-Wooi%3BDenvir%2C+James%3BPorter%2C+Dale+W%3BPacurari%2C+Maricica%3BWolfarth%2C+Michael+G%3BCastranova%2C+Vincent%3BQian%2C+Yong&rft.aulast=Guo&rft.aufirst=Nancy&rft.date=2012-09-15&rft.volume=75&rft.issue=18&rft.spage=1129&rft.isbn=&rft.btitle=&rft.title=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.issn=15287394&rft_id=info:doi/10.1080%2F15287394.2012.699852 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-12-01 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Gene expression; Pharynx; Carbon; Classification; Carcinogenesis; Animal models; Prognosis; Statistical analysis; nanotubes; Survival; Models; Lung cancer; Mice; Cancer; Nanotechnology DO - http://dx.doi.org/10.1080/15287394.2012.699852 ER - TY - CPAPER T1 - The CDC Reference Laboratory and Serologic Diagnosis T2 - 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AN - 1313125005; 6195476 JF - 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AU - Wilkins, Patricia Y1 - 2012/09/09/ PY - 2012 DA - 2012 Sep 09 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313125005?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=52nd+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.atitle=The+CDC+Reference+Laboratory+and+Serologic+Diagnosis&rft.au=Wilkins%2C+Patricia&rft.aulast=Wilkins&rft.aufirst=Patricia&rft.date=2012-09-09&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=52nd+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.issn=&rft_id=info:doi/ L2 - http://www.icaac.org/images/icaac_2012_finalprogram_web4a.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Salmonellosis: Recent Multistate Outbreak Investigations T2 - 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AN - 1313124086; 6195426 JF - 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AU - Behravesh, Casey Y1 - 2012/09/09/ PY - 2012 DA - 2012 Sep 09 KW - Outbreaks KW - Anadromous species KW - Salmonellosis KW - Salmonidae UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313124086?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=52nd+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.atitle=Salmonellosis%3A+Recent+Multistate+Outbreak+Investigations&rft.au=Behravesh%2C+Casey&rft.aulast=Behravesh&rft.aufirst=Casey&rft.date=2012-09-09&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=52nd+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.issn=&rft_id=info:doi/ L2 - http://www.icaac.org/images/icaac_2012_finalprogram_web4a.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - New Prevalence Survey Tools from the CDC T2 - 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AN - 1313117770; 6185786 JF - 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AU - Magill, Shelley Y1 - 2012/09/09/ PY - 2012 DA - 2012 Sep 09 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313117770?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=52nd+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.atitle=New+Prevalence+Survey+Tools+from+the+CDC&rft.au=Magill%2C+Shelley&rft.aulast=Magill&rft.aufirst=Shelley&rft.date=2012-09-09&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=52nd+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.issn=&rft_id=info:doi/ L2 - http://www.icaac.org/images/icaac_2012_finalprogram_web4a.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Emergence of an Animal-Origin Influenza A H3N2 Virus in the US T2 - 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AN - 1313115738; 6195395 JF - 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AU - Finelli, Lyn Y1 - 2012/09/09/ PY - 2012 DA - 2012 Sep 09 KW - Influenza UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313115738?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=52nd+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.atitle=Emergence+of+an+Animal-Origin+Influenza+A+H3N2+Virus+in+the+US&rft.au=Finelli%2C+Lyn&rft.aulast=Finelli&rft.aufirst=Lyn&rft.date=2012-09-09&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=52nd+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.issn=&rft_id=info:doi/ L2 - http://www.icaac.org/images/icaac_2012_finalprogram_web4a.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - CDC and Public Health Careers in Global Health T2 - 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AN - 1313077577; 6185793 JF - 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AU - Cetron, Martin Y1 - 2012/09/09/ PY - 2012 DA - 2012 Sep 09 KW - Public health KW - Careers UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313077577?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=52nd+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.atitle=CDC+and+Public+Health+Careers+in+Global+Health&rft.au=Cetron%2C+Martin&rft.aulast=Cetron&rft.aufirst=Martin&rft.date=2012-09-09&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=52nd+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.issn=&rft_id=info:doi/ L2 - http://www.icaac.org/images/icaac_2012_finalprogram_web4a.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - CLSI and EUCAST Update T2 - 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AN - 1313075738; 6185721 JF - 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AU - Patel, Jean Y1 - 2012/09/09/ PY - 2012 DA - 2012 Sep 09 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313075738?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=52nd+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.atitle=CLSI+and+EUCAST+Update&rft.au=Patel%2C+Jean&rft.aulast=Patel&rft.aufirst=Jean&rft.date=2012-09-09&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=52nd+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.issn=&rft_id=info:doi/ L2 - http://www.icaac.org/images/icaac_2012_finalprogram_web4a.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Global Measles: What's Next? T2 - 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AN - 1313056994; 6185593 JF - 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AU - Seward, Jane Y1 - 2012/09/09/ PY - 2012 DA - 2012 Sep 09 KW - Measles UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313056994?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=52nd+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.atitle=Global+Measles%3A+What%27s+Next%3F&rft.au=Seward%2C+Jane&rft.aulast=Seward&rft.aufirst=Jane&rft.date=2012-09-09&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=52nd+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.issn=&rft_id=info:doi/ L2 - http://www.icaac.org/images/icaac_2012_finalprogram_web4a.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - JOUR T1 - BARTONELLA SPECIES IN DOGS AND THEIR ECTOPARASITES FROM KHON KAEN PROVINCE, THAILAND AN - 1171899875; 17343996 AB - In order to access the prevalence of Bartonella species in dogs, whole blood and any associated ectoparasites were collected from 164 dogs with owners in 25 villages throughout Khon Kaen Province. DNA was extracted from dog blood, 92 ticks (Rhipicephalus sanguineus) and 137 fleas (Ctenocephalides spp) and screened by PCR using intergenic spacer region and citrate synthase gene primers. B. clarridgeiae DNA was detected in blood of 3 dogs, 4 C. felis and 1 C. canis; B. rochalimae DNA was found in 1 tick; and B. vinsonii subsp vinsonii DNA was found in 2 C. felis. The findings indicate that dogs residing in northeast Thailand are exposed to diverse Bartonella species that are also potential human pathogens. JF - Southeast Asian Journal of Tropical Medicine & Public Health AU - Billeter, SA AU - Sangmaneedet, S AU - Kosakewich, R C AU - Kosoy, MY AD - Division of Vector Borne Diseases, Centers for Disease Control and Prevention, 3150 Rampart Road, Fort Collins, Colorado 80521, United States, mck3@cdc.gov Y1 - 2012/09// PY - 2012 DA - Sep 2012 SP - 1186 EP - 1192 VL - 43 IS - 5 SN - 0125-1562, 0125-1562 KW - Entomology Abstracts; Microbiology Abstracts B: Bacteriology KW - Blood KW - Citric acid KW - Pathogens KW - Polymerase chain reaction KW - Primers KW - Public health KW - Spacer region KW - ectoparasites KW - Canis KW - Felis KW - Bartonella KW - Ixodidae KW - Ctenocephalides KW - Rhipicephalus sanguineus KW - J 02410:Animal Diseases KW - Z 05350:Medical, Veterinary, and Agricultural Entomology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1171899875?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Southeast+Asian+Journal+of+Tropical+Medicine+%26+Public+Health&rft.atitle=BARTONELLA+SPECIES+IN+DOGS+AND+THEIR+ECTOPARASITES+FROM+KHON+KAEN+PROVINCE%2C+THAILAND&rft.au=Billeter%2C+SA%3BSangmaneedet%2C+S%3BKosakewich%2C+R+C%3BKosoy%2C+MY&rft.aulast=Billeter&rft.aufirst=SA&rft.date=2012-09-01&rft.volume=43&rft.issue=5&rft.spage=1186&rft.isbn=&rft.btitle=&rft.title=Southeast+Asian+Journal+of+Tropical+Medicine+%26+Public+Health&rft.issn=01251562&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-11-01 N1 - Last updated - 2012-12-14 N1 - SubjectsTermNotLitGenreText - Blood; Spacer region; Polymerase chain reaction; Primers; Pathogens; ectoparasites; Citric acid; Public health; Canis; Felis; Ixodidae; Bartonella; Rhipicephalus sanguineus; Ctenocephalides ER - TY - JOUR T1 - A Proposed Theory on Biodynamic Frequency Weighting for Hand-Transmitted Vibration Exposure AN - 1171892730; 17349865 AB - The objective of this study is to propose a theory on the biodynamic frequency weighting for studying hand-transmitted vibration exposures and vibration-induced effects. We hypothesize that the development of a vibration effect is the result of two consecutive but synergistic processes: biodynamic responses to input vibration and biological responses to the biomechanical stimuli resulting from the biodynamic responses. Hence, we further hypothesize that the frequency-dependency (W) of the effect generally includes two components: a biodynamic frequency weighting (W1) and a biological frequency weighting (W2), or W=W1 times W2. These hypotheses are consistent with the stress and strain analysis theory and methods widely used in structural dynamics and biomechanics. The factorization may make it easier to study the complex frequency-dependency using different approaches: the biodynamic frequency weighting depends on the passive physical response of the system to vibration, and it can thus be determined by examining the biodynamic response of the system using various engineering methods; on the other hand, the biological frequency weighting depends on the biological mechanisms of the effects, and it can be investigated by studying the psychophysical, physiological, and pathological responses. To help test these hypotheses, this study reviewed and further developed methods to derive the finger biodynamic frequency weighting. As a result, preliminary finger biodynamic frequency weightings are proposed. The implications of the proposed theory and the preliminary biodynamic frequency weightings are also discussed. JF - Industrial Health AU - Dong, R G AU - Welcome, DE AU - Mcdowell, T W AU - Xu, X S AU - Krajnak, K AU - Wu, J Z AD - Engineering and Control Technology Branch, National Institute for Occupational Safety and Health, USA, rkd6@cdc.gov Y1 - 2012/09// PY - 2012 DA - Sep 2012 SP - 412 EP - 424 VL - 50 IS - 5 SN - 0019-8366, 0019-8366 KW - Toxicology Abstracts; Health & Safety Science Abstracts KW - Vibrations KW - Vibration KW - Reviews KW - biomechanics KW - Physiology KW - Stress KW - Psychophysics KW - Biomechanics KW - Finger KW - H 1000:Occupational Safety and Health KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1171892730?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Industrial+Health&rft.atitle=A+Proposed+Theory+on+Biodynamic+Frequency+Weighting+for+Hand-Transmitted+Vibration+Exposure&rft.au=Dong%2C+R+G%3BWelcome%2C+DE%3BMcdowell%2C+T+W%3BXu%2C+X+S%3BKrajnak%2C+K%3BWu%2C+J+Z&rft.aulast=Dong&rft.aufirst=R&rft.date=2012-09-01&rft.volume=50&rft.issue=5&rft.spage=412&rft.isbn=&rft.btitle=&rft.title=Industrial+Health&rft.issn=00198366&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-11-01 N1 - Last updated - 2013-06-28 N1 - SubjectsTermNotLitGenreText - Vibrations; Reviews; Stress; Psychophysics; Biomechanics; Finger; Vibration; Physiology; biomechanics ER - TY - JOUR T1 - Prevalence and Diversity of Bartonella spp. in Bats in Peru AN - 1125227047; 17254213 AB - Bartonella infections were investigated in bats in the Amazon part of Peru. A total of 112 bats belonging to 19 species were surveyed. Bartonella bacteria were cultured from 24.1% of the bats (27/112). Infection rates ranged from 0% to 100% per bat species. Phylogenetic analyses of gltA of the Bartonella isolates revealed 21 genetic variants clustering into 13 divergent phylogroups. Some Bartonella strains were shared by bats of multiple species, and bats of some species were infected with multiple Bartonella strains, showing no evident specific Bartonella sp.-bat relationships. Rarely found in other bat species, the Bartonella strains of phylogroups I and III discovered from the common vampire bats (Desmodus rotundus) were more specific to the host bat species, suggesting some level of host specificity. JF - American Journal of Tropical Medicine and Hygiene AU - Bai, Y AU - Recuenco, S AU - Gilbert, A T AU - Osikowicz, L M AU - Gomez, J AU - Rupprecht, C AU - Kosoy, MY AD - Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, 3150 Rampart Road, Fort Collins, CO 80521, USA, YBail@cdc.gov Y1 - 2012/09// PY - 2012 DA - September 2012 SP - 518 EP - 523 VL - 87 IS - 3 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology KW - Phylogeny KW - Host specificity KW - Bartonella KW - Desmodus rotundus KW - Infection KW - J 02310:Genetics & Taxonomy KW - K 03310:Genetics & Taxonomy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1125227047?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Prevalence+and+Diversity+of+Bartonella+spp.+in+Bats+in+Peru&rft.au=Bai%2C+Y%3BRecuenco%2C+S%3BGilbert%2C+A+T%3BOsikowicz%2C+L+M%3BGomez%2C+J%3BRupprecht%2C+C%3BKosoy%2C+MY&rft.aulast=Bai&rft.aufirst=Y&rft.date=2012-09-01&rft.volume=87&rft.issue=3&rft.spage=518&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.2012.12-0097 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-10-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Phylogeny; Host specificity; Infection; Bartonella; Desmodus rotundus DO - http://dx.doi.org/10.4269/ajtmh.2012.12-0097 ER - TY - JOUR T1 - Incidence and Cost of Depression After Occupational Injury AN - 1113213013; 17216871 AB - Objectives: We examined if injured workers were more likely than nonin-jured workers to be treated for depression after an occupational injury and estimated the cost paid by group medical insurance. Method: Nearly 367,900 injured and noninjured workers were drawn from the 2005 Thomson Reuters MarketScan data. Descriptive, logistic, and two-part model regression analyses were used. Results: The odds of injured workers being treated for depression within the study period were 45% higher than those of noninjured workers (95% confidence interval, 1.17-1.78). The unconditional average cost of outpatient depression treatment was 63% higher for injured workers than for noninjured workers. Conclusions: Injured workers were more likely than noninjured workers to suffer from depression during the study period. Consequently, additional costs are incurred for treating injured workers' depression; these costs were not covered by the workers' compensation system. JF - Journal of Occupational and Environmental Medicine AU - Asfaw, A AU - Souza, K AD - Centers for Disease Control and Prevention--National Institute for Occupational Safety and Health, 395 E Street, SW, Washington, DC 20201, USA, hqp0@cdc.gov Y1 - 2012/09// PY - 2012 DA - Sep 2012 SP - 1086 EP - 1091 VL - 54 IS - 9 SN - 1076-2752, 1076-2752 KW - Health & Safety Science Abstracts KW - workers' compensation KW - Depression KW - Occupational safety KW - Insurance KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1113213013?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Incidence+and+Cost+of+Depression+After+Occupational+Injury&rft.au=Asfaw%2C+A%3BSouza%2C+K&rft.aulast=Asfaw&rft.aufirst=A&rft.date=2012-09-01&rft.volume=54&rft.issue=9&rft.spage=1086&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e3182636e29 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-10-01 N1 - Last updated - 2013-07-26 N1 - SubjectsTermNotLitGenreText - workers' compensation; Depression; Occupational safety; Insurance DO - http://dx.doi.org/10.1097/JOM.0b013e3182636e29 ER - TY - JOUR T1 - Efficacy of Indoor Residual Spraying Using Lambda-Cyhalothrin for Controlling Nontarget Vector Fleas (Siphonaptera) on Commensal Rats in a Plague Endemic Region of Northwestern Uganda AN - 1093470631; 17188374 AB - Over the past two decades, the majority of human plague cases have been reported from areas in Africa, including Uganda. In an effort to develop affordable plague control methods within an integrated vector control framework, we evaluated the efficacy of indoor residual spraying (IRS) techniques commonly used for mosquito control for controlling fleas on hut-dwelling commensal rodents in a plague-endemic region of Uganda. We evaluated both the standard IRS spraying (walls and ceiling) and a modified IRS technique that included insecticide application on not only on walls and ceiling but also a portion of the floor of each treated hut. Our study demonstrated that both the standard and modified IRS applications were effective at significantly reducing the flea burden and flea infestation of commensal rodents for up to 100 d after application, suggesting that IRS could potentially provide simultaneous control of mosquito and fleaborne diseases. JF - Journal of Medical Entomology AU - Borchert, Jeff N AU - Eisen, Rebecca J AU - Atiku, Linda A AU - Delorey, Mark J AU - Mpanga, Joseph T AU - Babi, Nackson AU - Enscore, Russell E AU - Gage, Kenneth L AD - Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, 3150 Rampait Rd., Fort Collins, CO 80522., gqxl@cdc.gov Y1 - 2012/09// PY - 2012 DA - Sep 2012 SP - 1027 EP - 1034 PB - Entomological Society of America, 9301 Annapolis Rd. Lanham MD 20706 United States VL - 49 IS - 5 SN - 0022-2585, 0022-2585 KW - ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Entomology Abstracts KW - indoor residual spray KW - Rattus rattus KW - plague KW - flea KW - lambda-cyhalothrin KW - Commensals KW - Disease control KW - Vectors KW - Uganda KW - Pest control KW - Hosts KW - Spraying KW - Disease transmission KW - Endemic species KW - Infestation KW - Insecticides KW - Siphonaptera KW - Africa KW - Plague KW - Aquatic insects KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - Q1 08485:Species interactions: pests and control KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1093470631?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Medical+Entomology&rft.atitle=Efficacy+of+Indoor+Residual+Spraying+Using+Lambda-Cyhalothrin+for+Controlling+Nontarget+Vector+Fleas+%28Siphonaptera%29+on+Commensal+Rats+in+a+Plague+Endemic+Region+of+Northwestern+Uganda&rft.au=Borchert%2C+Jeff+N%3BEisen%2C+Rebecca+J%3BAtiku%2C+Linda+A%3BDelorey%2C+Mark+J%3BMpanga%2C+Joseph+T%3BBabi%2C+Nackson%3BEnscore%2C+Russell+E%3BGage%2C+Kenneth+L&rft.aulast=Borchert&rft.aufirst=Jeff&rft.date=2012-09-01&rft.volume=49&rft.issue=5&rft.spage=1027&rft.isbn=&rft.btitle=&rft.title=Journal+of+Medical+Entomology&rft.issn=00222585&rft_id=info:doi/10.1603%2FME11230 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-10-01 N1 - Number of references - 53 N1 - Last updated - 2014-12-11 N1 - SubjectsTermNotLitGenreText - Infestation; Endemic species; Insecticides; Disease control; Commensals; Pest control; Hosts; Aquatic insects; Disease transmission; Vectors; Plague; Spraying; Siphonaptera; Africa; Uganda DO - http://dx.doi.org/10.1603/ME11230 ER - TY - JOUR T1 - Respiratory and olfactory cytotoxicity of inhaled 2,3-pentanedione in Sprague-Dawley rats. AN - 1034514901; 22894831 AB - Flavorings-related lung disease is a potentially disabling disease of food industry workers associated with exposure to the α-diketone butter flavoring, diacetyl (2,3-butanedione). To investigate the hypothesis that another α-diketone flavoring, 2,3-pentanedione, would cause airway damage, rats that inhaled air, 2,3-pentanedione (112, 241, 318, or 354 ppm), or diacetyl (240 ppm) for 6 hours were sacrificed the following day. Rats inhaling 2,3-pentanedione developed necrotizing rhinitis, tracheitis, and bronchitis comparable to diacetyl-induced injury. To investigate delayed toxicity, additional rats inhaled 318 (range, 317.9-318.9) ppm 2,3-pentanedione for 6 hours and were sacrificed 0 to 2, 12 to 14, or 18 to 20 hours after exposure. Respiratory epithelial injury in the upper nose involved both apoptosis and necrosis, which progressed through 12 to 14 hours after exposure. Olfactory neuroepithelial injury included loss of olfactory neurons that showed reduced expression of the 2,3-pentanedione-metabolizing enzyme, dicarbonyl/L-xylulose reductase, relative to sustentacular cells. Caspase 3 activation occasionally involved olfactory nerve bundles that synapse in the olfactory bulb (OB). An additional group of rats inhaling 270 ppm 2,3-pentanedione for 6 hours 41 minutes showed increased expression of IL-6 and nitric oxide synthase-2 and decreased expression of vascular endothelial growth factor A in the OB, striatum, hippocampus, and cerebellum using real-time PCR. Claudin-1 expression increased in the OB and striatum. We conclude that 2,3-pentanedione is a respiratory hazard that can also alter gene expression in the brain. Published by Elsevier Inc. JF - The American journal of pathology AU - Hubbs, Ann F AU - Cumpston, Amy M AU - Goldsmith, W Travis AU - Battelli, Lori A AU - Kashon, Michael L AU - Jackson, Mark C AU - Frazer, David G AU - Fedan, Jeffrey S AU - Goravanahally, Madhusudan P AU - Castranova, Vincent AU - Kreiss, Kathleen AU - Willard, Patsy A AU - Friend, Sherri AU - Schwegler-Berry, Diane AU - Fluharty, Kara L AU - Sriram, Krishnan AD - Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA. ahubbs@cdc.gov Y1 - 2012/09// PY - 2012 DA - September 2012 SP - 829 EP - 844 VL - 181 IS - 3 KW - Cadherins KW - 0 KW - Olfactory Marker Protein KW - Pentanones KW - RNA, Messenger KW - Sugar Alcohol Dehydrogenases KW - EC 1.1.- KW - L-xylulose reductase KW - EC 1.1.1.10 KW - Caspase 3 KW - EC 3.4.22.- KW - Diacetyl KW - K324J5K4HM KW - 2,3-pentanedione KW - K4WBE45SCM KW - Abridged Index Medicus KW - Index Medicus KW - Animals KW - Cadherins -- metabolism KW - Reproducibility of Results KW - Neurons -- drug effects KW - Diacetyl -- toxicity KW - Sugar Alcohol Dehydrogenases -- metabolism KW - RNA, Messenger -- genetics KW - Cell Death -- drug effects KW - Epithelium -- drug effects KW - Neurons -- pathology KW - Rats KW - Rats, Sprague-Dawley KW - RNA, Messenger -- metabolism KW - Olfactory Marker Protein -- metabolism KW - Gene Expression Regulation -- drug effects KW - Administration, Inhalation KW - Epithelium -- pathology KW - Time Factors KW - Staining and Labeling KW - Fluorescent Antibody Technique KW - Male KW - Caspase 3 -- metabolism KW - Olfactory Bulb -- pathology KW - Olfactory Bulb -- drug effects KW - Respiratory System -- pathology KW - Pentanones -- toxicity KW - Pentanones -- administration & dosage UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1034514901?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+American+journal+of+pathology&rft.atitle=Respiratory+and+olfactory+cytotoxicity+of+inhaled+2%2C3-pentanedione+in+Sprague-Dawley+rats.&rft.au=Hubbs%2C+Ann+F%3BCumpston%2C+Amy+M%3BGoldsmith%2C+W+Travis%3BBattelli%2C+Lori+A%3BKashon%2C+Michael+L%3BJackson%2C+Mark+C%3BFrazer%2C+David+G%3BFedan%2C+Jeffrey+S%3BGoravanahally%2C+Madhusudan+P%3BCastranova%2C+Vincent%3BKreiss%2C+Kathleen%3BWillard%2C+Patsy+A%3BFriend%2C+Sherri%3BSchwegler-Berry%2C+Diane%3BFluharty%2C+Kara+L%3BSriram%2C+Krishnan&rft.aulast=Hubbs&rft.aufirst=Ann&rft.date=2012-09-01&rft.volume=181&rft.issue=3&rft.spage=829&rft.isbn=&rft.btitle=&rft.title=The+American+journal+of+pathology&rft.issn=1525-2191&rft_id=info:doi/10.1016%2Fj.ajpath.2012.05.021 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-11-08 N1 - Date created - 2012-08-20 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.ajpath.2012.05.021 ER - TY - JOUR T1 - The use of biomarkers in occupational health research, practice, and policy. AN - 1030079056; 21477643 AB - Biomarkers are potentially useful tools for occupational health and safety research, practice, and policy. However, the full realization of this potential has not been achieved. In this paper, the progress made in these three usage areas is reviewed to identify what efforts can be taken to realize the full promise of biomarkers. Biomarker uses are described by a diverse taxonomy that builds on the categories of exposure, effect and susceptibility, and the continuum between exposure and disease prognosis. The most significant uses of biomarkers in occupational health have been in biological monitoring of workers. Other important uses have been in enhancing research and assessing mechanisms of action of occupational toxicants at low exposures. Seven critical areas will influence the extent to which the potential of biomarkers in occupational health and safety is realized. These include: (1) adequate investment in validation; (2) obtaining international agreement on exposure guidelines; (3) exploring the utility of biomarkers in regulation; (4) applying biomarkers to critical occupational safety and health questions; (5) developing the exposome; (6) utilizing biomarkers to address emerging occupational health issues; and (7) continuing to address the ethical and social justice issues related to biomarkers. Overall, if biomarkers are to make a major contribution to occupational health and safety then a more holistic approach to bringing them from the laboratory to practice will be needed. Published by Elsevier Ireland Ltd. JF - Toxicology letters AU - Schulte, P A AU - Hauser, J E AD - National Institute for Occupational Safety and Health, 4676 Columbia Parkway, Cincinnati, OH 45226, USA. PSchulte@cdc.gov Y1 - 2012/08/13/ PY - 2012 DA - 2012 Aug 13 SP - 91 EP - 99 VL - 213 IS - 1 KW - Biomarkers KW - 0 KW - Index Medicus KW - Occupational Diseases -- diagnosis KW - Occupational Health KW - Humans KW - Occupational Diseases -- chemically induced KW - Biomarkers -- analysis KW - Health Policy KW - Occupational Exposure -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1030079056?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+letters&rft.atitle=The+use+of+biomarkers+in+occupational+health+research%2C+practice%2C+and+policy.&rft.au=Schulte%2C+P+A%3BHauser%2C+J+E&rft.aulast=Schulte&rft.aufirst=P&rft.date=2012-08-13&rft.volume=213&rft.issue=1&rft.spage=91&rft.isbn=&rft.btitle=&rft.title=Toxicology+letters&rft.issn=1879-3169&rft_id=info:doi/10.1016%2Fj.toxlet.2011.03.027 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-10-10 N1 - Date created - 2012-07-27 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.toxlet.2011.03.027 ER - TY - JOUR T1 - Lead in drinking water and human blood lead levels in the United States. AN - 1033154247; 22874873 AB - Lead is a pervasive environmental contaminant. The adverse health effects of lead exposure in children and adults are well documented, and no safe blood lead threshold in children has been identified. Lead can be ingested from various sources, including lead paint and house dust contaminated by lead paint, as well as soil, drinking water, and food. The concentration of lead, total amount of lead consumed, and duration of lead exposure influence the severity of health effects. Because lead accumulates in the body, all sources of lead should be controlled or eliminated to prevent childhood lead poisoning. Beginning in the 1970s, lead concentrations in air, tap water, food, dust, and soil began to be substantially reduced, resulting in significantly reduced blood lead levels (BLLs) in children throughout the United States. However, children are still being exposed to lead, and many of these children live in housing built before the 1978 ban on lead-based residential paint. These homes might contain lead paint hazards, as well as drinking water service lines made from lead, lead solder, or plumbing materials that contain lead. Adequate corrosion control reduces the leaching of lead plumbing components or solder into drinking water. The majority of public water utilities are in compliance with the Safe Drinking Water Act Lead and Copper Rule (LCR) of 1991. However, some children are still exposed to lead in drinking water. EPA is reviewing LCR, and additional changes to the rule are expected that will further protect public health. Childhood lead poisoning prevention programs should be made aware of the results of local public water system lead monitoring measurement under LCR and consider drinking water as a potential cause of increased BLLs, especially when other sources of lead exposure are not identified. JF - MMWR supplements AU - Brown, Mary Jean AU - Margolis, Stephen AD - Division of Emergency and Environmental Health Services, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Atlanta, GA 30084, USA. mjb5@cdc.gov Y1 - 2012/08/10/ PY - 2012 DA - 2012 Aug 10 SP - 1 EP - 9 VL - 61 IS - 4 KW - Lead KW - 2P299V784P KW - Index Medicus KW - United States Environmental Protection Agency KW - History, 20th Century KW - History, 21st Century KW - Guideline Adherence KW - Humans KW - Safety KW - History, 18th Century KW - History, 19th Century KW - Child KW - Child, Preschool KW - Environmental Monitoring KW - Infant KW - Mass Screening KW - Public Health KW - Adult KW - Epidemiological Monitoring KW - United States -- epidemiology KW - Lead Poisoning -- prevention & control KW - Water Supply -- standards KW - Water Supply -- history KW - Lead -- toxicity KW - Environmental Exposure KW - Lead Poisoning -- epidemiology KW - Lead -- analysis KW - Lead -- blood UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1033154247?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=MMWR+supplements&rft.atitle=Lead+in+drinking+water+and+human+blood+lead+levels+in+the+United+States.&rft.au=Brown%2C+Mary+Jean%3BMargolis%2C+Stephen&rft.aulast=Brown&rft.aufirst=Mary&rft.date=2012-08-10&rft.volume=61&rft.issue=4&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=MMWR+supplements&rft.issn=2380-8942&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-10-25 N1 - Date created - 2012-08-09 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Timing of hepatitis B vaccination and impact of non-simultaneous vaccination with DTP vaccine following introduction of a hepatitis B birth dose in the Philippines AN - 1728652953; 2011-328314 AB - Timely administration of hepatitis B vaccine beginning at birth prevents up to 95 per cent of perinatally acquired hepatitis B virus infections in infants of infected mothers. The Philippines changed its national HepB schedule in 2007 to include a dose at birth. We evaluated vaccination schedule change by reviewing infant records at selected health facilities to measure completeness and timeliness of HepB administration and frequency of recommended, simultaneous vaccination with diphtheria-tetanus-pertussis (DTP) vaccine. Of 1431 sampled infants, 1106 (77 per cent) completed the HepB series and 10 per cent followed the national schedule. The proportion with timely vaccination declined with successive doses: HepB1 (71 per cent), HepB2 (47 per cent), and HepB3 (26 per cent). Twenty-six per cent received HepB2 simultaneously with DTP1 and 34 per cent received HepB3 simultaneously with DTP3. If HepB and DTP vaccination were given simultaneously, 10 per cent more infants could have received all HepB doses. Program implementers should monitor vaccination timeliness and increase simultaneous administration to improve vaccination coverage and decrease disease incidence. Adapted from the source document. JF - Journal of Public Health Policy AU - Wallace, Aaron S AU - Sobel, Howard AU - Ryman, Tove K AU - Mantaring, Jacinto Blas, III AU - Silvestre, Mianne AU - Thorley, Margaret AU - Ducusin, Joyce AU - Nyunt-U, Soe AD - Global Immunization Division, US Centers for Disease Control & Prevention, 1600 Clifton Road, MS-A05, Atlanta, Georgia 30333, USA awallace@cdc.gov Y1 - 2012/08// PY - 2012 DA - August 2012 SP - 368 EP - 381 PB - Palgrave Macmillan, Basingstoke UK VL - 33 IS - 3 SN - 0197-5897, 0197-5897 KW - hepatitis B birth dose, vaccination timeliness, immunization schedule adherence, expanded program on immunization KW - Hepatitis KW - Philippines KW - Mothers KW - Reproductive health KW - Diseases KW - Births KW - Infants KW - Vaccination and vaccines KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1728652953?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Public+Health+Policy&rft.atitle=Timing+of+hepatitis+B+vaccination+and+impact+of+non-simultaneous+vaccination+with+DTP+vaccine+following+introduction+of+a+hepatitis+B+birth+dose+in+the+Philippines&rft.au=Wallace%2C+Aaron+S%3BSobel%2C+Howard%3BRyman%2C+Tove+K%3BMantaring%2C+Jacinto+Blas%2C+III%3BSilvestre%2C+Mianne%3BThorley%2C+Margaret%3BDucusin%2C+Joyce%3BNyunt-U%2C+Soe&rft.aulast=Wallace&rft.aufirst=Aaron&rft.date=2012-08-01&rft.volume=33&rft.issue=3&rft.spage=368&rft.isbn=&rft.btitle=&rft.title=Journal+of+Public+Health+Policy&rft.issn=01975897&rft_id=info:doi/10.1057%2Fjphp.2012.18 LA - English DB - PAIS Index N1 - Date revised - 2015-11-01 N1 - Last updated - 2016-09-28 N1 - CODEN - JPPODK N1 - SubjectsTermNotLitGenreText - Vaccination and vaccines; Hepatitis; Infants; Births; Reproductive health; Philippines; Diseases; Mothers DO - http://dx.doi.org/10.1057/jphp.2012.18 ER - TY - JOUR T1 - Recent trends in the epidemiology of non-typhoidal Salmonella in Israel, 1999-2009 AN - 1367488254; 18059188 AB - The aim of the present study was to assess the recent trends in the epidemiology of non-typhoid Salmonella in Israel using a sentinel laboratory-based surveillance network. Between 1999 and 2009, 8758 Salmonella stool isolates were reported by five sentinel laboratories. There was a significant decrease in the incidence rate of Salmonella isolates from 70.5/100 000 in 1999 to 21.6/100 000 in 2005 followed by a slight increase to 30.3/100 000 in 2009. Of all Salmonella, 64.3% were isolated from children in the 0-4 years age group. Up to 2008, S. Enteritidis was the most prevalent serotype and in 2009 S. Infantis emerged as the most common Salmonella serotype. The decrease in the incidence of S. Enteritidis and S. Typhimurium and increase in S. Infantis among humans were associated with a similar trend among breeding flocks, which followed significant preventive interventions conducted against S. Enteritidis and S. Typhimurium infections in poultry. Tight surveillance and education of food handlers and consumers should be enhanced to reduce the foodborne transmission of Salmonella in Israel. JF - Epidemiology and Infection AU - Bassal, R AU - Reisfeld, A AU - Andorn, N AU - Yishai, R AU - Nissan, I AU - Agmon, V AU - Peled, N AU - Block, C AU - Keller, N AU - KENES, Y AU - Taran, D AU - SCHEMBERG, B AU - Ken-Dror, S AU - ROUACH, T AU - Citron, B AU - Berman, E AU - Green AU - Shohat, T AU - Cohen, D AD - Israel Center for Disease Control, Ministry of Health, Tel Hashomer, Israel; , dancohen@post.tau.ac.il Y1 - 2012/08// PY - 2012 DA - Aug 2012 SP - 1446 EP - 1453 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 140 IS - 8 SN - 0950-2688, 0950-2688 KW - Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts KW - Age KW - Serotypes KW - Israel KW - Salmonella typhimurium KW - Infection KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1367488254?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Recent+trends+in+the+epidemiology+of+non-typhoidal+Salmonella+in+Israel%2C+1999-2009&rft.au=Bassal%2C+R%3BReisfeld%2C+A%3BAndorn%2C+N%3BYishai%2C+R%3BNissan%2C+I%3BAgmon%2C+V%3BPeled%2C+N%3BBlock%2C+C%3BKeller%2C+N%3BKENES%2C+Y%3BTaran%2C+D%3BSCHEMBERG%2C+B%3BKen-Dror%2C+S%3BROUACH%2C+T%3BCitron%2C+B%3BBerman%2C+E%3BGreen%3BShohat%2C+T%3BCohen%2C+D&rft.aulast=Bassal&rft.aufirst=R&rft.date=2012-08-01&rft.volume=140&rft.issue=8&rft.spage=1446&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS095026881100197X LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-06-01 N1 - Number of references - 1 N1 - Last updated - 2014-03-10 N1 - SubjectsTermNotLitGenreText - Serotypes; Infection; Salmonella typhimurium; Israel DO - http://dx.doi.org/10.1017/S095026881100197X ER - TY - JOUR T1 - Design Optimization of a Portable Thermophoretic Precipitator Nanoparticle Sampler AN - 1323256864; 17797028 AB - Researchers at the National Institute for Occupational Safety and Health (NIOSH) are developing methods for characterizing diesel particulate matter in mines. Introduction of novel engine and exhaust aftertreatment technologies in underground mines is changing the nature of diesel emissions, and metrics alternative to the traditional mass-based measurements are being investigated with respect to their ability to capture changes in the properties of diesel aerosols. The emphasis is given to metrics based on measurement of number and surface area concentrations, but analysis of collected particles using electron microscopy (EM) is also employed for detailed particle characterization. To collect samples for EM analysis at remote workplaces, including mining and manufacturing facilities, NIOSH is developing portable particle samplers capable of collecting airborne nano-scale particles. This paper describes the design, construction, and testing of a prototype thermophoretic precipitator (TP) particle sampler optimized for collection of particles in the size range of 1-300 nm. The device comprises heated and cooled metal plates separated by a 0.8 mm channel through which aerosol is drawn by a pump. It weighs about 2 kg, has a total footprint of 27 22 cm, and the collection plate size is approximately 4 8 cm. Low power consumption and enhanced portability were achieved by using moderate flow rates (50-150 cm super(3)/min) and temperature gradients (10-50 K/mm with Delta T between 8 K and 40 K). The collection efficiency of the prototype, measured with a condensation particle counter using laboratory-generated polydisperse submicrometer NaCl aerosols, ranged from 14-99%, depending on temperature gradient and flow rate. Analysis of transmission electron microscopy images of samples collected with the TP confirmed that the size distributions of collected particles determined using EM are in good agreement with those determined using a Fast Mobility Particle Sizer. Copyright 2012 American Association for Aerosol Research JF - Aerosol Science & Technology AU - Miller, Art AU - Marinos, Alek AU - Wendel, Chris AU - King, Grant AU - Bugarski, Aleksandar AD - National Institute for Occupational Safety and Health, Spokane, Washington, USA, ALMiller@cdc.gov Y1 - 2012/08/01/ PY - 2012 DA - 2012 Aug 01 SP - 897 EP - 904 PB - Taylor & Francis Group Ltd., 2 Park Square Oxford OX14 4RN United Kingdom VL - 46 IS - 8 SN - 0278-6826, 0278-6826 KW - Pollution Abstracts; Health & Safety Science Abstracts; Meteorological & Geoastrophysical Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources KW - Aerosols KW - Particle counters KW - Prototypes KW - Occupational safety KW - Temperature KW - Particulates KW - Suspended particulate matter KW - Mines KW - Temperature gradients KW - Nanoparticles KW - Flow rates KW - Power consumption KW - Atmospheric pollution by diesel engines KW - Aerosol research KW - Microscopy KW - Health and safety KW - Condensation KW - Electron microscopy KW - Size distribution KW - Technology KW - M2 551.510.42:Air Pollution (551.510.42) KW - Q2 09188:Atmospheric chemistry KW - P 0000:AIR POLLUTION KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1323256864?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aerosol+Science+%26+Technology&rft.atitle=Design+Optimization+of+a+Portable+Thermophoretic+Precipitator+Nanoparticle+Sampler&rft.au=Miller%2C+Art%3BMarinos%2C+Alek%3BWendel%2C+Chris%3BKing%2C+Grant%3BBugarski%2C+Aleksandar&rft.aulast=Miller&rft.aufirst=Art&rft.date=2012-08-01&rft.volume=46&rft.issue=8&rft.spage=897&rft.isbn=&rft.btitle=&rft.title=Aerosol+Science+%26+Technology&rft.issn=02786826&rft_id=info:doi/10.1080%2F02786826.2012.680551 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-04-01 N1 - Last updated - 2016-02-29 N1 - SubjectsTermNotLitGenreText - Aerosols; Particle counters; Prototypes; Health and safety; Suspended particulate matter; Temperature gradients; Size distribution; Power consumption; Atmospheric pollution by diesel engines; Aerosol research; Condensation; Nanoparticles; Electron microscopy; Occupational safety; Microscopy; Temperature; Particulates; Mines; Flow rates; Technology DO - http://dx.doi.org/10.1080/02786826.2012.680551 ER - TY - JOUR T1 - Identification of Diverse Bartonella Genotypes among Small Mammals from Democratic Republic of Congo and Tanzania AN - 1113223499; 17254183 AB - Small mammals from the Democratic Republic (DR) of the Congo and Tanzania were tested to determine the prevalence and genetic diversity of Bartonella species. The presence of Bartonella DNA was assessed in spleen samples of the animals by rpoB- and gltA-polymerase chain reactions (PCRs). By rpoB-PCR, Bartonella was detected in 8 of 59 animals of DR Congo and in 16 of 39 Tanzanian animals. By gltA-PCR, Bartonella was detected in 5 and 15 animals of DR Congo and Tanzania, respectively. The gene sequences from Arvicanthis neumanni were closely related to Bartonella elizabethae. The genotypes from Lophuromys spp. and from Praomys delectorum were close to Bartonella tribocorum. Five genogroups were not genetically related to any known Bartonella species. These results suggest the need to conduct further studies to establish the zoonotic risks linked with those Bartonella species and, in particular, to verify whether these agents might be responsible for human cases of febrile illness of unknown etiology in Africa. JF - American Journal of Tropical Medicine and Hygiene AU - Gundi, VAKB AU - Kosoy, MY AU - Makundi, R H AU - Laudisoit, A AD - Bartonella Laboratory, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, 3150 Rampart Road, Foothills Research Campus, Fort Collins, CO 80521, USA, mck3@cdc.gov Y1 - 2012/08// PY - 2012 DA - August 2012 SP - 319 EP - 326 VL - 87 IS - 2 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Risk Abstracts KW - Etiology KW - Tanzania KW - Bartonella elizabethae KW - Mammals KW - Bartonella KW - Genetic diversity KW - Spleen KW - Genotypes KW - DNA KW - Polymerase chain reaction KW - K 03340:Effects of Physical & Chemical Factors KW - J 02410:Animal Diseases KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1113223499?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Identification+of+Diverse+Bartonella+Genotypes+among+Small+Mammals+from+Democratic+Republic+of+Congo+and+Tanzania&rft.au=Gundi%2C+VAKB%3BKosoy%2C+MY%3BMakundi%2C+R+H%3BLaudisoit%2C+A&rft.aulast=Gundi&rft.aufirst=VAKB&rft.date=2012-08-01&rft.volume=87&rft.issue=2&rft.spage=319&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.2012.11-0555 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-10-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Etiology; Spleen; Genetic diversity; Polymerase chain reaction; Genotypes; Mammals; DNA; Bartonella elizabethae; Bartonella; Tanzania DO - http://dx.doi.org/10.4269/ajtmh.2012.11-0555 ER - TY - JOUR T1 - Drug Coverage Surveys for Neglected Tropical Diseases: 10 Years of Field Experience AN - 1113217914; 17254168 AB - Mass drug administration is one of the public health strategies recommended by the World Health Organization for the control and elimination of seven neglected tropical diseases (NTDs). Because adequate coverage is vital to achieve program goals, periodically conducting surveys to validate reported coverage to guide NTD programs is recommended. Over the past decade, the Centers for Disease Control and Prevention (CDC) and collaborators conducted more than 30 two-stage cluster household surveys across three continents. The questionnaires gathered coverage data and information relevant to improving NTD programs including NTD-related attitudes and practices. From the 37 coverage survey estimates obtained in those surveys, 73.3% indicated an over reporting of coverage, including all three that assessed school-based distributions. It took an average of 1 week to conduct a survey. Our experiences led us to conclude that coverage surveys are useful and feasible tools to ensure NTD elimination and control goals are reached. JF - American Journal of Tropical Medicine and Hygiene AU - Worrell, C AU - Mathieu, E AD - Centers for Disease Control and Prevention, Division of Parasitic Diseases, Mail stop F-22, 4770 Buford Highway, NE, Atlanta, GA 30341-3724, USA, emm7@cdc.gov Y1 - 2012/08// PY - 2012 DA - August 2012 SP - 216 EP - 222 VL - 87 IS - 2 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts KW - Inventories KW - Data processing KW - Disease control KW - Public health KW - Attitudes KW - Prevention KW - Continents KW - Households KW - Drugs KW - J 02400:Human Diseases KW - H 12000:Epidemiology and Public Health KW - K 03420:Plant Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1113217914?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Drug+Coverage+Surveys+for+Neglected+Tropical+Diseases%3A+10+Years+of+Field+Experience&rft.au=Worrell%2C+C%3BMathieu%2C+E&rft.aulast=Worrell&rft.aufirst=C&rft.date=2012-08-01&rft.volume=87&rft.issue=2&rft.spage=216&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.2012.12-0167 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-10-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Inventories; Data processing; Disease control; Drugs; Public health; Prevention; Attitudes; Continents; Households DO - http://dx.doi.org/10.4269/ajtmh.2012.12-0167 ER - TY - JOUR T1 - Evidence of Rabies Virus Exposure among Humans in the Peruvian Amazon AN - 1113217896; 17254167 AB - In May of 2010, two communities (Truenococha and Santa Marta) reported to be at risk of vampire bat depredation were surveyed in the Province Datem del Maranon in the Loreto Department of Peru. Risk factors for bat exposure included age less than or equal to 25 years and owning animals that had been bitten by bats. Rabies virus neutralizing antibodies (rVNAs) were detected in 11% (7 of 63) of human sera tested. Rabies virus ribonucleoprotein (RNP) immunoglobulin G (IgG) antibodies were detected in the sera of three individuals, two of whom were also seropositive for rVNA. Rabies virus RNP IgM antibodies were detected in one respondent with no evidence of rVNA or RNP IgG antibodies. Because one respondent with positive rVNA results reported prior vaccination and 86% (six of seven) of rVNA-positive respondents reported being bitten by bats, these data suggest nonfatal exposure of persons to rabies virus, which is likely associated with vampire bat depredation. JF - American Journal of Tropical Medicine and Hygiene AU - Gilbert, A T AU - Petersen, B W AU - Recuenco, S AU - Niezgoda, M AU - Gomez, J AU - Laguna-Torres, V A AU - Rupprecht, C AD - Centers for Disease Control and Prevention, 1600 Clifton Rd, NE, Mailstop G33, Atlanta, GA 30333, USA, fcj6@cdc.gov Y1 - 2012/08// PY - 2012 DA - August 2012 SP - 206 EP - 215 VL - 87 IS - 2 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts; Risk Abstracts KW - Age KW - Mexico, Baja California Sur, Loreto KW - Data processing KW - Vaccination KW - South America, Amazon R. KW - Rabies KW - Risk factors KW - Immunoglobulin G KW - Ribonucleoproteins KW - Peru KW - Rabies virus KW - Colombia, Magdalena, Santa Marta KW - Immunoglobulin M KW - K 03400:Human Diseases KW - J 02350:Immunology KW - R2 23060:Medical and environmental health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1113217896?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Evidence+of+Rabies+Virus+Exposure+among+Humans+in+the+Peruvian+Amazon&rft.au=Gilbert%2C+A+T%3BPetersen%2C+B+W%3BRecuenco%2C+S%3BNiezgoda%2C+M%3BGomez%2C+J%3BLaguna-Torres%2C+V+A%3BRupprecht%2C+C&rft.aulast=Gilbert&rft.aufirst=A&rft.date=2012-08-01&rft.volume=87&rft.issue=2&rft.spage=206&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.2012.11-0689 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-10-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Age; Data processing; Risk factors; Rabies; Ribonucleoproteins; Immunoglobulin G; Vaccination; Immunoglobulin M; Rabies virus; Mexico, Baja California Sur, Loreto; South America, Amazon R.; Peru; Colombia, Magdalena, Santa Marta DO - http://dx.doi.org/10.4269/ajtmh.2012.11-0689 ER - TY - JOUR T1 - NEED FOR PHYSICIAN EDUCATION ON THE BENEFITS AND RISKS OF MALE CIRCUMCISION IN THE UNITED STATES AN - 1069193822; 17114113 AB - Physicians may be called upon to counsel male patients or parents of newborn males regarding their decision to circumcise their newborn sons. The purpose of the present study was to describe physicians who do not understand the benefits and risks associated with male circumcision well enough to counsel parents of newborn male infants and adult men. A self-administered, cross-sectional electronic survey of physicians was conducted in 2008. We analyzed responses from 1,500 physicians (510 family practitioners, 490 internists, 250 pediatricians, and 250 obstetricians/gynecologists). Nearly 22% (n=327/1500) reported they did not understand the risks and benefits of newborn male circumcision well enough to counsel parents and 40.3% (n=504/1250) reported not understanding the risks and benefits well enough to counsel adult men. A substantial minority of physicians may need additional training and/or information about current male circumcision research to feel comfortable counseling parents of newborn male infants or adult men. JF - AIDS Education and Prevention AU - Carbery, Baevin AU - Zhu, Julia AU - Gust, Deborah A AU - Chen, Robert T AU - Kretsinger, Katrina AU - Kilmarx, Peter H AD - HIV Vaccine & Special Studies Team, Epidemiology Branch, Division of HIV/AIDS Prevention, CDC, 1600 Clifton Rd Mail-Stop E-45, Atlanta, GA 30333, dgust@cdc.gov Y1 - 2012/08// PY - 2012 DA - Aug 2012 SP - 377 EP - 387 PB - Guilford Publications, Inc., 72 Spring Street, 4th Floor New York NY 10012 United States VL - 24 IS - 4 SN - 0899-9546, 0899-9546 KW - Risk Abstracts; Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Acquired immune deficiency syndrome KW - Cost-benefit analysis KW - Education KW - Infants KW - Males KW - Neonates KW - Prevention KW - Training KW - USA KW - V 22360:AIDS and HIV KW - H 0500:General KW - R2 23010:General: Models, forecasting UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1069193822?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+Education+and+Prevention&rft.atitle=NEED+FOR+PHYSICIAN+EDUCATION+ON+THE+BENEFITS+AND+RISKS+OF+MALE+CIRCUMCISION+IN+THE+UNITED+STATES&rft.au=Carbery%2C+Baevin%3BZhu%2C+Julia%3BGust%2C+Deborah+A%3BChen%2C+Robert+T%3BKretsinger%2C+Katrina%3BKilmarx%2C+Peter+H&rft.aulast=Carbery&rft.aufirst=Baevin&rft.date=2012-08-01&rft.volume=24&rft.issue=4&rft.spage=377&rft.isbn=&rft.btitle=&rft.title=AIDS+Education+and+Prevention&rft.issn=08999546&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-09-01 N1 - Number of references - 23 N1 - Last updated - 2012-10-19 N1 - SubjectsTermNotLitGenreText - Cost-benefit analysis; Neonates; Infants; Prevention; Acquired immune deficiency syndrome; Education; Training; Males; USA ER - TY - JOUR T1 - Outcomes and follow-up of patients treated for multidrug-resistant tuberculosis in Orel, Russia, 2002-2005 AN - 1038616448; 16979577 AB - SETTING: Multidrug-resistant tuberculosis (MDR-TB) treatment facility, Orel Oblast, Russian Federation. OBJECTIVES: To determine factors associated with poor outcome and to document status of patients after recording of TB outcomes. DESIGN: Retrospective review of prospective single cohort. RESULTS: Among 192 patients, factors significantly associated with poor outcome in multivariate analysis include three or more treatment interruptions during the intensive phase of therapy and alcohol or drug addiction (adjusted OR [aOR] 2.1, 95%CI 1.0-4.3 and aOR 1.9, 95%CI 1.0-3.7). Previous treatment was associated with poor outcome, but only among smear-positive patients (aOR 3.1, 95%CI 1.3-7.3). Ten patients (5%) developed extensively drug-resistant TB (XDR-TB) during treatment; of 115 patients with at least 6 months of follow-up data after outcomes were recorded, 13 (11%) developed XDR-TB. CONCLUSION: Interventions focused on supporting patient adherence during the intensive phase of treatment; the management of drug and alcohol addiction should be developed and studied. A substantial proportion of patients developed XDR-TB during and after treatment. Longer term follow-up data of patients treated for MDR-TB are needed to better inform programmatic policy. JF - International Journal of Tuberculosis and Lung Disease AU - Cavanaugh, J S AU - Kazennyy, B Y AU - Nguyen, M L AU - Kiryanova, E V AU - Vitek, E AU - Khorosheva, T M AU - Nemtsova, E AU - Cegielski, J P AD - National Center for HIV, Hepatitis, STD, and TB Prevention, US Centers for Disease Control and Prevention, 1600 Clifton Rd, NE MS E-10 Atlanta, GA 30333, USA, hgi7@cdc.gov Y1 - 2012/08// PY - 2012 DA - Aug 2012 SP - 1069 EP - 1074 PB - International Union Against Tuberculosis and Lung Disease VL - 16 IS - 8 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology KW - Data processing KW - Mycobacterium KW - Multivariate analysis KW - Drug resistance KW - Lung diseases KW - Tuberculosis KW - Drug addiction KW - Ethanol KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1038616448?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Outcomes+and+follow-up+of+patients+treated+for+multidrug-resistant+tuberculosis+in+Orel%2C+Russia%2C+2002-2005&rft.au=Cavanaugh%2C+J+S%3BKazennyy%2C+B+Y%3BNguyen%2C+M+L%3BKiryanova%2C+E+V%3BVitek%2C+E%3BKhorosheva%2C+T+M%3BNemtsova%2C+E%3BCegielski%2C+J+P&rft.aulast=Cavanaugh&rft.aufirst=J&rft.date=2012-08-01&rft.volume=16&rft.issue=8&rft.spage=1069&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-09-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Data processing; Multivariate analysis; Drug resistance; Lung diseases; Tuberculosis; Drug addiction; Ethanol; Mycobacterium ER - TY - JOUR T1 - Scale-up of isoniazid preventive therapy in PEPFAR-assisted clinical sites in South Africa AN - 1034820308; 16979568 AB - We reviewed the implementation of isoniazid preventive therapy (IPT) in South Africa from January 2010 to March 2011. The South African National Department of Health distributed revised IPT guidelines in May 2010 to increase IPT use in eligible human immunodeficiency virus (HIV) infected patients. We found a dramatic increase in the absolute numbers of patients reported to have been initiated on IPT (from 3309 in January-March 2010 to 49130 in January-March 2011), representing an increase in the proportion (1.0-10.5%) of potentially eligible HIV-infected patients started on IPT. JF - International Journal of Tuberculosis and Lung Disease AU - Bristow, C C AU - Larson, E AU - Vilakazi-Nhlapo, A K AU - Wilson, M AU - Klausner, J D AD - US Centers for Disease Control and Prevention South Africa, PO Box 9536, Pretoria 0001, South Africa, BristowC@sa.cdc.gov Y1 - 2012/08// PY - 2012 DA - Aug 2012 SP - 1020 EP - 1022 PB - International Union Against Tuberculosis and Lung Disease VL - 16 IS - 8 SN - 1027-3719, 1027-3719 KW - Health & Safety Science Abstracts KW - Mycobacterium KW - Human immunodeficiency virus KW - Lung KW - Reviews KW - Guidelines KW - Tuberculosis KW - South Africa KW - H 6000:Natural Disasters/Civil Defense/Emergency Management UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1034820308?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Scale-up+of+isoniazid+preventive+therapy+in+PEPFAR-assisted+clinical+sites+in+South+Africa&rft.au=Bristow%2C+C+C%3BLarson%2C+E%3BVilakazi-Nhlapo%2C+A+K%3BWilson%2C+M%3BKlausner%2C+J+D&rft.aulast=Bristow&rft.aufirst=C&rft.date=2012-08-01&rft.volume=16&rft.issue=8&rft.spage=1020&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-08-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Lung; Human immunodeficiency virus; Reviews; Guidelines; Tuberculosis; Mycobacterium; South Africa ER - TY - JOUR T1 - Predictors of failure in timely tuberculosis treatment completion, United States AN - 1034818468; 16979578 AB - SETTING: The US tuberculosis (TB) surveillance system. OBJECTIVE: To examine failure in timely TB treatment completion to identify interventions toward achieving the national goal of greater than or equal to 93% treatment completion in less than or equal to 12 months among patients eligible for 6-9 month regimens. DESIGN: We examined 1993-2006 trends in timely treatment completion; for 2006 cases, we used Poisson regression to assess predictors for failure in timely completion. RESULTS: Timely treatment completion improved from 64% in 1993 to 84% in 2006, with similar trends among foreign- and US-born persons and racial/ethnic subgroups. Annual increases in timely completion were less than or equal to 1 percentage point during 1998-2006. Subpopulations at highest risk for failure in timely completion were persons with combined pulmonary and extra-pulmonary disease (foreign-born adjusted RR [aRR] 3.25, 95%CI 2.47-4.28; US-born aRR 2.75, 95%CI 1.98-3.83) or incarceration (foreign-born aRR 2.30, 95%CI 1.80-2.93; US-born aRR 1.71, 95%CI 1.36-2.14). Home-lessness and human immunodeficiency virus infection were other risk factors. CONCLUSIONS: Particular attention to timely completion is needed for subpopulations requiring strong medical expertise in TB management and those at risk for treatment non-adherence, especially if foreign-born. Understanding and addressing causes of delayed completion and improving documentation of treatment completion among all cases will be crucial to achieving the US goal. JF - International Journal of Tuberculosis and Lung Disease AU - Mitruka, K AU - Winston, CA AU - Navin, T R AD - Surveillance, Epidemiology, and Outbreak Investigations Branch, Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, 1600 Clifton Road, Mailstop E-10, Atlanta, GA 30333, USA, kmitruka@cdc.gov Y1 - 2012/08// PY - 2012 DA - Aug 2012 SP - 1075 EP - 1082 PB - International Union Against Tuberculosis and Lung Disease VL - 16 IS - 8 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology; Risk Abstracts; Health & Safety Science Abstracts KW - Prisons KW - Mycobacterium KW - Subpopulations KW - Lung diseases KW - Intervention KW - Infection KW - USA KW - Human immunodeficiency virus KW - Lung KW - Risk factors KW - Tuberculosis KW - Ethnic groups KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - J 02400:Human Diseases KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1034818468?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Predictors+of+failure+in+timely+tuberculosis+treatment+completion%2C+United+States&rft.au=Mitruka%2C+K%3BWinston%2C+CA%3BNavin%2C+T+R&rft.aulast=Mitruka&rft.aufirst=K&rft.date=2012-08-01&rft.volume=16&rft.issue=8&rft.spage=1075&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-08-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Risk factors; Subpopulations; Lung diseases; Tuberculosis; Infection; Prisons; Lung; Intervention; Ethnic groups; Mycobacterium; Human immunodeficiency virus; USA ER - TY - JOUR T1 - A Review of the Literature on Event-Level Substance Use and Sexual Risk Behavior Among Men Who Have Sex with Men AN - 1032891086; 16959083 AB - In the United States, there continues to be high incidence of HIV infection among men who have sex with men (MSM), who represent 57% of new infections in 2009. While many studies report associations between non-injection substance use and sexual risk behavior among MSM, overall results are mixed. Summarizing these studies is difficult because researchers have used a variety of assessment periods for substance use and sexual behavior. We review the scientific literature on event-level measures, which assess substance use and sexual risk behavior immediately before or during a sexual encounter and provide the most precise link between these two behaviors. From January 2009 through March 2010, we searched four databases: Ovid (MEDLINE and PsycINFO), Web of Knowledge, and Sociofile. Across studies, results varied by substance with little within substance consistency or a lack of research except for two notable exceptions: methamphetamine and binge alcohol use. The findings underscore the importance of providing HIV risk-reduction interventions for substance-using MSM.Original Abstract: En los Estados Unidos, incidencia alta de la infeccion por VIH entre los hombres que tienen sexo con hombres (HSH) sigue, y HSH representaron 57% de las infecciones nuevas en 2009. Estudios multiples han demostrado que asociaciones existe entre el uso de drogas no inyectables y el comportamiento sexual riesgoso entre HSH. Estudios del uso de drogas y del comportamiento sexual han usado tres tipos de evaluacion (global, circunstancial y nivel del acontecimiento) y han proporcionado resultados variados. Las medidas al nivel del acontecimiento sexual determinan uso de sustancias y comportamiento sexual riesgoso de inmediato antes de o durante el encuentro sexual. Se revsamos la literatura cientifica acerca de la conexion mas precisa entre el uso de drogas y el comportamiento sexual riesgoso, lo cual es evaluacion al nivel del acontecimiento. Desde enero de 2009 hasta marzo de 2010, buscamos en cuatro bases de datos repetidamente: Ovid (MEDLINE y PsycINFO), Web of Knowledge, y Sociofile. Resumimos la investigacion cuantitativa acerca de nivel del acontecimiento, discutimos la consistencia de la evidencia, y recomendamos las direcciones para las investigaciones futuras. Los resultados subrayan la importancia de proporcionar las intervenciones para la reduccion del riesgo por el VIH para HSH que usan drogas. JF - AIDS and Behavior AU - Vosburgh, HWaverly AU - Mansergh, Gordon AU - Sullivan, Patrick S AU - Purcell, David W AD - Division of HIV/AIDS Prevention, Mailstop E37, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Atlanta, GA, 30333, USA, HWVosburgh@cdc.gov Y1 - 2012/08// PY - 2012 DA - Aug 2012 SP - 1394 EP - 1410 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 16 IS - 6 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - Alcohol KW - Acquired immune deficiency syndrome KW - substance use KW - Homosexuality KW - Infection KW - Sexual behavior KW - Databases KW - USA KW - Methamphetamine KW - Literature reviews KW - Human immunodeficiency virus KW - Reviews KW - methamphetamine KW - Sex KW - Ethanol KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1032891086?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=A+Review+of+the+Literature+on+Event-Level+Substance+Use+and+Sexual+Risk+Behavior+Among+Men+Who+Have+Sex+with+Men&rft.au=Vosburgh%2C+HWaverly%3BMansergh%2C+Gordon%3BSullivan%2C+Patrick+S%3BPurcell%2C+David+W&rft.aulast=Vosburgh&rft.aufirst=HWaverly&rft.date=2012-08-01&rft.volume=16&rft.issue=6&rft.spage=1394&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-011-0131-8 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-08-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Databases; Methamphetamine; Literature reviews; Reviews; Infection; Sexual behavior; Ethanol; Sex; Alcohol; Acquired immune deficiency syndrome; Human immunodeficiency virus; substance use; Homosexuality; methamphetamine; USA DO - http://dx.doi.org/10.1007/s10461-011-0131-8 ER - TY - JOUR T1 - An Analysis of Content in Comprehensive Cancer Control Plans that Address Chronic Hepatitis B and C Virus Infections as Major Risk Factors for Liver Cancer AN - 1028028843; 16883076 AB - Chronic hepatitis B and hepatitis C virus (HBV and HCV) infections are among the leading causes of preventable death worldwide. Chronic viral hepatitis is the cause of most primary liver cancer, which is the third leading cause of cancer deaths globally and the ninth leading cause of cancer deaths in the United States. The extent to which comprehensive cancer control (CCC) programs in states, tribal governments and organizations, territories, and Pacific Island jurisdictions address chronic hepatitis B and/or hepatitis C infections as risk factors for liver cancer or recommend interventions for liver cancer prevention in their CCC plans remains unknown. We searched CCC plans for this information using the search tool at http://www.cdc.gov/cancer/ncccp/ to access the content of plans for this information. A combination of key search terms including "liver cancer", "hepatitis", "chronic alcohol", and "alcohol abuse" were used to identify potential content regarding liver cancer risk factors and prevention. Relevant content was abstracted for further review and classification. Of 66 (Although CDC funds 65 programs, one of the Pacific Island Jurisdiction grantees is the Federated States of Micronesia (FSM). This national program supports four FSM states, each of which submits a cancer plan to CDC for a total of 69 plans. During this time period, 66 plans were available on the website.) CCC plans, 27% (n = 18) addressed liver cancer using the above-mentioned search terms. In the 23 plans that addressed HBV and/or HCV, there were 25 goals, objectives, strategies, and outcomes aimed at reducing the incidence or prevalence of HBV and/or HCV infection. While nearly a third of CCC programs identify at least one goal, objective, strategy, outcome, or prevention program to reduce cancer burden in their CCC plans, few plans discuss specific actions needed to reduce the burden of liver cancer. JF - Journal of Community Health AU - Momin, Behnoosh AU - Richardson, Lisa AD - Division of Cancer Prevention and Control, Centers for Disease Prevention and Control, 4770 Buford Highway, MS K-57, Atlanta, GA, 30341, USA, fqv6@cdc.gov Y1 - 2012/08// PY - 2012 DA - Aug 2012 SP - 912 EP - 916 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 37 IS - 4 SN - 0094-5145, 0094-5145 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts; Risk Abstracts KW - Alcohol KW - Cancer KW - Chronic infection KW - Classification KW - Drug abuse KW - Ethanol KW - Hepatitis KW - Hepatitis B KW - Hepatitis C KW - Infection KW - Islands KW - Liver KW - Liver cancer KW - Mortality KW - Prevention KW - Reviews KW - Risk factors KW - Territory KW - hepatitis B KW - ISEW, Caroline I., Micronesia KW - ISEW, Micronesia, Fed. States KW - Hepatitis B virus KW - I, Central Pacific, Pacific Ocean Is. KW - USA KW - Hepatitis C virus KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health KW - V 22310:Genetics, Taxonomy & Structure UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1028028843?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Community+Health&rft.atitle=An+Analysis+of+Content+in+Comprehensive+Cancer+Control+Plans+that+Address+Chronic+Hepatitis+B+and+C+Virus+Infections+as+Major+Risk+Factors+for+Liver+Cancer&rft.au=Momin%2C+Behnoosh%3BRichardson%2C+Lisa&rft.aulast=Momin&rft.aufirst=Behnoosh&rft.date=2012-08-01&rft.volume=37&rft.issue=4&rft.spage=912&rft.isbn=&rft.btitle=&rft.title=Journal+of+Community+Health&rft.issn=00945145&rft_id=info:doi/10.1007%2Fs10900-011-9507-y LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-07-01 N1 - Last updated - 2012-08-24 N1 - SubjectsTermNotLitGenreText - Islands; Classification; Reviews; Risk factors; Liver cancer; Chronic infection; Hepatitis B; Territory; Hepatitis C; Drug abuse; Ethanol; Hepatitis; Alcohol; Mortality; Prevention; Liver; hepatitis B; Infection; Cancer; Hepatitis C virus; Hepatitis B virus; USA; ISEW, Caroline I., Micronesia; I, Central Pacific, Pacific Ocean Is.; ISEW, Micronesia, Fed. States DO - http://dx.doi.org/10.1007/s10900-011-9507-y ER - TY - JOUR T1 - A gel-free proteomic-based method for the characterization of Bordetella pertussis clinical isolates AN - 1028021915; 16815809 AB - Bordetella pertussis (Bp) is the etiologic agent of pertussis or whooping cough, a highly contagious respiratory disease occurring primarily in infants and young children. Although vaccine preventable, pertussis cases have increased over the years leading researchers to re-evaluate vaccine control strategies. Since bacterial outer membrane proteins, comprising the surfaceome, often play roles in pathogenesis and antibody-mediated immunity, three recent Bp circulating isolates were examined using proteomics to identify any potential changes in surface protein expression. Fractions enriched for outer membrane proteins were digested with trypsin and the peptides analyzed by nano liquid chromatography-electrospray ionization-mass spectrometry (nLC-ESI-MS), followed by database analysis to elucidate the surfaceomes of our three Bp isolates. Furthermore, a less labor intensive non-gel based antibody affinity capture technology in conjunction with MS was employed to assess each Bp strains' immunogenic outer membrane proteins. This novel technique is generally applicable allowing for the identification of immunogenic surface expressed proteins on pertussis and other pathogenic bacteria. JF - Journal of Microbiological Methods AU - Williamson, Yulanda M AU - Moura, Hercules AU - Simmons, Kaneatra AU - Whitmon, Jennifer AU - Melnick, Nikkol AU - Rees, Jon AU - Woolfitt, Adrian AU - Schieltz, David M AU - Tondella, Maria L AU - Ades, Edwin AU - Sampson, Jacquelyn AU - Carlone, George AU - Barr, John R AD - Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Chamblee, Georgia 30341, USA, jbarr@cdc.gov Y1 - 2012/08// PY - 2012 DA - Aug 2012 SP - 119 EP - 133 PB - Elsevier B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 90 IS - 2 SN - 0167-7012, 0167-7012 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Clinical isolates KW - Pertussis KW - outer membrane proteins KW - Trypsin KW - Immunity KW - Children KW - Spectrometry KW - Databases KW - Bordetella pertussis KW - Antibodies KW - Immunogenicity KW - proteomics KW - Vaccines KW - Infants KW - A 01300:Methods KW - J 02300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1028021915?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Microbiological+Methods&rft.atitle=A+gel-free+proteomic-based+method+for+the+characterization+of+Bordetella+pertussis+clinical+isolates&rft.au=Williamson%2C+Yulanda+M%3BMoura%2C+Hercules%3BSimmons%2C+Kaneatra%3BWhitmon%2C+Jennifer%3BMelnick%2C+Nikkol%3BRees%2C+Jon%3BWoolfitt%2C+Adrian%3BSchieltz%2C+David+M%3BTondella%2C+Maria+L%3BAdes%2C+Edwin%3BSampson%2C+Jacquelyn%3BCarlone%2C+George%3BBarr%2C+John+R&rft.aulast=Williamson&rft.aufirst=Yulanda&rft.date=2012-08-01&rft.volume=90&rft.issue=2&rft.spage=119&rft.isbn=&rft.btitle=&rft.title=Journal+of+Microbiological+Methods&rft.issn=01677012&rft_id=info:doi/10.1016%2Fj.mimet.2012.04.007 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-07-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Clinical isolates; Pertussis; outer membrane proteins; Trypsin; Immunity; Children; Spectrometry; Databases; Antibodies; Immunogenicity; Vaccines; proteomics; Infants; Bordetella pertussis DO - http://dx.doi.org/10.1016/j.mimet.2012.04.007 ER - TY - JOUR T1 - Induction of pulmonary fibrosis by cerium oxide nanoparticles. AN - 1024937592; 22613087 AB - Cerium compounds have been used as a diesel engine catalyst to lower the mass of diesel exhaust particles, but are emitted as cerium oxide (CeO(2)) nanoparticles in the diesel exhaust. In a previous study, we have demonstrated a wide range of CeO(2)-induced lung responses including sustained pulmonary inflammation and cellular signaling that could lead to pulmonary fibrosis. In this study, we investigated the fibrogenic responses induced by CeO(2) in a rat model at various time points up to 84 days post-exposure. Male Sprague Dawley rats were exposed to CeO(2) by a single intratracheal instillation. Alveolar macrophages (AM) were isolated by bronchial alveolar lavage (BAL). AM-mediated cellular responses, osteopontin (OPN) and transform growth factor (TGF)-β1 in the fibrotic process were investigated. The results showed that CeO(2) exposure significantly increased fibrotic cytokine TGF-β1 and OPN production by AM above controls. The collagen degradation enzymes, matrix metalloproteinase (MMP)-2 and -9 and the tissue inhibitor of MMP were markedly increased in the BAL fluid at 1 day- and subsequently declined at 28 days after exposure, but remained much higher than the controls. CeO(2) induced elevated phospholipids in BAL fluid and increased hydroxyproline content in lung tissue in a dose- and time-dependent manner. Immunohistochemical analysis showed MMP-2, MMP-9 and MMP-10 expressions in fibrotic regions. Morphological analysis noted increased collagen fibers in the lungs exposed to a single dose of 3.5mg/kg CeO(2) and euthanized at 28 days post-exposure. Collectively, our studies show that CeO(2) induced fibrotic lung injury in rats, suggesting it may cause potential health effects. Published by Elsevier Inc. JF - Toxicology and applied pharmacology AU - Ma, Jane Y AU - Mercer, Robert R AU - Barger, Mark AU - Schwegler-Berry, Diane AU - Scabilloni, James AU - Ma, Joseph K AU - Castranova, Vincent AD - Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA. jym1@cdc.gov Y1 - 2012/08/01/ PY - 2012 DA - 2012 Aug 01 SP - 255 EP - 264 VL - 262 IS - 3 KW - Transforming Growth Factor beta1 KW - 0 KW - Osteopontin KW - 106441-73-0 KW - Cerium KW - 30K4522N6T KW - ceric oxide KW - 619G5K328Y KW - Matrix Metalloproteinase 10 KW - EC 3.4.24.22 KW - Matrix Metalloproteinase 2 KW - EC 3.4.24.24 KW - Matrix Metalloproteinase 9 KW - EC 3.4.24.35 KW - Hydroxyproline KW - RMB44WO89X KW - Index Medicus KW - Animals KW - Macrophages, Alveolar -- ultrastructure KW - Dose-Response Relationship, Drug KW - Transforming Growth Factor beta1 -- analysis KW - Lung -- chemistry KW - Macrophages, Alveolar -- drug effects KW - Matrix Metalloproteinase 10 -- analysis KW - Rats KW - Microscopy, Electron, Transmission KW - Rats, Sprague-Dawley KW - Hydroxyproline -- analysis KW - Matrix Metalloproteinase 2 -- analysis KW - Lung -- drug effects KW - Matrix Metalloproteinase 9 -- analysis KW - Osteopontin -- analysis KW - Bronchoalveolar Lavage Fluid -- cytology KW - Male KW - Pulmonary Fibrosis -- chemically induced KW - Nanoparticles -- toxicity KW - Cerium -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1024937592?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+applied+pharmacology&rft.atitle=Induction+of+pulmonary+fibrosis+by+cerium+oxide+nanoparticles.&rft.au=Ma%2C+Jane+Y%3BMercer%2C+Robert+R%3BBarger%2C+Mark%3BSchwegler-Berry%2C+Diane%3BScabilloni%2C+James%3BMa%2C+Joseph+K%3BCastranova%2C+Vincent&rft.aulast=Ma&rft.aufirst=Jane&rft.date=2012-08-01&rft.volume=262&rft.issue=3&rft.spage=255&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+applied+pharmacology&rft.issn=1096-0333&rft_id=info:doi/10.1016%2Fj.taap.2012.05.005 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-10-01 N1 - Date created - 2012-07-13 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: J Toxicol Environ Health A. 1999 Jun 25;57(4):247-66 [10406349] Am J Physiol Lung Cell Mol Physiol. 2004 Jun;286(6):L1311-8 [14977630] J Biol Chem. 1959 Mar;234(3):466-8 [13641241] J Immunol. 2004 Aug 1;173(3):2099-108 [15265946] Am J Physiol Heart Circ Physiol. 2004 Oct;287(4):H1730-9 [15165989] Anal Biochem. 1967 May;19(2):249-55 [6048697] Am Rev Respir Dis. 1978 May;117(5):879-91 [26302] Histochem J. 1979 Jul;11(4):447-55 [91593] Sci Total Environ. 1982 Dec;26(1):19-32 [7167813] Chest. 1983 May;83(5):780-3 [6839821] Respiration. 1987;51 Suppl 1:23-32 [2440083] Med J Aust. 1990 Dec 3-17;153(11-12):726-30 [2247001] FASEB J. 1993 Dec;7(15):1475-82 [8262332] Circ Res. 1994 Feb;74(2):214-24 [8293561] Occup Environ Med. 1994 Mar;51(3):195-9 [8130849] Mod Pathol. 1995 Oct;8(8):859-65 [8552576] Braz J Med Biol Res. 2000 Jul;33(7):749-54 [10881049] Exp Lung Res. 1995 Jan-Feb;21(1):67-77 [7537210] Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6414-9 [9177232] J Immunol. 1998 Jun 1;160(11):5347-54 [9605134] J Biol Chem. 1998 Nov 20;273(47):31262-72 [9813034] Am J Respir Cell Mol Biol. 1999 May;20(5):903-13 [10226060] Am J Physiol Lung Cell Mol Physiol. 2005 Apr;288(4):L709-17 [15608151] Eur J Pharmacol. 2006 Mar 8;533(1-3):133-44 [16487964] Am J Physiol Lung Cell Mol Physiol. 2007 Sep;293(3):L525-34 [17631612] Chest. 2007 Oct;132(4):1311-21 [17934117] Curr Med Chem. 2009;16(11):1400-17 [19355895] Ind Health. 2010;48(1):3-11 [20160402] Toxicol Lett. 2011 Aug 28;205(2):105-15 [21624445] Nanotoxicology. 2011 Sep;5(3):312-25 [20925443] Int J Nanomedicine. 2011;6:2327-35 [22072870] J Toxicol Environ Health A. 1999 Nov 12;58(5):261-78 [10598952] Genes Dev. 2000 Jan 15;14(2):163-76 [10652271] Exp Lung Res. 2000 Mar;26(2):71-88 [10742923] Am J Physiol Lung Cell Mol Physiol. 2000 Sep;279(3):L562-74 [10956632] Am J Respir Cell Mol Biol. 2001 Mar;24(3):264-71 [11245625] J Trace Elem Med Biol. 2001 Apr;14(4):232-6 [11396783] J Environ Pathol Toxicol Oncol. 2001;20 Suppl 1:1-14 [11570667] Nat Genet. 2001 Oct;29(2):117-29 [11586292] J Immunol. 2002 Jun 15;168(12):6470-8 [12055267] Am J Respir Crit Care Med. 1999 Oct;160(4):1274-82 [10508819] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.taap.2012.05.005 ER - TY - JOUR T1 - Medical Risk Factors for Severe West Nile Virus Disease, United States, 2008-2010 AN - 1113223492; 17254165 AB - We conducted enhanced surveillance to identify medical risk factors for severe illness (i.e., hospitalization or death) and neuroinvasive disease (i.e., encephalitis or meningitis) among all West Nile virus disease cases reported from selected states from 2008 to 2010. Of the 1,090 case-patients included in the analysis, 708 (65%) case-patients were hospitalized, 641 (59%) case-patients had neuroinvasive disease, and 55 (5%) case-patients died. Chronic renal disease (adjusted odds ratio [aOR] = 4.1; 95% confidence interval [CI] = 1.4-12.1), history of cancer (aOR = 3.7; 95% CI = 1.8-7.5), history of alcohol abuse (aOR = 3.0; 95% CI = 1.3-6.7), diabetes (aOR = 2.2; 95% CI = 1.4-3.4), and hypertension (aOR = 1.5; 95% CI = 1.1-2.1) were independently associated with severe illness on multivariable analysis. Although the same medical conditions were independently associated with encephalitis, only hypertension was associated with meningitis. The only condition independently associated with death was immune suppression. Prevention messages should be targeted to persons with these conditions. JF - American Journal of Tropical Medicine and Hygiene AU - Lindsey, N P AU - Staples, JE AU - Lehman, JA AU - Fischer, M AD - Arboviral Diseases Branch, Centers for Disease Control and Prevention, 3150 Rampart Road, Fort Collins, CO 80521, USA, frd3@cdc.gov Y1 - 2012/07// PY - 2012 DA - July 2012 SP - 179 EP - 184 VL - 87 IS - 1 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - Mortality KW - Historical account KW - Alcohol KW - Invasiveness KW - Kidney diseases KW - Drug abuse KW - Encephalitis KW - Cancer KW - Meningitis KW - Diabetes mellitus KW - USA KW - Prevention KW - Risk factors KW - West Nile virus KW - Hospitals KW - Hypertension KW - H 11000:Diseases/Injuries/Trauma KW - K 03400:Human Diseases KW - J 02400:Human Diseases KW - R2 23060:Medical and environmental health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1113223492?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Medical+Risk+Factors+for+Severe+West+Nile+Virus+Disease%2C+United+States%2C+2008-2010&rft.au=Lindsey%2C+N+P%3BStaples%2C+JE%3BLehman%2C+JA%3BFischer%2C+M&rft.aulast=Lindsey&rft.aufirst=N&rft.date=2012-07-01&rft.volume=87&rft.issue=1&rft.spage=179&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.2012.12-0113 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-10-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Diabetes mellitus; Invasiveness; Risk factors; Kidney diseases; Drug abuse; Cancer; Encephalitis; Meningitis; Hypertension; Alcohol; Historical account; Mortality; Prevention; Hospitals; West Nile virus; USA DO - http://dx.doi.org/10.4269/ajtmh.2012.12-0113 ER - TY - JOUR T1 - Detection of Mycoplasma pneumoniae and Chlamydophila pneumoniae directly from respiratory clinical specimens using a rapid real-time polymerase chain reaction assay AN - 1038605914; 16834227 AB - We developed a rapid real-time polymerase chain reaction assay for detecting Mycoplasma pneumoniae and Chlamydophila pneumoniae directly from respiratory specimens. This procedure provides over 5 times faster results compared to existing methods while maintaining equivalent detection rates for specimens containing limited target organisms. JF - Diagnostic Microbiology and Infectious Disease AU - Diaz, Maureen H AU - Winchell, Jonas M AD - Respiratory Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA, 30333, USA, jwinchell@cdc.gov Y1 - 2012/07// PY - 2012 DA - July 2012 SP - 278 EP - 280 PB - Elsevier B.V., Box 882 New York NY 10159 United States VL - 73 IS - 3 SN - 0732-8893, 0732-8893 KW - Microbiology Abstracts B: Bacteriology KW - Real-time PCR KW - Community-acquired pneumonia KW - Polymerase chain reaction KW - Chlamydophila pneumoniae KW - Mycoplasma pneumoniae KW - J 02320:Cell Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1038605914?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Diagnostic+Microbiology+and+Infectious+Disease&rft.atitle=Detection+of+Mycoplasma+pneumoniae+and+Chlamydophila+pneumoniae+directly+from+respiratory+clinical+specimens+using+a+rapid+real-time+polymerase+chain+reaction+assay&rft.au=Diaz%2C+Maureen+H%3BWinchell%2C+Jonas+M&rft.aulast=Diaz&rft.aufirst=Maureen&rft.date=2012-07-01&rft.volume=73&rft.issue=3&rft.spage=278&rft.isbn=&rft.btitle=&rft.title=Diagnostic+Microbiology+and+Infectious+Disease&rft.issn=07328893&rft_id=info:doi/10.1016%2Fj.diagmicrobio.2012.03.024 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-09-01 N1 - Last updated - 2016-07-07 N1 - SubjectsTermNotLitGenreText - Polymerase chain reaction; Mycoplasma pneumoniae; Chlamydophila pneumoniae DO - http://dx.doi.org/10.1016/j.diagmicrobio.2012.03.024 ER - TY - JOUR T1 - Haemophilus haemolyticus Isolates Causing Clinical Disease AN - 1038598781; 16874067 AB - We report seven cases of Haemophilus haemolyticus invasive disease detected in the United States, which were previously misidentified as nontypeable Haemophilus influenzae. All cases had different symptoms and presentations. Our study suggests that a testing scheme that includes reliable PCR assays and standard microbiological methods should be used in order to improve H. haemolyticus identification. JF - Journal of Clinical Microbiology AU - Anderson, Raydel AU - Wang, Xin AU - Briere, Elizabeth C AU - Katz, Lee S AU - Cohn, Amanda C AU - Clark, Thomas A AU - Messonnier, Nancy E AU - Mayer, Leonard W AD - Meningitis and Vaccine Preventable Disease Branch, Division of Bacterial Diseases, National Center for Infectious and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, RaydelAnderson,rdo7{at}cdc.gov. Y1 - 2012/07// PY - 2012 DA - Jul 2012 SP - 2462 EP - 2465 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 50 IS - 7 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Haemophilus influenzae KW - Polymerase chain reaction KW - J 02300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1038598781?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Haemophilus+haemolyticus+Isolates+Causing+Clinical+Disease&rft.au=Anderson%2C+Raydel%3BWang%2C+Xin%3BBriere%2C+Elizabeth+C%3BKatz%2C+Lee+S%3BCohn%2C+Amanda+C%3BClark%2C+Thomas+A%3BMessonnier%2C+Nancy+E%3BMayer%2C+Leonard+W&rft.aulast=Anderson&rft.aufirst=Raydel&rft.date=2012-07-01&rft.volume=50&rft.issue=7&rft.spage=2462&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.06575-11 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-09-01 N1 - Number of references - 24 N1 - Last updated - 2013-07-15 N1 - SubjectsTermNotLitGenreText - Polymerase chain reaction; Haemophilus influenzae DO - http://dx.doi.org/10.1128/JCM.06575-11 ER - TY - JOUR T1 - The Economic Burden of All-Terrain Vehicle Related Adult Deaths in the U.S. Workplace, 2003-2006 AN - 1034830757; 17062767 AB - The objective of this study was to estimate the societal economic burden associated with work-related ATV fatalities among civilian persons more than 17 years of age in the U.S. from 2003 through 2006. ATV death data were obtained from the Bureau of Labor Statistics' annual Census of Fatal Occupational Injuries. Costs were estimated using a model employing a cost-of-illness method developed by the National Institute for Occupational Safety and Health. From 2003 to 2006, a total of 129 work-related ATV deaths occurred among persons more than 17 years of age in the U.S., nearly doubling from 20 deaths in 2003 to 39 deaths in 2006. The collective lifetime cost of the deaths was $103.6 million (M), with a four-year mean of $803,100 and a four-year median of $772,100. Decedents age 35 to 54 years accounted for one-third of the deaths (n = 41) at a cost of $50.1 M. Montana had the most deaths (13). Fifty-two percent of the deaths were overturns costing $48.3 M. Eighty-four (65%) of the deaths were workers in agricultural production at a cost of $62.3 M. Short-term investment in prevention measures, such as training and helmets for workers, could provide lasting dividends by preventing work-related ATV deaths and reducing their economic impact. JF - Journal of Agricultural Safety and Health AU - Helmkamp, J C AU - Biddle, E AU - Marsh, S M AU - Campbell, C R AD - NIOSH Western States Office, Denver Federal Center, P.O. Box 25226, Denver, CO 80225-0226, USA, jch4@cdc.gov Y1 - 2012/07// PY - 2012 DA - July 2012 SP - 233 EP - 243 VL - 18 IS - 3 SN - 1074-7583, 1074-7583 KW - Health & Safety Science Abstracts KW - Mortality KW - Age KW - Prevention KW - Training KW - all-terrain vehicles KW - Agricultural production KW - Economics KW - Occupational safety KW - Census KW - USA, Montana KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1034830757?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Agricultural+Safety+and+Health&rft.atitle=The+Economic+Burden+of+All-Terrain+Vehicle+Related+Adult+Deaths+in+the+U.S.+Workplace%2C+2003-2006&rft.au=Helmkamp%2C+J+C%3BBiddle%2C+E%3BMarsh%2C+S+M%3BCampbell%2C+C+R&rft.aulast=Helmkamp&rft.aufirst=J&rft.date=2012-07-01&rft.volume=18&rft.issue=3&rft.spage=233&rft.isbn=&rft.btitle=&rft.title=Journal+of+Agricultural+Safety+and+Health&rft.issn=10747583&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-08-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Mortality; Prevention; Age; all-terrain vehicles; Training; Agricultural production; Occupational safety; Economics; Census; USA, Montana ER - TY - JOUR T1 - Efficacy of HIV/STI Behavioral Interventions for Heterosexual African American Men in the United States: A Meta-Analysis AN - 1034815056; 17048512 AB - This meta-analysis estimates the overall efficacy of HIV prevention interventions to reduce HIV sexual risk behaviors and sexually transmitted infections (STIs) among heterosexual African American men. A comprehensive search of the literature published during 1988-2008 yielded 44 relevant studies. Interventions significantly reduced HIV sexual risk behaviors and STIs. The stratified analysis for HIV sexual risk behaviors indicated that interventions were efficacious for studies specifically targeting African American men and men with incarceration history. In addition, interventions that had provision/referral of medical services, male facilitators, shorter follow-up periods, or emphasized the importance of protecting family and significant others were associated with reductions in HIV sexual risk behaviors. Meta-regression analyses indicated that the most robust intervention component is the provision/referral of medical services. Findings indicate that HIV interventions for heterosexual African American men might be more efficacious if they incorporated a range of health care services rather than HIV/STI-related services alone. JF - AIDS and Behavior AU - Henny, Kirk D AU - Crepaz, Nicole AU - Lyles, Cynthia M AU - Marshall, Khiya J AU - Aupont, Latrina W AU - Jacobs, Elizabeth D AU - Liau, Adrian AU - Rama, Sima AU - Kay, Linda S AU - Willis, Leigh A AU - Charania, Mahnaz R AD - Centers for Disease Control and Prevention, 1600 Clifton Road NE, Mailstop E-37, Atlanta, GA, 30333, USA, cso5@cdc.gov Y1 - 2012/07// PY - 2012 DA - Jul 2012 SP - 1092 EP - 1114 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 16 IS - 5 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - Prisons KW - Acquired immune deficiency syndrome KW - Males KW - Intervention KW - Infection KW - Sexual behavior KW - USA KW - Health care KW - Human immunodeficiency virus KW - Reviews KW - Ethnic groups KW - Sexually transmitted diseases KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1034815056?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Efficacy+of+HIV%2FSTI+Behavioral+Interventions+for+Heterosexual+African+American+Men+in+the+United+States%3A+A+Meta-Analysis&rft.au=Henny%2C+Kirk+D%3BCrepaz%2C+Nicole%3BLyles%2C+Cynthia+M%3BMarshall%2C+Khiya+J%3BAupont%2C+Latrina+W%3BJacobs%2C+Elizabeth+D%3BLiau%2C+Adrian%3BRama%2C+Sima%3BKay%2C+Linda+S%3BWillis%2C+Leigh+A%3BCharania%2C+Mahnaz+R&rft.aulast=Henny&rft.aufirst=Kirk&rft.date=2012-07-01&rft.volume=16&rft.issue=5&rft.spage=1092&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-011-0100-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-08-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Reviews; Infection; Sexual behavior; Prisons; Acquired immune deficiency syndrome; Health care; Human immunodeficiency virus; Males; Intervention; Sexually transmitted diseases; Ethnic groups; USA DO - http://dx.doi.org/10.1007/s10461-011-0100-2 ER - TY - JOUR T1 - Cervical cancer survivors at increased risk of subsequent tobacco-related malignancies, United States 1992-2008 AN - 1028023074; 16828871 AB - Purpose: Persistent smoking among cancer survivors may increase their risk of subsequent malignancies, including tobacco-related malignancies. Despite these risks, nearly 40 % of women diagnosed with cervical cancer continue to smoke after diagnosis. This study describes the relative risk of developing any subsequent and tobacco-related malignancy among cervical cancer survivors. Methods: We examined data from the year 1992 to 2008 in 13 Surveillance, Epidemiology and End Results registries. We calculated the standardized incidence ratio (SIR) and 95 % confidence limits (CLs) for all subsequent and tobacco-related malignancies among cervical cancer survivors. Tobacco-related malignancies were defined according to the 2004 Surgeon General's Report on the Health Consequences of Smoking. For comparison with cervical cancer survivors, SIRs for subsequent malignancies were also calculated for female survivors of breast or colorectal cancers. Results: The SIR of developing a subsequent tobacco-related malignancy was higher among cervical cancer survivors (SIR = 2.2, 95 % CL = 2.0-2.4). Female breast (SIR = 1.1, 95 % CL = 1.0-1.1) and colorectal cancer survivors (1.1, 1.1-1.2) also had an elevated risk. The increased risk of a subsequent tobacco-related malignancy among cervical cancer survivors was greatest in the first 5 years after the initial diagnosis and decreased as time since diagnosis elapsed. Conclusion: Women with cervical cancer have a two-fold increased risk of subsequent tobacco-related malignancies, compared with breast and colorectal cancer survivors. In an effort to decrease their risk of subsequent tobacco-related malignancies, cancer survivors should be targeted for tobacco prevention and cessation services. Special attention should be given to cervical cancer survivors whose risk is almost twice that of breast or colorectal cancer survivors. JF - Cancer Causes & Control AU - Underwood, JMichael AU - Rim, Sun Hee AU - Fairley, Temeika L AU - Tai, Eric AU - Stewart, Sherri L AD - Centers for Disease Control and Prevention, 4770 Buford Highway, N.E., Atlanta, GA, 30341, USA, jmunderwood@cdc.gov Y1 - 2012/07// PY - 2012 DA - Jul 2012 SP - 1009 EP - 1016 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 23 IS - 7 SN - 0957-5243, 0957-5243 KW - Risk Abstracts KW - Smoke KW - Smoking KW - USA KW - Prevention KW - colorectal carcinoma KW - Tobacco KW - Standards KW - Cancer KW - Medical personnel KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1028023074?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cancer+Causes+%26+Control&rft.atitle=Cervical+cancer+survivors+at+increased+risk+of+subsequent+tobacco-related+malignancies%2C+United+States+1992-2008&rft.au=Underwood%2C+JMichael%3BRim%2C+Sun+Hee%3BFairley%2C+Temeika+L%3BTai%2C+Eric%3BStewart%2C+Sherri+L&rft.aulast=Underwood&rft.aufirst=JMichael&rft.date=2012-07-01&rft.volume=23&rft.issue=7&rft.spage=1009&rft.isbn=&rft.btitle=&rft.title=Cancer+Causes+%26+Control&rft.issn=09575243&rft_id=info:doi/10.1007%2Fs10552-012-9957-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-07-01 N1 - Last updated - 2014-05-29 N1 - SubjectsTermNotLitGenreText - Smoke; Smoking; Prevention; colorectal carcinoma; Tobacco; Standards; Medical personnel; Cancer; USA DO - http://dx.doi.org/10.1007/s10552-012-9957-2 ER - TY - JOUR T1 - Evaluation of criteria for the detection of fires in underground conveyor belt haulageways AN - 1020848415; 16792451 AB - Large-scale experiments were conducted in an above-ground gallery to simulate typical fires that develop along conveyor belt transport systems within underground coal mines. In the experiments, electrical strip heaters, imbedded similar to 5cm below the top surface of a large mass of coal rubble, were used to ignite the coal, producing an open flame. The flaming coal mass subsequently ignited 1.83-m-wide conveyor belts located approximately 0.30m above the coal surface. Gas samples were drawn through an averaging probe located approximately 20m downstream of the coal for continuous measurement of CO, CO2, and O2 as the fire progressed through the stages of smoldering coal, flaming coal, and flaming conveyor belt. Also located approximately 20m from the fire origin and approximately 0.5m below the roof of the gallery were two commercially available smoke detectors, a light obscuration meter, and a sampling probe for measurement of total mass concentration of smoke particles. Located upstream of the fire origin and also along the wall of the gallery at approximately 14m and 5m upstream were two video cameras capable of both smoke and flame detection. During the experiments, alarm times of the smoke detectors and video cameras were measured while the smoke obscuration and total smoke mass were continually measured. Twelve large-scale experiments were conducted using three different types of fire-resistant conveyor belts and four air velocities for each belt. The air velocities spanned the range from 1.0m/s to 6.9m/s. The results of these experiments are compared to previous large-scale results obtained using a smaller fire gallery and much narrower (1.07-m) conveyor belts to determine if the fire detection criteria previously developed remained valid for the wider conveyor belts. Although some differences between these and the previous experiments did occur, the results, in general, compare very favorably. Differences are duly noted and their impact on fire detection discussed. JF - Fire Safety Journal AU - Litton, Charles D AU - Perera, Inoka Eranda AD - National Institute for Occupational Safety and Health (NIOSH), Office of Mine Safety and Health Research (OMSHR), 626 Cochrans Mill Road, P.O. Box 18070, Pittsburgh, PA 15236, United States, chl3@cdc.gov Y1 - 2012/07// PY - 2012 DA - Jul 2012 SP - 110 EP - 119 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 51 SN - 0379-7112, 0379-7112 KW - Health & Safety Science Abstracts KW - Fires KW - Fire detection KW - Smoke KW - Smoke sensors KW - Gas sensors KW - galleries KW - Velocity KW - Upstream KW - Downstream KW - Coal KW - Particulates KW - Carbon dioxide KW - H 2000:Transportation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1020848415?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Fire+Safety+Journal&rft.atitle=Evaluation+of+criteria+for+the+detection+of+fires+in+underground+conveyor+belt+haulageways&rft.au=Litton%2C+Charles+D%3BPerera%2C+Inoka+Eranda&rft.aulast=Litton&rft.aufirst=Charles&rft.date=2012-07-01&rft.volume=51&rft.issue=&rft.spage=110&rft.isbn=&rft.btitle=&rft.title=Fire+Safety+Journal&rft.issn=03797112&rft_id=info:doi/10.1016%2Fj.firesaf.2012.04.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-06-01 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Smoke; galleries; Fires; Upstream; Velocity; Downstream; Particulates; Coal; Carbon dioxide DO - http://dx.doi.org/10.1016/j.firesaf.2012.04.004 ER - TY - CPAPER T1 - CDC's Health Water Program and the Evolution of the Toolbox T2 - 131st Annual Conference and Exposition of the American Water Works Association (ACE12) AN - 1313005652; 6119827 JF - 131st Annual Conference and Exposition of the American Water Works Association (ACE12) AU - Miller, Mark Y1 - 2012/06/10/ PY - 2012 DA - 2012 Jun 10 KW - Evolution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313005652?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=131st+Annual+Conference+and+Exposition+of+the+American+Water+Works+Association+%28ACE12%29&rft.atitle=CDC%27s+Health+Water+Program+and+the+Evolution+of+the+Toolbox&rft.au=Miller%2C+Mark&rft.aulast=Miller&rft.aufirst=Mark&rft.date=2012-06-10&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=131st+Annual+Conference+and+Exposition+of+the+American+Water+Works+Association+%28ACE12%29&rft.issn=&rft_id=info:doi/ L2 - http://apps.awwa.org/ebusmain/default.aspx?tabid=265&viewer=dates&meetingid=A12 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - JOUR T1 - Evaluation and Comparison of Urinary Metabolic Biomarkers of Exposure for the Jet Fuel JP-8 AN - 1285103592; 17589649 AB - A study of workers exposed to jet fuel propellant 8 (JP-8) was conducted at U.S. Air Force bases and included the evaluation of three biomarkers of exposure: S-benzylmercapturic acid (BMA), S-phenylmercapturic acid (PMA), and (2-methoxyethoxy)acetic acid (MEAA). Postshift urine specimens were collected from various personnel categorized as high (n = 98), moderate (n = 38) and low (n = 61) JP-8 exposure based on work activities. BMA and PMA urinary levels were determined by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS), and MEAA urinary levels were determined by gas chromatography-mass spectrometry (GC-MS). The numbers of samples determined as positive for the presence of the BMA biomarker (above the test method's limit of detection [LOD = 0.5 ng/ml]) were 96 (98.0%), 37 (97.4%), and 58 (95.1%) for the high, moderate, and low (control) exposure workgroup categories, respectively. The numbers of samples determined as positive for the presence of the PMA biomarker (LOD = 0.5 ng/ml) were 33 (33.7%), 9 (23.7%), and 12 (19.7%) for the high, moderate, and low exposure categories. The numbers of samples determined as positive for the presence of the MEAA biomarker (LOD = 0.1 mu g/ml) were 92 (93.4%), 13 (34.2%), and 2 (3.3%) for the high, moderate, and low exposure categories. Statistical analysis of the mean levels of the analytes demonstrated MEAA to be the most accurate or appropriate biomarker for JP-8 exposure using urinary concentrations either adjusted or not adjusted for creatinine; mean levels of BMA and PMA were not statistically significant between workgroup categories after adjusting for creatinine. JF - Journal of Toxicology and Environmental Health, Part A: Current Issues AU - B'Hymer, Clayton AU - Krieg, Edward Jr AU - Cheever, Kenneth L AU - Toennis, Christine A AU - Clark, John C AU - Kesner, James S AU - Gibson, Roger AU - Butler, Mary Ann AD - National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Division of Applied Research and Technology, Taft Laboratory, Cincinnati, Ohio, USA, CBHymer@cdc.gov Y1 - 2012/06/01/ PY - 2012 DA - 2012 Jun 01 SP - 661 EP - 672 PB - Taylor & Francis Group Ltd., 2 Park Square Oxford OX14 4RN United Kingdom VL - 75 IS - 11 SN - 1528-7394, 1528-7394 KW - Health & Safety Science Abstracts; Pollution Abstracts; Environment Abstracts; Water Resources Abstracts; Aqualine Abstracts; Toxicology Abstracts KW - Mass Spectrometry KW - Phorbol esters KW - Fuels KW - Propellants KW - Statistical analysis KW - Mass spectrometry KW - Mass spectroscopy KW - Evaluation KW - Personnel KW - Gas chromatography KW - Exposure KW - Statistical Analysis KW - Fuel KW - Occupational exposure KW - Bioindicators KW - biomarkers KW - Spectrometry KW - USA KW - Creatinine KW - Urine KW - Acids KW - SW 5080:Evaluation, processing and publication KW - AQ 00008:Effects of Pollution KW - X 24360:Metals KW - H 1000:Occupational Safety and Health KW - P 6000:TOXICOLOGY AND HEALTH KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1285103592?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.atitle=Evaluation+and+Comparison+of+Urinary+Metabolic+Biomarkers+of+Exposure+for+the+Jet+Fuel+JP-8&rft.au=B%27Hymer%2C+Clayton%3BKrieg%2C+Edward+Jr%3BCheever%2C+Kenneth+L%3BToennis%2C+Christine+A%3BClark%2C+John+C%3BKesner%2C+James+S%3BGibson%2C+Roger%3BButler%2C+Mary+Ann&rft.aulast=B%27Hymer&rft.aufirst=Clayton&rft.date=2012-06-01&rft.volume=75&rft.issue=11&rft.spage=661&rft.isbn=&rft.btitle=&rft.title=Journal+of+Toxicology+and+Environmental+Health%2C+Part+A%3A+Current+Issues&rft.issn=15287394&rft_id=info:doi/10.1080%2F15287394.2012.688483 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-01 N1 - Last updated - 2015-04-09 N1 - SubjectsTermNotLitGenreText - Creatinine; Phorbol esters; Gas chromatography; Personnel; Urine; Fuels; Statistical analysis; biomarkers; Mass spectroscopy; Bioindicators; Propellants; Mass spectrometry; Occupational exposure; Spectrometry; Evaluation; Mass Spectrometry; Acids; Exposure; Statistical Analysis; Fuel; USA DO - http://dx.doi.org/10.1080/15287394.2012.688483 ER - TY - JOUR T1 - Impact of Indoor Residual Spraying with Lambda-Cyhalothrin on Malaria Parasitemia and Anemia Prevalence among Children Less than Five Years of Age in an Area of Intense, Year-Round Transmission in Malawi AN - 1113220855; 17254126 AB - Little is known about the impact of indoor residual spraying (IRS) in areas with intense malaria transmission such as sub-Saharan Africa. In Malawi, IRS with lambda-cyhalothrin has been applied annually in an area of intense year-long transmission since 2007. We evaluated the impact of IRS on parasitemia and anemia prevalence in children less than five years of age by using a cross-sectional household survey conducted in 2009, six months after the second IRS spray round. We measured malaria parasitemia and anemia (hemoglobin level < 11 g/dL) in 899 children less than five years of age and used binomial regression to assess the impact of IRS by comparing children living in a household sprayed with IRS (direct IRS) with those in a household not sprayed with IRS, but in an IRS area (indirect IRS) and those living in a household not sprayed with IRS and not in an IRS area (no IRS). In the IRS area, 77% of households reported receiving IRS. Adjusting for bed net use, house construction, and socioeconomic status, we found that receiving direct IRS and indirect IRS were significantly associated with a 33% (95% confidence interval [CI] = 1-54%) and 46% (95% CI = 20-64%) reduction in parasitemia and a 21% (95% CI = 4-34%) and 30% (95% CI = 12-45%) reduction in anemia prevalence, respectively. JF - American Journal of Tropical Medicine and Hygiene AU - Skarbinski, J AU - Mwandama, D AU - Wolkon, A AU - Luka, M AU - Jafali, J AU - Smith, A AU - Mzilahowa, T AU - Gimnig, J AU - Campbell, C AU - Chiphwanya, J AU - Ali, D AU - Mathanga, D P AD - Malaria Branch, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Mailstop F22, Atlanta, GA 30341, USA, jskarbinski@cdc.gov Y1 - 2012/06// PY - 2012 DA - June 2012 SP - 997 EP - 1004 VL - 86 IS - 6 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts B: Bacteriology; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Microbiology Abstracts C: Algology, Mycology & Protozoology; Health & Safety Science Abstracts KW - Age KW - Human diseases KW - Housing KW - Socioeconomics KW - Malaria KW - Spraying KW - Public health KW - Hemoglobin KW - Malawi KW - Houses KW - Sprays KW - Anemia KW - Children KW - Socio-economic aspects KW - parasitemia KW - Anaemia KW - Households KW - Spray KW - Residential areas KW - Hygiene KW - Haemoglobins KW - K 03400:Human Diseases KW - J 02400:Human Diseases KW - Q1 08485:Species interactions: pests and control KW - Q5 08524:Public health, medicines, dangerous organisms KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1113220855?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Impact+of+Indoor+Residual+Spraying+with+Lambda-Cyhalothrin+on+Malaria+Parasitemia+and+Anemia+Prevalence+among+Children+Less+than+Five+Years+of+Age+in+an+Area+of+Intense%2C+Year-Round+Transmission+in+Malawi&rft.au=Skarbinski%2C+J%3BMwandama%2C+D%3BWolkon%2C+A%3BLuka%2C+M%3BJafali%2C+J%3BSmith%2C+A%3BMzilahowa%2C+T%3BGimnig%2C+J%3BCampbell%2C+C%3BChiphwanya%2C+J%3BAli%2C+D%3BMathanga%2C+D+P&rft.aulast=Skarbinski&rft.aufirst=J&rft.date=2012-06-01&rft.volume=86&rft.issue=6&rft.spage=997&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.2012.11-0621 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-10-01 N1 - Last updated - 2016-09-29 N1 - SubjectsTermNotLitGenreText - Human diseases; Anaemia; Spray; Malaria; Hygiene; Haemoglobins; Public health; Hemoglobin; Socio-economic aspects; Houses; Age; parasitemia; Anemia; Spraying; Children; Housing; Households; Sprays; Residential areas; Socioeconomics; Malawi DO - http://dx.doi.org/10.4269/ajtmh.2012.11-0621 ER - TY - JOUR T1 - Fatal Case of Brucellosis Misdiagnosed in Early Stages of Brucella suis Infection in a 46-Year-Old Patient with Marfan Syndrome AN - 1038598007; 16833490 AB - We report a fatal case of Brucella suis endocarditis initially misdiagnosed by automated identification systems as Ochrobactrum anthropi infection in a patient with a history of Marfan syndrome and recreational feral swine hunting. This report emphasizes the need to consider brucellosis as a part of the differential diagnosis of acute febrile illness, particularly in patients with known risk of exposure. JF - Journal of Clinical Microbiology AU - Carrington, M AU - Choe, U AU - Ubillos, S AU - Stanek, D AU - Campbell, M AU - Wansbrough, L AU - Lee, P AU - Churchwell, G AU - Rosas, K AU - Zaki AD - University of South Florida, Tampa, Florida, USA, B.K.De,bkd1{at}cdc.gov. Y1 - 2012/06// PY - 2012 DA - Jun 2012 SP - 2173 EP - 2175 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 50 IS - 6 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Marfan's syndrome KW - Differential diagnosis KW - Brucella suis KW - Ochrobactrum anthropi KW - Infection KW - Connective tissue diseases KW - Brucellosis KW - Hunting KW - Endocarditis KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1038598007?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Fatal+Case+of+Brucellosis+Misdiagnosed+in+Early+Stages+of+Brucella+suis+Infection+in+a+46-Year-Old+Patient+with+Marfan+Syndrome&rft.au=Carrington%2C+M%3BChoe%2C+U%3BUbillos%2C+S%3BStanek%2C+D%3BCampbell%2C+M%3BWansbrough%2C+L%3BLee%2C+P%3BChurchwell%2C+G%3BRosas%2C+K%3BZaki&rft.aulast=Carrington&rft.aufirst=M&rft.date=2012-06-01&rft.volume=50&rft.issue=6&rft.spage=2173&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.00573-12 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-09-01 N1 - Number of references - 27 N1 - Last updated - 2013-07-15 N1 - SubjectsTermNotLitGenreText - Marfan's syndrome; Differential diagnosis; Hunting; Brucellosis; Connective tissue diseases; Infection; Endocarditis; Brucella suis; Ochrobactrum anthropi DO - http://dx.doi.org/10.1128/JCM.00573-12 ER - TY - JOUR T1 - Innovations in modeling influenza virus infections in the laboratory AN - 1032901742; 16815472 AB - Respiratory viruses represent one of the most substantial infectious disease burdens to the human population today, and in particular, seasonal and pandemic influenza viruses pose a persistent threat to public health worldwide. In recent years, advances in techniques used in experimental research have provided the means to better understand the mechanisms of pathogenesis and transmission of respiratory viruses, and thus more accurately model these infections in the laboratory. Here, we briefly review the model systems used to study influenza virus infections, and focus particularly on recent advances that have increased our knowledge of these formidable respiratory pathogens. JF - Trends in Microbiology AU - Gustin, Kortney M AU - Belser, Jessica A AU - Katz, Jacqueline M AU - Tumpey, Terrence M AU - Maines, Taronna R AD - Influenza Division, National Center for Immunization and Respiratory Disease, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA, tmaines@cdc.gov PY - 2012 SP - 275 EP - 281 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 20 IS - 6 SN - 0966-842X, 0966-842X KW - Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts KW - influenza virus KW - animal models KW - bioaerosol KW - transmission KW - Influenza KW - pandemics KW - Influenza virus KW - Infectious diseases KW - Reviews KW - Pathogens KW - Infection KW - Public health KW - Models KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1032901742?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Trends+in+Microbiology&rft.atitle=Innovations+in+modeling+influenza+virus+infections+in+the+laboratory&rft.au=Gustin%2C+Kortney+M%3BBelser%2C+Jessica+A%3BKatz%2C+Jacqueline+M%3BTumpey%2C+Terrence+M%3BMaines%2C+Taronna+R&rft.aulast=Gustin&rft.aufirst=Kortney&rft.date=2012-06-01&rft.volume=20&rft.issue=6&rft.spage=275&rft.isbn=&rft.btitle=&rft.title=Trends+in+Microbiology&rft.issn=0966842X&rft_id=info:doi/10.1016%2Fj.tim.2012.03.006 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-08-01 N1 - Last updated - 2016-01-06 N1 - SubjectsTermNotLitGenreText - Influenza; pandemics; Infectious diseases; Reviews; Pathogens; Infection; Models; Public health; Influenza virus DO - http://dx.doi.org/10.1016/j.tim.2012.03.006 ER - TY - JOUR T1 - Does Tetanus-Diphtheria-Acellular Pertussis Vaccination Interfere with Serodiagnosis of Pertussis Infection? AN - 1028026516; 16833560 AB - An anti-pertussis toxin (PT) IgG enzyme-linked immunosorbent assay (ELISA) was analytically validated for the diagnosis of pertussis at a cutoff of 94 ELISA units (EU)/ml. Little was known about the performance of this ELISA in the diagnosis of adults recently vaccinated with tetanus-diphtheria-acellular pertussis (Tdap) vaccine, which contains PT. The goal of this study was to determine when the assay can be used following Tdap vaccination. A cohort of 102 asymptomatic health care personnel (HCP) vaccinated with Tdap (Adacel; Sanofi Pasteur) were aged 19 to 79 years (median, 47 years) at vaccination. For each HCP, specimens were available for evaluation at 2 to 10 time points (prevaccination to 24 months postvaccination), and geometric mean concentrations (GMC) for the cohort were calculated at each time point. Among 97 HCP who responded to vaccination, a mixed-model analysis with prediction and tolerance intervals was performed to estimate the time at which serodiagnosis can be used following vaccination. The GMCs were 8, 21, and 9 EU/ml at prevaccination and 4 and 12 months postvaccination, respectively. Eight (8%) of the 102 HCP reached antibody titers of greater than or equal to 94 EU/ml during their peak response, but none had these titers by 6 months postvaccination. The calculated prediction and tolerance intervals were <94 EU/ml by 45 and 75 days postvaccination, respectively. Tdap vaccination 6 months prior to testing did not confound result interpretation. This seroassay remains a valuable diagnostic tool for adult pertussis. JF - Clinical and Vaccine Immunology AU - Pawloski, Lucia C AU - Kirkland, Kathryn B AU - Baughman, Andrew L AU - Martin, Monte D AU - Talbot, Elizabeth A AU - Messonnier, Nancy E AU - Lucia Tondella, Maria AD - Centers for Disease Control and Prevention, Atlanta, Georgia, USA, LuciaC.Pawloski,lpawloski{at}cdc.gov. Y1 - 2012/06// PY - 2012 DA - Jun 2012 SP - 875 EP - 880 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 19 IS - 6 SN - 1556-679X, 1556-679X KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Enzyme-linked immunosorbent assay KW - Immunoglobulin G KW - Immunological tolerance KW - Infection KW - Personnel KW - Pertussis KW - Toxins KW - Vaccination KW - Vaccines UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1028026516?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+and+Vaccine+Immunology&rft.atitle=Does+Tetanus-Diphtheria-Acellular+Pertussis+Vaccination+Interfere+with+Serodiagnosis+of+Pertussis+Infection%3F&rft.au=Pawloski%2C+Lucia+C%3BKirkland%2C+Kathryn+B%3BBaughman%2C+Andrew+L%3BMartin%2C+Monte+D%3BTalbot%2C+Elizabeth+A%3BMessonnier%2C+Nancy+E%3BLucia+Tondella%2C+Maria&rft.aulast=Pawloski&rft.aufirst=Lucia&rft.date=2012-06-01&rft.volume=19&rft.issue=6&rft.spage=875&rft.isbn=&rft.btitle=&rft.title=Clinical+and+Vaccine+Immunology&rft.issn=1556679X&rft_id=info:doi/10.1128%2FCVI.05686-11 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-07-01 N1 - Number of references - 29 N1 - Last updated - 2012-09-24 N1 - SubjectsTermNotLitGenreText - Pertussis; Enzyme-linked immunosorbent assay; Personnel; Immunoglobulin G; Vaccines; Infection; Immunological tolerance; Vaccination; Toxins DO - http://dx.doi.org/10.1128/CVI.05686-11 ER - TY - JOUR T1 - Mechanisms of carbon nanotube-induced toxicity: focus on oxidative stress. AN - 1015246426; 22513272 AB - Nanotechnologies are emerging as highly promising technologies in many sectors in the society. However, the increasing use of engineered nanomaterials also raises concerns about inadvertent exposure to these materials and the potential for adverse effects on human health and the environment. Despite several years of intensive investigations, a common paradigm for the understanding of nanoparticle-induced toxicity remains to be firmly established. Here, the so-called oxidative stress paradigm is scrutinized. Does oxidative stress represent a secondary event resulting inevitably from disruption of biochemical processes and the demise of the cell, or a specific, non-random event that plays a role in the induction of cellular damage e.g. apoptosis? The answer to this question will have important ramifications for the development of strategies for mitigation of adverse effects of nanoparticles. Recent examples of global lipidomics studies of nanoparticle-induced tissue damage are discussed along with proteomics and transcriptomics approaches to achieve a comprehensive understanding of the complex and interrelated molecular changes in cells and tissues exposed to nanoparticles. We also discuss instances of non-oxidative stress-mediated cellular damage resulting from direct physical interference of nanomaterials with cellular structures. Published by Elsevier Inc. JF - Toxicology and applied pharmacology AU - Shvedova, Anna A AU - Pietroiusti, Antonio AU - Fadeel, Bengt AU - Kagan, Valerian E AD - Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, University of Rome Tor Vergata, Rome, Italy. ats1@cdc.gov Y1 - 2012/06/01/ PY - 2012 DA - 2012 Jun 01 SP - 121 EP - 133 VL - 261 IS - 2 KW - Nanotubes, Carbon KW - 0 KW - Index Medicus KW - Humans KW - Apoptosis -- drug effects KW - Lipid Peroxidation -- drug effects KW - Nanoparticles -- toxicity KW - Phagocytes -- physiology KW - Oxidative Stress -- drug effects KW - Nanotubes, Carbon -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1015246426?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+applied+pharmacology&rft.atitle=Mechanisms+of+carbon+nanotube-induced+toxicity%3A+focus+on+oxidative+stress.&rft.au=Shvedova%2C+Anna+A%3BPietroiusti%2C+Antonio%3BFadeel%2C+Bengt%3BKagan%2C+Valerian+E&rft.aulast=Shvedova&rft.aufirst=Anna&rft.date=2012-06-01&rft.volume=261&rft.issue=2&rft.spage=121&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+applied+pharmacology&rft.issn=1096-0333&rft_id=info:doi/10.1016%2Fj.taap.2012.03.023 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-07-23 N1 - Date created - 2012-05-21 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Chem Commun (Camb). 2011 Oct 7;47(37):10182-8 [21776531] ACS Nano. 2011 Sep 27;5(9):7342-53 [21800898] ACS Nano. 2011 Sep 27;5(9):6861-70 [21800904] Biochem Biophys Res Commun. 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[21177774] Nanomedicine (Lond). 2011 Jan;6(1):143-56 [21182425] ACS Nano. 2010 Dec 28;4(12):7508-14 [21080666] Toxicol Sci. 2011 Mar;120(1):123-35 [21135415] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.taap.2012.03.023 ER - TY - JOUR T1 - Increasing rates of vibriosis in the United States, 1996-2010: review of surveillance data from 2 systems. AN - 1015093322; 22572659 AB - The Centers for Disease Control and Prevention monitors vibriosis through 2 surveillance systems: the nationwide Cholera and Other Vibrio Illness Surveillance (COVIS) system and the 10-state Foodborne Diseases Active Surveillance Network (FoodNet). COVIS conducts passive surveillance and FoodNet conducts active surveillance for laboratory-confirmed Vibrio infections. We summarized Vibrio infections (excluding toxigenic V. cholerae O1 and O139) reported to COVIS and FoodNet from 1996 through 2010. For each system, we calculated incidence rates using US Census Bureau population estimates for the surveillance area. From 1996 to 2010, 7700 cases of vibriosis were reported to COVIS and 1519 to FoodNet. Annual incidence of reported vibriosis per 100,000 population increased from 1996 to 2010 in both systems, from 0.09 to 0.28 in COVIS and from 0.15 to 0.42 in FoodNet. The 3 commonly reported Vibrio species were V. parahaemolyticus, V. vulnificus, and V. alginolyticus; both surveillance systems showed that the incidence of each increased. In both systems, most hospitalizations and deaths were caused by V. vulnificus infection, and most patients were white men. The number of cases peaked in the summer months. Surveillance data from both COVIS and FoodNet indicate that the incidence of vibriosis increased from 1996 to 2010 overall and for each of the 3 most commonly reported species. Epidemiologic patterns were similar in both systems. Current prevention efforts have failed to prevent increasing rates of vibriosis; more effective efforts will be needed to decrease rates. JF - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America AU - Newton, Anna AU - Kendall, Magdalena AU - Vugia, Duc J AU - Henao, Olga L AU - Mahon, Barbara E AD - Enteric Diseases Epidemiology Branch, Division of Foodborne, Waterborne, and Environmental Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30033, USA. aenewton@cdc.gov Y1 - 2012/06// PY - 2012 DA - June 2012 SP - S391 EP - S395 VL - 54 Suppl 5 KW - Index Medicus KW - Young Adult KW - Centers for Disease Control and Prevention (U.S.) KW - Humans KW - Vibrio cholerae -- isolation & purification KW - Vibrio alginolyticus -- isolation & purification KW - Aged KW - Child KW - Vibrio parahaemolyticus -- isolation & purification KW - Child, Preschool KW - Infant KW - Hospitalization KW - Aged, 80 and over KW - Seasons KW - Adult KW - Incidence KW - Seawater -- microbiology KW - Middle Aged KW - Adolescent KW - United States -- epidemiology KW - Vibrio vulnificus -- isolation & purification KW - Male KW - Female KW - Foodborne Diseases -- epidemiology KW - Vibrio Infections -- microbiology KW - Foodborne Diseases -- microbiology KW - Vibrio Infections -- epidemiology KW - Vibrio -- isolation & purification KW - Population Surveillance UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1015093322?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+infectious+diseases+%3A+an+official+publication+of+the+Infectious+Diseases+Society+of+America&rft.atitle=Increasing+rates+of+vibriosis+in+the+United+States%2C+1996-2010%3A+review+of+surveillance+data+from+2+systems.&rft.au=Newton%2C+Anna%3BKendall%2C+Magdalena%3BVugia%2C+Duc+J%3BHenao%2C+Olga+L%3BMahon%2C+Barbara+E&rft.aulast=Newton&rft.aufirst=Anna&rft.date=2012-06-01&rft.volume=54+Suppl+5&rft.issue=&rft.spage=S391&rft.isbn=&rft.btitle=&rft.title=Clinical+infectious+diseases+%3A+an+official+publication+of+the+Infectious+Diseases+Society+of+America&rft.issn=1537-6591&rft_id=info:doi/10.1093%2Fcid%2Fcis243 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-10-25 N1 - Date created - 2012-05-10 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: J Infect Dis. 2000 May;181(5):1661-6 [10823766] Epidemiol Infect. 2000 Jun;124(3):489-95 [10982073] Clin Infect Dis. 2008 Apr 1;46(7):970-6 [18444811] J Food Prot. 2009 Oct;72(10):2110-3 [19833034] Emerg Infect Dis. 2011 Jan;17(1):7-15 [21192848] ISME J. 2012 Jan;6(1):21-30 [21753799] Clin Infect Dis. 2011 Mar 15;52(6):788-92 [21367733] Int J Infect Dis. 2011 Mar;15(3):e157-66 [21177133] J Water Health. 2011 Dec;9(4):680-94 [22048428] Vet Microbiol. 2010 Jan 27;140(3-4):310-7 [19342185] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1093/cid/cis243 ER - TY - JOUR T1 - Release of beryllium from mineral ores in artificial lung and skin surface fluids AN - 1008845715; 16540549 AB - Exposure to some manufactured beryllium compounds via skin contact or inhalation can cause sensitization. A portion of sensitized persons who inhale beryllium may develop chronic beryllium disease (CBD). Little is understood about exposures to naturally occurring beryllium minerals. The purpose of this study was to assess the bioaccessibility of beryllium from bertrandite ore. Dissolution of bertrandite from two mine pits (Monitor and Blue Chalk) was evaluated for both the dermal and inhalation exposure pathways by determining bioaccessibility in artificial sweat (pH 5.3 and pH 6.5), airway lining fluid (SUF, pH 7.3), and alveolar macrophage phagolysosomal fluid (PSF, pH 4.5). Significantly more beryllium was released from Monitor pit ore than Blue Chalk pit ore in artificial sweat buffered to pH 5.3 (0.88 plus or minus 0.01% vs. 0.36 plus or minus 0.00%) and pH 6.5 (0.09 plus or minus 0.00% vs. 0.03 plus or minus 0.01%). Rates of beryllium released from the ores in artificial sweat were faster than previously measured for manufactured forms of beryllium (e.g., beryllium oxide), known to induce sensitization in mice. In SUF, levels of beryllium were below the analytical limit of detection. In PSF, beryllium dissolution was biphasic (initial rapid diffusion followed by latter slower surface reactions). During the latter phase, dissolution half-times were 1,400 to 2,000 days, and rate constants were ~7 10 super(-10) g/(cm super(2).day), indicating that bertrandite is persistent in the lung. These data indicate that it is prudent to control skin and inhalation exposures to bertrandite dusts. JF - Environmental Geochemistry and Health AU - Duling, Matthew G AU - Stefaniak, Aleksandr B AU - Lawrence, Robert B AU - Chipera, Steve J AU - Abbas Virji, M AD - Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV, 26505, USA, AStefaniak@cdc.gov Y1 - 2012/06// PY - 2012 DA - Jun 2012 SP - 313 EP - 322 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 34 IS - 3 SN - 0269-4042, 0269-4042 KW - Ecology Abstracts; Environment Abstracts; Water Resources Abstracts KW - Macrophages KW - Inhalation KW - Sweat KW - Dust KW - Ores KW - Exposure KW - oxides KW - Diffusion KW - Beryllium compounds KW - pH effects KW - pH KW - Respiratory tract KW - Berylliosis KW - Skin KW - Data processing KW - Geochemistry KW - Hydrogen Ion Concentration KW - Mice KW - Linings KW - Mines KW - Dusts KW - Alveoli KW - Lung KW - Beryllium KW - Dissolution KW - Minerals KW - Oxides KW - SW 3050:Ultimate disposal of wastes KW - D 04040:Ecosystem and Ecology Studies KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1008845715?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Geochemistry+and+Health&rft.atitle=Release+of+beryllium+from+mineral+ores+in+artificial+lung+and+skin+surface+fluids&rft.au=Duling%2C+Matthew+G%3BStefaniak%2C+Aleksandr+B%3BLawrence%2C+Robert+B%3BChipera%2C+Steve+J%3BAbbas+Virji%2C+M&rft.aulast=Duling&rft.aufirst=Matthew&rft.date=2012-06-01&rft.volume=34&rft.issue=3&rft.spage=313&rft.isbn=&rft.btitle=&rft.title=Environmental+Geochemistry+and+Health&rft.issn=02694042&rft_id=info:doi/10.1007%2Fs10653-011-9421-3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-01 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - Berylliosis; Inhalation; Macrophages; Data processing; Skin; Sweat; Mines; Dust; Alveoli; Ores; Lung; Beryllium; oxides; Dissolution; Diffusion; pH effects; Minerals; Respiratory tract; Beryllium compounds; pH; Exposure; Geochemistry; Hydrogen Ion Concentration; Mice; Linings; Dusts; Oxides DO - http://dx.doi.org/10.1007/s10653-011-9421-3 ER - TY - JOUR T1 - Fatal outbreaks of jaundice in pregnancy and the epidemic history of hepatitis E AN - 1367487835; 18059181 AB - Space-time clustering of people who fall acutely ill with jaundice, then slip into coma and death, is an alarming phenomenon, more markedly so when the victims are mostly or exclusively pregnant. Documentation of the peculiar, fatal predisposition of pregnant women during outbreaks of jaundice identifies hepatitis E and enables construction of its epidemic history. Between the last decade of the 18th century and the early decades of the 20th century, hepatitis E-like outbreaks were reported mainly from Western Europe and several of its colonies. During the latter half of the 20th century, reports of these epidemics, including those that became serologically confirmed as hepatitis E, emanated from, first, the eastern and southern Mediterranean littoral and, thereafter, Southern and Central Asia, Eastern Europe, and the rest of Africa. The dispersal has been accompanied by a trend towards more frequent and larger-scale occurrences. Epidemic and endemic hepatitis E still beset people inhabiting Asia and Africa, especially pregnant women and their fetuses and infants. Their relief necessitates not only accelerated access to potable water and sanitation but also vaccination against hepatitis E. JF - Epidemiology and Infection AU - Teo, C-G AD - Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, GA, USA, CTeo@cdc.gov Y1 - 2012/05// PY - 2012 DA - May 2012 SP - 767 EP - 787 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 140 IS - 5 SN - 0950-2688, 0950-2688 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Colonies KW - Hepatitis KW - ANE, Europe KW - H 12000:Epidemiology and Public Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1367487835?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Fatal+outbreaks+of+jaundice+in+pregnancy+and+the+epidemic+history+of+hepatitis+E&rft.au=Teo%2C+C-G&rft.aulast=Teo&rft.aufirst=C-G&rft.date=2012-05-01&rft.volume=140&rft.issue=5&rft.spage=767&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268811002925 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-06-01 N1 - Number of references - 1 N1 - Last updated - 2014-03-10 N1 - SubjectsTermNotLitGenreText - Hepatitis; ANE, Europe DO - http://dx.doi.org/10.1017/S0950268811002925 ER - TY - JOUR T1 - Sensitization and chronic beryllium disease at a primary manufacturing facility, part 3: exposure-response among short-term workers AN - 1367482333; 16832401 AB - Objectives Exposure-response relations for beryllium sensitization (BeS) and chronic beryllium disease (CBD) using aerosol mass concentration have been inconsistent, although process-related risks found in most studies suggest that exposure-dependent risks exist. We examined exposure-response relations using personal exposure estimates in a beryllium worker cohort with limited work tenure to minimize exposure misclassification. Methods The population comprised workers employed in 1999 with six years or less tenure. Each completed a work history questionnaire and was evaluated for immunological sensitization and CBD. A job-exposure matrix was combined with work histories to create individual estimates of average, cumulative, and highest-job-worked exposure for total, respirable, and submicron beryllium mass concentrations. We obtained odds ratios from logistic regression models for exposure-response relations, and evaluated process-related risks. Results Participation was 90.7% (264/291 eligible). Sensitization prevalence was 9.8% (26/264), with 6 sensitized also diagnosed with CBD (2.3%, 6/264). A general pattern of increasing sensitization prevalence was observed as exposure quartile increased. Both total and respirable beryllium mass concentration estimates were positively associated with sensitization (average and highest job), and CBD (cumulative). Increased sensitization prevalence was identified in metal/oxide production, alloy melting and casting, and maintenance, and for CBD in melting and casting. Lower sensitization prevalence was observed in plant-area administrative work. Conclusions Sensitization was associated with average and highest job exposures, and CBD was associated with cumulative exposure. Both total and respirable mass concentrations were relevant predictors of risk. New process-related risks were identified in melting and casting and maintenance. JF - Scandinavian Journal of Work, Environment & Health AU - Schuler, C R AU - Virji, MA AU - Deubner, D C AU - Stanton, M L AU - Stefaniak, AB AU - Day, G A AU - Park, J Y AU - Kent AU - Sparks, R AU - Kreiss, K AD - Division of Respiratory Disease Studies, Field Studies Branch, NIOSH, Centers for Disease Control and Prevention, 1095 Willowdale Road, MS H2800, Morgantown, WV 26505, USA, cschuler@cdc.gov Y1 - 2012/05// PY - 2012 DA - May 2012 SP - 270 EP - 281 VL - 38 IS - 3 SN - 0355-3140, 0355-3140 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Historical account KW - Metals KW - Manufacturing industry KW - Aerosols KW - Dose-response effects KW - Beryllium KW - Alloys KW - Occupational exposure KW - Maintenance KW - H 1000:Occupational Safety and Health KW - R2 23010:General: Models, forecasting UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1367482333?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Scandinavian+Journal+of+Work%2C+Environment+%26+Health&rft.atitle=Sensitization+and+chronic+beryllium+disease+at+a+primary+manufacturing+facility%2C+part+3%3A+exposure-response+among+short-term+workers&rft.au=Schuler%2C+C+R%3BVirji%2C+MA%3BDeubner%2C+D+C%3BStanton%2C+M+L%3BStefaniak%2C+AB%3BDay%2C+G+A%3BPark%2C+J+Y%3BKent%3BSparks%2C+R%3BKreiss%2C+K&rft.aulast=Schuler&rft.aufirst=C&rft.date=2012-05-01&rft.volume=38&rft.issue=3&rft.spage=270&rft.isbn=&rft.btitle=&rft.title=Scandinavian+Journal+of+Work%2C+Environment+%26+Health&rft.issn=03553140&rft_id=info:doi/10.5271%2Fsjweh.3192 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-06-01 N1 - Last updated - 2013-06-14 N1 - SubjectsTermNotLitGenreText - Manufacturing industry; Metals; Historical account; Aerosols; Dose-response effects; Beryllium; Alloys; Maintenance; Occupational exposure DO - http://dx.doi.org/10.5271/sjweh.3192 ER - TY - JOUR T1 - Sensitization and chronic beryllium disease at a primary manufacturing facility, part 2: validation of historical exposures AN - 1257732495; 16832400 AB - Objective The aim of this study was to evaluate the validity of a job exposure matrix (JEM) constructed for the period 1994-1999. Historical exposure estimates (HEE) for the JEM were constructed for all job and year combinations by applying temporal factors reflecting annual change in area air measurements (1994-1998) to the personal baseline exposure estimates (BEE) collected in 1999. The JEM was generated for an epidemiologic study to examine quantitative exposure-response relationships with sensitization and chronic beryllium disease. Methods The validity of the BEE and HEE was evaluated by comparing them with a validation dataset of independently collected personal beryllium exposure measurements from 1999 and 1994-1998, respectively. Agreement between the JEM and validation data was assessed using relative bias and concordance correlation coefficients (CCC). Results The BEE and HEE overestimated the measured exposures in their respective validation datasets by 8% and 6%, respectively. The CCC reflecting the deviation of the fitted line from the concordance line, showed good agreement for both BEE (CCC=0.80) and HEE (CCC=0.72). Proportional difference did not change with exposure levels or by process area and year. Overall, the agreement between the JEM and validation estimates (from combined HEE and BEE) was high (CCC=0.77). Conclusions This study demonstrated that the reconstructed beryllium exposures at a manufacturing facility were reliable and can be used in epidemiologic studies. JF - Scandinavian Journal of Work, Environment & Health AU - Park, J Y AU - Virji, MA AU - Stefaniak, AB AU - Stanton, M L AU - Day, G A AU - Kent AU - Schuler, C R AU - Kreiss, K AD - NIOSH, Centers for Disease Control and Prevention, Mailstop H-2800, Morgantown, WV 26505, USA, MVirji@cdc.gov Y1 - 2012/05// PY - 2012 DA - May 2012 SP - 259 EP - 269 VL - 38 IS - 3 SN - 0355-3140, 0355-3140 KW - Health & Safety Science Abstracts KW - Historical account KW - Manufacturing industry KW - Dose-response effects KW - Beryllium KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1257732495?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Scandinavian+Journal+of+Work%2C+Environment+%26+Health&rft.atitle=Sensitization+and+chronic+beryllium+disease+at+a+primary+manufacturing+facility%2C+part+2%3A+validation+of+historical+exposures&rft.au=Park%2C+J+Y%3BVirji%2C+MA%3BStefaniak%2C+AB%3BStanton%2C+M+L%3BDay%2C+G+A%3BKent%3BSchuler%2C+C+R%3BKreiss%2C+K&rft.aulast=Park&rft.aufirst=J&rft.date=2012-05-01&rft.volume=38&rft.issue=3&rft.spage=259&rft.isbn=&rft.btitle=&rft.title=Scandinavian+Journal+of+Work%2C+Environment+%26+Health&rft.issn=03553140&rft_id=info:doi/10.5271%2Fsjweh.3187 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-12-01 N1 - Last updated - 2013-06-28 N1 - SubjectsTermNotLitGenreText - Manufacturing industry; Historical account; Dose-response effects; Beryllium DO - http://dx.doi.org/10.5271/sjweh.3187 ER - TY - JOUR T1 - Sensitization and chronic beryllium disease at a primary manufacturing facility, part 1: historical exposure reconstruction AN - 1257732421; 16832399 AB - Objectives Previous epidemiologic studies of beryllium sensitization (BeS) and chronic beryllium disease (CBD) have reported inconsistent exposure-response relationships, likely due to exposure misclassification. The objective of this study was to develop historical estimates of size-selective personal exposure to beryllium for an epidemiologic study. Methods In 1999, a cross-sectional survey of workers hired after 1 January 1994 was conducted at a beryllium production facility. Personal exposure data from two air sampling surveys conducted in 1999 were used to obtain total, respirable, and submicron particle baseline exposure estimates (BEE) for a job-exposure matrix (JEM). General area air samples collected from 1994-1999 were used to estimate annual changes in exposures (temporal factors) for 24 different process areas. Historical exposure estimates (HEE) were calculated by applying the temporal factors to the BEE. Workers were assigned HEE based on their work history, and their historical exposure profile was summarized as cumulative, average, or highest-ever job exposure. Results Changes in exposure over a 6-year period were observed in 10 of the 24 process areas with an overall mean decline of 18% per year. The overall total exposure for study participants over their work tenure ranged from: 0.001-34.44 mu g/m super(3)-year, 0.01-16.26 mu g/m super(3), and 0.01-17.54 mu g/m super(3) for cumulative, average, and highest-ever job, respectively. For respirable exposures, the ranges were: 0.001-15.54 mu g/m super(3)-year, 0.01-3.56 mu g/m super(3), 0.01-5.54 mu g /m super(3) for cumulative, average, and highest-ever job, respectively. Conclusions Using this JEM, exposure-response relationships for BeS and CBD can be explored over a range of exposure metrics such as total, respirable, and submicron beryllium mass concentrations, including summary measures such as cumulative, average, or highest exposures, with the ultimate objective of elucidating a quantitative exposure-response relationship. JF - Scandinavian Journal of Work, Environment & Health AU - Virji, MA AU - Park, J Y AU - Stefaniak, AB AU - Stanton, M L AU - Day, G A AU - Kent AU - Kreiss, K AU - Schuler, C R AD - National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Mailstop H-2800, Morgantown, WV 26505, USA, MVirji@cdc.gov Y1 - 2012/05// PY - 2012 DA - May 2012 SP - 247 EP - 258 VL - 38 IS - 3 SN - 0355-3140, 0355-3140 KW - Health & Safety Science Abstracts KW - Historical account KW - Manufacturing industry KW - Dose-response effects KW - Beryllium KW - Air sampling KW - Particulates KW - Occupational exposure KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1257732421?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Scandinavian+Journal+of+Work%2C+Environment+%26+Health&rft.atitle=Sensitization+and+chronic+beryllium+disease+at+a+primary+manufacturing+facility%2C+part+1%3A+historical+exposure+reconstruction&rft.au=Virji%2C+MA%3BPark%2C+J+Y%3BStefaniak%2C+AB%3BStanton%2C+M+L%3BDay%2C+G+A%3BKent%3BKreiss%2C+K%3BSchuler%2C+C+R&rft.aulast=Virji&rft.aufirst=MA&rft.date=2012-05-01&rft.volume=38&rft.issue=3&rft.spage=247&rft.isbn=&rft.btitle=&rft.title=Scandinavian+Journal+of+Work%2C+Environment+%26+Health&rft.issn=03553140&rft_id=info:doi/10.5271%2Fsjweh.3188 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-12-01 N1 - Last updated - 2013-06-28 N1 - SubjectsTermNotLitGenreText - Manufacturing industry; Historical account; Dose-response effects; Beryllium; Air sampling; Particulates; Occupational exposure DO - http://dx.doi.org/10.5271/sjweh.3188 ER - TY - JOUR T1 - Detection of a Novel Spotted Fever Group Rickettsia in the Gophertortoise Tick AN - 1028021164; 16825672 AB - The gophertortoise tick, Amblyomma tuberculatum (Marx), is distributed throughout the southeastern United States, and its immature life stages have been reported to occasionally bite humans. Here we report detection of a novel spotted fever group (SFG) Rickettsia in A. tuberculatum ticks collected in the southern United States. Among questing ticks collected in Georgia, 10 pools of larvae were identified as gophertortoise ticks, A. tuberculatum. Each of these samples was positive for SFG Rickettsiae. The restriction fragment-length polymorphism profiles were identical to each other, but distinct from those of other rickettsiae previously found in Amblyomma spp. ticks. Partial genetic characterization of the novel agent was achieved by sequencing the 17 kDa, gltA, ompB, ompA, rpoB, and sca4 genes. Analysis of a concatenated tree of four genes (gltA, ompB, ompA, and sca4) demonstrates close relatedness of the detected Rickettsia to several SFG Rickettsia spp. The identical rickettsial DNA was detected in 50 and 70% of adult A. tuberculatum ticks from Mississippi and Florida, respectively. The results indicate wide distribution of a novel Rickettsia, capability for transovarial transmission, and high prevalence in tested tick populations. JF - Journal of Medical Entomology AU - Zemtsova, Galina E AU - Gleim, Elizabeth AU - Yabsley, Michael J AU - Mike Conner, L AU - Mann, Tom AU - Brown, Mary D AU - Wendland, Lori AU - Levin, Michael L AD - Centers for Disease Control and Prevention, Rickettsial Zoonoses Branch, Atlanta, GA 30029., gzemtsova@cdc.gov Y1 - 2012/05// PY - 2012 DA - May 2012 SP - 783 EP - 786 PB - Entomological Society of America, 9301 Annapolis Rd. Lanham MD 20706 United States VL - 49 IS - 3 SN - 0022-2585, 0022-2585 KW - Microbiology Abstracts B: Bacteriology; Entomology Abstracts KW - Bites KW - DNA KW - Developmental stages KW - RpoB protein KW - Spotted fevers KW - Trees KW - Amblyomma KW - Ixodidae KW - Rickettsia UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1028021164?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Medical+Entomology&rft.atitle=Detection+of+a+Novel+Spotted+Fever+Group+Rickettsia+in+the+Gophertortoise+Tick&rft.au=Zemtsova%2C+Galina+E%3BGleim%2C+Elizabeth%3BYabsley%2C+Michael+J%3BMike+Conner%2C+L%3BMann%2C+Tom%3BBrown%2C+Mary+D%3BWendland%2C+Lori%3BLevin%2C+Michael+L&rft.aulast=Zemtsova&rft.aufirst=Galina&rft.date=2012-05-01&rft.volume=49&rft.issue=3&rft.spage=783&rft.isbn=&rft.btitle=&rft.title=Journal+of+Medical+Entomology&rft.issn=00222585&rft_id=info:doi/10.1603%2FME11264 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-07-01 N1 - Number of references - 16 N1 - Last updated - 2012-09-24 N1 - SubjectsTermNotLitGenreText - Spotted fevers; Trees; Bites; DNA; Developmental stages; RpoB protein; Amblyomma; Ixodidae; Rickettsia DO - http://dx.doi.org/10.1603/ME11264 ER - TY - JOUR T1 - Evaluation of integrated registers for tuberculosis and HIV surveillance in children, Ethiopia, 2007-2009 AN - 1024658235; 16832423 AB - In 2008, Ethiopia implemented tuberculosis (TB) treatment registers that included columns for recording human immunodeficiency virus (HIV) test results (integrated registers) to replace the previous system of separate TB and HIV registers (pre-integration registers). We compared the proportion of children with documented HIV rapid test results at eight hospitals before and after adopting the integrated registers. HIV status was more consistently documented in the integrated registers; however, HIV status for infants aged <18 months could not be assessed, as the registers did not capture results from polymerase chain reaction-based testing. Recording procedures should be revised to document age-appropriate HIV diagnostic results and ensure referral for appropriate care. JF - International Journal of Tuberculosis and Lung Disease AU - Click, E S AU - Feleke, B AU - Pevzner, E AU - Fantu, R AU - Gadisa, T AU - Assefa, D AU - Melaku, Z AU - Cain, K AU - Menzies, H AD - Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, 1600 Clifton Rd, MS E-10, Atlanta, GA 30333, USA, eoc9@cdc.gov Y1 - 2012/05// PY - 2012 DA - May 2012 SP - 625 EP - 627 PB - International Union Against Tuberculosis and Lung Disease VL - 16 IS - 5 SN - 1027-3719, 1027-3719 KW - Virology & AIDS Abstracts; Microbiology Abstracts B: Bacteriology KW - Human immunodeficiency virus KW - Mycobacterium KW - Lung diseases KW - Tuberculosis KW - Children KW - Infants KW - Hospitals KW - V 22360:AIDS and HIV KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1024658235?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Evaluation+of+integrated+registers+for+tuberculosis+and+HIV+surveillance+in+children%2C+Ethiopia%2C+2007-2009&rft.au=Click%2C+E+S%3BFeleke%2C+B%3BPevzner%2C+E%3BFantu%2C+R%3BGadisa%2C+T%3BAssefa%2C+D%3BMelaku%2C+Z%3BCain%2C+K%3BMenzies%2C+H&rft.aulast=Click&rft.aufirst=E&rft.date=2012-05-01&rft.volume=16&rft.issue=5&rft.spage=625&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-07-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Lung diseases; Tuberculosis; Children; Hospitals; Infants; Mycobacterium; Human immunodeficiency virus ER - TY - JOUR T1 - Development of a Novel Genus-Specific Real-Time PCR Assay for Detection and Differentiation of Bartonella Species and Genotypes AN - 1024655454; 16765171 AB - The genus Bartonella includes numerous species with varied host associations, including several that infect humans. Development of a molecular diagnostic method capable of detecting the diverse repertoire of Bartonella species while maintaining genus specificity has been a challenge. We developed a novel real-time PCR assay targeting a 301-bp region of the ssrA gene of Bartonella and demonstrated specific amplification in over 30 Bartonella species, subspecies, and strains. Subsequent analysis of ssrA sequences was sufficient to discriminate Bartonella species and provided phylogenetic data consistent with that of gltA, a commonly used gene for differentiating Bartonella genotypes. Using this assay, we identified Bartonella DNA in 29% and 47% of blood specimens from elk in Wyoming and cattle in the Republic of Georgia, respectively. Sequence analysis of a subset of genotypes from elk specimens revealed a cluster most closely related to Bartonella capreoli, and genotypes from cattle were identified as Bartonella bovis, both Bartonella species commonly found in wild and domestic ruminants. Considering the widespread geographic distribution and infectivity potential to a variety of hosts, this assay may be an effective diagnostic method for identification of Bartonella infections in humans and have utility in Bartonella surveillance studies. JF - Journal of Clinical Microbiology AU - Diaz, Maureen H AU - Bai, Ying AU - Malania, Lile AU - Winchell, Jonas M AU - Kosoy, Michael Y AD - Respiratory Diseases Branch, Division of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, MaureenH.Diaz,MDiaz1{at}cdc.gov. Y1 - 2012/05// PY - 2012 DA - May 2012 SP - 1645 EP - 1649 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 50 IS - 5 SN - 0095-1137, 0095-1137 KW - Genetics Abstracts; Microbiology Abstracts B: Bacteriology KW - Phylogeny KW - Ruminantia KW - Geographical distribution KW - Data processing KW - Bartonella KW - Genotypes KW - Infection KW - Blood KW - Differentiation KW - Infectivity KW - Polymerase chain reaction KW - ssrA gene KW - J 02400:Human Diseases KW - G 07730:Development & Cell Cycle UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1024655454?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Development+of+a+Novel+Genus-Specific+Real-Time+PCR+Assay+for+Detection+and+Differentiation+of+Bartonella+Species+and+Genotypes&rft.au=Diaz%2C+Maureen+H%3BBai%2C+Ying%3BMalania%2C+Lile%3BWinchell%2C+Jonas+M%3BKosoy%2C+Michael+Y&rft.aulast=Diaz&rft.aufirst=Maureen&rft.date=2012-05-01&rft.volume=50&rft.issue=5&rft.spage=1645&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.06621-11 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-07-01 N1 - Number of references - 26 N1 - Last updated - 2013-07-15 N1 - SubjectsTermNotLitGenreText - Phylogeny; Differentiation; Blood; Infectivity; Geographical distribution; Data processing; Polymerase chain reaction; Genotypes; Infection; ssrA gene; Ruminantia; Bartonella DO - http://dx.doi.org/10.1128/JCM.06621-11 ER - TY - JOUR T1 - THE FUKUSHIMA RADIOLOGICAL EMERGENCY AND CHALLENGE IDENTIFIED FOR FUTURE PUBLIC HEALTH RESPONSES AN - 1014105560; 16644564 AB - On 11 March 2011, northern Japan was rocked by first a magnitude 9.0 earthquake off the eastern coast and then an ensuing tsunami. The Fukushima Daiichi Nuclear Power Plant complex was hit by these twin disasters, and a cascade of events was initiated that led to radionuclide releases causing widespread radioactive contamination of residential areas, agricultural land, and coastal waters. Radioactive material from Japan was subsequently transmitted to locations around the globe, including the U.S. The levels of radioactive material that arrived in the U.S. were never large enough to be a concern for health effects, but the presence of this material in the environment was enough to create a public health emergency in the U.S. The radiation safety and public health communities in the U.S. are identifying challenges they faced in responding to this incident. This paper discusses three of those challenges: (1) The growing shortage of trained radiation subject matter experts in the field of environmental transport and dosimetry of radio-nuclides; (2) the need to begin expressing all radiation-related quantities in terms of the International System of Units; and (3) the need to define when a radiation dose is or is not one of "public health concern." This list represents only a small subset of the list of challenges being identified by public health agencies that responded to the Fukushima incident. However, these three challenges are fundamental to any radiological emergency response. Addressing them will have a significant positive impact on how the U.S. responds to the next radiological emergency. JF - Health Physics AU - Miller, C W AD - Radiation Studies Branch, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, Mailstop F58, Atlanta, GA 30341, USA, cmiller1@cdc.gov Y1 - 2012/05// PY - 2012 DA - May 2012 SP - 584 EP - 588 PB - Williams & Wilkins, 351 W. Camden St. Baltimore MD 21201 United States VL - 102 IS - 5 SN - 0017-9078, 0017-9078 KW - Pollution Abstracts; Health & Safety Science Abstracts KW - Earthquakes KW - Nuclear power plants KW - USA KW - Agricultural land KW - Emergency preparedness KW - Radioactive materials KW - Dosimetry KW - Seismic activity KW - Residential areas KW - Public health KW - H 2000:Transportation KW - P 1000:MARINE POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1014105560?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+Physics&rft.atitle=THE+FUKUSHIMA+RADIOLOGICAL+EMERGENCY+AND+CHALLENGE+IDENTIFIED+FOR+FUTURE+PUBLIC+HEALTH+RESPONSES&rft.au=Miller%2C+C+W&rft.aulast=Miller&rft.aufirst=C&rft.date=2012-05-01&rft.volume=102&rft.issue=5&rft.spage=584&rft.isbn=&rft.btitle=&rft.title=Health+Physics&rft.issn=00179078&rft_id=info:doi/10.1097%2FHP.0b013e31824d0241 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2013-08-12 N1 - SubjectsTermNotLitGenreText - Earthquakes; Nuclear power plants; Agricultural land; Emergency preparedness; Dosimetry; Radioactive materials; Residential areas; Seismic activity; Public health; USA DO - http://dx.doi.org/10.1097/HP.0b013e31824d0241 ER - TY - JOUR T1 - Residential carbon monoxide alarm prevalence and ordinance awareness. AN - 1012744394; 22473121 AB - Unintentional carbon monoxide (CO) poisoning is a leading cause of poisoning in the United States. Most poisoning cases occur in residential settings and a working CO alarm may prevent many of these events. The use of a CO alarm is mandated in many parts of the country; however, little is known about the compliance and adoption of such ordinances at the population level. This study determined the prevalence of residential CO alarm and awareness of a 2001 CO alarm ordinance in Mecklenburg County, North Carolina in 2009. A random sample of households stratified by housing type (eg, single-family homes, multifamily homes) was included in a cross-sectional survey conducted. One adult respondent from each household was administered a questionnaire that included information on sociodemographic and household characteristics, presence of a CO alarm, and CO alarm ordinance awareness. Data were analyzed using multivariate stratified conditional logistic regression. Among 214 participating households (response rate, 23.4%), 145 (67.8%) reported having a working CO alarm and 79 (36.9%) of the respondents were aware of the CO alarm ordinance. Respondents who were aware of the ordinance had 9 times higher odds (95% confidence interval, 3.3-25.9) of having a CO alarm than those who were unaware. Also, households with an attached garage had more than 2 times higher odds (95% confidence interval, 1.0-6.2) of having a CO alarm than those without an attached garage. Awareness of the CO alarm ordinance was not associated with any sociodemographic (eg, age, sex, race, education, income) or household (eg, home ownership, home construction year) characteristics. Carbon monoxide alarm prevalence in Mecklenburg County households was higher than the national average and was associated with CO alarm ordinance awareness. Public health efforts might benefit from regulations aimed at population-level adoption of preventive health behaviors. JF - Journal of public health management and practice : JPHMP AU - Iqbal, Shahed AU - Clower, Jacquelyn H AU - Saha, Shubhayu AU - Boehmer, Tegan K AU - Mattson, Christine AU - Yip, Fuyuen Y AU - Cobb, Robert D AU - Flanders, W D AD - Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA. SIqbal@cdc.gov PY - 2012 SP - 272 EP - 278 VL - 18 IS - 3 KW - Carbon Monoxide KW - 7U1EE4V452 KW - Health technology assessment KW - Young Adult KW - Housing KW - Humans KW - Aged KW - Cross-Sectional Studies KW - Aged, 80 and over KW - Adult KW - North Carolina KW - Data Collection KW - Middle Aged KW - Carbon Monoxide Poisoning -- prevention & control KW - Female KW - Male KW - Air Pollution, Indoor -- analysis KW - Carbon Monoxide -- analysis KW - Guideline Adherence KW - Environmental Monitoring -- instrumentation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1012744394?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+public+health+management+and+practice+%3A+JPHMP&rft.atitle=Residential+carbon+monoxide+alarm+prevalence+and+ordinance+awareness.&rft.au=Iqbal%2C+Shahed%3BClower%2C+Jacquelyn+H%3BSaha%2C+Shubhayu%3BBoehmer%2C+Tegan+K%3BMattson%2C+Christine%3BYip%2C+Fuyuen+Y%3BCobb%2C+Robert+D%3BFlanders%2C+W+D&rft.aulast=Iqbal&rft.aufirst=Shahed&rft.date=2012-05-01&rft.volume=18&rft.issue=3&rft.spage=272&rft.isbn=&rft.btitle=&rft.title=Journal+of+public+health+management+and+practice+%3A+JPHMP&rft.issn=1550-5022&rft_id=info:doi/10.1097%2FPHH.0b013e318221b1d1 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-06-04 N1 - Date created - 2012-04-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1097/PHH.0b013e318221b1d1 ER - TY - JOUR T1 - Pneumococcal antigen testing of blood culture broth to enhance the detection of Streptococcus pneumoniae bacteremia AN - 1011209208; 16540800 AB - The purpose of this investigation was to enhance the detection of pneumococcal bacteremia cases using the Binax NOW registered immunochromatographic test (ICT) on blood culture broth as part of surveillance in two rural Thailand provinces. Blood cultures were collected as clinically indicated from hospitalized patients. ICT was performed on broth from culture bottles flagged as positive by BactT/ALERT registered (alarm-positive) but which failed to grow organisms on subculture. During the period May 2005-June 2007, ICT was positive on 43 (24%) of 182 alarm-positive blood cultures with no growth on subculture. Compared to pneumococcal bacteremia cases confirmed by culture, cases detected only by ICT had a longer median time from culture collection to incubation and a longer median time from alarm positivity to subculture, and were more likely to be from patients pretreated with antibiotics. In a subsequent surveillance period (July 2007-December 2009), ICT continued to detect additional pneumococcal cases, but in a lower proportion of samples (7 of 221, 3.2%). Recently, as part of a separate study, ICT applied to uninoculated blood culture broth produced weak-positive results, mandating caution if testing broth from patient blood cultures. The antigen testing of blood culture broth appears to enhance the detection of pneumococcal bacteremia, but a controlled evaluation is needed. JF - European Journal of Clinical Microbiology & Infectious Diseases AU - Baggett, H C AU - Rhodes, J AU - Dejsirilert, S AU - Salika, P AU - Wansom, T AU - Jorakate, P AU - Kaewpan, A AU - Olsen, S J AU - Maloney, SA AU - Peruski, L F AD - International Emerging Infections Program, Thailand Ministry of Public Health (MOPH) - U.S. Centers for Disease Control and Prevention (CDC) Collaboration, Nonthaburi, Thailand, kipb@th.cdc.gov Y1 - 2012/05// PY - 2012 DA - May 2012 SP - 753 EP - 756 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 31 IS - 5 SN - 0934-9723, 0934-9723 KW - Microbiology Abstracts B: Bacteriology KW - Antibiotics KW - Bacteremia KW - Blood culture KW - Culture collections KW - Subculture KW - Streptococcus pneumoniae KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1011209208?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=European+Journal+of+Clinical+Microbiology+%26+Infectious+Diseases&rft.atitle=Pneumococcal+antigen+testing+of+blood+culture+broth+to+enhance+the+detection+of+Streptococcus+pneumoniae+bacteremia&rft.au=Baggett%2C+H+C%3BRhodes%2C+J%3BDejsirilert%2C+S%3BSalika%2C+P%3BWansom%2C+T%3BJorakate%2C+P%3BKaewpan%2C+A%3BOlsen%2C+S+J%3BMaloney%2C+SA%3BPeruski%2C+L+F&rft.aulast=Baggett&rft.aufirst=H&rft.date=2012-05-01&rft.volume=31&rft.issue=5&rft.spage=753&rft.isbn=&rft.btitle=&rft.title=European+Journal+of+Clinical+Microbiology+%26+Infectious+Diseases&rft.issn=09349723&rft_id=info:doi/10.1007%2Fs10096-011-1370-3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2012-05-18 N1 - SubjectsTermNotLitGenreText - Blood culture; Culture collections; Subculture; Bacteremia; Antibiotics; Streptococcus pneumoniae DO - http://dx.doi.org/10.1007/s10096-011-1370-3 ER - TY - JOUR T1 - Cadmium and lung cancer mortality accounting for simultaneous arsenic exposure. AN - 1001961982; 22271639 AB - Prior investigations identified an association between airborne cadmium and lung cancer but questions remain regarding confounding by arsenic, a well-established lung carcinogen. A cadmium smelter population exhibiting excess lung cancer was re-analysed using a retrospective exposure assessment for arsenic (As), updated mortality (1940-2002), a revised cadmium (Cd) exposure matrix and improved work history information. Cumulative exposure metrics for both cadmium and arsenic were strongly associated making estimation of their independent effects difficult. Standardised mortality ratios (SMRs) were modelled with Poisson regression with the contribution of arsenic to lung cancer risk constrained by exposure-response estimates previously reported. The results demonstrate (1) a statistically significant effect of Cd independent of As (SMR=3.2 for 10 mg-year/m(3) Cd, p=0.012), (2) a substantial healthy worker effect for lung cancer (for unexposed workers, SMR=0.69) and (3) a large deficit in lung cancer mortality among Hispanic workers (SMR=0.27, p=0.009), known to have low lung cancer rates. A supralinear dose-rate effect was observed (contribution to risk with increasing exposure intensity has declining positive slope). Lung cancer mortality was somewhat better predicted using a cadmium burden metric with a half-life of about 20-25 years. These findings support an independent effect for cadmium in risk of lung cancer mortality. 1/1000 excess lifetime risk of lung cancer death is predicted from an airborne exposure of about 2.4 μg/m(3) Cd. JF - Occupational and environmental medicine AU - Park, Robert M AU - Stayner, Leslie T AU - Petersen, Martin R AU - Finley-Couch, Melissa AU - Hornung, Richard AU - Rice, Carol AD - National Institute for Occupational Safety and Health, Education and Information Division, Cincinnati, OH 45226, USA. rhp9@cdc.gov Y1 - 2012/05// PY - 2012 DA - May 2012 SP - 303 EP - 309 VL - 69 IS - 5 KW - Carcinogens, Environmental KW - 0 KW - Cadmium KW - 00BH33GNGH KW - Arsenic KW - N712M78A8G KW - Index Medicus KW - Young Adult KW - Regression Analysis KW - Humans KW - Adult KW - Retrospective Studies KW - Middle Aged KW - United States -- epidemiology KW - Male KW - Arsenic -- toxicity KW - Cadmium -- toxicity KW - Occupational Exposure -- adverse effects KW - Lung Neoplasms -- mortality KW - Lung Neoplasms -- chemically induced KW - Carcinogens, Environmental -- toxicity KW - Occupational Diseases -- chemically induced KW - Occupational Diseases -- mortality UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1001961982?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Occupational+and+environmental+medicine&rft.atitle=Cadmium+and+lung+cancer+mortality+accounting+for+simultaneous+arsenic+exposure.&rft.au=Park%2C+Robert+M%3BStayner%2C+Leslie+T%3BPetersen%2C+Martin+R%3BFinley-Couch%2C+Melissa%3BHornung%2C+Richard%3BRice%2C+Carol&rft.aulast=Park&rft.aufirst=Robert&rft.date=2012-05-01&rft.volume=69&rft.issue=5&rft.spage=303&rft.isbn=&rft.btitle=&rft.title=Occupational+and+environmental+medicine&rft.issn=1470-7926&rft_id=info:doi/10.1136%2Foemed-2011-100149 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-05-29 N1 - Date created - 2012-04-16 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1136/oemed-2011-100149 ER - TY - JOUR T1 - Associations between radiographic findings and spirometry in a community exposed to Libby amphibole. AN - 1001955434; 22383589 AB - Among asbestos-exposed individuals, abnormal spirometry is usually associated with parenchymal abnormalities or diffuse pleural thickening. Localised pleural thickening (LPT), the most common abnormality associated with asbestos exposure, is typically thought to be a marker of exposure with little clinical consequence. Our objective was to determine if abnormal spirometry is associated with LPT independent of other abnormalities, using data from community-based screening conducted in Libby, Montana. Subjects were a subset of screening participants comprising persons with interpretable spirometry and chest radiograph results (n=6475). Chest radiographs were independently evaluated by two or three B readers, and participants were classified by mutually exclusive categories of spirometry outcome: normal, restriction, obstruction or mixed defect. Restrictive spirometry was strongly associated with parenchymal abnormalities (OR 2.9; 95% CI 1.4 to 6.0) and diffuse pleural thickening (OR 4.1; 95% CI 2.1 to 7.8). Controlling for the presence of these abnormalities as well as age, smoking status and other covariates, restrictive spirometry was also associated with LPT (OR 1.4; 95% CI 1.1 to 1.8). The risk of restrictive spirometric findings correlated with the severity of LPT. In this large community-based screening cohort, restrictive spirometry is significantly associated with LPT, indicating that this abnormality may result in lung function impairment. Physicians treating patients exposed to Libby amphibole should be aware that LPT may have functional consequences. JF - Occupational and environmental medicine AU - Larson, Theodore C AU - Lewin, Michael AU - Gottschall, E Brigitte AU - Antao, Vinicius C AU - Kapil, Vikas AU - Rose, Cecile S AD - Division of Health Studies, Agency for Toxic Substances and Disease Registry, Atlanta, GA 30341, USA. thl3@cdc.gov Y1 - 2012/05// PY - 2012 DA - May 2012 SP - 361 EP - 366 VL - 69 IS - 5 KW - Asbestos, Amphibole KW - 0 KW - Index Medicus KW - Young Adult KW - Logistic Models KW - Humans KW - Cohort Studies KW - Adult KW - Predictive Value of Tests KW - Middle Aged KW - Radiography KW - Adolescent KW - Male KW - Female KW - Asbestos, Amphibole -- toxicity KW - Spirometry KW - Pleural Diseases -- etiology KW - Asbestosis -- physiopathology KW - Pleural Diseases -- physiopathology KW - Pleural Diseases -- diagnostic imaging KW - Asbestosis -- diagnostic imaging UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1001955434?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Occupational+and+environmental+medicine&rft.atitle=Associations+between+radiographic+findings+and+spirometry+in+a+community+exposed+to+Libby+amphibole.&rft.au=Larson%2C+Theodore+C%3BLewin%2C+Michael%3BGottschall%2C+E+Brigitte%3BAntao%2C+Vinicius+C%3BKapil%2C+Vikas%3BRose%2C+Cecile+S&rft.aulast=Larson&rft.aufirst=Theodore&rft.date=2012-05-01&rft.volume=69&rft.issue=5&rft.spage=361&rft.isbn=&rft.btitle=&rft.title=Occupational+and+environmental+medicine&rft.issn=1470-7926&rft_id=info:doi/10.1136%2Foemed-2011-100316 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-05-29 N1 - Date created - 2012-04-16 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1136/oemed-2011-100316 ER - TY - JOUR T1 - Focused actions to protect carbon nanotube workers. AN - 1000407749; 22392774 AB - There is still uncertainty about the potential health hazards of carbon nanotubes (CNTs) particularly involving carcinogenicity. However, the evidence is growing that some types of CNTs and nanofibers may have carcinogenic properties. The critical question is that while the carcinogenic potential of CNTs is being further investigated, what steps should be taken to protect workers who face exposure to CNTs, current and future, if CNTs are ultimately found to be carcinogenic? This paper addresses five areas to help focus action to protect workers: (i) review of the current evidence on the carcinogenic potential of CNTs; (ii) role of physical and chemical properties related to cancer development; (iii) CNT doses associated with genotoxicity in vitro and in vivo; (iv) workplace exposures to CNT; and (v) specific risk management actions needed to protect workers. Copyright © 2012 Wiley Periodicals, Inc. This article is a U.S. Government work and is in the public domain in the USA. JF - American journal of industrial medicine AU - Schulte, Paul A AU - Kuempel, Eileen D AU - Zumwalde, Ralph D AU - Geraci, Charles L AU - Schubauer-Berigan, Mary K AU - Castranova, Vincent AU - Hodson, Laura AU - Murashov, Vladimir AU - Dahm, Matthew M AU - Ellenbecker, Michael AD - National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, Ohio, USA. pschulte@cdc.gov Y1 - 2012/05// PY - 2012 DA - May 2012 SP - 395 EP - 411 VL - 55 IS - 5 KW - Nanotubes, Carbon KW - 0 KW - Index Medicus KW - Animals KW - Humans KW - Risk Management KW - Occupational Exposure -- prevention & control KW - Nanotubes, Carbon -- chemistry KW - Inhalation Exposure -- prevention & control KW - DNA Damage KW - Pulmonary Fibrosis -- chemically induced KW - Lung -- drug effects KW - Occupational Exposure -- adverse effects KW - Lung -- pathology KW - Nanotubes, Carbon -- toxicity KW - Neoplasms -- etiology KW - Inhalation Exposure -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1000407749?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+journal+of+industrial+medicine&rft.atitle=Focused+actions+to+protect+carbon+nanotube+workers.&rft.au=Schulte%2C+Paul+A%3BKuempel%2C+Eileen+D%3BZumwalde%2C+Ralph+D%3BGeraci%2C+Charles+L%3BSchubauer-Berigan%2C+Mary+K%3BCastranova%2C+Vincent%3BHodson%2C+Laura%3BMurashov%2C+Vladimir%3BDahm%2C+Matthew+M%3BEllenbecker%2C+Michael&rft.aulast=Schulte&rft.aufirst=Paul&rft.date=2012-05-01&rft.volume=55&rft.issue=5&rft.spage=395&rft.isbn=&rft.btitle=&rft.title=American+journal+of+industrial+medicine&rft.issn=1097-0274&rft_id=info:doi/10.1002%2Fajim.22028 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-07-31 N1 - Date created - 2012-04-13 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1002/ajim.22028 ER - TY - CPAPER T1 - Making breastfeeding a public health priority in the United States and new tools to measure progress T2 - Experimental Biology 2012 (EB 2012) AN - 1313041663; 6160119 JF - Experimental Biology 2012 (EB 2012) AU - Grummer-Strawn, L Y1 - 2012/04/21/ PY - 2012 DA - 2012 Apr 21 KW - USA KW - Public health KW - Breast feeding UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313041663?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Experimental+Biology+2012+%28EB+2012%29&rft.atitle=Making+breastfeeding+a+public+health+priority+in+the+United+States+and+new+tools+to+measure+progress&rft.au=Grummer-Strawn%2C+L&rft.aulast=Grummer-Strawn&rft.aufirst=L&rft.date=2012-04-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Experimental+Biology+2012+%28EB+2012%29&rft.issn=&rft_id=info:doi/ L2 - http://experimentalbiology.org/eb/pages/upload/file/pdfs/Final%20Print.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Implementing and evaluating the Health and Human Services and General Services Administration's Health and Sustainability Guidelines for federal concessions and vending operations T2 - Experimental Biology 2012 (EB 2012) AN - 1313034234; 6160200 JF - Experimental Biology 2012 (EB 2012) AU - Kimmons, J Y1 - 2012/04/21/ PY - 2012 DA - 2012 Apr 21 KW - Guidelines KW - Sustainability KW - Public health KW - Concessions KW - Resource management UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313034234?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Experimental+Biology+2012+%28EB+2012%29&rft.atitle=Implementing+and+evaluating+the+Health+and+Human+Services+and+General+Services+Administration%27s+Health+and+Sustainability+Guidelines+for+federal+concessions+and+vending+operations&rft.au=Kimmons%2C+J&rft.aulast=Kimmons&rft.aufirst=J&rft.date=2012-04-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Experimental+Biology+2012+%28EB+2012%29&rft.issn=&rft_id=info:doi/ L2 - http://experimentalbiology.org/eb/pages/upload/file/pdfs/Final%20Print.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Overview of obesity epidemic in the U.S. T2 - Experimental Biology 2012 (EB 2012) AN - 1313034093; 6160196 JF - Experimental Biology 2012 (EB 2012) AU - Dietz, W Y1 - 2012/04/21/ PY - 2012 DA - 2012 Apr 21 KW - USA KW - Obesity KW - Reviews KW - Epidemics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313034093?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Experimental+Biology+2012+%28EB+2012%29&rft.atitle=Overview+of+obesity+epidemic+in+the+U.S.&rft.au=Dietz%2C+W&rft.aulast=Dietz&rft.aufirst=W&rft.date=2012-04-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Experimental+Biology+2012+%28EB+2012%29&rft.issn=&rft_id=info:doi/ L2 - http://experimentalbiology.org/eb/pages/upload/file/pdfs/Final%20Print.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - JOUR T1 - Semi-quantitative analysis of influenza samples using the Luminex xTAG registered respiratory viral panel kit AN - 954662530; 16423712 AB - The Luminex xTAG registered respiratory viral panel (RVP) kit simultaneously detects and identifies multiple respiratory viruses including several subtypes of influenza A using a multiplex nucleic acid amplification test assay platform. The emitted fluorescence signal from the RVP assay provides qualitative information on the presence of a particular viral species in respiratory specimens. However, a quantitative assessment is preferred when monitoring environmental samples for respiratory viruses. In this study, we explored the potential use of the RVP kit as a semi-quantitative screening assay for influenza virus detection. The concentration- response of the RVP assay was modeled using four-parameter logistic (4-PL) fits of mean fluorescence intensity (MFI) versus dilute ranges of the influenza A matrix gene, seasonal influenza vaccine, and 2009 H1N1 influenza vaccine. The goodness of fit of the 4-PL model was evaluated by comparing the copy number determined with the fitted model (observed copy number) with the copy number calculated from the dilution of the matrix DNA or vaccine (expected copy number). For the matrix DNA and 2009 H1N1 vaccine, the 4-PL model provided good fit for the influenza A RVP assay response over factors of 10 super(3) to 10 super(4). For seasonal influenza vaccine, the model provided good fit for RVP assay response to influenza A, influenza B, H1, and H3. JF - Toxicology Mechanisms and Methods AU - Smith, J AU - Sammons, D AU - Toennis, C AU - Butler, MA AU - Blachere, F AU - Beezhold, D AD - Biomonitoring Research Team, Biomonitoring and Health Assessment Branch, National Institute for Occupational Safety and Health, Cincinnati, Ohio, USA, jps3@cdc.gov Y1 - 2012/04// PY - 2012 DA - Apr 2012 SP - 211 EP - 217 VL - 22 IS - 3 SN - 1537-6516, 1537-6516 KW - Virology & AIDS Abstracts; Environment Abstracts; Toxicology Abstracts KW - Influenza B KW - vaccines KW - Influenza A KW - Viruses KW - influenza KW - Models KW - Sulfur dioxide KW - DNA vaccines KW - Seasonal variations KW - Environmental monitoring KW - Fluorescence KW - copy number KW - Influenza virus KW - nucleic acids KW - DNA KW - Vaccines KW - Nucleic acids KW - X 24310:Pharmaceuticals KW - V 22310:Genetics, Taxonomy & Structure KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/954662530?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+Mechanisms+and+Methods&rft.atitle=Semi-quantitative+analysis+of+influenza+samples+using+the+Luminex+xTAG+registered+respiratory+viral+panel+kit&rft.au=Smith%2C+J%3BSammons%2C+D%3BToennis%2C+C%3BButler%2C+MA%3BBlachere%2C+F%3BBeezhold%2C+D&rft.aulast=Smith&rft.aufirst=J&rft.date=2012-04-01&rft.volume=22&rft.issue=3&rft.spage=211&rft.isbn=&rft.btitle=&rft.title=Toxicology+Mechanisms+and+Methods&rft.issn=15376516&rft_id=info:doi/10.3109%2F15376516.2011.610387 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2012-04-06 N1 - SubjectsTermNotLitGenreText - Influenza B; nucleic acids; Fluorescence; DNA vaccines; Influenza A; Vaccines; Models; copy number; Environmental monitoring; vaccines; Sulfur dioxide; Viruses; DNA; Seasonal variations; Nucleic acids; influenza; Influenza virus DO - http://dx.doi.org/10.3109/15376516.2011.610387 ER - TY - JOUR T1 - Impact of Air Velocity on the Detection of Fires in Conveyor Belt Haulageways AN - 926882776; 16370769 AB - A series of large-scale experiments were conducted in an above-ground fire gallery using three different types of fire-resistant conveyor belts and four air velocities for each belt. The goal of the experiments was to understand and quantify the effects of air velocity on the detection of fires in underground conveyor belt haulageways and to determine the rates of generation of toxic gases and smoke as a fire progresses through the stages of smoldering coal, flaming coal, and finally a flaming conveyor belt. In the experiments, electrical strip heaters, imbedded approximately 5 cm below the top surface of a large mass of coal rubble, were used to ignite the coal, producing an open flame. The flaming coal mass subsequently ignited 1.83-m-wide conveyor belts located approximately 0.30 m above the coal surface. Gas samples were drawn through an averaging probe for continuous measurement of CO, CO sub(2), and O sub(2) as the fire progressed. Approximately 20 m from the fire origin and 0.5 m below the roof of the gallery, two commercially available smoke detectors, a light obscuration meter, and a sampling probe for measurement of total mass concentration of smoke particles were placed. Two video cameras were located upstream of the fire origin and along the gallery at about 14 m and 5 m in order to detect both smoke and flames from the fire. This paper discusses the impact of ventilation airflow on alarm times of the smoke detectors and video cameras, CO levels, smoke optical densities and smoke obscuration, total smoke mass concentrations, and fire heat release rates, examining how these various parameters depend upon air velocity and air quantity, the product of air velocity, and entry cross-section. JF - Fire Technology AU - Perera, Inoka Eranda AU - Litton, Charles D AD - Pittsburgh Research Laboratory, National Institute for Occupational Safety and Health, PO Box 18070, 626 Cochrans Mill Road, Pittsburgh, PA, 15236, USA, EPerera@cdc.gov Y1 - 2012/04// PY - 2012 DA - Apr 2012 SP - 405 EP - 418 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 48 IS - 2 SN - 0015-2684, 0015-2684 KW - Health & Safety Science Abstracts KW - Smoke KW - Fires KW - galleries KW - upstream KW - Gases KW - Ventilation KW - Velocity KW - Coal KW - Carbon dioxide KW - H 7000:Fire Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/926882776?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Fire+Technology&rft.atitle=Impact+of+Air+Velocity+on+the+Detection+of+Fires+in+Conveyor+Belt+Haulageways&rft.au=Perera%2C+Inoka+Eranda%3BLitton%2C+Charles+D&rft.aulast=Perera&rft.aufirst=Inoka&rft.date=2012-04-01&rft.volume=48&rft.issue=2&rft.spage=405&rft.isbn=&rft.btitle=&rft.title=Fire+Technology&rft.issn=00152684&rft_id=info:doi/10.1007%2Fs10694-011-0228-7 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Smoke; galleries; Fires; upstream; Gases; Ventilation; Velocity; Coal; Carbon dioxide DO - http://dx.doi.org/10.1007/s10694-011-0228-7 ER - TY - JOUR T1 - Fatal Rocky Mountain Spotted Fever in the United States, 1999-2007 AN - 1113227973; 17172222 AB - Death from Rocky Mountain spotted fever (RMSF) is preventable with prompt, appropriate treatment. Data from two independent sources were analyzed to estimate the burden of fatal RMSF and identify risk factors for fatal RMSF in the United States during 1999-2007. Despite increased reporting of RMSF cases to the Centers for Disease Control and Prevention, no significant changes in the estimated number of annual fatal RMSF cases were found. American Indians were at higher risk of fatal RMSF relative to whites (relative risk [RR] = 3.9), and children 5-9 years of age (RR = 6.0) and adults greater than or equal to 70 years of age (RR = 3.0) were also at increased risk relative to other ages. Persons with cases of RMSF with an immunosuppressive condition were at increased risk of death (RR = 4.4). Delaying treatment of RMSF was also associated with increased deaths. These results may indicate a gap between recommendations and practice. JF - American Journal of Tropical Medicine and Hygiene AU - Dahlgren, F S AU - Holman, R C AU - Paddock, C D AU - Callinan, L S AU - McQuiston, J H AD - Centers for Disease Control and Prevention, 1600 Clifton Road NE, Mailstop A30, Atlanta, CA 30333, USA, iot0@cdc.gov Y1 - 2012/04// PY - 2012 DA - April 2012 SP - 713 EP - 719 VL - 86 IS - 4 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Risk Abstracts; Health & Safety Science Abstracts KW - Mortality KW - Age KW - Data processing KW - Disease control KW - Children KW - North America, Rocky Mts. KW - Mountains KW - Rocky Mountain spotted fever KW - USA KW - Prevention KW - Risk factors KW - Ethnic groups KW - K 03400:Human Diseases KW - J 02400:Human Diseases KW - H 0500:General KW - R2 23010:General: Models, forecasting UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1113227973?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Fatal+Rocky+Mountain+Spotted+Fever+in+the+United+States%2C+1999-2007&rft.au=Dahlgren%2C+F+S%3BHolman%2C+R+C%3BPaddock%2C+C+D%3BCallinan%2C+L+S%3BMcQuiston%2C+J+H&rft.aulast=Dahlgren&rft.aufirst=F&rft.date=2012-04-01&rft.volume=86&rft.issue=4&rft.spage=713&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.2012.11-0453 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-10-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Rocky Mountain spotted fever; Age; Data processing; Risk factors; Disease control; Children; Mountains; Mortality; Prevention; Ethnic groups; North America, Rocky Mts.; USA DO - http://dx.doi.org/10.4269/ajtmh.2012.11-0453 ER - TY - JOUR T1 - Medication-Related Barriers to Entering HIV Care AN - 1014105411; 16644441 AB - Early entry to HIV care and receipt of antiretroviral therapy improve the health of the individual and decrease the risk of transmission in the community. To increase the limited information on prospective decisions to enter care and how these decisions relate to beliefs about HIV medications, we analyzed interview data from the Never in Care Project, a multisite project conducted in Indiana, New Jersey, New York City, Philadelphia, and Washington State. From March 2008 through August 2010, we completed structured interviews with 134 persons with no evidence of HIV care entry, 48 of whom also completed qualitative interviews. Many respondents believed that HIV care entails the passive receipt of medications that may be harmful or unnecessary, resulting in reluctance to enter care. Respondents voiced concerns about prescription practices and preserving future treatment options, mistrust of medications and medical care providers, and ambivalence about the life-preserving properties of medications in light of an assumed negative impact on quality of life. Our results support the provision of information on other benefits of care (beyond medications), elicitation of concerns about medications, and assessment of psychosocial barriers to entering care. These tasks should begin at the time a positive test result is delivered and continue throughout the linkage-to-care process; for persons unwilling to enter care immediately, support should be provided in nonmedical settings. JF - AIDS Patient Care and STDs AU - Beer, L AU - Fagan, J L AU - Garland, P AU - Valverde, EE AU - Bolden, B AU - Brady, KA AU - Courogen, M AU - Hillman, D AU - Neaigus, A AU - Bertolli, J AD - Centers for Disease Control and Prevention, 1600 Clifton Road, NE, MS E-46, Atlanta, GA 30333, USA, lbeer@cdc.gov Y1 - 2012/04// PY - 2012 DA - Apr 2012 SP - 214 EP - 221 VL - 26 IS - 4 SN - 1087-2914, 1087-2914 KW - Risk Abstracts; Virology & AIDS Abstracts KW - Acquired immune deficiency syndrome KW - Data processing KW - USA, New Jersey KW - USA, Pennsylvania, Philadelphia KW - antiretroviral therapy KW - Risk reduction KW - USA, Indiana KW - USA, Washington KW - USA, New York, New York City KW - Human immunodeficiency virus KW - antiretroviral agents KW - quality of life KW - Drugs KW - Sexually transmitted diseases KW - Urban areas KW - Quality of life KW - V 22360:AIDS and HIV KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1014105411?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+Patient+Care+and+STDs&rft.atitle=Medication-Related+Barriers+to+Entering+HIV+Care&rft.au=Beer%2C+L%3BFagan%2C+J+L%3BGarland%2C+P%3BValverde%2C+EE%3BBolden%2C+B%3BBrady%2C+KA%3BCourogen%2C+M%3BHillman%2C+D%3BNeaigus%2C+A%3BBertolli%2C+J&rft.aulast=Beer&rft.aufirst=L&rft.date=2012-04-01&rft.volume=26&rft.issue=4&rft.spage=214&rft.isbn=&rft.btitle=&rft.title=AIDS+Patient+Care+and+STDs&rft.issn=10872914&rft_id=info:doi/10.1089%2Fapc.2011.0407 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Data processing; antiretroviral therapy; Quality of life; Acquired immune deficiency syndrome; Human immunodeficiency virus; antiretroviral agents; Risk reduction; quality of life; Drugs; Sexually transmitted diseases; Urban areas; USA, Indiana; USA, Washington; USA, New York, New York City; USA, Pennsylvania, Philadelphia; USA, New Jersey DO - http://dx.doi.org/10.1089/apc.2011.0407 ER - TY - JOUR T1 - Effect of HIV infection on tolerability and bacteriologic outcomes of tuberculosis treatment AN - 1011216564; 16564183 AB - SETTING: Two international, multicenter Phase 2 clinical trials examining fluoroquinolone-containing regimens in adults with smear-positive pulmonary tuberculosis (TB), conducted from July 2003 to March 2007. Both trials enrolled human immunodeficiency virus (HIV) infected participants who were not receiving antiretroviral therapy (ART) at TB treatment initiation. OBJECTIVE: To assess the impact of HIV infection on TB treatment outcomes in Phase 2 clinical trials. DESIGN: Cross-protocol analysis comparing the safety, tolerability and outcomes of anti-tuberculosis treatment by HIV status. RESULTS: Of 750 participants who received at least one dose of study treatment, 123 (16%) were HIV-infected. Treatment completion rates were similar by HIV status (81% infected vs. 85% non-infected), as were rates of week 8 culture conversion (66% infected vs. 63% non-infected), and treatment failure (5% infected vs. 3% non-infected). Among HIV-infected participants, treatment failure detected using liquid media was more frequent in those treated thrice weekly (14% thrice weekly vs. 2% daily, P = 0.03). HIV-infected participants more frequently experienced an adverse event during the intensive phase treatment than non-HIV-infected participants (30% vs. 15%, P < 0.01). CONCLUSION: HIV-infected persons not receiving ART had more adverse events during the intensive phase of anti-tuberculosis treatment, but tolerated treatment well. Failure rates were higher among HIV-infected persons treated with thrice-weekly intensive phase therapy. JF - International Journal of Tuberculosis and Lung Disease AU - Bliven-Sizemore, EE AU - Johnson, J L AU - Goldberg, S AU - Burman, W J AU - Villarino, ME AU - Chaisson, R E AD - Division of Tuberculosis Elimination, Centers for Disease Control and Prevention/Clinical Research Branch, 1600 Clifton Road NE, MS E-10, Atlanta, GA 30333, USA, ebliven@cdc.gov Y1 - 2012/04// PY - 2012 DA - Apr 2012 SP - 473 EP - 479 PB - International Union Against Tuberculosis and Lung Disease VL - 16 IS - 4 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Virology & AIDS Abstracts; Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts KW - Bacteria KW - Mycobacterium KW - antiretroviral therapy KW - Lung diseases KW - clinical trials KW - Infection KW - Clinical trials KW - tuberculosis KW - Safety engineering KW - Human immunodeficiency virus KW - Lung KW - antiretroviral agents KW - infection KW - Tuberculosis KW - Side effects KW - Media (culture) KW - A 01340:Antibiotics & Antimicrobials KW - V 22360:AIDS and HIV KW - J 02400:Human Diseases KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1011216564?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Effect+of+HIV+infection+on+tolerability+and+bacteriologic+outcomes+of+tuberculosis+treatment&rft.au=Bliven-Sizemore%2C+EE%3BJohnson%2C+J+L%3BGoldberg%2C+S%3BBurman%2C+W+J%3BVillarino%2C+ME%3BChaisson%2C+R+E&rft.aulast=Bliven-Sizemore&rft.aufirst=EE&rft.date=2012-04-01&rft.volume=16&rft.issue=4&rft.spage=473&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - antiretroviral therapy; Lung diseases; Tuberculosis; Infection; Clinical trials; Media (culture); tuberculosis; Safety engineering; Lung; Human immunodeficiency virus; antiretroviral agents; infection; clinical trials; Side effects; Bacteria; Mycobacterium ER - TY - JOUR T1 - Occupational exposure to diisononyl phthalate (DiNP) in polyvinyl chloride processing operations AN - 1008841069; 16453429 AB - Purpose: Diisononyl phthalate (DiNP) is primarily used as a plasticizer in polyvinyl chloride (PVC) materials. While information is available on general population exposure to DiNP, occupational exposure data are lacking. We present DiNP metabolite urinary concentrations in PVC processing workers, estimate DiNP daily intake for these workers, and compare worker estimates to other populations. Methods: We assessed DiNP exposure in participants from two companies that manufactured PVC materials, a PVC film manufacturer (n = 25) and a PVC custom compounder (n = 12). A mid-shift and end-shift urine sample was collected from each participant and analyzed for the DiNP metabolite mono(carboxy-isooctyl) phthalate (MCiOP). Mixed models were used to assess the effect on MCiOP concentrations of a worker being assigned to (1) a task using DiNP and (2) a shift where DiNP was used. A simple pharmacokinetic model was used to estimate DiNP daily intake from the MCiOP concentrations. Results: Creatinine-adjusted MCiOP urinary concentrations ranged from 0.42-80 mu g/g in PVC film and from 1.11-13.4 mu g/g in PVC compounding. PVC film participants who worked on a task using DiNP (n = 7) had the highest MCiOP geometric mean (GM) end-shift concentration (25.2 mu g/g), followed by participants who worked on a shift where DiNP was used (n = 11) (17.7 mu g/g) as compared to participants with no task (2.92 mu g/g) or shift (2.08 mu g/g) exposure to DiNP. The GM end-shift MCiOP concentration in PVC compounding participants (4.80 mu g/g) was comparable to PVC film participants with no task or shift exposure to DiNP. Because no PVC compounding participants were assigned to tasks using DINP on the day sampled, DiNP exposure in this company may be underestimated. The highest DiNP intake estimate was 26 mu g/kg/day. Conclusion: Occupational exposure to DiNP associated with PVC film manufacturing tasks were substantially higher (sixfold to tenfold) than adult general population exposures; however, all daily intake estimates were less than 25% of current United States or European acceptable or tolerable daily intake estimates. Further characterization of DiNP occupational exposures in other industries is recommended. JF - International Archives of Occupational and Environmental Health AU - Hines, Cynthia J AU - Hopf, Nancy B AU - Deddens, James A AU - Silva, Manori J AU - Calafat, Antonia M AD - National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, 4676 Columbia Pkwy, R-14, Cincinnati, OH, 45226, USA, chines@cdc.gov Y1 - 2012/04// PY - 2012 DA - Apr 2012 SP - 317 EP - 325 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 85 IS - 3 SN - 0340-0131, 0340-0131 KW - Health & Safety Science Abstracts KW - phthalates KW - USA KW - Urine KW - Chlorides KW - Metabolites KW - Occupational exposure KW - Pharmacokinetics KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1008841069?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Archives+of+Occupational+and+Environmental+Health&rft.atitle=Occupational+exposure+to+diisononyl+phthalate+%28DiNP%29+in+polyvinyl+chloride+processing+operations&rft.au=Hines%2C+Cynthia+J%3BHopf%2C+Nancy+B%3BDeddens%2C+James+A%3BSilva%2C+Manori+J%3BCalafat%2C+Antonia+M&rft.aulast=Hines&rft.aufirst=Cynthia&rft.date=2012-04-01&rft.volume=85&rft.issue=3&rft.spage=317&rft.isbn=&rft.btitle=&rft.title=International+Archives+of+Occupational+and+Environmental+Health&rft.issn=03400131&rft_id=info:doi/10.1007%2Fs00420-011-0674-z LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-01 N1 - Last updated - 2014-10-30 N1 - SubjectsTermNotLitGenreText - phthalates; Urine; Chlorides; Metabolites; Pharmacokinetics; Occupational exposure; USA DO - http://dx.doi.org/10.1007/s00420-011-0674-z ER - TY - JOUR T1 - HIV Risk Behavior Among HIV-Infected Men Who have Sex with Men in Bangkok, Thailand AN - 1008831085; 16505603 AB - We assessed prevalence of sexually transmitted infection (STIs), sexual risk behaviors, and factors associated with risk behaviors among HIV-infected MSM attending a public STI clinic serving MSM in Bangkok, Thailand. Between October 2005-October 2007, 154 HIV-infected MSM attending the clinic were interviewed about sexual risk behaviors and evaluated for STIs. Patients were examined for genital ulcers and had serologic testing for syphilis and PCR testing for chlamydia and gonorrhea. Results showed that sexual intercourse in the last 3 months was reported by 131 men. Of these, 32% reported anal sex without a condom. STIs were diagnosed in 41%. Factors associated with having sex without a condom were having a steady male partner, having a female partner and awareness of HIV status <1 month. Sexual risk behaviors and STIs were common among HIV-infected MSM in this study. This highlights the need for increased HIV prevention strategies for HIV-infected MSM. JF - AIDS and Behavior AU - Sirivongrangson, Pachara AU - Lolekha, Rangsima AU - Charoenwatanachokchai, Angkana AU - Siangphoe, Umaporn AU - Fox, Kimberley K AU - Jirarojwattana, Naiyana AU - Bollen, Liesbeth AU - Yenyarsan, Naruemon AU - Lokpichat, Somchai AU - Suksripanich, Orapin AU - McConnell, Michelle AD - Sexually Transmitted Infection Cluster, Bureau of AIDS/TB/STIs, Department of Disease Control, Ministry of Public Health (MOPH), Bangkok, Thailand, RangsimaL@th.cdc.gov Y1 - 2012/04// PY - 2012 DA - Apr 2012 SP - 618 EP - 625 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 16 IS - 3 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - Acquired immune deficiency syndrome KW - Condoms KW - Gonorrhea KW - Homosexuality KW - Human immunodeficiency virus KW - Infection KW - Infectious diseases KW - Polymerase chain reaction KW - Prevention KW - Sex KW - Sexual behavior KW - Sexual intercourse KW - Sexually transmitted diseases KW - Syphilis KW - Ulcers KW - anal sex KW - Thailand, Chacoengsao Prov., Bangkok KW - Treponema pallidum KW - Chlamydia KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1008831085?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=HIV+Risk+Behavior+Among+HIV-Infected+Men+Who+have+Sex+with+Men+in+Bangkok%2C+Thailand&rft.au=Sirivongrangson%2C+Pachara%3BLolekha%2C+Rangsima%3BCharoenwatanachokchai%2C+Angkana%3BSiangphoe%2C+Umaporn%3BFox%2C+Kimberley+K%3BJirarojwattana%2C+Naiyana%3BBollen%2C+Liesbeth%3BYenyarsan%2C+Naruemon%3BLokpichat%2C+Somchai%3BSuksripanich%2C+Orapin%3BMcConnell%2C+Michelle&rft.aulast=Sirivongrangson&rft.aufirst=Pachara&rft.date=2012-04-01&rft.volume=16&rft.issue=3&rft.spage=618&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-011-9884-3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-01 N1 - Last updated - 2012-05-18 N1 - SubjectsTermNotLitGenreText - Condoms; anal sex; Ulcers; Polymerase chain reaction; Gonorrhea; Infection; Syphilis; Sexual intercourse; Sexual behavior; Sex; Prevention; Acquired immune deficiency syndrome; Infectious diseases; Human immunodeficiency virus; Homosexuality; Sexually transmitted diseases; Treponema pallidum; Chlamydia; Thailand, Chacoengsao Prov., Bangkok DO - http://dx.doi.org/10.1007/s10461-011-9884-3 ER - TY - JOUR T1 - Myocardial Injury and Bacterial Pneumonia Contribute to the Pathogenesis of Fatal Influenza B Virus Infection AN - 1639990154; 20933614 AB - Background. Influenza B virus infection causes rates of hospitalization and influenza-associated pneumonia similar to seasonal influenza A virus infection and accounts for a substantial percentage of all influenza-related hospitalizations and deaths among those aged 18 years. Pathologic evidence of myocardial injury was identified in 69% of case patients for whom cardiac tissue samples were available for examination, predominantly in case patients aged ,18 years. Conclusions. Our findings suggest that bacterial pneumonia and cardiac injury contribute to fatal outcomes after infection with influenza B virus and that the frequency of these manifestations may be age related. JF - Journal of Infectious Diseases AU - Paddock, Christopher D AU - Liu, Lindy AU - Denison, Amy M AU - Bartlett, Jeanine H AU - Holman, Robert C AU - DeLeon-Carnes, Marlene AU - Emery, Shannon L AU - Drew, Clifton P AU - Shieh, Wun-Ju AU - Uyeki, Timothy M AU - Zaki, Sherif R AD - Infectious Diseases Pathology Branch, Mailstop G-32, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA 30333, cdp9@cdc.gov Y1 - 2012/03/15/ PY - 2012 DA - 2012 Mar 15 SP - 895 EP - 905 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 205 IS - 6 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts; Microbiology Abstracts B: Bacteriology KW - Light microscopy KW - Heart KW - submucosal gland KW - Mortality KW - Autopsy KW - Age KW - Injuries KW - Tropism KW - Pathogens KW - Infection KW - Influenza B virus KW - Influenza KW - Sulfur dioxide KW - Infectious diseases KW - Influenza A virus KW - Staphylococcus aureus KW - Seasonal variations KW - Pneumonia KW - Respiratory tract KW - H 1000:Occupational Safety and Health KW - J 02400:Human Diseases KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1639990154?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Myocardial+Injury+and+Bacterial+Pneumonia+Contribute+to+the+Pathogenesis+of+Fatal+Influenza+B+Virus+Infection&rft.au=Paddock%2C+Christopher+D%3BLiu%2C+Lindy%3BDenison%2C+Amy+M%3BBartlett%2C+Jeanine+H%3BHolman%2C+Robert+C%3BDeLeon-Carnes%2C+Marlene%3BEmery%2C+Shannon+L%3BDrew%2C+Clifton+P%3BShieh%2C+Wun-Ju%3BUyeki%2C+Timothy+M%3BZaki%2C+Sherif+R&rft.aulast=Paddock&rft.aufirst=Christopher&rft.date=2012-03-15&rft.volume=205&rft.issue=6&rft.spage=895&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjir861 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-12-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - submucosal gland; Heart; Autopsy; Age; Injuries; Tropism; Pathogens; Infection; Pneumonia; Respiratory tract; Light microscopy; Influenza; Mortality; Sulfur dioxide; Infectious diseases; Seasonal variations; Influenza A virus; Staphylococcus aureus; Influenza B virus DO - http://dx.doi.org/10.1093/infdis/jir861 ER - TY - JOUR T1 - Recommendations on modern contact investigation methods for enhancing tuberculosis control AN - 968176114; 16450019 AB - Effective contact investigations are paramount to the success of tuberculosis (TB) control in high-risk communities in low TB prevalence countries. National and international guidelines on TB contact investigations are available and vary widely on recommendations. Because of the limitations of traditional contact tracing, new approaches are under investigation, and in some cases in use, to ensure effective TB control in those persons and communities at greatest risk. These non-traditional approaches include the use of social network analysis, geographic information systems and genomics, in addition to the widespread use of genotyping, to better understand TB transmission. Detailed guidelines for the use of these methods during TB outbreaks and in routine follow-up of TB contact investigations do not currently exist despite evidence that they may improve TB control efforts. It remains unclear as to when it is most appropriate and effective to use a network-informed approach alone, or in combination with other methodologies as well as the extent of data collection required to inform practice. TB controllers should consider developing the capacity to facilitate the systematic collection, analysis, and interpretation of contact investigation data using such novel methodologies, particularly in high-risk communities. Further investigation should focus on questionnaire development and adaptation, electronic data management and infrastructure, development of local capability and consultant expertise, and the use of coordinated approaches, including deployment strategies and evaluation. JF - International Journal of Tuberculosis and Lung Disease AU - Cook, V J AU - Shah, L AU - Gardy, J AU - Bourgeois, A-C AD - BC Center for Disease Control-TB Control, 655 West 12th Avenue, Vancouver, British Columbia V5Z 4R4, Canada, victoria.cook@bccdc.ca Y1 - 2012/03// PY - 2012 DA - Mar 2012 SP - 297 EP - 305 PB - International Union Against Tuberculosis and Lung Disease VL - 16 IS - 3 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology KW - Inventories KW - Adaptations KW - Data processing KW - Mycobacterium KW - Genotyping KW - Lung diseases KW - Data collections KW - Contact tracing KW - Social interactions KW - Disease transmission KW - Risk factors KW - Risk groups KW - Tuberculosis KW - Geographic information systems KW - genomics KW - J 02310:Genetics & Taxonomy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/968176114?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Recommendations+on+modern+contact+investigation+methods+for+enhancing+tuberculosis+control&rft.au=Cook%2C+V+J%3BShah%2C+L%3BGardy%2C+J%3BBourgeois%2C+A-C&rft.aulast=Cook&rft.aufirst=V&rft.date=2012-03-01&rft.volume=16&rft.issue=3&rft.spage=297&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Inventories; Data processing; Adaptations; Genotyping; Lung diseases; Data collections; Contact tracing; Disease transmission; Social interactions; Risk factors; Risk groups; Tuberculosis; genomics; Geographic information systems; Mycobacterium ER - TY - JOUR T1 - Concordance of programmatic and laboratory-based multidrug-resistant tuberculosis treatment outcomes in Peru AN - 968171607; 16450030 AB - BACKGROUND: Confirmation of cure for multidrug-resistant tuberculosis (MDR-TB) patients requires laboratory tests for Mycobacterium tuberculosis growth on culture media. Outcome decisions dictate patient management, and inaccuracies place patients at an increased risk of morbidity and mortality, and may contribute to continued transmission of MDR-TB. OBJECTIVE: To examine concordance between programmatic and laboratory-based MDR-TB treatment outcomes. METHODS: The study population included 1658 MDR-TB patients in Peru treated between 1996 and 2002 with both program and laboratory-based outcomes. Laboratory-based outcomes were assigned according to international standards requiring at least five consecutive negative cultures in the last 12 months of treatment to confirm cure. RESULTS: Compared to the global culture-defined standard classification, only 1.1% of treatment successes, but 54.3% of failures, were misclassified programmatically. Overall, 10.4% of patients identified by a clinician as having a successful treatment outcome still had cultures positive for MDR-TB. CONCLUSION: Most patients with successful treatment outcomes by strict culture definitions were also classified by clinicians as having successful outcomes. However, many culture-confirmed failures were missed. In light of delays and incomplete access to culture in MDR-TB programs, efforts should be made to improve the accuracy of programmatically determined treatment outcomes. JF - International Journal of Tuberculosis and Lung Disease AU - Alexy, E R AU - Podewils, L J AU - Mitnick, C D AU - Becerra, M C AU - Laserson, K F AU - Bonillan, C AD - Division of Tuberculosis Elimination, US Centers for Disease Control and Prevention, 1600 Clifton Road NE, MS E-10, Atlanta, GA 30333, USA, Ipp8@cdc.gov Y1 - 2012/03// PY - 2012 DA - Mar 2012 SP - 364 EP - 369 PB - International Union Against Tuberculosis and Lung Disease VL - 16 IS - 3 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology; Risk Abstracts KW - Mortality KW - Laboratory testing KW - Drug resistance KW - Lung diseases KW - Population studies KW - Morbidity KW - tuberculosis KW - International standards KW - Classification KW - Lung KW - classification KW - Peru KW - Tuberculosis KW - Media (culture) KW - Mycobacterium tuberculosis KW - International standardization KW - J 02400:Human Diseases KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/968171607?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Concordance+of+programmatic+and+laboratory-based+multidrug-resistant+tuberculosis+treatment+outcomes+in+Peru&rft.au=Alexy%2C+E+R%3BPodewils%2C+L+J%3BMitnick%2C+C+D%3BBecerra%2C+M+C%3BLaserson%2C+K+F%3BBonillan%2C+C&rft.aulast=Alexy&rft.aufirst=E&rft.date=2012-03-01&rft.volume=16&rft.issue=3&rft.spage=364&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Mortality; International standards; Classification; Drug resistance; Lung diseases; Population studies; Tuberculosis; Media (culture); Morbidity; tuberculosis; Laboratory testing; Lung; classification; International standardization; Mycobacterium tuberculosis; Peru ER - TY - JOUR T1 - Rifampicin-resistant Mycobacterium tuberculosis: susceptibility to isoniazid and other anti-tuberculosis drugs AN - 968171575; 16450028 AB - Based on data from 14 Supranational Tuberculosis (TB) Reference Laboratories worldwide, the proportion of rifampicin (RMP) resistant isolates that were isoniazid (INH) susceptible by phenotypic drug susceptibility testing varied widely (0.5-11.6%). RMP-resistant isolates that were INH-susceptible had significantly lower rates of resistance to other first- and second-line anti-tuberculosis drugs (except rifabutin) compared to multidrug-resistant isolates. RMP resistance is not always a good proxy for a presumptive diagnosis of multidrug-resistant TB, which has implications for use of molecular assays that identify only RMP resistance-associated DNA mutations. JF - International Journal of Tuberculosis and Lung Disease AU - Kurbatova, E V AU - Cavanaugh, J S AU - Shah, N S AU - Wright, A AU - Kim, H AU - Metchock, B AU - Van Deun, A AU - Barrera, L AU - Boulahbal, F AU - Richter, E AU - Martin-Casabona, N AU - Arias, F AU - Zemanova, I AU - Drobniewski, F AD - International Research and Programs Branch, Division of Tuberculosis Elimi nation, CDC, Mailstop E-10, 1600 Clifton Road NE, Atlanta, Georgia 30333, USA, ekurbatova@cdc.gov Y1 - 2012/03// PY - 2012 DA - Mar 2012 SP - 355 EP - 357 PB - International Union Against Tuberculosis and Lung Disease VL - 16 IS - 3 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology KW - Rifampin KW - Data processing KW - Rifabutin KW - Drug resistance KW - Lung diseases KW - DNA KW - Tuberculosis KW - Drugs KW - Mutation KW - Mycobacterium tuberculosis KW - Isoniazid KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/968171575?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Rifampicin-resistant+Mycobacterium+tuberculosis%3A+susceptibility+to+isoniazid+and+other+anti-tuberculosis+drugs&rft.au=Kurbatova%2C+E+V%3BCavanaugh%2C+J+S%3BShah%2C+N+S%3BWright%2C+A%3BKim%2C+H%3BMetchock%2C+B%3BVan+Deun%2C+A%3BBarrera%2C+L%3BBoulahbal%2C+F%3BRichter%2C+E%3BMartin-Casabona%2C+N%3BArias%2C+F%3BZemanova%2C+I%3BDrobniewski%2C+F&rft.aulast=Kurbatova&rft.aufirst=E&rft.date=2012-03-01&rft.volume=16&rft.issue=3&rft.spage=355&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Rifampin; Rifabutin; Data processing; Drug resistance; DNA; Lung diseases; Tuberculosis; Mutation; Drugs; Isoniazid; Mycobacterium tuberculosis ER - TY - JOUR T1 - Bartonella species in bat flies (Diptera: Nycteribiidae) from western Africa AN - 968170516; 16341547 AB - Bat flies are obligate ectoparasites of bats and it has been hypothesized that they may be involved in the transmission of Bartonella species between bats. A survey was conducted to identify whether Cyclopodia greefi greefi (Diptera: Nycteribiidae) collected from Ghana and 2 islands in the Gulf of Guinea harbour Bartonella. In total, 137 adult flies removed from Eidolon helvum, the straw-coloured fruit bat, were screened for the presence of Bartonella by culture and PCR analysis. Bartonella DNA was detected in 91 (66.4%) of the specimens examined and 1 strain of a Bartonella sp., initially identified in E. helvum blood from Kenya, was obtained from a bat fly collected in Ghana. This is the first study, to our knowledge, to report the identification and isolation of Bartonella in bat flies from western Africa. JF - Parasitology AU - Billeter, Sa AU - HAYMAN, DTS AU - Peel, A J AU - Baker, K AU - WOOD, JLN AU - Cunningham, A AU - SUU-IRE, R AU - Dittmar, K AU - Kosoy, My AD - Centers for Disease Control and Prevention, Division of Vector Borne Diseases, Fort Collins, Colorado, USA, mck3@cdc.gov Y1 - 2012/03// PY - 2012 DA - Mar 2012 SP - 324 EP - 329 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 139 IS - 3 SN - 0031-1820, 0031-1820 KW - Entomology Abstracts; Microbiology Abstracts B: Bacteriology KW - Blood KW - Fruits KW - Islands KW - Polymerase chain reaction KW - ectoparasites KW - Bartonella KW - Eidolon helvum KW - Nycteribiidae KW - Diptera KW - Z 05300:General KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/968170516?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Parasitology&rft.atitle=Bartonella+species+in+bat+flies+%28Diptera%3A+Nycteribiidae%29+from+western+Africa&rft.au=Billeter%2C+Sa%3BHAYMAN%2C+DTS%3BPeel%2C+A+J%3BBaker%2C+K%3BWOOD%2C+JLN%3BCunningham%2C+A%3BSUU-IRE%2C+R%3BDittmar%2C+K%3BKosoy%2C+My&rft.aulast=Billeter&rft.aufirst=Sa&rft.date=2012-03-01&rft.volume=139&rft.issue=3&rft.spage=324&rft.isbn=&rft.btitle=&rft.title=Parasitology&rft.issn=00311820&rft_id=info:doi/10.1017%2FS0031182011002113 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-01 N1 - Number of references - 25 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - Fruits; Blood; Islands; Polymerase chain reaction; ectoparasites; Bartonella; Nycteribiidae; Diptera; Eidolon helvum DO - http://dx.doi.org/10.1017/S0031182011002113 ER - TY - JOUR T1 - Transmission dynamics of primary pneumonic plague in the USA AN - 968167446; 16287762 AB - Plague is thought to have killed millions during three catastrophic pandemics. Primary pneumonic plague, the most severe form of the disease, is transmissible from person-to-person and has the potential for propagating epidemics. Efforts to quantify its transmission potential have relied on published data from large outbreaks, an approach that artificially inflates the basic reproductive number (R0) and skews the distribution of individual infectiousness. Using data for all primary pneumonic plague cases reported in the USA from 1900 to 2009, we determined that the majority of cases will fail to transmit, even in the absence of antimicrobial treatment or prophylaxis. Nevertheless, potential for sustained outbreaks still exists due to superspreading events. These findings challenge current concepts regarding primary pneumonic plague transmission. JF - Epidemiology and Infection AU - Hinckley, A F AU - Biggerstaff, B J AU - Griffith, K S AU - Mead, P S AD - Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, CO, USA, ahinckley@cdc.gov Y1 - 2012/03// PY - 2012 DA - Mar 2012 SP - 554 EP - 560 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 140 IS - 3 SN - 0950-2688, 0950-2688 KW - Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts KW - USA KW - pandemics KW - Data processing KW - Epidemics KW - Reviews KW - Prophylaxis KW - Outbreaks KW - Plague KW - Disease transmission KW - Antimicrobial agents KW - H 12000:Epidemiology and Public Health KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/968167446?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Transmission+dynamics+of+primary+pneumonic+plague+in+the+USA&rft.au=Hinckley%2C+A+F%3BBiggerstaff%2C+B+J%3BGriffith%2C+K+S%3BMead%2C+P+S&rft.aulast=Hinckley&rft.aufirst=A&rft.date=2012-03-01&rft.volume=140&rft.issue=3&rft.spage=554&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268811001245 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-01 N1 - Number of references - 26 N1 - Last updated - 2013-07-26 N1 - SubjectsTermNotLitGenreText - pandemics; Epidemics; Data processing; Reviews; Prophylaxis; Plague; Antimicrobial agents; Disease transmission; Outbreaks; USA DO - http://dx.doi.org/10.1017/S0950268811001245 ER - TY - JOUR T1 - Haemophilus influenzae type b infection, vaccination, and H. influenzae carriage in children in Minnesota, 2008-2009 AN - 926903462; 16287772 AB - An increase in invasive Haemophilus influenzae type b (Hib) cases occurred in Minnesota in 2008 after the recommended deferral of the 12-15 months Hib vaccine boosters during a US vaccine shortage. Five invasive Hib cases (one death) occurred in children; four had incomplete Hib vaccination (three refused/delayed); one was immunodeficient. Subsequently, we evaluated Hib carriage and vaccination. From 18 clinics near Hib cases, children (aged 4 weeks-60 months) were surveyed for pharyngeal Hib carriage. Records were compared for Hib, diphtheria-tetanus-acellular pertussis (DTaP), and pneumococcal (PCV-7) vaccination. Parents completed questionnaires on carriage risk factors and vaccination beliefs. In 1631 children (February-March 2009), no Hib carriage was detected; Hib vaccination was less likely to be completed than DTaP and PCV-7. Non-type b H. influenzae, detected in 245 (15%) children, was associated with: male sex, age 24-60 months, daycare attendance >15 h/week, a household smoker, and Asian/Pacific Islander race/ethnicity. In 2009, invasive Hib disease occurred in two children caused by the same strain that circulated in 2008. Hib remains a risk for vulnerable/unvaccinated children, although Hib carriage is not widespread in young children. JF - Epidemiology and Infection AU - Lowther, Sa AU - Shinoda, N AU - Juni, Ba AU - Theodore, MJ AU - Wang, X AU - Jawahir, S L AU - Jackson, M L AU - Cohn, A AU - Danila, R AU - Lynfield, R AD - Epidemic Intelligence Service, Division of Applied Sciences, Scientific Education and Professional Development Program Office, Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA, sgl6@cdc.gov Y1 - 2012/03// PY - 2012 DA - Mar 2012 SP - 566 EP - 574 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 140 IS - 3 SN - 0950-2688, 0950-2688 KW - Immunology Abstracts; Microbiology Abstracts B: Bacteriology; Risk Abstracts KW - Daycare KW - Pertussis KW - vaccines KW - Age KW - Pharynx KW - Immunodeficiency KW - Infection KW - households KW - Risk factors KW - I, Pacific KW - infection KW - Races KW - Ethnic groups KW - Sex KW - Mortality KW - Inventories KW - Haemophilus influenzae KW - Children KW - Vaccination KW - USA, Minnesota KW - Streptococcus pneumoniae KW - daycare KW - vulnerability KW - Vaccines KW - J 02350:Immunology KW - R2 23060:Medical and environmental health KW - F 06910:Microorganisms & Parasites UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/926903462?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Haemophilus+influenzae+type+b+infection%2C+vaccination%2C+and+H.+influenzae+carriage+in+children+in+Minnesota%2C+2008-2009&rft.au=Lowther%2C+Sa%3BShinoda%2C+N%3BJuni%2C+Ba%3BTheodore%2C+MJ%3BWang%2C+X%3BJawahir%2C+S+L%3BJackson%2C+M+L%3BCohn%2C+A%3BDanila%2C+R%3BLynfield%2C+R&rft.aulast=Lowther&rft.aufirst=Sa&rft.date=2012-03-01&rft.volume=140&rft.issue=3&rft.spage=566&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268811000793 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Number of references - 38 N1 - Last updated - 2013-07-26 N1 - SubjectsTermNotLitGenreText - Pertussis; Daycare; Inventories; Age; Pharynx; Immunodeficiency; Children; Infection; Vaccination; Risk factors; Vaccines; Ethnic groups; Races; Sex; Mortality; households; vaccines; daycare; infection; vulnerability; Streptococcus pneumoniae; Haemophilus influenzae; I, Pacific; USA, Minnesota DO - http://dx.doi.org/10.1017/S0950268811000793 ER - TY - JOUR T1 - A CART technique to adjust production from longwall coal operations under ventilation constraints AN - 920792507; 16208863 AB - Methane emissions in longwall coal mines can arise from a variety of geologic and production factors, where ventilation and degasification are primary control measures to prevent excessive methane levels. However, poor ventilation practices or inadequate ventilation may result in accumulation of dangerous methane-air mixtures. The need exists for a set of rules and a model to be used as guidelines to adjust coal production according to expected methane emissions and current ventilation conditions. In this paper, hierarchical classification and regression tree (CART) analyses are performed as nonparametric modeling efforts to predict methane emissions that can arise during extraction of a longwall panel. These emissions are predicted for a range of coal productivities while considering specific operational, panel design and geologic parameters such as gas content, proximate composition of coal, seam height, panel width, cut height, cut depth, and panel size. Analyses are conducted for longwall mines with and without degasification of the longwall panel. These models define a range of coal productivities that can be achieved without exceeding specified emissions rates under given operating and geological conditions. Finally, the technique was applied to longwall mines that operate with and without degasification system to demonstrate its use and predictive capability. The predicted results proved to be close to the actual measurements to estimate ventilation requirements. Thus, the CART-based model that is given in this paper can be used to predict methane emission rates and to adjust operation parameters under ventilation constrains in longwall mining. JF - Safety Science AU - Karacan, COezgen AU - Goodman, Gerrit VR AD - National Institute of Occupational Safety and Health (NIOSH), Office of Mine Safety and Health Research (OMSHR), Dust Control, Ventilation, and Toxic Substances Branch, Pittsburgh, PA 15236, United States, cok6@cdc.gov Y1 - 2012/03// PY - 2012 DA - Mar 2012 SP - 510 EP - 522 PB - Elsevier B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 50 IS - 3 SN - 0925-7535, 0925-7535 KW - Health & Safety Science Abstracts KW - Mining safety KW - Coal mine methane KW - Methane emissions KW - Longwall mines KW - CART analyses KW - Methane KW - safety engineering KW - Ventilation KW - guidelines KW - Emissions KW - Emission measurements KW - Geology KW - Coal KW - Mines KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/920792507?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Safety+Science&rft.atitle=A+CART+technique+to+adjust+production+from+longwall+coal+operations+under+ventilation+constraints&rft.au=Karacan%2C+COezgen%3BGoodman%2C+Gerrit+VR&rft.aulast=Karacan&rft.aufirst=COezgen&rft.date=2012-03-01&rft.volume=50&rft.issue=3&rft.spage=510&rft.isbn=&rft.btitle=&rft.title=Safety+Science&rft.issn=09257535&rft_id=info:doi/10.1016%2Fj.ssci.2011.11.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-02-01 N1 - Last updated - 2015-04-09 N1 - SubjectsTermNotLitGenreText - Methane; safety engineering; Ventilation; guidelines; Emission measurements; Emissions; Geology; Coal; Mines DO - http://dx.doi.org/10.1016/j.ssci.2011.11.002 ER - TY - JOUR T1 - Libby vermiculite exposure and risk of developing asbestos-related lung and pleural diseases. AN - 918034481; 22139761 AB - The vermiculite ore formerly mined in Libby, Montana, contains asbestiform amphibole fibers of winchite, richterite, and tremolite asbestos. Because of the public health impact of widespread occupational and nonoccupational exposure to amphiboles in Libby vermiculite, numerous related studies have been published in recent years. Here we review current research related to this issue. Excess morbidity and mortality classically associated with asbestos exposure have been well documented among persons exposed to Libby vermiculite. Excess morbidity and mortality have likewise been documented among persons with only nonoccupational exposure. A strong exposure-response relationship exists for many malignant and nonmalignant outcomes and the most common outcome, pleural plaques, may occur at low lifetime cumulative exposures. The public health situation related to Libby, Montana, has led to huge investments in public health actions and research. The resulting studies have added much to the body of knowledge concerning health effects of exposures to Libby amphibole fibers specifically and asbestos exposure in general. JF - Current opinion in pulmonary medicine AU - Antao, Vinicius C AU - Larson, Theodore C AU - Horton, D Kevin AD - Division of Health Studies, Agency for Toxic Substances and Disease Registry, Atlanta, Georgia, USA. VAntao@cdc.gov Y1 - 2012/03// PY - 2012 DA - March 2012 SP - 161 EP - 167 VL - 18 IS - 2 KW - Aluminum Silicates KW - 0 KW - Asbestos, Amphibole KW - vermiculite KW - 1318-00-9 KW - Index Medicus KW - Risk Factors KW - Humans KW - Montana -- epidemiology KW - Cohort Studies KW - Mining KW - Male KW - Female KW - Asbestosis -- immunology KW - Lung Neoplasms -- epidemiology KW - Pleural Neoplasms -- chemically induced KW - Asbestosis -- epidemiology KW - Aluminum Silicates -- adverse effects KW - Lung Neoplasms -- immunology KW - Pleural Neoplasms -- epidemiology KW - Occupational Exposure -- adverse effects KW - Lung Neoplasms -- chemically induced KW - Pleural Neoplasms -- immunology KW - Asbestos, Amphibole -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/918034481?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Current+opinion+in+pulmonary+medicine&rft.atitle=Libby+vermiculite+exposure+and+risk+of+developing+asbestos-related+lung+and+pleural+diseases.&rft.au=Antao%2C+Vinicius+C%3BLarson%2C+Theodore+C%3BHorton%2C+D+Kevin&rft.aulast=Antao&rft.aufirst=Vinicius&rft.date=2012-03-01&rft.volume=18&rft.issue=2&rft.spage=161&rft.isbn=&rft.btitle=&rft.title=Current+opinion+in+pulmonary+medicine&rft.issn=1531-6971&rft_id=info:doi/10.1097%2FMCP.0b013e32834e897d LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-03-22 N1 - Date created - 2012-01-25 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1097/MCP.0b013e32834e897d ER - TY - JOUR T1 - Community and Health Worker Perceptions and Preferences Regarding Integration of Other Health Services With Routine Vaccinations: Four Case Studies AN - 1627968500; 20933609 AB - Background. Integration of routine vaccination and other maternal and child health services is becoming more common and the services being integrated more diverse. Yet knowledge gaps remain regarding community members and health workers acceptance, priorities, and concerns related to integration. Methods. Qualitative health worker interviews and community focus groups were conducted in 4 African countries (Kenya, Mali, Ethiopia, and Cameroon). Results. Integration was generally well accepted by both community members and health workers. Most integrated services were perceived positively by the communities, although perceptions around socially sensitive services (eg, family planning and human immunodeficiency virus) differed by country. Integration benefits reported by both community members and health workers across countries included opportunity to receive multiple services at one visit, time and transportation cost savings, increased service utilization, maximized health worker efficiency, and reduced reporting requirements. Concerns related to integration included being labor intensive, inadequate staff to implement, inadequately trained staff, in addition to a number of more broad health system issues (eg, stockouts, wait times). Conclusions. Communities generally supported integration, and integrated services may have the potential to increase service utilization and possibly even reduce the stigma of certain services. Some concerns expressed related to health system issues rather than integration, per se, and should be addressed as part of a wider approach to improve health services. Improved planning and patient flow and increasing the number and training of health staff may help to mitigate logistical challenges of integrating services. JF - Journal of Infectious Diseases AU - Ryman, Tove K AU - Wallace, Aaron AU - Mihigo, Richard AU - Richards, Patricia AU - Schlanger, Karen AU - Cappelier, Kelli AU - Ndiaye, Serigne AU - Modjirom, Ndoutabe AU - Tounkara, Baba AU - Grant, Gavin AD - Global Immunization Division, US Centers for Disease Control and Prevention, Atlanta, Georgia; Centers for Disease Control and Prevention, 1600 Clifton Rd, MS-E05, Atlanta, GA 30307, tryman@cdc.gov Y1 - 2012/03/01/ PY - 2012 DA - 2012 Mar 01 SP - S49 EP - S55 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 205 SN - 0022-1899, 0022-1899 KW - Health & Safety Science Abstracts; Sustainability Science Abstracts KW - Family planning KW - Mali KW - Training KW - Ethiopia KW - Kenya KW - Transportation KW - Case studies KW - Infectious diseases KW - Perception KW - Human immunodeficiency virus KW - Priorities KW - Cameroon KW - Vaccines KW - M3 1010:Issues in Sustainable Development KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1627968500?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Community+and+Health+Worker+Perceptions+and+Preferences+Regarding+Integration+of+Other+Health+Services+With+Routine+Vaccinations%3A+Four+Case+Studies&rft.au=Ryman%2C+Tove+K%3BWallace%2C+Aaron%3BMihigo%2C+Richard%3BRichards%2C+Patricia%3BSchlanger%2C+Karen%3BCappelier%2C+Kelli%3BNdiaye%2C+Serigne%3BModjirom%2C+Ndoutabe%3BTounkara%2C+Baba%3BGrant%2C+Gavin&rft.aulast=Ryman&rft.aufirst=Tove&rft.date=2012-03-01&rft.volume=205&rft.issue=&rft.spage=S49&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjir796 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-11-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Family planning; Case studies; Transportation; Infectious diseases; Training; Human immunodeficiency virus; Perception; Priorities; Vaccines; Mali; Kenya; Ethiopia; Cameroon DO - http://dx.doi.org/10.1093/infdis/jir796 ER - TY - JOUR T1 - Sampling and mass spectrometric analytical methods for five antineoplastic drugs in the healthcare environment AN - 1443366850; 18507726 AB - Context. Healthcare worker exposure to antineoplastic drugs continues to be reported despite safe handling guidelines published by several groups. Sensitive sampling and analytical methods are needed so that occupational safety and health professionals may accurately assess environmental and biological exposure to these drugs in the workplace.Objective. To develop liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS) analytical methods for measuring five antineoplastic drugs in samples from the work environment, and to apply these methods in validating sampling methodology. A single method for quantifying several widely used agents would decrease the number of samples required for method development, lower cost, and time of analysis. Methods for measuring these drugs in workers' urine would also be useful in monitoring personal exposure levels.Results. LC-MS/MS methods were developed for individual analysis of five antineoplastic drugs in wipe and air sample media projected for use in field sampling: cyclophosphamide, ifosfamide, paclitaxel, doxorubicin, and 5-fluorouracil. Cyclophosphamide, ifosfamide, and paclitaxel were also measured simultaneously in some stages of the work. Extraction methods for air and wipe samples were developed and tested using the aforementioned analytical methods. Good recoveries from the candidate air and wipe sample media for most of the compounds, and variable recoveries for test wipe samples depending on the surface under study, were observed. Alternate LC-MS/MS methods were also developed to detect cyclophosphamide and paclitaxel in urine samples.Conclusions. The sampling and analytical methods were suitable for determining worker exposure to antineoplastics via surface and breathing zone contamination in projected surveys of healthcare settings. JF - Journal of Oncology Pharmacy Practice AU - Pretty, Jack R AU - Connor, Thomas H AU - Spasojevic, Ivan AU - Kurtz, Kristine S AU - McLaurin, Jeffrey L AU - B'Hymer, Clayton AU - Debord, D Gayle AD - Division of Applied Research and Technology, National Institute for Occupational Safety and Health, U.S. Centers for Disease Control and Prevention, Cincinnati, OH, USA  , jrp0@cdc.gov Y1 - 2012/03// PY - 2012 DA - Mar 2012 SP - 23 EP - 36 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU United Kingdom VL - 18 IS - 1 SN - 1078-1552, 1078-1552 KW - Health & Safety Science Abstracts KW - Health care KW - Urine KW - Guidelines KW - Air sampling KW - Antineoplastic drugs KW - Drugs KW - Occupational exposure KW - Medical personnel KW - Spectrometry KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1443366850?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Oncology+Pharmacy+Practice&rft.atitle=Sampling+and+mass+spectrometric+analytical+methods+for+five+antineoplastic+drugs+in+the+healthcare+environment&rft.au=Pretty%2C+Jack+R%3BConnor%2C+Thomas+H%3BSpasojevic%2C+Ivan%3BKurtz%2C+Kristine+S%3BMcLaurin%2C+Jeffrey+L%3BB%27Hymer%2C+Clayton%3BDebord%2C+D+Gayle&rft.aulast=Pretty&rft.aufirst=Jack&rft.date=2012-03-01&rft.volume=18&rft.issue=1&rft.spage=23&rft.isbn=&rft.btitle=&rft.title=Journal+of+Oncology+Pharmacy+Practice&rft.issn=10781552&rft_id=info:doi/10.1177%2F1078155210389215 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-10-01 N1 - Number of references - 28 N1 - Last updated - 2013-10-21 N1 - SubjectsTermNotLitGenreText - Health care; Urine; Guidelines; Air sampling; Antineoplastic drugs; Drugs; Medical personnel; Occupational exposure; Spectrometry DO - http://dx.doi.org/10.1177/1078155210389215 ER - TY - JOUR T1 - Post-Hire Asthma Among Insect-Rearing Workers AN - 1020856796; 16507823 AB - Objective: To evaluate the incidence of post-hire asthma (PHA) among insect-rearing workers, defined as asthma, the symptoms of which appeared after hire at the current workplace. Methods: We surveyed the health of workers at three insect-rearing facilities and an associated office facility. We calculated the incidence and estimated hazard ratios for PHA. Results: Post-hire asthma incidence in 157 insect-rearing workers was 16.2 per 1000 person-years compared with 9.2 per 1,000 person-years in 70 office workers. Workers with predominant exposure to Lepidoptera had an incidence of 26.9 per 1000 person-years and a hazard ratio of 5.5 (95% confidence interval: 1.6 to 23.9) adjusted for sex, race, and parental asthma. In contrast, the presence of specific immunoglobulin E to Lepidoptera antigens was not associated with PHA. Conclusion: Insect-rearing workers had a high incidence of PHA, primarily accounted for by workplace exposure to Lepidoptera. JF - Journal of Occupational and Environmental Medicine AU - Suarthana, E AU - Shen, A AU - Henneberger, P K AU - Kreiss, K AU - Leppla, N C AU - Bueller, D AU - Lewis, D M AU - Bledsoe, T A AU - Janotka, E AU - Petsonk, EL AD - Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, 1095 Willowdale Rd, Morgantown WV 26505, USA, elp2@cdc.gov Y1 - 2012/03// PY - 2012 DA - Mar 2012 SP - 310 EP - 317 VL - 54 IS - 3 SN - 1076-2752, 1076-2752 KW - Entomology Abstracts; Health & Safety Science Abstracts; Risk Abstracts KW - Workers KW - Immunoglobulin E KW - Asthma KW - Respiratory diseases KW - Occupational exposure KW - Lepidoptera KW - Z 05300:General KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1020856796?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Post-Hire+Asthma+Among+Insect-Rearing+Workers&rft.au=Suarthana%2C+E%3BShen%2C+A%3BHenneberger%2C+P+K%3BKreiss%2C+K%3BLeppla%2C+N+C%3BBueller%2C+D%3BLewis%2C+D+M%3BBledsoe%2C+T+A%3BJanotka%2C+E%3BPetsonk%2C+EL&rft.aulast=Suarthana&rft.aufirst=E&rft.date=2012-03-01&rft.volume=54&rft.issue=3&rft.spage=310&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e31823fe098 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-06-01 N1 - Last updated - 2013-06-28 N1 - SubjectsTermNotLitGenreText - Workers; Immunoglobulin E; Asthma; Occupational exposure; Respiratory diseases; Lepidoptera DO - http://dx.doi.org/10.1097/JOM.0b013e31823fe098 ER - TY - JOUR T1 - Occupational Safety and Health in the USA: Now and the Future AN - 1014105073; 16644574 AB - In the USA, national worker protection legislation was enacted in 1970. The legislation required that research, recommendations and guidance be developed to aid employers and workers, that workplace health and safety standards be adopted, that employer comply with those rules and that the government police employer compliance, and that assistance be offered to employers and workers to help them maintain a safe and healthful workplace. In the 40 yr since passage of the Occupational Safety and Health Act of 1970, worker injury, illness and fatalities have declined but not been eliminated. Efforts to accelerate the standards adoption process are much discussed in the USA along with how to protect workers from emerging hazards like nanotechnology. New strategies which seek to eliminate not only the causes of work-related injury and illness, but also more broadly, worker injury and illness, are on the horizon. JF - Industrial Health AU - Howard, J AU - Hearl, F AD - National Institute for Occupational Safety and Health, Conters for Disease Control and Prevention, U.S. Department of Health and Human Services, 395 E Street, S.W., Suite 9200, Washington DC, USA, zkz1@cdc.gov Y1 - 2012/03// PY - 2012 DA - Mar 2012 SP - 80 EP - 83 VL - 50 IS - 2 SN - 0019-8366, 0019-8366 KW - Health & Safety Science Abstracts; Risk Abstracts KW - Mortality KW - USA KW - Injuries KW - police KW - Occupational safety KW - Compliance KW - Police KW - Legislation KW - nanotechnology KW - Nanotechnology KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1014105073?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Industrial+Health&rft.atitle=Occupational+Safety+and+Health+in+the+USA%3A+Now+and+the+Future&rft.au=Howard%2C+J%3BHearl%2C+F&rft.aulast=Howard&rft.aufirst=J&rft.date=2012-03-01&rft.volume=50&rft.issue=2&rft.spage=80&rft.isbn=&rft.btitle=&rft.title=Industrial+Health&rft.issn=00198366&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2013-05-31 N1 - SubjectsTermNotLitGenreText - Mortality; police; Injuries; Compliance; Occupational safety; Police; Legislation; Nanotechnology; nanotechnology; USA ER - TY - JOUR T1 - Comparison of DNA extraction methodologies used for assessing fungal diversity via ITS sequencing AN - 1008847150; 16532904 AB - Traditional methods of assessing fungal exposure have been confounded by a number of limiting variables. The recent utilization of molecular methods such as internal transcribed spacer (ITS) sequencing of ribosomal RNA genes has provided improved insight into the diversity of fungal bioaerosols in indoor, outdoor and occupational environments. However, ITS analyses may also be confounded by a number of methodological limitations. In this study, we have optimized this technology for use in occupational or environmental studies. Three commonly used DNA extraction methodologies (UltraClean Soil kit, High Pure PCR Template kit, and EluQuik/DNeasy kit) were compared in terms of sensitivity and susceptibility to PCR inhibitors in dust for three common fungal bioaerosols, Aspergillus versicolor, Rhizopus microsporus and Wallemia sebi. Environmental dust samples were then studied using each extraction methodology and results were compared to viable culture data. The extraction methods differed in terms of their ability to efficiently extract DNA from particular species of fungi (e.g. Aspergillus versicolor). In addition, the ability to remove PCR inhibitors from dust samples was most effective using the soil DNA extraction kit. The species composition varied greatly between ITS clone libraries generated with the different DNA extraction kits. However, compared to viable culture data, ITS clone libraries included additional fungal species that are incapable of growth on solid culture medium. Collectively, our data indicated that DNA extraction methodologies used in ITS sequencing studies of occupational or environmental dust samples can greatly influence the fungal species that are detected. JF - Journal of Environmental Monitoring AU - Rittenour, W R AU - Park, J-H AU - Cox-Ganser, J M AU - Beezhold, D H AU - Green, B J AD - Allergy and Clinical Immunology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Rd., Morgantown, West Virginia, USA, ikx8@cdc.gov Y1 - 2012/03// PY - 2012 DA - Mar 2012 SP - 766 EP - 774 VL - 14 IS - 3 SN - 1464-0325, 1464-0325 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Biochemistry Abstracts 2: Nucleic Acids; Environment Abstracts; Pollution Abstracts KW - Aerosols KW - Aspergillus versicolor KW - DNA KW - Dust KW - P 0000:AIR POLLUTION KW - K 03450:Ecology KW - N 14810:Methods KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1008847150?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+Monitoring&rft.atitle=Comparison+of+DNA+extraction+methodologies+used+for+assessing+fungal+diversity+via+ITS+sequencing&rft.au=Rittenour%2C+W+R%3BPark%2C+J-H%3BCox-Ganser%2C+J+M%3BBeezhold%2C+D+H%3BGreen%2C+B+J&rft.aulast=Rittenour&rft.aufirst=W&rft.date=2012-03-01&rft.volume=14&rft.issue=3&rft.spage=766&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+Monitoring&rft.issn=14640325&rft_id=info:doi/10.1039%2Fc2em10779a LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-01 N1 - Last updated - 2014-02-11 N1 - SubjectsTermNotLitGenreText - Dust; DNA; Aspergillus versicolor DO - http://dx.doi.org/10.1039/c2em10779a ER - TY - JOUR T1 - A Consensus Method for Updating Psychosocial Measures Used in NIOSH Health Hazard Evaluations AN - 1008846064; 16507828 AB - Objective: An expert panel was convened to select practical, valid psychosocial measures for use during National Institute for Occupational Safety and Health field investigations. Methods: A taxonomy of psychosocial constructs was developed using existing taxonomies and criteria regarding the malleability, actionability, and validity of constructs. Panel members identified measures for each construct based on their expertise and experience. Measures were selected on the basis of the following criteria: practicality, brevity, validity, availability of existing data, and lack of confounds between psychosocial constructs and outcomes. Results: The panel came to a consensus in recommending 24 measures representing 22 constructs. Conclusions: It is important that the National Institute for Occupational Safety and Health regularly evaluates its methodologies to ensure it is in line with current best practices. The measures identified will be used modularly in the National Institute for Occupational Safety and Health fieldwork depending on the nature of the evaluation request, industry type, and worker population. JF - Journal of Occupational and Environmental Medicine AU - Wiegand, D M AU - Chen, P Y AU - Hurrell, JJ Jr AU - Jex, S AU - Nakata, A AU - Nigam, JA AU - Robertson, M AU - Tetrick, LE AD - NIOSH/DSHEFS/HETAB, 4676 Columbia Parkway (MS R-10), Cincinnati, OH 45226, USA, dwiegand@cdc.gov Y1 - 2012/03// PY - 2012 DA - Mar 2012 SP - 350 EP - 355 VL - 54 IS - 3 SN - 1076-2752, 1076-2752 KW - Health & Safety Science Abstracts; Risk Abstracts KW - Hazards KW - best practices KW - Fieldwork KW - Best practices KW - Occupational safety KW - Taxonomy KW - taxonomy KW - fieldwork KW - H 1000:Occupational Safety and Health KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1008846064?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=A+Consensus+Method+for+Updating+Psychosocial+Measures+Used+in+NIOSH+Health+Hazard+Evaluations&rft.au=Wiegand%2C+D+M%3BChen%2C+P+Y%3BHurrell%2C+JJ+Jr%3BJex%2C+S%3BNakata%2C+A%3BNigam%2C+JA%3BRobertson%2C+M%3BTetrick%2C+LE&rft.aulast=Wiegand&rft.aufirst=D&rft.date=2012-03-01&rft.volume=54&rft.issue=3&rft.spage=350&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e3182440a04 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-01 N1 - Last updated - 2013-06-28 N1 - SubjectsTermNotLitGenreText - Hazards; best practices; Fieldwork; Best practices; Occupational safety; Taxonomy; fieldwork; taxonomy DO - http://dx.doi.org/10.1097/JOM.0b013e3182440a04 ER - TY - JOUR T1 - Use of denuder/filter apparatus to investigate terpene ozonolysis AN - 1008840487; 16532929 AB - A denuder/filter apparatus was used to collect the gaseous and paniculate reaction products from ozonlysis of alpha -pinene, limonene and alpha -terpineol in an effort to develop sampling techniques for characterizing indoor environment chemistry. Carboxylic acids found in the paniculate phase were derivatized to 2,2,2-trifuoroethylamides by reaction with 3-ethyl-1-[3-(dimethylamino) propyl] carbodiimide hydrochloride (EDC) and 2,2,2-trifluoroethylamine hydrochloride (TFEA). Carbonyl compounds collected in both gas phase and paniculate phase were derivatized to their respective oximes by reaction with O-(2,3,4,5,6-pentafiuoro-benzyl) hydroxylamine hydrochloride (PFBHA). The ozonolysis of alpha -pinene yielded the carboxylic acids: cis-pinonic acid and pinic acid and the proposed carboxylic acids methanetricarboxylic acid and terpenylic acid; the carbonyls: 4-oxopentanal, norpinonaldehyde, pinon aldehyde and the proposed carbonyl methylidenepropanedial. The ozonolysis of limonene yielded the carboxylic acids: limonic acid and pinic acid and the carbonyls: 1-(4-methylcyclohex-3-en-1-yl) ethanone (4AMCH), glyoxal, methyl glyoxal, 4-oxopentanal and 6-oxo-3-(prop-1-en-2-yl) heptanal (IPOH). The ozonolysis of alpha -terpineol yielded the proposed carboxylic acids: terpenylic acid and homoterpenylic acid and the carbonyls: (5E)-6-hydroxyhept-5-en-2-one, methyl glyoxal and 4-oxopentanal. JF - Journal of Environmental Monitoring AU - Wells, J R AD - Exposure Assessment Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV, 26505, USA, ozw0@cdc.gov Y1 - 2012/03// PY - 2012 DA - Mar 2012 SP - 1044 EP - 1054 VL - 14 IS - 3 SN - 1464-0325, 1464-0325 KW - Pollution Abstracts; Environment Abstracts KW - Filters KW - Carboxylic acids KW - hydroxylamines KW - Aldehydes KW - Indoor environments KW - carbonyl compounds KW - Ozonation KW - P 9999:GENERAL POLLUTION KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1008840487?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+Monitoring&rft.atitle=Use+of+denuder%2Ffilter+apparatus+to+investigate+terpene+ozonolysis&rft.au=Wells%2C+J+R&rft.aulast=Wells&rft.aufirst=J&rft.date=2012-03-01&rft.volume=14&rft.issue=3&rft.spage=1044&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+Monitoring&rft.issn=14640325&rft_id=info:doi/10.1039%2Fc2em10799f LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-01 N1 - Last updated - 2013-06-28 N1 - SubjectsTermNotLitGenreText - Filters; Carboxylic acids; hydroxylamines; Indoor environments; Aldehydes; carbonyl compounds; Ozonation DO - http://dx.doi.org/10.1039/c2em10799f ER - TY - CPAPER T1 - Neighborhood-level risk factors for rural childhood stomach illness: Drinking water, agriculture, and socioeconomics T2 - 2012 Annual Meeting of the Association of American Geographers (AAG 2012) AN - 1412144810; 6217763 JF - 2012 Annual Meeting of the Association of American Geographers (AAG 2012) AU - Uejio, Christopher Y1 - 2012/02/24/ PY - 2012 DA - 2012 Feb 24 KW - Agriculture KW - Socio-economic aspects KW - Drinking Water KW - Risk factors KW - Drinking water KW - Children KW - Stomach KW - Rural areas UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1412144810?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2012+Annual+Meeting+of+the+Association+of+American+Geographers+%28AAG+2012%29&rft.atitle=Neighborhood-level+risk+factors+for+rural+childhood+stomach+illness%3A+Drinking+water%2C+agriculture%2C+and+socioeconomics&rft.au=Uejio%2C+Christopher&rft.aulast=Uejio&rft.aufirst=Christopher&rft.date=2012-02-24&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2012+Annual+Meeting+of+the+Association+of+American+Geographers+%28AAG+2012%29&rft.issn=&rft_id=info:doi/ L2 - http://meridian.aag.org/callforpapers/program/index.cfm?mtgID=57 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-06-30 N1 - Last updated - 2013-07-25 ER - TY - JOUR T1 - Preparation, certification and interlaboratory analysis of workplace air filters spiked with high-fired beryllium oxide AN - 968184977; 16507500 AB - Occupational sampling and analysis for multiple elements is generally approached using various approved methods from authoritative government sources such as the National Institute for Occupational Safety and Health (NIOSH), the Occupational Safety and Health Administration (OSHA) and the Environmental Protection Agency (EPA), as well as consensus standards bodies such as ASTM International. The constituents of a sample can exist as unidentified compounds requiring sample preparation to be chosen appropriately, as in the case of beryllium in the form of beryllium oxide (BeO). An interlaboratory study was performed to collect analytical data from volunteer laboratories to examine the effectiveness of methods currently in use for preparation and analysis of samples containing calcined BeO powder. NIST SRM registered 1877 high-fired BeO powder (1100 to 1200 degree C calcining temperature; count median primary particle diameter 0.12 mu m) was used to spike air filter media as a representative form of beryllium particulate matter present in workplace sampling that is known to be resistant to dissolution. The BeO powder standard reference material was gravimetrically prepared in a suspension and deposited onto 37 mm mixed cellulose ester air filters at five different levels between 0.5 mu g and 25 mu g of Be (as BeO). Sample sets consisting of five BeO-spiked filters (in duplicate) and two blank filters, for a total of twelve unique air filter samples per set, were submitted as blind samples to each of 27 participating laboratories. Participants were instructed to follow their current process for sample preparation and utilize their normal analytical methods for processing samples containing substances of this nature. Laboratories using more than one sample preparation and analysis method were provided with more than one sample set. Results from 34 data sets ultimately received from the 27 volunteer laboratories were subjected to applicable statistical analyses. The observed performance data show that sample preparations using nitric acid alone, or combinations of nitric and hydrochloric acids, are not effective for complete extraction of Be from the SRM 1877 refractory BeO particulate matter spiked on air filters; but that effective recovery can be achieved by using sample preparation procedures utilizing either sulfuric or hydrofluoric acid, or by using methodologies involving ammonium bifluoride with heating. Laboratories responsible for quantitative determination of Be in workplace samples that may contain high-fired BeO should use quality assurance schemes that include BeO-spiked sampling media, rather than solely media spiked with soluble Be compounds, and should ensure that methods capable of quantitative digestion of Be from the actual material present are used. JF - Journal of Environmental Monitoring AU - Oatts, T J AU - Hicks, CE AU - Adams, A R AU - Brisson, MJ AU - Youmans-McDonald, L D AU - Hoover, MD AU - Ashley, K AD - US Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Cincinnati, OH, 45226, USA, KAshley@cdc.gov Y1 - 2012/02// PY - 2012 DA - Feb 2012 SP - 391 EP - 401 VL - 14 IS - 2 SN - 1464-0325, 1464-0325 KW - Health & Safety Science Abstracts; Environment Abstracts; Sustainability Science Abstracts; Pollution Abstracts KW - Filters KW - Pollutant removal KW - EPA KW - Air purification KW - Beryllium KW - Occupational safety KW - Temperature KW - Particulates KW - International standardization KW - M3 1010:Issues in Sustainable Development KW - H 1000:Occupational Safety and Health KW - P 6000:TOXICOLOGY AND HEALTH KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/968184977?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+Monitoring&rft.atitle=Preparation%2C+certification+and+interlaboratory+analysis+of+workplace+air+filters+spiked+with+high-fired+beryllium+oxide&rft.au=Oatts%2C+T+J%3BHicks%2C+CE%3BAdams%2C+A+R%3BBrisson%2C+MJ%3BYoumans-McDonald%2C+L+D%3BHoover%2C+MD%3BAshley%2C+K&rft.aulast=Oatts&rft.aufirst=T&rft.date=2012-02-01&rft.volume=14&rft.issue=2&rft.spage=391&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+Monitoring&rft.issn=14640325&rft_id=info:doi/10.1039%2Fc1em10688k LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-01 N1 - Last updated - 2013-06-28 N1 - SubjectsTermNotLitGenreText - Filters; EPA; Pollutant removal; Air purification; Occupational safety; Beryllium; Temperature; Particulates; International standardization DO - http://dx.doi.org/10.1039/c1em10688k ER - TY - JOUR T1 - Interlaboratory evaluation of trace element determination in workplace air filter samples by inductively coupled plasma mass spectrometry AN - 968184718; 16507496 AB - Inductively coupled plasma mass spectrometry (ICP-MS) is becoming more widely used for trace elemental analysis in the occupational hygiene field, and consequently new ICP-MS international standard procedures have been promulgated by ASTM International and ISO. However, there is a dearth of interlaboratory performance data for this analytical methodology. In an effort to fill this data void, an interlaboratory evaluation of ICP-MS for determining trace elements in workplace air samples was conducted, towards fulfillment of method validation requirements for international voluntary consensus standard test methods. The study was performed in accordance with applicable statistical procedures for investigating interlaboratory precision. The evaluation was carried out using certified 37-mm diameter mixed-cellulose ester (MCE) filters that were fortified with 21 elements of concern in occupational hygiene. Elements were spiked at levels ranging from 0.025 to 10 mu g filter super(-1), with three different filter loadings denoted "Low", "Medium" and "High". Participating laboratories were recruited from a pool of over fifty invitees; ultimately twenty laboratories from Europe, North America and Asia submitted results. Triplicates of each certified filter with elemental contents at three different levels, plus media blanks spiked with reagent, were conveyed to each volunteer laboratory. Each participant was also provided a copy of the test method which each participant was asked to follow; spiking levels were unknown to the participants. The laboratories were requested to prepare the filters by one of three sample preparation procedures, i.e., hotplate digestion, microwave digestion or hot block extraction, which were described in the test method. Participants were then asked to analyze aliquots of the prepared samples by ICP-MS, and to report their data in units of mu g filter super(-1). Most interlaboratory precision estimates were acceptable for medium- and high-level spikes (RSD <25%), but generally yielded greater uncertainties than were anticipated at the outset of the study. JF - Journal of Environmental Monitoring AU - Ashley, K AU - Shulman, SA AU - Brisson, MJ AU - Howe, A M AD - US Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, M.S. R-7, Cincinnati, OH, 45226-1998, USA, KAshley@cdc.gov Y1 - 2012/02// PY - 2012 DA - Feb 2012 SP - 360 EP - 367 VL - 14 IS - 2 SN - 1464-0325, 1464-0325 KW - Environment Abstracts; Pollution Abstracts; Health & Safety Science Abstracts KW - Filters KW - Digestion KW - North America KW - Mass spectrometry KW - Europe KW - Asia KW - Esters KW - Occupational exposure KW - Occupational health KW - Trace elements KW - International standardization KW - P 0000:AIR POLLUTION KW - H 1000:Occupational Safety and Health KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/968184718?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+Monitoring&rft.atitle=Interlaboratory+evaluation+of+trace+element+determination+in+workplace+air+filter+samples+by+inductively+coupled+plasma+mass+spectrometry&rft.au=Ashley%2C+K%3BShulman%2C+SA%3BBrisson%2C+MJ%3BHowe%2C+A+M&rft.aulast=Ashley&rft.aufirst=K&rft.date=2012-02-01&rft.volume=14&rft.issue=2&rft.spage=360&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+Monitoring&rft.issn=14640325&rft_id=info:doi/10.1039%2Fc1em10695c LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-01 N1 - Last updated - 2013-06-28 N1 - SubjectsTermNotLitGenreText - Digestion; Filters; Mass spectrometry; Esters; Occupational exposure; International standardization; Trace elements; Occupational health; North America; Europe; Asia DO - http://dx.doi.org/10.1039/c1em10695c ER - TY - JOUR T1 - Genetic diversity and antibiotic resistance in Shigella dysenteriae and Shigella boydii strains isolated from children aged <5 years in Egypt AN - 968173472; 16162940 AB - Diversity within Shigella dysenteriae (n=40) and Shigella boydii (n=30) isolates from children living in Egypt aged <5 years was investigated. Shigella-associated diarrhoea occurred mainly in summer months and in children aged <3 years, it commonly presented with vomiting and fever. Serotypes 7 (30%), 2 (28%), and 3 (23%) accounted for most of S. dysenteriae isolates; 50% of S. boydii isolates were serotype 2. S. dysenteriae and S. boydii isolates were often resistant to ampicillin, chloramphenicol and tetracycline (42%, 17%, respectively), although resistance varied among serotypes. Pulsed-field gel electrophoresis separated the isolates into distinct clusters correlating with species and serotype. Genetic differences in trimethoprim/sulfamethoxazole and beta -lactam-encoding resistance genes were also evident. S. dysenteriae and S. boydii are genetically diverse pathogens in Egypt; the high level of multidrug resistance associated with both pathogens and resistance to the most available inexpensive antibiotics underlines the importance of continuing surveillance. JF - Epidemiology and Infection AU - El-Gendy, A M AU - Mansour, A AU - Weiner, Ma AU - Pimentel, G AU - Armstrong, A W AU - Young, Syn AU - Elsayed, N AU - Klena, J D AD - Clinical Trials and Military Studies Program, U.S. Naval Medical Research Unit No. 3, Cairo, Egypt, irc4@cn.cdc.gov Y1 - 2012/02// PY - 2012 DA - February 2012 SP - 299 EP - 310 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 140 IS - 2 SN - 0950-2688, 0950-2688 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Microbiology Abstracts B: Bacteriology KW - Egypt, Arab Rep. KW - Trimethoprim KW - Serotypes KW - Vomiting KW - Shigella boydii KW - Genetic diversity KW - Antibiotics KW - Tetracyclines KW - Shigella dysenteriae KW - Fever KW - Antibiotic resistance KW - Chloramphenicol KW - Diarrhea KW - Sulfamethoxazole KW - Surveillance and enforcement KW - Ampicillin KW - Pathogens KW - Children KW - Strains KW - Control resistance KW - Epidemiology KW - Pulsed-field gel electrophoresis KW - Multidrug resistance KW - Q1 08625:Non-edible products KW - J 02400:Human Diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/968173472?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Genetic+diversity+and+antibiotic+resistance+in+Shigella+dysenteriae+and+Shigella+boydii+strains+isolated+from+children+aged+%26lt%3B5+years+in+Egypt&rft.au=El-Gendy%2C+A+M%3BMansour%2C+A%3BWeiner%2C+Ma%3BPimentel%2C+G%3BArmstrong%2C+A+W%3BYoung%2C+Syn%3BElsayed%2C+N%3BKlena%2C+J+D&rft.aulast=El-Gendy&rft.aufirst=A&rft.date=2012-02-01&rft.volume=140&rft.issue=2&rft.spage=299&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268811000525 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-01 N1 - Number of references - 3 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Epidemiology; Surveillance and enforcement; Genetic diversity; Antibiotics; Pathogens; Strains; Control resistance; Trimethoprim; Chloramphenicol; Diarrhea; Vomiting; Serotypes; Sulfamethoxazole; Ampicillin; Children; Tetracyclines; Fever; Pulsed-field gel electrophoresis; Multidrug resistance; Antibiotic resistance; Shigella boydii; Shigella dysenteriae; Egypt, Arab Rep. DO - http://dx.doi.org/10.1017/S0950268811000525 ER - TY - JOUR T1 - Global isoniazid resistance patterns in rifampin-resistant and rifampin-susceptible tuberculosis AN - 968170209; 16400888 AB - Following the World Health Organization's endorsement of the Xpert registered MTB/RIF assay, which rapidly and simultaneously diagnoses tuberculosis (TB) and detects resistance to rifampin (RMP), the question arises to what extent RMP resistance is an adequate marker for multi-drug-resistant TB (MDR-TB). A retrospective analysis of data from >81 countries and subnational settings demonstrated that >40% of RMP-resistant isolates from new TB cases did not display resistance to isoniazid (INH) in settings with relatively low MDR-TB prevalence (one third of all countries and subnational settings). Results indicated the need for INH susceptibility testing in addition to RMP susceptibility testing. JF - International Journal of Tuberculosis and Lung Disease AU - Smith, SE AU - Kurbatova, E V AU - Cavanaugh, J S AU - Cegielski, J P AD - Division of Tuberculosis Elimination, International Research and Programs Branch, Centers for Disease Control and Prevention, Mailstop E-10, 1600 Clifton Road, NE Atlanta, GA 30333, USA, pcegielski@cdc.gov Y1 - 2012/02// PY - 2012 DA - Feb 2012 SP - 203 EP - 205 PB - International Union Against Tuberculosis and Lung Disease VL - 16 IS - 2 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts KW - Rifampin KW - Data processing KW - Mycobacterium KW - Lung KW - Lung diseases KW - Tuberculosis KW - Isoniazid KW - H 0500:General KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/968170209?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Global+isoniazid+resistance+patterns+in+rifampin-resistant+and+rifampin-susceptible+tuberculosis&rft.au=Smith%2C+SE%3BKurbatova%2C+E+V%3BCavanaugh%2C+J+S%3BCegielski%2C+J+P&rft.aulast=Smith&rft.aufirst=SE&rft.date=2012-02-01&rft.volume=16&rft.issue=2&rft.spage=203&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Rifampin; Data processing; Lung diseases; Tuberculosis; Isoniazid; Lung; Mycobacterium ER - TY - JOUR T1 - Occupational Gradients in Smoking Behavior and Exposure to Workplace Environmental Tobacco Smoke The Multi-Ethnic Study of Atherosclerosis AN - 968166854; 16435501 AB - Objective: This study examines associations of occupation with smoking status, amount smoked among current and former smokers (number of cigarettes per day and lifetime cigarette consumption (pack-years)), and workplace exposure to environmental tobacco smoke (ETS) independent from income and education. Methods: This is a cross-sectional analysis of data from a community sample (n = 6355, age range: 45-84) using logistic and multinomial regression. All analyses were stratified by sex and adjusted for socio-demographic variables. Results: Male blue-collar and sales/office workers had higher odds of having consumed more than 20 pack-years of cigarettes than managers/professionals. For both male and female current or former smokers, exposure to workplace ETS was consistently and strongly associated with heavy smoking and greater pack-years. Conclusions: Blue-collar workplaces are associated with intense smoking and ETS exposure. Smoking must be addressed at both the individual and workplace levels especially in blue-collar workplaces. JF - Journal of Occupational and Environmental Medicine AU - Fujishiro, K AU - Stukovsky, KDH AU - Roux, AD AU - Landsbergis, P AU - Burchfiel, C AD - Division of Surveillance, Hazard Evaluation, and Field Studies, National Institute for Occupational Safety and Health, 4676 Columbia Pkwy (R-15), Cincinnati, OH 45226, USA, kfujishiro@cdc.gov Y1 - 2012/02// PY - 2012 DA - Feb 2012 SP - 136 EP - 145 VL - 54 IS - 2 SN - 1076-2752, 1076-2752 KW - Health & Safety Science Abstracts KW - Age KW - Behavior KW - Cigarettes KW - Education KW - Occupational exposure KW - Passive smoking KW - income KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/968166854?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Occupational+Gradients+in+Smoking+Behavior+and+Exposure+to+Workplace+Environmental+Tobacco+Smoke+The+Multi-Ethnic+Study+of+Atherosclerosis&rft.au=Fujishiro%2C+K%3BStukovsky%2C+KDH%3BRoux%2C+AD%3BLandsbergis%2C+P%3BBurchfiel%2C+C&rft.aulast=Fujishiro&rft.aufirst=K&rft.date=2012-02-01&rft.volume=54&rft.issue=2&rft.spage=136&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e318244501e LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-01 N1 - Last updated - 2013-05-06 N1 - SubjectsTermNotLitGenreText - Age; Education; Passive smoking; Behavior; Cigarettes; income; Occupational exposure DO - http://dx.doi.org/10.1097/JOM.0b013e318244501e ER - TY - JOUR T1 - Work Experiences of Latina Immigrants: A Qualitative Study AN - 923201110; 16220723 AB - Almost half of the Latino immigrants working in the United States are women. However, studies concerning the work experiences of Latinas are almost absent in the literature. This article reports the findings from a qualitative study using eight focus groups (n = 53) of Latina immigrant workers. The focus group transcripts were analyzed using the grounded theory approach in which themes emerge from iterative readings of the transcripts by a group of investigators. This study identified themes related to excessive workload, familiar work/unfamiliar hazards, cultural tensions, lack of health care, pregnancy, sexual harassment, and family obligations/expectations. The responses of the Latina workers in this study clearly indicated that they live within a complex web of stressors, both as workers and as women. The increased economic opportunities that come with immigration to the United States are accompanied by many opportunities for exploitation, especially if they are undocumented. It is hoped that the findings of this study will raise awareness regarding these issues and spur further work in this area. JF - Journal of Career Development AU - Eggerth, Donald E AU - DeLaney, Sheli C AU - Flynn, Michael A AU - Jacobson, CJeff AD - National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, OH, USA  , deggerth@cdc.gov Y1 - 2012/02// PY - 2012 DA - Feb 2012 SP - 13 EP - 30 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU United Kingdom VL - 39 IS - 1 SN - 0894-8453, 0894-8453 KW - Sustainability Science Abstracts KW - Immigration KW - immigrants KW - sexual harassment KW - working conditions KW - careers KW - USA KW - Health care KW - Economics KW - Ethnic groups KW - culture KW - M3 1010:Issues in Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/923201110?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Career+Development&rft.atitle=Work+Experiences+of+Latina+Immigrants%3A+A+Qualitative+Study&rft.au=Eggerth%2C+Donald+E%3BDeLaney%2C+Sheli+C%3BFlynn%2C+Michael+A%3BJacobson%2C+CJeff&rft.aulast=Eggerth&rft.aufirst=Donald&rft.date=2012-02-01&rft.volume=39&rft.issue=1&rft.spage=13&rft.isbn=&rft.btitle=&rft.title=Journal+of+Career+Development&rft.issn=08948453&rft_id=info:doi/10.1177%2F0894845311417130 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-02-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - careers; Immigration; Health care; immigrants; sexual harassment; Economics; working conditions; culture; Ethnic groups; USA DO - http://dx.doi.org/10.1177/0894845311417130 ER - TY - JOUR T1 - Lead poisoning in United States-bound refugee children: Thailand-Burma border, 2009. AN - 919953244; 22250021 AB - Elevated blood lead levels lead to permanent neurocognitive sequelae in children. Resettled refugee children in the United States are considered at high risk for elevated blood lead levels, but the prevalence of and risk factors for elevated blood lead levels before resettlement have not been described. Blood samples from children aged 6 months to 14 years from refugee camps in Thailand were tested for lead and hemoglobin. Sixty-seven children with elevated blood lead levels (venous ≥10 µg/dL) or undetectable (capillary <3.3 µg/dL) blood lead levels participated in a case-control study. Of 642 children, 33 (5.1%) had elevated blood lead levels. Children aged <2 years had the highest prevalence (14.5%). Among children aged <2 years included in a case-control study, elevated blood lead levels risk factors included hemoglobin <10 g/dL, exposure to car batteries, and taking traditional medicines. The prevalence of elevated blood lead levels among tested US-bound Burmese refugee children was higher than the current US prevalence, and was especially high among children <2 years old. Refugee children may arrive in the United States with elevated blood lead levels. A population-specific understanding of preexisting lead exposures can enhance postarrival lead-poisoning prevention efforts, based on Centers for Disease Control and Prevention recommendations for resettled refugee children, and can lead to remediation efforts overseas. JF - Pediatrics AU - Mitchell, Tarissa AU - Jentes, Emily AU - Ortega, Luis AU - Scalia Sucosky, Marissa AU - Jefferies, Taran AU - Bajcevic, Predrag AU - Parr, Valentina AU - Jones, Warren AU - Brown, Mary Jean AU - Painter, John AD - Division of Global Migration, Immigrant, Refugee, and Migrant Health Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA. tmitchell1@cdc.gov Y1 - 2012/02// PY - 2012 DA - February 2012 SP - e392 EP - e399 VL - 129 IS - 2 KW - Lead KW - 2P299V784P KW - Abridged Index Medicus KW - Index Medicus KW - United States KW - Nutritional Status KW - Anemia, Iron-Deficiency -- ethnology KW - Humans KW - Child KW - Lead -- blood KW - Child, Preschool KW - Infant KW - Cross-Sectional Studies KW - Thailand -- ethnology KW - Anemia, Iron-Deficiency -- epidemiology KW - Case-Control Studies KW - Anemia, Iron-Deficiency -- diagnosis KW - Adolescent KW - Myanmar -- ethnology KW - Male KW - Female KW - Lead Poisoning -- ethnology KW - Lead Poisoning -- epidemiology KW - Lead Poisoning -- diagnosis KW - Emigrants and Immigrants -- statistics & numerical data KW - Refugees -- statistics & numerical data UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/919953244?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Pediatrics&rft.atitle=Lead+poisoning+in+United+States-bound+refugee+children%3A+Thailand-Burma+border%2C+2009.&rft.au=Mitchell%2C+Tarissa%3BJentes%2C+Emily%3BOrtega%2C+Luis%3BScalia+Sucosky%2C+Marissa%3BJefferies%2C+Taran%3BBajcevic%2C+Predrag%3BParr%2C+Valentina%3BJones%2C+Warren%3BBrown%2C+Mary+Jean%3BPainter%2C+John&rft.aulast=Mitchell&rft.aufirst=Tarissa&rft.date=2012-02-01&rft.volume=129&rft.issue=2&rft.spage=e392&rft.isbn=&rft.btitle=&rft.title=Pediatrics&rft.issn=1098-4275&rft_id=info:doi/10.1542%2Fpeds.2011-1218 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-03-27 N1 - Date created - 2012-02-03 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1542/peds.2011-1218 ER - TY - JOUR T1 - Laboratory equipment maintenance: A critical bottleneck for strengthening health systems in sub-Saharan Africa? AN - 1728649656; 2011-215459 AB - Properly functioning laboratory equipment is a critical component for strengthening health systems in developing countries. The laboratory can be an entry point to improve population health and care of individuals for targeted diseases -- prevention, care, and treatment of TB, HIV/AIDS, and malaria, plus maternal and neonatal health -- as well as those lacking specific attention and funding. We review the benefits and persistent challenges associated with sustaining laboratory equipment maintenance. We propose equipment management policies as well as a comprehensive equipment maintenance strategy that would involve equipment manufacturers and strengthen local capacity through pre-service training of biomedical engineers. Strong country leadership and commitment are needed to assure development and sustained implementation of policies and strategies for standardization of equipment, and regulation of its procurement, donation, disposal, and replacement. Adapted from the source document. JF - Journal of Public Health Policy AU - Fonjungo, Peter N AU - Kebede, Yenew AU - Messele, Tsehaynesh AU - Ayana, Gonfa AU - Tibesso, Gudeta AU - Abebe, Almaz AU - Nkengasong, John N AU - Kenyon, Thomas AD - Division of Global HIV/AIDS, Center for Global Health, Centers for Disease Control and Prevention, PO Box 1014 Entoto Road, Addis Ababa, Ethiopia fonjungop@et.cdc.gov Y1 - 2012/02// PY - 2012 DA - February 2012 SP - 34 EP - 45 PB - Palgrave Macmillan, Basingstoke UK VL - 33 IS - 1 SN - 0197-5897, 0197-5897 KW - laboratory equipment, maintenance, developing countries KW - Engineers KW - Equipment KW - Purchasing KW - Human immunodeficiency virus KW - Laboratories KW - Care and treatment KW - Africa KW - Regulation KW - Leadership KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1728649656?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Public+Health+Policy&rft.atitle=Laboratory+equipment+maintenance%3A+A+critical+bottleneck+for+strengthening+health+systems+in+sub-Saharan+Africa%3F&rft.au=Fonjungo%2C+Peter+N%3BKebede%2C+Yenew%3BMessele%2C+Tsehaynesh%3BAyana%2C+Gonfa%3BTibesso%2C+Gudeta%3BAbebe%2C+Almaz%3BNkengasong%2C+John+N%3BKenyon%2C+Thomas&rft.aulast=Fonjungo&rft.aufirst=Peter&rft.date=2012-02-01&rft.volume=33&rft.issue=1&rft.spage=34&rft.isbn=&rft.btitle=&rft.title=Journal+of+Public+Health+Policy&rft.issn=01975897&rft_id=info:doi/10.1057%2Fjphp.2011.57 LA - English DB - PAIS Index N1 - Date revised - 2015-11-01 N1 - Last updated - 2016-09-28 N1 - CODEN - JPPODK N1 - SubjectsTermNotLitGenreText - Equipment; Laboratories; Leadership; Human immunodeficiency virus; Regulation; Africa; Purchasing; Care and treatment; Engineers DO - http://dx.doi.org/10.1057/jphp.2011.57 ER - TY - JOUR T1 - Local Innate Immune Responses and Influenza Virus Transmission and Virulence in Ferrets AN - 1642613021; 20933605 AB - Host innate immunity is the first line of defense against invading pathogens, including influenza viruses. Ferrets are well recognized as the best model of influenza virus pathogenesis and transmission, but little is known about the innate immune response of ferrets after infection with this virus. The goal of this study was to investigate the contribution of localized host responses to influenza virus pathogenicity and transmissibility in this model by measuring the level of messenger RNA expression of 12 cytokines and chemokines in the upper and lower respiratory tracts of ferrets infected with H5N1, H1N1, or H3N2 influenza viruses that exhibit diverse virulence and transmissibility in ferrets. We found a strong temporal correlation between inflammatory mediators and the kinetics and frequency of transmission, clinical signs associated with transmission, peak virus shedding, and virulence. Our findings point to a link between localized innate immunity and influenza virus transmission and disease progression. JF - Journal of Infectious Diseases AU - Maines, Taronna R AU - Belser, Jessica A AU - Gustin, Kortney M AU - van Hoeven, Neal AU - Zeng, Hui AU - Svitek, Nicholas AU - von Messling, Veronika AU - Katz, Jacqueline M AU - Tumpey, Terrence M AD - Influenza Division, National Center for Immunization and Respiratory Disease, Centers for Disease Control and Prevention, Atlanta, Georgia, ttumpey@cdc.gov Y1 - 2012/02/01/ PY - 2012 DA - 2012 Feb 01 SP - 474 EP - 485 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 205 IS - 3 SN - 0022-1899, 0022-1899 KW - Immunology Abstracts; Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Chemokines KW - Viruses KW - Infection KW - Models KW - Disease transmission KW - Gene expression KW - Virulence KW - Influenza KW - Mustela KW - Infectious diseases KW - Pathogenicity KW - Cytokines KW - Respiratory tract KW - Pathogens KW - Immunity KW - Inflammation KW - Influenza virus KW - Kinetics KW - Immune response KW - V 22350:Immunology KW - H 1000:Occupational Safety and Health KW - F 06910:Microorganisms & Parasites UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1642613021?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Local+Innate+Immune+Responses+and+Influenza+Virus+Transmission+and+Virulence+in+Ferrets&rft.au=Maines%2C+Taronna+R%3BBelser%2C+Jessica+A%3BGustin%2C+Kortney+M%3Bvan+Hoeven%2C+Neal%3BZeng%2C+Hui%3BSvitek%2C+Nicholas%3Bvon+Messling%2C+Veronika%3BKatz%2C+Jacqueline+M%3BTumpey%2C+Terrence+M&rft.aulast=Maines&rft.aufirst=Taronna&rft.date=2012-02-01&rft.volume=205&rft.issue=3&rft.spage=474&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjir768 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Chemokines; Immunity; Pathogens; Infection; Disease transmission; Models; Inflammation; Influenza; Virulence; Gene expression; Pathogenicity; Kinetics; Cytokines; Immune response; Respiratory tract; Infectious diseases; Viruses; Influenza virus; Mustela DO - http://dx.doi.org/10.1093/infdis/jir768 ER - TY - CPAPER T1 - Hospitalization Costs of Stroke among Adults 18-64 Years in the United States T2 - 2012 International Stroke Conference AN - 1313087032; 6186409 JF - 2012 International Stroke Conference AU - Wang, Guijing AU - Zhang, Zefeng AU - Ayala, Carma AU - Dunet, Diane AU - Fang, Jing AU - George, Mary Y1 - 2012/02/01/ PY - 2012 DA - 2012 Feb 01 KW - USA KW - Stroke UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313087032?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2012+International+Stroke+Conference&rft.atitle=Hospitalization+Costs+of+Stroke+among+Adults+18-64+Years+in+the+United+States&rft.au=Wang%2C+Guijing%3BZhang%2C+Zefeng%3BAyala%2C+Carma%3BDunet%2C+Diane%3BFang%2C+Jing%3BGeorge%2C+Mary&rft.aulast=Wang&rft.aufirst=Guijing&rft.date=2012-02-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2012+International+Stroke+Conference&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/Browse.aspx LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - JOUR T1 - Manganese accumulation in nail clippings as a biomarker of welding fume exposure and neurotoxicity AN - 920793979; 16165877 AB - Occupational exposure to welding fumes (WF) is thought to cause Parkinson's disease (PD)-like neurological dysfunction. An apprehension that WF may accelerate the onset of PD also exists. Identifying reliable biomarkers of exposure and neurotoxicity are therefore critical for biomonitoring and neurological risk characterization of WF exposure. Manganese (Mn) in welding consumables is considered the causative factor for the neurological deficits seen in welders. Hence, we sought to determine if Mn accumulation in blood or nail clippings can be a marker for adverse exposure and neurotoxicity. To model this, rats were exposed by intratracheal instillation to dissolved or suspended fume components collected from gas metal arc-mild steel (GMA-MS) or manual metal arc-hard surfacing (MMA-HS) welding. Trace element analysis revealed selective Mn accumulation in dopaminergic brain areas, striatum (STR) and midbrain (MB), following exposure to the two fumes. This caused dopaminergic abnormality as evidenced by loss of striatal tyrosine hydroxylase (Th; 25-32% decrease) and Parkinson disease (autosomal recessive, early onset) 7 (Park7; 25-46% decrease) proteins. While blood Mn was not detectable, Mn levels in nails strongly correlated with the pattern of Mn accumulation in the striatum (R2=0.9386) and midbrain (R2=0.9332). Exposure to manganese chloride (MnCl2) caused similar Mn accumulation in STR, MB and nail. Our findings suggest that nail Mn has the potential to be a sensitive and reliable biomarker for long-term Mn exposure and associated neurotoxicity. The non-invasive means by which nail clippings can be collected, stored, and transported with relative ease, make it an attractive surrogate for biomonitoring WF exposures in occupational settings. JF - Toxicology AU - Sriram, Krishnan AU - Lin, Gary X AU - Jefferson, Amy M AU - Roberts, Jenny R AU - Andrews, Ronnee N AU - Kashon, Michael L AU - Antonini, James M AD - Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505, USA, kos4@cdc.gov Y1 - 2012/01/27/ PY - 2012 DA - 2012 Jan 27 SP - 73 EP - 82 PB - Elsevier B.V., P.O. Box 85 Limerick Ireland VL - 291 IS - 1-3 SN - 0300-483X, 0300-483X KW - CSA Neurosciences Abstracts; Health & Safety Science Abstracts; Environment Abstracts; Toxicology Abstracts KW - Neurological diseases KW - Heavy metals KW - Parkinson's disease KW - Chlorides KW - Chloride KW - Trace elements KW - Mesencephalon KW - Dopamine KW - Neostriatum KW - Welding KW - biomonitoring KW - Manganese KW - Occupational exposure KW - Bioindicators KW - Metals KW - Fumes KW - Brain KW - biomarkers KW - Neurodegenerative diseases KW - Blood KW - Movement disorders KW - Neurotoxicity KW - Tyrosine 3-monooxygenase KW - N3 11028:Neuropharmacology & toxicology KW - H 1000:Occupational Safety and Health KW - X 24360:Metals KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/920793979?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology&rft.atitle=Manganese+accumulation+in+nail+clippings+as+a+biomarker+of+welding+fume+exposure+and+neurotoxicity&rft.au=Sriram%2C+Krishnan%3BLin%2C+Gary+X%3BJefferson%2C+Amy+M%3BRoberts%2C+Jenny+R%3BAndrews%2C+Ronnee+N%3BKashon%2C+Michael+L%3BAntonini%2C+James+M&rft.aulast=Sriram&rft.aufirst=Krishnan&rft.date=2012-01-27&rft.volume=291&rft.issue=1-3&rft.spage=73&rft.isbn=&rft.btitle=&rft.title=Toxicology&rft.issn=0300483X&rft_id=info:doi/10.1016%2Fj.tox.2011.10.021 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-02-01 N1 - Number of references - 2 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Neurological diseases; Fumes; Heavy metals; Parkinson's disease; Chloride; biomarkers; Trace elements; Blood; Neurodegenerative diseases; Mesencephalon; Movement disorders; Dopamine; Neurotoxicity; Neostriatum; biomonitoring; Welding; Tyrosine 3-monooxygenase; Manganese; Occupational exposure; Bioindicators; Metals; Chlorides; Brain DO - http://dx.doi.org/10.1016/j.tox.2011.10.021 ER - TY - JOUR T1 - Direct costs of a single case of refugee-imported measles in Kentucky AN - 918055475; 16186374 AB - Background: Refugees are highly vulnerable populations with limited access to health care services. The United States accepts 50,000-75,000 refugees for resettlement annually. Despite residing in camps and other locations where vaccine-preventable disease outbreaks, such as measles, occur frequently, refugees are not required to have any vaccinations before they arrive in the United States. Purpose: We estimated the medical and public-health response costs of a case of measles imported into Kentucky by a refugee. Methods: The Kentucky Refugee Health Coordinator recorded the time and labor of local, state, and some federal personnel involved in caring for the refugee and implementing the public health response activities. Secondary sources were used to estimate the labor and medical care costs of the event. Results: The total costs to conduct the response to the disease event were approximately $25,000. All costs were incurred by government, either public health department or federal, because refugee health costs are paid by the federal government and the event response costs are covered by the public health department. Conclusion: A potentially preventable case of measles that was imported into the United States cost approximately $25,000 for the public health response. Recommendation: To maintain the elimination of measles transmission in the United States, U.S.-bound refugees should be vaccinated overseas. A refugee vaccination program administered during the overseas health assessment has the potential to reduce the risk of importation of measles and other vaccine-preventable disease and would eliminate costs associated with public health response to imported cases and outbreaks. JF - Vaccine AU - Coleman, Margaret S AU - Garbat-Welch, Luta AU - Burke, Heather AU - Weinberg, Michelle AU - Humbaugh, Kraig AU - Tindall, Alicia AU - Cambron, Janie AD - Centers for Disease Control and Prevention, Division of Global Migration and Quarantine, MS E-03, 1600 Clifton Road, Atlanta, GA 30333, United States, mcoleman@cdc.gov Y1 - 2012/01/05/ PY - 2012 DA - 2012 Jan 05 SP - 317 EP - 321 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 30 IS - 2 SN - 0264-410X, 0264-410X KW - Risk Abstracts; Sustainability Science Abstracts; Virology & AIDS Abstracts; Health & Safety Science Abstracts; Immunology Abstracts KW - Cyclic AMP KW - Disease transmission KW - Health care KW - Importation KW - Measles KW - Personnel KW - Public health KW - Refugees KW - Risk reduction KW - Vaccination KW - Vulnerability KW - outbreaks KW - refugees KW - risk reduction KW - vaccines KW - vulnerability KW - USA, Kentucky KW - F 06905:Vaccines KW - M3 1010:Issues in Sustainable Development KW - R2 23060:Medical and environmental health KW - H 4000:Food and Drugs KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/918055475?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Direct+costs+of+a+single+case+of+refugee-imported+measles+in+Kentucky&rft.au=Coleman%2C+Margaret+S%3BGarbat-Welch%2C+Luta%3BBurke%2C+Heather%3BWeinberg%2C+Michelle%3BHumbaugh%2C+Kraig%3BTindall%2C+Alicia%3BCambron%2C+Janie&rft.aulast=Coleman&rft.aufirst=Margaret&rft.date=2012-01-05&rft.volume=30&rft.issue=2&rft.spage=317&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/10.1016%2Fj.vaccine.2011.10.091 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-01-01 N1 - Last updated - 2012-06-29 N1 - SubjectsTermNotLitGenreText - Personnel; Measles; Cyclic AMP; Importation; Vaccination; Disease transmission; Public health; refugees; risk reduction; vaccines; Health care; vulnerability; Vulnerability; Risk reduction; outbreaks; Refugees; USA, Kentucky DO - http://dx.doi.org/10.1016/j.vaccine.2011.10.091 ER - TY - JOUR T1 - Domestic Dogs (Canis familiaris) as Reservoir Hosts for Rickettsia conorii AN - 968172106; 16448428 AB - Rickettsia conorii is the causative agent of Mediterranean spotted fever (MSF) and Israeli spotted fever (ISF) transmitted by the brown dog tick Rhipicephalus sanguineus. In areas where MSF or ISF are prevalent, dogs have high prevalence of R. conorii -neutralizing antibodies. However, the true role of dogs in the persistence of the R. conorii transmission cycle is unknown, and their reservoir competence for this pathogen has remained untested. We assessed the ability of dogs infected with R. conorii to transmit the pathogen to previously uninfected Rh. sanguineus ticks. Dogs were infected either via needle-inoculation of cultured rickettsiae or naturally via infected tick bite. Dogs were monitored for clinical signs of infection, for rickettsemia by PCR, and for seroconversion and were subjected to infestation with uninfected ticks at different time points. Rh. sanguineus larvae and nymphs successfully acquired the agent from both needle-inoculated and tick-infected dogs and transmitted it transtadially. Tick-infected dogs remained infectious to ticks for at least a month postinfection. The molted ticks were, in turn, infectious to naive dogs. These results demonstrate that dogs are capable of acquiring R. conorii from infected Rh. sanguineus ticks and transmitting infection to cohorts of uninfected ticks, thus confirming for the first time that dogs are indeed competent reservoirs for R. conorii. In addition, dogs with different genetic backgrounds appear to differ in their susceptibility to R. conorii infection. JF - Vector Borne and Zoonotic Diseases AU - Levin, M L AU - Killmaster, L F AU - Zemtsova, GE AD - Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, 1600 Clifton Road, MS G-13, Atlanta, GA 30333, USA, mlevin@cdc.gov Y1 - 2012/01// PY - 2012 DA - Jan 2012 SP - 28 EP - 33 VL - 12 IS - 1 SN - 1530-3667, 1530-3667 KW - Entomology Abstracts; Microbiology Abstracts B: Bacteriology KW - Antibodies KW - Bites KW - Disease transmission KW - Infection KW - Infestation KW - Mediterranean spotted fever KW - Pathogens KW - Polymerase chain reaction KW - Seroconversion KW - Spotted fevers KW - Vectors KW - Canis familiaris KW - Ixodidae KW - Rickettsia conorii KW - Rhipicephalus sanguineus KW - J 02410:Animal Diseases KW - Z 05350:Medical, Veterinary, and Agricultural Entomology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/968172106?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vector+Borne+and+Zoonotic+Diseases&rft.atitle=Domestic+Dogs+%28Canis+familiaris%29+as+Reservoir+Hosts+for+Rickettsia+conorii&rft.au=Levin%2C+M+L%3BKillmaster%2C+L+F%3BZemtsova%2C+GE&rft.aulast=Levin&rft.aufirst=M&rft.date=2012-01-01&rft.volume=12&rft.issue=1&rft.spage=28&rft.isbn=&rft.btitle=&rft.title=Vector+Borne+and+Zoonotic+Diseases&rft.issn=15303667&rft_id=info:doi/10.1089%2Fvbz.2011.0684 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-01 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - Infestation; Antibodies; Spotted fevers; Bites; Polymerase chain reaction; Seroconversion; Vectors; Pathogens; Infection; Mediterranean spotted fever; Disease transmission; Canis familiaris; Ixodidae; Rickettsia conorii; Rhipicephalus sanguineus DO - http://dx.doi.org/10.1089/vbz.2011.0684 ER - TY - JOUR T1 - Evaluating portable infrared spectrometers for measuring the silica content of coal dust AN - 954647774; 16404346 AB - Miners face a variety of respiratory hazards while on the job, including exposure to silica dust which can lead to silicosis, a potentially fatal lung disease. Currently, field-collected filter samples of silica are sent for laboratory analysis and the results take weeks to be reported. Since the mining workplace is constantly moving into new and often different geological strata with changing silica levels, more timely data on silica levels in mining workplaces could help reduce exposures. Improvements in infrared (IR) spectroscopy open the prospect for end-of-shift silica measurements at mine sites. Two field-portable IR spectrometers were evaluated for their ability to quantify the mass of silica on filter samples loaded with known amounts of either silica or silica-bearing coal dust (silica content ranging from 10-200 mu g/filter). Analyses included a scheme to correct for the presence of kaolin, which is a confounder for IR analysis of silica. IR measurements of the samples were compared to parallel measurements derived using the laboratory-based U.S. Mine Safety and Health Administration P7 analytical method. Linear correlations between Fourier transform infrared (FTIR) and P7 data yielded slopes in the range of 0.90-0.97 with minimal bias. Data from a variable filter array spectrometer did not correlate as well, mainly due to poor wavelength resolution compared to the FTIR instrument. This work has shown that FTIR spectrometry has the potential to reasonably estimate the silica exposure of miners if employed in an end-of-shift method. JF - Journal of Environmental Monitoring AU - Miller, AL AU - Drake, P L AU - Murphy, N C AU - Noll, J D AU - Volkwein, J C AD - National Institute for Occupational Safety and Health, 315 E. Montgomery Ave, Spokane, WA, 99207, USA, ALMiller@cdc.gov Y1 - 2012/01// PY - 2012 DA - January 2012 SP - 48 EP - 55 VL - 14 IS - 1 SN - 1464-0325, 1464-0325 KW - Environment Abstracts; Health & Safety Science Abstracts; Pollution Abstracts KW - Filters KW - USA KW - Fourier transforms KW - Safety regulations KW - silica KW - Occupational safety KW - Coal KW - Mining KW - Dust KW - Spectrometry KW - P 0000:AIR POLLUTION KW - H 1000:Occupational Safety and Health KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/954647774?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+Monitoring&rft.atitle=Evaluating+portable+infrared+spectrometers+for+measuring+the+silica+content+of+coal+dust&rft.au=Miller%2C+AL%3BDrake%2C+P+L%3BMurphy%2C+N+C%3BNoll%2C+J+D%3BVolkwein%2C+J+C&rft.aulast=Miller&rft.aufirst=AL&rft.date=2012-01-01&rft.volume=14&rft.issue=1&rft.spage=48&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+Monitoring&rft.issn=14640325&rft_id=info:doi/10.1039%2Fc1em10678c LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2016-08-03 N1 - SubjectsTermNotLitGenreText - Filters; Safety regulations; Fourier transforms; silica; Occupational safety; Mining; Coal; Dust; Spectrometry; USA DO - http://dx.doi.org/10.1039/c1em10678c ER - TY - JOUR T1 - Occupational Injuries, Illnesses, and Fatalities Among Workers in the Services Sector Industries 2003 to 2007 AN - 926891586; 16292450 AB - Objective: Provide descriptive statistics and discuss priorities for injury and fatality risks among services sector workers. Methods: Bureau of Labor Statistics Survey of Occupational Injuries and Illnesses and Census of Fatal Occupational Injuries data for 2003 to 2007 were analyzed to identify occupational injury and fatality risks for services sector industry groups. Results: Many services sector industry groups experienced, on average, greater than one occupational fatality per week, and survey of occupational injuries and illnesses days-away-from-work rates in excess of those for all US workers. Overall, transportation incidents and homicides are leading factors contributing to fatalities. Conclusions: These results indicate the need for adoption of safety and health prevention practices in numerous industry groups. For groups that experience elevated injury and fatality rates, priorities for research and intervention can be identified through these data. JF - Journal of Occupational and Environmental Medicine AU - Utterback, D F AU - Charles, LE AU - Schnorr, T M AU - Tiesman, H M AU - Storey, E AU - Vossenas, P AD - National Institute for Occupational Safety and Health, 4676 Columbia Parkway, Cincinnati, OH 45226, USA, dutterback@cdc.gov Y1 - 2012/01// PY - 2012 DA - Jan 2012 SP - 31 EP - 41 VL - 54 IS - 1 SN - 1076-2752, 1076-2752 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Injuries KW - Mortality KW - Occupational safety KW - Transportation KW - census KW - homicide KW - intervention KW - prevention KW - H 1000:Occupational Safety and Health KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/926891586?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Occupational+Injuries%2C+Illnesses%2C+and+Fatalities+Among+Workers+in+the+Services+Sector+Industries+2003+to+2007&rft.au=Utterback%2C+D+F%3BCharles%2C+LE%3BSchnorr%2C+T+M%3BTiesman%2C+H+M%3BStorey%2C+E%3BVossenas%2C+P&rft.aulast=Utterback&rft.aufirst=D&rft.date=2012-01-01&rft.volume=54&rft.issue=1&rft.spage=31&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e3182398e36 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2013-05-06 N1 - SubjectsTermNotLitGenreText - census; Mortality; homicide; Transportation; Injuries; intervention; Occupational safety; prevention DO - http://dx.doi.org/10.1097/JOM.0b013e3182398e36 ER - TY - JOUR T1 - Higher incidence of clear cell adenocarcinoma of the cervix and vagina among women born between 1947 and 1971 in the United States AN - 926881525; 16343303 AB - Although the association between in utero exposure to diethylstilbestrol (DES) and clear cell adenocarcinoma of the cervix and vagina (CCA) was first reported among young women, subsequent case reports and cohort studies suggest that an elevated risk for CCA may persist with age. Data from the National Program of Cancer Registries (NPCR) and the Surveillance, Epidemiology and End Results (SEER) Program were used to construct indirect standardized incidence ratios (SIR) comparing CCA risk among women born during the exposure period 1947 through 1971, when DES was prescribed to pregnant women, to the relevant time period for nonexposed women born before or after DES exposure period. CCA incidence among the women born before the DES exposure period (ages 30-54 at diagnosis of CAA) or after the DES exposure period (ages 15-29 at diagnosis) were used to calculate the expected rates for women born during the DES exposure period. Among women aged 15-29 years, CCA risk increased with age and peaked in the 25-29 year age group, but the risk estimates were unstable (SIR = 6.06; 95% CI: 0.97, -251.07, SEER data). Among women aged 40-54 years, CCA risk was greatest in the 40-44 year age group (SIR = 4.55; 95% CI: 1.11, 40.19, SEER data and SIR = 3.94; 95% CI: 1.06, 33.01, NPCR/SEER data) and remained significantly elevated throughout this age group in the combined data set. Risk was not elevated among women aged 30-39 years. The observed risk of CCA, if causally related to DES exposure, reflects a persistent health impact from in utero exposure that is widespread in the general population. When assessing a woman's cancer risks, whether her mother took DES while pregnant may still be a relevant aspect of the medical history for women born during the period of DES use in pregnancy. JF - Cancer Causes & Control AU - Smith, Emily K AU - White, Mary C AU - Weir, Hannah K AU - Peipins, Lucy A AU - Thompson, Trevor D AD - Epidemiology and Applied Research Branch, Division of Cancer Prevention and Control, Centers for Disease Prevention and Control, 4770 Buford Highway, NE, Mailstop K55, Atlanta, GA, 30341-3717, USA, mxw5@cdc.gov Y1 - 2012/01// PY - 2012 DA - Jan 2012 SP - 207 EP - 211 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 23 IS - 1 SN - 0957-5243, 0957-5243 KW - Health & Safety Science Abstracts; Risk Abstracts KW - Historical account KW - USA KW - Age KW - Prenatal experience KW - Standards KW - Females KW - Cancer KW - Pregnancy KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/926881525?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cancer+Causes+%26+Control&rft.atitle=Higher+incidence+of+clear+cell+adenocarcinoma+of+the+cervix+and+vagina+among+women+born+between+1947+and+1971+in+the+United+States&rft.au=Smith%2C+Emily+K%3BWhite%2C+Mary+C%3BWeir%2C+Hannah+K%3BPeipins%2C+Lucy+A%3BThompson%2C+Trevor+D&rft.aulast=Smith&rft.aufirst=Emily&rft.date=2012-01-01&rft.volume=23&rft.issue=1&rft.spage=207&rft.isbn=&rft.btitle=&rft.title=Cancer+Causes+%26+Control&rft.issn=09575243&rft_id=info:doi/10.1007%2Fs10552-011-9855-z LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2014-05-29 N1 - SubjectsTermNotLitGenreText - Historical account; Age; Prenatal experience; Standards; Females; Cancer; Pregnancy; USA DO - http://dx.doi.org/10.1007/s10552-011-9855-z ER - TY - JOUR T1 - Association Between Cumulative Fiber Exposure and Respiratory Outcomes Among Libby Vermiculite Workers AN - 923199231; 16292453 AB - Objective: To examine the association between cumulative fiber exposure and health outcomes in workers (n = 336) with Libby amphibole exposure. Methods: Exposure-response relationships were explored by the use of logistic regression, with cumulative fiber exposure modeled in categories and as a continuous variable. Results: The use of spline functions with lifetime cumulative fiber exposure as a continuous variable showed that the odds of localized pleural thickening were significantly elevated at less than 1 f/cc-y. Odds of parenchymal abnormalities, restrictive spirometry, and chronic bronchitis were also significantly elevated at 108, 166, and 24 f/cc-y, respectively. Conclusions: The odds of several pulmonary health outcomes are correlated with cumulative exposure to Libby amphibole. That relatively low-lifetime cumulative exposures are associated with localized pleural thickening has implications for the non-cancer-risk assessment for Libby amphibole. JF - Journal of Occupational and Environmental Medicine AU - Larson, T C AU - Antao, V C AU - Bove, F J AU - Cusack, C AD - Division of Health Studies, Agency for Toxic Substances and Disease Registry, 4770 Buford Hwy NE, MS F57, Atlanta, GA 30341, USA, th13@cdc.gov Y1 - 2012/01// PY - 2012 DA - Jan 2012 SP - 56 EP - 63 VL - 54 IS - 1 SN - 1076-2752, 1076-2752 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Dose-response effects KW - Fibers KW - Occupational exposure KW - R2 23080:Industrial and labor KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/923199231?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Association+Between+Cumulative+Fiber+Exposure+and+Respiratory+Outcomes+Among+Libby+Vermiculite+Workers&rft.au=Larson%2C+T+C%3BAntao%2C+V+C%3BBove%2C+F+J%3BCusack%2C+C&rft.aulast=Larson&rft.aufirst=T&rft.date=2012-01-01&rft.volume=54&rft.issue=1&rft.spage=56&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e31823c141c LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-02-01 N1 - Last updated - 2013-05-06 N1 - SubjectsTermNotLitGenreText - Fibers; Dose-response effects; Occupational exposure DO - http://dx.doi.org/10.1097/JOM.0b013e31823c141c ER - TY - JOUR T1 - Association of overtime work with cellular immune markers among healthy daytime white-collar employees AN - 920803642; 16281334 AB - Objective Even though overtime work has been suspected to be a risk factor for ill health, little research has been done to determine the underlying immunological mechanisms. This study investigated the association between overtime work and cellular immunity among Japanese white-collar workers. Methods A total of 306 healthy, full-time, non-shift, daytime employees (165 men and 141 women), aged 22-69 (mean 36) years, provided a blood sample for the measurement of circulating immune [natural killer (NK), B, and T] cells and NK cell cytotoxicity (NKCC) and completed a questionnaire survey including overtime/month. Blood samples were collected between 09.00-11.00 hours during working days and participants completed the questionnaire within the two weeks prior to the blood sampling. Stepwise linear regression analyses controlling for confounders were carried out to examine the relationship between overtime work and immune markers. Results Overtime work was mainly related to short sleep duration, increased weight, and reduced job satisfaction, and it was more prevalent among men than women and among younger and married employees. Amount of overtime was inversely associated with NK (CD3-CD56+) cell counts (ss=-0.145; P =0.032) but was not associated with NKCC, NKCC/NK cell ratio, or T or B cells. Conclusions The NK cell is a lymphocyte that possesses killer activity against tumor and virus-infected cells and constitutes a major component of the innate immune system. A decrease of NK cell counts from overtime work suggests a dampened innate immune defense. However, the finding needs to be further validated with a well-designed study using objective overtime measures. JF - Scandinavian Journal of Work, Environment & Health AU - Nakata, A AU - Takahashi, M AU - Irie, M AD - Division of Applied Research and Technology, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, MS-C24, Cincinnati, OH 45226, USA, cji5@cdc.gov Y1 - 2012/01// PY - 2012 DA - Jan 2012 SP - 56 EP - 64 VL - 38 IS - 1 SN - 0355-3140, 0355-3140 KW - Immunology Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - Inventories KW - immune system KW - Lymphocytes B KW - Immune system KW - Natural killer cells KW - tumors KW - Lymphocytes KW - Tumors KW - Cytotoxicity KW - Daytime KW - Immunity (cell-mediated) KW - Sleep KW - Risk factors KW - Lymphocytes T KW - Regression analysis KW - Sampling KW - Japan KW - H 1000:Occupational Safety and Health KW - R2 23060:Medical and environmental health KW - F 06910:Microorganisms & Parasites UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/920803642?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Scandinavian+Journal+of+Work%2C+Environment+%26+Health&rft.atitle=Association+of+overtime+work+with+cellular+immune+markers+among+healthy+daytime+white-collar+employees&rft.au=Nakata%2C+A%3BTakahashi%2C+M%3BIrie%2C+M&rft.aulast=Nakata&rft.aufirst=A&rft.date=2012-01-01&rft.volume=38&rft.issue=1&rft.spage=56&rft.isbn=&rft.btitle=&rft.title=Scandinavian+Journal+of+Work%2C+Environment+%26+Health&rft.issn=03553140&rft_id=info:doi/10.5271%2Fsjweh.3183 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-02-01 N1 - Last updated - 2013-08-23 N1 - SubjectsTermNotLitGenreText - Inventories; Lymphocytes B; Immune system; Natural killer cells; Tumors; Cytotoxicity; Daytime; Immunity (cell-mediated); Risk factors; Sleep; Regression analysis; Lymphocytes T; Sampling; immune system; tumors; Lymphocytes; Japan DO - http://dx.doi.org/10.5271/sjweh.3183 ER - TY - JOUR T1 - Improvement of a mine fire simulation program - incorporation of smoke rollback into MFIRE 3.0 AN - 920792575; 16209844 AB - Smoke rollback is a dangerous threat to miners and firefighters in an underground mine fire. The ability to predict smoke rollback can greatly improve the chances for safe miner evacuation and mine fire control and firefighting. A modified semi-empirical equation based on large-scale experiments conducted by the National Institute for Occupational Safety and Health (NIOSH) was developed to quantify smoke rollback during an underground mine fire. The equation was incorporated into a mine fire simulation program (MFIRE 3.0) to allow the user to predict the occurrence of smoke rollback and calculate the smoke rollback distance. This article describes the development of the equation and compares the experimental results with those predicted by MFIRE 3.0. The results indicate that the improved MFIRE 3.0 is capable of determining smoke rollback in a fire entry, not only to provide early warning for smoke rollback but also to verify the effectiveness of smoke rollback control efforts. JF - Journal of Fire Sciences AU - Zhou, Lihong AU - Smith, Alex C AD - Office of Mine Safety and Health Research, National Institute for Occupational Safety and Health, Pittsburgh, PA, itn2@cdc.gov Y1 - 2012/01// PY - 2012 DA - Jan 2012 SP - 29 EP - 39 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU United Kingdom VL - 30 IS - 1 SN - 0734-9041, 0734-9041 KW - Health & Safety Science Abstracts KW - coal mine fire KW - mine fire simulation KW - smoke rollback KW - Smoke KW - Fires KW - firefighter services KW - Occupational safety KW - Simulation KW - Mining KW - Mines KW - evacuation KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/920792575?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Fire+Sciences&rft.atitle=Improvement+of+a+mine+fire+simulation+program+-+incorporation+of+smoke+rollback+into+MFIRE+3.0&rft.au=Zhou%2C+Lihong%3BSmith%2C+Alex+C&rft.aulast=Zhou&rft.aufirst=Lihong&rft.date=2012-01-01&rft.volume=30&rft.issue=1&rft.spage=29&rft.isbn=&rft.btitle=&rft.title=Journal+of+Fire+Sciences&rft.issn=07349041&rft_id=info:doi/10.1177%2F0734904111418483 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-02-01 N1 - Number of references - 17 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Smoke; Fires; firefighter services; Occupational safety; Simulation; Mining; Mines; evacuation DO - http://dx.doi.org/10.1177/0734904111418483 ER - TY - JOUR T1 - Hollow-fiber ultrafiltration for simultaneous recovery of viruses, bacteria and parasites from reclaimed water AN - 918066535; 16143866 AB - Hollow-fiber ultrafiltration (UF) is a technique that has been reported to be effective for recovering a diverse array of microbes from water, and may also be potentially useful for microbial monitoring of effluent from water reclamation facilities. However, few data are available to indicate the potential limitations and efficacy of the UF technique for treated wastewater. In this study, recovery efficiencies were determined for various options available for performing the tangential-flow UF technique, including hollow-fiber ultrafilter (i.e., dialyzer) type, ultrafilter pre-treatment (i.e., blocking), and elution. MS2 and Phi X174 bacteriophages, Clostridium perfringens spores, Escherichia coli, and Cryptosporidium parvum oocysts were seeded into 10-L reclaimed water samples to evaluate UF options. Then a single UF protocol was established and studied using seeded and non-seeded 100-L samples from two water reclamation facilities in Georgia, USA. Baxter Exeltra Plus 210 and Fresenius F200NR dialyzers were found to provide significantly higher microbial recovery than Minntech HPH 1400 hemoconcentrators. The selected final UF method incorporated use of a non-blocked ultrafilter for UF followed by elution using a surfactant-based solution. For 10-L samples, this method achieved recovery efficiencies of greater than 50% recovery of seeded viruses, bacteria, and parasites. There was no significant difference in overall microbial recovery efficiency when the method was applied to 10- and 100-L samples. In addition, detection levels for pathogens in seeded 100-L reclaimed water samples were 1000 PFU HAV, 10,000 GI norovirus particles, <500 Salmonella and <200 Cryptosporidium oocysts. These data demonstrate that UF can be an effective technique for recovering diverse microbes in reclaimed water to monitor and improve effluent water quality in wastewater treatment plants. JF - Journal of Microbiological Methods AU - Liu, Pengbo AU - Hill, Vincent R AU - Hahn, Donghyun AU - Johnson, Trisha B AU - Pan, Yi AU - Jothikumar, Narayanan AU - Moe, Christine L AD - Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA, vhill@cdc.gov Y1 - 2012/01// PY - 2012 DA - Jan 2012 SP - 155 EP - 161 PB - Elsevier B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 88 IS - 1 SN - 0167-7012, 0167-7012 KW - Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Phages KW - Ultrafiltration KW - Parasites KW - Data processing KW - Oocysts KW - Water reclamation KW - Reclaimed water KW - Clostridium perfringens KW - Norovirus KW - Water quality KW - Effluents KW - Wastewater treatment KW - Cryptosporidium parvum KW - Dialyzers KW - Waste water KW - Spores KW - Salmonella KW - V 22300:Methods KW - A 01300:Methods KW - J 02300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/918066535?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Microbiological+Methods&rft.atitle=Hollow-fiber+ultrafiltration+for+simultaneous+recovery+of+viruses%2C+bacteria+and+parasites+from+reclaimed+water&rft.au=Liu%2C+Pengbo%3BHill%2C+Vincent+R%3BHahn%2C+Donghyun%3BJohnson%2C+Trisha+B%3BPan%2C+Yi%3BJothikumar%2C+Narayanan%3BMoe%2C+Christine+L&rft.aulast=Liu&rft.aufirst=Pengbo&rft.date=2012-01-01&rft.volume=88&rft.issue=1&rft.spage=155&rft.isbn=&rft.btitle=&rft.title=Journal+of+Microbiological+Methods&rft.issn=01677012&rft_id=info:doi/10.1016%2Fj.mimet.2011.11.007 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-01-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Ultrafiltration; Phages; Parasites; Data processing; Water reclamation; Oocysts; Reclaimed water; Effluents; Water quality; Wastewater treatment; Dialyzers; Spores; Waste water; Clostridium perfringens; Norovirus; Salmonella; Cryptosporidium parvum DO - http://dx.doi.org/10.1016/j.mimet.2011.11.007 ER - TY - JOUR T1 - Development of a method to estimate mouth-level benzo[a]pyrene intake by filter analysis. AN - 915040239; 22028404 AB - Benzo[a]pyrene (BaP) is one of the most potent carcinogens generated in cigarette smoke. During smoking, cigarette filters trap a significant portion of mainstream smoke benzo[a]pyrene. This trapped portion is proportional to what exits the end of the filter and is drawn into the mouth of smokers. We developed a new method to estimate mouth-level BaP intake using filter analysis. In this analysis, cigarettes are smoked by a smoking machine using a variety of conditions to yield a range of mainstream smoke deliveries, which approximate a range of human puffing characteristics. Mainstream smoke BaP collected on Cambridge filter pads and the corresponding 1-cm mouth-end cigarette filter butts is extracted, purified by solid-phase extraction, and quantified by high-performance liquid chromatography coupled with a fluorescence detector. On the basis of the amount of BaP retained in cigarette butts and the amount collected on pads, we can relate them using a linear regression model. Using this model and subsequently analyzing cigarette filters collected from smokers, we are able to estimate their mouth-level intakes, which smokers received when they consumed cigarettes. We made a series of measurements using research cigarettes and select commercial cigarettes having a wide range of machine smoke "tar" and nicotine deliveries. In all cases, results indicate a linear relation of BaP between cigarette filter butts and Cambridge filter pads, with R(2) ranging from 0.93 to 0.98. This technique provides a noninvasive means to examine intake on a per cigarette basis to examine both exposure and behavioral aspects of smoking. JF - Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology AU - Ding, Yan S AU - Chou, Theodore AU - Abdul-Salaam, Shadeed AU - Hearn, Bryan AU - Watson, Clifford H AD - Division of Laboratory Science, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, Mailstop F-47, Atlanta, GA 30341, USA. yding@cdc.gov Y1 - 2012/01// PY - 2012 DA - January 2012 SP - 39 EP - 44 VL - 21 IS - 1 KW - Carcinogens KW - 0 KW - Smoke KW - Benzo(a)pyrene KW - 3417WMA06D KW - Index Medicus KW - Carcinogens -- administration & dosage KW - Spectrometry, Fluorescence -- methods KW - Reproducibility of Results KW - Humans KW - Carcinogens -- chemistry KW - Linear Models KW - Chromatography, High Pressure Liquid -- methods KW - Carcinogens -- analysis KW - Filtration -- methods KW - Benzo(a)pyrene -- administration & dosage KW - Benzo(a)pyrene -- analysis KW - Tobacco -- chemistry KW - Smoke -- analysis KW - Benzo(a)pyrene -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/915040239?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cancer+epidemiology%2C+biomarkers+%26+prevention+%3A+a+publication+of+the+American+Association+for+Cancer+Research%2C+cosponsored+by+the+American+Society+of+Preventive+Oncology&rft.atitle=Development+of+a+method+to+estimate+mouth-level+benzo%5Ba%5Dpyrene+intake+by+filter+analysis.&rft.au=Ding%2C+Yan+S%3BChou%2C+Theodore%3BAbdul-Salaam%2C+Shadeed%3BHearn%2C+Bryan%3BWatson%2C+Clifford+H&rft.aulast=Ding&rft.aufirst=Yan&rft.date=2012-01-01&rft.volume=21&rft.issue=1&rft.spage=39&rft.isbn=&rft.btitle=&rft.title=Cancer+epidemiology%2C+biomarkers+%26+prevention+%3A+a+publication+of+the+American+Association+for+Cancer+Research%2C+cosponsored+by+the+American+Society+of+Preventive+Oncology&rft.issn=1538-7755&rft_id=info:doi/10.1158%2F1055-9965.EPI-11-0800 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-04-25 N1 - Date created - 2012-01-09 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1158/1055-9965.EPI-11-0800 ER - TY - JOUR T1 - Translational research to develop a human PBPK models tool kit-volatile organic compounds (VOCs). AN - 902344303; 22047160 AB - Toxicity and exposure evaluations remain the two of the key components of human health assessment. While improvement in exposure assessment relies on a better understanding of human behavior patterns, toxicity assessment still relies to a great extent on animal toxicity testing and human epidemiological studies. Recent advances in computer modeling of the dose-response relationship and distribution of xenobiotics in humans to important target tissues have advanced our abilities to assess toxicity. In particular, physiologically based pharmacokinetic (PBPK) models are among the tools than can enhance toxicity assessment accuracy. Many PBPK models are available to the health assessor, but most are so difficult to use that health assessors rarely use them. To encourage their use these models need to have transparent and user-friendly formats. To this end the Agency for Toxic Substances and Disease Registry (ATSDR) is using translational research to increase PBPK model accessibility, understandability, and use in the site-specific health assessment arena. The agency has initiated development of a human PBPK tool-kit for certain high priority pollutants. The tool kit comprises a series of suitable models. The models are recoded in a single computer simulation language and evaluated for use by health assessors. While not necessarily being state-of-the-art code for each chemical, the models will be sufficiently accurate to use for screening purposes. This article presents a generic, seven-compartment PBPK model for six priority volatile organic compounds (VOCs): benzene (BEN), carbon tetrachloride (CCl(4)), dichloromethane (DCM), perchloroethylene (PCE), trichloroethylene (TCE), and vinyl chloride (VC). Limited comparisons of the generic and original model predictions to published kinetic data were conducted. A goodness of fit was determined by calculating the means of the sum of the squared differences (MSSDs) for simulation vs. experimental kinetic data using the generic and original models. Using simplified solvent exposure assumptions for oral ingestion and inhalation, steady-state blood concentrations of each solvent were simulated for exposures equivalent to the ATSDR Minimal Risk Levels (MRLs). The predicted blood levels were then compared to those reported in the National Health and Nutrition Examination Survey (NHANES). With the notable exception of BEN, simulations of combined oral and inhalation MRLs using our generic VOC model yielded blood concentrations well above those reported for the 95th percentile blood concentrations for the U.S. populations, suggesting no health concerns. When the PBPK tool kit is fully developed, risk assessors will have a readily accessible tool for evaluating human exposure to a variety of environmental pollutants. JF - Journal of toxicology and environmental health. Part A AU - Mumtaz, M Moiz AU - Ray, Meredith AU - Crowell, Susan R AU - Keys, Deborah AU - Fisher, Jeffrey AU - Ruiz, Patricia AD - Division of Toxicology and Environmental Medicine, Agency for Toxic Substances and Disease Registry, Atlanta, Georgia 30333, USA. mgm4@cdc.gov Y1 - 2012 PY - 2012 DA - 2012 SP - 6 EP - 24 VL - 75 IS - 1 SN - 1528-7394, 1528-7394 KW - Environmental Pollutants KW - 0 KW - Volatile Organic Compounds KW - Index Medicus KW - United States KW - Computer Simulation KW - Epidemiologic Studies KW - Public Health -- methods KW - Humans KW - Risk Assessment -- methods KW - Environmental Pollutants -- toxicity KW - Volatile Organic Compounds -- classification KW - Environmental Pollutants -- chemistry KW - Volatile Organic Compounds -- toxicity KW - Research Design KW - Models, Biological KW - Volatile Organic Compounds -- pharmacokinetics KW - Environmental Pollutants -- pharmacokinetics KW - Environmental Monitoring -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/902344303?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+toxicology+and+environmental+health.+Part+A&rft.atitle=Translational+research+to+develop+a+human+PBPK+models+tool+kit-volatile+organic+compounds+%28VOCs%29.&rft.au=Mumtaz%2C+M+Moiz%3BRay%2C+Meredith%3BCrowell%2C+Susan+R%3BKeys%2C+Deborah%3BFisher%2C+Jeffrey%3BRuiz%2C+Patricia&rft.aulast=Mumtaz&rft.aufirst=M&rft.date=2012-01-01&rft.volume=75&rft.issue=1&rft.spage=6&rft.isbn=&rft.btitle=&rft.title=Journal+of+toxicology+and+environmental+health.+Part+A&rft.issn=15287394&rft_id=info:doi/10.1080%2F15287394.2012.625546 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-12-21 N1 - Date created - 2011-11-03 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1080/15287394.2012.625546 ER - TY - JOUR T1 - Population-Level Intervention Strategies and Examples for Obesity Prevention in Children AN - 1837308637; 17254247 AB - With obesity affecting approximately 12.5 million American youth, population-level interventions are indicated to help support healthy behaviors. The purpose of this review is to provide a summary of population-level intervention strategies and specific intervention examples that illustrate ways to help prevent and control obesity in children through improving nutrition and physical activity behaviors. Information is summarized within the settings where children live, learn, and play (early care and education, school, community, health care, home). Intervention strategies are activities or changes intended to promote healthful behaviors in children. They were identified from (a) systematic reviews; (b) evidence- and expert consensus-based recommendations, guidelines, or standards from nongovernmental or federal agencies; and finally (c) peer-reviewed synthesis reviews. Intervention examples illustrate how at least one of the strategies was used in a particular setting. To identify interventions examples, we considered (a) peer-reviewed literature as well as (b) additional sources with research-tested and practice-based initiatives. Researchers and practitioners may use this review as they set priorities and promote integration across settings and to find research- and practice-tested intervention examples that can be replicated in their communities for childhood obesity prevention. JF - Annual Review of Nutrition AU - Foltz, J L AU - May, AL AU - Belay, B AU - Nihiser, A J AU - Dooyema, CA AU - Blanck, H M AD - Division of Nutrition, Physical Activity, and Obesity, Atlanta, Georgia 30341, USA, JFoltz@cdc.gov Y1 - 2012///0, PY - 2012 DA - 0, 2012 SP - 391 EP - 415 VL - 32 SN - 0199-9885, 0199-9885 KW - Physical Education Index KW - Obesity KW - Home KW - Preventive health KW - Promotion KW - Strategy KW - School health KW - Children KW - Activities KW - Nutrition KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1837308637?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annual+Review+of+Nutrition&rft.atitle=Population-Level+Intervention+Strategies+and+Examples+for+Obesity+Prevention+in+Children&rft.au=Foltz%2C+J+L%3BMay%2C+AL%3BBelay%2C+B%3BNihiser%2C+A+J%3BDooyema%2C+CA%3BBlanck%2C+H+M&rft.aulast=Foltz&rft.aufirst=J&rft.date=2012-01-01&rft.volume=32&rft.issue=&rft.spage=391&rft.isbn=&rft.btitle=&rft.title=Annual+Review+of+Nutrition&rft.issn=01999885&rft_id=info:doi/10.1146%2Fannurev-nutr-071811-150646 LA - English DB - Physical Education Index N1 - Date revised - 2016-11-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Obesity; Home; Preventive health; Promotion; Strategy; School health; Activities; Children; Nutrition DO - http://dx.doi.org/10.1146/annurev-nutr-071811-150646 ER - TY - JOUR T1 - Evaluating Changes in the Prevalence of the Autism Spectrum Disorders (ASDs) AN - 1627733184 AB - Autism spectrum disorders (ASDs) are estimated to occurʼ among about one percent of children in the United States. This estimate is in line with estimates from other industrialized counties. However, the identified prevalence of ASDs has increased significantly in a short time period based on data from multiple studies including the U.S. Centers for Disease Control and Preventionʼs (CDC) Autism and Developmental Disabilities Monitoring (ADDM) Network. Whether increases in ASD prevalence are partly attributable to a true increase in the risk of developing ASD or solely to changes in community awareness and identification patterns is not known. It is clear that more children are identified with an ASD now than in the past and the impact on individuals, families, and communities is significant. However, disentangling the many potential reasons for ASD prevalence increases has been challenging. Understanding the relative contribution of multiple factors such as variation in study methods, changes in diagnostic and community identification, and potential changes in risk factors is an important priority for the ADDM Network and for CDC. This article summarizes the discussion from a workshop that was co-sponsored by CDC and Autism Speaks as a forum for sharing knowledge and opinions of a diverse range of stakeholders about changes in ASD prevalence. Panelists discussed recommendations for building on existing infrastructure and developing new initiatives to better understand ASD trends. The information, research, and opinions shared during this workshop add to the knowledge base about ASD prevalence in an effort to stimulate further work to understand the multiple reasons behind increasing ASD prevalence. JF - Public Health Reviews AU - Rice, Catherine E AU - Rosanoff, Michael AU - Dawson, Geraldine AU - Durkin, Maureen S AU - Croen, Lisa A AU - Singer, Alison AU - Yeargin-Allsopp, Marshalyn AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 1600 Clifton Road, MS E-86, Atlanta, Georgia, 30333, USA ; Autism Speaks, USA ; Autism Speaks, USA; University of North Carolina at Chapel Hill, USA ; University of Wisconsin-Madison, USA ; Kaiser Permanente(R) Autism Research Program, USA ; Autism Science Foundation, USA ; National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, USA ; National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 1600 Clifton Road, MS E-86, Atlanta, Georgia, 30333, USA Y1 - 2012 PY - 2012 DA - 2012 SP - 1 EP - 22 CY - Dordrecht PB - Springer Science & Business Media VL - 34 IS - 2 SN - 0301-0422 KW - Medical Sciences--Oncology KW - Autism KW - autism spectrum disorders KW - ASD KW - prevalence KW - occurrence KW - Autistic children KW - Change agents KW - Communities KW - Infrastructure KW - Knowledge base KW - Stakeholders KW - Autistic spectrum disorders KW - Identification KW - Prevalence KW - Risk factors KW - United States--US UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1627733184?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Public+Health+Reviews&rft.atitle=Evaluating+Changes+in+the+Prevalence+of+the+Autism+Spectrum+Disorders+%28ASDs%29&rft.au=Rice%2C+Catherine+E%3BRosanoff%2C+Michael%3BDawson%2C+Geraldine%3BDurkin%2C+Maureen+S%3BCroen%2C+Lisa+A%3BSinger%2C+Alison%3BYeargin-Allsopp%2C+Marshalyn&rft.aulast=Rice&rft.aufirst=Catherine&rft.date=2012-01-01&rft.volume=34&rft.issue=2&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Public+Health+Reviews&rft.issn=03010422&rft_id=info:doi/ LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Name - Centers for Disease Control & Prevention--CDC N1 - Date revised - 2014-10-14 N1 - Last updated - 2016-05-13 N1 - SubjectsTermNotLitGenreText - United States--US ER - TY - JOUR T1 - Compliance With Bloodborne Pathogen Standards at Eight Correctional Facilities AN - 1434034750; 18507524 AB - This study had three objectives: (a) to examine compliance with the Occupational Safety and Health Administration (OSHA) Bloodborne Pathogens (BBPs) Standard at eight correctional facilities, (b) to identify potential barriers to compliance, and (c) to discuss steps to address these barriers. Eight facilities of different sizes and locations were visited to examine employer adherence to 15 selected BBP risk reduction activities. Facility compliance was less than 50% for four activities: updating exposure control plans, implementing use of appropriate safer medical devices, soliciting employee input on selection of safer devices, and training medical staff when such devices are implemented. Inconsistent compliance may be due to difficulties in applying the standards in the correctional health care work setting. Any BBP training and health communication activities targeted to correctional health care workers should be tailored to the correctional facility setting. JF - Journal of Correctional Health Care AU - Lehman, Everett J AU - Huy, Janice M AU - Viet, Susan M AU - Gomaa, Ahmed AD - Industrywide Studies Branch, Division of Surveillance, Hazard Evaluations and Field Studies, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, OH, USA  , ELehman@cdc.gov Y1 - 2012/01// PY - 2012 DA - Jan 2012 SP - 29 EP - 44 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU United Kingdom VL - 18 IS - 1 SN - 1078-3458, 1078-3458 KW - Health & Safety Science Abstracts; Risk Abstracts KW - Prisons KW - Communications KW - Safety regulations KW - Health care KW - Training KW - Compliance KW - Pathogens KW - Risk reduction KW - Medical personnel KW - H 1000:Occupational Safety and Health KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1434034750?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Correctional+Health+Care&rft.atitle=Compliance+With+Bloodborne+Pathogen+Standards+at+Eight+Correctional+Facilities&rft.au=Lehman%2C+Everett+J%3BHuy%2C+Janice+M%3BViet%2C+Susan+M%3BGomaa%2C+Ahmed&rft.aulast=Lehman&rft.aufirst=Everett&rft.date=2012-01-01&rft.volume=18&rft.issue=1&rft.spage=29&rft.isbn=&rft.btitle=&rft.title=Journal+of+Correctional+Health+Care&rft.issn=10783458&rft_id=info:doi/10.1177%2F1078345811421466 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-09-01 N1 - Number of references - 28 N1 - Last updated - 2013-10-21 N1 - SubjectsTermNotLitGenreText - Prisons; Safety regulations; Communications; Health care; Training; Compliance; Risk reduction; Pathogens; Medical personnel DO - http://dx.doi.org/10.1177/1078345811421466 ER - TY - JOUR T1 - Are Adolescent Cigarette Smokers Who Use Smokeless Tobacco More Likely to Continue Smoking in the Future than Cigarette-Only Smokers: Results from Waves I and II of the Adolescent Health Survey AN - 1328510482; 17382933 AB - We explored whether dual use of smokeless and cigarettes among adolescents predicts continued smoking. Data came from Waves I (1994-95) and II (1996) of the National Longitudinal Study of Adolescent Health, using information from 3,284 Wave I current smokers. Multivariate models were used to assess whether use of smokeless tobacco at Wave I was associated with continuation of cigarette smoking at Wave II, controlling for possible confounders. The prevalence of current cigarette smoking at Wave 1 was 27.9%; among this group of adolescents and young adults, 14.5% also used smokeless tobacco. At Wave II, 73.6% of dual product users and 78.4% of cigarette-only users in Wave I reported continued smoking ( OR=0.71 [95% CI 0.52-0.98]). Combined use of cigarette and smokeless tobacco does not appear to be related to continued smoking one year later. Longer-term followups are needed to determine the stability of this relationship for > or =1 year. JF - ISRN Public Health AU - O'Hegarty, Michelle M AU - Pederson, Linda L AU - Asman, Katherine J AU - Malarcher, Ann M AU - Mirza, Sara A AD - Centers for Disease Control and Prevention, Office on Smoking and Health, 4770 Buford Highway N.E., Mailstop K-50, Atlanta, GA 30341-3717, USA, mohegarty@cdc.gov Y1 - 2012/01// PY - 2012 DA - Jan 2012 PB - Hindawi Publishing Corporation, P.O. Box 3079 Cuyahoga Falls OH 44223 United States VL - 2012 KW - Health & Safety Science Abstracts KW - Adolescents KW - Cigarette smoking KW - Longitudinal studies KW - Tobacco KW - Young adults KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1328510482?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=ISRN+Public+Health&rft.atitle=Are+Adolescent+Cigarette+Smokers+Who+Use+Smokeless+Tobacco+More+Likely+to+Continue+Smoking+in+the+Future+than+Cigarette-Only+Smokers%3A+Results+from+Waves+I+and+II+of+the+Adolescent+Health+Survey&rft.au=O%27Hegarty%2C+Michelle+M%3BPederson%2C+Linda+L%3BAsman%2C+Katherine+J%3BMalarcher%2C+Ann+M%3BMirza%2C+Sara+A&rft.aulast=O%27Hegarty&rft.aufirst=Michelle&rft.date=2012-01-01&rft.volume=2012&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=ISRN+Public+Health&rft.issn=2090-8008&rft_id=info:doi/10.5402%2F2012%2F304508 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-04-01 N1 - Number of references - 18 N1 - Last updated - 2013-05-06 N1 - SubjectsTermNotLitGenreText - Longitudinal studies; Cigarette smoking; Tobacco; Young adults; Adolescents DO - http://dx.doi.org/10.5402/2012/304508 ER - TY - JOUR T1 - How the Most Trusted Venues for Health-Related Information Influence Physician Referrals to Smoking Cessation Services AN - 1328509979; 17382934 AB - Public health programs seek to educate physicians by using a variety of venues. Therefore, it is important to understand which health information sources physicians are using and how these sources affect referrals. We explored how venues for health-related information affect physicians' referral practices to smoking cessation services. The 2008 DocStyles survey asked physicians to rank a list of their most trusted sources of health-related information. The analysis was restricted to 1,617 physicians who responded to all variables of interest. In this sample, the most trusted sources of health-related information cited by physicians were medical journals (95.9%), government health agencies (82.2%), other physicians (76.4%), professional medical societies (75.2%), and medical Web sites or podcasts (65.9%). Medical providers were more likely to refer tobacco users to cessation services if they used professional medical societies as a source to obtain patient health-related information, compared with medical providers not using this source (multivariate odds ratio = 1.31; 95% confidence interval = 1.03-1.66). Physicians use many health information sources. Therefore, to reach physicians effectively, a broad dissemination of guidelines and best practices in tobacco control is needed and should include information for medical societies. JF - ISRN Public Health AU - Kruger, Judy AU - Trosclair, Angela AU - Bruce, Crystal AU - Beistle, Diane AD - Office on Smoking and Health, Centers for Disease Control and Prevention, 4770 Buford Highway NE, K-50, Atlanta, GA 30341-3717, USA, ezk0@cdc.gov Y1 - 2012/01// PY - 2012 DA - Jan 2012 PB - Hindawi Publishing Corporation, P.O. Box 3079 Cuyahoga Falls OH 44223 United States VL - 2012 KW - Health & Safety Science Abstracts KW - Best practices KW - Guidelines KW - Public health KW - Smoking KW - Tobacco KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1328509979?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=ISRN+Public+Health&rft.atitle=How+the+Most+Trusted+Venues+for+Health-Related+Information+Influence+Physician+Referrals+to+Smoking+Cessation+Services&rft.au=Kruger%2C+Judy%3BTrosclair%2C+Angela%3BBruce%2C+Crystal%3BBeistle%2C+Diane&rft.aulast=Kruger&rft.aufirst=Judy&rft.date=2012-01-01&rft.volume=2012&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=ISRN+Public+Health&rft.issn=2090-8008&rft_id=info:doi/10.5402%2F2012%2F256301 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-04-01 N1 - Last updated - 2013-05-06 N1 - SubjectsTermNotLitGenreText - Smoking; Best practices; Guidelines; Tobacco; Public health DO - http://dx.doi.org/10.5402/2012/256301 ER - TY - JOUR T1 - Support for a Dimensional View of Autism Spectrum Disorders in Toddlers AN - 1323338250; 201305328 AB - We examined whether clinically distinct subgroups can be derived from a sample of toddlers (n = 186) who failed the Modified Checklist for Autism in Toddlers, received a comprehensive clinical evaluation, and were diagnosed with an autism spectrum disorder (ASD). Three subgroups emerged from cluster analysis distinguished by (a) social, communication, and intellectual skills and (b) the rate and intensity of repetitive behaviors and abnormal sensory response. Preoccupations, compulsions, and rituals did not distinguish resultant subgroups. These results support a dimensional diagnostic view of ASDs in toddlers since subgroup differences were based on symptom severity rather than different symptom profiles. Results also identify specific types and levels of behavioral deficit relevant to toddler populations. Implications for early diagnosis are discussed. Adapted from the source document. JF - Journal of Autism and Developmental Disorders AU - Wiggins, Lisa D AU - Robins, Diana L AU - Adamson, Lauren B AU - Bakeman, Roger AU - Henrich, Christopher C AD - Georgia State University, Atlanta, GA, USA lwiggins@cdc.gov Y1 - 2012///0, PY - 2012 DA - 0, 2012 SP - 191 EP - 200 PB - Springer, Dordrecht The Netherlands VL - 42 IS - 2 SN - 0162-3257, 0162-3257 KW - Symptoms KW - Preoccupation KW - Attitudes KW - Young children KW - Repetitive behaviour KW - Autistic spectrum disorders KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1323338250?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Autism+and+Developmental+Disorders&rft.atitle=Support+for+a+Dimensional+View+of+Autism+Spectrum+Disorders+in+Toddlers&rft.au=Wiggins%2C+Lisa+D%3BRobins%2C+Diana+L%3BAdamson%2C+Lauren+B%3BBakeman%2C+Roger%3BHenrich%2C+Christopher+C&rft.aulast=Wiggins&rft.aufirst=Lisa&rft.date=2012-01-01&rft.volume=42&rft.issue=2&rft.spage=191&rft.isbn=&rft.btitle=&rft.title=Journal+of+Autism+and+Developmental+Disorders&rft.issn=01623257&rft_id=info:doi/10.1007%2Fs10803-011-1230-0 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2013-04-01 N1 - Last updated - 2016-09-27 N1 - CODEN - JADDDQ N1 - SubjectsTermNotLitGenreText - Young children; Autistic spectrum disorders; Symptoms; Attitudes; Preoccupation; Repetitive behaviour DO - http://dx.doi.org/10.1007/s10803-011-1230-0 ER - TY - JOUR T1 - Associated factors for recommending HBV vaccination to children among Georgian health care workers AN - 1291618440; 17592676 AB - Background: Most cases of hepatitis B virus (HBV) infection and subsequent liver diseases can be prevented with universal newborn HBV vaccination. The attitudes of health care workers about HBV vaccination and their willingness to recommend vaccine have been shown to impact HBV vaccination coverage and the prevention of vertical transmission of HBV. The purpose of this study was to ascertain the factors associated with health care worker recommendations regarding newborn HBV vaccination. Methods: A cross-sectional study of prevalence and awareness of hepatitis B and hepatitis B vaccine was conducted among randomly selected physicians and nurses employed in seven hospitals in Georgia in 2006 and 2007. Self-administered questionnaires included a module on recommendations for HBV, HCV and HIV. Results: Of the 1328 participants included in this analysis, 36% reported recommending against hepatitis B vaccination for children, including 33% of paediatricians. Among the 70.6% who provided a reason for not recommending HBV vaccine, the most common concern was an adverse vaccine event. Unvaccinated physicians and nurses were more likely to recommend against HBV vaccine (40.4% vs 11.4%, PR 3.54; 95% CI: 2.38, 5.29). Additionally, health care worker age was inversely correlated with recommendations for HBV vaccine with older workers less likely to recommend it. Conclusion: Vaccinating health care workers against HBV may provide a dual benefit by boosting occupational safety as well as strengthening universal coverage programs for newborns. JF - BMC Infectious Diseases AU - Butsashvili, Maia AU - Kamkamidze, George AU - Topuridze, Marina AU - Morse, Dale AU - Triner, Wayne AU - DeHovitz, Jack AU - Nelson, Kenrad AU - McNutt, Louise-Anne AD - National Center for Disease Control and Public Health (NCDC), 9 Asatiani st., Tbilisi, 0177, Georgia Y1 - 2012 PY - 2012 DA - 2012 SP - 362 PB - BioMed Central Ltd., Middlesex House London W1T 4LB United Kingdom VL - 12 IS - 1 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Age KW - Hepatitis B virus KW - USA, Georgia KW - Vaccines KW - Medical personnel KW - V:22360 KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1291618440?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=BMC+Infectious+Diseases&rft.atitle=Associated+factors+for+recommending+HBV+vaccination+to+children+among+Georgian+health+care+workers&rft.au=Butsashvili%2C+Maia%3BKamkamidze%2C+George%3BTopuridze%2C+Marina%3BMorse%2C+Dale%3BTriner%2C+Wayne%3BDeHovitz%2C+Jack%3BNelson%2C+Kenrad%3BMcNutt%2C+Louise-Anne&rft.aulast=Butsashvili&rft.aufirst=Maia&rft.date=2012-01-01&rft.volume=12&rft.issue=1&rft.spage=362&rft.isbn=&rft.btitle=&rft.title=BMC+Infectious+Diseases&rft.issn=1471-2334&rft_id=info:doi/10.1186%2F1471-2334-12-362 L2 - http://www.biomedcentral.com/1471-2334/12/362 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-01 N1 - Number of references - 1 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Vaccines; Medical personnel; Hepatitis B virus; USA, Georgia DO - http://dx.doi.org/10.1186/1471-2334-12-362 ER - TY - JOUR T1 - A Nationwide Community-Based Lifestyle Program Could Delay Or Prevent Type 2 Diabetes Cases And Save $5.7 Billion In 25 Years AN - 1257859152; 16199529 AB - The increasing health and economic burden of diabetes has made preventing the disease a public health priority. But investing in such chronic disease prevention programs requires a long-term horizon because many years may be required for the downstream savings to fully offset the up-front intervention cost. Using a simulation model, we projected the costs and benefits of a nationwide community-based lifestyle intervention program for preventing type 2 diabetes. Accounting for all costs to the US health care system, our results indicate that the program would break even in fourteen years. Within twenty-five years, the program would prevent or delay about 885,000 cases of type 2 diabetes in the United States and produce savings of $5.7 billion nationwide. If restricted to people ages 65-84, the program would save $2.4 billion. Thus, implementing such a program nationwide would be an efficient use of health care resources, although it might be necessary for all health insurers to participate to share prevention costs. Our results also indicate that although a prevention program would lead to cost savings in both younger and older people, it would achieve greater health and economic gains if it were directed at people under age sixty-five. JF - Health Affairs AU - Zhuo, Xiaohui AU - Zhang, Ping AU - Gregg, Edward W AU - Barker, Lawrence AU - Hoerger, Thomas J AU - Albright, Ann AD - Xiaohui Zhuo is a health economist at the Centers for Disease Control and Prevention (CDC), in Atlanta, Georgia. Ping Zhang is a senior health economist at the CDC. Edward W. Gregg is the acting director of the Division of Heart Disease and Stroke Prevention, CDC. Lawrence Barker is a senior scientist at the CDC. Thomas J. Hoerger is a senior fellow and director of the RTI-UNC Center of Excellence in Health Promotion Economics, in Research Triangle Park, North Carolina. Tony Pearson-Clarke is a health writer and editor at the CDC. Ann Albright is director of the Division of Diabetes Translation, CDC., iip6@cdc.gov Y1 - 2012 PY - 2012 DA - 2012 SP - 50 EP - 60 PB - Project Hope, 7500 Old Georgetown Rd. Suite 600 Bethesda MD 20814-6133 United States VL - 31 IS - 1 SN - 0278-2715, 0278-2715 KW - Health & Safety Science Abstracts KW - Age KW - Community involvement KW - Diabetes mellitus KW - Downstream KW - Economics KW - Health care KW - Intervention KW - Prevention KW - Public health KW - USA KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1257859152?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+Affairs&rft.atitle=A+Nationwide+Community-Based+Lifestyle+Program+Could+Delay+Or+Prevent+Type+2+Diabetes+Cases+And+Save+%245.7+Billion+In+25+Years&rft.au=Zhuo%2C+Xiaohui%3BZhang%2C+Ping%3BGregg%2C+Edward+W%3BBarker%2C+Lawrence%3BHoerger%2C+Thomas+J%3BAlbright%2C+Ann&rft.aulast=Zhuo&rft.aufirst=Xiaohui&rft.date=2012-01-01&rft.volume=31&rft.issue=1&rft.spage=50&rft.isbn=&rft.btitle=&rft.title=Health+Affairs&rft.issn=02782715&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-12-01 N1 - Last updated - 2013-01-25 N1 - SubjectsTermNotLitGenreText - Diabetes mellitus; Age; Prevention; Health care; Community involvement; Economics; Intervention; Downstream; Public health; USA ER - TY - JOUR T1 - Addressing Inequities in Access to Health Products through the Use of Social Marketing, Community Mobilization, and Local Entrepreneurs in Rural Western Kenya AN - 1238118047; 17315919 AB - While social marketing can increase uptake of health products in developing countries, providing equitable access is challenging. We conducted a 2-year evaluation of uptake of WaterGuard, insecticide-treated bednets (ITNs), and micronutrient Sprinkles in Western Kenya. Sixty villages were randomly assigned to intervention and comparison groups. Following a baseline survey (BL), a multifaceted intervention comprising social marketing of these products, home visits by product vendors from a local women's group (Safe Water and AIDS Project, or SWAP), product promotions, and modeling of water treatment and safe storage in was implemented in intervention villages. Comparison villages received only social marketing of WaterGuard and ITNs. We surveyed again at one year (FU1), implemented the intervention in comparison villages, and surveyed again at two years (FU2). At BL, 90% those reported ever purchasing a product from the vendor. WaterGuard ( P=0.02 ) and ITNs ( P=0.005 ) were purchased less frequently by lower-SES than higher-SES households; Sprinkles, the least expensive product, was purchased equally across all quintiles. JF - International Journal of Population Research AU - Harris, Julie R AU - Patel, Minal K AU - Juliao, Patricia AU - Suchdev, Parminder S AU - Ruth, Laird J AU - Were, Vincent AU - Ochieng, Cliff AU - Faith, Sitnah Hamidah AU - Kola, Steven AU - Otieno, Ronald AU - Sadumah, Ibrahim AU - Obure, Alfredo AU - Quick, Robert AD - Epidemic Intelligence Service, Office of Workforce and Career Development, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA, ggt5@cdc.gov Y1 - 2012/01// PY - 2012 DA - Jan 2012 PB - Hindawi Publishing Corporation, P.O. Box 3079 Cuyahoga Falls OH 44223 United States VL - 2012 SN - 2090-4029, 2090-4029 KW - Pollution Abstracts KW - Acquired immune deficiency syndrome KW - Developing countries KW - Households KW - Intervention KW - Marketing KW - Micronutrients KW - Rural areas KW - Villages KW - Water treatment KW - Kenya KW - P 2000:FRESHWATER POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1238118047?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Population+Research&rft.atitle=Addressing+Inequities+in+Access+to+Health+Products+through+the+Use+of+Social+Marketing%2C+Community+Mobilization%2C+and+Local+Entrepreneurs+in+Rural+Western+Kenya&rft.au=Harris%2C+Julie+R%3BPatel%2C+Minal+K%3BJuliao%2C+Patricia%3BSuchdev%2C+Parminder+S%3BRuth%2C+Laird+J%3BWere%2C+Vincent%3BOchieng%2C+Cliff%3BFaith%2C+Sitnah+Hamidah%3BKola%2C+Steven%3BOtieno%2C+Ronald%3BSadumah%2C+Ibrahim%3BObure%2C+Alfredo%3BQuick%2C+Robert&rft.aulast=Harris&rft.aufirst=Julie&rft.date=2012-01-01&rft.volume=2012&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Population+Research&rft.issn=20904029&rft_id=info:doi/10.1155%2F2012%2F470598 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-12-01 N1 - Number of references - 30 N1 - Last updated - 2013-01-11 N1 - SubjectsTermNotLitGenreText - Acquired immune deficiency syndrome; Water treatment; Villages; Households; Marketing; Intervention; Micronutrients; Developing countries; Rural areas; Kenya DO - http://dx.doi.org/10.1155/2012/470598 ER - TY - JOUR T1 - Effect of calibration and environmental condition on the performance of direct-reading organic vapor monitors. AN - 1081437097; 23016630 AB - The performance of three MIRAN SapphIRe Portable Infrared Ambient Air Analyzers and three Century Portable Toxic Vapor Analyzers equipped with photoionization (PID) and flame ionization (FID) detectors was compared with charcoal tube sampling. Relationships were investigated using two different calibration methods at four cyclohexane concentrations, three temperatures, and four relative humidities. For the first method, the TVA monitors were calibrated with a single concentration of methane for the FID, and isobutylene for the PID. The SapphIRe monitors were zeroed and the monitor's manufacturer-supplied library was used. For the second method, a five-point cyclohexane calibration curve was created for each monitor. Comparison of the monitor results of each calibration method (pooled data) indicated a significant difference between methods (t-test, p < 0.001), The SapphIRe group had results closer to the charcoal tubes with the second calibration method, while the PID and FID monitor groups performed better using the first calibration method. The PID monitor group's performance was affected only at the 90% relative humidity (RH) condition. Using the first method, the monitor readings were compared with the charcoal tube average using mixed linear model analyses of variance (ANOVAs) and regression. The ANOVA results showed there was a statistically significant difference among readings from all monitor types (p <0.0001). The regression results demonstrated that the SapphIRe (r² = 0.97) and FID (r² = 0.92) monitor groups correlated well with the charcoal tubes. The PID monitor group had a similar correlation when 90% RH was excluded (r² = 0.94) but had a weaker correlation when it was included (r² = 0.58). The operator should take care when using these monitors at high concentrations and the PID monitors at high humidities, consider the variability between units of the same monitor, and conduct performance verification of the monitor being used. JF - Journal of occupational and environmental hygiene AU - Coffey, Christopher AU - LeBouf, Ryan AU - Lee, Larry AU - Slaven, James AU - Martin, Stephen AD - National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505, USA. ccc3@cdc.gov Y1 - 2012 PY - 2012 DA - 2012 SP - 670 EP - 680 VL - 9 IS - 11 KW - Air Pollutants, Occupational KW - 0 KW - Cyclohexanes KW - Cyclohexane KW - 48K5MKG32S KW - Index Medicus KW - False Negative Reactions KW - Analysis of Variance KW - Flame Ionization KW - Linear Models KW - Temperature KW - Photochemical Processes KW - Humidity KW - Calibration KW - False Positive Reactions KW - Air Pollutants, Occupational -- analysis KW - Cyclohexanes -- analysis KW - Occupational Exposure -- analysis KW - Environmental Monitoring -- instrumentation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1081437097?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+occupational+and+environmental+hygiene&rft.atitle=Effect+of+calibration+and+environmental+condition+on+the+performance+of+direct-reading+organic+vapor+monitors.&rft.au=Coffey%2C+Christopher%3BLeBouf%2C+Ryan%3BLee%2C+Larry%3BSlaven%2C+James%3BMartin%2C+Stephen&rft.aulast=Coffey&rft.aufirst=Christopher&rft.date=2012-01-01&rft.volume=9&rft.issue=11&rft.spage=670&rft.isbn=&rft.btitle=&rft.title=Journal+of+occupational+and+environmental+hygiene&rft.issn=1545-9632&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2013-02-22 N1 - Date created - 2012-09-28 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - The evolving epidemiology of HIV/AIDS AN - 1028032944; 16910160 AB - Following its recognition in 1981, the HIV/AIDS epidemic has evolved to become the greatest challenge in global health, with some 34 million persons living with HIV worldwide. Early epidemiologic studies identified the major transmission routes of the virus before it was discovered, and enabled the implementation of prevention strategies. Although the first identified cases were in MSM in the United States and western Europe, the greatest impact of the epidemic has been in sub-Saharan Africa, where most of the transmission occurs between heterosexuals. Nine countries in southern Africa account for less than 2% of the world's population but now they represent about one third of global HIV infections. Where broadly implemented, HIV screening of donated blood and antiretroviral treatment (ART) of pregnant women have been highly effective in preventing transfusion-associated and perinatally acquired HIV, respectively. Access to sterile equipment has also been a successful intervention for injection drug users. Prevention of sexual transmission has been more difficult. Perhaps the greatest challenge in terms of prevention has been in the global community of MSM in which HIV remains endemic at high prevalence. The most promising interventions are male circumcision for prevention of female-to-male transmission and use of ART to reduce infectiousness, but the extent to which these interventions can be brought to scale will determine their population-level impact. JF - AIDS AU - De Cock, KM AU - Jaffe, H W AU - Curran, J W AD - Centers for Disease Control and Prevention (MS D-69), 1600 Clifton Road, Atlanta, GA 30333, USA, kmd2@cdc.gov Y1 - 2012 PY - 2012 DA - 2012 SP - 1205 EP - 1213 VL - 26 IS - 10 SN - 0269-9370, 0269-9370 KW - Health & Safety Science Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - Acquired immune deficiency syndrome KW - Epidemics KW - antiretroviral therapy KW - Intervention KW - Europe KW - Infection KW - Drug abuse KW - Antiretroviral agents KW - Disease transmission KW - Pregnancy KW - Blood KW - USA KW - Prevention KW - Antiviral agents KW - Epidemiology KW - Human immunodeficiency virus KW - Africa KW - World population KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma KW - F 06910:Microorganisms & Parasites UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1028032944?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS&rft.atitle=The+evolving+epidemiology+of+HIV%2FAIDS&rft.au=De+Cock%2C+KM%3BJaffe%2C+H+W%3BCurran%2C+J+W&rft.aulast=De+Cock&rft.aufirst=KM&rft.date=2012-01-01&rft.volume=26&rft.issue=10&rft.spage=1205&rft.isbn=&rft.btitle=&rft.title=AIDS&rft.issn=02699370&rft_id=info:doi/10.1097%2FQAD.0b013e328354622a LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-07-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Blood; Acquired immune deficiency syndrome; Epidemics; Epidemiology; Antiviral agents; antiretroviral therapy; Drug abuse; Infection; Pregnancy; Disease transmission; Prevention; Human immunodeficiency virus; Intervention; Antiretroviral agents; World population; USA; Africa; Europe DO - http://dx.doi.org/10.1097/QAD.0b013e328354622a ER - TY - JOUR T1 - The Impact of State Preemption of Local Smoking Restrictions on Public Health Protections and Changes in Social Norms AN - 1022566644; 16809008 AB - Introduction . Preemption is a legislative or judicial arrangement in which a higher level of government precludes lower levels of government from exercising authority over a topic. In the area of smoke-free policy, preemption typically takes the form of a state law that prevents communities from adopting local smoking restrictions. Background . A broad consensus exists among tobacco control practitioners that preemption adversely impacts tobacco control efforts. This paper examines the effect of state provisions preempting local smoking restrictions in enclosed public places and workplaces. Methods . Multiple data sources were used to assess the impact of state preemptive laws on the proportion of indoor workers covered by smoke-free workplace policies and public support for smoke-free policies. We controlled for potential confounding variables. Results . State preemptive laws were associated with fewer local ordinances restricting smoking, a reduced level of worker protection from secondhand smoke, and reduced support for smoke-free policies among current smokers. Discussion . State preemptive laws have several effects that could impede progress in secondhand smoke protections and broader tobacco control efforts. Conclusion . Practitioners and advocates working on other public health issues should familiarize themselves with the benefits of local policy making and the potential impact of preemption. JF - Journal of Environmental and Public Health AU - Mowery, Paul D AU - Babb, Steve AU - Hobart, Robin AU - Tworek, Cindy AU - MacNeil, Allison AD - Biostatistics Inc., 228 East Wesley Road, NE, Atlanta, GA 30305, USA, pzm4@cdc.gov Y1 - 2012/01// PY - 2012 DA - Jan 2012 PB - Hindawi Publishing Corporation, P.O. Box 3079 Cuyahoga Falls OH 44223 United States VL - 2012 SN - 1687-9805, 1687-9805 KW - Environment Abstracts KW - Smoking KW - Passive smoking KW - Tobacco KW - Legislation KW - Public health KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1022566644?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+and+Public+Health&rft.atitle=The+Impact+of+State+Preemption+of+Local+Smoking+Restrictions+on+Public+Health+Protections+and+Changes+in+Social+Norms&rft.au=Mowery%2C+Paul+D%3BBabb%2C+Steve%3BHobart%2C+Robin%3BTworek%2C+Cindy%3BMacNeil%2C+Allison&rft.aulast=Mowery&rft.aufirst=Paul&rft.date=2012-01-01&rft.volume=2012&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+and+Public+Health&rft.issn=16879805&rft_id=info:doi/10.1155%2F2012%2F632629 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-06-01 N1 - Number of references - 39 N1 - Last updated - 2014-10-02 N1 - SubjectsTermNotLitGenreText - Smoking; Passive smoking; Tobacco; Legislation; Public health DO - http://dx.doi.org/10.1155/2012/632629 ER - TY - JOUR T1 - Avian Hosts of West Nile Virus in Puerto Rico AN - 1014102662; 16448431 AB - West Nile virus (WNV) ecology in neotropical ecosystems is poorly understood, and vertebrate hosts responsible for infecting mosquitoes remain unidentified throughout the Caribbean Basin. After a period of intense WNV transmission among sentinel chickens near Ceiba, Puerto Rico, we measured abundance of resident birds and species-specific prevalence of WNV infection. Taking the product of these measures indicates the relative number of WNV infections by species. Greater Antillean grackle (Quiscalus niger) accounted for the most WNV infections among birds in our 100-km super(2) study site. In urban habitats, the house sparrow (Passer domesticus) was frequently infected. Immature birds less than one year of age were more likely to have detectable WNV-reactive antibodies than older birds of the same species. JF - Vector Borne and Zoonotic Diseases AU - Komar, N AU - Bessoff, K AU - Diaz, A AU - Amador, M AU - Young, G AU - Seda, R AU - Perez, T AU - Hunsperger, E AD - Arboviral Diseases Branch (ADB), Division of Vector-Borne Diseases (DVBD), Centers for Disease Control and Prevention (CDC), 3150 Rampart Road, Fort Collins, CO 80521, USA, nkomar@cdc.gov Y1 - 2012/01// PY - 2012 DA - January 2012 SP - 47 EP - 54 VL - 12 IS - 1 SN - 1530-3667, 1530-3667 KW - ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Virology & AIDS Abstracts KW - Ceiba KW - Age KW - Abundance KW - Vectors KW - Basins KW - Hosts KW - Infection KW - Habitat KW - Quiscalus niger KW - Disease transmission KW - Public health KW - Passer domesticus KW - Antibodies KW - ASW, Caribbean Sea, Greater Antilles, Puerto Rico KW - Aquatic insects KW - West Nile virus KW - V 22410:Animal Diseases KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1014102662?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vector+Borne+and+Zoonotic+Diseases&rft.atitle=Avian+Hosts+of+West+Nile+Virus+in+Puerto+Rico&rft.au=Komar%2C+N%3BBessoff%2C+K%3BDiaz%2C+A%3BAmador%2C+M%3BYoung%2C+G%3BSeda%2C+R%3BPerez%2C+T%3BHunsperger%2C+E&rft.aulast=Komar&rft.aufirst=N&rft.date=2012-01-01&rft.volume=12&rft.issue=1&rft.spage=47&rft.isbn=&rft.btitle=&rft.title=Vector+Borne+and+Zoonotic+Diseases&rft.issn=15303667&rft_id=info:doi/10.1089%2Fvbz.2011.0609 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Antibodies; Hosts; Aquatic insects; Public health; Disease transmission; Age; Abundance; Basins; Vectors; Habitat; Infection; Passer domesticus; Ceiba; Quiscalus niger; West Nile virus; ASW, Caribbean Sea, Greater Antilles, Puerto Rico DO - http://dx.doi.org/10.1089/vbz.2011.0609 ER - TY - JOUR T1 - Group Medical Claims as a Source of Information on Worker Health and Potentially Work-Related Diseases AN - 915490387; 16152701 AB - Objective: To help address underrecognition of occupational illnesses and support planning of workplace health initiatives. Methods: Data from High-mark Inc., a health care insurer headquartered in Pittsburgh and Camp Hill, Pennsylvania, was used to calculate age and gender-adjusted rates of 15 diseases by industry and broad industry sector. Results: Significant industry differences in disease rates were observed, some corresponding to known differences in workplace risk factors. Conclusion: Group medical claims offer timely, relatively low cost, longitudinal data on rates of physician-diagnosed cases and costs of many diseases for large populations. Limitations of medical claims data include inaccuracies in industry coding, lack of occupation codes, and lack of key variables that affect health. Yet, some elevated industry rates suggest potential new targets for weltaess programs and evaluation of possible workplace health risks. JF - Journal of Occupational and Environmental Medicine AU - Bushnell, P T AU - Li, J AU - Landen, D AD - National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, 4676 Columbia Parkway, MS R17, Cincinnati, OH 45226, USA, PLB4@cdc.gov Y1 - 2011/12// PY - 2011 DA - Dec 2011 SP - 1430 EP - 1441 VL - 53 IS - 12 SN - 1076-2752, 1076-2752 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Age KW - Health care KW - Risk assessment KW - Risk factors KW - hills KW - USA, Pennsylvania KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/915490387?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Group+Medical+Claims+as+a+Source+of+Information+on+Worker+Health+and+Potentially+Work-Related+Diseases&rft.au=Bushnell%2C+P+T%3BLi%2C+J%3BLanden%2C+D&rft.aulast=Bushnell&rft.aufirst=P&rft.date=2011-12-01&rft.volume=53&rft.issue=12&rft.spage=1430&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e3182363bbe LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-01-01 N1 - Last updated - 2013-05-06 N1 - SubjectsTermNotLitGenreText - Risk assessment; hills; Age; Health care; Risk factors; USA, Pennsylvania DO - http://dx.doi.org/10.1097/JOM.0b013e3182363bbe ER - TY - JOUR T1 - ENHANCING HIV COMMUNICATION BETWEEN PARENTS AND CHILDREN: EFFICACY OF THE PARENTS MATTER! PROGRAM AN - 915485419; 16152471 AB - We examine efficacy of the Parents Matter! Program (PMP), a program to teach African-American parents of preadolescents sexual communication and HIV-prevention skills, through a multicenter, randomized control trial. A total of 1115 parent-child participants were randomized to one of three intervention arms (enhanced, brief, control). Percentages and 95% confidence intervals compare parents' perception of child readiness to learn about sexual issues, communication effectiveness, and dyad concordance from baseline to 12 months postintervention. Wilcoxon rank sum tests compare the changes in scores measuring communication content in HIV/AIDS, abstinence, and condom use. Compared to control, parents in the enhanced arm increased perception of child readiness to learn about sex (16% vs. 29%; p < .001), and a greater proportion of parent-child dyads reported concordant responses on communication topics: HIV/AIDS (15%, 95% CI = 8-21%; p < .001), abstinence (13%, 95% CI = 7-20%; p < .001), condoms (15%, 95% CI = 9-22%; p < .001). Increases in communication scores in HIV/AIDS, abstinence, and condom use were greater in the enhanced arm than control (p < 0.01). We conclude that the enhanced PMP can help parents educate children about HIV and prepare children to avoid sexual risk. JF - AIDS Education and Prevention AU - Miller, K S AU - Lin, CY AU - Poulsen, M N AU - Fasula, A AU - Wyckoff, S C AU - Forehand, R AU - Long, N AU - Armistead, L AD - Centers for Disease Control and Prevention, Center for Global Health, Division of Global HIV/AIDS, 1600 Clifton Rd., NE, Mailstop E-04, Atlanta, GA 30333, USA, kmiller@cdc.gov Y1 - 2011/12// PY - 2011 DA - Dec 2011 SP - 550 EP - 563 VL - 23 IS - 6 SN - 0899-9546, 0899-9546 KW - Risk Abstracts; Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - sexual behavior KW - Acquired immune deficiency syndrome KW - Communication KW - Children KW - Condoms KW - Education KW - Communications KW - Human immunodeficiency virus KW - Perception KW - condoms KW - Ethnic groups KW - Sex KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/915485419?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+Education+and+Prevention&rft.atitle=ENHANCING+HIV+COMMUNICATION+BETWEEN+PARENTS+AND+CHILDREN%3A+EFFICACY+OF+THE+PARENTS+MATTER%21+PROGRAM&rft.au=Miller%2C+K+S%3BLin%2C+CY%3BPoulsen%2C+M+N%3BFasula%2C+A%3BWyckoff%2C+S+C%3BForehand%2C+R%3BLong%2C+N%3BArmistead%2C+L&rft.aulast=Miller&rft.aufirst=K&rft.date=2011-12-01&rft.volume=23&rft.issue=6&rft.spage=550&rft.isbn=&rft.btitle=&rft.title=AIDS+Education+and+Prevention&rft.issn=08999546&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-01-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Condoms; Acquired immune deficiency syndrome; Perception; Communication; Children; Sex; sexual behavior; Education; Communications; Human immunodeficiency virus; condoms; Ethnic groups ER - TY - JOUR T1 - Method selection and adaptation for distributed monitoring of infectious diseases for syndromic surveillance AN - 911156846; 16085030 AB - Automated surveillance systems require statistical methods to recognize increases in visit counts that might indicate an outbreak. In prior work we presented methods to enhance the sensitivity of C2, a commonly used time series method. In this study, we compared the enhanced C2 method with five regression models. We used emergency department chief complaint data from US CDC BioSense surveillance system, aggregated by city (total of 206 hospitals, 16 cities) during 5/2008-4/2009. Data for six syndromes (asthma, gastrointestinal, nausea and vomiting, rash, respiratory, and influenza-like illness) was used and was stratified by mean count (1-19, 20-49, a[copy3450 per day) into 14 syndrome-count categories. We compared the sensitivity for detecting single-day artificially-added increases in syndrome counts. Four modifications of the C2 time series method, and five regression models (two linear and three Poisson), were tested. A constant alert rate of 1% was used for all methods. Among the regression models tested, we found that a Poisson model controlling for the logarithm of total visits (i.e., visits both meeting and not meeting a syndrome definition), day of week, and 14-day time period was best. Among 14 syndrome-count categories, time series and regression methods produced approximately the same sensitivity (<5% difference) in 6; in six categories, the regression method had higher sensitivity (range 6-14% improvement), and in two categories the time series method had higher sensitivity. When automated data are aggregated to the city level, a Poisson regression model that controls for total visits produces the best overall sensitivity for detecting artificially added visit counts. This improvement was achieved without increasing the alert rate, which was held constant at 1% for all methods. These findings will improve our ability to detect outbreaks in automated surveillance system data. JF - Journal of Biomedical Informatics AU - Xing, Jian AU - Burkom, Howard AU - Tokars, Jerome AD - Centers for Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA 30333, USA, jxing@cdc.gov Y1 - 2011/12// PY - 2011 DA - Dec 2011 SP - 1093 EP - 1101 PB - Elsevier B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 44 IS - 6 SN - 1532-0464, 1532-0464 KW - Biotechnology and Bioengineering Abstracts KW - Automated disease surveillance KW - Outbreak detection KW - Algorithm evaluation KW - Poisson regression KW - Data processing KW - Statistics KW - Adaptations KW - Vomiting KW - Asthma KW - Models KW - Exanthema KW - Infectious diseases KW - Regression analysis KW - Nausea KW - Bioinformatics KW - Hospitals KW - W 30960:Bioinformatics & Computer Applications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/911156846?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Biomedical+Informatics&rft.atitle=Method+selection+and+adaptation+for+distributed+monitoring+of+infectious+diseases+for+syndromic+surveillance&rft.au=Xing%2C+Jian%3BBurkom%2C+Howard%3BTokars%2C+Jerome&rft.aulast=Xing&rft.aufirst=Jian&rft.date=2011-12-01&rft.volume=44&rft.issue=6&rft.spage=1093&rft.isbn=&rft.btitle=&rft.title=Journal+of+Biomedical+Informatics&rft.issn=15320464&rft_id=info:doi/10.1016%2Fj.jbi.2011.08.012 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-12-01 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Exanthema; Vomiting; Adaptations; Statistics; Data processing; Infectious diseases; Regression analysis; Asthma; Nausea; Bioinformatics; Hospitals; Models DO - http://dx.doi.org/10.1016/j.jbi.2011.08.012 ER - TY - JOUR T1 - Toxicology, environmental health, and the "One Health" concept. AN - 908009983; 21818691 AB - The One Health concept promotes collaboration among veterinarians, physicians, scientists, and other professions to promote human, animal, and ecosystem health. One Health illustrates the interconnectedness and interdependence of human, animal, and ecosystem health. This concept has traditionally focused on zoonoses that are infectious diseases, not on chemical- or poison-related illnesses in animals and their relationship to the detection and prevention of human illness. The purpose of this article is to describe key experiences of scientists in the Health Studies Branch within the National Center for Environmental of Health of the Centers for Disease Control and Prevention in which the study of animal illness facilitated a public health investigation into an outbreak of chemical-associated human disease. The experiences highlight how utilizing the One Health approach may improve chemical-associated outbreak investigations and facilitate appropriate intervention strategies. An appropriate One Health approach in toxicology and environmental health in outbreak settings should include consideration of the common environments and food sources shared by humans and animals and consideration of the potential for contaminated animal products as food sources in human exposures. JF - Journal of medical toxicology : official journal of the American College of Medical Toxicology AU - Buttke, Danielle E AD - National Center for Environmental Health, Division of Environmental Hazards and Health Effects, Centers for Disease Control and Prevention, Chamblee, GA 30341, USA. iyk7@cdc.gov Y1 - 2011/12// PY - 2011 DA - December 2011 SP - 329 EP - 332 VL - 7 IS - 4 KW - Index Medicus KW - Animals KW - Zoonoses KW - Cooperative Behavior KW - Public Health KW - Disease Outbreaks -- prevention & control KW - Humans KW - Food Contamination KW - Ecosystem KW - Environmental Health KW - Toxicology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/908009983?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+medical+toxicology+%3A+official+journal+of+the+American+College+of+Medical+Toxicology&rft.atitle=Toxicology%2C+environmental+health%2C+and+the+%22One+Health%22+concept.&rft.au=Buttke%2C+Danielle+E&rft.aulast=Buttke&rft.aufirst=Danielle&rft.date=2011-12-01&rft.volume=7&rft.issue=4&rft.spage=329&rft.isbn=&rft.btitle=&rft.title=Journal+of+medical+toxicology+%3A+official+journal+of+the+American+College+of+Medical+Toxicology&rft.issn=1937-6995&rft_id=info:doi/10.1007%2Fs13181-011-0172-4 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-04-05 N1 - Date created - 2011-12-02 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Ther Drug Monit. 2001 Dec;23(6):698-708 [11802107] MMWR Morb Mortal Wkly Rep. 2004 Sep 3;53(34):790-3 [15343146] J Am Vet Med Assoc. 1974 Sep 1;165(5):437-9 [4425399] Environ Res. 1977 Feb;13(1):74-93 [191251] Ann N Y Acad Sci. 1979 May 31;320:684-702 [222195] Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2011 Mar;28(3):293-307 [21360375] Med Health R I. 2005 Jul;88(7):209 [16184822] Chemosphere. 2007 Oct;69(8):1295-304 [17617441] Sci Total Environ. 2008 Aug 25;402(1):1-8 [18501955] J Med Toxicol. 2008 Sep;4(3):197-200 [18821495] Comp Biochem Physiol C. 1984;79(1):193-204 [6149867] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1007/s13181-011-0172-4 ER - TY - JOUR T1 - Alterations in welding process voltage affect the generation of ultrafine particles, fume composition, and pulmonary toxicity. AN - 902331814; 21281223 AB - The goal was to determine if increasing welding voltage changes the physico-chemical properties of the fume and influences lung responses. Rats inhaled 40 mg/m³ (3 h/day × 3 days) of stainless steel (SS) welding fume generated at a standard voltage setting of 25 V (regular SS) or at a higher voltage (high voltage SS) of 30 V. Particle morphology, size and composition were characterized. Bronchoalveolar lavage was performed at different times after exposures to assess lung injury. Fumes collected from either of the welding conditions appeared as chain-like agglomerates of nanometer-sized primary particles. High voltage SS welding produced a greater number of ultrafine-sized particles. Fume generated by high voltage SS welding was higher in manganese. Pulmonary toxicity was more substantial and persisted longer after exposure to the regular SS fume. In summary, a modest raise in welding voltage affected fume size and elemental composition and altered the temporal lung toxicity profile. JF - Nanotoxicology AU - Antonini, James M AU - Keane, Michael AU - Chen, Bean T AU - Stone, Samuel AU - Roberts, Jenny R AU - Schwegler-Berry, Diane AU - Andrews, Ronnee N AU - Frazer, David G AU - Sriram, Krishnan AD - Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA. jga6@cdc.gov Y1 - 2011/12// PY - 2011 DA - December 2011 SP - 700 EP - 710 VL - 5 IS - 4 KW - Air Pollutants, Occupational KW - 0 KW - Stainless Steel KW - 12597-68-1 KW - Index Medicus KW - Rats KW - Animals KW - Rats, Sprague-Dawley KW - Bronchoalveolar Lavage Fluid -- chemistry KW - Particle Size KW - Inhalation Exposure KW - Male KW - Microscopy, Electron, Scanning KW - Welding -- methods KW - Stainless Steel -- toxicity KW - Lung -- cytology KW - Lung -- chemistry KW - Lung -- drug effects KW - Air Pollutants, Occupational -- toxicity KW - Stainless Steel -- chemistry KW - Nanoparticles -- toxicity KW - Nanoparticles -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/902331814?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Nanotoxicology&rft.atitle=Alterations+in+welding+process+voltage+affect+the+generation+of+ultrafine+particles%2C+fume+composition%2C+and+pulmonary+toxicity.&rft.au=Antonini%2C+James+M%3BKeane%2C+Michael%3BChen%2C+Bean+T%3BStone%2C+Samuel%3BRoberts%2C+Jenny+R%3BSchwegler-Berry%2C+Diane%3BAndrews%2C+Ronnee+N%3BFrazer%2C+David+G%3BSriram%2C+Krishnan&rft.aulast=Antonini&rft.aufirst=James&rft.date=2011-12-01&rft.volume=5&rft.issue=4&rft.spage=700&rft.isbn=&rft.btitle=&rft.title=Nanotoxicology&rft.issn=1743-5404&rft_id=info:doi/10.3109%2F17435390.2010.550695 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-05-30 N1 - Date created - 2011-11-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.3109/17435390.2010.550695 ER - TY - JOUR T1 - Measurement of airborne nanoparticle surface area using a filter-based gas adsorption method for inhalation toxicology experiments. AN - 902331808; 21261457 AB - Measurement of the surface area of airborne nanoparticles as administered to an experimental subject is critical for characterizing exposures during inhalation experiments. A filter-based surface area measurement methodology is described herein that allows for such determinations. Krypton gas adsorption was used to determine total particle surface area. Track-etched polycarbonate 0.4 μm pore filters were chosen as the collection substrate for metal oxide particles due to their highly reproducible surface areas and low background weights. The subject nanomaterials included two different batches of ultrafine TiO₂, TiO₂ nanorods, and SiO₂. The instrument detection limit for surface area was 200 cm² (0.02 m²). Ninety percent confidence interval estimates of method accuracy were 17.7-23.5% with a point estimate of 20.8%. The filter-based surface area measurement strategy is demonstrated to be a viable sampling and analysis methodology that provides much needed physical characterization information of particles as administered in an animal inhalation chamber. JF - Nanotoxicology AU - LeBuf, Ryan F AU - Stefaniak, Aleksandr B AU - Chen, Bean T AU - Frazer, David G AU - Virji, M Abbas AD - National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia 26505, USA. rlebouf@cdc.gov Y1 - 2011/12// PY - 2011 DA - December 2011 SP - 687 EP - 699 VL - 5 IS - 4 KW - Aerosols KW - 0 KW - titanium dioxide KW - 15FIX9V2JP KW - Silicon Dioxide KW - 7631-86-9 KW - Titanium KW - D1JT611TNE KW - Index Medicus KW - Microscopy, Electron, Transmission KW - Silicon Dioxide -- analysis KW - Titanium -- chemistry KW - Titanium -- analysis KW - Porosity KW - Linear Models KW - Toxicity Tests KW - Adsorption KW - Silicon Dioxide -- chemistry KW - Inhalation Exposure -- analysis KW - Nanoparticles -- analysis KW - Aerosols -- chemistry KW - Nanoparticles -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/902331808?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Nanotoxicology&rft.atitle=Measurement+of+airborne+nanoparticle+surface+area+using+a+filter-based+gas+adsorption+method+for+inhalation+toxicology+experiments.&rft.au=LeBuf%2C+Ryan+F%3BStefaniak%2C+Aleksandr+B%3BChen%2C+Bean+T%3BFrazer%2C+David+G%3BVirji%2C+M+Abbas&rft.aulast=LeBuf&rft.aufirst=Ryan&rft.date=2011-12-01&rft.volume=5&rft.issue=4&rft.spage=687&rft.isbn=&rft.btitle=&rft.title=Nanotoxicology&rft.issn=1743-5404&rft_id=info:doi/10.3109%2F17435390.2010.546951 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-05-30 N1 - Date created - 2011-11-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.3109/17435390.2010.546951 ER - TY - JOUR T1 - Effect of mother's migration on under-two mortality in Kenya AN - 1551629104; 20388020 AB - This study examines the effect of mothers' migration status controlling for other proximate factors (socio-economic, environmental and bio-demographic characteristics) on under two mortality in Kenya. Data used were drawn from 2003 Kenya Demographic Health Survey with focus on infants and children below two years in age. A total of 5949 infants and children born five years before the survey are used in the analysis. Cox proportional hazard model is used to assess the relative effect of the migration status (migrant or non-migrant) of the mother on survival rates controlling for other explanatory variables. The general results shows that children of migrant mothers especially those of urban-rural migrants face a higher mortality risk compared to those of non-migrant mothers. The results show that failure to account for migration may alter the estimation of urban-rural differentials in childhood mortality. JF - African Population Studies AU - Onyango, Emmanuel B Otieno AU - Khasakhala, Ann AU - Agwanda, A T AU - Kimani, Murungaru AU - K'Oyugi, Bonface AD - Center for Disease Control and Kenya Medical Research Institute (CDC/KEMRI) P.O.Box 1578-40100 (or P.O.Box 1648-40100) Kisumu, Kenya, eonyango@kemricdc.org Y1 - 2011/12// PY - 2011 DA - Dec 2011 SP - 543 EP - 555 PB - Union for African Population Studies, Immeuble Abdoulaye DIAW 2eme Etage Route des Mamelles Ouakam Dakar Senegal VL - 25 IS - 2 SN - 0850-5780, 0850-5780 KW - Health & Safety Science Abstracts; Risk Abstracts; Sustainability Science Abstracts KW - Risk assessment KW - Mortality KW - Age KW - Socioeconomics KW - Population studies KW - Survival KW - Children KW - Migration KW - Demography KW - Kenya KW - Risk factors KW - Africa KW - Migrants KW - Urban areas KW - Infants KW - M3 1010:Issues in Sustainable Development KW - R2 23060:Medical and environmental health KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1551629104?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=African+Population+Studies&rft.atitle=Effect+of+mother%27s+migration+on+under-two+mortality+in+Kenya&rft.au=Onyango%2C+Emmanuel+B+Otieno%3BKhasakhala%2C+Ann%3BAgwanda%2C+A+T%3BKimani%2C+Murungaru%3BK%27Oyugi%2C+Bonface&rft.aulast=Onyango&rft.aufirst=Emmanuel+B&rft.date=2011-12-01&rft.volume=25&rft.issue=2&rft.spage=543&rft.isbn=&rft.btitle=&rft.title=African+Population+Studies&rft.issn=08505780&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-08-01 N1 - Last updated - 2015-02-12 N1 - SubjectsTermNotLitGenreText - Risk assessment; Mortality; Age; Survival; Population studies; Socioeconomics; Children; Migration; Demography; Risk factors; Migrants; Infants; Urban areas; Kenya; Africa ER - TY - JOUR T1 - Measuring surface area of airborne titanium dioxide powder agglomerates: relationships between gas adsorption, diffusion and mobility-based methods AN - 1439736904; 18524374 AB - Inhalation toxicology studies generally use the Brunauer, Emmett, and Teller (BET) gas adsorption method to measure total surface area of particles whereas occupational exposures are more readily measured by real-time mobility-based surface areas or active surface area measured with diffusion charger-based instruments. Three surface area measurement methods were studied: filter-based inert gas adsorption (BET method), diffusion charging, and mobility-based methods. The goal of the project was to investigate and develop a correlation between the measurement methods. The experimental design consisted of measuring surface area in a series of five trials for each of two powder types, fine and ultrafine titanium dioxide with primary particle sizes of 440 and 20 nm, respectively, and two aerosol concentrations. Diffusion charger instruments tended to underestimate the total particle surface area measured by the BET, but were well correlated with mobility-based surface areas obtained from a scanning mobility particle sizer. Filter-based gas adsorption methods and diffusion charging methods provide different but valuable information on total and active surface areas of particles, respectively. Results indicate they should not be used as predictors of one another. JF - Journal of Nanoparticle Research AU - LeBouf, Ryan F AU - Ku, Bon Ki AU - Chen, Bean T AU - Frazer, David G AU - Cumpston, Jared L AU - Stefaniak, Aleksandr B AD - National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV, 26505, USA, astefaniak@cdc.gov Y1 - 2011/12// PY - 2011 DA - Dec 2011 SP - 7029 EP - 7039 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 13 IS - 12 SN - 1388-0764, 1388-0764 KW - Health & Safety Science Abstracts KW - Aerosols KW - Titanium dioxide KW - Mobility KW - Surface area KW - Adsorption KW - Diffusion KW - Particulates KW - Measuring instruments KW - Occupational exposure KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1439736904?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Nanoparticle+Research&rft.atitle=Measuring+surface+area+of+airborne+titanium+dioxide+powder+agglomerates%3A+relationships+between+gas+adsorption%2C+diffusion+and+mobility-based+methods&rft.au=LeBouf%2C+Ryan+F%3BKu%2C+Bon+Ki%3BChen%2C+Bean+T%3BFrazer%2C+David+G%3BCumpston%2C+Jared+L%3BStefaniak%2C+Aleksandr+B&rft.aulast=LeBouf&rft.aufirst=Ryan&rft.date=2011-12-01&rft.volume=13&rft.issue=12&rft.spage=7029&rft.isbn=&rft.btitle=&rft.title=Journal+of+Nanoparticle+Research&rft.issn=13880764&rft_id=info:doi/10.1007%2Fs11051-011-0616-4 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-10-01 N1 - Last updated - 2015-03-20 N1 - SubjectsTermNotLitGenreText - Aerosols; Titanium dioxide; Mobility; Surface area; Adsorption; Diffusion; Measuring instruments; Particulates; Occupational exposure DO - http://dx.doi.org/10.1007/s11051-011-0616-4 ER - TY - JOUR T1 - Update of the NIOSH life table analysis system: A person-years analysis program for the windows computing environment AN - 1017970867; 16691497 AB - Background Person-years analysis is a fundamental tool of occupational epidemiology. A life table analysis system (LTAS), previously developed by the National Institute for Occupational Safety and Health, was limited by its platform and analysis and reporting capabilities. We describe the updating of LTAS for the Windows operating system (LTAS.NET) with improved properties. Software Development Process A group of epidemiologists, programmers, and statisticians developed software, platform, and computing requirements. Statistical methods include the use of (indirectly) standardized mortality ratios, (directly) standardized rate ratios, confidence intervals, and P values based on the normal approximation and exact Poisson methods, and a trend estimator for linear exposure-response associations. Software Features We show examples using LTAS.NET to stratify and analyze multiple fixed and time-dependent variables. Data import, stratification, and reporting options are highly flexible. Users may export stratified data for Poisson regression modeling. Conclusions LTAS.NET incorporates improvements that will facilitate more complex person-years analysis of occupational cohort data. Am. J. Ind. Med. 54:915-924, 2011. ? 2011 Wiley Periodicals, Inc. JF - American Journal of Industrial Medicine AU - Schubauer-Berigan, Mary K AU - Hein, Misty J AU - Raudabaugh, William M AU - Ruder, Avima M AU - Silver, Sharon R AU - Spaeth, Steven AU - Steenland, Kyle AU - Petersen, Martin R AU - Waters, Kathleen M AD - Division of Surveillance, Hazard Evaluations, and Field Studies, Industrywide Studies Branch, National Institute for Occupational Safety and Health, Cincinnati, Ohio, zcg3@cdc.gov Y1 - 2011/12// PY - 2011 DA - Dec 2011 SP - 915 EP - 924 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 54 IS - 12 SN - 1097-0274, 1097-0274 KW - Health & Safety Science Abstracts KW - Computer programs KW - Mortality KW - exports KW - Dose-response effects KW - statisticians KW - Occupational safety KW - Standards KW - Stratification KW - imports KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1017970867?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Update+of+the+NIOSH+life+table+analysis+system%3A+A+person-years+analysis+program+for+the+windows+computing+environment&rft.au=Schubauer-Berigan%2C+Mary+K%3BHein%2C+Misty+J%3BRaudabaugh%2C+William+M%3BRuder%2C+Avima+M%3BSilver%2C+Sharon+R%3BSpaeth%2C+Steven%3BSteenland%2C+Kyle%3BPetersen%2C+Martin+R%3BWaters%2C+Kathleen+M&rft.aulast=Schubauer-Berigan&rft.aufirst=Mary&rft.date=2011-12-01&rft.volume=54&rft.issue=12&rft.spage=915&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=10970274&rft_id=info:doi/10.1002%2Fajim.20999 L2 - http://onlinelibrary.wiley.com/doi/10.1002/ajim.20999/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2013-06-28 N1 - SubjectsTermNotLitGenreText - Mortality; Computer programs; exports; statisticians; Dose-response effects; Occupational safety; Standards; Stratification; imports DO - http://dx.doi.org/10.1002/ajim.20999 ER - TY - CPAPER T1 - National Occupational Research Agenda Initiatives for Safety and Health in Manufacturing T2 - 2011 ASME International Mechanical Engineering Congress & Exposition (ASME 2011) AN - 1313040667; 6114260 JF - 2011 ASME International Mechanical Engineering Congress & Exposition (ASME 2011) AU - Lotz, Greg AU - Harris, James Y1 - 2011/11/11/ PY - 2011 DA - 2011 Nov 11 KW - Health and safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313040667?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2011+ASME+International+Mechanical+Engineering+Congress+%26+Exposition+%28ASME+2011%29&rft.atitle=National+Occupational+Research+Agenda+Initiatives+for+Safety+and+Health+in+Manufacturing&rft.au=Lotz%2C+Greg%3BHarris%2C+James&rft.aulast=Lotz&rft.aufirst=Greg&rft.date=2011-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2011+ASME+International+Mechanical+Engineering+Congress+%26+Exposition+%28ASME+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://www.asmeconferences.org/Congress2011/TechnicalProgramOverview.cfm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - JOUR T1 - Assessment of Occupational Cosmic Radiation Exposure of Flight Attendants Using Questionnaire Data AN - 968168138; 16120706 AB - Introduction: Female flight attendants may have a higher risk of breast and other cancers than the general population because of routine exposure to cosmic radiation. As part of a forthcoming study of breast and other cancer incidence, occupational cosmic radiation exposure of a cohort of female flight attendants was estimated. Methods: Questionnaire data were collected from living female cohort members who were formerly employed as flight attendants with Pan American World Airways. These data included airline at which the flight attendant was employed, assigned domicile, start and end dates for employment at domicile, and number of block hours and commuter segments flown per month. Questionnaire respondents were assigned daily absorbed and effective doses using a time-weighted dose rate specific to the domicile and/or work history era combined with self-reported work history information. Results: Completed work history questionnaires were received from 5898 living cohort members. Mean employment time as a flight attendant was 7.4 yr at Pan Am and 12 yr in total. Estimated mean annual effective dose from all sources of occupational cosmic radiation exposure was 2.5 plus or minus 1.0 mSv, with a mean career dose of 30 mSv. Discussion: Annual effective doses were similar to doses assessed for other flight attendant cohorts; however, questionnaire-based cumulative doses assessed in this study were on average higher than those assessed for other flight attendant cohorts using company-based records. The difference is attributed to the inclusion of dose from work at other airlines and commuter flights, which was made possible by using questionnaire data. JF - Aviation, Space, and Environmental Medicine AU - Anderson, Jeri L AU - Waters, Martha A AU - Hein, Misty J AU - Schubauer-Berigan, Mary K AU - Pinkerton, Lynne E AD - National Institute for Occupational Safety and Health, 4676 Columbia Pkwy , MS R-14, Cincinnati, OH 45226, jlanderson@cdc.gov Y1 - 2011/11// PY - 2011 DA - Nov 2011 SP - 1049 EP - 1054 PB - Aerospace Medical Association, 320 S. Henry St. Alexandria VA 22314-3579 United States VL - 82 IS - 11 SN - 0095-6562, 0095-6562 KW - Health & Safety Science Abstracts KW - careers KW - Historical account KW - employment KW - Dose-response effects KW - airlines KW - Cosmic radiation KW - Occupational exposure KW - Cancer KW - crew safety KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/968168138?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aviation%2C+Space%2C+and+Environmental+Medicine&rft.atitle=Assessment+of+Occupational+Cosmic+Radiation+Exposure+of+Flight+Attendants+Using+Questionnaire+Data&rft.au=Anderson%2C+Jeri+L%3BWaters%2C+Martha+A%3BHein%2C+Misty+J%3BSchubauer-Berigan%2C+Mary+K%3BPinkerton%2C+Lynne+E&rft.aulast=Anderson&rft.aufirst=Jeri&rft.date=2011-11-01&rft.volume=82&rft.issue=11&rft.spage=1049&rft.isbn=&rft.btitle=&rft.title=Aviation%2C+Space%2C+and+Environmental+Medicine&rft.issn=00956562&rft_id=info:doi/10.3357%2FASEM.3091.2011 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-01 N1 - Last updated - 2015-04-09 N1 - SubjectsTermNotLitGenreText - careers; Historical account; employment; airlines; Dose-response effects; Cosmic radiation; Cancer; Occupational exposure; crew safety DO - http://dx.doi.org/10.3357/ASEM.3091.2011 ER - TY - JOUR T1 - Molecular Detection of Bartonella Species in Ticks from Peru AN - 954656088; 16388378 AB - A total of 103 ticks, collected from canines, horses, donkeys, and snakes from Peru, were screened for the presence of Bartonella DNA by polymerase chain reaction analysis. Bartonella DNA was detected in two ticks using Bartonella 16S-23S intergenic spacer region primers and in an additional two ticks using Bartonella NADH dehydrogenase gamma subunit gene (nuoG) primers. Bartonella rochalimae Eremeeva et al., B. quintana Schmincke, and B. elizabethae Daly et al. DNA was detected in a Rhipicephalus sanguineus Latreille (Acari: Ixodidae) female tick removed from a dog and B. quintana DNA was present in a Dermacentor nitens Neumann (Acari: Ixodidae) pool of five larvae, one nymph, and one adult male tick collected from donkeys. This is the first study to report the detection of B. rochalimae, B. quintana, and B. elizabethae DNA in ticks from Peru. Further investigations must be performed to decipher the role ticks may play in the transmission of Bartonella species. JF - Journal of Medical Entomology AU - Billeter, Sarah A AU - Caceres, Abraham G AU - Gonzales-Hidalgo, James AU - Luna-Caypo, Deysi AU - Kosoy, Michael Y AD - Centers for Disease Control and Prevention, Division of Vector Borne Diseases, Fort Collins, CO., MKosoy@cdc.gov Y1 - 2011/11// PY - 2011 DA - Nov 2011 SP - 1257 EP - 1260 PB - Entomological Society of America, 9301 Annapolis Rd. Lanham MD 20706 United States VL - 48 IS - 6 SN - 0022-2585, 0022-2585 KW - Microbiology Abstracts B: Bacteriology; Entomology Abstracts KW - NADH dehydrogenase KW - Polymerase chain reaction KW - Primers KW - Spacer region KW - Bartonella KW - Ixodidae KW - Dermacentor KW - Acari KW - Rhipicephalus sanguineus KW - J 02410:Animal Diseases KW - Z 05350:Medical, Veterinary, and Agricultural Entomology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/954656088?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Medical+Entomology&rft.atitle=Molecular+Detection+of+Bartonella+Species+in+Ticks+from+Peru&rft.au=Billeter%2C+Sarah+A%3BCaceres%2C+Abraham+G%3BGonzales-Hidalgo%2C+James%3BLuna-Caypo%2C+Deysi%3BKosoy%2C+Michael+Y&rft.aulast=Billeter&rft.aufirst=Sarah&rft.date=2011-11-01&rft.volume=48&rft.issue=6&rft.spage=1257&rft.isbn=&rft.btitle=&rft.title=Journal+of+Medical+Entomology&rft.issn=00222585&rft_id=info:doi/10.1603%2FME10240 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Number of references - 26 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - Spacer region; NADH dehydrogenase; Polymerase chain reaction; Primers; Dermacentor; Ixodidae; Bartonella; Rhipicephalus sanguineus; Acari DO - http://dx.doi.org/10.1603/ME10240 ER - TY - JOUR T1 - Virulence of Pathogenic Coxiella burnetii Strains After Growth in the Absence of Host Cells AN - 918063140; 16154833 AB - Coxiella burnetii is a gram-negative bacterium that causes the zoonotic disease Q fever. Traditionally considered an obligate intracellular agent, the requirement to be grown in tissue culture cells, embryonated eggs, or animal hosts has made it difficult to isolate strains and perform genetic studies on C. burnetii. However, it was recently demonstrated that the attenuated Nine Mile Phase 2 (NM2) C. burnetii strain will grow axenically in acidified citrate cysteine medium (ACCM) in a 2.5% oxygen environment. The current study was undertaken to determine whether more virulent C. burnetii strains could be grown in ACCM, and whether virulence would be maintained after passage. The ACCM medium supported an similar to 1000-fold expansion of Nine Mile Phase 1 (NM1), NM2, M44, and Henzerling strains of C. burnetii, whereas the Priscilla (Q177) strain expanded only 100-fold, and the K strain (Q154) grew poorly in ACCM. To determine if passage in ACCM would maintain the virulence of C. burnetii, the NM1 strain was grown for up to 26 weekly passages in ACCM. C. burnetii maintained in ACCM for 5 or 8 passages maintained full virulence in a mouse model, but NM1 passaged for 23 or 26 times was somewhat attenuated. These data demonstrate that virulent strains of C. burnetii can be successfully passaged in ACCM; however, some strains can lose virulence after extended passage, and other strains grow poorly in this medium. The loss of virulence in axenic culture was associated with some truncation of lipopolysaccharide chains, suggesting a possible mechanism for attenuation. JF - Vector Borne and Zoonotic Diseases AU - Kersh, G J AU - Oliver, L D AU - Self, J S AU - Fitzpatrick, KA AU - Massung, R F AD - Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, 1600 Clifton Road, MS G-13, Atlanta, GA 30333, USA, gkersh@cdc.gov Y1 - 2011/11// PY - 2011 DA - Nov 2011 SP - 1433 EP - 1438 VL - 11 IS - 11 SN - 1530-3667, 1530-3667 KW - Microbiology Abstracts B: Bacteriology KW - Pure culture KW - Data processing KW - Animal models KW - Vectors KW - Tissue culture KW - Eggs KW - Virulence KW - Coxiella burnetii KW - Oxygen KW - Cysteine KW - Lipopolysaccharides KW - Q fever KW - Citric acid KW - J 02410:Animal Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/918063140?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vector+Borne+and+Zoonotic+Diseases&rft.atitle=Virulence+of+Pathogenic+Coxiella+burnetii+Strains+After+Growth+in+the+Absence+of+Host+Cells&rft.au=Kersh%2C+G+J%3BOliver%2C+L+D%3BSelf%2C+J+S%3BFitzpatrick%2C+KA%3BMassung%2C+R+F&rft.aulast=Kersh&rft.aufirst=G&rft.date=2011-11-01&rft.volume=11&rft.issue=11&rft.spage=1433&rft.isbn=&rft.btitle=&rft.title=Vector+Borne+and+Zoonotic+Diseases&rft.issn=15303667&rft_id=info:doi/10.1089%2Fvbz.2011.0670 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-01-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Pure culture; Virulence; Oxygen; Data processing; Cysteine; Animal models; Lipopolysaccharides; Vectors; Tissue culture; Q fever; Eggs; Citric acid; Coxiella burnetii DO - http://dx.doi.org/10.1089/vbz.2011.0670 ER - TY - JOUR T1 - Association of low-level blood lead and blood pressure in NHANES 1999-2006 AN - 912918725; 16000980 AB - This study investigated whether low blood-lead levels ( less than or equal to 10 mu g/dL) were associated with blood pressure (BP) outcomes. The authors analyzed data from National Health and Nutrition Examination Survey 1999-2006 and participants aged 20 years or older. Outcome variables were systolic and diastolic BP measurements, pulse pressure, and hypertension status. Multivariable linear and logistic regressions stratified by race/ethnicity and gender were performed. Blood lead levels (BLL) were significantly correlated with higher systolic BP among black men and women, but not white or Mexican-American participants. BLLs were significantly associated with higher diastolic BPs among white men and women and black men, whereas, a negative association was observed in Mexican-American men that had, also, a wider pulse pressure. Black men in the 90th percentile of blood lead distribution (BLL greater than or equal to 3.50 mu g/dL) compared to black men in the 10th percentile of blood lead distribution (BLL less than or equal to 0.7 mu g/dL) had a significant increase of risk of having hypertension (adjusted POR=2.69; 95% CI: 1.08-6.72). In addition, blood cadmium was significantly associated with hypertension and systolic and diastolic blood. This study found that, despite the continuous decline in blood lead in the U.S. population, lead exposure disparities among race and gender still exist. JF - Environmental Research AU - Scinicariello, Franco AU - Abadin, Henry G AU - Edward Murray, H AD - Centers for Disease Control and Prevention, Agency for Toxic Substances and Disease Registry, Division of Toxicology and Environmental Medicine, Atlanta, GA 30341, USA, fes6@cdc.gov Y1 - 2011/11// PY - 2011 DA - Nov 2011 SP - 1249 EP - 1257 PB - Elsevier B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 111 IS - 8 SN - 0013-9351, 0013-9351 KW - Toxicology Abstracts; Health & Safety Science Abstracts; Environment Abstracts KW - BLL KW - BMI KW - BP KW - NHANES KW - POR KW - Blood lead KW - Hypertension KW - Blood pressure KW - Blood cadmium KW - Data processing KW - blood pressure KW - Nutrition KW - Lead KW - Blood levels KW - USA KW - hypertension KW - Gender KW - Cadmium KW - Races KW - Ethnic groups KW - X 24360:Metals KW - H 12000:Epidemiology and Public Health KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/912918725?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Research&rft.atitle=Association+of+low-level+blood+lead+and+blood+pressure+in+NHANES+1999-2006&rft.au=Scinicariello%2C+Franco%3BAbadin%2C+Henry+G%3BEdward+Murray%2C+H&rft.aulast=Scinicariello&rft.aufirst=Franco&rft.date=2011-11-01&rft.volume=111&rft.issue=8&rft.spage=1249&rft.isbn=&rft.btitle=&rft.title=Environmental+Research&rft.issn=00139351&rft_id=info:doi/10.1016%2Fj.envres.2011.08.011 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-12-01 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Data processing; Cadmium; Nutrition; Ethnic groups; Blood pressure; Races; Lead; Hypertension; blood pressure; Gender; hypertension; Blood levels; USA DO - http://dx.doi.org/10.1016/j.envres.2011.08.011 ER - TY - JOUR T1 - The relationships between blood lead levels and serum follicle stimulating hormone and luteinizing hormone in the National Health and Nutrition Examination Survey 1999-2002 AN - 911155124; 15965247 AB - The relationships between blood lead levels and serum follicle stimulating hormone and luteinizing hormone were assessed in a nationally representative sample of women, 35-60 years old, from the National Health and Nutrition Examination Survey 1999-2002. The blood lead levels of the women ranged from 0.2 to 17.0 mu g/dL. The estimated geometric mean was 1.4 mu g/dL, and the estimated arithmetic mean was 1.6 mu g/dL. As the blood lead level increased, the concentration of serum follicle stimulating hormone increased in post-menopausal women, women who had both ovaries removed, and pre-menopausal women. The concentration of luteinizing hormone increased as blood lead level increased in post-menopausal women and women who had both ovaries removed. The lowest concentrations of blood lead at which a relationship was detected were 0.9 mu g/dL for follicle stimulating hormone and 3.2 mu g/dL for luteinizing hormone. Lead may act directly or indirectly at ovarian and non-ovarian sites to increase the concentrations of follicle stimulating hormone and luteinizing hormone. JF - Reproductive Toxicology AU - Krieg, Edward F AU - Feng, Huiling A AD - National Institute for Occupational Safety and Health, Robert A. Taft Laboratories, 4676 Columbia Parkway, MS C-22, Cincinnati, OH 45226, United States, erk3@cdc.gov Y1 - 2011/11// PY - 2011 DA - Nov 2011 SP - 277 EP - 285 PB - Elsevier B.V., Box 882 New York NY 10159 United States VL - 32 IS - 3 SN - 0890-6238, 0890-6238 KW - Environment Abstracts; Health & Safety Science Abstracts; Toxicology Abstracts KW - Follicles KW - Hormones KW - Nutrition KW - Lead KW - Blood levels KW - Mathematics KW - Blood KW - Luteinizing hormone KW - Ovaries KW - H 12000:Epidemiology and Public Health KW - X 24360:Metals KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/911155124?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Reproductive+Toxicology&rft.atitle=The+relationships+between+blood+lead+levels+and+serum+follicle+stimulating+hormone+and+luteinizing+hormone+in+the+National+Health+and+Nutrition+Examination+Survey+1999-2002&rft.au=Krieg%2C+Edward+F%3BFeng%2C+Huiling+A&rft.aulast=Krieg&rft.aufirst=Edward&rft.date=2011-11-01&rft.volume=32&rft.issue=3&rft.spage=277&rft.isbn=&rft.btitle=&rft.title=Reproductive+Toxicology&rft.issn=08906238&rft_id=info:doi/10.1016%2Fj.reprotox.2011.05.012 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-12-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Blood; Follicles; Luteinizing hormone; Ovaries; Nutrition; Hormones; Lead; Mathematics; Blood levels DO - http://dx.doi.org/10.1016/j.reprotox.2011.05.012 ER - TY - JOUR T1 - FEDERAL INTERAGENCY COMMUNICATION STRATEGIES FOR ADDRESSING RADIATION EMERGENCIES AND OTHER PUBLIC HEALTH CRISES AN - 907189208; 16044267 AB - Federal agencies have a variety of roles and responsibilities related to communicating with the public before, during, and after a radiological emergency. To better understand the various efforts currently underway, the Radiation Studies Branch of the Centers for Disease Control and Prevention convened a roundtable of representatives from federal agencies with responsibility for communicating with the public about radiation emergencies. Roundtable participants shared valuable information about efforts underway to develop information and messages for a variety of audiences and agreed that continued interagency coordination and dialogue about communication before, during, and after an event are needed. The group suggested several strategies for future collaborative efforts and indicated a desire to continue working together to develop and assess messages for radiological emergency preparedness and response. The group also recommended that more work be done to determine whether messages need to be packaged or tailored for specific special populations and suggested that more research be conducted to answer questions about specific audience/cultural needs around communicating radiation risks. Since this roundtable, attendees have continued to work together to develop and test messages for the public. JF - Health Physics AU - Miller, C W AU - McCurley, M C AD - Radiation Studies Branch, Division of Environmental Hazards and Health Effects, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway NE, MS:F58, Atlanta, GA 30341, USA, cmiller1@cdc.gov Y1 - 2011/11// PY - 2011 DA - Nov 2011 SP - 559 EP - 561 PB - Williams & Wilkins, 351 W. Camden St. Baltimore MD 21201 United States VL - 101 IS - 5 SN - 0017-9078, 0017-9078 KW - Risk Abstracts KW - Communications KW - Emergency preparedness KW - crises KW - prevention KW - disease control KW - culture KW - responsibility KW - Public health KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/907189208?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+Physics&rft.atitle=FEDERAL+INTERAGENCY+COMMUNICATION+STRATEGIES+FOR+ADDRESSING+RADIATION+EMERGENCIES+AND+OTHER+PUBLIC+HEALTH+CRISES&rft.au=Miller%2C+C+W%3BMcCurley%2C+M+C&rft.aulast=Miller&rft.aufirst=C&rft.date=2011-11-01&rft.volume=101&rft.issue=5&rft.spage=559&rft.isbn=&rft.btitle=&rft.title=Health+Physics&rft.issn=00179078&rft_id=info:doi/10.1097%2FHP.0b013e31822552d7 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2013-08-12 N1 - SubjectsTermNotLitGenreText - Communications; Emergency preparedness; crises; prevention; disease control; culture; Public health; responsibility DO - http://dx.doi.org/10.1097/HP.0b013e31822552d7 ER - TY - JOUR T1 - Detection of Swimming Pools by Geographic Object-based Image Analysis to Support West Nile Virus Control Efforts AN - 907184662; 16061920 AB - The recent economic crisis in United States has led to an increase in home foreclosures and subsequent abandonments. A by-product of this trend has been an associated rise in the number of neglected swimming pools, which provide new habitats for the larval stages of the Culex mosquito vectors of West Nile Virus (WNV) in urban and suburban environments, WNV has been major concern related to neglected swimming pools in California. Our research focused on using very high spatial resolution (VHR) satellite imagery and processing techniques, including image pansharpening, normalized difference water index, and geographic object-based image analysis (GEOBIA), to develop a geographic information system (GIS) database of swimming pool locations. This research demonstrated that GEOBIA with VHR imagery could produce a GIS database of swimming pools with the high accuracy of 94 percent. The analytic approach of this research is expected to economically facilitate the location of swimming pools for ground inspection and mosquito control. JF - Photogrammetric Engineering and Remote Sensing AU - Kim, M AU - Holt, J B AU - Eisen, R J AU - Padgett, K AU - Reisen, W K AU - Croft, J B AD - Emerging Investigations and Analytic Methods Branch, Division of Adult and Community Health, Centers for Disease Control and Prevention, 4770 Buford Highway., NE, MS K-67, Atlanta, GA 30341, USA, htj0@cdc.gov Y1 - 2011/11// PY - 2011 DA - November 2011 SP - 1169 EP - 1179 PB - American Society of Photogrammetry VL - 77 IS - 11 SN - 0099-1112, 0099-1112 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Virology & AIDS Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Swimming KW - Suburban environments KW - Byproducts KW - Remote sensing KW - Larvae KW - Image processing KW - Vectors KW - spatial discrimination KW - Pest control KW - Hosts KW - Habitat KW - Satellites KW - Public health KW - Culex KW - Databases KW - Satellite sensing KW - Economics KW - Swimming pools KW - USA, California KW - Geographic information systems KW - Aquatic insects KW - West Nile virus KW - V 22410:Animal Diseases KW - Q1 08485:Species interactions: pests and control KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/907184662?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Photogrammetric+Engineering+and+Remote+Sensing&rft.atitle=Detection+of+Swimming+Pools+by+Geographic+Object-based+Image+Analysis+to+Support+West+Nile+Virus+Control+Efforts&rft.au=Kim%2C+M%3BHolt%2C+J+B%3BEisen%2C+R+J%3BPadgett%2C+K%3BReisen%2C+W+K%3BCroft%2C+J+B&rft.aulast=Kim&rft.aufirst=M&rft.date=2011-11-01&rft.volume=77&rft.issue=11&rft.spage=1169&rft.isbn=&rft.btitle=&rft.title=Photogrammetric+Engineering+and+Remote+Sensing&rft.issn=00991112&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Satellite sensing; Swimming; Byproducts; Larvae; Remote sensing; Pest control; Hosts; Aquatic insects; Public health; Databases; Suburban environments; Economics; Vectors; Image processing; spatial discrimination; Swimming pools; Geographic information systems; Habitat; Satellites; Culex; West Nile virus; USA, California ER - TY - JOUR T1 - Intrauterine contraceptive insertion postabortion: a systematic review AN - 904494401; 15937618 AB - Background: This review was conducted to evaluate the evidence regarding the safety and effectiveness of intrauterine device (IUD) insertion immediately following spontaneous or induced abortion. Study Design: We searched MEDLINE databases for all articles (in all languages) published in peer-reviewed journals from January 1966 through March 2010 for evidence comparing immediate postabortion IUD insertion with either no IUD insertion, insertion at a different time, insertion following first-trimester compared with second-trimester abortion or copper IUD insertion compared with hormone-releasing IUD insertion postabortion. We used standard abstraction forms to summarize and assess the quality of the evidence. Results: The search strategy identified a total of 990 articles, of which 19 met our inclusion criteria for this review. Studies comparing immediate postabortion IUD insertion with no IUD insertion found that both groups experienced similar rates of pain and infection and a similar number of bleeding days, but one study reported that women with copper IUD insertion experienced a greater amount of bleeding than women without IUD insertion after abortion. Results from studies comparing immediate postabortion IUD insertion and insertion at a time not associated with pregnancy did not report differences between the two groups in the duration of bleeding, pain, expulsions or pelvic inflammatory disease (PID). One study however reported a greater amount of bleeding and another reported more removals for medical reasons among women with postabortion IUD insertion. Evidence from studies that examined immediate vs. delayed postabortion insertion reported minimal differences in bleeding, pain, expulsion and PID between groups. Studies comparing immediate IUD insertion after first- vs. second-trimester abortion reported no difference in removals for pain and bleeding, and an increased risk of expulsion among those women who had insertions after second-trimester abortion. In addition, women with insertions immediately after abortions occurring later in the first trimester had higher expulsion rates than those with insertions after early first-trimester abortions. Studies examining women using a copper IUD compared with a hormone-releasing IUD reported inconsistent results, with one paper reporting more bleeding days in the copper IUD group and another finding higher rates of removal for bleeding in the progesterone-releasing IUD group. Conclusion: Intrauterine device insertion immediately after abortion is not associated with an increased risk of adverse outcomes compared with use of other contraceptive methods or with no IUD insertion after abortion and compared with IUD insertion at times other than immediately after abortion. Intrauterine device expulsion rates, while generally low, were higher with insertions that occurred after later first-trimester abortion compared with after early first-trimester abortion and higher with IUD insertion after second-trimester abortion compared with after first-trimester abortion. JF - Contraception AU - Steenland, Maria W AU - Tepper, Naomi K AU - Curtis, Kathryn M AU - Kapp, Nathalie AD - Centers for Disease Control and Prevention, Atlanta, GA, 30341, USA, inu8@cdc.gov Y1 - 2011/11// PY - 2011 DA - Nov 2011 SP - 447 EP - 464 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 84 IS - 5 SN - 0010-7824, 0010-7824 KW - Risk Abstracts KW - Abortion KW - pain KW - Copper KW - contraceptives KW - Pregnancy KW - safety engineering KW - Reviews KW - infection KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/904494401?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Contraception&rft.atitle=Intrauterine+contraceptive+insertion+postabortion%3A+a+systematic+review&rft.au=Steenland%2C+Maria+W%3BTepper%2C+Naomi+K%3BCurtis%2C+Kathryn+M%3BKapp%2C+Nathalie&rft.aulast=Steenland&rft.aufirst=Maria&rft.date=2011-11-01&rft.volume=84&rft.issue=5&rft.spage=447&rft.isbn=&rft.btitle=&rft.title=Contraception&rft.issn=00107824&rft_id=info:doi/10.1016%2Fj.contraception.2011.03.007 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - safety engineering; Reviews; Abortion; infection; pain; Copper; Pregnancy; contraceptives DO - http://dx.doi.org/10.1016/j.contraception.2011.03.007 ER - TY - JOUR T1 - Maternal occupational pesticide exposure and risk of hypospadias in the national birth defects prevention study? AN - 1028021663; 16712185 AB - BACKGROUND Hypospadias is a common congenital malformation among men in which the urethral opening is ventrally displaced. Pesticide exposure has been suggested as a possible etiologic factor, but previous epidemiologic studies have produced inconsistent results. METHODS We used data from the National Birth Defects Prevention Study (NBDPS), a population-based case-control study, to examine maternal occupational exposure to fungicides, insecticides, and herbicides among 647 hypospadias case infants and 1496 unaffected male control infants with estimated delivery dates from October 1997 to December 2002. Periconceptional (1 month before conception through the first trimester of pregnancy) pesticide exposures were assigned by an expert rater, assisted by a job-exposure matrix (JEM), from a job history completed by mothers during a telephone interview. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated with multivariable logistic regression, and adjusted for relevant covariates. RESULTS Maternal periconceptional occupational exposure to any pesticides (yes/no) was not associated with an increased risk of hypospadias (OR = 0.78; 95% CI = 0.61-1.01). Maternal occupational periconceptional pesticide exposure type (insecticides, fungicides, and herbicides) and estimated quantity also showed no significantly increased risk of hypospadias and no evidence of a dose-response relationship; however, the estimated pesticide exposure levels in this population were low. CONCLUSION Using broad classes of insecticides, herbicides, and fungicides, we found no evidence that low intensity maternal periconceptional occupational pesticide exposure was a risk factor for hypospadias. Birth Defects Research (Part A) 2011. ? 2011 Wiley-Liss, Inc. JF - Birth Defects Research Part A: Clinical and Molecular Teratology AU - Rocheleau, Carissa M AU - Romitti, Paul A AU - Sanderson, Wayne T AU - Sun, Lixian AU - Lawson, Christina C AU - Waters, Martha A AU - Stewart, Patricia A AU - Olney, Richard S AU - Reefhuis, Jennita AD - Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, Iowa 52242, CRocheleau@cdc.gov Y1 - 2011/11// PY - 2011 DA - Nov 2011 SP - 927 EP - 936 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 91 IS - 11 SN - 1542-0760, 1542-0760 KW - Toxicology Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - Data processing KW - Herbicides KW - Pregnancy KW - Prevention KW - Insecticides KW - Risk factors KW - Dose-response effects KW - Pesticides KW - Fungicides KW - Congenital defects KW - Occupational exposure KW - Infants KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health KW - X 24330:Agrochemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1028021663?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Birth+Defects+Research+Part+A%3A+Clinical+and+Molecular+Teratology&rft.atitle=Maternal+occupational+pesticide+exposure+and+risk+of+hypospadias+in+the+national+birth+defects+prevention+study%3F&rft.au=Rocheleau%2C+Carissa+M%3BRomitti%2C+Paul+A%3BSanderson%2C+Wayne+T%3BSun%2C+Lixian%3BLawson%2C+Christina+C%3BWaters%2C+Martha+A%3BStewart%2C+Patricia+A%3BOlney%2C+Richard+S%3BReefhuis%2C+Jennita&rft.aulast=Rocheleau&rft.aufirst=Carissa&rft.date=2011-11-01&rft.volume=91&rft.issue=11&rft.spage=927&rft.isbn=&rft.btitle=&rft.title=Birth+Defects+Research+Part+A%3A+Clinical+and+Molecular+Teratology&rft.issn=15420760&rft_id=info:doi/10.1002%2Fbdra.22860 L2 - http://onlinelibrary.wiley.com/doi/10.1002/bdra.22860/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-07-01 N1 - Last updated - 2013-11-15 N1 - SubjectsTermNotLitGenreText - Data processing; Insecticides; Dose-response effects; Risk factors; Fungicides; Pesticides; Congenital defects; Herbicides; Occupational exposure; Pregnancy; Infants; Prevention DO - http://dx.doi.org/10.1002/bdra.22860 ER - TY - JOUR T1 - Chlamydia vaccines: recent developments and the role of adjuvants in future formulations AN - 1020836601; 16580034 AB - Bacteria of the genus Chlamydia cause a plethora of ocular, genital and respiratory diseases that continue to pose a considerable public health challenge worldwide. The major diseases are conjunctivitis and blinding trachoma, non-gonococcal urethritis, cervicitis, pelvic inflammatory disease, ectopic pregnancy, tubal factor infertility and interstitial pneumonia. The rampart asymptomatic infections prevent timely and effective antibiotic treatments, and quite often clinical presentation of sequelae is the first evidence of an infection. Besides, significant broad coverage in population screening and treatment is economically and logistically impractical, and mass education for public awareness has been ineffective. The current medical opinion is that an efficacious prophylactic vaccine is the best approach to protect humans from chlamydial infections. Unfortunately, a human vaccine has yet to be realized despite successful veterinary vaccines. Fortunately, recent advances in chlamydial immunobiology, cell biology, molecular pathogenesis, genomics, antigen discovery and animal models of infections are hastening progress toward an efficacious vaccine. Thus, it is established that Chlamydia immunity is mediated by T cells and a complementary antibody response, and several potential vaccine candidates have been identified. However, further advances are needed in effective vaccine delivery systems and safe potent adjuvants to boost and sustain immune responses for long-lasting protective immunity. This article focuses on the current status of human chlamydial vaccine research, specifically how application of new delivery systems and human compatible adjuvants could lead to a timely achievement of efficacious Chlamydia vaccines. The ranking of the candidate vaccine antigens for human vaccine development will await the availability of results from studies in which the antigens are tested by comparable experimental standards, such as antigen-adjuvant combination, route of delivery and possible toxicity. JF - Expert Review of Vaccines AU - Igietseme, Joseph U AU - Eko, Francis O AU - Black, Carolyn M AD - super(1)National Center for Emerging Zoonotic and Infectious Diseases, Centers for Disease Control and Prevention (CDC), 1600 Clifton Road, MailStop G-36, Atlanta, GA 30333, USA, jigietseme@cdc.gov Y1 - 2011/11// PY - 2011 DA - November 2011 SP - 1585 EP - 1596 PB - Future Science Group (FSG), Unitec House, 2 Albert Place London N3 1QB United Kingdom VL - 10 IS - 11 SN - 1476-0584, 1476-0584 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Microbiology Abstracts B: Bacteriology KW - adjuvant KW - Chlamydia KW - control KW - delivery KW - prevention KW - prophylactic KW - therapeutic KW - vaccine KW - Infertility KW - Animal models KW - Disease control KW - Antibiotics KW - Asymptomatic infection KW - Adjuvants KW - Interstitial environment KW - Toxicity tests KW - Non-specific urethritis KW - Cervicitis KW - Trachoma KW - Public health KW - Antigens KW - Lymphocytes T KW - Pelvic inflammatory disease KW - Cytology KW - genomics KW - Complications KW - Toxicity KW - Conjunctivitis KW - Antibody response KW - Immunity KW - Pregnancy KW - Education KW - Reviews KW - Vaccines KW - Pneumonia KW - Q1 08625:Non-edible products KW - J 02350:Immunology KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1020836601?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Expert+Review+of+Vaccines&rft.atitle=Chlamydia+vaccines%3A+recent+developments+and+the+role+of+adjuvants+in+future+formulations&rft.au=Igietseme%2C+Joseph+U%3BEko%2C+Francis+O%3BBlack%2C+Carolyn+M&rft.aulast=Igietseme&rft.aufirst=Joseph&rft.date=2011-11-01&rft.volume=10&rft.issue=11&rft.spage=1585&rft.isbn=&rft.btitle=&rft.title=Expert+Review+of+Vaccines&rft.issn=14760584&rft_id=info:doi/10.1586%2Ferv.11.139 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-06-01 N1 - Number of references - 122 N1 - Last updated - 2016-09-29 N1 - SubjectsTermNotLitGenreText - Education; Antigens; Disease control; Cytology; Interstitial environment; Immunity; Vaccines; Toxicity tests; Public health; Infertility; Complications; Animal models; Asymptomatic infection; Antibiotics; Antibody response; Adjuvants; Conjunctivitis; Toxicity; Trachoma; Cervicitis; Non-specific urethritis; Pregnancy; Reviews; Lymphocytes T; Pelvic inflammatory disease; genomics; Pneumonia; Chlamydia DO - http://dx.doi.org/10.1586/erv.11.139 ER - TY - JOUR T1 - Prevalence of beta-lactam nonsusceptible Gram-negative bacilli and use and interpretation of current susceptibility breakpoints: a survey of infectious disease physicians AN - 1014105667; 15892580 AB - Beta-lactam-resistant Enterobacteriaceae represent an important public health problem; however, questions exist about their prevalence and the impact of recent breakpoint changes on clinical practice. We surveyed infectious disease physicians to better understand these issues. Many reported encountering resistant Enterobacteriaceae; respondents generally favored a more conservative interpretation of antimicrobial susceptibility results. JF - Diagnostic Microbiology and Infectious Disease AU - Kallen, Alexander J AU - Beekmann, Susan E AU - Limbago, Brandi AU - Lentnek, Arnold L AU - Polgreen, Philip M AU - Patel, Jean AU - Srinivasan, Arjun AD - Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA, AKallen@cdc.gov Y1 - 2011/11// PY - 2011 DA - November 2011 SP - 316 EP - 319 PB - Elsevier B.V., Box 882 New York NY 10159 United States VL - 71 IS - 3 SN - 0732-8893, 0732-8893 KW - Microbiology Abstracts B: Bacteriology KW - Gram-negative bacilli KW - Antimicrobial susceptibility KW - Antimicrobial resistance KW - Breakpoints KW - Infectious diseases KW - Enterobacteriaceae KW - Public health KW - Antimicrobial agents KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1014105667?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Diagnostic+Microbiology+and+Infectious+Disease&rft.atitle=Prevalence+of+beta-lactam+nonsusceptible+Gram-negative+bacilli+and+use+and+interpretation+of+current+susceptibility+breakpoints%3A+a+survey+of+infectious+disease+physicians&rft.au=Kallen%2C+Alexander+J%3BBeekmann%2C+Susan+E%3BLimbago%2C+Brandi%3BLentnek%2C+Arnold+L%3BPolgreen%2C+Philip+M%3BPatel%2C+Jean%3BSrinivasan%2C+Arjun&rft.aulast=Kallen&rft.aufirst=Alexander&rft.date=2011-11-01&rft.volume=71&rft.issue=3&rft.spage=316&rft.isbn=&rft.btitle=&rft.title=Diagnostic+Microbiology+and+Infectious+Disease&rft.issn=07328893&rft_id=info:doi/10.1016%2Fj.diagmicrobio.2011.07.013 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2016-07-07 N1 - SubjectsTermNotLitGenreText - Breakpoints; Infectious diseases; Gram-negative bacilli; Antimicrobial agents; Public health; Enterobacteriaceae DO - http://dx.doi.org/10.1016/j.diagmicrobio.2011.07.013 ER - TY - CPAPER T1 - CDC Prevention Research Centers' Policy and Environmental Changes to Promote Healthy Communities T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1313013008; 6048934 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Stringer, Kate AU - Spadaro, Antonia AU - Grunbaum, Jo AU - Simoes, Eduardo Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Environmental changes KW - prevention KW - Policies KW - Climatic changes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313013008?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=CDC+Prevention+Research+Centers%27+Policy+and+Environmental+Changes+to+Promote+Healthy+Communities&rft.au=Stringer%2C+Kate%3BSpadaro%2C+Antonia%3BGrunbaum%2C+Jo%3BSimoes%2C+Eduardo&rft.aulast=Stringer&rft.aufirst=Kate&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Assessing progress rowards the national health objectives: Healthy People 2010 Final Review and Healthy People 2020 T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1313007061; 6048906 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Hines, Rebecca Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Reviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313007061?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Assessing+progress+rowards+the+national+health+objectives%3A+Healthy+People+2010+Final+Review+and+Healthy+People+2020&rft.au=Hines%2C+Rebecca&rft.aulast=Hines&rft.aufirst=Rebecca&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Faces of Black Lung T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312998673; 6050323 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Wolfe, Anita AU - Petsonk, Edward AU - Urban, Charles Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Lung KW - Black lung UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312998673?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Faces+of+Black+Lung&rft.au=Wolfe%2C+Anita%3BPetsonk%2C+Edward%3BUrban%2C+Charles&rft.aulast=Wolfe&rft.aufirst=Anita&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Evaluation of large jail STD screening programs in the US, 2008-2009 T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312997678; 6051294 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Doshi, Sonal AU - Kent, Charlotte AU - Geter, Angelica Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Sexually-transmitted diseases KW - prisons KW - Screening UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312997678?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Evaluation+of+large+jail+STD+screening+programs+in+the+US%2C+2008-2009&rft.au=Doshi%2C+Sonal%3BKent%2C+Charlotte%3BGeter%2C+Angelica&rft.aulast=Doshi&rft.aufirst=Sonal&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - A Plan for Action T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312995731; 6048202 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Nichols, Phyllis Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Public health KW - Nutrition KW - Sports KW - Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312995731?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=A+Plan+for+Action&rft.au=Nichols%2C+Phyllis&rft.aulast=Nichols&rft.aufirst=Phyllis&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Individual, Household, and Neighborhood Predictors of Daily Physical Activity among American Indian and Alaskan Native Children and Adolescents T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312984495; 6050524 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Barradas, Danielle AU - Njai, Rashid Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - households KW - physical activity KW - Adolescents KW - Children KW - Ethnic groups KW - Physical activity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312984495?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Individual%2C+Household%2C+and+Neighborhood+Predictors+of+Daily+Physical+Activity+among+American+Indian+and+Alaskan+Native+Children+and+Adolescents&rft.au=Barradas%2C+Danielle%3BNjai%2C+Rashid&rft.aulast=Barradas&rft.aufirst=Danielle&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Association of family and healthcare provider opinion with a mother's decision not to breastfeed -- Infant Feeding Practices II Study T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312981674; 6051746 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Odom, Erika AU - Li, Ruowei AU - Scanlon, Kelley AU - Grummer-Strawn, Laurence AU - Perrine, Cria Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - feeding KW - Infants KW - Medical personnel KW - Feeding UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312981674?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Association+of+family+and+healthcare+provider+opinion+with+a+mother%27s+decision+not+to+breastfeed+--+Infant+Feeding+Practices+II+Study&rft.au=Odom%2C+Erika%3BLi%2C+Ruowei%3BScanlon%2C+Kelley%3BGrummer-Strawn%2C+Laurence%3BPerrine%2C+Cria&rft.aulast=Odom&rft.aufirst=Erika&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - School-based fitness testing for large-scale surveillance of student fitness levels and childhood obesity T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312965626; 6051388 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Nihiser, Allison AU - Lee, Sarah AU - Morrow, James AU - Freedman, David Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - obesity KW - Children KW - Fitness KW - Obesity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312965626?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=School-based+fitness+testing+for+large-scale+surveillance+of+student+fitness+levels+and+childhood+obesity&rft.au=Nihiser%2C+Allison%3BLee%2C+Sarah%3BMorrow%2C+James%3BFreedman%2C+David&rft.aulast=Nihiser&rft.aufirst=Allison&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - BMI Cut-points in the CDC growth charts and in Fitnessgram T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312965543; 6051386 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Freedman, David Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - body mass KW - Growth UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312965543?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=BMI+Cut-points+in+the+CDC+growth+charts+and+in+Fitnessgram&rft.au=Freedman%2C+David&rft.aulast=Freedman&rft.aufirst=David&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Women at high risk for diabetes: Improving data, access and quality of care T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312960846; 6049176 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Owens-Gary, Michelle Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - diabetes mellitus KW - Data processing KW - Diabetes mellitus KW - Risk factors UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312960846?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Women+at+high+risk+for+diabetes%3A+Improving+data%2C+access+and+quality+of+care&rft.au=Owens-Gary%2C+Michelle&rft.aulast=Owens-Gary&rft.aufirst=Michelle&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - National Health Care Surveys T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312960055; 6048189 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Brown, Clarice Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Health care UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312960055?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=National+Health+Care+Surveys&rft.au=Brown%2C+Clarice&rft.aulast=Brown&rft.aufirst=Clarice&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - National Health and Nutrition Examination Survey, Part II T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312960022; 6048188 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Hirsch, Rosemarie Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Nutrition UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312960022?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=National+Health+and+Nutrition+Examination+Survey%2C+Part+II&rft.au=Hirsch%2C+Rosemarie&rft.aulast=Hirsch&rft.aufirst=Rosemarie&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - National Health and Nutrition Examination Survey, Part I T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312959990; 6048187 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Hirsch, Rosemarie Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Nutrition UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312959990?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=National+Health+and+Nutrition+Examination+Survey%2C+Part+I&rft.au=Hirsch%2C+Rosemarie&rft.aulast=Hirsch&rft.aufirst=Rosemarie&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - A call to action: Innovative national activities to address osteoarthritis T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312945020; 6051101 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Baker, Tai AU - Odom, Erica AU - Waterman, Mary AU - White, Patience Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Innovations KW - Osteoarthritis KW - Vocalization behavior UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312945020?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=A+call+to+action%3A+Innovative+national+activities+to+address+osteoarthritis&rft.au=Baker%2C+Tai%3BOdom%2C+Erica%3BWaterman%2C+Mary%3BWhite%2C+Patience&rft.aulast=Baker&rft.aufirst=Tai&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Sustaining Policy, Systems, and Environmental Change Strategies T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312936054; 6048205 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Nichols, Phyllis Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Environmental changes KW - Policies KW - Climatic changes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312936054?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Sustaining+Policy%2C+Systems%2C+and+Environmental+Change+Strategies&rft.au=Nichols%2C+Phyllis&rft.aulast=Nichols&rft.aufirst=Phyllis&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Health Literacy and Healthy Homes: A Call to Action T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312903586; 6050387 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Walker, Nikki Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Vocalization behavior UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312903586?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Health+Literacy+and+Healthy+Homes%3A+A+Call+to+Action&rft.au=Walker%2C+Nikki&rft.aulast=Walker&rft.aufirst=Nikki&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Rationale for standardizing the recommended fluoridation level T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312900577; 6049428 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Beltran, Eugenio Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Fluoridation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312900577?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Rationale+for+standardizing+the+recommended+fluoridation+level&rft.au=Beltran%2C+Eugenio&rft.aulast=Beltran&rft.aufirst=Eugenio&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - JOUR T1 - A Pre-Pandemic Outbreak of Triple-Reassortant Swine Influenza Virus Infection Among University Students, South Dakota, 2008 AN - 1635014714; 20933553 AB - Background. After identifying a student with triple-reassortant swine influenza virus (SIV) infection and pig exposure at a livestock event, we investigated whether others were infected and if human-to-human transmission occurred. Methods. We conducted a cohort study and serosurvey among persons exposed to (1) event pigs, (2) other pigs, (3) the index case, and (4) persons without pig or index case exposure. Confirmed cases had respiratory specimens positive for SIV within 2 weeks of the index case's illness. Probable and suspected cases had illness and (1) exposure to any pig or (2) contact with a confirmed case preceding illness. Probable cases were seropositive. Suspected cases did not give serum samples. Results. Of 99 event pig-exposed students, 72 (73%) participated in the investigation, and 42 (42%) provided serum samples, of whom 17 (40%) were seropositive and 5 (12%) met case criteria. Of 9 students exposed to other pigs, 2 (22%) were seropositive. Of 8 index case-exposed persons and 10 without exposures, none were seropositive. Pig-exposed persons were more likely to be seropositive than persons without pig exposure (37% vs 0%, P < .01). Conclusions. We identified an outbreak of human SIV infection likely associated with a livestock event; there was no evidence of human-to-human transmission. JF - Journal of Infectious Diseases AU - Dawood, Fatimah S AU - Dong, Libo AU - Liu, Feng AU - Blau, Dianna M AU - Peebles, Patrick J AU - Lu, Xiuhua AU - Wagers, Lori AU - Oakland, Brett AU - Zielenski, Michael AU - Daly, Russell AD - Influenza Division; Epidemic Intelligence Service Officer assigned to the Influenza Division, Centers for Disease Control and Prevention, 1600 Clifton Rd, MS A-32, Atlanta, GA 30333, fdawood@cdc.gov Y1 - 2011/10/15/ PY - 2011 DA - 2011 Oct 15 SP - 1165 EP - 1171 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 204 IS - 8 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - USA, South Dakota KW - Influenza KW - Infectious diseases KW - Swine influenza KW - Outbreaks KW - Infection KW - Swine influenza virus KW - Disease transmission KW - Livestock KW - V 22360:AIDS and HIV KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1635014714?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=A+Pre-Pandemic+Outbreak+of+Triple-Reassortant+Swine+Influenza+Virus+Infection+Among+University+Students%2C+South+Dakota%2C+2008&rft.au=Dawood%2C+Fatimah+S%3BDong%2C+Libo%3BLiu%2C+Feng%3BBlau%2C+Dianna+M%3BPeebles%2C+Patrick+J%3BLu%2C+Xiuhua%3BWagers%2C+Lori%3BOakland%2C+Brett%3BZielenski%2C+Michael%3BDaly%2C+Russell&rft.aulast=Dawood&rft.aufirst=Fatimah&rft.date=2011-10-15&rft.volume=204&rft.issue=8&rft.spage=1165&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjir502 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-12-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Swine influenza; Infection; Livestock; Disease transmission; Influenza; Infectious diseases; Outbreaks; Swine influenza virus; USA, South Dakota DO - http://dx.doi.org/10.1093/infdis/jir502 ER - TY - JOUR T1 - Periodic Spirometry in Occupational Setting Improving Quality, Accuracy, and Precision AN - 912920591; 16044336 AB - Objective: Effectiveness of periodic spirometry in medical monitoring depends on spirometry quality. We describe an intervention on spirometry quality and its impact on accuracy and precision of longitudinal measurements. Methods: The intervention was conducted from 2005 to 2010 in a monitoring program involving approximately 2500 firefighters. Intervention supported adherence to 2005 American Thoracic Society/European Respiratory Society recommendations through monitoring of spirometry quality and longitudinal data precision, technician training, change of spirometer, and quality control. Results: The percentage of forced vital capacity tests meeting the American Thoracic Society/European Respiratory Society criteria increased from 60% to 95% and the mean longitudinal forced expiratory volume in 1 second within-person variation decreased from 6% to 4%. The increased accuracy and precision of measurements and estimated rates of forced expiratory volume in 1 second decline were statistically significant. Conclusion: Monitoring of quality and data precision helped to recognize the need for intervention. The intervention improved accuracy and precision of spirometry measurements and their usefulness. JF - Journal of Occupational and Environmental Medicine AU - Hnizdo, E AU - Hakobyan, A AU - Fleming, J L AU - Beeckman-Wagner, L-A AD - Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, 1095 Willowdale Rd, Morgantown, WV 26505, USA, ehnizdo@cdc.gov Y1 - 2011/10// PY - 2011 DA - Oct 2011 SP - 1205 EP - 1209 VL - 53 IS - 10 SN - 1076-2752, 1076-2752 KW - Health & Safety Science Abstracts KW - firefighter services KW - Training KW - intervention KW - Quality control KW - technicians KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/912920591?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Periodic+Spirometry+in+Occupational+Setting+Improving+Quality%2C+Accuracy%2C+and+Precision&rft.au=Hnizdo%2C+E%3BHakobyan%2C+A%3BFleming%2C+J+L%3BBeeckman-Wagner%2C+L-A&rft.aulast=Hnizdo&rft.aufirst=E&rft.date=2011-10-01&rft.volume=53&rft.issue=10&rft.spage=1205&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e31823078b8 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-12-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - firefighter services; Training; Quality control; intervention; technicians DO - http://dx.doi.org/10.1097/JOM.0b013e31823078b8 ER - TY - JOUR T1 - Bacteriologic monitoring of multidrug-resistant tuberculosis patients in five DOTS-Plus pilot projects AN - 907183269; 15892348 AB - BACKGROUND: Multidrug-resistant tuberculosis programs in DOTS-Plus pilot sites in five countries. OBJECTIVES: To calculate sputum conversion time and its relationship to treatment outcome, document the frequency of culture reversions and examine concordance of smear and culture to assess the potential consequences of monitoring by smear microscopy alone. DESIGN: Retrospective cohort analysis of 1926 patients receiving individualized, second-line therapy. RESULTS: Among 1385 sputum culture-positive cases at baseline, 1146 (83%) experienced at least one culture conversion during treatment. Conversion, however, was not sustained in all patients: 201 (15%) experienced initial culture conversion and at least one subsequent culture reversion to positive; 1064 (77%) achieved sustained culture conversion. Median time to culture conversion was 3 months. Among 206 patients whose final conversion occurred 7-18 months after the initiation of therapy, 71% were cured or had completed treatment. CONCLUSIONS: Prolonged treatment for patients with delayed conversion may be beneficial, as 71% of late converters still achieved cure or completed treatment. This has implications for programs with defined end points for treatment failure. The interval between first and final conversion among patients whose initial conversion is not sustained raises concern with respect to the ongoing debate regarding duration of treatment and the definition of cure. JF - International Journal of Tuberculosis and Lung Disease AU - Gammino, V M AU - Taylor, AB AU - Rich, M L AU - Bayona, J AU - Becerra, M C AU - Bonilla, C AU - Gelmanova, I AU - Hollo, V AU - Jaramillo, E AU - Keshavjee, S AU - Leimane, V AU - Mitnick, C D AU - Quelapio, MID AU - Riektsina, V AD - Division of Tuberculosis Elimination, US Centers for Disease Control, 1600 Clifton Rd NE, MS E-10 Atlanta, Georgia 30333, USA, vmg0@cdc.gov Y1 - 2011/10// PY - 2011 DA - Oct 2011 SP - 1315 EP - 1322 PB - International Union Against Tuberculosis and Lung Disease VL - 15 IS - 10 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology KW - Bacteria KW - Mycobacterium KW - Drug resistance KW - Microscopy KW - Lung diseases KW - Reversion KW - Tuberculosis KW - Sputum KW - A 01490:Miscellaneous KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/907183269?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Bacteriologic+monitoring+of+multidrug-resistant+tuberculosis+patients+in+five+DOTS-Plus+pilot+projects&rft.au=Gammino%2C+V+M%3BTaylor%2C+AB%3BRich%2C+M+L%3BBayona%2C+J%3BBecerra%2C+M+C%3BBonilla%2C+C%3BGelmanova%2C+I%3BHollo%2C+V%3BJaramillo%2C+E%3BKeshavjee%2C+S%3BLeimane%2C+V%3BMitnick%2C+C+D%3BQuelapio%2C+MID%3BRiektsina%2C+V&rft.aulast=Gammino&rft.aufirst=V&rft.date=2011-10-01&rft.volume=15&rft.issue=10&rft.spage=1315&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Drug resistance; Microscopy; Lung diseases; Reversion; Tuberculosis; Sputum; Bacteria; Mycobacterium ER - TY - JOUR T1 - Efficacy of Structural-Level Condom Distribution Interventions: A Meta-Analysis of U.S. and International Studies, 1998-2007 AN - 902347015; 15837886 AB - This systematic review examines the overall efficacy of U.S. and international-based structural-level condom distribution interventions (SLCDIs) on HIV risk behaviors and STIs and identifies factors associated with intervention efficacy. A comprehensive literature search of studies published from January 1988 through September 2007 yielded 21 relevant studies. Significant intervention effects were found for the following outcomes: condom use, condom acquisition/condom carrying, delayed sexual initiation among youth, and reduced incident STIs. The stratified analyses for condom use indicated that interventions were efficacious for various groups (e.g., youth, adults, males, commercial sex workers, clinic populations, and populations in areas with high STI incidence). Interventions increasing the availability of or accessibility to condoms or including additional individual, small-group or community-level components along with condom distribution were shown to be efficacious in increasing condom use behaviors. This review suggests that SLCDIs provide an efficacious means of HIV/STI prevention. JF - AIDS and Behavior AU - Charania, Mahnaz R AU - Crepaz, Nicole AU - Guenther-Gray, Carolyn AU - Henny, Kirk AU - Liau, Adrian AU - Willis, Leigh A AU - Lyles, Cynthia M AD - Prevention Research Branch, Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road, Mailstop E-37, Atlanta, GA, 30333, USA, MCharania@cdc.gov MCharania@cdc.gov MCharania@cdc.gov MCharania@cdc.gov MCharania@cdc.gov MCharania@cdc.gov Y1 - 2011/10// PY - 2011 DA - Oct 2011 SP - 1283 EP - 1297 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 15 IS - 7 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - sexual behavior KW - Acquired immune deficiency syndrome KW - Prostitution KW - Condoms KW - prostitution KW - USA KW - Human immunodeficiency virus KW - intervention KW - Reviews KW - condoms KW - prevention KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/902347015?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Efficacy+of+Structural-Level+Condom+Distribution+Interventions%3A+A+Meta-Analysis+of+U.S.+and+International+Studies%2C+1998-2007&rft.au=Charania%2C+Mahnaz+R%3BCrepaz%2C+Nicole%3BGuenther-Gray%2C+Carolyn%3BHenny%2C+Kirk%3BLiau%2C+Adrian%3BWillis%2C+Leigh+A%3BLyles%2C+Cynthia+M&rft.aulast=Charania&rft.aufirst=Mahnaz&rft.date=2011-10-01&rft.volume=15&rft.issue=7&rft.spage=1283&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-010-9812-y LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - Condoms; Reviews; Prostitution; sexual behavior; prostitution; Acquired immune deficiency syndrome; Human immunodeficiency virus; intervention; prevention; condoms; USA DO - http://dx.doi.org/10.1007/s10461-010-9812-y ER - TY - JOUR T1 - Influence of light on aryl hydrocarbon receptor signaling and consequences in drug metabolism, physiology and disease. AN - 890678166; 21883026 AB - A key to understanding the biological function(s) of the aryl hydrocarbon receptor (AHR) - a xenobiotic-activated receptor - is to identify its endogenous ligand(s). The discovery of a tryptophan photoproduct 6-formylindolo[3,2-b]carbazole (FICZ) as an endogenous, high affinity agonist of AHR filled this knowledge gap in the context of skin physiology and pathology in response to light and opened several new directions for research on AHR. This paper reviews major developments in the study of light-elicited AHR signaling and its impact on drug metabolism, skin physiology and disease with a focus on the identification of AHR ligands from Trp photoproducts and the AHR-mediated UV response. This review consists of material obtained from Medline and PubMed literature searches up to May 2011. The recognition of FICZ as a potent, endogenous ligand of AHR provided a molecular link between light exposure and AHR signaling and function. The uncovering of the bifurcated signaling pathway of AHR in the mammalian UV response - that is, activation of the cytoplasmic AHR by light via FICZ leads to: i) AHR/AH response element-dependent transcription to induce CYP1A1 and ii) activation of the AHR-pp60(src)-EGFR pathway to induce Cox-2 - put forward a working model for the multiple roles of AHR in skin function and disease that include drug metabolism, circadian oscillation, melanogenesis, inflammation, immunosuppression and cancer. Such findings suggest AHR as a therapeutic target for cancer, autoimmune dysfunction, inflammatory disease and stem cell therapy. JF - Expert opinion on drug metabolism & toxicology AU - Ma, Qiang AD - Receptor Biology Laboratory, Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Mailstop 3014, 1095 Willowdale Rd, Morgantown, WV 26505, USA. qam1@cdc.gov Y1 - 2011/10// PY - 2011 DA - October 2011 SP - 1267 EP - 1293 VL - 7 IS - 10 KW - 6-formylindolo(3,2-b)carbazole KW - 0 KW - Carbazoles KW - Ligands KW - NF-kappa B KW - Receptors, Aryl Hydrocarbon KW - Tryptophan KW - 8DUH1N11BX KW - Cytochrome P-450 CYP1A1 KW - EC 1.14.14.1 KW - Index Medicus KW - Animals KW - Ultraviolet Rays KW - Cytochrome P-450 CYP1A1 -- genetics KW - Humans KW - Cytochrome P-450 CYP1A1 -- metabolism KW - Tryptophan -- metabolism KW - Skin -- radiation effects KW - Inactivation, Metabolic KW - Light KW - DNA Damage -- radiation effects KW - Signal Transduction KW - Cytochrome P-450 CYP1A1 -- drug effects KW - Immunosuppression KW - NF-kappa B -- metabolism KW - Carbazoles -- pharmacokinetics KW - Receptors, Aryl Hydrocarbon -- metabolism KW - Receptors, Aryl Hydrocarbon -- genetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/890678166?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Expert+opinion+on+drug+metabolism+%26+toxicology&rft.atitle=Influence+of+light+on+aryl+hydrocarbon+receptor+signaling+and+consequences+in+drug+metabolism%2C+physiology+and+disease.&rft.au=Ma%2C+Qiang&rft.aulast=Ma&rft.aufirst=Qiang&rft.date=2011-10-01&rft.volume=7&rft.issue=10&rft.spage=1267&rft.isbn=&rft.btitle=&rft.title=Expert+opinion+on+drug+metabolism+%26+toxicology&rft.issn=1744-7607&rft_id=info:doi/10.1517%2F17425255.2011.614947 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-01-20 N1 - Date created - 2011-09-16 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1517/17425255.2011.614947 ER - TY - JOUR T1 - Mortality and end-stage renal disease incidence among dry cleaning workers. AN - 889451215; 21172794 AB - Perchloroethylene (PCE) is a known animal carcinogen and probable human carcinogen. Dry cleaning exposures, particularly PCE, are also associated with renal toxicity. The objective was to follow-up a cohort of dry cleaners to evaluate mortality and assess end-stage renal disease (ESRD) morbidity. This study adds 8 years of mortality follow-up for 1704 dry cleaning workers in four cities. Employees eligible for inclusion worked for ≥1 year before 1960 in a shop using PCE as the primary solvent. Life table analyses for mortality and ESRD morbidity were conducted. Only employees alive on 1 January 1977 were included in ESRD analyses. Overall cancer deaths were in significant excess in this cohort (standardised mortality ratio (SMR) 1.22, 95% CI 1.09 to 1.36). Oesophageal, lung and tongue cancers had significant excesses of deaths. Oesophageal cancer risk was highest among those employed in a PCE-using shop for ≥5 years with ≥20 years' latency since first such employment. Deaths from non-malignant underlying diseases of the stomach and duodenum were in significant excess. Hypertensive ESRD morbidity was significantly elevated in the entire cohort (standardised incidence ratio (SIR) 1.98, 95% CI 1.11 to 3.27), and among workers employed only in PCE-using dry cleaning shops for ≥5 years. Employment in the dry cleaning industry and occupational exposure to PCE are associated with an increased risk for ESRD and for cancer at several sites. The employment duration findings for oesophageal cancer and hypertensive ESRD further support an association with PCE exposure instead of lifestyle or socioeconomic factors. JF - Occupational and environmental medicine AU - Calvert, Geoffrey M AU - Ruder, Avima M AU - Petersen, Martin R AD - Division of Surveillance, Hazard Evaluations and Field Studies, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, R-17, Cincinnati, OH 45226, USA. jac6@cdc.gov Y1 - 2011/10// PY - 2011 DA - October 2011 SP - 709 EP - 716 VL - 68 IS - 10 KW - Solvents KW - 0 KW - Tetrachloroethylene KW - TJ904HH8SN KW - Index Medicus KW - Young Adult KW - Stomach Diseases -- chemically induced KW - Humans KW - Head and Neck Neoplasms -- chemically induced KW - Head and Neck Neoplasms -- mortality KW - Duodenal Diseases -- mortality KW - Morbidity KW - Duodenal Diseases -- chemically induced KW - Adult KW - Stomach Diseases -- mortality KW - Incidence KW - Follow-Up Studies KW - United States -- epidemiology KW - Time Factors KW - Laundering KW - Female KW - Male KW - Solvents -- toxicity KW - Occupational Exposure -- adverse effects KW - Tetrachloroethylene -- toxicity KW - Kidney Failure, Chronic -- chemically induced KW - Occupational Diseases -- chemically induced KW - Kidney Failure, Chronic -- epidemiology KW - Occupational Diseases -- mortality UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/889451215?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Occupational+and+environmental+medicine&rft.atitle=Mortality+and+end-stage+renal+disease+incidence+among+dry+cleaning+workers.&rft.au=Calvert%2C+Geoffrey+M%3BRuder%2C+Avima+M%3BPetersen%2C+Martin+R&rft.aulast=Calvert&rft.aufirst=Geoffrey&rft.date=2011-10-01&rft.volume=68&rft.issue=10&rft.spage=709&rft.isbn=&rft.btitle=&rft.title=Occupational+and+environmental+medicine&rft.issn=1470-7926&rft_id=info:doi/10.1136%2Foem.2010.060665 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-11-15 N1 - Date created - 2011-09-13 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1136/oem.2010.060665 ER - TY - JOUR T1 - The evolution of skin notations for occupational risk assessment: a new NIOSH strategy. AN - 888089892; 21689711 AB - This article presents an overview of a strategy for assignment of hazard-specific skin notations (SK), developed by the National Institute for Occupational Safety and Health (NIOSH). This health hazard characterization strategy relies on multiple SKs capable of delineating systemic (SYS), direct (DIR), and immune-mediated (SEN) adverse effects caused by dermal exposures to chemicals. One advantage of the NIOSH strategy is the ability to combine SKs when it is determined that a chemical may cause multiple adverse effects following dermal contact (e.g., SK: SYS-DIR-SEN). Assignment of the SKs is based on a weight-of-evidence (WOE) approach, which refers to the critical examination of all available data from diverse lines of evidence and the derivation of a scientific interpretation based on the collective body of data including its relevance, quality, and reported results. Numeric cutoff values, based on indices of toxic potency, serve as guidelines to aid in consistently determining a chemical's relative toxicity and hazard potential. The NIOSH strategy documents the scientific rationale for determination of the hazard potential of a chemical and the subsequent assignment of SKs. A case study of acrylamide is presented as an application of the NIOSH strategy. Published by Elsevier Inc. JF - Regulatory toxicology and pharmacology : RTP AU - Dotson, G Scott AU - Chen, Chen-Peng AU - Gadagbui, Bernard AU - Maier, Andrew AU - Ahlers, Heinz W AU - Lentz, Thomas J AD - Education and Information Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, OH 45227, USA. fya8@cdc.gov Y1 - 2011/10// PY - 2011 DA - October 2011 SP - 53 EP - 62 VL - 61 IS - 1 KW - Hazardous Substances KW - 0 KW - Index Medicus KW - United States KW - Risk KW - Animals KW - Humans KW - Male KW - Female KW - Occupational Exposure KW - Hazardous Substances -- classification KW - Skin -- drug effects KW - Skin -- metabolism KW - Hazardous Substances -- pharmacokinetics KW - Skin Diseases -- metabolism KW - Skin Diseases -- mortality KW - National Institute for Occupational Safety and Health (U.S.) -- standards KW - Skin Diseases -- pathology KW - Skin Diseases -- chemically induced KW - Risk Assessment -- methods KW - Hazardous Substances -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/888089892?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Regulatory+toxicology+and+pharmacology+%3A+RTP&rft.atitle=The+evolution+of+skin+notations+for+occupational+risk+assessment%3A+a+new+NIOSH+strategy.&rft.au=Dotson%2C+G+Scott%3BChen%2C+Chen-Peng%3BGadagbui%2C+Bernard%3BMaier%2C+Andrew%3BAhlers%2C+Heinz+W%3BLentz%2C+Thomas+J&rft.aulast=Dotson&rft.aufirst=G&rft.date=2011-10-01&rft.volume=61&rft.issue=1&rft.spage=53&rft.isbn=&rft.btitle=&rft.title=Regulatory+toxicology+and+pharmacology+%3A+RTP&rft.issn=1096-0295&rft_id=info:doi/10.1016%2Fj.yrtph.2011.06.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-04-06 N1 - Date created - 2011-09-07 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.yrtph.2011.06.002 ER - TY - JOUR T1 - How effective are severe disciplinary policies? School policies and offending from adolescence into young adulthood AN - 1512194279; 201215900 AB - Based on the stage environment and the person environment fit perspectives, the current study examined the relation between school disciplinary policies and offending from adolescence into young adulthood. Using Waves I and 111 of the National Longitudinal Study of Adolescent Health (a.k.a., Add Health), hierarchical multinomial logistic regression models were utilized to test whether school disciplinary policies were related to offending patterns during adolescence and young adulthood. Descriptive results suggest that, overall, severe school policies were not associated with the course of offending. However, relations between individual characteristics (i.e., inattention and impulsivity) and offending patterns did appear to differ depending on the severity of disciplinary policies. Within schools with more severe policies, adolescents scoring higher on inattention were more likely to be in the adolescent-limited offender group over the persistent offender group. On the other hand, adolescents with high levels of impulsivity were more likely to be in the persistent group over the non-offender group within schools with more severe policies. The results suggest that severe policies may not be effective for all students and the policies, alone, may not be promising avenues for the prevention of offending during adolescence and young adulthood. [Copyright the Society for the Study of School Psychology; published by Elsevier Ltd.] JF - Journal of School Psychology AU - Matjasko, Jennifer L AD - National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, 4770 Buford Highway NE, MS-F64, Atlanta, GA 30341. Tel.: + 1 770 488 4267; fax: + 1 770 488 1360 jmatjasko@cdc.gov Y1 - 2011/10// PY - 2011 DA - October 2011 SP - 555 EP - 572 PB - Elsevier Science, Amsterdam The Netherlands VL - 49 IS - 5 SN - 0022-4405, 0022-4405 KW - School policies, Offending, Adolescence, Inattention, Impulsivity, Young adulthood KW - Attention deficits KW - Young adulthood KW - Health KW - Impulsivity KW - Adolescents KW - Offending KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1512194279?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+School+Psychology&rft.atitle=How+effective+are+severe+disciplinary+policies%3F+School+policies+and+offending+from+adolescence+into+young+adulthood&rft.au=Matjasko%2C+Jennifer+L&rft.aulast=Matjasko&rft.aufirst=Jennifer&rft.date=2011-10-01&rft.volume=49&rft.issue=5&rft.spage=555&rft.isbn=&rft.btitle=&rft.title=Journal+of+School+Psychology&rft.issn=00224405&rft_id=info:doi/ LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2014-04-01 N1 - Last updated - 2016-09-27 N1 - CODEN - JSCPAA N1 - SubjectsTermNotLitGenreText - Adolescents; Offending; Young adulthood; Impulsivity; Health; Attention deficits ER - TY - JOUR T1 - Exploring the Context: Contemporary Public Health AN - 1125283893; 201227014 AB - Discusses a framework for public health action. Part of a special journal issue discussing the subject of integrating public health into medical education. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Monroe, Judith A AD - Office for State, Tribal, Local, and Territorial Support, CDC, 1600 Clifton Road MS E70, Atlanta GA 30329 fsu6@cdc.gov Y1 - 2011/10// PY - 2011 DA - October 2011 SP - S155 EP - S159 PB - Elsevier Science, New York NY VL - 41 IS - 4 SN - 0749-3797, 0749-3797 KW - Medical education KW - Public health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1125283893?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Exploring+the+Context%3A+Contemporary+Public+Health&rft.au=Monroe%2C+Judith+A&rft.aulast=Monroe&rft.aufirst=Judith&rft.date=2011-10-01&rft.volume=41&rft.issue=4&rft.spage=S155&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2011.06.015 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2013-06-01 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Public health; Medical education DO - http://dx.doi.org/10.1016/j.amepre.2011.06.015 ER - TY - JOUR T1 - INVERSE RELATIONSHIP BETWEEN PRODUCTIVITY AND FARM SIZE: THE CASE OF CHINA AN - 1030886047; 2011-226491 AB - In developing agricultures, past research has suggested an inverse relationship between farm productivity and size. The raw data from China show such an inverse relationship. However, the inverse relationship disappears after we instrument for land area using the fact that one of the objectives of the land allocation process in rural China is to ensure local households to meet their nutritional needs. The empirical inverse relationship is likely due to the failure to account for the unobserved land quality that is unevenly distributed across the farm size continuum, rather than inherent to China's agriculture. (JEL O13, Q12, Q15). Adapted from the source document. JF - Contemporary Economic Policy AU - Chen, Zhuo AU - Huffman, Wallace E AU - Rozelle, Scott AD - Chen: Visiting Scholar, Chicago Center of Excellence in Health Promotion Economics, The University of Chicago, 1600 Clifton Rd NE, MS-E33, Atlanta, GA 30333. Phone 404-498-6317, Fax 404-498-1111, zchen1@cdc.gov Y1 - 2011/10// PY - 2011 DA - October 2011 SP - 580 EP - 592 PB - Wiley-Blackwell, Oxford, UK VL - 29 IS - 4 SN - 1074-3529, 1074-3529 KW - Economic conditions and policy - Economic policy, planning, and development KW - Agriculture and agricultural policy - Agricultural economics and farm holdings KW - Environment and environmental policy - Ecology and environmental policy KW - Agriculture and agricultural policy - Crop management and agricultural production KW - Population groups, population policy, and demographics - Demography and census KW - Agriculture KW - Farms KW - Land KW - Households KW - Economic policy KW - China (People's Republic) KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1030886047?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Contemporary+Economic+Policy&rft.atitle=INVERSE+RELATIONSHIP+BETWEEN+PRODUCTIVITY+AND+FARM+SIZE%3A+THE+CASE+OF+CHINA&rft.au=Chen%2C+Zhuo%3BHuffman%2C+Wallace+E%3BRozelle%2C+Scott&rft.aulast=Chen&rft.aufirst=Zhuo&rft.date=2011-10-01&rft.volume=29&rft.issue=4&rft.spage=580&rft.isbn=&rft.btitle=&rft.title=Contemporary+Economic+Policy&rft.issn=10743529&rft_id=info:doi/10.1111%2Fj.1465-7287.2010.00236.x LA - English DB - PAIS Index N1 - Date revised - 2012-08-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Economic policy; China (People's Republic); Farms; Land; Agriculture; Households DO - http://dx.doi.org/10.1111/j.1465-7287.2010.00236.x ER - TY - JOUR T1 - Coal dust exposure and mortality from ischemic heart disease among a cohort of U.S. coal miners AN - 1017960268; 16691512 AB - Background Particulate exposure from air pollution increases the risk of ischemic heart disease (IHD) mortality. Although coal miners are highly exposed to coal dust particulate, studies of IHD mortality risk among coal miners have had inconsistent results. Previous studies may have been biased by the healthy worker effect. Methods We examined the dose-response relationship between cumulative coal dust exposure, coal rank, and IHD mortality among a cohort of underground coal miners who participated in the National Study of Coal Workers' Pneumoconiosis. Results After adjusting for age, smoking, and body mass index, risk of IHD mortality increased at higher levels of coal dust exposure. Mortality risk was also associated with coal rank region. Conclusion There was an increased risk of mortality from IHD associated with cumulative exposure to coal dust, and with coal rank. The effect of coal rank may be due differences in the composition of coal mine dust particulate. The association of risk of IHD mortality with cumulative particulate exposure is consistent with air pollution studies. Am. J. Ind. Med. 54:727-733, 2011. ? 2011 Wiley-Liss, Inc. JF - American Journal of Industrial Medicine AU - Landen, Deborah D AU - Wassell, James T AU - McWilliams, Linda AU - Patel, Ami AD - Office of Mine Safety and Health Research, National Institute for Occupational Safety and Health, Pittsburgh, Pennsylvania, dlanden@cdc.gov Y1 - 2011/10// PY - 2011 DA - Oct 2011 SP - 727 EP - 733 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 54 IS - 10 SN - 1097-0274, 1097-0274 KW - Pollution Abstracts; Toxicology Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - Age KW - Occupational safety KW - Pneumoconiosis KW - Particulates KW - Coal KW - heart diseases KW - Dust KW - Workers KW - Smoking KW - Dose-response effects KW - Occupational exposure KW - Heart diseases KW - Mortality KW - Ischemia KW - Mines KW - Air pollution KW - USA KW - Coal dust KW - Mining KW - Body mass index KW - X 24380:Social Poisons & Drug Abuse KW - P 0000:AIR POLLUTION KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1017960268?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Coal+dust+exposure+and+mortality+from+ischemic+heart+disease+among+a+cohort+of+U.S.+coal+miners&rft.au=Landen%2C+Deborah+D%3BWassell%2C+James+T%3BMcWilliams%2C+Linda%3BPatel%2C+Ami&rft.aulast=Landen&rft.aufirst=Deborah&rft.date=2011-10-01&rft.volume=54&rft.issue=10&rft.spage=727&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=10970274&rft_id=info:doi/10.1002%2Fajim.20986 L2 - http://onlinelibrary.wiley.com/doi/10.1002/ajim.20986/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2013-11-15 N1 - SubjectsTermNotLitGenreText - Mortality; Age; Pneumoconiosis; Coal; Ischemia; Mines; Dust; Air pollution; Smoking; Workers; Dose-response effects; Coal dust; Body mass index; Occupational exposure; Heart diseases; Occupational safety; Mining; Particulates; heart diseases; USA DO - http://dx.doi.org/10.1002/ajim.20986 ER - TY - CPAPER T1 - An Update on Postpartum Group A Streptococcal Infections T2 - 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AN - 1313100269; 6111690 JF - 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AU - Van Beneden, Chris Y1 - 2011/09/17/ PY - 2011 DA - 2011 Sep 17 KW - Infection KW - Postpartum KW - Streptococcus UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313100269?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=51st+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.atitle=An+Update+on+Postpartum+Group+A+Streptococcal+Infections&rft.au=Van+Beneden%2C+Chris&rft.aulast=Van+Beneden&rft.aufirst=Chris&rft.date=2011-09-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=51st+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.issn=&rft_id=info:doi/ L2 - http://www.icaac.org/images/icaac2011_program_web.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Cholera in Haiti: Epidemiology, Microbiology, and Management T2 - 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AN - 1313100189; 6111686 JF - 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AU - Dowell, Scott Y1 - 2011/09/17/ PY - 2011 DA - 2011 Sep 17 KW - Caribbean Sea, Greater Antilles, Haiti KW - Cholera KW - Epidemiology KW - Microbiology KW - Pathogenic bacteria KW - Bacterial diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313100189?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=51st+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.atitle=Cholera+in+Haiti%3A+Epidemiology%2C+Microbiology%2C+and+Management&rft.au=Dowell%2C+Scott&rft.aulast=Dowell&rft.aufirst=Scott&rft.date=2011-09-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=51st+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.issn=&rft_id=info:doi/ L2 - http://www.icaac.org/images/icaac2011_program_web.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Global Measles: Opportunities and Challenges T2 - 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AN - 1313099880; 6111503 JF - 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AU - Seward, Jane Y1 - 2011/09/17/ PY - 2011 DA - 2011 Sep 17 KW - Measles UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313099880?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=51st+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.atitle=Global+Measles%3A+Opportunities+and+Challenges&rft.au=Seward%2C+Jane&rft.aulast=Seward&rft.aufirst=Jane&rft.date=2011-09-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=51st+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.issn=&rft_id=info:doi/ L2 - http://www.icaac.org/images/icaac2011_program_web.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Cryptococcal Antigenemia Among Hospitalized, HIVInfected Patients with Acute Respiratory Infections and without Meningitis in Thailand T2 - 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AN - 1313074002; 6111332 JF - 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AU - Harris, J AU - Lindsley, M AU - Henchaichon, S AU - Poonwan, N AU - Naorat, S AU - Prapasiri, P AU - Chantra, S AU - Chang, L AU - Park, B AU - Baggett, H AU - Chittaganpitch, M AU - Mekha, N AU - Maloney, S AU - Ruamcharoen, F Y1 - 2011/09/17/ PY - 2011 DA - 2011 Sep 17 KW - Thailand KW - Infection KW - Hospitals KW - Antigenemia KW - Meningitis KW - Respiration KW - Metabolism KW - Human immunodeficiency virus KW - Cryptococcus UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313074002?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=51st+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.atitle=Cryptococcal+Antigenemia+Among+Hospitalized%2C+HIVInfected+Patients+with+Acute+Respiratory+Infections+and+without+Meningitis+in+Thailand&rft.au=Harris%2C+J%3BLindsley%2C+M%3BHenchaichon%2C+S%3BPoonwan%2C+N%3BNaorat%2C+S%3BPrapasiri%2C+P%3BChantra%2C+S%3BChang%2C+L%3BPark%2C+B%3BBaggett%2C+H%3BChittaganpitch%2C+M%3BMekha%2C+N%3BMaloney%2C+S%3BRuamcharoen%2C+F&rft.aulast=Harris&rft.aufirst=J&rft.date=2011-09-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=51st+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.issn=&rft_id=info:doi/ L2 - http://www.icaac.org/images/icaac2011_program_web.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Therapeutic Potential of Fluoroquinolones to Treat Poxvirus Infections T2 - 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AN - 1313073305; 6111075 JF - 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AU - Lee, K AU - Karem, K AU - Damon, I Y1 - 2011/09/17/ PY - 2011 DA - 2011 Sep 17 KW - Infection KW - Fluoroquinolones KW - Poxvirus UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313073305?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=51st+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.atitle=Therapeutic+Potential+of+Fluoroquinolones+to+Treat+Poxvirus+Infections&rft.au=Lee%2C+K%3BKarem%2C+K%3BDamon%2C+I&rft.aulast=Lee&rft.aufirst=K&rft.date=2011-09-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=51st+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.issn=&rft_id=info:doi/ L2 - http://www.icaac.org/images/icaac2011_program_web.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Insights from Animal Models T2 - 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AN - 1313065317; 6111604 JF - 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AU - Heneine, Walid Y1 - 2011/09/17/ PY - 2011 DA - 2011 Sep 17 KW - Animal models UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313065317?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=51st+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.atitle=Insights+from+Animal+Models&rft.au=Heneine%2C+Walid&rft.aulast=Heneine&rft.aufirst=Walid&rft.date=2011-09-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=51st+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.issn=&rft_id=info:doi/ L2 - http://www.icaac.org/images/icaac2011_program_web.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - A Large Outbreak of Trichosporonosis Among Intensive Care Unit Patients: Jamaica 2010 T2 - 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AN - 1313061271; 6110491 JF - 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AU - Fanfair, R AU - Heslop, O AU - Etienne, K AU - Rainford, L AU - Roy, M AU - Gade, L AU - Noble-Wang, J AU - O'connell, H AU - Peterson, J AU - Brandt, M AU - Lindo, J AU - Balajee, A AU - Park, B Y1 - 2011/09/17/ PY - 2011 DA - 2011 Sep 17 KW - Caribbean Sea, Greater Antilles, Jamaica KW - Outbreaks KW - Intensive care units KW - trichosporonosis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313061271?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=51st+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.atitle=A+Large+Outbreak+of+Trichosporonosis+Among+Intensive+Care+Unit+Patients%3A+Jamaica+2010&rft.au=Fanfair%2C+R%3BHeslop%2C+O%3BEtienne%2C+K%3BRainford%2C+L%3BRoy%2C+M%3BGade%2C+L%3BNoble-Wang%2C+J%3BO%27connell%2C+H%3BPeterson%2C+J%3BBrandt%2C+M%3BLindo%2C+J%3BBalajee%2C+A%3BPark%2C+B&rft.aulast=Fanfair&rft.aufirst=R&rft.date=2011-09-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=51st+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.issn=&rft_id=info:doi/ L2 - http://www.icaac.org/images/icaac2011_program_web.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Emerging Resistance in Nontyphoidal Salmonella T2 - 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AN - 1313032334; 6110703 JF - 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AU - Karp, Beth Y1 - 2011/09/17/ PY - 2011 DA - 2011 Sep 17 KW - Anadromous species KW - Salmonella UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313032334?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=51st+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.atitle=Emerging+Resistance+in+Nontyphoidal+Salmonella&rft.au=Karp%2C+Beth&rft.aulast=Karp&rft.aufirst=Beth&rft.date=2011-09-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=51st+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.issn=&rft_id=info:doi/ L2 - http://www.icaac.org/images/icaac2011_program_web.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - A Cluster of Necrotizing Cutaneous Mucormycosis Following a Tornado: Joplin, Missouri, 2011 T2 - 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AN - 1313022521; 6112200 JF - 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AU - Neblett Fanfair, R. AU - Bennett, S AU - Benedict, K AU - Bos, J AU - Lo, Y. AU - Adebanjo, T Y1 - 2011/09/17/ PY - 2011 DA - 2011 Sep 17 KW - USA, Missouri KW - Mucormycosis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313022521?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=51st+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.atitle=A+Cluster+of+Necrotizing+Cutaneous+Mucormycosis+Following+a+Tornado%3A+Joplin%2C+Missouri%2C+2011&rft.au=Neblett+Fanfair%2C+R.%3BBennett%2C+S%3BBenedict%2C+K%3BBos%2C+J%3BLo%2C+Y.%3BAdebanjo%2C+T&rft.aulast=Neblett+Fanfair&rft.aufirst=R.&rft.date=2011-09-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=51st+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.issn=&rft_id=info:doi/ L2 - http://www.icaac.org/images/icaac2011_program_web.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Status of C. difficile Vaccine Development and Target Populations T2 - 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AN - 1312985714; 6110765 JF - 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) AU - McDonald, Clifford Y1 - 2011/09/17/ PY - 2011 DA - 2011 Sep 17 KW - vaccines KW - Vaccines KW - Disease control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312985714?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=51st+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.atitle=Status+of+C.+difficile+Vaccine+Development+and+Target+Populations&rft.au=McDonald%2C+Clifford&rft.aulast=McDonald&rft.aufirst=Clifford&rft.date=2011-09-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=51st+Interscience+Conference+on+Antimicrobial+Agents+and+Chemotherapy+%28ICAAC+2012%29&rft.issn=&rft_id=info:doi/ L2 - http://www.icaac.org/images/icaac2011_program_web.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - JOUR T1 - Cerium oxide nanoparticle-induced pulmonary inflammation and alveolar macrophage functional change in rats AN - 926891879; 16401676 AB - The use of cerium compounds as diesel fuel catalyst results in the emission of cerium oxide nanoparticles (CeO sub(2)) in the exhaust. This study characterized the potential effects of CeO sub(2) exposure on lung toxicity. Male Sprague Dawley rats were exposed to CeO sub(2) by a single intratracheal instillation at 0.15, 0.5, 1, 3.5 or 7 mg/kg body weight. At 1 day after exposure, CeO sub(2) significantly reduced NO production, but increased IL-12 production, by alveolar macrophages (AM) in response to ex vivo lipopolysacchride (LPS) challenge, and caused AM apoptosis, through activation of caspases 9 and 3. CeO sub(2) exposure markedly increased suppressor of cytokine signaling-1 at 1-day and elevated arginase-1 at 28-day post exposure in lung cells, while osteopontin was significantly elevated in lung tissue at both time points. CeO sub(2) induced inflammation, cytotoxicity, air/blood barrier damage, and phospholipidosis with enlarged AM. Thus, CeO sub(2) induced lung inflammation and injury in lungs which may lead to fibrosis. JF - Nanotoxicology AU - Ma, J Y AU - Zhao, H AU - Mercer, R R AU - Barger, M AU - Rao, M AU - Meighan, T AU - Schwegler-Berry, D AU - Castranova, V AU - Ma, J K AD - PPRB/HELD, NIOSH, 1095 Willowdale Road, Morgantown, West Virginia 26505-2888, USA, iym1@cdc.gov Y1 - 2011/09// PY - 2011 DA - Sep 2011 SP - 312 EP - 325 VL - 5 IS - 3 SN - 1743-5390, 1743-5390 KW - Immunology Abstracts; Toxicology Abstracts KW - Alveoli KW - Lung KW - X 24370:Natural Toxins KW - F 06910:Microorganisms & Parasites UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/926891879?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Nanotoxicology&rft.atitle=Cerium+oxide+nanoparticle-induced+pulmonary+inflammation+and+alveolar+macrophage+functional+change+in+rats&rft.au=Ma%2C+J+Y%3BZhao%2C+H%3BMercer%2C+R+R%3BBarger%2C+M%3BRao%2C+M%3BMeighan%2C+T%3BSchwegler-Berry%2C+D%3BCastranova%2C+V%3BMa%2C+J+K&rft.aulast=Ma&rft.aufirst=J&rft.date=2011-09-01&rft.volume=5&rft.issue=3&rft.spage=312&rft.isbn=&rft.btitle=&rft.title=Nanotoxicology&rft.issn=17435390&rft_id=info:doi/10.3109%2F17435390.2010.519835 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2014-03-20 N1 - SubjectsTermNotLitGenreText - Lung DO - http://dx.doi.org/10.3109/17435390.2010.519835 ER - TY - JOUR T1 - Effects of Dram Shop Liability and Enhanced Overservice Law Enforcement Initiatives on Excessive Alcohol Consumption and Related Harms: Two Community Guide Systematic Reviews AN - 919970711; 201202811 AB - Context: Dram shop liability holds the owner or server(s) at a bar, restaurant, or other location where a patron, adult or underage, consumed his or her last alcoholic beverage responsible for harms subsequently inflicted by the patron on others. Liability in a state can be established by case law or statute. Overservice laws prohibit the sale of alcoholic beverages to intoxicated patrons drinking in on-premises retail alcohol outlets (i.e., premises where the alcohol is consumed where purchased); enhanced enforcement of these laws is intended to ensure compliance by premises personnel. Both of these interventions are ultimately designed to promote responsible beverage service by reducing sales to intoxicated patrons, underage youth, or both. This review assesses the effectiveness of dram shop liability and the enhanced enforcement of overservice laws for preventing excessive alcohol consumption and related harms. Evidence acquisition: Studies assessing alcohol-related harms in states adopting dram shop laws were evaluated, as were studies assessing alcohol-related harms in regions with enhanced overservice enforcement. Methods previously developed for systematic reviews for the Guide to Community Preventive Services were used. Evidence synthesis: Eleven studies assessed the association of state dram shop liability with various outcomes, including all-cause motor vehicle crash deaths, alcohol-related motor vehicle crash deaths (the most common outcome assessed in the studies reviewed), alcohol consumption, and other alcohol-related harms. There was a median reduction of 6.4% (range of values 3.7% to 11.3% reduction) in alcohol-related motor vehicle fatalities associated with the presence of dram shop liability in jurisdictions where premises are licensed. Other alcohol-related outcomes also showed a reduction. Only two studies assessed the effects of enhanced enforcement initiatives on alcohol-related outcomes; findings were inconsistent, some indicating benefit and others none. Conclusions: According to Community Guide rules of evidence, the number and consistency of findings indicate strong evidence of the effectiveness of dram shop laws in reducing alcohol-related harms. It will be important to assess the possible effects of legal modifications to dram shop proceedings, such as the imposition of statutes of limitation, increased evidentiary requirements, and caps on recoverable amounts. According to Community Guide rules of evidence, evidence is insufficient to determine the effectiveness of enhanced enforcement of overservice laws for preventing excessive alcohol consumption and related harms. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Rammohan, Veda AU - Hahn, Robert A AU - Elder, Randy AU - Brewer, Robert AU - Fielding, Jonathan AU - Naimi, Timothy S AU - Toomey, Traci L AU - Chattopadhyay, Sajal K AU - Zometa, Carlos AD - Community Guide Branch of the Epidemiology and Analysis Program Office, CDC, Atlanta, Georgia Y1 - 2011/09// PY - 2011 DA - September 2011 SP - 334 EP - 343 PB - Elsevier Science, New York NY VL - 41 IS - 3 SN - 0749-3797, 0749-3797 KW - Alcohol consumption KW - Enforcement KW - Patrons KW - Liability KW - Alcohol related KW - Shops KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/919970711?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Effects+of+Dram+Shop+Liability+and+Enhanced+Overservice+Law+Enforcement+Initiatives+on+Excessive+Alcohol+Consumption+and+Related+Harms%3A+Two+Community+Guide+Systematic+Reviews&rft.au=Rammohan%2C+Veda%3BHahn%2C+Robert+A%3BElder%2C+Randy%3BBrewer%2C+Robert%3BFielding%2C+Jonathan%3BNaimi%2C+Timothy+S%3BToomey%2C+Traci+L%3BChattopadhyay%2C+Sajal+K%3BZometa%2C+Carlos&rft.aulast=Rammohan&rft.aufirst=Veda&rft.date=2011-09-01&rft.volume=41&rft.issue=3&rft.spage=334&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2011.06.027 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2012-02-01 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Shops; Alcohol related; Liability; Enforcement; Alcohol consumption; Patrons DO - http://dx.doi.org/10.1016/j.amepre.2011.06.027 ER - TY - JOUR T1 - Adherence to the Advisory Committee on Immunization Practices Recommendation to Prevent Injuries from Postvaccination Syncope: A National Physician Survey AN - 919969733; 201202015 AB - A survey was administered during October 2008-January 2009 to 425 pediatricians (Peds) and 424 family medicine physicians (FPs) from a nationally representative network. Adherence was defined as reporting routinely observing patients for =15 minutes after vaccination. Data analysis was completed in 2009. Results: The overall response rate was 73%. A minority of physicians (37% Peds, 24% FPs) were aware that ACIP strongly encourages observing patients for 15 minutes postvaccination, but most physicians (69% Peds, 84% FPs) thought that their practice easily could adhere to this recommendation. Lack of room space (76% Peds, 65% FPs) was the most frequently reported barrier. Seventeen percent of physicians reported adherence to postvaccination observation. Practice in a hospital, university, or community health center compared with private practice (RR=1.64, 95% CI=1.05, 2.40); awareness of the ACIP syncope recommendation (RR=5.55, 95% CI=3.60, 9.37); and believing that postvaccination syncope can result in serious injuries (RR=1.74, 95% CI=1.06, 4.22) were independently associated with self-reported adherence. Conclusions: Few physicians are aware of recommendations for postvaccination observation for syncope and even fewer adhere to them. Strategies to improve this should be developed and tested. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Huang, Wan-Ting AU - Suh, Christina AU - Campagna, Elizabeth AU - Broder, Karen R AU - Daley, Matthew F AU - Crane, Lori A AU - Stokley, Shannon AU - Kempe, Allison AD - Epidemic Intelligence Service, Division of Applied Sciences, Scientific Education and Professional Development Program Office, CDC, Atlanta, Georgia Y1 - 2011/09// PY - 2011 DA - September 2011 SP - 317 EP - 321 PB - Elsevier Science, New York NY VL - 41 IS - 3 SN - 0749-3797, 0749-3797 KW - Doctors KW - Response rate KW - Adherence KW - Serious injuries KW - Syncope KW - Immunization KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/919969733?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Adherence+to+the+Advisory+Committee+on+Immunization+Practices+Recommendation+to+Prevent+Injuries+from+Postvaccination+Syncope%3A+A+National+Physician+Survey&rft.au=Huang%2C+Wan-Ting%3BSuh%2C+Christina%3BCampagna%2C+Elizabeth%3BBroder%2C+Karen+R%3BDaley%2C+Matthew+F%3BCrane%2C+Lori+A%3BStokley%2C+Shannon%3BKempe%2C+Allison&rft.aulast=Huang&rft.aufirst=Wan-Ting&rft.date=2011-09-01&rft.volume=41&rft.issue=3&rft.spage=317&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2011.04.016 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2012-02-01 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Doctors; Adherence; Syncope; Immunization; Response rate; Serious injuries DO - http://dx.doi.org/10.1016/j.amepre.2011.04.016 ER - TY - JOUR T1 - Use of Sindbis/Eastern Equine Encephalitis Chimeric Viruses in Plaque Reduction Neutralization Tests for Arboviral Disease Diagnostics AN - 911161066; 16063101 AB - Eastern equine encephalitis virus (EEEV) is a highly virulent, mosquito-borne alphavirus that causes severe and often fatal neurological disease in humans and horses in eastern North American, the Caribbean, and Mexico and throughout Central and South America. EEEV infection is diagnosed serologically by anti-EEEV-specific IgM detection, with confirmation by the plaque reduction neutralization test (PRNT), which is highly specific for alphaviruses. Live virus is used in the PRNT procedure, which currently requires biosafety level 3 containment facilities and select agent security in the case of EEEV. These requirements restrict the ability of public health laboratories to conduct PRNTs. Sindbis virus (SINV)/EEEV recombinant constructs have been engineered to express the immunogenic structural proteins from 2 wild-type EEEV strains in an attenuated form. These SINV/EEEVs, which are not classified as select agents, were evaluated as alternative diagnostic reagents in a PRNT using human, equine, and murine sera. The results indicate that the chimeric viruses exhibit specificity comparable to that of wild-type EEEV, with only a slight reduction in sensitivity. Considering their benefits in increased safety and reduced regulatory requirements, these chimeric viruses should be highly useful in diagnostic laboratories throughout the Americas. JF - Clinical and Vaccine Immunology AU - Johnson, B W AU - Kosoy, O AU - Wang, E AU - Delorey, M AU - Russell, B AU - Bowen, R A AU - Weaver, S C AD - Diagnostic and Reference Laboratory, Arboviral Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado, bfj9@cdc.gov Y1 - 2011/09// PY - 2011 DA - September 2011 SP - 1486 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 18 IS - 9 SN - 1556-6811, 1556-6811 KW - ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Virology & AIDS Abstracts; Immunology Abstracts KW - Neurological diseases KW - Eastern equine encephalitis virus KW - Specificity KW - Viruses KW - Disease control KW - Infection KW - Strains KW - Structural proteins KW - Public health KW - Recombinants KW - South America KW - ASW, Caribbean Sea KW - ASW, Mexico KW - Immunogenicity KW - Sindbis virus KW - Eastern equine encephalitis KW - Alphavirus KW - Plaques KW - Vaccines KW - Containment KW - Aquatic insects KW - Immunoglobulin M KW - V 22350:Immunology KW - F 06905:Vaccines KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/911161066?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+and+Vaccine+Immunology&rft.atitle=Use+of+Sindbis%2FEastern+Equine+Encephalitis+Chimeric+Viruses+in+Plaque+Reduction+Neutralization+Tests+for+Arboviral+Disease+Diagnostics&rft.au=Johnson%2C+B+W%3BKosoy%2C+O%3BWang%2C+E%3BDelorey%2C+M%3BRussell%2C+B%3BBowen%2C+R+A%3BWeaver%2C+S+C&rft.aulast=Johnson&rft.aufirst=B&rft.date=2011-09-01&rft.volume=18&rft.issue=9&rft.spage=1486&rft.isbn=&rft.btitle=&rft.title=Clinical+and+Vaccine+Immunology&rft.issn=15566811&rft_id=info:doi/10.1128%2FCVI.05129-11 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-12-01 N1 - Number of references - 19 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Recombinants; Specificity; Viruses; Disease control; Vaccines; Strains; Containment; Aquatic insects; Public health; Neurological diseases; Immunogenicity; Eastern equine encephalitis; Plaques; Infection; Immunoglobulin M; Structural proteins; Eastern equine encephalitis virus; Sindbis virus; Alphavirus; South America; ASW, Caribbean Sea; ASW, Mexico DO - http://dx.doi.org/10.1128/CVI.05129-11 ER - TY - JOUR T1 - Development of Multiplexed Species Specific Polymerase Chain Reaction Assays for Identification of the Culex (Melanoconion) Species (Diptera: Culicidae) of the Southeastern United States Based on rDNA AN - 902376251; 15762910 AB - Adult female mosquitoes within the subgenus Culex (Melanoconion) Theobald (Diptera: Culicidae) are difficult to identify to species using external morphological features. We present two multiplexed polymerase chain reaction assays that quickly and accurately identify specimens from the southeastern United States based on sequence differences in the internal transcribed spacers of the ribosomal DNA gene array. One assay identifies all species that occur only in Florida, whereas the second assay identifies species that may occur in other southeastern states. These assays require small amounts of DNA, such as DNA from two sonicated legs, or an individual specimen. These assays also may be run as multiple singleplex reactions to determine the mosquito species composition of virus-positive mosquito pools. Reaction volumes may be as low as 10 mu l, which reduces assay cost. JF - Journal of Medical Entomology AU - Williams, Martin R AU - Savage, Harry M AD - Centers for Disease Control and Prevention, 3150 Rampart Road, Fort Collins, CO 80521, hms1@cdc.gov Y1 - 2011/09// PY - 2011 DA - Sep 2011 SP - 961 EP - 966 PB - Entomological Society of America, 9301 Annapolis Rd. Lanham MD 20706 United States VL - 48 IS - 5 SN - 0022-2585, 0022-2585 KW - ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Biochemistry Abstracts 2: Nucleic Acids; Entomology Abstracts KW - Culex (Melanoconion) KW - internal transcribed spacer KW - multiplex polymerase chain reaction KW - mosquito identification KW - USA, Florida KW - Nucleotide sequence KW - Culicidae KW - Spacer KW - USA, Southeast KW - Entomology KW - Species Composition KW - Leg KW - Culex KW - Population genetics KW - DNA KW - Polymerase chain reaction KW - Species composition KW - Diptera KW - Aquatic insects KW - Q1 08203:Taxonomy and morphology KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - N 14830:RNA KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/902376251?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Medical+Entomology&rft.atitle=Development+of+Multiplexed+Species+Specific+Polymerase+Chain+Reaction+Assays+for+Identification+of+the+Culex+%28Melanoconion%29+Species+%28Diptera%3A+Culicidae%29+of+the+Southeastern+United+States+Based+on+rDNA&rft.au=Williams%2C+Martin+R%3BSavage%2C+Harry+M&rft.aulast=Williams&rft.aufirst=Martin&rft.date=2011-09-01&rft.volume=48&rft.issue=5&rft.spage=961&rft.isbn=&rft.btitle=&rft.title=Journal+of+Medical+Entomology&rft.issn=00222585&rft_id=info:doi/10.1603%2FME11081 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Number of references - 1 N1 - Last updated - 2014-12-11 N1 - SubjectsTermNotLitGenreText - Population genetics; Nucleotide sequence; DNA; Polymerase chain reaction; Aquatic insects; Species Composition; Entomology; Leg; Species composition; Spacer; Culex; Culicidae; Diptera; USA, Florida; USA, Southeast DO - http://dx.doi.org/10.1603/ME11081 ER - TY - JOUR T1 - Trends in Work-Related Musculoskeletal Disorders A Comparison of Risk Factors for Symptoms Using Quality of Work Life Data From the 2002 and 2006 General Social Survey AN - 899164250; 15775766 AB - Objective: To assess trends in risk factors for work-related musculoskeletal disorders (MSDs). Methods: Results from two similar national surveys (2002 and 2006) examined trends in relationships between individual, psy-chosocial, and physical factors and MSDs. Results: Findings between years were similar, but important differences included a stronger effect of "Work Stress" on "Pain in Arms," and a stronger combined effect of "Hand Movement" and "Work Stress" on "Pain in Arms." Also, two interactions were statistically significant in the 2006 data, but not in the 2002 data, revealing potentially increased risks. These were "Hand Movement" and "Work Stress" on "Back Pain," and "Heavy Lifting" and "Work Stress" on "Pain in Arms." Conclusion: New strategies for preventing both low back and upper extremity MSDs should focus on work stress, heavy lifting, and hand movement, individually and in combination. JF - Journal of Occupational and Environmental Medicine AU - Waters, T R AU - Dick, R B AU - Krieg, E F AD - Division of Applied Research and Technology, NIOSH, Mail-Stop C-24, 4676 Columbia Parkway, Cincinnati, OH 45226, USA, TRW1@cdc.gov Y1 - 2011/09// PY - 2011 DA - Sep 2011 SP - 1013 EP - 1024 VL - 53 IS - 9 SN - 1076-2752, 1076-2752 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Occupational health KW - Risk factors KW - Stress KW - back pain KW - lifting KW - musculoskeletal system KW - pain UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/899164250?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Trends+in+Work-Related+Musculoskeletal+Disorders+A+Comparison+of+Risk+Factors+for+Symptoms+Using+Quality+of+Work+Life+Data+From+the+2002+and+2006+General+Social+Survey&rft.au=Waters%2C+T+R%3BDick%2C+R+B%3BKrieg%2C+E+F&rft.aulast=Waters&rft.aufirst=T&rft.date=2011-09-01&rft.volume=53&rft.issue=9&rft.spage=1013&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e3181fc8493 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Last updated - 2012-09-24 N1 - SubjectsTermNotLitGenreText - Risk factors; pain; Stress; back pain; lifting; musculoskeletal system; Occupational health DO - http://dx.doi.org/10.1097/JOM.0b013e3181fc8493 ER - TY - JOUR T1 - Facemask Use by Children During Infectious Disease Outbreaks AN - 1257779275; 17458535 AB - An overview of available literature on the use of protective facemasks by children for protection from respiratory infectious agents reveals relatively few articles dealing specifically with the topic, despite their use during recent outbreaks (eg, severe acute respiratory syndrome, pandemic influenza). Little is known about the physiological and psychological burdens imposed by these devices and a child's ability to correctly use and tolerate them. This article focuses on the myriad issues associated with protective facemask use by children in the hope of educating public health personnel, healthcare professionals, and families on their limitations and associated risks, and in the hope of fostering much-needed research. JF - Biosecurity and Bioterrorism AU - Roberge, R AD - Technology Research Branch, National Institute for Occupational Safety and Health, 626 Cochrans Mill Road, Pittsburgh, PA 15236, USA, dtn0@cdc.gov Y1 - 2011/09/01/ PY - 2011 DA - 2011 Sep 01 SP - 225 EP - 231 VL - 9 IS - 3 SN - 1538-7135, 1538-7135 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Children KW - Disasters KW - Influenza KW - Medical personnel KW - Outbreaks KW - Psychology KW - Public health KW - bioterrorism KW - severe acute respiratory syndrome KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1257779275?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biosecurity+and+Bioterrorism&rft.atitle=Facemask+Use+by+Children+During+Infectious+Disease+Outbreaks&rft.au=Roberge%2C+R&rft.aulast=Roberge&rft.aufirst=R&rft.date=2011-09-01&rft.volume=9&rft.issue=3&rft.spage=225&rft.isbn=&rft.btitle=&rft.title=Biosecurity+and+Bioterrorism&rft.issn=15387135&rft_id=info:doi/10.1089%2Fbsp.2011.0009 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-12-01 N1 - Last updated - 2013-01-11 N1 - SubjectsTermNotLitGenreText - Influenza; Psychology; severe acute respiratory syndrome; bioterrorism; Disasters; Outbreaks; Children; Medical personnel; Public health DO - http://dx.doi.org/10.1089/bsp.2011.0009 ER - TY - JOUR T1 - Association of Shift Work With Physical Activity Among Police Officers The Buffalo Cardio-Metabolic Occupational Police Stress Study AN - 1020837278; 15775768 AB - Objective: To examine relations of shift work with occupational, sports, and household physical activity (PA) among police officers. Methods: Self-reported PA was assessed among 350 male and female officers (aged 27 to 66). Day, afternoon, or midnight shift was identified from daily payroll records. Results: Shift work was associated with prevalence of hard-intensity (occupational and sport) PA among men, and very hard-intensity sport PA among women, with afternoon workers reporting the highest prevalence. Shift work was independently associated with total hours of hard-intensity PA among men and very hard-intensity PA among women, with afternoon workers reporting the most hours. Conclusion: Results indicated that hard and very hard-intensity PA varied significantly across shifts with afternoon workers being the most active. JF - Journal of Occupational and Environmental Medicine AU - Ma, C C AU - Burchfiel, C M AU - Fekedulegn, D AU - Andrew, ME AU - Charles, LE AU - Gu, J K AU - Mnatsakanova, A AU - Violanti, J M AD - National Institute for Occupational Safety and Health, HELD/BEB, MS L-4050, 1095 Willowdale Rd, Morgantown, WV 26505, USA, iia4@cdc.gov Y1 - 2011/09// PY - 2011 DA - Sep 2011 SP - 1030 EP - 1036 VL - 53 IS - 9 SN - 1076-2752, 1076-2752 KW - Physical Education Index; Health & Safety Science Abstracts KW - shift work KW - Men KW - Women KW - Stress KW - Exercise KW - working conditions KW - Physical stress KW - police KW - Households KW - Objectives KW - physical activity KW - Police KW - Women (sports) KW - H 1000:Occupational Safety and Health KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1020837278?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Association+of+Shift+Work+With+Physical+Activity+Among+Police+Officers+The+Buffalo+Cardio-Metabolic+Occupational+Police+Stress+Study&rft.au=Ma%2C+C+C%3BBurchfiel%2C+C+M%3BFekedulegn%2C+D%3BAndrew%2C+ME%3BCharles%2C+LE%3BGu%2C+J+K%3BMnatsakanova%2C+A%3BViolanti%2C+J+M&rft.aulast=Ma&rft.aufirst=C&rft.date=2011-09-01&rft.volume=53&rft.issue=9&rft.spage=1030&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e31822589f9 LA - English DB - Physical Education Index; ProQuest Environmental Science Collection N1 - Date revised - 2012-06-01 N1 - Last updated - 2013-11-15 N1 - SubjectsTermNotLitGenreText - Physical stress; Men; Objectives; Women; Exercise; Police; Women (sports); shift work; police; Households; Stress; physical activity; working conditions DO - http://dx.doi.org/10.1097/JOM.0b013e31822589f9 ER - TY - JOUR T1 - Chronic disease and health behaviours linked to experiences of non-consensual sex among women and men AN - 1010709473; 201209541 AB - Objectives: Few studies have examined the association between non-consensual sex and health indicators for both women and men. The current study examined this relationship as part of a large public health survey that collected information on a range of health behaviours and health risks. Methods: The Behavioural Risk Factor Surveillance System (BRFSS) is an annual random-digit-dialled telephone survey providing surveillance of health behaviours and health risks among US adults. In 2005, an optional module on sexual violence was available for use at the discretion of each US state/territory. Over 115,000 respondents in 25 states/territories were administered the sexual violence module within the BRFSS. Logistic regression analyses were conducted from January to December 2008. Results: Among both women and men, previous non-consensual sex was associated with health conditions such as high cholesterol, stroke and heart disease, and risk behaviours such as human immunodeficiency virus risk factors, smoking and excessive drinking. Sexually victimized women were more likely to report having had a heart attack or heart disease than non-victims. Conclusions: The experience of non-consensual sex is associated with a number of chronic disease outcomes and risk factors. The development and implementation of effective sexual violence prevention strategies may reduce the risk of chronic conditions among persons who have experienced sexual victimisation. [Copyright Elsevier B.V.] JF - Public Health AU - Smith, S G AU - Breiding, M J AD - Centers for Disease Control and Prevention, Atlanta, GA, USA ssmith4@cdc.gov Y1 - 2011/09// PY - 2011 DA - September 2011 SP - 653 EP - 659 PB - Elsevier Ltd, The Netherlands VL - 125 IS - 9 SN - 0033-3506, 0033-3506 KW - Sexual violence Victimisation BRFSS Health behaviour Chronic disease KW - Chronic sickness KW - Risk factors KW - Sexual violence KW - Territories KW - Heart diseases KW - Health behaviour KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1010709473?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Public+Health&rft.atitle=Chronic+disease+and+health+behaviours+linked+to+experiences+of+non-consensual+sex+among+women+and+men&rft.au=Smith%2C+S+G%3BBreiding%2C+M+J&rft.aulast=Smith&rft.aufirst=S&rft.date=2011-09-01&rft.volume=125&rft.issue=9&rft.spage=653&rft.isbn=&rft.btitle=&rft.title=Public+Health&rft.issn=00333506&rft_id=info:doi/10.1016%2Fj.puhe.2011.06.006 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2012-05-01 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Health behaviour; Sexual violence; Risk factors; Chronic sickness; Heart diseases; Territories DO - http://dx.doi.org/10.1016/j.puhe.2011.06.006 ER - TY - JOUR T1 - Biomarkers of exposure to triclocarban in urine and serum AN - 899167283; 15167448 AB - 3,4,4'-Trichlorocarbanilide (triclocarban, TCC) is widely used as an antimicrobial agent in a variety of consumer and personal care products. TCC is considered a potential endocrine disruptor, but its potential toxic effects in humans are still largely unknown. Because of its widespread uses, the potential for human exposure to TCC is high. In order to identify adequate exposure biomarkers of TCC, we investigated the metabolic profile of TCC in adult female Sprague Dawley rats after administering TCC once (500mg/kg body weight) by oral gavage. Urine was collected 0-24h before dosing, and 0-24h and 24-48h after dosing. Serum was collected at necropsy 48h after dosing. We identified several metabolites of TCC in urine and serum by on-line solid phase extraction-high performance liquid chromatography-mass spectrometry. We unambiguously identified two major oxidative metabolites of TCC, 3'-hydroxy-TCC and 2'-hydroxy-TCC, by comparing their chromatographic behavior and mass spectral fragmentation patterns with those of authentic standards. By contrast, compared to these oxidative metabolites, we detected very low levels of TCC in the urine or serum. Taken together these data suggest that in rats, oxidation of TCC is a major metabolic pathway. We also measured TCC and its oxidative metabolites in 50 urine and 16 serum samples collected from adults in the United States. The results suggest differences in the metabolic profile of TCC in rats and in humans; oxidation appears to be a minor metabolic pathway in humans. Total (free plus conjugated) TCC could serve as a potential biomarker for human exposure to TCC. JF - Toxicology AU - Ye, Xiaoyun AU - Zhou, Xiaoliu AU - Furr, Johnathan AU - Ahn, Ki Chang AU - Hammock, Bruce D AU - Gray, Earl L AU - Calafat, Antonia M AD - Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA, xay5@cdc.gov Y1 - 2011/08/15/ PY - 2011 DA - 2011 Aug 15 SP - 69 EP - 74 PB - Elsevier B.V., P.O. Box 85 Limerick Ireland VL - 286 IS - 1-3 SN - 0300-483X, 0300-483X KW - Toxicology Abstracts KW - Autopsy KW - Data processing KW - Endocrine disruptors KW - Metabolites KW - biomarkers KW - Antimicrobial agents KW - Spectrometry KW - Body weight KW - Urine KW - Oxidation KW - Metabolic pathways KW - Consumers KW - triclocarban KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/899167283?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology&rft.atitle=Biomarkers+of+exposure+to+triclocarban+in+urine+and+serum&rft.au=Ye%2C+Xiaoyun%3BZhou%2C+Xiaoliu%3BFurr%2C+Johnathan%3BAhn%2C+Ki+Chang%3BHammock%2C+Bruce+D%3BGray%2C+Earl+L%3BCalafat%2C+Antonia+M&rft.aulast=Ye&rft.aufirst=Xiaoyun&rft.date=2011-08-15&rft.volume=286&rft.issue=1-3&rft.spage=69&rft.isbn=&rft.btitle=&rft.title=Toxicology&rft.issn=0300483X&rft_id=info:doi/10.1016%2Fj.tox.2011.05.008 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Autopsy; Data processing; Endocrine disruptors; Metabolites; biomarkers; Spectrometry; Antimicrobial agents; Body weight; Urine; Oxidation; Metabolic pathways; Consumers; triclocarban DO - http://dx.doi.org/10.1016/j.tox.2011.05.008 ER - TY - JOUR T1 - Missed opportunities to prevent tuberculosis in foreign-born persons, Connecticut, 2005-2008 AN - 904497677; 15631163 AB - SETTING: Factors that influence testing for latent tuberculosis infection (LTBI) among foreign-born persons in Connecticut are not well understood. OBJECTIVE: To identify predictors for LTBI testing and challenges related to accessing health care among the foreign-born population in Connecticut. DESIGN: Foreign-born Connecticut residents with confirmed or suspected tuberculosis (TB) disease during June 2005-December 2008 were interviewed regarding health care access and immigration status. Predictors for self-reported testing for LTBI after US entry were determined. RESULTS: Of 161 foreign-born persons interviewed, 48% experienced TB disease within 5 years after arrival. One third (51/156) reported having undergone post-arrival testing for LTBI. Although those with established health care providers were more likely to have reported testing (aOR 4.49, 95%CI 1.48-13.62), only 43% of such persons were tested. Undocumented persons, the majority of whom lacked a provider (53%), were less likely than documented persons to have reported testing (aOR 0.20, 95%CI 0.06-0.67). Hispanic permanent residents (immigrants and refugees) and visitors (persons admitted temporarily) were more likely than non-Hispanics in the respective groups to have reported testing (OR 5.25, 95%CI 1.51-18.31 and OR 7.08, 95%CI 1.30-38.44, respectively). CONCLUSIONS: The self-reported rate of testing for LTBI among foreign-born persons in Connecticut with confirmed or suspected TB was low and differed significantly by ethnicity and immigration status. Strategies are needed to improve health care access for foreign-born persons and expand testing for LTBI, especially among non-Hispanic and undocumented populations. JF - International Journal of Tuberculosis and Lung Disease AU - Guh, A AU - Sosa, L AU - Hadler, J L AU - Lobato, M N AD - Centers for Disease Control and Prevention, 1600 Clifton Rd NE, MS A-31, Atlanta, GA 30329, USA, ggt4@cdc.gov Y1 - 2011/08// PY - 2011 DA - Aug 2011 SP - 1044 EP - 1049 PB - International Union Against Tuberculosis and Lung Disease VL - 15 IS - 8 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology KW - Immigration KW - Mycobacterium KW - Lung diseases KW - Immigrants KW - Tuberculosis KW - Infection KW - Ethnic groups KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/904497677?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Missed+opportunities+to+prevent+tuberculosis+in+foreign-born+persons%2C+Connecticut%2C+2005-2008&rft.au=Guh%2C+A%3BSosa%2C+L%3BHadler%2C+J+L%3BLobato%2C+M+N&rft.aulast=Guh&rft.aufirst=A&rft.date=2011-08-01&rft.volume=15&rft.issue=8&rft.spage=1044&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/10.5588%2Fijtld.10.0518 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Immigration; Immigrants; Lung diseases; Tuberculosis; Infection; Ethnic groups; Mycobacterium DO - http://dx.doi.org/10.5588/ijtld.10.0518 ER - TY - JOUR T1 - Sleep Duration and Biomarkers of Metabolic Function Among Police Officers AN - 893269009; 15630947 AB - Objective: To investigate associations between sleep duration and biomarkers of metabolic function among police officers. Methods: Metabolic markers were measured using standardized methods and sleep duration was assessed from questionnaire data. Mean levels of leptin and adiponectin were assessed across five levels of sleep duration using ANCOVA and linear regression models. Results: Police officers (n = 443) who reported an average of less than 5 hours and at least 8 hours of sleep had higher levels of leptin compared to those who reported an average of 5 to 7 hours of sleep. These associations were stronger and statistically significant among women, officers with BMI of 24.9 kg/m super(2) or less and smaller abdominal height (< 20 cm), and officers who primarily worked on the day shift. Conclusion: Short and long sleep duration were associated with higher leptin levels and may have implications for obesity-related conditions. JF - Journal of Occupational and Environmental Medicine AU - Charles, LE AU - Gu, J K AU - Andrew, ME AU - Violanti, J M AU - Fekedulegn, D AU - Burchfiel, C M AD - National Institute for Occupational Safety and Health, HELD/BEB, MS L-4050, 1095 Willowdale, Rd, Morgantown, WV 26505, USA, lcharles@cdc.gov Y1 - 2011/08// PY - 2011 DA - Aug 2011 SP - 831 EP - 837 VL - 53 IS - 8 SN - 1076-2752, 1076-2752 KW - Health & Safety Science Abstracts KW - Bioindicators KW - police KW - body mass KW - Standards KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/893269009?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Sleep+Duration+and+Biomarkers+of+Metabolic+Function+Among+Police+Officers&rft.au=Charles%2C+LE%3BGu%2C+J+K%3BAndrew%2C+ME%3BViolanti%2C+J+M%3BFekedulegn%2C+D%3BBurchfiel%2C+C+M&rft.aulast=Charles&rft.aufirst=LE&rft.date=2011-08-01&rft.volume=53&rft.issue=8&rft.spage=831&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e31821f5ece LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-09-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Bioindicators; police; body mass; Standards DO - http://dx.doi.org/10.1097/JOM.0b013e31821f5ece ER - TY - JOUR T1 - USE OF EPIDEMIOLOGICAL DATA AND DIRECT BIOASSAY FOR PRIORITIZATION OF AFFECTED POPULATIONS IN A LARGE-SCALE RADIATION EMERGENCY AN - 888113194; 15498058 AB - Following a radiation emergency, evacuated, sheltered or other members of the public would require monitoring for external and/or internal contamination and, if indicated, decontamination. In addition, the potentially-impacted population would be identified for biodosimetry/bioassay or needed medical treatment (chelation therapy, cytokine treatment, etc.) and prioritized for follow-up. Expeditious implementation of these activities presents many challenges, especially when a large population is affected. Furthermore, experience from previous radiation incidents has demonstrated that the number of people seeking monitoring for radioactive contamination (both external and internal) could be much higher than the actual number of contaminated individuals. In the United States, the Department of Health and Human Services is the lead agency to coordinate federal support for population monitoring activities. Population monitoring includes (1) monitoring people for external contamination; (2) monitoring people for internal contamination; (3) population decontamination; (4) collecting epidemiologic data regarding potentially exposed and/or contaminated individuals to prioritize the affected population for limited medical resources; (5) administering available pharmaceuticals for internal decontamination as deemed necessary by appropriate health officials; (6) performing dose reconstruction; and (7) establishing a registry to conduct long-term monitoring of this population for potential long-term health effects. This paper will focus on screening for internal contamination and will describe the use of early epidemiologic data as well as direct bioassay techniques to rapidly identify and prioritize the affected population for further analysis and medical attention. JF - Health Physics AU - Miller, C W AU - Ansari, A AU - Martin, C AU - Chang, A AU - Buzzell, J AU - Whitcomb, RC Jr AD - Radiation Studies Branch, Division of Environmental Hazards and Health Effects, National Center for Environmental Health, Centers for Disease Control and Prevention, MS F-58, 4770 Buford Highway, Atlanta, GA 30341, USA, CMiller1@cdc.gov Y1 - 2011/08// PY - 2011 DA - Aug 2011 SP - 209 EP - 215 PB - Williams & Wilkins, 351 W. Camden St. Baltimore MD 21201 United States VL - 101 IS - 2 SN - 0017-9078, 0017-9078 KW - Toxicology Abstracts; Pollution Abstracts KW - alpha Radiation KW - Data processing KW - Contamination KW - Chelation KW - Radioactive pollution KW - Decontamination KW - USA KW - Bioassays KW - Radiation KW - Cytokines KW - Pharmaceuticals KW - Medical treatment KW - X 24390:Radioactive Materials KW - P 8000:RADIATION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/888113194?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+Physics&rft.atitle=USE+OF+EPIDEMIOLOGICAL+DATA+AND+DIRECT+BIOASSAY+FOR+PRIORITIZATION+OF+AFFECTED+POPULATIONS+IN+A+LARGE-SCALE+RADIATION+EMERGENCY&rft.au=Miller%2C+C+W%3BAnsari%2C+A%3BMartin%2C+C%3BChang%2C+A%3BBuzzell%2C+J%3BWhitcomb%2C+RC+Jr&rft.aulast=Miller&rft.aufirst=C&rft.date=2011-08-01&rft.volume=101&rft.issue=2&rft.spage=209&rft.isbn=&rft.btitle=&rft.title=Health+Physics&rft.issn=00179078&rft_id=info:doi/10.1097%2FHP.0b013e31821dd9a2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-09-01 N1 - Last updated - 2013-08-12 N1 - SubjectsTermNotLitGenreText - alpha Radiation; Data processing; Radiation; Contamination; Chelation; Pharmaceuticals; Cytokines; Decontamination; Bioassays; Radioactive pollution; Medical treatment; USA DO - http://dx.doi.org/10.1097/HP.0b013e31821dd9a2 ER - TY - JOUR T1 - Racial and Ethnic Disparities in Hospitalizations and Deaths Associated with 2009 Pandemic Influenza A (H1N1) Virus Infections in the United States AN - 883030823; 15330848 AB - Using data from the Centers for Disease Control and Prevention's Behavioral Risk Factor Surveillance System, Emerging Infections Program Influenza-Associated Hospitalization Surveillance, and Influenza-Associated Pediatric Mortality Surveillance, we calculated race-ethnicity-specific, age-adjusted rates of self-reported influenza-like illness (ILI) and pH1N1-associated hospitalizations. We used [chi] super(2 tests to evaluate racial-ethnic disparities in ILI-associated health care-seeking behavior and pH1N1 hospitalization. To evaluate pediatric deaths, we compared racial-ethnic proportions of deaths against U.S. population distributions. Results: Prevalence of self-reported ILI was lower among Hispanics (6.5%), higher among American Indians/Alaska Natives (16.2%), and similar among non-Hispanic blacks (7.7%) compared with non-Hispanic whites (8.5%). No racial-ethnic differences were identified in ILI-associated health care-seeking behavior. Age-adjusted pH1N1-associated Emerging Infections Program hospitalization rates were higher among all minority populations (range: 8.1-10.9/100,000 population) compared with non-Hispanic whites (3.0/100,000). The proportion of pH1N1-associated pediatric deaths was higher than expected among Hispanics (31%) and lower than expected among non-Hispanic whites (45%) given the proportions of the U.S. population they comprise (22% and 58%, respectively). Conclusions: Racial-ethnic disparities in pH1N1-associated hospitalizations and pediatric deaths were identified. Vaccination remains the primary intervention for preventing influenza.) JF - Annals of Epidemiology AU - Dee, Deborah L AU - Bensyl, Diana M AU - Gindler, Jacqueline AU - Truman, Benedict I AU - Allen, Barbara G AU - D'Mello, Tiffany AU - Perez, Alejandro AU - Kamimoto, Laurie AU - Biggerstaff, Matthew AU - Blanton, Lenee AU - Fowlkes, Ashley AU - Glover, Maleeka J AU - Swerdlow, David L AU - Finelli, Lyn AD - Division of Reproductive Health, Centers for Disease Control and Prevention, ddee@cdc.gov ddee@cdc.gov ddee@cdc.gov ddee@cdc.gov ddee@cdc.gov Y1 - 2011/08// PY - 2011 DA - Aug 2011 SP - 623 EP - 630 PB - Elsevier B.V., Box 882 New York NY 10159 United States VL - 21 IS - 8 SN - 1047-2797, 1047-2797 KW - Virology & AIDS Abstracts; Risk Abstracts KW - Disease control KW - population distribution KW - disease control KW - Infection KW - influenza KW - pandemics KW - intervention KW - Risk factors KW - infection KW - prevention KW - Ethnic groups KW - USA, Alaska KW - Mortality KW - Data processing KW - Pediatrics KW - Vaccination KW - R2 23060:Medical and environmental health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/883030823?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annals+of+Epidemiology&rft.atitle=Racial+and+Ethnic+Disparities+in+Hospitalizations+and+Deaths+Associated+with+2009+Pandemic+Influenza+A+%28H1N1%29+Virus+Infections+in+the+United+States&rft.au=Dee%2C+Deborah+L%3BBensyl%2C+Diana+M%3BGindler%2C+Jacqueline%3BTruman%2C+Benedict+I%3BAllen%2C+Barbara+G%3BD%27Mello%2C+Tiffany%3BPerez%2C+Alejandro%3BKamimoto%2C+Laurie%3BBiggerstaff%2C+Matthew%3BBlanton%2C+Lenee%3BFowlkes%2C+Ashley%3BGlover%2C+Maleeka+J%3BSwerdlow%2C+David+L%3BFinelli%2C+Lyn&rft.aulast=Dee&rft.aufirst=Deborah&rft.date=2011-08-01&rft.volume=21&rft.issue=8&rft.spage=623&rft.isbn=&rft.btitle=&rft.title=Annals+of+Epidemiology&rft.issn=10472797&rft_id=info:doi/10.1016%2Fj.annepidem.2011.03.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-08-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Mortality; pandemics; Data processing; Pediatrics; Risk factors; Disease control; Infection; Vaccination; intervention; prevention; infection; population distribution; disease control; Ethnic groups; influenza; USA, Alaska DO - http://dx.doi.org/10.1016/j.annepidem.2011.03.002 ER - TY - JOUR T1 - Economic value of home-based, multi-trigger, multicomponent interventions with an environmental focus for reducing asthma morbidity a community guide systematic review. AN - 879484312; 21767734 AB - A recent systematic review of home-based, multi-trigger, multicomponent interventions with an environmental focus showed their effectiveness in reducing asthma morbidity among children and adolescents. These interventions included home visits by trained personnel to assess the level of and reduce adverse effects of indoor environmental pollutants, and educate households with an asthma client to reduce exposure to asthma triggers. The purpose of the present review is to identify economic values of these interventions and present ranges for the main economic outcomes (e.g., program costs, benefit-cost ratios, and incremental cost-effectiveness ratios). Using methods previously developed for Guide to Community Preventive Services economic reviews, a systematic review was conducted to evaluate the economic efficiency of home-based, multi-trigger, multicomponent interventions with an environmental focus to improve asthma-related morbidity outcomes. A total of 1551 studies were identified in the search period (1950 to June 2008), and 13 studies were included in this review. Program costs are reported for all included studies; cost-benefit results for three; and cost-effectiveness results for another three. Information on program cost was provided with varying degrees of completeness: six of the studies did not provide a list of components included in their program cost description (limited cost information), three studies provided a list of program cost components but not a cost per component (partial cost information), and four studies provided both a list of program cost components and costs per component (satisfactory cost information). Program costs per participant per year ranged from $231-$14,858 (in 2007 U.S.$). The major factors affecting program cost, in addition to completeness, were the level of intensity of environmental remediation (minor, moderate, or major), type of educational component (environmental education or self-management), the professional status of the home visitor, and the frequency of visits by the home visitor. Benefit-cost ratios ranged from 5.3-14.0, implying that for every dollar spent on the intervention, the monetary value of the resulting benefits, such as averted medical costs or averted productivity losses, was $5.30-$14.00 (in 2007 U.S.$). The range in incremental cost-effectiveness ratios was $12-$57 (in 2007 U.S.$) per asthma symptom-free day, which means that these interventions achieved each additional symptom-free day for net costs varying from $12-$57. The benefits from home-based, multi-trigger, multicomponent interventions with an environmental focus can match or even exceed their program costs. Based on cost-benefit and cost-effectiveness studies, the results of this review show that these programs provide a good value for dollars spent on the interventions. Published by Elsevier Inc. JF - American journal of preventive medicine AU - Nurmagambetov, Tursynbek A AU - Barnett, Sarah Beth L AU - Jacob, Verughese AU - Chattopadhyay, Sajal K AU - Hopkins, David P AU - Crocker, Deidre D AU - Dumitru, Gema G AU - Kinyota, Stella AU - Task Force on Community Preventive Services AD - Air Pollution and Respiratory Health Branch, Division of Health Hazards and Health Effects, National Center for Environmental Health, CDC, Atlanta, Georgia 30341, USA. ten7@cdc.gov ; Task Force on Community Preventive Services Y1 - 2011/08// PY - 2011 DA - August 2011 SP - S33 EP - S47 VL - 41 IS - 2 Suppl 1 KW - Index Medicus KW - House Calls KW - Environmental Restoration and Remediation -- methods KW - Housing KW - Humans KW - Cost-Benefit Analysis KW - Child KW - Adolescent KW - Environmental Restoration and Remediation -- economics KW - Asthma -- epidemiology KW - Home Care Services -- economics KW - Asthma -- etiology KW - Asthma -- prevention & control KW - Home Care Services -- organization & administration KW - Environmental Exposure -- prevention & control KW - Environmental Exposure -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/879484312?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+journal+of+preventive+medicine&rft.atitle=Economic+value+of+home-based%2C+multi-trigger%2C+multicomponent+interventions+with+an+environmental+focus+for+reducing+asthma+morbidity+a+community+guide+systematic+review.&rft.au=Nurmagambetov%2C+Tursynbek+A%3BBarnett%2C+Sarah+Beth+L%3BJacob%2C+Verughese%3BChattopadhyay%2C+Sajal+K%3BHopkins%2C+David+P%3BCrocker%2C+Deidre+D%3BDumitru%2C+Gema+G%3BKinyota%2C+Stella%3BTask+Force+on+Community+Preventive+Services&rft.aulast=Nurmagambetov&rft.aufirst=Tursynbek&rft.date=2011-08-01&rft.volume=41&rft.issue=2+Suppl+1&rft.spage=S33&rft.isbn=&rft.btitle=&rft.title=American+journal+of+preventive+medicine&rft.issn=1873-2607&rft_id=info:doi/10.1016%2Fj.amepre.2011.05.011 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-11-21 N1 - Date created - 2011-07-19 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Comment In: Am J Prev Med. 2011 Aug;41(2 Suppl 1):S59-61 [21767740] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.amepre.2011.05.011 ER - TY - JOUR T1 - Recommendations from the Task Force on Community Preventive Services to Decrease Asthma Morbidity Through Home-Based, Multi-Trigger, Multicomponent Interventions AN - 1221435624; 201229537 AB - Discusses the Healthy People 2020 goals and objectives, recommendations from other advisory groups, intervention recommendations, and issues concerning children and adolescents versus adults, economic efficiency, and using the recommendations. Part of a special journal issue devoted to the issue of reducing asthma morbidity through home-based environmental interventions. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Task Force on Community Preventive Services AD - Task Force on Community Preventive Services ggd7@cdc.gov Y1 - 2011/08// PY - 2011 DA - August 2011 SP - S1 EP - S4 PB - Elsevier Science, New York NY VL - 41 IS - 2 SN - 0749-3797, 0749-3797 KW - Home based KW - Advisory groups KW - Interventions KW - Asthma KW - Task forces KW - Morbidity KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1221435624?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Recommendations+from+the+Task+Force+on+Community+Preventive+Services+to+Decrease+Asthma+Morbidity+Through+Home-Based%2C+Multi-Trigger%2C+Multicomponent+Interventions&rft.au=Task+Force+on+Community+Preventive+Services&rft.aulast=Task+Force+on+Community+Preventive+Services&rft.aufirst=&rft.date=2011-08-01&rft.volume=41&rft.issue=2&rft.spage=S1&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/ LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2012-12-01 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Interventions; Morbidity; Home based; Asthma; Task forces; Advisory groups ER - TY - JOUR T1 - Infrared imaging for leak detection of N95 filtering facepiece respirators: A pilot study AN - 1017962632; 16691535 AB - Background This study was undertaken to determine the utility of an infrared camera (IRC) for assessing leaks around filtering facepiece respirators (FFR) during quantitative respirator fit testing. Methods Eight subjects underwent quantitative fit testing on six N95 FFR models (48 total fit tests) while simultaneously being recorded with an IRC. Results The IRC detected 49 exhalation leaks during 39 tests and no leaks in nine tests. Exhalation leaks were identified in all failed fit tests (13) and a majority (26 of 35) of passed tests. Anatomically, the nasal region and malar (cheekbone) regions accounted for 71% of identified leak sites. Fit factors for fit tests without identified exhalation leaks were significantly higher than fit tests with leaks detected by IRC (P=0.01). Conclusions Thermal imaging using IRC can detect leaks in respiratory protective equipment and has the potential as a screening tool for assessment of the adequacy of post-donning FFR fit. Am. J. Ind. Med. 54:628-636, 2011. ? 2011 Wiley-Liss, Inc. JF - American Journal of Industrial Medicine AU - Roberge, Raymond J AU - Monaghan, William D AU - Palmiero, Andrew J AU - Shaffer, Ronald AU - Bergman, Michael S AD - National Personal Protective Technology Laboratory/National Institute for Occupational Safety and Health/Centers for Disease Control and Prevention, Pittsburgh, Pennsylvania, dtn0@cdc.gov Y1 - 2011/08// PY - 2011 DA - Aug 2011 SP - 628 EP - 636 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 54 IS - 8 SN - 1097-0274, 1097-0274 KW - Health & Safety Science Abstracts KW - Leak detection KW - infrared imaging KW - Respirators KW - Protective equipment KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1017962632?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Infrared+imaging+for+leak+detection+of+N95+filtering+facepiece+respirators%3A+A+pilot+study&rft.au=Roberge%2C+Raymond+J%3BMonaghan%2C+William+D%3BPalmiero%2C+Andrew+J%3BShaffer%2C+Ronald%3BBergman%2C+Michael+S&rft.aulast=Roberge&rft.aufirst=Raymond&rft.date=2011-08-01&rft.volume=54&rft.issue=8&rft.spage=628&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=10970274&rft_id=info:doi/10.1002%2Fajim.20970 L2 - http://onlinelibrary.wiley.com/doi/10.1002/ajim.20970/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2013-06-28 N1 - SubjectsTermNotLitGenreText - Leak detection; infrared imaging; Respirators; Protective equipment DO - http://dx.doi.org/10.1002/ajim.20970 ER - TY - JOUR T1 - SAR/QSAR methods in public health practice AN - 883030962; 15331531 AB - Methods of (Quantitative) Structure-Activity Relationship ((Q)SAR) modeling play an important and active role in ATSDR programs in support of the Agency mission to protect human populations from exposure to environmental contaminants. They are used for cross-chemical extrapolation to complement the traditional toxicological approach when chemical-specific information is unavailable. SAR and QSAR methods are used to investigate adverse health effects and exposure levels, bioavailability, and pharmacokinetic properties of hazardous chemical compounds. They are applied as a part of an integrated systematic approach in the development of Health Guidance Values (HGVs), such as ATSDR Minimal Risk Levels, which are used to protect populations exposed to toxic chemicals at hazardous waste sites. (Q)SAR analyses are incorporated into ATSDR documents (such as the toxicological profiles and chemical-specific health consultations) to support environmental health assessments, prioritization of environmental chemical hazards, and to improve study design, when filling the priority data needs (PDNs) as mandated by Congress, in instances when experimental information is insufficient. These cases are illustrated by several examples, which explain how ATSDR applies (Q)SAR methods in public health practice. JF - Toxicology and Applied Pharmacology AU - Demchuk, Eugene AU - Ruiz, Patricia AU - Chou, Selene AU - Fowler, Bruce A AD - Agency for Toxic Substances and Disease Registry (ATSDR), Division of Toxicology and Environmental Medicine, Atlanta, GA 30333, USA, edemchuk@cdc.gov Y1 - 2011/07/15/ PY - 2011 DA - 2011 Jul 15 SP - 192 EP - 197 PB - Elsevier B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 254 IS - 2 SN - 0041-008X, 0041-008X KW - Health & Safety Science Abstracts; Environment Abstracts; Toxicology Abstracts KW - structure-activity relationships KW - Data processing KW - Congress KW - Environmental health KW - Pharmacokinetics KW - Public health KW - Bioavailability KW - Waste disposal sites KW - human populations KW - Contaminants KW - Structure-activity relationships KW - Hazardous wastes KW - H 3000:Environment and Ecology KW - X 24310:Pharmaceuticals KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/883030962?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+Applied+Pharmacology&rft.atitle=SAR%2FQSAR+methods+in+public+health+practice&rft.au=Demchuk%2C+Eugene%3BRuiz%2C+Patricia%3BChou%2C+Selene%3BFowler%2C+Bruce+A&rft.aulast=Demchuk&rft.aufirst=Eugene&rft.date=2011-07-15&rft.volume=254&rft.issue=2&rft.spage=192&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+Applied+Pharmacology&rft.issn=0041008X&rft_id=info:doi/10.1016%2Fj.taap.2010.10.017 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-08-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Bioavailability; Data processing; Waste disposal sites; Contaminants; Structure-activity relationships; Pharmacokinetics; Public health; structure-activity relationships; Congress; Environmental health; human populations; Hazardous wastes DO - http://dx.doi.org/10.1016/j.taap.2010.10.017 ER - TY - JOUR T1 - When the facts are just not enough: Credibly communicating about risk is riskier when emotions run high and time is short AN - 883020497; 15331529 AB - When discussing risk with people, commonly subject matter experts believe that conveying the facts will be enough to allow people to assess a risk and respond rationally to that risk. Because of this expectation, experts often become exasperated by the seemingly illogical way people assess personal risk and choose to manage that risk. In crisis situations when the risk information is less defined and choices must be made within impossible time constraints, the thought processes may be even more susceptible to faulty heuristics. Understanding the perception of risk is essential to understanding why the public becomes more or less upset by events. This article explores the psychological underpinnings of risk assessment within emotionally laden events and the risk communication practices that may facilitate subject matter experts to provide the facts in a manner so they can be more certain those facts are being heard. Source credibility is foundational to risk communication practices. The public meeting is one example in which these best practices can be exercised. Risks are risky because risk perceptions differ and the psychosocial environment in which risk is discussed complicates making risk decisions. Experts who want to influence the actions of the public related to a threat or risk should understand that decisions often involve emotional as well as logical components. The media and other social entities will also influence the risk context. The Center for Disease Control and Prevention's crisis and emergency-risk communication (CERC) principles are intended to increase credibility and recognize emotional components of an event. During a risk event, CERC works to calm emotions and increase trust which can help people apply the expertise being offered by response officials. JF - Toxicology and Applied Pharmacology AU - Reynolds, Barbara J AD - U. S. Centers for Disease Control and Prevention, 1600 Clifton Road, N.E, Atlanta, Georgia 30333, Bsr0@cdc.gov Y1 - 2011/07/15/ PY - 2011 DA - 2011 Jul 15 SP - 206 EP - 214 PB - Elsevier B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 254 IS - 2 SN - 0041-008X, 0041-008X KW - Risk Abstracts; Environment Abstracts; Toxicology Abstracts KW - Risk assessment KW - Emotions KW - Psychology KW - Communication KW - Disease control KW - disease control KW - Decision making KW - Communications KW - best practices KW - Perception KW - crises KW - prevention KW - Problem solving KW - X 24310:Pharmaceuticals KW - R2 23110:Psychological aspects KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/883020497?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+Applied+Pharmacology&rft.atitle=When+the+facts+are+just+not+enough%3A+Credibly+communicating+about+risk+is+riskier+when+emotions+run+high+and+time+is+short&rft.au=Reynolds%2C+Barbara+J&rft.aulast=Reynolds&rft.aufirst=Barbara&rft.date=2011-07-15&rft.volume=254&rft.issue=2&rft.spage=206&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+Applied+Pharmacology&rft.issn=0041008X&rft_id=info:doi/10.1016%2Fj.taap.2010.10.023 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-08-01 N1 - Last updated - 2012-04-06 N1 - SubjectsTermNotLitGenreText - Risk assessment; Decision making; Emotions; Perception; Disease control; Communication; Problem solving; best practices; Communications; Psychology; crises; prevention; disease control DO - http://dx.doi.org/10.1016/j.taap.2010.10.023 ER - TY - JOUR T1 - When the facts are just not enough: credibly communicating about risk is riskier when emotions run high and time is short. AN - 876185889; 21034761 AB - When discussing risk with people, commonly subject matter experts believe that conveying the facts will be enough to allow people to assess a risk and respond rationally to that risk. Because of this expectation, experts often become exasperated by the seemingly illogical way people assess personal risk and choose to manage that risk. In crisis situations when the risk information is less defined and choices must be made within impossible time constraints, the thought processes may be even more susceptible to faulty heuristics. Understanding the perception of risk is essential to understanding why the public becomes more or less upset by events. This article explores the psychological underpinnings of risk assessment within emotionally laden events and the risk communication practices that may facilitate subject matter experts to provide the facts in a manner so they can be more certain those facts are being heard. Source credibility is foundational to risk communication practices. The public meeting is one example in which these best practices can be exercised. Risks are risky because risk perceptions differ and the psychosocial environment in which risk is discussed complicates making risk decisions. Experts who want to influence the actions of the public related to a threat or risk should understand that decisions often involve emotional as well as logical components. The media and other social entities will also influence the risk context. The Center for Disease Control and Prevention's crisis and emergency-risk communication (CERC) principles are intended to increase credibility and recognize emotional components of an event. During a risk event, CERC works to calm emotions and increase trust which can help people apply the expertise being offered by response officials. Copyright © 2011. Published by Elsevier Inc. JF - Toxicology and applied pharmacology AU - Reynolds, Barbara J AD - U. S. Centers for Disease Control and Prevention, 1600 Clifton Road, N.E, Atlanta, Georgia 30333, USA. Bsr0@cdc.gov Y1 - 2011/07/15/ PY - 2011 DA - 2011 Jul 15 SP - 206 EP - 214 VL - 254 IS - 2 KW - Index Medicus KW - United States KW - Public Health -- methods KW - Humans KW - Time Factors KW - Public Health -- standards KW - Risk Assessment KW - Emotions KW - Centers for Disease Control and Prevention (U.S.) -- standards KW - Perception KW - Communication UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/876185889?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+applied+pharmacology&rft.atitle=When+the+facts+are+just+not+enough%3A+credibly+communicating+about+risk+is+riskier+when+emotions+run+high+and+time+is+short.&rft.au=Reynolds%2C+Barbara+J&rft.aulast=Reynolds&rft.aufirst=Barbara&rft.date=2011-07-15&rft.volume=254&rft.issue=2&rft.spage=206&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+applied+pharmacology&rft.issn=1096-0333&rft_id=info:doi/10.1016%2Fj.taap.2010.10.023 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-09-06 N1 - Date created - 2011-07-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.taap.2010.10.023 ER - TY - JOUR T1 - Assessing the toxic effects of ethylene glycol ethers using Quantitative Structure Toxicity Relationship models. AN - 876185864; 21034757 AB - Experimental determination of toxicity profiles consumes a great deal of time, money, and other resources. Consequently, businesses, societies, and regulators strive for reliable alternatives such as Quantitative Structure Toxicity Relationship (QSTR) models to fill gaps in toxicity profiles of compounds of concern to human health. The use of glycol ethers and their health effects have recently attracted the attention of international organizations such as the World Health Organization (WHO). The board members of Concise International Chemical Assessment Documents (CICAD) recently identified inadequate testing as well as gaps in toxicity profiles of ethylene glycol mono-n-alkyl ethers (EGEs). The CICAD board requested the ATSDR Computational Toxicology and Methods Development Laboratory to conduct QSTR assessments of certain specific toxicity endpoints for these chemicals. In order to evaluate the potential health effects of EGEs, CICAD proposed a critical QSTR analysis of the mutagenicity, carcinogenicity, and developmental effects of EGEs and other selected chemicals. We report here results of the application of QSTRs to assess rodent carcinogenicity, mutagenicity, and developmental toxicity of four EGEs: 2-methoxyethanol, 2-ethoxyethanol, 2-propoxyethanol, and 2-butoxyethanol and their metabolites. Neither mutagenicity nor carcinogenicity is indicated for the parent compounds, but these compounds are predicted to be developmental toxicants. The predicted toxicity effects were subjected to reverse QSTR (rQSTR) analysis to identify structural attributes that may be the main drivers of the developmental toxicity potential of these compounds. Copyright © 2010. Published by Elsevier Inc. JF - Toxicology and applied pharmacology AU - Ruiz, Patricia AU - Mumtaz, Moiz AU - Gombar, Vijay AD - Computational Toxicology Methods Development Laboratory, Division of Toxicology and Environmental Medicine, Agency for Toxic Substances and Disease Registry, Atlanta, GA 30333, USA. pruiz@cdc.gov Y1 - 2011/07/15/ PY - 2011 DA - 2011 Jul 15 SP - 198 EP - 205 VL - 254 IS - 2 KW - Ethers KW - 0 KW - Ethylene Glycol KW - FC72KVT52F KW - Index Medicus KW - Rats KW - Animals KW - Mutagenicity Tests -- methods KW - Mice KW - Male KW - Female KW - Ethylene Glycol -- chemistry KW - Quantitative Structure-Activity Relationship KW - Ethylene Glycol -- toxicity KW - Ethylene Glycol -- pharmacokinetics KW - Models, Biological UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/876185864?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+applied+pharmacology&rft.atitle=Assessing+the+toxic+effects+of+ethylene+glycol+ethers+using+Quantitative+Structure+Toxicity+Relationship+models.&rft.au=Ruiz%2C+Patricia%3BMumtaz%2C+Moiz%3BGombar%2C+Vijay&rft.aulast=Ruiz&rft.aufirst=Patricia&rft.date=2011-07-15&rft.volume=254&rft.issue=2&rft.spage=198&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+applied+pharmacology&rft.issn=1096-0333&rft_id=info:doi/10.1016%2Fj.taap.2010.10.024 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-09-06 N1 - Date created - 2011-07-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.taap.2010.10.024 ER - TY - JOUR T1 - Comparative evaluation of automated and manual commercial DNA extraction methods for detection of Francisella tularensis DNA from suspensions and spiked swabs by real-time polymerase chain reaction AN - 904487089; 15165689 AB - This study evaluated commercial automated and manual DNA extraction methods for the isolation of Francisella tularensis DNA suitable for real-time polymerase chain reaction (PCR) analysis from cell suspensions and spiked cotton, foam, and polyester swabs. Two automated methods, the MagNA Pure Compact and the QIAcube, were compared to 4 manual methods, the IT 1-2-3 DNA sample purification kit, the MasterPure Complete DNA and RNA purification kit, the QIAamp DNA blood mini kit, and the UltraClean Microbial DNA isolation kit. The methods were compared using 6 F. tularensis strains representing the 2 subspecies which cause the majority of reported cases of tularemia in humans. Cell viability testing of the DNA extracts showed that all 6 extraction methods efficiently inactivated F. tularensis at concentrations of less than or equal to 106 CFU/mL. Real-time PCR analysis using a multitarget 5' nuclease assay for F. tularensis revealed that the PCR sensitivity was equivalent using DNA extracted by the 2 automated methods and the manual MasterPure and QIAamp methods. These 4 methods resulted in significantly better levels of detection from bacterial suspensions and performed equivalently for spiked swab samples than the remaining 2. This study identifies optimal DNA extraction methods for processing swab specimens for the subsequent detection of F. tularensis DNA using real-time PCR assays. Furthermore, the results provide diagnostic laboratories with the option to select from 2 automated DNA extraction methods as suitable alternatives to manual methods for the isolation of DNA from F. tularensis. JF - Diagnostic Microbiology and Infectious Disease AU - Dauphin, Leslie A AU - Walker, Roblena E AU - Petersen, Jeannine M AU - Bowen, Michael D AD - Bioterrorism Rapid Response and Advanced Technology (BRRAT) Laboratory, Laboratory Preparedness and Response Branch (LPRB), Division of Preparedness and Emerging Infections (DPEI), Centers for Disease Control and Prevention (CDC), Atlanta, GA 30333, USA, ldauphin@cdc.gov Y1 - 2011/07// PY - 2011 DA - July 2011 SP - 299 EP - 306 PB - Elsevier B.V., Box 882 New York NY 10159 United States VL - 70 IS - 3 SN - 0732-8893, 0732-8893 KW - Microbiology Abstracts B: Bacteriology; Biochemistry Abstracts 2: Nucleic Acids KW - Francisella tularensis KW - DNA extraction KW - Tularemia KW - Real-time PCR KW - Bioterrorism KW - Cell suspensions KW - polyesters KW - Cotton KW - Automation KW - Nuclease KW - Foams KW - Blood KW - RNA KW - Colony-forming cells KW - Polymerase chain reaction KW - Purification KW - J 02400:Human Diseases KW - N 14810:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/904487089?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Diagnostic+Microbiology+and+Infectious+Disease&rft.atitle=Comparative+evaluation+of+automated+and+manual+commercial+DNA+extraction+methods+for+detection+of+Francisella+tularensis+DNA+from+suspensions+and+spiked+swabs+by+real-time+polymerase+chain+reaction&rft.au=Dauphin%2C+Leslie+A%3BWalker%2C+Roblena+E%3BPetersen%2C+Jeannine+M%3BBowen%2C+Michael+D&rft.aulast=Dauphin&rft.aufirst=Leslie&rft.date=2011-07-01&rft.volume=70&rft.issue=3&rft.spage=299&rft.isbn=&rft.btitle=&rft.title=Diagnostic+Microbiology+and+Infectious+Disease&rft.issn=07328893&rft_id=info:doi/10.1016%2Fj.diagmicrobio.2011.02.010 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2016-07-07 N1 - SubjectsTermNotLitGenreText - Cell suspensions; Blood; Tularemia; polyesters; Cotton; RNA; Colony-forming cells; Nuclease; Automation; Polymerase chain reaction; Foams; Purification; Francisella tularensis DO - http://dx.doi.org/10.1016/j.diagmicrobio.2011.02.010 ER - TY - JOUR T1 - The Epidemiology of Fatal Occupational Traumatic Brain Injury in the U.S. AN - 879476349; 15128674 AB - A cross-sectional analysis of the Census of Fatal Occupational Injury database was performed. Both the Occupational Injury and Illness Classification System nature of injury codes and body part codes were used to define TBIs. Fatality rates were calculated using denominators derived from the Current Population Survey. Fatality rates were compared among industries, cause of death, and demographics with rate ratios (RRs) and 95% CIs. Poisson regression was used to assess trends in fatality rates. Data were analyzed in 2009-2010. Results: Nearly 7300 occupational TBI deaths occurred between 2003 and 2008, for an average fatality rate of 0.8 per 100,000 workers per year. The leading causes of occupational TBI death were as follows: motor vehicle (31%); falls (29%); assaults and violent acts (20%); and contact with objects/equipment (18%). Fatality rates were 15 times higher in men compared with women (RR=15, 95% CI=13.7, 16.3). Workers aged =65 years experienced the highest TBI fatality rate of all age groups (2.5 per 100,000 per year). Construction, transportation, and agriculture/forestry/fishing industries recorded nearly half of all TBI fatalities (n=1828, n=825, n=761, respectively). Occupational TBI death rates declined 23% over the 6-year period (p0.0001). Conclusions: This study provides the first national profile of fatal TBIs occurring in the U.S. workplace. Prevention efforts should be directed at those industries with the highest frequency and/or highest risk. The construction industry had the highest number of TBIs, and the agriculture, forestry, and fishing industry had the highest rates. Additionally, workers aged 65 years in all industries would be a good target for future prevention efforts. JF - American Journal of Preventive Medicine AU - Tiesman, Hope M AU - Konda, Srinivas AU - Bell, Jennifer L AD - National Institute for Occupational Safety and Health, Division of Safety Research, Analysis and Field Evaluations Branch, Morgantown, West Virginia, htiesman@cdc.gov Y1 - 2011/07// PY - 2011 DA - Jul 2011 SP - 61 EP - 67 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 41 IS - 1 SN - 0749-3797, 0749-3797 KW - CSA Neurosciences Abstracts; Health & Safety Science Abstracts; Risk Abstracts KW - census KW - Classification systems KW - Agriculture KW - Mortality KW - Age KW - Data processing KW - Injuries KW - Motor vehicles KW - Occupational safety KW - agriculture KW - Demography KW - Databases KW - Workers KW - USA KW - Transportation KW - Epidemiology KW - Risk factors KW - prevention KW - Census KW - fishing KW - Traumatic brain injury KW - Forestry KW - H 1000:Occupational Safety and Health KW - R2 23060:Medical and environmental health KW - N3 11027:Neurology & neuropathology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/879476349?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=The+Epidemiology+of+Fatal+Occupational+Traumatic+Brain+Injury+in+the+U.S.&rft.au=Tiesman%2C+Hope+M%3BKonda%2C+Srinivas%3BBell%2C+Jennifer+L&rft.aulast=Tiesman&rft.aufirst=Hope&rft.date=2011-07-01&rft.volume=41&rft.issue=1&rft.spage=61&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2011.03.007 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-07-01 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - Agriculture; Classification systems; Age; Data processing; Motor vehicles; Demography; Workers; Databases; Epidemiology; Risk factors; Census; Traumatic brain injury; Forestry; census; Mortality; Transportation; Injuries; Occupational safety; agriculture; prevention; fishing; USA DO - http://dx.doi.org/10.1016/j.amepre.2011.03.007 ER - TY - JOUR T1 - Variability of urinary concentrations of bisphenol A in spot samples, first morning voids, and 24-hour collections. AN - 874485262; 21406337 AB - Human exposure to bisphenol A (BPA) is widespread. After exposure, BPA is rapidly metabolized and eliminated in urine. Therefore, there is considerable within-person and between-person variability of BPA concentrations in spot urine samples. However, no information exists on the within-day variability of urinary BPA concentrations. We examined the between-person and within-person and between-day and within-day variability in the urinary BPA concentrations of eight adults who collected all voids for 1 week to investigate the impact of sampling strategy in the exposure assessment of BPA using spot, first morning, or 24-hr urine collections. We determined the urinary concentrations of BPA using on-line solid-phase extraction coupled to isotope dilution high-performance liquid chromatography/tandem mass spectrometry. The between-day and within-person variability was the primary contributor to the total variance both for first morning voids (77%) and 24-hr urine collections (88%). For the spot collections, we observed considerable within-day variance (70%), which outweighed the between-person (9%) and between-day and within-person (21%) variances. Regardless of the type of void (spot, first morning, 24-hr collection), urinary BPA concentrations for a given adult changed considerably--both within a day and for the 7 days of the study period. Single 24-hr urine collections accurately reflect daily exposure but can misrepresent variability in daily exposures over time. Of interest, when the population investigated is sufficiently large and samples are randomly collected relative to meal ingestion times and bladder emptying times, the single spot-sampling approach may adequately reflect the average exposure of the population to BPA. JF - Environmental health perspectives AU - Ye, Xiaoyun AU - Wong, Lee-Yang AU - Bishop, Amber M AU - Calafat, Antonia M AD - Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA. xay5@cdc.gov Y1 - 2011/07// PY - 2011 DA - July 2011 SP - 983 EP - 988 VL - 119 IS - 7 KW - Benzhydryl Compounds KW - 0 KW - Biomarkers KW - Environmental Pollutants KW - Phenols KW - bisphenol A KW - MLT3645I99 KW - Index Medicus KW - Mass Spectrometry KW - Circadian Rhythm KW - Chromatography, Gas KW - Humans KW - Adult KW - Biomarkers -- urine KW - Middle Aged KW - Georgia KW - Environmental Pollutants -- urine KW - Solid Phase Extraction KW - Time Factors KW - Male KW - Female KW - Environmental Monitoring -- methods KW - Chromatography, High Pressure Liquid KW - Environmental Exposure KW - Phenols -- urine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/874485262?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+health+perspectives&rft.atitle=Variability+of+urinary+concentrations+of+bisphenol+A+in+spot+samples%2C+first+morning+voids%2C+and+24-hour+collections.&rft.au=Ye%2C+Xiaoyun%3BWong%2C+Lee-Yang%3BBishop%2C+Amber+M%3BCalafat%2C+Antonia+M&rft.aulast=Ye&rft.aufirst=Xiaoyun&rft.date=2011-07-01&rft.volume=119&rft.issue=7&rft.spage=983&rft.isbn=&rft.btitle=&rft.title=Environmental+health+perspectives&rft.issn=1552-9924&rft_id=info:doi/10.1289%2Fehp.1002701 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-10-24 N1 - Date created - 2011-07-01 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Environ Health Perspect. 2007 Jan;115(1):116-21 [17366830] Anal Bioanal Chem. 2005 Oct;383(4):638-44 [16132150] Environ Health Perspect. 2008 Jan;116(1):39-44 [18197297] Environ Res. 2008 Feb;106(2):257-69 [17976571] Environ Health Perspect. 2008 Feb;116(2):173-8 [18288314] Toxicol Lett. 2008 Jul 10;179(3):155-62 [18579321] Reprod Toxicol. 2008 Aug;25(4):413-9 [18577445] Stat Med. 2008 Sep 10;27(20):4094-106 [18344178] Environ Res. 2009 Jul;109(5):629-33 [19426969] Philos Trans R Soc Lond B Biol Sci. 2009 Jul 27;364(1526):2063-78 [19528056] Environ Res. 2009 Aug;109(6):734-7 [19463991] Environ Res. 2009 Aug;109(6):797-801 [19464675] Int J Hyg Environ Health. 2009 Nov;212(6):685-92 [19729343] Environ Health Perspect. 2009 Dec;117(12):1945-52 [20049216] Environ Health Perspect. 2010 Aug;118(8):1055-70 [20338858] J Expo Sci Environ Epidemiol. 2010 Sep;20(6):526-35 [19707251] Environ Health Perspect. 2010 Dec;118(12):1748-54 [20797930] Environ Health Perspect. 2011 Jan;119(1):131-7 [21205581] Environ Res. 2011 Jan;111(1):143-8 [20970783] Chem Res Toxicol. 2002 Oct;15(10):1281-7 [12387626] Environ Health Perspect. 2003 Jan;111(1):101-4 [12515686] Arch Environ Contam Toxicol. 2003 May;44(4):546-51 [12712285] Cell Tissue Res. 2004 Jan;315(1):119-24 [14557871] J Expo Anal Environ Epidemiol. 2005 Mar;15(2):164-71 [15187987] Environ Health Perspect. 2005 Apr;113(4):391-5 [15811827] Anal Chem. 2005 Aug 15;77(16):5407-13 [16097788] J Expo Sci Environ Epidemiol. 2007 Jul;17(4):350-7 [16788681] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1289/ehp.1002701 ER - TY - JOUR T1 - Supplementary Immunization Activities to Achieve Measles Elimination: Experience of the European Region AN - 1627968625; 20933480 AB - Background. Supplementary immunization activities (SIAs) using measles-containing vaccine (MCV) have had a substantial impact on reducing mortality associated with measles worldwide. Methods. To assess impact of SIAs on measles incidence in the World Health Organization European Region and their role at the final stages of measles elimination efforts in Europe, we reviewed information on SIAs, measles surveillance, and routine vaccination coverage during 2000-2009. Results. During 2000-2009, >57 million persons received MCV through SIAs in 16 countries. The Region primarily focused on catch-up campaigns with wider target age groups than in other regions and subsequently relied on routine vaccination rather than periodic follow-up SIAs for the second MCV dose. In addition, the concept of SIAs has been expanded from short-term (<30 days) mass campaigns implemented in other regions to incorporate vaccination efforts over longer periods and outbreak response vaccination. In 2009, 14 of 16 countries that conducted SIAs reported no measles cases or <1 case per 1,000,000 population, reflecting the post-SIA decrease in incidence. Conclusions. SIAs have made a substantial contribution to the success of measles elimination efforts and will likely remain an important strategy for interrupting measles virus transmission in the European Region, although specific approaches will vary by country. JF - Journal of Infectious Diseases AU - Khetsuriani, Nino AU - Deshevoi, Sergei AU - Goel, Ajay AU - Spika, John AU - Martin, Rebecca AU - Emiroglu, Nedret AD - Global Immunization Division, National Center for Immunization and Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd, MS-05, Atlanta, Georgia 30033, nck7@cdc.gov Y1 - 2011/07/01/ PY - 2011 DA - 2011 Jul 01 SP - S343 EP - S352 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 204 SN - 0022-1899, 0022-1899 KW - Immunology Abstracts; Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Mortality KW - Age KW - Measles KW - Europe KW - Measles virus KW - Vaccination KW - Immunization KW - Disease transmission KW - Infectious diseases KW - Reviews KW - Age groups KW - Outbreaks KW - Vaccines KW - V 22490:Miscellaneous KW - F 06910:Microorganisms & Parasites KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1627968625?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Supplementary+Immunization+Activities+to+Achieve+Measles+Elimination%3A+Experience+of+the+European+Region&rft.au=Khetsuriani%2C+Nino%3BDeshevoi%2C+Sergei%3BGoel%2C+Ajay%3BSpika%2C+John%3BMartin%2C+Rebecca%3BEmiroglu%2C+Nedret&rft.aulast=Khetsuriani&rft.aufirst=Nino&rft.date=2011-07-01&rft.volume=204&rft.issue=&rft.spage=S343&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjir074 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-11-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Mortality; Age; Measles; Reviews; Vaccines; Vaccination; Disease transmission; Infectious diseases; Age groups; Outbreaks; Immunization; Measles virus; Europe DO - http://dx.doi.org/10.1093/infdis/jir074 ER - TY - JOUR T1 - Improving Global Virologic Surveillance for Measles and Rubella AN - 1627968264; 20933483 AB - An important aspect of laboratory surveillance for measles and rubella is the genetic characterization of circulating wild-type viruses to support molecular epidemiologic studies and to track transmission pathways. Virologic surveillance that is sufficient to document the interruption of transmission of measles and rubella viruses will be an essential criterion for verification of elimination. Laboratories in the World Health Organization (WHO) Measles and Rubella Laboratory Network have worked to improve and expand virologic surveillance as many regions move toward elimination of measles and rubella/congenital rubella syndrome. As countries approach elimination, it will be necessary to obtain genetic information from as many chains of transmission as possible. In addition, baseline virologic surveillance, especially for rubella, needs to be improved in many countries. This report contains a summary of recent improvements to the methods used for virologic surveillance. JF - Journal of Infectious Diseases AU - Rota, Paul A AU - Brown, Kevin E AU - Hubschen, Judith M AU - Muller, Claude P AU - Icenogle, Joseph AU - Chen, Min-Hsin AU - Bankamp, Bettina AU - Kessler, Julia R AU - Brown, David W AU - Bellini, William J AU - Featherstone, David AD - Centers for Disease Control and Prevention, 1600 Clifton Rd, MS-C-22, Atlanta, GA 30333, prota@cdc.gov Y1 - 2011/07/01/ PY - 2011 DA - 2011 Jul 01 SP - S506 EP - S513 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 204 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Infectious diseases KW - Measles KW - Congenital rubella KW - Viruses KW - Rubella KW - H 12000:Epidemiology and Public Health KW - V 22310:Genetics, Taxonomy & Structure UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1627968264?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Improving+Global+Virologic+Surveillance+for+Measles+and+Rubella&rft.au=Rota%2C+Paul+A%3BBrown%2C+Kevin+E%3BHubschen%2C+Judith+M%3BMuller%2C+Claude+P%3BIcenogle%2C+Joseph%3BChen%2C+Min-Hsin%3BBankamp%2C+Bettina%3BKessler%2C+Julia+R%3BBrown%2C+David+W%3BBellini%2C+William+J%3BFeatherstone%2C+David&rft.aulast=Rota&rft.aufirst=Paul&rft.date=2011-07-01&rft.volume=204&rft.issue=&rft.spage=S506&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjir117 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-11-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Congenital rubella; Measles; Rubella; Infectious diseases; Viruses DO - http://dx.doi.org/10.1093/infdis/jir117 ER - TY - JOUR T1 - Should Outbreak Response Immunization Be Recommended for Measles Outbreaks in Middle- and Low-Income Countries? An Update AN - 1627957839; 20933470 AB - Background. Measles caused mortality in > 164,000 children in 2008, with most deaths occurring during outbreaks. Nonetheless, the impact and desirability of conducting measles outbreak response immunization (ORI) in middle- and low-income countries has been controversial. World Health Organization guidelines published in 1999 recommended against ORI in such settings, although recently these guidelines have been reversed for countries with measles mortality reduction goals. Methods. We searched literature published during 1995-2009 for papers reporting on measles outbreaks. Papers identified were reviewed by 2 reviewers to select those that mentioned ORI. World Bank classification of country income was used to identify reports of outbreaks in middle- and low-income countries. Results. We identified a total of 485 articles, of which 461 (95%) were available. Thirty-eight of these papers reported on a total of 38 outbreaks in which ORI was used. ORI had a clear impact in 16 (42%) of these outbreaks. In the remaining outbreaks, we were unable to independently assess the impact of ORI. Conclusions. These findings generally support ORI in middle- and low-income countries. However, the decision to conduct ORI and the nature and extent of the vaccination response need to be made on a case-by-case basis. JF - Journal of Infectious Diseases AU - Cairns, K Lisa AU - Perry, Robert T AU - Ryman, Tove K AU - Nandy, Robin K AU - Grais, Rebecca F AD - Global Immunization Division, US Centers for Disease Control and Prevention, Atlanta, Georgia, kfc4@cdc.gov Y1 - 2011/07/01/ PY - 2011 DA - 2011 Jul 01 SP - S35 EP - S46 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 204 SN - 0022-1899, 0022-1899 KW - Immunology Abstracts; Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Mortality KW - Measles KW - Guidelines KW - Socioeconomics KW - Children KW - Vaccination KW - Immunization KW - Income KW - Infectious diseases KW - Classification KW - Reviews KW - Outbreaks KW - Vaccines KW - F 06910:Microorganisms & Parasites KW - H 0500:General KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1627957839?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Should+Outbreak+Response+Immunization+Be+Recommended+for+Measles+Outbreaks+in+Middle-+and+Low-Income+Countries%3F+An+Update&rft.au=Cairns%2C+K+Lisa%3BPerry%2C+Robert+T%3BRyman%2C+Tove+K%3BNandy%2C+Robin+K%3BGrais%2C+Rebecca+F&rft.aulast=Cairns&rft.aufirst=K&rft.date=2011-07-01&rft.volume=204&rft.issue=&rft.spage=S35&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjir072 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-11-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Mortality; Classification; Measles; Reviews; Children; Vaccination; Infectious diseases; Guidelines; Socioeconomics; Vaccines; Outbreaks; Immunization; Income DO - http://dx.doi.org/10.1093/infdis/jir072 ER - TY - JOUR T1 - Prevalence and genetic diversity of candidate vaccine antigens among invasive Neisseria meningitidis isolates in the United States AN - 874194247; 15004468 AB - Neisseria meningitidis (Nm) serogroups B, C and Y are the major causes of meningococcal diseases in the United States. NmB accounts for [not, vert, similar]1/3 of the disease but no licensed vaccine is yet available. Two candidate vaccines are being developed specifically to target NmB, but may also provide protection against other serogroups. To assess the potential impact of these vaccines on NmB and other serogroups causing disease in the US, we determined the prevalence, genetic diversity and epidemiological characteristics of three candidate antigen genes in Nm isolates collected through Active Bacterial Core surveillance (ABCs), a population-based active surveillance program. fHbp was detected in all NmB, NmY and NmW135 isolates. Eleven NmC isolates contain fHbp with a single base-pair deletion creating a frame shift in the C-terminal region. Among NmB, 59% were FHbp subfamily/variant B/v1 and 41% A/v2-3. Among NmC and NmY, 39% and 3% were B/v1, respectively. nadA was detected in 39% of NmB, 61% of NmC and 4% of NmY. Among isolates tested, nhbA was present in all NmB and 96% of non-B. For the subset of strains sequenced for NadA and NhbA, pairwise identity was greater than 93% and 78%, respectively. The proportion of FHbp subfamily/variant was different between ABCs site and year, but no linear temporal trend was observed. Although assessment of the vaccine coverage also requires understanding of the antigen expression and the ability to induce bactericidal activity, our finding that all isolates contain one or more antigen genes suggests these candidate vaccines may protect against multiple Nm serogroups. JF - Vaccine AU - Wang, Xin AU - Cohn, Amanda AU - Comanducci, Maurizio AU - Andrew, Lubomira AU - Zhao, Xin AU - MacNeil, Jessica R AU - Schmink, Susanna AU - Muzzi, Alessandro AU - Bambini, Stefania AU - Rappuoli, Rino AU - Pizza, Mariagrazia AU - Murphy, Ellen AU - Hoiseth, Susan K AU - Jansen, Kathrin U AU - Anderson, Annaliesa S AU - Harrison, Lee H AU - Clark, Thomas A AU - Messonnier, Nancy E AU - Mayer, Leonard W AD - Meningitis and Vaccine Preventable Disease Branch, Division of Bacterial Diseases, National Center of Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, United States, gqe8@cdc.gov gqe8@cdc.gov gqe8@cdc.gov gqe8@cdc.gov gqe8@cdc.gov gqe8@cdc.gov gqe8@cdc.gov gqe8@cdc.gov gqe8@cdc.gov gqe8@cdc.gov Y1 - 2011/06/24/ PY - 2011 DA - 2011 Jun 24 SP - 4739 EP - 4744 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 29 IS - 29-30 SN - 0264-410X, 0264-410X KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Gene deletion KW - meningococcal disease KW - Genetic diversity KW - Neisseria meningitidis KW - Vaccines KW - Bactericidal activity KW - F 06905:Vaccines KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/874194247?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Prevalence+and+genetic+diversity+of+candidate+vaccine+antigens+among+invasive+Neisseria+meningitidis+isolates+in+the+United+States&rft.au=Wang%2C+Xin%3BCohn%2C+Amanda%3BComanducci%2C+Maurizio%3BAndrew%2C+Lubomira%3BZhao%2C+Xin%3BMacNeil%2C+Jessica+R%3BSchmink%2C+Susanna%3BMuzzi%2C+Alessandro%3BBambini%2C+Stefania%3BRappuoli%2C+Rino%3BPizza%2C+Mariagrazia%3BMurphy%2C+Ellen%3BHoiseth%2C+Susan+K%3BJansen%2C+Kathrin+U%3BAnderson%2C+Annaliesa+S%3BHarrison%2C+Lee+H%3BClark%2C+Thomas+A%3BMessonnier%2C+Nancy+E%3BMayer%2C+Leonard+W&rft.aulast=Wang&rft.aufirst=Xin&rft.date=2011-06-24&rft.volume=29&rft.issue=29-30&rft.spage=4739&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/10.1016%2Fj.vaccine.2011.04.092 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-06-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Gene deletion; meningococcal disease; Genetic diversity; Vaccines; Bactericidal activity; Neisseria meningitidis DO - http://dx.doi.org/10.1016/j.vaccine.2011.04.092 ER - TY - CPAPER T1 - Household Water Treatment in the Acute Emergency Situation - Lessons for Four Emergencies T2 - 130th Annual Conference and Exposition of the American Water Works Association (ACE 11) AN - 1313020778; 6065367 JF - 130th Annual Conference and Exposition of the American Water Works Association (ACE 11) AU - Lantagne, Daniele Y1 - 2011/06/12/ PY - 2011 DA - 2011 Jun 12 KW - Water treatment KW - Households KW - Emergencies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313020778?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=130th+Annual+Conference+and+Exposition+of+the+American+Water+Works+Association+%28ACE+11%29&rft.atitle=Household+Water+Treatment+in+the+Acute+Emergency+Situation+-+Lessons+for+Four+Emergencies&rft.au=Lantagne%2C+Daniele&rft.aulast=Lantagne&rft.aufirst=Daniele&rft.date=2011-06-12&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=130th+Annual+Conference+and+Exposition+of+the+American+Water+Works+Association+%28ACE+11%29&rft.issn=&rft_id=info:doi/ L2 - http://apps.awwa.org/ebusmain/default.aspx?tabid=265&viewer=dates&meetingid=A11 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - JOUR T1 - Bridging Populations-Sexual Risk Behaviors and HIV Prevalence in Clients and Partners of Female Sex Workers, Bangkok, Thailand 2007 AN - 954659544; 16419325 AB - The aim of this study is to estimate HIV prevalence and assess sexual behaviors in a high-risk and difficult-to-reach population of clients of female sex workers (FSWs). A modified variation of respondent-driven sampling was conducted among FSWs in Bangkok, where FSWs recruited 3 FSW peers, 1 client, and 1 nonpaying partner. After informed consent was obtained, participants completed a questionnaire, were HIV-tested, and were asked to return for results. Analyses were weighted to control for the design of the survey. Among 540 FSWs, 188 (35%) recruited 1 client, and 88 (16%) recruited 1 nonpaying partner. Clients' median age was 38 years. HIV prevalence was 20% and was associated with younger age at first sexual experience [relative risk (RR)=3.10, 95% confidence interval (CI) 1.16-8.24] and condom use during last sexual encounter with regular partner (RR=3.97, 95% CI 1.09-14.61). Median age of nonpaying partners was 34 years, and HIV prevalence was 15.1%. There were 56 discordant FSW-client pairs and 14 discordant FSW-nonpaying partner pairs. Condom use was relatively high among discordant FSW-client pairs (90.1%) compared to discordant FSW-nonpaying partner pairs (18.7%). Results suggest that sexual partners of FSWs have a high HIV prevalence and can be a bridge for HIV transmission to other populations. Findings also highlight the importance of initiating surveillance and targeted programs for FSW partners, and demonstrate a recruitment method for hard-to-reach populations. JF - Journal of Urban Health AU - Shah, Neha S AU - Shiraishi, Ray W AU - Subhachaturas, Wonchart AU - Anand, Abhijeet AU - Whitehead, Sara J AU - Tanpradech, Suvimon AU - Manopaiboon, Chomnad AU - Sabin, Keith M AU - Fox, Kimberley K AU - Kim, Andrea Y AD - Global AIDS Program, National Center for HIV, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA, Nshah6@cdc.gov Y1 - 2011/06// PY - 2011 DA - Jun 2011 SP - 533 EP - 544 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 88 IS - 3 SN - 1099-3460, 1099-3460 KW - Risk Abstracts KW - sexual behavior KW - Age KW - disease transmission KW - Behavior KW - Human immunodeficiency virus KW - condoms KW - recruitment KW - Thailand, Chacoengsao Prov., Bangkok KW - Females KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/954659544?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Urban+Health&rft.atitle=Bridging+Populations-Sexual+Risk+Behaviors+and+HIV+Prevalence+in+Clients+and+Partners+of+Female+Sex+Workers%2C+Bangkok%2C+Thailand+2007&rft.au=Shah%2C+Neha+S%3BShiraishi%2C+Ray+W%3BSubhachaturas%2C+Wonchart%3BAnand%2C+Abhijeet%3BWhitehead%2C+Sara+J%3BTanpradech%2C+Suvimon%3BManopaiboon%2C+Chomnad%3BSabin%2C+Keith+M%3BFox%2C+Kimberley+K%3BKim%2C+Andrea+Y&rft.aulast=Shah&rft.aufirst=Neha&rft.date=2011-06-01&rft.volume=88&rft.issue=3&rft.spage=533&rft.isbn=&rft.btitle=&rft.title=Journal+of+Urban+Health&rft.issn=10993460&rft_id=info:doi/10.1007%2Fs11524-010-9542-5 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - sexual behavior; Age; Behavior; disease transmission; Human immunodeficiency virus; condoms; recruitment; Females; Thailand, Chacoengsao Prov., Bangkok DO - http://dx.doi.org/10.1007/s11524-010-9542-5 ER - TY - JOUR T1 - Replication of the Primary Dog Kidney-53 Dengue 2 Virus Vaccine Candidate in Aedes aegypti Is Modulated by a Mutation in the 5' Untranslated Region and Amino Acid Substitutions in Nonstructural Proteins 1 and 3 AN - 920796791; 16154956 AB - Previous studies have demonstrated reduced replication of the cell culture-adapted Dengue-2 virus (DENV-2) vaccine candidate, primary dog kidney (PDK)-53, compared with the parental DENV-2 strain, 16681, in C6/36 cells. Various DENV-2 mutants incorporating PDK-53 substitutions singly and in combination into the 16681 genetic backbone were used to identify the genetic basis for impaired replication of the vaccine candidate in vitro in Aedes aegypti cell culture (Aag2 cells) as well as the reduced in vivo infectivity and transmissibility within Ae. aegypti infected by intrathoracic inoculation. 5' untranslated region (UTR-c57t) and nonstructural protein 1 (NS1-G53D) mutations were required to completely attenuate in vitro replication. In contrast, incorporation of the PDK-53-specific NS3-250V mutation into the 16681 virus resulted in reduced replication in mosquitoes but had no effect on In vitro replication. Further, reversion of the PDK-53 NS3-250 site to that of the wild-type 16681 virus (NS3-V250E) failed to increase either in vitro or in vivo replication. Intrathoracic inoculation of Ae. aegypti with mutants containing the PDK-53 NS1 substitution exhibited in vivo replication indistinguishable from the parental PDK-53 virus, implicating this mutation as the dominant determinant for impaired mosquito replication of the PDK-53 candidate; however, further attenuation of in vivo replication was magnified in mutants including the additional 5'UTR-c57t mutation. JF - Vector Borne and Zoonotic Diseases AU - Brault, A C AU - Kinney, R M AU - Maharaj, P D AU - Green, ENG AU - Reisen, W K AU - Huang, CY-H AD - Division of Vector-Borne Infectious Diseases, U. S. Department of Health and Human Services, Centers for Disease Control and Prevention, Foothills Campus/Rampart Road, Fort Collins, CO 80521, USA, abrault@cdc.gov Y1 - 2011/06// PY - 2011 DA - June 2011 SP - 683 EP - 689 VL - 11 IS - 6 SN - 1530-3667, 1530-3667 KW - Genetics Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Entomology Abstracts; Virology & AIDS Abstracts KW - Aedes aegypti KW - Human diseases KW - Amino acid substitution KW - Amino acids KW - Replication KW - Mutations KW - Disease control KW - Vectors KW - Reversion KW - Cell culture KW - Public health KW - Disease transmission KW - Infectivity KW - Nonstructural proteins KW - Inoculation KW - Kidney KW - Vaccines KW - Dengue virus type 2 KW - Mutation KW - Aquatic insects KW - Q1 08484:Species interactions: parasites and diseases KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - V 22320:Replication KW - Q5 08524:Public health, medicines, dangerous organisms KW - G 07780:Fungi UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/920796791?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vector+Borne+and+Zoonotic+Diseases&rft.atitle=Replication+of+the+Primary+Dog+Kidney-53+Dengue+2+Virus+Vaccine+Candidate+in+Aedes+aegypti+Is+Modulated+by+a+Mutation+in+the+5%27+Untranslated+Region+and+Amino+Acid+Substitutions+in+Nonstructural+Proteins+1+and+3&rft.au=Brault%2C+A+C%3BKinney%2C+R+M%3BMaharaj%2C+P+D%3BGreen%2C+ENG%3BReisen%2C+W+K%3BHuang%2C+CY-H&rft.aulast=Brault&rft.aufirst=A&rft.date=2011-06-01&rft.volume=11&rft.issue=6&rft.spage=683&rft.isbn=&rft.btitle=&rft.title=Vector+Borne+and+Zoonotic+Diseases&rft.issn=15303667&rft_id=info:doi/10.1089%2Fvbz.2010.0150 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-02-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Human diseases; Amino acids; Mutations; Replication; Disease control; Vaccines; Aquatic insects; Disease transmission; Public health; Infectivity; Amino acid substitution; Nonstructural proteins; Kidney; Inoculation; Reversion; Vectors; Cell culture; Mutation; Aedes aegypti; Dengue virus type 2 DO - http://dx.doi.org/10.1089/vbz.2010.0150 ER - TY - JOUR T1 - General Principles of Medical Surveillance Implications for Workers Potentially Exposed to Nanomaterials AN - 876243272; 15112460 AB - Objective: As potential occupational exposure to nanomaterials becomes more prevalent, it is important that the principles of medical surveillance be considered for workers in the nanotechnology industry. Methods: The principles of medical surveillance are reviewed to further the discussion of occupational health surveillance for workers exposed to nanomaterials. Results: Because of the rapid evolution of nanotechnology, information may not be available to make a well-informed determination of all factors needed to evaluate risk of health effects from occupational exposure to nanomaterials. Conclusion: Every workplace dealing with engineered nanomaterials should conduct hazard and exposure assessments as part of an overall surveillance needs assessment for nanotechnology workers. In workplaces where risk is felt to be present, or at least cannot be ruled out, initiation of medical surveillance is prudent to protect workers' health. JF - Journal of Occupational and Environmental Medicine AU - Trout, D B AD - DSHEFS, NIOSH, R-12, 4676 Columbia Parkway, Cincinnati, OH 45226, USA, dtrout@cdc.gov Y1 - 2011/06// PY - 2011 DA - Jun 2011 SP - S22 EP - S24 VL - 53 SN - 1076-2752, 1076-2752 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Reviews KW - Occupational exposure KW - nanotechnology KW - Occupational health KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/876243272?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=General+Principles+of+Medical+Surveillance+Implications+for+Workers+Potentially+Exposed+to+Nanomaterials&rft.au=Trout%2C+D+B&rft.aulast=Trout&rft.aufirst=D&rft.date=2011-06-01&rft.volume=53&rft.issue=&rft.spage=S22&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e31821b1e45 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-07-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Reviews; Occupational exposure; Occupational health; nanotechnology DO - http://dx.doi.org/10.1097/JOM.0b013e31821b1e45 ER - TY - JOUR T1 - Nanomaterials and Worker Health Medical Surveillance, Exposure Registries, and Epidemiologic Research AN - 876243230; 15112456 AB - Objective: This article provides an overview of the issues that arise with medical surveillance, exposure registration, and epidemiologic research involving nanomaterial workers. Methods: An occupational health perspective is applied to detecting risks in nanomaterial workers individually and as a group. Results: General principles for medical surveillance, exposure registration, and epidemiologic research are identified. A model Nanomaterial Worker Health Study is for consideration. Conclusions: The Nanomaterial Worker Health Study can be developed as a tangible action in assuring the public that steps are being taken to learn of any adverse effects from exposure to nanomaterials. JF - Journal of Occupational and Environmental Medicine AU - Schulte, P A AU - Trout, D B AD - National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, 4676 Columbia Parkway, MS C-14, Cincinnati, OH 45226, USA, PSchulte@cdc.gov Y1 - 2011/06// PY - 2011 DA - Jun 2011 SP - S3 EP - S7 VL - 53 SN - 1076-2752, 1076-2752 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Occupational exposure KW - Occupational health KW - Side effects KW - nanotechnology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/876243230?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Nanomaterials+and+Worker+Health+Medical+Surveillance%2C+Exposure+Registries%2C+and+Epidemiologic+Research&rft.au=Schulte%2C+P+A%3BTrout%2C+D+B&rft.aulast=Schulte&rft.aufirst=P&rft.date=2011-06-01&rft.volume=53&rft.issue=&rft.spage=S3&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e31821b1b28 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-07-01 N1 - Last updated - 2012-09-24 N1 - SubjectsTermNotLitGenreText - Side effects; Occupational exposure; Occupational health; nanotechnology DO - http://dx.doi.org/10.1097/JOM.0b013e31821b1b28 ER - TY - JOUR T1 - Carbon Nanotube Risk Assessment Implications for Exposure and Medical Monitoring AN - 876239527; 15112475 AB - Objective: Quantitative risk estimates using toxicology data provide information for risk management to protect workers with potential exposure to carbon nanotubes (CNTs). Methods: Dose-response data from subchronic inhalation studies in rats were used in benchmark dose modeling. Dose was airborne mass concentration of multiwalled CNTs. Responses included pulrronary inflammation, lipoproteinosis, and fibrosis. Results: Estimated human-equivalent concentrations to the rat lowest observed adverse effect levels were similar to some workplace airborne concentrations of CNTs. Working lifetime risk estimates of early-stage adverse lung effects were more than 10% at the limit of quantification (7 mu g/m super(3)) of the National Institute for Occupational Safety and Health analytical method for measuring CNT airborne concentrations. Conclusions: Exposure monitoring and control are the primary occupational health measures to protect workers from potential exposure to CNT. Medical monitoring for early detection of occupational respiratory diseases may also be warranted. JF - Journal of Occupational and Environmental Medicine AU - Kuempel, ED AD - Education and Information Division, National Institute for Occupational Safety and Health, 4676 Columbia Pkwy, M.S. C-15, Cincinnati, OH 45226, USA, ekuempel@cdc.gov Y1 - 2011/06// PY - 2011 DA - Jun 2011 SP - S91 EP - S97 VL - 53 SN - 1076-2752, 1076-2752 KW - Toxicology Abstracts; Risk Abstracts; Pollution Abstracts; Health & Safety Science Abstracts KW - Inhalation KW - Risk assessment KW - Data processing KW - Fibrosis KW - Respiratory diseases KW - Inflammation KW - Rats KW - Carbon KW - benchmarks KW - Lung KW - Dose-response effects KW - Occupational exposure KW - Side effects KW - nanotechnology KW - P 0000:AIR POLLUTION KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/876239527?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Carbon+Nanotube+Risk+Assessment+Implications+for+Exposure+and+Medical+Monitoring&rft.au=Kuempel%2C+ED&rft.aulast=Kuempel&rft.aufirst=ED&rft.date=2011-06-01&rft.volume=53&rft.issue=&rft.spage=S91&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e31821b1f3f LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-07-01 N1 - Last updated - 2013-06-14 N1 - SubjectsTermNotLitGenreText - Risk assessment; Inhalation; Data processing; Carbon; Lung; Fibrosis; Side effects; Occupational exposure; Inflammation; Rats; benchmarks; Dose-response effects; Respiratory diseases; nanotechnology DO - http://dx.doi.org/10.1097/JOM.0b013e31821b1f3f ER - TY - JOUR T1 - Engineered Carbonaceous Nanomaterials Manufacturers in the United States Workforce Size, Characteristics, and Feasibility of Epidemiologic Studies AN - 876237610; 15112470 AB - Objective: Toxicology studies suggest that carbon nanotube (CNT) exposures may cause adverse pulmonary effects. This study identified all US engineered carbonaceous nanomaterial (ECN) manufacturers, determined workforce size and growth, and characterized the materials produced to determine the feasibility of occupational ECN exposure studies. Methods: Eligible companies were identified; information was assembled on the companies and nanomaterials they produced; and the workforce size, location, and growth were estimated. Results: Sixty-one companies manufacturing ECN in the United States were identified. These companies employed at least 620 workers; workforce growth was projected at 15% to 17% annually. Most companies produced or used CNT. Half the eligible companies provided information about material dimensions, quantities, synthesis methods, and worker exposure reduction strategies. Conclusions: Industrywide exposure assessment studies appear feasible; however, cohort studies are likely infeasible because of the small, scattered workforce. JF - Journal of Occupational and Environmental Medicine AU - Schubauer-Berigan, M K AU - Dahm, M M AU - Yencken AD - National Institute for Occupational Safety and Health; Division of Surveillance, Hazard Evaluations, and Field Studies, Industrywide Studies Branch, 4676 Columbia Parkway, MS-R15, Cincinnati, OH 45226, USA, zcg3@cdc.gov Y1 - 2011/06// PY - 2011 DA - Jun 2011 SP - S62 EP - S67 VL - 53 SN - 1076-2752, 1076-2752 KW - Health & Safety Science Abstracts; Pollution Abstracts KW - Feasibility studies KW - USA KW - Occupational exposure KW - Toxicology KW - nanotechnology KW - H 1000:Occupational Safety and Health KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/876237610?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Engineered+Carbonaceous+Nanomaterials+Manufacturers+in+the+United+States+Workforce+Size%2C+Characteristics%2C+and+Feasibility+of+Epidemiologic+Studies&rft.au=Schubauer-Berigan%2C+M+K%3BDahm%2C+M+M%3BYencken&rft.aulast=Schubauer-Berigan&rft.aufirst=M&rft.date=2011-06-01&rft.volume=53&rft.issue=&rft.spage=S62&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e31821b1e2c LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-07-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Feasibility studies; Toxicology; Occupational exposure; nanotechnology; USA DO - http://dx.doi.org/10.1097/JOM.0b013e31821b1e2c ER - TY - JOUR T1 - Exposure Registries: Overview and Utility for Nanomaterial Workers AN - 876235417; 15112466 AB - Objective: This article provides the background for consideration of exposure registries to address potential disease risks in nanomaterial workers. Methods: The history of exposure registries is reviewed with a focus on their purpose and criteria for establishment. Results: A rationale is presented for developing registries of nanomaterial workers, and unresolved obstacles and challenges are identified. These include issues on inclusion criteria, funding, potential for legal risks, access to data, confidentiality of business information, privacy, and workers' expectations. Conclusion: If society is to gain the benefits from nanotechnology, it must take precautions and demonstrate care for those, such as workers, who may be most at risk of adverse effects. Establishing exposure registries is a part of such a precautionary and caring approach. JF - Journal of Occupational and Environmental Medicine AU - Schulte, P A AU - Mundt, D J AU - Nasterlack, M AU - Mulloy, K B AU - Mundt, KA AD - National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, 4676 Columbia Parkway, MS C-14, Cincinnati, Ohio 45226, USA, PSchulte@cdc.gov Y1 - 2011/06// PY - 2011 DA - Jun 2011 SP - S42 EP - S47 VL - 53 SN - 1076-2752, 1076-2752 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Historical account KW - Reviews KW - Occupational exposure KW - Side effects KW - nanotechnology KW - H 1000:Occupational Safety and Health KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/876235417?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Exposure+Registries%3A+Overview+and+Utility+for+Nanomaterial+Workers&rft.au=Schulte%2C+P+A%3BMundt%2C+D+J%3BNasterlack%2C+M%3BMulloy%2C+K+B%3BMundt%2C+KA&rft.aulast=Schulte&rft.aufirst=P&rft.date=2011-06-01&rft.volume=53&rft.issue=&rft.spage=S42&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e31821aebed LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-07-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Historical account; Reviews; Side effects; Occupational exposure; nanotechnology DO - http://dx.doi.org/10.1097/JOM.0b013e31821aebed ER - TY - JOUR T1 - Pharmacogenetics, pharmacogenomics, and individualized medicine. AN - 863903058; 21436344 AB - Individual variability in drug efficacy and drug safety is a major challenge in current clinical practice, drug development, and drug regulation. For more than 5 decades, studies of pharmacogenetics have provided ample examples of causal relations between genotypes and drug response to account for phenotypic variations of clinical importance in drug therapy. The convergence of pharmacogenetics and human genomics in recent years has dramatically accelerated the discovery of new genetic variations that potentially underlie variability in drug response, giving birth to pharmacogenomics. In addition to the rapid accumulation of knowledge on genome-disease and genome-drug interactions, there arises the hope of individualized medicine. Here we review recent progress in the understanding of genetic contributions to major individual variability in drug therapy with focus on genetic variations of drug target, drug metabolism, drug transport, disease susceptibility, and drug safety. Challenges to future pharmacogenomics and its translation into individualized medicine, drug development, and regulation are discussed. For example, knowledge on genetic determinants of disease pathogenesis and drug action, especially those of complex disease and drug response, is not always available. Relating the many gene variations from genomic sequencing to clinical phenotypes may not be straightforward. It is often very challenging to conduct large scale, prospective studies to establish causal associations between genetic variations and drug response or to evaluate the utility and cost-effectiveness of genomic medicine. Overcoming the obstacles holds promise for achieving the ultimate goal of effective and safe medication to targeted patients with appropriate genotypes. JF - Pharmacological reviews AU - Ma, Qiang AU - Lu, Anthony Y H AD - Receptor Biology Laboratory, Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, 1095 Willowdale Rd., Morgantown, WV 26505, USA. qam1@cdc.gov Y1 - 2011/06// PY - 2011 DA - June 2011 SP - 437 EP - 459 VL - 63 IS - 2 KW - Pharmaceutical Preparations KW - 0 KW - Cytochrome P-450 Enzyme System KW - 9035-51-2 KW - Index Medicus KW - Pharmaceutical Preparations -- administration & dosage KW - Animals KW - Pharmaceutical Preparations -- metabolism KW - Polymorphism, Genetic KW - Cytochrome P-450 Enzyme System -- genetics KW - Humans KW - Drug-Related Side Effects and Adverse Reactions KW - Cytochrome P-450 Enzyme System -- metabolism KW - Drug Design KW - Drug Delivery Systems KW - Precision Medicine -- methods KW - Pharmacogenetics -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/863903058?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Pharmacological+reviews&rft.atitle=Pharmacogenetics%2C+pharmacogenomics%2C+and+individualized+medicine.&rft.au=Ma%2C+Qiang%3BLu%2C+Anthony+Y+H&rft.aulast=Ma&rft.aufirst=Qiang&rft.date=2011-06-01&rft.volume=63&rft.issue=2&rft.spage=437&rft.isbn=&rft.btitle=&rft.title=Pharmacological+reviews&rft.issn=1521-0081&rft_id=info:doi/10.1124%2Fpr.110.003533 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-08-11 N1 - Date created - 2011-04-27 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1124/pr.110.003533 ER - TY - JOUR T1 - Exposure Control Strategies in the Carbonaceous Nanomaterial Industry AN - 1020840497; 15112471 AB - Objective: Little is known about exposure control strategies currently being implemented to minimize exposures during the production or use of nanomaterials in the United States. Our goal was to estimate types and quantities of materials used and factors related to workplace exposure reductions among companies manufacturing or using engineered carbonaceous nanomaterials (ECNs). Methods: Information was collected through phone surveys on work practices and exposure control strategies from 30 participating producers and users of ECN. The participants were classified into three groups for further examination. Results: We report here the use of exposure control strategies. Observed patterns suggest that large-scale manufacturers report greater use of nanospecific exposure control strategies particularly for respiratory protection. Conclusion: Workplaces producing or using ECN generally report using engineering and administrative controls as well as personal protective equipment to control workplace employee exposure. JF - Journal of Occupational and Environmental Medicine AU - Dahm, M M AU - Yencken AU - Schubauer-Berigan, M K AD - National Institute for Occupational Safety and Health, Division of Surveillance, Hazard Evaluations, and Field Studies, Industrywide Studies Branch, 4676 Columbia Parkway, MS-R14, Cincinnati, OH 45226, USA, mdahm@cdc.gov Y1 - 2011/06// PY - 2011 DA - Jun 2011 SP - S68 EP - S73 VL - 53 SN - 1076-2752, 1076-2752 KW - Health & Safety Science Abstracts KW - Nanotechnology KW - Occupational exposure KW - Protective equipment KW - USA KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1020840497?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Exposure+Control+Strategies+in+the+Carbonaceous+Nanomaterial+Industry&rft.au=Dahm%2C+M+M%3BYencken%3BSchubauer-Berigan%2C+M+K&rft.aulast=Dahm&rft.aufirst=M&rft.date=2011-06-01&rft.volume=53&rft.issue=&rft.spage=S68&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e31821b1d3b LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-06-01 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - Protective equipment; Occupational exposure; Nanotechnology; USA DO - http://dx.doi.org/10.1097/JOM.0b013e31821b1d3b ER - TY - JOUR T1 - Identification of Systemic Markers from A Pulmonary Carbon Nanotube Exposure AN - 1020837748; 15112473 AB - Objective: Interest exists for early monitoring of worker exposure to engineered nanomaterials. Here, we highlight quantitative systemic markers of early effects after carbon nanotube (CNT) exposure. Methods: Mice were exposed by pharyngeal aspiration to 40- mu g CNT and harvested 24 hours, 7 days, and 28 days postexposure for measurements of whole blood, lung and extrapulmonary tissue gene expression, blood and bronchoalveolar lavage (BAL) differentials, and serum protein profiling. Results: Early effects included increased inflammatory blood gene expression and serum cytokines followed by an acute phase response (eg, CRP, SAA-1, SAP). Beyond 24 hours, there was a consistent increase in blood and BAL eosinophils. At 28 day, serum acute phase proteins with immune function including complement C3, apolipoproteins A-I and A-II, and alpha sub(2)-macroglobulin were increased. Conclusions: Carbon nanotube exposure resulted in measurable systemic markers but lacked specificity to distinguish from other pulmonary exposures. JF - Journal of Occupational and Environmental Medicine AU - Erdely, A AU - Liston, A AU - Salmen-Muniz, R AU - Hulderman, T AU - Young, S-H AU - Zeidler-Erdely, P C AU - Castranova, V AU - Simeonova, P P AD - NIOSH/HELD/TMBB, 1095 Willowdale Rd, MS-3014, Morgantown, WV 26505, USA, efi4@cdc.gov Y1 - 2011/06// PY - 2011 DA - Jun 2011 SP - S80 EP - S86 VL - 53 SN - 1076-2752, 1076-2752 KW - Health & Safety Science Abstracts KW - Immune response KW - Lung KW - Mice KW - Occupational exposure KW - Proteins KW - nanotechnology KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1020837748?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Identification+of+Systemic+Markers+from+A+Pulmonary+Carbon+Nanotube+Exposure&rft.au=Erdely%2C+A%3BListon%2C+A%3BSalmen-Muniz%2C+R%3BHulderman%2C+T%3BYoung%2C+S-H%3BZeidler-Erdely%2C+P+C%3BCastranova%2C+V%3BSimeonova%2C+P+P&rft.aulast=Erdely&rft.aufirst=A&rft.date=2011-06-01&rft.volume=53&rft.issue=&rft.spage=S80&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e31821ad724 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-06-01 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - Lung; Proteins; Mice; Immune response; Occupational exposure; nanotechnology DO - http://dx.doi.org/10.1097/JOM.0b013e31821ad724 ER - TY - JOUR T1 - Does the small farm exemption cost lives? AN - 1017966886; 16691552 AB - Background Congress has exempted farms with fewer than 11 employees from enforcement of the Occupational Safety and Health Act. Three states (California, Oregon, and Washington) do not observe the exemption. Methods We compared rates of fatal occupational injury in agriculture, by year, in 1993-2007, in California, Oregon, and Washington (aggregated), and the remaining states (as two aggregated groups): those with, and those without, state-designed occupational safety and health programs. Results Fatality rates were approximately 1.6 to 3 times as high in both groups of states observing the small farm exemption as in the group of three states not observing it. Comparisons excluding the agriculture industry showed weaker differences. Conclusions The three states' opting out of the small farm exemption may have had substantial direct effects. They may also reflect and/or encourage a generally more effective approach to occupational health and safety. Although alternative explanations must be considered, the stakes are high in terms of injury and loss of life; further investigation seems urgently indicated. Am. J. Ind. Med. 54:461-466, 2011. ? 2011 Wiley-Liss, Inc. JF - American Journal of Industrial Medicine AU - Somervell, Philip D AU - Conway, George A AD - Epidemiologist Alaska Pacific Regional Office, National Institute for Occupational Safety and Health, Anchorage, Alaska, gjx7@cdc.gov Y1 - 2011/06// PY - 2011 DA - Jun 2011 SP - 461 EP - 466 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 54 IS - 6 SN - 1097-0274, 1097-0274 KW - Health & Safety Science Abstracts KW - USA, Washington KW - Mortality KW - Injuries KW - farms KW - Congress KW - Occupational safety KW - agriculture KW - USA, California KW - small farms KW - Occupational health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1017966886?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Does+the+small+farm+exemption+cost+lives%3F&rft.au=Somervell%2C+Philip+D%3BConway%2C+George+A&rft.aulast=Somervell&rft.aufirst=Philip&rft.date=2011-06-01&rft.volume=54&rft.issue=6&rft.spage=461&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=10970274&rft_id=info:doi/10.1002%2Fajim.20931 L2 - http://onlinelibrary.wiley.com/doi/10.1002/ajim.20931/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2013-06-28 N1 - SubjectsTermNotLitGenreText - Mortality; Injuries; Congress; farms; Occupational safety; agriculture; small farms; Occupational health; USA, Washington; USA, California DO - http://dx.doi.org/10.1002/ajim.20931 ER - TY - CPAPER T1 - Solving the Problems of Pertussis PCR Diagnostics T2 - 111th General Meeting of the American Society for Microbiology (ASM 2011) AN - 866052948; 9956898; 6039348 JF - 111th General Meeting of the American Society for Microbiology (ASM 2011) AU - Tatti, K Y1 - 2011/05/21/ PY - 2011 DA - 2011 May 21 KW - Polymerase chain reaction KW - Pertussis KW - Nucleotide sequence UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/866052948?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=111th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2011%29&rft.atitle=Solving+the+Problems+of+Pertussis+PCR+Diagnostics&rft.au=Tatti%2C+K&rft.aulast=Tatti&rft.aufirst=K&rft.date=2011-05-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=111th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/Browse.aspx LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-30 N1 - Last updated - 2012-09-05 ER - TY - CPAPER T1 - Characterization of Salmonella enterica serotype Newport Associated with Foodborne Illness Using Multiple-Locus Variable-Number Tandem Repeat Analysis T2 - 111th General Meeting of the American Society for Microbiology (ASM 2011) AN - 1313050099; 6036586 JF - 111th General Meeting of the American Society for Microbiology (ASM 2011) AU - Sabol, A AU - Lafon, P AU - Ribot, E AU - Hyytia-Trees, E Y1 - 2011/05/21/ PY - 2011 DA - 2011 May 21 KW - food-borne diseases KW - Serotypes KW - Food KW - Anadromous species KW - Salmonella enterica UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313050099?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=111th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2011%29&rft.atitle=Characterization+of+Salmonella+enterica+serotype+Newport+Associated+with+Foodborne+Illness+Using+Multiple-Locus+Variable-Number+Tandem+Repeat+Analysis&rft.au=Sabol%2C+A%3BLafon%2C+P%3BRibot%2C+E%3BHyytia-Trees%2C+E&rft.aulast=Sabol&rft.aufirst=A&rft.date=2011-05-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=111th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/Browse.aspx LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Detection of Clostridium perfringens in Foodborne Investigations T2 - 111th General Meeting of the American Society for Microbiology (ASM 2011) AN - 1313017398; 6038801 JF - 111th General Meeting of the American Society for Microbiology (ASM 2011) AU - Gomez, G AU - Dykes, J AU - Luquez, C AU - Talkington, D Y1 - 2011/05/21/ PY - 2011 DA - 2011 May 21 KW - Food KW - Clostridium perfringens UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313017398?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=111th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2011%29&rft.atitle=Detection+of+Clostridium+perfringens+in+Foodborne+Investigations&rft.au=Gomez%2C+G%3BDykes%2C+J%3BLuquez%2C+C%3BTalkington%2C+D&rft.aulast=Gomez&rft.aufirst=G&rft.date=2011-05-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=111th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/Browse.aspx LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Detection of a Novel Spotted Fever Group Rickettsia in the Gopher Tortoise Tick - Amblyomma tuberculatum in Georgia, USA T2 - 111th General Meeting of the American Society for Microbiology (ASM 2011) AN - 1312967760; 6037083 JF - 111th General Meeting of the American Society for Microbiology (ASM 2011) AU - Zemtsova, G AU - Lydy, S AU - Levin, M AU - Gleim, E AU - Yabsley, M Y1 - 2011/05/21/ PY - 2011 DA - 2011 May 21 KW - USA, Georgia KW - tortoises KW - Spotted fevers KW - Amblyomma KW - Ixodidae KW - Rickettsia UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312967760?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=111th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2011%29&rft.atitle=Detection+of+a+Novel+Spotted+Fever+Group+Rickettsia+in+the+Gopher+Tortoise+Tick+-+Amblyomma+tuberculatum+in+Georgia%2C+USA&rft.au=Zemtsova%2C+G%3BLydy%2C+S%3BLevin%2C+M%3BGleim%2C+E%3BYabsley%2C+M&rft.aulast=Zemtsova&rft.aufirst=G&rft.date=2011-05-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=111th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/Browse.aspx LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Developing Indigenous Epidemiologic and Laboratory Capacity in Sub-Saharan Africa T2 - 111th General Meeting of the American Society for Microbiology (ASM 2011) AN - 1312931977; 6038914 JF - 111th General Meeting of the American Society for Microbiology (ASM 2011) AU - Oundo, Joseph Y1 - 2011/05/21/ PY - 2011 DA - 2011 May 21 KW - Africa KW - Public health KW - Epidemiology KW - Microbiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312931977?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=111th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2011%29&rft.atitle=Developing+Indigenous+Epidemiologic+and+Laboratory+Capacity+in+Sub-Saharan+Africa&rft.au=Oundo%2C+Joseph&rft.aulast=Oundo&rft.aufirst=Joseph&rft.date=2011-05-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=111th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/Browse.aspx LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Impact of H1N1 on Rapid Influenza Diagnostic Testing (RIDT) Practices in Outpatient Medical Settings T2 - 111th General Meeting of the American Society for Microbiology (ASM 2011) AN - 1312931846; 6039001 JF - 111th General Meeting of the American Society for Microbiology (ASM 2011) AU - Williams, L AU - Barrett, S AU - Kupka, N AU - Robinson, P AU - Schmaltz, S AU - Zehnbauer, B Y1 - 2011/05/21/ PY - 2011 DA - 2011 May 21 KW - influenza KW - Influenza UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312931846?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=111th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2011%29&rft.atitle=Impact+of+H1N1+on+Rapid+Influenza+Diagnostic+Testing+%28RIDT%29+Practices+in+Outpatient+Medical+Settings&rft.au=Williams%2C+L%3BBarrett%2C+S%3BKupka%2C+N%3BRobinson%2C+P%3BSchmaltz%2C+S%3BZehnbauer%2C+B&rft.aulast=Williams&rft.aufirst=L&rft.date=2011-05-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=111th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/Browse.aspx LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - The Burden of Noroviruses in Healthcare Settings and the Role of High Touch Surfaces in Transmission T2 - 111th General Meeting of the American Society for Microbiology (ASM 2011) AN - 1312915003; 6038354 JF - 111th General Meeting of the American Society for Microbiology (ASM 2011) AU - Lopman, Ben Y1 - 2011/05/21/ PY - 2011 DA - 2011 May 21 KW - Health care KW - Tactile stimuli KW - Norovirus UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312915003?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=111th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2011%29&rft.atitle=The+Burden+of+Noroviruses+in+Healthcare+Settings+and+the+Role+of+High+Touch+Surfaces+in+Transmission&rft.au=Lopman%2C+Ben&rft.aulast=Lopman&rft.aufirst=Ben&rft.date=2011-05-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=111th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/Browse.aspx LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Development of a Novel Genus-specific Real-time PCR Assay for Detection and Speciation of Bartonella T2 - 111th General Meeting of the American Society for Microbiology (ASM 2011) AN - 1312899196; 6037432 JF - 111th General Meeting of the American Society for Microbiology (ASM 2011) AU - Diaz, M AU - Bai, Y AU - Winchell, J AU - Kosoy, M AU - Malania, L Y1 - 2011/05/21/ PY - 2011 DA - 2011 May 21 KW - Speciation KW - Polymerase chain reaction KW - Nucleotide sequence KW - Bartonella UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312899196?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=111th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2011%29&rft.atitle=Development+of+a+Novel+Genus-specific+Real-time+PCR+Assay+for+Detection+and+Speciation+of+Bartonella&rft.au=Diaz%2C+M%3BBai%2C+Y%3BWinchell%2C+J%3BKosoy%2C+M%3BMalania%2C+L&rft.aulast=Diaz&rft.aufirst=M&rft.date=2011-05-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=111th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/Browse.aspx LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Sequence Based Types of Sporadic, Outbreak-Associated, and Environmental Legionella pneumophila Serogroup 1 Isolates Deposited to the CDC Reference Collection 1982-2010 T2 - 111th General Meeting of the American Society for Microbiology (ASM 2011) AN - 1312898616; 6037425 JF - 111th General Meeting of the American Society for Microbiology (ASM 2011) AU - Kozak, N AU - Lucas, C AU - Pondo, T AU - Brown, E AU - Frace, M AU - Olsen-Rasmussen, M AU - Yang, G AU - Garrison, L AU - Hicks, L AU - Fields, B AU - Miskowski, D Y1 - 2011/05/21/ PY - 2011 DA - 2011 May 21 KW - outbreaks KW - Legionella pneumophila UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312898616?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=111th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2011%29&rft.atitle=Sequence+Based+Types+of+Sporadic%2C+Outbreak-Associated%2C+and+Environmental+Legionella+pneumophila+Serogroup+1+Isolates+Deposited+to+the+CDC+Reference+Collection+1982-2010&rft.au=Kozak%2C+N%3BLucas%2C+C%3BPondo%2C+T%3BBrown%2C+E%3BFrace%2C+M%3BOlsen-Rasmussen%2C+M%3BYang%2C+G%3BGarrison%2C+L%3BHicks%2C+L%3BFields%2C+B%3BMiskowski%2C+D&rft.aulast=Kozak&rft.aufirst=N&rft.date=2011-05-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=111th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/Browse.aspx LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Validation of a Broth Screen for the Detection of Metallo-beta-Lactamases T2 - 111th General Meeting of the American Society for Microbiology (ASM 2011) AN - 1312896465; 6036817 JF - 111th General Meeting of the American Society for Microbiology (ASM 2011) AU - Anderson, K AU - Rasheed, J AU - Kitchel, B AU - Wong, B AU - Clark, N AU - Limbago, B Y1 - 2011/05/21/ PY - 2011 DA - 2011 May 21 KW - Public health KW - Epidemiology KW - Microbiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312896465?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=111th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2011%29&rft.atitle=Validation+of+a+Broth+Screen+for+the+Detection+of+Metallo-beta-Lactamases&rft.au=Anderson%2C+K%3BRasheed%2C+J%3BKitchel%2C+B%3BWong%2C+B%3BClark%2C+N%3BLimbago%2C+B&rft.aulast=Anderson&rft.aufirst=K&rft.date=2011-05-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=111th+General+Meeting+of+the+American+Society+for+Microbiology+%28ASM+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://www.abstractsonline.com/plan/Browse.aspx LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - JOUR T1 - Laboratory Testing Practices for West Nile Virus in the United States AN - 920788159; 16154990 AB - We surveyed state public health and commercial diagnostic reference laboratories regarding current testing practices for West Nile virus (WNV). The majority of WNV testing is now performed in commercial diagnostic reference laboratories using commercially available Food and Drug Administration-cleared kits labeled for the presumptive diagnosis of WNV. However, only 25% of surveyed state public health or commercial diagnostic reference laboratories currently have the capacity to perform the recommended confirmatory testing. These findings indicate the need for both manufacturers and laboratories to monitor the performance of these WNV test kits. Further, clinicians should be aware of the limitations of these kits and the need for additional testing to confirm a diagnosis of WNV disease. JF - Vector Borne and Zoonotic Diseases AU - Janusz, K B AU - Lehman, JA AU - Panella, A J AU - Fischer, M AU - Staples, E AD - Arboviral Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, 3150 Rampart Road, Mailstop P-02, Fort Collins, CO 80521, USA, estaples@cdc.gov Y1 - 2011/05// PY - 2011 DA - May 2011 SP - 597 EP - 599 VL - 11 IS - 5 SN - 1530-3667, 1530-3667 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Virology & AIDS Abstracts KW - USA KW - Vectors KW - Hosts KW - Drugs KW - West Nile virus KW - Disease transmission KW - Public health KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/920788159?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vector+Borne+and+Zoonotic+Diseases&rft.atitle=Laboratory+Testing+Practices+for+West+Nile+Virus+in+the+United+States&rft.au=Janusz%2C+K+B%3BLehman%2C+JA%3BPanella%2C+A+J%3BFischer%2C+M%3BStaples%2C+E&rft.aulast=Janusz&rft.aufirst=K&rft.date=2011-05-01&rft.volume=11&rft.issue=5&rft.spage=597&rft.isbn=&rft.btitle=&rft.title=Vector+Borne+and+Zoonotic+Diseases&rft.issn=15303667&rft_id=info:doi/10.1089%2Fvbz.2010.0058 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-02-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Hosts; Drugs; Public health; Disease transmission; Vectors; West Nile virus; USA DO - http://dx.doi.org/10.1089/vbz.2010.0058 ER - TY - JOUR T1 - The 2009 National Environmental Public Health Conference: One Model for Planning Green and Healthy Conferences AN - 908014151; 2011-146831 AB - The Centers for Disease Control and Prevention's National Center for Environmental Health and the Agency for Toxic Substances and Disease Registry committed to making their 2009 National Environmental Public Health Conference a model for green and healthy conferences. The conference included increased opportunities for physical activity, both as part of conference events and for transportation to the conference. In addition, conference meals were healthy and sustainably sourced. The conference also implemented intuitive, accessible recycling; online scheduling and evaluation to minimize hard-copy materials; and the purchase of carbon offsets to reduce the unwanted environmental impact of the conference. Public health professionals have an opportunity and obligation to support healthy behaviors at their events and to serve as leaders in this area. Facilitating healthy and sustainable choices is in alignment with goals for both public health and broader social issues -- such as environmental quality -- that have a direct bearing on public health. Adapted from the source document. JF - Public Health Reports AU - Ruckart, Perri Zeitz AU - Moore, Cory AU - Burgin, Deborah AU - Byrne, Maggie Kelly AD - Centers for Disease Control and Prevention, Agency for Toxic Substances and Disease Registry pruckart@cdc.gov Y1 - 2011/05// PY - 2011 DA - May 2011 SP - 58 EP - 63 PB - Association of Schools of Public Health, Washington DC VL - 126 IS - Supplement 1 SN - 0033-3549, 0033-3549 KW - Social conditions and policy - Associations and meetings KW - Health conditions and policy - Health and health policy KW - Health conditions and policy - Diseases and disorders KW - Environment and environmental policy - Wastes and waste management KW - Transportation and transportation policy - Transportation KW - Environment and environmental policy - Architecture and planning KW - Social conditions and policy - Social movements KW - Environmentalism KW - Transportation KW - Conferences KW - Planning KW - Environmental health KW - Diseases KW - Recycling KW - Public health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/908014151?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Public+Health+Reports&rft.atitle=The+2009+National+Environmental+Public+Health+Conference%3A+One+Model+for+Planning+Green+and+Healthy+Conferences&rft.au=Ruckart%2C+Perri+Zeitz%3BMoore%2C+Cory%3BBurgin%2C+Deborah%3BByrne%2C+Maggie+Kelly&rft.aulast=Ruckart&rft.aufirst=Perri&rft.date=2011-05-01&rft.volume=126&rft.issue=Supplement+1&rft.spage=58&rft.isbn=&rft.btitle=&rft.title=Public+Health+Reports&rft.issn=00333549&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2011-12-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Conferences; Public health; Diseases; Recycling; Transportation; Environmentalism; Planning; Environmental health ER - TY - JOUR T1 - Coal mine methane: A review of capture and utilization practices with benefits to mining safety and to greenhouse gas reduction AN - 875032995; 14694427 AB - Coal mine methane (CMM) is a term given to the methane gas produced or emitted in association with coal mining activities either from the coal seam itself or from other gassy formations underground. The amount of CMM generated at a specific operation depends on the productivity of the coal mine, the gassiness of the coal seam and any underlying and overlying formations, operational variables, and geological conditions. CMM can be captured by engineered boreholes that augment the mine's ventilation system or it can be emitted into the mine environment and exhausted from the mine shafts along with ventilation air. The large amounts of methane released during mining present concerns about adequate mine ventilation to ensure worker safety, but they also can create opportunities to generate energy if this gas is captured and utilized properly. This article reviews the technical aspects of CMM capture in and from coal mines, the main factors affecting CMM accumulations in underground coal mines, methods for capturing methane using boreholes, specific borehole designs for effective methane capture, aspects of removing methane from abandoned mines and from sealed/active gobs of operating mines, benefits of capturing and controlling CMM for mine safety, and benefits for energy production and greenhouse gas (GHG) reduction. JF - International Journal of Coal Geology AU - Karacan, COezgen AU - Ruiz, Felicia A AU - Cote, Michael AU - Phipps, Sally AD - NIOSH, Office of Mine Safety and Health Research, Pittsburgh, PA, USA, cok6@cdc.gov Y1 - 2011/05/01/ PY - 2011 DA - 2011 May 01 SP - 121 EP - 156 PB - Elsevier BV VL - 86 IS - 2-3 SN - 0166-5162, 0166-5162 KW - Pollution Abstracts KW - Coal mine methane KW - Mining safety KW - Methane drainage KW - Ventilation air methane KW - Methane utilization KW - Greenhouse gas reduction KW - Methane KW - boreholes KW - Ventilation KW - Reviews KW - Geology KW - Coal KW - Mining KW - Mines KW - Greenhouse gases KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/875032995?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Coal+Geology&rft.atitle=Coal+mine+methane%3A+A+review+of+capture+and+utilization+practices+with+benefits+to+mining+safety+and+to+greenhouse+gas+reduction&rft.au=Karacan%2C+COezgen%3BRuiz%2C+Felicia+A%3BCote%2C+Michael%3BPhipps%2C+Sally&rft.aulast=Karacan&rft.aufirst=COezgen&rft.date=2011-05-01&rft.volume=86&rft.issue=2-3&rft.spage=121&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Coal+Geology&rft.issn=01665162&rft_id=info:doi/10.1016%2Fj.coal.2011.02.009 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Methane; boreholes; Ventilation; Reviews; Geology; Mining; Coal; Greenhouse gases; Mines DO - http://dx.doi.org/10.1016/j.coal.2011.02.009 ER - TY - JOUR T1 - Factors Associated with HIV Testing History and Returning for HIV Test Results Among Men Who have Sex with Men in Thailand AN - 874196369; 14763852 AB - We evaluated factors associated with HIV testing history and returning for HIV test results among 2,049 Thai men who have sex with men. Of men, 50.3% reported prior HIV testing and 24.9% returned for HIV test results. Factors associated with prior HIV testing were male sex work, older age, employed, living away from the family, insertive anal sex role, history of drug use and having heard of effective HIV/AIDS treatment. Factors associated with returning for HIV test results were male sex work, older age, lack of a family confidant, history of sexually transmitted infections, and testing HIV negative in this study. JF - AIDS and Behavior AU - Wimonsate, Wipas AU - Naorat, Sathapana AU - Varangrat, Anchalee AU - Phanuphak, Praphan AU - Kanggarnrua, Kamolset AU - McNicholl, Janet AU - Akarasewi, Passakorn AU - Griensven, Frits AD - Thailand Ministry of Public HealthaU.S. Centers for Disease Control and Prevention Collaboration, Ministry of Public Health, 4th Floor DDC7, Nonthaburi, 11000, Thailand, wipasw@th.cdc.gov Y1 - 2011/05// PY - 2011 DA - May 2011 SP - 693 EP - 701 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 15 IS - 4 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Historical account KW - Age KW - Acquired immune deficiency syndrome KW - anal sex KW - Thailand KW - homosexuality KW - Drug abuse KW - Infection KW - prostitution KW - infectious diseases KW - Human immunodeficiency virus KW - Geriatrics KW - Drugs KW - sexually transmitted diseases KW - Sex KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/874196369?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Factors+Associated+with+HIV+Testing+History+and+Returning+for+HIV+Test+Results+Among+Men+Who+have+Sex+with+Men+in+Thailand&rft.au=Wimonsate%2C+Wipas%3BNaorat%2C+Sathapana%3BVarangrat%2C+Anchalee%3BPhanuphak%2C+Praphan%3BKanggarnrua%2C+Kamolset%3BMcNicholl%2C+Janet%3BAkarasewi%2C+Passakorn%3BGriensven%2C+Frits&rft.aulast=Wimonsate&rft.aufirst=Wipas&rft.date=2011-05-01&rft.volume=15&rft.issue=4&rft.spage=693&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-010-9755-3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-06-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Acquired immune deficiency syndrome; anal sex; Geriatrics; Infection; Drugs; Sex; infectious diseases; prostitution; Historical account; Age; Human immunodeficiency virus; homosexuality; Drug abuse; sexually transmitted diseases; Thailand DO - http://dx.doi.org/10.1007/s10461-010-9755-3 ER - TY - JOUR T1 - Provision of HIV Counseling and Testing Services at Five Community-Based Organizations Among Young Men of Color Who Have Sex with Men AN - 874192994; 14763861 AB - In the context of monitoring and improving CDC-funded HIV prevention programs, we describe HIV tests and infections, provision of results, previous HIV tests, and risk behaviors for young (aged 13a29) men of color who have sex with men who received HIV tests at five community-based organizations. Of 1,723 tests provided, 2.1% were positive and 75.7% of positives were previously unaware of their infection. The highest positivity rate was among men aged 25a29 (4.7%). Thirty-four percent of tests were provided to men who were tested for the first time. Over half the tests (53.2%) were provided to men who reported sex with a person of unknown HIV status, and 34% to men who reported sex with an anonymous partner. Continued and more focused prevention efforts are needed to reach and test young men of color who have sex with men and to identify previously undiagnosed HIV infections among this target population. JF - AIDS and Behavior AU - Stein, Renee AU - Green, Kathleen AU - Bell, Kelly AU - Toledo, Carlos A AU - Uhl, Gary AU - Moore, Andrea AU - Shelley, Gene A AU - Hardnett, Felicia P AD - Centers for Disease Control and Prevention, 1600 Clifton Rd. N.E., Mail Stop E-59, Atlanta, GA, USA, rstein1@cdc.gov Y1 - 2011/05// PY - 2011 DA - May 2011 SP - 743 EP - 750 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 15 IS - 4 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Risk Abstracts KW - Acquired immune deficiency syndrome KW - Human immunodeficiency virus KW - infection KW - prevention KW - males KW - Infection KW - community involvement KW - Sex KW - Color KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/874192994?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Provision+of+HIV+Counseling+and+Testing+Services+at+Five+Community-Based+Organizations+Among+Young+Men+of+Color+Who+Have+Sex+with+Men&rft.au=Stein%2C+Renee%3BGreen%2C+Kathleen%3BBell%2C+Kelly%3BToledo%2C+Carlos+A%3BUhl%2C+Gary%3BMoore%2C+Andrea%3BShelley%2C+Gene+A%3BHardnett%2C+Felicia+P&rft.aulast=Stein&rft.aufirst=Renee&rft.date=2011-05-01&rft.volume=15&rft.issue=4&rft.spage=743&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-010-9821-x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-06-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Infection; Color; Sex; Acquired immune deficiency syndrome; Human immunodeficiency virus; prevention; infection; males; community involvement DO - http://dx.doi.org/10.1007/s10461-010-9821-x ER - TY - JOUR T1 - Analysis of 4-aminobiphenyl in smoker's and nonsmoker's urine by tandem mass spectrometry. AN - 863423321; 21438718 AB - The aromatic amine 4-aminobiphenyl (4-ABP) is present in tobacco smoke. In humans, it is also a known bladder carcinogen. We describe here a method for the quantification of total 4-ABP in urine using capillary gas chromatography/tandem mass spectrometry, with an effective detection limit in urine samples of approximately 0.87 pg/mL. We also examined the efficiency of chemical or enzymatic hydrolysis of urinary aromatic amine metabolites. Although we found acidic or basic hydrolysis effective, we found enzymatic hydrolysis (β-glucuronidase with either Escherichia coli or Helix pomatia) ineffective. As part of this work, we also confirm the presence of N-acetyl-4-ABP and 4-ABP glucuronide in human urine samples from smokers. These metabolites have been reported in animal studies, but previously they have not been identified in human samples. These metabolites, however, were found to be unstable and thus infeasible for biomonitoring. The final validated urinary total 4-ABP assay was applied to the analysis of samples from smokers and nonsmokers, whose status was confirmed from cotinine EIA measurements. Among 41 confirmed nonsmokers, the geometric mean (95% CI) of 4-ABP concentration was 1.64 pg/mg creatinine (1.30-2.07). Conversely, in 89 smokers, the geometric mean of 4-ABP concentration was significantly greater, at 8.69 pg/mg creatinine (7.43-10.16), p < 0.001. Our results indicate that following tobacco smoke exposure, total urinary 4-ABP is a reliable biomarker for exposure to this carcinogen. JF - Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals AU - Seyler, Tiffany H AU - Bernert, John T AD - Emergency Response and Air Toxicants Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway, Atlanta, GA 30341, USA. tvh2@cdc.gov Y1 - 2011/05// PY - 2011 DA - May 2011 SP - 212 EP - 221 VL - 16 IS - 3 KW - Aminobiphenyl Compounds KW - 0 KW - Biomarkers KW - 4-biphenylamine KW - 16054949HJ KW - Index Medicus KW - Young Adult KW - Humans KW - Adult KW - Biomarkers -- urine KW - Middle Aged KW - Tandem Mass Spectrometry KW - Male KW - Female KW - Aminobiphenyl Compounds -- urine KW - Smoking -- urine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/863423321?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biomarkers+%3A+biochemical+indicators+of+exposure%2C+response%2C+and+susceptibility+to+chemicals&rft.atitle=Analysis+of+4-aminobiphenyl+in+smoker%27s+and+nonsmoker%27s+urine+by+tandem+mass+spectrometry.&rft.au=Seyler%2C+Tiffany+H%3BBernert%2C+John+T&rft.aulast=Seyler&rft.aufirst=Tiffany&rft.date=2011-05-01&rft.volume=16&rft.issue=3&rft.spage=212&rft.isbn=&rft.btitle=&rft.title=Biomarkers+%3A+biochemical+indicators+of+exposure%2C+response%2C+and+susceptibility+to+chemicals&rft.issn=1366-5804&rft_id=info:doi/10.3109%2F1354750X.2010.544755 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-08-08 N1 - Date created - 2011-04-21 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.3109/1354750X.2010.544755 ER - TY - JOUR T1 - Global surveillance of oral tobacco products: total nicotine, unionised nicotine and tobacco-specific N-nitrosamines. AN - 862793180; 21109685 AB - Oral tobacco products contain nicotine and carcinogenic tobacco-specific N-nitrosamines (TSNAs) that can be absorbed through the oral mucosa. The aim of this study was to determine typical pH ranges and concentrations of total nicotine, unionised nicotine (the most readily absorbed form) and five TSNAs in selected oral tobacco products distributed globally. A total of 53 oral tobacco products from 5 World Health Organisation (WHO) regions were analysed for total nicotine and TSNAs, including 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), using gas chromatography or liquid chromatography with mass spectrometric detection. Unionised nicotine concentrations were calculated using product pH and total nicotine concentrations. Fourier transform infrared spectroscopy was used to help categorize or characterise some products. Total nicotine content varied from 0.16 to 34.1 mg/g product, whereas, the calculated unionised nicotine ranged from 0.05 to 31.0 mg/g product; a 620-fold range of variation. Products ranged from pH 5.2 to 10.1, which translates to 0.2% to 99.1% of nicotine being in the unionised form. Some products have very high pH and correspondingly high unionised nicotine (eg, gul powder, chimó, toombak) and/or high TSNA (eg, toombak, zarda, khaini) concentrations. The concentrations of TSNAs spanned five orders of magnitude with concentrations of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ranging from 4.5 to 516,000 ng/g product. These data have important implications for risk assessment because they show that very different exposure risks may be posed through the use of these chemically diverse oral tobacco products. Because of the wide chemical variation, oral tobacco products should not be categorised together when considering the public health implications of their use. JF - Tobacco control AU - Stanfill, Stephen B AU - Connolly, Gregory N AU - Zhang, Liqin AU - Jia, Lily T AU - Henningfield, Jack E AU - Richter, Patricia AU - Lawler, Tameka S AU - Ayo-Yusuf, Olalekan A AU - Ashley, David L AU - Watson, Clifford H AD - Centers for Disease Control and Prevention, National Center for Environmental Health, Division of Laboratory Sciences, Emergency Response and Air Toxicants Branch, 4770 Buford Highway, Atlanta, Georgia 30341, USA. sstanfill@cdc.gov Y1 - 2011/05// PY - 2011 DA - May 2011 SP - 1 VL - 20 IS - 3 KW - Carcinogens KW - 0 KW - Nitrosamines KW - Nicotine KW - 6M3C89ZY6R KW - Index Medicus KW - Global Health KW - Spectroscopy, Fourier Transform Infrared KW - Hydrogen-Ion Concentration KW - Humans KW - Nicotine -- analysis KW - Carcinogens -- analysis KW - Tobacco, Smokeless -- chemistry KW - Nitrosamines -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/862793180?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Tobacco+control&rft.atitle=Global+surveillance+of+oral+tobacco+products%3A+total+nicotine%2C+unionised+nicotine+and+tobacco-specific+N-nitrosamines.&rft.au=Stanfill%2C+Stephen+B%3BConnolly%2C+Gregory+N%3BZhang%2C+Liqin%3BJia%2C+Lily+T%3BHenningfield%2C+Jack+E%3BRichter%2C+Patricia%3BLawler%2C+Tameka+S%3BAyo-Yusuf%2C+Olalekan+A%3BAshley%2C+David+L%3BWatson%2C+Clifford+H&rft.aulast=Stanfill&rft.aufirst=Stephen&rft.date=2011-05-01&rft.volume=20&rft.issue=3&rft.spage=e2&rft.isbn=&rft.btitle=&rft.title=Tobacco+control&rft.issn=1468-3318&rft_id=info:doi/10.1136%2Ftc.2010.037465 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-11-08 N1 - Date created - 2011-04-19 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1136/tc.2010.037465 ER - TY - JOUR T1 - Discrimination of haptens from prohaptens using the metabolically deficient Cpr(low/low) mouse. AN - 862792978; 21376747 AB - The murine local lymph node assay (LLNA) is a validated, well accepted method for identification of chemical contact allergens. Both direct acting haptens and prohaptens (requiring metabolic activation) can be identified, but not differentiated by this assay. This study was used to assess the utility of a pan microsomal metabolic deficient mouse to distinguish between direct acting haptens and prohaptens in the LLNA. Hapten and prohapten induced cell proliferation was compared in C57BL/6J (B6) wild type (WT) versus homozygous (HO) knockout mice with a hypomorphic NADPH-Cytochrome P450 Reductase (CPR) gene (termed Cpr(low/low)) resulting in low CPR enzyme activity. Mice were dosed with known prohaptens; benzo(a)pyrene (BaP), carvone oxime (COx) and paracetamol (PCM) and haptens; oxazolone (OX), 4-ethoxymethylene-2-phenyl-2-oxazolin-5-one (EtOX), and N-acetylbenzoquinoneimine (NABQI) in this study. Skin microsomes from the WT, HO and heterozygous (HT) Cpr(low/low) mice were compared and evaluated for CPR activity. Lymphocyte proliferative responses to BaP, COx and PCM were significantly abrogated by 36.4%, 45.2% and 50.8%, respectively; in Cpr(low/low) knock out (KO) mice versus WT mice; while the lymphocyte proliferative responses to the direct acting haptens OX, EtOX and NABQI were comparable. CPR activity, determined as Units/mg protein, was determined to be significantly lower in the Cpr(low/low) mice compared to the WT. Results of the present study suggest potential utility of the Cpr(low/low) mice in the LLNA to differentiate prohaptens from direct acting haptens. Published by Elsevier Inc. JF - Toxicology and applied pharmacology AU - Chipinda, Itai AU - Blachere, Francoise M AU - Anderson, Stacey E AU - Siegel, Paul D AD - Allergy and Clinical Immunology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown,WV 26505-2888, USA. IChipinda@cdc.gov Y1 - 2011/05/01/ PY - 2011 DA - 2011 May 01 SP - 268 EP - 272 VL - 252 IS - 3 KW - Allergens KW - 0 KW - Haptens KW - NADPH-Ferrihemoprotein Reductase KW - EC 1.6.2.4 KW - Index Medicus KW - Animals KW - In Vitro Techniques KW - Mice, Inbred C57BL KW - Mice KW - Local Lymph Node Assay KW - Male KW - Female KW - Mice, Knockout KW - NADPH-Ferrihemoprotein Reductase -- genetics KW - Skin -- drug effects KW - Haptens -- metabolism KW - Skin -- metabolism KW - Allergens -- metabolism KW - Haptens -- pharmacology KW - NADPH-Ferrihemoprotein Reductase -- metabolism KW - NADPH-Ferrihemoprotein Reductase -- deficiency KW - Allergens -- pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/862792978?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+applied+pharmacology&rft.atitle=Discrimination+of+haptens+from+prohaptens+using+the+metabolically+deficient+Cpr%28low%2Flow%29+mouse.&rft.au=Chipinda%2C+Itai%3BBlachere%2C+Francoise+M%3BAnderson%2C+Stacey+E%3BSiegel%2C+Paul+D&rft.aulast=Chipinda&rft.aufirst=Itai&rft.date=2011-05-01&rft.volume=252&rft.issue=3&rft.spage=268&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+applied+pharmacology&rft.issn=1096-0333&rft_id=info:doi/10.1016%2Fj.taap.2011.02.018 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-07-11 N1 - Date created - 2011-04-19 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.taap.2011.02.018 ER - TY - JOUR T1 - Cohort mortality study of workers at seven beryllium processing plants: update and associations with cumulative and maximum exposure. AN - 861203354; 20952555 AB - To extend follow-up of cause-specific mortality in workers at seven beryllium processing plants and to estimate associations between mortality risk and beryllium exposure. 9199 workers were followed for mortality from 1940 through 2005. Standardised mortality ratios (SMRs) were estimated based on US population comparisons for lung, nervous system and urinary tract cancers, chronic obstructive pulmonary disease (COPD), chronic kidney disease, and categories containing chronic beryllium disease (CBD) and cor pulmonale. Associations with maximum and cumulative exposure were calculated for a subset of the workers. Overall mortality in the cohort compared with the US population was elevated for lung cancer (SMR 1.17; 95% CI 1.08 to 1.28), COPD (SMR 1.23; 95% CI 1.13 to 1.32), and the categories containing CBD (SMR 7.80; 95% CI 6.26 to 9.60) and cor pulmonale (SMR 1.17; 95% CI 1.08 to 1.26). Mortality rates for most diseases of interest increased with time-since-hire. For the category including CBD, rates were substantially elevated compared to the US population across all exposure groups. Workers whose maximum beryllium exposure was ≥ 10 μg/m(3) had higher rates of lung cancer, urinary tract cancer, COPD and the category containing cor pulmonale than workers with lower exposure. Significant positive trends with cumulative exposure were observed for nervous system cancers (p = 0.0006) and, when short-term workers were excluded, lung cancer (p = 0.01), urinary tract cancer (p = 0.003) and COPD (p < 0.0001). These findings reaffirm that lung cancer and CBD, and suggest that COPD and nervous system and urinary tract cancers, are related to beryllium exposure. Cigarette smoking and exposure to other lung carcinogens are unlikely to explain these elevations. JF - Occupational and environmental medicine AU - Schubauer-Berigan, Mary K AU - Couch, James R AU - Petersen, Martin R AU - Carreón, Tania AU - Jin, Yan AU - Deddens, James A AD - Division of Surveillance, Hazard Evaluations, and Field Studies, National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA. zcg3@cdc.gov Y1 - 2011/05// PY - 2011 DA - May 2011 SP - 345 EP - 353 VL - 68 IS - 5 KW - Beryllium KW - OW5102UV6N KW - Index Medicus KW - Nervous System Neoplasms -- mortality KW - Dose-Response Relationship, Drug KW - Epidemiologic Methods KW - Humans KW - Smoking -- adverse effects KW - Aged KW - Urologic Neoplasms -- mortality KW - Berylliosis -- mortality KW - Urologic Neoplasms -- chemically induced KW - Aged, 80 and over KW - Adult KW - Occupational Exposure -- adverse effects KW - Pulmonary Disease, Chronic Obstructive -- chemically induced KW - Nervous System Neoplasms -- chemically induced KW - Middle Aged KW - Epidemiological Monitoring KW - Lung Neoplasms -- mortality KW - Lung Neoplasms -- chemically induced KW - United States -- epidemiology KW - Time Factors KW - Occupational Exposure -- analysis KW - Environmental Monitoring -- methods KW - Male KW - Pulmonary Disease, Chronic Obstructive -- mortality KW - Occupational Diseases -- chemically induced KW - Occupational Diseases -- mortality KW - Beryllium -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/861203354?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Occupational+and+environmental+medicine&rft.atitle=Cohort+mortality+study+of+workers+at+seven+beryllium+processing+plants%3A+update+and+associations+with+cumulative+and+maximum+exposure.&rft.au=Schubauer-Berigan%2C+Mary+K%3BCouch%2C+James+R%3BPetersen%2C+Martin+R%3BCarre%C3%B3n%2C+Tania%3BJin%2C+Yan%3BDeddens%2C+James+A&rft.aulast=Schubauer-Berigan&rft.aufirst=Mary&rft.date=2011-05-01&rft.volume=68&rft.issue=5&rft.spage=345&rft.isbn=&rft.btitle=&rft.title=Occupational+and+environmental+medicine&rft.issn=1470-7926&rft_id=info:doi/10.1136%2Foem.2010.056481 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-07-18 N1 - Date created - 2011-04-08 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Comment In: Occup Environ Med. 2012 Aug;69(8):607 [22383592] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1136/oem.2010.056481 ER - TY - JOUR T1 - Risk of lung cancer associated with quantitative beryllium exposure metrics within an occupational cohort. AN - 861202965; 21084327 AB - Beryllium has been identified as a human carcinogen on the basis of animal and epidemiological studies. The authors recently reported updated associations between lung cancer and beryllium exposure in a large, pooled occupational cohort. The authors conducted the present study to evaluate the shape of exposure-response associations between different exposure metrics and lung cancer in this cohort, considering potential confounders (race, plant, professional and short-term work status, and exposure to other lung carcinogens). The authors conducted Cox proportional hazards regression analyses of lung cancer risk with cumulative, mean and maximum 'daily weighted average' (DWA) exposure among 5436 workers, using age-based risk sets. Different exposure-response curves were fitted to the exposure metrics, including categorical, power, restricted cubic spline and piecewise log-linear fits. The authors found significant positive associations between lung cancer and mean (p < 0.0001) and maximum (p < 0.0001) exposure, adjusting for age, birth cohort and plant, and for cumulative (p = 0.0017) beryllium exposure, adjusting for these factors plus short-term work status and exposure to asbestos. The best-fitting models were generally categorical or piecewise log-linear, with the steepest increase in lung cancer risk between 0 and 10 μg/m(3) for both mean and maximum DWA exposure and between 0 and 200 μg/m(3)-days for cumulative DWA exposure. The estimated mean DWA beryllium exposure associated with 10(-3) excess lifetime risk based on the piecewise log-linear model is 0.033 μg/m(3). This study provides evidence that lung cancer risk is elevated at levels near the current US Occupational Safety and Health Administration beryllium exposure limit of 2.0 μg/m(3) DWA for workers. JF - Occupational and environmental medicine AU - Schubauer-Berigan, Mary K AU - Deddens, James A AU - Couch, James R AU - Petersen, Martin R AD - National Institute for Occupational Safety and Health, Division of Surveillance, Hazard Evaluations, and Field Studies, Cincinnati, Ohio 45226, USA. zcg3@cdc.gov Y1 - 2011/05// PY - 2011 DA - May 2011 SP - 354 EP - 360 VL - 68 IS - 5 KW - Carcinogens KW - 0 KW - Beryllium KW - OW5102UV6N KW - Index Medicus KW - Epidemiologic Methods KW - Dose-Response Relationship, Drug KW - Humans KW - Occupational Exposure -- adverse effects KW - Epidemiological Monitoring KW - United States -- epidemiology KW - Occupational Exposure -- analysis KW - Male KW - Environmental Monitoring -- methods KW - Lung Neoplasms -- epidemiology KW - Carcinogens -- toxicity KW - Occupational Diseases -- epidemiology KW - Lung Neoplasms -- chemically induced KW - Occupational Diseases -- chemically induced KW - Beryllium -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/861202965?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Occupational+and+environmental+medicine&rft.atitle=Risk+of+lung+cancer+associated+with+quantitative+beryllium+exposure+metrics+within+an+occupational+cohort.&rft.au=Schubauer-Berigan%2C+Mary+K%3BDeddens%2C+James+A%3BCouch%2C+James+R%3BPetersen%2C+Martin+R&rft.aulast=Schubauer-Berigan&rft.aufirst=Mary&rft.date=2011-05-01&rft.volume=68&rft.issue=5&rft.spage=354&rft.isbn=&rft.btitle=&rft.title=Occupational+and+environmental+medicine&rft.issn=1470-7926&rft_id=info:doi/10.1136%2Foem.2010.056515 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-07-18 N1 - Date created - 2011-04-08 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1136/oem.2010.056515 ER - TY - JOUR T1 - Metabolic Syndrome and Carotid Intima Media Thickness in Urban Police Officers AN - 1020843996; 14930902 AB - Objective: To examine the association between metabolic syndrome (MetSyn) and carotid intima media thickness (IMT) separately in male and female police officers. Methods: MetSyn was defined using 2005 guidelines. B-mode ultrasound was used to measure mean and maximum (12 and 36 segments) carotid artery thickness. Analysis of covariance was used to compare mean IMT values across individuals categorized by number of MetSyn components. Adjustments were made for age, smoking status, and low-density lipoprotein cholesterol. Results: Among 106 women, the adjusted mean common and maximum36 carotid IMT were significantly and positively associated with number of MetSyn components. No associations were found in men (n = 304). Adjusted carotid IMT values were inversely associated with low high-density lipoprotein cholesterol and directly with hypertension in women. Conclusions: Number of MetSyn components was significantly associated with carotid IMT in female but not in male officers. JF - Journal of Occupational and Environmental Medicine AU - Hartley, T A AU - Shankar, A AU - Fekedulegn, D AU - Violanti, J M AU - Andrew, ME AU - Knox, S S AU - Burchfiel, C M AD - Biostatistics and Epidemiology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, 1095 Willowdale Road, MS 4050, Morgantown, WV 26505, USA, thartley@cdc.gov Y1 - 2011/05// PY - 2011 DA - May 2011 SP - 553 EP - 561 VL - 53 IS - 5 SN - 1076-2752, 1076-2752 KW - Health & Safety Science Abstracts KW - Age KW - Guidelines KW - Hypertension KW - Smoking KW - cholesterol KW - metabolic disorders KW - police KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1020843996?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Metabolic+Syndrome+and+Carotid+Intima+Media+Thickness+in+Urban+Police+Officers&rft.au=Hartley%2C+T+A%3BShankar%2C+A%3BFekedulegn%2C+D%3BViolanti%2C+J+M%3BAndrew%2C+ME%3BKnox%2C+S+S%3BBurchfiel%2C+C+M&rft.aulast=Hartley&rft.aufirst=T&rft.date=2011-05-01&rft.volume=53&rft.issue=5&rft.spage=553&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e3182171995 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-06-01 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - Smoking; Age; metabolic disorders; police; Guidelines; cholesterol; Hypertension DO - http://dx.doi.org/10.1097/JOM.0b013e3182171995 ER - TY - JOUR T1 - Does social media improve communication? Evaluating the NIOSH science blog AN - 1017966967; 16691562 AB - Background In 2007, NIOSH created the Science Blog as its first social media channel. The blog has more than 22,000 subscribers. The purpose of the evaluation was to identify the blog community of readers, its use as a two-way conversation channel and its effectiveness as an information resource. Methods Seventy-five readers randomly participated in an online survey from July 2009 to September 2009 to evaluate the Science Blog. Results Responses indicated that the NIOSH Science Blog was a valued social media resource. Sixty percent of participants planned to continue using the blog in the next 6 months. A significant proportion of readers reported that they would make changes in the workplace based on information obtained from the Science Blog. Conclusions The NIOSH Science Blog provides is a useful communication channel to provide workplace safety and health information and expand the Institute's reach to new consumers. Am. J. Ind. Med. 54:384-394, 2011. ? 2011 Wiley-Liss, Inc. JF - American Journal of Industrial Medicine AU - Sublet, Virginia AU - Spring, Christina AU - Howard, John AD - Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Atlanta, Georgia, vxs3@cdc.gov Y1 - 2011/05// PY - 2011 DA - May 2011 SP - 384 EP - 394 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 54 IS - 5 SN - 1097-0274, 1097-0274 KW - Health & Safety Science Abstracts KW - Communications KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1017966967?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Does+social+media+improve+communication%3F+Evaluating+the+NIOSH+science+blog&rft.au=Sublet%2C+Virginia%3BSpring%2C+Christina%3BHoward%2C+John&rft.aulast=Sublet&rft.aufirst=Virginia&rft.date=2011-05-01&rft.volume=54&rft.issue=5&rft.spage=384&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=10970274&rft_id=info:doi/10.1002%2Fajim.20921 L2 - http://onlinelibrary.wiley.com/doi/10.1002/ajim.20921/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2015-08-05 N1 - SubjectsTermNotLitGenreText - Communications DO - http://dx.doi.org/10.1002/ajim.20921 ER - TY - JOUR T1 - US Adolescent Nutrition, Exercise, and Screen Time Baseline Levels Prior to National Recommendations AN - 1011204752; 14875561 AB - Experts have recommended daily obesity prevention goals: greater than or equal to 5 fruits/vegetables, 1 hour of physical activity, and no sugar-sweetened beverages (5-2-1-0). The authors analyzed National Health and Nutrition Examination Survey data for 1999-2002 to determine the proportion of US adolescents (12-19 years) who would have met each goal prior to dissemination of the 5-2-1-0 recommendations. Merely 0.4% would have met all goals; 41% would have met none. Only 9% consumed greater than or equal to 5 fruits/vegetables, 27% reported 1 hour of physical activity, and 14% consumed no sugar-sweetened beverages per day. Demographic subgroups (eg, racial/ethnic minority and lower income) would have been even farther from meeting the goals. Clinicians are likely to encounter adolescents with nutrition, exercise, and screen time behaviors that are far from 5-2-1-0 goals, and can use these guidelines during clinical encounters to counsel adolescents regarding healthier lifestyles. JF - Clinical Pediatrics AU - Foltz, Jennifer L AU - Cook, Stephen R AU - Szilagyi, Peter G AU - Auinger, Peggy AU - Stewart, Patricia A AU - Bucher, Sophie AU - Dipl, Dietitian AU - Baldwin, Constance D AD - University of Rochester School of Medicine and Dentistry, Rochester, NY, USA, jfoltz@cdc.gov Y1 - 2011/05// PY - 2011 DA - May 2011 SP - 424 EP - 433 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU UK VL - 50 IS - 5 SN - 0009-9228, 0009-9228 KW - Physical Education Index KW - Evaluation KW - Obesity KW - Preventive health KW - Adolescence KW - Analysis KW - Exercise KW - Nutrition KW - Demographics KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1011204752?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+Pediatrics&rft.atitle=US+Adolescent+Nutrition%2C+Exercise%2C+and+Screen+Time+Baseline+Levels+Prior+to+National+Recommendations&rft.au=Foltz%2C+Jennifer+L%3BCook%2C+Stephen+R%3BSzilagyi%2C+Peter+G%3BAuinger%2C+Peggy%3BStewart%2C+Patricia+A%3BBucher%2C+Sophie%3BDipl%2C+Dietitian%3BBaldwin%2C+Constance+D&rft.aulast=Foltz&rft.aufirst=Jennifer&rft.date=2011-05-01&rft.volume=50&rft.issue=5&rft.spage=424&rft.isbn=&rft.btitle=&rft.title=Clinical+Pediatrics&rft.issn=00099228&rft_id=info:doi/10.1177%2F0009922810393499 LA - English DB - Physical Education Index N1 - Date revised - 2012-05-01 N1 - Number of references - 38 N1 - Last updated - 2012-05-07 N1 - SubjectsTermNotLitGenreText - Evaluation; Obesity; Preventive health; Analysis; Adolescence; Exercise; Nutrition; Demographics DO - http://dx.doi.org/10.1177/0009922810393499 ER - TY - JOUR T1 - Healthcare-use for Major Infectious Disease Syndromes in an Informal Settlement in Nairobi, Kenya AN - 925741360; 201203723 AB - A healthcare-use survey was conducted in the Kibera informal settlement in Nairobi, Kenya, in July 2005 to inform subsequent surveillance in the site for infectious diseases. Sets of standardized questionnaires were administered to 1,542 caretakers and heads of households with one or more child(ren) aged less than five years. The average household-size was 5.1 (range 1-15) persons. Most (90%) resided in a single room with monthly rents of US$ 4.50-7.00. Within the previous two weeks, 49% of children (n=1,378) aged less than five years (under-five children) and 18% of persons (n=1,139) aged =5 years experienced febrile, diarrhoeal or respiratory illnesses. The large majority (>75%) of illnesses were associated with health care-seeking. While licensed clinics were the most-frequently visited settings, kiosks, unlicensed care providers, and traditional healers were also frequently visited. Expense was cited most often (50%) as the reason for not seeking healthcare. Of those who sought healthcare, 34-44% of the first and/or the only visits were made with non-licensed care providers, potentially delaying opportunities for early optimal intervention. Adapted from the source document. JF - Journal of Health, Population and Nutrition AU - Breiman, Robert F AU - Olack, Beatrice AU - Shultz, Alvin AU - Roder, Sanam AU - Kimani, Kabuiya AU - Feikin, Daniel R AU - Burke, Heather AD - Kenya Medical Research Institute-CDC rbreiman@ke.cdc.gov Y1 - 2011/04// PY - 2011 DA - April 2011 SP - 123 EP - 133 PB - ICDDR, B, Dhaka, Bangladesh VL - 29 IS - 2 SN - 1606-0997, 1606-0997 KW - Acute respiratory infection KW - Diarrhoeal diseases KW - Febrile illness KW - Healthcare-seeking KW - Health care use KW - Informal settlements KW - Pneumonia KW - Slums KW - Urbanization KW - Kenya KW - Health professionals KW - Health care KW - Settlements KW - Rents KW - Children KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/925741360?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Health%2C+Population+and+Nutrition&rft.atitle=Healthcare-use+for+Major+Infectious+Disease+Syndromes+in+an+Informal+Settlement+in+Nairobi%2C+Kenya&rft.au=Breiman%2C+Robert+F%3BOlack%2C+Beatrice%3BShultz%2C+Alvin%3BRoder%2C+Sanam%3BKimani%2C+Kabuiya%3BFeikin%2C+Daniel+R%3BBurke%2C+Heather&rft.aulast=Breiman&rft.aufirst=Robert&rft.date=2011-04-01&rft.volume=29&rft.issue=2&rft.spage=123&rft.isbn=&rft.btitle=&rft.title=Journal+of+Health%2C+Population+and+Nutrition&rft.issn=16060997&rft_id=info:doi/ L2 - http://www.icddrb.org/jhpn LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2012-03-01 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Settlements; Health care; Kenya; Health professionals; Children; Rents ER - TY - JOUR T1 - Detection of bacterial pathogens in Mongolia meningitis surveillance with a new real-time PCR assay to detect Haemophilus influenzae AN - 923207820; 14919936 AB - Since the implementation of Haemophilus influenzae (Hi) serotype b vaccine, other serotypes and non-typeable strains have taken on greater importance as a cause of Hi diseases. A rapid and accurate method is needed to detect all Hi regardless of the encapsulation status. We developed 2 real-time PCR (rt-PCR) assays to detect specific regions of the protein D gene (hpd). Both hpd assays are very specific and sensitive for detection of Hi. Of the 63 non-Hi isolates representing 21 bacterial species, none was detected by the hpd #1 assay, and only one of 2 H. aphrophilus isolates was detected by the hpd #3 assay. The hpd #1 and #3 assays detected 97% (229/237) and 99% (234/237) of Hi isolates, respectively, and were superior for detection of both typeable and non-typeable Hi isolates, as compared to previously developed rt-PCR targeting ompP2 or bexA. The diagnostic sensitivity and specificity of these rt-PCR assays were assessed on cerebrospinal fluid specimens collected as part of meningitis surveillance in Ulaanbaatar, Mongolia. The etiology (Neisseria meningitidis, Hi, and Streptococcus pneumoniae) of 111 suspected meningitis cases was determined by conventional methods (culture and latex agglutination), previously developed rt-PCR assays, and the new hpd assays. The rt-PCR assays were more sensitive for detection of meningitis pathogens than other classical methods and improved detection from 50% (56/111) to 75% (83/111). The hpd #3 assay identified a non-b Hi that was missed by the bexA assay and other methods. A sensitive rt-PCR assay to detect both typeable and non-typeable Hi is a useful tool for improving Hi disease surveillance especially after Hib vaccine introduction. JF - International Journal of Medical Microbiology AU - Wang, Xin AU - Mair, Raydel AU - Hatcher, Cynthia AU - Theodore, MJordan AU - Edmond, Karen AU - Wu, Henry M AU - Harcourt, Brian H AU - Carvalho, Maria da Gloria S AU - Pimenta, Fabiana AU - Nymadawa, Pagbajab AU - Altantsetseg, Dorjpurev AU - Kirsch, Mariah AU - Satola, Sarah W AU - Cohn, Amanda AU - Messonnier, Nancy E AU - Mayer, Leonard W AD - Meningitis and Vaccine Preventable Diseases Branch, Division of Bacterial Diseases, National Center of Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA, xwang2@cdc.gov Y1 - 2011/04// PY - 2011 DA - Apr 2011 SP - 303 EP - 309 PB - Elsevier GmbH, Office Jena, P.O. Box 100537 Jena D-07705 Germany VL - 301 IS - 4 SN - 1438-4221, 1438-4221 KW - Microbiology Abstracts B: Bacteriology KW - Bacteria KW - Etiology KW - Haemophilus influenzae KW - Serotypes KW - protein D KW - Latex agglutination KW - Neisseria meningitidis KW - Pathogens KW - Meningitis KW - Encapsulation KW - Streptococcus pneumoniae KW - Cerebrospinal fluid KW - Polymerase chain reaction KW - Vaccines KW - J 02310:Genetics & Taxonomy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/923207820?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Medical+Microbiology&rft.atitle=Detection+of+bacterial+pathogens+in+Mongolia+meningitis+surveillance+with+a+new+real-time+PCR+assay+to+detect+Haemophilus+influenzae&rft.au=Wang%2C+Xin%3BMair%2C+Raydel%3BHatcher%2C+Cynthia%3BTheodore%2C+MJordan%3BEdmond%2C+Karen%3BWu%2C+Henry+M%3BHarcourt%2C+Brian+H%3BCarvalho%2C+Maria+da+Gloria+S%3BPimenta%2C+Fabiana%3BNymadawa%2C+Pagbajab%3BAltantsetseg%2C+Dorjpurev%3BKirsch%2C+Mariah%3BSatola%2C+Sarah+W%3BCohn%2C+Amanda%3BMessonnier%2C+Nancy+E%3BMayer%2C+Leonard+W&rft.aulast=Wang&rft.aufirst=Xin&rft.date=2011-04-01&rft.volume=301&rft.issue=4&rft.spage=303&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Medical+Microbiology&rft.issn=14384221&rft_id=info:doi/10.1016%2Fj.ijmm.2010.11.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-02-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Etiology; Cerebrospinal fluid; Serotypes; Latex agglutination; protein D; Polymerase chain reaction; Vaccines; Pathogens; Encapsulation; Meningitis; Bacteria; Streptococcus pneumoniae; Haemophilus influenzae; Neisseria meningitidis DO - http://dx.doi.org/10.1016/j.ijmm.2010.11.004 ER - TY - JOUR T1 - The Utility of Animal Surveillance in the Detection of West Nile Virus Activity in Puerto Rico, 2007 AN - 920802894; 16155114 AB - After the isolation of West Nile virus (WNV) from humans, mosquitoes, and chickens in 2007, an analysis of animal surveillance involving multiple species (horses, monkeys, sheep, dogs, and birds) used to track WNV transmission from 2006 to 2008 was performed. During this period 13.4% of all the animal samples collected were seropositive by blocking ELISA for WNV. The most complete island-wide sampling was obtained from horses of which 22% were serctogically positive and 96% were confirmed as WNV infections by plaque-reduction neutralization test Our conclusion from this 3-year study is that animal surveillance is an early indicator of WNV activity before the identification of human cases. Additionally, the results indicated that horses have a greater geographical range and should be continued to be used as sentinels for passive surveillance in the tropics. JF - Vector Borne and Zoonotic Diseases AU - Phoutrides, E AU - Jusino-Mendez, T AU - Perez-Medina, T AU - Seda-Lozada, R AU - Garcia-Negron, M AU - Davila-Toro, F AU - Hunsperger, E AD - Division of Vector Borne Infectious Diseases, Dengue Branch, Centers for Disease Control and Prevention, 1324 Calle Canada, San Juan 00920, Puerto Rico, enh4@cdc.gov Y1 - 2011/04// PY - 2011 DA - April 2011 SP - 447 EP - 450 VL - 11 IS - 4 SN - 1530-3667, 1530-3667 KW - ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Virology & AIDS Abstracts KW - Enzyme-linked immunosorbent assay KW - Surveillance and enforcement KW - Vectors KW - Man-induced effects KW - Hosts KW - Infection KW - Disease transmission KW - Public health KW - ASW, Caribbean Sea, Greater Antilles, Puerto Rico KW - ELISA KW - Sampling KW - Aquatic insects KW - West Nile virus KW - V 22410:Animal Diseases KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/920802894?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vector+Borne+and+Zoonotic+Diseases&rft.atitle=The+Utility+of+Animal+Surveillance+in+the+Detection+of+West+Nile+Virus+Activity+in+Puerto+Rico%2C+2007&rft.au=Phoutrides%2C+E%3BJusino-Mendez%2C+T%3BPerez-Medina%2C+T%3BSeda-Lozada%2C+R%3BGarcia-Negron%2C+M%3BDavila-Toro%2C+F%3BHunsperger%2C+E&rft.aulast=Phoutrides&rft.aufirst=E&rft.date=2011-04-01&rft.volume=11&rft.issue=4&rft.spage=447&rft.isbn=&rft.btitle=&rft.title=Vector+Borne+and+Zoonotic+Diseases&rft.issn=15303667&rft_id=info:doi/10.1089%2Fvbz.2010.0011 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-02-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Surveillance and enforcement; ELISA; Man-induced effects; Hosts; Aquatic insects; Public health; Disease transmission; Enzyme-linked immunosorbent assay; Vectors; Sampling; Infection; West Nile virus; ASW, Caribbean Sea, Greater Antilles, Puerto Rico DO - http://dx.doi.org/10.1089/vbz.2010.0011 ER - TY - JOUR T1 - Laboratory Diagnosis of Tuberculosis in Resource-Poor Countries: Challenges and Opportunities AN - 918060096; 16062869 AB - Summary: With an estimated 9.4 million new cases globally, tuberculosis (TB) continues to be a major public health concern. Eighty percent of all cases worldwide occur in 22 high-burden, mainly resource-poor settings. This devastating impact of tuberculosis on vulnerable populations is also driven by its deadly synergy with HIV. Therefore, building capacity and enhancing universal access to rapid and accurate laboratory diagnostics are necessary to control TB and HIV-TB coinfections in resource-limited countries. The present review describes several new and established methods as well as the issues and challenges associated with implementing quality tuberculosis laboratory services in such countries. Recently, the WHO has endorsed some of these novel methods, and they have been made available at discounted prices for procurement by the public health sector of high-burden countries. In addition, international and national laboratory partners and donors are currently evaluating other new diagnostics that will allow further and more rapid testing in point-of-care settings. While some techniques are simple, others have complex requirements, and therefore, it is important to carefully determine how to link these new tests and incorporate them within a country's national diagnostic algorithm. Finally, the successful implementation of these methods is dependent on key partnerships in the international laboratory community and ensuring that adequate quality assurance programs are inherent in each country's laboratory network. JF - Clinical Microbiology Reviews AU - Parsons, Linda M AU - Somoskovi, Akos AU - Gutierrez, Cristina AU - Lee, Evan AU - Paramasivan, C N AU - Abimiku, Alash'le AU - Spector, Steven AU - Roscigno, Giorgio AU - Nkengasong, John AD - Centers for Disease Control and Prevention, Global AIDS Program, International Laboratory Branch, Atlanta, Georgia, JNkengasong@cdc.gov Y1 - 2011/04// PY - 2011 DA - Apr 2011 SP - 314 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 24 IS - 2 SN - 0893-8512, 0893-8512 KW - Microbiology Abstracts B: Bacteriology KW - Human immunodeficiency virus KW - Mycobacterium KW - Quality control KW - Algorithms KW - Tuberculosis KW - Public health KW - J 02300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/918060096?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+Microbiology+Reviews&rft.atitle=Laboratory+Diagnosis+of+Tuberculosis+in+Resource-Poor+Countries%3A+Challenges+and+Opportunities&rft.au=Parsons%2C+Linda+M%3BSomoskovi%2C+Akos%3BGutierrez%2C+Cristina%3BLee%2C+Evan%3BParamasivan%2C+C+N%3BAbimiku%2C+Alash%27le%3BSpector%2C+Steven%3BRoscigno%2C+Giorgio%3BNkengasong%2C+John&rft.aulast=Parsons&rft.aufirst=Linda&rft.date=2011-04-01&rft.volume=24&rft.issue=2&rft.spage=314&rft.isbn=&rft.btitle=&rft.title=Clinical+Microbiology+Reviews&rft.issn=08938512&rft_id=info:doi/10.1128%2FCMR.00059-10 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-01-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Quality control; Algorithms; Tuberculosis; Public health; Mycobacterium; Human immunodeficiency virus DO - http://dx.doi.org/10.1128/CMR.00059-10 ER - TY - JOUR T1 - Correlates of Forced Sex Among Populations of Men Who Have Sex with Men in Thailand AN - 904469085; 14435814 AB - Although forced sex is a correlate of HIV infection, its prevalence and associated risks are not well described among men who have sex with men (MSM) in developing-country settings. Between March and October 2005, we assessed the prevalence of forced sex and correlates among populations of MSM (this includes general MSM, male sex workers, and male-to-female transgender persons) in Thailand using a community-based sample. Participants were enrolled from venues around Bangkok, Chiangmai, and Phuket using venue day-time sampling. Handheld computer-assisted self-interviewing was used to collect demographic and behavioral data and logistic regression evaluated factors associated with forced sex, defined as ever being forced to have sexual intercourse against one's will. Of the 2,049 participants (M age, 24.8years), a history of forced sex was reported by 376 (18.4%) men and, of these, most were forced by someone they knew (83.8%), forced more than once (67.3%), and had first occurrence during adolescence (55.1%). In multivariate analysis, having a history of forced sex was significantly associated with being recruited in Phuket, classification as general MSM or transgender (versus classification as male sex worker), drug use, increased number of male sexual partners, and buying sex. The findings in our assessment were consistent with assessments from Western countries. Longitudinal studies are needed to understand the mechanisms of the relationships between forced sex correlates found in our assessment and HIV acquisition and transmission risks. JF - Archives of Sexual Behavior AU - Guadamuz, Thomas E AU - Wimonsate, Wipas AU - Varangrat, Anchalee AU - Phanuphak, Praphan AU - Jommaroeng, Rapeepun AU - Mock, Philip A AU - Tappero, Jordan W AU - Griensven, Frits AD - Thailand Ministry of Public Health-U.S. Centers for Disease Control and Prevention Collaboration, DDC7 Building, Nonthaburi, 11000, Thailand, fav1@cdc.gov Y1 - 2011/04// PY - 2011 DA - Apr 2011 SP - 259 EP - 266 PB - Springer New York, LLC, 233 Spring St New York NY 10013-1578 USA VL - 40 IS - 2 SN - 0004-0002, 0004-0002 KW - Risk Abstracts KW - Historical account KW - Human immunodeficiency virus KW - classification KW - homosexuality KW - Thailand, Chacoengsao Prov., Bangkok KW - bisexuality KW - sexual assault KW - community involvement KW - longitudinal studies KW - Adolescents KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/904469085?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Archives+of+Sexual+Behavior&rft.atitle=Correlates+of+Forced+Sex+Among+Populations+of+Men+Who+Have+Sex+with+Men+in+Thailand&rft.au=Guadamuz%2C+Thomas+E%3BWimonsate%2C+Wipas%3BVarangrat%2C+Anchalee%3BPhanuphak%2C+Praphan%3BJommaroeng%2C+Rapeepun%3BMock%2C+Philip+A%3BTappero%2C+Jordan+W%3BGriensven%2C+Frits&rft.aulast=Guadamuz&rft.aufirst=Thomas&rft.date=2011-04-01&rft.volume=40&rft.issue=2&rft.spage=259&rft.isbn=&rft.btitle=&rft.title=Archives+of+Sexual+Behavior&rft.issn=00040002&rft_id=info:doi/10.1007%2Fs10508-009-9557-8 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Historical account; Human immunodeficiency virus; classification; homosexuality; bisexuality; community involvement; sexual assault; Adolescents; longitudinal studies; Thailand, Chacoengsao Prov., Bangkok DO - http://dx.doi.org/10.1007/s10508-009-9557-8 ER - TY - JOUR T1 - Combining Culture Techniques for Bartonella: the Best of Both Worlds AN - 899162611; 15404020 AB - In this study we compared some common Bartonella culturing methodologies using four diverse species causing human illnesses. Based on a review of the literature, we focused on three major inconsistencies between protocols: base medium, cell coculture, and temperature. Our data showed that Bartonella tamiae demonstrated temperature-dependent growth limitations between common culturing conditions only 2 degree C apart. Additionally, growth of B. quintana was significantly enhanced by the presence of mammalian cell coculture under mammalian cell culture conditions; however, when the medium was modified to incorporate insect cell culture-based medium, coculturing with mammalian cells was no longer needed. In this study, we were able to overcome these temperature- and cell-dependent limitations and accommodate all of the strains tested by combining mammalian cell culture-based medium with insect cell culture-based medium. JF - Journal of Clinical Microbiology AU - Iverson, Jennifer AU - Kosoy, Michael AU - Lynch, Tarah AD - Centers for Disease Control and Prevention, Division of Vector Borne Diseases, Fort Collins, Colorado, mck3@cdc.gov Y1 - 2011/04// PY - 2011 DA - Apr 2011 SP - 1363 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 49 IS - 4 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Temperature effects KW - Data processing KW - Mammalian cells KW - Bartonella KW - Insect cells KW - Reviews KW - Cell culture KW - J 02410:Animal Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/899162611?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Combining+Culture+Techniques+for+Bartonella%3A+the+Best+of+Both+Worlds&rft.au=Iverson%2C+Jennifer%3BKosoy%2C+Michael%3BLynch%2C+Tarah&rft.aulast=Iverson&rft.aufirst=Jennifer&rft.date=2011-04-01&rft.volume=49&rft.issue=4&rft.spage=1363&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.02403-10 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Number of references - 36 N1 - Last updated - 2013-07-15 N1 - SubjectsTermNotLitGenreText - Temperature effects; Data processing; Mammalian cells; Reviews; Insect cells; Cell culture; Bartonella DO - http://dx.doi.org/10.1128/JCM.02403-10 ER - TY - JOUR T1 - Genotoxicity of carbon nanofibers: Are they potentially more or less dangerous than carbon nanotubes or asbestos? AN - 874188516; 14604192 AB - The production of carbon nanofibers and nanotubes (CNF/CNT) and their composite products is increasing globally. CNF are generating great interest in industrial sectors such as energy production and electronics, where alternative materials may have limited performance or are produced at a much higher cost. However, despite the increasing industrial use of carbon nanofibers, information on their potential adverse health effects is limited. In the current study, we examine the cytotoxic and genotoxic potential of carbon-based nanofibers (PyrografA registered -III) and compare this material with the effects of asbestos fibers (crocidolite) or single-walled carbon nanotubes (SWCNT). The genotoxic effects in the lung fibroblast (V79) cell line were examined using two complementary assays: the comet assay and micronucleus (MN) test. In addition, we utilized fluorescence in situ hybridization to detect the chromatin pan-centromeric signals within the MN indicating their origin by aneugenic (chromosomal malsegregation) or clastogenic (chromosome breakage) mechanisms. Cytotoxicity tests revealed a concentration- and time-dependent loss of V79 cell viability after exposure to all tested materials in the following sequence: asbestos>CNF>SWCNT. Additionally, cellular uptake and generation of oxygen radicals was seen in the murine RAW264.7 macrophages following exposure to CNF or asbestos but not after administration of SWCNT. DNA damage and MN induction were found after exposure to all tested materials with the strongest effect seen for CNF. Finally, we demonstrated that CNF induced predominately centromere-positive MN in primary human small airway epithelial cells (SAEC) indicating aneugenic events. Further investigations are warranted to elucidate the possible mechanisms involved in CNF-induced genotoxicity. JF - Toxicology and Applied Pharmacology AU - Kisin, E R AU - Murray, A R AU - Sargent, L AU - Lowry, D AU - Chirila, M AU - Siegrist, K J AU - Schwegler-Berry, D AU - Leonard, S AU - Castranova, V AU - Fadeel, B AU - Kagan, V E AU - Shvedova, A A AD - Pathology and Physiology Research Branch, Health Effects Lab Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA, AShvedova@cdc.gov AShvedova@cdc.gov AShvedova@cdc.gov Y1 - 2011/04/01/ PY - 2011 DA - 2011 Apr 01 SP - 1 EP - 10 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 252 IS - 1 SN - 0041-008X, 0041-008X KW - Environment Abstracts; Toxicology Abstracts KW - Macrophages KW - Epithelial cells KW - Chromatin KW - Fibroblasts KW - Chromosomes KW - Carbon KW - Reactive oxygen species KW - Manganese KW - Respiratory tract KW - Fluorescence in situ hybridization KW - Asbestos KW - composite materials KW - Fluorescence KW - Genotoxicity KW - Crocidolite KW - Oxygen KW - DNA damage KW - Fibers KW - Cytotoxicity KW - Lung KW - DNA KW - nanotubes KW - Comet assay KW - nanotechnology KW - ENA 03:Energy KW - X 24360:Metals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/874188516?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+Applied+Pharmacology&rft.atitle=Genotoxicity+of+carbon+nanofibers%3A+Are+they+potentially+more+or+less+dangerous+than+carbon+nanotubes+or+asbestos%3F&rft.au=Kisin%2C+E+R%3BMurray%2C+A+R%3BSargent%2C+L%3BLowry%2C+D%3BChirila%2C+M%3BSiegrist%2C+K+J%3BSchwegler-Berry%2C+D%3BLeonard%2C+S%3BCastranova%2C+V%3BFadeel%2C+B%3BKagan%2C+V+E%3BShvedova%2C+A+A&rft.aulast=Kisin&rft.aufirst=E&rft.date=2011-04-01&rft.volume=252&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+Applied+Pharmacology&rft.issn=0041008X&rft_id=info:doi/10.1016%2Fj.taap.2011.02.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-06-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Macrophages; Epithelial cells; Asbestos; Chromatin; Genotoxicity; Crocidolite; Fibroblasts; Fibers; DNA damage; Cytotoxicity; Chromosomes; Carbon; Reactive oxygen species; Lung; nanotubes; Comet assay; Manganese; Fluorescence in situ hybridization; Respiratory tract; Oxygen; Fluorescence; composite materials; DNA; nanotechnology DO - http://dx.doi.org/10.1016/j.taap.2011.02.001 ER - TY - JOUR T1 - The impact of CYP2E1 genetic variability on risk assessment of VOC mixtures AN - 867741245; 14604107 AB - Humans are simultaneously exposed to multiple chemicals in the environment. Many of the chemicals use the same enzymes in their metabolic pathways. Competitive inhibition may occur as one of the possible interactions between the xenobiotics in human body. For example, many volatile organic compounds (VOCs) are metabolized using P450 enzymes, specifically CYP2E1. Inheritable gene alterations may result in changes of function of the enzymes in different human subpopulations. Variations in quantity and/or quality of particular isoenzymes may cause differences in the metabolism of VOCs. These variations may cause higher sensitivity in certain populations. Using examples of three different mixtures, this review paper outlines the variances in CYP2E1 isoenzymes, effect of exposure to such mixtures on sensitive populations, and approaches to mixtures risk assessment. JF - Regulatory Toxicology and Pharmacology AU - Pohl, Hana R AU - Scinicariello, Franco AD - Agency for Toxic Substances and Disease Registry, US Department of Health and Human Services, Atlanta, GA 30333, USA, hpohl@cdc.gov Y1 - 2011/04// PY - 2011 DA - Apr 2011 SP - 364 EP - 374 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 59 IS - 3 SN - 0273-2300, 0273-2300 KW - Genetics Abstracts; Environment Abstracts; Pollution Abstracts; Risk Abstracts; Toxicology Abstracts KW - Chemicals KW - Risk assessment KW - Sensitivity KW - Subpopulations KW - Enzymes KW - Xenobiotics KW - subpopulations KW - Reviews KW - Isoenzymes KW - volatile organic compounds KW - Metabolic pathways KW - Volatile organic compounds KW - Metabolism KW - G 07710:Chemical Mutagenesis & Radiation KW - R2 23060:Medical and environmental health KW - X 24350:Industrial Chemicals KW - P 6000:TOXICOLOGY AND HEALTH KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/867741245?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Regulatory+Toxicology+and+Pharmacology&rft.atitle=The+impact+of+CYP2E1+genetic+variability+on+risk+assessment+of+VOC+mixtures&rft.au=Pohl%2C+Hana+R%3BScinicariello%2C+Franco&rft.aulast=Pohl&rft.aufirst=Hana&rft.date=2011-04-01&rft.volume=59&rft.issue=3&rft.spage=364&rft.isbn=&rft.btitle=&rft.title=Regulatory+Toxicology+and+Pharmacology&rft.issn=02732300&rft_id=info:doi/10.1016%2Fj.yrtph.2011.01.013 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-05-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Risk assessment; Subpopulations; Metabolic pathways; volatile organic compounds; Isoenzymes; Enzymes; Xenobiotics; Chemicals; Sensitivity; subpopulations; Reviews; Metabolism; Volatile organic compounds DO - http://dx.doi.org/10.1016/j.yrtph.2011.01.013 ER - TY - JOUR T1 - Surface chemistry of a pine-oil cleaner and other terpene mixtures with ozone on vinyl flooring tiles AN - 864954426; 14525375 AB - Indoor environments are dynamic reactors where consumer products (such as cleaning agents, deodorants, and air fresheners) emit volatile organic compounds (VOCs) that can subsequently interact with indoor oxidants such as ozone (O3), hydroxyl radicals, and nitrate radicals. Typically, consumer products consist of mixtures of VOCs and semi-VOCs which can react in the gas-phase or on surfaces with these oxidants to generate a variety of oxygenated products. In this study, the reaction of a pine-oil cleaner (POC) with O3 (100ppb) on a urethane-coated vinyl flooring tile was investigated at 5% and 50% relative humidity. These results were compared to previous alpha -terpineol+O3 reactions on glass and vinyl surfaces. Additionally, other terpene and terpene alcohol mixtures were formulated to understand the emission profiles as seen in the POC data. Results showed that the alpha -terpineol+O3 reaction products were the prominent species that were also observed in the POC/O3 surface experiments. Furthermore, alpha -terpineol+O3 reactions generate the largest fraction of oxygenated products even in equal mixtures of other terpene alcohols. This finding suggests that the judicial choice of terpene alcohols for inclusion in product formulations may be useful in reducing oxidation product emissions. JF - Chemosphere AU - Ham, Jason E AU - Wells, JRaymond AD - Exposure Assessment Branch, Health Effects Laboratory, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505, United States, bvo2@cdc.gov Y1 - 2011/04// PY - 2011 DA - Apr 2011 SP - 327 EP - 333 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK VL - 83 IS - 3 SN - 0045-6535, 0045-6535 KW - Environment Abstracts; Meteorological & Geoastrophysical Abstracts; Pollution Abstracts KW - Pine oil KW - Ozone KW - Reaction products KW - Surface chemistry KW - Chemicals KW - Relative humidity KW - Alcohol KW - Ozone measurements KW - Consumer products KW - surface chemistry KW - Terpenes in air KW - Humidity KW - Organic compounds in atmosphere KW - Hydroxyl radicals KW - Volatile organic compound emissions KW - Oxidation KW - Emissions KW - Oxidants KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/864954426?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemosphere&rft.atitle=Surface+chemistry+of+a+pine-oil+cleaner+and+other+terpene+mixtures+with+ozone+on+vinyl+flooring+tiles&rft.au=Ham%2C+Jason+E%3BWells%2C+JRaymond&rft.aulast=Ham&rft.aufirst=Jason&rft.date=2011-04-01&rft.volume=83&rft.issue=3&rft.spage=327&rft.isbn=&rft.btitle=&rft.title=Chemosphere&rft.issn=00456535&rft_id=info:doi/10.1016%2Fj.chemosphere.2010.12.036 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-05-01 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Relative humidity; Ozone measurements; Oxidation; Volatile organic compound emissions; Terpenes in air; Organic compounds in atmosphere; Ozone; Chemicals; Alcohol; Consumer products; surface chemistry; Emissions; Humidity; Oxidants; Hydroxyl radicals DO - http://dx.doi.org/10.1016/j.chemosphere.2010.12.036 ER - TY - JOUR T1 - Dynamic oversight: implementation gaps and challenges AN - 1439756765; 18523884 AB - Nanotechnology is touted as a transformative technology in that it is predicted to improve many aspects of human life. There are hundreds of products in the market that utilize nanostructures in their design, such as composite materials made out of carbon or metal oxides. Potential risks to consumers, to the environment, and to workers from the most common passive nanomaterial-carbon nanotubes-are emerging through scientific research. Newer more active nanostructures-such as cancer therapies and targeted drug systems-are also increasing in use and are raising similar risk concerns. Governing the risks to workers is the subject of this commentary. The Occupational Safety and Health Act of 1970 grants the Occupational Safety and Health Administration the legal authority to set occupational health standards to insure that no worker suffers material impairment of health from work. However, setting a standard to protect workers from nanotechnology risks may occur some time in the future because the risks to workers have not been well characterized scientifically. Alternative risk governances-such as dynamic oversight through stakeholder partnerships, "soft law" approaches, and national adoption of international consensus standards-are evaluated in this article. JF - Journal of Nanoparticle Research AU - Howard, John AD - National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Washington, DC, 20201, USA, jhoward1@cdc.gov Y1 - 2011/04// PY - 2011 DA - Apr 2011 SP - 1427 EP - 1434 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 13 IS - 4 SN - 1388-0764, 1388-0764 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Metals KW - Stakeholders KW - Health risks KW - Composite materials KW - Occupational safety KW - Cancer KW - Nanotechnology KW - Occupational health KW - Technology KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1439756765?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Nanoparticle+Research&rft.atitle=Dynamic+oversight%3A+implementation+gaps+and+challenges&rft.au=Howard%2C+John&rft.aulast=Howard&rft.aufirst=John&rft.date=2011-04-01&rft.volume=13&rft.issue=4&rft.spage=1427&rft.isbn=&rft.btitle=&rft.title=Journal+of+Nanoparticle+Research&rft.issn=13880764&rft_id=info:doi/10.1007%2Fs11051-011-0225-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-10-01 N1 - Last updated - 2015-03-20 N1 - SubjectsTermNotLitGenreText - Composite materials; Health risks; Stakeholders; Metals; Occupational safety; Cancer; Technology; Occupational health; Nanotechnology DO - http://dx.doi.org/10.1007/s11051-011-0225-2 ER - TY - JOUR T1 - Impact of the Red River Catastrophic Flood on Women Giving Birth in North Dakota, 1994-2000 AN - 1093472920; 14517421 AB - To document changes in birth rates, birth outcomes, and pregnancy risk factors among women giving birth after the 1997 Red River flood in North Dakota. We analyzed detailed county-level birth files pre-disaster (1994-1996) and post-disaster (1997-2000) in North Dakota. Crude birth rates and adjusted fertility rates were calculated. The demographic and pregnancy risk factors were described among women delivering singleton births. Logistic regression was conducted to examine associations between the disaster and low birth weight (<2,500g), preterm birth (<37weeks), and small for gestational age infants adjusting for confounders. The crude birth rate and direct-adjusted fertility rate decreased significantly after the disaster in North Dakota. The proportion of women giving birth who were older, non-white, unmarried, and had a higher education increased. Compared to pre-disaster, there were significant increases in the following maternal measures after the disaster: any medical risks (5.1-7.1%), anemia (0.7-1.1%), acute or chronic lung disease (0.4-0.5%), eclampsia (0.3-2.1%), and uterine bleeding (0.3-0.4%). In addition, there was a significant increase in births that were low birth weight (OR 1.11, 95% CI 1.03-1.21) and preterm (OR 1.09, 95% CI 1.03-1.16) after adjusting for maternal characteristics and smoking. Following the flood, there was an increase in medical risks, low birth weight, and preterm delivery among women giving birth in North Dakota. Further research that examines birth outcomes of women following a catastrophic disaster is warranted. JF - Maternal and Child Health Journal AU - Tong, Van T AU - Zotti, Marianne E AU - Hsia, Jason AD - Division of Reproductive Health/NCCDPHP, Centers for Disease Control and Prevention, 4770 Buford Hwy, NE, MS-K22, Atlanta, GA, 30341, USA, vtong@cdc.gov Y1 - 2011/04// PY - 2011 DA - Apr 2011 SP - 281 EP - 288 PB - Springer-Verlag (Heidelberg), Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 15 IS - 3 SN - 1092-7875, 1092-7875 KW - Aqualine Abstracts; Water Resources Abstracts KW - Canada, Manitoba, Red R. KW - Disasters KW - AQ 00001:Water Resources and Supplies KW - SW 7010:Education - extramural UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1093472920?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Maternal+and+Child+Health+Journal&rft.atitle=Impact+of+the+Red+River+Catastrophic+Flood+on+Women+Giving+Birth+in+North+Dakota%2C+1994-2000&rft.au=Tong%2C+Van+T%3BZotti%2C+Marianne+E%3BHsia%2C+Jason&rft.aulast=Tong&rft.aufirst=Van&rft.date=2011-04-01&rft.volume=15&rft.issue=3&rft.spage=281&rft.isbn=&rft.btitle=&rft.title=Maternal+and+Child+Health+Journal&rft.issn=10927875&rft_id=info:doi/10.1007%2Fs10995-010-0576-9 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-10-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Disasters; Canada, Manitoba, Red R. DO - http://dx.doi.org/10.1007/s10995-010-0576-9 ER - TY - JOUR T1 - Lack of respiratory improvement following remediation of a water-damaged office building AN - 1017971124; 16691568 AB - Background Damp buildings are commonly remediated without removing employees or ongoing medical surveillance. Methods We examined paired pulmonary function and questionnaire data from 2002 and 2005 for 97 employees in a water-damaged building during ongoing but incomplete remediation. Results We observed no overall improvement in respiratory health, as reflected in symptom scores, overall medication use, spirometry abnormalities, or sick leave. Four employees went from borderline bronchial hyperresponsiveness to bronchial hyperresponsiveness; six developed abnormal spirometry; three more reported post-occupancy current asthma, and four hypersensitivity pneumonitis. The number of participants without lower respiratory symptoms decreased from 27 in 2002 to 20 in 2005. Respiratory cases relocated in the building had a decrease in medication use and sick leave in 2005. Conclusions During dampness remediation, relocation may be health protective and prevent incident building-related respiratory cases. Without relocation of entire workforces, medical surveillance is advisable for secondary prevention of existing building-related disease. Am. J. Ind. Med. 54:269-277, 2011. ? 2010 Wiley-Liss, Inc. JF - American Journal of Industrial Medicine AU - Iossifova, Yulia Y AU - Cox-Ganser, Jean M AU - Park, Ju-Hyeong AU - White, Sandra K AU - Kreiss, Kathleen AD - Epidemic Intelligence Service, Office of Workforce and Career Development, Centers for Disease Control and Prevention, Atlanta, Georgia, sqg8@cdc.gov Y1 - 2011/04// PY - 2011 DA - Apr 2011 SP - 269 EP - 277 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 54 IS - 4 SN - 1097-0274, 1097-0274 KW - Pollution Abstracts; Health & Safety Science Abstracts KW - hypersensitivity KW - Prevention KW - Bioremediation KW - prevention KW - Asthma KW - Respiratory diseases KW - Respiratory function KW - Buildings KW - Drugs KW - P 9999:GENERAL POLLUTION KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1017971124?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Lack+of+respiratory+improvement+following+remediation+of+a+water-damaged+office+building&rft.au=Iossifova%2C+Yulia+Y%3BCox-Ganser%2C+Jean+M%3BPark%2C+Ju-Hyeong%3BWhite%2C+Sandra+K%3BKreiss%2C+Kathleen&rft.aulast=Iossifova&rft.aufirst=Yulia&rft.date=2011-04-01&rft.volume=54&rft.issue=4&rft.spage=269&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=10970274&rft_id=info:doi/10.1002%2Fajim.20910 L2 - http://onlinelibrary.wiley.com/doi/10.1002/ajim.20910/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2013-06-28 N1 - SubjectsTermNotLitGenreText - hypersensitivity; Prevention; Bioremediation; prevention; Asthma; Respiratory function; Respiratory diseases; Drugs; Buildings DO - http://dx.doi.org/10.1002/ajim.20910 ER - TY - JOUR T1 - A model for allocating CDC's HIV prevention resources in the United States AN - 954618198; 14301558 AB - The Division of HIV/AIDS Prevention (DHAP) at the Centers for Disease Control and Prevention has an annual budget of approximately $325 million for funding HIV prevention programs in the U.S. The purpose of this paper is to thoroughly describe the methods used to develop a national HIV resource allocation model intended to inform DHAP on allocation strategies that might improve the overall effectiveness of HIV prevention efforts. The HIV prevention resource allocation problem consists of choosing how to apportion prevention resources among interventions and populations so that HIV incidence is minimized, given a budget constraint. We developed an epidemic model that projects HIV infections over time given a specific allocation scenario. The epidemic model is then embedded in a nonlinear mathematical optimization program to determine the allocation scenario that minimizes HIV incidence over a 5-year horizon. In our model, we consider the general U.S. population and specific at-risk populations. The at-risk populations include 15 subgroups structured by gender, race/ethnicity and HIV transmission risk group. HIV transmission risk groups include high-risk heterosexuals, men who have sex with men and injection drug users. We consider HIV screening interventions and interventions to reduce HIV-related risk behaviors. The output of the model is the optimal funding scenario indicating the amounts to be allocated to all combinations of populations and interventions. For illustrative purposes only, we provide a sample application of the model. In this example, the optimal allocation scenario is compared to the current baseline funding scenario to highlight how the current allocation of funds could be improved. In the baseline allocation, 29% of the annual budget is aimed at the general population, while the model recommends targeting 100% of the budget to the at-risk populations with no allocation targeted to the general population. Within the allocation to behavioral interventions the model recommends an increase in targeting diagnosed positives. Also, the model allocation suggests a greater focus on MSM and IDUs with a 72% of the annual budget allocated to them, while the baseline allocation for MSM and IDUs totals 37%. Incorporating future epidemic trends in the decision-making process informs the selection of populations and interventions that should be targeted. Improving the use of funds by targeting the interventions and population subgroups at greatest risk may lead to improved HIV outcomes. These models can also direct research by pointing to areas where the development of cost-effective interventions can have the most impact on the epidemic. JF - Health Care Management Science AU - Lasry, Arielle AU - Sansom, Stephanie L AU - Hicks, Katherine A AU - Uzunangelov, Vladislav AD - Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road, Mailstop E-48, Atlanta, GA, 30333, USA, alasry@cdc.gov Y1 - 2011/03// PY - 2011 DA - Mar 2011 SP - 115 EP - 124 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 14 IS - 1 SN - 1386-9620, 1386-9620 KW - Risk Abstracts KW - resource allocation KW - USA KW - Acquired immune deficiency syndrome KW - funds KW - disease transmission KW - Human immunodeficiency virus KW - intervention KW - Economics KW - prevention KW - budgets KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/954618198?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+Care+Management+Science&rft.atitle=A+model+for+allocating+CDC%27s+HIV+prevention+resources+in+the+United+States&rft.au=Lasry%2C+Arielle%3BSansom%2C+Stephanie+L%3BHicks%2C+Katherine+A%3BUzunangelov%2C+Vladislav&rft.aulast=Lasry&rft.aufirst=Arielle&rft.date=2011-03-01&rft.volume=14&rft.issue=1&rft.spage=115&rft.isbn=&rft.btitle=&rft.title=Health+Care+Management+Science&rft.issn=13869620&rft_id=info:doi/10.1007%2Fs10729-010-9147-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - resource allocation; Acquired immune deficiency syndrome; funds; disease transmission; Human immunodeficiency virus; intervention; Economics; prevention; budgets; USA DO - http://dx.doi.org/10.1007/s10729-010-9147-2 ER - TY - JOUR T1 - Effective State-Based Surveillance for Multidrug-Resistant Organisms Related to Health Care-Associated Infections AN - 881466053; 2011-104546 AB - In September 2008, the Council of State and Territorial Epidemiologists and the Centers for Disease Control and Prevention sponsored a meeting of public health and infection-control professionals to address the implementation of surveillance for multidrug-resistant organisms (MDROs) -- particularly those related to health care-associated infections. The group discussed the role of health departments and defined goals for future surveillance activities. Participants identified the following main points: (1) surveillance should guide prevention and infection-control activities, (2) an MDRO surveillance system should be adaptable and not organism specific, (3) new systems should utilize and link existing systems, and (4) automated electronic laboratory reporting will be an important component of surveillance but will take time to develop. Current MDRO reporting mandates and surveillance methods vary across states and localities. Health departments that have not already done so should be proactive in determining what type of system, if any, will fit their needs. Adapted from the source document. JF - Public Health Reports AU - Duffy, Jonathan AU - Sievert, Dawn AU - Rebmann, Catherine AU - Kainer, Marion AU - Lynfield, Ruth AU - Smith, Perry AU - Fridkin, Scott AD - Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, 1600 Clifton Rd. NE, MS D-26, Atlanta, GA 30333, Tel. 404-639-4353, Fax 404-639-8834 E-mail: jduffy@cdc.gov Y1 - 2011/03// PY - 2011 DA - March 2011 SP - 176 EP - 185 PB - Oxford University Press, UK VL - 126 IS - 2 SN - 0033-3549, 0033-3549 KW - Law and ethics - Criminal law KW - Government - Internal security KW - Science and technology policy - Science and science policy and research KW - Health conditions and policy - Diseases and disorders KW - Health conditions and policy - Health and health policy KW - Laboratories KW - Diseases KW - Surveillance KW - Public health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/881466053?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Public+Health+Reports&rft.atitle=Effective+State-Based+Surveillance+for+Multidrug-Resistant+Organisms+Related+to+Health+Care-Associated+Infections&rft.au=Duffy%2C+Jonathan%3BSievert%2C+Dawn%3BRebmann%2C+Catherine%3BKainer%2C+Marion%3BLynfield%2C+Ruth%3BSmith%2C+Perry%3BFridkin%2C+Scott&rft.aulast=Duffy&rft.aufirst=Jonathan&rft.date=2011-03-01&rft.volume=126&rft.issue=2&rft.spage=176&rft.isbn=&rft.btitle=&rft.title=Public+Health+Reports&rft.issn=00333549&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2011-08-04 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Surveillance; Laboratories; Diseases; Public health ER - TY - JOUR T1 - Prevalence and Correlates of Sexual Risk Behaviors Among Jamaican Adolescents AN - 881449658; 201114388 AB - Context: Despite high levels of sexual activity and risk behaviors among Jamaican youth, few population-based studies have examined their prevalence or correlates. Methods: The prevalence of three sexual risk behaviors was assessed using data from the 2008-2009 Jamaican Reproductive Health Survey on a subsample of adolescents aged 15-19 who neither were in a union nor had a child. Factors associated with the risk behaviors were examined separately for females and males, using bivariate analysis and multivariate logistic regression. Results: In the year prior to the survey, 32% of females and 54% of males had had sexual intercourse; of those, 12% and 52%, respectively, had had more than one sexual partner, and 49% and 46% had used condoms inconsistently or not at all. School enrollment was protective against females being sexually active and males having multiple partners. Females who were enrolled in an age-appropriate or higher grade had decreased odds of using condoms inconsistently or not at all, and males who were enrolled in a lower than age-appropriate grade had a decreased risk of being sexually active. Males in the lowest wealth tercile were less likely than those in the highest tercile to have been sexually active or to have had multiple partners. Weekly attendance at religious services was protective against all three risk behaviors for both genders, with the exception of inconsistent or no condom use among males. Conclusions: Future reproductive health programs should continue to target adolescents in venues other than schools and churches, and should also address the. Adapted from the source document. JF - International Perspectives on Sexual and Reproductive Health AU - Ishida, Kanako AU - Stupp, Paul AU - McDonald, Olivia AD - Oak Ridge Institute for Science and Education Fellow kishida@cdc.gov Y1 - 2011/03// PY - 2011 DA - March 2011 SP - 6 EP - 15 PB - The Alan Guttmacher Institute, New York NY VL - 37 IS - 1 SN - 1944-0391, 1944-0391 KW - Condoms KW - Sexual behaviour KW - Risk behaviour KW - Jamaican people KW - Adolescents KW - Prevalence KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/881449658?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Perspectives+on+Sexual+and+Reproductive+Health&rft.atitle=Prevalence+and+Correlates+of+Sexual+Risk+Behaviors+Among+Jamaican+Adolescents&rft.au=Ishida%2C+Kanako%3BStupp%2C+Paul%3BMcDonald%2C+Olivia&rft.aulast=Ishida&rft.aufirst=Kanako&rft.date=2011-03-01&rft.volume=37&rft.issue=1&rft.spage=6&rft.isbn=&rft.btitle=&rft.title=International+Perspectives+on+Sexual+and+Reproductive+Health&rft.issn=19440391&rft_id=info:doi/10.1363%2F3700611 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2011-08-04 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Sexual behaviour; Risk behaviour; Condoms; Adolescents; Prevalence; Jamaican people DO - http://dx.doi.org/10.1363/3700611 ER - TY - JOUR T1 - Noise-induced hearing loss in agriculture: creating partnerships to overcome barriers and educate the community on prevention. AN - 863416711; pmid-21368439 AB - Noise-induced hearing loss (NIHL) is a common and preventable injury for farmers. Farmers are frequently exposed to excessive noise, ranking among the top three occupations and industries with the highest risk for hearing loss. Use of hearing protection among farmers is not common. Although the age when NIHL begins among farmers is unknown, its prevalence is higher among male adolescents who live and work on farms. The purpose of this paper is to describe how NIOSH created partnerships to promote hearing conservation for this hard-to-reach population. Partnerships included organizations and individuals who were trusted sources of information for the target population, young farmers 14-35 years of age and their families, and those who had linkages in rural communities. NIOSH engaged partners through exhibits and train-the-trainer workshops at state or national conventions. NIOSH workshops included basic information on NIHL as well as information on free or low-lost resources that participants could use in training others at schools and community events. People with hearing conservation expertise have an important role and many opportunities to improve the knowledge and implementation of hearing conservation among those in agriculture. JF - Noise & health AU - Ehlers, Janet J AU - Graydon, Pamela S AD - National Institute for Occupational Safety and Health, Cincinnati, OH 45226, USA. jehlers@cdc.gov Y1 - 2011/03// PY - 2011 DA - Mar 2011 SP - 142 EP - 146 VL - 13 IS - 51 SN - 1463-1741, 1463-1741 KW - Index Medicus KW - National Library of Medicine KW - Adolescent KW - Adult KW - Agricultural Workers' Diseases: epidemiology KW - *Agricultural Workers' Diseases: prevention & control KW - Cooperative Behavior KW - *Ear Protective Devices: utilization KW - Female KW - *Health Promotion: methods KW - Hearing Loss, Noise-Induced: epidemiology KW - *Hearing Loss, Noise-Induced: prevention & control KW - Humans KW - Male KW - National Institute for Occupational Safety and Health (U.S.) KW - *Occupational Exposure: adverse effects KW - Prevalence KW - United States UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/863416711?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Noise+%26+health&rft.atitle=Noise-induced+hearing+loss+in+agriculture%3A+creating+partnerships+to+overcome+barriers+and+educate+the+community+on+prevention.&rft.au=Ehlers%2C+Janet+J%3BGraydon%2C+Pamela+S&rft.aulast=Ehlers&rft.aufirst=Janet&rft.date=2011-03-01&rft.volume=13&rft.issue=51&rft.spage=142&rft.isbn=&rft.btitle=&rft.title=Noise+%26+health&rft.issn=14631741&rft_id=info:doi/ LA - English (eng) DB - ComDisDome N1 - Date revised - 2011-12-15 N1 - Last updated - 2012-07-13 ER - TY - JOUR T1 - Effects of training on hearing protector attenuation. AN - 863416563; pmid-21368438 AB - The effect of training instruction, whether presented as the manufacturer's printed instructions, a short video training session specific to the product, or as a one-on-one training session was evaluated using four hearing protection devices with eight groups of subjects. Naïve subjects were recruited and tested using three different forms of training: written, video, and individual training. The group averages for A-weighted attenuation were not statistically significant when compared between the video or the written instruction conditions, regardless of presentation order. The experimenter-trained A-weighted attenuations were significantly greater than the written and video instruction for most of the protectors and groups. For each earplug, the noise reduction statistic for A-weighting (NRS A ) and the associated confidence intervals were calculated for the 80 th and 20 th percentiles of protection. Across subject groups for each protector, the differences between NRS A ratings were found to be not statistically significant. Several comparisons evaluating the order of testing, the type of testing, and statistical tests of the performance across the groups are presented. JF - Noise & health AU - Murphy, William J AU - Stephenson, Mark R AU - Byrne, David C AU - Witt, Brad AU - Duran, Jesse AD - National Institute for Occupational Safety and Health, Cincinnati, OH 45226-1998, USA. wjm4@cdc.gov Y1 - 2011/03// PY - 2011 DA - Mar 2011 SP - 132 EP - 141 VL - 13 IS - 51 SN - 1463-1741, 1463-1741 KW - Index Medicus KW - National Library of Medicine KW - Audiometry KW - *Ear Protective Devices KW - *Hearing Loss, Noise-Induced: prevention & control KW - Humans KW - *Inservice Training KW - National Institute for Occupational Safety and Health (U.S.) KW - *Noise, Occupational: adverse effects KW - *Occupational Diseases: prevention & control KW - Reproducibility of Results KW - Teaching Materials KW - United States UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/863416563?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Noise+%26+health&rft.atitle=Effects+of+training+on+hearing+protector+attenuation.&rft.au=Murphy%2C+William+J%3BStephenson%2C+Mark+R%3BByrne%2C+David+C%3BWitt%2C+Brad%3BDuran%2C+Jesse&rft.aulast=Murphy&rft.aufirst=William&rft.date=2011-03-01&rft.volume=13&rft.issue=51&rft.spage=132&rft.isbn=&rft.btitle=&rft.title=Noise+%26+health&rft.issn=14631741&rft_id=info:doi/ LA - English (eng) DB - ComDisDome N1 - Date revised - 2011-12-15 N1 - Last updated - 2012-07-13 ER - TY - JOUR T1 - Relationship between comfort and attenuation measurements for two types of earplugs. AN - 863416531; pmid-21368433 AB - Noise-induced hearing loss is almost always preventable if properly fitted hearing protectors are worn to reduce exposure. Many individuals choose not to wear hearing protection because it may interfere with effective communication in the workplace or it may be uncomfortable. Hearing protector comfort has not received the same amount of attention as noise reduction capability. The present study was conducted to evaluate the comfort level of two different types of insert earplugs as well as the attenuation levels achieved by the earplugs. Attenuation levels were obtained with a commercially available earplug fit-test system, and the comfort ratings were obtained by questionnaire. The primary research objective was to determine whether hearing protector comfort was related to measured attenuation values. A linear mixed effects model provided evidence for an inverse relationship between comfort and attenuation. JF - Noise & health AU - Byrne, David C AU - Davis, Rickie R AU - Shaw, Peter B AU - Specht, Burgundy M AU - Holland, Amy N AD - National Institute for Occupational Safety and Health, Cincinnati, OH, USA. dbyrne@cdc.gov Y1 - 2011/03// PY - 2011 DA - Mar 2011 SP - 86 EP - 92 VL - 13 IS - 51 SN - 1463-1741, 1463-1741 KW - Index Medicus KW - National Library of Medicine KW - Adult KW - *Ear Protective Devices KW - Female KW - *Hearing Loss, Noise-Induced: prevention & control KW - Humans KW - Linear Models KW - Male KW - Middle Aged KW - *Noise, Occupational: adverse effects KW - *Occupational Diseases: prevention & control KW - *Occupational Exposure: adverse effects KW - Prosthesis Design KW - Prosthesis Fitting KW - Questionnaires UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/863416531?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Noise+%26+health&rft.atitle=Relationship+between+comfort+and+attenuation+measurements+for+two+types+of+earplugs.&rft.au=Byrne%2C+David+C%3BDavis%2C+Rickie+R%3BShaw%2C+Peter+B%3BSpecht%2C+Burgundy+M%3BHolland%2C+Amy+N&rft.aulast=Byrne&rft.aufirst=David&rft.date=2011-03-01&rft.volume=13&rft.issue=51&rft.spage=86&rft.isbn=&rft.btitle=&rft.title=Noise+%26+health&rft.issn=14631741&rft_id=info:doi/ LA - English (eng) DB - ComDisDome N1 - Date revised - 2011-12-15 N1 - Last updated - 2012-07-13 ER - TY - JOUR T1 - Rift Valley fever in Kenya: history of epizootics and identification of vulnerable districts AN - 856788703; 14297143 AB - Since Kenya first reported Rift Valley fever (RVF)-like disease in livestock in 1912, the country has reported the most frequent epizootics of RVF disease. To determine the pattern of disease spread across the country after its introduction in 1912, and to identify regions vulnerable to the periodic epizootics, annual livestock disease records at the Department of Veterinary Services from 1910 to 2007 were analysed in order to document the number and location of RVF-infected livestock herds. A total of 38/69 (55%) administrative districts in the country had reported RVF epizootics by the end of 2007. During the 1912-1950 period, the disease was confined to a district in Rift Valley province that is prone to flooding and where livestock were raised in proximity with wildlife. Between 1951 and 2007, 11 national RVF epizootics were recorded with an average inter-epizootic period of 3.6 years (range 1-7 years); in addition, all epizootics occurred in years when the average annual rainfall increased by more than 50% in the affected districts. Whereas the first two national epizootics in 1951 and 1955 were confined to eight districts in the Rift Valley province, there was a sustained epizootic between 1961 and 1964 that spread the virus to over 30% of the districts across six out of eight provinces. The Western and Nyanza provinces, located on the southwestern region of the country, had never reported RVF infections by 2007. The probability of a district being involved in a national epizootic was fivefold higher (62%) in districts that had previously reported disease compared to districts that had no prior disease activity (11%). These findings suggests that once introduced into certain permissive ecologies, the RVF virus becomes enzootic, making the region vulnerable to periodic epizootics that were probably precipitated by amplification of resident virus associated with heavy rainfall and flooding. JF - Epidemiology and Infection AU - Murithi, R M AU - Munyua, P AU - Ithondeka, P M AU - Macharia, J M AU - Hightower, A AU - Luman, E T AU - Breiman, R F AU - Njenga, MKariuki AD - Global Disease Detection Division, U.S. Centers for Disease Control and Prevention - Kenya, Nairobi, Kenya, knjenga@ke.cdc.gov Y1 - 2011/03// PY - 2011 DA - Mar 2011 SP - 372 EP - 380 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU UK VL - 139 IS - 3 SN - 0950-2688, 0950-2688 KW - Virology & AIDS Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - New records KW - Disease spread KW - Rainfall KW - Wildlife KW - Epizootics KW - Rift Valley fever KW - Infection KW - Livestock KW - Disease transmission KW - Kenya KW - Epidemiology KW - Flooding KW - Vulnerability KW - Kenya, Nyanza KW - Rift valleys KW - V 22410:Animal Diseases KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/856788703?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Rift+Valley+fever+in+Kenya%3A+history+of+epizootics+and+identification+of+vulnerable+districts&rft.au=Murithi%2C+R+M%3BMunyua%2C+P%3BIthondeka%2C+P+M%3BMacharia%2C+J+M%3BHightower%2C+A%3BLuman%2C+E+T%3BBreiman%2C+R+F%3BNjenga%2C+MKariuki&rft.aulast=Murithi&rft.aufirst=R&rft.date=2011-03-01&rft.volume=139&rft.issue=3&rft.spage=372&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268810001020 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-03-01 N1 - Number of references - 24 N1 - Last updated - 2014-11-12 N1 - SubjectsTermNotLitGenreText - New records; Epidemiology; Flooding; Vulnerability; Rift valleys; Disease transmission; Disease spread; Rainfall; Wildlife; Rift Valley fever; Epizootics; Infection; Livestock; Kenya; Kenya, Nyanza DO - http://dx.doi.org/10.1017/S0950268810001020 ER - TY - JOUR T1 - Assessing the risk to firefighters from chemical vapors and gases during vehicle fire suppression. AN - 856773414; 21274476 AB - Despite the frequent occurrence of vehicle fires, very few studies investigating firefighters' potential inhalation exposures during vehicle fire suppression have been conducted. In this paper, we present an assessment of firefighters' health risk from vehicle fire suppression that accounts for the mixture of gases and vapors likely to be found in these fires. Summa canisters were used to collect emissions from the engine and cabin fires of a single vehicle and were analyzed for 75 volatile organic compounds (VOCs). Firefighters' breathing zone concentrations (BZCs) of aromatic hydrocarbons, aldehydes, isocyanates, and carbon monoxide were measured during the suppression of three vehicle fires. The Summa canister and BZC data were used to develop a simple model for predicting BZCs for the compounds that were not measured in the firefighters' breathing zones. Hazard quotients (HQs) were calculated by dividing the predicted and measured BZCs by the most conservative short-term exposure limits (STELs) or ceiling limits. Hazard indices (HIs) were determined by adding HQs for compounds grouped by the target organ for acute health effects. Any HIs above unity represented unacceptable risks. According to this mixture analysis, the estimated 95(th) percentile of the exposure distribution for the study population represents ≥ 9.2 times the acceptable level of risk to the respiratory tract and eyes. Furthermore, chemicals known or reasonably anticipated to be human carcinogens contributed to > 45% of these HIs. While STELs are not usually based on carcinogenicity, maintaining exposures below STELs may protect individuals from the biological stress that could result from short-term exposures to carcinogens over time. Although vehicle fires are suppressed quickly (<10 min), this assessment suggests that firefighters have the potential to be overexposed to acute toxins during vehicle fire suppression and should therefore wear self-contained breathing apparatus at all times during vehicle fire response. JF - Journal of environmental monitoring : JEM AU - Fent, Kenneth W AU - Evans, Douglas E AD - Division of Surveillance, Hazard Evaluations, and Field Studies, Lieutenant, US Public Health Service, Industrial Hygienist, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health (CDC/NIOSH), Cincinnati, OH 45226, USA. kfent@cdc.gov Y1 - 2011/03// PY - 2011 DA - March 2011 SP - 536 EP - 543 VL - 13 IS - 3 KW - Air Pollutants, Occupational KW - 0 KW - Gases KW - Volatile Organic Compounds KW - Index Medicus KW - Humans KW - Male KW - Female KW - Risk Assessment KW - Fires KW - Gases -- analysis KW - Air Pollutants, Occupational -- analysis KW - Volatile Organic Compounds -- analysis KW - Occupational Exposure -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/856773414?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+environmental+monitoring+%3A+JEM&rft.atitle=Assessing+the+risk+to+firefighters+from+chemical+vapors+and+gases+during+vehicle+fire+suppression.&rft.au=Fent%2C+Kenneth+W%3BEvans%2C+Douglas+E&rft.aulast=Fent&rft.aufirst=Kenneth&rft.date=2011-03-01&rft.volume=13&rft.issue=3&rft.spage=536&rft.isbn=&rft.btitle=&rft.title=Journal+of+environmental+monitoring+%3A+JEM&rft.issn=1464-0333&rft_id=info:doi/10.1039%2Fc0em00591f LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-06-20 N1 - Date created - 2011-03-10 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1039/c0em00591f ER - TY - JOUR T1 - Interpreting borderline belpt results AN - 1017966865; 16691577 AB - Background The beryllium lymphocyte proliferation test (BeLPT) identifies persons sensitized to beryllium (BeS) and thus at risk for chronic beryllium disease (CBD). BeLPT test results are abnormal (AB), borderline (BL), or normal (NL). This manuscript addresses the predictive value and interpretation of BL BeLPT results. Methods The various three-result combinations that meet or exceed a nominal referral criteria of 1 AB+1 BL are assessed with probability modeling and compared. Results At 2% prevalence, the three-result combinations that meet or exceed this referral criteria and associated probabilities of BeS are: (a) 1 AB+1 BL+1 NL (72%); (b) 3 BL (91%); (c) 2 AB+1 NL (95%); (d) 1 AB+2 BL (99%); (e) 2 AB+1 BL (100%); and (f) 3 AB (100%). Conclusion These results suggest that BL results are meaningful and that three BL results predict BeS across a broad range of population prevalences. An analysis of longitudinal BeLPT results and clinical findings from an actual surveillance program is warranted to confirm the model's predictions. Am. J. Ind. Med. 54:205-209, 2011. ? 2010 Wiley-Liss, Inc. JF - American Journal of Industrial Medicine AU - Middleton, D C AU - Mayer, A S AU - Mroz, M M AU - Maier, L A AD - Agency for Toxic Substances and Disease Registry (ATSDR), Division of Health Studies, Atlanta, Georgia, dmiddleton@cdc.gov Y1 - 2011/03// PY - 2011 DA - Mar 2011 SP - 205 EP - 209 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 54 IS - 3 SN - 1097-0274, 1097-0274 KW - Health & Safety Science Abstracts KW - Beryllium KW - Lymphocytes KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1017966865?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Interpreting+borderline+belpt+results&rft.au=Middleton%2C+D+C%3BMayer%2C+A+S%3BMroz%2C+M+M%3BMaier%2C+L+A&rft.aulast=Middleton&rft.aufirst=D&rft.date=2011-03-01&rft.volume=54&rft.issue=3&rft.spage=205&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=10970274&rft_id=info:doi/10.1002%2Fajim.20909 L2 - http://onlinelibrary.wiley.com/doi/10.1002/ajim.20909/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2012-06-01 N1 - SubjectsTermNotLitGenreText - Beryllium; Lymphocytes DO - http://dx.doi.org/10.1002/ajim.20909 ER - TY - JOUR T1 - Use of the human monocytic leukemia THP-1 cell line and co-incubation with microsomes to identify and differentiate hapten and prohapten sensitizers AN - 856790692; 14344241 AB - Consumer and medical products can contain leachable chemical allergens which can cause skin sensitization. Recent efforts have been directed at the development of non-animal based tests such as in vitro cell activation assays for the identification of skin sensitizers. Prohapten identification by in vitro assays is still problematic due to the lack of prohapten bioactivation. The present study evaluated the effect of hapten and prohapten exposure on cell surface markers expression (CD86, CD54 and CD40) in the human monocytic leukemia, THP-1, cell line. Upregulation of activation and costimulatory markers are key events in the allergic sensitization process and have been reported to serve as indicators of skin sensitization. Cells were exposed to the prohaptens benzo(a)pyrene (BaP), 7,12-dimethylbenz(a)anthracene (DMBA), carvone oxime (COx), cinnamic alcohol (CA) and isoeugenol (IEG) at concentrations ranging from 1 to 10I14M for 24 and 48h. The direct-binding haptens dinitrochlorobenzene (DNCB), benzoquinone (BQ), hydroxylethyl acrylate (HEA) and benzylbromide (BB) were used as positive controls. Cells were also exposed to the irritants sodium dodecyl sulfate (SDS) and sulfanilamide (SFA). Bioactivation of prohaptens was achieved by adding aroclor-induced rat liver microsomes (S9) to the cell cultures. Consistent upregulation of surface expressions of CD86, CD54 (ICAM-1) and CD40 was observed in THP-1 cells treated with direct-acting haptens (A plus or minus S9) or prohapten (+S9). Upregulation of these markers was not observed after exposure to skin irritants or prohaptens in the absence of exogenously added S9. In conclusion, modification of in vitro cell culture assays to include co-incubation with microsomes enhances identification of prohaptens and allows them to be clearly distinguished from direct-binding haptens. JF - Toxicology AU - Chipinda, Itai AU - Ruwona, Tinashe B AU - Templeton, Steven P AU - Siegel, Paul D AD - Allergy and Clinical Immunology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505-2888, United States, IChipinda@cdc.gov Y1 - 2011/02/27/ PY - 2011 DA - 2011 Feb 27 SP - 135 EP - 143 PB - Elsevier Science, P.O. Box 85 Limerick Ireland VL - 280 IS - 3 SN - 0300-483X, 0300-483X KW - Toxicology Abstracts KW - Cell surface KW - CD86 antigen KW - Haptens KW - isoeugenol KW - Sulfanilamide KW - Cell culture KW - Cell activation KW - Tumor cell lines KW - Monocytic leukemia KW - Medical equipment KW - Allergens KW - intercellular adhesion molecule 1 KW - alcohols KW - Consumers KW - CD40 antigen KW - Microsomes KW - Skin KW - Carvone KW - Benzoquinone KW - 9,10-Dimethyl-1,2-benzanthracene KW - oximes KW - Sodium lauryl sulfate KW - Liver KW - Benzo(a)pyrene KW - X 24380:Social Poisons & Drug Abuse UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/856790692?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology&rft.atitle=Use+of+the+human+monocytic+leukemia+THP-1+cell+line+and+co-incubation+with+microsomes+to+identify+and+differentiate+hapten+and+prohapten+sensitizers&rft.au=Chipinda%2C+Itai%3BRuwona%2C+Tinashe+B%3BTempleton%2C+Steven+P%3BSiegel%2C+Paul+D&rft.aulast=Chipinda&rft.aufirst=Itai&rft.date=2011-02-27&rft.volume=280&rft.issue=3&rft.spage=135&rft.isbn=&rft.btitle=&rft.title=Toxicology&rft.issn=0300483X&rft_id=info:doi/10.1016%2Fj.tox.2010.12.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-03-01 N1 - Last updated - 2015-04-09 N1 - SubjectsTermNotLitGenreText - Cell surface; Microsomes; Skin; Haptens; CD86 antigen; Sulfanilamide; isoeugenol; Cell culture; Carvone; Cell activation; Benzoquinone; Tumor cell lines; Monocytic leukemia; Medical equipment; oximes; 9,10-Dimethyl-1,2-benzanthracene; Allergens; intercellular adhesion molecule 1; Liver; Sodium lauryl sulfate; alcohols; Consumers; Benzo(a)pyrene; CD40 antigen DO - http://dx.doi.org/10.1016/j.tox.2010.12.004 ER - TY - JOUR T1 - Human monoclonal antibodies to West Nile virus identify epitopes on the prM protein. AN - 822903803; 21084104 AB - Hybridoma cell lines (2E8, 8G8 and 5G12) producing fully human monoclonal antibodies (hMAbs) specific for the pre-membrane (prM) protein of West Nile virus (WNV) were prepared using a human fusion partner cell line, MFP-2, and human peripheral blood lymphocytes from a blood donor diagnosed with WNV fever in 2004. Using site-directed mutagenesis of a WNV-like particle (VLP) we identified 4 amino acid residues in the prM protein unique to WNV and important in the binding of these hMAbs to the VLP. Residues V19 and L33 are important epitopes for the binding of all three hMAbs. Mutations at residue, T20 and T24 affected the binding of hMAbs, 8G8 and 5G12 only. These hMAbs did not significantly protect AG129 interferon-deficient mice or Swiss Webster outbred mice from WNV infection. Published by Elsevier Inc. JF - Virology AU - Calvert, Amanda E AU - Kalantarov, Gavreel F AU - Chang, Gwong-Jen J AU - Trakht, Ilya AU - Blair, Carol D AU - Roehrig, John T AD - Arboviral Diseases Branch, Division of Vector-Borne Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, U.S. Department of Health and Human Services, 3150 Rampart Rd., Fort Collins, CO 80521, USA. zpz0@cdc.gov Y1 - 2011/02/05/ PY - 2011 DA - 2011 Feb 05 SP - 30 EP - 37 VL - 410 IS - 1 KW - Antibodies, Monoclonal KW - 0 KW - Epitopes KW - Viral Envelope Proteins KW - prM protein, Flavivirus KW - Interferons KW - 9008-11-1 KW - Index Medicus KW - Animals KW - Interferons -- genetics KW - Hybridomas KW - Interferons -- metabolism KW - Models, Molecular KW - Humans KW - Molecular Sequence Data KW - Mice KW - Amino Acid Sequence KW - Cell Line KW - Protein Conformation KW - Mice, Knockout KW - Viral Envelope Proteins -- immunology KW - West Nile virus -- immunology KW - Antibodies, Monoclonal -- metabolism KW - West Nile virus -- metabolism KW - Epitopes -- immunology KW - Antibodies, Monoclonal -- immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/822903803?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Virology&rft.atitle=Human+monoclonal+antibodies+to+West+Nile+virus+identify+epitopes+on+the+prM+protein.&rft.au=Calvert%2C+Amanda+E%3BKalantarov%2C+Gavreel+F%3BChang%2C+Gwong-Jen+J%3BTrakht%2C+Ilya%3BBlair%2C+Carol+D%3BRoehrig%2C+John+T&rft.aulast=Calvert&rft.aufirst=Amanda&rft.date=2011-02-05&rft.volume=410&rft.issue=1&rft.spage=30&rft.isbn=&rft.btitle=&rft.title=Virology&rft.issn=1096-0341&rft_id=info:doi/10.1016%2Fj.virol.2010.10.033 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-02-17 N1 - Date created - 2011-01-07 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.virol.2010.10.033 ER - TY - JOUR T1 - Molecular Determination of H Antigens of Salmonella by Use of a Microsphere-Based Liquid Array AN - 907158430; 14344996 AB - Serotyping of Salmonella has been an invaluable subtyping method for epidemiologic studies for more than 70 years. The technical difficulties of serotyping, primarily in antiserum production and quality control, can be overcome with modern molecular methods. We developed a DNA-based assay targeting the genes encoding the flagellar antigens (fliC and fljB) of the Kauffmann-White serotyping scheme. Fifteen H antigens (H:a, -b, -c, -d, -d/j, -e,h, -i, -k, -r, -y, -z, -z10, -z29, -z35, and -z6), 5 complex major antigens (H:G, -EN, -Z4, -1, and -L) and 16 complex secondary antigens (H:2, -5, -6, -7, -f, -m/g,m, -m/m,t, -p, -s, -t/m,t, -v, -x, -z15, -z24, -z28, and -z51) were targeted in the assay. DNA probes targeting these antigens were designed and evaluated on 500 isolates tested in parallel with traditional serotyping methods. The assay correctly identified 461 (92.2%) isolates based on the 36 antigens detected in the assay. Among the isolates considered correctly identified, 47 (9.4%) were partially serotyped because probes corresponding to some antigens in the strains were not in the assay, and 13 (2.6%) were monophasic or nonmotile strains that possessed flagellar antigen genes that were not expressed but were detected in the assay. The 39 (7.8%) strains that were not correctly identified possessed an antigen that should have been detected by the assay but was not. Apparent false-negative results may be attributed to allelic divergence. The molecular assay provided results that paralleled traditional methods with a much greater throughput, while maintaining the integrity of the Kauffmann-White serotyping scheme, thus providing backwards-compatible epidemiologic data. This assay should greatly enhance the ability of clinical and public health laboratories to serotype Salmonella. JF - Journal of Clinical Microbiology AU - McQuiston, John R AU - Jordan Waters, Blake ADinsmore Matthew LMikoleitand Patricia IFields R AD - Enteric Diseases Laboratory Branch, Division of Foodborne, Waterborne, and Environmental Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, zje8@cdc.gov Y1 - 2011/02// PY - 2011 DA - Feb 2011 SP - 565 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 49 IS - 2 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Serotypes KW - Data processing KW - Quality control KW - DNA probes KW - Probes KW - Serotyping KW - H antigen KW - Salmonella KW - Flagella KW - Public health KW - J 02320:Cell Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/907158430?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Molecular+Determination+of+H+Antigens+of+Salmonella+by+Use+of+a+Microsphere-Based+Liquid+Array&rft.au=McQuiston%2C+John+R%3BJordan+Waters%2C+Blake+ADinsmore+Matthew+LMikoleitand+Patricia+IFields+R&rft.aulast=McQuiston&rft.aufirst=John&rft.date=2011-02-01&rft.volume=49&rft.issue=2&rft.spage=565&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.01323-10 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Number of references - 37 N1 - Last updated - 2013-07-15 N1 - SubjectsTermNotLitGenreText - Data processing; Serotypes; DNA probes; Quality control; Probes; Serotyping; H antigen; Public health; Flagella; Salmonella DO - http://dx.doi.org/10.1128/JCM.01323-10 ER - TY - JOUR T1 - Evaluation of Serum Bactericidal Antibody Assays for Haemophilus influenzae Serotype a AN - 907154736; 14344857 AB - Haemophilus influenzae type a (Hia) is an important pathogen for some American Indian, Alaskan native, and Northern Canada aboriginal populations. Assays to measure serum bactericidal activity (SBA) to Hia have not been developed or validated. Here, we describe two methods for the measurement of SBA: SBA with a viability endpoint (CFU counts) and SBA with a fluorometric endpoint using alamarBlue as the metabolic indicator. Both SBA assays measure Hia-specific functional antibody and correlate with anti-Hia IgG enzyme-linked immunosorbent assay (ELISA) concentration of naturally acquired antibodies. JF - Clinical and Vaccine Immunology AU - Rouphael, Nadine G AU - Satola, Sarah AU - Farley, Monica M AU - Rudolph, Karen AU - Schmidt, Daniel S AU - Gomez-de-Leon, Patricia AU - Robbins, John B AU - Schneerson, Rachel AU - Carlone, George M AU - Romero-Steiner, Sandra AD - Centers for Disease Control and Prevention, 1600 Clifton Road, N.E., Atlanta, Georgia 30333, SSteiner@cdc.gov Y1 - 2011/02// PY - 2011 DA - Feb 2011 SP - 243 EP - 247 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 18 IS - 2 SN - 1556-679X, 1556-679X KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Bacteria KW - Enzyme-linked immunosorbent assay KW - Haemophilus influenzae KW - Serotypes KW - Colony-forming cells KW - Serum bactericidal activity KW - Immunoglobulin G KW - Pathogens KW - F 06905:Vaccines KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/907154736?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+and+Vaccine+Immunology&rft.atitle=Evaluation+of+Serum+Bactericidal+Antibody+Assays+for+Haemophilus+influenzae+Serotype+a&rft.au=Rouphael%2C+Nadine+G%3BSatola%2C+Sarah%3BFarley%2C+Monica+M%3BRudolph%2C+Karen%3BSchmidt%2C+Daniel+S%3BGomez-de-Leon%2C+Patricia%3BRobbins%2C+John+B%3BSchneerson%2C+Rachel%3BCarlone%2C+George+M%3BRomero-Steiner%2C+Sandra&rft.aulast=Rouphael&rft.aufirst=Nadine&rft.date=2011-02-01&rft.volume=18&rft.issue=2&rft.spage=243&rft.isbn=&rft.btitle=&rft.title=Clinical+and+Vaccine+Immunology&rft.issn=1556679X&rft_id=info:doi/10.1128%2FCVI.00219-10 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Enzyme-linked immunosorbent assay; Serotypes; Colony-forming cells; Serum bactericidal activity; Immunoglobulin G; Pathogens; Bacteria; Haemophilus influenzae DO - http://dx.doi.org/10.1128/CVI.00219-10 ER - TY - JOUR T1 - Invited Review: Nanotoxicology-A Pathologist's Perspective AN - 874181757; 14813475 AB - Advances in chemistry and engineering have created a new technology, nanotechnology, involving the tiniest known manufactured products. These products have a rapidly increasing market share and appear poised to revolutionize engineering, cosmetics, and medicine. Unfortunately, nanotoxicology, the study of nanoparticulate health effects, lags behind advances in nanotechnology. Over the past decade, existing literature on ultrafine particles and respirable durable fibers has been supplemented by studies of first-generation nanotechnology products. These studies suggest that nanosizing increases the toxicity of many particulates. First, as size decreases, surface area increases, thereby speeding up dissolution of soluble particulates and exposing more of the reactive surface of durable but reactive particulates. Second, nanosizing facilitates movement of particulates across cellular and intracellular barriers. Third, nanosizing allows particulates to interact with, and sometimes even hybridize with, subcellular structures, including in some cases microtubules and DNA. Finally, nanosizing of some particulates, increases pathologic and physiologic responses, including inflammation, fibrosis, allergic responses, genotoxicity, and carcinogenicity, and may alter cardiovascular and lymphatic function. Knowing how the size and physiochemical properties of nanoparticulates affect bioactivity is important in assuring that the exciting new products of nanotechnology are used safely. This review provides an introduction to the pathology and toxicology of nanoparticulates. JF - Toxicologic Pathology AU - Hubbs, Ann F AU - Mercer, Robert R AU - Benkovic, Stanley A AU - Harkema, Jack AU - Sriram, Krishnan AU - Schwegler-Berry, Diane AU - Goravanahally, Madhusudan P AU - Nurkiewicz, Timothy R AU - Castranova, Vincent AU - Sargent, Linda M AD - Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA, ahubbs@cdc.gov Y1 - 2011/02// PY - 2011 DA - Feb 2011 SP - 301 EP - 324 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU UK VL - 39 IS - 2 SN - 0192-6233, 0192-6233 KW - Toxicology Abstracts KW - Microtubules KW - Fibrosis KW - Surface area KW - Genotoxicity KW - Cosmetics KW - Inflammation KW - Fibers KW - Hypersensitivity KW - Carcinogenicity KW - DNA KW - Dissolution KW - nanoparticles KW - nanotechnology KW - X 24340:Cosmetics, Toiletries & Household Products UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/874181757?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicologic+Pathology&rft.atitle=Invited+Review%3A+Nanotoxicology-A+Pathologist%27s+Perspective&rft.au=Hubbs%2C+Ann+F%3BMercer%2C+Robert+R%3BBenkovic%2C+Stanley+A%3BHarkema%2C+Jack%3BSriram%2C+Krishnan%3BSchwegler-Berry%2C+Diane%3BGoravanahally%2C+Madhusudan+P%3BNurkiewicz%2C+Timothy+R%3BCastranova%2C+Vincent%3BSargent%2C+Linda+M&rft.aulast=Hubbs&rft.aufirst=Ann&rft.date=2011-02-01&rft.volume=39&rft.issue=2&rft.spage=301&rft.isbn=&rft.btitle=&rft.title=Toxicologic+Pathology&rft.issn=01926233&rft_id=info:doi/10.1177%2F0192623310390705 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-06-01 N1 - Number of references - 244 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - Microtubules; Fibrosis; Surface area; Genotoxicity; Cosmetics; Inflammation; Fibers; Hypersensitivity; Carcinogenicity; DNA; Dissolution; nanoparticles; nanotechnology DO - http://dx.doi.org/10.1177/0192623310390705 ER - TY - JOUR T1 - MAKING HIV PREVENTION PROGRAMMING COUNT: IDENTIFYING PREDICTORS OF SUCCESS IN A PARENT-BASED HIV PREVENTION PROGRAM FOR YOUTH AN - 856784178; 14391432 AB - Predictors of change in the number of sexual topics parents discussed and responsiveness during sex communication with their preadolescent after participating in a five-session sexual risk reduction intervention for parents were examined. Data were from 339 African American parents of preado-lescents enrolled in the intervention arm of a randomized-controlled trial of the Parents' Matter! Program (PMP). Four categories of predictors of success were examined: time and resource constraints, personal characteristics, the parent-child relationship, and parent perceptions of child readiness for sex communication. There were only sporadic associations between success and time and resource constraints for either outcome. Parent perception of child readiness for sex communication was positively associated with discussions of sex topics (b = 1.11, confidence interval [CI]: 0.24-1.97) and parental responsiveness (b = .68, CI:0.22-1.15). Although parents face time and resource constraints, most attended at least four sessions, and demographics such as income had limited effects on program success. JF - AIDS Education and Prevention AU - Miller, K S AU - Forehand, R AU - Wiegand, R AU - Fasula, A M AU - Armistead, L AU - Long, N AU - Wyckoff, S C AD - 1600 Clifton Rd. NE, Mailstop E-04; Atlanta, GA 30333, USA, kmiller@cdc.gov Y1 - 2011/02// PY - 2011 DA - Feb 2011 SP - 38 EP - 53 VL - 23 IS - 1 SN - 0899-9546, 0899-9546 KW - Risk Abstracts; Virology & AIDS Abstracts KW - Acquired immune deficiency syndrome KW - Data processing KW - Communication KW - Demography KW - risk reduction KW - Education KW - Communications KW - Human immunodeficiency virus KW - Perception KW - intervention KW - prevention KW - Ethnic groups KW - Sex KW - V 22360:AIDS and HIV KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/856784178?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+Education+and+Prevention&rft.atitle=MAKING+HIV+PREVENTION+PROGRAMMING+COUNT%3A+IDENTIFYING+PREDICTORS+OF+SUCCESS+IN+A+PARENT-BASED+HIV+PREVENTION+PROGRAM+FOR+YOUTH&rft.au=Miller%2C+K+S%3BForehand%2C+R%3BWiegand%2C+R%3BFasula%2C+A+M%3BArmistead%2C+L%3BLong%2C+N%3BWyckoff%2C+S+C&rft.aulast=Miller&rft.aufirst=K&rft.date=2011-02-01&rft.volume=23&rft.issue=1&rft.spage=38&rft.isbn=&rft.btitle=&rft.title=AIDS+Education+and+Prevention&rft.issn=08999546&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-03-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Demography; Data processing; Perception; Communication; Sex; risk reduction; Education; Acquired immune deficiency syndrome; Communications; Human immunodeficiency virus; intervention; prevention; Ethnic groups ER - TY - JOUR T1 - Drowning Mortality in the United States, 1999-2006 AN - 856399497; 2011-42475 AB - Drowning is the fifth leading cause of unintentional fatalities in the US. Our study described demographics and trend analysis of unintentional drowning mortality in the US from 1999 to 2006, and identifies the changes in deaths for specific population subgroups. Mortality data came from the CDC's Web-based Injury Statistics Query and Reporting System. Trends during 1999-2006 were analyzed by gender, age group and race. Annual percentage change in deaths/rates and simple linear regression was used for time-trend analysis from 1999 to 2006, and examines its significance. During 1999-2006, there were 27,514 deaths; 21,668 (78.8%) males, 21,380 (77.7%) whites, and 4,241 (15.4%) aged 00-04years. The annual number of drowning mortality varied from a high of 3,529 in 1999 to a low of 3,281 in 2001. Overall, deaths were increased 1.4% from 3,529 during 1999 to 3,579 deaths during 2006 however, the overall mortality rate decreased by 5%. The proportion of deaths was significantly greater among males than females (27.4 vs. 13.7%: p<0.001) and blacks than among all other races combined (32.5 vs. 21.3%: p<0.001). Fatalities reported from California (n=3,234; 11.75%), Florida (n=2,852; 10.37%) and Texas (n=2,395; 8.70%) accounted for 30.82% of all such deaths in the US. Sub-group analyses showed that drowning mortality decreased 0.72% for males but increased 9.52% for females, the trend differ significantly among males and females (p<0.001). Males, American Indians, and blacks appear to have higher risk of drowning mortality. The trend varied among sexes, age and racial groups from 1999 to 2006. Preventive measures and continuous surveillance is warranted to further decrease these drowning mortalities. Adapted from the source document. JF - Journal of Community Health AU - Nasrullah, Muazzam AU - Muazzam, Sana AD - Injury Control Research Center, West Virginia University, PO Box 9151, Morgantown, WV, 26506, USA snasrullah@cdc.gov Y1 - 2011/02// PY - 2011 DA - February 2011 SP - 69 EP - 75 PB - Springer, New York NY VL - 36 IS - 1 SN - 0094-5145, 0094-5145 KW - Social conditions and policy - Public safety and security KW - Population groups, population policy, and demographics - Demography and census KW - Education and education policy - Statistics, research, research methods, and research support KW - United States KW - Mortality KW - Accidents KW - Statistics KW - Age groups KW - Demographics KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/856399497?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Community+Health&rft.atitle=Drowning+Mortality+in+the+United+States%2C+1999-2006&rft.au=Nasrullah%2C+Muazzam%3BMuazzam%2C+Sana&rft.aulast=Nasrullah&rft.aufirst=Muazzam&rft.date=2011-02-01&rft.volume=36&rft.issue=1&rft.spage=69&rft.isbn=&rft.btitle=&rft.title=Journal+of+Community+Health&rft.issn=00945145&rft_id=info:doi/10.1007%2Fs10900-010-9281-2 LA - English DB - PAIS Index N1 - Date revised - 2011-03-07 N1 - Last updated - 2016-09-28 N1 - CODEN - JCMHBR N1 - SubjectsTermNotLitGenreText - Accidents; Mortality; Statistics; United States; Demographics; Age groups DO - http://dx.doi.org/10.1007/s10900-010-9281-2 ER - TY - JOUR T1 - Impacts of Metal Detector Use in Schools: Insights From 15 Years of Research AN - 855899274; 201107320 AB - BACKGROUND: Multiple approaches exist, both in theory and in practice, to reduce young people's risk of violent victimization when they are in school. Among these approaches, a growing number of school districts are choosing to install metal detectors. We sought to review the literature available on the impacts of metal detectors on school violence and perceptions about school violence. METHODS: We conducted an extensive literature search, including databases for the medical, public health, sociology, and political science literature. Of 128 papers that met our search criteria, 7 studies met inclusion criteria for the literature review. RESULTS: Each of the papers reviewed utilized data that originated from self-report surveys. Four of the studies consisted of secondary analyses of national databases, with the other 3 utilizing local surveys. The studies varied as to the outcome, ranging from student/staff perceptions of safety at school to student self-reports of weapon carrying and/or victimization, and showed mixed results. Several studies suggested potential detrimental effects of metal detectors on student perceptions of safety. One study showed a significant beneficial effect, linking metal detector use to a decrease in the likelihood that students reported carrying a weapon while in school (7.8% vs 13.8%), without a change in weapon carrying in other settings or a decline in participation in physical fights. CONCLUSION: There is insufficient data in the literature to determine whether the presence of metal detectors in schools reduces the risk of violent behavior among students, and some research suggests that the presence of metal detectors may detrimentally impact student perceptions of safety. Adapted from the source document. JF - Journal of School Health AU - Hankin, Abigail AU - Hertz, Marci AU - Simon, Thomas AD - Lead Health Scientist, ( ), National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP), Division of Adolescent and School Health, 4770 Buford Hwy, NE, MS K-40, Atlanta, GA 30341-3717 Y1 - 2011/02// PY - 2011 DA - February 2011 SP - 100 EP - 106 PB - Wiley-Blackwell, UK VL - 81 IS - 2 SN - 0022-4391, 0022-4391 KW - Databases KW - Metals KW - Weapons KW - Perceptions KW - Safety KW - Selfreport KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/855899274?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+School+Health&rft.atitle=Impacts+of+Metal+Detector+Use+in+Schools%3A+Insights+From+15+Years+of+Research&rft.au=Hankin%2C+Abigail%3BHertz%2C+Marci%3BSimon%2C+Thomas&rft.aulast=Hankin&rft.aufirst=Abigail&rft.date=2011-02-01&rft.volume=81&rft.issue=2&rft.spage=100&rft.isbn=&rft.btitle=&rft.title=Journal+of+School+Health&rft.issn=00224391&rft_id=info:doi/10.1111%2Fj.1746-1561.2010.00566.x LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2011-03-07 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Metals; Perceptions; Weapons; Safety; Selfreport; Databases DO - http://dx.doi.org/10.1111/j.1746-1561.2010.00566.x ER - TY - JOUR T1 - Identification and measurement of diacetyl substitutes in dry bakery mix production. AN - 846898128; 21253982 AB - In 2008, a company using multiple buttermilk flavorings in the production of dry bakery mixes replaced one liquid flavoring containing 15-20% diacetyl with a proprietary substitute meant to lower occupational risk for diacetyl-related bronchiolitis obliterans. Subsequently, the National Institute for Occupational Safety and Health (NIOSH) evaluated buttermilk flavoring-related exposures at this company's facility, with a focus on measuring ketones by several methods. Volatile organic compounds (VOCs) were evaluated in the headspaces of six bulk flavorings samples, including the substitute buttermilk flavoring. Ketones were evaluated in workplace air via area and personal samples collected during batch preparation of the substitute buttermilk flavoring and production of a bakery mix containing the same flavoring. Air samples were evaluated using five different methods: NIOSH 2549, Modified OSHA PV2118, OSHA 1013, NIOSH Draft Procedure SMP2, and evacuated canisters. Of five buttermilk flavorings from five different flavorings manufacturers, diacetyl was present in four, including the substitute flavoring; acetoin in two; 2,3-pentanedione in four; 2,3-hexanedione in one; and 2,3-heptanedione in three. Among material safety data sheets (MSDS) for four flavorings, only one listed a hazardous ingredient, which was acetoin. The predominant flavoring ingredient identified in the headspace of the substitute flavoring was 2,3-pentanedione; all other chemicals noted above were also present. Diacetyl and 2,3-pentanedione were measured in workplace air via evacuated canisters. In one area and one personal air sample, 2,3-pentanedione was measured by OSHA Method 1013 at concentrations of 78 and 91 ppb, respectively. Without their or the employer's knowledge, workers who used buttermilk flavorings were exposed to substitute ketones from many flavorings manufacturers. Because 2,3-pentanedione, 2,3-hexanedione, and 2,3-heptanedione all share the same functional α-diketone group as diacetyl, these compounds also may share diacetyl's mechanism of toxicity. Until more is known about 2,3-pentanedione and other α-diketone compounds, they should not be assumed to be safe. Companies using artificial buttermilk flavorings should use a precautionary approach that assumes these flavorings pose a health risk and limit exposures through engineering and administrative controls and use of personal protective equipment. JF - Journal of occupational and environmental hygiene AU - Day, Gregory AU - LeBouf, Ryan AU - Grote, Ardith AU - Pendergrass, Stephanie AU - Cummings, Kristin AU - Kreiss, Kathleen AU - Kullman, Greg AD - Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505-2888, USA. gday@cdc.gov Y1 - 2011/02// PY - 2011 DA - February 2011 SP - 93 EP - 103 VL - 8 IS - 2 KW - Air Pollutants, Occupational KW - 0 KW - Flavoring Agents KW - Ketones KW - Volatile Organic Compounds KW - Diacetyl KW - K324J5K4HM KW - Index Medicus KW - United States KW - Occupational Health KW - Humans KW - Ketones -- analysis KW - Flavoring Agents -- analysis KW - National Institute for Occupational Safety and Health (U.S.) KW - Diacetyl -- analysis KW - Air Pollutants, Occupational -- analysis KW - Diacetyl -- analogs & derivatives KW - Food Handling KW - Volatile Organic Compounds -- analysis KW - Occupational Exposure -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/846898128?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+occupational+and+environmental+hygiene&rft.atitle=Identification+and+measurement+of+diacetyl+substitutes+in+dry+bakery+mix+production.&rft.au=Day%2C+Gregory%3BLeBouf%2C+Ryan%3BGrote%2C+Ardith%3BPendergrass%2C+Stephanie%3BCummings%2C+Kristin%3BKreiss%2C+Kathleen%3BKullman%2C+Greg&rft.aulast=Day&rft.aufirst=Gregory&rft.date=2011-02-01&rft.volume=8&rft.issue=2&rft.spage=93&rft.isbn=&rft.btitle=&rft.title=Journal+of+occupational+and+environmental+hygiene&rft.issn=1545-9632&rft_id=info:doi/10.1080%2F15459624.2011.547148 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-05-03 N1 - Date created - 2011-01-21 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1080/15459624.2011.547148 ER - TY - JOUR T1 - Hypochlorite Solution Expiration and Stability in Household Water Treatment in Developing Countries AN - 1671566617; 14596547 AB - Household water treatment with dilute hypochlorite solution has been shown to improve microbiological water quality and reduce diarrheal disease in developing countries. One concern raised by governmental agencies, implementers, and nongovernmental organizations is whether the hypochlorite solution remains stable during distribution and after the bottle is opened and usage begins. In this study, laboratory and field research was conducted to determine the expiration date and stability in the home of hypochlorite solution. Expiration-date testing found that pH-stabilized ~1.25% hypochlorite solution made using various production techniques in Ethiopia, Guinea, and Nigeria was stable for a minimum of 12 months in temperatures less than 35 degree C. Stability testing during laboratory simulated normal usage showed no degradation, and 77-91% of bottles collected from households tested met standards. Hypochlorite solution concentration drops rapidly when pH is not stabilized, when pH levels fall, and when solution is exposed to direct sunlight. JF - Journal of Environmental Engineering AU - Lantagne, D AU - Preston, K AU - Blanton, E AU - Kotlarz, N AU - Gezagehn, H AU - van Dusen, E AU - Berens, J AU - Jellison, K AD - Public Health Engineer, Enteric Diseases Epidemiology Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd., MS-A38, Atlanta, GA 30333 dlantagne@cdc.gov Y1 - 2011/02// PY - 2011 DA - February 2011 SP - 131 EP - 136 PB - American Society of Civil Engineers, 345 E. 47th St. New York NY 10017-2398 USA VL - 137 IS - 2 SN - 0733-9372, 0733-9372 KW - Environmental Engineering Abstracts (EN); CSA / ASCE Civil Engineering Abstracts (CE); ANTE: Abstracts in New Technologies and Engineering (AN) KW - Developing countries KW - Residential location KW - Water treatment KW - Solutes KW - Expiration KW - Households KW - Microorganisms KW - Standards KW - Stability KW - pH KW - Bottles KW - Yes:(AN) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1671566617?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvironmentalengabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+Engineering&rft.atitle=Hypochlorite+Solution+Expiration+and+Stability+in+Household+Water+Treatment+in+Developing+Countries&rft.au=Lantagne%2C+D%3BPreston%2C+K%3BBlanton%2C+E%3BKotlarz%2C+N%3BGezagehn%2C+H%3Bvan+Dusen%2C+E%3BBerens%2C+J%3BJellison%2C+K&rft.aulast=Lantagne&rft.aufirst=D&rft.date=2011-02-01&rft.volume=137&rft.issue=2&rft.spage=131&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+Engineering&rft.issn=07339372&rft_id=info:doi/10.1061%2F%28ASCE%29EE.1943-7870.0000299 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-06-01 N1 - Last updated - 2017-02-03 DO - http://dx.doi.org/10.1061/(ASCE)EE.1943-7870.0000299 ER - TY - JOUR T1 - Primary Causes of Death in Reported Cases of Fatal West Nile Fever, United States, 2002-2006 AN - 1524406250; 16155015 AB - Morbidity and mortality associated with human West Nile virus (WNV) infection is generally attributable to severe neurologic disease; most illness with WNV, however, is characterized by febrile illness. Although generally considered to be a benign, self-limited syndrome, some cases of West Nile Fever (WNF) have been reported as resulting in fatal outcome. We reviewed cause-of-death information for 35 cases of WNF reported as fatal to the Centers for Disease Control and Prevention between 2002 and 2006, to determine underlying primary causes of death and identify groups at highest risk for fatal WNF. Fifteen were determined to be misclassified neuroinvasive disease cases; one death was medically unrelated to WNV infection. Among the remaining 23 cases, the median age was 78 years (range: 54-92), and 78% were >70 years old; the median age for all 13,482 reported cases of WNF during this time period was 47 years (range: 1 month-97 years). Cardiac (8 cases, 35%) and pulmonary complications (6 cases, 25%) were the most common primary causes of death. Underlying medical conditions among fatal WNF cases included cardiovascular disease (13; 76%), hypertension (8; 47%), and diabetes mellitus (6; 35%). Our study suggests that in some individuals, especially persons of advanced age and those with underlying medical conditions, WNF may precipitate death. The elderly are at increased risk of death from both West Nile neuroinvasive disease and WNF, which emphasizes the importance of primary prevention of WNV infection and close monitoring for cardiac and pulmonary complications in elderly patients hospitalized for WNV disease. JF - Vector Borne and Zoonotic Diseases AU - Sejvar, J J AU - Lindsey, N P AU - Campbell, G L AD - Division of Vector-Borne Infectious Diseases, National Center for Zoonotic, Vectorborne, and Enteric Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, Mail stop A-39, Atlanta, GA 30333, USA, zea3@cdc.gov Y1 - 2011/02// PY - 2011 DA - February 2011 SP - 161 EP - 164 VL - 11 IS - 2 SN - 1530-3667, 1530-3667 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources KW - Symptoms KW - USA KW - Disease control KW - Hosts KW - West Nile virus KW - Mortality causes KW - Disease transmission KW - Public health KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1524406250?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vector+Borne+and+Zoonotic+Diseases&rft.atitle=Primary+Causes+of+Death+in+Reported+Cases+of+Fatal+West+Nile+Fever%2C+United+States%2C+2002-2006&rft.au=Sejvar%2C+J+J%3BLindsey%2C+N+P%3BCampbell%2C+G+L&rft.aulast=Sejvar&rft.aufirst=J&rft.date=2011-02-01&rft.volume=11&rft.issue=2&rft.spage=161&rft.isbn=&rft.btitle=&rft.title=Vector+Borne+and+Zoonotic+Diseases&rft.issn=15303667&rft_id=info:doi/10.1089%2Fvbz.2009.0086 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-05-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Symptoms; Disease control; Hosts; Mortality causes; Public health; Disease transmission; West Nile virus; USA DO - http://dx.doi.org/10.1089/vbz.2009.0086 ER - TY - JOUR T1 - Lipopolysaccharide increases Na super(+),K super(+)-pump, but not ENaC, expression in guinea-pig airway epithelium AN - 968159096; 14183402 AB - Earlier, we found in functional experiments that lipopolysaccharide (LPS; 4 mg/kg; i.p.) hyperpolarized the epithelium by stimulating the transepithelial transport of Na super(+) in guinea-pig tracheal epithelium. Epithelial sodium channel (ENaC) activity and Na super(+),K super(+)-pump activity were increased. In this study, we hypothesized that LPS increases the expression of ENaC and the Na super(+),K super(+)-pump in the epithelium and investigated the levels of transcription and protein abundance. Using qPCR, the effects of LPS on the transcription of alpha ENaC, alpha sub(1) Na super(+),K super(+)-pump, COX-2, eNOS, iNOS, IL-1 beta , and TNF- alpha were measured at 3 and 18 h. In the epithelium, LPS increased the transcription of COX-2, IL-1 beta , and, to a nonsignificant extent, TNF- alpha at 3 h, but not at 18 h. In alveolar macrophages, TNF- alpha , and, to a nonsignificant extent, COX-2 and IL-1 beta were up-regulated at 3 h, but not at 18 h. Even though LPS stimulated the transcription of some genes, alpha ENaC and alpha sub(1) Na super(+),K super(+)-ATPase transcription were not affected. The expressions of alpha -, beta -, and gamma -ENaC and alpha sub(1) Na super(+),K super(+)-pump from the tracheal epithelium and kidney cortex/medulla were investigated by western blotting. All three ENaC subunits were detected as cleavage fragments, yet LPS had no effect on their expression. LPS increased the expression of the alpha sub(1) subunit and the alpha sub(1), alpha sub(2), and alpha sub(3) subunits, collectively, of the Na super(+),K super(+)-pump. Taken together, these data indicate that LPS increases Na super(+) transport downstream of the genetic level, in part, by stimulating the expression of the Na super(+),K super(+)-pump. JF - European Journal of Pharmacology AU - Dodrill, Michael W AU - Beezhold, Donald H AU - Meighan, Terence AU - Kashon, Michael L AU - Fedan, Jeffrey S AD - Department of Basic Pharmaceutical Sciences, School of Pharmacy, Robert C. Byrd Health Sciences Center, West Virginia University, Morgantown, WV 26505, United States, jsf2@cdc.gov Y1 - 2011/01/25/ PY - 2011 DA - 2011 Jan 25 SP - 176 EP - 186 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 651 IS - 1-3 SN - 0014-2999, 0014-2999 KW - Toxicology Abstracts KW - Cyclooxygenase-2 KW - Macrophages KW - Western blotting KW - Data processing KW - renal cortex KW - Interleukin 1 KW - Transcription KW - Alveoli KW - Nitric-oxide synthase KW - Kidney KW - Lipopolysaccharides KW - Epithelium KW - Sodium channels KW - Tumor necrosis factor- alpha KW - Na super(+)/K super(+)-exchanging ATPase KW - Respiratory tract KW - X 24370:Natural Toxins UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/968159096?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=European+Journal+of+Pharmacology&rft.atitle=Lipopolysaccharide+increases+Na+super%28%2B%29%2CK+super%28%2B%29-pump%2C+but+not+ENaC%2C+expression+in+guinea-pig+airway+epithelium&rft.au=Dodrill%2C+Michael+W%3BBeezhold%2C+Donald+H%3BMeighan%2C+Terence%3BKashon%2C+Michael+L%3BFedan%2C+Jeffrey+S&rft.aulast=Dodrill&rft.aufirst=Michael&rft.date=2011-01-25&rft.volume=651&rft.issue=1-3&rft.spage=176&rft.isbn=&rft.btitle=&rft.title=European+Journal+of+Pharmacology&rft.issn=00142999&rft_id=info:doi/10.1016%2Fj.ejphar.2010.10.088 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-01 N1 - Last updated - 2013-12-04 N1 - SubjectsTermNotLitGenreText - Macrophages; Cyclooxygenase-2; Western blotting; Data processing; renal cortex; Interleukin 1; Transcription; Alveoli; Nitric-oxide synthase; Kidney; Lipopolysaccharides; Epithelium; Tumor necrosis factor- alpha; Sodium channels; Na super(+)/K super(+)-exchanging ATPase; Respiratory tract DO - http://dx.doi.org/10.1016/j.ejphar.2010.10.088 ER - TY - JOUR T1 - A Social Vulnerability Index for Disaster Management AN - 861562513; 14343723 AB - Social vulnerability refers to the socioeconomic and demographic factors that affect the resilience of communities. Studies have shown that in disaster events the socially vulnerable are more likely to be adversely affected, i.e. they are less likely to recover and more likely to die. Effectively addressing social vulnerability decreases both human suffering and the economic loss related to providing social services and public assistance after a disaster. This paper describes the development of a social vulnerability index (SVI), from 15 census variables at the census tract level, for use in emergency management. It also examines the potential value of the SVI by exploring the impact of Hurricane Katrina on local populations. JF - Journal of Homeland Security and Emergency Management AU - Flanagan, Barry AU - Gregory, Edward AU - Hallisey, Elaine AU - Heitgerd, Janet AU - Lewis, Brian AD - CDC/ATSDR Y1 - 2011/01/05/ PY - 2011 DA - 2011 Jan 05 SP - 1792 PB - Berkeley Electronic Press, 805 Camelia Street Berkeley CA 94710 USA VL - 8 IS - 1 SN - 1547-7355, 1547-7355 KW - Risk Abstracts KW - social vulnerability KW - Hurricane Katrina KW - census KW - demography KW - social services KW - Hurricanes KW - homeland security KW - Emergency preparedness KW - Economics KW - Disasters KW - vulnerability KW - R2 23070:Economics, organization UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/861562513?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Homeland+Security+and+Emergency+Management&rft.atitle=A+Social+Vulnerability+Index+for+Disaster+Management&rft.au=Flanagan%2C+Barry%3BGregory%2C+Edward%3BHallisey%2C+Elaine%3BHeitgerd%2C+Janet%3BLewis%2C+Brian&rft.aulast=Flanagan&rft.aufirst=Barry&rft.date=2011-01-05&rft.volume=8&rft.issue=1&rft.spage=1792&rft.isbn=&rft.btitle=&rft.title=Journal+of+Homeland+Security+and+Emergency+Management&rft.issn=15477355&rft_id=info:doi/ L2 - http://www.bepress.com/jhsem/vol8/iss1/3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - social services; demography; census; Hurricanes; homeland security; Emergency preparedness; Economics; Disasters; vulnerability ER - TY - JOUR T1 - Microbiologic effectiveness of boiling and safe water storage in South Sulawesi, Indonesia AN - 911162719; 16066869 AB - In Indonesia, where diarrhea remains a major cause of mortality among children <5 years, the government promotes boiling of drinking water. We assessed the impact of boiling on water quality in South Sulawesi. We surveyed randomly selected households with at least one child <5 years old in two rural districts and tested source and stored water samples for Escherichia coli contamination. Among 242 households, 96% of source and 51% of stored water samples yielded E. coli. Unboiled water samples, obtained from 15% of households, were more likely to yield E. coli than boiled samples [prevalence ratios (PR) = 2.0, 95% confidence interval (CI) 1.7--2.5]. Water stored in wide-mouthed (PR = 1.4, 95% CI = 1.1--1.8) or uncovered (PR = 1.8, 95% CI = 1.3--2.4) containers, or observed to be touched by the respondent's hands (PR = 1.6, 95% CI = 1.3--2.1) was more likely to yield E. coli. A multivariable model showed that households that did not boil water were more likely to have contaminated stored water than households that did boil water (PR = 1.9, 95% CI = 1.5--2.3). Although this study demonstrated the effectiveness of boiling in reducing contamination, overall impact on water quality was suboptimal. Future studies are needed to identify factors behind the success of boiling water in Indonesia to inform efforts to scale up other effective water treatment practices. JF - Journal of Water and Health AU - Sodha, Samir V AU - Menon, M AU - Trivedi, K AU - Ati, A AU - Figueroa, M E AU - Ainslie, R AU - Wannemuehler, K AU - Quick, R AD - Centers for Disease Control and Prevention, Division of Foodborne, Waterborne, and Environmental Diseases, 1600 Clifton Road, MS E-05 Atlanta, GA 30333, USA, ssodha@cdc.gov Y1 - 2011 PY - 2011 DA - 2011 SP - 577 EP - 585 PB - IWA Publishing, Alliance House London SW1H 0QS United Kingdom VL - 9 IS - 3 SN - 1477-8920, 1477-8920 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Environment Abstracts; Water Resources Abstracts; Aqualine Abstracts KW - water quality KW - Containers KW - Water sampling KW - Contamination KW - Water Analysis KW - Water Sampling KW - Indonesia KW - Microbial contamination KW - Water quality KW - Yield KW - households KW - Drinking Water KW - Water treatment KW - Escherichia coli KW - Biological pollutants KW - Bacteria (Enterobacteriaceae) (Escherichia) KW - Mortality KW - Pathogenic bacteria KW - Storage life KW - Water Quality KW - Children KW - Indonesia, Sulawesi KW - Water pollution KW - Water Storage KW - Drinking water KW - Mortality causes KW - Rural areas KW - AQ 00001:Water Resources and Supplies KW - Q5 08502:Methods and instruments KW - SW 3060:Water treatment and distribution KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/911162719?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Water+and+Health&rft.atitle=Microbiologic+effectiveness+of+boiling+and+safe+water+storage+in+South+Sulawesi%2C+Indonesia&rft.au=Sodha%2C+Samir+V%3BMenon%2C+M%3BTrivedi%2C+K%3BAti%2C+A%3BFigueroa%2C+M+E%3BAinslie%2C+R%3BWannemuehler%2C+K%3BQuick%2C+R&rft.aulast=Sodha&rft.aufirst=Samir&rft.date=2011-01-01&rft.volume=9&rft.issue=3&rft.spage=577&rft.isbn=&rft.btitle=&rft.title=Journal+of+Water+and+Health&rft.issn=14778920&rft_id=info:doi/10.2166%2Fwh.2011.255 L2 - http://www.iwaponline.com/jwh/009/jwh0090577.htm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-12-01 N1 - Last updated - 2014-05-02 N1 - SubjectsTermNotLitGenreText - Drinking Water; Contamination; Pathogenic bacteria; Storage life; Biological pollutants; Microbial contamination; Water quality; Water pollution; Mortality causes; Containers; Mortality; water quality; households; Water treatment; Water sampling; Children; Drinking water; Rural areas; Bacteria (Enterobacteriaceae) (Escherichia); Yield; Water Analysis; Water Sampling; Water Storage; Water Quality; Escherichia coli; Indonesia; Indonesia, Sulawesi DO - http://dx.doi.org/10.2166/wh.2011.255 ER - TY - JOUR T1 - Genetic Susceptibility and the Setting of Occupational Health Standards AN - 910644647; 15412495 AB - As more is learned about genetic susceptibility to occupational and environmental hazards, there will be increasing pressure to use genetic susceptibility information in setting occupational health standards. Historically, this has not been done, but a growing body of research assesses inherited genetic factors as modifiers of the effects of hazardous exposures. Additionally, acquired genetic and epigenetic characteristics could also be used in standard setting. However, for both inherited and acquired genetic characteristics, many scientific, ethical, legal, and social issues could arise. Investigators need to examine the potential role and implications of using genetic information in standard setting. In this review, we focus primarily on inherited genetic factors and their role in occupational health standard setting. JF - Annual Review of Public Health AU - Schulte, P AU - Howard, J AD - National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, Ohio 45226, USA, pschulte@cdc.gov Y1 - 2011 PY - 2011 DA - 2011 SP - 149 EP - 159 VL - 32 SN - 0163-7525, 0163-7525 KW - Genetics Abstracts; Health & Safety Science Abstracts KW - Historical account KW - Genetic factors KW - environmental hazards KW - Public health KW - epigenetics KW - Reviews KW - Ethics KW - Pressure KW - Occupational health KW - G 07880:Human Genetics KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/910644647?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annual+Review+of+Public+Health&rft.atitle=Genetic+Susceptibility+and+the+Setting+of+Occupational+Health+Standards&rft.au=Schulte%2C+P%3BHoward%2C+J&rft.aulast=Schulte&rft.aufirst=P&rft.date=2011-01-01&rft.volume=32&rft.issue=&rft.spage=149&rft.isbn=&rft.btitle=&rft.title=Annual+Review+of+Public+Health&rft.issn=01637525&rft_id=info:doi/10.1146%2Fannurev-publhealth-031210-101144 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Genetic factors; epigenetics; Ethics; Reviews; Pressure; Public health; Historical account; environmental hazards; Occupational health DO - http://dx.doi.org/10.1146/annurev-publhealth-031210-101144 ER - TY - JOUR T1 - Demographic but not geographic insularity in HIV transmission among young black MSM AN - 907193859; 16073874 AB - Objective: To understand patterns of HIV transmission among young black MSM and others in Mississippi. Design: Phylogenetic analysis of HIV-1 polymerase (pol) sequences from 799 anti-retroviral-naive persons newly diagnosed with HIV infection in Mississippi during 2005-2008, 130 (16%) of whom were black MSM aged 16-25 years. Methods: We identified phylogenetic clusters and used surveillance data to evaluate demographic attributes and risk factors of all persons in clusters that included black MSM aged 16-25 years. Results: We identified 82 phylogenetic clusters, 21 (26%) of which included HIV strains from at least one young black MSM. Of the 69 persons in these clusters, 59 were black MSM and seven were black men with unknown transmission category; the remaining three were MSM of white or Hispanic race/ethnicity. Of these 21 clusters, 10 included residents of one geographic region of Mississippi, whereas 11 included residents of multiple regions or outside of the state. Conclusion: Phylogenetic clusters involving HIV-infected young black MSM were homogeneous with respect to demographic and risk characteristics, suggesting insularity of this population with respect to HIV transmission, but were geographically heterogeneous. Reducing HIV transmission among young black MSM in Mississippi may require prevention strategies that are tailored to young black MSM and those in their sexual networks, and prevention interventions should be delivered in a manner to reach young black MSM throughout the state. Phylogenetic analysis can be a tool for local jurisdictions to understand the transmission dynamics in their areas. JF - AIDS AU - Oster, A M AU - Pieniazek, D AU - Zhang, X AU - Switzer, WM AU - Ziebell, R A AU - Mena, LA AU - Wei, X AU - Johnson, K L AU - Singh, S K AU - Thomas, P E AU - Elmore, KA AU - Heffelfinger, J D AD - 1600 Clifton Road NE, MS E-46, Atlanta, GA 30333, USA, AOster@cdc.gov Y1 - 2011 PY - 2011 DA - 2011 SP - 2157 EP - 2165 VL - 25 IS - 17 SN - 0269-9370, 0269-9370 KW - Risk Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - demography KW - local jurisdiction KW - Acquired immune deficiency syndrome KW - Infection KW - Disease transmission KW - Demography KW - Risk factors KW - Human immunodeficiency virus 1 KW - prevention KW - infection KW - Races KW - Ethnic groups KW - Phylogeny KW - Data processing KW - disease transmission KW - Human immunodeficiency virus KW - USA, Mississippi KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health KW - F 06910:Microorganisms & Parasites UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/907193859?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS&rft.atitle=Demographic+but+not+geographic+insularity+in+HIV+transmission+among+young+black+MSM&rft.au=Oster%2C+A+M%3BPieniazek%2C+D%3BZhang%2C+X%3BSwitzer%2C+WM%3BZiebell%2C+R+A%3BMena%2C+LA%3BWei%2C+X%3BJohnson%2C+K+L%3BSingh%2C+S+K%3BThomas%2C+P+E%3BElmore%2C+KA%3BHeffelfinger%2C+J+D&rft.aulast=Oster&rft.aufirst=A&rft.date=2011-01-01&rft.volume=25&rft.issue=17&rft.spage=2157&rft.isbn=&rft.btitle=&rft.title=AIDS&rft.issn=02699370&rft_id=info:doi/10.1097%2FQAD.0b013e32834bfde9 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Demography; Phylogeny; Data processing; Risk factors; Infection; Ethnic groups; Races; Disease transmission; demography; local jurisdiction; Acquired immune deficiency syndrome; disease transmission; Human immunodeficiency virus; infection; prevention; Human immunodeficiency virus 1; USA, Mississippi DO - http://dx.doi.org/10.1097/QAD.0b013e32834bfde9 ER - TY - JOUR T1 - Prevalence and risk behaviours for Chlamydia trachomatis and Neisseria gonorrhoeae infection among female sex workers in an HIV/AIDS high-risk area AN - 904469363; 14593007 AB - The objectives of this study were to estimate the prevalence of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infection among female sex workers (FSWs) in an HIV/AIDS high-risk area in China and to examine risk factors associated with CT or NG infection. A cross-sectional study of 568 FSWs was conducted in Kaiyuan City, Yunnan Province, PR China. The prevalence rates of HIV, CT and NG in the study participants were 11.1%, 17.4% and 8.3%, respectively. More than one-fifth (21.3%) of participants tested positive for either CT or NG. This study identifies a relatively high prevalence of CT or NG infection among FSWs in Kaiyuan. Notably, HIV infection was found to be associated with NG infection and study participants who tested positive for NG had a higher rate of CT infection. Further studies are warranted to examine the prevalence and spread of CT and NG in China, and their potential impact on the HIV epidemic. JF - International Journal of STD & AIDS AU - Jin, X AU - Chan, S AU - Ding, G AU - Wang, H AU - Xu, J AU - Wang, G AU - Chang, D AU - Reilly, K H AU - Wang, N AD - National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control & Prevention, Beijing Y1 - 2011 PY - 2011 DA - 2011 SP - 80 EP - 84 PB - Royal Society of Medicine Press Ltd., 1 Wimpole St. London W1M 8AE UK VL - 22 IS - 2 SN - 0956-4624, 0956-4624 KW - Microbiology Abstracts B: Bacteriology; Risk Abstracts; Virology & AIDS Abstracts KW - Acquired immune deficiency syndrome KW - Epidemics KW - Chlamydia trachomatis KW - Prostitution KW - Infection KW - Neisseria gonorrhoeae KW - China, People's Rep., Yunnan Prov. KW - Human immunodeficiency virus KW - Risk factors KW - infection KW - Risk groups KW - Females KW - sexually transmitted diseases KW - Urban areas KW - V 22360:AIDS and HIV KW - J 02400:Human Diseases KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/904469363?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+STD+%26+AIDS&rft.atitle=Prevalence+and+risk+behaviours+for+Chlamydia+trachomatis+and+Neisseria+gonorrhoeae+infection+among+female+sex+workers+in+an+HIV%2FAIDS+high-risk+area&rft.au=Jin%2C+X%3BChan%2C+S%3BDing%2C+G%3BWang%2C+H%3BXu%2C+J%3BWang%2C+G%3BChang%2C+D%3BReilly%2C+K+H%3BWang%2C+N&rft.aulast=Jin&rft.aufirst=X&rft.date=2011-01-01&rft.volume=22&rft.issue=2&rft.spage=80&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+STD+%26+AIDS&rft.issn=09564624&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Acquired immune deficiency syndrome; Epidemics; Risk factors; Risk groups; Prostitution; Infection; Human immunodeficiency virus; infection; Females; sexually transmitted diseases; Urban areas; Chlamydia trachomatis; Neisseria gonorrhoeae; China, People's Rep., Yunnan Prov. ER - TY - JOUR T1 - Time Course of Nicotine and Cotinine Incorporation into Samples of Nonsmokers' Beard Hair Following a Single Dose of Nicotine Polacrilex AN - 902345200; 15813580 AB - Hair nicotine and cotinine have been proposed as longer-term markers of exposure to secondhand smoke. In this study, we evaluated the rate and extent of nicotine and cotinine deposition into beard hair among six male nonsmokers following a single exposure to 4 mg of nicotine in Nicorette? (nicotine polacrilex) gum. We collected beard hair samples daily for 12 days following exposure and urine samples for 6 days after exposure. Using liquid chromatographic-tandem mass spectrometric analysis, we found that both nicotine and cotinine could be detected in beard samples within 24 h of the exposure and reached a maximum of about 71 pg nicotine and 47 pg cotinine/mg hair, respectively, within 1-2 days, followed by a gradual decline. Compared to beard hair concentrations, nicotine, cotinine, and hydroxycotinine were excreted in urine at much higher levels and also peaked on the day after exposure (mean ? SD urine cotinine = 300 ? 183 ng/mL). Our results confirmed that both nicotine and cotinine can be measured in beard hair samples following a single dose of nicotine. However, both the time-course and extent of deposition of these analytes in beard hair in this study differed from the results reported previously from a similar evaluation. JF - Journal of Analytical Toxicology AU - Bernert, John T AU - Alexander, Joseph R AU - Sosnoff, Connie S AU - McGuffey, James E AD - Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, Mailstop F-47, Atlanta, GA 30341, Jtb2@cdc.gov Y1 - 2011/01// PY - 2011 DA - Jan 2011 SP - 1 EP - 7 PB - Preston Publications, Inc., 6600 W. Touhy Ave. Niles IL 60714 United States VL - 35 IS - 1 SN - 0146-4760, 0146-4760 KW - Toxicology Abstracts KW - Smoke KW - Cotinine KW - Nicotine KW - Urine KW - Hair KW - X 24380:Social Poisons & Drug Abuse UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/902345200?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Analytical+Toxicology&rft.atitle=Time+Course+of+Nicotine+and+Cotinine+Incorporation+into+Samples+of+Nonsmokers%27+Beard+Hair+Following+a+Single+Dose+of+Nicotine+Polacrilex&rft.au=Bernert%2C+John+T%3BAlexander%2C+Joseph+R%3BSosnoff%2C+Connie+S%3BMcGuffey%2C+James+E&rft.aulast=Bernert&rft.aufirst=John&rft.date=2011-01-01&rft.volume=35&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Journal+of+Analytical+Toxicology&rft.issn=01464760&rft_id=info:doi/ L2 - http://www.ingentaconnect.com/content/pres/jat/2011/00000035/00000001/art00001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Smoke; Cotinine; Urine; Nicotine; Hair ER - TY - JOUR T1 - Design of Future Rabies Biologics and Antiviral Drugs AN - 896226784; 15119022 AB - In recent years, no major paradigm shifts have occurred in the utilization of new products for the prevention and control of rabies. Development of new cost-effective rabies biologics and antiviral drugs is critical in continuing to prevent and reduce disease. Current rabies vaccines are highly effective but have developed largely based on technical improvements in the vaccine industry. In the future, alternative approaches for improved vaccines, including novel avirulent rabies virus (RABV) vectors, should be pursued. Any rabies vaccine that is effective without the need for rabies immune globulin (RIG) will contribute fundamentally to disease prevention by reducing the cost and complexity of postexposure prophylaxis (PEP). The lack of high quality, affordable RIG is a continuing problem. Virus-specific monoclonal antibodies (mAbs) will soon fulfill the PEP requirement for passive immunity, currently met with RIG. Several relevant strategies for mAb production, including use of transgenic mice, humanization of mouse mAbs, and generation of human immune libraries, are underway. As a result of successful PEP and pre-exposure prophylaxis in developed countries, until recently, no significant focused efforts have been devoted to RABV-specific antiviral agents. To date, combination therapy including broad spectrum antiviral agents has been successful in only one case, and reports of antiviral activity are often conflicting. Current antiviral strategies target either the nucleoprotein or phosphoprotein, but drugs targeting the viral polymerase should be considered. Considering the lag from creation of new concepts to experimental development and clinical trials, many years will likely elapse between today's ideas and tomorrow's practices. JF - Advances in Imaging and Electron Physics AU - Smith, Todd G AU - Wu, Xianfu AU - Franka, Richard AU - Rupprecht, Charles E AD - Poxvirus and Rabies Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, tgsmith1@cdc.gov Y1 - 2011 PY - 2011 DA - 2011 SP - 345 EP - 363 PB - Academic Press VL - 79 SN - 1076-5670, 1076-5670 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Virology & AIDS Abstracts KW - Rabies virus KW - Rabies Vaccine KW - Antiviral drugs KW - Monoclonal antibodies KW - Postexposure prophylaxis KW - Drug delivery KW - Nucleoproteins KW - Drug development KW - Transgenic mice KW - Antiviral activity KW - Clinical trials KW - Immunity (passive) KW - Phosphoproteins KW - Antiviral agents KW - Rabies KW - Prophylaxis KW - Vaccines KW - Immunoglobulins KW - A 01340:Antibiotics & Antimicrobials KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/896226784?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Advances+in+Imaging+and+Electron+Physics&rft.atitle=Design+of+Future+Rabies+Biologics+and+Antiviral+Drugs&rft.au=Smith%2C+Todd+G%3BWu%2C+Xianfu%3BFranka%2C+Richard%3BRupprecht%2C+Charles+E&rft.aulast=Smith&rft.aufirst=Todd&rft.date=2011-01-01&rft.volume=79&rft.issue=&rft.spage=345&rft.isbn=&rft.btitle=&rft.title=Advances+in+Imaging+and+Electron+Physics&rft.issn=10765670&rft_id=info:doi/10.1016%2FB978-0-12-387040-7.00016-0 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Drug delivery; Monoclonal antibodies; Nucleoproteins; Drug development; Antiviral activity; Transgenic mice; Clinical trials; Immunity (passive); Antiviral agents; Phosphoproteins; Rabies; Prophylaxis; Vaccines; Immunoglobulins; Rabies virus DO - http://dx.doi.org/10.1016/B978-0-12-387040-7.00016-0 ER - TY - JOUR T1 - Potential immunotoxicological health effects following exposure to COREXIT 9500A during cleanup of the Deepwater Horizon oil spill. AN - 890671034; 21916747 AB - Workers involved in the Deepwater Horizon oil spill cleanup efforts reported acute pulmonary and dermatological adverse health effects. These studies were undertaken to assess the immunotoxicity of COREXIT 9500A, the primary dispersant used in cleanup efforts, as a potential causative agent. COREXIT 9500A and one of its active ingredients, dioctyl sodium sulfosuccinate (DSS), were evaluated using murine models for hypersensitivity and immune suppression, including the local lymph node assay (LLNA), phenotypic analysis of draining lymph node cells (DLN), mouse ear swelling test (MEST), total serum immunoglobulin E (IgE), and the plaque-forming cell (PFC) assay. Dermal exposure to COREXIT 9500A and DSS induced dose-responsive increases in dermal irritation and lymphocyte proliferation. The EC3 values for COREXIT 9500A and DSS were 0.4% and 3.9%, respectively, resulting in a classification of COREXIT 9500A as a potent sensitizer and DSS as a moderate sensitizer. A T-cell-mediated mechanism underlying the LLNA was supported by positive responses in the MEST assay for COREXIT and DSS, indicated by a significant increase in ear swelling 48 h post challenge. There were no marked alterations in total serum IgE or B220+/IgE+ lymph-node cell populations following exposure to COREXIT 9500A. Significant elevations in interferon (IFN)-γ but not interleukin (IL)-4 protein were also observed in stimulated lymph node cells. The absence of increases in IgE and IL-4 in the presence of enhanced lymphocyte proliferation, positive MEST responses, and elevations in IFN-γ suggest a T-cell-mediated mechanism. COREXIT 9500A did not induce immunosuppression in the murine model. JF - Journal of toxicology and environmental health. Part A AU - Anderson, Stacey E AU - Franko, Jennifer AU - Lukomska, Ewa AU - Meade, B J AD - National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA. Sanderson4@cdc.gov Y1 - 2011 PY - 2011 DA - 2011 SP - 1419 EP - 1430 VL - 74 IS - 21 SN - 1528-7394, 1528-7394 KW - Cytokines KW - 0 KW - Emulsifying Agents KW - Lipids KW - corexit 9500 KW - Dioctyl Sulfosuccinic Acid KW - 10041-19-7 KW - Immunoglobulin E KW - 37341-29-0 KW - Index Medicus KW - Immune Tolerance -- drug effects KW - Animals KW - Immunoglobulin E -- blood KW - Immunologic Tests KW - Dioctyl Sulfosuccinic Acid -- toxicity KW - Mice KW - Cytokines -- metabolism KW - Mice, Inbred BALB C KW - Lymphocytes -- drug effects KW - Lymph Nodes -- drug effects KW - Gulf of Mexico KW - Female KW - Environmental Restoration and Remediation -- adverse effects KW - Emulsifying Agents -- toxicity KW - Petroleum Pollution KW - Lipids -- toxicity KW - Immune System Phenomena -- drug effects KW - Hypersensitivity -- etiology KW - Environmental Exposure -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/890671034?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+toxicology+and+environmental+health.+Part+A&rft.atitle=Potential+immunotoxicological+health+effects+following+exposure+to+COREXIT+9500A+during+cleanup+of+the+Deepwater+Horizon+oil+spill.&rft.au=Anderson%2C+Stacey+E%3BFranko%2C+Jennifer%3BLukomska%2C+Ewa%3BMeade%2C+B+J&rft.aulast=Anderson&rft.aufirst=Stacey&rft.date=2011-01-01&rft.volume=74&rft.issue=21&rft.spage=1419&rft.isbn=&rft.btitle=&rft.title=Journal+of+toxicology+and+environmental+health.+Part+A&rft.issn=15287394&rft_id=info:doi/10.1080%2F15287394.2011.606797 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-11-21 N1 - Date created - 2011-09-15 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1080/15287394.2011.606797 ER - TY - JOUR T1 - Neurotoxicity following acute inhalation exposure to the oil dispersant COREXIT EC9500A. AN - 890671027; 21916746 AB - Consequent to the 2010 Deepwater Horizon oil spill in the Gulf of Mexico, there is an emergent concern about the short- and long-term adverse health effects of exposure to crude oil, weathered-oil products, and oil dispersants among the workforce employed to contain and clean up the spill. Oil dispersants typically comprise of a mixture of solvents and surfactants that break down floating oil to micrometer-sized droplets within the water column, thus preventing it from reaching the shorelines. As dispersants are generally sprayed from the air, workers are at risk for exposure primarily via inhalation. Such inhaled fractions might potentially permeate or translocate to the brain via olfactory or systemic circulation, producing central nervous system (CNS) abnormalities. To determine whether oil dispersants pose a neurological risk, male Sprague-Dawley rats were exposed by whole-body inhalation exposure to a model oil dispersant, COREXIT EC9500A (CE; approximately 27 mg/m(3) × 5 h/d × 1 d), and various molecular indices of neural dysfunction were evaluated in discrete brain areas, at 1 or 7 d postexposure. Exposure to CE produced partial loss of olfactory marker protein in the olfactory bulb. CE also reduced tyrosine hydroxylase protein content in the striatum. Further, CE altered the levels of various synaptic and neuronal intermediate filament proteins in specific brain areas. Reactive astrogliosis, as evidenced by increased expression of glial fibrillary acidic protein, was observed in the hippocampus and frontal cortex following exposure to CE. Collectively, these findings are suggestive of disruptions in olfactory signal transduction, axonal function, and synaptic vesicle fusion, events that potentially result in an imbalance in neurotransmitter signaling. Whether such acute molecular aberrations might persist and produce chronic neurological deficits remains to be ascertained. JF - Journal of toxicology and environmental health. Part A AU - Sriram, Krishnan AU - Lin, Gary X AU - Jefferson, Amy M AU - Goldsmith, William T AU - Jackson, Mark AU - McKinney, Walter AU - Frazer, David G AU - Robinson, Victor A AU - Castranova, Vincent AD - Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Toxicology and Molecular Biology Branch, Morgantown, West Virginia 26505, USA. kos4@cdc.gov Y1 - 2011 PY - 2011 DA - 2011 SP - 1405 EP - 1418 VL - 74 IS - 21 SN - 1528-7394, 1528-7394 KW - Emulsifying Agents KW - 0 KW - Glial Fibrillary Acidic Protein KW - Lipids KW - Olfactory Marker Protein KW - Omp protein, rat KW - corexit 9500 KW - Tyrosine 3-Monooxygenase KW - EC 1.14.16.2 KW - Index Medicus KW - Rats KW - Models, Animal KW - Animals KW - Rats, Sprague-Dawley KW - Petroleum Pollution KW - Toxicity Tests, Acute KW - Tyrosine 3-Monooxygenase -- biosynthesis KW - Glial Fibrillary Acidic Protein -- biosynthesis KW - Male KW - Olfactory Marker Protein -- biosynthesis KW - Environmental Restoration and Remediation -- adverse effects KW - Emulsifying Agents -- toxicity KW - Lipids -- toxicity KW - Brain -- drug effects KW - Brain -- metabolism KW - Inhalation Exposure -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/890671027?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+toxicology+and+environmental+health.+Part+A&rft.atitle=Neurotoxicity+following+acute+inhalation+exposure+to+the+oil+dispersant+COREXIT+EC9500A.&rft.au=Sriram%2C+Krishnan%3BLin%2C+Gary+X%3BJefferson%2C+Amy+M%3BGoldsmith%2C+William+T%3BJackson%2C+Mark%3BMcKinney%2C+Walter%3BFrazer%2C+David+G%3BRobinson%2C+Victor+A%3BCastranova%2C+Vincent&rft.aulast=Sriram&rft.aufirst=Krishnan&rft.date=2011-01-01&rft.volume=74&rft.issue=21&rft.spage=1405&rft.isbn=&rft.btitle=&rft.title=Journal+of+toxicology+and+environmental+health.+Part+A&rft.issn=15287394&rft_id=info:doi/10.1080%2F15287394.2011.606796 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-11-21 N1 - Date created - 2011-09-15 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1080/15287394.2011.606796 ER - TY - JOUR T1 - Understanding disparities in HIV infection between black and white MSM in the United States AN - 874192636; 14971642 AB - Objective: We evaluated several hypotheses for disparities in HIV infection between black and white MSM in the United States, including incarceration, partner HIV status, circumcision, sexual networks, and duration of infectiousness. Design: The 2008 National HIV Behavioral Surveillance System (NHBS), a cross-sectional survey conducted in 21 US cities. Methods: MSM were interviewed and tested for HIV infection. For MSM not previously diagnosed with HIV infection, we used logistic regression to test associations between newly diagnosed HIV infection and incarceration history, partner HIV status, circumcision status, and sexual networks (older partners, concurrency, and partner risk behaviors). For HIV-infected MSM, we assessed factors related to duration of infectiousness. Results: Among 5183 MSM not previously diagnosed with HIV infection, incarceration history, circumcision status, and sexual networks were not independently associated with HIV infection. Having HIV-infected partners [adjusted odds ratio (AOR) = 1.9, 95% confidence interval (CI) = 1.2-3.0] or partners of unknown status (AOR=1.4, CI = 1.1-1.7) were associated with HIV infection. Of these two factors, only one was more common among black MSM - having partners of unknown HIV status. Among previously diagnosed HIV-positive MSM, black MSM were less likely to be on antiretroviral therapy (ART). Conclusion: Less knowledge of partner HIV status and lower ART use among black MSM may partially explain differences in HIV infection between black and white MSM. Efforts to encourage discussions about HIV status between MSM and their partners and decrease barriers to ART provision among black MSM may decrease transmission. JF - AIDS AU - Oster, A M AU - Wiegand, R E AU - Sionean, C AU - Miles, I J AU - Thomas, P E AU - Melendez-Morales, L AU - Le, B C AU - Millett, G A AD - 1600 Clifton Rd NE, MS E-46, Atlanta, GA 30333, USA, AOster@cdc.gov Y1 - 2011 PY - 2011 DA - 2011 SP - 1103 EP - 1112 VL - 25 IS - 8 SN - 0269-9370, 0269-9370 KW - Risk Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - prisons KW - Historical account KW - USA KW - Acquired immune deficiency syndrome KW - Human immunodeficiency virus KW - antiretroviral agents KW - antiretroviral therapy KW - infection KW - Infection KW - Urban areas KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health KW - F 06910:Microorganisms & Parasites UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/874192636?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS&rft.atitle=Understanding+disparities+in+HIV+infection+between+black+and+white+MSM+in+the+United+States&rft.au=Oster%2C+A+M%3BWiegand%2C+R+E%3BSionean%2C+C%3BMiles%2C+I+J%3BThomas%2C+P+E%3BMelendez-Morales%2C+L%3BLe%2C+B+C%3BMillett%2C+G+A&rft.aulast=Oster&rft.aufirst=A&rft.date=2011-01-01&rft.volume=25&rft.issue=8&rft.spage=1103&rft.isbn=&rft.btitle=&rft.title=AIDS&rft.issn=02699370&rft_id=info:doi/10.1097%2FQAD.0b013e3283471efa LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-06-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - antiretroviral therapy; Infection; prisons; Historical account; Acquired immune deficiency syndrome; Human immunodeficiency virus; antiretroviral agents; infection; Urban areas; USA DO - http://dx.doi.org/10.1097/QAD.0b013e3283471efa ER - TY - JOUR T1 - HIV and Related Risk Behavior Among Men Who Have Sex with Men in Zanzibar, Tanzania: Results of a Behavioral Surveillance Survey AN - 872133100; 14229111 AB - We conducted a respondent driven sampling survey to estimate HIV prevalence and risk behavior among men who have sex with men (MSM) in Unguja, Zanzibar. Men aged greater than or equal to 15years living in Unguja and reporting anal sex with another man in the past 3months were asked to complete a questionnaire and provide specimens for biologic testing. HIV prevalence was 12.3% (95% confidence interval 8.7, 16.3). HIV infection was associated with injecting drugs in the past 3 months, Hepatitis C virus infection and being paid for sex in the past year. Interventions for MSM in Zanzibar are needed and should include linkages to prevention, care and treatment services. JF - AIDS and Behavior AU - Dahoma, Mohammed AU - Johnston, Lisa G AU - Holman, Abigail AU - Miller, Leigh Ann AU - Mussa, Mahmoud AU - Othman, Asha AU - Khatib, Ahmed AU - Issa, Ramadhan AU - Kendall, Carl AU - Kim, Andrea A AD - HHS-Centers for Disease Control and Prevention/Global AIDS Program, Atlanta, GA, USA, aakim@cdc.gov Y1 - 2011/01// PY - 2011 DA - Jan 2011 SP - 186 EP - 192 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 15 IS - 1 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Risk Abstracts KW - Inventories KW - Acquired immune deficiency syndrome KW - anal sex KW - homosexuality KW - Infection KW - Hepatitis KW - Hepatitis C virus KW - Behavior KW - Human immunodeficiency virus KW - intervention KW - infection KW - prevention KW - Sampling KW - Drugs KW - Sex KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/872133100?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=HIV+and+Related+Risk+Behavior+Among+Men+Who+Have+Sex+with+Men+in+Zanzibar%2C+Tanzania%3A+Results+of+a+Behavioral+Surveillance+Survey&rft.au=Dahoma%2C+Mohammed%3BJohnston%2C+Lisa+G%3BHolman%2C+Abigail%3BMiller%2C+Leigh+Ann%3BMussa%2C+Mahmoud%3BOthman%2C+Asha%3BKhatib%2C+Ahmed%3BIssa%2C+Ramadhan%3BKendall%2C+Carl%3BKim%2C+Andrea+A&rft.aulast=Dahoma&rft.aufirst=Mohammed&rft.date=2011-01-01&rft.volume=15&rft.issue=1&rft.spage=186&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-009-9646-7 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-06-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Inventories; anal sex; Sampling; Infection; Drugs; Sex; Hepatitis; Acquired immune deficiency syndrome; Behavior; Human immunodeficiency virus; intervention; prevention; homosexuality; infection; Hepatitis C virus DO - http://dx.doi.org/10.1007/s10461-009-9646-7 ER - TY - JOUR T1 - Multilaboratory Comparison of Streptococcus pneumoniae Opsonophagocytic Killing Assays and Their Level of Agreement for the Determination of Functional Antibody Activity in Human Reference Sera AN - 862792794; 14202620 AB - Antibody-mediated killing of Streptococcus pneumoniae (pneumococcus) by phagocytes is an important mechanism of protection of the human host against pneumococcal infections. Measurement of opsonophagocytic antibodies by use of a standardized opsonophagocytic assay (OPA) is important for the evaluation of candidate vaccines and required for the licensure of new pneumococcal conjugate vaccine formulations. We assessed agreement among six laboratories that used their own optimized OPAs on a panel of 16 human reference sera for 13 pneumococcal serotypes. Consensus titers, estimated using an analysis-of-variance (ANOVA) mixed-effects model, provided a common reference for assessing agreement among these laboratories. Agreement was evaluated in terms of assay accuracy, reproducibility, repeatability, precision, and bias. We also reviewed four acceptance criterion intervals for assessing the comparability of protocols when assaying the same reference sera. The precision, accuracy, and concordance results among laboratories and the consensus titers revealed acceptable agreement. The results of this study indicate that the bioassays evaluated in this study are robust, and the resultant OPA values are reproducible for the determination of functional antibody titers specific to 13 pneumococcal serotypes when performed by laboratories using highly standardized but not identical assays. The statistical methodologies employed in this study may serve as a template for evaluating future multilaboratory studies. JF - Clinical and Vaccine Immunology AU - Rose, Charles E AU - Romero-Steiner, Sandra AU - Burton, Robert L AU - Carlone, George M AU - Goldblatt, David AU - Nahm, Moon H AU - Ashton, Lindsey AU - Haston, Mitch AU - Ekstroem, Nina AU - Haikala, Raili AD - Department of Vaccination and Immune Protection, National Institute for Health and Welfare, Helsinki, Finland, CRose@cdc.gov Y1 - 2011/01// PY - 2011 DA - Jan 2011 SP - 135 EP - 142 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 18 IS - 1 SN - 1556-679X, 1556-679X KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Streptococcus pneumoniae KW - Antibodies KW - Serotypes KW - Statistics KW - Phagocytes KW - Reviews KW - Vaccines KW - Infection KW - Models KW - F 06905:Vaccines KW - J 02350:Immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/862792794?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+and+Vaccine+Immunology&rft.atitle=Multilaboratory+Comparison+of+Streptococcus+pneumoniae+Opsonophagocytic+Killing+Assays+and+Their+Level+of+Agreement+for+the+Determination+of+Functional+Antibody+Activity+in+Human+Reference+Sera&rft.au=Rose%2C+Charles+E%3BRomero-Steiner%2C+Sandra%3BBurton%2C+Robert+L%3BCarlone%2C+George+M%3BGoldblatt%2C+David%3BNahm%2C+Moon+H%3BAshton%2C+Lindsey%3BHaston%2C+Mitch%3BEkstroem%2C+Nina%3BHaikala%2C+Raili&rft.aulast=Rose&rft.aufirst=Charles&rft.date=2011-01-01&rft.volume=18&rft.issue=1&rft.spage=135&rft.isbn=&rft.btitle=&rft.title=Clinical+and+Vaccine+Immunology&rft.issn=1556679X&rft_id=info:doi/10.1128%2FCVI.00370-10 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-04-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Antibodies; Statistics; Serotypes; Phagocytes; Reviews; Vaccines; Infection; Models; Streptococcus pneumoniae DO - http://dx.doi.org/10.1128/CVI.00370-10 ER - TY - JOUR T1 - Evaluating the Protective Capacity of Two-Post ROPS for a Seat-Belted Occupant During a Farm Tractor Overturn AN - 856786244; 14408319 AB - This study evaluated the effectiveness of a commercial rollover protective structure (ROPS) and size-extended ROPS in protecting a 95th percentile male operator during tractor overturns. Six rear upset tests (commercial ROPS) and ten side upset tests (commercial and size-extended ROPS) were conducted. A 95th percentile instrumented male manikin was used in all tests. Head injury criterion (HIC sub(15)), 80 g limit on resultant head acceleration, neck injury criterion (N sub(ij)), and peak axial force (extension-compression) were employed to evaluate injury potential. In all rear tests, the manikin's head impact with the ground was within the tolerance limits for head/neck injuries. Based on limited trials in the side tests, the study observed a small to moderate chance of neck injuries under the commercial and size-extended ROPS conditions; the injury risk was not statistically significant between these two test conditions. This study identified a risk of non-fatal injuries for large-size operators in side overturns, although the prevention effectiveness of commercial versus size-extended ROPS cannot be determined without further testing. These findings may have implications for future ROPS designs. JF - Journal of Agricultural Safety and Health AU - Guan, J AU - Hsiao, H AU - Zwicner, J V AU - Current, R S AU - Lutz, T J AU - Cantis, D M AU - Powers, JR Jr AU - Newbraugh, B H AU - Spahr, J S AD - NIOSH Division of Safety Research, 1095 Willowdalc Road, MS G800, Morgantown, WV 26505, USA, czg6@cdc.gov Y1 - 2011/01// PY - 2011 DA - January 2011 SP - 15 EP - 32 VL - 17 IS - 1 SN - 1074-7583, 1074-7583 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Injuries KW - farms KW - neck injuries KW - prevention KW - head injuries KW - rollover KW - Agricultural equipment KW - H 2000:Transportation KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/856786244?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Agricultural+Safety+and+Health&rft.atitle=Evaluating+the+Protective+Capacity+of+Two-Post+ROPS+for+a+Seat-Belted+Occupant+During+a+Farm+Tractor+Overturn&rft.au=Guan%2C+J%3BHsiao%2C+H%3BZwicner%2C+J+V%3BCurrent%2C+R+S%3BLutz%2C+T+J%3BCantis%2C+D+M%3BPowers%2C+JR+Jr%3BNewbraugh%2C+B+H%3BSpahr%2C+J+S&rft.aulast=Guan&rft.aufirst=J&rft.date=2011-01-01&rft.volume=17&rft.issue=1&rft.spage=15&rft.isbn=&rft.btitle=&rft.title=Journal+of+Agricultural+Safety+and+Health&rft.issn=10747583&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-03-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Injuries; farms; head injuries; prevention; neck injuries; rollover; Agricultural equipment ER - TY - JOUR T1 - Impact of malnutrition on clinical presentation, clinical course, and mortality in MDR-TB patients AN - 856765194; 14030077 AB - Despite the adoption of strategies to prevent and treat multidrug-resistant tuberculosis (MDR-TB) over the past decade, Latvia continues to have one of the highest rates of MDR-TB in the world. It is important to identify modifiable factors that may impact on MDR-TB patient outcomes. A study was conducted to elucidate the association between nutritional status and clinical presentation, clinical course, and mortality in 995 adult patients treated for MDR-TB from 2000 to 2004. Twenty percent of patients were underweight, defined as a body mass index <18.5, at the time of diagnosis. These patients were significantly more likely to have clinical evidence of advanced disease, and had a greater risk of experiencing [egs]3 side-effects [adjusted odds ratio 1.5, 95% confidence interval (CI) 1.1-2.1] and death (adjusted hazard ratio 1.9, 95% CI 1.1-3.5) compared to patients who were normal or overweight. Interventions aimed at these high-risk patients, including nutritional supplementation as an adjunct to anti-TB therapy, should be considered and evaluated by TB programmes. JF - Epidemiology and Infection AU - Podewils, L J AU - Holtz, T AU - RIEKSTINA, V AU - SKRIPCONOKA, V AU - ZAROVSKA, E AU - KIRVELAITE, G AU - KREIGERE, E AU - LEIMANE, V AD - Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, GA, USA, lpp8@cdc.gov Y1 - 2011/01// PY - 2011 DA - Jan 2011 SP - 113 EP - 120 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU UK VL - 139 IS - 1 SN - 0950-2688, 0950-2688 KW - Risk Abstracts KW - tuberculosis KW - Mortality KW - Malnutrition KW - Mycobacterium KW - body mass KW - intervention KW - obesity KW - Latvia KW - Nutrition KW - Side effects KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/856765194?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Impact+of+malnutrition+on+clinical+presentation%2C+clinical+course%2C+and+mortality+in+MDR-TB+patients&rft.au=Podewils%2C+L+J%3BHoltz%2C+T%3BRIEKSTINA%2C+V%3BSKRIPCONOKA%2C+V%3BZAROVSKA%2C+E%3BKIRVELAITE%2C+G%3BKREIGERE%2C+E%3BLEIMANE%2C+V&rft.aulast=Podewils&rft.aufirst=L&rft.date=2011-01-01&rft.volume=139&rft.issue=1&rft.spage=113&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268810000907 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-03-01 N1 - Number of references - 13 N1 - Last updated - 2013-07-26 N1 - SubjectsTermNotLitGenreText - tuberculosis; Mortality; Malnutrition; body mass; intervention; obesity; Nutrition; Side effects; Mycobacterium; Latvia DO - http://dx.doi.org/10.1017/S0950268810000907 ER - TY - JOUR T1 - Pillar strength in underground stone mines in the United States AN - 855715685; 14259435 AB - Stone mines in the Eastern and Midwestern United States make use of the room-and-pillar method of mining to extract relatively flat-laying sedimentary formations. A survey of pillar performance was carried out to identify potential modes of instability. Pillars were found to have been successful in providing support to the overburden, but a small number of individual failed pillars were observed. Failure of the pillars was observed to be related to spalling of the hard brittle rocks, shearing along pre-existing angular discontinuities or progressive extrusion of soft infill materials on bedding planes. A method of estimating the pillar strength and selecting a safety factor for design was developed based on observations of stable and failed pillars, supplemented by numerical models. The developed pillar strength equation can be used to design stable stone mine pillars provided the rock conditions are similar to those included in the study. JF - International Journal of Rock Mechanics and Mining Sciences AU - Esterhuizen, G S AU - Dolinar AU - Ellenberger, J L AD - National Institute for Occupational Safety and Health, PO Box 18070, Pittsburgh, PA 15236, USA, eee5@cdc.gov Y1 - 2011/01// PY - 2011 DA - January 2011 SP - 42 EP - 50 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK VL - 48 IS - 1 SN - 1365-1609, 1365-1609 KW - Water Resources Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources KW - Pillar design KW - Pillar strength KW - Stone mines KW - Limestone KW - Room-and-pillar KW - Overburden KW - Mathematical models KW - Estimating KW - Safety KW - Failures KW - Surveys KW - Model Studies KW - Crystalline Rocks KW - USA KW - Strength KW - Rock Mechanics KW - Rock mechanics KW - Sedimentary structures KW - Spalling KW - Mining KW - Q2 09403:Chemicals from sea water KW - SW 0810:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/855715685?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Rock+Mechanics+and+Mining+Sciences&rft.atitle=Pillar+strength+in+underground+stone+mines+in+the+United+States&rft.au=Esterhuizen%2C+G+S%3BDolinar%3BEllenberger%2C+J+L&rft.aulast=Esterhuizen&rft.aufirst=G&rft.date=2011-01-01&rft.volume=48&rft.issue=1&rft.spage=42&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Rock+Mechanics+and+Mining+Sciences&rft.issn=13651609&rft_id=info:doi/10.1016%2Fj.ijrmms.2010.06.003 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-12-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Rock mechanics; Mathematical models; Sedimentary structures; Failures; Spalling; Mining; Crystalline Rocks; Rock Mechanics; Overburden; Strength; Estimating; Safety; Surveys; Model Studies; USA DO - http://dx.doi.org/10.1016/j.ijrmms.2010.06.003 ER - TY - JOUR T1 - Spatio-temporal patterns of road traffic noise pollution in Karachi, Pakistan AN - 853475161; 14041242 AB - We studied the spatial and temporal patterns of noise exposure due to road traffic in Karachi City, Pakistan, and found that levels of noise were generally higher during mornings and evenings because of the commuting pattern of Karachi residents. This study found the average value of noise levels to be over 66dB, which could cause serious annoyance according to the World Health Organization (WHO) outdoor noise guidelines. Maximum peak noise was over 101dB, which is close to 110dB, the level that can cause possible hearing impairment according to the WHO guidelines. We found that noise pollution is not an environmental problem reserved for developed countries, but occurs in developing countries as well. For this reason, steps might be required to reduce noise levels caused by road traffic. JF - Environment International AU - Mehdi, Mohammed Raza AU - Kim, Minho AU - Seong, Jeong Chang AU - Arsalan, Mudassar Hassan AD - NED University of Engineering & Technology, Karachi 75270, Pakistan (Post-doctoral Fellow at Department of Geosciences, University of West Georgia, Carrollton, Georgia, USA), htj0@cdc.gov Y1 - 2011/01// PY - 2011 DA - Jan 2011 SP - 97 EP - 104 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK VL - 37 IS - 1 SN - 0160-4120, 0160-4120 KW - Pollution Abstracts; Environment Abstracts KW - Spatio-temporal noise pattern KW - Road traffic noise pollution KW - Noise exposure KW - Noise and health KW - Karachi KW - traffic KW - Commuting KW - guidelines KW - Noise levels KW - Pakistan, Sindh, Karachi KW - Noise pollution KW - Hearing loss KW - Developing countries KW - developed countries KW - Urban areas KW - P 7000:NOISE KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/853475161?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environment+International&rft.atitle=Spatio-temporal+patterns+of+road+traffic+noise+pollution+in+Karachi%2C+Pakistan&rft.au=Mehdi%2C+Mohammed+Raza%3BKim%2C+Minho%3BSeong%2C+Jeong+Chang%3BArsalan%2C+Mudassar+Hassan&rft.aulast=Mehdi&rft.aufirst=Mohammed&rft.date=2011-01-01&rft.volume=37&rft.issue=1&rft.spage=97&rft.isbn=&rft.btitle=&rft.title=Environment+International&rft.issn=01604120&rft_id=info:doi/10.1016%2Fj.envint.2010.08.003 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-02-01 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - traffic; Commuting; guidelines; Noise levels; Hearing loss; Noise pollution; Developing countries; Urban areas; developed countries; Pakistan, Sindh, Karachi DO - http://dx.doi.org/10.1016/j.envint.2010.08.003 ER - TY - JOUR T1 - Utilization of dental care services among low-income HIV-positive persons receiving primary care in South Florida AN - 1706981145 AB - We investigated the use of dental care services among a population of low-income persons living with HIV/AIDS who had not seen a dental care provider during the 12 months prior to study enrollment. A total of 593 participants were recruited from five HIV primary care clinics in two South Florida counties and interviewed regarding past utilization of dental care services, HIV primary care service utilization, and barriers to care. Multivariate logistic regression analysis was used to determine correlates of oral care utilization within the preceding two years. One-third of respondents reported seeing a dentist in the preceding two years. The odds of having seen a dentist were greater for respondents with stable housing, more than a high school education, and who had received help in getting dental care; black respondents (compared to Hispanics and non-Hispanic whites) were less likely to have seen a dentist in the preceding two years. Despite the availability of dental services for low-income HIV-positive persons, utilization of dental care remains low. This study reinforces the need to provide assistance to HIV-positive persons in obtaining dental care. In particular, it indicates that such assistance should be targeted toward Black Americans, persons with low income and unstable housing situations, and those with limited help to navigate the health care system. JF - AIDS Care AU - Metsch, Lisa R AU - Tomar, Scott AU - Valverde, Eduardo AU - Jeanty, Yves AU - Messinger, Shari AU - Boza, Henry AD - Department of Epidemiology and Public Health, Miller School of Medicine, University of Miami, Miami ; Department of Community Dentistry and Behavioral Science, College of Dentistry, University of Florida, Gainesville, FL, USA ; Behavioral and Clinical Surveillance Branch, Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA ; Pereyra, Margaret; Department of Epidemiology and Public Health, Miller School of Medicine, University of Miami, Miami Y1 - 2011/01// PY - 2011 DA - Jan 2011 SP - 98 EP - 106 CY - London PB - Taylor & Francis Ltd. VL - 23 IS - 1 SN - 0954-0121 KW - Medical Sciences--Psychiatry And Neurology KW - Acquired Immune Deficiency Syndrome KW - Low income people KW - Oral hygiene KW - Primary health care KW - Service provision KW - Black Americans KW - Housing KW - Constraints KW - Clinics KW - Health Care Services KW - Hispanic Americans KW - Delivery Systems KW - Dental Care KW - Income KW - AIDS KW - Black American people KW - Dental care KW - Enrollment KW - Health care KW - Health professionals KW - Hispanic people KW - HIV KW - South Florida UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1706981145?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+Care&rft.atitle=Utilization+of+dental+care+services+among+low-income+HIV-positive+persons+receiving+primary+care+in+South+Florida&rft.au=Pereyra%2C+Margaret%3BMetsch%2C+Lisa+R%3BTomar%2C+Scott%3BValverde%2C+Eduardo%3BJeanty%2C+Yves%3BMessinger%2C+Shari%3BBoza%2C+Henry&rft.aulast=Pereyra&rft.aufirst=Margaret&rft.date=2011-01-01&rft.volume=23&rft.issue=1&rft.spage=98&rft.isbn=&rft.btitle=&rft.title=AIDS+Care&rft.issn=09540121&rft_id=info:doi/10.1080%2F09540121.2010.498861 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Name - South Florida N1 - Date revised - 2015-08-25 N1 - Last updated - 2016-05-16 N1 - SubjectsTermNotLitGenreText - South Florida DO - http://dx.doi.org/10.1080/09540121.2010.498861 ER - TY - JOUR T1 - Dual Resistance to Adamantanes and Oseltamivir Among Seasonal Influenza A(H1N1) Viruses: 2008-2010 AN - 1642622629; 21007038 AB - Two distinct genetic clades of seasonal influenza A(H1N1) viruses have cocirculated in the recent seasons: clade 2B oseltamivir-resistant and adamantane-susceptible viruses, and clade 2C viruses that are resistant to adamantanes and susceptible to oseltamivir. We tested seasonal influenza A(H1N1) viruses collected in 2008-2010 from the United States and globally for resistance to antivirals approved by the Food and Drug Administration. We report 28 viruses with both adamantane and oseltamivir (dual) resistance from 5 countries belonging to 4 distinct genotypes. Because of limited options for antiviral treatment, emergence of dual-resistant influenza viruses poses a public health concern, and their circulation needs to be closely monitored. JF - Journal of Infectious Diseases AU - Sheu, Tiffany G AU - Fry, Alicia M AU - Garten, Rebecca J AU - Deyde, Varough M AU - Shwe, Thein AU - Bullion, Lesley AU - Peebles, Patrick J AU - LI, Yan AU - Klimov, Alexander I AU - Gubareva, Larisa V AD - Influenza Division, Centers for Disease Control and Prevention; Battelle Memorial Institute, Atlanta, Georgia, lgubareva@cdc.gov Y1 - 2011/01/01/ PY - 2011 DA - 2011 Jan 01 SP - 13 EP - 17 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 203 IS - 1 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Viruses KW - Genotypes KW - Oseltamivir KW - Public health KW - Influenza KW - USA KW - Sulfur dioxide KW - Infectious diseases KW - Antiviral agents KW - Seasonal variations KW - Drugs KW - H 12000:Epidemiology and Public Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1642622629?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Dual+Resistance+to+Adamantanes+and+Oseltamivir+Among+Seasonal+Influenza+A%28H1N1%29+Viruses%3A+2008-2010&rft.au=Sheu%2C+Tiffany+G%3BFry%2C+Alicia+M%3BGarten%2C+Rebecca+J%3BDeyde%2C+Varough+M%3BShwe%2C+Thein%3BBullion%2C+Lesley%3BPeebles%2C+Patrick+J%3BLI%2C+Yan%3BKlimov%2C+Alexander+I%3BGubareva%2C+Larisa+V&rft.aulast=Sheu&rft.aufirst=Tiffany&rft.date=2011-01-01&rft.volume=203&rft.issue=1&rft.spage=13&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiq005 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Influenza; Antiviral agents; Genotypes; Public health; Oseltamivir; Sulfur dioxide; Infectious diseases; Viruses; Drugs; Seasonal variations; USA DO - http://dx.doi.org/10.1093/infdis/jiq005 ER - TY - JOUR T1 - Why Behavioral And Environmental Interventions Are Needed To Improve Health At Lower Cost AN - 1032898855; 14811727 AB - We used a dynamic simulation model of the US health system to test three proposed strategies to reduce deaths and improve the cost-effectiveness of interventions: expanding health insurance coverage, delivering better preventive and chronic care, and protecting health by enabling healthier behavior and improving environmental conditions. We found that each alone could save lives and provide good economic value, but they are likely to be more effective in combination. Although coverage and care save lives quickly, they tend to increase costs. The impact of protection grows more gradually, but it is a critical ingredient over time for lowering both the number of deaths and reducing costs. Only protection slows the growth in the prevalence of disease and injury and thereby alleviates rather than exacerbates demand on limited primary care capacity. When added to a simulated scenario with coverage and care, protection could save 90 percent more lives and reduce costs by 30 percent in year 10; by year 25, that same investment in protection could save about 140 percent more lives and reduce costs by 62 percent. JF - Health Affairs AU - Milstein, Bobby AU - Homer, Jack AU - Briss, Peter AU - Burton, Deron AU - Pechacek, Terry AD - Bobby Milstein is the coordinator for the Syndemics Prevention Network at the Centers for Disease Control and Prevention, in Atlanta, Georgia. Jack Homer is president of Homer Consulting, in Voorhees, New Jersey. Peter Briss is the medical director of the National Center for Chronic Disease Prevention and Health Promotion, at the Centers for Disease Control and Prevention. Deron Burton is a Commissioned Corps officer at the Center for Global Health, at the Centers for Disease Control and Prevention. Terry Pechacek is the associate director for science of the Office on Smoking and Health, at the Centers for Disease Control and Prevention., bmilstein@cdc.gov Y1 - 2011 PY - 2011 DA - 2011 SP - 823 EP - 832 PB - Project Hope, 7500 Old Georgetown Rd. Suite 600 Bethesda MD 20814-6133 USA VL - 30 IS - 5 SN - 0278-2715, 0278-2715 KW - Health & Safety Science Abstracts KW - Cost benefit analysis KW - Economics KW - Environmental conditions KW - Injuries KW - Insurance KW - Intervention KW - Mortality KW - Simulation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1032898855?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+Affairs&rft.atitle=Why+Behavioral+And+Environmental+Interventions+Are+Needed+To+Improve+Health+At+Lower+Cost&rft.au=Milstein%2C+Bobby%3BHomer%2C+Jack%3BBriss%2C+Peter%3BBurton%2C+Deron%3BPechacek%2C+Terry&rft.aulast=Milstein&rft.aufirst=Bobby&rft.date=2011-01-01&rft.volume=30&rft.issue=5&rft.spage=823&rft.isbn=&rft.btitle=&rft.title=Health+Affairs&rft.issn=02782715&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-08-01 N1 - Last updated - 2012-09-24 N1 - SubjectsTermNotLitGenreText - Mortality; Injuries; Economics; Simulation; Intervention; Environmental conditions; Insurance; Cost benefit analysis ER - TY - JOUR T1 - Design and Analysis of Cognitive Interviews for Comparative Multinational Testing AN - 1030869598; 201228063 AB - This article summarizes the work of the Comparative Cognitive Testing Workgroup, an international coalition of survey methodologists interested in developing an evidence-based methodology for examining the comparability of survey questions within cross-cultural or multinational contexts. To meet this objective, it was necessary to ensure that the cognitive interviewing (CI) method itself did not introduce method bias. Therefore, the workgroup first identified specific characteristics inherent in CI methodology that could undermine the comparability of CI evidence. The group then developed and implemented a protocol addressing those issues. In total, 135 cognitive interviews were conducted by participating countries. Through the process, the group identified various interpretive patterns resulting from sociocultural and language-related differences among countries as well as other patterns of error that would impede comparability of survey data. [Reprinted by permission of Sage Publications Inc., copyright holder.] JF - Field Methods AU - Miller, Kristen AU - Fitzgerald, Rory AU - Padilla, Jose-Luis AU - Willson, Stephanie AU - Widdop, Sally AU - Caspar, Rachel AU - Dimov, Martin AU - Gray, Michelle AU - Nunes, Catia AU - Prufer, Peter AU - Schobi, Nicole AU - Schoua-Glusberg, Alisu AD - National Center for Health Statistics, Hyattsville, MD, USA ksmiller@cdc.gov Y1 - 2011///0, PY - 2011 DA - 0, 2011 SP - 379 EP - 396 PB - Sage Publications, Thousand Oaks CA VL - 23 IS - 4 SN - 1525-822X, 1525-822X KW - cognitive interviewing comparability question evaluation cross-cultural questionnaire design KW - Sociocultural Factors KW - Evidence Based Practice KW - Coalitions KW - Interviews KW - Bias KW - Crosscultural Differences KW - Cognition KW - article KW - 0514: culture and social structure; social anthropology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1030869598?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocabs&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Field+Methods&rft.atitle=Design+and+Analysis+of+Cognitive+Interviews+for+Comparative+Multinational+Testing&rft.au=Miller%2C+Kristen%3BFitzgerald%2C+Rory%3BPadilla%2C+Jose-Luis%3BWillson%2C+Stephanie%3BWiddop%2C+Sally%3BCaspar%2C+Rachel%3BDimov%2C+Martin%3BGray%2C+Michelle%3BNunes%2C+Catia%3BPrufer%2C+Peter%3BSchobi%2C+Nicole%3BSchoua-Glusberg%2C+Alisu&rft.aulast=Miller&rft.aufirst=Kristen&rft.date=2011-01-01&rft.volume=23&rft.issue=4&rft.spage=379&rft.isbn=&rft.btitle=&rft.title=Field+Methods&rft.issn=1525822X&rft_id=info:doi/10.1177%2F1525822X11414802 LA - English DB - Sociological Abstracts N1 - Date revised - 2012-08-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Cognition; Crosscultural Differences; Interviews; Sociocultural Factors; Evidence Based Practice; Bias; Coalitions DO - http://dx.doi.org/10.1177/1525822X11414802 ER - TY - JOUR T1 - Improved detection of botulinum neurotoxin type A in stool by mass spectrometry AN - 1022560253; 14602995 AB - Botulinum neurotoxins (BoNTs) are the most toxic substances known to humankind. Rapid and sensitive detection of BoNTs is necessary for timely clinical confirmation of the disease state in botulism. BoNTs cleave proteins and peptide mimics at specific sites. A mass spectrometry (MS)-based method, Endopep-MS, can detect these cleavages and has detection limits of 0.05-0.5 mouse LD sub(50 (U) in serum, depending on the BoNT serotypes. In this method, the products generated from cleavage of peptide substrates using antibody affinity-purified toxins are detected by MS. Nonspecific bound endogenous proteases or peptidases in stool can coextract with the toxin, cleaving the peptide substrates and reducing the sensitivity of the method. Here we report a method to reduce nonspecific substrate cleavage by reducing stool protease coextraction in the Endopep-MS assay.) JF - Analytical Biochemistry AU - Wang, Dongxia AU - Baudys, Jakub AU - Kalb, Suzanne R AU - Barr, John R AD - National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA, jbarr@cdc.gov PY - 2011 SP - 67 EP - 73 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 412 IS - 1 SN - 0003-2697, 0003-2697 KW - Toxicology Abstracts; CSA Neurosciences Abstracts KW - Botulinum neurotoxin KW - Detection KW - Mass spectrometry KW - Stool KW - Antibodies KW - Serotypes KW - Botulism KW - Proteinase KW - Clostridium botulinum KW - Botulinum toxin KW - Feces KW - peptidase KW - Mass spectroscopy KW - N3 11008:Neurochemistry KW - X 24320:Food Additives & Contaminants UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1022560253?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytical+Biochemistry&rft.atitle=Improved+detection+of+botulinum+neurotoxin+type+A+in+stool+by+mass+spectrometry&rft.au=Wang%2C+Dongxia%3BBaudys%2C+Jakub%3BKalb%2C+Suzanne+R%3BBarr%2C+John+R&rft.aulast=Wang&rft.aufirst=Dongxia&rft.date=2011-01-01&rft.volume=412&rft.issue=1&rft.spage=67&rft.isbn=&rft.btitle=&rft.title=Analytical+Biochemistry&rft.issn=00032697&rft_id=info:doi/10.1016%2Fj.ab.2011.01.025 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-06-01 N1 - Last updated - 2016-01-06 N1 - SubjectsTermNotLitGenreText - Antibodies; Serotypes; Botulism; Proteinase; Botulinum toxin; Feces; peptidase; Mass spectroscopy; Clostridium botulinum DO - http://dx.doi.org/10.1016/j.ab.2011.01.025 ER - TY - JOUR T1 - Group Differences in Risk Across Three Domains Using an Expanded Measure of Sexual Orientation AN - 954597361; 14245132 AB - The purpose of this study was to highlight associations between sexual orientation and risk outcomes in late adolescence and early adulthood using an expanded measure of sexual orientation. Recent data indicate higher levels of risk behavior in a newly identified population, mostly heterosexuals, as compared to heterosexuals. Comparisons among groups using an expanded measure of sexual orientation such as this, however, often do not include all possible groups or may restrict comparisons between groups. Data were derived from the National Longitudinal Study of Adolescent Health (Add Health); participants identified as heterosexual, mostly heterosexual, bisexual, mostly gay, or gay. Main risk outcomes were parental mistreatment, home displacement, thoughts of suicide, depressive symptoms, frequency of drinking, and delinquency. A priori planned comparisons examined differences between: (a) heterosexual vs. mostly heterosexual, (b) gay vs. mostly gay, (c) mostly heterosexual vs. bisexual, (d) mostly gay vs. bisexual, (e) mostly heterosexual vs. mostly gay, (f) heterosexual vs. gay, (g) heterosexual vs. bisexual, and (h) gay vs. bisexual. Mostly heterosexual youth were at significantly greater risk than heterosexual youth on all outcomes but did not differ from bisexual or mostly gay youth. Heterosexuals were at lower risk as compared to mostly heterosexuals and bisexuals. This study provides further evidence of differential risk associations for sexual minorities. JF - Journal of Primary Prevention AU - Loosier, Penny S AU - Dittus, Patricia J AD - Division of STD Prevention, Centers for Disease Control and Prevention, 1600 Clifton Rd, Mailstop E-44, Atlanta, GA, 30333, USA, ploosier@cdc.gov Y1 - 2010/12// PY - 2010 DA - Dec 2010 SP - 261 EP - 272 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 31 IS - 5-6 SN - 0278-095X, 0278-095X KW - Risk Abstracts KW - bisexuality KW - depression KW - delinquency KW - prevention KW - Adolescents KW - longitudinal studies KW - suicide KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/954597361?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Primary+Prevention&rft.atitle=Group+Differences+in+Risk+Across+Three+Domains+Using+an+Expanded+Measure+of+Sexual+Orientation&rft.au=Loosier%2C+Penny+S%3BDittus%2C+Patricia+J&rft.aulast=Loosier&rft.aufirst=Penny&rft.date=2010-12-01&rft.volume=31&rft.issue=5-6&rft.spage=261&rft.isbn=&rft.btitle=&rft.title=Journal+of+Primary+Prevention&rft.issn=0278095X&rft_id=info:doi/10.1007%2Fs10935-010-0228-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2012-03-30 N1 - SubjectsTermNotLitGenreText - delinquency; prevention; bisexuality; depression; suicide; longitudinal studies; Adolescents DO - http://dx.doi.org/10.1007/s10935-010-0228-2 ER - TY - JOUR T1 - What does occupation represent as an indicator of socioeconomic status?: Exploring occupational prestige and health AN - 904469053; 14205199 AB - The association between socioeconomic status (SES) and health has been widely documented. However, the role of occupation in this association is not clear because occupation is less often used than income and education as an indicator of SES, especially in the United States. This may be caused by the ambiguity in what occupation represents: both health-enhancing resources (e.g., self-affirmation) and health-damaging hazards (e.g., job stress). SES has two aspects: resources and status. While income and education represent resources and imply status, occupational prestige is an explicit indicator of the social status afforded by one's occupation. Using data from the US General Social Survey in 2002 and 2006 (n = 3151), we examine whether occupational prestige has a significant association with self-rated health independent from other SES indicators (income, education), occupational categories (e.g., managerial, professional, technical, service), and previously established work-related health determinants (job strain, work place social support, job satisfaction). After all covariates were included in the multiple logistic regression model, higher occupational prestige was associated with lower odds of reporting poor/fair self-rated health. We discuss potential mechanisms through which occupational prestige may impact health. Our findings not only suggest multiple ways that occupation is associated with health, but also highlight the utility of occupational prestige as an SES indicator that explicitly represents social standing. JF - Social Science and Medicine AU - Fujishiro, Kaori AU - Xu, Jun AU - Gong, Fang AD - Division of Surveillance, Hazard Evaluation, and Field Studies, National Institute for Occupational Safety and Health, 4676 Columbia Parkway (R-15), Cincinnati, Ohio 45226, United States, kfujishiro@cdc.gov Y1 - 2010/12// PY - 2010 DA - Dec 2010 SP - 2100 EP - 2107 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 71 IS - 12 SN - 0277-9536, 0277-9536 KW - Health & Safety Science Abstracts KW - USA KW - Education KW - social class KW - income KW - Socioeconomics KW - Occupational health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/904469053?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Social+Science+and+Medicine&rft.atitle=What+does+occupation+represent+as+an+indicator+of+socioeconomic+status%3F%3A+Exploring+occupational+prestige+and+health&rft.au=Fujishiro%2C+Kaori%3BXu%2C+Jun%3BGong%2C+Fang&rft.aulast=Fujishiro&rft.aufirst=Kaori&rft.date=2010-12-01&rft.volume=71&rft.issue=12&rft.spage=2100&rft.isbn=&rft.btitle=&rft.title=Social+Science+and+Medicine&rft.issn=02779536&rft_id=info:doi/10.1016%2Fj.socscimed.2010.09.026 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Education; social class; income; Socioeconomics; Occupational health; USA DO - http://dx.doi.org/10.1016/j.socscimed.2010.09.026 ER - TY - JOUR T1 - Cigarette Smoking Women of Reproductive Age Who Use Oral Contraceptives: Results from the 2002 and 2004 Behavioral Risk Factor Surveillance Systems AN - 899133116; 13994536 AB - Despite health warnings about the increased risk of cerebrovascular disease among women who smoke while using oral contraceptives (OCs), prior research suggests that OC use is still prevalent among women who smoke cigarettes. Our objective was to investigate the prevalence of OC use among cigarette smoking women of reproductive age in the United States. Study Design: We extracted data from the 2002 and 2004 Behavioral Risk Factor Surveillance System surveys of 76,544 women between 18 and 44 years of age who reported using some form of contraception. OC use, or self-reported use of "the pill," was examined among those who currently smoke, either everyday or some days. Multivariable logistic regression models were used to compare OC use between smoking and nonsmoking women. Results: One fourth (26.9%) of U.S. women who smoke compared with 34.6% of nonsmoking women reported currently using OCs. After adjusting for age, race/ethnicity, marital status, education level, binge drinking, and health care coverage, women who smoke were 0.6 (95% confidence interval [CI], 0.6-0.7) times as likely to use OCs as nonsmoking women. Among women aged 35 to 44 years, the odds of OC use among smokers was even further reduced (odds ratio [OR], 0.3; 95% CI, 0.3-0.4) compared with nonsmokers. Conclusion: Among U.S. women of reproductive age who use contraception, particularly among women aged 35 to 44 years, those who smoke cigarettes are significantly less likely to use OCs than those who do not. JF - Women's Health Issues AU - McClave, Annette K AU - Hogue, Carol J AU - Huber, Larissa RBrunner AU - Ehrlich, Alexandra C AD - Office on Smoking and Health, Centers for Disease Control and Prevention, Atlanta, Georgia, AMcClave@cdc.gov Y1 - 2010/12// PY - 2010 DA - Dec 2010 SP - 380 EP - 385 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 20 IS - 6 SN - 1049-3867, 1049-3867 KW - Toxicology Abstracts; Risk Abstracts KW - Drinking KW - Age KW - Data processing KW - Cerebrovascular diseases KW - marriage KW - Contraceptives (oral) KW - binge drinking KW - contraceptives KW - Models KW - Smoke KW - USA KW - Education KW - Health care KW - Contraception KW - Risk factors KW - Cigarette smoking KW - Regression analysis KW - Females KW - Races KW - Ethnic groups KW - X 24380:Social Poisons & Drug Abuse KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/899133116?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Women%27s+Health+Issues&rft.atitle=Cigarette+Smoking+Women+of+Reproductive+Age+Who+Use+Oral+Contraceptives%3A+Results+from+the+2002+and+2004+Behavioral+Risk+Factor+Surveillance+Systems&rft.au=McClave%2C+Annette+K%3BHogue%2C+Carol+J%3BHuber%2C+Larissa+RBrunner%3BEhrlich%2C+Alexandra+C&rft.aulast=McClave&rft.aufirst=Annette&rft.date=2010-12-01&rft.volume=20&rft.issue=6&rft.spage=380&rft.isbn=&rft.btitle=&rft.title=Women%27s+Health+Issues&rft.issn=10493867&rft_id=info:doi/10.1016%2Fj.whi.2010.06.006 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - Drinking; Age; Data processing; Cerebrovascular diseases; Contraceptives (oral); Models; Smoke; Contraception; Risk factors; Cigarette smoking; Regression analysis; Ethnic groups; Races; Education; Health care; Females; marriage; binge drinking; contraceptives; USA DO - http://dx.doi.org/10.1016/j.whi.2010.06.006 ER - TY - JOUR T1 - Co-feeding as a route for transmission of Rickettsia conorii israelensis between Rhipicephalus sanguineus ticks AN - 888097322; 14238679 AB - Rickettsia conorii is widely distributed in Europe, Asia, and Africa. The brown dog tick, Rhipicephalus sanguineus, is the recognized vector of R. conorii. In this study, we assessed the efficiency of R. conorii israelensis transmission between co-feeding Rh. sanguineus ticks. Infected Rh. sanguineus adults and uninfected nymphs were fed simultaneously upon either naieve dogs or a dog previously exposed to this agent. When ticks were placed upon naieve dogs, 92-100% of nymphs acquired the infection and 80-88% of infected engorged nymphs transmitted it transstadially. When ticks were placed upon a seropositive dog, only 8-28.5% of recipient nymphs became infected. Our results establish the first evidence for efficient natural transmission of R. conorii israelensis between co-feeding ticks upon both naieve and seropositive dogs. This route of transmission can ensure continuous circulation of R. conorii israelensis in tick vectors even in the absence of naieve reservoir hosts. JF - Experimental and Applied Acarology AU - Zemtsova, G AU - Killmaster, L F AU - Mumcuoglu, KY AU - Levin, M L AD - Rickettsial Zoonoses Branch, Mail Stop G-13, National Center for Zoonotic, Vector-Borne and Enteric Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA, 30333, USA, MLevin@cdc.gov Y1 - 2010/12// PY - 2010 DA - Dec 2010 SP - 383 EP - 392 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 52 IS - 4 SN - 0168-8162, 0168-8162 KW - Microbiology Abstracts B: Bacteriology; Entomology Abstracts KW - Ixodidae KW - Rickettsia conorii KW - Vectors KW - Rhipicephalus sanguineus KW - Infection KW - Disease transmission KW - J 02410:Animal Diseases KW - Z 05350:Medical, Veterinary, and Agricultural Entomology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/888097322?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Experimental+and+Applied+Acarology&rft.atitle=Co-feeding+as+a+route+for+transmission+of+Rickettsia+conorii+israelensis+between+Rhipicephalus+sanguineus+ticks&rft.au=Zemtsova%2C+G%3BKillmaster%2C+L+F%3BMumcuoglu%2C+KY%3BLevin%2C+M+L&rft.aulast=Zemtsova&rft.aufirst=G&rft.date=2010-12-01&rft.volume=52&rft.issue=4&rft.spage=383&rft.isbn=&rft.btitle=&rft.title=Experimental+and+Applied+Acarology&rft.issn=01688162&rft_id=info:doi/10.1007%2Fs10493-010-9375-7 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-09-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Vectors; Infection; Disease transmission; Ixodidae; Rickettsia conorii; Rhipicephalus sanguineus DO - http://dx.doi.org/10.1007/s10493-010-9375-7 ER - TY - JOUR T1 - Occupational Distribution of Persons With Confirmed 2009 H1N1 Influenza AN - 874182450; 14292380 AB - Objective: To assess the distribution of illness by industry sector and occupation reflected in early 2009 H1N1 influenza surveillance. Methods: We analyzed data reported for April to July 2009, for 1361 laboratory-confirmed 2009 H1N1 influenza-infected persons 16 years or older, with work status information from four states. A North American Industry Classification System 2007 code was assigned to each employed person. For a subset, an occupation code was assigned. Results: Of 898 employed individuals, 611 (68.0%) worked in the non-health care sector. The largest proportions worked in public administration, educational services, and accommodation and food services. In Wisconsin health care personnel, 53.6% were paraprofessionals, 33.6% professionals, and 12.7% other workers; 26.9% worked in ambulatory settings, 46.2% in hospitals, and 26.9% in nursing or residential care facilities. Conclusions: Our findings suggest that industry sectors and occupations should be explored systematically in future influenza surveillance. JF - Journal of Occupational and Environmental Medicine AU - Suarthana, E AU - Laney, A S AU - Kreiss, K AU - Anderson, HA AU - Hunt, D C AU - Neises, D AU - Goodin, K AU - Thomas, A AU - Vandermeer, M AU - Storey, E AD - National Institute for Occupational Safety and Health, 1095 Willowdale Rd, Room 2806, Morgantown, WV 26505, USA, ESuarthana@cdc.gov Y1 - 2010/12// PY - 2010 DA - Dec 2010 SP - 1212 EP - 1216 VL - 52 IS - 12 SN - 1076-2752, 1076-2752 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts; Toxicology Abstracts KW - Classification KW - Classification systems KW - Data processing KW - Food KW - Health care KW - Hospitals KW - Influenza KW - Medical personnel KW - Nursing KW - Personnel KW - influenza KW - USA, Wisconsin KW - H 1000:Occupational Safety and Health KW - X 24350:Industrial Chemicals KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/874182450?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Occupational+Distribution+of+Persons+With+Confirmed+2009+H1N1+Influenza&rft.au=Suarthana%2C+E%3BLaney%2C+A+S%3BKreiss%2C+K%3BAnderson%2C+HA%3BHunt%2C+D+C%3BNeises%2C+D%3BGoodin%2C+K%3BThomas%2C+A%3BVandermeer%2C+M%3BStorey%2C+E&rft.aulast=Suarthana&rft.aufirst=E&rft.date=2010-12-01&rft.volume=52&rft.issue=12&rft.spage=1212&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e3181fd32e4 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-06-01 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - Classification systems; Influenza; Data processing; Personnel; Nursing; Food; Medical personnel; Hospitals; Health care; Classification; influenza; USA, Wisconsin DO - http://dx.doi.org/10.1097/JOM.0b013e3181fd32e4 ER - TY - JOUR T1 - Heat illness among high school athletes - United States, 2005-2009 AN - 847440788; 14185253 AB - Heat illness is a leading cause of death and disability among U.S. high school athletes. Methods: To examine the incidence and characteristics of heat illness among high school athletes, CDC analyzed data from the National High School Sports-Related Injury Surveillance Study for the period 2005-2009. Results: During 2005-2009, the 100 schools sampled reported a total of 118 heat illnesses among high school athletes resulting in >= 1 day of time lost from athletic activity, a rate of 1.6 per 100,000 athlete-exposures, and an average of 29.5 time-loss heat illnesses per school year. The average corresponds to a weighted average annual estimate of 9,237 illnesses nationwide. The highest rate of time-loss heat illness was among football players, 4.5 per 100,000 athlete-exposures, a rate 10 times higher than the average rate (0.4) for the eight other sports. Time-loss heat illnesses occurred most frequently during August (66.3%) and while practicing or playing football (70.7%). No deaths were reported. Conclusions: Consistent with guidelines from the National Athletic Trainers' Association, to reduce the risk for heat illness, high school athletic programs should implement heat-acclimatization guidelines (e.g., set limits on summer practice duration and intensity). All athletes, coaches, athletic trainers, and parents/guardians should be aware of the risk factors for heat illness, follow recommended strategies, and be prepared to respond quickly to symptoms of illness. Coaches also should continue to stress to their athletes the importance of maintaining proper hydration before, during, and after sports activities. Impact of industry: By implementing preventive recommendations and quickly recognizing and responding to heat illness, coaches, athletic trainers, and the sporting community can prevent future deaths. JF - Journal of Safety Research AU - Yard, Ellen E AU - Gilchrist, Julie AU - Haileyesus, Tadesse AU - Murphy, Matthew AU - Collins, Christy AU - McIlvain, Natalie AU - Comstock, RDawn AD - Health Studies Branch, Division of Environmental Hazards and Health Effects, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, United States, eyard@cdc.gov Y1 - 2010/12// PY - 2010 DA - Dec 2010 SP - 471 EP - 474 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK VL - 41 IS - 6 SN - 0022-4375, 0022-4375 KW - Physical Education Index; Risk Abstracts; Health & Safety Science Abstracts KW - heat tolerance KW - Death KW - disabilities KW - Summer KW - Risk reduction KW - sports related injuries KW - risk reduction KW - Interscholastic sports KW - schools KW - guidelines KW - Disabilities KW - Mortality KW - Guidelines KW - Heat tolerance KW - Athletic trainers KW - Illness KW - athletes KW - Summer programs KW - USA KW - Schools KW - Coaches KW - Heat KW - summer KW - Athletes (interscholastic) KW - Athletes KW - H 11000:Diseases/Injuries/Trauma KW - PE 090:Sports Medicine & Exercise Sport Science KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/847440788?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Safety+Research&rft.atitle=Heat+illness+among+high+school+athletes+-+United+States%2C+2005-2009&rft.au=Yard%2C+Ellen+E%3BGilchrist%2C+Julie%3BHaileyesus%2C+Tadesse%3BMurphy%2C+Matthew%3BCollins%2C+Christy%3BMcIlvain%2C+Natalie%3BComstock%2C+RDawn&rft.aulast=Yard&rft.aufirst=Ellen&rft.date=2010-12-01&rft.volume=41&rft.issue=6&rft.spage=471&rft.isbn=&rft.btitle=&rft.title=Journal+of+Safety+Research&rft.issn=00224375&rft_id=info:doi/10.1016%2Fj.jsr.2010.09.001 LA - English DB - Physical Education Index; ProQuest Environmental Science Collection N1 - Date revised - 2011-01-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Summer programs; Interscholastic sports; Death; Coaches; Heat; Athletic trainers; Illness; Athletes; Athletes (interscholastic); heat tolerance; Mortality; disabilities; Guidelines; Heat tolerance; Summer; Risk reduction; sports related injuries; athletes; risk reduction; Schools; schools; guidelines; Disabilities; summer; USA DO - http://dx.doi.org/10.1016/j.jsr.2010.09.001 ER - TY - JOUR T1 - Reduced Azithromycin Susceptibility in Shigella sonnei, United States AN - 847439721; 14222143 AB - To investigate azithromycin susceptibility in Shigella sonnei in the United States, we examined the azithromycin minimum inhibitory concentrations (MICs) of outbreak and routine human S. sonnei isolates. Isolate susceptibility clustered at 8mg/L, but three isolates displayed higher MICs (>64mg/L) to azithromycin. All three isolates contained a plasmid-encoded mphA gene, known to encode a macrolide-2'-phosphotransferase enzyme. Transformation of the mphA gene into Escherichia coli DH10B allowed the transfer of decreased susceptibility to azithromycin. Although these isolates might traditionally be defined as resistant, there are no established breakpoints for resistance to confirm that treatment of these isolates with azithromycin would fail, which complicates susceptibility screening. JF - Microbial Drug Resistance AU - Howie, R L AU - Folster, J P AU - Bowen, A AU - Barzilay, E J AU - Whichard, J M AD - Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Atlanta, GA 30329, USA, gux8@cdc.gov Y1 - 2010/12// PY - 2010 DA - Dec 2010 SP - 245 EP - 248 VL - 16 IS - 4 SN - 1076-6294, 1076-6294 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology KW - Transformation KW - Breakpoints KW - Shigella sonnei KW - Azithromycin KW - Drug resistance KW - Escherichia coli KW - Enzymes KW - Minimum inhibitory concentration KW - A 01350:Microbial Resistance KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/847439721?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Microbial+Drug+Resistance&rft.atitle=Reduced+Azithromycin+Susceptibility+in+Shigella+sonnei%2C+United+States&rft.au=Howie%2C+R+L%3BFolster%2C+J+P%3BBowen%2C+A%3BBarzilay%2C+E+J%3BWhichard%2C+J+M&rft.aulast=Howie&rft.aufirst=R&rft.date=2010-12-01&rft.volume=16&rft.issue=4&rft.spage=245&rft.isbn=&rft.btitle=&rft.title=Microbial+Drug+Resistance&rft.issn=10766294&rft_id=info:doi/10.1089%2Fmdr.2010.0028 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Transformation; Breakpoints; Drug resistance; Azithromycin; Enzymes; Minimum inhibitory concentration; Shigella sonnei; Escherichia coli DO - http://dx.doi.org/10.1089/mdr.2010.0028 ER - TY - JOUR T1 - CHECKING THE FOUNDATION: RECENT RADIOBIOLOGY AND THE LINEAR NO-THRESHOLD THEORY AN - 839707225; 14092160 AB - The linear no-threshold (LNT) theory has been adopted as the foundation of radiation protection standards and risk estimation for several decades. The "microdosimetric argument" has been offered in support of the LNT theory. This argument postulates that energy is deposited in critical cellular targets by radiation in a linear fashion across all doses down to zero, and that this in turn implies a linear relationship between dose and biological effect across all doses. This paper examines whether the microdosimetric argument holds at the lowest levels of biological organization following low dose, low dose-rate exposures to ionizing radiation. The assumptions of the microdosimetric argument are evaluated in light of recent radiobiological studies on radiation damage in biological molecules and cellular and tissue level responses to radiation damage. There is strong evidence that radiation initially deposits energy in biological molecules (e.g., DNA) in a linear fashion, and that this energy deposition results in various forms of prompt DNA damage that may be produced in a pattern that is distinct from endogenous (e.g., oxidative) damage. However, a large and rapidly growing body of radiobiological evidence indicates that cell and tissue level responses to this damage, particularly at low doses and/or dose-rates, are nonlinear and may exhibit thresholds. To the extent that responses observed at lower levels of biological organization in vitro are predictive of carcinogenesis observed in vivo, this evidence directly contradicts the assumptions upon which the microdosimetric argument is based. JF - Health Physics AU - Ulsh, BA AD - National Institute for Occupational Safety and Health, 4676 Columbia Parkway, Mailstop C-46, Cincinnati, OH 45226, USA, bau6@cdc.gov Y1 - 2010/12// PY - 2010 DA - Dec 2010 SP - 747 EP - 758 PB - Williams & Wilkins, 351 W. Camden St. Baltimore MD 21201 United States VL - 99 IS - 6 SN - 0017-9078, 0017-9078 KW - Risk Abstracts KW - biological effects KW - Ionizing radiation KW - Carcinogenesis KW - DNA KW - R2 23020:Technological risks UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839707225?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+Physics&rft.atitle=CHECKING+THE+FOUNDATION%3A+RECENT+RADIOBIOLOGY+AND+THE+LINEAR+NO-THRESHOLD+THEORY&rft.au=Ulsh%2C+BA&rft.aulast=Ulsh&rft.aufirst=BA&rft.date=2010-12-01&rft.volume=99&rft.issue=6&rft.spage=747&rft.isbn=&rft.btitle=&rft.title=Health+Physics&rft.issn=00179078&rft_id=info:doi/10.1097%2FHP.0b013e3181e32477 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-01 N1 - Last updated - 2015-08-05 N1 - SubjectsTermNotLitGenreText - biological effects; Ionizing radiation; Carcinogenesis; DNA DO - http://dx.doi.org/10.1097/HP.0b013e3181e32477 ER - TY - JOUR T1 - The potential impact of light emitting diode lighting on reducing mining injuries during operation and maintenance of lighting systems AN - 760216739; 13667980 AB - Research by the US National Institute for Occupational Safety and Health (NIOSH) indicates that light emitting diodes (LEDs) can be used to enhance safety by improving a miner's ability to see mining hazards and reducing glare. This paper investigates if LEDs provide another benefit by reducing miner exposure to hazards during maintenance and operation of LED lighting. LEDs could provide useful lives up to 50 times longer than incandescent lighting commonly used in mining and could enable design changes to reduce certain hazards. The mining accident records compiled by the Mine Safety and Health Administration (MSHA) were examined to determine the extent and nature of accidents involving the maintenance and operation of mine luminaries. A total of 140 relevant accident records were found for the years 2002-2006. These incidents resulted in 3668days lost from work with an additional 925days of restricted activity. The injury narratives were studied to determine if the implementation of LED-based luminaries could reduce injury severity and frequency. The greatest near-term potential impacts appear to be related to reducing maintenance and cap lamp redesign. Longer term (5years), low-power and lightweight auxiliary LED lighting for surface mines could also have potential impact for improving safety. JF - Safety Science AU - Yenchek, Michael R AU - Sammarco, John J AD - National Institute for Occupational Safety and Health, Pittsburgh Research Laboratory, P.O. Box 18070, 626 Cochrans Mill Road, Pittsburgh, PA 15236, USA, mby5@cdc.gov Y1 - 2010/12// PY - 2010 DA - Dec 2010 SP - 1380 EP - 1386 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 48 IS - 10 SN - 0925-7535, 0925-7535 KW - Health & Safety Science Abstracts KW - Illumination KW - Light emitting diode KW - Safety KW - Mining KW - Accidents KW - safety engineering KW - Safety regulations KW - Injuries KW - Occupational safety KW - Lighting KW - Mines KW - Maintenance KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/760216739?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Safety+Science&rft.atitle=The+potential+impact+of+light+emitting+diode+lighting+on+reducing+mining+injuries+during+operation+and+maintenance+of+lighting+systems&rft.au=Yenchek%2C+Michael+R%3BSammarco%2C+John+J&rft.aulast=Yenchek&rft.aufirst=Michael&rft.date=2010-12-01&rft.volume=48&rft.issue=10&rft.spage=1380&rft.isbn=&rft.btitle=&rft.title=Safety+Science&rft.issn=09257535&rft_id=info:doi/10.1016%2Fj.ssci.2010.05.011 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-05-01 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Accidents; Safety regulations; safety engineering; Injuries; Occupational safety; Lighting; Mining; Mines; Maintenance DO - http://dx.doi.org/10.1016/j.ssci.2010.05.011 ER - TY - JOUR T1 - Interpreting Screening Questionnaires Specific Respiratory Symptoms and Their Relationship to Objective Test Results AN - 1020835896; 14292382 AB - Objective: To better delineate the relationship between responses to screening respiratory symptom questionnaires and various pulmonary function test results. Methods: Spirometry, methacholine challenge, standardized questionnaires, smoking, medical, and work histories were recorded at initial and 5-year follow-up surveys among 411 participants. Percent-predicted forced expiratory volume in 1 second (ppFEV sub(1)), 5-year FEV sub(1) decline, and proportion of methacholine responders (% hyper-responders) were compared with questionnaire responses utilizing generalized estimating equations modeling and analysis of variance. Results: Significant associations were found between ppFEV sub(1) and cough, phlegm, dyspnea, or ever wheezing; between greater percentage of hyper-responders and dyspnea with wheezing, ever/persistent wheezing, or history of asthma/hay fever; and between accelerated FEV sub(1) decline and new onset dyspnea with wheezing, phlegm, or persistent wheeze. Conclusions: Particular respiratory symptoms reported on screening questionnaires are associated with specific physiologic abnormalities, enhancing questionnaire utility in workplace health surveillance. JF - Journal of Occupational and Environmental Medicine AU - Petsonk, EL AU - Wang, M L AD - NIOSH, Mail Stop H-G900.2, 1095 Willowdale Road, Morgantown, WV 26505, USA, elp2@cdc.gov Y1 - 2010/12// PY - 2010 DA - Dec 2010 SP - 1225 EP - 1229 VL - 52 IS - 12 SN - 1076-2752, 1076-2752 KW - Health & Safety Science Abstracts KW - Asthma KW - Historical account KW - Respiratory diseases KW - Respiratory function KW - Smoking KW - Standards KW - hay fever KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1020835896?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Interpreting+Screening+Questionnaires+Specific+Respiratory+Symptoms+and+Their+Relationship+to+Objective+Test+Results&rft.au=Petsonk%2C+EL%3BWang%2C+M+L&rft.aulast=Petsonk&rft.aufirst=EL&rft.date=2010-12-01&rft.volume=52&rft.issue=12&rft.spage=1225&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e3181fd728f LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-06-01 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - Smoking; Historical account; hay fever; Asthma; Standards; Respiratory function; Respiratory diseases DO - http://dx.doi.org/10.1097/JOM.0b013e3181fd728f ER - TY - JOUR T1 - Exposure to flour dust and sensitization among bakery employees AN - 1017966700; 16691605 AB - Background The National Institute for Occupational Safety and Health conducted a study to determine prevalences of sensitization to bakery-associated antigens (BAAs) and work-related respiratory symptoms at a large commercial bakery. Methods The following measurements were carried out: personal breathing zone (PBZ) and general area (GA) monitoring for inhalable flour dust, -amylase and wheat, a questionnaire, and blood tests for IgE specific to flour dust, wheat, -amylase, and common aeroallergens. Results Of 186 bakery employees present during our site visit, 161completed the questionnaire and 96 allowed their blood to be drawn. The geometric mean PBZ and GA inhalable flour dust concentrations for the lower-exposure group was 0.235 mg/m3, and for the higher-exposure group was 3.01 mg/m3. Employees in the higher-exposure group had significantly higher prevalences of work-related wheezing, runny nose, stuffy nose, and frequent sneezing than the lower-exposure group. The prevalence of IgE specific to wheat was significantly higher among employees who ever had a job in the higher-exposure group or in production at another bakery at both the >= 0.10 kU/L and the >= 0.35 kU/L cutoffs, and to flour dust and -amylase at the >= 0.10 kU/L cutoff, compared to the lower-exposure group. Conclusions Despite knowledge of the risks of exposure to flour being available for centuries, U.S. employees are still at risk of sensitization and respiratory symptoms from exposure to high levels of BAA. Am. J. Ind. Med. 53:1225-1232, 2010. ? 2010 Wiley-Liss, Inc. JF - American Journal of Industrial Medicine AU - Page, Elena H AU - Dowell Cih, Chad H AU - Mueller, Charles A AU - Biagini, Raymond E AU - Heederik, Dick AD - Division of Surveillance, Hazard Evaluations and Field Studies, National Institute for Occupational Safety and Health, Cincinnati, Ohio, epage@cdc.gov Y1 - 2010/12// PY - 2010 DA - Dec 2010 SP - 1225 EP - 1232 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 53 IS - 12 SN - 1097-0274, 1097-0274 KW - Toxicology Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - wheat KW - Inhalation KW - Inventories KW - Respiration KW - Occupational safety KW - Wheezing KW - Dust KW - Triticum aestivum KW - Blood KW - USA KW - Immunoglobulin E KW - Allergens KW - Nose KW - Flour KW - R2 23080:Industrial and labor KW - H 1000:Occupational Safety and Health KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1017966700?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Exposure+to+flour+dust+and+sensitization+among+bakery+employees&rft.au=Page%2C+Elena+H%3BDowell+Cih%2C+Chad+H%3BMueller%2C+Charles+A%3BBiagini%2C+Raymond+E%3BHeederik%2C+Dick&rft.aulast=Page&rft.aufirst=Elena&rft.date=2010-12-01&rft.volume=53&rft.issue=12&rft.spage=1225&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=10970274&rft_id=info:doi/10.1002%2Fajim.20893 L2 - http://onlinelibrary.wiley.com/doi/10.1002/ajim.20893/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2013-11-15 N1 - SubjectsTermNotLitGenreText - Inventories; Blood; Respiration; Allergens; Immunoglobulin E; Wheezing; Nose; Flour; Dust; Inhalation; wheat; Occupational safety; Triticum aestivum; USA DO - http://dx.doi.org/10.1002/ajim.20893 ER - TY - JOUR T1 - Development of a transplantation transmission sentinel network to improve safety and traceability of organ and tissues AN - 954609789; 14166980 AB - The US lags behind other developed countries in creating a system to monitor disease transmission and other complications from human allograft use, despite a pressing need. The risks of transmission are amplified in transplantation, since at least 8 organs and more than 100 tissues can be recovered from a single common organ and tissue donor. Moreover, since many allografts collected in the US are distributed internationally, tissue safety is a global concern. In June 2005, participants of a US government-sponsored workshop concluded that a communication network for the tracking and reporting of disease transmissions for tissues and organs was critically needed. The United Network for Organ Sharing (UNOS) entered into a cooperative agreement with the Centers for Disease Control and Prevention (CDC) in 2006 to develop a system prototype. Over the following 3years, the Transplantation Transmission Sentinel Network (TTSN) was developed and piloted with the participation of organ procurement organizations, tissue banks and transplant centers. The prototype centered around three elements of data entry: (1) donation, (2) tissue implantation, and (3) adverse event. The pilot proved that a system can be built and operated successfully, but also suggested that users may be hesitant to report adverse events. CDC has requested further input on scope and cost to build a transplant surveillance infrastructure for a fully functional national system. For tissues however, in contrast to organs, tracking from recovery to implantation will be necessary before a system is operable, requiring common identifiers and nomenclature. Until a US sentinel network is operational, future transmission events that are preventable may result nationally and globally due to its absence. JF - Cell and Tissue Banking AU - Strong, DMichael AU - Seem, Debbie AU - Taylor, Gloria AU - Parker, Jory AU - Stewart, Darren AU - Kuehnert, Matthew J AD - Office of Blood, Organ and other Tissue Safety, Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention (CDC), 1600 Clifton Road, Mailstop A-07, Atlanta, GA, 30333, USA, mkuehnert@cdc.gov Y1 - 2010/11// PY - 2010 DA - Nov 2010 SP - 335 EP - 343 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 11 IS - 4 SN - 1389-9333, 1389-9333 KW - Biotechnology and Bioengineering Abstracts KW - Nomenclature KW - Donors KW - Data processing KW - Conferences KW - Disease control KW - Communication KW - Disease transmission KW - W 30920:Tissue Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/954609789?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cell+and+Tissue+Banking&rft.atitle=Development+of+a+transplantation+transmission+sentinel+network+to+improve+safety+and+traceability+of+organ+and+tissues&rft.au=Strong%2C+DMichael%3BSeem%2C+Debbie%3BTaylor%2C+Gloria%3BParker%2C+Jory%3BStewart%2C+Darren%3BKuehnert%2C+Matthew+J&rft.aulast=Strong&rft.aufirst=DMichael&rft.date=2010-11-01&rft.volume=11&rft.issue=4&rft.spage=335&rft.isbn=&rft.btitle=&rft.title=Cell+and+Tissue+Banking&rft.issn=13899333&rft_id=info:doi/10.1007%2Fs10561-010-9198-0 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2012-03-30 N1 - SubjectsTermNotLitGenreText - Nomenclature; Donors; Data processing; Conferences; Communication; Disease control; Disease transmission DO - http://dx.doi.org/10.1007/s10561-010-9198-0 ER - TY - JOUR T1 - Concentration of metals in blood of Maine children 1-6 years old AN - 954606231; 14164371 AB - Blood lead concentrations are higher in young children than in other age groups, whereas little is known regarding concentrations of other metals in young children. We measured the concentrations of a suite of metals in the blood of children 1-6 years of age, and assessed potential differences by age, season, or region of Maine. We used blood submitted to the Maine State Health and Environmental Testing Laboratory for blood lead analysis to determine the concentrations of arsenic (As), antimony (Sb), cadmium (Cd), manganese (Mn), mercury (Hg), selenium (Se), tin (Sn), and uranium (U) in 1350 children 1-6 years of age. The essential metals Mn and Se were detected in all samples, and As and Sb were detected in >90% of samples. Hg was detected in approximately 60% of samples. U and Cd were less often detected in blood samples, at approximately 30% and 10% of samples, respectively. Sn was not detected in any sample. Concentrations of As, Hg, and Se increased with age, whereas Sb decreased with age. Concentrations also varied by season and region for some though not all metals. Significant pairwise correlations were observed for a number of metals. Blood is a reasonable compartment for measurement of most of these metals in young children. The use of convenience samples provided a cost-effective mechanism for assessing exposure of young children in Maine. JF - Journal of Exposure Science and Environmental Epidemiology AU - Rice, Deborah C AU - Lincoln, Rebecca AU - Martha, John AU - Parker, Lisa AU - Pote, Kenneth AU - Xing, Shuqin AU - Smith, Andrew E AD - Department of Health and Human Services, Environmental and Occupational Health Programs, Maine Center for Disease Control, Augusta, Maine, USA Y1 - 2010/11// PY - 2010 DA - Nov 2010 SP - 634 EP - 643 PB - Nature Publishing Group, The Macmillan Building London N1 9XW UK VL - 20 IS - 7 SN - 1559-0631, 1559-0631 KW - Toxicology Abstracts; Pollution Abstracts KW - Age KW - Heavy metals KW - Lead KW - Selenium KW - Uranium KW - Economics KW - Cadmium KW - Manganese KW - Metals KW - Arsenic KW - Children KW - Blood levels KW - Antimony KW - Mercury KW - USA, Maine KW - Tin KW - X 24390:Radioactive Materials KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/954606231?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Exposure+Science+and+Environmental+Epidemiology&rft.atitle=Concentration+of+metals+in+blood+of+Maine+children+1-6+years+old&rft.au=Rice%2C+Deborah+C%3BLincoln%2C+Rebecca%3BMartha%2C+John%3BParker%2C+Lisa%3BPote%2C+Kenneth%3BXing%2C+Shuqin%3BSmith%2C+Andrew+E&rft.aulast=Rice&rft.aufirst=Deborah&rft.date=2010-11-01&rft.volume=20&rft.issue=7&rft.spage=634&rft.isbn=&rft.btitle=&rft.title=Journal+of+Exposure+Science+and+Environmental+Epidemiology&rft.issn=15590631&rft_id=info:doi/10.1038%2Fjes.2010.42 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2012-03-30 N1 - SubjectsTermNotLitGenreText - Selenium; Arsenic; Age; Heavy metals; Uranium; Antimony; Mercury; Cadmium; Tin; Children; Manganese; Lead; Metals; Economics; Blood levels; USA, Maine DO - http://dx.doi.org/10.1038/jes.2010.42 ER - TY - JOUR T1 - Exploring the associations between intimate partner violence and women's mental health: Evidence from a population-based study in Paraguay AN - 954592581; 13947261 AB - Using a nationally representative sample from the 2008 Paraguayan National Survey of Demography and Sexual and Reproductive Health, we examine the association between emotional, physical, and sexual intimate partner violence (IPV) and mental health among women aged 15-44 years who have ever been married or in a consensual union. The results from multivariate logistic regression models demonstrate that controlling for women's socioeconomic and marital status and history of childhood abuse and their male partners' unemployment and alcohol consumption, IPV is independently associated with an increased risk for common mental disorders (CMD) and suicidal ideation measured by the Self Reporting Questionnaire (SRQ-20). IPV variables substantially improve the explanatory power of the models, particularly for suicidal ideation. Emotional abuse, regardless of when it occurred, is associated with the greatest increased risk for CMD whereas recent physical abuse is associated with the greatest increased risk for suicidal ideation. These findings suggest that efforts to identify women with mental health problems, particularly suicidal ideation, should include screening for the types and history of IPV victimization. JF - Social Science and Medicine AU - Ishida, Kanako AU - Stupp, Paul AU - Melian, Mercedes AU - Serbanescu, Florina AU - Goodwin, Mary AD - Division of Reproductive Health, Centers for Disease Control and Prevention, 4770 Buford Hwy, NE Mail stop K-23, Atlanta, GA 30341, USA, kishida@cdc.gov Y1 - 2010/11// PY - 2010 DA - Nov 2010 SP - 1653 EP - 1661 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 71 IS - 9 SN - 0277-9536, 0277-9536 KW - Risk Abstracts KW - demography KW - Historical account KW - Alcohol KW - unemployment KW - Paraguay KW - domestic violence KW - Reproduction KW - Females KW - marriage KW - suicide KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/954592581?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Social+Science+and+Medicine&rft.atitle=Exploring+the+associations+between+intimate+partner+violence+and+women%27s+mental+health%3A+Evidence+from+a+population-based+study+in+Paraguay&rft.au=Ishida%2C+Kanako%3BStupp%2C+Paul%3BMelian%2C+Mercedes%3BSerbanescu%2C+Florina%3BGoodwin%2C+Mary&rft.aulast=Ishida&rft.aufirst=Kanako&rft.date=2010-11-01&rft.volume=71&rft.issue=9&rft.spage=1653&rft.isbn=&rft.btitle=&rft.title=Social+Science+and+Medicine&rft.issn=02779536&rft_id=info:doi/10.1016%2Fj.socscimed.2010.08.007 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - demography; Alcohol; Historical account; unemployment; domestic violence; Reproduction; Females; marriage; suicide; Paraguay DO - http://dx.doi.org/10.1016/j.socscimed.2010.08.007 ER - TY - JOUR T1 - Measurement of multiple drugs in urine, water, and on surfaces using fluorescence covalent microbead immunosorbent assay AN - 874193062; 14972706 AB - There are a range of applications that require the measurement of multiple drugs such as urine analysis, drug determination in water, and screening for drug contamination on surfaces. Some of the procedures used such as enzyme-linked immunosorbent assay (ELISA) are simple but can only determine one drug at a time, and others such as GC-MS or LC-MS are complex, time-consuming, and expensive. In this study, fluorescence covalent microbead immunosorbent assay (FCMIA) was investigated as a simple method for the measurement of multiple drugs simultaneously in three matrices: diluted urine, water, and on surfaces. Five different drugs of abuse or their metabolites (methamphetamine, caffeine, benzoylecgonine (a metabolite of cocaine), tetrahydrocannabinol (THC), the active ingredient in marijuana, and oxycodone) were studied over the range 0-15 ng/ml. There was no measureable cross-reactivity among the drugs at the concentrations studied. Urine dilutions from 1/50 to 1/2.5 were studied and dilutions less than 1/20 had a significant effect on the methamphetamine assay but limited effects on the benzoylecgonine and oxycodone assays and almost no effect on the THC assay. For assays performed in 1/20 urine dilution, water, and diluted surface sampling buffer, least detectable doses (LDD) were 1 ng/ml or less for the drugs. Surfaces spiked with drugs were sampled with swabs wetted with surface sampling buffer and recoveries were linear over the range 0-100 ng/100 cm super(2) surface loading for all drugs. FCMIA has potential to be used for the measurement of multiple drugs in the matrices studied. JF - Toxicology Mechanisms and Methods AU - Smith, J AU - Sammons, D AU - Robertson, S AU - Biagini, R AU - Snawder, J AD - Biomonitoring Research Team, Biomonitoring and Health Assessment Branch, National Institute for Occupational Safety and Health, Cincinnati, Ohio, USA, jps3@cdc.gov Y1 - 2010/11// PY - 2010 DA - Nov 2010 SP - 587 EP - 593 VL - 20 IS - 9 SN - 1537-6516, 1537-6516 KW - Environment Abstracts; Toxicology Abstracts KW - Cross-reactivity KW - Contamination KW - Surface water KW - buffers KW - Metabolites KW - oxycodone KW - Drug abuse KW - Drug screening KW - Immunosorbents KW - Cannabis KW - Caffeine KW - Sampling KW - Cocaine KW - Drugs KW - methamphetamine KW - Enzyme-linked immunosorbent assay KW - Fluorescence KW - cocaine KW - Tetrahydrocannabinol KW - Methamphetamine KW - Urine KW - microspheres KW - Immunoassays KW - X 24380:Social Poisons & Drug Abuse KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/874193062?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+Mechanisms+and+Methods&rft.atitle=Measurement+of+multiple+drugs+in+urine%2C+water%2C+and+on+surfaces+using+fluorescence+covalent+microbead+immunosorbent+assay&rft.au=Smith%2C+J%3BSammons%2C+D%3BRobertson%2C+S%3BBiagini%2C+R%3BSnawder%2C+J&rft.aulast=Smith&rft.aufirst=J&rft.date=2010-11-01&rft.volume=20&rft.issue=9&rft.spage=587&rft.isbn=&rft.btitle=&rft.title=Toxicology+Mechanisms+and+Methods&rft.issn=15376516&rft_id=info:doi/10.3109%2F15376516.2010.518172 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-06-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Enzyme-linked immunosorbent assay; Fluorescence; Cross-reactivity; Contamination; Metabolites; Drug screening; Drug abuse; oxycodone; Immunosorbents; Tetrahydrocannabinol; Methamphetamine; Urine; microspheres; Cannabis; Caffeine; Sampling; Cocaine; Surface water; cocaine; buffers; Immunoassays; Drugs; methamphetamine DO - http://dx.doi.org/10.3109/15376516.2010.518172 ER - TY - JOUR T1 - Challenges in assessing nanomaterial toxicology: a personal perspective AN - 869579795; 14821173 AB - Nanotechnology exploits the fact that nanoparticles exhibit unique physicochemical properties, which are distinct from fine-sized particles of the same composition. It follows that nanoparticles may also express distinct bioactivity and unique interactions with biological systems. Therefore, it is essential to assess the potential health risks of exposure to nanoparticles to allow development and implementation of prevention measures. Risk assessment requires data concerning hazard and exposure. Several challenges face the field of nanotoxicology in obtaining the necessary data for assessment of the bioactivity of nanoparticles. They include: (1) the vast number of nanoparticle types to be evaluated, (2) the need to use nanoparticle doses and structure sizes in cellular and animal test systems which are relevant to anticipated workplace exposures, and (3) artifactual in vitro results due to absorption of nutrients or assay indicator compounds from the culture media. This 'opinion' reviews the progress made in the field of nanotoxicology in recent years to overcome these challenges. WIREs Nanomed Nanobiotechnol 2010 2 569-577 JF - Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology AU - Geraci, Charles L AU - Castranova, Vincent AD - Education and Information Division, National Institute for Occupational Safety and Health, Cincinnati, OH, USA, Ciu9@cdc.gov Y1 - 2010/11/01/ PY - 2010 DA - 2010 Nov 01 SP - 569 EP - 577 PB - John Wiley & Sons, Ltd., Baffins Lane Chichester W. Sussex PO19 1UD UK VL - 2 IS - 6 SN - 1939-0041, 1939-0041 KW - Toxicology Abstracts; Biotechnology and Bioengineering Abstracts KW - Risk assessment KW - Data processing KW - Physicochemical properties KW - Nutrients KW - nanoparticles KW - Media (culture) KW - nanotechnology KW - W 30910:Imaging KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/869579795?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Wiley+Interdisciplinary+Reviews%3A+Nanomedicine+and+Nanobiotechnology&rft.atitle=Challenges+in+assessing+nanomaterial+toxicology%3A+a+personal+perspective&rft.au=Geraci%2C+Charles+L%3BCastranova%2C+Vincent&rft.aulast=Geraci&rft.aufirst=Charles&rft.date=2010-11-01&rft.volume=2&rft.issue=6&rft.spage=569&rft.isbn=&rft.btitle=&rft.title=Wiley+Interdisciplinary+Reviews%3A+Nanomedicine+and+Nanobiotechnology&rft.issn=19390041&rft_id=info:doi/10.1002%2Fwnan.108 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-05-01 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Risk assessment; Data processing; Physicochemical properties; Nutrients; nanoparticles; Media (culture); nanotechnology DO - http://dx.doi.org/10.1002/wnan.108 ER - TY - JOUR T1 - Antioxidants and Pulmonary Function Among Police Officers AN - 839706499; 14029607 AB - Objective: To examine associations of dietary antioxidant intake and pulmonary function. Methods: Antioxidant data (vitamins A, C, D, E, magnesium, and omega-3 fatty acids) were abstracted from food frequency questionnaires. Pulmonary function was measured using American Thoracic Society criteria. We used analysis of variance to investigate associations. Results: Among 79 police officers (57% male), forced vital capacity was positively and significantly associated with vitamin A after adjustment for age, gender, height, race, smoking status, and pack-years of smoking, and with magnesium after adjustment for those risk factors plus total calories, all supplement use, and abdominal height. Among current/former smokers only, mean levels of all pulmonary function measures were significantly associated with vitamin E; smoking status significantly modified these relationships. Conclusions: Increased intake of vitamin A, vitamin E (among current/former smokers only), and magnesium was associated with better pulmonary function. JF - Journal of Occupational and Environmental Medicine AU - Charles, LE AU - Burchfiel, C M AU - Mnatsakanova, A AU - Fekedulegn, D AU - Tinney-Zara, C AU - Joseph, P N AU - Schunemann, HJ AU - Violanti, J M AU - Andrew, ME AU - Ochs-Balcom, H M AD - National Institute for Occupational Safety and Health, HELD/BEB, MailStop L-4050, 1095 Willowdale Rd., Morgantown, WV 26505-2888, USA, lcharles@cdc.gov Y1 - 2010/11// PY - 2010 DA - Nov 2010 SP - 1124 EP - 1131 VL - 52 IS - 11 SN - 1076-2752, 1076-2752 KW - Risk Abstracts KW - Diets KW - Antioxidants KW - Smoking KW - vitamins KW - police KW - Gender KW - Fatty acids KW - Respiratory function KW - Magnesium KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839706499?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Antioxidants+and+Pulmonary+Function+Among+Police+Officers&rft.au=Charles%2C+LE%3BBurchfiel%2C+C+M%3BMnatsakanova%2C+A%3BFekedulegn%2C+D%3BTinney-Zara%2C+C%3BJoseph%2C+P+N%3BSchunemann%2C+HJ%3BViolanti%2C+J+M%3BAndrew%2C+ME%3BOchs-Balcom%2C+H+M&rft.aulast=Charles&rft.aufirst=LE&rft.date=2010-11-01&rft.volume=52&rft.issue=11&rft.spage=1124&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e3181f7cb4c LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Diets; Smoking; Antioxidants; vitamins; police; Gender; Fatty acids; Respiratory function; Magnesium DO - http://dx.doi.org/10.1097/JOM.0b013e3181f7cb4c ER - TY - JOUR T1 - Urine concentrations of a tobacco-specific nitrosamine carcinogen in the U.S. population from secondhand smoke exposure. AN - 763254831; 20833972 AB - The tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and its reduction product in the body, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), are potent pulmonary carcinogens. We have measured total NNAL in the U.S. population of tobacco users and nonsmokers exposed to secondhand smoke. We measured total urinary NNAL (free NNAL plus its glucuronides following hydrolysis) by using a sensitive and specific high-performance liquid chromatography/tandem mass spectrometry method. We calculated the percentage above the limit of detection, the 50th through 95th percentiles, and in some cases, geometric means for groups classified by age, gender, and race/ethnicity. Total urinary NNAL was measureable at or above its limit of detection (0.6 pg/mL) in 55% of the study participants, including 41% of nonsmokers. The population distribution of urinary NNAL included smoker and nonsmoker regions similar to the bimodal distribution of serum cotinine, and serum cotinine and total urinary NNAL were strongly correlated (r = 0.92; P < 0.001). Among nonsmokers, children had significantly higher concentrations of NNAL than did adults with the age of ≥20 years (P < 0.001). Among National Health and Nutrition Examination Survey participants, total NNAL was found at measurable levels in the urine of 41% of nonsmokers and in 87.5% of those with substantial secondhand-smoke exposure (with serum cotinine concentrations of 0.1-10 ng/mL). Children with the age of 6 to 11 years had the highest NNAL concentrations among all nonsmokers. We describe for the first time the distribution of total urinary NNAL in the entire U.S. population, including smokers and nonsmokers. NNAL was detected in 41% of all nonsmokers. ©2010 AACR. JF - Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology AU - Bernert, John T AU - Pirkle, James L AU - Xia, Yang AU - Jain, Ram B AU - Ashley, David L AU - Sampson, Eric J AD - Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA. jtb2@cdc.gov Y1 - 2010/11// PY - 2010 DA - November 2010 SP - 2969 EP - 2977 VL - 19 IS - 11 KW - 4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol KW - 0 KW - Biomarkers KW - Carcinogens KW - Nitrosamines KW - Pyridines KW - Tobacco Smoke Pollution KW - Index Medicus KW - United States KW - Young Adult KW - Mass Spectrometry KW - Smoking -- urine KW - Humans KW - Child KW - Nutrition Surveys KW - Chromatography, High Pressure Liquid KW - Age Distribution KW - Adult KW - Adolescent KW - Female KW - Male KW - Pyridines -- urine KW - Nitrosamines -- urine KW - Tobacco Smoke Pollution -- adverse effects KW - Biomarkers -- urine KW - Carcinogens -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/763254831?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cancer+epidemiology%2C+biomarkers+%26+prevention+%3A+a+publication+of+the+American+Association+for+Cancer+Research%2C+cosponsored+by+the+American+Society+of+Preventive+Oncology&rft.atitle=Urine+concentrations+of+a+tobacco-specific+nitrosamine+carcinogen+in+the+U.S.+population+from+secondhand+smoke+exposure.&rft.au=Bernert%2C+John+T%3BPirkle%2C+James+L%3BXia%2C+Yang%3BJain%2C+Ram+B%3BAshley%2C+David+L%3BSampson%2C+Eric+J&rft.aulast=Bernert&rft.aufirst=John&rft.date=2010-11-01&rft.volume=19&rft.issue=11&rft.spage=2969&rft.isbn=&rft.btitle=&rft.title=Cancer+epidemiology%2C+biomarkers+%26+prevention+%3A+a+publication+of+the+American+Association+for+Cancer+Research%2C+cosponsored+by+the+American+Society+of+Preventive+Oncology&rft.issn=1538-7755&rft_id=info:doi/10.1158%2F1055-9965.EPI-10-0711 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-02-22 N1 - Date created - 2010-11-09 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1158/1055-9965.EPI-10-0711 ER - TY - JOUR T1 - Treating malaria in pregnant women: a pressing problem AN - 1496889172; 13994260 JF - Lancet Infectious Diseases AU - Gutman, Julie AU - Kachur, S Patrick AD - Malaria Branch, US Centers for Disease Control and Prevention, Atlanta, GA, USA, spk0@cdc.gov Y1 - 2010/11// PY - 2010 DA - Nov 2010 SP - 739 EP - 740 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 10 IS - 11 SN - 1473-3099, 1473-3099 KW - ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Human diseases KW - Infectious diseases KW - Women KW - Malaria KW - Pregnancy KW - Public health KW - K 03400:Human Diseases KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1496889172?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Lancet+Infectious+Diseases&rft.atitle=Treating+malaria+in+pregnant+women%3A+a+pressing+problem&rft.au=Gutman%2C+Julie%3BKachur%2C+S+Patrick&rft.aulast=Gutman&rft.aufirst=Julie&rft.date=2010-11-01&rft.volume=10&rft.issue=11&rft.spage=739&rft.isbn=&rft.btitle=&rft.title=Lancet+Infectious+Diseases&rft.issn=14733099&rft_id=info:doi/10.1016%2FS1473-3099%2810%2970216-4 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-02-01 N1 - Last updated - 2015-10-28 N1 - SubjectsTermNotLitGenreText - Human diseases; Infectious diseases; Women; Malaria; Public health; Pregnancy DO - http://dx.doi.org/10.1016/S1473-3099(10)70216-4 ER - TY - JOUR T1 - A method for rapid, non-targeted screening for environmental contaminants in household dust AN - 869593859; 13947060 AB - Household dust can be a major source of human exposure to environmental contaminants such as polybrominated diphenyl ethers, pesticides, and other compounds. This work shows a screening technique that may be used to identify components in an environmental sample as xenobiotics based on mass spectral characteristics of classes of compounds that may be expected to be present in the environment. Household dust (SRM-2585) from the National Institute of Standards and Technology (NIST) was extracted with hexane using accelerated solvent extraction. Large molecules, such as triglycerides and fatty acids were removed with gel permeation chromatography. The extract was then concentrated and analyzed by comprehensive two dimensional gas chromatography coupled to a time of flight mass spectrometer. The resulting peak table was automatically filtered to identify compound classes such as phthalates, polycyclic aromatic hydrocarbons and their heterocyclic analogs, chlorinated compounds, brominated compounds, and nitro compounds. While phthalates can be identified by abundances at specific masses, the identification of the remaining classes is based on the identification of the molecular ion and identification of isotope clusters or other spectral characteristics. The technique detected compounds identified and quantified by NIST as well as compounds not identified by NIST in the sample. By comparison with concentrations determined by NIST for the analytes found, the technique is able to identify analytes in these compound classes at concentrations as low as 10-20 ng/g dust. JF - Journal of Chromatography A AU - Hilton, Donald C AU - Jones, Richard S AU - Sjoedin, Andreas AD - Centers for Disease Control and Prevention, 4770 Buford Highway, MS F-17, Atlanta, GA 30341, USA, dhilton@cdc.gov Y1 - 2010/10/29/ PY - 2010 DA - 2010 Oct 29 SP - 6851 EP - 6856 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 1217 IS - 44 SN - 0021-9673, 0021-9673 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Water Resources Abstracts; Aqualine Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources KW - Non-target KW - GCxGC-TOFMS KW - House dust KW - environmental contaminants KW - classification KW - pattern recognition KW - Molecular structure KW - Solvent extraction KW - Chromatographic techniques KW - Analogs KW - Dust KW - Agricultural Chemicals KW - Public Health KW - Pollutants KW - Aromatic hydrocarbons KW - Ethers KW - Screening KW - Solvents KW - Dusts KW - Analytical Methods KW - Pesticides KW - Fatty acids KW - Standards KW - SW 5040:Data acquisition KW - Q2 09405:Oil and gas KW - Q5 08502:Methods and instruments KW - AQ 00003:Monitoring and Analysis of Water and Wastes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/869593859?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Chromatography+A&rft.atitle=A+method+for+rapid%2C+non-targeted+screening+for+environmental+contaminants+in+household+dust&rft.au=Hilton%2C+Donald+C%3BJones%2C+Richard+S%3BSjoedin%2C+Andreas&rft.aulast=Hilton&rft.aufirst=Donald&rft.date=2010-10-29&rft.volume=1217&rft.issue=44&rft.spage=6851&rft.isbn=&rft.btitle=&rft.title=Journal+of+Chromatography+A&rft.issn=00219673&rft_id=info:doi/10.1016%2Fj.chroma.2010.08.039 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-05-01 N1 - Last updated - 2015-04-16 N1 - SubjectsTermNotLitGenreText - Molecular structure; Screening; Solvent extraction; Chromatographic techniques; Analogs; Pesticides; Fatty acids; Aromatic hydrocarbons; Dust; Public Health; Agricultural Chemicals; Pollutants; Analytical Methods; Solvents; Standards; Ethers; Dusts DO - http://dx.doi.org/10.1016/j.chroma.2010.08.039 ER - TY - JOUR T1 - Quantification of cyanuric acid residue in human urine using high performance liquid chromatography-tandem mass spectrometry. AN - 756668781; 20843749 AB - Concern has increased about the resulting health effects of exposure to melamine and its metabolic contaminant, cyanuric acid, after infants in China were fed baby formula milk products contaminated with these compounds. We have developed a selective and sensitive analytical method to quantify the amount of cyanuric acid in human urine. The sample preparation involved extracting free-form cyanuric acid in human urine using anion exchange solid phase extraction. Cyanuric acid was separated from its urinary matrix components on the polymeric strong anion exchange analytical column; the analysis was performed by high performance liquid chromatography-tandem mass spectrometry using negative mode electrospray ionization interface. Quantification was performed using isotope dilution calibration covering the concentration range of 1.00-200ng/mL. The limit of detection was 0.60ng/mL and the relative standard deviations were 2.8-10.5% across the calibration range. The relative recovery of cyanuric acid was 100-104%. Our method is suitable to detect urinary concentrations of cyanuric acid caused by either environmental exposures or emerging poisoning events. Published by Elsevier B.V. JF - Journal of chromatography. B, Analytical technologies in the biomedical and life sciences AU - Panuwet, Parinya AU - Wade, Erin L AU - Nguyen, Johnny V AU - Montesano, M Angela AU - Needham, Larry L AU - Barr, Dana Boyd AD - Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA. dzn6@cdc.gov Y1 - 2010/10/15/ PY - 2010 DA - 2010 Oct 15 SP - 2916 EP - 2922 VL - 878 IS - 28 KW - Triazines KW - 0 KW - cyanuric acid KW - H497R4QKTZ KW - Index Medicus KW - Sensitivity and Specificity KW - Drug Stability KW - Reproducibility of Results KW - Humans KW - Solid Phase Extraction KW - Tandem Mass Spectrometry -- methods KW - Chromatography, High Pressure Liquid -- methods KW - Triazines -- urine KW - Triazines -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/756668781?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+chromatography.+B%2C+Analytical+technologies+in+the+biomedical+and+life+sciences&rft.atitle=Quantification+of+cyanuric+acid+residue+in+human+urine+using+high+performance+liquid+chromatography-tandem+mass+spectrometry.&rft.au=Panuwet%2C+Parinya%3BWade%2C+Erin+L%3BNguyen%2C+Johnny+V%3BMontesano%2C+M+Angela%3BNeedham%2C+Larry+L%3BBarr%2C+Dana+Boyd&rft.aulast=Panuwet&rft.aufirst=Parinya&rft.date=2010-10-15&rft.volume=878&rft.issue=28&rft.spage=2916&rft.isbn=&rft.btitle=&rft.title=Journal+of+chromatography.+B%2C+Analytical+technologies+in+the+biomedical+and+life+sciences&rft.issn=1873-376X&rft_id=info:doi/10.1016%2Fj.jchromb.2010.08.019 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-01-24 N1 - Date created - 2010-10-05 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.jchromb.2010.08.019 ER - TY - JOUR T1 - Global use of Haemophilus influenzae type b conjugate vaccine AN - 867749921; 14780061 AB - Haemophilus influenzae type b (Hib) conjugate vaccines have been underutilized globally. We report progress in global use of Hib vaccines included in national immunization schedules. The number of countries using Hib vaccine increased from 89/193 (46%) in 2004 to 158/193 (82%) by the end of 2009. The increase was greatest among low-income countries eligible for financial support from the GAVI Alliance [13/75 (17%) in 2004, 60/72 (83%) by the end of 2009], and can be attributed to various factors. Additional efforts are still needed to increase vaccine adoption in lower middle income countries [20/31 (65%) by the end of 2009]. JF - Vaccine AU - Ojo, Linda R AU - O'Loughlin, Rosalyn E AU - Cohen, Adam L AU - Loo, Jennifer D AU - Edmond, Karen M AU - Shetty, Sharmila S AU - Bear, Allyson P AU - Privor-Dumm, Lois AU - Griffiths, Ulla K AU - Hajjeh, Rana AD - Respiratory Diseases Branch, Division of Bacterial Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road NE, MS C-23, Atlanta, GA 30333, USA, ALCohen1@cdc.gov Y1 - 2010/10/08/ PY - 2010 DA - 2010 Oct 08 SP - 7117 EP - 7122 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 28 IS - 43 SN - 0264-410X, 0264-410X KW - Virology & AIDS Abstracts; Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Haemophilus influenzae KW - Adoption KW - Vaccines KW - Immunization KW - V 22490:Miscellaneous KW - F 06905:Vaccines KW - J 02350:Immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/867749921?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Global+use+of+Haemophilus+influenzae+type+b+conjugate+vaccine&rft.au=Ojo%2C+Linda+R%3BO%27Loughlin%2C+Rosalyn+E%3BCohen%2C+Adam+L%3BLoo%2C+Jennifer+D%3BEdmond%2C+Karen+M%3BShetty%2C+Sharmila+S%3BBear%2C+Allyson+P%3BPrivor-Dumm%2C+Lois%3BGriffiths%2C+Ulla+K%3BHajjeh%2C+Rana&rft.aulast=Ojo&rft.aufirst=Linda&rft.date=2010-10-08&rft.volume=28&rft.issue=43&rft.spage=7117&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/10.1016%2Fj.vaccine.2010.07.074 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-05-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Adoption; Vaccines; Immunization; Haemophilus influenzae DO - http://dx.doi.org/10.1016/j.vaccine.2010.07.074 ER - TY - JOUR T1 - Factors Associated with Parent-Child Communication About HIV/AIDS in the United States and Kenya: A Cross-Cultural Comparison AN - 860385271; 13838400 AB - This study explored parent-child communication about HIV/AIDS among two populations disproportionately affected by HIV. Similar computer-assisted surveys were completed by parents of pre-teens, including 1,115 African American parents of 9-12-year-old children in southeastern US and 403 parents of 10-12-year-old children in Nyanza Province, Kenya. Multivariate analyses identified factors associated with parental report of ever talking to their child about HIV/AIDS. Twenty-nine percent of US parents and 40% in Kenya had never talked to their pre-teen about HIV/AIDS. In both countries, communication was more likely if parents perceived their child to be ready to learn about sex topics, had gotten information to educate their child about sex, and had greater sexual communication responsiveness (skill, comfort, and confidence communicating about sexuality). Programs are needed that help parents assess children's readiness to learn about sexual issues; access accurate information about adolescent sexual risks; and acquire the responsiveness needed to discuss sexual issues, including HIV/AIDS. JF - AIDS and Behavior AU - Poulsen, Melissa N AU - Miller, Kim S AU - Lin, Carol AU - Fasula, Amy AU - Vandenhoudt, Hilde AU - Wyckoff, Sarah C AU - Ochura, Juliet AU - Obong'o, Christopher O AU - Forehand, Rex AD - Global AIDS Program, NCHHSTP, Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Mailstop E-45, Atlanta, GA, 30333, USA, mpoulsen@cdc.gov Y1 - 2010/10// PY - 2010 DA - Oct 2010 SP - 1083 EP - 1094 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 14 IS - 5 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Risk Abstracts KW - Acquired immune deficiency syndrome KW - Adolescence KW - Children KW - Sexuality KW - Kenya KW - Communications KW - Human immunodeficiency virus KW - Perception KW - Multivariate analysis KW - Kenya, Nyanza KW - Adolescents KW - Ethnic groups KW - Sex KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/860385271?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Factors+Associated+with+Parent-Child+Communication+About+HIV%2FAIDS+in+the+United+States+and+Kenya%3A+A+Cross-Cultural+Comparison&rft.au=Poulsen%2C+Melissa+N%3BMiller%2C+Kim+S%3BLin%2C+Carol%3BFasula%2C+Amy%3BVandenhoudt%2C+Hilde%3BWyckoff%2C+Sarah+C%3BOchura%2C+Juliet%3BObong%27o%2C+Christopher+O%3BForehand%2C+Rex&rft.aulast=Poulsen&rft.aufirst=Melissa&rft.date=2010-10-01&rft.volume=14&rft.issue=5&rft.spage=1083&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-009-9612-4 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-04-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Sexuality; Acquired immune deficiency syndrome; Multivariate analysis; Adolescence; Children; Sex; Communications; Perception; Human immunodeficiency virus; Ethnic groups; Adolescents; Kenya; Kenya, Nyanza DO - http://dx.doi.org/10.1007/s10461-009-9612-4 ER - TY - JOUR T1 - Protecting the planet and its people: How do interventions to promote environmental sustainability and occupational safety and health overlap? AN - 856762591; 13998130 AB - Problem: The challenges of both occupational safety and health and environmental sustainability require large-scale behavior change for meaningful improvements to occur. Environmental sustainability, or the 'green movement' has received far more attention recently, and certain strategies and recommendations from interventions designed for promoting pro-environmental behaviors may inform efforts to intervene on critical behaviors for improving occupational safety and health. Method: A survey of the literature regarding behavioral interventions for both environmental sustainability and occupational safety and health was conducted. Several theoretical approaches are reviewed, and successful approaches from each domain are identified, as well as parallel challenges and points for crossover. Recommendations are provided for adapting environmental sustainability intervention approaches for occupational safety and health applications. Impact on Industry: Safety and health leaders may achieve sustainable improvements in worker safety and health by harnessing the momentum of the green movement and adapting successful intervention approaches from the environmental sustainability domain. JF - Journal of Safety Research AU - Cunningham, Thomas R AU - Galloway-Williams, Neville AU - Geller, EScott AD - National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, 4676 Columbia Parkway, MS C-10, Cincinnati, OH 45226, tcunningham@cdc.gov Y1 - 2010/10// PY - 2010 DA - Oct 2010 SP - 407 EP - 416 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK VL - 41 IS - 5 SN - 0022-4375, 0022-4375 KW - Health & Safety Science Abstracts KW - Occupational safety KW - Sustainable development KW - green revolution KW - adaptability KW - intervention KW - Reviews KW - sustainability KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/856762591?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Safety+Research&rft.atitle=Protecting+the+planet+and+its+people%3A+How+do+interventions+to+promote+environmental+sustainability+and+occupational+safety+and+health+overlap%3F&rft.au=Cunningham%2C+Thomas+R%3BGalloway-Williams%2C+Neville%3BGeller%2C+EScott&rft.aulast=Cunningham&rft.aufirst=Thomas&rft.date=2010-10-01&rft.volume=41&rft.issue=5&rft.spage=407&rft.isbn=&rft.btitle=&rft.title=Journal+of+Safety+Research&rft.issn=00224375&rft_id=info:doi/10.1016%2Fj.jsr.2010.08.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-03-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Reviews; intervention; Occupational safety; Sustainable development; green revolution; sustainability; adaptability DO - http://dx.doi.org/10.1016/j.jsr.2010.08.002 ER - TY - JOUR T1 - Genetic Factors Associated with Elevated Carbapenem Resistance in KPC-Producing Klebsiella pneumoniae AN - 839693886; 13971163 AB - In the United States, the most prevalent mechanism of carbapenem resistance among Enterobacteriaceae is the production of a Klebsiella pneumoniae carbapenemase (KPC). KPC-producing isolates often exhibit a range of carbapenem MICs. To better understand the factors that contribute to overall carbapenem resistance, we analyzed 27 KPC-producing K. pneumoniae isolates with different levels of carbapenem resistance, 11 with low-level (i.e., meropenem or imipenem MIC 4 kg/ml), 2 with intermediate-level (i.e., meropenem and imipenem MIC = 8 kg/ml), and 14 with high-level (i.e., imipenem or meropenem MIC 16 kg/ml) carbapenem resistance, that were received from throughout the United States. Among 14 isolates that exhibited high-level carbapenem resistance, Western blot analysis indicated that 10 produced an elevated amount of KPC. These isolates either contained an increased blaKPC gene copy number (n = 3) or had deletions directly upstream of the blaKPC gene (n = 7). Four additional isolates lacked elevated KPC production but had high-level carbapenem resistance. Porin sequencing analysis identified 22 isolates potentially lacking a functional OmpK35 and three isolates potentially lacking a functional OmpK36. The highest carbapenem MICs were found in two isolates that lacked both functioning porins and produced elevated amounts of KPC. The 11 isolates with low-level carbapenem resistance contained neither an upstream deletion nor increased blaKPC copy number. These results suggest that both blaKPC copy number and deletions in the upstream genetic environment affect the level of KPC production and may contribute to high-level carbapenem resistance in KPC-producing K. pneumoniae, particularly when coupled with OmpK36 porin loss. JF - Antimicrobial Agents & Chemotherapy AU - Kitchel, Brandon AU - Rasheed, JKamile AU - Endimiani, Andrea AU - Hujer, Andrea M AU - Anderson, Karen F AU - Bonomo, Robert A AU - Patel, Jean B AD - Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, bkitchel@cdc.gov Y1 - 2010/10// PY - 2010 DA - Oct 2010 SP - 4201 EP - 4207 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 54 IS - 10 SN - 0066-4804, 0066-4804 KW - Genetics Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology KW - Western blotting KW - Genetic factors KW - Porins KW - Carbapenems KW - carbapenemase KW - Minimum inhibitory concentration KW - copy number KW - Imipenem KW - Gene deletion KW - Meropenem KW - Enterobacteriaceae KW - Klebsiella pneumoniae KW - J 02310:Genetics & Taxonomy KW - A 01350:Microbial Resistance KW - G 07770:Bacteria UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839693886?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Genetic+Factors+Associated+with+Elevated+Carbapenem+Resistance+in+KPC-Producing+Klebsiella+pneumoniae&rft.au=Kitchel%2C+Brandon%3BRasheed%2C+JKamile%3BEndimiani%2C+Andrea%3BHujer%2C+Andrea+M%3BAnderson%2C+Karen+F%3BBonomo%2C+Robert+A%3BPatel%2C+Jean+B&rft.aulast=Kitchel&rft.aufirst=Brandon&rft.date=2010-10-01&rft.volume=54&rft.issue=10&rft.spage=4201&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.00008-10 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Western blotting; Genetic factors; Gene deletion; Meropenem; Porins; Carbapenems; carbapenemase; Minimum inhibitory concentration; Imipenem; copy number; Enterobacteriaceae; Klebsiella pneumoniae DO - http://dx.doi.org/10.1128/AAC.00008-10 ER - TY - JOUR T1 - Evaluation of Antineoplastic Drug Exposure of Health Care Workers at Three University-Based US Cancer Centers AN - 839687391; 13984200 AB - Objective: This study evaluated health care worker exposure to antineoplastic drugs. Methods: A cross-sectional study examined environmental samples from pharmacy and nursing areas. A 6-week diary documented tasks involving those drags. Urine was analyzed for two specific drugs, and blood samples were analyzed by the comet assay. Results: Sixty-eight exposed and 53 nonexposed workers were studied. Exposed workers recorded 10,000 drug-handling events during the 6-week period. Sixty percent of wipe samples were positive for at least one of the five drags measured. Cyclophosphamide was most commonly detected, followed by 5-fluorouracil. Three of the 68 urine samples were positive for one drug. No genetic damage was detected in exposed workers using the comet assay. Conclusions: Despite following recommended safe-handling practices, workplace contamination with antineoplastic drugs in pharmacy and nursing areas continues at these locations. JF - Journal of Occupational and Environmental Medicine AU - Connor, TH AU - DeBord, D G AU - Pretty, J R AU - Oliver AU - Roth, T S AU - Lees, PSJ AU - Krieg, EF Jr AU - Rogers, B AU - Escalante, C P AU - Toennis, CA AU - Clark, J C AU - Johnson, B C AU - McDiarmid, MA AD - Division of Applied Research and Technology, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, MS C-23, 4676 Columbia Parkway, Cincinnati, OH 45226, USA, tmc6@cdc.gov Y1 - 2010/10// PY - 2010 DA - Oct 2010 SP - 1019 EP - 1027 VL - 52 IS - 10 SN - 1076-2752, 1076-2752 KW - Toxicology Abstracts KW - 5-Fluorouracil KW - Contamination KW - Urine KW - Nursing KW - Antineoplastic drugs KW - Comet assay KW - Cyclophosphamide KW - Drugs KW - Occupational exposure KW - Medical personnel KW - Cancer KW - X 24310:Pharmaceuticals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839687391?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Evaluation+of+Antineoplastic+Drug+Exposure+of+Health+Care+Workers+at+Three+University-Based+US+Cancer+Centers&rft.au=Connor%2C+TH%3BDeBord%2C+D+G%3BPretty%2C+J+R%3BOliver%3BRoth%2C+T+S%3BLees%2C+PSJ%3BKrieg%2C+EF+Jr%3BRogers%2C+B%3BEscalante%2C+C+P%3BToennis%2C+CA%3BClark%2C+J+C%3BJohnson%2C+B+C%3BMcDiarmid%2C+MA&rft.aulast=Connor&rft.aufirst=TH&rft.date=2010-10-01&rft.volume=52&rft.issue=10&rft.spage=1019&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e3181f72b63 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - 5-Fluorouracil; Contamination; Urine; Nursing; Antineoplastic drugs; Cyclophosphamide; Comet assay; Drugs; Cancer; Medical personnel; Occupational exposure DO - http://dx.doi.org/10.1097/JOM.0b013e3181f72b63 ER - TY - JOUR T1 - Dissemination of an Enterococcus Inc18-Like vanA Plasmid Associated with Vancomycin-Resistant Staphylococcus aureus AN - 839685297; 13971169 AB - Of the 9 vancomycin-resistant Staphylococcus aureus (VRSA) cases reported to date in the literature, 7 occurred in Michigan. In 5 of the 7 Michigan VRSA cases, an Inc18-like vanA plasmid was identified in the VRSA isolate and/or an associated vancomycin-resistant Enterococcus (VRE) isolate from the same patient. This plasmid may play a critical role in the emergence of VRSA. We studied the geographical distribution of the plasmid by testing 1,641 VRE isolates from three separate collections by PCR for plasmid-specific genes traA, repR, and vanA. Isolates from one collection (phase 2) were recovered from surveillance cultures collected in 17 hospitals in 13 states. All VRE isolates from 2 Michigan institutions (n = 386) and between 60 and 70 VRE isolates (n = 883) from the other hospitals were tested. Fifteen VRE isolates (3.9%) from Michigan were positive for an Inc18-like vanA plasmid (9 E. faecalis [12.5%], 3 E. faecium [1.0%], 2 E. avium, and 1 E. raffinosus). Six VRE isolates (0.6%) from outside Michigan were positive (3 E. faecalis [2.7%] and 3 E. faecium [0.4%]). Of all E. faecalis isolates tested, 6.0% were positive for the plasmid, compared to 0.6% for E. faecium and 3.0% for other spp. Fourteen of the 15 plasmid-positive isolates from Michigan had the same Tn1546 insertion site location as the VRSA-associated Inc18-like plasmid, whereas 5 of 6 plasmid-positive isolates from outside Michigan differed in this characteristic. Most plasmid-positive E. faecalis isolates demonstrated diverse patterns by PFGE, with the exception of three pairs with indistinguishable patterns, suggesting that the plasmid is mobile in nature. Although VRE isolates with the VRSA-associated Inc18-like vanA plasmid were more common in Michigan, they remain rare. Periodic surveillance of VRE isolates for the plasmid may be useful in predicting the occurrence of VRSA. JF - Antimicrobial Agents & Chemotherapy AU - Zhu, Wenming AU - Murray, Patrick R AU - Huskins, WCharles AU - Jernigan, John A AU - McDonald, Lawrence C AU - Clark, Nancye C AU - Anderson, Karen F AU - McDougal, Linda K AU - Hageman, Jeff C AU - Olsen-Rasmussen, Melissa AD - Division of Scientific Resources, Centers for Disease Control and Prevention, MS-G08, 1600 Clifton Road, Atlanta, Georgia, vzp4@cdc.gov Y1 - 2010/10// PY - 2010 DA - Oct 2010 SP - 4314 EP - 4320 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 54 IS - 10 SN - 0066-4804, 0066-4804 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology KW - Geographical distribution KW - Enterococcus KW - Polymerase chain reaction KW - Site location KW - Staphylococcus aureus KW - Plasmids KW - Hospitals KW - A 01340:Antibiotics & Antimicrobials KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839685297?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Dissemination+of+an+Enterococcus+Inc18-Like+vanA+Plasmid+Associated+with+Vancomycin-Resistant+Staphylococcus+aureus&rft.au=Zhu%2C+Wenming%3BMurray%2C+Patrick+R%3BHuskins%2C+WCharles%3BJernigan%2C+John+A%3BMcDonald%2C+Lawrence+C%3BClark%2C+Nancye+C%3BAnderson%2C+Karen+F%3BMcDougal%2C+Linda+K%3BHageman%2C+Jeff+C%3BOlsen-Rasmussen%2C+Melissa&rft.aulast=Zhu&rft.aufirst=Wenming&rft.date=2010-10-01&rft.volume=54&rft.issue=10&rft.spage=4314&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.00185-10 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Geographical distribution; Polymerase chain reaction; Site location; Plasmids; Hospitals; Enterococcus; Staphylococcus aureus DO - http://dx.doi.org/10.1128/AAC.00185-10 ER - TY - JOUR T1 - Factors Associated with the Prevalence of Non-ROPS Tractors on Farms in the U.S. AN - 821736678; 14029798 AB - Rollover protective structures (ROPS) are an effective engineering control known to prevent tractor overturn deaths, the leading cause of occupational fatalities for farmers and farm workers in the U.S. However, the use of ROPS is known to vary greatly from farm to farm. A national sample of 11,458 farm operators from the 2004 Occupational Injury Surveillance of Production Agriculture (OISPA) survey was used to assess the association between the prevalence of ROPS and ten farm operator and farm demographic variables using logistic regression. The variable were: operator's age, operator's sex, operator's education, farm sales, full- or part-time farming, acreage, type of operation, number of hired workers, number of injuries, and region. All ten variables were found to have significant associations with the prevalence of non-ROPS tractors on farms in the univariate logistic regressions. For the multivariate model, all variables except for the sex of the farm operator remained significant. Farms with less than three adult injuries, no hired workers, less than 300 acres in size, a Midwest location, and a primary farm type of tobacco, fruit and nuts, dairy, or poultry and eggs all had adjusted odds ratios of 2 or greater. Increasing the prevalence of ROPS-equipped tractors is essential for reducing the leading cause of death on farms, tractor overturns. Economic factors play a major role in the prevalence and distribution of non-ROPS tractors on farms. The identified associations can be used to effectively target areas of the U.S. for ROPS promotion activities. JF - Journal of Agricultural Safety and Health AU - Myers, J R AD - Division of Safety Research, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, West Virginia 26505, USA, jrmyers@cdc.gov Y1 - 2010/10// PY - 2010 DA - October 2010 SP - 265 EP - 278 VL - 16 IS - 4 SN - 1074-7583, 1074-7583 KW - Health & Safety Science Abstracts KW - Mortality KW - USA KW - Education KW - Dairies KW - safety engineering KW - Injuries KW - farms KW - fruits KW - Tobacco KW - Agricultural equipment KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/821736678?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Agricultural+Safety+and+Health&rft.atitle=Factors+Associated+with+the+Prevalence+of+Non-ROPS+Tractors+on+Farms+in+the+U.S.&rft.au=Myers%2C+J+R&rft.aulast=Myers&rft.aufirst=J&rft.date=2010-10-01&rft.volume=16&rft.issue=4&rft.spage=265&rft.isbn=&rft.btitle=&rft.title=Journal+of+Agricultural+Safety+and+Health&rft.issn=10747583&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-12-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Mortality; Dairies; Education; safety engineering; Injuries; farms; fruits; Tobacco; Agricultural equipment; USA ER - TY - JOUR T1 - Injury Surveillance for Youth on Farms in the U.S., 2006 AN - 821736131; 14029799 AB - In order to provide injury surveillance for youth on farms in the U.S., the National Institute for Occupational Safety and Health (NIOSH), in partnership with the USDA, developed the Childhood Agricultural Injury Survey (CAIS). CAIS data for all youth less than 20 years of age on farms have been collected for the calendar years of 1998, 2001, 2004, and 2006. CAIS data from 2006 indicated that an estimated 30.7 million youth lived on, worked on, or visited U.S. farms. These youth experienced almost 23,000 injuries while on the farm. The majority of these injuries occurred to males (15,223) and youth between the ages of 10 and 15 years (10,158). Approximately 25% (5,773) of the injuries were related to work being done on the farm. Youth living on the farm incurred 51% (11,654) of the injuries, hired youth sustained 6% (1,363), and 40% were to visiting youth (9,729). Although youth injuries on farms have declined by 30% since 1998, the numbers are still unacceptably high. Further indepth evaluation of subsets of the youth population may serve to better direct safety intervention programs and research. JF - Journal of Agricultural Safety and Health AU - Hendricks, K J AU - Goldcamp, E M AD - Division of Safety Research, National Institute for Occupational Safety and Health, M/S 1808, 1095 Willowdale Rd., Morgantown, WV 26505, USA, Khendricks@cdc.gov Y1 - 2010/10// PY - 2010 DA - October 2010 SP - 279 EP - 291 VL - 16 IS - 4 SN - 1074-7583, 1074-7583 KW - Health & Safety Science Abstracts KW - USA KW - Age KW - Injuries KW - farms KW - intervention KW - Occupational safety KW - Children KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/821736131?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Agricultural+Safety+and+Health&rft.atitle=Injury+Surveillance+for+Youth+on+Farms+in+the+U.S.%2C+2006&rft.au=Hendricks%2C+K+J%3BGoldcamp%2C+E+M&rft.aulast=Hendricks&rft.aufirst=K&rft.date=2010-10-01&rft.volume=16&rft.issue=4&rft.spage=279&rft.isbn=&rft.btitle=&rft.title=Journal+of+Agricultural+Safety+and+Health&rft.issn=10747583&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-12-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Age; Injuries; intervention; farms; Occupational safety; Children; USA ER - TY - JOUR T1 - Dissolution of cemented carbide powders in artificial sweat: implications for cobalt sensitization and contact dermatitis AN - 817610732; 13981733 AB - Skin exposure to cobalt-containing materials can cause systemic immune sensitization and upon repeat contact, elicitation of allergic contact dermatitis (ACD). Data on cobalt dissolution rates are needed to calculate uptake through skin and for development of models to understand risk of sensitization or dermatitis. The purpose of this research was to measure the dissolution kinetics of feedstock and process-sampled powders encountered in the production of hard metal alloys using artificial sweat. The physicochemical properties of each material were characterized prior to evaluation of dissolution behavior. Variations in artificial sweat solvent pH and chemistry were used to understand critical factors in dissolution. Dissolution of cobalt, tungsten, and tungsten carbide was often biphasic with the initial rapid phase being up to three orders of magnitude faster than the latter long-term phase. Artificial sweat pH did not influence dissolution of cobalt or tungsten carbide. Solvent composition had little influence on observed dissolution rates; however, vitamin E suppressed the dissolution of cobalt and tungsten carbide from sintered particles obtained from a chamfer grinder. There was no effect of particle size on dissolution of feedstock cobalt, tungsten, tungsten carbide, and admixture powders. Particle physicochemical properties influenced observed dissolution rates with more cobalt and tungsten carbide dissolving from chamfer grinder particles compared to the feedstock powders or admixture powder. Calculations using the observed dissolution rates revealed that skin exposure concentrations were similar to concentrations known to induce cobalt sensitization and elicit ACD. Observed dissolution rates for cobalt in artificial sweat indicate that dermal uptake may be sufficient to induce cobalt sensitization and allergic dermatitis. JF - Journal of Environmental Monitoring AU - Stefaniak, AB AU - Harvey, C J AU - Virji, MA AU - Day, G A AD - National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Mailstop H-2800, Morgantown, WV, 26505, USA, AStefaniak@cdc.gov Y1 - 2010/10// PY - 2010 DA - October 2010 SP - 1815 EP - 1822 VL - 12 IS - 10 SN - 1464-0325, 1464-0325 KW - Risk Abstracts; Environment Abstracts; Pollution Abstracts KW - Metals KW - Skin KW - Contact dermatitis KW - Cobalt KW - contact dermatitis KW - Physicochemical properties KW - Solvents KW - Particulates KW - pH KW - Tungsten KW - R2 23060:Medical and environmental health KW - P 6000:TOXICOLOGY AND HEALTH KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/817610732?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+Monitoring&rft.atitle=Dissolution+of+cemented+carbide+powders+in+artificial+sweat%3A+implications+for+cobalt+sensitization+and+contact+dermatitis&rft.au=Stefaniak%2C+AB%3BHarvey%2C+C+J%3BVirji%2C+MA%3BDay%2C+G+A&rft.aulast=Stefaniak&rft.aufirst=AB&rft.date=2010-10-01&rft.volume=12&rft.issue=10&rft.spage=1815&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+Monitoring&rft.issn=14640325&rft_id=info:doi/10.1039%2Fc0em00269k LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-12-01 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Metals; Contact dermatitis; Skin; contact dermatitis; Cobalt; Physicochemical properties; Solvents; Particulates; pH; Tungsten DO - http://dx.doi.org/10.1039/c0em00269k ER - TY - JOUR T1 - Optimal swab processing recovery method for detection of bioterrorism-related Francisella tularensis by real-time PCR AN - 762266848; 13680042 AB - Francisella tularensis, the etiological agent of tularemia, is regarded as a potential bioterrorism agent. The advent of bioterrorism has heightened awareness of the need for validated methods for processing environmental samples. In this study we determined the optimal method for processing environmental swabs for the recovery and subsequent detection of F. tularensis by the use of real-time PCR assays. Four swab processing recovery methods were compared: heat, sonication, vortexing, and the Swab Extraction Tube System (SETS). These methods were evaluated using cotton, foam, polyester and rayon swabs spiked with six pathogenic strains of F. tularensis. Real-time PCR analysis using a multi-target 5a super(2)nuclease assay for F. tularensis showed that the use of the SETS method resulted in the best limit of detection when evaluated using multiple strains of F. tularensis. We demonstrated also that the efficiency of F. tularensis recovery from swab specimens was not equivalent for all swab processing methodologies and, thus, that this variable can affect real-time PCR assay sensitivity. The effectiveness of the SETS method was independent of the automated DNA extraction method and real-time PCR platforms used. In conclusion, diagnostic laboratories can now potentially incorporate the SETS method into specimen processing protocols for the rapid and efficient detection of F. tularensis by real-time PCR during laboratory bioterrorism-related investigations. JF - Journal of Microbiological Methods AU - Walker, Roblena E AU - Petersen, Jeannine M AU - Stephens, Kenyatta W AU - Dauphin, Leslie A AD - Bioterrorism Rapid Response and Advanced Technology (BRRAT) Laboratory, Division of Bioterrorism Preparedness and Response (DBPR), Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA, LDauphin@CDC.GOV Y1 - 2010/10// PY - 2010 DA - Oct 2010 SP - 42 EP - 47 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 83 IS - 1 SN - 0167-7012, 0167-7012 KW - Microbiology Abstracts B: Bacteriology; Water Resources Abstracts; Biotechnology and Bioengineering Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Assay KW - Polymerase chain reaction KW - Francisella tularensis KW - W 30900:Methods KW - SW 7060:Research facilities KW - A 01300:Methods KW - J 02300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/762266848?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Microbiological+Methods&rft.atitle=Optimal+swab+processing+recovery+method+for+detection+of+bioterrorism-related+Francisella+tularensis+by+real-time+PCR&rft.au=Walker%2C+Roblena+E%3BPetersen%2C+Jeannine+M%3BStephens%2C+Kenyatta+W%3BDauphin%2C+Leslie+A&rft.aulast=Walker&rft.aufirst=Roblena&rft.date=2010-10-01&rft.volume=83&rft.issue=1&rft.spage=42&rft.isbn=&rft.btitle=&rft.title=Journal+of+Microbiological+Methods&rft.issn=01677012&rft_id=info:doi/10.1016%2Fj.mimet.2010.07.015 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-11-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Polymerase chain reaction; Assay; Francisella tularensis DO - http://dx.doi.org/10.1016/j.mimet.2010.07.015 ER - TY - JOUR T1 - Evaluating and regulating lead in synthetic turf. AN - 756659168; 20884393 AB - In 2007, a synthetic turf recreational field in Newark, New Jersey, was closed because lead was found in synthetic turf fibers and in surface dust at concentrations exceeding hazard criteria. Consequently, public health professionals across the country began testing synthetic turf to determine whether it represented a lead hazard. Currently, no standardized methods exist to test for lead in synthetic turf or to assess lead hazards. Our objectives were to increase awareness of potential lead exposure from synthetic turf by presenting data showing elevated lead in fibers and turf-derived dust; identify risk assessment uncertainties; recommend that federal and/or state agencies determine appropriate methodologies for assessing lead in synthetic turf; and recommend an interim standardized approach for sampling, interpreting results, and taking health-protective actions. Data collected from recreational fields and child care centers indicate lead in synthetic turf fibers and dust at concentrations exceeding the Consumer Product Safety Improvement Act of 2008 statutory lead limit of 300 mg/kg for consumer products intended for use by children, and the U.S. Environmental Protection Agency's lead-dust hazard standard of 40 µg/ft² for floors. Synthetic turf can deteriorate to form dust containing lead at levels that may pose a risk to children. Given elevated lead levels in turf and dust on recreational fields and in child care settings, it is imperative that a consistent, nationwide approach for sampling, assessment, and action be developed. In the absence of a standardized approach, we offer an interim approach to assess potential lead hazards when evaluating synthetic turf. JF - Environmental health perspectives AU - Van Ulirsch, Gregory AU - Gleason, Kevin AU - Gerstenberger, Shawn AU - Moffett, Daphne B AU - Pulliam, Glenn AU - Ahmed, Tariq AU - Fagliano, Jerald AD - Division of Health Assessment and Consultation, Agency for Toxic Substances and Disease Registry, Atlanta, Georgia 30341-3717 , USA. gulirsch@cdc.gov Y1 - 2010/10// PY - 2010 DA - October 2010 SP - 1345 EP - 1349 VL - 118 IS - 10 KW - Soil Pollutants KW - 0 KW - Lead KW - 2P299V784P KW - Index Medicus KW - Public Health Practice KW - Lead -- analysis KW - Soil Pollutants -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/756659168?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+health+perspectives&rft.atitle=Evaluating+and+regulating+lead+in+synthetic+turf.&rft.au=Van+Ulirsch%2C+Gregory%3BGleason%2C+Kevin%3BGerstenberger%2C+Shawn%3BMoffett%2C+Daphne+B%3BPulliam%2C+Glenn%3BAhmed%2C+Tariq%3BFagliano%2C+Jerald&rft.aulast=Van+Ulirsch&rft.aufirst=Gregory&rft.date=2010-10-01&rft.volume=118&rft.issue=10&rft.spage=1345&rft.isbn=&rft.btitle=&rft.title=Environmental+health+perspectives&rft.issn=1552-9924&rft_id=info:doi/10.1289%2Fehp.1002239 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-01-13 N1 - Date created - 2010-10-04 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Environ Sci Technol. 2001 May 15;35(10):2078-83 [11393990] Environ Health Perspect. 2002 Oct;110(10):969-83 [12361921] AIHA J (Fairfax, Va). 2003 Jul-Aug;64(4):528-32 [12908870] J Expo Sci Environ Epidemiol. 2008 Nov;18(6):533-4 [18936757] Environ Res. 1995 Feb;68(2):114-23 [7601072] Environ Res. 1999 Aug;81(2):130-41 [10433844] MMWR Recomm Rep. 2007 Nov 2;56(RR-8):1-16 [17975528] Environ Res. 1994 May;65(2):291-301 [8187743] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1289/ehp.1002239 ER - TY - JOUR T1 - Travel Characteristics and Risk-Taking Attitudes in Youths Traveling to Nonindustrialized Countries AN - 877591771; 13666582 AB - Background. International travel to developing countries is increasing with rising levels of disposable income; this trend is seen in both adults and children. Risk-taking attitude is fundamental to research on the prevention of risky health behaviors, which can be an indicator of the likelihood of experiencing illness or injury during travel. The aim of this study is to investigate whether risk-taking attitudes of youths are associated with travel characteristics and likelihood of experiencing illness or injury while traveling to nonindustrialized countries. JF - Journal of Travel Medicine AU - Han, Pauline AU - Balaban, Victor AU - Marano, Cinzia AD - 1Travelers' Health Branch, Division of Global Migration and Quarantine, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA, phan@cdc.gov Y1 - 2010/09// PY - 2010 DA - Sep 2010 SP - 316 EP - 321 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 USA VL - 17 IS - 5 SN - 1195-1982, 1195-1982 KW - Risk Abstracts KW - Children KW - Developing countries KW - Injuries KW - Travel KW - attitudes KW - income KW - prevention KW - risk taking KW - R2 23070:Economics, organization UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/877591771?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Travel+Medicine&rft.atitle=Travel+Characteristics+and+Risk-Taking+Attitudes+in+Youths+Traveling+to+Nonindustrialized+Countries&rft.au=Han%2C+Pauline%3BBalaban%2C+Victor%3BMarano%2C+Cinzia&rft.aulast=Han&rft.aufirst=Pauline&rft.date=2010-09-01&rft.volume=17&rft.issue=5&rft.spage=316&rft.isbn=&rft.btitle=&rft.title=Journal+of+Travel+Medicine&rft.issn=11951982&rft_id=info:doi/10.1111%2Fj.1708-8305.2010.00444.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-10-01 N1 - Number of references - 16 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - Travel; Injuries; income; prevention; risk taking; Children; Developing countries; attitudes DO - http://dx.doi.org/10.1111/j.1708-8305.2010.00444.x ER - TY - JOUR T1 - Well-being at work - overview and perspective AN - 867745940; 13674293 AB - This paper provides an overview of and perspective on the concept of well-being at work. Well-being is a term that reflects not only on one's health but satisfaction with work and life. Well-being is a summative concept that characterizes the quality of working lives, including occupational safety and health (OSH) aspects, and it may be a major determinant of productivity at the individual, enterprise and societal levels. Based on a review of the literature and a recent conference, we suggest a model linking workforce well-being, productivity, and population well-being. To appraise the validity of the model, we consider five questions: (i) is there a robust and usable definition of workplace well-being? (ii) have the variables that influence well-being been aptly described and can they be measured and used in risk assessments? (iii) what is the nature of evidence that well-being is linked to productivity? (iv) what is the state of knowledge on the effectiveness of interventions to promote workplace well-being? and (v) should interventions aimed at improving well-being at work focus on more than work-related factors?. JF - Scandinavian Journal of Work, Environment & Health AU - Schulte, P AU - Vainio, H AD - National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, 4676 Columbia Parkway, MS C-14, Cincinnati, Ohio 45226, USA, pschulte@cdc.gov Y1 - 2010/09// PY - 2010 DA - Sep 2010 SP - 422 EP - 429 VL - 36 IS - 5 SN - 0355-3140, 0355-3140 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Risk assessment KW - Conferences KW - intervention KW - Reviews KW - Occupational safety KW - R2 23080:Industrial and labor KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/867745940?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Scandinavian+Journal+of+Work%2C+Environment+%26+Health&rft.atitle=Well-being+at+work+-+overview+and+perspective&rft.au=Schulte%2C+P%3BVainio%2C+H&rft.aulast=Schulte&rft.aufirst=P&rft.date=2010-09-01&rft.volume=36&rft.issue=5&rft.spage=422&rft.isbn=&rft.btitle=&rft.title=Scandinavian+Journal+of+Work%2C+Environment+%26+Health&rft.issn=03553140&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-10-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Risk assessment; Conferences; Reviews; intervention; Occupational safety ER - TY - JOUR T1 - Prevention of invasive pneumococcal disease among HIV-infected adults in the era of childhood pneumococcal immunization AN - 807288929; 13921486 AB - Objective: Human immunodeficiency virus (HIV) infection and AIDS increase the risk of invasive pneumococcal disease (IPD). We evaluated IPD among HIV-infected adults over a 10-year period in the US to identify opportunities for prevention of IPD among HIV-infected adults. Design: IPD and HIV surveillance in seven population-based and laboratory-based Active Bacterial Core surveillance areas. Methods: IPD cases were adults 18-64 years old with pneumococcus isolated from a normally sterile site during 1998-2007. Isolates were serotyped using the Quellung reaction. HIV/AIDS status was determined by medical record review. We calculated incidence of IPD among adults with AIDS using national case-based surveillance data. Results: Of 13 812 IPD cases among 18-64-year-olds, 3236 (23%) occurred among HIV-infected adults (with or without AIDS) and 1313 (10%) occurred among the subset of HIV-infected adults with AIDS. Compared with the period (1998-1999) before childhood 7-valent pneumococcal conjugate vaccine (PCV7) introduction in the US, the overall incidence of IPD among adults with AIDS decreased 25% from 399 to 298 cases per 100 000 by 2007 (P = 0.008). In 2006-2007, 8, 39 and 55% of IPD cases among adults with AIDS were caused by serotypes included in the 7-valent PCV, 13-valent PCV and 23-valent pneumococcal polysaccharide vaccines, respectively. Conclusion: Sustained declines in IPD have occurred among adults with AIDS in the US, but incidence remained high 7 years after PCV7 introduction. More aggressive efforts, including HIV-prevention measures and the use of new PCVs in children and possibly HIV-infected adults, are necessary to further reduce IPD among HIV-infected adults. JF - AIDS AU - Cohen, AL AU - Harrison, L H AU - Farley, M M AU - Reingold, AL AU - Hadler, J AU - Schaffner, W AU - Lynfield, R AU - Thomas, A R AU - Campsmith, M AU - Li, J AU - Schuchat, A AU - Moore, M R AD - Centers for Disease Control and Prevention, 1600 Clifton Road NE, MS C-23, Atlanta, GA 30333, USA, dvj1@cdc.gov Y1 - 2010/09// PY - 2010 DA - Sep 2010 SP - 2253 EP - 2262 VL - 24 IS - 14 SN - 0269-9370, 0269-9370 KW - Microbiology Abstracts B: Bacteriology; Risk Abstracts; Health & Safety Science Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - vaccines KW - Acquired immune deficiency syndrome KW - Serotypes KW - Data processing KW - medical records KW - Children KW - Polysaccharides KW - Infection KW - Immunization KW - immunization KW - Streptococcus pneumoniae KW - Human immunodeficiency virus KW - Reviews KW - prevention KW - infection KW - Vaccines KW - V 22360:AIDS and HIV KW - J 02350:Immunology KW - F 06910:Microorganisms & Parasites KW - R2 23110:Psychological aspects KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/807288929?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS&rft.atitle=Prevention+of+invasive+pneumococcal+disease+among+HIV-infected+adults+in+the+era+of+childhood+pneumococcal+immunization&rft.au=Cohen%2C+AL%3BHarrison%2C+L+H%3BFarley%2C+M+M%3BReingold%2C+AL%3BHadler%2C+J%3BSchaffner%2C+W%3BLynfield%2C+R%3BThomas%2C+A+R%3BCampsmith%2C+M%3BLi%2C+J%3BSchuchat%2C+A%3BMoore%2C+M+R&rft.aulast=Cohen&rft.aufirst=AL&rft.date=2010-09-01&rft.volume=24&rft.issue=14&rft.spage=2253&rft.isbn=&rft.btitle=&rft.title=AIDS&rft.issn=02699370&rft_id=info:doi/10.1097%2FQAD.0b013e32833d46fd LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-11-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Acquired immune deficiency syndrome; Data processing; Serotypes; medical records; Vaccines; Infection; Polysaccharides; Children; Immunization; immunization; vaccines; Human immunodeficiency virus; Reviews; infection; prevention; Streptococcus pneumoniae DO - http://dx.doi.org/10.1097/QAD.0b013e32833d46fd ER - TY - JOUR T1 - Contraceptive sterilization use among married men in the United States: results from the male sample of the National Survey of Family Growth AN - 759316897; 13716873 AB - Surgical sterilization has many advantages. Previous information on prevalence and correlates was based on surveys of women. Study Design - We estimated the prevalence of vasectomy and tubal ligation of partners for male participants in the 2002 National Survey of Family Growth, a nationally representative survey of US residents aged 15-44 years. We identified factors associated with sterilizations using bivariate and multivariate techniques. Results - The findings revealed that 13.3% of married men reported having had a vasectomy and 13.8% reported tubal sterilization in their partners. Vasectomy increased with older age and greater number of biological children, non-Hispanic white ethnicity, having ever gone to a family planning clinic. Tubal sterilization use was more likely among men who had not attended college, those of older age and those with live births. Discussion - One in eight married men reported having vasectomies. Men who rely on vasectomies have a somewhat different profile than those whose partners have had tubal sterilizations. JF - Contraception AU - Anderson, John E AU - Warner, Lee AU - Jamieson, Denise J AU - Kissin, Dmitry M AU - Nangia, Ajay K AU - Macaluso, Maurizio AD - Women's Health and Fertility Branch, Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA, jea1@cdc.gov Y1 - 2010/09// PY - 2010 DA - Sep 2010 SP - 230 EP - 235 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 82 IS - 3 SN - 0010-7824, 0010-7824 KW - Sustainability Science Abstracts UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/759316897?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Contraception&rft.atitle=Contraceptive+sterilization+use+among+married+men+in+the+United+States%3A+results+from+the+male+sample+of+the+National+Survey+of+Family+Growth&rft.au=Anderson%2C+John+E%3BWarner%2C+Lee%3BJamieson%2C+Denise+J%3BKissin%2C+Dmitry+M%3BNangia%2C+Ajay+K%3BMacaluso%2C+Maurizio&rft.aulast=Anderson&rft.aufirst=John&rft.date=2010-09-01&rft.volume=82&rft.issue=3&rft.spage=230&rft.isbn=&rft.btitle=&rft.title=Contraception&rft.issn=00107824&rft_id=info:doi/10.1016%2Fj.contraception.2010.03.018 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-10-01 N1 - Last updated - 2011-12-14 DO - http://dx.doi.org/10.1016/j.contraception.2010.03.018 ER - TY - JOUR T1 - Is There Progress Toward Eliminating Racial/Ethnic Disparities in the Leading Causes of Death? AN - 758117873; 2010-616593 AB - Objectives. We examined changes in relative disparities between racial/ethnic populations for the five leading causes of death in the United States from 1990 to 2006. Methods. The study was based on age-adjusted death rates for four racial ethnic populations from 1990-1998 and 1999-2006. We compared the percent change in death rates over time between racial/ethnic populations to assess changes in relative differences. We also computed an index of disparity to assess changes in disparities relative to the most favorable group rate. Results. Except for stroke deaths from 1990 to 1998, relative disparities among racial/ethnic populations did not decline between 1990 and 2006. Disparities among racial/ethnic populations increased for heart disease deaths from 1999 to 2006, for chronic obstructive pulmonary disease deaths from 1990 to 1998, and for chronic lower respiratory disease deaths from 1999 to 2006. Conclusions. Deaths rates for the leading causes of death are generally declining; however, relative differences between racial/ethnic groups are not declining. The lack of reduction in relative differences indicates that little progress is being made toward the elimination of racial/ethnic disparities. Adapted from the source document. JF - Public Health Reports AU - KEppel, Kenneth G AU - Pearcy, Jeffrey N AU - Heron, Melonie P AD - Centers for Disease Control and Prevention, National Center for Health Statistics, 3311 Toledo Rd., Rm. 6313, Hyattsville, MD 20782; tel. 301-4584425; fax 301-4584038 Y1 - 2010/09// PY - 2010 DA - September 2010 SP - 689 EP - 697 PB - Oxford University Press, UK VL - 125 IS - 5 SN - 0033-3549, 0033-3549 KW - Population groups, population policy, and demographics - National, ethnic, and minority groups KW - Population groups, population policy, and demographics - Demography and census KW - Health conditions and policy - Diseases and disorders KW - United States KW - Mortality KW - Socioeconomic status KW - Heart disease KW - Ethnic groups KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/758117873?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Public+Health+Reports&rft.atitle=Is+There+Progress+Toward+Eliminating+Racial%2FEthnic+Disparities+in+the+Leading+Causes+of+Death%3F&rft.au=KEppel%2C+Kenneth+G%3BPearcy%2C+Jeffrey+N%3BHeron%2C+Melonie+P&rft.aulast=KEppel&rft.aufirst=Kenneth&rft.date=2010-09-01&rft.volume=125&rft.issue=5&rft.spage=689&rft.isbn=&rft.btitle=&rft.title=Public+Health+Reports&rft.issn=00333549&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2010-10-12 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Ethnic groups; Mortality; United States; Socioeconomic status; Heart disease ER - TY - JOUR T1 - Intimate Partner Aggression Perpetrated and Sustained by Male Afghanistan, Iraq, and Vietnam Veterans With and Without Posttraumatic Stress Disorder AN - 755128676; 13419261 AB - Veterans with posttraumatic stress disorder (PTSD) consistently evidence higher rates of intimate partner aggression perpetration than veterans without PTSD, but most studies have examined rates of aggression among Vietnam veterans several years after their deployment. The primary aim of this study was to examine partner aggression among male Afghanistan or Iraq veterans who served during Operation Enduring Freedom (OEF) and Operation Iraqi Freedom (OIF) and compare this aggression to that reported by Vietnam veterans with PTSD. Three groups were recruited, OEF/OIF veterans with PTSD (n = 27), OEF/OIF veterans without PTSD (n = 31), and Vietnam veterans with PTSD (n = 28). Though only a few comparisons reached significance, odds ratios suggested that male OEF/OIF veterans with PTSD were approximately 1.9 to 3.1 times more likely to perpetrate aggression toward their female partners and 1.6 to 6 times more likely to report experiencing female perpetrated aggression than the other two groups. Significant correlations among reports of violence perpetrated and sustained suggested many men may have been in mutually violent relationships. Taken together, these results suggest that partner aggression among Iraq and Afghanistan veterans with PTSD may be an important treatment consideration and target for prevention. JF - Journal of Interpersonal Violence AU - Teten, Andra L AU - Schumacher, Julie A AU - Taft, Casey T AU - Stanley, Melinda A AU - Kent, Thomas A AU - Bailey, Sara D AU - Dunn, Nancy Jo AU - White, Donna L AD - Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX,, South Central Mental Illness Research, Education, and Clinical Center (MIRECC), Houston, TX, Baylor College of Medicine, Houston, TX, ateten@cdc.gov Y1 - 2010/09// PY - 2010 DA - Sep 2010 SP - 1612 EP - 1630 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU UK VL - 25 IS - 9 SN - 0886-2605, 0886-2605 KW - Risk Abstracts UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/755128676?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Interpersonal+Violence&rft.atitle=Intimate+Partner+Aggression+Perpetrated+and+Sustained+by+Male+Afghanistan%2C+Iraq%2C+and+Vietnam+Veterans+With+and+Without+Posttraumatic+Stress+Disorder&rft.au=Teten%2C+Andra+L%3BSchumacher%2C+Julie+A%3BTaft%2C+Casey+T%3BStanley%2C+Melinda+A%3BKent%2C+Thomas+A%3BBailey%2C+Sara+D%3BDunn%2C+Nancy+Jo%3BWhite%2C+Donna+L&rft.aulast=Teten&rft.aufirst=Andra&rft.date=2010-09-01&rft.volume=25&rft.issue=9&rft.spage=1612&rft.isbn=&rft.btitle=&rft.title=Journal+of+Interpersonal+Violence&rft.issn=08862605&rft_id=info:doi/10.1177%2F0886260509354583 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-09-01 N1 - Last updated - 2011-12-14 DO - http://dx.doi.org/10.1177/0886260509354583 ER - TY - JOUR T1 - The polonium-210 public health assessment: the need for medical toxicology expertise in radiation terrorism events. AN - 749007855; 20499224 JF - Journal of medical toxicology : official journal of the American College of Medical Toxicology AU - Nemhauser, Jeffrey B AD - Radiation Studies Branch, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Mail Stop F-58, Atlanta, GA 30341, USA. jnemhauser@cdc.gov Y1 - 2010/09// PY - 2010 DA - September 2010 SP - 355 EP - 359 VL - 6 IS - 3 SN - 1556-9039, 1556-9039 KW - Polonium KW - DQY03U61EJ KW - Index Medicus KW - Humans KW - Radiation Injuries -- therapy KW - Radiation Monitoring KW - Terrorism KW - Public Health KW - Polonium -- poisoning KW - Toxicology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/749007855?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+medical+toxicology+%3A+official+journal+of+the+American+College+of+Medical+Toxicology&rft.atitle=The+polonium-210+public+health+assessment%3A+the+need+for+medical+toxicology+expertise+in+radiation+terrorism+events.&rft.au=Nemhauser%2C+Jeffrey+B&rft.aulast=Nemhauser&rft.aufirst=Jeffrey&rft.date=2010-09-01&rft.volume=6&rft.issue=3&rft.spage=355&rft.isbn=&rft.btitle=&rft.title=Journal+of+medical+toxicology+%3A+official+journal+of+the+American+College+of+Medical+Toxicology&rft.issn=15569039&rft_id=info:doi/10.1007%2Fs13181-010-0090-x LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-11-09 N1 - Date created - 2010-08-30 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1007/s13181-010-0090-x ER - TY - JOUR T1 - Federal agency support for healthy homes. AN - 748967453; 20689381 AB - Numerous studies have demonstrated that housing interventions such as addressing structural deficiencies or lack of safety devices improve health. These successes, coupled with reports by health care and housing professionals of other health and safety issues in homes that they were unable to address, have renewed interest in promoting health by addressing unhealthy housing conditions--but with a holistic approach. The Centers for Disease Control and Prevention, US Department of Housing and Urban Development, and US Environmental Protection Agency fund programs to improve indoor air and drinking water quality and prevent childhood lead poisoning. All of these programs offer valuable lessons for designing more integrated programs. The federal agencies and their grantees have demonstrated that interagency collaboration is essential for successful outcomes. However, the Department of Housing and Urban Development, the Environmental Protection Agency, and the Centers for Disease Control recognize that no individual agency has all of the necessary resources or expertise to formulate national programs and policies and implement a national healthy homes agenda. Thus, they have come together with the US Department of Health and Human Services, the Department of Energy, the US Department of Agriculture, the National Institute of Standards and Technology, the National Institute of Environmental Health Sciences, and the Office of the Surgeon General to form an interagency working group to ensure that vigorous, healthy homes policies are implemented at federal, national, and community levels. JF - Journal of public health management and practice : JPHMP AU - Brown, Mary Jean AU - Ammon, Matthew AU - Grevatt, Peter AD - Healthy Homes and Lead Poisoning Prevention Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA. mjb5@cdc.gov PY - 2010 SP - S90 EP - S93 VL - 16 IS - 5 Suppl KW - Health technology assessment KW - United States KW - Financing, Government KW - Cooperative Behavior KW - Humans KW - Safety Management KW - Housing -- standards KW - Government Agencies -- organization & administration KW - Federal Government UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/748967453?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+public+health+management+and+practice+%3A+JPHMP&rft.atitle=Federal+agency+support+for+healthy+homes.&rft.au=Brown%2C+Mary+Jean%3BAmmon%2C+Matthew%3BGrevatt%2C+Peter&rft.aulast=Brown&rft.aufirst=Mary&rft.date=2010-09-01&rft.volume=16&rft.issue=5+Suppl&rft.spage=S90&rft.isbn=&rft.btitle=&rft.title=Journal+of+public+health+management+and+practice+%3A+JPHMP&rft.issn=1550-5022&rft_id=info:doi/10.1097%2FPHH.0b013e3181ddf63d LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-12-18 N1 - Date created - 2010-08-06 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1097/PHH.0b013e3181ddf63d ER - TY - JOUR T1 - Factors associated with safe patient handling behaviors among critical care nurses AN - 1017971330; 16691636 AB - Background Patient handling is a major risk factor for musculoskeletal (MS) injury among nurses. The aims of the study were to describe nurses' work behaviors related to safe patient handling and identify factors influencing their safe work behaviors, including the use of lifting equipment. Methods A cross-sectional study using a mailed questionnaire with a nationwide random sample of 361 critical care nurses. Nurses reported on the physical, psychosocial, and organizational characteristics of their jobs and on their MS symptoms, risk perception, work behaviors, and demographics. Hierarchical multiple linear regression analyses were used to identify significant factors. Results More than half of participants had no lifting equipment on their unit, and 74% reported that they performed all patient lift or transfer tasks manually. Significant factors for safer work behavior included better safety climate, higher effort-reward imbalance, less overcommitment, greater social support, and day shift work. Physical workload, personal risk perception, or MS symptom experiences were not associated with safe work behavior. Conclusions Safe work behaviors are best understood as socio-cultural phenomena influenced by organizational, psychosocial, and job factors but, counter to extant theories of health behaviors, do not appear to be related to personal risk perception. Management efforts to improve working conditions and enhance safety culture in hospitals could prove to be crucial in promoting nurses' safe work behavior and reducing risk of MS injury. Am. J. Ind. Med. 53:886-897, 2010. ? 2010 Wiley-Liss, Inc. JF - American Journal of Industrial Medicine AU - Anp, Soo-Jeong Lee AU - Faan, Julia Faucett AU - Gillen, Marion AU - Krause, Niklas AU - Landry, Lynette AD - Department of Community Health Systems, School of Nursing, University of California at San Francisco, San Francisco, California, hgg8@cdc.gov Y1 - 2010/09// PY - 2010 DA - Sep 2010 SP - 886 EP - 897 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 53 IS - 9 SN - 1097-0274, 1097-0274 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Hospitals KW - Injuries KW - Medical personnel KW - Perception KW - lifting KW - musculoskeletal system KW - nursing KW - shift work KW - working conditions KW - H 1000:Occupational Safety and Health KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1017971330?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Factors+associated+with+safe+patient+handling+behaviors+among+critical+care+nurses&rft.au=Anp%2C+Soo-Jeong+Lee%3BFaan%2C+Julia+Faucett%3BGillen%2C+Marion%3BKrause%2C+Niklas%3BLandry%2C+Lynette&rft.aulast=Anp&rft.aufirst=Soo-Jeong&rft.date=2010-09-01&rft.volume=53&rft.issue=9&rft.spage=886&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=10970274&rft_id=info:doi/10.1002%2Fajim.20843 L2 - http://onlinelibrary.wiley.com/doi/10.1002/ajim.20843/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2012-06-01 N1 - SubjectsTermNotLitGenreText - shift work; Injuries; Perception; lifting; nursing; musculoskeletal system; working conditions; Medical personnel; Hospitals DO - http://dx.doi.org/10.1002/ajim.20843 ER - TY - JOUR T1 - Industry-wide medical surveillance of California flavor manufacturing workers: Cross-sectional results AN - 1017971264; 16691633 AB - Background Two cases of bronchiolitis obliterans in flavor manufacturing workers prompted California health and labor agencies to initiate industry-wide surveillance. Methods Companies' physicians submitted cross-sectional questionnaire and spirometry data for 467 workers in 16 workplaces. We compared prevalence ratios of respiratory symptoms, diagnoses, and abnormal spirometry to a general population sample. We calculated odds ratios for risk factors for spirometric obstructive abnormality. Results Flavoring workers were 2.7 times more likely than the general population to have severe airways obstruction. Risk factors identified for 18 cases with obstruction from six companies included younger age, Hispanic ethnicity, liquid and powder production work, greater company diacetyl usage, and having a coworker with obstruction. Severity of obstruction was related to tenure. At least 12 workers had probable occupational fixed airways obstruction. Conclusions The flavoring industry risk of severe lung disease justifies lowering flavoring exposures and medical screening for secondary prevention until worker safety is demonstrated. Am. J. Ind. Med. 53:857-865, 2010. ? 2010 Wiley-Liss, Inc. JF - American Journal of Industrial Medicine AU - Kim, Thomas J AU - Materna, Barbara L AU - Prudhomme, Janice C AU - Fedan, Kathleen B AU - Enright, Paul L AU - Sahakian, Nancy M AU - Windham, Gayle C AU - Kreiss, Kathleen AD - Division of Environmental and Occupational Disease Control, California Department of Public Health (CDPH), Richmond, California, kkreiss@cdc.gov Y1 - 2010/09// PY - 2010 DA - Sep 2010 SP - 857 EP - 865 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 53 IS - 9 SN - 1097-0274, 1097-0274 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Age KW - Ethnic groups KW - Lung KW - Risk factors KW - prevention KW - USA, California KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1017971264?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Industry-wide+medical+surveillance+of+California+flavor+manufacturing+workers%3A+Cross-sectional+results&rft.au=Kim%2C+Thomas+J%3BMaterna%2C+Barbara+L%3BPrudhomme%2C+Janice+C%3BFedan%2C+Kathleen+B%3BEnright%2C+Paul+L%3BSahakian%2C+Nancy+M%3BWindham%2C+Gayle+C%3BKreiss%2C+Kathleen&rft.aulast=Kim&rft.aufirst=Thomas&rft.date=2010-09-01&rft.volume=53&rft.issue=9&rft.spage=857&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=10970274&rft_id=info:doi/10.1002%2Fajim.20858 L2 - http://onlinelibrary.wiley.com/doi/10.1002/ajim.20858/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2012-06-01 N1 - SubjectsTermNotLitGenreText - Age; Lung; Risk factors; prevention; Ethnic groups; USA, California DO - http://dx.doi.org/10.1002/ajim.20858 ER - TY - JOUR T1 - Characterization of the antiviral and inflammatory responses against Nipah virus in endothelial cells and neurons AN - 754540135; 13253795 AB - Nipah virus (NiV) is a highly pathogenic paramyxovirus which causes fatal encephalitis in up to 75% of infected humans. Endothelial cells and neurons are important cellular targets in the pathogenesis of this disease. In this study, viral replication and the innate immune responses to NiV in these cell types were measured. NiV infected endothelial cells generated a functionally robust IFN-b response, which correlated with localization of the NiV W protein to the cytoplasm. There was no antiviral response detected in infected neuronal cells. NiV infection of endothelial cells induced a significant increase in secreted inflammatory chemokines, which corresponded with the increased ability of infected cell supernatants to induce monocyte and T-lymphocyte chemotaxis. These results suggest that pro-inflammatory chemokines produced by NiV infected primary endothelial cells in vitro is consistent with the prominent vasculitis observed in infections, and provide initial molecular insights into the pathogenesis of NiV in physiologically relevant cells types. JF - Virology AU - Lo, Michael K AU - Miller, David AU - Aljofan, Mohammad AU - Mungall, Bruce A AU - Rollin, Pierre E AU - Bellini, William J AU - Rota, Paul A AD - Measles, Mumps, Rubella, and Herpesvirus Laboratory Branch, Centers for Disease Control and Prevention, Mailstop C-22, 1600 Clifton Road, Atlanta, GA 30333, USA, mko2@cdc.gov Y1 - 2010/08/15/ PY - 2010 DA - 2010 Aug 15 SP - 78 EP - 88 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 404 IS - 1 SN - 0042-6822, 0042-6822 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; CSA Neurosciences Abstracts; Immunology Abstracts; Virology & AIDS Abstracts; Chemoreception Abstracts KW - Chemokines KW - W protein KW - Vasculitis KW - Replication KW - Paramyxovirus KW - Infection KW - Chemotaxis KW - Encephalitis KW - Inflammation KW - b-Interferon KW - Endothelial cells KW - Neurons KW - Cytoplasm KW - Nipah virus KW - Lymphocytes T KW - Immune response KW - Monocytes KW - R 18003:Chemotaxis KW - A 01340:Antibiotics & Antimicrobials KW - V 22350:Immunology KW - N3 11007:Neurobiology KW - F 06910:Microorganisms & Parasites UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754540135?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Virology&rft.atitle=Characterization+of+the+antiviral+and+inflammatory+responses+against+Nipah+virus+in+endothelial+cells+and+neurons&rft.au=Lo%2C+Michael+K%3BMiller%2C+David%3BAljofan%2C+Mohammad%3BMungall%2C+Bruce+A%3BRollin%2C+Pierre+E%3BBellini%2C+William+J%3BRota%2C+Paul+A&rft.aulast=Lo&rft.aufirst=Michael&rft.date=2010-08-15&rft.volume=404&rft.issue=1&rft.spage=78&rft.isbn=&rft.btitle=&rft.title=Virology&rft.issn=00426822&rft_id=info:doi/10.1016%2Fj.virol.2010.05.005 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Chemokines; Vasculitis; W protein; Replication; Infection; Chemotaxis; Encephalitis; Inflammation; Endothelial cells; b-Interferon; Cytoplasm; Neurons; Lymphocytes T; Monocytes; Immune response; Nipah virus; Paramyxovirus DO - http://dx.doi.org/10.1016/j.virol.2010.05.005 ER - TY - JOUR T1 - Two-Year Follow-Up of Sexual Behavior Among HIV-Uninfected Household Members of Adults Taking Antiretroviral Therapy in Uganda: No Evidence of Disinhibition AN - 853480118; 13749224 AB - This paper examines HIV risk behavior among HIV-uninfected adults living with people taking antiretroviral therapy (ART) in Uganda. A prospective cohort of 455 HIV-uninfected non-spousal household members of ART patients receiving home-based AIDS care was enrolled. Sexual behavior, HIV risk perceptions, AIDS-related anxiety, and the perception that AIDS is curable were assessed at baseline, 6, 12 and 24months. Generalized linear mixture models were used to model risk behavior over time and to identify behavioral correlates. Overall, risky sex decreased from 29% at baseline to 15% at 24-months. Among women, risky sex decreased from 31% at baseline to 10% at 6months and 15% at 24months. Among men, risky sex decreased from 30% at baseline to 8% at 6months and 13% at 24months. Perceiving HIV/AIDS as curable and lower AIDS-related anxiety were independently associated with risky sex. No evidence of behavioral disinhibition was observed. Concerns regarding behavioral disinhibition should not slow down efforts to increase ART access in Africa. JF - AIDS and Behavior AU - Bechange, Stevens AU - Bunnell, Rebecca AU - Awor, Anna AU - Moore, David AU - King, Rachel AU - Mermin, Jonathan AU - Tappero, Jordan AU - Khana, Kenneth AU - Bartholow, Bradford AD - CDC-Uganda, Global AIDS Program, National Center for HIV, Viral Hepatitis, STD and TB Prevention, Uganda Virus Research Institute, Centers for Disease Control and Prevention (CDC), P.O. Box 49, 51-59 Nakiwogo Road, Entebbe, Uganda, bechanges@ug.cdc.gov Y1 - 2010/08// PY - 2010 DA - Aug 2010 SP - 816 EP - 823 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 14 IS - 4 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Risk Abstracts KW - sexual behavior KW - Acquired immune deficiency syndrome KW - Anxiety KW - antiretroviral therapy KW - Uganda KW - Sexual behavior KW - Models KW - households KW - Human immunodeficiency virus KW - Perception KW - antiretroviral agents KW - Africa KW - Sex KW - V 22360:AIDS and HIV KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/853480118?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Two-Year+Follow-Up+of+Sexual+Behavior+Among+HIV-Uninfected+Household+Members+of+Adults+Taking+Antiretroviral+Therapy+in+Uganda%3A+No+Evidence+of+Disinhibition&rft.au=Bechange%2C+Stevens%3BBunnell%2C+Rebecca%3BAwor%2C+Anna%3BMoore%2C+David%3BKing%2C+Rachel%3BMermin%2C+Jonathan%3BTappero%2C+Jordan%3BKhana%2C+Kenneth%3BBartholow%2C+Bradford&rft.aulast=Bechange&rft.aufirst=Stevens&rft.date=2010-08-01&rft.volume=14&rft.issue=4&rft.spage=816&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-008-9481-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-02-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Acquired immune deficiency syndrome; Anxiety; Perception; antiretroviral therapy; Sexual behavior; Models; Sex; sexual behavior; households; Human immunodeficiency virus; antiretroviral agents; Africa; Uganda DO - http://dx.doi.org/10.1007/s10461-008-9481-2 ER - TY - JOUR T1 - Mortality and Health among Internally Displaced Persons in Western Kenya following Post-Election Violence, 2008: Novel Use of Demographic Surveillance AN - 758116865; 2010-625644 AB - Objective: To evaluate mortality and morbidity among internally displaced persons (IDPs) who relocated in a demographic surveillance system (DSS) area in western Kenya following post-election violence. Methods: In 2007, 204 000 individuals lived in the DSS area, where field workers visit households every 4 months to record migrations, births and deaths. We collected data on admissions among children 5 years (53%) than among regular DSS residents (25-29%) (P < 0.001). Internally displaced children < 5 years of age did not die at higher rates than resident children but were hospitalized at higher rates (RR: 2.95; 95% CI: 2.44-3.58). Conclusion: HIV-infected internally displaced adults in conflict-ridden parts of Africa are at increased risk of HIV-related death. Relief efforts should extend to IDPs who have relocated outside IDP camps, particularly if afflicted with HIV infection or other chronic conditions. Adapted from the source document. JF - Bulletin of the World Health Organization AU - Feikin, Daniel R AU - Adazu, Kubaje AU - Obor, David AU - Ogwang, Sheila AU - Vulule, John AU - Hamel, Mary J AU - Laserson, Kayla AD - Kenya Medical Research Instit/Centers Disease Control & Prevention/Research/Public Health Collaboration, Kisumu dfeikin@cdc.gov Y1 - 2010/08// PY - 2010 DA - August 2010 SP - 601 EP - 608 PB - World Health Organization, Geneva, Switzerland VL - 88 IS - 8 SN - 0042-9686, 0042-9686 KW - Population groups, population policy, and demographics - Demography and census KW - Health conditions and policy - Health and health policy KW - Population groups, population policy, and demographics - Migrants and migration KW - Politics - Political dissent and internal conflict KW - Politics - Elections and voting KW - Health conditions and policy - Diseases and disorders KW - Health conditions and policy - Hospitals and other health care facilities KW - Health conditions and policy - Medicine and health care KW - Autopsy KW - Mortality KW - Elections KW - Kenya KW - Human immunodeficiency virus KW - Political violence KW - Internally displaced persons KW - Migration KW - Hospitals KW - Public health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/758116865?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Bulletin+of+the+World+Health+Organization&rft.atitle=Mortality+and+Health+among+Internally+Displaced+Persons+in+Western+Kenya+following+Post-Election+Violence%2C+2008%3A+Novel+Use+of+Demographic+Surveillance&rft.au=Feikin%2C+Daniel+R%3BAdazu%2C+Kubaje%3BObor%2C+David%3BOgwang%2C+Sheila%3BVulule%2C+John%3BHamel%2C+Mary+J%3BLaserson%2C+Kayla&rft.aulast=Feikin&rft.aufirst=Daniel&rft.date=2010-08-01&rft.volume=88&rft.issue=8&rft.spage=601&rft.isbn=&rft.btitle=&rft.title=Bulletin+of+the+World+Health+Organization&rft.issn=00429686&rft_id=info:doi/10.2471%2FBLT.09.069732 LA - English DB - PAIS Index N1 - Date revised - 2010-10-12 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Mortality; Public health; Internally displaced persons; Kenya; Political violence; Elections; Migration; Human immunodeficiency virus; Hospitals; Autopsy DO - http://dx.doi.org/10.2471/BLT.09.069732 ER - TY - JOUR T1 - EXAMINING HIV INFECTION AMONG MALE SEX WORKERS IN BANGKOK, THAILAND: A COMPARISON OF PARTICIPANTS RECRUITED AT ENTERTAINMENT AND STREET VENUES AN - 754889012; 13450921 AB - HIV prevalence and associated factors were examined among male sex workers (MSWs, N = 414) in Bangkok, Thailand. Cross-sectional venue-day-time sampling was used to collect data in entertainment and street venues. Chi-square and logistic regression were used to identify HIV risk factors. HIV prevalence was 18.8% overall, but differences were found between MSW recruited in entertainment and street venues. Significant relationships were found between several demographic, behavioral, exposure to HIV prevention, and other characteristics, and recruitment location. In multivariate analyses, being sexually attracted to men was significantly associated with HIV infection among both groups of sex workers. In addition, among street-based sex workers, not having had sex with a woman in the past 3 months, having ever had a sexually transmitted disease symptom, and not having a friend to talk to about personal problems were significantly associated with HIV infection. JF - AIDS Education and Prevention AU - Toledo, CA AU - Varangrat, A AU - Wimolsate, W AU - Chemnasiri, T AU - Phanuphak, P AU - Kalayil, E J AU - McNicholl, J AU - Karuchit, S AU - Kengkarnrua, K AU - van Griensven, F AD - Global AIDS Program, Centers for Disease Control and Prevention, 1600 Clifton Rd., Mailstop E59, Atlanta, GA 30333, USA, ctoledo@cdc.gov Y1 - 2010/08// PY - 2010 DA - Aug 2010 SP - 299 EP - 311 VL - 22 IS - 4 SN - 0899-9546, 0899-9546 KW - Risk Abstracts; Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - demography KW - Acquired immune deficiency syndrome KW - Data processing KW - Sexually-transmitted diseases KW - Recruitment KW - males KW - Prostitution KW - Thailand, Chacoengsao Prov., Bangkok KW - Infection KW - Demography KW - Workers KW - Education KW - Human immunodeficiency virus KW - Multivariate analysis KW - Risk factors KW - infection KW - prevention KW - recruitment KW - Sampling KW - sexually transmitted diseases KW - Sex KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754889012?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+Education+and+Prevention&rft.atitle=EXAMINING+HIV+INFECTION+AMONG+MALE+SEX+WORKERS+IN+BANGKOK%2C+THAILAND%3A+A+COMPARISON+OF+PARTICIPANTS+RECRUITED+AT+ENTERTAINMENT+AND+STREET+VENUES&rft.au=Toledo%2C+CA%3BVarangrat%2C+A%3BWimolsate%2C+W%3BChemnasiri%2C+T%3BPhanuphak%2C+P%3BKalayil%2C+E+J%3BMcNicholl%2C+J%3BKaruchit%2C+S%3BKengkarnrua%2C+K%3Bvan+Griensven%2C+F&rft.aulast=Toledo&rft.aufirst=CA&rft.date=2010-08-01&rft.volume=22&rft.issue=4&rft.spage=299&rft.isbn=&rft.btitle=&rft.title=AIDS+Education+and+Prevention&rft.issn=08999546&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-09-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Demography; Workers; Data processing; Sexually-transmitted diseases; Multivariate analysis; Risk factors; Recruitment; Prostitution; Sampling; Infection; Sex; demography; Education; Acquired immune deficiency syndrome; Human immunodeficiency virus; prevention; infection; recruitment; males; sexually transmitted diseases; Thailand, Chacoengsao Prov., Bangkok ER - TY - JOUR T1 - Who's Responsible? Correlates of Partner Involvement in Contraceptive Decision Making AN - 754881588; 13406747 AB - Objectives - Researchers have begun looking at joint responsibility for contraceptive decision making as a mechanism to increase effective contraceptive use. This analysis identifies correlates of partner involvement in contraceptive decision making. Methods - Participants were first-time users of either oral contraceptives or Depo-Provera recruited from 10 family planning clinics in Texas (n = 481). Participants completed a self-administered questionnaire that was available in both English and Spanish. Chi-square statistics were used to compare demographics, relationship characteristics, and condom use before and after initiation of the new hormonal method by who is responsible for birth control use. Characteristics that were significant in bivariate testing were then included in a multivariate logistic regression model. Results - Forty-five percent of women reported sole responsibility for contraceptive use and 55% reported joint responsibility with their partners. In multivariate models, consistent condom use before and after the initiation of hormonal contraception and duration of sexual activity with main partner for less than 2 years were associated with increased likelihood of joint responsibility for contraceptive decision making. Women whose partners were classified as high risk had reduced the odds of joint responsibility for contraceptive decision making. Conclusion - Women at increased risk for sexually transmitted diseases (high-risk partners) and their partners may represent a target population for interventions aimed at increasing joint responsibility for contraception use. Continuous engagement in contraceptive decision making among long-term couples should also be encouraged. JF - Women's Health Issues AU - Cox, Shanna AU - Posner, Samuel F AU - Sangi-Haghpeykar, Haleh AD - Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia, cio8@cdc.gov Y1 - 2010/08// PY - 2010 DA - Aug 2010 SP - 254 EP - 259 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 20 IS - 4 SN - 1049-3867, 1049-3867 KW - Health & Safety Science Abstracts; Risk Abstracts KW - demography KW - family planning KW - contraceptives KW - intervention KW - condoms KW - USA, Texas KW - sexually transmitted diseases KW - responsibility KW - R2 23060:Medical and environmental health KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754881588?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Women%27s+Health+Issues&rft.atitle=Who%27s+Responsible%3F+Correlates+of+Partner+Involvement+in+Contraceptive+Decision+Making&rft.au=Cox%2C+Shanna%3BPosner%2C+Samuel+F%3BSangi-Haghpeykar%2C+Haleh&rft.aulast=Cox&rft.aufirst=Shanna&rft.date=2010-08-01&rft.volume=20&rft.issue=4&rft.spage=254&rft.isbn=&rft.btitle=&rft.title=Women%27s+Health+Issues&rft.issn=10493867&rft_id=info:doi/10.1016%2Fj.whi.2010.03.006 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-09-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - demography; family planning; intervention; condoms; sexually transmitted diseases; responsibility; contraceptives; USA, Texas DO - http://dx.doi.org/10.1016/j.whi.2010.03.006 ER - TY - JOUR T1 - Prevalence of highly active adults - Behavioral risk factor surveillance system, 2007 AN - 754880082; 13399163 AB - The 2008 Physical Activity Guidelines for Americans (2008 Guidelines) included a novel aerobic physical activity standard, in excess of minimum standards, for more extensive health benefits (> 300 minutes/week of moderate-intensity, 150 minutes/week of vigorous-intensity, or an equivalent combination). Prevalence estimates among US states have yet to be described for this new standard. Methods - Respondents self-reported physical activity in the 2007 Behavioral Risk Factor Surveillance System was used (n = 398,397). Total weekly aerobic activity was calculated for each respondent and 2008 Guidelines standards guided classification. Results - In 2007, 43.5% (95% CI: 43.1%-43.8%) of adults met the new 2008 Guidelines standard and were classified as highly active (male, 48.3%; female, 38.9%). Linear patterns were noted by age and education, where younger age and higher levels of education had a higher proportion of highly active. Non-Hispanic whites (45.7%) had a significantly higher proportion of highly active compared with non-Hispanic blacks (37.5%) and Hispanics (37.6%). Variations in estimates were noted among those categorized as sufficiently active, insufficiently active, and inactive. Conclusion - More than half of 2007 Behavioral Risk Factor Surveillance System respondents did not meet the new 2008 Guidelines standard. Aerobic activity levels commensurate with more extensive health benefits should be encouraged among US adults. JF - Preventive Medicine AU - Adabonyan, Ife AU - Loustalot, Fleetwood AU - Kruger, Judy AU - Carlson, Susan A AU - Fulton, Janet E AD - Division of Nutrition, Physical Activity and Obesity, Centers for Disease Control and Prevention, 4770 Buford Hwy NE, K-46, Atlanta, GA 30341-3717, United States, floustalot@cdc.gov Y1 - 2010/08// PY - 2010 DA - Aug 2010 SP - 139 EP - 143 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 51 IS - 2 SN - 0091-7435, 0091-7435 KW - Risk Abstracts KW - Age KW - Education KW - guidelines KW - classification KW - physical activity KW - Ethnic groups KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754880082?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Preventive+Medicine&rft.atitle=Prevalence+of+highly+active+adults+-+Behavioral+risk+factor+surveillance+system%2C+2007&rft.au=Adabonyan%2C+Ife%3BLoustalot%2C+Fleetwood%3BKruger%2C+Judy%3BCarlson%2C+Susan+A%3BFulton%2C+Janet+E&rft.aulast=Adabonyan&rft.aufirst=Ife&rft.date=2010-08-01&rft.volume=51&rft.issue=2&rft.spage=139&rft.isbn=&rft.btitle=&rft.title=Preventive+Medicine&rft.issn=00917435&rft_id=info:doi/10.1016%2Fj.ypmed.2010.05.014 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-09-01 N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - Age; Education; guidelines; classification; physical activity; Ethnic groups DO - http://dx.doi.org/10.1016/j.ypmed.2010.05.014 ER - TY - JOUR T1 - Improved Molecular Detection of Angiostrongylus cantonensis in Mollusks and Other Environmental Samples with a Species-Specific Internal Transcribed Spacer 1-Based TaqMan Assay AN - 754537297; 13245682 AB - Angiostrongylus cantonensis is the most common cause of human eosinophilic meningitis. Humans become infected by ingesting food items contaminated with third-stage larvae that develop in mollusks. We report the development of a real-time PCR assay for the species-specific identification of A. cantonensis in mollusk tissue. JF - Applied and Environmental Microbiology AU - Qvarnstrom, Yvonne AU - Aramburu da Silva, Ana Cristina AU - Teem, John L AU - Hollingsworth, Robert AU - Bishop, Henry AU - Graeff-Teixeira, Carlos AU - da Silva, Alexandre J AD - Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Public Health Service, U.S. Department of Health and Human Services, Atlanta, Georgia, abs8@cdc.gov Y1 - 2010/08// PY - 2010 DA - Aug 2010 SP - 5287 EP - 5289 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 76 IS - 15 SN - 0099-2240, 0099-2240 KW - Microbiology Abstracts A: Industrial & Applied Microbiology KW - Food contamination KW - Spacer KW - Angiostrongylus cantonensis KW - A 01340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754537297?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Improved+Molecular+Detection+of+Angiostrongylus+cantonensis+in+Mollusks+and+Other+Environmental+Samples+with+a+Species-Specific+Internal+Transcribed+Spacer+1-Based+TaqMan+Assay&rft.au=Qvarnstrom%2C+Yvonne%3BAramburu+da+Silva%2C+Ana+Cristina%3BTeem%2C+John+L%3BHollingsworth%2C+Robert%3BBishop%2C+Henry%3BGraeff-Teixeira%2C+Carlos%3Bda+Silva%2C+Alexandre+J&rft.aulast=Qvarnstrom&rft.aufirst=Yvonne&rft.date=2010-08-01&rft.volume=76&rft.issue=15&rft.spage=5287&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/10.1128%2FAEM.00546-10 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Spacer; Angiostrongylus cantonensis DO - http://dx.doi.org/10.1128/AEM.00546-10 ER - TY - JOUR T1 - Mutant Selection Window and Characterization of Allelic Diversity for Ciprofloxacin-Resistant Mutants of Rhodococcus equi AN - 754532754; 13233370 AB - The mutant prevention concentration (MPC) for ciprofloxacin was determined for two Rhodococcus equi strains. The MPC for both strains was 32 kg/ml, which is above the peak serum concentration of ciprofloxacin obtainable by oral administration in humans. Nine single nucleotide changes corresponding to eight amino acid substitutions in the quinolone resistance-determining regions of DNA gyrase subunits A and B were characterized. Only mutants with amino acid changes in Ser-83 of GyrA were highly resistant (64 kg/ml). Our results suggest that ciprofloxacin monotherapy against R. equi infection may result in the emergence of ciprofloxacin-resistant mutants. JF - Antimicrobial Agents & Chemotherapy AU - Niwa, Hidekazu AU - Lasker, Brent A AD - Microbiology Division, Epizootic Research Center, Equine Research Institute, Japan Racing Association, Shimotsuke, Japan, blasker@cdc.gov Y1 - 2010/08// PY - 2010 DA - Aug 2010 SP - 3520 EP - 3523 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 54 IS - 8 SN - 0066-4804, 0066-4804 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology KW - Ciprofloxacin KW - Amino acid substitution KW - Quinolones KW - DNA topoisomerase KW - Oral administration KW - Genetic diversity KW - Rhodococcus equi KW - Infection KW - Nucleotides KW - Amino acid sequence KW - A 01340:Antibiotics & Antimicrobials KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754532754?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Mutant+Selection+Window+and+Characterization+of+Allelic+Diversity+for+Ciprofloxacin-Resistant+Mutants+of+Rhodococcus+equi&rft.au=Niwa%2C+Hidekazu%3BLasker%2C+Brent+A&rft.aulast=Niwa&rft.aufirst=Hidekazu&rft.date=2010-08-01&rft.volume=54&rft.issue=8&rft.spage=3520&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.01670-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Ciprofloxacin; Amino acid substitution; Quinolones; Oral administration; DNA topoisomerase; Genetic diversity; Infection; Nucleotides; Amino acid sequence; Rhodococcus equi DO - http://dx.doi.org/10.1128/AAC.01670-09 ER - TY - JOUR T1 - Generation of a dual RT Env SHIV that is infectious in rhesus macaques AN - 746235943; 13191734 AB - AbstractBackground The best current animal model for HIV infection and evaluation of antiviral compounds is the Simian-human immunodeficiency virus (SHIV)-macaque system. There are multiple recombinant SHIVs available, but these viruses have limitations in evaluating combination drug strategies for prevention. Drug combinations that target reverse transcriptase (RT, either nRTI or nnRTI) and envelope (entry or fusion inhibitors) have to be tested separately, which does not permit the assessment of additive, synergistic, or antagonistic effects of ARV combinations. We describe construction of a dual SHIV containing both HIV RT and a CCR5-specific HIV envelope gene in a simian immunodeficiency virus backbone.Methods The RT Env SHIV molecular clone was constructed using RT SHIV and SHIV162p3 sequences as templates to generate RT Env SHIV. RT Env SHIV was expanded in vitro in CD8-depleted macaque peripheral blood mononuclear cells (PBMC). Recombinant virus was used to infect a rhesus macaque (4.3 x 104 tissue culture infectious dose [TCID50], intravenously [IV]). A second passage in a macaque by IV transfer of 10 ml of blood obtained from the first infection was also done. The in vivo adapted virus stock from these macaques was used to produce high titer stocks in vitro and used to rectally infect an additional macaque.Results Peak viral load reached 6 x 105 vRNA copies-ml in plasma in both IV-exposed macaques and remained detectable in the one animal for 16 weeks after infection. A viral stock (1.68 x 104 TCID50) derived from the second macaque passage has been produced in CD8-depleted rhesus PBMC and was successfully used to demonstrate mucosal transmission. The resulting RT Env SHIV retained the sensitivity to HIV RT and entry inhibitors of its parental viruses.Conclusions The objective of this study was to develop and characterize a SHIV recombinant virus for evaluating the efficacy of ART and microbicide products that target both HIV RT and-or Env-mediated entry. RT Env SHIV can productively infect macaques by both the IV and mucosal route, making it a valuable tool for transmission studies. JF - Journal of Medical Primatology AU - Smith, James M AU - Dauner, Allison AU - Li, Bin AU - Srinivasan, Priya AU - Mitchell, James AU - Hendry, Michael AU - Ellenberger, Dennis AU - Butera, Sal AU - Otten, Ron A AD - Laboratory Branch, Division of HIV-AIDS Prevention, National Center for HIV, STD, TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA, ajo9@cdc.gov Y1 - 2010/08// PY - 2010 DA - Aug 2010 SP - 213 EP - 223 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 USA VL - 39 IS - 4 SN - 0047-2565, 0047-2565 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Virology & AIDS Abstracts KW - Animal models KW - Antiviral agents KW - CD8 antigen KW - Drug development KW - Envelope gene KW - Envelopes KW - Infection KW - Mucosa KW - Peripheral blood mononuclear cells KW - RNA-directed DNA polymerase KW - Tissue culture KW - antiretroviral therapy KW - microbicides KW - Simian/human immunodeficiency virus KW - Human immunodeficiency virus KW - Macaca mulatta KW - Simian immunodeficiency virus KW - A 01340:Antibiotics & Antimicrobials KW - V 22360:AIDS and HIV UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/746235943?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Medical+Primatology&rft.atitle=Generation+of+a+dual+RT+Env+SHIV+that+is+infectious+in+rhesus+macaques&rft.au=Smith%2C+James+M%3BDauner%2C+Allison%3BLi%2C+Bin%3BSrinivasan%2C+Priya%3BMitchell%2C+James%3BHendry%2C+Michael%3BEllenberger%2C+Dennis%3BButera%2C+Sal%3BOtten%2C+Ron+A&rft.aulast=Smith&rft.aufirst=James&rft.date=2010-08-01&rft.volume=39&rft.issue=4&rft.spage=213&rft.isbn=&rft.btitle=&rft.title=Journal+of+Medical+Primatology&rft.issn=00472565&rft_id=info:doi/10.1111%2Fj.1600-0684.2010.00434.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-07-01 N1 - Number of references - 39 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - Mucosa; antiretroviral therapy; Animal models; Drug development; CD8 antigen; Tissue culture; Infection; Peripheral blood mononuclear cells; Envelopes; Antiviral agents; Envelope gene; RNA-directed DNA polymerase; microbicides; Human immunodeficiency virus; Simian/human immunodeficiency virus; Macaca mulatta; Simian immunodeficiency virus DO - http://dx.doi.org/10.1111/j.1600-0684.2010.00434.x ER - TY - JOUR T1 - Likelihood-based methods for estimating the association between a health outcome and left- or interval-censored longitudinal exposure data AN - 1093462059; 16691256 AB - The Michigan Female Health Study (MFHS) conducted research focusing on reproductive health outcomes among women exposed to polybrominated biphenyls (PBBs). In the work presented here, the available longitudinal serum PBB exposure measurements are used to obtain predictions of PBB exposure for specific time points of interest via random effects models. In a two-stage approach, a prediction of the PBB exposure is obtained and then used in a second-stage health outcome model. This paper illustrates how a unified approach, which links the exposure and outcome in a joint model, provides an efficient adjustment for covariate measurement error. We compare the use of empirical Bayes predictions in the two-stage approach with results from a joint modeling approach, with and without an adjustment for left- and interval-censored data. The unified approach with the adjustment for left- and interval-censored data resulted in little bias and near-nominal confidence interval coverage in both the logistic and linear model setting. Published in 2010 by John Wiley & Sons, Ltd. JF - Statistics in Medicine AU - Wannemuehler, Kathleen A AU - Lyles, Robert H AU - Manatunga, Amita K AU - Terrell, Metrecia L AU - Marcus, Michele AD - Division of Foodborne, Bacterial and Mycotic Diseases, National Center for Zoonotic, Vectorborne and Enteric Diseases, Centers for Disease Control and Prevention, Atlanta, GA, U.S.A., kpw9@cdc.gov Y1 - 2010/07/20/ PY - 2010 DA - 2010 Jul 20 SP - 1661 EP - 1672 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 29 IS - 16 SN - 1097-0258, 1097-0258 KW - Health & Safety Science Abstracts KW - Prediction KW - Reproduction KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1093462059?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Statistics+in+Medicine&rft.atitle=Likelihood-based+methods+for+estimating+the+association+between+a+health+outcome+and+left-+or+interval-censored+longitudinal+exposure+data&rft.au=Wannemuehler%2C+Kathleen+A%3BLyles%2C+Robert+H%3BManatunga%2C+Amita+K%3BTerrell%2C+Metrecia+L%3BMarcus%2C+Michele&rft.aulast=Wannemuehler&rft.aufirst=Kathleen&rft.date=2010-07-20&rft.volume=29&rft.issue=16&rft.spage=1661&rft.isbn=&rft.btitle=&rft.title=Statistics+in+Medicine&rft.issn=10970258&rft_id=info:doi/10.1002%2Fsim.3905 L2 - http://onlinelibrary.wiley.com/doi/10.1002/sim.3905/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-10-01 N1 - Last updated - 2013-06-28 N1 - SubjectsTermNotLitGenreText - Prediction; Reproduction DO - http://dx.doi.org/10.1002/sim.3905 ER - TY - JOUR T1 - When Stepparents Adopt: Demographic, Health and Health Care Characteristics of Adopted Children, Stepchildren, and Adopted Stepchildren AN - 862780906 AB - This article compares adopted stepchildren to both stepchildren and adopted children to determine which group adopted stepchildren more closely resemble. Adopted stepchildren more closely resemble stepchildren in terms of the child's demographic characteristics, but more closely resemble adopted children in terms of household socioeconomic characteristics. Stepchildren tend to have better health than adopted children, and adopted children tend to have better health care than stepchildren. Adopted stepchildren are more like stepchildren with respect to health and more like adopted children with respect to health care although this last finding is diluted once estimates are adjusted for demographic and socioeconomic characteristics. Adapted from the source document. JF - Adoption Quarterly AU - Bramlett, Matthew D AD - National Center Health Statistics, Centers Disease Control prevention, Hyattsville, MD MBramlett@cdc.gov Y1 - 2010/07// PY - 2010 DA - July 2010 SP - 248 EP - 267 PB - Taylor & Francis, Philadelphia, PA VL - 13 IS - 3-4 SN - 1092-6755, 1092-6755 KW - adopted children KW - stepchildren KW - National Survey of Children's Health KW - State and Local Area Integrated Telephone Survey KW - Respect KW - Children KW - Adopted Children KW - Sociodemographic Factors KW - Health Care Services KW - article KW - 6143: child & family welfare UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/862780906?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocialservices&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Adoption+Quarterly&rft.atitle=When+Stepparents+Adopt%3A+Demographic%2C+Health+and+Health+Care+Characteristics+of+Adopted+Children%2C+Stepchildren%2C+and+Adopted+Stepchildren&rft.au=Bramlett%2C+Matthew+D&rft.aulast=Bramlett&rft.aufirst=Matthew&rft.date=2010-07-01&rft.volume=13&rft.issue=3-4&rft.spage=248&rft.isbn=&rft.btitle=&rft.title=Adoption+Quarterly&rft.issn=10926755&rft_id=info:doi/10.1080%2F10926755.2010.537954 LA - English DB - Social Services Abstracts N1 - Date revised - 2011-04-18 N1 - Last updated - 2016-09-28 N1 - CODEN - ADQUFW N1 - SubjectsTermNotLitGenreText - Adopted Children; Health Care Services; Sociodemographic Factors; Respect; Children DO - http://dx.doi.org/10.1080/10926755.2010.537954 ER - TY - JOUR T1 - Work Schedules and Health Behavior Outcomes at a Large Manufacturer AN - 754901377; 13554453 AB - There is evidence that work schedules may influence rates of unhealthy behaviors, suggesting that addressing work schedule challenges may improve health. Health Risk Assessment (HRA) survey responses were collected during 2000-2008 in a multinational chemical and coatings manufacturer. Responses of 26,442 were sufficiently complete for analysis. Rates of smoking, lack of exercise, moderate to high alcohol use, obesity (BMI.30), and short sleep duration were compared by work schedule type (day, night, or rotating shift) and daily work hours (8, 10, or 12 h). Prevalence rate ratios (RRs) were calculated, adjusting for age group, sex, marital/living status, job tenure, and occupational group. The reference group was 8-h day shift employees. Overall prevalence rates were: sleep duration of 6 h or less per night 47%, smoking 17.3%, no exercise 22.0%, BMI.30 28.3%, and moderate to heavy alcohol consumption 22.2%. Statistically significant RRs include the following: Short sleep duration: 10 h rotating shift (RR=1.6), 12 h day and 12 h rotating shifts (RR=1.3); Smoking: 12 h day and rotating shifts (RR=1.6), 10 and 12 h night and 8 h rotating shift (RR=1.4); No exercise: 8, 10, and 12 h rotating shifts (RR=1.2 to 1.3), 12 h day schedules (RR=1.3). Obesity (BMI.30): 8 and 10 h night shifts (RR=1.3 and 1.4, respectively). JF - Industrial Health AU - Bushnell, P T AU - Colombi, A AU - Caruso, C C AU - Tak, S W AD - Division of Surveillance, Hazard Evaluations, and Field Studies, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, 4676 Columbia Parkway, MS R17, Cincinnati, Ohio 45226, USA, PLB4@cdc.gov Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 395 EP - 405 VL - 48 IS - 4 SN - 0019-8366, 0019-8366 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Smoking KW - Alcohol KW - Age KW - Behavior KW - obesity KW - marriage KW - working conditions KW - Working conditions KW - Coatings KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754901377?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Industrial+Health&rft.atitle=Work+Schedules+and+Health+Behavior+Outcomes+at+a+Large+Manufacturer&rft.au=Bushnell%2C+P+T%3BColombi%2C+A%3BCaruso%2C+C+C%3BTak%2C+S+W&rft.aulast=Bushnell&rft.aufirst=P&rft.date=2010-07-01&rft.volume=48&rft.issue=4&rft.spage=395&rft.isbn=&rft.btitle=&rft.title=Industrial+Health&rft.issn=00198366&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-09-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Alcohol; Smoking; Age; Behavior; obesity; marriage; Working conditions; working conditions; Coatings ER - TY - JOUR T1 - Contraceptive use among women with a history of bariatric surgery: a systematic review AN - 754870381; 13214212 AB - Weight loss after bariatric surgery often improves fertility but can pose substantial risks to maternal and fetal outcomes. Women who have undergone a bariatric surgical procedure are currently advised to delay conception for up to 2 years. Study Design - We conducted a systematic review of the literature, from database (PubMed) inception through February 2009, to evaluate evidence on the safety and effectiveness of contraceptive use among women with a history of bariatric surgery. Results - From 29 articles, five met review inclusion criteria. One prospective, noncomparative study reported 2 pregnancies among 9 (22%) oral contraceptive (OC) users following biliopancreatic diversion, and one descriptive study reported no pregnancies among an unidentified number of women taking OCs following laparoscopic adjustable gastric banding. Of two pharmacokinetic studies, one found lower plasma levels of norethisterone and levonorgestrel among women having had a jejunoileal bypass, as compared to nonoperated, normal-weight controls. The other study found no difference in plasma levels of D-norgestrel between women having a jejunoileal bypass of either 1:3 or 3:1 ratio between the length of jejunum and ileum left in continuity, but women with a 1:3 ratio had significantly higher plasma levels of D-norgestrel than extremely obese controls not operated upon. Conclusions - Evidence regarding OC effectiveness following a bariatric surgical procedure is quite limited, although no substantial decrease in effectiveness was identified from available studies. Evidence on failure rates for other contraceptive methods and evidence on safety for all contraceptive methods was not identified. JF - Contraception AU - Paulen, Melissa E AU - Zapata, Lauren B AU - Cansino, Catherine AU - Curtis, Kathryn M AU - Jamieson, Denise J AD - Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA, kmc6@cdc.gov Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 86 EP - 94 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 82 IS - 1 SN - 0010-7824, 0010-7824 KW - Risk Abstracts KW - Historical account KW - Fertility KW - obesity KW - surgery KW - Pharmacokinetics KW - contraceptives KW - Pregnancy KW - safety engineering KW - Reviews KW - Females KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754870381?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Contraception&rft.atitle=Contraceptive+use+among+women+with+a+history+of+bariatric+surgery%3A+a+systematic+review&rft.au=Paulen%2C+Melissa+E%3BZapata%2C+Lauren+B%3BCansino%2C+Catherine%3BCurtis%2C+Kathryn+M%3BJamieson%2C+Denise+J&rft.aulast=Paulen&rft.aufirst=Melissa&rft.date=2010-07-01&rft.volume=82&rft.issue=1&rft.spage=86&rft.isbn=&rft.btitle=&rft.title=Contraception&rft.issn=00107824&rft_id=info:doi/10.1016%2Fj.contraception.2010.02.008 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Historical account; Fertility; safety engineering; Reviews; obesity; Females; Pharmacokinetics; surgery; Pregnancy; contraceptives DO - http://dx.doi.org/10.1016/j.contraception.2010.02.008 ER - TY - JOUR T1 - Intrauterine device use among women with ovarian cancer: a systematic review AN - 754869626; 13214206 AB - Fertility-sparing treatment may be an option for women with early stage ovarian cancer and certain tumor types. This systematic review evaluated the evidence on the safety of intrauterine device (IUD) use by women with ovarian cancer. Study Design - We searched the PubMed database for peer-reviewed articles relevant to IUD (copper or levonorgestrel-releasing) use and ovarian cancer published in any language from database inception through August 2009. We sought studies that examined outcomes among women using an IUD at or after ovarian cancer diagnosis. Results - Of the 250 articles identified by our search strategy, none provided evidence (direct or indirect) regarding the safety of IUD use among women with ovarian cancer. Conclusions - No evidence on the safety of IUD use among women with ovarian cancer was identified. While there are some theoretical concerns that IUD use might affect monitoring of disease progression of sex cord-stromal tumors, or increase risk of pelvic infection or vaginal bleeding among women undergoing chemotherapy, we did not find any data to suggest that IUD use would lead to worsening of primary ovarian cancer. JF - Contraception AU - Zapata, Lauren B AU - Whiteman, Maura K AU - Marchbanks, Polly A AU - Curtis, Kathryn M AD - Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA, 30341, USA, lzapata@cdc.gov Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 38 EP - 40 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 82 IS - 1 SN - 0010-7824, 0010-7824 KW - Risk Abstracts KW - ovarian carcinoma KW - tumors KW - Copper KW - chemotherapy KW - safety engineering KW - Reviews KW - infection KW - Females KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754869626?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Contraception&rft.atitle=Intrauterine+device+use+among+women+with+ovarian+cancer%3A+a+systematic+review&rft.au=Zapata%2C+Lauren+B%3BWhiteman%2C+Maura+K%3BMarchbanks%2C+Polly+A%3BCurtis%2C+Kathryn+M&rft.aulast=Zapata&rft.aufirst=Lauren&rft.date=2010-07-01&rft.volume=82&rft.issue=1&rft.spage=38&rft.isbn=&rft.btitle=&rft.title=Contraception&rft.issn=00107824&rft_id=info:doi/10.1016%2Fj.contraception.2010.02.013 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - safety engineering; Reviews; ovarian carcinoma; infection; tumors; Females; Copper; chemotherapy DO - http://dx.doi.org/10.1016/j.contraception.2010.02.013 ER - TY - JOUR T1 - Intrauterine device use among women with uterine fibroids: a systematic review AN - 754869374; 13214208 AB - There are concerns that intrauterine device (IUD) use by women with uterine fibroids might increase their uterine bleeding or risk for device expulsion. The objective of this systematic review was to evaluate evidence concerning the safety and effectiveness of IUD use among women with uterine fibroids. Key questions included whether IUD use is associated with increased risk for uterine bleeding among women with uterine fibroids and whether the presence of uterine fibroids is associated with an increased risk for device expulsion among IUD users. Study Design - We searched the PubMed database for peer-reviewed articles relevant to IUD (copper or levonorgestrel-releasing) use and uterine fibroids published in any language from database inception through June 2009. We used standard abstract forms and a grading system to summarize and assess the quality of the evidence. Results - From 202 articles found in the database search, we identified 11 studies that met our inclusion criteria, all of which examined outcomes among users of the levonorgestrel-releasing IUD (LNG-IUD). Evidence from 10 of 11 noncomparative studies (Level II-3, fair) suggests that LNG-IUD use among women with fibroids does not increase menstrual bleeding, and results from all 11 showed that menstrual blood loss decreased among women who continued to use the LNG-IUD through the end of the study period. Overall, serum levels of hemoglobin, hematocrit and ferritin increased among LNG-IUD users in studies that assessed these outcomes. Several studies reported some occurrences of irregular bleeding. Findings from two cohort studies (Level II-2, fair to poor) showed rates of LNG-IUD expulsion to be higher among women with uterine fibroids (11% in each) than among women without uterine fibroids (0% and 3%); however, in one study the difference was not statistically significant, and in the other significance testing was not conducted. Six prospective noncomparative studies reported expulsion rates of 0-20% among women with uterine fibroids. Conclusions - Most women with uterine fibroids are likely to have less menstrual blood loss and higher serum levels of hemoglobin, hematocrit and ferritin after insertion of an LNG-IUD, despite some occurrences of irregular bleeding. LNG-IUD users with uterine fibroids may have higher rates of expulsion than those without fibroids. JF - Contraception AU - Zapata, Lauren B AU - Whiteman, Maura K AU - Tepper, Naomi K AU - Jamieson, Denise J AU - Marchbanks, Polly A AU - Curtis, Kathryn M AD - Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA, lzapata@cdc.gov Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 41 EP - 55 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 82 IS - 1 SN - 0010-7824, 0010-7824 KW - Risk Abstracts KW - safety engineering KW - Reviews KW - Copper KW - Females KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754869374?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Contraception&rft.atitle=Intrauterine+device+use+among+women+with+uterine+fibroids%3A+a+systematic+review&rft.au=Zapata%2C+Lauren+B%3BWhiteman%2C+Maura+K%3BTepper%2C+Naomi+K%3BJamieson%2C+Denise+J%3BMarchbanks%2C+Polly+A%3BCurtis%2C+Kathryn+M&rft.aulast=Zapata&rft.aufirst=Lauren&rft.date=2010-07-01&rft.volume=82&rft.issue=1&rft.spage=41&rft.isbn=&rft.btitle=&rft.title=Contraception&rft.issn=00107824&rft_id=info:doi/10.1016%2Fj.contraception.2010.02.011 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - safety engineering; Reviews; Females; Copper DO - http://dx.doi.org/10.1016/j.contraception.2010.02.011 ER - TY - JOUR T1 - Safety of contraceptive use among women with peripartum cardiomyopathy: a systematic review AN - 754869267; 13214213 AB - Study Design - Women with peripartum cardiomyopathy (PPCM) have significant health risks during subsequent pregnancies and therefore have a critical need for safe and effective contraception. This systematic review examines evidence regarding the safety of contraceptive use among women with PPCM. Methods - We searched the PubMed database for all primary research articles published through February 2009 that addressed the safety of any contraceptive method among women with PPCM or other cardiomyopathy of any type. Results - Of 110 articles that addressed contraceptive safety among women with cardiac disease, three met our inclusion criteria. In these three studies, which included a total of five women with cardiomyopathy, though not specifically PPCM, cases of hypertension, transient ischemic attack (TIA), thromboembolism or heart failure were found among women with cardiac disease who used hormonal methods of contraception including combined oral contraceptives, progestin-only pills and depot medroxyprogesterone acetate. None of the studies reported any cases of cardiovascular complications or infective endocarditis among women with cardiac disease who used intrauterine devices (IUDs). Conclusions - We found no data concerning the safety of contraceptive use among women with PPCM, though we did find limited evidence of hypertension, TIA, thromboembolism and heart failure among women with cardiac disease who used hormonal methods of contraception. None of the studies reported any cases of cardiovascular complications or infective endocarditis among women with cardiac disease who used IUDs. JF - Contraception AU - Tepper, Naomi K AU - Paulen, Melissa E AU - Marchbanks, Polly A AU - Curtis, Kathryn M AD - Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA, ntepper@cdc.gov Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 95 EP - 101 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 82 IS - 1 SN - 0010-7824, 0010-7824 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Risk assessment KW - thromboembolism KW - contraceptives KW - Pregnancy KW - safety engineering KW - complications KW - Reviews KW - hypertension KW - Females KW - R2 23060:Medical and environmental health KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754869267?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Contraception&rft.atitle=Safety+of+contraceptive+use+among+women+with+peripartum+cardiomyopathy%3A+a+systematic+review&rft.au=Tepper%2C+Naomi+K%3BPaulen%2C+Melissa+E%3BMarchbanks%2C+Polly+A%3BCurtis%2C+Kathryn+M&rft.aulast=Tepper&rft.aufirst=Naomi&rft.date=2010-07-01&rft.volume=82&rft.issue=1&rft.spage=95&rft.isbn=&rft.btitle=&rft.title=Contraception&rft.issn=00107824&rft_id=info:doi/10.1016%2Fj.contraception.2010.02.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Risk assessment; complications; thromboembolism; safety engineering; Reviews; hypertension; Females; Pregnancy; contraceptives DO - http://dx.doi.org/10.1016/j.contraception.2010.02.004 ER - TY - JOUR T1 - Contraceptive use among women with inflammatory bowel disease: A systematic review AN - 754869220; 13214211 AB - There are theoretical concerns that use of hormonal contraceptives by women with inflammatory bowel disease (IBD) might increase disease relapse and risk of other adverse health outcomes, including thrombosis. In addition, there are concerns that IBD-related malabsorption might decrease the effectiveness of orally ingested contraceptives. The objective of this systematic review was to evaluate the evidence on the safety and effectiveness of contraceptive use among women with IBD. Study Design - We searched the PubMed database for peer-reviewed articles relevant to contraceptive use and IBD that were published in any language from inception of the database through February 2009. We used standard abstract forms and grading systems to summarize and assess the quality of the evidence. Results - From 207 articles, we identified 10 studies that met our inclusion criteria. Evidence from five cohort studies (Level II-2, fair to good) suggests no increased risk of IBD relapse with use of oral contraceptives. Evidence from two pharmacokinetic studies (not graded) suggests that women with mild ulcerative colitis and those with an ileostomy following a proctocolectomy with small ileal resections have plasma concentrations of steroid hormones after oral ingestion of higher doses of combined oral contraceptives that are similar to the plasma concentrations among healthy volunteers. No studies were found that examined the risk of thrombosis among women with IBD who used hormonal contraceptives. Conclusions - Limited evidence suggests there is no increased risk of disease relapse among women with IBD who use oral contraceptives, and there seem to be no differences in the absorption of higher-dose combined oral contraceptives between women with mild ulcerative colitis and small ileal resections and healthy women. JF - Contraception AU - Zapata, Lauren B AU - Paulen, Melissa E AU - Cansino, Catherine AU - Marchbanks, Polly A AU - Curtis, Kathryn M AD - Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA, lzapata@cdc.gov Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 72 EP - 85 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 82 IS - 1 SN - 0010-7824, 0010-7824 KW - Risk Abstracts KW - thromboembolism KW - Ingestion KW - Pharmacokinetics KW - contraceptives KW - safety engineering KW - Reviews KW - Absorption KW - steroid hormones KW - Females KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754869220?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Contraception&rft.atitle=Contraceptive+use+among+women+with+inflammatory+bowel+disease%3A+A+systematic+review&rft.au=Zapata%2C+Lauren+B%3BPaulen%2C+Melissa+E%3BCansino%2C+Catherine%3BMarchbanks%2C+Polly+A%3BCurtis%2C+Kathryn+M&rft.aulast=Zapata&rft.aufirst=Lauren&rft.date=2010-07-01&rft.volume=82&rft.issue=1&rft.spage=72&rft.isbn=&rft.btitle=&rft.title=Contraception&rft.issn=00107824&rft_id=info:doi/10.1016%2Fj.contraception.2010.02.012 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - safety engineering; thromboembolism; Reviews; steroid hormones; Absorption; Females; Ingestion; Pharmacokinetics; contraceptives DO - http://dx.doi.org/10.1016/j.contraception.2010.02.012 ER - TY - JOUR T1 - Streptococcus salivarius Meningitis Case Strain Traced to Oral Flora of Anesthesiologist AN - 754868719; 13209875 AB - Two women in labor received intrapartum spinal anesthesia from the same anesthesiologist approximately 1 h apart. Within 15 h, both patients developed Streptococcus salivarius meningitis and one patient died. Blood and cerebrospinal fluid (CSF) samples from both patients and tongue swab specimens from the anesthesiologist yielded isolates of an indistinguishable S. salivarius strain. JF - Journal of Clinical Microbiology AU - Shewmaker, Patricia L AU - Gertz Jr. Jr, Robert E AU - Kim, Clara Y AU - Fijter, Sietske de AU - DiOrio, Mary AU - Moore, Matthew R AU - Beall, Bernard W AD - Respiratory Diseases Branch, Division of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, beb0@cdc.gov Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 2589 EP - 2591 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 48 IS - 7 SN - 0095-1137, 0095-1137 KW - CSA Neurosciences Abstracts; Microbiology Abstracts B: Bacteriology KW - Blood KW - Cerebrospinal fluid KW - Anesthesia KW - Streptococcus salivarius KW - Tongue KW - Meningitis KW - J 02400:Human Diseases KW - N3 11027:Neurology & neuropathology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754868719?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Streptococcus+salivarius+Meningitis+Case+Strain+Traced+to+Oral+Flora+of+Anesthesiologist&rft.au=Shewmaker%2C+Patricia+L%3BGertz+Jr.+Jr%2C+Robert+E%3BKim%2C+Clara+Y%3BFijter%2C+Sietske+de%3BDiOrio%2C+Mary%3BMoore%2C+Matthew+R%3BBeall%2C+Bernard+W&rft.aulast=Shewmaker&rft.aufirst=Patricia&rft.date=2010-07-01&rft.volume=48&rft.issue=7&rft.spage=2589&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.00426-10 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2013-07-15 N1 - SubjectsTermNotLitGenreText - Blood; Cerebrospinal fluid; Anesthesia; Tongue; Meningitis; Streptococcus salivarius DO - http://dx.doi.org/10.1128/JCM.00426-10 ER - TY - JOUR T1 - Alcohol-related injury visits: Do we know the true prevalence in U.S. trauma centres? AN - 754538746; 13254532 AB - Introduction - Alcohol consumption is a significant risk factor for injuries. Further, level I trauma centres are mandated to screen and provide a brief intervention for identified problem drinkers. However, a valid population-based estimate of the magnitude of the problem is unknown. Therefore, the goal of this study is to evaluate the extent to which the present literature provides a valid estimate of the prevalence of alcohol-related visits to U.S. trauma centres. Methods - A Medline search for all articles from 1966 to 2007 that might provide prevalence estimates of alcohol-related visits to U.S. trauma centres yielded 836 articles in English language journals. This review included only papers whose main or secondary goal was to estimate the prevalence of positive blood alcohol concentration (BAC) or acute intoxication. Both a crude aggregate estimate and sample size adjusted estimate were calculated from the included papers and the coverage and comparability of methods were evaluated. Results - Of the 15 studies that met inclusion criteria, incidence estimates of alcohol-related visits ranged from 26.2% to 62.5% and yielded an aggregate, weighted estimate of 32.5%. Target population, capture rate, and threshold for a positive screening result varied considerably across studies. No study provided a comprehensive estimate, i.e., of all trauma patients hospitalised, treated and released, or who died. Conclusions - Although the incidence of alcohol-related visits to U.S. trauma centres appears very high perhaps higher than any other medical setting, the validity of our aggregate estimate is threatened by crucial methodological considerations. The lack of a methodologically valid prevalence estimate hinders efforts to devise appropriate policies for trauma centres and across medical settings. JF - Injury AU - MacLeod, Jana BA AU - Hungerford, Daniel W AD - Dept of Surgery, Emory University School of Medicine, 69 Jesse Hill Jr. Ave., Suite #315, Atlanta, GA 30303, United States, jmacleo@emory.eduJm7072003@yahoo.comdhungerford@cdc.gov Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 847 EP - 851 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 41 IS - 7 SN - 0020-1383, 0020-1383 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Alcohol KW - USA KW - intoxication KW - Injuries KW - Reviews KW - intervention KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754538746?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Injury&rft.atitle=Alcohol-related+injury+visits%3A+Do+we+know+the+true+prevalence+in+U.S.+trauma+centres%3F&rft.au=MacLeod%2C+Jana+BA%3BHungerford%2C+Daniel+W&rft.aulast=MacLeod&rft.aufirst=Jana&rft.date=2010-07-01&rft.volume=41&rft.issue=7&rft.spage=847&rft.isbn=&rft.btitle=&rft.title=Injury&rft.issn=00201383&rft_id=info:doi/10.1016%2Fj.injury.2010.01.098 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Alcohol; intoxication; Injuries; intervention; Reviews; USA DO - http://dx.doi.org/10.1016/j.injury.2010.01.098 ER - TY - JOUR T1 - Declining hip fracture rates in the United States AN - 754143607; 201026867 AB - Unintentional falls are a common occurrence among older adults, affecting 30% of persons aged 65 years & older annually Ill. One of the most serious fall outcomes is hip fracture, an injury that often results in long-term functional impairment, nursing home admission & increased mortality. More than 90% of hip fractures are caused by falls, usually by falling onto the hip. In 2006 there were -- 293,000 hospital admissions for hip fracture. Osteoporosis, a metabolic disease characterised by low bone mineral density (BMD) & bone structure deterioration, greatly increases the chances that a person who falls will sustain a hip fracture. The National Osteoporosis Foundation estimates that more than 10 million people over age 50 in the United States have osteoporosis & another 34 million have low BMD & are at risk for the disease. Extending an earlier & less comprehensive analysis, this studs' used hospital discharge data to analyse the national trends in hip fracture rates from 1990 to 2006 for people aged 65 years & older by both sex & 10-year age groups. Adapted from the source document. JF - Age and Ageing AU - Stevens, Judy A AU - Anne Rudd, Rose AD - National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Mailstop F-62, Atlanta, GA 30341, USA Tel: (+1) 770 488 4649; Fax: (+1) 770 488 1317 Y1 - 2010/07// PY - 2010 DA - July 2010 SP - 500 EP - 503 PB - Oxford University Press, UK VL - 39 IS - 4 SN - 0002-0729, 0002-0729 KW - elderly falls hip fractures osteoporosis trends KW - Elderly people KW - Bone mineral density KW - Falls KW - Fractured hips KW - Osteoporosis KW - Hospitals KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754143607?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Age+and+Ageing&rft.atitle=Declining+hip+fracture+rates+in+the+United+States&rft.au=Stevens%2C+Judy+A%3BAnne+Rudd%2C+Rose&rft.aulast=Stevens&rft.aufirst=Judy&rft.date=2010-07-01&rft.volume=39&rft.issue=4&rft.spage=500&rft.isbn=&rft.btitle=&rft.title=Age+and+Ageing&rft.issn=00020729&rft_id=info:doi/10.1093%2Fageing%2Fafq044 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-10-21 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Fractured hips; Falls; Osteoporosis; Elderly people; Hospitals; Bone mineral density DO - http://dx.doi.org/10.1093/ageing/afq044 ER - TY - JOUR T1 - Determinants of project success among HIV/AIDS nongovernmental organizations (NGOs) in Rakai, Uganda AN - 754141090; 201024440 AB - The aim of the study was to identify the main determinants of grassroots project success among HIV/AIDS NGOs operating in Rakai, Uganda. It was a cross-sectional study using face-to-face interviews in a mixed-methods approach among community members and NGOs involved in providing HIV/AIDS and related health services. The study found that the success of grassroots projects of HIV/AIDS NGOs essentially relies on adequate financial resources, competent human resources, strong organizational leadership, and NGO networking. These data suggest that to increase grassroots project success, HIV and AIDS NGOs in Rakai need to improve not only the budget base and human capacities but as well decision-making processes, organizational vision, mission and strategies, gender allocation in staffing, and beneficiary involvement. [Copyright John Wiley and Sons, Ltd.] JF - The International Journal of Health Planning and Management AU - Bechange, Stevens AD - Uganda Management Institute (UMI), Kampala, Uganda bechanges@ug.cdc.gov Y1 - 2010/07// PY - 2010 DA - July 2010 SP - 215 EP - 230 PB - John Wiley & Sons, Chichester UK VL - 25 IS - 3 SN - 0749-6753, 0749-6753 KW - Cross-sectional studies KW - Uganda KW - Beneficiaries KW - HIV KW - Leadership KW - Nongovernmental organizations KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754141090?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+International+Journal+of+Health+Planning+and+Management&rft.atitle=Determinants+of+project+success+among+HIV%2FAIDS+nongovernmental+organizations+%28NGOs%29+in+Rakai%2C+Uganda&rft.au=Bechange%2C+Stevens&rft.aulast=Bechange&rft.aufirst=Stevens&rft.date=2010-07-01&rft.volume=25&rft.issue=3&rft.spage=215&rft.isbn=&rft.btitle=&rft.title=The+International+Journal+of+Health+Planning+and+Management&rft.issn=07496753&rft_id=info:doi/10.1002%2Fhpm.1025 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-09-10 N1 - Last updated - 2016-09-27 N1 - CODEN - IJHMEO N1 - SubjectsTermNotLitGenreText - HIV; Nongovernmental organizations; Uganda; Beneficiaries; Leadership; Cross-sectional studies DO - http://dx.doi.org/10.1002/hpm.1025 ER - TY - JOUR T1 - HIV Testing and HIV/AIDS Treatment Services in Rural Counties in 10 Southern States: Service Provider Perspectives AN - 754140480; 201023609 AB - Context: Forty percent of AIDS cases are reported in the southern United States, the region with the largest proportion of HIV/AIDS cases from rural areas. Data are limited regarding provider perspectives of the accessibility and availability of HIV testing and treatment services in southern rural counties. Purpose: We surveyed providers in the rural south to better understand: (1) the accessibility and availability, and (2) the facilitators and barriers of HIV testing and treatment services. Methods: All county health departments (N = 326) serving populations of <50,000 persons, within 10 southern states, were mailed surveys. Responding health departments identified up to 3 HIV testing sites and up to 3 HIV treatment sites to which they refer clients. Findings: Overall, 243 of 326 (75%) health departments, 133 of 250 (53%) HIV testing sites, and 73 of 152 (48%) HIV treatment sites responded to the surveys. The number of testing sites per county ranged from 0 to 20; the number of treatment sites ranged from 0 to 4. An average distance of 50 miles for clients to travel for HIV treatment was reported by health department respondents as a barrier. Facilitators of HIV testing were (1) integrating HIV testing into other health services; (2) using rapid HIV testing; and (3) establishing easily accessible HIV testing locations and free testing services. Conclusion: Providers perceive that distance from local health departments to HIV treatment sites presents a barrier to HIV care for their clients. Future studies should ascertain clients' perspectives to ensure appropriate service provisions. Adapted from the source document. JF - The Journal of Rural Health AU - Sutton, Madeline AU - Anthony, Monique-Nicole AU - Vila, Christie AU - McLellan-Lemal, Eleanor AU - Weidle, Paul J AD - Centers for Disease Control and Prevention, Atlanta, Georgia msutton@cdc.gov Y1 - 2010/07// PY - 2010 DA - July 2010 SP - 240 EP - 247 PB - National Rural Health Association, Kansas City MO VL - 26 IS - 3 SN - 0890-765X, 0890-765X KW - Southern States KW - USA KW - Testing KW - Rural communities KW - HIV KW - Accessibility KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754140480?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+Rural+Health&rft.atitle=HIV+Testing+and+HIV%2FAIDS+Treatment+Services+in+Rural+Counties+in+10+Southern+States%3A+Service+Provider+Perspectives&rft.au=Sutton%2C+Madeline%3BAnthony%2C+Monique-Nicole%3BVila%2C+Christie%3BMcLellan-Lemal%2C+Eleanor%3BWeidle%2C+Paul+J&rft.aulast=Sutton&rft.aufirst=Madeline&rft.date=2010-07-01&rft.volume=26&rft.issue=3&rft.spage=240&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+Rural+Health&rft.issn=0890765X&rft_id=info:doi/10.1111%2Fj.1748-0361.2010.00284.x LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-10-21 N1 - Last updated - 2016-09-27 N1 - CODEN - JRHEEX N1 - SubjectsTermNotLitGenreText - HIV; Testing; USA; Rural communities; Accessibility; Southern States DO - http://dx.doi.org/10.1111/j.1748-0361.2010.00284.x ER - TY - JOUR T1 - Estimation of the biodynamic responses distributed at fingers and palm based on the total response of the hand-arm system AN - 753668946; 13211587 AB - The major objective of this study is to develop a modeling method for estimating the biodynamic responses distributed at the fingers and the palm of the hand based on the total driving-point mechanical impedance of the entire hand-arm system. A five degrees-of-freedom (DOF) model with a set of constraints proposed in this study was used in the estimation. Three sets of mechanical impedance data measured at the fingers and palm of the hand were used to examine the validity of the proposed method. The estimated response distributed at the palm was consistent with the measured data even when the real part of the impedance alone was used in the modeling (coefficient of correlation, r super(2) >= 0.902). Better agreements between the estimated and measured responses were obtained (r super(2) >= 0.929) when the magnitude and phase of the total impedance or the magnitude alone were used in the modeling estimation. In each case, the estimated response distributed at the fingers was also reliably correlated with the experimental data (r super(2) >= 0.726) but it was not as consistent with the experimental data as that distributed at the palm. The applications of the proposed method were also demonstrated using five other sets of reported experimental data. This study also demonstrated that the modeling method may also be used to assess the quality of the experimental data in some cases. As a special application of the acceptable data identified in this study, this study also defined a 2-DOF model for the construction of a hand-arm simulator for tool tests. The results of this study and the proposed modeling method are expected to contribute to the revision of ISO 10068 (1998). Relevance to industry - Prolonged exposure to intensive tool vibration could cause hand-arm vibration syndrome (HAVS). An effective approach to reduce the HAVS is to reduce the intensity of the vibration exposure. The proposed modeling method and the results of this study can be used to help develop better tools and anti-vibration devices for reducing the exposure. The modeling study can also be used to help develop the location-specific frequency weightings for assessing the risk of the location-specific disorders induced from the hand-transmitted vibration exposure. JF - International Journal of Industrial Ergonomics AU - Dong, Ren G AU - Rakheja, Subhash AU - McDowell, Thomas W AU - Welcome, Daniel E AU - Wu, John Z AD - Engineering & Control Technology Branch, National Institute for Occupational Safety and Health, 1095 Willowdale Road, MS L-2027, Morgantown, WV 26505, USA, rkd6@cdc.gov Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 425 EP - 436 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 40 IS - 4 SN - 0169-8141, 0169-8141 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Vibration KW - hand-arm vibration syndrome KW - Ergonomics KW - Occupational exposure KW - R2 23080:Industrial and labor KW - H 10000:Ergonomics/Human Factors UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/753668946?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Industrial+Ergonomics&rft.atitle=Estimation+of+the+biodynamic+responses+distributed+at+fingers+and+palm+based+on+the+total+response+of+the+hand-arm+system&rft.au=Dong%2C+Ren+G%3BRakheja%2C+Subhash%3BMcDowell%2C+Thomas+W%3BWelcome%2C+Daniel+E%3BWu%2C+John+Z&rft.aulast=Dong&rft.aufirst=Ren&rft.date=2010-07-01&rft.volume=40&rft.issue=4&rft.spage=425&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Industrial+Ergonomics&rft.issn=01698141&rft_id=info:doi/10.1016%2Fj.ergon.2010.02.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-09-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Vibration; hand-arm vibration syndrome; Occupational exposure; Ergonomics DO - http://dx.doi.org/10.1016/j.ergon.2010.02.001 ER - TY - JOUR T1 - A BOUNDING ESTIMATE OF NEUTRON DOSE BASED ON MEASURED PHOTON DOSE AROUND SINGLE PASS REACTORS AT THE HANFORD SITE AN - 746314607; 13196308 AB - Neutron and photon radiation survey records have been used to evaluate and develop a neutron to photon (NP) ratio to reconstruct neutron doses to workers around Hanford's single pass reactors that operated from 1945 to 1972. A total of 5,773 paired neutron and photon measurements extracted from 57 boxes of survey records were used in the development of the NP ratio. The development of the NP ratio enables the use of the recorded dose from an individual's photon dosimeter badge to be used to estimate the unmonitored neutron dose. The Pearson rank correlation between the neutron and photon measurements was 0.71. The NP ratio best fit a lognormal distribution with a geometric mean (GM) of 0.8, a geometric standard deviation (GSD) of 2.95, and the upper 95 super(th)% of this distribution was 4.75. An estimate of the neutron dose based on this NP ratio is considered bounding due to evidence that up to 70% of the total photon exposure received by workers around the single pass reactors occurs during shutdown maintenance and refueling activities when there is no significant neutron exposure. Thus when this NP ratio is applied to the total measured photon dose from an individual film badge dosimeter, the resulting neutron dose is considered bounded. JF - Health Physics AU - Taulbee, T D AU - Glover, SE AU - Macievic, G V AU - Hunacek, M AU - Smith, C AU - DeBord, G W AU - Morris, D AU - Fix, J AD - National Institute for Occupational Safety and Health (NIOSH), Office of Compensation Analysis and Support (OCAS), Robert A. Taft Laboratories, 4676 Columbia Parkway, Cincinnati, OH 45226, USA, ttaulbee@cdc.gov Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 26 EP - 38 PB - Williams & Wilkins, 351 W. Camden St. Baltimore MD 21201 United States VL - 99 IS - 1 SN - 0017-9078, 0017-9078 KW - Health & Safety Science Abstracts; Pollution Abstracts KW - Nuclear power plants KW - Occupational exposure KW - Maintenance KW - USA, Washington, Hanford Site KW - H 8000:Radiation Safety/Electrical Safety KW - P 8000:RADIATION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/746314607?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+Physics&rft.atitle=A+BOUNDING+ESTIMATE+OF+NEUTRON+DOSE+BASED+ON+MEASURED+PHOTON+DOSE+AROUND+SINGLE+PASS+REACTORS+AT+THE+HANFORD+SITE&rft.au=Taulbee%2C+T+D%3BGlover%2C+SE%3BMacievic%2C+G+V%3BHunacek%2C+M%3BSmith%2C+C%3BDeBord%2C+G+W%3BMorris%2C+D%3BFix%2C+J&rft.aulast=Taulbee&rft.aufirst=T&rft.date=2010-07-01&rft.volume=99&rft.issue=1&rft.spage=26&rft.isbn=&rft.btitle=&rft.title=Health+Physics&rft.issn=00179078&rft_id=info:doi/10.1097%2FHP.0b013e3181d4ee20 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-07-01 N1 - Last updated - 2013-08-12 N1 - SubjectsTermNotLitGenreText - Nuclear power plants; Maintenance; Occupational exposure; USA, Washington, Hanford Site DO - http://dx.doi.org/10.1097/HP.0b013e3181d4ee20 ER - TY - JOUR T1 - Effects of fire fighter protective ensembles on mobility and performance AN - 745713349; 12984665 AB - Many studies have shown that fire fighter turnout gear and equipment may restrict mobility. The restriction of movement is usually due to a decrease in range of motion (ROM). It is important to know how much the decrease in ROM affects performance. The aim of this study was to determine the effects of fire fighter protective ensembles on mobility and performance by measuring static and dynamic range of motion (ROM) and job-related tasks. Eight healthy adults (5 males, 3 females), aged 20-40 years, participated in this study. The study consisted of measuring a battery of motions and fire fighter specific tasks while wearing a standard fire fighter ensemble (SE) or regular light clothing (baseline or BL). Several BL ROM tests were significantly (p < 0.05) different from the SE test, including a decrease in shoulder flexion, cervical rotation and flexion, trunk lateral flexion, and stand and reach. There was a significant decrease in time from SE to baseline performing the one-arm search task and object lift. These overall findings support the need for a comprehensive ergonomic evaluation of protective clothing systems to ascertain human factors issues. The development of a Standard Ergonomics Test Practice for further use in laboratories that conduct personal protective systems evaluations using human test subjects is recommended. JF - Applied Ergonomics AU - Coca, Aitor AU - Williams, WJon AU - Roberge, Raymond J AU - Powell, Jeffrey B AD - National Institute for Occupational Safety and Health, National Personal Protective Technology Laboratory, 626 Cochrans Mill Road, P.O. Box 18070, Pittsburgh, PA 15236, USA, esq6@cdc.gov Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 636 EP - 641 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 41 IS - 4 SN - 0003-6870, 0003-6870 KW - Health & Safety Science Abstracts KW - Fires KW - Protective clothing KW - Mobility KW - Human factors KW - Ergonomics KW - H 6000:Natural Disasters/Civil Defense/Emergency Management UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745713349?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+Ergonomics&rft.atitle=Effects+of+fire+fighter+protective+ensembles+on+mobility+and+performance&rft.au=Coca%2C+Aitor%3BWilliams%2C+WJon%3BRoberge%2C+Raymond+J%3BPowell%2C+Jeffrey+B&rft.aulast=Coca&rft.aufirst=Aitor&rft.date=2010-07-01&rft.volume=41&rft.issue=4&rft.spage=636&rft.isbn=&rft.btitle=&rft.title=Applied+Ergonomics&rft.issn=00036870&rft_id=info:doi/10.1016%2Fj.apergo.2010.01.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-07-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Fires; Protective clothing; Mobility; Human factors; Ergonomics DO - http://dx.doi.org/10.1016/j.apergo.2010.01.001 ER - TY - JOUR T1 - Low-frequency HIV-1 drug resistance mutations can be clinically significant but must be interpreted with caution AN - 745643475; 13150632 AB - With drug-resistant HIV-1 present in at least 10%-20% of new infections in Western countries and in >60% of patients failing antiretroviral therapy (ART), monitoring HIV-1 drug resistance is becoming increasingly important for assessing its impact on therapeutic measures of virus control and for guiding treatment. The sensitivity limitations of conventional bulk genotyping often lead to an underestimation of the total burden of drug resistance in a patient, as resistant variants escape detection when present at low frequency within the viral quasispecies. Using sensitive resistance testing methods, a few investigators have linked low-frequency mutations to poor treatment outcomes, while other studies have shown no correlation. Understanding the technical limitations of sensitive testing methods and the relevance of the amount of a particular resistance mutation in the context of different ART regimens will help to define the clinical benefit of low-frequency resistance testing. Paramount to interpreting the clinical utility of sensitive testing is evaluating resistance mutations selectively, at biologically significant frequencies, and using methods that have been broadly validated on clinical specimens. JF - Journal of Antimicrobial Chemotherapy AU - Johnson, Jeffrey A AU - Geretti, Anna Maria AD - 2 Department of Virology, Royal Free Hampstead NHS Trust and UCL Medical School, London, UK, jjohnson1@cdc.gov Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 1322 EP - 1326 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK VL - 65 IS - 7 SN - 0305-7453, 0305-7453 KW - Toxicology Abstracts; Virology & AIDS Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Drug resistance KW - Genotyping KW - Human immunodeficiency virus 1 KW - antiretroviral therapy KW - Infection KW - Mutation KW - A 01340:Antibiotics & Antimicrobials KW - V 22360:AIDS and HIV KW - X 24310:Pharmaceuticals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745643475?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Antimicrobial+Chemotherapy&rft.atitle=Low-frequency+HIV-1+drug+resistance+mutations+can+be+clinically+significant+but+must+be+interpreted+with+caution&rft.au=Johnson%2C+Jeffrey+A%3BGeretti%2C+Anna+Maria&rft.aulast=Johnson&rft.aufirst=Jeffrey&rft.date=2010-07-01&rft.volume=65&rft.issue=7&rft.spage=1322&rft.isbn=&rft.btitle=&rft.title=Journal+of+Antimicrobial+Chemotherapy&rft.issn=03057453&rft_id=info:doi/10.1093%2Fjac%2Fdkq139 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-07-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Genotyping; Drug resistance; antiretroviral therapy; Infection; Mutation; Human immunodeficiency virus 1 DO - http://dx.doi.org/10.1093/jac/dkq139 ER - TY - JOUR T1 - Dopaminergic neurotoxicity following pulmonary exposure to manganese-containing welding fumes. AN - 733352044; 20224926 AB - The potential for development of Parkinson's disease (PD)-like neurological dysfunction following occupational exposure to aerosolized welding fumes (WF) is an area of emerging concern. Welding consumables contain a complex mixture of metals, including iron (Fe) and manganese (Mn), which are known to be neurotoxic. To determine whether WF exposure poses a neurological risk particularly to the dopaminergic system, we treated Sprague-Dawley rats with WF particulates generated from two different welding processes, gas metal arc-mild steel (GMA-MS; low Mn, less water-soluble) and manual metal arc-hard surfacing (MMA-HS; high Mn, more water-soluble) welding. Following repeated intratracheal instillations (0.5 mg/rat, 1/week x 7 weeks) of GMA-MS or MMA-HS, elemental analysis and various molecular indices of neurotoxicity were measured at 1, 4, 35 or 105 days after last exposure. MMA-HS exposure, in particular, led to increased deposition of Mn in striatum and midbrain. Both fumes also caused loss of tyrosine hydroxylase (TH) protein in the striatum (~20%) and midbrain (~30%) by 1 day post-exposure. While the loss of TH following GMA-MS was transient, a sustained loss (34%) was observed in the midbrain 105 days after cessation of MMA-HS exposure. In addition, both fumes caused persistent down-regulation of dopamine D2 receptor (Drd2; 30-40%) and vesicular monoamine transporter 2 (Vmat2; 30-55%) mRNAs in the midbrain. WF exposure also modulated factors associated with synaptic transmission, oxidative stress, neuroinflammation and gliosis. Collectively, our findings demonstrate that repeated exposure to Mn-containing WF can cause persistent molecular alterations in dopaminergic targets. Whether such perturbations will lead to PD-like neuropathological manifestations remains to be elucidated. JF - Archives of toxicology AU - Sriram, Krishnan AU - Lin, Gary X AU - Jefferson, Amy M AU - Roberts, Jenny R AU - Chapman, Rebecca S AU - Chen, Bean T AU - Soukup, Joleen M AU - Ghio, Andrew J AU - Antonini, James M AD - Health Effects Laboratory Division, National Institute For Occupational Safety and Health, Morgantown, WV 26505, USA. kos4@cdc.gov Y1 - 2010/07// PY - 2010 DA - July 2010 SP - 521 EP - 540 VL - 84 IS - 7 KW - Gases KW - 0 KW - Metals KW - Steel KW - 12597-69-2 KW - Manganese KW - 42Z2K6ZL8P KW - Iron KW - E1UOL152H7 KW - Dopamine KW - VTD58H1Z2X KW - Index Medicus KW - Occupational Exposure KW - Animals KW - Neurotoxicity Syndromes KW - Gases -- metabolism KW - Lung -- metabolism KW - Iron -- metabolism KW - Rats KW - Rats, Sprague-Dawley KW - Steel -- toxicity KW - Down-Regulation KW - Parkinson Disease KW - Metals -- metabolism KW - Male KW - Metals -- toxicity KW - Manganese -- metabolism KW - Welding UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733352044?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Archives+of+toxicology&rft.atitle=Dopaminergic+neurotoxicity+following+pulmonary+exposure+to+manganese-containing+welding+fumes.&rft.au=Sriram%2C+Krishnan%3BLin%2C+Gary+X%3BJefferson%2C+Amy+M%3BRoberts%2C+Jenny+R%3BChapman%2C+Rebecca+S%3BChen%2C+Bean+T%3BSoukup%2C+Joleen+M%3BGhio%2C+Andrew+J%3BAntonini%2C+James+M&rft.aulast=Sriram&rft.aufirst=Krishnan&rft.date=2010-07-01&rft.volume=84&rft.issue=7&rft.spage=521&rft.isbn=&rft.btitle=&rft.title=Archives+of+toxicology&rft.issn=1432-0738&rft_id=info:doi/10.1007%2Fs00204-010-0525-9 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-09-10 N1 - Date created - 2010-06-17 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1007/s00204-010-0525-9 ER - TY - JOUR T1 - Protecting Workers in Large-Scale Emergency Responses:NIOSH Experience in the Deepwater Horizon Response AN - 1020837063; 15498084 AB - On April 20, 2010, the Deepwater Horizon (DWH) semisubmersible Mobile Offshore Drilling Unit, located 45 miles southeast off the Louisiana coast, suffered a massive explosion and subsequent fire that ultimately led to the sinking of the Unit. Eleven workers lost their lives as a result of the explosion and fire, and seventeen other workers were injured. Oil from a subsea blowout began flowing into the Gulf of Mexico soon after the explosion, and continued to flow until the well was finally capped on July 15, 2010. JF - Journal of Occupational and Environmental Medicine AU - Kitt, M M AU - Decker, JA AU - Delaney, L AU - Funk, R AU - Halpin, J AU - Tepper, A AU - Spahr, J AU - Howard, J AD - National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, 1600 Clifton Rd, Mail Stop E-20, Atlanta, GA 30333, USA, mkitt@cdc.gov Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 711 EP - 715 VL - 53 IS - 7 SN - 1076-2752, 1076-2752 KW - Health & Safety Science Abstracts KW - Coastal zone KW - Emergency preparedness KW - Explosions KW - Fires KW - Oil KW - ASW, USA, Louisiana KW - ASW, Mexico Gulf KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1020837063?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Protecting+Workers+in+Large-Scale+Emergency+Responses%3ANIOSH+Experience+in+the+Deepwater+Horizon+Response&rft.au=Kitt%2C+M+M%3BDecker%2C+JA%3BDelaney%2C+L%3BFunk%2C+R%3BHalpin%2C+J%3BTepper%2C+A%3BSpahr%2C+J%3BHoward%2C+J&rft.aulast=Kitt&rft.aufirst=M&rft.date=2010-07-01&rft.volume=53&rft.issue=7&rft.spage=711&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e31822543b6 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-06-01 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - Oil; Fires; Coastal zone; Emergency preparedness; Explosions; ASW, Mexico Gulf; ASW, USA, Louisiana DO - http://dx.doi.org/10.1097/JOM.0b013e31822543b6 ER - TY - CPAPER T1 - Lessons learned from the field, how to protect yourself from occupational exposure to engineered nanomaterials T2 - 2010 Symposium on Environment, Health & Safety AN - 839696954; 5927164 JF - 2010 Symposium on Environment, Health & Safety AU - Hodson, L AU - Geraci, C AU - Methner, M AU - Crawford, C Y1 - 2010/06/21/ PY - 2010 DA - 2010 Jun 21 KW - {Q1} KW - Occupational exposure KW - Nanotechnology KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839696954?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2010+Symposium+on+Environment%2C+Health+%26+Safety&rft.atitle=Lessons+learned+from+the+field%2C+how+to+protect+yourself+from+occupational+exposure+to+engineered+nanomaterials&rft.au=Hodson%2C+L%3BGeraci%2C+C%3BMethner%2C+M%3BCrawford%2C+C&rft.aulast=Hodson&rft.aufirst=L&rft.date=2010-06-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2010+Symposium+on+Environment%2C+Health+%26+Safety&rft.issn=&rft_id=info:doi/ L2 - http://www.techconnectworld.com/Nanotech2010/symposia/Environment_Soci LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-11 N1 - Last updated - 2011-01-14 ER - TY - JOUR T1 - AIDS-defining opportunistic illnesses in US patients, 1994-2007: a cohort study AN - 746308938; 13195977 AB - Objectives: To assess the incidence and spectrum of AIDS-defining opportunistic illnesses in the highly active antiretroviral therapy (cART) era. Design: A prospective cohort study of 8070 participants in the HIV Outpatient Study at 12 U.S. HIV clinics. Methods: We calculated incidence rates per 1000 person-years of observation for the first opportunistic infection, first opportunistic malignancy, and first occurrence of each individual opportunistic illness during 1994-2007. Using stratified Poisson regression models, and adjusting for sex, race, and HIV risk category, we modeled annual percentage changes in opportunistic illness incidence rates by calendar period. Results: Eight thousand and seventy patients (baseline median age 38 years; median CD4 cell count 298 cells/kl) experienced 2027 incident opportunistic illnesses during a median of 2.9 years of observation. During 1994-1997, 1998-2002, and 2003-2007, respectively, rates of opportunistic infections (per 1000 person-years) were 89.0, 25.2 and 13.3 and rates of opportunistic malignancies were 23.4, 5.8 and 3.0 (P for trend <0.001 for both). Opportunistic illness rate decreases were similar for the subset of patients receiving cART. During 2003-2007, there were no significant changes in annual rates of opportunistic infections or opportunistic malignancies; the leading opportunistic illnesses (rate per 1000 person-years) were esophageal candidiasis (5.2), Pneumocystis pneumonia (3.9), cervical cancer (3.5), Mycobacterium avium complex infection (2.5), and cytomegalovirus disease (1.8); 36% opportunistic illness events occurred at CD4 cell counts at least 200cells/kl. Conclusions: Opportunistic illness rates declined precipitously after introduction of cART and stabilized at low levels during 2003-2007. In this contemporary cART era, a third of opportunistic illnesses were diagnosed at CD4 cell counts at least 200 cells/kl. JF - AIDS AU - Buchacz, K AU - Baker, R K AU - Palella, FJ Jr AU - Chmiel, J S AU - Lichtenstein, KA AU - Novak, R M AU - Wood, K C AU - Brooks, J T AD - Centers for Disease Control and Prevention, 1600 Clifton Road NE, Mailstop E-45, Atlanta, GA 30333, USA, acu7@cdc.gov Y1 - 2010/06/19/ PY - 2010 DA - 2010 Jun 19 SP - 1549 EP - 1559 VL - 24 IS - 10 SN - 0269-9370, 0269-9370 KW - Microbiology Abstracts B: Bacteriology; Risk Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - Esophagus KW - Acquired immune deficiency syndrome KW - Age KW - Mycobacterium avium KW - Candidiasis KW - Cervical cancer KW - Pneumocystis KW - Cytomegalovirus KW - Cancer KW - Opportunist infection KW - USA KW - Malignancy KW - CD4 antigen KW - Human immunodeficiency virus KW - highly active antiretroviral therapy KW - antiretroviral agents KW - infection KW - Regression analysis KW - Pneumonia KW - Races KW - Sex KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/746308938?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS&rft.atitle=AIDS-defining+opportunistic+illnesses+in+US+patients%2C+1994-2007%3A+a+cohort+study&rft.au=Buchacz%2C+K%3BBaker%2C+R+K%3BPalella%2C+FJ+Jr%3BChmiel%2C+J+S%3BLichtenstein%2C+KA%3BNovak%2C+R+M%3BWood%2C+K+C%3BBrooks%2C+J+T&rft.aulast=Buchacz&rft.aufirst=K&rft.date=2010-06-19&rft.volume=24&rft.issue=10&rft.spage=1549&rft.isbn=&rft.btitle=&rft.title=AIDS&rft.issn=02699370&rft_id=info:doi/10.1097%2FQAD.0b013e32833a3967 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-07-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Esophagus; Age; CD4 antigen; Malignancy; Candidiasis; highly active antiretroviral therapy; Cervical cancer; Regression analysis; Races; Pneumonia; Sex; Opportunist infection; Acquired immune deficiency syndrome; Human immunodeficiency virus; antiretroviral agents; infection; Cancer; Mycobacterium avium; Pneumocystis; Cytomegalovirus; USA DO - http://dx.doi.org/10.1097/QAD.0b013e32833a3967 ER - TY - CPAPER T1 - Cost Analysis of the Accreditation Process, a Case Scenario of CDC/KEMRI HIV Research Lab- Kisumu T2 - 29th World Congress of Biomedical Laboratory Science AN - 754280557; 5847402 JF - 29th World Congress of Biomedical Laboratory Science AU - Zeh, Clement AU - Omondi, Kevin AU - Songwe, Kilian Y1 - 2010/06/06/ PY - 2010 DA - 2010 Jun 06 KW - Kenya, Nyanza, Kisumu KW - Human immunodeficiency virus KW - Cost analysis KW - Accreditation KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754280557?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=29th+World+Congress+of+Biomedical+Laboratory+Science&rft.atitle=Cost+Analysis+of+the+Accreditation+Process%2C+a+Case+Scenario+of+CDC%2FKEMRI+HIV+Research+Lab-+Kisumu&rft.au=Zeh%2C+Clement%3BOmondi%2C+Kevin%3BSongwe%2C+Kilian&rft.aulast=Zeh&rft.aufirst=Clement&rft.date=2010-06-06&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=29th+World+Congress+of+Biomedical+Laboratory+Science&rft.issn=&rft_id=info:doi/ L2 - http://www.akmlso-ifbls2010.org/OnlyProgram.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - JOUR T1 - Path forward: Emerging issues and challenges AN - 754880699; 13398064 AB - The NIOSH Construction Program worked with industry stakeholders to develop a National Occupational Safety and Health Construction Agenda to target future research and activities. The Program and its partners are also cognizant that new developments can emerge over time and that research can play an important role in helping to understand and address these emerging issues. Examples of emerging issues relevant to construction safety and health are described. These include: (a) climate change and energy considerations; (b) green construction developments and opportunities; (c) new materials; (d) changes in industry structure and practice; (e) workforce developments and disparities; (f) injury underreporting and cost and risk shifting; and (g) increased interest in addressing root causes. Responding to emerging issues while maintaining a focus on fundamental longstanding issues represents an ongoing challenge for researchers and industry organizations. Additional research to understand the diffusion and adoption of research by the industry is also needed. Research accomplished to date provides a strong foundation for addressing future industry needs and trends. JF - Journal of Safety Research AU - Gillen, Matt AU - Gittleman, Janie L AD - The National Institute for Occupational Safety and Health Office of Construction Safety and Health, 395 E Street, SW, Washington, DC 20201, mgillen@cdc.gov Y1 - 2010/06// PY - 2010 DA - June 2010 SP - 301 EP - 306 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK VL - 41 IS - 3 SN - 0022-4375, 0022-4375 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Emerging Issues KW - Construction Industry changes KW - Research challenges KW - NORA National Construction Agenda KW - Green construction KW - Injuries KW - Occupational safety KW - Climate change KW - Diffusion KW - stakeholders KW - Construction industry KW - R2 23080:Industrial and labor KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754880699?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Safety+Research&rft.atitle=Path+forward%3A+Emerging+issues+and+challenges&rft.au=Gillen%2C+Matt%3BGittleman%2C+Janie+L&rft.aulast=Gillen&rft.aufirst=Matt&rft.date=2010-06-01&rft.volume=41&rft.issue=3&rft.spage=301&rft.isbn=&rft.btitle=&rft.title=Journal+of+Safety+Research&rft.issn=00224375&rft_id=info:doi/10.1016%2Fj.jsr.2010.04.005 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-09-01 N1 - Last updated - 2016-07-07 N1 - SubjectsTermNotLitGenreText - Injuries; Climate change; Occupational safety; Diffusion; stakeholders; Construction industry DO - http://dx.doi.org/10.1016/j.jsr.2010.04.005 ER - TY - JOUR T1 - The NIOSH Construction Program: Research to practice, impact, and developing a National Construction Agenda AN - 754880179; 13398063 AB - The U.S. National Institute for Occupational Safety and Health (NIOSH) conducts research to improve and protect the health and safety of workers. This paper describes the experience of the NIOSH Construction Program with two recent program planning initiatives intended to improve the program: (a) an independent external review of work over the past decade and (b) the development of strategic goals organized into a QUOTATION_MARKNational Construction AgendaQUOTATION_MARK to guide a decade of future work. These goals, developed with input from construction industry stakeholders and researchers, are a part of the NIOSH National Occupational Research Agenda (NORA) initiative. The NORA goals are intended to provide an ambitious set of goals for all construction stakeholders to work together on. Both efforts relate to insuring the relevance and impact of research, reflecting an emerging policy perspective that research programs should be judged not just by the quality and quantity of science produced, but by the industry impact and tangible benefit resulting from the research. This paper describes how views on research planning have evolved to incorporate lessons learned about how research leads to improved safety and health for workers. It also describes the process used to develop the goals and the resulting strategic and intermediate goals that comprise the National Construction Agenda. JF - Journal of Safety Research AU - Gillen, Matt AD - The National Institute for Occupational Safety and Health Office of Construction Safety and Health, 395 E Street, SW, Washington, DC 20201, mgillen@cdc.gov Y1 - 2010/06// PY - 2010 DA - Jun 2010 SP - 289 EP - 299 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK VL - 41 IS - 3 SN - 0022-4375, 0022-4375 KW - Health & Safety Science Abstracts KW - USA KW - Reviews KW - Occupational safety KW - stakeholders KW - Construction industry KW - Research programs KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754880179?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Safety+Research&rft.atitle=The+NIOSH+Construction+Program%3A+Research+to+practice%2C+impact%2C+and+developing+a+National+Construction+Agenda&rft.au=Gillen%2C+Matt&rft.aulast=Gillen&rft.aufirst=Matt&rft.date=2010-06-01&rft.volume=41&rft.issue=3&rft.spage=289&rft.isbn=&rft.btitle=&rft.title=Journal+of+Safety+Research&rft.issn=00224375&rft_id=info:doi/10.1016%2Fj.jsr.2010.04.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-09-01 N1 - Last updated - 2014-07-24 N1 - SubjectsTermNotLitGenreText - Reviews; Occupational safety; stakeholders; Research programs; Construction industry; USA DO - http://dx.doi.org/10.1016/j.jsr.2010.04.002 ER - TY - JOUR T1 - Effectiveness of a worker-worn electric-field sensor to detect power-line proximity and electrical-contact AN - 754879905; 13398057 AB - Problem - Construction workers suffer the most electrocutions among all industries. Currently, there are no electrical contact warning devices on the market to protect workers. This paper proposes a worker-worn electric-field sensor. As the worker is in proximity to, or in contact with, a live power-circuit, the sensor sets off an audible/visual warning alarm. The sensor also has the potential to wirelessly trip a wireless-capable circuit breaker, and to trigger a wireless transmitter to notify emergency response of an electrical contact. Methods - An experiment was conducted to measure electric-field variation on simulated human-wrists (10 defrosted hog-legs) in various proximities and in electrical-contact to a simulated power-circuit. The purpose of these tests was to determine the feasibility of developing a worker-worn electric-field detection sensor for use in protecting workers from contact with energized electrical conductors. Results - This study observed a significant electric-field-magnitude increase as a hog-leg approaches the live-circuit, and the distinct electric-field-magnitude jump as the leg contacts with the live-circuit. The observation indicates that this sensor can be an effective device to warn the workers of electrical hazards. Additionally, the sensor has the potential to wirelessly trip a wireless-capable circuit-breaker and trigger a wireless transmitter (such as a cell phone) to notify an emergency response. The prompt notification prevents the worker from further injury caused by postponed medical-care. Impact on Industry - Widespread use of this sensor could lower electrocution and electrically related injury rates in the construction industry. JF - Journal of Safety Research AU - Zeng, Shengke AU - Powers, John R AU - Newbraugh, Bradley H AD - Division of Safety Research, National Institute for Occupational Safety and Health, szeng@cdc.gov Y1 - 2010/06// PY - 2010 DA - Jun 2010 SP - 229 EP - 239 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK VL - 41 IS - 3 SN - 0022-4375, 0022-4375 KW - Health & Safety Science Abstracts KW - Feasibility studies KW - cellular telephones KW - Sensors KW - Injuries KW - Emergency preparedness KW - Construction industry KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754879905?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Safety+Research&rft.atitle=Effectiveness+of+a+worker-worn+electric-field+sensor+to+detect+power-line+proximity+and+electrical-contact&rft.au=Zeng%2C+Shengke%3BPowers%2C+John+R%3BNewbraugh%2C+Bradley+H&rft.aulast=Zeng&rft.aufirst=Shengke&rft.date=2010-06-01&rft.volume=41&rft.issue=3&rft.spage=229&rft.isbn=&rft.btitle=&rft.title=Journal+of+Safety+Research&rft.issn=00224375&rft_id=info:doi/10.1016%2Fj.jsr.2010.02.011 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-09-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Feasibility studies; cellular telephones; Injuries; Sensors; Emergency preparedness; Construction industry DO - http://dx.doi.org/10.1016/j.jsr.2010.02.011 ER - TY - JOUR T1 - A Large Q Fever Outbreak in an Urban School in Central Israel AN - 754541395; 13267152 AB - Background. On 28 June 2005, numerous cases of febrile illness were reported among 322 students and employees of a boarding high school located in an urban area in central Israel. Subsequent investigation identified a large outbreak of Q fever which started 2 weeks earlier. We describe the investigation of this outbreak and its possible implications. Methods. We conducted a case-control study to Identify risk factors for Q fever disease. Environmental sampling was conducted to Identify the source and the mode of transmission of Coxlella burnetll, the infectious agent. Results. Of 303 individuals, 187 (62%) reported being ill between 15 June and 13 July 2005. Serological evidence for C. burnetll infection was evident In 144 (88%) of the 164 tested individuals. Being a student, dining regularly at the school dining room, and boarding at school during a June religious holiday and the preceding weekend were all significant risk factors for contracting Q fever. C. burnetll DNA was detected using polymerase chain reaction on samples from the school dining room's air conditioning system, supporting contribution of the air conditioning system to the aerosol transmission of the infectious agent. Conclusions. We report a large outbreak of Q fever in an urban school, possibly transmitted through an air conditioning system. A high level of suspicion for C. burnetil infection should be maintained when investigating point source outbreaks of influenza-like disease, especially outside the influenza season. JF - Clinical Infectious Diseases AU - Amitai, Z AU - Bromberg, M AU - Bernstein, M AU - Raven, D AU - Keysary, A AU - David, D AU - Pitllk, S AU - Swerdlow, D AU - Massung, R AU - Rzotklewicz, S AU - Halutz, O AU - Shohat, T AD - The Israel Center for Disease Control, Gertner Institute, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel, michal.bromberg@icdc-health.gov.il Y1 - 2010/06/01/ PY - 2010 DA - 2010 Jun 01 SP - 1433 EP - 1438 VL - 50 IS - 11 SN - 1058-4838, 1058-4838 KW - Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts KW - Influenza KW - Aerosols KW - Air conditioning KW - Risk factors KW - Polymerase chain reaction KW - Sampling KW - Infection KW - Q fever KW - Disease transmission KW - J 02400:Human Diseases KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754541395?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+Infectious+Diseases&rft.atitle=A+Large+Q+Fever+Outbreak+in+an+Urban+School+in+Central+Israel&rft.au=Amitai%2C+Z%3BBromberg%2C+M%3BBernstein%2C+M%3BRaven%2C+D%3BKeysary%2C+A%3BDavid%2C+D%3BPitllk%2C+S%3BSwerdlow%2C+D%3BMassung%2C+R%3BRzotklewicz%2C+S%3BHalutz%2C+O%3BShohat%2C+T&rft.aulast=Amitai&rft.aufirst=Z&rft.date=2010-06-01&rft.volume=50&rft.issue=11&rft.spage=1433&rft.isbn=&rft.btitle=&rft.title=Clinical+Infectious+Diseases&rft.issn=10584838&rft_id=info:doi/10.1086%2F652442 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Influenza; Aerosols; Air conditioning; Risk factors; Polymerase chain reaction; Sampling; Infection; Q fever; Disease transmission DO - http://dx.doi.org/10.1086/652442 ER - TY - JOUR T1 - Translating Evidence into Policy: Lessons Learned from the Case of Lowering the Legal Blood Alcohol Limit for Drivers AN - 754531385; 13210583 AB - This case study examines the translation of evidence on the effectiveness of laws to reduce the blood alcohol concentration (BAC) of drivers into policy. It was reconstructed through discussions among individuals involved in the processes as well as a review of documentation and feedback on oral presentations. The Centers for Disease Control and Prevention collaborated extensively with federal and non-federal partners and stakeholders in conducting a rigorous systematic review, using the processes of the Guide to Community Preventive Services to evaluate the body of empirical evidence on 0.08%C laws. The timely dissemination of the findings and related policy recommendations - made by the independent Task Force on Community Preventive Services - to Congress very likely contributed to the inclusion of strong incentives to States to adopt 0.08C laws by October 2003. Subsequent dissemination to partners and stakeholders informed decision-making about support for state legislative and policy action. This case study suggests the value of: clearly outlining the relationships between health problems, interventions and outcomes; systematically assessing and synthesizing the evidence; using a credible group and rigorous process to assess the evidence; having an impartial body make specific policy recommendations on the basis of the evidence; being ready to capitalize in briefly opening policy windows; engaging key partners and stakeholders throughout the production and dissemination of the evidence and recommendations; undertaking personalized, targeted and compelling dissemination of the evidence and recommendations; involving multiple stakeholders in encouraging uptake and adherence of policy recommendations; and addressing sustainability. These lessons learned may help others working to translate evidence into policy. JF - Annals of Epidemiology AU - Mercer, Shawna L AU - Sleet, David A AU - Elder, Randy W AU - Cole, Krista Hopkins AU - Shults, Ruth A AU - Nichols, James L AD - Community Guide Branch, Epidemiology and Analysis Program Office (Proposed), Office of Surveillance, Epidemiology, and Laboratory Services (Proposed), Centers for Disease Control and Prevention (CDC), Atlanta, GA, SMercer@cdc.gov Y1 - 2010/06// PY - 2010 DA - Jun 2010 SP - 412 EP - 420 PB - Elsevier Science, Box 882 New York NY 10159 USA VL - 20 IS - 6 SN - 1047-2797, 1047-2797 KW - Health & Safety Science Abstracts; Sustainability Science Abstracts KW - Accidents, Traffic KW - Alcoholic Intoxication KW - Evidence-Based Practice KW - Information Dissemination KW - Public Policy KW - Review, Systematic KW - Translational Research KW - Alcohol KW - Congress KW - incentives KW - disease control KW - case studies KW - health problems KW - Reviews KW - intervention KW - prevention KW - sustainability KW - stakeholders KW - Legislation KW - M3 1010:Issues in Sustainable Development KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754531385?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annals+of+Epidemiology&rft.atitle=Translating+Evidence+into+Policy%3A+Lessons+Learned+from+the+Case+of+Lowering+the+Legal+Blood+Alcohol+Limit+for+Drivers&rft.au=Mercer%2C+Shawna+L%3BSleet%2C+David+A%3BElder%2C+Randy+W%3BCole%2C+Krista+Hopkins%3BShults%2C+Ruth+A%3BNichols%2C+James+L&rft.aulast=Mercer&rft.aufirst=Shawna&rft.date=2010-06-01&rft.volume=20&rft.issue=6&rft.spage=412&rft.isbn=&rft.btitle=&rft.title=Annals+of+Epidemiology&rft.issn=10472797&rft_id=info:doi/10.1016%2Fj.annepidem.2010.03.005 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - health problems; case studies; Alcohol; intervention; Congress; Reviews; prevention; sustainability; incentives; disease control; stakeholders; Legislation DO - http://dx.doi.org/10.1016/j.annepidem.2010.03.005 ER - TY - JOUR T1 - Newspaper Reports: A Source of Surveillance for Burns among Women in Pakistan AN - 754139711; 201022644 AB - Background: Our study attempts to describe the demographics, characteristics of victims and perpetrators, and circumstances leading to burn events among females in Pakistan. Methods: Human Rights Commission of Pakistan (HRCP) systematically collected data on burns among women using newspaper reports from January 2004 till December 2005. We analyzed the aggregated data and estimated burn rates. Results: A total of 222 burn events were reported from 2004 to 2005; complete data were not available for all variables. Adults (18 years) constituted 74% (91/123) of cases with 95% (121/127) being married. Most burns were caused by bursting of stoves (34%; 64/189) or victims set-on fire (33%; n = 63/189). Burns using acids accounted for 13% (25/189). Husbands (52%; 51/98) and in-laws (23%; 23/98) were the perpetrators in known burn events. Burns were classified as accidental in half of cases (51%; 97/189) and related to domestic issues in a quarter (25%; 47/189). There were 49% of (92/189) burns that were reported as intentional. The mean annual rate of burns among women (1564 years of age) was found to be 33 per 100 000. Conclusion: Newspaper reports are good source of surveillance when information is otherwise limited. Majority of burns (51%) were classified as accidental while 49% were reported as intentional, though there is a limitation in the accuracy of reported accidental events. There is a dire need for systematic data collection and devising preventive strategies for this important public health problem that remains largely neglected in Pakistan. Adapted from the source document. JF - Journal of Public Health AU - Nasrullah, Muazzam AU - Muazzam, Sana AD - Centers for Disease Control and Prevention (CDC), National Institute for Occupational Safety and Health (NIOSH), Morgantown, WV E-mail: snasrullah@cdc.gov, mnasrullah@hsc.wvu.edu Y1 - 2010/06// PY - 2010 DA - June 2010 SP - 245 EP - 249 PB - Oxford University Press VL - 32 IS - 2 SN - 1741-3842, 1741-3842 KW - burns, cultural practices, dowry, gender, Pakistan, stove, violence KW - Newspapers KW - Burns KW - Pakistan KW - Women KW - Perpetrators KW - Surveillance KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754139711?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Public+Health&rft.atitle=Newspaper+Reports%3A+A+Source+of+Surveillance+for+Burns+among+Women+in+Pakistan&rft.au=Nasrullah%2C+Muazzam%3BMuazzam%2C+Sana&rft.aulast=Nasrullah&rft.aufirst=Muazzam&rft.date=2010-06-01&rft.volume=32&rft.issue=2&rft.spage=245&rft.isbn=&rft.btitle=&rft.title=Journal+of+Public+Health&rft.issn=17413842&rft_id=info:doi/10.1093%2Fpubmed%2Ffdp102 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-08-09 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Burns; Pakistan; Women; Newspapers; Surveillance; Perpetrators DO - http://dx.doi.org/10.1093/pubmed/fdp102 ER - TY - JOUR T1 - Medical toxicology and public health: update on research and activities at the Centers for Disease Control and Prevention and the Agency for Toxic Substances and Disease Registry: introduction to activities at the radiation studies branch. AN - 748936173; 20358413 JF - Journal of medical toxicology : official journal of the American College of Medical Toxicology AU - Kazzi, Ziad N AU - Nemhauser, Jeffrey B AU - Ansari, Armin AU - McCurley, Carol AU - Whitcomb, Robert AU - Miller, Charles AD - Radiation Studies Branch, Division of Environmental Hazards and Health Effects, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA. zkazzi@cdc.gov Y1 - 2010/06// PY - 2010 DA - June 2010 SP - 230 EP - 233 VL - 6 IS - 2 SN - 1556-9039, 1556-9039 KW - Hazardous Substances KW - 0 KW - Index Medicus KW - United States KW - Registries KW - Radiation KW - Civil Defense KW - Humans KW - Government Agencies KW - Guidelines as Topic KW - Research KW - Health Education KW - Centers for Disease Control and Prevention (U.S.) KW - Toxicology -- trends KW - Toxicology -- education UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/748936173?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+medical+toxicology+%3A+official+journal+of+the+American+College+of+Medical+Toxicology&rft.atitle=Medical+toxicology+and+public+health%3A+update+on+research+and+activities+at+the+Centers+for+Disease+Control+and+Prevention+and+the+Agency+for+Toxic+Substances+and+Disease+Registry%3A+introduction+to+activities+at+the+radiation+studies+branch.&rft.au=Kazzi%2C+Ziad+N%3BNemhauser%2C+Jeffrey+B%3BAnsari%2C+Armin%3BMcCurley%2C+Carol%3BWhitcomb%2C+Robert%3BMiller%2C+Charles&rft.aulast=Kazzi&rft.aufirst=Ziad&rft.date=2010-06-01&rft.volume=6&rft.issue=2&rft.spage=230&rft.isbn=&rft.btitle=&rft.title=Journal+of+medical+toxicology+%3A+official+journal+of+the+American+College+of+Medical+Toxicology&rft.issn=15569039&rft_id=info:doi/10.1007%2Fs13181-010-0056-z LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-10-29 N1 - Date created - 2010-08-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1007/s13181-010-0056-z ER - TY - JOUR T1 - Utility of a Commercial Nonstructural Protein 1 Antigen Capture Kit as a Dengue Virus Diagnostic Tool AN - 746302955; 13055752 AB - Annually, over 2.5 billion people are at risk for infection with dengue virus (DENV), while between 50 and 100 million people contract the infection. There is an urgent need for alternative diagnostic tools that can detect DENV during acute infection. Recent studies have shown that DENV nonstructural protein 1 (NS1) is detectable in the blood as early as the onset of symptoms and persists well into the convalescent phase of the infection. We evaluated the utility of the Bio-Rad Platelia DENV NS1 antigen capture kit in combination with real-time reverse transcriptase PCR (RT-PCR) and an IgM antibody capture enzyme-linked immunosorbent assay (MAC-ELISA) for refining a new algorithm for the diagnosis of acute- or convalescent-phase DENV infection with a single clinical sample. We tested the Bio-Rad kit with three panels of sera. These panels were designed to evaluate the sensitivities of the NS1 kit for (i) early-convalescent-phase samples, (ii) acute-phase samples with false-negative PCR results, and (iii) IgM-negative convalescent-phase samples from patients with confirmed secondary DENV infections. Results show that NS1 can be detected in 22% of serum samples collected more than 10 days after the onset of illness and in 22% of samples that did not elicit an IgM response. Additionally, NS1 was detected in 37% of the tested acute-phase samples with false-negative PCR results, suggesting that NS1 detection may be valuable in increasing the sensitivity of current acute-phase diagnostics. These results will improve diagnosis with a single acute-phase or early-convalescent-phase sample for disease surveillance and clinical diagnosis. JF - Clinical and Vaccine Immunology AU - Bessoff, Kovi AU - Phoutrides, Elena AU - Delorey, Mark AU - Acosta, Luz N AU - Hunsperger, Elizabeth AD - Dengue Branch, Centers for Disease Control and Prevention, San Juan, Puerto Rico, enh4@cdc.gov Y1 - 2010/06// PY - 2010 DA - June 2010 SP - 949 EP - 953 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 17 IS - 6 SN - 1556-6811, 1556-6811 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Virology & AIDS Abstracts; Immunology Abstracts KW - Dengue virus KW - Symptoms KW - Enzyme-linked immunosorbent assay KW - Contracts KW - Nucleotide sequence KW - Algorithms KW - Infection KW - Public health KW - Blood KW - Antibodies KW - Antigens KW - Nonstructural proteins KW - DNA KW - RNA-directed DNA polymerase KW - Polymerase chain reaction KW - Vaccines KW - Immunoglobulin M KW - V 22350:Immunology KW - F 06905:Vaccines KW - Q1 08604:Stock assessment and management KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/746302955?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+and+Vaccine+Immunology&rft.atitle=Utility+of+a+Commercial+Nonstructural+Protein+1+Antigen+Capture+Kit+as+a+Dengue+Virus+Diagnostic+Tool&rft.au=Bessoff%2C+Kovi%3BPhoutrides%2C+Elena%3BDelorey%2C+Mark%3BAcosta%2C+Luz+N%3BHunsperger%2C+Elizabeth&rft.aulast=Bessoff&rft.aufirst=Kovi&rft.date=2010-06-01&rft.volume=17&rft.issue=6&rft.spage=949&rft.isbn=&rft.btitle=&rft.title=Clinical+and+Vaccine+Immunology&rft.issn=15566811&rft_id=info:doi/10.1128%2FCVI.00041-10 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Number of references - 23 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Symptoms; Antibodies; Antigens; Contracts; Nucleotide sequence; DNA; Polymerase chain reaction; Vaccines; Public health; Blood; Enzyme-linked immunosorbent assay; Nonstructural proteins; Algorithms; RNA-directed DNA polymerase; Infection; Immunoglobulin M; Dengue virus DO - http://dx.doi.org/10.1128/CVI.00041-10 ER - TY - JOUR T1 - Cloning and Characterization of the Acidic Ribosomal Protein P2 of Cryptosporidium parvum, a New 17-Kilodalton Antigen AN - 746082587; 13055757 AB - Cryptosporidium infection is commonly observed among children and immunocompromised individuals in developing countries, but large-scale outbreaks of disease among adults have not been reported. In contrast, outbreaks of cryptosporidiosis in the United States and Canada are increasingly common among patients of all ages. Thus, it seems likely that residents of regions where Cryptosporidium is highly endemic acquire some level of immunity, while residents of the developed world do not. A new immunodominant Cryptosporidium parvum antigen in the 15- to 17-kDa size range was identified as the Cryptosporidium parvum 60S acidic ribosomal protein P2 (CpP2). We developed a recombinant protein-based enzyme-linked immunosorbent assay for serologic population surveillance for antibodies that was 89% sensitive and 92% specific relative to the results of the large-format Western blot assay. The human IgG response is directed almost exclusively toward the highly conserved, carboxy-terminal 15 amino acids of the protein. Although IgG antibody cross-reactivity was documented with sera from patients with acute babesiosis, the development of an anti-CpP2 antibody response in our Peru study population correlated better with Cryptosporidium infection than with infection by any other parasitic protozoan. In Haiti, the prevalence of antibodies to CpP2 plateaus at 11 to 20 years of age. Because anti-CpP2 IgG antibodies were found only among residents of countries in the developing world where Cryptosporidium infection occurs early and often, we propose that this response may be a proxy for the intensity of infection and for acquired immunity. JF - Clinical and Vaccine Immunology AU - Priest, Jeffrey W AU - Kwon, James P AU - Montgomery, Joel M AU - Bern, Caryn AU - Moss, Delynn M AU - Freeman, Amanda R AU - Jones, Cara C AU - Arrowood, Michael J AU - Won, Kimberly Y AU - Lammie, Patrick J AD - Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, jpriest@cdc.gov Y1 - 2010/06// PY - 2010 DA - Jun 2010 SP - 954 EP - 965 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 17 IS - 6 SN - 1556-679X, 1556-679X KW - Biotechnology and Bioengineering Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology; Biochemistry Abstracts 2: Nucleic Acids; Immunology Abstracts KW - Western blotting KW - Enzyme-linked immunosorbent assay KW - Age KW - Amino acids KW - Cross-reactivity KW - Babesiosis KW - Population studies KW - Antibody response KW - Immunity KW - Infection KW - Children KW - Cryptosporidium parvum KW - Cryptosporidiosis KW - Immunoglobulin G KW - ribosomal protein P2 KW - Developing countries KW - K 03350:Immunology KW - F 06905:Vaccines KW - W 30915:Pharmaceuticals & Vaccines KW - N 14830:RNA UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/746082587?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+and+Vaccine+Immunology&rft.atitle=Cloning+and+Characterization+of+the+Acidic+Ribosomal+Protein+P2+of+Cryptosporidium+parvum%2C+a+New+17-Kilodalton+Antigen&rft.au=Priest%2C+Jeffrey+W%3BKwon%2C+James+P%3BMontgomery%2C+Joel+M%3BBern%2C+Caryn%3BMoss%2C+Delynn+M%3BFreeman%2C+Amanda+R%3BJones%2C+Cara+C%3BArrowood%2C+Michael+J%3BWon%2C+Kimberly+Y%3BLammie%2C+Patrick+J&rft.aulast=Priest&rft.aufirst=Jeffrey&rft.date=2010-06-01&rft.volume=17&rft.issue=6&rft.spage=954&rft.isbn=&rft.btitle=&rft.title=Clinical+and+Vaccine+Immunology&rft.issn=1556679X&rft_id=info:doi/10.1128%2FCVI.00073-10 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-07-01 N1 - Number of references - 81 N1 - Last updated - 2013-12-16 N1 - SubjectsTermNotLitGenreText - Western blotting; Age; Enzyme-linked immunosorbent assay; Cross-reactivity; Amino acids; Babesiosis; Population studies; Immunity; Antibody response; Children; Infection; Cryptosporidiosis; Immunoglobulin G; ribosomal protein P2; Developing countries; Cryptosporidium parvum DO - http://dx.doi.org/10.1128/CVI.00073-10 ER - TY - JOUR T1 - Chemical risk assessment and uncertainty associated with extrapolation across exposure duration AN - 746002769; 13030635 AB - The Agency for Toxic Substances and Disease Registry (ATSDR) prepares toxicological profiles on priority substances in which available epidemiologic and toxicologic data are reviewed, summarized, and interpreted. When adequate data are available, ATSDR derives health guidance values called minimal risk levels (MRLs) for acute, intermediate, and chronic durations of exposure for oral and inhalation routes of exposure. The MRLs are generally derived by use of the no-observed-adverse-effect level (NOAEL) or the lowest-observed-adverse-effect level/uncertainty factor (LOAEL/UF) approach. The UF usually employed are for LOAEL-to-NOAEL extrapolation, animal to -human extrapolation, and inter-human variability. These health guidance values are intended to serve as screening tools for health assessors and other responders to identify contaminants of concern and potential health effects in the community at hazardous waste sites and during unplanned releases. When guidance values are not available for a specific exposure scenario because of a lack of chronic data, extrapolation across exposure durations may be made. For example, chronic guidance values may be derived from subchronic data by applying an additional uncertainty factor of 10 for extrapolation to chronic exposure duration. In this paper, we analyzed the ratio of chemical-specific LOAELs from acute to intermediate and from intermediate to chronic durations for oral and inhalation exposure routes. In addition, we investigated the impact of chemical structure and chemical structure activity relationship on validation of predictions across exposure durations. JF - Regulatory Toxicology and Pharmacology AU - Pohl, H R AU - Chou, C-HSJ AU - Ruiz, P AU - Holler, J S AD - Agency for Toxic Substances and Disease Registry, US Department of Health and Human Services, Atlanta, GA, USA, hpohl@cdc.gov Y1 - 2010/06// PY - 2010 DA - Jun 2010 SP - 18 EP - 23 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 57 IS - 1 SN - 0273-2300, 0273-2300 KW - Pollution Abstracts; Environment Abstracts; Risk Abstracts; Toxicology Abstracts KW - Chronic exposure KW - Inhalation KW - Data processing KW - X 24310:Pharmaceuticals KW - R2 23060:Medical and environmental health KW - P 4000:WASTE MANAGEMENT KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/746002769?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Regulatory+Toxicology+and+Pharmacology&rft.atitle=Chemical+risk+assessment+and+uncertainty+associated+with+extrapolation+across+exposure+duration&rft.au=Pohl%2C+H+R%3BChou%2C+C-HSJ%3BRuiz%2C+P%3BHoller%2C+J+S&rft.aulast=Pohl&rft.aufirst=H&rft.date=2010-06-01&rft.volume=57&rft.issue=1&rft.spage=18&rft.isbn=&rft.btitle=&rft.title=Regulatory+Toxicology+and+Pharmacology&rft.issn=02732300&rft_id=info:doi/10.1016%2Fj.yrtph.2009.11.007 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Data processing; Inhalation DO - http://dx.doi.org/10.1016/j.yrtph.2009.11.007 ER - TY - JOUR T1 - Randomized Trial of the Effects of Housing Assistance on the Health and Risk Behaviors of Homeless and Unstably Housed People Living with HIV AN - 744588516; 12851588 AB - Homelessness affects HIV risk and health, but little is known about the longitudinal effects of rental assistance on the housing status and health of homeless and unstably housed people living with HIV/AIDS. Homeless/unstably housed people living with HIV/AIDS (N=630) were randomly assigned to immediate Housing Opportunities for People with AIDS (HOPWA) rental assistance or customary care. Self-reported data, CD4, and HIV viral load were collected at baseline, 6, 12, and 18months. Results showed that housing status improved in both groups, with greater improvement occurring in the treatment group. At 18months, 51% of the comparison group had their own housing, limiting statistical power. Intent-to-treat analyses demonstrated significant reductions in medical care utilization and improvements in self-reported physical and mental health; significant differential change benefiting the treatment group was observed for depression and perceived stress. Significant differences between homeless and stably housed participants were found in as-treated analyses for health care utilization, mental health, and physical health. HOPWA rental assistance improves housing status and, in some cases, health outcomes of homeless and unstably housed people living with HIV/AIDS. JF - AIDS and Behavior AU - Wolitski, Richard J AU - Kidder, Daniel P AU - Pals, Sherri L AU - Royal, Scott AU - Aidala, Angela AU - Stall, Ron AU - Holtgrave, David R AU - Harre, David AU - Courtenay-Quirk, Cari AD - Division of HIV/AIDS Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton RD NE (E-35), Atlanta, GA, USA, RWolitski@cdc.gov Y1 - 2010/06// PY - 2010 DA - Jun 2010 SP - 493 EP - 503 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 14 IS - 3 SN - 1090-7165, 1090-7165 KW - Risk Abstracts; Virology & AIDS Abstracts KW - Acquired immune deficiency syndrome KW - Data processing KW - Statistics KW - Depression KW - Housing KW - Stress KW - Homelessness KW - Mental disorders KW - CD4 antigen KW - Health care KW - Behavior KW - Human immunodeficiency virus KW - Perception KW - mental disorders KW - V 22360:AIDS and HIV KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/744588516?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Randomized+Trial+of+the+Effects+of+Housing+Assistance+on+the+Health+and+Risk+Behaviors+of+Homeless+and+Unstably+Housed+People+Living+with+HIV&rft.au=Wolitski%2C+Richard+J%3BKidder%2C+Daniel+P%3BPals%2C+Sherri+L%3BRoyal%2C+Scott%3BAidala%2C+Angela%3BStall%2C+Ron%3BHoltgrave%2C+David+R%3BHarre%2C+David%3BCourtenay-Quirk%2C+Cari&rft.aulast=Wolitski&rft.aufirst=Richard&rft.date=2010-06-01&rft.volume=14&rft.issue=3&rft.spage=493&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-009-9643-x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - CD4 antigen; Mental disorders; Acquired immune deficiency syndrome; Depression; Statistics; Data processing; Housing; Stress; Behavior; Health care; Perception; Human immunodeficiency virus; mental disorders; Homelessness DO - http://dx.doi.org/10.1007/s10461-009-9643-x ER - TY - JOUR T1 - Transportation-Related Hazardous Materials Incidents and the Role of Poison Control Centers AN - 742730827; 201018722 AB - Department of Transportation (DOT) mandates reporting of all serious hazardous materials incidents. Hazardous material exposures may result in secondary contamination of emergency departments, or delayed clinical effects. Poison control centers specialize in the management of patients exposed to toxic substances; however, poison control center notification is not required. Purpose The objective is to determine the frequency of poison control center notification after serious hazardous materials incidents when patients were transported to a hospital. Methods A retrospective analysis was conducted of serious hazardous materials incidents as reported by DOT, matched with data from the American Association of Poison Control Centers from 2002 through 2006 that involved patient transport. Incidents were divided into four groups: those reported to a poison control center within 0-360 minutes of the incident; those reported within 361-1440 minutes of the incident; those reported within 1441-4320 minutes of the incident; and no poison control center notification. Analyses were performed on variables including date, time, substance, and time to notification. Data were received in January 2008. Results One hundred fifty-four serious incidents met inclusion criteria. One hundred thirty-four incidents (87%) occurred without poison control center notification. Poison control centers were notified in 20 incidents (12.9%); 15 incidents (9.7%) were reported within 0-360 minutes of the incident (M=115 minutes, range=5-359 minutes); four incidents (2.6%) were reported within 361-1440 minutes of the incident (M=652 minutes, range=566-750 minutes); and one incident (0.7%) was reported after 4320 minutes following the incident. Conclusions Most serious hazardous materials incidents involving patient transport are not reported to poison control centers. Opportunities exist to increase utilization of poison control center resources without increasing financial burdens of the hazardous materials incident. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Sutter, Mark E AU - Hon, Stephanie L AU - Chang, Arthur S AU - Schwartz, Michael D AU - Algren, D Adam AU - Schier, Joshua G AU - Lando, James AU - Lewis, Lauren S AD - National Center for Environmental Health, CDC, Chamblee, Georgia Y1 - 2010/06// PY - 2010 DA - June 2010 SP - 663 EP - 666 PB - Elsevier Science, New York NY VL - 38 IS - 6 SN - 0749-3797, 0749-3797 KW - Transport KW - Hazardous waste disposal KW - Road accidents KW - Notification KW - Poison centres KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742730827?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Transportation-Related+Hazardous+Materials+Incidents+and+the+Role+of+Poison+Control+Centers&rft.au=Sutter%2C+Mark+E%3BHon%2C+Stephanie+L%3BChang%2C+Arthur+S%3BSchwartz%2C+Michael+D%3BAlgren%2C+D+Adam%3BSchier%2C+Joshua+G%3BLando%2C+James%3BLewis%2C+Lauren+S&rft.aulast=Sutter&rft.aufirst=Mark&rft.date=2010-06-01&rft.volume=38&rft.issue=6&rft.spage=663&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2010.02.011 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-10-21 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Notification; Poison centres; Road accidents; Hazardous waste disposal; Transport DO - http://dx.doi.org/10.1016/j.amepre.2010.02.011 ER - TY - JOUR T1 - Youth Assets and Sexual Risk Behavior: Differences Between Male and Female Adolescents AN - 742718720; 201017612 AB - Youth internal assets and external resources are protective factors that can help youth avoid potentially harmful behaviors. This study investigates how the relationship between youth assets or resources and two sexual risk behaviors (ever had sex and birth control use) varied by gender. Data were collected through in-home interviews from parent-adolescent dyads, including 1,219 females and 1,116 males. Important differences exist between male and female adolescents. Females with the nonparental role models or the family communication resource were more likely to report never having had sexual intercourse than were females without the resources. Among males, the aspirations for the future and responsible choices assets were associated with never having had sexual intercourse. Males and females had two assets or resources in common that were protective of never having had sex: peer role models and use of time (religion). Considering which youth assets and resources are more likely to positively influence sexual behaviors of males and females may be important when planning prevention programs with youth. [Reprinted by permission of Sage Publications Inc., copyright, the Society for Public Health Education.] JF - Health Education & Behavior AU - Mueller, Trisha AU - Gavin, Lorrie AU - Oman, Roy AU - Vesely, Sara AU - Aspy, Cheryl AU - Tolma, Eleni AU - Rodine, Sharon AD - Centers for Disease Control and Prevention, Atlanta, Georgia tmueller@cdc.gov Y1 - 2010/06// PY - 2010 DA - June 2010 SP - 343 EP - 356 PB - Sage Publications, Thousand Oaks CA VL - 37 IS - 3 SN - 1090-1981, 1090-1981 KW - adolescents youth assets sexual behavior sex differences KW - Assets KW - Men KW - Gender differences KW - Sexual intercourse KW - Adolescents KW - Role models KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742718720?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+Education+%26+Behavior&rft.atitle=Youth+Assets+and+Sexual+Risk+Behavior%3A+Differences+Between+Male+and+Female+Adolescents&rft.au=Mueller%2C+Trisha%3BGavin%2C+Lorrie%3BOman%2C+Roy%3BVesely%2C+Sara%3BAspy%2C+Cheryl%3BTolma%2C+Eleni%3BRodine%2C+Sharon&rft.aulast=Mueller&rft.aufirst=Trisha&rft.date=2010-06-01&rft.volume=37&rft.issue=3&rft.spage=343&rft.isbn=&rft.btitle=&rft.title=Health+Education+%26+Behavior&rft.issn=10901981&rft_id=info:doi/10.1177%2F1090198109344689 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-10-21 N1 - Last updated - 2016-09-27 N1 - CODEN - HEDBFS N1 - SubjectsTermNotLitGenreText - Assets; Gender differences; Men; Role models; Sexual intercourse; Adolescents DO - http://dx.doi.org/10.1177/1090198109344689 ER - TY - JOUR T1 - Detection and differentiation of Clostridium botulinum type A strains using a focused DNA microarray. AN - 733914016; 20056143 AB - A focused oligonucleotide microarray featuring 62 probes targeting strain variable regions of the Clostridium botulinum strain ATCC 3502 genome sequence was developed to differentiate C. botulinum type A strains. The strain variable regions were selected from deletions identified among a panel of 10 type A strains compared to the strain ATCC 3502 genome sequence using high density comparative genomic hybridization microarrays. The focused microarray also featured specific probes for the detection of the neurotoxin genes of various serotypes (A-G), toxin gene cluster components (ha70 and orfX1), and fldB as a marker for proteolytic clostridia (Group I). Eight pairs of strains selected from separate type A botulism outbreaks were included in the 27 subtype A1-A4 strains examined in this study. Each outbreak related strain pair consisted of strains isolated from different sources (stool and food). Of the eight outbreak related strain pairs, six groups of strains with indistinguishable hybridization patterns were identified. Outbreak related strains were shown to have identical hybridization patterns. Strain pairs from three separate outbreaks involving strains harboring both the type A neurotoxin gene (bont/A) and an unexpressed type B neurotoxin gene (bont/B) shared the same probe hybridization profile. The focused microarray format provides a rapid approach for neurotoxin gene detection and preliminary determination of the relatedness of strains isolated from different sources. JF - Molecular and cellular probes AU - Raphael, Brian H AU - Joseph, Lavin A AU - McCroskey, Loretta M AU - Lúquez, Carolina AU - Maslanka, Susan E AD - Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA. elx9@cdc.gov Y1 - 2010/06// PY - 2010 DA - June 2010 SP - 146 EP - 153 VL - 24 IS - 3 KW - Bacterial Proteins KW - 0 KW - DNA Probes KW - DNA, Bacterial KW - Neurotoxins KW - Index Medicus KW - Polymerase Chain Reaction KW - DNA Probes -- genetics KW - Botulism -- microbiology KW - DNA, Bacterial -- chemistry KW - Humans KW - DNA, Bacterial -- genetics KW - Microarray Analysis -- methods KW - Sequence Analysis, DNA KW - Species Specificity KW - Bacterial Proteins -- genetics KW - Neurotoxins -- genetics KW - Clostridium botulinum type A -- isolation & purification KW - Clostridium botulinum type A -- classification KW - Comparative Genomic Hybridization -- methods KW - Clostridium botulinum type A -- genetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733914016?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Molecular+and+cellular+probes&rft.atitle=Detection+and+differentiation+of+Clostridium+botulinum+type+A+strains+using+a+focused+DNA+microarray.&rft.au=Raphael%2C+Brian+H%3BJoseph%2C+Lavin+A%3BMcCroskey%2C+Loretta+M%3BL%C3%BAquez%2C+Carolina%3BMaslanka%2C+Susan+E&rft.aulast=Raphael&rft.aufirst=Brian&rft.date=2010-06-01&rft.volume=24&rft.issue=3&rft.spage=146&rft.isbn=&rft.btitle=&rft.title=Molecular+and+cellular+probes&rft.issn=1096-1194&rft_id=info:doi/10.1016%2Fj.mcp.2009.12.003 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-08-10 N1 - Date created - 2010-04-26 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.mcp.2009.12.003 ER - TY - JOUR T1 - Lead poisoning among internally displaced Roma, Ashkali and Egyptian children in the United Nations-Administered Province of Kosovo. AN - 733316699; 19897587 AB - This study assessed the association between lead poisoning prevention activities and blood lead levels (BLLs) among children living in lead-contaminated camps for internally displaced persons in the United Nations-Administered Province of Kosovo. We conducted a population-based study to examine the relationship among geometric mean BLLs in children (i) born before any lead poisoning prevention activities were instituted, (ii) born when specific interim interventions were instituted and (iii) born after relocation and medical therapy were available. The study population consisted of 145 of the 186 children born in the camps between December 1999 and July 2007. Lower mean BLLs were found in children born following implementation of the interventions as compared with the children born before the interventions. However, this decrease in mean BLLs was attenuated in children born into families suspected of informal lead smelting. Despite lower BLLs following interventions, children living in these camps have BLLs that remain unacceptably high. Further efforts are urgently needed to control or eliminate lead exposure in this population. Continued blood lead monitoring of the population is also warranted. JF - European journal of public health AU - Brown, Mary Jean AU - McWeeney, Gerry AU - Kim, Rokho AU - Tahirukaj, Ardita AU - Bulat, Petar AU - Syla, Skender AU - Savic, Zoran AU - Amitai, Yona AU - Dignam, Timothy AU - Kaluski, Dorit Nitzan AD - Lead Poisoning Prevention Branch, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30348, USA. mjb5@cdc.gov Y1 - 2010/06// PY - 2010 DA - June 2010 SP - 288 EP - 292 VL - 20 IS - 3 KW - Lead KW - 2P299V784P KW - Index Medicus KW - Metallurgy -- methods KW - Blood Chemical Analysis KW - Egypt -- ethnology KW - Humans KW - Slovakia -- ethnology KW - Child KW - Residence Characteristics -- statistics & numerical data KW - Child, Preschool KW - Population Surveillance KW - Yugoslavia -- epidemiology KW - Environmental Exposure -- adverse effects KW - Female KW - Male KW - Lead Poisoning -- prevention & control KW - Lead Poisoning -- ethnology KW - Transients and Migrants -- statistics & numerical data KW - Lead -- blood UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733316699?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=European+journal+of+public+health&rft.atitle=Lead+poisoning+among+internally+displaced+Roma%2C+Ashkali+and+Egyptian+children+in+the+United+Nations-Administered+Province+of+Kosovo.&rft.au=Brown%2C+Mary+Jean%3BMcWeeney%2C+Gerry%3BKim%2C+Rokho%3BTahirukaj%2C+Ardita%3BBulat%2C+Petar%3BSyla%2C+Skender%3BSavic%2C+Zoran%3BAmitai%2C+Yona%3BDignam%2C+Timothy%3BKaluski%2C+Dorit+Nitzan&rft.aulast=Brown&rft.aufirst=Mary&rft.date=2010-06-01&rft.volume=20&rft.issue=3&rft.spage=288&rft.isbn=&rft.btitle=&rft.title=European+journal+of+public+health&rft.issn=1464-360X&rft_id=info:doi/10.1093%2Feurpub%2Fckp164 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-11-22 N1 - Date created - 2010-05-17 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1093/eurpub/ckp164 ER - TY - JOUR T1 - Effect of differing levels of tobacco-specific nitrosamines in cigarette smoke on the levels of biomarkers in smokers. AN - 733250414; 20501750 AB - Smokers are exposed to significant doses of carcinogens, including tobacco-specific nitrosamines (TSNA). Previous studies have shown significant global differences in the levels of TSNAs in cigarette smoke because of the variation in tobacco blending and curing practices around the world. Mouth-level exposure to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) measured in cigarette butts and urinary concentrations of its major metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) were examined among 126 daily smokers in four countries over a 24-hour study period. As mouth-level exposure of NNK increased, the urinary NNAL increased even after adjustment for other covariates (beta = 0.46, P = 0.004). The relationship between mouth-level exposure to nicotine and its salivary metabolite, cotinine, was not statistically significant (beta = 0.29, P = 0.057), likely because of the very limited range of differences in mouth-level nicotine exposure in this population. We have shown a direct association between the 24-hour mouth-level exposure of NNK resulting from cigarette smoking and the concentration of its primary metabolite, NNAL, in the urine of smokers. Internal dose concentrations of urinary NNAL are significantly lower in smokers in countries that have lower TSNA levels in cigarettes such as Canada and Australia in contrast to countries that have high levels of these carcinogens in cigarettes, such as the United States. Lowering the levels of NNK in the mainstream smoke of cigarettes through the use of specific tobacco types and known curing practices can significantly affect the exposure of smokers to this known carcinogen. Copyright 2010 AACR. JF - Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology AU - Ashley, David L AU - O'Connor, Richard J AU - Bernert, John T AU - Watson, Clifford H AU - Polzin, Gregory M AU - Jain, Ram B AU - Hammond, David AU - Hatsukami, Dorothy K AU - Giovino, Gary A AU - Cummings, K Michael AU - McNeill, Ann AU - Shahab, Lion AU - King, Bill AU - Fong, Geoffrey T AU - Zhang, Liqin AU - Xia, Yang AU - Yan, Xizheng AU - McCraw, Joan M AD - Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA. dla1@cdc.gov Y1 - 2010/06// PY - 2010 DA - June 2010 SP - 1389 EP - 1398 VL - 19 IS - 6 KW - 4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol KW - 0 KW - Biomarkers KW - Nitrosamines KW - Pyridines KW - Nicotine KW - 6M3C89ZY6R KW - 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone KW - 7S395EDO61 KW - Cotinine KW - K5161X06LL KW - Index Medicus KW - Young Adult KW - Pyridines -- analysis KW - Humans KW - Biomarkers -- urine KW - Tobacco -- chemistry KW - Nicotine -- metabolism KW - Adult KW - Biomarkers -- metabolism KW - Saliva -- metabolism KW - Middle Aged KW - Adolescent KW - Pyridines -- metabolism KW - Female KW - Male KW - Cotinine -- metabolism KW - Smoking -- urine KW - Nitrosamines -- urine KW - Nitrosamines -- metabolism KW - Smoking -- metabolism KW - Nitrosamines -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733250414?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cancer+epidemiology%2C+biomarkers+%26+prevention+%3A+a+publication+of+the+American+Association+for+Cancer+Research%2C+cosponsored+by+the+American+Society+of+Preventive+Oncology&rft.atitle=Effect+of+differing+levels+of+tobacco-specific+nitrosamines+in+cigarette+smoke+on+the+levels+of+biomarkers+in+smokers.&rft.au=Ashley%2C+David+L%3BO%27Connor%2C+Richard+J%3BBernert%2C+John+T%3BWatson%2C+Clifford+H%3BPolzin%2C+Gregory+M%3BJain%2C+Ram+B%3BHammond%2C+David%3BHatsukami%2C+Dorothy+K%3BGiovino%2C+Gary+A%3BCummings%2C+K+Michael%3BMcNeill%2C+Ann%3BShahab%2C+Lion%3BKing%2C+Bill%3BFong%2C+Geoffrey+T%3BZhang%2C+Liqin%3BXia%2C+Yang%3BYan%2C+Xizheng%3BMcCraw%2C+Joan+M&rft.aulast=Ashley&rft.aufirst=David&rft.date=2010-06-01&rft.volume=19&rft.issue=6&rft.spage=1389&rft.isbn=&rft.btitle=&rft.title=Cancer+epidemiology%2C+biomarkers+%26+prevention+%3A+a+publication+of+the+American+Association+for+Cancer+Research%2C+cosponsored+by+the+American+Society+of+Preventive+Oncology&rft.issn=1538-7755&rft_id=info:doi/10.1158%2F1055-9965.EPI-10-0084 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-10-15 N1 - Date created - 2010-06-09 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Erratum In: Cancer Epidemiol Biomarkers Prev. 2010 Sep;19(9):2416 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1158/1055-9965.EPI-10-0084 ER - TY - JOUR T1 - Workers with Libby amphibole exposure: retrospective identification and progression of radiographic changes. AN - 733106862; 20501730 AB - To assess how early pleural and/or parenchymal abnormalities consistent with asbestos exposure could be ascertained and to identify factors associated with progression. Informed consent was obtained under an institutional review board-approved protocol. Multiple sequential chest radiographs obtained between 1955 and 2004 in 84 workers exposed to amphiboles associated with vermiculite in the town of Libby, Montana, were studied. A panel of three NIOSH B readers reviewed each worker's longitudinal chest radiograph series in reverse chronologic order and achieved a consensus reading for each radiograph. Measures of exposure were compared between workers with and those without progression of parenchymal and pleural abnormalities. Because of the way the study was designed, all subjects had pleural (n = 84) and/or parenchymal (n = 26) abnormalities on the most recent chest radiograph. Compared with other investigations that used different methods, this investigation revealed shorter latency periods (defined as the interval between date of hire and date of earliest radiographic detection) for circumscribed pleural plaque (median latency, 8.6 years) and pleural calcification (median latency, 17.5 years). Pleural abnormalities progressed in 64 workers, while parenchymal abnormalities progressed in 14. No significant differences were found with regard to measures of exposure between workers with and those without progression. The latency period for the development of pleural plaques may be shorter than previously reported. Early plaques are subtle and may not be detectable except at retrospective review. Copyright RSNA, 2010 JF - Radiology AU - Larson, Theodore C AU - Meyer, Cristopher A AU - Kapil, Vikas AU - Gurney, Jud W AU - Tarver, Robert D AU - Black, Charles B AU - Lockey, James E AD - Division of Health Studies, Agency for Toxic Substances and Disease Registry, 4770 Buford Hwy NE, MS F57, Atlanta, GA 30341, USA. thl3@cdc.gov Y1 - 2010/06// PY - 2010 DA - June 2010 SP - 924 EP - 933 VL - 255 IS - 3 KW - Asbestos, Amphibole KW - 0 KW - Abridged Index Medicus KW - Index Medicus KW - Logistic Models KW - Humans KW - Montana -- epidemiology KW - Adult KW - Retrospective Studies KW - Disease Progression KW - Middle Aged KW - Statistics, Nonparametric KW - Male KW - Radiography, Thoracic KW - Asbestos, Amphibole -- toxicity KW - Occupational Diseases -- diagnostic imaging KW - Occupational Exposure -- adverse effects KW - Occupational Diseases -- epidemiology KW - Pleural Diseases -- diagnostic imaging KW - Pleural Diseases -- epidemiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733106862?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Radiology&rft.atitle=Workers+with+Libby+amphibole+exposure%3A+retrospective+identification+and+progression+of+radiographic+changes.&rft.au=Larson%2C+Theodore+C%3BMeyer%2C+Cristopher+A%3BKapil%2C+Vikas%3BGurney%2C+Jud+W%3BTarver%2C+Robert+D%3BBlack%2C+Charles+B%3BLockey%2C+James+E&rft.aulast=Larson&rft.aufirst=Theodore&rft.date=2010-06-01&rft.volume=255&rft.issue=3&rft.spage=924&rft.isbn=&rft.btitle=&rft.title=Radiology&rft.issn=1527-1315&rft_id=info:doi/10.1148%2Fradiol.10091447 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-07-15 N1 - Date created - 2010-05-26 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Comment In: Radiology. 2010 Jun;255(3):681-2 [20501707] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1148/radiol.10091447 ER - TY - JOUR T1 - Semi-volatiles in mainstream smoke delivery from select charcoal-filtered cigarette brand variants. AN - 733106485; 20501495 AB - It has been reported that charcoal added to cigarette filters selectively removes many of the more volatile chemicals, but it is not clear to what extent charcoal may reduce the delivery of important less volatile chemical constituents in mainstream cigarette smoke. We analysed machine-derived mainstream smoke deliveries (under three smoking regimens) for variants of a charcoal-filtered cigarette commercially test-marketed in the USA, focusing on selected polycyclic aromatic hydrocarbons (PAHs), phenols and tobacco-specific nitrosamines (TSNAs). While charcoal-containing filters selectively removed lower molecular weight PAHs from mainstream smoke, they did not significantly remove the heavier and more toxic PAHs studied, such as benzo[a]pyrene, a known carcinogen. Likewise, charcoal-containing filters removed phenols and TSNAs from mainstream smoke to differing amounts depending on the compound, filter design and the smoking regimen. The addition of sufficient charcoal to cigarette filters is known to remove many volatile compounds and can potentially reduce deliveries of certain semi-volatile compounds under some machine smoking regimens. Less volatile compounds, with a significant portion in the particulate phase, are less available for selective filtration by charcoal-containing filters than the more volatile compounds that reside predominantly in the gas phase. JF - Tobacco control AU - Hearn, Bryan A AU - Ding, Yan S AU - Vaughan, Christina AU - Zhang, Liqin AU - Polzin, Gregory AU - Caudill, Samuel P AU - Watson, Clifford H AU - Ashley, David L AD - Emergency Response and Air Toxicants Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway, NE MS F-47, Atlanta, GA 30341, USA. bhearn@cdc.gov Y1 - 2010/06// PY - 2010 DA - June 2010 SP - 223 EP - 230 VL - 19 IS - 3 KW - Carcinogens KW - 0 KW - Nitrosamines KW - Phenols KW - Polycyclic Aromatic Hydrocarbons KW - Smoke KW - Charcoal KW - 16291-96-6 KW - Nicotine KW - 6M3C89ZY6R KW - Index Medicus KW - Humans KW - Nicotine -- analysis KW - Carcinogens -- analysis KW - Inhalation Exposure -- adverse effects KW - Smoking KW - Filtration -- methods KW - Tobacco -- chemistry KW - Polycyclic Aromatic Hydrocarbons -- analysis KW - Smoke -- analysis KW - Nitrosamines -- analysis KW - Phenols -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733106485?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Tobacco+control&rft.atitle=Semi-volatiles+in+mainstream+smoke+delivery+from+select+charcoal-filtered+cigarette+brand+variants.&rft.au=Hearn%2C+Bryan+A%3BDing%2C+Yan+S%3BVaughan%2C+Christina%3BZhang%2C+Liqin%3BPolzin%2C+Gregory%3BCaudill%2C+Samuel+P%3BWatson%2C+Clifford+H%3BAshley%2C+David+L&rft.aulast=Hearn&rft.aufirst=Bryan&rft.date=2010-06-01&rft.volume=19&rft.issue=3&rft.spage=223&rft.isbn=&rft.btitle=&rft.title=Tobacco+control&rft.issn=1468-3318&rft_id=info:doi/10.1136%2Ftc.2009.032680 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-09-02 N1 - Date created - 2010-05-26 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1136/tc.2009.032680 ER - TY - CPAPER T1 - Malaria and Travel. T2 - 110th General Meeting of the American Society for Microbiology AN - 839652259; 5893688 JF - 110th General Meeting of the American Society for Microbiology AU - Townes, D Y1 - 2010/05/23/ PY - 2010 DA - 2010 May 23 KW - {Q1} KW - Malaria KW - Travel KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839652259?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=Malaria+and+Travel.&rft.au=Townes%2C+D&rft.aulast=Townes&rft.aufirst=D&rft.date=2010-05-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://gm.asm.org/images/stories/final_gm_final_program-v2.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-11 N1 - Last updated - 2011-01-14 ER - TY - CPAPER T1 - Careers at the CDC T2 - 110th General Meeting of the American Society for Microbiology AN - 839651576; 5893780 JF - 110th General Meeting of the American Society for Microbiology AU - Kozak, N Y1 - 2010/05/23/ PY - 2010 DA - 2010 May 23 KW - {Q1} KW - Careers KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839651576?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=Careers+at+the+CDC&rft.au=Kozak%2C+N&rft.aulast=Kozak&rft.aufirst=N&rft.date=2010-05-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://gm.asm.org/images/stories/final_gm_final_program-v2.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-11 N1 - Last updated - 2011-01-14 ER - TY - CPAPER T1 - Gen-Probe Joseph Public Health Award - Partners, Prevention, and Public Health: A Journey Through Infectious Disease Ecology T2 - 110th General Meeting of the American Society for Microbiology AN - 839650851; 5893689 JF - 110th General Meeting of the American Society for Microbiology AU - Miller, J Y1 - 2010/05/23/ PY - 2010 DA - 2010 May 23 KW - {Q1} KW - Public health KW - Awards KW - Ecology KW - Prevention KW - Infectious diseases KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839650851?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=Gen-Probe+Joseph+Public+Health+Award+-+Partners%2C+Prevention%2C+and+Public+Health%3A+A+Journey+Through+Infectious+Disease+Ecology&rft.au=Miller%2C+J&rft.aulast=Miller&rft.aufirst=J&rft.date=2010-05-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://gm.asm.org/images/stories/final_gm_final_program-v2.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-11 N1 - Last updated - 2011-01-14 ER - TY - CPAPER T1 - Sustained T cell Dependent Cytokine Responses Induced by Infection with Coxiella burnetii T2 - 110th General Meeting of the American Society for Microbiology AN - 839650832; 5894019 JF - 110th General Meeting of the American Society for Microbiology AU - Kersh, G AU - Self, J AU - Oliver, L AU - Fitzpatrick, K AU - Massung, R Y1 - 2010/05/23/ PY - 2010 DA - 2010 May 23 KW - {Q1} KW - Infection KW - Cytokines KW - Lymphocytes T KW - {Q2} KW - Coxiella burnetii KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839650832?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=Sustained+T+cell+Dependent+Cytokine+Responses+Induced+by+Infection+with+Coxiella+burnetii&rft.au=Kersh%2C+G%3BSelf%2C+J%3BOliver%2C+L%3BFitzpatrick%2C+K%3BMassung%2C+R&rft.aulast=Kersh&rft.aufirst=G&rft.date=2010-05-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://gm.asm.org/images/stories/final_gm_final_program-v2.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-11 N1 - Last updated - 2011-01-14 ER - TY - CPAPER T1 - An Immunofiltration Device for the Simultaneous Detection of Nontreponemal and Treponemal Antibodies in Patients with Syphilis T2 - 110th General Meeting of the American Society for Microbiology AN - 839650222; 5893583 JF - 110th General Meeting of the American Society for Microbiology AU - Castro, A AU - Mody, H AU - Parab, S AU - Patel, M AU - Kikkert, S AU - Ballard, R AU - Park, M Y1 - 2010/05/23/ PY - 2010 DA - 2010 May 23 KW - {Q1} KW - Syphilis KW - Antibodies KW - {Q2} KW - Treponema pallidum KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839650222?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=An+Immunofiltration+Device+for+the+Simultaneous+Detection+of+Nontreponemal+and+Treponemal+Antibodies+in+Patients+with+Syphilis&rft.au=Castro%2C+A%3BMody%2C+H%3BParab%2C+S%3BPatel%2C+M%3BKikkert%2C+S%3BBallard%2C+R%3BPark%2C+M&rft.aulast=Castro&rft.aufirst=A&rft.date=2010-05-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://gm.asm.org/images/stories/final_gm_final_program-v2.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-11 N1 - Last updated - 2011-01-14 ER - TY - CPAPER T1 - Development of a Multilocus Microsatellite Typing Scheme for Rhizopus oryzae and Its Utility in Molecular Epidemiology T2 - 110th General Meeting of the American Society for Microbiology AN - 839648060; 5893607 JF - 110th General Meeting of the American Society for Microbiology AU - Etienne, K AU - Gibbons, J AU - Waybrant, T AU - Balajee, S Y1 - 2010/05/23/ PY - 2010 DA - 2010 May 23 KW - {Q1} KW - Typing KW - Microsatellites KW - Epidemiology KW - {Q2} KW - Rhizopus oryzae KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839648060?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=Development+of+a+Multilocus+Microsatellite+Typing+Scheme+for+Rhizopus+oryzae+and+Its+Utility+in+Molecular+Epidemiology&rft.au=Etienne%2C+K%3BGibbons%2C+J%3BWaybrant%2C+T%3BBalajee%2C+S&rft.aulast=Etienne&rft.aufirst=K&rft.date=2010-05-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://gm.asm.org/images/stories/final_gm_final_program-v2.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-11 N1 - Last updated - 2011-01-14 ER - TY - CPAPER T1 - Performance of Bacteriology Proficiency Testing in the U.S. from 2003-2008 T2 - 110th General Meeting of the American Society for Microbiology AN - 839647921; 5893240 JF - 110th General Meeting of the American Society for Microbiology AU - Stang, H AU - Kuehl, D AU - Carey, R AU - Anderson, N Y1 - 2010/05/23/ PY - 2010 DA - 2010 May 23 KW - {Q1} KW - USA KW - Bacteriology KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839647921?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=Performance+of+Bacteriology+Proficiency+Testing+in+the+U.S.+from+2003-2008&rft.au=Stang%2C+H%3BKuehl%2C+D%3BCarey%2C+R%3BAnderson%2C+N&rft.aulast=Stang&rft.aufirst=H&rft.date=2010-05-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://gm.asm.org/images/stories/final_gm_final_program-v2.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-11 N1 - Last updated - 2011-01-14 ER - TY - CPAPER T1 - Protocol for Detection of Biofilms on Needleless Intravenous Catheter Access Devices and Primary Infusion Lines T2 - 110th General Meeting of the American Society for Microbiology AN - 839647095; 5895168 JF - 110th General Meeting of the American Society for Microbiology AU - Perez, E AU - Jacob, J AU - Steinberg, J P AU - Donlan, R Y1 - 2010/05/23/ PY - 2010 DA - 2010 May 23 KW - {Q1} KW - Medical instruments KW - Biofilms KW - Intravenous administration KW - Catheters KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839647095?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=Protocol+for+Detection+of+Biofilms+on+Needleless+Intravenous+Catheter+Access+Devices+and+Primary+Infusion+Lines&rft.au=Perez%2C+E%3BJacob%2C+J%3BSteinberg%2C+J+P%3BDonlan%2C+R&rft.aulast=Perez&rft.aufirst=E&rft.date=2010-05-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://gm.asm.org/images/stories/final_gm_final_program-v2.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-11 N1 - Last updated - 2011-01-14 ER - TY - CPAPER T1 - Evaluation of Restriction Enzyme Robustness Over Varying Incubation Times for Salmonella and Escherichia coli PulseNet Standardized Pulsed-Field Gel Electrophoresis Protocols T2 - 110th General Meeting of the American Society for Microbiology AN - 839641820; 5895571 JF - 110th General Meeting of the American Society for Microbiology AU - Halpin, J AU - Ribot, E AU - Cooper, K Y1 - 2010/05/23/ PY - 2010 DA - 2010 May 23 KW - {Q1} KW - Standards KW - Electrophoresis KW - Enzymes KW - Pulsed-field gel electrophoresis KW - Anadromous species KW - Incubation KW - {Q2} KW - Escherichia coli KW - Salmonella KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839641820?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=Evaluation+of+Restriction+Enzyme+Robustness+Over+Varying+Incubation+Times+for+Salmonella+and+Escherichia+coli+PulseNet+Standardized+Pulsed-Field+Gel+Electrophoresis+Protocols&rft.au=Halpin%2C+J%3BRibot%2C+E%3BCooper%2C+K&rft.aulast=Halpin&rft.aufirst=J&rft.date=2010-05-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://gm.asm.org/images/stories/final_gm_final_program-v2.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-11 N1 - Last updated - 2011-01-14 ER - TY - CPAPER T1 - Comparison of Three Molecular Methods for Typing Bordetella pertussis Isolates T2 - 110th General Meeting of the American Society for Microbiology AN - 839641200; 5895583 JF - 110th General Meeting of the American Society for Microbiology AU - Schmidtke, A AU - Tondella, M AU - Cassiday, P AU - Bonkosky, M AU - Tatti, K Y1 - 2010/05/23/ PY - 2010 DA - 2010 May 23 KW - {Q1} KW - Typing KW - Pertussis KW - {Q2} KW - Bordetella pertussis KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839641200?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=Comparison+of+Three+Molecular+Methods+for+Typing+Bordetella+pertussis+Isolates&rft.au=Schmidtke%2C+A%3BTondella%2C+M%3BCassiday%2C+P%3BBonkosky%2C+M%3BTatti%2C+K&rft.aulast=Schmidtke&rft.aufirst=A&rft.date=2010-05-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://gm.asm.org/images/stories/final_gm_final_program-v2.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-11 N1 - Last updated - 2011-01-14 ER - TY - CPAPER T1 - Evaluation of Testing Schemes for the Detection of KPCProducing Enterobacteriaceae T2 - 110th General Meeting of the American Society for Microbiology AN - 839640508; 5892784 JF - 110th General Meeting of the American Society for Microbiology AU - Lonsway, D AU - Wong, B AU - Anderson, K AU - Patel, J Y1 - 2010/05/23/ PY - 2010 DA - 2010 May 23 KW - {Q2} KW - Enterobacteriaceae KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839640508?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=Evaluation+of+Testing+Schemes+for+the+Detection+of+KPCProducing+Enterobacteriaceae&rft.au=Lonsway%2C+D%3BWong%2C+B%3BAnderson%2C+K%3BPatel%2C+J&rft.aulast=Lonsway&rft.aufirst=D&rft.date=2010-05-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://gm.asm.org/images/stories/final_gm_final_program-v2.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-11 N1 - Last updated - 2011-01-14 ER - TY - CPAPER T1 - Sequence-based Typing Analysis of Clinical and Environmental Isolates from Legionnaires' Disease Outbreaks Investigated by the Centers for Disease Control and Prevention (CDC), 1993 - 2009. T2 - 110th General Meeting of the American Society for Microbiology AN - 839640362; 5895586 JF - 110th General Meeting of the American Society for Microbiology AU - Kozak, N AU - Silk, B AU - Brown, E AU - Frace, M AU - Hicks, L AU - Fields, B Y1 - 2010/05/23/ PY - 2010 DA - 2010 May 23 KW - {Q1} KW - Disease control KW - Prevention KW - Legionnaire's disease KW - Outbreaks KW - Typing KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839640362?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=Sequence-based+Typing+Analysis+of+Clinical+and+Environmental+Isolates+from+Legionnaires%27+Disease+Outbreaks+Investigated+by+the+Centers+for+Disease+Control+and+Prevention+%28CDC%29%2C+1993+-+2009.&rft.au=Kozak%2C+N%3BSilk%2C+B%3BBrown%2C+E%3BFrace%2C+M%3BHicks%2C+L%3BFields%2C+B&rft.aulast=Kozak&rft.aufirst=N&rft.date=2010-05-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://gm.asm.org/images/stories/final_gm_final_program-v2.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-11 N1 - Last updated - 2011-01-14 ER - TY - CPAPER T1 - Practical Application of Sequential Multiplex PCR for Routine Pneumococcal Serotype Surveillance T2 - 110th General Meeting of the American Society for Microbiology AN - 839639629; 5895607 JF - 110th General Meeting of the American Society for Microbiology AU - Hulkower, R AU - Gertz, Jr, R AU - Roundtree, A AU - Pimenta, F AU - Carvalho, M AU - Farley, M AU - Beall, B Y1 - 2010/05/23/ PY - 2010 DA - 2010 May 23 KW - {Q1} KW - Serotypes KW - Polymerase chain reaction KW - Nucleotide sequence KW - {Q2} KW - Streptococcus pneumoniae KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839639629?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=Practical+Application+of+Sequential+Multiplex+PCR+for+Routine+Pneumococcal+Serotype+Surveillance&rft.au=Hulkower%2C+R%3BGertz%2C+Jr%2C+R%3BRoundtree%2C+A%3BPimenta%2C+F%3BCarvalho%2C+M%3BFarley%2C+M%3BBeall%2C+B&rft.aulast=Hulkower&rft.aufirst=R&rft.date=2010-05-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://gm.asm.org/images/stories/final_gm_final_program-v2.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-11 N1 - Last updated - 2011-01-14 ER - TY - CPAPER T1 - Surveillance of Vibrio parahaemolyticus Isolates from the United States, 2008. T2 - 110th General Meeting of the American Society for Microbiology AN - 839639329; 5894286 JF - 110th General Meeting of the American Society for Microbiology AU - Garrett, N AU - Humphrys, M AU - Bopp, C Y1 - 2010/05/23/ PY - 2010 DA - 2010 May 23 KW - {Q1} KW - USA KW - Surveillance and enforcement KW - {Q2} KW - Vibrio parahaemolyticus KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839639329?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=Surveillance+of+Vibrio+parahaemolyticus+Isolates+from+the+United+States%2C+2008.&rft.au=Garrett%2C+N%3BHumphrys%2C+M%3BBopp%2C+C&rft.aulast=Garrett&rft.aufirst=N&rft.date=2010-05-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://gm.asm.org/images/stories/final_gm_final_program-v2.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-11 N1 - Last updated - 2011-01-14 ER - TY - CPAPER T1 - Current Pertussis PCR Diagnostic Methods in US. T2 - 110th General Meeting of the American Society for Microbiology AN - 839639097; 5894400 JF - 110th General Meeting of the American Society for Microbiology AU - Tatti, K AU - Martin, S AU - O'Connell, K AU - Brown, K AU - Trabold, P AU - Chiklis, G AU - Clark, T AU - Tondella, M Y1 - 2010/05/23/ PY - 2010 DA - 2010 May 23 KW - {Q1} KW - Polymerase chain reaction KW - Pertussis KW - Nucleotide sequence KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839639097?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=Current+Pertussis+PCR+Diagnostic+Methods+in+US.&rft.au=Tatti%2C+K%3BMartin%2C+S%3BO%27Connell%2C+K%3BBrown%2C+K%3BTrabold%2C+P%3BChiklis%2C+G%3BClark%2C+T%3BTondella%2C+M&rft.aulast=Tatti&rft.aufirst=K&rft.date=2010-05-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://gm.asm.org/images/stories/final_gm_final_program-v2.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-11 N1 - Last updated - 2011-01-14 ER - TY - CPAPER T1 - Integration of Acanthamoeba polyphaga into a Model Multi-species Drinking Water Distribution System Biofilm T2 - 110th General Meeting of the American Society for Microbiology AN - 839631287; 5894175 JF - 110th General Meeting of the American Society for Microbiology AU - O'Connell, H AU - Armbruster, C AU - Donlan, R AU - Williams, M Y1 - 2010/05/23/ PY - 2010 DA - 2010 May 23 KW - {Q1} KW - Drinking water KW - Biofilms KW - Integration KW - {Q2} KW - Acanthamoeba polyphaga KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839631287?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.atitle=Integration+of+Acanthamoeba+polyphaga+into+a+Model+Multi-species+Drinking+Water+Distribution+System+Biofilm&rft.au=O%27Connell%2C+H%3BArmbruster%2C+C%3BDonlan%2C+R%3BWilliams%2C+M&rft.aulast=O%27Connell&rft.aufirst=H&rft.date=2010-05-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=110th+General+Meeting+of+the+American+Society+for+Microbiology&rft.issn=&rft_id=info:doi/ L2 - http://gm.asm.org/images/stories/final_gm_final_program-v2.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-11 N1 - Last updated - 2011-01-14 ER - TY - JOUR T1 - Extensively Drug-Resistant Tuberculosis: "There must be some kind of way out of here" AN - 754541382; 13265367 AB - Over the past 7 decades, Mycobacterium tuberculosis has developed resistance to virtually every new drug used to treat tuberculosis, resulting recently in the global emergence of extensively drug-resistant tuberculosis. In an individual, treatment with a single new drug results in acquired drug resistance within weeks to months. On a population basis, the pattern is just as consistent. After a new drug is introduced, drug-resistant cases or case series are reported within months to years, typically leading to focused surveys, and within several years, dramatic outbreaks with extraordinary mortality occur. Invariably, such outbreaks prove to be the tip of the iceberg. Incomplete and delayed diagnoses, drug costs, and drug supplies are frequently implicated. With new drugs and new diagnostics on the horizon, we must develop new ways of incorporating them into public health practice, basing treatment on rapid drug-susceptibility tests, ensuring that effective drugs are always used in combination, and making these drug available to persons who need them. JF - Clinical Infectious Diseases AU - Cegielski, J P AD - Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Mallstop E-10, Atlanta, GA 30333, USA, gzc2@cdc.gov Y1 - 2010/05/15/ PY - 2010 DA - 2010 May 15 SP - S195 EP - S200 VL - 50 SN - 1058-4838, 1058-4838 KW - Microbiology Abstracts B: Bacteriology KW - Mortality KW - Drug resistance KW - Tuberculosis KW - Drugs KW - Mycobacterium tuberculosis KW - Public health KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754541382?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+Infectious+Diseases&rft.atitle=Extensively+Drug-Resistant+Tuberculosis%3A+%22There+must+be+some+kind+of+way+out+of+here%22&rft.au=Cegielski%2C+J+P&rft.aulast=Cegielski&rft.aufirst=J&rft.date=2010-05-15&rft.volume=50&rft.issue=&rft.spage=S195&rft.isbn=&rft.btitle=&rft.title=Clinical+Infectious+Diseases&rft.issn=10584838&rft_id=info:doi/10.1086%2F651491 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Mortality; Drug resistance; Tuberculosis; Drugs; Public health; Mycobacterium tuberculosis DO - http://dx.doi.org/10.1086/651491 ER - TY - JOUR T1 - Prevalence of transmitted drug resistance associated mutations and HIV-1 subtypes in new HIV-1 diagnoses. U.S.--2006 AN - 745932285; 13031964 AB - Objective: To determine the distribution of HIV-1 subtypes and the prevalence of transmitted drug resistance-associated mutations (TDRM) among persons newly diagnosed with HIV-1 infection in the United States. Methods: We used sequence data from Variant, Atypical, and Resistant HIV Surveillance (VARHS) collected from newly diagnosed persons in 10 states and 1 county health department in 2006. To evaluate TDRM, we used a mutation list for surveillance of TDRM appropriate for the primarily subtype B HIV epidemic in the United States. Results: Sequences were obtained from 2030 of 10 860 persons newly diagnosed with HIV in 11 surveillance areas. Mutations associated with transmitted drug resistance occurred in 292 (14.6%) persons; TDRM associated with a specific drug class occurred in 156 (7.8%) for non-nucleoside reverse transcriptase inhibitors, 111 (5.6%) for nucleoside reverse transcriptase inhibitors and 90 (4.5%) for protease inhibitors. There were no significant differences in prevalence of TDRM by demographic characteristic. The HIV-1 subtype B was the most prevalent subtype occurring in 1922 (96.2%) persons; subtype C (1.3%) was the most prevalent non-B subtype. Conclusion: We presented a clade B-optimized mutation list for evaluating surveillance of TDRM in the United States and analyzed the largest collection of sequence data obtained from individuals newly diagnosed with HIV. The prevalence of TDRM in persons newly diagnosed with HIV is higher than in previous U.S. studies; however, this is not necessarily a significant trend. Continued reporting of sequence data for public health purposes from all sources will improve representativeness and accuracy in analyzing trends in transmitted drug resistance and genetic diversity. JF - AIDS AU - Wheeler, W H AU - Ziebell, R A AU - Zabina, H AU - Pieniazek, D AU - Prejean, J AU - Bodnar, U R AU - Mahle, K C AU - Heneine, W AU - Johnson, JA AU - Hall, H I AD - Centers for Disease Control and Prevention, 1600 Clifton Road NE MS E47, Atlanta, GA 30333, USA, jprejean@cdc.gov Y1 - 2010/05/15/ PY - 2010 DA - 2010 May 15 SP - 1203 EP - 1212 VL - 24 IS - 8 SN - 0269-9370, 0269-9370 KW - Biotechnology and Bioengineering Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - Data processing KW - Epidemics KW - non-nucleoside reverse transcriptase inhibitors KW - Drug resistance KW - Proteinase inhibitors KW - Genetic diversity KW - Infection KW - Public health KW - Demography KW - Human immunodeficiency virus 1 KW - Mutation KW - nucleoside reverse transcriptase inhibitors KW - V 22360:AIDS and HIV KW - F 06910:Microorganisms & Parasites KW - W 30900:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745932285?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS&rft.atitle=Prevalence+of+transmitted+drug+resistance+associated+mutations+and+HIV-1+subtypes+in+new+HIV-1+diagnoses.+U.S.--2006&rft.au=Wheeler%2C+W+H%3BZiebell%2C+R+A%3BZabina%2C+H%3BPieniazek%2C+D%3BPrejean%2C+J%3BBodnar%2C+U+R%3BMahle%2C+K+C%3BHeneine%2C+W%3BJohnson%2C+JA%3BHall%2C+H+I&rft.aulast=Wheeler&rft.aufirst=W&rft.date=2010-05-15&rft.volume=24&rft.issue=8&rft.spage=1203&rft.isbn=&rft.btitle=&rft.title=AIDS&rft.issn=02699370&rft_id=info:doi/10.1097%2FQAD.0b013e3283388742 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - Demography; non-nucleoside reverse transcriptase inhibitors; Epidemics; Data processing; Drug resistance; Proteinase inhibitors; Genetic diversity; Infection; Mutation; nucleoside reverse transcriptase inhibitors; Public health; Human immunodeficiency virus 1 DO - http://dx.doi.org/10.1097/QAD.0b013e3283388742 ER - TY - JOUR T1 - Circumcision status and HIV infection among MSM: reanalysis of a Phase III HIV vaccine clinical trial AN - 745931836; 13031956 AB - Objective: Determine whether male circumcision would be effective in reducing HIV transmission among men who have sex with men (MSM). Design: Retrospective analysis of the VAXGen VAX004 HIV vaccine clinical trial data. Methods: Survival analysis was used to associate time to HIV infection with multiple predictors. Unprotected insertive and receptive anal sex predictors were highly correlated, thus separate models were run. Results: Four thousand eight hundred and eighty-nine participants were included in this reanalysis; 86.1% were circumcised. Three hundred and forty-two (7.0%) men became infected during the study; 87.4% were circumcised. Controlling for demographic characteristics and risk behaviors, in the model that included unprotected insertive anal sex, being uncircumcised was not associated with incident HIV infection [adjusted hazards ratio (AHR) = 0.97, confidence interval (CI) = 0.56-1.68]. Furthermore, while having unprotected insertive (AHR = 2.25, CI = 1.72-2.93) or receptive (AHR = 3.45, CI = 2.58-4.61) anal sex with an HIV-positive partner were associated with HIV infection, the associations between HIV incidence and the interaction between being uncircumcised and reporting unprotected insertive (AHR = 1.78, CI = 0.90-3.53) or receptive (AHR = 1.26, CI = 0.62-2.57) anal sex with an HIV-positive partner were not statistically significant. Of the study visits when a participant reported unprotected insertive anal sex with an HIV-positive partner, HIV infection among circumcised men was reported in 3.16% of the visits (80/2532) and among uncircumcised men in 3.93% of the visits (14/356) [relative risk (RR) = 0.80, CI = 0.46-1.39]. Conclusions: Among men who reported unprotected insertive anal sex with HIV-positive partners, being uncircumcised did not confer a statistically significant increase in HIV infection risk. Additional studies with more incident HIV infections or that include a larger proportion of uncircumcised men may provide a more definitive result. JF - AIDS AU - Gust, DA AU - Wiegand, R E AU - Kretsinger, K AU - Sansom, S AU - Kilmarx, PH AU - Bartholow, B N AU - Chen, R T AD - HIV Vaccine and Special Studies Team, Epidemiology Branch, Division of HIV/AIDS Prevention, CDC 1600 Clifton Rd. Mail-Stop E-45, Atlanta, GA 30333, USA, dgust@cdc.gov Y1 - 2010/05/15/ PY - 2010 DA - 2010 May 15 SP - 1135 EP - 1143 VL - 24 IS - 8 SN - 0269-9370, 0269-9370 KW - Risk Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - Risk assessment KW - vaccines KW - Acquired immune deficiency syndrome KW - anal sex KW - Data processing KW - disease transmission KW - homosexuality KW - Statistical analysis KW - Survival KW - clinical trials KW - Infection KW - Clinical trials KW - Models KW - Disease transmission KW - Demography KW - Human immunodeficiency virus KW - infection KW - Vaccines KW - survival KW - Sex KW - V 22360:AIDS and HIV KW - F 06905:Vaccines KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745931836?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS&rft.atitle=Circumcision+status+and+HIV+infection+among+MSM%3A+reanalysis+of+a+Phase+III+HIV+vaccine+clinical+trial&rft.au=Gust%2C+DA%3BWiegand%2C+R+E%3BKretsinger%2C+K%3BSansom%2C+S%3BKilmarx%2C+PH%3BBartholow%2C+B+N%3BChen%2C+R+T&rft.aulast=Gust&rft.aufirst=DA&rft.date=2010-05-15&rft.volume=24&rft.issue=8&rft.spage=1135&rft.isbn=&rft.btitle=&rft.title=AIDS&rft.issn=02699370&rft_id=info:doi/10.1097%2FQAD.0b013e328337b8bd LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2013-12-16 N1 - SubjectsTermNotLitGenreText - Demography; Risk assessment; Data processing; anal sex; Statistical analysis; Survival; Vaccines; Infection; Clinical trials; Disease transmission; Sex; Models; Acquired immune deficiency syndrome; vaccines; disease transmission; Human immunodeficiency virus; homosexuality; infection; survival; clinical trials DO - http://dx.doi.org/10.1097/QAD.0b013e328337b8bd ER - TY - JOUR T1 - Identification of potential vectors of and detection of antibodies against Rift Valley fever virus in livestock during interepizootic periods AN - 755143067; 13678489 AB - Objective--To evaluate the prevalence of Rift Valley fever virus (RVFV) antibodies in livestock and presence of competent mosquito vectors of RVFV during an interepizootic period (IEP) in Kenya. Animals--208 sheep and 84 goats ranging in age from 4 months to 15 years, from 2 breeding herds. Procedures--Blood specimens were collected from the sheep and goats during the 1999-2006 IEP in Rift Valley Province, and serum was harvested. Serum specimens were tested for IgG and IgM antibodies against RVFV by use of an ELISA. In addition, 7,134 mosquitoes were trapped in Naivasha, Nairobi, and Northeastern Province, and speciation was performed. Results--No animals were seropositive for IgM against RVFV. Of the animals born after the 1997-1998 epizootic, 18% (34/188) of sheep were seropositive for IgG against RVFV, compared with 3% (2/75) of goats. Seventy percent (8,144/11,678) of the mosquitoes collected were of the Culex subgenera; 18% (2,102/11,678) were Aedes spp. Conclusions and Clinical Relevance--Detection of IgG in the sera of sheep and goats born after the 1997-1998 epizootic and before the 2006 epizootic indicated that virus activity existed during the IEP. Detection of Aedes mosquitoes, which are competent vectors of RVFV, suggested that a cryptic vector-to-vertebrate cycle may exist during IEPs. JF - American Journal of Veterinary Research AU - Rostal, M K AU - Evans, AL AU - Sang, R AU - Gikundi, S AU - Wakhule, L AU - Munyua, P AU - Macharia, J AU - Feikin AU - Breiman, R F AU - Njenga, M K AD - Department of Veterinary Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 55108, USA, Knjenga@ke.cdc.gov Y1 - 2010/05// PY - 2010 DA - May 2010 SP - 522 EP - 526 VL - 71 IS - 5 SN - 0002-9645, 0002-9645 KW - Entomology Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Immunology Abstracts; Virology & AIDS Abstracts KW - Speciation KW - Aedes KW - Enzyme-linked immunosorbent assay KW - Kenya, Nairobi KW - Vectors KW - Epizootics KW - Rift Valley fever KW - Hosts KW - Livestock KW - Public health KW - Disease transmission KW - Culex KW - Antibodies KW - Breeding KW - Serum KW - Immunoglobulin G KW - Rift Valley fever virus KW - ELISA KW - Aquatic insects KW - Rift valleys KW - Immunoglobulin M KW - V 22410:Animal Diseases KW - Q1 08484:Species interactions: parasites and diseases KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - F 06910:Microorganisms & Parasites KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/755143067?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Veterinary+Research&rft.atitle=Identification+of+potential+vectors+of+and+detection+of+antibodies+against+Rift+Valley+fever+virus+in+livestock+during+interepizootic+periods&rft.au=Rostal%2C+M+K%3BEvans%2C+AL%3BSang%2C+R%3BGikundi%2C+S%3BWakhule%2C+L%3BMunyua%2C+P%3BMacharia%2C+J%3BFeikin%3BBreiman%2C+R+F%3BNjenga%2C+M+K&rft.aulast=Rostal&rft.aufirst=M&rft.date=2010-05-01&rft.volume=71&rft.issue=5&rft.spage=522&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Veterinary+Research&rft.issn=00029645&rft_id=info:doi/10.2460%2Fajvr.71.5.522 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-09-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Antibodies; Serum; ELISA; Hosts; Rift valleys; Aquatic insects; Disease transmission; Public health; Speciation; Enzyme-linked immunosorbent assay; Breeding; Immunoglobulin G; Vectors; Rift Valley fever; Epizootics; Immunoglobulin M; Livestock; Culex; Aedes; Rift Valley fever virus; Kenya, Nairobi DO - http://dx.doi.org/10.2460/ajvr.71.5.522 ER - TY - JOUR T1 - Evaluation of a Preventive Program to Reduce Sensitization at a Beryllium Metal, Oxide, and Alloy Production Plant AN - 746310291; 13196395 AB - Objective: We evaluated a workplace preventive program's effectiveness, which emphasized skin and respiratory protection, workplace cleanliness, and beryllium migration control in lowering beryllium sensitization. Methods: We compared sensitization prevalence and incidence rates for workers hired before and after the program using available cross sectional and longitudinal surveillance data. Results: Sensitization prevalence was 8.9% for the Pre-Program Group and 2.1% for the Program Group. The sensitization incidence rate was 3.7/1000 person-months for the Pre-Program Group and 1.7/1000 person-months for the Program Group. After making adjustments for potential selection and information bias, sensitization prevalence for the Pre-Program Group was 3.8 times higher (95% CI = 1.5 to 9.3) than the Program Group. The sensitization incidence rate ratio comparing the Pre-Program Group to the Program Group was 1.6 (95% CI = 0.8 to 3.6). Conclusions: This preventive program reduced the prevalence of but did not eliminate beryllium sensitization. JF - Journal of Occupational and Environmental Medicine AU - Bailey, R L AU - Thomas, CA AU - Deubner, D C AU - Kent AU - Kreiss, K AU - Schuler, C R AD - Field Studies Branch, Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, 1095 Willowdale Road, MS H2800, Morgantown, WV 26505, USA, RLBailey@cdc.gov Y1 - 2010/05// PY - 2010 DA - May 2010 SP - 505 EP - 512 VL - 52 IS - 5 SN - 1076-2752, 1076-2752 KW - Toxicology Abstracts KW - Metals KW - Workers KW - Data processing KW - Skin KW - Beryllium KW - oxides KW - alloys KW - Migration KW - X 24360:Metals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/746310291?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Evaluation+of+a+Preventive+Program+to+Reduce+Sensitization+at+a+Beryllium+Metal%2C+Oxide%2C+and+Alloy+Production+Plant&rft.au=Bailey%2C+R+L%3BThomas%2C+CA%3BDeubner%2C+D+C%3BKent%3BKreiss%2C+K%3BSchuler%2C+C+R&rft.aulast=Bailey&rft.aufirst=R&rft.date=2010-05-01&rft.volume=52&rft.issue=5&rft.spage=505&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e3181d6c338 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-07-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Workers; Metals; Skin; Data processing; Beryllium; oxides; alloys; Migration DO - http://dx.doi.org/10.1097/JOM.0b013e3181d6c338 ER - TY - JOUR T1 - Analysis of applied forces and electromyography of back and shoulders muscles when performing a simulated hand scaling task AN - 746306221; 12963068 AB - Hand scaling is a physically demanding task responsible for numerous overexertion injuries in underground mining. Scaling requires the miner to use a long pry bar to remove loose rock, reducing the likelihood of rock fall injuries. The experiments described in this article simulated "rib" scaling (scaling a mine wall) from an elevated bucket to examine force generation and electromyographic responses using two types of scaling bars (steel and fiberglass-reinforced aluminum) at five target heights ranging from floor level to 176 cm. ten male and six female subjects were tested in separate experiments. Peak and average force applied at the scaling bar tip and normalized electromyography (EMG) of the left and right pairs of the deltoid and erectores spinae muscles were obtained. Work height significantly affected peak prying force during scaling activities with highest force capacity at the lower levels. Bar type did not affect force generation. However, use of the lighter fiberglass bar required significantly more muscle activity to achieve the same force. Results of these studies suggest that miners scale points on the rock face that are below their knees, and reposition the bucket as often as necessary to do so. JF - Applied Ergonomics AU - Porter, William AU - Gallagher, Sean AU - Torma-Krajewski, Janet AD - Pittsburgh Research Laboratory, National Institute for Occupational Safety and Health, 626 Cochrans Mill Road, P.O. Box 18070, Pittsburgh, PA 15236, USA, wlporter@cdc.gov Y1 - 2010/05// PY - 2010 DA - May 2010 SP - 411 EP - 416 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 41 IS - 3 SN - 0003-6870, 0003-6870 KW - Health & Safety Science Abstracts KW - Injuries KW - Occupational safety KW - Muscles KW - Mines KW - working conditions KW - scaling KW - Fiberglass KW - Aluminum KW - Steel KW - Mining KW - Ergonomics KW - H 10000:Ergonomics/Human Factors UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/746306221?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+Ergonomics&rft.atitle=Analysis+of+applied+forces+and+electromyography+of+back+and+shoulders+muscles+when+performing+a+simulated+hand+scaling+task&rft.au=Porter%2C+William%3BGallagher%2C+Sean%3BTorma-Krajewski%2C+Janet&rft.aulast=Porter&rft.aufirst=William&rft.date=2010-05-01&rft.volume=41&rft.issue=3&rft.spage=411&rft.isbn=&rft.btitle=&rft.title=Applied+Ergonomics&rft.issn=00036870&rft_id=info:doi/10.1016%2Fj.apergo.2009.09.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-07-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Injuries; Fiberglass; Aluminum; Occupational safety; Muscles; Mining; Steel; Mines; Ergonomics; working conditions; scaling DO - http://dx.doi.org/10.1016/j.apergo.2009.09.004 ER - TY - JOUR T1 - Interlaboratory Comparison of Three Multiplexed Bead-Based Immunoassays for Measuring Serum Antibodies to Pneumococcal Polysaccharides AN - 745979114; 12845381 AB - Serotype-specific IgG, as quantified by a standardized WHO enzyme-linked immunosorbent assay (ELISA), is a serologic end point used to evaluate pneumococcal polysaccharide-based vaccine immunogenicity. Antibodies to each vaccine polysaccharide in licensed multivalent vaccines are quantified separately; this is laborious and consumes serum. We compared three bead-based immunoassays: a commercial assay (xMAP Pneumo14; Luminex) and two in-house assays (of the Health Protection Agency [HPA] and Centers for Disease Control and Prevention [CDC]), using the WHO-recommended standard reference and reference sera (n = 11) from vaccinated adults. Multiple comparisons of the IgG concentrations for seven conjugate vaccine serotypes were performed by sample (percent error), serotype (equivalency testing), and laboratory (concordance correlation coefficient [CCC]). When comparing concentrations by sample, bead-based immunoassays generally yielded higher antibody concentrations than the ELISA and had higher variability for serotypes 6B, 18C, and 23F. None of the three assays met the current WHO recommendation of 75% of sera falling within 40% of the assigned antibody concentrations for all seven serotypes. When compared by serotype, the CDC and HPA tests were equivalent for five of seven serotypes, whereas the Luminex assay was equivalent for four of seven serotypes. When overall mean IgG concentrations were compared by laboratory, a higher level of agreement (CCC close to 1) was found among bead-based immunoassays than between the assays and WHO assignments. When compared to WHO assignments, the HPA assay outperformed the other assays (r = 0.920; CCC = 0.894; coefficient of accuracy = 0.972). Additional testing with sera from immunogenicity studies should demonstrate the applicability of this methodology for vaccine evaluation. JF - Clinical and Vaccine Immunology AU - Whaley, Melissa J AU - Rose, Charles AU - Martinez, Joseph AU - Laher, Gouri AU - Sammons, Deborah L AU - Smith, Jerry P AU - Snawder, John E AU - Borrow, Ray AU - Biagini, Raymond E AU - Plikaytis, Brian AD - Meningitis and Vaccine Preventable Diseases Branch, Division of Bacterial Diseases, National Center of Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, Ssteiner@cdc.gov Y1 - 2010/05// PY - 2010 DA - May 2010 SP - 862 EP - 869 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 17 IS - 5 SN - 1556-679X, 1556-679X KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Disease control KW - Enzyme-linked immunosorbent assay KW - Immunogenicity KW - Immunoglobulin G KW - Polysaccharides KW - Serotypes KW - Vaccines KW - Streptococcus pneumoniae KW - J 02350:Immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745979114?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+and+Vaccine+Immunology&rft.atitle=Interlaboratory+Comparison+of+Three+Multiplexed+Bead-Based+Immunoassays+for+Measuring+Serum+Antibodies+to+Pneumococcal+Polysaccharides&rft.au=Whaley%2C+Melissa+J%3BRose%2C+Charles%3BMartinez%2C+Joseph%3BLaher%2C+Gouri%3BSammons%2C+Deborah+L%3BSmith%2C+Jerry+P%3BSnawder%2C+John+E%3BBorrow%2C+Ray%3BBiagini%2C+Raymond+E%3BPlikaytis%2C+Brian&rft.aulast=Whaley&rft.aufirst=Melissa&rft.date=2010-05-01&rft.volume=17&rft.issue=5&rft.spage=862&rft.isbn=&rft.btitle=&rft.title=Clinical+and+Vaccine+Immunology&rft.issn=1556679X&rft_id=info:doi/10.1128%2FCVI.00022-10 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Number of references - 18 N1 - Last updated - 2013-05-06 N1 - SubjectsTermNotLitGenreText - Enzyme-linked immunosorbent assay; Serotypes; Immunogenicity; Disease control; Immunoglobulin G; Vaccines; Polysaccharides; Streptococcus pneumoniae DO - http://dx.doi.org/10.1128/CVI.00022-10 ER - TY - JOUR T1 - Assessment of non-occupational exposure to polycyclic aromatic hydrocarbons through personal air sampling and urinary biomonitoring AN - 745726693; 13106015 AB - Non-occupational inhalation and ingestion exposure to polycyclic aromatic hydrocarbons (PAHs) has been studied in 8 non-smoking volunteers through personal air sampling and urinary biomonitoring. The study period was divided into 4 segments (2 days/segment), including weekdays with regular commute and weekends with limited traffic related exposures; each segment had a high or low PAH diet. Personal air samples were collected continuously from the subjects while at home, at work, and while commuting to and from work. All urine excretions were collected as individual samples during the study. In personal air samples, 28 PAHs were measured, and in urine samples 9 mono-hydroxylated metabolites (OH-PAHs) from 4 parent PAHs (naphthalene, fluorene, phenanthrene and pyrene) were measured. Naphthalene was found at higher concentrations in air samples collected at the subjects' residences, whereas PAHs with four or more aromatic rings were found at higher levels in samples taken while commuting. Urinary OH-PAH biomarker levels increased following reported high inhalation and/or dietary exposure. On days with a low PAH diet, the total amount of inhaled naphthalene during each 24-hour period was well correlated with the amount of excreted naphthols, as was, to a lesser extent, fluorene with its urinary metabolites. During days with a high dietary intake, only naphthalene was significantly correlated with its excreted metabolite. These findings suggest that this group of non-occupational subjects were exposed to naphthalene primarily through indoor air inhalation, and exposed to other PAHs such as pyrene mainly through ingestion. JF - Journal of Environmental Monitoring AU - Li, Z AU - Mulholland, JA AU - Romanoff, L C AU - Pittman, EN AU - Trinidad, DA AU - Lewin, MD AU - Sjoedin, A AD - Centers for Disease Control and Prevention, 4770 Buford Highway F-53, Atlanta, GA, 30341, USA, ZJLi@cdc.gov Y1 - 2010/05// PY - 2010 DA - May 2010 SP - 1110 EP - 1118 VL - 12 IS - 5 SN - 1464-0325, 1464-0325 KW - Toxicology Abstracts; Environment Abstracts; Pollution Abstracts KW - Inhalation KW - Metabolites KW - Pyrene KW - Dietary intake KW - pyrene KW - phenanthrene KW - Air sampling KW - biomonitoring KW - Sampling KW - Bioindicators KW - Diets KW - Environmental monitoring KW - Polycyclic aromatic hydrocarbons KW - fluorene KW - Commuting KW - Naphthalene KW - Ingestion KW - biomarkers KW - Traffic KW - Nutrient deficiency KW - Phenanthrene KW - traffic KW - Urine KW - polycyclic aromatic hydrocarbons KW - Excretion KW - Indoor environments KW - Aromatics KW - P 0000:AIR POLLUTION KW - X 24350:Industrial Chemicals KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745726693?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+Monitoring&rft.atitle=Assessment+of+non-occupational+exposure+to+polycyclic+aromatic+hydrocarbons+through+personal+air+sampling+and+urinary+biomonitoring&rft.au=Li%2C+Z%3BMulholland%2C+JA%3BRomanoff%2C+L+C%3BPittman%2C+EN%3BTrinidad%2C+DA%3BLewin%2C+MD%3BSjoedin%2C+A&rft.aulast=Li&rft.aufirst=Z&rft.date=2010-05-01&rft.volume=12&rft.issue=5&rft.spage=1110&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+Monitoring&rft.issn=14640325&rft_id=info:doi/10.1039%2Fc000689k LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2013-06-28 N1 - SubjectsTermNotLitGenreText - Environmental monitoring; Inhalation; fluorene; Polycyclic aromatic hydrocarbons; Naphthalene; Metabolites; Pyrene; Dietary intake; biomarkers; Traffic; Phenanthrene; Nutrient deficiency; Urine; biomonitoring; Excretion; Sampling; Aromatics; Diets; Bioindicators; Commuting; Ingestion; phenanthrene; pyrene; traffic; Air sampling; polycyclic aromatic hydrocarbons; Indoor environments DO - http://dx.doi.org/10.1039/c000689k ER - TY - JOUR T1 - Hospitalization of paediatric patients for methicillin-resistant Staphylococcus aureus skin and soft-tissue infection, 1998-2006 AN - 744697163; 12582012 AB - Hospital discharge reports have provided data for studies of methicillin-resistant Staphylococcus aureus (MRSA) skin and soft-tissue infection (SSTI) studies. This analysis determined the sensitivity and positive predictive value of International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) code combinations to calculate hospitalization incidence rates, representativeness of a set of three ICD-9-CM codes to define MRSA SSTI, and hospitalization incidence rate trends for paediatric MRSA SSTIs in Los Angeles County (LAC). Using 133 cases from 31 hospitals, we found that the set of three ICD-9-CM codes used to define laboratory-confirmed cases had one of the highest positive predictive values (49%). There was no difference in age and race between those categorized using three codes vs. other code combinations. A dramatic increase in paediatric MRSA SSTI cases occurred in LAC during 1998-2006. We conclude that this combination of codes may be used to determine the rise of MRSA SSTIs in paediatric populations. JF - Epidemiology and Infection AU - Sircar, K D AU - Bancroft, E AU - Nguyen, D M AU - Mascola, L AD - Los Angeles County, Department of Public Health, Los Angeles, California, USA, ddq0@cdc.gov Y1 - 2010/05// PY - 2010 DA - May 2010 SP - 677 EP - 682 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU UK VL - 138 IS - 5 SN - 0950-2688, 0950-2688 KW - Microbiology Abstracts B: Bacteriology KW - Age KW - Skin KW - Data processing KW - Classification KW - Pediatrics KW - Drug resistance KW - Staphylococcus aureus KW - Infection KW - Races KW - Hospitals KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/744697163?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Hospitalization+of+paediatric+patients+for+methicillin-resistant+Staphylococcus+aureus+skin+and+soft-tissue+infection%2C+1998-2006&rft.au=Sircar%2C+K+D%3BBancroft%2C+E%3BNguyen%2C+D+M%3BMascola%2C+L&rft.aulast=Sircar&rft.aufirst=K&rft.date=2010-05-01&rft.volume=138&rft.issue=5&rft.spage=677&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS095026880999121X LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-01 N1 - Number of references - 6 N1 - Last updated - 2013-07-26 N1 - SubjectsTermNotLitGenreText - Age; Data processing; Skin; Classification; Pediatrics; Drug resistance; Infection; Races; Hospitals; Staphylococcus aureus DO - http://dx.doi.org/10.1017/S095026880999121X ER - TY - JOUR T1 - Isolation of Rickettsia parkeri and Identification of a Novel Spotted Fever Group Rickettsia sp. from Gulf Coast Ticks (Amblyomma maculatum) in the United States AN - 744682975; 12676534 AB - Until recently, Amblyomma maculatum (the Gulf Coast tick) had garnered little attention compared to other species of human-biting ticks in the United States. A. maculatum is now recognized as the principal vector of Rickettsia parkeri, a pathogenic spotted fever group rickettsia (SFGR) that causes an eschar-associated illness in humans that resembles Rocky Mountain spotted fever. A novel SFGR, distinct from other recognized Rickettsia spp., has also been detected recently in A. maculatum specimens collected in several regions of the southeastern United States. In this study, 198 questing adult Gulf Coast ticks were collected at 4 locations in Florida and Mississippi; 28% of these ticks were infected with R. parkeri, and 2% of these were infected with a novel SFGR. Seventeen isolates of R. parkeri from individual specimens of A. maculatum were cultivated in Vero E6 cells; however, all attempts to isolate the novel SFGR were unsuccessful. Partial genetic characterization of the novel SFGR revealed identity with several recently described, incompletely characterized, and noncultivated SFGR, including QUOTATION_MARKCandidatus Rickettsia andeanaeQUOTATION_MARK and Rickettsia sp. Argentina detected in several species of Neotropical ticks from Argentina and Peru. These findings suggest that each of these QUOTATION_MARKnovelQUOTATION_MARK rickettsiae represent the same species. This study considerably expanded the number of low-passage, A. maculatum-derived isolates of R. parkeri and characterized a second, sympatric Rickettsia sp. found in Gulf Coast ticks. JF - Applied and Environmental Microbiology AU - Paddock, Christopher D AU - Fournier, Pierre-Edouard AU - Sumner, John W AU - Goddard, Jerome AU - Elshenawy, Yasmin AU - Metcalfe, Maureen G AU - Loftis, Amanda D AU - Varela-Stokes, Andrea AD - Infectious Diseases Pathology Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, cdp9@cdc.gov Y1 - 2010/05// PY - 2010 DA - May 2010 SP - 2689 EP - 2696 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 76 IS - 9 SN - 0099-2240, 0099-2240 KW - Entomology Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology KW - Amblyomma maculatum KW - Coasts KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - J 02400:Human Diseases KW - A 01390:Forestry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/744682975?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Isolation+of+Rickettsia+parkeri+and+Identification+of+a+Novel+Spotted+Fever+Group+Rickettsia+sp.+from+Gulf+Coast+Ticks+%28Amblyomma+maculatum%29+in+the+United+States&rft.au=Paddock%2C+Christopher+D%3BFournier%2C+Pierre-Edouard%3BSumner%2C+John+W%3BGoddard%2C+Jerome%3BElshenawy%2C+Yasmin%3BMetcalfe%2C+Maureen+G%3BLoftis%2C+Amanda+D%3BVarela-Stokes%2C+Andrea&rft.aulast=Paddock&rft.aufirst=Christopher&rft.date=2010-05-01&rft.volume=76&rft.issue=9&rft.spage=2689&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/10.1128%2FAEM.02737-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-01 N1 - Number of references - 1 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Coasts; Amblyomma maculatum DO - http://dx.doi.org/10.1128/AEM.02737-09 ER - TY - JOUR T1 - Associations of Job Strain and Occupation with Subclinical Atherosclerosis: The CARDIA Study AN - 744624366; 13043305 AB - Purpose - Although occupational factors have been associated with symptomatic ischemic heart disease, associations between job strain (low decision latitude and high psychological demands) and risk for subclinical atherosclerosis measured by coronary artery calcium (CAC) have not been assessed. Methods - CAC was measured in 3695 participants in the Coronary Artery Risk Development in Young Adults study in 2000 to 2001 and 2005 to2006. Job characteristics measured by the demand-control model (psychological demands and decision latitude) were assessed in 1987 to 1988 and in 1995 to 1996. Associations between non-zero CAC and previous job characteristics and occupation were assessed, adjusting for potential covariates. Results - Low decision latitude, high psychological demands, and job strain at either earlier examination were not associated with a positive CAC, nor were changes in the status of these job characteristics between 1987/1988 and 1995/1996. However, participants whose jobs were classified as managerial or professional in 1995/1996 were less likely to have a positive CAC than those in laborer occupations. Conclusions - Job strain measured at two earlier time points was not related to the presence of CAC at follow-up 5 to 18 years later. The association between earlier occupation and CAC may reflect socioeconomic differences or other occupational, industrial, or labor market characteristics. JF - Annals of Epidemiology AU - Greenlund, Kurt J AU - Kiefe, Catarina I AU - Giles, Wayne H AU - Liu, Kiang AD - Division of Adult and Community Health, Centers for Disease Control and Prevention, Atlanta, GA, keg9@cdc.gov Y1 - 2010/05// PY - 2010 DA - May 2010 SP - 323 EP - 331 PB - Elsevier Science, Box 882 New York NY 10159 USA VL - 20 IS - 5 SN - 1047-2797, 1047-2797 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Coronary Atherosclerosis KW - Occupation KW - Psychological Stress KW - Socioeconomic Factors KW - Calcium KW - employment KW - Psychology KW - Socioeconomics KW - latitude KW - young adults KW - heart diseases KW - Occupational health KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/744624366?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annals+of+Epidemiology&rft.atitle=Associations+of+Job+Strain+and+Occupation+with+Subclinical+Atherosclerosis%3A+The+CARDIA+Study&rft.au=Greenlund%2C+Kurt+J%3BKiefe%2C+Catarina+I%3BGiles%2C+Wayne+H%3BLiu%2C+Kiang&rft.aulast=Greenlund&rft.aufirst=Kurt&rft.date=2010-05-01&rft.volume=20&rft.issue=5&rft.spage=323&rft.isbn=&rft.btitle=&rft.title=Annals+of+Epidemiology&rft.issn=10472797&rft_id=info:doi/10.1016%2Fj.annepidem.2010.02.007 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - employment; Calcium; Psychology; Socioeconomics; latitude; young adults; heart diseases; Occupational health DO - http://dx.doi.org/10.1016/j.annepidem.2010.02.007 ER - TY - JOUR T1 - Transfusion-transmitted arboviruses AN - 744611375; 12855607 AB - There exists considerable risk for transfusion transmission of arboviruses due to short periods of asymptomatic viraemia in populations with variable and sometimes extremely high incidence of arboviral infections. Aside from West Nile virus, few arbovirus transfusion transmissions have been proven, mostly due to difficulties in ruling out vector-borne transmission in recipients with arbovirus disease. Nevertheless, arbovirus transfusion risk models and assessments of viraemia prevalence in blood donations indicate substantial transfusion transmission of dengue and Chikungunya viruses in epidemic areas. Many other arboviruses, several of which are importation risks in the Americas, Europe and Asia, also cause large outbreaks and threaten transfusion safety. Prevention largely depends on excluding donors from outbreak areas or implementation of highly sensitive nucleic acid amplification tests. Because of the increasing emergence of arboviral disease globally, it is prudent to prepare for both endemic and exotic arboviruses capable of producing large epidemics and subsequent transfusion transmission risk. JF - Vox Sanguinis AU - Petersen, L R AU - Busch, M P AD - 1Division of Vector-borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado, USA, lxp2@cdc.gov Y1 - 2010/05// PY - 2010 DA - May 2010 SP - 495 EP - 503 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 USA VL - 98 IS - 4 SN - 0042-9007, 0042-9007 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Virology & AIDS Abstracts; Risk Abstracts KW - arbovirus KW - transfusion KW - transmission KW - Human diseases KW - Viruses KW - Europe KW - Transfusion KW - Importation KW - Infection KW - Arbovirus KW - Models KW - Disease transmission KW - Public health KW - Endemic species KW - Dengue KW - blood donors KW - infection KW - prevention KW - Asia KW - Epidemics KW - outbreaks KW - Blood KW - nucleic acids KW - dengue KW - Viremia KW - West Nile virus KW - Nucleic acids KW - Q1 08484:Species interactions: parasites and diseases KW - R2 23060:Medical and environmental health KW - Q5 08524:Public health, medicines, dangerous organisms KW - V 22310:Genetics, Taxonomy & Structure UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/744611375?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vox+Sanguinis&rft.atitle=Transfusion-transmitted+arboviruses&rft.au=Petersen%2C+L+R%3BBusch%2C+M+P&rft.aulast=Petersen&rft.aufirst=L&rft.date=2010-05-01&rft.volume=98&rft.issue=4&rft.spage=495&rft.isbn=&rft.btitle=&rft.title=Vox+Sanguinis&rft.issn=00429007&rft_id=info:doi/10.1111%2Fj.1423-0410.2009.01286.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Number of references - 61 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Human diseases; Endemic species; Epidemics; Viruses; Nucleic acids; Public health; Disease transmission; Blood; nucleic acids; Dengue; Viremia; Infection; Importation; Transfusion; Models; blood donors; prevention; infection; dengue; outbreaks; transfusion; West Nile virus; Arbovirus; Europe; Asia DO - http://dx.doi.org/10.1111/j.1423-0410.2009.01286.x ER - TY - JOUR T1 - Carbon monoxide-related hospitalizations in the U.S.: evaluation of a web-based query system for public health surveillance. AN - 733937913; 20433037 AB - Carbon monoxide (CO) poisoning is preventable, yet it remains one of the most common causes of poisoning in the U.S. In the absence of a national data reporting system for CO-poisoning surveillance, the burden of CO-related hospitalizations is unknown. Our objective was to generate the first national estimates of CO-related hospitalizations and to evaluate the use of a Web-based query system for public health surveillance. The Healthcare Cost and Utilization Project's (HCUP's) 2005 Nationwide Inpatient Sample (NIS) data were used for CO-related hospitalization estimates. Data for confirmed, probable, and suspected cases were generated using the HCUPnet Web-based query system. We used data from 1993 through 2005 NIS to describe trends in CO-related hospitalizations. We used the Centers for Disease Control and Prevention's surveillance evaluation guidelines to evaluate the system. In 2005, there were 24,891 CO-related hospitalizations nationwide: 16.9% (n=4,216) were confirmed, 1.1% (n=279) were probable, and 81.9% (n=20,396) were suspected CO-poisoning cases. Of the confirmed cases (1.42/100,000 population), the highest hospitalization rates occurred among males, older adults (aged > or = 85 years), and Midwestern residents. CO-related hospitalization rates declined from 1993 through 2000 and plateaued from 2001 through 2005. The simplicity, acceptability, sensitivity, and representativeness of the HCUPnet surveillance system were excellent. However, HCUPnet showed limited flexibility and specificity. Nationwide, the burden of CO exposure resulting in hospitalization is substantial. HCUPnet is a useful surveillance tool that efficiently characterized CO-related hospitalizations for the first time. Public health practitioners can utilize this data source for state-level surveillance. JF - Public health reports (Washington, D.C. : 1974) AU - Iqbal, Shahed AU - Clower, Jacquelyn H AU - Boehmer, Tegan K AU - Yip, Fuyuen Y AU - Garbe, Paul AD - Epidemic Intelligence Service, Air Pollution and Respiratory Health Branch, National Center for Environmental Health, Division of Environmental Hazards and Health Effects, CDC, Chamblee, GA 30341, USA. SIqbal@cdc.gov PY - 2010 SP - 423 EP - 432 VL - 125 IS - 3 SN - 0033-3549, 0033-3549 KW - Abridged Index Medicus KW - Index Medicus KW - Sensitivity and Specificity KW - Reproducibility of Results KW - International Classification of Diseases KW - Humans KW - Infant, Newborn KW - Aged KW - Child KW - Child, Preschool KW - Infant KW - Aged, 80 and over KW - Adult KW - Middle Aged KW - Adolescent KW - United States -- epidemiology KW - Male KW - Female KW - Internet KW - Databases, Factual KW - Hospitalization -- statistics & numerical data KW - Carbon Monoxide Poisoning -- epidemiology KW - Information Storage and Retrieval KW - Population Surveillance -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733937913?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Public+health+reports+%28Washington%2C+D.C.+%3A+1974%29&rft.atitle=Carbon+monoxide-related+hospitalizations+in+the+U.S.%3A+evaluation+of+a+web-based+query+system+for+public+health+surveillance.&rft.au=Iqbal%2C+Shahed%3BClower%2C+Jacquelyn+H%3BBoehmer%2C+Tegan+K%3BYip%2C+Fuyuen+Y%3BGarbe%2C+Paul&rft.aulast=Iqbal&rft.aufirst=Shahed&rft.date=2010-05-01&rft.volume=125&rft.issue=3&rft.spage=423&rft.isbn=&rft.btitle=&rft.title=Public+health+reports+%28Washington%2C+D.C.+%3A+1974%29&rft.issn=00333549&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-05-26 N1 - Date created - 2010-05-03 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Toxicology. 2000 Apr 7;145(1):1-14 [10771127] Emerg Med J. 2002 Sep;19(5):386-90 [12204981] J Int Neuropsychol Soc. 2004 Jan;10(1):60-71 [14751008] MMWR Morb Mortal Wkly Rep. 1996 Jan 12;45(1):1-3 [8531914] J Clin Psychol. 1998 Aug;54(5):555-67 [9696105] J Emerg Med. 1998 Sep-Oct;16(5):695-8 [9752939] N Engl J Med. 1998 Nov 26;339(22):1603-8 [9828249] Curr Opin Pediatr. 1999 Jun;11(3):259-64 [10349107] Behav Cogn Neurosci Rev. 2006 Sep;5(3):141-55 [16891556] MMWR Morb Mortal Wkly Rep. 2007 Feb 9;56(5):93-6 [17287712] MMWR Recomm Rep. 2001 Jul 27;50(RR-13):1-35; quiz CE1-7 [18634202] MMWR Morb Mortal Wkly Rep. 2008 Aug 22;57(33):896-9 [18716581] N Engl J Med. 2009 Mar 19;360(12):1217-25 [19297574] N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Recreational exposure to microcystins during algal blooms in two California lakes. AN - 733183202; 19615396 AB - We conducted a study of recreational exposure to microcystins among 81 children and adults planning recreational activities on either of three California reservoirs, two with significant, ongoing blooms of toxin-producing cyanobacteria, including Microcystis aeruginosa (Bloom Lakes), and one without a toxin-producing algal bloom (Control Lake). We analyzed water samples for algal taxonomy, microcystin concentrations, and potential respiratory viruses (adenoviruses and enteroviruses). We measured microcystins in personal air samples, nasal swabs, and blood samples. We interviewed study participants for demographic and health symptoms information. We found highly variable microcystin concentrations in Bloom Lakes (500 microg/L); microcystin was not detected in the Control Lake. We did not detect adenoviruses or enteroviruses in any of the lakes. Low microcystin concentrations were found in personal air samples (<0.1 ng/m(3) [limit of detection]-2.89 ng/m(3)) and nasal swabs (<0.1 ng [limit of detection]-5 ng). Microcystin concentrations in the water-soluble fraction of all plasma samples were below the limit of detection (1.0 microg/L). Our findings indicate that recreational activities in water bodies that experience toxin-producing cyanobacterial blooms can generate aerosolized cyanotoxins, making inhalation a potential route of exposure. Future studies should include collecting nasal swabs to assess upper respiratory tract deposition of toxin-containing aerosols droplets. Published by Elsevier Ltd. JF - Toxicon : official journal of the International Society on Toxinology AU - Backer, Lorraine C AU - McNeel, Sandra V AU - Barber, Terry AU - Kirkpatrick, Barbara AU - Williams, Christopher AU - Irvin, Mitch AU - Zhou, Yue AU - Johnson, Trisha B AU - Nierenberg, Kate AU - Aubel, Mark AU - LePrell, Rebecca AU - Chapman, Andrew AU - Foss, Amanda AU - Corum, Susan AU - Hill, Vincent R AU - Kieszak, Stephanie M AU - Cheng, Yung-Sung AD - National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway NE, MS F-57, Chamblee, GA 30341, USA. lbacker@cdc.gov Y1 - 2010/05// PY - 2010 DA - May 2010 SP - 909 EP - 921 VL - 55 IS - 5 KW - Microcystins KW - 0 KW - Water Pollutants, Chemical KW - Index Medicus KW - California KW - Young Adult KW - Fresh Water -- chemistry KW - Humans KW - Environmental Exposure -- analysis KW - Adult KW - Aged KW - Middle Aged KW - Child KW - Adolescent KW - Water Microbiology KW - Male KW - Female KW - Environmental Monitoring -- methods KW - Microcystis -- metabolism KW - Recreation -- physiology KW - Water Pollutants, Chemical -- analysis KW - Water Pollutants, Chemical -- adverse effects KW - Microcystis -- isolation & purification KW - Microcystins -- adverse effects KW - Harmful Algal Bloom KW - Microcystis -- classification KW - Microcystins -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733183202?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicon+%3A+official+journal+of+the+International+Society+on+Toxinology&rft.atitle=Recreational+exposure+to+microcystins+during+algal+blooms+in+two+California+lakes.&rft.au=Backer%2C+Lorraine+C%3BMcNeel%2C+Sandra+V%3BBarber%2C+Terry%3BKirkpatrick%2C+Barbara%3BWilliams%2C+Christopher%3BIrvin%2C+Mitch%3BZhou%2C+Yue%3BJohnson%2C+Trisha+B%3BNierenberg%2C+Kate%3BAubel%2C+Mark%3BLePrell%2C+Rebecca%3BChapman%2C+Andrew%3BFoss%2C+Amanda%3BCorum%2C+Susan%3BHill%2C+Vincent+R%3BKieszak%2C+Stephanie+M%3BCheng%2C+Yung-Sung&rft.aulast=Backer&rft.aufirst=Lorraine&rft.date=2010-05-01&rft.volume=55&rft.issue=5&rft.spage=909&rft.isbn=&rft.btitle=&rft.title=Toxicon+%3A+official+journal+of+the+International+Society+on+Toxinology&rft.issn=1879-3150&rft_id=info:doi/10.1016%2Fj.toxicon.2009.07.006 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-06-08 N1 - Date created - 2010-03-12 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.toxicon.2009.07.006 ER - TY - JOUR T1 - Relationship of work injury severity to family member hospitalization AN - 1017965311; 16691679 AB - Background Working while under stress due to a family health event may result in injuries of greater severity. Work leave might mitigate such consequences. Data and Methods Workers' compensation data for 33,817 injured workers and inpatient medical data for 76,077 members of their families were extracted from the 2002-2005 Thomson Reuters Medstat MarketScan Health and Productivity Management (HPM) and Commercial Claims and Encounter (CCE) datasets. Using a probit model, the impact of family hospitalization on the probability that a subsequent injury would be severe (above average indemnity costs) was estimated, adjusting for age, sex, hourly versus salaried status, industry sector, state, and family size. Results Family hospitalization within 15 days before injury increased the likelihood that the injury would be severe (from 12.5% to 21.5%) and was associated with 40% higher indemnity costs and 50% higher medical costs. Hospitalizations over 30 days before injury had no impact. Conclusion The observed higher severity of work injuries following family hospitalizations suggests additional analyses may find higher injury rates as well, and that timely family leaves might help prevent severe workplace injuries. Am. J. Ind. Med. 53:506-513, 2010. ? 2010 Wiley-Liss, Inc. JF - American Journal of Industrial Medicine AU - Asfaw, Abay G AU - Bushnell, P Timothy AU - Ray, Tapas K AD - Centers for Disease Control and Prevention (CDC), National Institute for Occupational Safety and Health (NIOSH), Office of the Director, Washington, District of Columbia, hqp0@cdc.gov Y1 - 2010/05// PY - 2010 DA - May 2010 SP - 506 EP - 513 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 53 IS - 5 SN - 1097-0274, 1097-0274 KW - Health & Safety Science Abstracts KW - workers' compensation KW - Age KW - Injuries KW - Stress KW - family size KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1017965311?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Relationship+of+work+injury+severity+to+family+member+hospitalization&rft.au=Asfaw%2C+Abay+G%3BBushnell%2C+P+Timothy%3BRay%2C+Tapas+K&rft.aulast=Asfaw&rft.aufirst=Abay&rft.date=2010-05-01&rft.volume=53&rft.issue=5&rft.spage=506&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=10970274&rft_id=info:doi/10.1002%2Fajim.20804 L2 - http://onlinelibrary.wiley.com/doi/10.1002/ajim.20804/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2013-06-28 N1 - SubjectsTermNotLitGenreText - workers' compensation; Age; Injuries; Stress; family size DO - http://dx.doi.org/10.1002/ajim.20804 ER - TY - CPAPER T1 - Simultaneous Administration Among Females of HPV4 Vaccine and Other Vaccines Recommended for Adolescents-- Immunization Information System Sentinel Sites, United States, 2008-2009 T2 - 44th National Immunization Conference (NIC 2010) AN - 754216132; 5751713 JF - 44th National Immunization Conference (NIC 2010) AU - Cullen, Karen AU - Bartlett, Diana AU - Curtis, C Y1 - 2010/04/19/ PY - 2010 DA - 2010 Apr 19 KW - USA KW - Vaccines KW - Information systems KW - Immunization KW - Disease control KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754216132?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=44th+National+Immunization+Conference+%28NIC+2010%29&rft.atitle=Simultaneous+Administration+Among+Females+of+HPV4+Vaccine+and+Other+Vaccines+Recommended+for+Adolescents--+Immunization+Information+System+Sentinel+Sites%2C+United+States%2C+2008-2009&rft.au=Cullen%2C+Karen%3BBartlett%2C+Diana%3BCurtis%2C+C&rft.aulast=Cullen&rft.aufirst=Karen&rft.date=2010-04-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=44th+National+Immunization+Conference+%28NIC+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://cdc.confex.com/cdc/nic2010/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - Assessing Variability Among IIS Vaccine Forecasting Algorithms T2 - 44th National Immunization Conference (NIC 2010) AN - 754216031; 5751682 JF - 44th National Immunization Conference (NIC 2010) AU - Kelly, Janet AU - Bryant, Amanda AU - Pabst, Laura Y1 - 2010/04/19/ PY - 2010 DA - 2010 Apr 19 KW - Vaccines KW - Algorithms KW - Prediction KW - Disease control KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754216031?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=44th+National+Immunization+Conference+%28NIC+2010%29&rft.atitle=Assessing+Variability+Among+IIS+Vaccine+Forecasting+Algorithms&rft.au=Kelly%2C+Janet%3BBryant%2C+Amanda%3BPabst%2C+Laura&rft.aulast=Kelly&rft.aufirst=Janet&rft.date=2010-04-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=44th+National+Immunization+Conference+%28NIC+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://cdc.confex.com/cdc/nic2010/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - Understanding IIS Performance and Dynamics: A Different Way of Looking at IIS Data T2 - 44th National Immunization Conference (NIC 2010) AN - 754214982; 5751654 JF - 44th National Immunization Conference (NIC 2010) AU - Heboyan, Vahe AU - Kelly, Janet AU - Rasulnia, Bobby Y1 - 2010/04/19/ PY - 2010 DA - 2010 Apr 19 KW - Data processing KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754214982?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=44th+National+Immunization+Conference+%28NIC+2010%29&rft.atitle=Understanding+IIS+Performance+and+Dynamics%3A+A+Different+Way+of+Looking+at+IIS+Data&rft.au=Heboyan%2C+Vahe%3BKelly%2C+Janet%3BRasulnia%2C+Bobby&rft.aulast=Heboyan&rft.aufirst=Vahe&rft.date=2010-04-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=44th+National+Immunization+Conference+%28NIC+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://cdc.confex.com/cdc/nic2010/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - Assessing Human Papillomavirus (HPV) Vaccination Practices Among Providers in IHS, Tribal and Urban Indian Health Facilities T2 - 44th National Immunization Conference (NIC 2010) AN - 754214493; 5751541 JF - 44th National Immunization Conference (NIC 2010) AU - Jim, Cheyenne AU - Wai Lee, Jennifer AU - Groom, Amy AU - Espey, David AU - Saraiya, Mona AU - Holve, Steve AU - Bullock, Ann AU - Howe, Jean AU - Thierry, Judith Y1 - 2010/04/19/ PY - 2010 DA - 2010 Apr 19 KW - Vaccination KW - Public health KW - Human papillomavirus KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754214493?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=44th+National+Immunization+Conference+%28NIC+2010%29&rft.atitle=Assessing+Human+Papillomavirus+%28HPV%29+Vaccination+Practices+Among+Providers+in+IHS%2C+Tribal+and+Urban+Indian+Health+Facilities&rft.au=Jim%2C+Cheyenne%3BWai+Lee%2C+Jennifer%3BGroom%2C+Amy%3BEspey%2C+David%3BSaraiya%2C+Mona%3BHolve%2C+Steve%3BBullock%2C+Ann%3BHowe%2C+Jean%3BThierry%2C+Judith&rft.aulast=Jim&rft.aufirst=Cheyenne&rft.date=2010-04-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=44th+National+Immunization+Conference+%28NIC+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://cdc.confex.com/cdc/nic2010/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - Coverage with Tetanus Toxoid-Containing Vaccination (TTCV), Including Tetanus, Diphtheria, Acellular Pertussis (Tdap) Vaccine, Among U.S. Adults T2 - 44th National Immunization Conference (NIC 2010) AN - 754208735; 5751660 JF - 44th National Immunization Conference (NIC 2010) AU - Miller, Brady AU - Kretsinger, Katrina AU - Ahmed, Faruque AU - Lu, Pengjun AU - Euler, Gary Y1 - 2010/04/19/ PY - 2010 DA - 2010 Apr 19 KW - USA KW - Vaccines KW - Tetanus KW - Vaccination KW - Pertussis KW - Diphtheria KW - Disease control KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754208735?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=44th+National+Immunization+Conference+%28NIC+2010%29&rft.atitle=Coverage+with+Tetanus+Toxoid-Containing+Vaccination+%28TTCV%29%2C+Including+Tetanus%2C+Diphtheria%2C+Acellular+Pertussis+%28Tdap%29+Vaccine%2C+Among+U.S.+Adults&rft.au=Miller%2C+Brady%3BKretsinger%2C+Katrina%3BAhmed%2C+Faruque%3BLu%2C+Pengjun%3BEuler%2C+Gary&rft.aulast=Miller&rft.aufirst=Brady&rft.date=2010-04-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=44th+National+Immunization+Conference+%28NIC+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://cdc.confex.com/cdc/nic2010/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - Achieving Full Vaccination with Influenza Vaccine Among Children Aged 6-59 Months - Immunization Information System (IIS) Sentinel Sites, 2007-08 Influenza Season T2 - 44th National Immunization Conference (NIC 2010) AN - 754207658; 5751521 JF - 44th National Immunization Conference (NIC 2010) AU - Pabst, Laura AU - Fiore, Anthony AU - Cullen, Karen Y1 - 2010/04/19/ PY - 2010 DA - 2010 Apr 19 KW - Influenza KW - Vaccines KW - Information systems KW - Children KW - Immunization KW - Vaccination KW - Disease control KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754207658?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=44th+National+Immunization+Conference+%28NIC+2010%29&rft.atitle=Achieving+Full+Vaccination+with+Influenza+Vaccine+Among+Children+Aged+6-59+Months+-+Immunization+Information+System+%28IIS%29+Sentinel+Sites%2C+2007-08+Influenza+Season&rft.au=Pabst%2C+Laura%3BFiore%2C+Anthony%3BCullen%2C+Karen&rft.aulast=Pabst&rft.aufirst=Laura&rft.date=2010-04-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=44th+National+Immunization+Conference+%28NIC+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://cdc.confex.com/cdc/nic2010/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - 2009 Pandemic Influenza A (H1N1) Virus Infection Among Pregnant Women in the United States, April-August, 2009 T2 - 44th National Immunization Conference (NIC 2010) AN - 754207655; 5751441 JF - 44th National Immunization Conference (NIC 2010) AU - Siston, Alicia AU - Rasmussen, Sonja AU - Honein, Margaret AU - Seib, Katherine AU - Jamieson, Denise Y1 - 2010/04/19/ PY - 2010 DA - 2010 Apr 19 KW - USA KW - Infection KW - Pregnancy KW - Influenza KW - Pandemics KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754207655?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=44th+National+Immunization+Conference+%28NIC+2010%29&rft.atitle=2009+Pandemic+Influenza+A+%28H1N1%29+Virus+Infection+Among+Pregnant+Women+in+the+United+States%2C+April-August%2C+2009&rft.au=Siston%2C+Alicia%3BRasmussen%2C+Sonja%3BHonein%2C+Margaret%3BSeib%2C+Katherine%3BJamieson%2C+Denise&rft.aulast=Siston&rft.aufirst=Alicia&rft.date=2010-04-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=44th+National+Immunization+Conference+%28NIC+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://cdc.confex.com/cdc/nic2010/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - Seasonal and Influenza A (H1N1) 2009 Monovalent [2009 H1N1] Vaccine Coverage Among Healthcare Personnel in the Indian Health Service T2 - 44th National Immunization Conference (NIC 2010) AN - 754207384; 5751542 JF - 44th National Immunization Conference (NIC 2010) AU - Groom, Amy AU - Jim, Cheyenne AU - Peterson, Cheryl Y1 - 2010/04/19/ PY - 2010 DA - 2010 Apr 19 KW - Seasonal variations KW - Vaccines KW - Health care KW - Sulfur dioxide KW - Influenza KW - Influenza A KW - Personnel KW - Disease control KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754207384?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=44th+National+Immunization+Conference+%28NIC+2010%29&rft.atitle=Seasonal+and+Influenza+A+%28H1N1%29+2009+Monovalent+%5B2009+H1N1%5D+Vaccine+Coverage+Among+Healthcare+Personnel+in+the+Indian+Health+Service&rft.au=Groom%2C+Amy%3BJim%2C+Cheyenne%3BPeterson%2C+Cheryl&rft.aulast=Groom&rft.aufirst=Amy&rft.date=2010-04-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=44th+National+Immunization+Conference+%28NIC+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://cdc.confex.com/cdc/nic2010/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - Who Got H1N1 Vaccine? Findings From the U.S. 2009-2010 Influenza Vaccination Surveillance Systems T2 - 44th National Immunization Conference (NIC 2010) AN - 754206563; 5751730 JF - 44th National Immunization Conference (NIC 2010) AU - Singleton, James Y1 - 2010/04/19/ PY - 2010 DA - 2010 Apr 19 KW - USA KW - Vaccines KW - Influenza KW - Vaccination KW - Disease control KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754206563?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=44th+National+Immunization+Conference+%28NIC+2010%29&rft.atitle=Who+Got+H1N1+Vaccine%3F+Findings+From+the+U.S.+2009-2010+Influenza+Vaccination+Surveillance+Systems&rft.au=Singleton%2C+James&rft.aulast=Singleton&rft.aufirst=James&rft.date=2010-04-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=44th+National+Immunization+Conference+%28NIC+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://cdc.confex.com/cdc/nic2010/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - Immunization Funding T2 - 44th National Immunization Conference (NIC 2010) AN - 754206168; 5751663 JF - 44th National Immunization Conference (NIC 2010) AU - Rodewald, Lance Y1 - 2010/04/19/ PY - 2010 DA - 2010 Apr 19 KW - Immunization KW - Financing KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754206168?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=44th+National+Immunization+Conference+%28NIC+2010%29&rft.atitle=Immunization+Funding&rft.au=Rodewald%2C+Lance&rft.aulast=Rodewald&rft.aufirst=Lance&rft.date=2010-04-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=44th+National+Immunization+Conference+%28NIC+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://cdc.confex.com/cdc/nic2010/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - The IHS/ASIIS Immunization Interface: Building Data Exchange through Communication and Collaboration T2 - 44th National Immunization Conference (NIC 2010) AN - 754205242; 5751598 JF - 44th National Immunization Conference (NIC 2010) AU - Town, Cecile AU - Ruiz, Michelle AU - Rasmussen, Lisa AU - Groom, Amy AU - Hamstra, Scott AU - Parker, John Y1 - 2010/04/19/ PY - 2010 DA - 2010 Apr 19 KW - Communication KW - Immunization KW - Data processing KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754205242?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=44th+National+Immunization+Conference+%28NIC+2010%29&rft.atitle=The+IHS%2FASIIS+Immunization+Interface%3A+Building+Data+Exchange+through+Communication+and+Collaboration&rft.au=Town%2C+Cecile%3BRuiz%2C+Michelle%3BRasmussen%2C+Lisa%3BGroom%2C+Amy%3BHamstra%2C+Scott%3BParker%2C+John&rft.aulast=Town&rft.aufirst=Cecile&rft.date=2010-04-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=44th+National+Immunization+Conference+%28NIC+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://cdc.confex.com/cdc/nic2010/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - Using Surveillance Indicators for Vaccine-Preventable Diseases (VPDs): National Notifiable Diseases Surveillance System (NNDSS), 2000-2009 T2 - 44th National Immunization Conference (NIC 2010) AN - 754205064; 5751632 JF - 44th National Immunization Conference (NIC 2010) AU - Roush, Sandra AU - Baldy, Linda AU - Redd, Susan AU - Barskey, Al Y1 - 2010/04/19/ PY - 2010 DA - 2010 Apr 19 KW - Vaccines KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754205064?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=44th+National+Immunization+Conference+%28NIC+2010%29&rft.atitle=Using+Surveillance+Indicators+for+Vaccine-Preventable+Diseases+%28VPDs%29%3A+National+Notifiable+Diseases+Surveillance+System+%28NNDSS%29%2C+2000-2009&rft.au=Roush%2C+Sandra%3BBaldy%2C+Linda%3BRedd%2C+Susan%3BBarskey%2C+Al&rft.aulast=Roush&rft.aufirst=Sandra&rft.date=2010-04-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=44th+National+Immunization+Conference+%28NIC+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://cdc.confex.com/cdc/nic2010/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - Use of An Electronic Health Record System to Guide 2009 Pandemic Influenza A (H1N1) Response in the Indian Health Service T2 - 44th National Immunization Conference (NIC 2010) AN - 754202755; 5751440 JF - 44th National Immunization Conference (NIC 2010) AU - Groom, Amy AU - Redd, John AU - Jim, Cheyenne AU - Cullen, Theresa AU - Layne, Larry AU - Cheek, James Y1 - 2010/04/19/ PY - 2010 DA - 2010 Apr 19 KW - Influenza KW - Influenza A KW - Pandemics KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754202755?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=44th+National+Immunization+Conference+%28NIC+2010%29&rft.atitle=Use+of+An+Electronic+Health+Record+System+to+Guide+2009+Pandemic+Influenza+A+%28H1N1%29+Response+in+the+Indian+Health+Service&rft.au=Groom%2C+Amy%3BRedd%2C+John%3BJim%2C+Cheyenne%3BCullen%2C+Theresa%3BLayne%2C+Larry%3BCheek%2C+James&rft.aulast=Groom&rft.aufirst=Amy&rft.date=2010-04-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=44th+National+Immunization+Conference+%28NIC+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://cdc.confex.com/cdc/nic2010/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - Use of New Media and Risk Commmunication to Address Influenza Vaccine Hesitancy T2 - 44th National Immunization Conference (NIC 2010) AN - 754197990; 5751646 JF - 44th National Immunization Conference (NIC 2010) AU - Cory, Janine Y1 - 2010/04/19/ PY - 2010 DA - 2010 Apr 19 KW - Vaccines KW - Influenza KW - Disease control KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754197990?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=44th+National+Immunization+Conference+%28NIC+2010%29&rft.atitle=Use+of+New+Media+and+Risk+Commmunication+to+Address+Influenza+Vaccine+Hesitancy&rft.au=Cory%2C+Janine&rft.aulast=Cory&rft.aufirst=Janine&rft.date=2010-04-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=44th+National+Immunization+Conference+%28NIC+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://cdc.confex.com/cdc/nic2010/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - Evolution of Pertussis Diagnostic Testing in the U.S.: 1990-2008 T2 - 44th National Immunization Conference (NIC 2010) AN - 754197925; 5751734 JF - 44th National Immunization Conference (NIC 2010) AU - Faulkner, Amanda AU - Skoff, Tami AU - Mitchell, Christine AU - Clark, Thomas AU - Martin, Stacey Y1 - 2010/04/19/ PY - 2010 DA - 2010 Apr 19 KW - USA KW - Pertussis KW - Evolution KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754197925?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=44th+National+Immunization+Conference+%28NIC+2010%29&rft.atitle=Evolution+of+Pertussis+Diagnostic+Testing+in+the+U.S.%3A+1990-2008&rft.au=Faulkner%2C+Amanda%3BSkoff%2C+Tami%3BMitchell%2C+Christine%3BClark%2C+Thomas%3BMartin%2C+Stacey&rft.aulast=Faulkner&rft.aufirst=Amanda&rft.date=2010-04-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=44th+National+Immunization+Conference+%28NIC+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://cdc.confex.com/cdc/nic2010/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - The Section 317 American Recovery and Reinvestment Act Project: Delivering Science and Program for Public Health T2 - 44th National Immunization Conference (NIC 2010) AN - 754197763; 5751714 JF - 44th National Immunization Conference (NIC 2010) AU - Bell, Beth Y1 - 2010/04/19/ PY - 2010 DA - 2010 Apr 19 KW - Public health KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754197763?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=44th+National+Immunization+Conference+%28NIC+2010%29&rft.atitle=The+Section+317+American+Recovery+and+Reinvestment+Act+Project%3A+Delivering+Science+and+Program+for+Public+Health&rft.au=Bell%2C+Beth&rft.aulast=Bell&rft.aufirst=Beth&rft.date=2010-04-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=44th+National+Immunization+Conference+%28NIC+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://cdc.confex.com/cdc/nic2010/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - Trends in Hepatitis B (HepB) Birth Dose Vaccination Coverage by Annual Birth Cohorts, 1999-2007, National Immunization Survey (NIS) T2 - 44th National Immunization Conference (NIC 2010) AN - 754197676; 5751619 JF - 44th National Immunization Conference (NIC 2010) AU - Zhao, Zhen AU - Murphy, Trudy AU - Jacques-Carroll, Lisa Y1 - 2010/04/19/ PY - 2010 DA - 2010 Apr 19 KW - Immunization KW - Hepatitis B KW - Vaccination KW - Parturition KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754197676?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=44th+National+Immunization+Conference+%28NIC+2010%29&rft.atitle=Trends+in+Hepatitis+B+%28HepB%29+Birth+Dose+Vaccination+Coverage+by+Annual+Birth+Cohorts%2C+1999-2007%2C+National+Immunization+Survey+%28NIS%29&rft.au=Zhao%2C+Zhen%3BMurphy%2C+Trudy%3BJacques-Carroll%2C+Lisa&rft.aulast=Zhao&rft.aufirst=Zhen&rft.date=2010-04-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=44th+National+Immunization+Conference+%28NIC+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://cdc.confex.com/cdc/nic2010/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - Correlates of Seasonal Influenza Vaccine Uptake by Women During Pregnancy: Evidence From the Pregnancy Risk Assessment Monitoring System (PRAMS) T2 - 44th National Immunization Conference (NIC 2010) AN - 754196959; 5751498 JF - 44th National Immunization Conference (NIC 2010) AU - Ahluwalia, Indu AU - Jamieson, Denise AU - Rasmussen, Sonja AU - D'Angelo, Denise AU - Goodman, David AU - Hoban, Carol AU - Kim, Hanna AU - Cain, Rachel Y1 - 2010/04/19/ PY - 2010 DA - 2010 Apr 19 KW - Pregnancy KW - Seasonal variations KW - Risk assessment KW - Vaccines KW - Sulfur dioxide KW - Influenza KW - Monitoring systems KW - Disease control KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754196959?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=44th+National+Immunization+Conference+%28NIC+2010%29&rft.atitle=Correlates+of+Seasonal+Influenza+Vaccine+Uptake+by+Women+During+Pregnancy%3A+Evidence+From+the+Pregnancy+Risk+Assessment+Monitoring+System+%28PRAMS%29&rft.au=Ahluwalia%2C+Indu%3BJamieson%2C+Denise%3BRasmussen%2C+Sonja%3BD%27Angelo%2C+Denise%3BGoodman%2C+David%3BHoban%2C+Carol%3BKim%2C+Hanna%3BCain%2C+Rachel&rft.aulast=Ahluwalia&rft.aufirst=Indu&rft.date=2010-04-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=44th+National+Immunization+Conference+%28NIC+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://cdc.confex.com/cdc/nic2010/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - Mumps: 2010 Perspective T2 - 44th National Immunization Conference (NIC 2010) AN - 754192826; 5751432 JF - 44th National Immunization Conference (NIC 2010) AU - Gallagher, Kathleen Y1 - 2010/04/19/ PY - 2010 DA - 2010 Apr 19 KW - Mumps KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754192826?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=44th+National+Immunization+Conference+%28NIC+2010%29&rft.atitle=Mumps%3A+2010+Perspective&rft.au=Gallagher%2C+Kathleen&rft.aulast=Gallagher&rft.aufirst=Kathleen&rft.date=2010-04-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=44th+National+Immunization+Conference+%28NIC+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://cdc.confex.com/cdc/nic2010/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - The Impact of MMRV Vaccine Availability On the Coverage with MMR- and Varicella-Containing Vaccines Among Young Children, National Immunization Survey, 2005-2008 T2 - 44th National Immunization Conference (NIC 2010) AN - 754192610; 5751554 JF - 44th National Immunization Conference (NIC 2010) AU - Zhao, Zhen AU - Marin, Mona AU - Singleton, James Y1 - 2010/04/19/ PY - 2010 DA - 2010 Apr 19 KW - Vaccines KW - Children KW - Immunization KW - Disease control KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754192610?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=44th+National+Immunization+Conference+%28NIC+2010%29&rft.atitle=The+Impact+of+MMRV+Vaccine+Availability+On+the+Coverage+with+MMR-+and+Varicella-Containing+Vaccines+Among+Young+Children%2C+National+Immunization+Survey%2C+2005-2008&rft.au=Zhao%2C+Zhen%3BMarin%2C+Mona%3BSingleton%2C+James&rft.aulast=Zhao&rft.aufirst=Zhen&rft.date=2010-04-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=44th+National+Immunization+Conference+%28NIC+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://cdc.confex.com/cdc/nic2010/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - Lessons Learned From VTrckS Provider Order Pilot (VPOP) and Applied to VTrckS Development T2 - 44th National Immunization Conference (NIC 2010) AN - 754188860; 5751740 JF - 44th National Immunization Conference (NIC 2010) AU - Prescott, Brad Y1 - 2010/04/19/ PY - 2010 DA - 2010 Apr 19 KW - Development KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754188860?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=44th+National+Immunization+Conference+%28NIC+2010%29&rft.atitle=Lessons+Learned+From+VTrckS+Provider+Order+Pilot+%28VPOP%29+and+Applied+to+VTrckS+Development&rft.au=Prescott%2C+Brad&rft.aulast=Prescott&rft.aufirst=Brad&rft.date=2010-04-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=44th+National+Immunization+Conference+%28NIC+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://cdc.confex.com/cdc/nic2010/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - JOUR T1 - Concomitant administration of recombinant PsaA and PCV7 reduces Streptococcus pneumoniae serotype 19A colonization in a murine model AN - 744616126; 12981516 AB - A murine colonization model was used to determine the effect of co-administering 7-valent polysaccharide-protein conjugate vaccine and pneumococcal surface adhesin A. Mice were challenged intranasally with either PCV7 serotypes, 4 or 14, or a non-PCV7 serotype, 19A. Post-challenge samples were evaluated for IgG antibody levels, opsonophagocytic activity, and nasopharyngeal colonization. No interference was observed between immune responses from the concomitant and individual immunizations. Concomitant immunizations reduced carriage for tested serotypes; largest reduction was observed for 19A. From these mouse studies, co-administering pneumococcal antigens appear to expand coverage and reduce colonization against a non-PCV7 serotype without inhibiting immunogenicity to other serotypes. JF - Vaccine AU - Whaley, Melissa J AU - Sampson, Jacquelyn S AU - Johnson, Scott E AU - Rajam, Gowrisankar AU - Stinson-Parks, Annie AU - Holder, Patricia AU - Mauro, Erica AU - Romero-Steiner, Sandra AU - Carlone, George M AU - Ades, Edwin W AD - Division of Bacterial Diseases, Center of Disease Control and Prevention, 1600 Clifton Rd NE, MS G-05, Atlanta, GA 30333, United States, mwhaley@cdc.gov Y1 - 2010/04/19/ PY - 2010 DA - 2010 Apr 19 SP - 3071 EP - 3075 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 28 IS - 18 SN - 0264-410X, 0264-410X KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Adhesins KW - Streptococcus pneumoniae KW - Serotypes KW - F 06905:Vaccines KW - J 02350:Immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/744616126?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Concomitant+administration+of+recombinant+PsaA+and+PCV7+reduces+Streptococcus+pneumoniae+serotype+19A+colonization+in+a+murine+model&rft.au=Whaley%2C+Melissa+J%3BSampson%2C+Jacquelyn+S%3BJohnson%2C+Scott+E%3BRajam%2C+Gowrisankar%3BStinson-Parks%2C+Annie%3BHolder%2C+Patricia%3BMauro%2C+Erica%3BRomero-Steiner%2C+Sandra%3BCarlone%2C+George+M%3BAdes%2C+Edwin+W&rft.aulast=Whaley&rft.aufirst=Melissa&rft.date=2010-04-19&rft.volume=28&rft.issue=18&rft.spage=3071&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/10.1016%2Fj.vaccine.2010.02.086 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Serotypes; Streptococcus pneumoniae DO - http://dx.doi.org/10.1016/j.vaccine.2010.02.086 ER - TY - CPAPER T1 - Large Scale Built Environment Impact on US Obesity Epidemic-A Multilevel Approach T2 - 2010 Annual Meeting of the Association of American Geographers (AAG 2010) AN - 839618536; 5886012 JF - 2010 Annual Meeting of the Association of American Geographers (AAG 2010) AU - Zhang, Xingyou AU - Holt, James AU - Yang, Jiawen AU - French, Steven Y1 - 2010/04/14/ PY - 2010 DA - 2010 Apr 14 KW - {Q1} KW - Obesity KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839618536?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2010+Annual+Meeting+of+the+Association+of+American+Geographers+%28AAG+2010%29&rft.atitle=Large+Scale+Built+Environment+Impact+on+US+Obesity+Epidemic-A+Multilevel+Approach&rft.au=Zhang%2C+Xingyou%3BHolt%2C+James%3BYang%2C+Jiawen%3BFrench%2C+Steven&rft.aulast=Zhang&rft.aufirst=Xingyou&rft.date=2010-04-14&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2010+Annual+Meeting+of+the+Association+of+American+Geographers+%28AAG+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://communicate.aag.org/eseries/aag_org/program/SessionList.cfm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-11 N1 - Last updated - 2011-01-14 ER - TY - CPAPER T1 - Creating Dynamic Series Charts Using Base SAS, SAS/GRAPH, and the Annotate Facility T2 - 2010 SAS Global Forum AN - 754167309; 5736485 JF - 2010 SAS Global Forum AU - Ju, Jun AU - Nowlin, Susan AU - Sestito, John Y1 - 2010/04/11/ PY - 2010 DA - 2010 Apr 11 KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754167309?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2010+SAS+Global+Forum&rft.atitle=Creating+Dynamic+Series+Charts+Using+Base+SAS%2C+SAS%2FGRAPH%2C+and+the+Annotate+Facility&rft.au=Ju%2C+Jun%3BNowlin%2C+Susan%3BSestito%2C+John&rft.aulast=Ju&rft.aufirst=Jun&rft.date=2010-04-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2010+SAS+Global+Forum&rft.issn=&rft_id=info:doi/ L2 - http://sgf2010.confnav.com/sgf2010/web/reports/abstract.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - JOUR T1 - Determinants of HIV Type 1 Shedding from Genital Ulcers among Men in South Africa AN - 754545359; 13269958 AB - Background. Our study evaluated correlates of human immunodeficiency virus (HIV)-1 lesional shedding among men with genital ulcer disease (GUD). Methods. Participants were recruited at primary health care clinics as part of a randomized trial of episodic acyclovir among men with GUD. This analysis was done among HIV-positive men identified at baseline. Participants were seroiogically screened for HIV infection, syphilis, and herpes simplex virus type 2 infection and for urethrltls and ulcer etiology by polymerase chain reaction. Plasma and genital ulcer HIV-1 loads and CD4 cell counts were quantified. We evaluated variables associated with the presence and quantity of HIV-1 in ulcers. Results. Among 387 HIV-positive men, the median plasma HIV-1 load and CD4 cell count were 87,200 copies/mL and 282 cells/mm super(3). Overall, 173 (45.6%) had detectable HIV-1 RNA in ulcers. Men with Trichomonas vaglnalls infection had higher ulcer viral loads on average than did those who were not infected (mean difference, 0.62; 95% confidence interval [CI], 0.07-1.2; P = .027). After multivariable analysis, higher plasma HIV-1 load (odds ratio [OR], 2.5; 95% CI, 1.7-3.5; P 5; OR, 3.6; 95% CI, 1.6-8.4; P = .002), and herpes seropositivlty (OR, 3.4; 95% CI, 1.7-7.0; P < .001) remained associated with increased odds of HIV-1 lesional shedding. Ulcers associated with herpes simplex virus type 2 infection were less likely to shed (OR, 0.6; 95% CI, 0.3-1.0; P = .05), compared with ulcers with unknown etiology. Conclusions. HIV-positive men should be screened and treated for GUD to minimize HIV shedding and transmission to unlnfected sexual partners. JF - Clinical Infectious Diseases AU - Paz-Bailey, G AU - Sternbera, M AU - Puren, A J AU - Steele, L AU - Lewis, DA AD - Center for Health Studies, Del Valle University of Guatemala, 18 avenlda 11-42 zona 15 Vista Hermosa III, Guatemala City, Guatemala, 01015, gpaz@gt.cdc.gov Y1 - 2010/04/01/ PY - 2010 DA - 2010 Apr 01 SP - 1060 EP - 1067 VL - 50 IS - 7 SN - 1058-4838, 1058-4838 KW - Health & Safety Science Abstracts; Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts KW - sexual behavior KW - homosexuality KW - Infection KW - acyclovir KW - Clinical trials KW - Herpes simplex KW - Disease transmission KW - Sexual partners KW - CD4 antigen KW - Human immunodeficiency virus 1 KW - Treponema pallidum KW - infection KW - Lesions KW - Polymerase chain reaction KW - South Africa KW - Syphilis KW - syphilis KW - Etiology KW - males KW - Health care KW - RNA KW - Human immunodeficiency virus KW - Ulcers KW - Trichomonas KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - V 22360:AIDS and HIV KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754545359?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+Infectious+Diseases&rft.atitle=Determinants+of+HIV+Type+1+Shedding+from+Genital+Ulcers+among+Men+in+South+Africa&rft.au=Paz-Bailey%2C+G%3BSternbera%2C+M%3BPuren%2C+A+J%3BSteele%2C+L%3BLewis%2C+DA&rft.aulast=Paz-Bailey&rft.aufirst=G&rft.date=2010-04-01&rft.volume=50&rft.issue=7&rft.spage=1060&rft.isbn=&rft.btitle=&rft.title=Clinical+Infectious+Diseases&rft.issn=10584838&rft_id=info:doi/10.1086%2F651115 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Sexual partners; Etiology; CD4 antigen; RNA; Ulcers; Polymerase chain reaction; acyclovir; Infection; Herpes simplex; Clinical trials; Syphilis; Disease transmission; sexual behavior; Health care; Human immunodeficiency virus; homosexuality; infection; Lesions; males; syphilis; Treponema pallidum; Human immunodeficiency virus 1; Trichomonas; South Africa DO - http://dx.doi.org/10.1086/651115 ER - TY - JOUR T1 - Evidence of Person-to-Person Transmission of Hepatitis E Virus during a Large Outbreak in Northern Uganda AN - 754544079; 13269951 AB - Background. Outbreaks of infection with hepatitis E virus (HEV) are frequently attributed to contaminated drinking water, even if direct evidence for this is lacking. Methods. We conducted several epldemlologic investigations during a large HEV infection outbreak in Uganda. Results. Of 10,535 residents, 3218 had HEV infection; of these, 2531 lived in households with >1 case. HEV was not detected in drinking water or zoonotlc sources. Twenty-five percent of cases occurred .8 weeks after onset of hepatitis in an index case in the household. Households with .2 cases were more likely to have a member(s) who attended a funeral, had close contact with a jaundiced person, or washed hands in a common basin with others (P < .05 for all). Conclusions. A high attack rate in households, lack of a common source of infection, and poor hygienic practices in households with .2 cases suggest person-to-person transmission of HEV during this outbreak. JF - Clinical Infectious Diseases AU - Teshale, E H AU - Grytdal, S P AU - Howard, C AU - Barry, V AU - Kamill, S AU - Drobeniuc, J AU - Hill, V R AU - Okware, S AU - Hu, D J AU - Hoimberg, S D AD - Div of Viral Hepatitis, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Malistop G-37, Atlanta, GA 30333, USA, eht4@cdc.gov Y1 - 2010/04/01/ PY - 2010 DA - 2010 Apr 01 SP - 1006 EP - 1010 VL - 50 IS - 7 SN - 1058-4838, 1058-4838 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Basins KW - Infection KW - Disease transmission KW - households KW - infection KW - Water-borne diseases KW - Hand KW - Uganda KW - Hepatitis E virus KW - outbreaks KW - Hepatitis KW - Drinking water KW - Hygiene KW - H 3000:Environment and Ecology KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754544079?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+Infectious+Diseases&rft.atitle=Evidence+of+Person-to-Person+Transmission+of+Hepatitis+E+Virus+during+a+Large+Outbreak+in+Northern+Uganda&rft.au=Teshale%2C+E+H%3BGrytdal%2C+S+P%3BHoward%2C+C%3BBarry%2C+V%3BKamill%2C+S%3BDrobeniuc%2C+J%3BHill%2C+V+R%3BOkware%2C+S%3BHu%2C+D+J%3BHoimberg%2C+S+D&rft.aulast=Teshale&rft.aufirst=E&rft.date=2010-04-01&rft.volume=50&rft.issue=7&rft.spage=1006&rft.isbn=&rft.btitle=&rft.title=Clinical+Infectious+Diseases&rft.issn=10584838&rft_id=info:doi/10.1086%2F651077 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Hepatitis; Hand; Basins; Hygiene; Drinking water; Infection; Disease transmission; households; Water-borne diseases; infection; outbreaks; Hepatitis E virus; Uganda DO - http://dx.doi.org/10.1086/651077 ER - TY - JOUR T1 - Traditional kinship system enhanced classic community-directed treatment with ivermectin (CDTI) for onchocerciasis control in Uganda AN - 746155190; 12980233 AB - The challenges of community-directed treatment with ivermectin (CDTI) for onchocerciasis control in Africa have been: maintaining a desired treatment coverage, demand for monetary incentives, high attrition of community distributors and low involvement of women. This study assessed how challenges could be minimised and performance improved using existing traditional kinship structures. In classic CDTI areas, community members decide upon selection criteria for community distributors, centers for health education and training, and methods of distributing ivermectin. In kinship enhanced CDTI, similar procedures were followed at the kinship level. We compared 14 randomly selected kinship enhanced CDTI communities with 25 classic CDTI communities through interviews of 447 and 750 household members and 127 and 64 community distributors respectively. Household respondents from kinship enhanced CDTI reported better performance (P < 0.001) than classic CDTI on the following measures of program effectiveness: (a) treatment coverage (b) decision on treatment location and (c) mobilization for CDTI activities. There were more female distributors in kinship enhanced CDTI than in classic CDTI. Attrition was not a problem. Kinship enhanced CDTI had a higher number of community distributors per population working among relatives, and were more likely to be involved in additional health care activities. The results suggest that kinship enhanced CDTI was more effective than classic CDTI. JF - Transactions of the Royal Society of Tropical Medicine and Hygiene AU - Katabarwa, Moses N AU - Habomugisha, Peace AU - Agunyo, Stella AU - McKelvey, Alanna C AU - Ogweng, Nicholas AU - Kwebiiha, Solomon AU - Byenume, Fredrick AU - Male, Ben AU - McFarland, Deborah AD - The Emory University/Carter Center, 1149 Ponce de Leon Avenue, Atlanta GA 30306, USA, mkataba@emory.edurzk5@cdc.gov Y1 - 2010/04// PY - 2010 DA - Apr 2010 SP - 265 EP - 272 PB - Royal Society of Tropical Medicine and Hygiene VL - 104 IS - 4 SN - 0035-9203, 0035-9203 KW - Health & Safety Science Abstracts UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/746155190?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Transactions+of+the+Royal+Society+of+Tropical+Medicine+and+Hygiene&rft.atitle=Traditional+kinship+system+enhanced+classic+community-directed+treatment+with+ivermectin+%28CDTI%29+for+onchocerciasis+control+in+Uganda&rft.au=Katabarwa%2C+Moses+N%3BHabomugisha%2C+Peace%3BAgunyo%2C+Stella%3BMcKelvey%2C+Alanna+C%3BOgweng%2C+Nicholas%3BKwebiiha%2C+Solomon%3BByenume%2C+Fredrick%3BMale%2C+Ben%3BMcFarland%2C+Deborah&rft.aulast=Katabarwa&rft.aufirst=Moses&rft.date=2010-04-01&rft.volume=104&rft.issue=4&rft.spage=265&rft.isbn=&rft.btitle=&rft.title=Transactions+of+the+Royal+Society+of+Tropical+Medicine+and+Hygiene&rft.issn=00359203&rft_id=info:doi/10.1016%2Fj.trstmh.2009.10.012 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2011-12-14 DO - http://dx.doi.org/10.1016/j.trstmh.2009.10.012 ER - TY - JOUR T1 - INCONSISTENT CONDOM USE AMONG YOUNG MEN WHO HAVE SEX WITH MEN, MALE SEX WORKERS, AND TRANSGENDERS IN THAILAND AN - 746128147; 12660945 AB - Young men who have sex with men (MSM) are at risk for HIV infection. We investigated inconsistent condom use among 827 sexually active young MSM (15-24 years), enrolled using venue-day-time sampling in Bangkok, Chiang Mai and Phuket, Thailand. Data was collected using palmtop computer-assisted self-interviewing. Of participants, 33.1% were regular MSM, 37.7% were male sex workers (MSWs) and 29.1% were trans-genders (TGs). Of MSM, 46.7%, of MSWs, 34.9% and of TGs, 52.3% reported recent inconsistent condom use. In multivariate analysis, receptive anal intercourse (MSM, MSWs), receptive and insertive anal intercourse, living alone and a history of sexual coercion (MSWs), not carrying a condom when interviewed (MSM, TGs), lower education, worrying about HIV infection and a history of sexually transmitted infections (TGs) were significantly and independently associated with inconsistent condom use. Interventions for young MSM are needed and must consider the distinct risk factors of MSM, MSWs, and TGs. JF - AIDS Education and Prevention AU - Chemnasiri, T AU - Netwong, T AU - Visarutratana, S AU - Varangrat, A AU - Li, A AU - Phanuphak, P AU - Jommaroeng, R AU - Akarasewi, P AU - van Griensven, F AD - Thailand Ministry of Public Health - U.S. Centers for Disease Control and Prevention Collaboration, DDC 7 Bldg., 4th Floor, Ministry of Public Health, Tivanon Road, Nonthaburi 11000 Thailand, tareeratc@th.cdc.gov Y1 - 2010/04// PY - 2010 DA - Apr 2010 SP - 100 EP - 109 VL - 22 IS - 2 SN - 0899-9546, 0899-9546 KW - Risk Abstracts; Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Historical account KW - Acquired immune deficiency syndrome KW - homosexuality KW - Thailand, Chacoengsao Prov., Bangkok KW - bisexuality KW - Infection KW - Condoms KW - infectious diseases KW - Workers KW - Multivariate analysis KW - intervention KW - Risk factors KW - infection KW - prevention KW - Sampling KW - sexually transmitted diseases KW - Sex KW - anal sex KW - Data processing KW - males KW - coercion KW - Prostitution KW - Education KW - Human immunodeficiency virus KW - condoms KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/746128147?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+Education+and+Prevention&rft.atitle=INCONSISTENT+CONDOM+USE+AMONG+YOUNG+MEN+WHO+HAVE+SEX+WITH+MEN%2C+MALE+SEX+WORKERS%2C+AND+TRANSGENDERS+IN+THAILAND&rft.au=Chemnasiri%2C+T%3BNetwong%2C+T%3BVisarutratana%2C+S%3BVarangrat%2C+A%3BLi%2C+A%3BPhanuphak%2C+P%3BJommaroeng%2C+R%3BAkarasewi%2C+P%3Bvan+Griensven%2C+F&rft.aulast=Chemnasiri&rft.aufirst=T&rft.date=2010-04-01&rft.volume=22&rft.issue=2&rft.spage=100&rft.isbn=&rft.btitle=&rft.title=AIDS+Education+and+Prevention&rft.issn=08999546&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Condoms; Workers; Data processing; Multivariate analysis; Risk factors; Prostitution; Sampling; Infection; Sex; Historical account; Acquired immune deficiency syndrome; anal sex; homosexuality; males; coercion; bisexuality; infectious diseases; Education; intervention; prevention; condoms; infection; sexually transmitted diseases; Human immunodeficiency virus; Thailand, Chacoengsao Prov., Bangkok ER - TY - JOUR T1 - Regression models to estimate total polychlorinated biphenyls in the general US population: 2001-2002 and 2003-2004 AN - 745927851; 13026179 AB - Certain polychlorinated biphenyls (PCB) have long half-lives and, despite the regulatory bans on the industrial pollutants that expose humans to PCB, are detectable in human serum. However, many of them are not detectable because of the small quantities that may be present in body fluids. For this reason, attempts have been made to estimate the total concentration of PCB (I4PCB) using the relationship between I4PCB and the concentrations of a few of the PCB congeners which can be reliably measured at detectable levels. PCB 153 or a combination of PCB 153,138, and 180 have previously been used for this purpose. However, because of the unique populations investigated in these studies, the results are not necessarily applicable to the racially/ethnically heterogeneous US population. We defined I4PCB as the sum of the concentrations of 12 PCB congeners, and sum of 33 PCB congeners for NHANES 2001-2002 and 2003-2004 respectively. We built regression models in a step-wise fashion using I4PCB as the dependent variable and age, race/ethnicity, and gender as the covariates for both whole-weight and lipid-adjusted data. In addition, concentration of PCB 153 was used as the continuous independent variable for 2001-2002 models, and PCB 153 and PCB 180 for 2003-2004 models respectively. R 2 for both models for NHANES 2001-2002 was >86%. The R 2 for both NHANES 2003-2004 models was >81%. Thus, the estimate of I4PCB for the general US population can be improved by considering common demographic variables, such as race/ethnicity, and selected congeners. JF - Chemosphere AU - Jain, Ram B AU - Wang, Richard Y AD - Centers for Disease Control and Prevention, Mail Stop F-47, 4770 Buford Highway, Chamblee, GA 30329, United States, rij0@cdc.gov Y1 - 2010/04// PY - 2010 DA - Apr 2010 SP - 243 EP - 252 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK VL - 79 IS - 3 SN - 0045-6535, 0045-6535 KW - Pollution Abstracts; Environment Abstracts KW - demography KW - USA KW - Age KW - Gender KW - PCB compounds KW - Ethnic groups KW - ENA 09:Land Use & Planning KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745927851?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemosphere&rft.atitle=Regression+models+to+estimate+total+polychlorinated+biphenyls+in+the+general+US+population%3A+2001-2002+and+2003-2004&rft.au=Jain%2C+Ram+B%3BWang%2C+Richard+Y&rft.aulast=Jain&rft.aufirst=Ram&rft.date=2010-04-01&rft.volume=79&rft.issue=3&rft.spage=243&rft.isbn=&rft.btitle=&rft.title=Chemosphere&rft.issn=00456535&rft_id=info:doi/10.1016%2Fj.chemosphere.2010.02.013 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2013-07-26 N1 - SubjectsTermNotLitGenreText - demography; Age; Gender; PCB compounds; Ethnic groups; USA DO - http://dx.doi.org/10.1016/j.chemosphere.2010.02.013 ER - TY - JOUR T1 - pfmdr1 Amplification and Fixation of pfcrt Chloroquine Resistance Alleles in Plasmodium falciparum in Venezuela AN - 745901789; 12580925 AB - Molecular tools are valuable for determining evolutionary history and the prevalence of drug-resistant malaria parasites. These tools have helped to predict decreased sensitivity to antimalarials and fixation of multidrug resistance genotypes in some regions. In order to assess how historical drug policies impacted Plasmodium falciparum in Venezuela, we examined molecular changes in genes associated with drug resistance. We examined pfmdr1 and pfcrt in samples from Sifontes, Venezuela, and integrated our findings with earlier work describing dhfr and dhps in these samples. We characterized pfmdr1 genotypes and copy number variation, pfcrt genotypes, and proximal microsatellites in 93 samples originating from surveillance from 2003 to 2004. Multicopy pfmdr1 was found in 12% of the samples. Two pfmdr1 alleles, Y184F/N1042D/D1246Y (37%) and Y184F/S1034C/N1042D/D1246Y (63%), were found. These alleles share ancestry, and no evidence of strong selective pressure on mutations was found. pfcrt chloroquine resistance alleles are fixed with two alleles: StctVMNT (91%) and SagtVMNT (9%). These alleles are associated with strong selection. There was also an association between pfcrt, pfmdr1, dhfr, and dhps genotypes/haplotypes. Duplication of pfmdr1 suggests a potential shift in mefloquine sensitivity in this region, which warrants further study. A bottleneck occurred in P. falciparum in Sifontes, Venezuela, and multidrug resistance genotypes are present. This population could be targeted for malaria elimination programs to prevent the possible spread of multidrug-resistant parasites. JF - Antimicrobial Agents & Chemotherapy AU - Griffing, Sean AU - Syphard, Luke AU - Sridaran, Sankar AU - McCollum, Andrea M AU - Mixson-Hayden, Tonya AU - Vinayak, Sumiti AU - Villegas, Leopoldo AU - Barnwell, John W AU - Escalante, Ananias A AU - Udhayakumar, Venkatachalam AD - Malaria Branch, Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, vxu0@cdc.gov Y1 - 2010/04// PY - 2010 DA - Apr 2010 SP - 1572 EP - 1579 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 54 IS - 4 SN - 0066-4804, 0066-4804 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Parasites KW - Human diseases KW - Allelles KW - Drug resistance KW - Malaria KW - Genotypes KW - Drug screening KW - Public health KW - Population genetics KW - Dihydrofolate reductase KW - Haplotypes KW - Mefloquine KW - Mutations KW - Microsatellites KW - Environmental impact KW - Chloroquine KW - Plasmodium falciparum KW - copy number KW - Venezuela KW - Multidrug resistance KW - Mutation KW - Evolution KW - A 01340:Antibiotics & Antimicrobials KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms KW - K 03310:Genetics & Taxonomy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745901789?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=pfmdr1+Amplification+and+Fixation+of+pfcrt+Chloroquine+Resistance+Alleles+in+Plasmodium+falciparum+in+Venezuela&rft.au=Griffing%2C+Sean%3BSyphard%2C+Luke%3BSridaran%2C+Sankar%3BMcCollum%2C+Andrea+M%3BMixson-Hayden%2C+Tonya%3BVinayak%2C+Sumiti%3BVillegas%2C+Leopoldo%3BBarnwell%2C+John+W%3BEscalante%2C+Ananias+A%3BUdhayakumar%2C+Venkatachalam&rft.aulast=Griffing&rft.aufirst=Sean&rft.date=2010-04-01&rft.volume=54&rft.issue=4&rft.spage=1572&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.01243-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-01 N1 - Number of references - 52 N1 - Last updated - 2015-10-28 N1 - SubjectsTermNotLitGenreText - Population genetics; Parasites; Human diseases; Mutations; Allelles; Environmental impact; Malaria; Genotypes; Public health; Drug resistance; Microsatellites; Chloroquine; Drug screening; copy number; Dihydrofolate reductase; Haplotypes; Multidrug resistance; Mefloquine; Mutation; Evolution; Plasmodium falciparum; Venezuela DO - http://dx.doi.org/10.1128/AAC.01243-09 ER - TY - JOUR T1 - Risk Behaviors and Psychosocial Stressors in the New York City House Ball Community: A Comparison of Men and Transgender Women Who Have Sex with Men AN - 745900252; 12593602 AB - The New York City House Ball community consists of social networks of racial/ethnic minority gay, lesbian or bisexual men and women, and transgender persons. HIV seroprevalence and interview data were obtained from a sample of community members to identify statistical differences in HIV prevalence, risk behavior, and psychosocial stressors between men who have sex with men (MSM) and transgender women. Of 301 MSM and 60 transgender women, 20% were HIV-infected and 73% were unaware of their infection, but rates did not differ by gender. Risk behavior and stressors were common in both groups, but transgender women were more likely to report exchange sex, stigmatization, and stressful life events. High rates of risk behavior and HIV in this special community warrant relevant HIV testing and prevention services. Transgender women in the community may be at even greater risk for HIV infection due to behaviors compounded by substantial psychosocial stressors. JF - AIDS and Behavior AU - Sanchez, Travis AU - Finlayson, Teresa AU - Murrill, Christopher AU - Guilin, Vincent AU - Dean, Laura AD - Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road NE, M/S E-46, Atlanta, GA, 30333, USA, TSanchez@cdc.gov Y1 - 2010/04// PY - 2010 DA - Apr 2010 SP - 351 EP - 358 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 14 IS - 2 SN - 1090-7165, 1090-7165 KW - Risk Abstracts; Virology & AIDS Abstracts KW - Acquired immune deficiency syndrome KW - Houses KW - Data processing KW - Statistics KW - Housing KW - Risk taking KW - males KW - bisexuality KW - Infection KW - Sexual behavior KW - Social interactions KW - USA, New York, New York City KW - Human immunodeficiency virus KW - Risk factors KW - Bisexual KW - Residential areas KW - infection KW - Females KW - Urban areas KW - Sex KW - V 22360:AIDS and HIV KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745900252?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Risk+Behaviors+and+Psychosocial+Stressors+in+the+New+York+City+House+Ball+Community%3A+A+Comparison+of+Men+and+Transgender+Women+Who+Have+Sex+with+Men&rft.au=Sanchez%2C+Travis%3BFinlayson%2C+Teresa%3BMurrill%2C+Christopher%3BGuilin%2C+Vincent%3BDean%2C+Laura&rft.aulast=Sanchez&rft.aufirst=Travis&rft.date=2010-04-01&rft.volume=14&rft.issue=2&rft.spage=351&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-009-9610-6 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Houses; Statistics; Data processing; Risk factors; Bisexual; Infection; Social interactions; Sex; Acquired immune deficiency syndrome; Housing; Human immunodeficiency virus; infection; Residential areas; males; Risk taking; Females; bisexuality; Sexual behavior; Urban areas; USA, New York, New York City DO - http://dx.doi.org/10.1007/s10461-009-9610-6 ER - TY - JOUR T1 - Sexuality education policies and sexually transmitted disease rates in the United States of America AN - 745638237; 13033530 AB - The aim of the study was to test for relationships between state-level sex educational policies and sexually transmitted disease (STD) rates. We analysed US case reports of gonorrhoea and chlamydial infection for 2001-2005 against state policies for abstinence coverage in sexuality education, using the proportion of the population per state who identified as black (aged 15-24 years) as a covariate. We also tested for effects on 15-19 year olds versus 35-39 year olds and tuberculosis rates (the latter to ensure findings applied only to STD). States with no mandates for abstinence had the lowest mean rates of infection among the overall population and among adolescents. States with mandates emphasizing abstinence had the highest rates; states with mandates to cover (but not emphasize) abstinence fell in between. Rates in some states covering abstinence changed faster than in others, as reflected in sharper declines (gonorrhoea) or slower increases (chlamydial infection). These effects were not shown for tuberculosis or 35-39 year olds. Having no abstinence education policy has no apparent effect on STD rates for adolescents. For states with elevated rates, policies mandating coverage may be useful, although policies emphasizing abstinence show no benefit. JF - International Journal of STD & AIDS AU - Hogben, M AU - Chesson, H AU - Aral, SO AD - Division of STD Prevention, Centers for Disease Control and Prevention, Mail Stop E-44, Atlanta, GA 30333, USA, mhogben@cdc.gov Y1 - 2010/04// PY - 2010 DA - Apr 2010 SP - 293 EP - 297 VL - 21 IS - 4 SN - 0956-4624, 0956-4624 KW - Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - sexual behavior KW - Acquired immune deficiency syndrome KW - Sexually-transmitted diseases KW - Mycobacterium KW - Infection KW - Sexuality KW - State policy KW - infection KW - Tuberculosis KW - State policies KW - sexually transmitted diseases KW - Adolescents KW - Sex KW - Adolescence KW - tuberculosis KW - USA KW - Education KW - Case reports KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745638237?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+STD+%26+AIDS&rft.atitle=Sexuality+education+policies+and+sexually+transmitted+disease+rates+in+the+United+States+of+America&rft.au=Hogben%2C+M%3BChesson%2C+H%3BAral%2C+SO&rft.aulast=Hogben&rft.aufirst=M&rft.date=2010-04-01&rft.volume=21&rft.issue=4&rft.spage=293&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+STD+%26+AIDS&rft.issn=09564624&rft_id=info:doi/10.1258%2Fijsa.2010.009589 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Sexuality; State policy; Case reports; Sexually-transmitted diseases; Adolescence; Tuberculosis; Infection; Sex; tuberculosis; sexual behavior; Acquired immune deficiency syndrome; Education; infection; State policies; Adolescents; sexually transmitted diseases; Mycobacterium; USA DO - http://dx.doi.org/10.1258/ijsa.2010.009589 ER - TY - JOUR T1 - The bba64 gene of Borrelia burgdorferi, the Lyme disease agent, is critical for mammalian infection via tick bite transmission AN - 744615711; 13003163 AB - The spirochetal agent of Lyme disease, Borrelia burgdorferi, is transmitted by bites of Ixodes ticks to mammalian reservoir hosts and humans. The mechanism(s) by which the organism is trafficked from vector to host is poorly understood. In this study, we demonstrate that a B. burgdorferi mutant strain deficient in the synthesis of the bba64 gene product was incapable of infecting mice via tick bite even though the mutant was (i) infectious in mice when introduced by needle inoculation, (ii) acquired by larval ticks feeding on infected mice, and (iii) able to persist through tick molting stages. This finding of a B. burgdorferi gene required for pathogen transfer and/or survival from the tick to the susceptible host represents an important breakthrough toward understanding transmission mechanisms involved for the Lyme disease agent. JF - Proceedings of the National Academy of Sciences, USA AU - Gilmore, Robert D AU - Howison, Rebekah R AU - Dietrich, Gabrielle AU - Patton, Toni G AU - Clifton, Dawn R AU - Carroll, James A AD - Bacterial Diseases Branch, Division of Vector-Borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80521, rbg9@cdc.gov. Y1 - 2010/04// PY - 2010 DA - Apr 2010 SP - 7515 EP - 7520 PB - National Academy of Sciences, 2101 Constitution Ave. Washington DC 20418 USA VL - 107 IS - 16 SN - 0027-8424, 0027-8424 KW - Microbiology Abstracts B: Bacteriology; Entomology Abstracts KW - Bites KW - Disease transmission KW - Feeding KW - Infection KW - Inoculation KW - Lyme disease KW - Molting KW - Pathogens KW - Survival KW - Vectors KW - Ixodes KW - Borrelia burgdorferi KW - Ixodidae KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/744615711?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Proceedings+of+the+National+Academy+of+Sciences%2C+USA&rft.atitle=The+bba64+gene+of+Borrelia+burgdorferi%2C+the+Lyme+disease+agent%2C+is+critical+for+mammalian+infection+via+tick+bite+transmission&rft.au=Gilmore%2C+Robert+D%3BHowison%2C+Rebekah+R%3BDietrich%2C+Gabrielle%3BPatton%2C+Toni+G%3BClifton%2C+Dawn+R%3BCarroll%2C+James+A&rft.aulast=Gilmore&rft.aufirst=Robert&rft.date=2010-04-01&rft.volume=107&rft.issue=16&rft.spage=7515&rft.isbn=&rft.btitle=&rft.title=Proceedings+of+the+National+Academy+of+Sciences%2C+USA&rft.issn=00278424&rft_id=info:doi/10.1073%2Fpnas.1000268107 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - Feeding; Bites; Inoculation; Survival; Vectors; Pathogens; Infection; Molting; Disease transmission; Lyme disease; Ixodes; Borrelia burgdorferi; Ixodidae DO - http://dx.doi.org/10.1073/pnas.1000268107 ER - TY - JOUR T1 - Emergency Department Visits Made by Patients with Sickle Cell Disease: A Descriptive Study, 1999-2007 AN - 742720668; 201012541 AB - Background: Patients with sickle cell disease (SCD) often use emergency department services to obtain medical care. Limited information is available about emergency department use among patients with SCD. Purpose: This study assessed characteristics of emergency department visits made nationally by patients with SCD. Methods: Data from the National Hospital Ambulatory Medical Care Survey (NHAMCS) for the years 1999-2007 were analyzed. The NHAMCS is a survey of hospital emergency department & outpatient visits. Emergency department visits by patients with SCD were identified using ICD-9-CM codes, & nationally weighted estimates were calculated. Results: On average, approximately 197,333 emergency department visits were estimated to have occurred each year between 1999 & 2007 with SCD as one of the diagnoses listed. The expected source of payment was private insurance for 14%, Medicaid/State Children's Health Insurance Program for 58%, Medicare for 14%, & other/unknown for 15%. Approximately 29% of visits resulted in hospital admission; this was 37% among patients aged 0-19 years, & 26% among patients aged =20 years. The episode of care was indicated as a follow-up visit for 23% of the visits. Patient-cited reasons for the emergency department visit included chest pain (11%); other pain or unspecified pain (67%); fever/infection (6%); & shortness of breath/breathing problem/cough (5%), among other reasons. Conclusions: Substantial numbers of emergency department visits occur among people with SCD. The most common reason for the emergency department visits is pain symptoms. The findings of this study can help to improve health services delivery & utilization among patients with SCD. Adapted from the source document. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Yusuf, Hussain R AU - Atrash, Hani K AU - Grosse, Scott D AU - Parker, Christopher S AU - Grant, Althea M AD - Div Blood Disorders, National Center Birth Defects Developmental Disabilities, CDC, Atlanta hyusuf@cdc.gov Y1 - 2010/04// PY - 2010 DA - April 2010 SP - S536 EP - S541 PB - Elsevier Science, New York NY VL - 38 IS - S4 SN - 0749-3797, 0749-3797 KW - Health care KW - Accident and emergency departments KW - Sickle cell anaemia KW - Pain KW - Fevers KW - Hospitals KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742720668?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Emergency+Department+Visits+Made+by+Patients+with+Sickle+Cell+Disease%3A+A+Descriptive+Study%2C+1999-2007&rft.au=Yusuf%2C+Hussain+R%3BAtrash%2C+Hani+K%3BGrosse%2C+Scott+D%3BParker%2C+Christopher+S%3BGrant%2C+Althea+M&rft.aulast=Yusuf&rft.aufirst=Hussain&rft.date=2010-04-01&rft.volume=38&rft.issue=S4&rft.spage=S536&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2010.01.001 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-05-10 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Accident and emergency departments; Hospitals; Pain; Sickle cell anaemia; Health care; Fevers DO - http://dx.doi.org/10.1016/j.amepre.2010.01.001 ER - TY - JOUR T1 - The Universal Data Collection Surveillance System for Rare Bleeding Disorders AN - 742719937; 201011948 AB - Since 1998, the CDC has coordinated a national public health surveillance project -- the Universal Data Collection (UDC) program -- on chronic, rare, inherited bleeding disorders. In this program, uniform data are gathered through a network of 130 hemophilia treatment centers (HTCs) throughout the U.S. & its territories. Initially, the program was designed to address two primary goals: (1) establishment of a blood-safety monitoring system among people with bleeding disorders, & (2) collection of a uniform set of clinical outcomes data that could be used to monitor trends in the prevalence of infectious diseases & joint complications among this population. To this end, the program has been acquiring useful longitudinal data to monitor complications of bleeding disorders. For example, with the establishment of range-of-motion measurements for joints as required data elements, a large database has been developed for studies examining risk factors for joint-disease progression. The UDC program data have been used to provide evidence for a national prevention campaign to promote the need for patients with hemophilia to establish or maintain a healthy weight to help prevent joint disease. Risk factors leading to complications such as joint infection have also been identified. The application of geographic information systems technology to UDC program data has helped identify needs for outreach & availability of blood products & sources of care. Future analyses of data collected on babies, women, & individuals with rarer bleeding disorders than hemophilia will provide further information, leading to improved public health prevention strategies. Adapted from the source document. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Soucie, J Michael AU - McAlister, Sally AU - McClellan, Ann AU - Oakley, Meredith AU - Su, Ying AD - Div Blood Disorders, National Center Birth Defects Developmental Disabilities, CDC, Atlanta, GA msoucie@cdc.gov Y1 - 2010/04// PY - 2010 DA - April 2010 SP - S475 EP - S481 PB - Elsevier Science, New York NY VL - 38 IS - S4 SN - 0749-3797, 0749-3797 KW - Clinical outcomes KW - Risk factors KW - Bleeding KW - Geographic information systems KW - Uniforms KW - Infection KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742719937?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=The+Universal+Data+Collection+Surveillance+System+for+Rare+Bleeding+Disorders&rft.au=Soucie%2C+J+Michael%3BMcAlister%2C+Sally%3BMcClellan%2C+Ann%3BOakley%2C+Meredith%3BSu%2C+Ying&rft.aulast=Soucie&rft.aufirst=J&rft.date=2010-04-01&rft.volume=38&rft.issue=S4&rft.spage=S475&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2009.12.023 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-05-10 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Bleeding; Risk factors; Uniforms; Geographic information systems; Infection; Clinical outcomes DO - http://dx.doi.org/10.1016/j.amepre.2009.12.023 ER - TY - JOUR T1 - The Public Health Response to Blood Disorders AN - 742718967; 201008923 AB - Nonmalignant blood disorders meet all criteria for qualifying, as a group, as a very important public health problem with serious morbidities affecting over 1 million Americans every year, not including an additional 8 million individuals suffering from anemia. Many of these conditions & the morbidities & mortalities associated with them are, to a large extent, preventable. Further, the changing demographic composition of the American population is sure to increase the number of individuals affected by these conditions. Yet, nonmalignant blood disorders have not been recognized as important public health priorities. Immediate action is needed to meet the increasing challenge of blood disorders in public health. We propose a national, comprehensive, organized, coordinated, institutionalized, sustainable public health response to blood disorders based on the three core functions & the ten essential services of public health. Immediate action needs to be taken to improve surveillance & monitoring, increase public & provider awareness, increase the use of evidence-based practices, & enhance epidemiologic research on the causes, prevention, & treatment of conditions resulting in adverse outcomes. Adapted from the source document. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Atrash, Hani K AU - Parker, Christopher S AD - Div Blood Disorders, National Center Birth Defects Developmental Disabilities, CDC, Atlanta, GA Hatrash@cdc.gov Y1 - 2010/04// PY - 2010 DA - April 2010 SP - S451 EP - S455 PB - Elsevier Science, New York NY VL - 38 IS - S4 SN - 0749-3797, 0749-3797 KW - Suffering KW - American people KW - Blood disorders KW - Surveillance KW - Morbidity KW - Public health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742718967?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=The+Public+Health+Response+to+Blood+Disorders&rft.au=Atrash%2C+Hani+K%3BParker%2C+Christopher+S&rft.aulast=Atrash&rft.aufirst=Hani&rft.date=2010-04-01&rft.volume=38&rft.issue=S4&rft.spage=S451&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2010.01.006 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-05-10 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Public health; Blood disorders; Morbidity; American people; Suffering; Surveillance DO - http://dx.doi.org/10.1016/j.amepre.2010.01.006 ER - TY - JOUR T1 - Health Status and Healthcare Use in a National Sample of Children with Sickle Cell Disease AN - 742717652; 201009133 AB - Background: There is a paucity of population-based data describing health status & use of health services among children with sickle cell disease (SCD). Purpose: This study provides estimates of co-occurring conditions, health impact & utilization, & barriers to care for a national sample of children with SCD. Methods: Data were derived from the 1997-2005 National Health Interview Survey Child Sample Core. The study included 192 children aged 0-17 years with SCD whose race was reported as black or African-American, & 19,335 children without SCD of the same age & race. Parents or other knowledgeable adults reported on medical & developmental conditions, health status, & healthcare use & access. Results: After adjusting for demographic characteristics, black children with SCD had higher odds of frequent severe headaches or migraines, intellectual disabilities, regular use of prescription medication, & fair or poor health status compared with black children without SCD. While healthcare & special education services use were generally higher for black children with SCD than for black children in the general population, those with SCD also had higher odds of reporting delays in accessing health care. Conclusions: The health burden for children with SCD & their families is profound & may be exacerbated by barriers to accessing comprehensive medical care. Additional study of the extent of unmet needs for U.S. children with SCD is warranted. Adapted from the source document. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Boulet, Sheree L AU - Yanni, Emad A AU - Creary, Melissa S AU - Olney, Richard S AD - Div Blood Disorders, National Center Birth Defects Developmental Disabilities, CDC, Atlanta sboulet@cdc.gov Y1 - 2010/04// PY - 2010 DA - April 2010 SP - S528 EP - S535 PB - Elsevier Science, New York NY VL - 38 IS - S4 SN - 0749-3797, 0749-3797 KW - Health care KW - Migraine KW - Health status KW - Sickle cell anaemia KW - Health KW - Children KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742717652?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Health+Status+and+Healthcare+Use+in+a+National+Sample+of+Children+with+Sickle+Cell+Disease&rft.au=Boulet%2C+Sheree+L%3BYanni%2C+Emad+A%3BCreary%2C+Melissa+S%3BOlney%2C+Richard+S&rft.aulast=Boulet&rft.aufirst=Sheree&rft.date=2010-04-01&rft.volume=38&rft.issue=S4&rft.spage=S528&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2010.01.003 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-05-10 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Children; Health care; Health status; Health; Sickle cell anaemia; Migraine DO - http://dx.doi.org/10.1016/j.amepre.2010.01.003 ER - TY - JOUR T1 - Sickle Cell Disease and Pregnancy Outcomes: Women of African Descent AN - 742717377; 201008979 AB - Background: Sickle cell disease (SCD) is a severe hematologic condition that presents unique complications among affected pregnant women. Many studies of adverse perinatal outcomes associated with SCD are limited by small samples or fail to consider important risk factors. Purpose: This study compared perinatal outcomes among women of African ancestry with & without SCD in a large, population-based sample. Methods: Data from the Massachusetts Pregnancy to Early Life Longitudinal (PELL) Data System were analyzed during June-August 2009 to identify in-state deliveries to resident women of African descent. Logistic regression analyses compared perinatal outcomes for deliveries among women with & without SCD, adjusted for maternal age, education, parity, plurality, insurance status, adequacy of prenatal care, smoking during pregnancy, & infant gender. Results: During 1998-2006, there were 116,076 deliveries to 84,561 women; SCD prevalence was 0.6%. Adjusted odds of fetal death among deliveries to women with SCD were 2.2 times those among women without SCD (95% CI=1.2, 4.2). Compared to women without SCD, the odds of preterm delivery, low birth weight, & having babies small for gestational age (SGA) among women with SCD were 1.5 (95% CI=1.2, 1.8); 1.7 (95% CI=1.1, 2.6); & 1.3 (95% CI=1.0, 1.7), respectively. Sickle cell disease was positively associated with cesarean delivery & inductions. Conclusions: Population-based linked data systems are useful for assessing risks of adverse health outcomes among women with specific medical conditions, such as SCD. Women with SCD should seek preconception care to identify & modify risk behaviors & receive counseling regarding potential adverse sequelae associated with pregnancy-related morbidity & preterm delivery. Adapted from the source document. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Barfield, Wanda D AU - Barradas, Danielle T AU - Manning, Susan E AU - Kotelchuck, Milton AU - Shapiro-Mendoza, Carrie K AD - Div Reproductive Health, National Center Chronic Disease Prevention Health Promotion, CDC, Atlanta wbarfield@cdc.gov Y1 - 2010/04// PY - 2010 DA - April 2010 SP - S542 EP - S549 PB - Elsevier Science, New York NY VL - 38 IS - S4 SN - 0749-3797, 0749-3797 KW - Gender KW - Premature births KW - Perinatal KW - Women KW - Sickle cell anaemia KW - Pregnant women KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742717377?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Sickle+Cell+Disease+and+Pregnancy+Outcomes%3A+Women+of+African+Descent&rft.au=Barfield%2C+Wanda+D%3BBarradas%2C+Danielle+T%3BManning%2C+Susan+E%3BKotelchuck%2C+Milton%3BShapiro-Mendoza%2C+Carrie+K&rft.aulast=Barfield&rft.aufirst=Wanda&rft.date=2010-04-01&rft.volume=38&rft.issue=S4&rft.spage=S542&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2009.12.020 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-05-10 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Women; Pregnant women; Perinatal; Sickle cell anaemia; Premature births; Gender DO - http://dx.doi.org/10.1016/j.amepre.2009.12.020 ER - TY - JOUR T1 - Venous Thromboembolism: A Public Health Concern AN - 742715293; 201009023 AB - Venous thromboembolism (VTE), defined as deep vein thrombosis, pulmonary embolism, or both, affects an estimated 300,000-600,000 individuals in the U.S. each year, causing considerable morbidity and mortality. It is a disorder that can occur in all races and ethnicities, all age groups, and both genders. With many of the known risk factors -- advanced age, immobility, surgery, obesity -- increasing in society, VTE is an important and growing public health problem. Recently, a marked increase has occurred in federal and national efforts to raise awareness and acknowledge the need for VTE prevention. Yet, many basic public health functions -- surveillance, research, and awareness -- are still needed. Learning and understanding more about the burden and causes of VTE, and raising awareness among the public and healthcare providers through a comprehensive public health approach, has enormous potential to prevent and reduce death and morbidity from deep vein thrombosis and pulmonary embolism throughout the U.S. Adapted from the source document. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Beckman, Michele G AU - W Hooper, Craig AU - Critchley, Sara E AU - Ortel, Thomas L AD - Div Blood Disorders, National Center Birth Defects Developmental Disabilities, CDC, Atlanta mbeckman@cdc.gov Y1 - 2010/04// PY - 2010 DA - April 2010 SP - S495 EP - S501 PB - Elsevier Science, New York NY VL - 38 IS - S4 SN - 0749-3797, 0749-3797 KW - Deep vein thrombosis KW - Pulmonary embolism KW - Gender KW - Venous thrombosis KW - Morbidity-Mortality KW - Public health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742715293?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Venous+Thromboembolism%3A+A+Public+Health+Concern&rft.au=Beckman%2C+Michele+G%3BW+Hooper%2C+Craig%3BCritchley%2C+Sara+E%3BOrtel%2C+Thomas+L&rft.aulast=Beckman&rft.aufirst=Michele&rft.date=2010-04-01&rft.volume=38&rft.issue=S4&rft.spage=S495&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2009.12.017 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-05-10 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Public health; Deep vein thrombosis; Venous thrombosis; Pulmonary embolism; Morbidity-Mortality; Gender DO - http://dx.doi.org/10.1016/j.amepre.2009.12.017 ER - TY - JOUR T1 - The association between childhood asthma prevalence and monitored air pollutants in metropolitan areas, United States, 2001-2004. AN - 733702703; 20117766 AB - Air pollution exposure has been linked to adverse respiratory health outcomes among children, primarily in studies of acute exposures that are often in limited geographic areas. We sought to assess the association between chronic outdoor air pollution exposure, as measured by 12-month averages by county, and asthma among children in metropolitan areas across the nation. Eligible children included those aged 3-17 years residing in US metropolitan areas who were sampled in the 2001-2004 National Health Interview Survey (N=34,073). 12-month average air pollutant levels for sulfur dioxide, nitrogen dioxide, ozone and particulate matter were compiled by county for 2000-2004. Eligible children were linked to pollutant levels for the previous 12 months for their county of residence. Adjusted odds ratios of having current asthma or an asthma attack in the past 12 months were estimated in single pollutant logistic regression models. Children in counties with ozone and, to a less consistent degree, particulate matter levels in the highest quartile were more likely to have current asthma and/or a recent asthma attack than children residing in counties with the lowest pollution levels; the adjusted odds for current asthma for the highest quartile of estimated ozone exposure was 1.56 (95% confidence interval [CI]: 1.15, 2.10) and for recent asthma attack 1.38 (95% CI: 0.99, 1.91). No associations were found with sulfur dioxide or nitrogen dioxide levels. Although the current US standard for ozone is based on short-term exposure, this cross-sectional study suggests that chronic (12-month) exposure to ozone and particles is related to asthma outcomes among children in metropolitan areas throughout the US. (c) 2009 Elsevier Inc. All rights reserved. JF - Environmental research AU - Akinbami, Lara J AU - Lynch, Courtney D AU - Parker, Jennifer D AU - Woodruff, Tracey J AD - National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD 20782, USA. lea8@cdc.gov Y1 - 2010/04// PY - 2010 DA - April 2010 SP - 294 EP - 301 VL - 110 IS - 3 KW - Air Pollutants KW - 0 KW - Particulate Matter KW - Sulfur Dioxide KW - 0UZA3422Q4 KW - Ozone KW - 66H7ZZK23N KW - Nitrogen Dioxide KW - S7G510RUBH KW - Index Medicus KW - Air Pollution -- statistics & numerical data KW - Nitrogen Dioxide -- analysis KW - Ozone -- analysis KW - Sulfur Dioxide -- analysis KW - Humans KW - Environmental Exposure -- analysis KW - Child KW - Particulate Matter -- analysis KW - Child, Preschool KW - Cross-Sectional Studies KW - Epidemiological Monitoring KW - Adolescent KW - United States -- epidemiology KW - Female KW - Male KW - Cities -- statistics & numerical data KW - Environmental Monitoring KW - Asthma -- epidemiology KW - Air Pollutants -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733702703?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+research&rft.atitle=The+association+between+childhood+asthma+prevalence+and+monitored+air+pollutants+in+metropolitan+areas%2C+United+States%2C+2001-2004.&rft.au=Akinbami%2C+Lara+J%3BLynch%2C+Courtney+D%3BParker%2C+Jennifer+D%3BWoodruff%2C+Tracey+J&rft.aulast=Akinbami&rft.aufirst=Lara&rft.date=2010-04-01&rft.volume=110&rft.issue=3&rft.spage=294&rft.isbn=&rft.btitle=&rft.title=Environmental+research&rft.issn=1096-0953&rft_id=info:doi/10.1016%2Fj.envres.2010.01.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-03-24 N1 - Date created - 2010-03-12 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.envres.2010.01.001 ER - TY - JOUR T1 - Prevalence and correlates of depressive symptoms among United States adults with disabilities using assistive technology AN - 57350037; 201007855 AB - Objectives To estimate the prevalence of current depressive symptoms (CDS) among adults that reported disabilities requiring the use of assistive technology (AT) and those that did not, and to examine the sociodemographic, comorbidity, health behavior, and social support correlates of this condition in adults who use AT. Methods Data from the 2006 Behavioral Risk Factor Surveillance System, a standardized telephone survey among U.S. adults, were analyzed (n = 195,033). The Patient Health Questionnaire diagnostic algorithm was used to identify CDS. Results AT users were significantly more likely than AT non-users to have CDS (age-standardized: 30.4% vs. 7.4%). Among AT users, there was a dose-response relationship between depression severity and increased prevalence of health conditions, obesity, smoking, and physical inactivity. In the full covariate logistic regression model, the strongest sociodemographic variables associated with CDS among AT users were age and employment status. Other variables strongly associated with CDS were lack of social support and anxiety. Conclusions An integrated approach to health care should be taken with adults who use AT. AT service providers, primary health care providers, and other care givers should be alert to the possibility of depression in AT users; and opportunities to prevent, detect, and treat depression among this population should not be missed. [Copyright Elsevier B.V.] JF - Preventive Medicine AU - Okoro, Catherine A AU - Strine, Tara W AU - Balluz, Lina S AU - Crews, John E AU - Mokdad, Ali H AD - Epidemiologist, Behavioral Surveillance Branch, Division of adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, US Centers for Disease Control and Prevention, 4770 Buford Highway, NE, Mailstop K66, Atlanta, GA 30341, USA Cokoro@cdc.gov Y1 - 2010/04// PY - 2010 DA - April 2010 SP - 204 EP - 209 PB - Elsevier Ltd, The Netherlands VL - 50 IS - 4 SN - 0091-7435, 0091-7435 KW - Disability Assistive technology Assistive devices Special equipment Depressive symptoms Anxiety disorders Smoking Epidemiology Age BRFSS KW - Social support KW - Disabled people KW - Sociodemographic aspects KW - Prevalence KW - Anxiety-Depression KW - Technical aids KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/57350037?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Preventive+Medicine&rft.atitle=Prevalence+and+correlates+of+depressive+symptoms+among+United+States+adults+with+disabilities+using+assistive+technology&rft.au=Okoro%2C+Catherine+A%3BStrine%2C+Tara+W%3BBalluz%2C+Lina+S%3BCrews%2C+John+E%3BMokdad%2C+Ali+H&rft.aulast=Okoro&rft.aufirst=Catherine&rft.date=2010-04-01&rft.volume=50&rft.issue=4&rft.spage=204&rft.isbn=&rft.btitle=&rft.title=Preventive+Medicine&rft.issn=00917435&rft_id=info:doi/10.1016%2Fj.ypmed.2010.01.008 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-04-07 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Technical aids; Disabled people; Anxiety-Depression; Prevalence; Social support; Sociodemographic aspects DO - http://dx.doi.org/10.1016/j.ypmed.2010.01.008 ER - TY - JOUR T1 - Subpopulations of Francisella tularensis ssp. tularensis and holarctica: identification and associated epidemiology AN - 1011206324; 16488698 AB - Tularemia is primarily caused by two subspecies of Francisella tularensis worldwide, ssp. tularensis (type A) and ssp. holarctica (type B), which were originally delineated by phenotypic differences. Application of molecular typing methods to investigate population structure of F. tularensis has confirmed that catagorizing the two subspecies via phenotypic characteristics corresponds with genotypic differentiation. In addition, genotyping methods have demonstrated that both subspecies, type A and type B, can be further distinguished into subpopulations and, in some cases, biological relevance has been ascribed to these identified subpopulations. Genetic variation among both type A and type B subpopulations has been shown to correlate with differences in geographic distribution and has also been coupled to distinct ecological niches, animal hosts and replication foci. Among type A subpopulations, strain variation is linked to differing clinical manifestations in humans and virulence in mice. This article will highlight our current understanding of F. tularensis subpopulations, including methods for their detection, their observed epidemiologic differences, implications for public health and basic research programs, as well as future challenges yet to be solved. JF - Future Microbiology AU - Petersen, Jeannine M AU - Molins, Claudia R AD - Centers for Disease Control & Prevention, Division of Vector-Borne Diseases, Bacterial Diseases Branch, 3150 Rampart Road, Fort Collins, CO 80521, USA., jpetersen@cdc.gov Y1 - 2010/04// PY - 2010 DA - Apr 2010 SP - 649 EP - 661 PB - Future Science Group (FSG), Unitec House, 2 Albert Place London N3 1QB United Kingdom VL - 5 IS - 4 SN - 1746-0913, 1746-0913 KW - Microbiology Abstracts B: Bacteriology KW - Differentiation KW - Epidemiology KW - Genetic diversity KW - Genotyping KW - Geographical distribution KW - Niches KW - Population structure KW - Public health KW - Replication KW - Research programs KW - Subpopulations KW - Tularemia KW - Virulence KW - Francisella tularensis KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1011206324?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Future+Microbiology&rft.atitle=Subpopulations+of+Francisella+tularensis+ssp.+tularensis+and+holarctica%3A+identification+and+associated+epidemiology&rft.au=Petersen%2C+Jeannine+M%3BMolins%2C+Claudia+R&rft.aulast=Petersen&rft.aufirst=Jeannine&rft.date=2010-04-01&rft.volume=5&rft.issue=4&rft.spage=649&rft.isbn=&rft.btitle=&rft.title=Future+Microbiology&rft.issn=17460913&rft_id=info:doi/10.2217%2Ffmb.10.17 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Number of references - 68 N1 - Last updated - 2012-05-18 N1 - SubjectsTermNotLitGenreText - Geographical distribution; Replication; Subpopulations; Genotyping; Niches; Genetic diversity; Public health; Virulence; Differentiation; Tularemia; Epidemiology; Population structure; Research programs; Francisella tularensis DO - http://dx.doi.org/10.2217/fmb.10.17 ER - TY - JOUR T1 - HIV genital shedding and safety of Carraguard use by HIV-infected women: a crossover trial in Thailand AN - 744667802; 12572365 AB - Objective: To evaluate the safety, including impact on genital HIV RNA shedding, of Carraguard vaginal gel in HIV-infected women. Design: This is a randomized, controlled, crossover study of Carraguard in HIV-infected women in Thailand. Methods: Each woman (CD4 super(+) cell count 51-500cells/kl and not on antiretroviral therapy) used each treatment (Carraguard, methyicellulose placebo, and no-product) once daily for 7 days during each 1-month period (3-week wash-out). Women were randomized to one of the six possible treatment sequences. Safety assessments were conducted at baseline (pregel), 15 min postgel, day 7, and day 14, and included HIV RNA measurements in cervicovaginal lavage (CVL) specimens. Results: Sixty women were enrolled, and 99% of scheduled study visits were completed. At baseline, median age (34 years), CD4 super(+) lymphocyte count (296cells/kl), plasma HIV viral load (4.6 log sub(10) copies/ml), CVL HIV viral load (3.1 log sub(10) total copies per CVL), and sexual behaviors were similar among randomization groups. HIV viral load, leukocyte and hemoglobin levels, and epithelial cell counts in CVLs were lower 15 min after application of Carraguard or placebo compared with no product; CVL HIV viral load was still lower at day 7 but returned to baseline by day 14. Carraguard use was not associated with prevalent or incident genital findings or abnormal vaginal flora. Conclusion: Carraguard appears to be well tolerated for once-daily vaginal use by HIV-infected women. The observed reduction in CVL HIV viral load in the gel months may be clinically relevant but could have resulted from interference with sample collection by study gels. JF - AIDS AU - McLean, CA AU - van de Wijgert, JHHM AU - Jones, HE AU - Karon, J M AU - McNicoll, J M AU - Whitehead, S J AU - Braunstein, S AU - Achalapong, J AU - Chaikummao, S AU - Tappero, J W AU - Markowitz, LE AU - Kilmarx, PH AD - Centers for Disease Control and Prevention, 1600 Clifton Road, MS E-45, Atlanta, GA 30030, USA, pbk4@cdc.gov Y1 - 2010/03/13/ PY - 2010 DA - 2010 Mar 13 SP - 717 EP - 722 VL - 24 IS - 5 SN - 0269-9370, 0269-9370 KW - Health & Safety Science Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - Acquired immune deficiency syndrome KW - Age KW - CD4 antigen KW - Cell number KW - Drugs KW - Epithelial cells KW - Females KW - Gels KW - Genital microflora KW - Hemoglobin KW - Leukocytes KW - Lymphocytes KW - RNA KW - Sexual behavior KW - Vagina KW - antiretroviral agents KW - antiretroviral therapy KW - flora KW - safety engineering KW - sexual behavior KW - Thailand KW - Human immunodeficiency virus KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/744667802?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS&rft.atitle=HIV+genital+shedding+and+safety+of+Carraguard+use+by+HIV-infected+women%3A+a+crossover+trial+in+Thailand&rft.au=McLean%2C+CA%3Bvan+de+Wijgert%2C+JHHM%3BJones%2C+HE%3BKaron%2C+J+M%3BMcNicoll%2C+J+M%3BWhitehead%2C+S+J%3BBraunstein%2C+S%3BAchalapong%2C+J%3BChaikummao%2C+S%3BTappero%2C+J+W%3BMarkowitz%2C+LE%3BKilmarx%2C+PH&rft.aulast=McLean&rft.aufirst=CA&rft.date=2010-03-13&rft.volume=24&rft.issue=5&rft.spage=717&rft.isbn=&rft.btitle=&rft.title=AIDS&rft.issn=02699370&rft_id=info:doi/10.1097%2FQAD.0b013e328333bf89 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2013-05-06 N1 - SubjectsTermNotLitGenreText - Gels; Hemoglobin; Epithelial cells; Age; CD4 antigen; Cell number; RNA; Leukocytes; antiretroviral therapy; Vagina; Sexual behavior; Genital microflora; sexual behavior; Acquired immune deficiency syndrome; safety engineering; flora; antiretroviral agents; Females; Lymphocytes; Drugs; Human immunodeficiency virus; Thailand DO - http://dx.doi.org/10.1097/QAD.0b013e328333bf89 ER - TY - JOUR T1 - Medical surveillance, exposure registries, and epidemiologic research for workers exposed to nanomaterials AN - 746149843; 12931532 AB - While there is a growing body of information about hazards of nanomaterials, little is known about the risks to workers exposed to them. However, workers are the first people in society that are being exposed to the growing inventory of "nano-enabled" products in commerce. The number of workers involved in the investigation, manufacture, production, and disposal of these types of products is growing. Although toxicologic research is still the highest priority, it is time to actively anticipate the health needs of workers. To date, precautionary risk management approaches have been widely advocated. Now there is a need to initiate an evolving process to identify the issues in medical surveillance, utilization of exposure registries, and the conduct of epidemiologic research. Each of these are related complex endeavors that build on the toxicologic evidence and extent of exposure. There is a need to assess the scientific basis and research needs for determining early functional changes, organ system and disease responses for use in targeted medical surveillance. There is also need for development of criteria for extrapolating toxicological data in biological systems to predict the risk of adverse outcomes in humans. In the meantime, exposure registries may be pivotal in helping societies act in the face of uncertainty in a precautionary manner, but legal, ethical, and logistical issues need resolution. Epidemiologic research will build on these efforts and may ultimately contribute critical definitive rationale for medical screening, risk assessment and management. JF - Toxicology AU - Trout, Douglas B AU - Schulte, Paul A AD - National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, 4676 Columbia Parkway, MS C-14, Cincinnati, OH 45226, USA, PSchulte@cdc.gov Y1 - 2010/03/10/ PY - 2010 DA - 2010 Mar 10 SP - 128 EP - 135 PB - Elsevier Science, P.O. Box 85 Limerick Ireland VL - 269 IS - 2-3 SN - 0300-483X, 0300-483X KW - Health & Safety Science Abstracts; Environment Abstracts; Toxicology Abstracts KW - Risk assessment KW - Inventories KW - Data processing KW - Organs KW - Nanotechnology KW - Risk management KW - Workers KW - Ethics KW - Priorities KW - Occupational exposure KW - nanotechnology KW - H 1000:Occupational Safety and Health KW - X 24300:Methods KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/746149843?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology&rft.atitle=Medical+surveillance%2C+exposure+registries%2C+and+epidemiologic+research+for+workers+exposed+to+nanomaterials&rft.au=Trout%2C+Douglas+B%3BSchulte%2C+Paul+A&rft.aulast=Trout&rft.aufirst=Douglas&rft.date=2010-03-10&rft.volume=269&rft.issue=2-3&rft.spage=128&rft.isbn=&rft.btitle=&rft.title=Toxicology&rft.issn=0300483X&rft_id=info:doi/10.1016%2Fj.tox.2009.12.006 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Number of references - 4 N1 - Last updated - 2015-10-15 N1 - SubjectsTermNotLitGenreText - Risk assessment; Inventories; Workers; Data processing; Ethics; Occupational exposure; nanotechnology; Risk management; Priorities; Organs; Nanotechnology DO - http://dx.doi.org/10.1016/j.tox.2009.12.006 ER - TY - CPAPER T1 - Evaluation of bacterial meningitis Sentinel Surveillance Program (BMSSP) introduce in 2007 in Sao Paulo state, Brazil T2 - 14th International Congress on Infectious Diseases (ICID 2010) AN - 742806952; 5700805 JF - 14th International Congress on Infectious Diseases (ICID 2010) AU - Carvalhanas, T AU - Liphaus, B AU - Pellini, A AU - Yu, A. AU - Freitas, G AU - Ribeiro, A Y1 - 2010/03/09/ PY - 2010 DA - 2010 Mar 09 KW - Brazil KW - Brazil, Sao Paulo KW - Meningitis KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742806952?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=14th+International+Congress+on+Infectious+Diseases+%28ICID+2010%29&rft.atitle=Evaluation+of+bacterial+meningitis+Sentinel+Surveillance+Program+%28BMSSP%29+introduce+in+2007+in+Sao+Paulo+state%2C+Brazil&rft.au=Carvalhanas%2C+T%3BLiphaus%2C+B%3BPellini%2C+A%3BYu%2C+A.%3BFreitas%2C+G%3BRibeiro%2C+A&rft.aulast=Carvalhanas&rft.aufirst=T&rft.date=2010-03-09&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=14th+International+Congress+on+Infectious+Diseases+%28ICID+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://www.x-cd.com/isidmain2010/program.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-17 N1 - Last updated - 2010-08-14 ER - TY - CPAPER T1 - Epidemiological profile of the A (H1N1) pandemic influenza in the state of Sao Paulo, Brazil, for the April-September 2009 timeframe T2 - 14th International Congress on Infectious Diseases (ICID 2010) AN - 742802685; 5700411 JF - 14th International Congress on Infectious Diseases (ICID 2010) AU - Carvalhanas, T AU - Yu, A. AU - Freitas, G AU - Pellini, A AU - Ribeiro, A AU - Liphaus, B Y1 - 2010/03/09/ PY - 2010 DA - 2010 Mar 09 KW - Brazil KW - Brazil, Sao Paulo KW - Influenza KW - Pandemics KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742802685?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=14th+International+Congress+on+Infectious+Diseases+%28ICID+2010%29&rft.atitle=Epidemiological+profile+of+the+A+%28H1N1%29+pandemic+influenza+in+the+state+of+Sao+Paulo%2C+Brazil%2C+for+the+April-September+2009+timeframe&rft.au=Carvalhanas%2C+T%3BYu%2C+A.%3BFreitas%2C+G%3BPellini%2C+A%3BRibeiro%2C+A%3BLiphaus%2C+B&rft.aulast=Carvalhanas&rft.aufirst=T&rft.date=2010-03-09&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=14th+International+Congress+on+Infectious+Diseases+%28ICID+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://www.x-cd.com/isidmain2010/program.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-17 N1 - Last updated - 2010-08-14 ER - TY - JOUR T1 - Safety assessment of recalled Haemophilus influenzae type b (Hib) conjugate vaccines-United States, 2007-2008 AN - 899147165; 15260933 AB - Purpose On 13 December 2007, Merck & Co., Inc. voluntarily recalled 1.2 million doses of Haemophilus influenzae type b (Hib) vaccines that had been distributed since April 2007 for concerns regarding potential Bacillus cereus contamination. Enhanced postrecall surveillance was conducted to detect vaccine-associated B. cereus infections. Methods We reviewed reports involving recalled Hib vaccines received by the Vaccine Adverse Event Reporting System (VAERS) during 1 April 2007-29 February 2008. For each reported death, autopsy review sought evidence of B. cereus infections. For each specified outcome, the proportional reporting ratios (PRRs) were calculated to compare the recalled Hib vaccines with the manufacturer's nonrecalled Hib vaccines in the VAERS databases. On 20 December 2007, we used the Epidemic Information Exchange (Epi-X) to solicit nongastrointestinal vaccine-associated B. cereus infections, and requested B. cereus isolates for genotyping to compare with the manufacturing facility isolate. Results VAERS received 75 reports involving recalled Hib vaccines; none described a confirmed B. cereus infection. Comparative analyses did not reveal disproportionate reporting of specified outcomes for recalled Hib vaccines. The Epi-X posting triggered one report of vaccine-associated B. cereus bacteremia from a child who received a nonrecalled Hib vaccine manufactured by Merck; the genotypes of isolates from the patient and the manufacturing facility differed. Conclusions No evidence of vaccine-associated B. cereus infection had been found in recipients of recalled Hib vaccines. Conducting laboratory surveillance through Epi-X was feasible and may enhance public health response capacities for future vaccine safety emergencies. Published in 2010 by John Wiley & Sons, Ltd. JF - Pharmacoepidemiology and Drug Safety AU - Huang, Wan-Ting AU - Chang, Soju AU - Miller, Elaine R AU - Woo, Emily Jane AU - Hoffmaster, Alex R AU - Gee, Jay E AU - Clark, Thomas A AU - Iskander, John K AU - Ball, Robert AU - Broder, Karen R AD - Epidemic Intelligence Service, Career Development Division, Office of the Workforce and Career Development, Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA, kbroder@cdc.gov Y1 - 2010/03// PY - 2010 DA - Mar 2010 SP - 306 EP - 310 VL - 19 IS - 3 SN - 1053-8569, 1053-8569 KW - Microbiology Abstracts B: Bacteriology KW - Autopsy KW - Haemophilus influenzae KW - Epidemics KW - Contamination KW - Genotyping KW - Bacillus cereus KW - Bacteremia KW - Genotypes KW - Infection KW - Public health KW - Databases KW - Reviews KW - Vaccines KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/899147165?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Pharmacoepidemiology+and+Drug+Safety&rft.atitle=Safety+assessment+of+recalled+Haemophilus+influenzae+type+b+%28Hib%29+conjugate+vaccines-United+States%2C+2007-2008&rft.au=Huang%2C+Wan-Ting%3BChang%2C+Soju%3BMiller%2C+Elaine+R%3BWoo%2C+Emily+Jane%3BHoffmaster%2C+Alex+R%3BGee%2C+Jay+E%3BClark%2C+Thomas+A%3BIskander%2C+John+K%3BBall%2C+Robert%3BBroder%2C+Karen+R&rft.aulast=Huang&rft.aufirst=Wan-Ting&rft.date=2010-03-01&rft.volume=19&rft.issue=3&rft.spage=306&rft.isbn=&rft.btitle=&rft.title=Pharmacoepidemiology+and+Drug+Safety&rft.issn=10538569&rft_id=info:doi/10.1002%2Fpds.1909 L2 - http://onlinelibrary.wiley.com/doi/10.1002/pds.1909/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Databases; Autopsy; Epidemics; Contamination; Genotyping; Reviews; Bacteremia; Genotypes; Vaccines; Infection; Public health; Haemophilus influenzae; Bacillus cereus DO - http://dx.doi.org/10.1002/pds.1909 ER - TY - JOUR T1 - Transcriptional responses to oxidative stress: Pathological and toxicological implications AN - 746080388; 12971435 AB - The utilization of molecular oxygen as the terminal electron acceptor for energy production has in many ways shaped the evolution of complex life, physiology, and certain disease processes. The generation of reactive oxygen species (ROS), either as by-products of O sub(2) metabolism or by specialized enzymes, has the potential to damage cellular components and functions. Exposure to a variety of exogenous toxicants also promotes ROS production directly or through indirect means to cause toxicity. Oxidative stress activates the expression of a wide range of genes that mediate the pathogenic effect of ROS or are required for the detection and detoxification of the oxidants. In many cases, these are mediated by specific transcription factors whose expression, structure, stability, nuclear targeting, or DNA-binding affinity is regulated by the level of oxidative stress. This review examines major transcription factors that mediate transcriptional responses to oxidative stress, focusing on recent progress in the signaling pathways and mechanisms of activation of transcription factors by oxidative stress and the implications of this regulation in the development of disease and chemical toxicity. JF - Pharmacology & Therapeutics AU - Ma, Qiang AD - Receptor Biology Laboratory, Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, United States, qam1@cdc.gov Y1 - 2010/03// PY - 2010 DA - Mar 2010 SP - 376 EP - 393 PB - Elsevier Science, Box 882 New York NY 10159 USA VL - 125 IS - 3 SN - 0163-7258, 0163-7258 KW - Toxicology Abstracts; Biochemistry Abstracts 2: Nucleic Acids KW - Detoxification KW - Oxidative stress KW - N 14835:Protein-Nucleic Acids Association KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/746080388?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Pharmacology+%26+Therapeutics&rft.atitle=Transcriptional+responses+to+oxidative+stress%3A+Pathological+and+toxicological+implications&rft.au=Ma%2C+Qiang&rft.aulast=Ma&rft.aufirst=Qiang&rft.date=2010-03-01&rft.volume=125&rft.issue=3&rft.spage=376&rft.isbn=&rft.btitle=&rft.title=Pharmacology+%26+Therapeutics&rft.issn=01637258&rft_id=info:doi/10.1016%2Fj.pharmthera.2009.11.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Oxidative stress DO - http://dx.doi.org/10.1016/j.pharmthera.2009.11.004 ER - TY - JOUR T1 - Influence of artificial gastric juice composition on bioaccessibility of cobalt- and tungsten-containing powders AN - 746077666; 12972311 AB - The dissolution of metal-containing particles in the gastric compartment is poorly understood. The purpose of this study was to elucidate the influence of artificial gastric juice chemical composition on bioaccessibility of metals associated with ingestion-based health concerns. Dissolution rates were evaluated for well-characterized feedstock cobalt, tungsten metal, and tungsten carbide powders, chemically bonded pre-sintered (spray dryer material) and post-sintered (chamfer grinder) cemented tungsten carbide materials, and an admixture of pure cobalt and pure tungsten carbide, prepared by mechanically blending the two feedstock powders. Dissolution of each study material was evaluated in three different formulations of artificial gastric juice (from simplest to most chemically complex): American Society of Testing Materials (ASTM), U.S. Pharmacopoeia (USP), and National Institute for Occupational Safety and Health (NIOSH). Approximately 20% of cobalt dissolved in the first dissolution phase (t sub(1/2) = 0.02 days) and the remaining 80% was released in the second long-term dissolution phase (t sub(1/2) = 0.5 to 1 days). Artificial gastric juice chemical composition did not influence dissolution rate constant values (k, g/cm super(2) day) of cobalt powder, either alone or as an admixture. Approximately 100% of the tungsten and tungsten carbide that dissolved was released in a single dissolution phase; k-values of each material differed significantly in the solvents: NIOSH > ASTM > USP (p<0.05). The k-values of cobalt and tungsten carbide in pre- and post-sintered cemented tungsten carbide powders were significantly different from values for the pure feedstock powders. Solvent composition had little influence on oral bioaccessibility of highly soluble cobalt and our data support consideration of the oral exposure route as a contributing pathway to total-body exposure. Solvent composition appeared to influence bioaccessibility of the low soluble tungsten compounds, though differences may be due to variability in the data associated with the small masses of materials that dissolved. Nonetheless, ingestion exposure may not contribute appreciably to total body burden given the short residence time of material in the stomach and relatively long dissolution half-times of these materials (t sub(1/2) = 60 to 380 days). JF - International Journal of Hygiene and Environmental Health AU - Stefaniak, Aleksandr B AU - Virji, MAbbas AU - Harvey, Christopher J AU - Sbarra, Deborah C AU - Day, Gregory A AU - Hoover, Mark D AD - National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Mailstop H-2703, Morgantown, WV 26505, USA, astefaniak@cdc.gov Y1 - 2010/03// PY - 2010 DA - Mar 2010 SP - 107 EP - 115 PB - Elsevier GmbH, Office Jena, P.O. Box 100537 Jena D-07705 Germany VL - 213 IS - 2 SN - 1438-4639, 1438-4639 KW - Environment Abstracts KW - Dissolution KW - Gastric juice KW - Ingestion KW - Cobalt KW - Cemented tungsten carbide KW - Metals KW - Chemical composition KW - Tungsten compounds KW - Sprays KW - Solvents KW - Particulates KW - Tungsten KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/746077666?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Hygiene+and+Environmental+Health&rft.atitle=Influence+of+artificial+gastric+juice+composition+on+bioaccessibility+of+cobalt-+and+tungsten-containing+powders&rft.au=Stefaniak%2C+Aleksandr+B%3BVirji%2C+MAbbas%3BHarvey%2C+Christopher+J%3BSbarra%2C+Deborah+C%3BDay%2C+Gregory+A%3BHoover%2C+Mark+D&rft.aulast=Stefaniak&rft.aufirst=Aleksandr&rft.date=2010-03-01&rft.volume=213&rft.issue=2&rft.spage=107&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Hygiene+and+Environmental+Health&rft.issn=14384639&rft_id=info:doi/10.1016%2Fj.ijheh.2009.12.006 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Metals; Chemical composition; Tungsten compounds; Cobalt; Sprays; Solvents; Particulates; Ingestion; Tungsten DO - http://dx.doi.org/10.1016/j.ijheh.2009.12.006 ER - TY - JOUR T1 - Reaching every district (RED) approach to strengthen routine immunization services: evaluation in the African region, 2005? AN - 742722582; 201014277 AB - Background This evaluation was undertaken in 2005, in the African region, to better understand the reaching every district (RED) implementation process that provides a framework for strengthening immunization services at the district level. Methods In June 2005, a convenience sample of five countries was selected to evaluate the implementation of RED. Evaluation teams consisting of key partners conducted site visits to the national, district and health facility levels using standardized qualitative questionnaires. Results RED was implemented in a similar manner in all five countries, i.e. starting with training and micro-planning. All RED components were implemented to some degree in the countries. Common implementation factors included development of plans, expanding outreach services (defined as services provided in sites outside fixed immunization sites), planning of supervisory visits and efforts to link with communities and utilize community volunteers. Monitoring tools such as wall charts and maps were observed and reportedly used. Conclusions Evaluation of the RED implementation process provided evidence of improvement in delivery of routine immunization services. The RED framework should continue to be used to strengthen the immunization delivery system to meet continuing new demands, such as the introduction of new vaccines and integrated delivery of other child survival interventions. Adapted from the source document. JF - Journal of Public Health AU - Ryman, T AU - Macauley, R AU - Nshimirimana, D AU - Taylor, P AU - Shimp, L AU - Wilkins, K AD - Global Immunization Division, National Center for Immunization and Respiratory Diseases, US Centers for Disease Control and Prevention, 1600 Clifton Road, MS-E05, Atlanta, GA 30333, USA Y1 - 2010/03// PY - 2010 DA - March 2010 SP - 18 EP - 25 PB - Oxford University Press VL - 32 IS - 1 SN - 1741-3842, 1741-3842 KW - health services, immunization KW - Walls KW - Vaccines KW - Maps KW - Site visits KW - Service provision KW - Immunization KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742722582?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Public+Health&rft.atitle=Reaching+every+district+%28RED%29+approach+to+strengthen+routine+immunization+services%3A+evaluation+in+the+African+region%2C+2005%3F&rft.au=Ryman%2C+T%3BMacauley%2C+R%3BNshimirimana%2C+D%3BTaylor%2C+P%3BShimp%2C+L%3BWilkins%2C+K&rft.aulast=Ryman&rft.aufirst=T&rft.date=2010-03-01&rft.volume=32&rft.issue=1&rft.spage=18&rft.isbn=&rft.btitle=&rft.title=Journal+of+Public+Health&rft.issn=17413842&rft_id=info:doi/10.1093%2Fpubmed%2Ffdp048 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-06-07 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Immunization; Maps; Walls; Service provision; Vaccines; Site visits DO - http://dx.doi.org/10.1093/pubmed/fdp048 ER - TY - JOUR T1 - Competence as a Predictor of Sexual and Reproductive Health Outcomes for Youth: A Systematic Review AN - 742719170; 201010284 AB - To examine the association between 'competence' and adolescent sexual and reproductive health (ASRH) outcomes. Competence refers to the development of skills to perform tasks successfully in four areas including social and behavioral, cognitive, emotional, and moral competence. We conducted a systematic review of research published from 1985 through 2007. Inclusion criteria included use of multivariate analyses, a sample size of >=100, publication in a peer-reviewed journal, and measurement of an ASRH outcome. We coded findings as protective, risk, or no association and as longitudinal or cross-sectional. We considered the presence of two longitudinal studies with consistent findings for at least one outcome to be sufficient evidence for a risk or protective association. We identified 77 studies that examined cognitive competence, 27 studies that examined social and behavioral competence, 12 studies that examined emotional competence, and no studies that met inclusion criteria for moral competence. The evidence indicated that cognitive competence and social and behavioral competence can be protective factors for ASRH, with findings from at least two longitudinal studies demonstrating a protective association with an ASRH outcome. Findings across cognitive, social and behavioral subconstructs and ASRH outcomes were more mixed. There was insufficient evidence to draw conclusions about emotional and moral competence and ASRH. Helping adolescents to achieve cognitive, social, and behavioral competence may reduce the likelihood of sexual activity and teen pregnancy, and increase contraceptive use. Additional research is needed to examine other outcomes and the generalizability of findings. [Copyright The Society for Adolescent Medicine; published by Elsevier Inc.] JF - Journal of Adolescent Health AU - House, Lawrence Duane AU - Bates, Jessica AU - Markham, Christine M AU - Lesesne, Catherine AD - Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia Lhouse1@cdc.gov Y1 - 2010/03// PY - 2010 DA - March 2010 SP - S7 EP - S22 PB - Elsevier, New York NY VL - 46 IS - 3S1 SN - 1054-139X, 1054-139X KW - Competence Adolescent Sexual behavior Reproductive health KW - Protective factors KW - Competence KW - Social competence KW - Reproductive health KW - Moral aspects KW - Adolescents KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742719170?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Adolescent+Health&rft.atitle=Competence+as+a+Predictor+of+Sexual+and+Reproductive+Health+Outcomes+for+Youth%3A+A+Systematic+Review&rft.au=House%2C+Lawrence+Duane%3BBates%2C+Jessica%3BMarkham%2C+Christine+M%3BLesesne%2C+Catherine&rft.aulast=House&rft.aufirst=Lawrence&rft.date=2010-03-01&rft.volume=46&rft.issue=3S1&rft.spage=S7&rft.isbn=&rft.btitle=&rft.title=Journal+of+Adolescent+Health&rft.issn=1054139X&rft_id=info:doi/10.1016%2Fj.jadohealth.2009.12.003 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-05-10 N1 - Last updated - 2016-09-27 N1 - CODEN - JAHCD9 N1 - SubjectsTermNotLitGenreText - Competence; Social competence; Moral aspects; Adolescents; Protective factors; Reproductive health DO - http://dx.doi.org/10.1016/j.jadohealth.2009.12.003 ER - TY - JOUR T1 - Character as a Predictor of Reproductive Health Outcomes for Youth: A Systematic Review AN - 742717365; 201010285 AB - To review research examining the influence of character on adolescent sexual and reproductive health (ASRH). We defined character as comprising two positive youth development constructs: prosocial norms and spirituality. We conducted a systematic review of behavioral research published from 1985 through 2007 that examined the association between two character constructs (prosocial norms and spirituality) and ASRH outcomes. We coded results as showing a protective association, risk association, or no association, and as longitudinal, or cross-sectional. We considered consistent associations from at least two longitudinal studies for a given outcome to be sufficient evidence for a protective or risk association. There is sufficient evidence to indicate that prosocial norms and spirituality can be protective factors for some ASRH outcomes including intention to have sex, early sex or ever having sex, contraceptive and condom use, frequency of sex, and pregnancy. The generalizability of findings by age, race/ethnicity, and gender was unclear. Findings suggest that some character sub-constructs are associated with a reduced likelihood of several adverse ASRH outcomes and with an increased likelihood of using contraceptives and intending to use condoms. Further research is needed to better understand mixed results and results showing some character sub-constructs, such as religious affiliation, to be associated with adverse ASRH outcomes. [Copyright The Society for Adolescent Medicine; published by Elsevier Inc.] JF - Journal of Adolescent Health AU - House, Lawrence Duane AU - Mueller, Trisha AU - Reininger, Belinda AU - Brown, Kathryn AU - Markham, Christine M AD - Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia Lhouse1@cdc.gov Y1 - 2010/03// PY - 2010 DA - March 2010 SP - S59 EP - S74 PB - Elsevier, New York NY VL - 46 IS - 3S1 SN - 1054-139X, 1054-139X KW - Character Adolescent Sexual behavior Reproductive health KW - Condoms KW - Prosocial behaviour KW - Protective factors KW - Spirituality KW - Personality KW - Reproductive health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742717365?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Adolescent+Health&rft.atitle=Character+as+a+Predictor+of+Reproductive+Health+Outcomes+for+Youth%3A+A+Systematic+Review&rft.au=House%2C+Lawrence+Duane%3BMueller%2C+Trisha%3BReininger%2C+Belinda%3BBrown%2C+Kathryn%3BMarkham%2C+Christine+M&rft.aulast=House&rft.aufirst=Lawrence&rft.date=2010-03-01&rft.volume=46&rft.issue=3S1&rft.spage=S59&rft.isbn=&rft.btitle=&rft.title=Journal+of+Adolescent+Health&rft.issn=1054139X&rft_id=info:doi/10.1016%2Fj.jadohealth.2009.11.218 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-05-10 N1 - Last updated - 2016-09-27 N1 - CODEN - JAHCD9 N1 - SubjectsTermNotLitGenreText - Personality; Prosocial behaviour; Spirituality; Condoms; Reproductive health; Protective factors DO - http://dx.doi.org/10.1016/j.jadohealth.2009.11.218 ER - TY - JOUR T1 - Nanoparticle emission assessment technique (NEAT) for the identification and measurement of potential inhalation exposure to engineered nanomaterials--part A. AN - 733622369; 20017054 AB - There are currently no exposure limits specific to engineered nanomaterial nor any national or international consensus standards on measurement techniques for nanomaterials in the workplace. However, facilities engaged in the production and use of engineered nanomaterials have expressed an interest in learning whether the potential for worker exposure exists. To assist with answering this question, the National Institute for Occupational Safety and Health established a nanotechnology field research team whose primary goal was to visit facilities and evaluate the potential for release of nanomaterials and worker exposure. The team identified numerous techniques to measure airborne nanomaterials with respect to particle size, mass, surface area, number concentration, and composition. However, some of these techniques lack specificity and field portability and are difficult to use and expensive when applied to routine exposure assessment. This article describes the nanoparticle emission assessment technique (NEAT) that uses a combination of measurement techniques and instruments to assess potential inhalation exposures in facilities that handle or produce engineered nanomaterials. The NEAT utilizes portable direct-reading instrumentation supplemented by a pair of filter-based air samples (source-specific and personal breathing zone). The use of the filter-based samples are crucial for identification purposes because particle counters are generally insensitive to particle source or composition and make it difficult to differentiate between incidental and process-related nanomaterials using number concentration alone. Results from using the NEAT at 12 facilities are presented in the companion article (Part B) in this issue. JF - Journal of occupational and environmental hygiene AU - Methner, M AU - Hodson, L AU - Geraci, C AD - National Institute for Occupational Safety and Health, Nanotechnology Research Center, 4676 Columbia Parkway, Cincinnati, OH 45226, USA. MMethner@cdc.gov Y1 - 2010/03// PY - 2010 DA - March 2010 SP - 127 EP - 132 VL - 7 IS - 3 KW - Air Pollutants KW - 0 KW - Index Medicus KW - Workplace KW - Inhalation Exposure -- analysis KW - Nanoparticles -- analysis KW - Air Pollutants -- analysis KW - Occupational Exposure -- analysis KW - Environmental Monitoring -- methods KW - Air Pollutants -- chemistry KW - Nanoparticles -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733622369?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+occupational+and+environmental+hygiene&rft.atitle=Nanoparticle+emission+assessment+technique+%28NEAT%29+for+the+identification+and+measurement+of+potential+inhalation+exposure+to+engineered+nanomaterials--part+A.&rft.au=Methner%2C+M%3BHodson%2C+L%3BGeraci%2C+C&rft.aulast=Methner&rft.aufirst=M&rft.date=2010-03-01&rft.volume=7&rft.issue=3&rft.spage=127&rft.isbn=&rft.btitle=&rft.title=Journal+of+occupational+and+environmental+hygiene&rft.issn=1545-9632&rft_id=info:doi/10.1080%2F15459620903476355 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-03-02 N1 - Date created - 2009-12-17 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1080/15459620903476355 ER - TY - JOUR T1 - Evidence of Selective Sweeps in Genes Conferring Resistance to Chloroquine and Pyrimethamine in Plasmodium falciparum Isolates in India , AN - 21499283; 12495836 AB - Treatment of Plasmodium falciparum is complicated by the emergence and spread of parasite resistance to many of the first-line drugs used to treat malaria. Antimalarial drug resistance has been associated with specific point mutations in several genes, suggesting that these single nucleotide polymorphisms can be useful in tracking the emergence of drug resistance. In India, P. falciparum infection can manifest itself as asymptomatic, mild, or severe malaria, with or without cerebral involvement. We tested whether chloroquine- and antifolate drug-resistant genotypes would be more commonly associated with cases of cerebral malaria than with cases of mild malaria in the province of Jabalpur, India, by genotyping the dhps, dhfr, pfmdr-1, and pfcrt genes using pyrosequencing, direct sequencing, and real-time PCR. Further, we used microsatellites surrounding the genes to determine the origins and spread of the drug-resistant genotypes in this area. Resistance to chloroquine was essentially fixed, with 95% of the isolates harboring the pfcrt K76T mutation. Resistant genotypes of dhfr, dhps, and pfmdr-1 were found in 94%, 17%, and 77% of the isolates, respectively. Drug-resistant genotypes were equally likely to be associated with cerebral malaria as with mild malaria. We found evidence of a selective sweep in pfcrt and, to a lesser degree, in dhfr, indicating high levels of resistance to chloroquine and evolving resistance to pyrimethamine. Microsatellites surrounding pfcrt indicate that the resistant genotypes (SVMNT) were most similar to those found in Papua New Guinea. JF - Antimicrobial Agents & Chemotherapy AU - Mixson-Hayden, Tonya AU - Jain, Vidhan AU - McCollum, Andrea M AU - Poe, Amanda AU - Nagpal, Avinash C AU - Dash, Aditya P AU - Stiles, Jonathan K AU - Udhayakumar, Venkatachalam AU - Singh, Neeru AD - Malaria Branch, Division of Parasitic Diseases, Centers for Disease Control and Prevention, zdy0@cdc.gov Y1 - 2010/03// PY - 2010 DA - Mar 2010 SP - 997 EP - 1006 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 54 IS - 3 SN - 0066-4804, 0066-4804 KW - Genetics Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Pyrimethamine KW - Parasites KW - Human diseases KW - Nucleotide sequence KW - Drug resistance KW - Malaria KW - Genotypes KW - Infection KW - India KW - Public health KW - India, Madhya Pradesh, Jabalpur KW - Dihydrofolate reductase KW - Papua New Guinea KW - Polymerase chain reaction KW - Mutations KW - Genotyping KW - Point mutation KW - Microsatellites KW - Chloroquine KW - Plasmodium falciparum KW - Parasite resistance KW - Single-nucleotide polymorphism KW - DNA KW - A 01340:Antibiotics & Antimicrobials KW - G 07880:Human Genetics KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms KW - K 03310:Genetics & Taxonomy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21499283?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Evidence+of+Selective+Sweeps+in+Genes+Conferring+Resistance+to+Chloroquine+and+Pyrimethamine+in+Plasmodium+falciparum+Isolates+in+India+%2C&rft.au=Mixson-Hayden%2C+Tonya%3BJain%2C+Vidhan%3BMcCollum%2C+Andrea+M%3BPoe%2C+Amanda%3BNagpal%2C+Avinash+C%3BDash%2C+Aditya+P%3BStiles%2C+Jonathan+K%3BUdhayakumar%2C+Venkatachalam%3BSingh%2C+Neeru&rft.aulast=Mixson-Hayden&rft.aufirst=Tonya&rft.date=2010-03-01&rft.volume=54&rft.issue=3&rft.spage=997&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.00846-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2015-10-28 N1 - SubjectsTermNotLitGenreText - Parasites; Human diseases; Mutations; Drug resistance; Nucleotide sequence; DNA; Malaria; Genotypes; Public health; Pyrimethamine; Dihydrofolate reductase; Single-nucleotide polymorphism; Genotyping; Point mutation; Microsatellites; Polymerase chain reaction; Chloroquine; Infection; Parasite resistance; Plasmodium falciparum; India, Madhya Pradesh, Jabalpur; Papua New Guinea; India DO - http://dx.doi.org/10.1128/AAC.00846-09 ER - TY - JOUR T1 - Association of chest radiographic abnormalities with tuberculosis disease in asymptomatic HIV-infected adults AN - 21492929; 12491525 AB - SETTING: Francistown and Gaborone, Botswana. OBJECTIVE: Chest radiography is used to screen for tuberculosis (TB) in asymptomatic persons living with the human immunodeficiency virus (PLWH) seeking isoniazid preventive therapy (IPT). We describe radiographic features in PLWH in a TB-endemic setting and identify features associated with TB disease. DESIGN: Asymptomatic PLWH seeking IPT under program conditions for a clinical trial between 2004 and 2006 received chest radiographs (CXRs) that were read using the standardized Chest Radiograph Reading and Recording System (CRRS). Clinical characteristics, including TB disease, were compared with the radiographic findings. RESULTS: From 2732 screening CXRs, 183 had one or more abnormalities and were scored using CRRS, with 42% having infiltrates (36% upper lobes), 35% paren-chymal fibrosis and 32% adenopathy. TB disease status was determined in 129 (70%) PLWH, of whom 22 (17%) had TB disease. TB disease was associated with upper lobe infiltrates (relative risk [RR] 3.0, 95%CI 1.5-6.2) and mediastinal adenopathy (RR 3.9, 95%CI 1.8-8.4). The sensitivity and specificity of either upper lobe infiltrates or mediastinal lymphadenopathy for TB disease were respectively 64% and 82%. CONCLUSION: A combination of CXR features was useful for predicting TB disease in asymptomatic PLWH. CRRS should be used more frequently in similar studies. JF - International Journal of Tuberculosis and Lung Disease AU - Agizew, T AU - Bachhuber, MA AU - Nyirenda, S AU - Makwaruzi, VZSAM AU - Tedla, Z AU - Tallaksen, R J AU - Parker, JE AU - Mboya, J J AU - Samandari, T AD - Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, 1600 Clifton Rd N E, Mailstop E-10, Atlanta, GA 30333, USA, tsamandari@cdc.gov Y1 - 2010/03// PY - 2010 DA - Mar 2010 SP - 324 EP - 331 PB - International Union Against Tuberculosis and Lung Disease VL - 14 IS - 3 SN - 1027-3719, 1027-3719 KW - Risk Abstracts; Virology & AIDS Abstracts; Microbiology Abstracts B: Bacteriology KW - Risk assessment KW - Sensitivity KW - Mycobacterium KW - Fibrosis KW - Lung diseases KW - clinical trials KW - Chest KW - Clinical trials KW - tuberculosis KW - Lymphadenopathy KW - Human immunodeficiency virus KW - Lung KW - Botswana KW - Standards KW - Tuberculosis KW - Language KW - Radiography KW - Isoniazid KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21492929?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Association+of+chest+radiographic+abnormalities+with+tuberculosis+disease+in+asymptomatic+HIV-infected+adults&rft.au=Agizew%2C+T%3BBachhuber%2C+MA%3BNyirenda%2C+S%3BMakwaruzi%2C+VZSAM%3BTedla%2C+Z%3BTallaksen%2C+R+J%3BParker%2C+JE%3BMboya%2C+J+J%3BSamandari%2C+T&rft.aulast=Agizew&rft.aufirst=T&rft.date=2010-03-01&rft.volume=14&rft.issue=3&rft.spage=324&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Risk assessment; Lymphadenopathy; Fibrosis; Lung diseases; Language; Tuberculosis; Radiography; Chest; Clinical trials; Isoniazid; tuberculosis; Sensitivity; Lung; Standards; clinical trials; Mycobacterium; Human immunodeficiency virus; Botswana ER - TY - JOUR T1 - Adverse events related to multidrug-resistant tuberculosis treatment, Latvia, 2000-2004 AN - 21488594; 12491518 AB - SETTING: Latvia has one of the highest rates of multi-drag-resistant tuberculosis (MDR-TB) globally. Clinical management of MDR-TB requires lengthy multidrug regimens that often cause adverse events. DESIGN: We retrospectively reviewed records of patients who began MDR-TB treatment between 2000 and 2004. Treatment-related adverse events and factors associated with experiencing adverse events were evaluated. We also examined the frequency of and reasons for changing drug regimens. RESULTS: Among 1027 cases, 807 (79%) experienced at least one adverse event, with a median of three events per case. The most commonly reported events were nausea (58%), vomiting (39%) and abdominal pain (24%). More serious events, such as psychiatric episodes (13%), hepatitis (9%) and renal failure (4%), were relatively frequent. A change in drug dose due to an adverse event occurred in 201 (20%) cases, while 661 (64%) had at least one drug discontinued temporarily or permanently. Being older, female, having bilateral lung cavities and a greater number of TB symptoms at baseline were associated with an increased number of events. CONCLUSION: Adverse events were prevalent among MDR-TB cases treated in Latvia, with over two thirds requiring discontinuation of at least one drug. MDR-TB patients who are female, older or have severe TB disease should be closely monitored for treatment-related adverse events. JF - International Journal of Tuberculosis and Lung Disease AU - Bloss, E AU - Kuksa, L AU - Holtz, TH AU - Riekstina, V AU - Skripconoka, V AU - Kammerer, S AU - Leimane, V AD - Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, 1600 Clifton Road, MS E-10, Atlanta, GA 30333, USA, dpu2@cdc.gov Y1 - 2010/03// PY - 2010 DA - Mar 2010 SP - 275 EP - 281 PB - International Union Against Tuberculosis and Lung Disease VL - 14 IS - 3 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology KW - Hepatitis KW - Cavities KW - Vomiting KW - Mycobacterium KW - Drug resistance KW - Lung diseases KW - Renal failure KW - Tuberculosis KW - Nausea KW - Pain KW - Drugs KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21488594?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Adverse+events+related+to+multidrug-resistant+tuberculosis+treatment%2C+Latvia%2C+2000-2004&rft.au=Bloss%2C+E%3BKuksa%2C+L%3BHoltz%2C+TH%3BRiekstina%2C+V%3BSkripconoka%2C+V%3BKammerer%2C+S%3BLeimane%2C+V&rft.aulast=Bloss&rft.aufirst=E&rft.date=2010-03-01&rft.volume=14&rft.issue=3&rft.spage=275&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Hepatitis; Cavities; Vomiting; Drug resistance; Lung diseases; Renal failure; Pain; Nausea; Tuberculosis; Drugs; Mycobacterium ER - TY - CPAPER T1 - Medical Complications Among Ischemic Stroke Hospitalizations in the United States: 1999-2006 T2 - 2010 International Stroke Conference AN - 742803879; 5683483 JF - 2010 International Stroke Conference AU - Tong, Xin AU - Kuklina, Elena AU - George, Mary Y1 - 2010/02/24/ PY - 2010 DA - 2010 Feb 24 KW - USA KW - Complications KW - Stroke KW - Ischemia KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742803879?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2010+International+Stroke+Conference&rft.atitle=Medical+Complications+Among+Ischemic+Stroke+Hospitalizations+in+the+United+States%3A+1999-2006&rft.au=Tong%2C+Xin%3BKuklina%2C+Elena%3BGeorge%2C+Mary&rft.aulast=Tong&rft.aufirst=Xin&rft.date=2010-02-24&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2010+International+Stroke+Conference&rft.issn=&rft_id=info:doi/ L2 - http://strokeconference.americanheart.org/portal/strokeconference/sc/s LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-17 N1 - Last updated - 2010-08-14 ER - TY - CPAPER T1 - Mismatch Amplification Mutation Assays for Genotyping Rickettsia typhi T2 - 8th ASM Biodefense and Emerging Diseases Research Meeting AN - 42343641; 5658637 JF - 8th ASM Biodefense and Emerging Diseases Research Meeting AU - Kato, C Y AU - Munk, A C AU - Robinson, L K AU - Chung, I H AU - Detter, J C AU - Eremeeva, M E AU - Brettin, T S AU - Bruce, D C AU - Dasch, G A Y1 - 2010/02/21/ PY - 2010 DA - 2010 Feb 21 KW - Mutation KW - Genotyping KW - Rickettsia typhi KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42343641?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=8th+ASM+Biodefense+and+Emerging+Diseases+Research+Meeting&rft.atitle=Mismatch+Amplification+Mutation+Assays+for+Genotyping+Rickettsia+typhi&rft.au=Kato%2C+C+Y%3BMunk%2C+A+C%3BRobinson%2C+L+K%3BChung%2C+I+H%3BDetter%2C+J+C%3BEremeeva%2C+M+E%3BBrettin%2C+T+S%3BBruce%2C+D+C%3BDasch%2C+G+A&rft.aulast=Kato&rft.aufirst=C&rft.date=2010-02-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=8th+ASM+Biodefense+and+Emerging+Diseases+Research+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.asmbiodefense.org/images/stories/scientific_section_proof_3 .pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A Rapid Antimicrobial Susceptibility Test for Yersinia pestis T2 - 8th ASM Biodefense and Emerging Diseases Research Meeting AN - 42342730; 5658636 JF - 8th ASM Biodefense and Emerging Diseases Research Meeting AU - Michel, P A AU - Sue, D AU - Pillai, S P AU - Weigel, L M Y1 - 2010/02/21/ PY - 2010 DA - 2010 Feb 21 KW - Antimicrobial agents KW - Yersinia pestis KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42342730?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=8th+ASM+Biodefense+and+Emerging+Diseases+Research+Meeting&rft.atitle=A+Rapid+Antimicrobial+Susceptibility+Test+for+Yersinia+pestis&rft.au=Michel%2C+P+A%3BSue%2C+D%3BPillai%2C+S+P%3BWeigel%2C+L+M&rft.aulast=Michel&rft.aufirst=P&rft.date=2010-02-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=8th+ASM+Biodefense+and+Emerging+Diseases+Research+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.asmbiodefense.org/images/stories/scientific_section_proof_3 .pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Humoral Antibody and Immune Cell Responses to Reduced Schedules of Anthrax Vaccine Adsorbed in Humans T2 - 8th ASM Biodefense and Emerging Diseases Research Meeting AN - 42342503; 5658550 JF - 8th ASM Biodefense and Emerging Diseases Research Meeting AU - Quinn, C P Y1 - 2010/02/21/ PY - 2010 DA - 2010 Feb 21 KW - Anthrax KW - Vaccines KW - Antibodies KW - Disease control KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42342503?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=8th+ASM+Biodefense+and+Emerging+Diseases+Research+Meeting&rft.atitle=Humoral+Antibody+and+Immune+Cell+Responses+to+Reduced+Schedules+of+Anthrax+Vaccine+Adsorbed+in+Humans&rft.au=Quinn%2C+C+P&rft.aulast=Quinn&rft.aufirst=C&rft.date=2010-02-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=8th+ASM+Biodefense+and+Emerging+Diseases+Research+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.asmbiodefense.org/images/stories/scientific_section_proof_3 .pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Detection and Subtyping of Residual C. botulinum DNA in Botulinum Toxin Preparations T2 - 8th ASM Biodefense and Emerging Diseases Research Meeting AN - 42340721; 5658528 JF - 8th ASM Biodefense and Emerging Diseases Research Meeting AU - Joseph, L A AU - Maslanka, S E AU - Raphael, B H Y1 - 2010/02/21/ PY - 2010 DA - 2010 Feb 21 KW - Toxins KW - Botulinum toxin KW - Clostridium botulinum KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42340721?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=8th+ASM+Biodefense+and+Emerging+Diseases+Research+Meeting&rft.atitle=Detection+and+Subtyping+of+Residual+C.+botulinum+DNA+in+Botulinum+Toxin+Preparations&rft.au=Joseph%2C+L+A%3BMaslanka%2C+S+E%3BRaphael%2C+B+H&rft.aulast=Joseph&rft.aufirst=L&rft.date=2010-02-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=8th+ASM+Biodefense+and+Emerging+Diseases+Research+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.asmbiodefense.org/images/stories/scientific_section_proof_3 .pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Storage Effects on Sample Integrity of Environmental Surface Sampling of Specimens with Bacillus anthracis, Primary and Secondary Containment T2 - 8th ASM Biodefense and Emerging Diseases Research Meeting AN - 42340641; 5658513 JF - 8th ASM Biodefense and Emerging Diseases Research Meeting AU - Perry, A AU - O'connell, H AU - Rose, L AU - Noble-Wang, J Y1 - 2010/02/21/ PY - 2010 DA - 2010 Feb 21 KW - Containment KW - Storage KW - Sampling KW - Environmental factors KW - Bacillus anthracis KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42340641?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=8th+ASM+Biodefense+and+Emerging+Diseases+Research+Meeting&rft.atitle=Storage+Effects+on+Sample+Integrity+of+Environmental+Surface+Sampling+of+Specimens+with+Bacillus+anthracis%2C+Primary+and+Secondary+Containment&rft.au=Perry%2C+A%3BO%27connell%2C+H%3BRose%2C+L%3BNoble-Wang%2C+J&rft.aulast=Perry&rft.aufirst=A&rft.date=2010-02-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=8th+ASM+Biodefense+and+Emerging+Diseases+Research+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.asmbiodefense.org/images/stories/scientific_section_proof_3 .pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Survival and Persistence of Non-Spore Forming Biothreat Agents in Water T2 - 8th ASM Biodefense and Emerging Diseases Research Meeting AN - 42339815; 5658632 JF - 8th ASM Biodefense and Emerging Diseases Research Meeting AU - Gilbert, S E AU - Rose, L J AU - Noble-Wang, J Y1 - 2010/02/21/ PY - 2010 DA - 2010 Feb 21 KW - Survival KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42339815?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=8th+ASM+Biodefense+and+Emerging+Diseases+Research+Meeting&rft.atitle=Survival+and+Persistence+of+Non-Spore+Forming+Biothreat+Agents+in+Water&rft.au=Gilbert%2C+S+E%3BRose%2C+L+J%3BNoble-Wang%2C+J&rft.aulast=Gilbert&rft.aufirst=S&rft.date=2010-02-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=8th+ASM+Biodefense+and+Emerging+Diseases+Research+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.asmbiodefense.org/images/stories/scientific_section_proof_3 .pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Recent Multistate Outbreaks of Human Salmonella Infections Acquired from Turtles: A Continuing Public Health Challenge AN - 754544920; 13269616 AB - The federal ban in the United States on the sale of turtles with shell lengths <4 Inches that was established in 1975 has reduced the number of turtle-associated human Salmonella infections during subsequent years, especially among children. Although numerous sporadic turtle-associated Salmonella infections in humans have been reported since the ban went Into effect, outbreaks were not reported until recently. Since 2006, 3 multistate outbreaks of turtle-associated Salmonella infections have been documented in the United States. This review examines the history of turtle-associated human Salmonella infections in the United States and discusses reasons why an increase in turtle-associated salmonellosis may be occurring and how challenges in enforcement of the ban affect disease control. Additional steps should be considered by the public health community, state governments, and enforcement agencies to prevent turtle-associated Salmonella infections in humans. JF - Clinical Infectious Diseases AU - Harris, J R AU - Neil, K P AU - Behravesh, C B AU - Sotir, MJ AU - Angulo, F J AD - 1600 Clifton Rd NE, MS C-09, Atlanta, GA 30309, USA, ggt5@cdc.gov A2 - Angulo, FJ (ed) Y1 - 2010/02/15/ PY - 2010 DA - 2010 Feb 15 SP - 554 EP - 559 VL - 50 IS - 4 SN - 1058-4838, 1058-4838 KW - Health & Safety Science Abstracts; Microbiology Abstracts B: Bacteriology KW - Historical account KW - Disease control KW - disease control KW - Infection KW - Public health KW - infection KW - turtles KW - outbreaks KW - Children KW - USA KW - Reviews KW - Salmonellosis KW - Shells KW - Salmonella KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754544920?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+Infectious+Diseases&rft.atitle=Recent+Multistate+Outbreaks+of+Human+Salmonella+Infections+Acquired+from+Turtles%3A+A+Continuing+Public+Health+Challenge&rft.au=Harris%2C+J+R%3BNeil%2C+K+P%3BBehravesh%2C+C+B%3BSotir%2C+MJ%3BAngulo%2C+F+J&rft.aulast=Harris&rft.aufirst=J&rft.date=2010-02-15&rft.volume=50&rft.issue=4&rft.spage=554&rft.isbn=&rft.btitle=&rft.title=Clinical+Infectious+Diseases&rft.issn=10584838&rft_id=info:doi/10.1086%2F649932 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Salmonellosis; Disease control; Shells; Children; Infection; Public health; Historical account; Reviews; infection; turtles; outbreaks; disease control; Salmonella; USA DO - http://dx.doi.org/10.1086/649932 ER - TY - JOUR T1 - Blood gene expression markers to detect and distinguish target organ toxicity AN - 856759265; 13838966 AB - The purpose of this study was to investigate whether the expression of specific genes in peripheral blood can be used as surrogate marker(s) to detect and distinguish target organ toxicity induced by chemicals in rats. Rats were intraperitoneally administered a single, acute dose of a well-established hepatotoxic (acetaminophen) or a neurotoxic (methyl parathion) chemical. Administration of acetaminophen (AP) in the rats resulted in hepatotoxicity as evidenced from elevated blood transaminase activities. Similarly, administration of methyl parathion (MP) resulted in neurotoxicity in the rats as evidenced from the inhibition of acetyl cholinesterase activity in their blood. Administration of either chemical also resulted in mild hematotoxicity in the rats. Microarray analysis of the global gene expression profile of rat blood identified distinct gene expression markers capable of detecting and distinguishing hepatotoxicity and neurotoxicity induced by AP and MP, respectively. Differential expressions of the marker genes for hepatotoxicity and neurotoxicity were detectable in the blood earlier than the appearance of the commonly used clinical markers (serum transaminases and acetyl cholinesterase). The ability of the marker genes to detect hepatotoxicity and neurotoxicity was further confirmed using the blood samples of rats administered additional hepatotoxic (thioacetamide, dimethylnitrobenzene, and carbon tetrachloride) or neurotoxic (ethyl parathion and malathion) chemicals. In summary, our results demonstrated that blood gene expression markers can detect and distinguish target organ toxicity non-invasively. JF - Molecular and Cellular Biochemistry AU - Umbright, Christina AU - Sellamuthu, Rajendran AU - Li, Shengqiao AU - Kashon, Michael AU - Luster, Michael AU - Joseph, Pius AD - Toxicology and Molecular Biology Branch, National Institute for Occupational Safety and Health, Morgantown, WV, USA, pjoseph1@cdc.gov Y1 - 2010/02// PY - 2010 DA - Feb 2010 SP - 223 EP - 234 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 335 IS - 1-2 SN - 0300-8177, 0300-8177 KW - Toxicology Abstracts; Genetics Abstracts KW - Peripheral blood KW - Cholinesterase KW - hepatotoxicity KW - transaminase KW - Malathion KW - Thioacetamide KW - Gene expression KW - Carbon tetrachloride KW - Neurotoxicity KW - Methyl parathion KW - Acetaminophen KW - Parathion KW - G 07870:Mammals KW - X 24330:Agrochemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/856759265?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Molecular+and+Cellular+Biochemistry&rft.atitle=Blood+gene+expression+markers+to+detect+and+distinguish+target+organ+toxicity&rft.au=Umbright%2C+Christina%3BSellamuthu%2C+Rajendran%3BLi%2C+Shengqiao%3BKashon%2C+Michael%3BLuster%2C+Michael%3BJoseph%2C+Pius&rft.aulast=Umbright&rft.aufirst=Christina&rft.date=2010-02-01&rft.volume=335&rft.issue=1-2&rft.spage=223&rft.isbn=&rft.btitle=&rft.title=Molecular+and+Cellular+Biochemistry&rft.issn=03008177&rft_id=info:doi/10.1007%2Fs11010-009-0272-5 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-03-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Gene expression; Carbon tetrachloride; Neurotoxicity; Peripheral blood; Methyl parathion; Cholinesterase; Thioacetamide; Malathion; transaminase; Acetaminophen; hepatotoxicity; Parathion DO - http://dx.doi.org/10.1007/s11010-009-0272-5 ER - TY - JOUR T1 - Determination of 43 polycyclic aromatic hydrocarbons in air particulate matter by use of direct elution and isotope dilution gas chromatography/mass spectrometry AN - 753693954; 13324407 AB - We are reporting a method for measuring 43 polycyclic aromatic hydrocarbons (PAH) and their methylated derivatives (Me-PAHs) in air particulate matter (PM) samples using isotope dilution gas chromatography/high-resolution mass spectrometry (GC/HRMS). In this method, PM samples were spiked with internal standards, loaded into solid phase extraction cartridges, and eluted by dichloromethane. The extracts were concentrated, spiked with a recovery standard, and analyzed by GC/HRMS at 10,000 resolution. Sixteen C-labeled PAHs and two deuterated Me-PAHs were used as internal standards to account for instrument variability and losses during sample preparation. Recovery of labeled internal standards was in the range of 86--115%. The proposed method is less time-consuming than commonly used extraction methods, such as sonication and accelerated solvent extraction (ASE), and it eliminates the need for a filtration step required after the sonication extraction method. Limits of detection ranged from 41 to 332 pg/sample for the 43 analytes. This method was used to analyze reference materials from the National Institute of Standards and Technology. The results were consistent with those from ASE and sonication extraction, and these results were also in good agreement with the certified or reference concentrations. The proposed method was then used to measure PAHs on PM2.5 samples collected at three sites (urban, suburban, and rural) in Atlanta, GA. The results showed distinct seasonal and spatial variation and were consistent with an earlier study measuring PM2.5 samples using an ASE method, further demonstrating the compatibility of this method and the commonly used ASE method. JF - Analytical and Bioanalytical Chemistry AU - Li, Zheng AU - Pittman, Erin N AU - Trinidad, Debra A AU - Romanoff, Lovisa C AU - Mulholland, James AU - Sjodin, Andreas AD - Centers for Disease Control and Prevention, 4770 Buford Highway F-53, Atlanta, GA 30341, USA, ZJLi@cdc.gov PY - 2010 SP - 1321 EP - 1330 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 396 IS - 3 SN - 1618-2642, 1618-2642 KW - Aqualine Abstracts; Water Resources Abstracts KW - Mass Spectrometry KW - Polycyclic aromatic hydrocarbons KW - Variability KW - Gas Chromatography KW - Sample Preparation KW - Analytical Methods KW - Particulate Matter KW - Wastewater Disposal KW - USA, Georgia, Atlanta KW - Standards KW - AQ 00001:Water Resources and Supplies KW - SW 5040:Data acquisition UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/753693954?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytical+and+Bioanalytical+Chemistry&rft.atitle=Determination+of+43+polycyclic+aromatic+hydrocarbons+in+air+particulate+matter+by+use+of+direct+elution+and+isotope+dilution+gas+chromatography%2Fmass+spectrometry&rft.au=Li%2C+Zheng%3BPittman%2C+Erin+N%3BTrinidad%2C+Debra+A%3BRomanoff%2C+Lovisa+C%3BMulholland%2C+James%3BSjodin%2C+Andreas&rft.aulast=Li&rft.aufirst=Zheng&rft.date=2010-02-01&rft.volume=396&rft.issue=3&rft.spage=1321&rft.isbn=&rft.btitle=&rft.title=Analytical+and+Bioanalytical+Chemistry&rft.issn=16182642&rft_id=info:doi/10.1007%2Fs00216-009-3297-4 L2 - http://www.springerlink.com/content/q0161t003213p826/?p=cc8f9f1377b646ce9dc2c414a268de00&pi=36 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-12-01 N1 - Last updated - 2016-01-21 N1 - SubjectsTermNotLitGenreText - Sample Preparation; Mass Spectrometry; Variability; Polycyclic aromatic hydrocarbons; Analytical Methods; Particulate Matter; Wastewater Disposal; Standards; Gas Chromatography; USA, Georgia, Atlanta DO - http://dx.doi.org/10.1007/s00216-009-3297-4 ER - TY - JOUR T1 - The national study to prevent blood exposure in paramedics: rates of exposure to blood AN - 746082466; 12597881 AB - Objective: The purpose of this analysis is to present incidence rates of exposure to blood among paramedics in the United States by selected variables and to compare all percutaneous exposure rates among different types of healthcare workers. Methods: A survey on blood exposure was mailed in 2002-2003 to a national sample of paramedics. Results for California paramedics were analyzed with the national sample and also separately. Results: The incidence rate for needlestick/lancet injuries was 100/1,000 employee-years [95% confidence interval (CI), 40-159] among the national sample and 26/1,000 employee-years (95% CI, 15-38) for the California sample. The highest exposure rate was for non-intact skin, 230/1,000 employee-years (95% CI, 130-329). The rate for all exposures was 465/1,000 employee-years (95% CI, 293-637). California needlestick/lancet rates, but not national, were substantially lower than rates in earlier studies of paramedics. Rates for all percutaneous injuries among paramedics were similar to the mid to high range of rates reported for most hospital-based healthcare workers. Conclusions: Paramedics in the United States are experiencing percutaneous injury rates at least as high as, and possibly substantially higher than, most hospital-based healthcare workers, as well as substantially higher rates of exposure to blood on non-intact skin. JF - International Archives of Occupational and Environmental Health AU - Boal, Winifred L AU - Leiss, Jack K AU - Ratcliffe, Jennifer M AU - Sousa, Sara AU - Lyden, Jennifer T AU - Li, Jia AU - Jagger, Janine AD - National Institute for Occupational Safety and Health (NIOSH), Cincinnati, OH, USA, wboal@cdc.gov Y1 - 2010/02// PY - 2010 DA - Feb 2010 SP - 191 EP - 199 PB - Springer-Verlag, Heidelberger Platz 3 Berlin 14197 Germany VL - 83 IS - 2 SN - 0340-0131, 0340-0131 KW - Health & Safety Science Abstracts; Water Resources Abstracts KW - Blood KW - Skin KW - Injuries KW - Exposure KW - Surveys KW - USA, California KW - Medical personnel KW - SW 3030:Effects of pollution KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/746082466?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Archives+of+Occupational+and+Environmental+Health&rft.atitle=The+national+study+to+prevent+blood+exposure+in+paramedics%3A+rates+of+exposure+to+blood&rft.au=Boal%2C+Winifred+L%3BLeiss%2C+Jack+K%3BRatcliffe%2C+Jennifer+M%3BSousa%2C+Sara%3BLyden%2C+Jennifer+T%3BLi%2C+Jia%3BJagger%2C+Janine&rft.aulast=Boal&rft.aufirst=Winifred&rft.date=2010-02-01&rft.volume=83&rft.issue=2&rft.spage=191&rft.isbn=&rft.btitle=&rft.title=International+Archives+of+Occupational+and+Environmental+Health&rft.issn=03400131&rft_id=info:doi/10.1007%2Fs00420-009-0421-x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Skin; Injuries; Medical personnel; Blood; Exposure; Surveys; USA, California DO - http://dx.doi.org/10.1007/s00420-009-0421-x ER - TY - JOUR T1 - Translating questionnaire items for a multi-lingual worker population: The iterative process of translation and cognitive interviews with English-, Spanish-, and Chinese-speaking workers AN - 745630712; 12739898 AB - Background The increasing ethnic diversity of the US workforce has created a need for research tools that can be used with multi-lingual worker populations. Developing multi-language questionnaire items is a complex process; however, very little has been documented in the literature. Methods Commonly used English items from the Job Content Questionnaire and Quality of Work Life Questionnaire were translated by two interdisciplinary bilingual teams and cognitively tested in interviews with English-, Spanish-, and Chinese-speaking workers. Results Common problems across languages mainly concerned response format. Language-specific problems required more conceptual than literal translations. Some items were better understood by non-English speakers than by English speakers. De-centering (i.e., modifying the English original to correspond with translation) produced better understanding for one item. Conclusions Translating questionnaire items and achieving equivalence across languages require various kinds of expertise. Backward translation itself is not sufficient. More research efforts should be concentrated on qualitative approaches to developing useful research tools. Am. J. Ind. Med. 53:194-203 2010. Published 2009 Wiley-Liss, Inc. JF - American Journal of Industrial Medicine AU - Fujishiro, Kaori AU - Gong, Fang AU - Baron, Sherry AU - Jacobson Jr, C Jeffery AU - Delaney, Sheli AU - Flynn, Michael AU - Eggerth, Donald E AD - Division of Surveillance, Hazard Evaluation, and Field Studies, National Institute for Occupational Safety and Health, Cincinnati, Ohio, kfujishiro@cdc.gov Y1 - 2010/02// PY - 2010 DA - Feb 2010 SP - 194 EP - 203 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 USA VL - 53 IS - 2 SN - 0271-3586, 0271-3586 KW - Health & Safety Science Abstracts KW - Communications KW - Perception KW - Cognitive ability KW - Occupational safety KW - Ethnic groups KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745630712?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Translating+questionnaire+items+for+a+multi-lingual+worker+population%3A+The+iterative+process+of+translation+and+cognitive+interviews+with+English-%2C+Spanish-%2C+and+Chinese-speaking+workers&rft.au=Fujishiro%2C+Kaori%3BGong%2C+Fang%3BBaron%2C+Sherry%3BJacobson+Jr%2C+C+Jeffery%3BDelaney%2C+Sheli%3BFlynn%2C+Michael%3BEggerth%2C+Donald+E&rft.aulast=Fujishiro&rft.aufirst=Kaori&rft.date=2010-02-01&rft.volume=53&rft.issue=2&rft.spage=194&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=02713586&rft_id=info:doi/10.1002%2Fajim.20733 L2 - http://www3.interscience.wiley.com/journal/122528202/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Communications; Cognitive ability; Perception; Occupational safety; Ethnic groups DO - http://dx.doi.org/10.1002/ajim.20733 ER - TY - JOUR T1 - Using surveillance data to promote occupational health and safety policies and practice at the state level: A case study AN - 745630704; 12739897 AB - Background Following the investigation of a birth defects cluster involving migrant farmworkers employed in North Carolina and Florida, it became clear that greater efforts were needed to protect agricultural workers from pesticide exposure. Methods Documentation is drawn from peer-reviewed published articles, government reports and news accounts. Results The birth defects cluster was identified and investigated by state and federal pesticide poisoning surveillance system staff. Following the investigation, efforts were initiated to highlight pesticides as an important public health issue needing more attention. A series of subsequent events led to the creation and passage of important legislation recently enacted in North Carolina. The legislation resulted in funding to promote various activities to prevent harm from pesticides including strengthening surveillance, improving the quality of pesticide compliance inspections, and increasing and improving pesticide safety training. The legislation also broadened the coverage of anti-retaliation rules to include agricultural workers, and increased recordkeeping requirements pertaining to pesticide applications. Conclusion The important and positive impacts that can occur through surveillance activities are highlighted. As such, it is important to continue to support and improve occupational illness and injury surveillance programs. Am. J. Ind. Med. 53:188-193 2010. Published 2009 Wiley-Liss, Inc. JF - American Journal of Industrial Medicine AU - Calvert, Geoffrey M AU - Higgins, Sheila A AD - Division of Surveillance, Hazard Evaluations, and Field Studies, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, Ohio, jac6@cdc.gov Y1 - 2010/02// PY - 2010 DA - Feb 2010 SP - 188 EP - 193 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 USA VL - 53 IS - 2 SN - 0271-3586, 0271-3586 KW - Health & Safety Science Abstracts KW - USA, North Carolina KW - USA, Florida KW - Injuries KW - Training KW - Migrant workers KW - Compliance KW - Poisoning KW - inspection KW - Public health KW - case studies KW - Pesticides KW - Congenital defects KW - Occupational exposure KW - Legislation KW - Occupational health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745630704?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Using+surveillance+data+to+promote+occupational+health+and+safety+policies+and+practice+at+the+state+level%3A+A+case+study&rft.au=Calvert%2C+Geoffrey+M%3BHiggins%2C+Sheila+A&rft.aulast=Calvert&rft.aufirst=Geoffrey&rft.date=2010-02-01&rft.volume=53&rft.issue=2&rft.spage=188&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=02713586&rft_id=info:doi/10.1002%2Fajim.20707 L2 - http://www3.interscience.wiley.com/journal/122408525/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Injuries; Training; Migrant workers; Compliance; Poisoning; inspection; Public health; case studies; Pesticides; Congenital defects; Legislation; Occupational exposure; Occupational health; USA, North Carolina; USA, Florida DO - http://dx.doi.org/10.1002/ajim.20707 ER - TY - JOUR T1 - Surveillance of occupational health disparities: Challenges and opportunities AN - 745630678; 12739886 AB - Increasingly, the occupational health community is turning its attention to the effects of work on previously underserved populations, and researchers have identified many examples of disparities in occupational health outcomes. However, the occupational health status of some underserved worker populations is not described due to limitations in existing surveillance systems. As such, the occupational health community has identified the need to enhance and improve occupational health surveillance to describe the nature and extent of disparities in occupational illnesses and injuries (including fatalities), identify priorities for research and intervention, and evaluate trends. This report summarizes the data sources and methods discussed at an April 2008 workshop organized by NIOSH on the topic of improving surveillance for occupational health disparities. We discuss the capability of existing occupational health surveillance systems to document occupational health disparities and to provide surveillance data on minority and other underserved communities. Use of administrative data, secondary data analysis, and the development of targeted surveillance systems for occupational health surveillance are also discussed. Identifying and reducing occupational health disparities is one of NIOSH's priority areas under the National Occupational Research Agenda (NORA). Am. J. Ind. Med. 53:84-94 2010. Published 2010 Wiley-Liss, Inc. JF - American Journal of Industrial Medicine AU - Souza, Kerry AU - Steege, Andrea L AU - Baron, Sherry L AD - Division of Surveillance, Hazard Evaluations and Field Studies (DSHEFS), National Institute for Occupational Safety and Health (NIOSH), US Centers for Disease Control and Prevention (CDC), Washington, District of Columbia, ksouza@cdc.gov Y1 - 2010/02// PY - 2010 DA - Feb 2010 SP - 84 EP - 94 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 USA VL - 53 IS - 2 SN - 0271-3586, 0271-3586 KW - Health & Safety Science Abstracts KW - Mortality KW - Injuries KW - intervention KW - Occupational health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745630678?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Surveillance+of+occupational+health+disparities%3A+Challenges+and+opportunities&rft.au=Souza%2C+Kerry%3BSteege%2C+Andrea+L%3BBaron%2C+Sherry+L&rft.aulast=Souza&rft.aufirst=Kerry&rft.date=2010-02-01&rft.volume=53&rft.issue=2&rft.spage=84&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=02713586&rft_id=info:doi/10.1002%2Fajim.20777 L2 - http://www3.interscience.wiley.com/journal/123248908/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Mortality; Injuries; intervention; Occupational health DO - http://dx.doi.org/10.1002/ajim.20777 ER - TY - JOUR T1 - Dogs and cats as environmental fall hazards AN - 744613246; 12981178 AB - Problem - Falls are the leading cause of non-fatal injuries in the United States. This study assessed the prevalence of fall injuries associated with cats and dogs in the United States and describes the types of injuries sustained, the location, activity, and circumstances under which they occurred. Methods - Data were from a nationally representative sample of emergency department visits from January 1, 2001 to December 31, 2006, available through the National Electronic Injury Surveillance System All Injury Program (NEISS-AIP). Results - Based on 7,456 cases, an estimated 86,629 fall injuries each year were associated with cats and dogs, for an injury rate of 29.7. There were 7.5 times as many injuries involving dogs as cats and females were 2.1 times more likely to be injured than males. Injury rates were highest among people aged >= 75, but pets were a fall hazard for all ages. Fractures and contusions or abrasions were the most common injuries; the highest rates were for injuries to the extremities. About 66.4% of falls associated with cats and 31.3 % of falls associated with dogs were caused by falling or tripping over the pet. An additional 21.2% of falls related to dogs were caused by being pushed or pulled. Summary - Although pets were associated with fall injuries, this risk can be reduced by increasing public awareness about situations that can lead to falls, such as dog-walking and chasing pets, and by calling attention to the importance of obedience training for dogs to minimize hazardous behaviors such as pulling and pushing. Impact on industry - Fall injuries represent a burden to individuals, our society and our health care system. Increasing public awareness and implementing basic prevention strategies can help people of all ages enjoy their pets, reduce their chances of experiencing pet-related falls, and lessen the impact of fall injuries on our health care system. JF - Journal of Safety Research AU - Stevens, Judy A AU - Teh, S L AU - Haileyesus, Tadesse AD - Division of Unintentional Injury Prevention, National Center for Injury Prevention and Control, 4770 Buford Highway NE, MS F-62, Atlanta, GA 30341 USA The Journal of Safety Research has partnered with the Office of the Associate Director for Science, Division of Unintentional Injury Prevention at the Centers for Disease Control and Prevention (CDC) in Atlanta, Georgia, USA, to briefly report on some of the latest findings in the research community. This report is the 17th in a series of CDC articles.. Available online 28 January 2010., jas2@cdc.gov Y1 - 2010/02// PY - 2010 DA - Feb 2010 SP - 69 EP - 73 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK VL - 41 IS - 1 SN - 0022-4375, 0022-4375 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Age KW - Falls KW - Injuries KW - public awareness KW - Training KW - extremities KW - Hazards KW - USA KW - Health care KW - pets KW - prevention KW - emergency medical services KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/744613246?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Safety+Research&rft.atitle=Dogs+and+cats+as+environmental+fall+hazards&rft.au=Stevens%2C+Judy+A%3BTeh%2C+S+L%3BHaileyesus%2C+Tadesse&rft.aulast=Stevens&rft.aufirst=Judy&rft.date=2010-02-01&rft.volume=41&rft.issue=1&rft.spage=69&rft.isbn=&rft.btitle=&rft.title=Journal+of+Safety+Research&rft.issn=00224375&rft_id=info:doi/10.1016%2Fj.jsr.2010.01.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2011-12-15 N1 - SubjectsTermNotLitGenreText - Hazards; Age; Health care; Injuries; Falls; Training; public awareness; pets; prevention; extremities; emergency medical services; USA DO - http://dx.doi.org/10.1016/j.jsr.2010.01.001 ER - TY - JOUR T1 - Ocular and Respiratory Symptoms Among Lifeguards at a Hotel Indoor Waterpark Resort AN - 744590388; 12580687 AB - Objectives: To determine the cause of eye and respiratory irritation symptoms among lifeguards at an indoor waterpark. Methods: Investigators 1) performed environmental sampling for chloramine, endotoxin, and microbials; 2) administered symptom questionnaires; 3) reviewed ventilation system designs; and 4) reviewed water chemistry. Results: Airborne trichloramine concentrations were found at levels reported to cause irritation symptoms in other studies. Some endotoxin concentrations were found at levels associated with cough and fever in previous studies. Exposed lifeguards were significantly more likely to report work-related irritation symptoms than unexposed individuals. The ventilation system may not have provided sufficient air movement and distribution to adequately capture and remove air contaminants at deck level. No water microbes were detected, and water chemistry met state standards. Conclusions: Indoor waterparks need to control water chemistry and ensure adequate air movement and distribution to control air contaminants and reduce health symptoms. JF - Journal of Occupational and Environmental Medicine AU - Dang, B AU - Chen, L AU - Mueller, C AU - Dunn, KH AU - Almaguer, D AU - Roberts, J L AU - Otto, C S AD - Centers for Disease Control and Prevention/National Institute for Occupational Safety and Health (CDC/NIOSH), 4676 Columbia Parkway, MS-R11, Cincinnati, OH 45226, USA, Lchen4@cdc.gov Y1 - 2010/02// PY - 2010 DA - Feb 2010 SP - 207 EP - 213 VL - 52 IS - 2 SN - 1076-2752, 1076-2752 KW - Pollution Abstracts; Health & Safety Science Abstracts KW - Endotoxins KW - Environmental monitoring KW - Ventilation KW - Eye KW - water chemistry KW - hotels KW - Air pollution KW - Recreation areas KW - Reviews KW - Occupational exposure KW - H 1000:Occupational Safety and Health KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/744590388?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Ocular+and+Respiratory+Symptoms+Among+Lifeguards+at+a+Hotel+Indoor+Waterpark+Resort&rft.au=Dang%2C+B%3BChen%2C+L%3BMueller%2C+C%3BDunn%2C+KH%3BAlmaguer%2C+D%3BRoberts%2C+J+L%3BOtto%2C+C+S&rft.aulast=Dang&rft.aufirst=B&rft.date=2010-02-01&rft.volume=52&rft.issue=2&rft.spage=207&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e3181cf00d5 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Environmental monitoring; Air pollution; Endotoxins; Eye; Ventilation; Recreation areas; Reviews; water chemistry; Occupational exposure; hotels DO - http://dx.doi.org/10.1097/JOM.0b013e3181cf00d5 ER - TY - JOUR T1 - Development of a personal dual-phase air sampling method for phthalate diesters AN - 21290612; 12536880 AB - Phthalates are used as plasticizers in many industrial and consumer products. Urinary biomonitoring has shown widespread human exposure to phthalates, with workers having especially high exposures. Phthalates can be present in workplace air as either aerosols or vapors depending on source materials, vapor pressure, and processing temperatures. We sought to develop a dual-phase air sampling method for 6 phthalates, dimethyl phthalate (DMP), diethyl phthalate (DEP), di-n-butyl phthalate (DBP), benzyl butyl phthalate (BzBP), di(2-ethylhexyl) phthalate (DEHP), and di-n-octyl phthalate (DnOP), adaptable to aerosol inlets with known particle collection characteristics. Collection media consisted of a quartz fiber filter and XAD-2 resin. Limit of detection (LOD) and limit of quantification (LOQ) were determined for each phthalate. Phthalate recoveries were evaluated at 3x, lOx and 30x the LOQ, and after storage at --21 C and 21 C. Media were Soxhlet extracted in 10% diethyl ether in hexanes along with an extraction surrogate, di-n-pentyl phthalate-d sub(4). Gas chromatography/mass spectrometry was performed to quantify the phthalate diesters using di(2-ethylhexyl) phthalate-d sub(4) as an internal standard. Estimated LODs were 1 kg per sample (BzBP, DEHP, and DnOP), 2 kg per sample (DMP and DBP), and 5 kg per sample (DEP). Mean recoveries under static conditions were 85-104% for DBP, BzBP, DEHP, and DnOP; but <70% for DMP and DEP at 3x and 10x the LOQ. After air was pulled through spiked samples, DMP and DEP recoveries improved to 74-81%. After storage for 62 days, phthalate recovery was better at -21 C than at 21 C. Method accuracy was best for DBP, BzBP, DEHP, and DnOP (range 11-18%), and less so for DMP (28%) and DEP (29%). JF - Journal of Environmental Monitoring AU - Hines, C J AU - Yau, A Y AU - Zuniga, M M AU - Wells, J R AU - Hopf, NBN AU - Camann, DE AD - National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, 4776 Columbia Pkwy, R-14, Cincinnati, OH, 45226, USA, chines@cdc.gov Y1 - 2010/02// PY - 2010 DA - Feb 2010 SP - 491 EP - 499 VL - 12 IS - 2 SN - 1464-0325, 1464-0325 KW - Health & Safety Science Abstracts; Environment Abstracts; Pollution Abstracts KW - Bioindicators KW - Aerosols KW - Resins KW - Consumer products KW - Temperature KW - Mass spectrometry KW - Particulates KW - Storage KW - Filters KW - vapor pressure KW - phthalates KW - Vapors KW - Urine KW - Gas chromatography KW - Phthalates KW - Air sampling KW - Ethers KW - Occupational exposure KW - Vapor pressure KW - H 1000:Occupational Safety and Health KW - P 6000:TOXICOLOGY AND HEALTH KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21290612?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+Monitoring&rft.atitle=Development+of+a+personal+dual-phase+air+sampling+method+for+phthalate+diesters&rft.au=Hines%2C+C+J%3BYau%2C+A+Y%3BZuniga%2C+M+M%3BWells%2C+J+R%3BHopf%2C+NBN%3BCamann%2C+DE&rft.aulast=Hines&rft.aufirst=C&rft.date=2010-02-01&rft.volume=12&rft.issue=2&rft.spage=491&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+Monitoring&rft.issn=14640325&rft_id=info:doi/10.1039%2Fb913700a LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2013-06-28 N1 - SubjectsTermNotLitGenreText - Bioindicators; Resins; Aerosols; Consumer products; Temperature; Mass spectrometry; Particulates; Filters; Storage; phthalates; vapor pressure; Vapors; Phthalates; Gas chromatography; Urine; Air sampling; Ethers; Vapor pressure; Occupational exposure DO - http://dx.doi.org/10.1039/b913700a ER - TY - JOUR T1 - Oral pre-exposure prophylaxis for HIV prevention AN - 1837324781; 15370825 AB - In the absence of an effective vaccine, HIV continues to spread worldwide, emphasizing the need for new biomedical interventions to limit its transmission. Appreciation of the challenges that HIV has to face to initiate an infection mucosally has spurred interest in evaluating the use of antiretroviral drugs to prevent infection. Recent animal studies using macaques or humanized mice models of mucosal transmission of SIV or HIV have shown that daily or intermittent pre-exposure prophylaxis (PrEP) with tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC) can exploit early virus vulnerabilities and effectively prevent establishment of infection. These preclinical findings have fueled interest in evaluating the safety and efficacy of PrEP in humans. We provide an overview of the rationale behind PrEP and discuss the next steps in PrEP research, including the need to better define the ability of current drugs to reach and accumulate in mucosal tissues and protect cells that are primary targets during early HIV infection. JF - Trends in Pharmacological Sciences AU - Garcia-Lerma, JGerardo AU - Paxton, Lynn AU - Kilmarx, Peter H AU - Heneine, Walid AD - Division of HIV/AIDS Prevention, National Center for HIV, Hepatitis, STD, and Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30329, USA, GGarcia-Lerma@cdc.gov Y1 - 2010/02// PY - 2010 DA - February 2010 SP - 74 EP - 81 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 31 IS - 2 SN - 0165-6147, 0165-6147 KW - Toxicology Abstracts KW - Macaca KW - Retroviridae KW - Mucosa KW - Animal models KW - tenofovir KW - Infection KW - Lentivirus KW - Antiviral agents KW - Emtricitabine KW - Reviews KW - Prophylaxis KW - Vaccines KW - Drugs KW - X 24310:Pharmaceuticals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1837324781?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Trends+in+Pharmacological+Sciences&rft.atitle=Oral+pre-exposure+prophylaxis+for+HIV+prevention&rft.au=Garcia-Lerma%2C+JGerardo%3BPaxton%2C+Lynn%3BKilmarx%2C+Peter+H%3BHeneine%2C+Walid&rft.aulast=Garcia-Lerma&rft.aufirst=JGerardo&rft.date=2010-02-01&rft.volume=31&rft.issue=2&rft.spage=74&rft.isbn=&rft.btitle=&rft.title=Trends+in+Pharmacological+Sciences&rft.issn=01656147&rft_id=info:doi/10.1016%2Fj.tips.2009.10.009 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-11-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Emtricitabine; Antiviral agents; Reviews; Mucosa; Animal models; Prophylaxis; tenofovir; Vaccines; Infection; Drugs; Lentivirus; Macaca; Retroviridae DO - http://dx.doi.org/10.1016/j.tips.2009.10.009 ER - TY - JOUR T1 - Global Trends in Typhoid and Paratyphoid Fever AN - 754541216; 13265712 AB - Typhoid and paratyphoid fever continue to be important causes of illness and death, particularly among children and adolescents in south-central and Southeast Asia, where enteric fever is associated with poor sanitation and unsafe food and water. High-quality incidence data from Asia are underpinning efforts to expand access to typhoid vaccines. Efforts are underway to develop vaccines that are immunogenic in infants after a single dose and that can be produced locally in countries of endemlcity. The growing importance of Salmonella enterica serotype Paratyphi A in Asia is concerning. Antimicrobial resistance has sequentially emerged to traditional first-line drugs, fluoroqulnolones, and third-generation cephalosporins, posing patient treatment challenges. Azlthromycin has proven to be an effective alternative for treatment of uncomplicated typhoid fever. The availability of full genome sequences for S. enterica serotype Typhi and S. enterica serotype Paratyphi A confirms their place as monomorphlc, human-adapted pathogens vulnerable to control measures if international efforts can be redoubled. JF - Clinical Infectious Diseases AU - Crump, JA AU - Mintz, ED AD - Enteric Diseases Epidemiology Branch, National Center for Zoonotic, Vectorborne, and Enteric Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd, MS A-38, Atlanta, GA 30333, USA, jcrump@cdc.gov Y1 - 2010/01/15/ PY - 2010 DA - 2010 Jan 15 SP - 241 EP - 246 VL - 50 IS - 2 SN - 1058-4838, 1058-4838 KW - Health & Safety Science Abstracts; Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology; Virology & AIDS Abstracts KW - Genomes KW - vaccines KW - Serotypes KW - Drug resistance KW - Food KW - Sanitation KW - Paratyphis KW - Asia KW - Southeast Asia KW - Paratyphoid fever KW - Typhoid fever KW - Drugs KW - Adolescents KW - Mortality KW - Cephalosporins KW - Data processing KW - Adolescence KW - Pathogens KW - Children KW - Immunogenicity KW - Salmonella enterica KW - vulnerability KW - Vaccines KW - antimicrobial agents KW - Infants KW - V 22350:Immunology KW - A 01330:Food Microbiology KW - J 02350:Immunology KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754541216?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Human+Resource+Development+Quarterly&rft.atitle=Assessing+the+influence+of+managerial+coaching+on+employee+outcomes&rft.au=Kim%2C+Sewon&rft.aulast=Kim&rft.aufirst=Sewon&rft.date=2014-04-01&rft.volume=25&rft.issue=1&rft.spage=59&rft.isbn=&rft.btitle=&rft.title=Human+Resource+Development+Quarterly&rft.issn=10448004&rft_id=info:doi/10.1002%2Fhrdq.21175 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Genomes; Cephalosporins; Serotypes; Data processing; Food; Adolescence; Drug resistance; Pathogens; Children; Sanitation; Immunogenicity; Vaccines; Typhoid fever; Paratyphoid fever; Infants; Mortality; vaccines; vulnerability; Drugs; antimicrobial agents; Adolescents; Paratyphis; Salmonella enterica; Southeast Asia; Asia DO - http://dx.doi.org/10.1086/649541 ER - TY - JOUR T1 - Changes in Neisseria meningitidis Disease Epidemiology in the United States, 1998-2007: Implications for Prevention of Meningococcal Disease AN - 754540743; 13265706 AB - Background. In January 2005, a quadrivalent (serogroups A, C, Y, and W-135) meningococcal conjugate vaccine was licensed for use in adolescents. This report describes the epidemiologlc features of meningococcal disease in the United States from January 1998 through December 2007, before and during implementation of adolescent quadrivalent meningococcal conjugate vaccination. Methods. Data were collected from active surveillance for invasive Neisseria meningitidis conducted through the Active Bacterial Core surveillance (ABCs) sites during 1998-2007. Isolates from cases were serogrouped at the ABCs site and confirmed at the Centers for Disease Control and Prevention. Estimates of the incidence and number of cases in the 50 states were calculated, standardizing for race and age group. Results. In the period 1998-2007, a total of 2262 cases of meningococcal disease were reported from ABCs sites; 11.3% of these cases were fatal. The estimated United States average annual incidence of meningococcal disease was 0.53 cases per 100,000 population (95% confidence interval, 0.51-0.55), and an estimated 1525 (95% confidence interval, 1470-1598) cases occurred annually. The annual incidence decreased 64.1%, from 0.92 cases per 100,000 population in 1998 to 0.33 cases per 100,000 population in 2007. Infants aged <1 year have the highest incidence of meningococcal disease (5.38 cases per 100,000 population). After introduction of the quadrivalent meningococcal conjugate vaccine, no significant decrease in serogroup C or Y meningococcal disease was seen among those aged 11-19 years in 2006-2007, compared with 2004-2005. Conclusions. Before the introduction of the quadrivalent meningococcal conjugate vaccine, the incidence of meningococcal disease in the United States decreased to a historic low. However, meningococcal disease still causes a substantial burden of disease among all age groups. Future vaccination strategies may include targeting infants and preventing serogroup B meningococcal disease. JF - Clinical Infectious Diseases AU - Cohn, A C AU - MacNell, J R AU - Harrison, L H AU - Hatcher, C AU - Theodore, J AU - Schmidt, M AU - Pondo, T AU - Arnold, KE AU - Baumbach, J AU - Bennett, N AU - Craig, A S AU - Farley, M AU - Gershman, K AU - Petit, S AD - National Center for Immunizations and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd, MS C-09, Atlanta, GA 30333, USA, acohn@cdc.gov Y1 - 2010/01/15/ PY - 2010 DA - 2010 Jan 15 SP - 184 EP - 191 VL - 50 IS - 2 SN - 1058-4838, 1058-4838 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology KW - Age KW - Data processing KW - Epidemiology KW - meningococcal disease KW - Adolescence KW - Disease control KW - Neisseria meningitidis KW - Vaccines KW - Vaccination KW - Races KW - Infants KW - A 01380:Plant Protection, Fungicides & Seed Treatments KW - J 02350:Immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754540743?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+Infectious+Diseases&rft.atitle=Changes+in+Neisseria+meningitidis+Disease+Epidemiology+in+the+United+States%2C+1998-2007%3A+Implications+for+Prevention+of+Meningococcal+Disease&rft.au=Cohn%2C+A+C%3BMacNell%2C+J+R%3BHarrison%2C+L+H%3BHatcher%2C+C%3BTheodore%2C+J%3BSchmidt%2C+M%3BPondo%2C+T%3BArnold%2C+KE%3BBaumbach%2C+J%3BBennett%2C+N%3BCraig%2C+A+S%3BFarley%2C+M%3BGershman%2C+K%3BPetit%2C+S&rft.aulast=Cohn&rft.aufirst=A&rft.date=2010-01-15&rft.volume=50&rft.issue=2&rft.spage=184&rft.isbn=&rft.btitle=&rft.title=Clinical+Infectious+Diseases&rft.issn=10584838&rft_id=info:doi/10.1086%2F649209 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Age; Data processing; Epidemiology; meningococcal disease; Adolescence; Disease control; Vaccines; Vaccination; Races; Infants; Neisseria meningitidis DO - http://dx.doi.org/10.1086/649209 ER - TY - JOUR T1 - MCV vaccination in the presence of vaccine-associated Guillain-Barre Syndrome risk: A decision analysis approach AN - 21146684; 11358695 AB - The study evaluates the benefits of meningococcal conjugate vaccine (MCV4) vaccination against the burden of vaccine-associated Guillain-Barre Syndrome (GBS) using simulation. An 11-year-old cohort was followed over an 8-year period in a simulation model Table 3 Fig. 1 and Fig. 2 to estimate health outcomes to assist decision makers in setting policy. Applying a 3% discount rate, MCV4 vaccination would save 2397 quality-adjusted life years (QALYs) while vaccine-attributable GBS could result in 5 QALYs lost. Based on the result, MCV4 vaccination is strongly favored despite possible vaccine-associated GBS risk. JF - Vaccine AU - Cho, Bo-Hyun AU - Clark, Thomas A AU - Messonnier, Nancy E AU - Ortega-Sanchez, Ismael R AU - Weintraub, Eric AU - Messonnier, Mark L AD - McKing Consulting Corporation, 1600 Clifton Rd. NE MS E-52, Atlanta, GA 30333, United States, bcho@cdc.gov Y1 - 2010/01/08/ PY - 2010 DA - 2010 Jan 08 SP - 817 EP - 822 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 28 IS - 3 SN - 0264-410X, 0264-410X KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Decision analysis KW - Meningococcal disease KW - Guillain-Barre Syndrome KW - Quality-adjusted life years KW - Guillain-Barre syndrome KW - Neisseria meningitidis KW - Vaccines KW - Vaccination KW - Models KW - F 06905:Vaccines KW - J 02350:Immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21146684?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=MCV+vaccination+in+the+presence+of+vaccine-associated+Guillain-Barre+Syndrome+risk%3A+A+decision+analysis+approach&rft.au=Cho%2C+Bo-Hyun%3BClark%2C+Thomas+A%3BMessonnier%2C+Nancy+E%3BOrtega-Sanchez%2C+Ismael+R%3BWeintraub%2C+Eric%3BMessonnier%2C+Mark+L&rft.aulast=Cho&rft.aufirst=Bo-Hyun&rft.date=2010-01-08&rft.volume=28&rft.issue=3&rft.spage=817&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/10.1016%2Fj.vaccine.2009.10.050 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-01-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Guillain-Barre syndrome; Vaccines; Vaccination; Models; Neisseria meningitidis DO - http://dx.doi.org/10.1016/j.vaccine.2009.10.050 ER - TY - JOUR T1 - Water Safety Plan demonstration projects in Latin America and the Caribbean: lessons from the field AN - 911155149; 16066923 AB - A Water Safety Plan (WSP) is a preventive, risk management approach to ensure drinking water safety. This emerging methodology is being increasingly applied in both industrialized and lower income countries worldwide. In 2006, the U.S. Centers for Disease Control and Prevention (CDC) and other local, national, and international partners in Latin America and the Caribbean (LAC) initiated a series of WSP demonstration projects. The objectives were to raise WSP awareness, build capacity, and promote adoption of the WSP approach while identifying those factors that aid or hinder water safety planning efforts in resource-challenged settings. This paper presents eleven lessons learned from these WSP demonstration projects, including the importance of assembling a well-supported interagency team, long-term commitment to WSP implementation, adherence to a water quality monitoring plan, and determining how WSP impacts will be evaluated prior to WSP initiation. To assist in supporting future WSP activity in the region, this paper shares experiences that led to these successes, challenges, and lessons learned. JF - Water Science & Technology: Water Supply AU - Rinehold, Angella AU - Corrales, Lana AU - Medlin, Elizabeth AU - Gelting, Richard J AD - Global Water, Sanitation and Hygiene Team, Environmental Health Services Branch, National Center for Environmental Health, United States Centers for Disease Control and Prevention, Department of Health and Human Services, Atlanta, GA, USA, rgelting@cdc.gov Y1 - 2010 PY - 2010 DA - 2010 SP - 297 EP - 308 PB - IWA Publishing, Alliance House London SW1H 0QS United Kingdom VL - 10 IS - 1 SN - 1606-9749, 1606-9749 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Risk Abstracts; Pollution Abstracts; Sustainability Science Abstracts; Water Resources Abstracts; Environment Abstracts; Aqualine Abstracts KW - Pollution monitoring KW - Water Supply KW - Disease control KW - Water quality KW - Water supplies KW - Income KW - ASW, Caribbean Sea KW - Drinking Water KW - Planning KW - Regional planning KW - Latin America KW - Safety KW - Water Quality KW - Water supply KW - Risk KW - Risk management KW - USA KW - Prevention KW - Water management KW - Capacity KW - Monitoring KW - Drinking water KW - National planning KW - AQ 00007:Industrial Effluents KW - P 2000:FRESHWATER POLLUTION KW - M3 1010:Issues in Sustainable Development KW - Q5 08502:Methods and instruments KW - SW 3060:Water treatment and distribution KW - ENA 16:Renewable Resources-Water KW - R2 23070:Economics, organization UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/911155149?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Water+Science+%26+Technology%3A+Water+Supply&rft.atitle=Water+Safety+Plan+demonstration+projects+in+Latin+America+and+the+Caribbean%3A+lessons+from+the+field&rft.au=Rinehold%2C+Angella%3BCorrales%2C+Lana%3BMedlin%2C+Elizabeth%3BGelting%2C+Richard+J&rft.aulast=Rinehold&rft.aufirst=Angella&rft.date=2010-01-01&rft.volume=10&rft.issue=1&rft.spage=297&rft.isbn=&rft.btitle=&rft.title=Water+Science+%26+Technology%3A+Water+Supply&rft.issn=16069749&rft_id=info:doi/10.2166%2Fws.2011.050 L2 - http://www.iwaponline.com/ws/01103/ws011030297.htm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-12-01 N1 - Last updated - 2014-05-02 N1 - SubjectsTermNotLitGenreText - Pollution monitoring; Drinking Water; Water management; Planning; Disease control; Regional planning; Water quality; National planning; Water supply; Risk management; Prevention; Drinking water; Water supplies; Income; Risk; Safety; Water Supply; Water Quality; Capacity; Monitoring; USA; ASW, Caribbean Sea; Latin America DO - http://dx.doi.org/10.2166/ws.2011.050 ER - TY - JOUR T1 - Beyond beta : Lessons Learned from Implementation of the Department of Veterans Affairs Methicillin-Resistant Staphylococcus aureus Prevention Initiative AN - 907161612; 14771399 AB - To describe the key strategies and potential pitfalls involved with implementing the Department of Veterans Affairs (VA) Methicillin-Resistant Staphylococcus aureus (MRSA) Prevention Initiative in a qualitative evaluation, we conducted in-depth interviews with MRSA Prevention Coordinators at 17 VA beta sites at 2 time points during program implementation. JF - Infection Control and Hospital Epidemiology AU - Garcia-Williams, Amanda G AU - Miller, LaToya J AU - Burkitt, Kelly H AU - Cuerdon, Timothy AU - Jain, Rajiv AU - Fine, Michael J AU - Jernigan, John A AU - Sinkowitz-Cochran, Ronda L AD - Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia (A.G.G.-W., J.A.J., R.L.S.-C.), RLS7@cdc.gov Y1 - 2010 PY - 2010 DA - 2010 SP - 763 EP - 765 PB - University of Chicago Press, P.O. Box 37005 Chicago IL 60637 USA VL - 31 IS - 7 SN - 0899-823X, 0899-823X KW - Microbiology Abstracts B: Bacteriology KW - Drug resistance KW - Staphylococcus aureus KW - Hospitals KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/907161612?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Infection+Control+and+Hospital+Epidemiology&rft.atitle=Beyond+beta+%3A+Lessons+Learned+from+Implementation+of+the+Department+of+Veterans+Affairs+Methicillin-Resistant+Staphylococcus+aureus+Prevention+Initiative&rft.au=Garcia-Williams%2C+Amanda+G%3BMiller%2C+LaToya+J%3BBurkitt%2C+Kelly+H%3BCuerdon%2C+Timothy%3BJain%2C+Rajiv%3BFine%2C+Michael+J%3BJernigan%2C+John+A%3BSinkowitz-Cochran%2C+Ronda+L&rft.aulast=Garcia-Williams&rft.aufirst=Amanda&rft.date=2010-01-01&rft.volume=31&rft.issue=7&rft.spage=763&rft.isbn=&rft.btitle=&rft.title=Infection+Control+and+Hospital+Epidemiology&rft.issn=0899823X&rft_id=info:doi/10.1086%2F653818 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Drug resistance; Hospitals; Staphylococcus aureus DO - http://dx.doi.org/10.1086/653818 ER - TY - JOUR T1 - ASSESSMENT OF PHYSICAL ACTIVITY RELATED BEHAVIOUR AMONG THE ADULT POPULATION IN TBILISI, THE CAPITAL OF GEORGIA AN - 902369384; 15891991 AB - Background: Physical inactivity belongs among the leading preventable risk factors linked with premature mortality and the overall disease burden due to NCD in the country of Georgia. PA related behavior was included in the programme of the NCD RF Survey conducted among adults in Tbilisi in 2007 aimed to facilitate the developing of RF surveillance system. Objective: To estimate the prevalence of physical inactivity among adults, we wanted to utilize the information at hand for developing responses to needs, planning future interventions for the strengthened capacity of integrated NCD prevention and control, and establish NCD survey teams, which will be able to provide for surveys in other parts of the country of Georgia apart from Tbilisi and also at the national level. Methods: Physical activity was assessed by asking 2742 respondents aged 25-64 years of both sexes about the time they spent doing different types of activities. We inquired about the frequency of performing different types of physical activity in a typical week, and the time spent doing these activities during the day was also assessed. The domains where physical activity was assessed included: work, travel to and from places (transportation), and recreation. The intensity of physical activity was categorized into vigorous, moderate and low intensity. Results: Despite the fact that 92.6% of the respondents have a number of possibilities to exercise, 93.9% of the survey participants (91% male and 96.7% female) haven't practiced physical activities during the last 7 days, 55.1% of the respondents (59.1% male and 50.5% female) haven't done any moderate physical activities at all, 66.7% have spent more than an hour doing low intensity physical activities, 43.5% of the respondents (49.1% male and 38.2% female) have spent their time sitting for more than 6 hours daily, and 85.6% of those surveyed do any kind of leisure time physical activity (for at least 30 min.) leading to shortness of breath or perspiration only a few times a year or less frequently. At the same time, information for the personnel of primary health care was provided to them through the following brochures - be physically active, achieve and maintain a normal body weight; brochures were prepared (in printed form and as software) for primary health care workers and were disseminated at the health promotion event on Hypertension day. Conclusions: The prevalence of physical inactivity and its determinants are very high. Probably it is one of the main reasons for the NCD burden in Tbilisi. It seems necessary to establish a stepwise surveillance system for what further steps are planned: conducting the survey at the national level; implementing the survey on regular a basis (within 3-5 years); involving all relevant stakeholders; continuous collaboration with WHO and other international organizations. JF - Acta Universitatis Palackianae Olomucensis. Gymnica AU - Beruchashvili, M AU - Baramidze, L AU - Tataradze, R AD - National Center for Disease Control and Public Health, Tbilisi, Georgia, USA Y1 - 2010 PY - 2010 DA - 2010 SP - 64 VL - 40 IS - 3 SN - 1212-1185, 1212-1185 KW - Physical Education Index KW - Health (care) KW - Programs KW - Behavior KW - Team sports KW - Surveys KW - Exercise KW - Adults KW - Diseases KW - Activities KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/902369384?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Acta+Universitatis+Palackianae+Olomucensis.+Gymnica&rft.atitle=ASSESSMENT+OF+PHYSICAL+ACTIVITY+RELATED+BEHAVIOUR+AMONG+THE+ADULT+POPULATION+IN+TBILISI%2C+THE+CAPITAL+OF+GEORGIA&rft.au=Beruchashvili%2C+M%3BBaramidze%2C+L%3BTataradze%2C+R&rft.aulast=Beruchashvili&rft.aufirst=M&rft.date=2010-01-01&rft.volume=40&rft.issue=3&rft.spage=64&rft.isbn=&rft.btitle=&rft.title=Acta+Universitatis+Palackianae+Olomucensis.+Gymnica&rft.issn=12121185&rft_id=info:doi/ LA - English DB - Physical Education Index N1 - Date revised - 2011-11-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Programs; Health (care); Behavior; Team sports; Surveys; Diseases; Adults; Exercise; Activities ER - TY - JOUR T1 - Disclosure of HIV-positive serostatus to sexual partners and associated factors in southern China AN - 864952173; 14048994 AB - In light of an increased push for disclosure of HIV-positive serostatus to sexual partners (partner disclosure, PD) in China as reflected by national and local policies, the objective of this study was to determine the proportion and evaluate associated factors of PD among people living with HIV/AIDS (PLWHA) in HIV/AIDS high-risk areas in southern China. Of the 946 HIV-positive individuals, the proportion of those who disclosed positive serostatus results to their sexual partners was 90.2% (625/693). Variables independently associated with non-disclosure included testing in Guangxi province (adjusted relative ratio [ARR] = 0.33), becoming infected with HIV via injecting drug use (IDU) transmission (ARR = 0.32), having not reported discussing disclosure with health department staff during post-test counselling (ARR = 0.41) and having a sexual relationship of less than or equal to 2 years' duration (ARR = 0.31). This study also identified a relatively larger differential between the proportion of disclosure to regular partners and the proportion of disclosure to casual partners (94.8% versus 13.0%) in comparison with other studies. Findings from this study may aid policies for future consideration. JF - International Journal of STD & AIDS AU - Wang, L AU - Shan, D AU - Chan, S AU - Chen, H AU - Ge, Z AU - Ding, G AU - Zhang, L AU - Duan, S AU - Liu, W AU - Liu, Z AU - Yang, J AU - Chen, Y AU - Chen, X AU - Wang, N AD - National Center for AIDS/STD Control & Prevention, Chinese Center for Disease Control & Prevention, Xuanwu District Y1 - 2010 PY - 2010 DA - 2010 SP - 685 EP - 690 PB - Royal Society of Medicine Press Ltd., 1 Wimpole St. London W1M 8AE UK VL - 21 IS - 10 SN - 0956-4624, 0956-4624 KW - Risk Abstracts; Virology & AIDS Abstracts KW - Sexual partners KW - sexual behavior KW - Acquired immune deficiency syndrome KW - Human immunodeficiency virus KW - China, People's Rep., Guangxi Prov. KW - Risk groups KW - Drug abuse KW - Drugs KW - sexually transmitted diseases KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/864952173?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+STD+%26+AIDS&rft.atitle=Disclosure+of+HIV-positive+serostatus+to+sexual+partners+and+associated+factors+in+southern+China&rft.au=Wang%2C+L%3BShan%2C+D%3BChan%2C+S%3BChen%2C+H%3BGe%2C+Z%3BDing%2C+G%3BZhang%2C+L%3BDuan%2C+S%3BLiu%2C+W%3BLiu%2C+Z%3BYang%2C+J%3BChen%2C+Y%3BChen%2C+X%3BWang%2C+N&rft.aulast=Wang&rft.aufirst=L&rft.date=2010-01-01&rft.volume=21&rft.issue=10&rft.spage=685&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+STD+%26+AIDS&rft.issn=09564624&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-05-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Sexual partners; Acquired immune deficiency syndrome; Risk groups; Drugs; sexual behavior; Human immunodeficiency virus; Drug abuse; sexually transmitted diseases; China, People's Rep., Guangxi Prov. ER - TY - JOUR T1 - Ground Failures in Coal Mines with Weak Roof AN - 862783051; 14543004 AB - Coal miners who work and travel under supported roof expect to be protected from rock falls. However, rock fall accidents and injuries continue to occur in coal mines that have been supported according to the roof control plan. Experience at coal mines with large numbers of falls indicates that many have weak roof. Control of this roof may require additional ground control measures. An understanding of the geologic and stress conditions which lead to roof falls is necessary to assess the risk of failure and to design roof reinforcement to improve stability. Six common roof fall types, with attached field examples, are described. Roof support practices for each fall type are also described. JF - Electronic Journal of Geotechnical Engineering AU - Molinda, G AU - Mark, C AD - National Institute for Occupational Safety and Health (NIOSH) P.O. Box 18070, Cochrans Mill Rd. Pgh, PA 15236, USA, cnm4@cdc.gov Y1 - 2010 PY - 2010 DA - 2010 SP - 547 EP - 588 PB - Electronic Journal of Geotechnical Engineering VL - 15 IS - F SN - 1089-3032, 1089-3032 KW - Health & Safety Science Abstracts KW - Travel KW - Accidents KW - Injuries KW - Occupational safety KW - Stress KW - Geology KW - Coal KW - Mining KW - Mines KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/862783051?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Electronic+Journal+of+Geotechnical+Engineering&rft.atitle=Ground+Failures+in+Coal+Mines+with+Weak+Roof&rft.au=Molinda%2C+G%3BMark%2C+C&rft.aulast=Molinda&rft.aufirst=G&rft.date=2010-01-01&rft.volume=15&rft.issue=F&rft.spage=547&rft.isbn=&rft.btitle=&rft.title=Electronic+Journal+of+Geotechnical+Engineering&rft.issn=10893032&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-04-01 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Travel; Accidents; Injuries; Occupational safety; Stress; Geology; Mining; Coal; Mines ER - TY - JOUR T1 - Sampling Hard-to-Reach Populations with Respondent Driven Sampling AN - 822511573; 201060703 AB - Cost effective and targeted prevention, intervention and treatment programs for hard-to-reach populations at risk for HIV and other infections rely on the collection of quality data through biological and behavioral surveillance surveys (BBSS). Over the past decade, there has been a global expansion of BBSS to measure the prevalence of HIV and other infections, and related risk behaviors among injecting drug users, males who have sex with males, and female sex workers. However, a major challenge to sampling these hard-to-reach populations is that they are usually stigmatised and/or practice illegal behaviors which, in turn, make them difficult to access and unwilling to participate in research efforts. Over the past decade, respondent driven sampling (RDS) has become recognised as a viable option for rigorous sampling of hard-to-reach populations. This paper introduces RDS methods and describes some of the advantages and challenges to implementing and analysing surveys that use RDS. Adapted from the source document. JF - Methodological Innovations Online AU - Johnston, Lisa G AU - Sabin, Keith AD - Dept HIV, World Health Organisation, Geneva, Switzerland Y1 - 2010///0, PY - 2010 DA - 0, 2010 SP - 38 EP - 48 PB - School of Sociology, Politics and Law, University of Plymouth, UK VL - 5 IS - 2 SN - 1748-0612, 1748-0612 KW - Respondent driven sampling, most-at-risk populations, HIV, behavioral surveillance KW - Risk KW - Acquired Immune Deficiency Syndrome KW - Males KW - Respondents KW - Prostitution KW - Sampling KW - article KW - 9043: methodology and research technology; research methods and models UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/822511573?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Methodological+Innovations+Online&rft.atitle=Sampling+Hard-to-Reach+Populations+with+Respondent+Driven+Sampling&rft.au=Johnston%2C+Lisa+G%3BSabin%2C+Keith&rft.aulast=Johnston&rft.aufirst=Lisa&rft.date=2010-01-01&rft.volume=5&rft.issue=2&rft.spage=38&rft.isbn=&rft.btitle=&rft.title=Methodological+Innovations+Online&rft.issn=17480612&rft_id=info:doi/ L2 - http://erdt.plymouth.ac.uk/mionline/public_html/index.php LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2010-12-16 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Sampling; Respondents; Males; Acquired Immune Deficiency Syndrome; Risk; Prostitution ER - TY - JOUR T1 - Increasing Incidence of Post-Kala-Azar Dermal Leishmaniasis in a Population-Based Study in Bangladesh AN - 754546274; 13265395 AB - Post-kala-azar dermal leishmaniasis (PKDL) occurs after kala-azar treatment and acts as a durable infection reservoir. On the basis of active case finding among 22,699 respondents, 813 (3.6%) had had kala-azar since 2002, of whom 79 (9.7%) developed PKDL. Eight additional patients with PKDL had no history of kala-azar. Annual kala-azar incidence peaked at 85 cases per 10,000 person-years in 2004 and fell to 46 cases per 10,000 person-years in 2007, but PKDL incidence rose from 1 case per 10,000 person-years in 2002-2004 to 21 cases per 10,000 person-years in 2007. The rising PKDL incidence threatens the regional visceral leishmaniasis elimination initiative and underscores the urgent need for more effective PKDL diagnosis and treatment. JF - Clinical Infectious Diseases AU - Rahman, K M AU - Islam, S AU - Rahman, M W AU - Kenan, E AU - Galive, C M AU - Zahld, M M AU - Maguire, J AU - Rahman, M AU - Haque, R AU - Luby, S P AU - Bern, C AD - Div of Parasitic Diseases, MS F-22, 4770 Buford Hwy NE, National Center for Zoonotic, Vector-Borne and Enteric Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA, CBern@cdc.gov Y1 - 2010/01/01/ PY - 2010 DA - 2010 Jan 01 SP - 73 EP - 76 VL - 50 IS - 1 SN - 1058-4838, 1058-4838 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Reservoir KW - Skin KW - Infectious diseases KW - Visceral leishmaniasis KW - Disease control KW - Population studies KW - Infection KW - Bangladesh KW - Public health KW - K 03400:Human Diseases KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754546274?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+Infectious+Diseases&rft.atitle=Increasing+Incidence+of+Post-Kala-Azar+Dermal+Leishmaniasis+in+a+Population-Based+Study+in+Bangladesh&rft.au=Rahman%2C+K+M%3BIslam%2C+S%3BRahman%2C+M+W%3BKenan%2C+E%3BGalive%2C+C+M%3BZahld%2C+M+M%3BMaguire%2C+J%3BRahman%2C+M%3BHaque%2C+R%3BLuby%2C+S+P%3BBern%2C+C&rft.aulast=Rahman&rft.aufirst=K&rft.date=2010-01-01&rft.volume=50&rft.issue=1&rft.spage=73&rft.isbn=&rft.btitle=&rft.title=Clinical+Infectious+Diseases&rft.issn=10584838&rft_id=info:doi/10.1086%2F648727 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2016-02-04 N1 - SubjectsTermNotLitGenreText - Reservoir; Infectious diseases; Disease control; Public health; Skin; Visceral leishmaniasis; Population studies; Infection; Bangladesh DO - http://dx.doi.org/10.1086/648727 ER - TY - JOUR T1 - Biofilm formation is not required for early-phase transmission of Yersinia pestis AN - 754535680; 13242621 AB - Early-phase transmission (EPT) is a recently described model of plague transmission that explains the rapid spread of disease from flea to mammal host during an epizootic. Unlike the traditional blockage-dependent model of plague transmission, EPT can occur when a flea takes its first blood meal after initially becoming infected by feeding on a bacteraemic host. Blockage of the flea gut results from biofilm formation in the proventriculus, mediated by the gene products found in the haemin storage (hms) locus of the Yersinia pestis chromosome. Although biofilms are required for blockage-dependent transmission, the role of biofilms in EPT has yet to be determined. An artificial feeding system was used to feed Xenopsylla cheopis and Oropsylla montana rat blood spiked with the parental Y. pestis strain KIM5(pCD1)+, two different biofilm-deficient mutants (hmsT, hmsR), or a biofilm-overproducer mutant (hmsP). Infected fleas were then allowed to feed on naive Swiss Webster mice for 1-4 days after infection, and the mice were monitored for signs of infection. We also determined the bacterial loads of each flea that fed upon naive mice. Biofilm-defective mutants transmitted from X. cheopis and O. montana as efficiently as the parent strain, whereas the EPT efficiency of fleas fed the biofilm-overproducing strain was significantly less than that of fleas fed either the parent or a biofilm-deficient strain. Fleas infected with a biofilm-deficient strain harboured lower bacterial loads 4 days post- infection than fleas infected with the parent strain. Thus, defects in biofilm formation did not prevent flea-borne transmission of Y. pestis in our EPT model, although biofilm overproduction inhibited efficient EPT. Our results also indicate, however, that biofilms may play a role in infection persistence in the flea. JF - Microbiology AU - Vetter, Sara M AU - Eisen, Rebecca J AU - Schotthoefer, Anna M AU - Montenieri, John A AU - Holmes, Jennifer L AU - Bobrov, Alexander G AU - Bearden, Scott W AU - Perry, Robert D AU - Gage, Kenneth L AD - Bacterial Diseases Branch, Division of Vector Borne Diseases, National Center for Enteric and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, 3150 Rampart Rd, Fort Collins, CO 80521, USA, SVetter@cdc.gov Y1 - 2010 PY - 2010 DA - 2010 SP - 2216 EP - 2225 PB - Society for General Microbiology, Marlborough House, Basingstoke Road Spencers Wood Reading RG7 1AG UK, [URL:http://www.sgm.ac.uk/] VL - 156 IS - 7 SN - 1350-0872, 1350-0872 KW - Entomology Abstracts; Microbiology Abstracts B: Bacteriology KW - Feeding KW - Animal models KW - Yersinia pestis KW - Epizootics KW - Blood meals KW - Infection KW - Models KW - Disease transmission KW - Xenopsylla cheopis KW - Blood KW - Chromosomes KW - Digestive tract KW - Biofilms KW - Plague KW - J 02410:Animal Diseases KW - Z 05300:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754535680?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Microbiology&rft.atitle=Biofilm+formation+is+not+required+for+early-phase+transmission+of+Yersinia+pestis&rft.au=Vetter%2C+Sara+M%3BEisen%2C+Rebecca+J%3BSchotthoefer%2C+Anna+M%3BMontenieri%2C+John+A%3BHolmes%2C+Jennifer+L%3BBobrov%2C+Alexander+G%3BBearden%2C+Scott+W%3BPerry%2C+Robert+D%3BGage%2C+Kenneth+L&rft.aulast=Vetter&rft.aufirst=Sara&rft.date=2010-01-01&rft.volume=156&rft.issue=7&rft.spage=2216&rft.isbn=&rft.btitle=&rft.title=Microbiology&rft.issn=13500872&rft_id=info:doi/10.1099%2Fmic.0.037952-0 L2 - http://mic.sgmjournals.org/cgi/reprint/156/7/2216.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Blood; Feeding; Chromosomes; Digestive tract; Animal models; Epizootics; Blood meals; Plague; Biofilms; Infection; Disease transmission; Models; Xenopsylla cheopis; Yersinia pestis DO - http://dx.doi.org/10.1099/mic.0.037952-0 ER - TY - JOUR T1 - Outbreak of Carbapenem-Resistant Klebsiella pneumoniae in Puerto Rico Associated with a Novel Carbapenemase Variant AN - 745978634; 12845266 AB - Background. Carbapenem-resistant Klebsiella pneumoniae (CRKP) is resistant to almost all antimicrobial agents, and CRKP infections are associated with substantial morbidity and mortality. Objective. To describe an outbreak of CRKP in Puerto Rico, determine risk factors for CRKP acquisition, and detail the successful measures taken to control the outbreak. Design. Two case-control studies. Setting. A 328-bed tertiary care teaching hospital. Patients. Twenty-six CRKP case patients identified during the outbreak period of February through September 2008, 26 randomly selected uninfected control patients, and 26 randomly selected control patients with carbapenem-susceptible K. pneumoniae (CSKP) hospitalized during the same period. Methods. We performed active case finding, including retrospective review of the hospital's microbiology database and prospective perirectal surveillance culture sampling in high-risk units. Case patients were compared with each control group while controlling for time at risk. We sequenced the bla sub(KPC) gene with polymerase chain reaction for 7 outbreak isolates and subtyped these isolates with pulsed-field gel electrophoresis. Results. In matched, multivariable analysis, the presence of wounds (hazard ratio, 19.0 [95% confidence interval {CI}, 2.5-142.0]) was associated with CRKP compared with no K. pneumoniae. Transfer between units (adjusted odds ratio [OR], 7.5 [95% CI, 1.8-31.1]), surgery (adjusted OR, 4.0 [95% CI, 1.0-15.7]), and wounds (adjusted OR, 4.9 [95% CI, 1.1-21.8]) were independent risk factors for CRKP compared to CSKP. A novel K. pneumoniae carbapenemase variant (KPC-8) was present in 5 isolates. Implementation of active surveillance for CRKP colonization and cohorting of CRKP patients rapidly controlled the outbreak. Conclusions. Enhanced surveillance for CRKP colonization and intensified infection control measures that include limiting the physical distribution of patients can reduce CRKP transmission during an outbreak. JF - Infection Control and Hospital Epidemiology AU - Gregory, Christopher J AU - Llata, Eloisa AU - Stine, Nicholas AU - Gould, Carolyn AU - Santiago, Luis Manuel AU - Vazquez, Guillermo J AU - Robledo, Iraida E AU - Srinivasan, Arjun AU - Goering, Richard V AU - Tomashek, Kay M AD - Epidemic Intelligence Service and the Division of Health Care Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, hgk4@cdc.gov Y1 - 2010 PY - 2010 DA - 2010 SP - 476 EP - 484 PB - University of Chicago Press, P.O. Box 37005 Chicago IL 60637 USA, [mailto:help@press.uchicago.edu], [URL:http://www.journals.uchicago.edu/] VL - 31 IS - 5 SN - 0899-823X, 0899-823X KW - Risk Abstracts; Microbiology Abstracts B: Bacteriology KW - carbapenemase KW - Infection KW - surgery KW - Morbidity KW - Disease transmission KW - Colonization KW - Surgery KW - Risk factors KW - infection KW - Risk groups KW - Polymerase chain reaction KW - Sampling KW - Mortality KW - Electrophoresis KW - outbreaks KW - colonization KW - Wounds KW - Antimicrobial agents KW - Databases KW - ASW, Caribbean Sea, Greater Antilles, Puerto Rico KW - Reviews KW - Pulsed-field gel electrophoresis KW - Klebsiella pneumoniae KW - Hospitals KW - R2 23060:Medical and environmental health KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745978634?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Infection+Control+and+Hospital+Epidemiology&rft.atitle=Outbreak+of+Carbapenem-Resistant+Klebsiella+pneumoniae+in+Puerto+Rico+Associated+with+a+Novel+Carbapenemase+Variant&rft.au=Gregory%2C+Christopher+J%3BLlata%2C+Eloisa%3BStine%2C+Nicholas%3BGould%2C+Carolyn%3BSantiago%2C+Luis+Manuel%3BVazquez%2C+Guillermo+J%3BRobledo%2C+Iraida+E%3BSrinivasan%2C+Arjun%3BGoering%2C+Richard+V%3BTomashek%2C+Kay+M&rft.aulast=Gregory&rft.aufirst=Christopher&rft.date=2010-01-01&rft.volume=31&rft.issue=5&rft.spage=476&rft.isbn=&rft.btitle=&rft.title=Infection+Control+and+Hospital+Epidemiology&rft.issn=0899823X&rft_id=info:doi/10.1086%2F651670 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Mortality; carbapenemase; Infection; Morbidity; Disease transmission; Antimicrobial agents; Wounds; Colonization; Databases; Risk factors; Surgery; Pulsed-field gel electrophoresis; Polymerase chain reaction; Risk groups; Sampling; Hospitals; Electrophoresis; Reviews; infection; outbreaks; surgery; colonization; Klebsiella pneumoniae; ASW, Caribbean Sea, Greater Antilles, Puerto Rico DO - http://dx.doi.org/10.1086/651670 ER - TY - JOUR T1 - Evaluation of International Classification of Diseases, Ninth Revision, Clinical Modification Codes for Reporting Methicillin-Resistant Staphylococcus aureus Infections at a Hospital in Illinois AN - 745977256; 12845264 AB - Background. States, including Illinois, have passed legislation mandating the use of International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes for reporting healthcare-associated infections, such as methicillin-resistant Staphylococcus aureus (MRSA). Objective. To evaluate the sensitivity of ICD-9-CM code combinations for detection of MRSA infection and to understand implications for reporting. Methods. We reviewed discharge and microbiology databases from July through August of 2005, 2006, and 2007 for ICD-9-CM codes or microbiology results suggesting MRSA infection at a tertiary care hospital near Chicago, Illinois. Medical records were reviewed to confirm MRSA infection. Time from admission to first positive MRSA culture result was evaluated to identify hospital- onset MRSA (HO-MRSA) infections. The sensitivity of MRSA code combinations for detecting confirmed MRSA infections was calculated using all codes present in the discharge record (up to 15); the effect of reviewing only 9 diagnosis codes, the number reported to the Centers for Medicare and Medicaid Services, was also evaluated. The sensitivity of the combination of diagnosis codes for detection of HO-MRSA infections was compared with that for community-onset MRSA (CO-MRSA) infections. Results. We identified 571 potential MRSA infections with the use of screening criteria; 403 (71%) were confirmed MRSA infections, of which 61 (15%) were classified as HO-MRSA. The sensitivity of MRSA code combinations was 59% for all confirmed MRSA infections when 15 diagnoses were reviewed compared with 31% if only 9 diagnoses were reviewed. The sensitivity of code combinations was 33% for HO- MRSA infections compared with 62% for CO-MRSA infections. Conclusions. Limiting analysis to 9 diagnosis codes resulted in low sensitivity. Furthermore, code combinations were better at revealing CO-MRSA infections than HO-MRSA infections. These limitations could compromise the validity of ICD-9-CM codes for interfacility comparisons and for reporting of healthcare-associated MRSA infections. JF - Infection Control and Hospital Epidemiology AU - Schaefer, Melissa K AU - Ellingson, Katherine AU - Conover, Craig AU - Genisca, Alicia E AU - Currie, Donna AU - Esposito, Tina AU - Panttila, Laura AU - Ruestow, Peter AU - Martin, Karen AU - Cronin, Diane AU - Costello, Michael AU - Sokalski, Stephen AU - Fridkin, Scott AU - Srinivasan, Arjun AD - Division of Healthcare Quality Promotion and the Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, mschaefer@cdc.gov Y1 - 2010 PY - 2010 DA - 2010 SP - 463 EP - 468 PB - University of Chicago Press, P.O. Box 37005 Chicago IL 60637 USA, [mailto:help@press.uchicago.edu], [URL:http://www.journals.uchicago.edu/] VL - 31 IS - 5 SN - 0899-823X, 0899-823X KW - Microbiology Abstracts B: Bacteriology KW - Databases KW - Classification KW - medical records KW - Drug resistance KW - Reviews KW - Staphylococcus aureus KW - Infection KW - Legislation KW - Hospitals KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745977256?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Infection+Control+and+Hospital+Epidemiology&rft.atitle=Evaluation+of+International+Classification+of+Diseases%2C+Ninth+Revision%2C+Clinical+Modification+Codes+for+Reporting+Methicillin-Resistant+Staphylococcus+aureus+Infections+at+a+Hospital+in+Illinois&rft.au=Schaefer%2C+Melissa+K%3BEllingson%2C+Katherine%3BConover%2C+Craig%3BGenisca%2C+Alicia+E%3BCurrie%2C+Donna%3BEsposito%2C+Tina%3BPanttila%2C+Laura%3BRuestow%2C+Peter%3BMartin%2C+Karen%3BCronin%2C+Diane%3BCostello%2C+Michael%3BSokalski%2C+Stephen%3BFridkin%2C+Scott%3BSrinivasan%2C+Arjun&rft.aulast=Schaefer&rft.aufirst=Melissa&rft.date=2010-01-01&rft.volume=31&rft.issue=5&rft.spage=463&rft.isbn=&rft.btitle=&rft.title=Infection+Control+and+Hospital+Epidemiology&rft.issn=0899823X&rft_id=info:doi/10.1086%2F651665 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Databases; Classification; medical records; Reviews; Drug resistance; Infection; Legislation; Hospitals; Staphylococcus aureus DO - http://dx.doi.org/10.1086/651665 ER - TY - JOUR T1 - Occupational injuries among emergency responders AN - 745631036; 12739876 AB - Background Emergency responders frequently incur injuries while providing medical, fire, and law enforcement services. National surveillance systems provide fragmented perspectives on responder injuries because they omit specific classes of workers (e.g., government or volunteers); they report only selected injuries; and employment information is incomplete. Methods We characterized injuries among emergency medical services (EMS), firefighting, and police occupations by using data from the National Electronic Injury Surveillance System - Occupational Supplement (NEISS-Work) for injuries treated in U.S. hospital emergency departments in 2000-2001. Results Sprains and strains were the leading injury (33-41%) among EMS, firefighter, and police occupations. Police officers and career firefighters had the highest injury rates (8.5 and 7.4 injuries per 100 full-time equivalent workers, respectively). Conclusions The physical demands of emergency response are a leading cause of injuries that may benefit from similar interventions across the occupations. To assess risk, improved exposure data need to be acquired, particularly for volunteers. Am. J. Ind. Med. 53:1-11, 2010. Published 2009 Wiley-Liss, Inc. JF - American Journal of Industrial Medicine AU - Reichard, Audrey A AU - Jackson, Larry L AD - Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Morgantown, West Virginia, akr5@cdc.gov Y1 - 2010/01// PY - 2010 DA - Jan 2010 SP - 1 EP - 11 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 USA VL - 53 IS - 1 SN - 0271-3586, 0271-3586 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Fires KW - employment KW - firefighter services KW - Injuries KW - Occupational safety KW - careers KW - USA KW - police KW - intervention KW - Emergency preparedness KW - law enforcement KW - emergency medical services KW - Occupational exposure KW - Hospitals KW - R2 23080:Industrial and labor KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745631036?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Occupational+injuries+among+emergency+responders&rft.au=Reichard%2C+Audrey+A%3BJackson%2C+Larry+L&rft.aulast=Reichard&rft.aufirst=Audrey&rft.date=2010-01-01&rft.volume=53&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=02713586&rft_id=info:doi/10.1002%2Fajim.20772 L2 - http://www3.interscience.wiley.com/journal/122677318/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Fires; employment; Injuries; firefighter services; Occupational safety; careers; police; Emergency preparedness; intervention; law enforcement; Occupational exposure; emergency medical services; Hospitals; USA DO - http://dx.doi.org/10.1002/ajim.20772 ER - TY - JOUR T1 - ROPS Performance during Field Upset and Static Testing AN - 744618389; 12912712 AB - Agriculture remains one of the most hazardous occupations in the U.S. By conservative estimates, tractor overturns alone claim 120 lives annually. A rollover protective structure (ROPS) and a seatbelt are a highly effective engineering safety control that can prevent many of these fatalities and reduce the severity of injuries associated with tractor overturn. SAE J2194 is a consensus performance standard established for agricultural ROPS. According to this standard, satisfactory ROPS performance can be demonstrated through static testing, field upset testing, or impact testing. A previous modeling study suggested that static testing may underpredict the strain induced in a ROPS during a field upset. In the current study, field upset testing and laboratory static testing results were compared. Field upset testing included six rear and six side upset tests performed according to SAE J2194 guidelines. Additionally, static testing was performed on a ROPS of the same model. The results support findings from the modeling study. Near the lowest sections of the ROPS, the plastic strain resulting from rear upset testing exceeded the plastic strain from static testing for 18 of 24 data points. Conversely, the ROPS plastic strain from side upset testing was typically less than plastic strain from laboratory static testing. However, data indicate that the side upset test may not be very repeatable. This study suggests that the longitudinal loading energy criterion for static testing might not be a conservative predictor of rear upset ROPS response. JF - Journal of Agricultural Safety and Health AU - Harris, J R AU - McKenzie, EA Jr AU - Etherton, J R AU - Cantis, D M AU - Ronaghi, M AD - NIOSH Division of Safety Research, MS G800, 1095 Willowdale Rd., Morgantown, West Virginia, USA, jharris@cdc.gov Y1 - 2010/01// PY - 2010 DA - Jan 2010 SP - 5 EP - 18 VL - 16 IS - 1 SN - 1074-7583, 1074-7583 KW - Health & Safety Science Abstracts KW - Mortality KW - USA KW - safety engineering KW - Injuries KW - guidelines KW - agriculture KW - rollover KW - Agricultural equipment KW - seat belts KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/744618389?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Agricultural+Safety+and+Health&rft.atitle=ROPS+Performance+during+Field+Upset+and+Static+Testing&rft.au=Harris%2C+J+R%3BMcKenzie%2C+EA+Jr%3BEtherton%2C+J+R%3BCantis%2C+D+M%3BRonaghi%2C+M&rft.aulast=Harris&rft.aufirst=J&rft.date=2010-01-01&rft.volume=16&rft.issue=1&rft.spage=5&rft.isbn=&rft.btitle=&rft.title=Journal+of+Agricultural+Safety+and+Health&rft.issn=10747583&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Mortality; safety engineering; Injuries; guidelines; agriculture; rollover; seat belts; Agricultural equipment; USA ER - TY - JOUR T1 - Inhibition of AP-1 and MAPK signaling and activation of Nrf2/ARE pathway by quercitrin. AN - 734167324; 19956833 AB - Quercitrin, glycosylated form of flavonoid compounds, is widely distributed in nature. Extensive studies have demonstrated that quercitrin exhibits strong antioxidant and anti-carcinogenic activities. However, the molecular mechanism is poorly understood. The present study examines the effects of quercitrin on tumor promotion in mouse JB6 cells, a validated model for screening cancer chemopreventive agents and elucidating the molecular mechanisms. Quercitrin blocked TPA-induced neoplastic transformation in JB6 P+ cells. Pretreatment of JB6 cells with quercitrin down-regulated transactivation of AP-1 and NF-kappaB induced by UVB or TPA. In the skin of AP-1-luciferase transgenic mice, topical treatment of the mouse with quercitrin markedly blocked the TPA-induced AP-1 transactivation. Further studies indicated that these inhibitory actions appear to be mediated through the inhibition of MAPKs phosphorylation, including ERKs, p38 kinase, and JNKs. In addition, quercitrin stimulated the activation of NF-E2-related factor (Nrf2) and GST ARE-luciferase activity. Comet assays showed that quercitrin could block DNA damage induced by UVB. To our knowledge, these results provide the first evidence that quercitrin contributes to the inhibition of neoplastic transformation by blocking activation of the MAPK pathway and stimulation of cellular protection signaling. Moreover, to our knowledge, these findings provide the first molecular basis for the anti-carcinogenic action of quercitrin. JF - International journal of oncology AU - Ding, Min AU - Zhao, Jinshun AU - Bowman, Linda AU - Lu, Yongju AU - Shi, Xianglin AD - Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA. mid5@cdc.gov Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 59 EP - 67 VL - 36 IS - 1 KW - Antioxidants KW - 0 KW - Carcinogens KW - Enzyme Inhibitors KW - NF-E2-Related Factor 2 KW - NFE2L2 protein, human KW - Transcription Factor AP-1 KW - quercitrin KW - 2Y8906LC5P KW - Quercetin KW - 9IKM0I5T1E KW - Index Medicus KW - Comet Assay KW - Animals KW - Enzyme Activation KW - Mice KW - Mice, Transgenic KW - Transcriptional Activation KW - Male KW - Female KW - Gene Expression Regulation, Neoplastic KW - MAP Kinase Signaling System KW - Antioxidants -- metabolism KW - Transcription Factor AP-1 -- antagonists & inhibitors KW - Quercetin -- analogs & derivatives KW - NF-E2-Related Factor 2 -- antagonists & inhibitors KW - Enzyme Inhibitors -- pharmacology KW - Response Elements KW - Quercetin -- pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/734167324?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+journal+of+oncology&rft.atitle=Psychosocial+work+environment+and+prediction+of+job+satisfaction+among+Swedish+registered+nurses+and+physicians%E2%80%94A+follow%E2%80%90up+study&rft.au=J%C3%B6nsson%2C+Sandra&rft.aulast=J%C3%B6nsson&rft.aufirst=Sandra&rft.date=2012-06-01&rft.volume=26&rft.issue=2&rft.spage=236&rft.isbn=&rft.btitle=&rft.title=Scandinavian+Journal+of+Caring+Sciences&rft.issn=02839318&rft_id=info:doi/10.1111%2Fj.1471-6712.2011.00924.x LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-02-22 N1 - Date created - 2009-12-03 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - A health hazard evaluation of antimony exposure in fire fighters. AN - 733988532; 20042882 AB - Some firefighter station uniforms contain the flame-retardant, antimony trioxide. National Institute for Occupational Safety and Health investigated a possible outbreak of antimony toxicity wherein 30 firefighters reported elevated antimony levels on hair analyses. We surveyed and collected urine samples from firefighters not wearing (Fire Department A) and wearing (Fire Department B) antimony-containing pants. Urine antimony concentrations were measured and adjusted for creatinine. All 20 participating firefighters from Fire Department A and 41 (97.6%) of 42 participating firefighters from Fire Department B had urine antimony concentrations below or within the national reference range. No differences in urine antimony levels between departments were detected. Wearing antimony-containing uniforms does not pose a risk for antimony toxicity. This investigation highlights the importance of using validated methods for toxicity determination and of accurate, timely risk communication. JF - Journal of occupational and environmental medicine AU - de Perio, Marie A AU - Durgam, Srinivas AU - Caldwell, Kathleen L AU - Eisenberg, Judith AD - Division of Surveillance, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA. Mdeperio@cdc.gov Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 81 EP - 84 VL - 52 IS - 1 KW - Flame Retardants KW - 0 KW - Antimony KW - 9IT35J3UV3 KW - Index Medicus KW - United States KW - Humans KW - Hair -- chemistry KW - Flame Retardants -- adverse effects KW - Protective Clothing -- adverse effects KW - National Institute for Occupational Safety and Health (U.S.) KW - Male KW - Female KW - Risk Assessment KW - Fires KW - Occupational Exposure -- adverse effects KW - Antimony -- urine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733988532?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+occupational+and+environmental+medicine&rft.atitle=A+health+hazard+evaluation+of+antimony+exposure+in+fire+fighters.&rft.au=de+Perio%2C+Marie+A%3BDurgam%2C+Srinivas%3BCaldwell%2C+Kathleen+L%3BEisenberg%2C+Judith&rft.aulast=de+Perio&rft.aufirst=Marie&rft.date=2010-01-01&rft.volume=52&rft.issue=1&rft.spage=81&rft.isbn=&rft.btitle=&rft.title=Journal+of+occupational+and+environmental+medicine&rft.issn=1536-5948&rft_id=info:doi/10.1097%2FJOM.0b013e3181c7514a LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-04-26 N1 - Date created - 2010-01-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1097/JOM.0b013e3181c7514a ER - TY - JOUR T1 - Close encounters of the small kind: adverse effects of man-made materials interfacing with the nano-cosmos of biological systems. AN - 733714751; 20055698 AB - Engineered nanomaterials have unique physico-chemical properties that make them promising for many technological and biomedical applications, including tissue regeneration, drug and gene delivery, and in vivo monitoring of disease processes. However, with the burgeoning capabilities to manipulate structures at the nano-scale, intentional as well as unintentional human exposures to engineered nanomaterials are set to increase. Nanotoxicology is an emerging discipline focused on understanding the properties of engineered nanomaterials and their interactions with biological systems, and may be viewed as the study of the undesirable interference between man-made nanomaterials and cellular nanostructures or nanomachines. In this review, we discuss recognition of engineered nanomaterials by the immune system, our primary defense system against foreign invasion. Moreover, as oxidative stress is believed to be one of the major deleterious consequences of exposure to nanomaterials, we explore triggering of pro- and antioxidant pathways as well as biomarkers of oxidative stress. Finally, we highlight in vivo studies of the toxicological outcomes of engineered nanomaterials, including carbon nanotubes, with an emphasis on inflammation and genotoxic responses. JF - Annual review of pharmacology and toxicology AU - Shvedova, Anna A AU - Kagan, Valerian E AU - Fadeel, Bengt AD - Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, West Virginia University, Morgantown, USA. ATS1@CDC.GOV Y1 - 2010 PY - 2010 DA - 2010 SP - 63 EP - 88 VL - 50 KW - Nanotubes, Carbon KW - 0 KW - Index Medicus KW - Animals KW - Particle Size KW - Humans KW - Oxidative Stress KW - Cell Physiological Phenomena -- drug effects KW - Nanotubes, Carbon -- adverse effects KW - Nanotechnology KW - Nanostructures -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733714751?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annual+review+of+pharmacology+and+toxicology&rft.atitle=Close+encounters+of+the+small+kind%3A+adverse+effects+of+man-made+materials+interfacing+with+the+nano-cosmos+of+biological+systems.&rft.au=Shvedova%2C+Anna+A%3BKagan%2C+Valerian+E%3BFadeel%2C+Bengt&rft.aulast=Shvedova&rft.aufirst=Anna&rft.date=2010-01-01&rft.volume=50&rft.issue=&rft.spage=63&rft.isbn=&rft.btitle=&rft.title=Annual+review+of+pharmacology+and+toxicology&rft.issn=1545-4304&rft_id=info:doi/10.1146%2Fannurev.pharmtox.010909.105819 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-03-17 N1 - Date created - 2010-01-08 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1146/annurev.pharmtox.010909.105819 ER - TY - JOUR T1 - Hospitalization and mortality among primarily nonbreastfed children during a large outbreak of diarrhea and malnutrition in Botswana, 2006. AN - 733606275; 19801943 AB - In 2006, a pediatric diarrhea outbreak occurred in Botswana, coinciding with heavy rains. Surveillance recorded a 3 times increase in cases and a 25 fold increase in deaths between January and March. Botswana has high HIV prevalence among pregnant women (33.4% in 2005), and an estimated 35% of all infants under the age of 6 months are not breastfed. We followed all children <5 years old with diarrhea in the country's second largest referral hospital at the peak of the outbreak by chart review, interviewed mothers, and conducted laboratory testing for HIV and enteric pathogens. Of 153 hospitalized children with diarrhea, 97% were <2 years old; 88% of these were not breastfeeding. HIV was diagnosed in 18% of children and 64% of mothers. Cryptosporidium and enteropathogenic Escherichia coli were common; many children had multiple pathogens. Severe acute malnutrition (kwashiorkor or marasmus) developed in 38 (25%) patients, and 33 (22%) died. Kwashiorkor increased risk for death (relative risk 2.0; P = 0.05); only one breastfeeding child died. Many children who died had been undersupplied with formula. Most of the severe morbidity and mortality in this outbreak occurred in children who were HIV negative and not breastfed. Feeding and nutritional factors were the most important determinants of severe illness and death. Breastfeeding is critical to infant survival in the developing world, and support for breastfeeding among HIV-negative women, and HIV-positive women who cannot formula feed safely, may prevent further high-mortality outbreaks. JF - Journal of acquired immune deficiency syndromes (1999) AU - Creek, Tracy L AU - Kim, Andrea AU - Lu, Lydia AU - Bowen, Anna AU - Masunge, Japhter AU - Arvelo, Wences AU - Smit, Molly AU - Mach, Ondrej AU - Legwaila, Keitumetse AU - Motswere, Catherine AU - Zaks, Laurel AU - Finkbeiner, Thomas AU - Povinelli, Laura AU - Maruping, Maruping AU - Ngwaru, Gibson AU - Tebele, Goitebetswe AU - Bopp, Cheryl AU - Puhr, Nancy AU - Johnston, Stephanie P AU - Dasilva, Alexandre J AU - Bern, Caryn AU - Beard, R S AU - Davis, Margarett K AD - Centers for Disease Control and Prevention, Global AIDS Program, 1600 Clifton Rd NE, Mailstop E-04, Atlanta, GA 30033, USA. tgc0@cdc.gov Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 14 EP - 19 VL - 53 IS - 1 KW - Anti-Bacterial Agents KW - 0 KW - Index Medicus KW - AIDS/HIV KW - Infectious Disease Transmission, Vertical -- prevention & control KW - Infectious Disease Transmission, Vertical -- statistics & numerical data KW - Anti-Bacterial Agents -- therapeutic use KW - Enterobacteriaceae -- isolation & purification KW - Humans KW - Anti-Bacterial Agents -- adverse effects KW - Infant Mortality KW - Child, Preschool KW - Infant Formula -- statistics & numerical data KW - Botswana -- epidemiology KW - Infant KW - Risk Factors KW - Mothers -- statistics & numerical data KW - Developing Countries KW - Follow-Up Studies KW - Hospitalization -- statistics & numerical data KW - Female KW - Breast Feeding -- statistics & numerical data KW - Diarrhea -- mortality KW - HIV Infections -- transmission KW - Diarrhea -- microbiology KW - Disease Outbreaks KW - HIV-1 KW - Child Nutrition Disorders -- microbiology KW - Child Nutrition Disorders -- virology KW - Breast Feeding -- epidemiology KW - Diarrhea -- drug therapy KW - HIV Infections -- microbiology KW - HIV Infections -- epidemiology KW - Child Nutrition Disorders -- epidemiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733606275?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+acquired+immune+deficiency+syndromes+%281999%29&rft.atitle=Hospitalization+and+mortality+among+primarily+nonbreastfed+children+during+a+large+outbreak+of+diarrhea+and+malnutrition+in+Botswana%2C+2006.&rft.au=Creek%2C+Tracy+L%3BKim%2C+Andrea%3BLu%2C+Lydia%3BBowen%2C+Anna%3BMasunge%2C+Japhter%3BArvelo%2C+Wences%3BSmit%2C+Molly%3BMach%2C+Ondrej%3BLegwaila%2C+Keitumetse%3BMotswere%2C+Catherine%3BZaks%2C+Laurel%3BFinkbeiner%2C+Thomas%3BPovinelli%2C+Laura%3BMaruping%2C+Maruping%3BNgwaru%2C+Gibson%3BTebele%2C+Goitebetswe%3BBopp%2C+Cheryl%3BPuhr%2C+Nancy%3BJohnston%2C+Stephanie+P%3BDasilva%2C+Alexandre+J%3BBern%2C+Caryn%3BBeard%2C+R+S%3BDavis%2C+Margarett+K&rft.aulast=Creek&rft.aufirst=Tracy&rft.date=2010-01-01&rft.volume=53&rft.issue=1&rft.spage=14&rft.isbn=&rft.btitle=&rft.title=Journal+of+acquired+immune+deficiency+syndromes+%281999%29&rft.issn=1944-7884&rft_id=info:doi/10.1097%2FQAI.0b013e3181bdf676 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-01-19 N1 - Date created - 2009-12-29 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1097/QAI.0b013e3181bdf676 ER - TY - JOUR T1 - Follow-up for cervical abnormalities in a managed care plan, 1999-2004 AN - 57355342; 201006089 AB - Objective The objective of this study was to determine the follow-up for women after receiving an abnormal Pap test before and after the updated American Society of Colposcopic and Cervical Pathology (ASCCP) guidelines for management of abnormal cytology. Methods In 1999 and 2004, women who had been enrolled in a US health care plan for at least 21 months and were between 18 and 70 years of age were included. We calculated differences in type of follow-up between the time periods before and after ASCCP guideline changes in 2002. Results Overall, 1.7 million women met study criteria and received at least one Pap test. Overall, 227,802 (14%) women received additional follow-up. Of these women, 73% had a repeat Pap test within 9 months as their first follow-up, 13% received colposcopy, and 7% had other events. The proportion of women receiving a repeat Pap test decreased significantly during the post-guideline time period. The odds of a woman receiving a colposcopy versus a repeat Pap test were 41% higher in the post-guideline period, after controlling for other variables. Conclusions Our findings indicate that for the time period after the ASCCP guidelines changed, more colposcopies and fewer repeat Pap tests were performed as a follow-up of abnormal Pap test. [Copyright Elsevier B.V.] JF - Preventive Medicine AU - Benard, V B AU - Berkman, N D AU - Kuo, T AU - Martin, C K AU - Richardson, L C AD - Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Division of Cancer Prevention and Control, Mailstop K-55, 4770 Buford Hwy NE, Atlanta, GA 30341, USA Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 81 EP - 85 PB - Elsevier Ltd, The Netherlands VL - 50 IS - 1-2 SN - 0091-7435, 0091-7435 KW - Cervical cancer Claims data Abnormal Pap tests KW - Screening KW - Managed care KW - Pathology KW - Women KW - Cervical cancer KW - Colposcopy KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/57355342?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Preventive+Medicine&rft.atitle=Follow-up+for+cervical+abnormalities+in+a+managed+care+plan%2C+1999-2004&rft.au=Benard%2C+V+B%3BBerkman%2C+N+D%3BKuo%2C+T%3BMartin%2C+C+K%3BRichardson%2C+L+C&rft.aulast=Benard&rft.aufirst=V&rft.date=2010-01-01&rft.volume=50&rft.issue=1-2&rft.spage=81&rft.isbn=&rft.btitle=&rft.title=Preventive+Medicine&rft.issn=00917435&rft_id=info:doi/10.1016%2Fj.ypmed.2009.11.005 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-04-07 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Screening; Cervical cancer; Women; Colposcopy; Managed care; Pathology DO - http://dx.doi.org/10.1016/j.ypmed.2009.11.005 ER - TY - JOUR T1 - Increased Penicillin Nonsusceptibility of Nonvaccine-Serotype Invasive Pneumococci Other than Serotypes 19A and 6A in Post-7-Valent Conjugate Vaccine Era AN - 21501198; 12491932 AB - According to population-based invasive pneumococcal surveillance in the United States during 2007, 898 (26%) of 3,511 isolates were penicillin nonsusceptible. Non-7-valent pneumococcal conjugate vaccine (PCV7) serotypes other than 19A accounted for 40% of these penicillin-nonsusceptible isolates; of these, serotypes 15A (11%), 23A (8%), 35B (8%), and 6C (5%) were most common (cumulatively 32% of penicillin-nonsusceptible isolates). Each except 6C represented a single serotype and clonal complex combination that predated the introduction of PCV7. We evaluated the genetic characteristics and nonsusceptibility to penicillin of non-PCV7 serotypes, and we found increased proportions of specific penicillin-nonsusceptible clones in serotypes 15A, 23A, 35B, and 6C, which potentially indicates a basic change of population structure within these individual serotypes. JF - Journal of Infectious Diseases AU - Gertz, Robert E AU - Li, Zhongya AU - Pimenta, Fabiana C AU - Jackson, Delois AU - Juni, Billie A AU - Lynfield, Ruth AU - Jorgensen, James H AU - Carvalho, Maria da Gloria AU - Beall, Bernard W AD - Respiratory Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, bbeall@cdc.gov Y1 - 2010///0, PY - 2010 DA - 0, 2010 SP - 770 EP - 775 PB - University of Chicago Press, P.O. Box 37005 Chicago IL 60637 USA, [mailto:help@press.uchicago.edu], [URL:http://www.journals.uchicago.edu/] VL - 201 IS - 5 SN - 0022-1899, 0022-1899 KW - Microbiology Abstracts B: Bacteriology KW - Streptococcus pneumoniae KW - Serotypes KW - Population structure KW - Vaccines KW - Penicillin KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21501198?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Increased+Penicillin+Nonsusceptibility+of+Nonvaccine-Serotype+Invasive+Pneumococci+Other+than+Serotypes+19A+and+6A+in+Post-7-Valent+Conjugate+Vaccine+Era&rft.au=Gertz%2C+Robert+E%3BLi%2C+Zhongya%3BPimenta%2C+Fabiana+C%3BJackson%2C+Delois%3BJuni%2C+Billie+A%3BLynfield%2C+Ruth%3BJorgensen%2C+James+H%3BCarvalho%2C+Maria+da+Gloria%3BBeall%2C+Bernard+W&rft.aulast=Gertz&rft.aufirst=Robert&rft.date=2010-01-01&rft.volume=201&rft.issue=5&rft.spage=770&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Serotypes; Population structure; Vaccines; Penicillin; Streptococcus pneumoniae ER - TY - JOUR T1 - Bacteriophage Cocktail for the Prevention of Biofilm Formation by Pseudomonas aeruginosa on Catheters in an In Vitro Model System AN - 21488717; 12492404 AB - Microorganisms develop biofilms on indwelling medical devices and are associated with device-related infections, resulting in substantial morbidity and mortality. This study investigated the effect of pretreating hydrogel-coated catheters with Pseudomonas aeruginosa bacteriophages on biofilm formation by P. aeruginosa in an in vitro model. Hydrogel-coated catheters were exposed to a 10 log10 PFU ml-1 lysate of P. aeruginosa phage M4 for 2 h at 37C prior to bacterial inoculation. The mean viable biofilm count on untreated catheters was 6.87 log10 CFU cm-2 after 24 h. The pretreatment of catheters with phage reduced this value to 4.03 log10 CFU cm-2 (P < 0.001). Phage treatment immediately following bacterial inoculation also reduced biofilm viable counts (4.37 log10 CFU cm-2 reduction; P < 0.001). The regrowth of biofilms on phage-treated catheters occurred between 24 and 48 h, but supplemental treatment with phage at 24 h significantly reduced biofilm regrowth (P < 0.001). Biofilm isolates resistant to phage M4 were recovered from catheters pretreated with phage. The phage susceptibility profiles of these isolates were used to guide the development of a five-phage cocktail from a larger library of P. aeruginosa phages. The pretreatment of catheters with this cocktail reduced the 48-h mean biofilm cell density by 99.9% (from 7.13 to 4.13 log10 CFU cm-2; P < 0.001), but fewer biofilm isolates were resistant to these phages. These results suggest the potential of applying phages, especially phage cocktails, to the surfaces of indwelling medical devices for mitigating biofilm formation by clinically relevant bacteria. JF - Antimicrobial Agents & Chemotherapy AU - Fu, Weiling AU - Forster, Terri AU - Mayer, Oren AU - Curtin, John J AU - Lehman, Susan M AU - Donlan, Rodney M AD - Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, rld8@cdc.gov Y1 - 2010/01// PY - 2010 DA - Jan 2010 SP - 397 EP - 404 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 54 IS - 1 SN - 0066-4804, 0066-4804 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts KW - Phages KW - Bacteria KW - Mortality KW - Cell density KW - Infection KW - Morbidity KW - Colony-forming cells KW - Catheters KW - Inoculation KW - Microorganisms KW - Biofilms KW - Pseudomonas aeruginosa KW - A 01340:Antibiotics & Antimicrobials KW - V 22340:Antiviral Agents KW - J 02430:Symbiosis, Antibiosis & Phages UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21488717?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Bacteriophage+Cocktail+for+the+Prevention+of+Biofilm+Formation+by+Pseudomonas+aeruginosa+on+Catheters+in+an+In+Vitro+Model+System&rft.au=Fu%2C+Weiling%3BForster%2C+Terri%3BMayer%2C+Oren%3BCurtin%2C+John+J%3BLehman%2C+Susan+M%3BDonlan%2C+Rodney+M&rft.aulast=Fu&rft.aufirst=Weiling&rft.date=2010-01-01&rft.volume=54&rft.issue=1&rft.spage=397&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.00669-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Phages; Mortality; Colony-forming cells; Cell density; Microorganisms; Inoculation; Catheters; Biofilms; Infection; Morbidity; Bacteria; Pseudomonas aeruginosa DO - http://dx.doi.org/10.1128/AAC.00669-09 ER - TY - JOUR T1 - Development of Two Avidity-Based Assays to Detect Recent HIV Type 1 Seroconversion Using a Multisubtype gp41 Recombinant Protein AN - 21335837; 12339290 AB - Current laboratory methods to detect recent HIV-1 infection for the estimation of incidence have various limitations, including varying performance in different subtypes or populations. Therefore, new methods are needed to detect recent infections with increased specificity. We developed a recombinant protein, rIDR-M, that covered divergent sequences from the immunodominant region (IDR) of gp41 from all major subtypes and recombinants of HIV-1 group M and expressed in Escherichia coli. The rIDR-M protein was highly reactive with HIV antibodies in sera from different subtypes and equivalently detected antibodies to divergent subtypes B and AE from Thailand, in contrast to individual gp41 peptides derived from respective subtypes, suggesting that it can be used for incidence assays. The protein was used in two different assay formats to measure antibody avidity: (1) a two-well avidity index assay (AI-EIA) and (2) a new one-well limiting antigen avidity assay (LAg-avidity EIA), both with a pH 3.0 buffer to dissociate low-avidity antibodies present during early infection. Limiting the amount of antigen allowed detection of recent HIV-1 infection, with or without dissociation buffer, but the detection was most efficient when the pH 3.0 dissociation buffer was included. When a well-characterized 41-member seroincidence panel (20 recent and 21 long-term) was used, both the two-well AI-EIA and one-well LAg-avidity EIA efficiently distinguished recent and long-term infections. The new avidity-based assays using rIDR-M antigen may improve the accuracy of detecting recent HIV-1 infection and allow a better estimation of incidence in diverse HIV-1 subtypes. JF - AIDS Research and Human Retroviruses AU - Wei, X AU - Liu, X AU - Dobbs, T AU - Kuehl, D AU - Nkengasong, J N AU - Hu, D J AU - Parekh, B S AD - International Laboratory Branch, Division of Global AIDS, Centers for Disease Control and Prevention, MS-G19, 1600 Clifton Road, Bldg, 15/2611 Atlanta, Georgia 30333, USA, bparekh@cdc.gov Y1 - 2010/01// PY - 2010 DA - Jan 2010 SP - 61 EP - 71 VL - 26 IS - 1 SN - 0889-2229, 0889-2229 KW - Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts KW - Antibodies KW - Retrovirus KW - glycoprotein gp41 KW - Avidity KW - Human immunodeficiency virus 1 KW - Escherichia coli KW - Seroconversion KW - Infection KW - pH effects KW - V 22360:AIDS and HIV KW - J 02300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21335837?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+Research+and+Human+Retroviruses&rft.atitle=Development+of+Two+Avidity-Based+Assays+to+Detect+Recent+HIV+Type+1+Seroconversion+Using+a+Multisubtype+gp41+Recombinant+Protein&rft.au=Wei%2C+X%3BLiu%2C+X%3BDobbs%2C+T%3BKuehl%2C+D%3BNkengasong%2C+J+N%3BHu%2C+D+J%3BParekh%2C+B+S&rft.aulast=Wei&rft.aufirst=X&rft.date=2010-01-01&rft.volume=26&rft.issue=1&rft.spage=61&rft.isbn=&rft.btitle=&rft.title=AIDS+Research+and+Human+Retroviruses&rft.issn=08892229&rft_id=info:doi/10.1089%2Faid.2009.0133 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-10-15 N1 - SubjectsTermNotLitGenreText - Antibodies; glycoprotein gp41; Avidity; Seroconversion; Infection; pH effects; Retrovirus; Human immunodeficiency virus 1; Escherichia coli DO - http://dx.doi.org/10.1089/aid.2009.0133 ER - TY - JOUR T1 - Laboratory worker knowledge, attitudes and practices towards smallpox vaccine AN - 21330846; 11939647 AB - Background Recent cases of laboratory-acquired vaccinia virus (VV) infection highlight the need for laboratory safety.Aims To determine laboratory worker adherence to the Advisory Committee for Immunization Practices smallpox vaccination recommendations, assess potential barriers to vaccination and determine the influence of training on laboratory worker attitudes.Methods Ninety-two laboratory workers in Pennsylvania were contacted and asked to complete an online survey about VV usage; 45 responded.Results Eighty-seven per cent had received a smallpox vaccination in their lifetime; 73% received vaccination in the past 10 years. More workers had been given training regarding the potential risks, versus the potential benefits of vaccination, and most perceived that adverse outcomes were more likely to occur following vaccination versus accidental infection.Conclusions The results of this study suggest that the main barrier to vaccination may be fear associated with possible vaccine adverse effects and a willingness to risk accidental infection rather than be vaccinated. More information and training about the potential benefits of vaccination, as well as the potential adverse outcomes associated with accidental infection, is therefore warranted. JF - Occupational Medicine AU - Benzekri, Noelle AU - Goldman, Erinn AU - Lewis, Felicia AU - Johnson, Carolyn C AU - Reynolds, Stanley M AU - Reynolds, Mary G AU - Damon, Inger K AD - 1 Poxvirus and Rabies Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA, nzr6@cdc.gov nzr6@cdc.gov Y1 - 2010/01// PY - 2010 DA - Jan 2010 SP - 75 EP - 77 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP UK VL - 60 IS - 1 SN - 0962-7480, 0962-7480 KW - Virology & AIDS Abstracts; Immunology Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - Knowledge attitudes and practices KW - smallpox vaccine KW - vaccinia virus KW - WR-vaccinia KW - vaccines KW - Training KW - Fear KW - advisory committees KW - Infection KW - Vaccination KW - attitudes KW - immunization KW - Smallpox KW - Workers KW - Vaccinia virus KW - Perception KW - USA, Pennsylvania KW - infection KW - Vaccines KW - Occupational exposure KW - Side effects KW - R2 23080:Industrial and labor KW - F 06905:Vaccines KW - V 22320:Replication KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21330846?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Occupational+Medicine&rft.atitle=Laboratory+worker+knowledge%2C+attitudes+and+practices+towards+smallpox+vaccine&rft.au=Benzekri%2C+Noelle%3BGoldman%2C+Erinn%3BLewis%2C+Felicia%3BJohnson%2C+Carolyn+C%3BReynolds%2C+Stanley+M%3BReynolds%2C+Mary+G%3BDamon%2C+Inger+K&rft.aulast=Benzekri&rft.aufirst=Noelle&rft.date=2010-01-01&rft.volume=60&rft.issue=1&rft.spage=75&rft.isbn=&rft.btitle=&rft.title=Occupational+Medicine&rft.issn=09627480&rft_id=info:doi/10.1093%2Foccmed%2Fkqp120 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Smallpox; Workers; Fear; Vaccines; Infection; Vaccination; Side effects; immunization; vaccines; Perception; Training; advisory committees; infection; attitudes; Occupational exposure; Vaccinia virus; USA, Pennsylvania DO - http://dx.doi.org/10.1093/occmed/kqp120 ER - TY - JOUR T1 - Surveillance of Transmitted HIV Type 1 Drug Resistance in Newly Diagnosed HIV Type 1-Infected Patients in Shandong Province, China AN - 21321359; 12339294 AB - A survey to measure transmitted HIV-1 drug resistance (DR) was conducted in 2006 following the World Health Organization threshold survey protocol. Dried blood spots (DBS) were prepared from 53 newly HIV-1-diagnosed patients. Protease and reverse transcriptase (RT) gene regions were sequenced using a broadly sensitive genotyping assay and analyses to identify DR mutations and determine phylogeny of the HIV-1 strains were conducted. Forty-six of the 47 successfully genotyped DBS had no transmitted DR mutations; one had an NNRTI mutation (K101E) in the RT region. Phylogenetic analyses revealed 21 (44.7%) were CRF01_AE, 9 (19.1%) B, 6 (12.8%) CRF07_BC, 3 (6.4%) each of CRF08_BC and C, and 2 (4.3%) B/C unique recombinant forms (URF). The remaining three were one each of A/B, A/C, and unclassifiable. Our analyses indicate that the prevalence of transmitted DR in this population is low and the HIV-1 epidemic in the area was characterized by multiple subtypes and recombinant forms. JF - AIDS Research and Human Retroviruses AU - Zhang, J AU - Kang, D AU - Fu, J AU - Sun, X AU - Lin, B AU - Bi, Z AU - Nkengasong, J N AU - Yang, C AD - International Laboratory Branch, Mail Stop A-11, Division of Global AIDS, NCHHSTP, Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Atlanta, Georgia 30333, USA, CYang1@cdc.gov Y1 - 2010/01// PY - 2010 DA - Jan 2010 SP - 99 EP - 103 VL - 26 IS - 1 SN - 0889-2229, 0889-2229 KW - Biotechnology and Bioengineering Abstracts; Virology & AIDS Abstracts KW - Phylogeny KW - Blood KW - Retrovirus KW - Epidemics KW - Drug resistance KW - Genotyping KW - Human immunodeficiency virus 1 KW - RNA-directed DNA polymerase KW - Proteinase KW - Corticotropin-releasing hormone KW - Mutation KW - W 30925:Genetic Engineering KW - V 22360:AIDS and HIV UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21321359?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+Research+and+Human+Retroviruses&rft.atitle=Surveillance+of+Transmitted+HIV+Type+1+Drug+Resistance+in+Newly+Diagnosed+HIV+Type+1-Infected+Patients+in+Shandong+Province%2C+China&rft.au=Zhang%2C+J%3BKang%2C+D%3BFu%2C+J%3BSun%2C+X%3BLin%2C+B%3BBi%2C+Z%3BNkengasong%2C+J+N%3BYang%2C+C&rft.aulast=Zhang&rft.aufirst=J&rft.date=2010-01-01&rft.volume=26&rft.issue=1&rft.spage=99&rft.isbn=&rft.btitle=&rft.title=AIDS+Research+and+Human+Retroviruses&rft.issn=08892229&rft_id=info:doi/10.1089%2Faid.2009.0184 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-10-15 N1 - SubjectsTermNotLitGenreText - Phylogeny; Blood; Epidemics; Genotyping; Drug resistance; RNA-directed DNA polymerase; Proteinase; Mutation; Corticotropin-releasing hormone; Retrovirus; Human immunodeficiency virus 1 DO - http://dx.doi.org/10.1089/aid.2009.0184 ER - TY - JOUR T1 - Climatic Predictors of the Intra- and Inter-Annual Distributions of Plague Cases in New Mexico Based on 29 Years of Animal-Based Surveillance Data AN - 21310162; 11847935 AB - Within the United States, the majority of human plague cases are reported from New Mexico. We describe climatic factors involved in intra- and inter-annual plague dynamics using animal-based surveillance data from that state. Unlike the clear seasonal pattern observed at lower elevations, cases occur randomly throughout the year at higher elevations. Increasing elevation corresponded with delayed mean time in case presentation. Using local meteorological data (previous year mean annual precipitation, total degrees over 27C 3 years before and maximum winter temperatures 4 years before) we built a time-series model predicting annual case load that explained 75% of the variance in pet cases between years. Moreover, we found a significant correlation with observed annual human cases and predicted pet cases. Because covariates were time-lagged by at least 1 year, intensity of case loads can be predicted in advance of a plague season. Understanding associations between environmental and meteorological factors can be useful for anticipating future disease trends. JF - American Journal of Tropical Medicine and Hygiene AU - Brown, HE AU - Ettestad, P AU - Reynolds, P J AU - Brown, T L AU - Hatton, E S AU - Holmes, J L AU - Glass, GE AU - Gage, K L AU - Eisen, R J AD - Centers for Disease Control and Prevention (CDC), National Center for Zoonotic, Vector-Borne and Enteric Diseases, Division of Vector-Borne Infectious Diseases, 3150 Rampart Road, Foothills Campus, Fort Collins, CO 80522, USA, hebrown@cdc.gov Y1 - 2010/01// PY - 2010 DA - Jan 2010 VL - 82 IS - 1 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts A: Industrial & Applied Microbiology KW - Temperature effects KW - Data processing KW - Plague KW - Precipitation KW - Seasonal variations KW - Models KW - A 01450:Environmental Pollution & Waste Treatment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21310162?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Climatic+Predictors+of+the+Intra-+and+Inter-Annual+Distributions+of+Plague+Cases+in+New+Mexico+Based+on+29+Years+of+Animal-Based+Surveillance+Data&rft.au=Brown%2C+HE%3BEttestad%2C+P%3BReynolds%2C+P+J%3BBrown%2C+T+L%3BHatton%2C+E+S%3BHolmes%2C+J+L%3BGlass%2C+GE%3BGage%2C+K+L%3BEisen%2C+R+J&rft.aulast=Brown&rft.aufirst=HE&rft.date=2010-01-01&rft.volume=82&rft.issue=1&rft.spage=&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Temperature effects; Data processing; Precipitation; Plague; Seasonal variations; Models ER - TY - JOUR T1 - Demographic risk factors of pulmonary colonization by non-tuberculous mycobacteria AN - 21286099; 11810471 AB - SETTING: British Columbia (BC), Canada. OBJECTIVE: To determine the risk factors for pulmonary colonization by non-tuberculous mycobacteria (NTM). DESIGN: Retrospective study of subjects colonized by NTM from 1990 to 2006. Subjects without mycobacterial disease and with at least three negative cultures served as controls. RESULTS: Mycobacterium avium complex (MAC) species were the most common NTM. Risk factors of colonization included age .60 years (aOR 2.3), female sex (aOR 1.2), residency in Canada for at least 10 years (aOR 3.8), Canadian-born aboriginal (aOR 1.8), and Canadian-born non-aboriginal (aOR 1.4). Predictors of MAC colonization included White race (aOR 1.6) and residency in Canada for at least 10 years, which was the strongest predictor (aOR 6.7). Aboriginal origin was associated with non-MAC colonization (aOR 1.8), and Canadian-born people from the East/South-East Asian ethnic groups were protected from MAC colonization (aOR 0.2), all aOR P < 0.05. CONCLUSION: Older age, female sex, having been born in Canada, long residency in BC and White race predict pulmonary NTM colonization, while Aboriginal origin predicts non-MAC colonization. Further research is needed to identify environmental NTM sources in BC and to determine their relation to colonization and disease. JF - International Journal of Tuberculosis and Lung Disease AU - Hernandez-Garduno, E AU - Elwood, R K AD - BC Center for Disease Control, TB Control, 1063-655 West 12th Ave, Vancouver, BC V5Z 4R4, Canada, eduardo.hernandez@bccdc.ca Y1 - 2010/01// PY - 2010 DA - Jan 2010 SP - 106 EP - 112 PB - International Union Against Tuberculosis and Lung Disease VL - 14 IS - 1 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology; Risk Abstracts KW - Canada, British Columbia KW - demography KW - Age KW - Mycobacterium avium KW - Lung diseases KW - colonization KW - tuberculosis KW - Demography KW - Colonization KW - Lung KW - Risk factors KW - indigenous peoples KW - Geriatrics KW - Tuberculosis KW - Races KW - Ethnic groups KW - Sex KW - J 02400:Human Diseases KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21286099?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Demographic+risk+factors+of+pulmonary+colonization+by+non-tuberculous+mycobacteria&rft.au=Hernandez-Garduno%2C+E%3BElwood%2C+R+K&rft.aulast=Hernandez-Garduno&rft.aufirst=E&rft.date=2010-01-01&rft.volume=14&rft.issue=1&rft.spage=106&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-01-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Demography; Colonization; Age; Risk factors; Lung diseases; Geriatrics; Tuberculosis; Ethnic groups; Races; Sex; demography; tuberculosis; Lung; indigenous peoples; colonization; Mycobacterium avium; Canada, British Columbia ER - TY - JOUR T1 - Tuberculosis in asymptomatic HIV-infected adults with abnormal chest radiographs screened for tuberculosis prevention AN - 21281841; 11810462 AB - BACKGROUND: Isoniazid preventive therapy (IPT) prevents tuberculosis (TB) in people living with HIV (human immunodeficiency virus, PLWH). Symptom screening without chest radiographs (CXRs) was established as the strategy for excluding TB disease among PLWH seeking IPT in Botswana's 2001 pilot project. This strategy was evaluated in 2004-2006 among candidates screened for an IPT clinical trial. METHODS: PLWH referred from clinics and HIV testing centers were screened for TB symptoms. All asymptomatic candidates received CXRs; those with abnormal CXRs were investigated further. RESULTS: Among 2732 asymptomatic candidates screened, 302 (11%) had abnormal CXRs potentially compatible with TB; TB disease was diagnosed in 43 of these 302 (14%), or 43 (1.6%) of the 2732 asymptomatic candidates. While not associated with CD4 lymphocyte counts < 200 cells/mm super(3), TB was associated with a positive tuberculin skin test (relative risk 2.1, 95%CI 1.1-4.0). IPT was initiated in 113 (62%) of 182 asymptomatic PLWH with abnormal CXRs; 8/113 (7%) subsequently developed TB, and 7/8 (88%) successfully completed anti-tuberculosis treatment. CONCLUSIONS: The prevalences of abnormal CXRs and TB were respectively 2.6- and 8.9-fold higher among asymptomatic PLWH screened for the trial than in the pilot. A cost-effectiveness analysis is needed to determine whether the benefits of symptom screening alone are offset by the risk of inducing INH resistance by excluding CXRs during screening. JF - International Journal of Tuberculosis and Lung Disease AU - Agizew, T B AU - Arwady, MA AU - Yoon, J C AU - Nyirenda, S AU - Mosimaneotsile, B AU - Tedla, Z AU - Motsamai, O AU - Kilmarx, PH AU - Wells, C D AU - Samandari, T AD - Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, 6100 Clifton Road NE, MS E-10, Atlanta, GA 30333, USA, tts0@cdc.gov Y1 - 2010/01// PY - 2010 DA - Jan 2010 SP - 45 EP - 51 VL - 14 IS - 1 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts; Risk Abstracts KW - Risk assessment KW - Mycobacterium KW - Lymphocytes KW - Chest KW - clinical trials KW - Clinical trials KW - Cost-benefit analysis KW - CD4 antigen KW - prevention KW - Tuberculosis KW - Isoniazid KW - Cell number KW - Lung diseases KW - Skin tests KW - tuberculosis KW - Lung KW - Human immunodeficiency virus KW - Botswana KW - Tuberculin KW - Radiography KW - V 22360:AIDS and HIV KW - J 02400:Human Diseases KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21281841?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Tuberculosis+in+asymptomatic+HIV-infected+adults+with+abnormal+chest+radiographs+screened+for+tuberculosis+prevention&rft.au=Agizew%2C+T+B%3BArwady%2C+MA%3BYoon%2C+J+C%3BNyirenda%2C+S%3BMosimaneotsile%2C+B%3BTedla%2C+Z%3BMotsamai%2C+O%3BKilmarx%2C+PH%3BWells%2C+C+D%3BSamandari%2C+T&rft.aulast=Agizew&rft.aufirst=T&rft.date=2010-01-01&rft.volume=14&rft.issue=1&rft.spage=45&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-01-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Human immunodeficiency virus; Mycobacterium; Botswana; tuberculosis; clinical trials; Lung; prevention; Cost-benefit analysis; Lymphocytes; Tuberculosis; Radiography; Clinical trials; Chest; Cell number; Skin tests; Isoniazid; Tuberculin; Risk assessment; CD4 antigen; Lung diseases ER - TY - JOUR T1 - Quality Assurance of Rapid Diagnostic Tests for Malaria in Routine Patient Care in Rural Tanzania AN - 21276737; 11847946 AB - Histidine-rich protein II (HRP2)-based malaria rapid diagnostic tests (RDTs) have shown high sensitivity and specificity for detecting Plasmodium falciparum malaria in a variety of study settings. However, RDTs are susceptible to heat and humidity and variation in individual performance, which may affect their use in field settings. We evaluated sensitivity and specificity of RDTs during routine use for malaria case management in peripheral health facilities. From December 2007 to October 2008, HRP2-based ParaHIT-f RDTs were introduced in 12 facilities without available microscopy in Rufiji District, Tanzania. Health workers received a single day of instruction on how to perform an RDT and thick blood smear. Job aids, Integrated Management of Childhood Illness guidelines, and national malaria treatment algorithms were reviewed. For quality assurance (QA), thick blood smears for reference microscopy were collected for 2 to 3 days per week from patients receiving RDTs; microscopy was not routinely performed at the health facilities. Slides were stained and read centrally within 72 hours of collection by a reference microscopist. When RDT and blood smear results were discordant, blood smears were read by additional reference microscopists blinded to earlier results. Facilities were supervised monthly by the district laboratory supervisor or a member of the study team. Ten thousand six hundred fifty (10,650) patients were tested with RDTs, and 51.5% (5,488/10,650) had a positive test result. Blood smear results were available for 3,914 patients, of whom 40.1% (1,577/3,914) were positive for P.falciparum malaria. Overall RDT sensitivity was 90.7% (range by facility 85.7-96.5%) and specificity was 73.5% (range 50.0-84.3%). Sensitivity increased with increasing parasite density. Successful implementation of RDTs was achieved in peripheral health facilities with adequate training and supervision. Quality assurance is essential to the adequate performance of any laboratory test. Centralized staining and reading of blood smears provided useful monitoring of RDT performance. However, this level of QA may not be sustainable nationwide. JF - American Journal of Tropical Medicine and Hygiene AU - McMorrow, M L AU - Masanja, MI AU - Kahigwa, E AU - Abdulla, SMK AU - Kachur, S P AD - Malaria Branch, Division of Parasitic Diseases, Centers for Disease Control and Prevention, 4770 Buford Highway, Mailstop F-22, Atlanta, GA 30341, USA, mmcmorrow@cdc.gov PY - 2010 SP - 151 EP - 155 VL - 82 IS - 1 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts C: Algology, Mycology & Protozoology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Parasites KW - Human diseases KW - Tanzania KW - Quality assurance KW - Algorithms KW - Humidity KW - Malaria KW - Plasmodium falciparum KW - Children KW - Public health KW - Blood KW - Workers KW - Heat KW - Quality control KW - Tests KW - Microscopy KW - Language KW - Hygiene KW - K 03400:Human Diseases KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21276737?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Quality+Assurance+of+Rapid+Diagnostic+Tests+for+Malaria+in+Routine+Patient+Care+in+Rural+Tanzania&rft.au=McMorrow%2C+M+L%3BMasanja%2C+MI%3BKahigwa%2C+E%3BAbdulla%2C+SMK%3BKachur%2C+S+P&rft.aulast=McMorrow&rft.aufirst=M&rft.date=2010-01-01&rft.volume=82&rft.issue=1&rft.spage=151&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - Last updated - 2016-01-06 N1 - SubjectsTermNotLitGenreText - Parasites; Human diseases; Tests; Quality assurance; Malaria; Hygiene; Public health; Workers; Blood; Heat; Quality control; Microscopy; Algorithms; Humidity; Language; Children; Plasmodium falciparum; Tanzania ER - TY - JOUR T1 - Utility of a Point-of-Care Malaria Rapid Diagnostic Test for Excluding Malaria as the Cause of Fever among HIV-Positive Adults in Rural Rakai, Uganda AN - 21276718; 11847944 AB - We compared results of a malaria rapid diagnostic test (Binax Now+ Malaria, Binax-M, Inverness Medical Innovations, Inc., Waltham, MA) performed at rural mobile clinics in Uganda by clinicians evaluating febrile adult HIV patients to thick smear evaluated at a central laboratory by trained microscopists. Two hundred forty-six samples were analyzed, including 14 (5.7%) which were thick-smear positive for falciparum malaria. Sensitivity of Binax-M compared with thick smear was 85.7% (95% CI: 57.2-98.2), specificity 97.8% (95% CI: 94.9-99.3), positive and negative predictive values were 70.6% (95% CI: 44.0-89.7) and 99.1% (95% CI: 96.8-99.9), respectively. The rapid diagnostic test accurately ruled malaria "in or out" at the point-of-care, facilitating appropriate clinical management and averting unnecessary anti-malarial therapy. JF - American Journal of Tropical Medicine and Hygiene AU - Mills, LA AU - Kagaayi, J AU - Nakigozi, G AU - Galiwango, R M AU - Ouma, J AU - Shott, J P AU - Ssempijja, V AU - Gray, R H AU - Wawer, MJ AU - Serwadda, D AU - Quinn, T C AU - Reynolds, S J AD - Division of Infectious Diseases, Johns Hopkins Medical Institutions, 1830 East Monument Street, Room #401, Baltimore, MD 21287, USA, LMills@ke.cdc.gov Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 145 EP - 147 VL - 82 IS - 1 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts C: Algology, Mycology & Protozoology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Fever KW - Human diseases KW - Human immunodeficiency virus KW - Therapy KW - Uganda KW - Malaria KW - Hygiene KW - Public health KW - K 03340:Effects of Physical & Chemical Factors KW - Q1 08484:Species interactions: parasites and diseases KW - J 02400:Human Diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21276718?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Utility+of+a+Point-of-Care+Malaria+Rapid+Diagnostic+Test+for+Excluding+Malaria+as+the+Cause+of+Fever+among+HIV-Positive+Adults+in+Rural+Rakai%2C+Uganda&rft.au=Mills%2C+LA%3BKagaayi%2C+J%3BNakigozi%2C+G%3BGaliwango%2C+R+M%3BOuma%2C+J%3BShott%2C+J+P%3BSsempijja%2C+V%3BGray%2C+R+H%3BWawer%2C+MJ%3BSerwadda%2C+D%3BQuinn%2C+T+C%3BReynolds%2C+S+J&rft.aulast=Mills&rft.aufirst=LA&rft.date=2010-01-01&rft.volume=82&rft.issue=1&rft.spage=145&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Human diseases; Therapy; Malaria; Hygiene; Public health; Fever; Human immunodeficiency virus; Uganda ER - TY - JOUR T1 - Sodium Dichloroisocyanurate Tablets for Routine Treatment of Household Drinking Water in Periurban Ghana: A Randomized Controlled Trial AN - 21260567; 11847922 AB - We conducted a randomized, placebo-controlled, triple-blinded trial to determine the health impact of daily use of sodium dichloroisocyanurate (NaDCC) tablets for household drinking water treatment in periurban Ghana. We randomized 240 households (3,240 individuals) to receive either NaDCC or placebo tablets. All households received a 20-liter safe water storage vvessel. Over 12 weeks, 446 diarrhea episodes (2.2%) occurred in intervention and 404 (2.0%) in control households (P = 0.38). Residual free chlorine levels indicated appropriate tablet use. Escherichia coli was found in stored water at baseline in 96% of intervention and 88% of control households and at final evaluation in 8% of intervention and 54% of control households (P = 0.002). NaDCC use did not prevent diarrhea but improved water quality. Diarrhea rates were low and water quality improved in both groups. Safe water storage vessels may have been protective. A follow-up health impact study of NaDCC tablets is warranted. JF - American Journal of Tropical Medicine and Hygiene AU - Jain, S AU - Sahanoon, OK AU - Blanton, E AU - Schmitz, A AU - Wannemuehler, KA AU - Hoekstra, R M AU - Quick, R E AD - Enteric Diseases Epidemiology Branch, Centers for Disease Control and Prevention, 1600 Clifton Road, MS A-38, Atlanta, GA 30333, USA, bwc8@cdc.gov Y1 - 2010/01// PY - 2010 DA - Jan 2010 VL - 82 IS - 1 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts B: Bacteriology KW - Diarrhea KW - sodium dichloroisocyanurate KW - Escherichia coli KW - Tablets KW - Chlorine KW - Water quality KW - Drinking water KW - J 02450:Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21260567?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Sodium+Dichloroisocyanurate+Tablets+for+Routine+Treatment+of+Household+Drinking+Water+in+Periurban+Ghana%3A+A+Randomized+Controlled+Trial&rft.au=Jain%2C+S%3BSahanoon%2C+OK%3BBlanton%2C+E%3BSchmitz%2C+A%3BWannemuehler%2C+KA%3BHoekstra%2C+R+M%3BQuick%2C+R+E&rft.aulast=Jain&rft.aufirst=S&rft.date=2010-01-01&rft.volume=82&rft.issue=1&rft.spage=&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Diarrhea; sodium dichloroisocyanurate; Tablets; Chlorine; Drinking water; Water quality; Escherichia coli ER - TY - JOUR T1 - Implications of using hierarchical and six degree-of-freedom models for normal gait analyses AN - 21230894; 11793080 AB - Hierarchical biomechanical models (conventional gait model, CGM) are attractive because of simple data collection demands, yet they are susceptible to errors that are theoretically better controlled using six degree-of-freedom models that track body segments independently (OPT1). We wished to compare gait variables obtained with these models. Twenty-five normal children walked while wearing a hybrid marker configuration, permitting identical strides to be analyzed using CGM and OPT1. Kinematics and ground reaction forces were obtained using a common motion capture system. CGM and OPT1 were implemented in Visual3D software, where inverse dynamics provided 20 clinically relevant gait variables (joint angles, moments and powers). These were compared between models using dependent t-tests (Bonferroni-adjusted alpha of 0.0025), and ensemble averages. We hypothesized that OPT1 would provide data similar to CGM in the sagittal plane, and different from CGM in coronal and transverse planes. Six variables were significantly different in the sagittal plane, suggesting that CGM produced a more extended lower extremity; this was explained by a posterior bias to the lateral knee marker during knee flexion, as a result of skin movement artifact. No significant differences were found in coronal plane variables. Four variables were significantly different in the transverse plane. Ensemble averages were comparable between models. For normal children, biomechanical interpretations based upon these tested variables are unlikely to change due to independent segment tracking alone (CGM vs. OPT1). Additional differences may appear due to pathology, and when segment reference frames are changed from those used in CGM to reflect individual anatomy. JF - Gait & Posture AU - Buczek, Frank L AU - Rainbow, Michael J AU - Cooney, Kevin M AU - Walker, Matthew R AU - Sanders, James O AD - National Institute for Occupational Safety & Health, Morgantown, WV, USA, fbuczek@cdc.gov Y1 - 2010/01// PY - 2010 DA - Jan 2010 SP - 57 EP - 63 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 31 IS - 1 SN - 0966-6362, 0966-6362 KW - Physical Education Index KW - Skin KW - Analysis KW - Knees KW - Legs KW - Children KW - Gait KW - Movement KW - Biomechanics KW - Anatomy KW - PE 100:Kinesiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21230894?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Gait+%26+Posture&rft.atitle=Implications+of+using+hierarchical+and+six+degree-of-freedom+models+for+normal+gait+analyses&rft.au=Buczek%2C+Frank+L%3BRainbow%2C+Michael+J%3BCooney%2C+Kevin+M%3BWalker%2C+Matthew+R%3BSanders%2C+James+O&rft.aulast=Buczek&rft.aufirst=Frank&rft.date=2010-01-01&rft.volume=31&rft.issue=1&rft.spage=57&rft.isbn=&rft.btitle=&rft.title=Gait+%26+Posture&rft.issn=09666362&rft_id=info:doi/10.1016%2Fj.gaitpost.2009.08.245 LA - English DB - Physical Education Index N1 - Date revised - 2010-01-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Gait; Analysis; Biomechanics; Knees; Children; Movement; Anatomy; Skin; Legs DO - http://dx.doi.org/10.1016/j.gaitpost.2009.08.245 ER - TY - JOUR T1 - Two-dimensional biomechanical model for estimating strength of youth and adolescents for manual material handling tasks AN - 21161924; 11183885 AB - Youth and adolescents are routinely engaged in manual material handling (MMH) tasks that may exceed their strength capability to perform the task and may place them at excessive risk for musculoskeletal disorders. This paper reports on a two-dimensional biomechanical model that was developed to assess MMH tasks performed by youth 3-21 years of age. The model uses age, gender, posture of the youth performing the MMH activity, and weight of the load handled as input, and provides an estimate of the strength demands of the task and spinal disc compression and shear force resulting from the activity as output. The model can be used to assess whether a specific MMH task exceeds the strength demands for youth of certain ages or genders, which of the internal muscle strengths are most affected, and provides information about the estimated spinal disc compression and shear forces on the spine as a result of the specified MMH task. These results would be helpful in deciding whether a task is appropriate for a youth to perform or whether a certain task modification may be sufficient in reducing the physical demands to a level acceptable for a youth of certain age and gender. JF - Applied Ergonomics AU - Waters, Thomas R AU - Garg, Arun AD - National Institute for Occupational Safety and Health, Division of Applied Research and Technology, 4676 Columbia Parkway, 45226 Cincinnati, OH, USA, trw1@cdc.gov Y1 - 2010/01// PY - 2010 DA - Jan 2010 SP - 1 EP - 7 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 41 IS - 1 SN - 0003-6870, 0003-6870 KW - Health & Safety Science Abstracts; Risk Abstracts KW - Age KW - Materials handling KW - Ergonomics KW - Adolescents KW - spine KW - biomechanics KW - musculoskeletal system KW - Gender KW - posture KW - R2 23080:Industrial and labor KW - H 10000:Ergonomics/Human Factors UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21161924?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+Ergonomics&rft.atitle=Two-dimensional+biomechanical+model+for+estimating+strength+of+youth+and+adolescents+for+manual+material+handling+tasks&rft.au=Waters%2C+Thomas+R%3BGarg%2C+Arun&rft.aulast=Waters&rft.aufirst=Thomas&rft.date=2010-01-01&rft.volume=41&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Applied+Ergonomics&rft.issn=00036870&rft_id=info:doi/10.1016%2Fj.apergo.2009.02.006 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-11-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Age; Gender; Adolescents; Materials handling; biomechanics; musculoskeletal system; Ergonomics; posture; spine DO - http://dx.doi.org/10.1016/j.apergo.2009.02.006 ER - TY - JOUR T1 - Long-term follow-up of monoclonal B-cell lymphocytosis detected in environmental health studies? AN - 1468377790; 16714653 AB - Background: Four individuals in whom Monoclonal B cell Lymphocytosis (MBL) had been previously detected were evaluated for the fourth time after 15-18 years since initial testing. All four were environmental health study participants without hematologic malignancies who had elevated absolute B cell counts at initial testing. Methods: The current laboratory evaluation included complete blood counts, lymphocyte immunophenotypes, immunoglobulin heavy-chain variable (IGHV) gene mutation status, and serum tests for monoclonal immunoglobulins and free light chains. Results from this evaluation were compared with those from the three previous evaluations. Clinical status was assessed by reviewing medical records. Results: B-cell clones with phenotypic characteristics of the original MBL clone were detected in three of the four individuals. Since the last evaluation in 2003, one participant who had a clinical diagnosis of Waldenstrom's Macroglobulinemia had developed a diffuse large cell lymphoma and was treated. Another participant continued to show a decline in lymphocyte and B cell counts, reaching clinical lymphocytopenia and B cell lymphopenia. The MBL clone was still detectable. The remaining two participants had stable blood counts and MBL phenotypes. Neither had been diagnosed with a hematologic malignancy. However, molecular analysis revealed clonal changes in both: one showed a marked decline in the percentage of somatically-mutated B cells, and the other showed a clonal transition from IGHV3-13 to IGHV4-34. Conclusions: A diversity of clonal evolution was observed in these MBL cases. These observations suggest that long-term follow-up studies using standardized MBL subcategories are essential to understanding B-cell pathobiology and optimizing clinical management. Published 2010 Wiley-Liss, Inc. JF - Cytometry Part B AU - Marti, Gerald E AU - Shim, Youn K AU - Albitar, Maher AU - Middleton, Dan AU - Abbasi, Fatima AU - Anderson, Ayana AU - Vogt, Robert F AD - Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, yshim@cdc.gov Y1 - 2010 PY - 2010 DA - 2010 SP - S83 EP - S90 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 78B IS - S1 SN - 1552-4957, 1552-4957 KW - Immunology Abstracts; Health & Safety Science Abstracts KW - Waldenstrom's macroglobulinemia KW - Light chains KW - medical records KW - Lymphocytes B KW - Point mutation KW - Lymphopenia KW - Environmental health KW - Lymphocytes KW - Cytometry KW - Blood KW - Malignancy KW - Lymphocytosis KW - Standards KW - lymphoma KW - Mutation KW - Lymphoma KW - Evolution KW - Immunoglobulins KW - F:0695 KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1468377790?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cytometry+Part+B&rft.atitle=Long-term+follow-up+of+monoclonal+B-cell+lymphocytosis+detected+in+environmental+health+studies%3F&rft.au=Marti%2C+Gerald+E%3BShim%2C+Youn+K%3BAlbitar%2C+Maher%3BMiddleton%2C+Dan%3BAbbasi%2C+Fatima%3BAnderson%2C+Ayana%3BVogt%2C+Robert+F&rft.aulast=Marti&rft.aufirst=Gerald&rft.date=2010-01-01&rft.volume=78B&rft.issue=S1&rft.spage=S83&rft.isbn=&rft.btitle=&rft.title=Cytometry+Part+B&rft.issn=15524957&rft_id=info:doi/10.1002%2Fcyto.b.20522 L2 - http://onlinelibrary.wiley.com/doi/10.1002/cyto.b.20522/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-12-01 N1 - Last updated - 2013-12-16 N1 - SubjectsTermNotLitGenreText - Light chains; Waldenstrom's macroglobulinemia; Lymphocytes B; medical records; Point mutation; Lymphopenia; Cytometry; Blood; Malignancy; Lymphocytosis; Lymphoma; Evolution; Immunoglobulins; Environmental health; Standards; Lymphocytes; Mutation; lymphoma DO - http://dx.doi.org/10.1002/cyto.b.20522 ER -