TY - JOUR T1 - Increasing the dose of television advertising in a national antismoking media campaign: results from a randomised field trial AN - 1859482102; PQ0003994435 AB - BackgroundWhile antismoking media campaigns have demonstrated effectiveness, less is known about the country-level effects of increased media dosing. The 2012 US Tips From Former Smokers (Tips) campaign generated approximately 1.6 million quit attempts overall; however, the specific dose-response from the campaign was only assessed by self-report.ObjectiveAssess the impact of higher ad exposure during the 2013 Tips campaign on quit-related behaviours and intentions, campaign awareness, communication about campaign, and disease knowledge.MethodsA 3-month national media buy was supplemented within 67 (of 190) randomly selected local media markets. Higher-dose markets received media buys 3 times that of standard-dose markets. We compared outcomes of interest using data collected via web-based surveys from nationally representative, address-based probability samples of 5733 cigarette smokers and 2843 non-smokers.ResultsIn higher-dose markets, 87.2% of smokers and 83.9% of non-smokers recalled television campaign exposure versus 75.0% of smokers and 73.9% of non-smokers in standard-dose markets. Among smokers overall, the relative quit attempt rate was 11% higher in higher-dose markets (38.8% vs 34.9%; p<0.04). The higher-dose increase was larger in African-Americans (50.9% vs 31.8%; p<0.01). Smokers in higher-dose markets without a mental health condition, with a chronic health condition, or with only some college education made quit attempts at a higher rate than those in standard-dose markets. Non-smokers in higher-dose markets were more likely to talk with family or friends about smoking dangers (43.1% vs 35.7%; p<0.01) and had greater knowledge of smoking-related diseases.ConclusionsThe US 2013 Tips antismoking media campaign compared standard and higher doses by randomisation of local media markets. Results demonstrate the effectiveness of a higher dose for engaging non-smokers and further increasing quit attempts among smokers, especially African-Americans. JF - Tobacco Control AU - McAfee, Tim AU - Davis, Kevin C AU - Shafer, Paul AU - Patel, Deesha AU - Alexander, Robert AU - Bunnell, Rebecca AD - Office on Smoking and Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, , Atlanta, Georgia, USA Y1 - 2017/01/17/ PY - 2017 DA - 2017 Jan 17 SP - 19 EP - 28 PB - BMJ Publishing Group Ltd. VL - 26 IS - 1 SN - 0964-4563, 0964-4563 KW - Toxicology Abstracts KW - Social marketing KW - Media KW - Cessation KW - Advertising and Promotion UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1859482102?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Tobacco+Control&rft.atitle=Increasing+the+dose+of+television+advertising+in+a+national+antismoking+media+campaign%3A+results+from+a+randomised+field+trial&rft.au=McAfee%2C+Tim%3BDavis%2C+Kevin+C%3BShafer%2C+Paul%3BPatel%2C+Deesha%3BAlexander%2C+Robert%3BBunnell%2C+Rebecca&rft.aulast=McAfee&rft.aufirst=Tim&rft.date=2017-01-17&rft.volume=26&rft.issue=1&rft.spage=19&rft.isbn=&rft.btitle=&rft.title=Tobacco+Control&rft.issn=09644563&rft_id=info:doi/10.1136%2Ftobaccocontrol-2015-052517 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2017-01-01 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1136/tobaccocontrol-2015-052517 ER - TY - JOUR T1 - Unhealthy environments, unhealthy consequences: Experienced homonegativity and HIV infection risk among young men who have sex with men AN - 1841839704 AB - Unfavourable social environments can negatively affect the health of gay, bisexual, and other men who have sex with men (MSM). We described how experienced homonegativity - negative perceptions and treatment that MSM encounter due to their sexual orientations - can increase HIV vulnerability among young MSM. Participants (n = 44) were young MSM diagnosed with HIV infection during January 2006-June 2009. All participants completed questionnaires that assessed experienced homonegativity and related factors (e.g. internalised homonegativity). We focus this analysis on qualitative interviews in which a subset of participants (n = 28) described factors that they perceived to have placed them at risk for HIV infection. Inductive content analysis identified themes within qualitative interviews, and we determined the prevalence of homonegativity and related factors using questionnaires. In qualitative interviews, participants reported that young MSM commonly experienced homonegativity. They described how homonegativity generated internalised homonegativity, HIV stigma, silence around homosexuality, and forced housing displacement. These factors could promote HIV risk. Homonegative experiences were more common among young Black (vs. non-Black) MSM who completed questionnaires. Results illustrate multiple pathways through which experienced homonegativity may increase HIV vulnerability among young MSM. Interventions that target homonegativity might help to reduce the burden of HIV within this population. JF - Global Public Health AU - Jeffries, William L, IV AU - Gelaude, Deborah J AU - Torrone, Elizabeth A AU - Gasiorowicz, Mari AU - Oster, Alexandra M AU - Spikes, Pilgrim S, Jr AU - McCree, Donna Hubbard AU - Bertolli, Jeanne AD - Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA; Epidemic Intelligence Service, Division of Scientific Education and Professional Development, Center for Surveillance, Epidemiology, and Laboratory Services, Centers for Disease Control and Prevention, Atlanta, GA, USA ; Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA ; Epidemic Intelligence Service, Division of Scientific Education and Professional Development, Center for Surveillance, Epidemiology, and Laboratory Services, Centers for Disease Control and Prevention, Atlanta, GA, USA; Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA ; Division of Public Health, Wisconsin Department of Health Services, Madison, WI, USA ; Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA; Epidemic Intelligence Service, Division of Scientific Education and Professional Development, Center for Surveillance, Epidemiology, and Laboratory Services, Centers for Disease Control and Prevention, Atlanta, GA, USA Y1 - 2017/01// PY - 2017 DA - Jan 2017 SP - 116 EP - 129 CY - Abingdon PB - Taylor & Francis Ltd. VL - 12 IS - 1 SN - 1744-1692 KW - Public Health And Safety KW - Homonegativity KW - men who have sex with men KW - HIV KW - Health risk assessment KW - Human immunodeficiency virus--HIV KW - Infections KW - Questionnaires KW - Mens health KW - Homosexuality KW - At risk KW - Bisexuals KW - Vulnerability KW - Housing KW - Stigmatization KW - Displacement KW - Infection KW - Men KW - Young men KW - Content analysis KW - Human Immunodeficiency Virus KW - Qualitative Methods KW - Stigma KW - Sex KW - Risk KW - Bisexuality KW - Males KW - Treatment KW - Content Analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1841839704?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Global+Public+Health&rft.atitle=Unhealthy+environments%2C+unhealthy+consequences%3A+Experienced+homonegativity+and+HIV+infection+risk+among+young+men+who+have+sex+with+men&rft.au=Jeffries%2C+William+L%2C+IV%3BGelaude%2C+Deborah+J%3BTorrone%2C+Elizabeth+A%3BGasiorowicz%2C+Mari%3BOster%2C+Alexandra+M%3BSpikes%2C+Pilgrim+S%2C+Jr%3BMcCree%2C+Donna+Hubbard%3BBertolli%2C+Jeanne&rft.aulast=Jeffries&rft.aufirst=William&rft.date=2017-01-01&rft.volume=12&rft.issue=1&rft.spage=116&rft.isbn=&rft.btitle=&rft.title=Global+Public+Health&rft.issn=17441692&rft_id=info:doi/10.1080%2F17441692.2015.1062120 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA); PAIS Index N1 - Copyright - This work was authored as part of the Contributor's official duties as an Employee of the United States Government and is therefore a work of the United States Government. In accordance with 17 U.S.C. 105, no copyright protection is available for such works under U.S. Law. N1 - Last updated - 2017-01-26 DO - http://dx.doi.org/10.1080/17441692.2015.1062120 ER - TY - JOUR T1 - Association of School District Policies for Radon Testing and Radon-Resistant New Construction Practices with Indoor Radon Zones. AN - 1852689424; 27983613 AB - Radon is a naturally occurring, colorless, odorless, and tasteless radioactive gas. Without testing, its presence is unknown. Using nationally representative data from the 2012 School Health Policies and Practices Study, we examined whether the prevalence of school district policies for radon testing and for radon-resistant new construction practices varied by district location in relation to the U.S. Environmental Protection Agency Map of Radon Zones. Among school districts located in counties with high predicted average indoor radon, 42.4% had policies for radon testing and 37.5% had policies for radon-resistant new construction practices. These findings suggest a critical need for improved awareness among policy makers regarding potential radon exposure for both students and school staff. JF - International journal of environmental research and public health AU - Foster, Stephanie AU - Everett Jones, Sherry AD - Agency for Toxic Substances and Disease Registry, Atlanta, GA 30341, USA. slfoster@cdc.gov. ; Centers for Disease Control and Prevention, Atlanta, GA 30329, USA. severettjones@cdc.gov. Y1 - 2016/12/13/ PY - 2016 DA - 2016 Dec 13 VL - 13 IS - 12 KW - schools KW - school district KW - testing KW - radon-resistant new construction KW - policy KW - radon UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1852689424?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+journal+of+environmental+research+and+public+health&rft.atitle=Association+of+School+District+Policies+for+Radon+Testing+and+Radon-Resistant+New+Construction+Practices+with+Indoor+Radon+Zones.&rft.au=Foster%2C+Stephanie%3BEverett+Jones%2C+Sherry&rft.aulast=Foster&rft.aufirst=Stephanie&rft.date=2016-12-13&rft.volume=13&rft.issue=12&rft.spage=&rft.isbn=&rft.btitle=&rft.title=International+journal+of+environmental+research+and+public+health&rft.issn=1660-4601&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date created - 2016-12-16 N1 - Date revised - 2017-01-14 N1 - Last updated - 2017-01-19 ER - TY - JOUR T1 - Secondhand smoke exposure at home among one billion children in 21 countries: findings from the Global Adult Tobacco Survey (GATS) AN - 1859490914; PQ0004003238 AB - ObjectiveChildren are vulnerable to secondhand smoke (SHS) exposure because of limited control over their indoor environment. Homes remain the major place where children may be exposed to SHS. Our study examines the magnitude, patterns and determinants of SHS exposure in the home among children in 21 countries (19 low-income and middle-income countries and 2 high-income countries).MethodsGlobal Adult Tobacco Survey (GATS) data, a household survey of people 15years of age or older. Data collected during 2009-2013 were analysed to estimate the proportion of children exposed to SHS in the home. GATS estimates and 2012 United Nations population projections for 2015 were also used to estimate the number of children exposed to SHS in the home.ResultsThe proportion of children younger than 15years of age exposed to SHS in the home ranged from 4.5% (Panama) to 79.0% (Indonesia). Of the approximately one billion children younger than 15years of age living in the 21 countries under study, an estimated 507.74 million were exposed to SHS in the home. China, India, Bangladesh, Indonesia and the Philippines accounted for almost 84.6% of the children exposed to SHS. The prevalence of SHS exposure was higher in countries with higher adult smoking rates and was also higher in rural areas than in urban areas, in most countries.ConclusionsA large number of children were exposed to SHS in the home. Encouraging of voluntary smoke-free rules in homes and cessation in adults has the potential to reduce SHS exposure among children and prevent SHS-related diseases and deaths. JF - Tobacco Control AU - Mbulo, Lazarous AU - Palipudi, Krishna Mohan AU - Andes, Linda AU - Morton, Jeremy AU - Bashir, Rizwan AU - Fouad, Heba AU - Ramanandraibe, Nivo AU - Caixeta, Roberta AU - Dias, Rula Cavaco AU - Wijnhoven, Trudy M A AU - Kashiwabara, Mina AU - Sinha, Dhirendra N AU - Tursan d'Espaignet, Edouard AD - Office on Smoking and Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Office of Smoking and Health, Global Tobacco Control Branch, , Atlanta, Georgia, USA Y1 - 2016/12/11/ PY - 2016 DA - 2016 Dec 11 SP - e95 EP - e100 PB - BMJ Publishing Group Ltd. VL - 25 IS - e2 SN - 0964-4563, 0964-4563 KW - Toxicology Abstracts KW - Secondhand smoke KW - Surveillance and monitoring KW - Global health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1859490914?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Tobacco+Control&rft.atitle=Secondhand+smoke+exposure+at+home+among+one+billion+children+in+21+countries%3A+findings+from+the+Global+Adult+Tobacco+Survey+%28GATS%29&rft.au=Mbulo%2C+Lazarous%3BPalipudi%2C+Krishna+Mohan%3BAndes%2C+Linda%3BMorton%2C+Jeremy%3BBashir%2C+Rizwan%3BFouad%2C+Heba%3BRamanandraibe%2C+Nivo%3BCaixeta%2C+Roberta%3BDias%2C+Rula+Cavaco%3BWijnhoven%2C+Trudy+M+A%3BKashiwabara%2C+Mina%3BSinha%2C+Dhirendra+N%3BTursan+d%27Espaignet%2C+Edouard&rft.aulast=Mbulo&rft.aufirst=Lazarous&rft.date=2016-12-11&rft.volume=25&rft.issue=e2&rft.spage=e95&rft.isbn=&rft.btitle=&rft.title=Tobacco+Control&rft.issn=09644563&rft_id=info:doi/10.1136%2Ftobaccocontrol-2015-052693 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2017-01-01 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1136/tobaccocontrol-2015-052693 ER - TY - JOUR T1 - Lassa and Ebola virus inhibitors identified using minigenome and recombinant virus reporter systems AN - 1850773866; PQ0003897366 AB - Lassa virus (LASV) and Ebola virus (EBOV) infections are important global health issues resulting in significant morbidity and mortality. While several promising drug and vaccine trials for EBOV are ongoing, options for LASV infection are currently limited to ribavirin treatment. A major factor impeding the development of antiviral compounds to treat these infections is the need to manipulate the virus under BSL-4 containment, limiting research to a few institutes worldwide. Here we describe the development of a novel LASV minigenome assay based on the ambisense LASV S segment genome, with authentic terminal untranslated regions flanking a ZsGreen (ZsG) fluorescent reporter protein and a Gaussia princeps luciferase (gLuc) reporter gene. This assay, along with a similar previously established EBOV minigenome, was optimized for high-throughput screening (HTS) of potential antiviral compounds under BSL-2 containment. In addition, we rescued a recombinant LASV expressing ZsG, which, in conjunction with a recombinant EBOV reporter virus, was used to confirm any potential antiviral hits in vitro. Combining an initial screen to identify potential antiviral compounds at BSL-2 containment before progressing to HTS with infectious virus will reduce the amount of expensive and technically challenging BSL-4 containment research. Using these assays, we identified 6-azauridine as having anti-LASV activity, and demonstrated its anti-EBOV activity in human cells. We further identified 2'-deoxy-2'-fluorocytidine as having potent anti-LASV activity, with an EC50 value 10 times lower than that of ribavirin. JF - Antiviral Research AU - Welch, Stephen R AU - Guerrero, Lisa Wiggleton AU - Chakrabarti, Ayan K AU - McMullan, Laura K AU - Flint, Mike AU - Bluemling, Gregory R AU - Painter, George R AU - Nichol, Stuart T AU - Spiropoulou, Christina F AU - Albarino, Cesar G AD - Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, MG G-14, Atlanta, GA, 30329, USA Y1 - 2016/12// PY - 2016 DA - December 2016 SP - 9 EP - 18 PB - Elsevier B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 136 SN - 0166-3542, 0166-3542 KW - Virology & AIDS Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Genomes KW - Mortality KW - Ebolavirus KW - Ribavirin KW - Infection KW - Morbidity KW - 6-Azauridine KW - Lassa virus KW - Antiviral agents KW - Reporter gene KW - Gaussia princeps KW - high-throughput screening KW - Vaccines KW - A 01340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1850773866?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antiviral+Research&rft.atitle=Lassa+and+Ebola+virus+inhibitors+identified+using+minigenome+and+recombinant+virus+reporter+systems&rft.au=Welch%2C+Stephen+R%3BGuerrero%2C+Lisa+Wiggleton%3BChakrabarti%2C+Ayan+K%3BMcMullan%2C+Laura+K%3BFlint%2C+Mike%3BBluemling%2C+Gregory+R%3BPainter%2C+George+R%3BNichol%2C+Stuart+T%3BSpiropoulou%2C+Christina+F%3BAlbarino%2C+Cesar+G&rft.aulast=Welch&rft.aufirst=Stephen&rft.date=2016-12-01&rft.volume=136&rft.issue=&rft.spage=9&rft.isbn=&rft.btitle=&rft.title=Antiviral+Research&rft.issn=01663542&rft_id=info:doi/10.1016%2Fj.antiviral.2016.10.007 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-12-01 N1 - Last updated - 2016-12-21 N1 - SubjectsTermNotLitGenreText - Genomes; Mortality; Antiviral agents; Reporter gene; Ribavirin; high-throughput screening; Vaccines; Infection; 6-Azauridine; Morbidity; Lassa virus; Gaussia princeps; Ebolavirus DO - http://dx.doi.org/10.1016/j.antiviral.2016.10.007 ER - TY - JOUR T1 - Perceived Bonding by Parents Living With HIV and Their Adolescent Children AN - 1847430861 AB - This study examined the associations between parent and adolescent reports of bonding within families and the relationships among reported parental bonding, family conflict and adolescent stress. A total of 118 families from Anhui, China, were recruited for this study. Two family-level bonding scores were constructed: the average of and difference between parent and adolescent bonding scores. Study results indicated that the difference between parent and adolescent bonding reports was associated with higher levels of adolescent daily stress. A negative association was observed between average family-level bonding and the level of parent-reported conflict. Our findings highlight the importance of combining data from both parents and adolescents when studying issues related to family wellbeing. JF - Journal of Research on Adolescence AU - Li, Li AU - Liang, Li-Jung AU - Ji, Guoping AU - Lin, Chunqing AU - Xiao, Yongkang AD - University of California, Los Angeles ; Anhui Provincial Center for Disease Control and Prevention ; University of California, Los Angeles Y1 - 2016/12// PY - 2016 DA - Dec 2016 SP - 880 EP - 888 CY - Hoboken PB - Wiley Subscription Services, Inc. VL - 26 IS - 4 SN - 1050-8392 KW - Psychology KW - Acquired Immune Deficiency Syndrome KW - Parents KW - Family Conflict KW - Family KW - Parent Child Relations KW - Children KW - Adolescents KW - Well Being KW - Stress KW - Parental bonding KW - HIV KW - Family conflict KW - Wellbeing KW - Daily stress KW - 1939:the family and socialization; adolescence & youth UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1847430861?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Research+on+Adolescence&rft.atitle=Perceived+Bonding+by+Parents+Living+With+HIV+and+Their+Adolescent+Children&rft.au=Li%2C+Li%3BLiang%2C+Li-Jung%3BJi%2C+Guoping%3BLin%2C+Chunqing%3BXiao%2C+Yongkang&rft.aulast=Li&rft.aufirst=Li&rft.date=2016-12-01&rft.volume=26&rft.issue=4&rft.spage=880&rft.isbn=&rft.btitle=&rft.title=Journal+of+Research+on+Adolescence&rft.issn=10508392&rft_id=info:doi/10.1111%2Fjora.12236 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA); Sociological Abstracts N1 - Copyright - Journal of Research on Adolescence © 2016 Society for Research on Adolescence N1 - Last updated - 2017-01-17 DO - http://dx.doi.org/10.1111/jora.12236 ER - TY - JOUR T1 - Estimates of CDC-Funded and National HIV Diagnoses: A Comparison by Demographic and HIV-related Factors AN - 1846414857; PQ0003886096 AB - To determine whether CDC-funded HIV testing programs are reaching persons disproportionately affected by HIV infection. The percentage distribution for HIV testing and diagnoses by demographics and transmission risk group (diagnoses only) were calculated using 2013 data from CDC's National HIV Surveillance System and CDC's national HIV testing program data. In 2013, nearly 3.2 million CDC-funded tests were provided to persons aged 13 years and older. Among persons who received a CDC-funded test, 41.1 % were aged 20-29 years; 49.2 % were male, 46.2 % were black/African American, and 56.2 % of the tests were conducted in the South. Compared with the characteristics of all persons diagnosed with HIV in the United States in 2013, among persons diagnosed as a result of CDC-funded tests, a higher percentage were aged 20-29 years (40.3 vs 33.7 %) and black/African American (55.3 vs 46.0 %). CDC-funded HIV testing programs are reaching young people and blacks/African Americans. JF - AIDS and Behavior AU - Krueger, Amy AU - Dietz, Patricia AU - Van Handel, Michelle AU - Belcher, Lisa AU - Johnson, Anna Satcher AD - Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, CDC, 1600 Clifton Road, NE, Mailstop E-59, Atlanta, GA, 30333, USA, akrueger@cdc.gov Y1 - 2016/12// PY - 2016 DA - December 2016 SP - 2961 EP - 2965 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 20 IS - 12 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Demography KW - USA KW - Acquired immune deficiency syndrome KW - Lentivirus KW - Risk factors KW - Retroviridae KW - Infection KW - Ethnic groups KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1846414857?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Estimates+of+CDC-Funded+and+National+HIV+Diagnoses%3A+A+Comparison+by+Demographic+and+HIV-related+Factors&rft.au=Krueger%2C+Amy%3BDietz%2C+Patricia%3BVan+Handel%2C+Michelle%3BBelcher%2C+Lisa%3BJohnson%2C+Anna+Satcher&rft.aulast=Krueger&rft.aufirst=Amy&rft.date=2016-12-01&rft.volume=20&rft.issue=12&rft.spage=2961&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-016-1293-1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-12-01 N1 - Number of references - 16 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Demography; Acquired immune deficiency syndrome; Risk factors; Infection; Ethnic groups; Lentivirus; Retroviridae; USA DO - http://dx.doi.org/10.1007/s10461-016-1293-1 ER - TY - JOUR T1 - Racial/ethnic disparities in self-reported short sleep duration among US-born and foreign-born adults AN - 1818393452 AB - Objective. Racial/ethnic health disparities are infrequently considered by nativity status in the United States, although the immigrant population has practically doubled since 1990. We investigated the modifying role of nativity status (US- vs. foreign-born) on racial/ethnic disparities in short sleep duration (<7 h), which has serious health consequences. Design. Cross-sectional data from 23,505 US-born and 4,326 foreign-born adults aged [greater than or equal to] 18 years from the 2012 National Health Interview Survey and multivariable log-linear regression were used to estimate prevalence ratios (PR) for reporting short sleep duration and their corresponding 95% confidence intervals (CI). Results. After controlling for sociodemographic covariates, short sleep was more prevalent among blacks (PR 1.29, 95% CI: 1.21-1.37), Hispanics (PR 1.18, 95% CI: 1.08, 1.29), and Asians (PR 1.37, 95% CI: 1.16-1.61) than whites among US-born adults. Short sleep was more prevalent among blacks (PR 1.71, 95% CI: 1.38, 2.13) and Asians (PR 1.23, 95% CI: 1.02, 1.47) than whites among the foreign-born. Conclusion. Among both US- and foreign-born adults, blacks and Asians had a higher likelihood of short sleep compared to whites. US-born Hispanics, but not foreign-born Hispanics, had a higher likelihood than their white counterparts. Future research should aim to uncover mechanisms underlying these disparities. JF - Ethnicity and Health AU - Cunningham, Timothy J AU - Wheaton, Anne G AU - Ford, Earl S AU - Croft, Janet B AD - Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA ; Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA Y1 - 2016/12// PY - 2016 DA - Dec 2016 SP - 628 EP - 638 CY - Abingdon PB - Taylor & Francis Ltd. VL - 21 IS - 6 SN - 1355-7858 KW - Public Health And Safety KW - Sleep KW - nativity KW - immigration KW - race KW - ethnicity KW - stress KW - Health Problems KW - Methodology (Data Collection) KW - Ethnicity KW - Racial Differences KW - Elderly KW - Sociodemographic Factors KW - United States--US KW - 2045:sociology of health and medicine; sociology of medicine & health care KW - 6140:illness & health care KW - 6148:problems of minority groups UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1818393452?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocabs&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ethnicity+and+Health&rft.atitle=Racial%2Fethnic+disparities+in+self-reported+short+sleep+duration+among+US-born+and+foreign-born+adults&rft.au=Cunningham%2C+Timothy+J%3BWheaton%2C+Anne+G%3BFord%2C+Earl+S%3BCroft%2C+Janet+B&rft.aulast=Cunningham&rft.aufirst=Timothy&rft.date=2016-12-01&rft.volume=21&rft.issue=6&rft.spage=628&rft.isbn=&rft.btitle=&rft.title=Ethnicity+and+Health&rft.issn=13557858&rft_id=info:doi/10.1080%2F13557858.2016.1179724 LA - English DB - Social Services Abstracts; Sociological Abstracts N1 - Copyright - This work was authored as part of the Contributor's official duties as an Employee of the United States Government and is therefore a work of the United States Government. In accordance with 17 U.S.C. 105, no copyright protection is available for such works under U.S. Law. N1 - Last updated - 2016-11-21 N1 - SubjectsTermNotLitGenreText - United States--US DO - http://dx.doi.org/10.1080/13557858.2016.1179724 ER - TY - JOUR T1 - Efficacy of Chloroquine and Primaquine for the Treatment of Uncomplicated Plasmodium vivax Malaria in Cruzeiro do Sul, Brazil AN - 1850778645; PQ0003910115 AB - We evaluated the efficacy of chloroquine and primaquine on uncomplicated Plasmodium vivax malaria in Cruzeiro do Sul, Brazil, in 2014. Patients > or = 5 years of age with either fever or history of fever, and laboratory-confirmed P. vivax monoinfection received chloroquine (total dose = 25 mg/kg) and primaquine (total dose = 3.5 mg/kg), and were followed up for 168 days (24 weeks). We used microsatellite genotyping to differentiate recurrent infections caused by heterologous parasites from those caused by homologous ones. No new P. vivax episode occurred by Day 28 among 119 enrolled patients, leading to Day 28, with adequate clinical and parasitological response (ACPR) of 100% (95% confidence interval [CI] = 96.7-100%). Twenty-eight P. vivax episodes occurred by Day 168, with uncorrected ACPR of 69.9% (95% CI = 59.5-79.0%). Fifteen of these episodes were caused by either homologous haplotypes or haplotypes that could not be determined. Excluding the 13 recurrent episodes caused by heterologous parasites, Day 168 microsatellite-corrected ACPR was estimated at 81.2% (95% CI = 71.0-89.1%). Chloroquine and primaquine remain efficacious to treat acute uncomplicated P. vivax infection, but moderate recurrence rates were observed within 24 weeks of follow-up. JF - American Journal of Tropical Medicine and Hygiene AU - Negreiros, Suiane AU - Farias, Samela AU - Viana, Giselle Maria Rachid AU - Okoth, Sheila Akinyi AU - Chenet, Stella M AU - de Souza, Thayna Maria Holanda AU - Marchesini, Paola AU - Udhayakumar, Venkatachalam AU - Povoa, Marinete Marins AU - Santelli, Ana Carolina Faria e Silva AU - de Oliveira, Alexandre Macedo AD - Acre State Health Secretariat, Acre State, Brazil, acq7@cdc.gov Y1 - 2016/11// PY - 2016 DA - November 2016 SP - 1061 EP - 1068 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 95 IS - 5 SN - 0002-9637, 0002-9637 KW - ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Historical account KW - Parasites KW - Human diseases KW - Nucleotide sequence KW - Disease control KW - Plasmodium vivax KW - Malaria KW - Genotypes KW - Infection KW - Public health KW - Haplotypes KW - DNA KW - Hygiene KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1850778645?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Efficacy+of+Chloroquine+and+Primaquine+for+the+Treatment+of+Uncomplicated+Plasmodium+vivax+Malaria+in+Cruzeiro+do+Sul%2C+Brazil&rft.au=Negreiros%2C+Suiane%3BFarias%2C+Samela%3BViana%2C+Giselle+Maria+Rachid%3BOkoth%2C+Sheila+Akinyi%3BChenet%2C+Stella+M%3Bde+Souza%2C+Thayna+Maria+Holanda%3BMarchesini%2C+Paola%3BUdhayakumar%2C+Venkatachalam%3BPovoa%2C+Marinete+Marins%3BSantelli%2C+Ana+Carolina+Faria+e+Silva%3Bde+Oliveira%2C+Alexandre+Macedo&rft.aulast=Negreiros&rft.aufirst=Suiane&rft.date=2016-11-01&rft.volume=95&rft.issue=5&rft.spage=1061&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.16-0075 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-12-01 N1 - Last updated - 2016-12-21 N1 - SubjectsTermNotLitGenreText - Parasites; Human diseases; Nucleotide sequence; DNA; Disease control; Malaria; Genotypes; Hygiene; Public health; Historical account; Haplotypes; Infection; Plasmodium vivax DO - http://dx.doi.org/10.4269/ajtmh.16-0075 ER - TY - JOUR T1 - An Outbreak of Fearsome Photos and Headlines: Ebola and Local Newspapers in West Africa AN - 1850777588; PQ0003910100 AB - "Let me get this right, the pilot wants to talk with me in the cockpit?" I asked the flight attendant, as the final passengers boarded the Liberia-bound jet during a refueling stop in west Africa. It was late March 2014, and a small Ebola virus disease (EVD) outbreak had been reported a few weeks earlier in Guinea. The half-read pile of malaria journal articles on my lap provided the flight crew sufficient evidence to conclude there was a "tropical medicine guy" on the flight, just what they needed for their current dilemma. As I walked toward the front of the plane, I had a suspicion what the upcoming topic of discussion would be. JF - American Journal of Tropical Medicine and Hygiene AU - Halsey, Eric S AD - The President's Malaria Initiative, Atlanta, Georgia, ycw8@cdc.gov Y1 - 2016/11// PY - 2016 DA - November 2016 SP - 988 EP - 992 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 95 IS - 5 SN - 0002-9637, 0002-9637 KW - ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Human diseases KW - Ebolavirus KW - Viruses KW - Pilots KW - Malaria KW - Public health KW - Lectures KW - Guinea KW - Photographs KW - Africa KW - Outbreaks KW - Hygiene KW - Q1 08423:Behaviour KW - Q5 08524:Public health, medicines, dangerous organisms KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1850777588?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=An+Outbreak+of+Fearsome+Photos+and+Headlines%3A+Ebola+and+Local+Newspapers+in+West+Africa&rft.au=Halsey%2C+Eric+S&rft.aulast=Halsey&rft.aufirst=Eric&rft.date=2016-11-01&rft.volume=95&rft.issue=5&rft.spage=988&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.16-0245 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-12-01 N1 - Last updated - 2016-12-21 N1 - SubjectsTermNotLitGenreText - Lectures; Human diseases; Photographs; Malaria; Hygiene; Public health; Pilots; Viruses; Outbreaks; Ebolavirus; Guinea; Africa DO - http://dx.doi.org/10.4269/ajtmh.16-0245 ER - TY - JOUR T1 - Partnerships that Facilitate a Refugee's Journey to Wellbeing AN - 1850774525; PQ0003910099 AB - The current global refugee crisis involves 65.3 million persons who have been displaced from their homes or countries of origin. While escaping immediate harm may be their first priority, displaced people go on to face numerous health risks, including trauma and injuries, malnutrition, infectious diseases, exacerbation of existing chronic diseases, and mental health conditions. This crisis highlights the importance of building capacity among health-care providers, scientists, and laboratorians to understand and respond to the health needs of refugees. The November 2016 American Society of Tropical Medicine and Hygiene (ASTMH) conference in Atlanta will feature an interactive exhibit entitled "The Refugee Journey to Wellbeing" and three symposia about refugee health. The symposia will focus on tropical disease challenges in refugee populations, careers in refugee health, and recent experiences of governmental agencies and nongovernmental organizations in responding to the global refugee crisis. We invite ASTMH attendees to attend the exhibit and symposia and consider contributions they could make to improve refugee health through tropical disease research or clinical endeavors. JF - American Journal of Tropical Medicine and Hygiene AU - Marano, Nina AU - Wojno, Abbey E AU - Stauffer, William M AU - Weinberg, Michelle AU - Klosovsky, Alexander AU - Ballew, J Daniel AU - Shetty, Sharmila AU - Cookson, Susan AU - Walker, Patricia AU - Cetron, Martin S AD - Centers for Disease Control and Prevention, Atlanta, Georgia, nbm8@cdc.gov Y1 - 2016/11// PY - 2016 DA - November 2016 SP - 985 EP - 987 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 95 IS - 5 SN - 0002-9637, 0002-9637 KW - ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Conferences KW - Injuries KW - Crises KW - Careers KW - Buildings KW - Refugees KW - Disease transmission KW - Health risks KW - Mental disorders KW - Malnutrition KW - Infectious diseases KW - Priorities KW - USA, Georgia, Atlanta KW - Governments KW - Hygiene KW - Nongovernmental organizations KW - H 11000:Diseases/Injuries/Trauma KW - Q1 08104:Personal KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1850774525?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Partnerships+that+Facilitate+a+Refugee%27s+Journey+to+Wellbeing&rft.au=Marano%2C+Nina%3BWojno%2C+Abbey+E%3BStauffer%2C+William+M%3BWeinberg%2C+Michelle%3BKlosovsky%2C+Alexander%3BBallew%2C+J+Daniel%3BShetty%2C+Sharmila%3BCookson%2C+Susan%3BWalker%2C+Patricia%3BCetron%2C+Martin+S&rft.aulast=Marano&rft.aufirst=Nina&rft.date=2016-11-01&rft.volume=95&rft.issue=5&rft.spage=985&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.16-0657 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-12-01 N1 - Last updated - 2016-12-21 N1 - SubjectsTermNotLitGenreText - Injuries; Infectious diseases; Careers; Governments; Hygiene; Disease transmission; Conferences; Crises; Refugees; Buildings; Health risks; Mental disorders; Malnutrition; Priorities; Nongovernmental organizations; USA, Georgia, Atlanta DO - http://dx.doi.org/10.4269/ajtmh.16-0657 ER - TY - JOUR T1 - A chronological review of experimental infection studies of the role of wild animals and livestock in the maintenance and transmission of Crimean-Congo hemorrhagic fever virus AN - 1846417609; PQ0003845341 AB - This article provides a definitive review of experimental studies of the role of wild animals and livestock in the maintenance and transmission of Crimean-Congo hemorrhagic fever virus (CCHFV), the etiologic agent of Crimean-Congo hemorrhagic fever (CCHF), beginning with the first recognized outbreak of the human disease in Crimea in 1944. Published reports by researchers in the former Soviet Union, Bulgaria, South Africa, and other countries where CCHF has been observed show that CCHFV is maintained in nature in a tick-vertebrate-tick enzootic cycle. Human disease most commonly results from the bite of an infected tick, but may also follow crushing of infected ticks or exposure to the blood and tissues of infected animals during slaughter. Wild and domestic animals are susceptible to infection with CCHFV, but do not develop clinical illness. Vertebrates are important in CCHF epidemiology, as they provide blood meals to support tick populations, transport ticks across wide geographic areas, and transmit CCHFV to ticks and humans during the period of viremia. Many aspects of vertebrate involvement in the maintenance and spread of CCHFV are still poorly understood. Experimental investigations in wild animals and livestock provide important data to aid our understanding of CCHFV ecology. This article is the second in a series of reviews of more than 70 years of research on CCHF, summarizing important findings, identifying gaps in knowledge, and suggesting directions for future research. JF - Antiviral Research AU - Spengler, Jessica R AU - Estrada-Pena, Agustin AU - Garrison, Aura R AU - Schmaljohn, Connie AU - Spiropoulou, Christina F AU - Bergeron, Eric AU - Bente, Dennis A AD - Viral Special Pathogens Branch, Division of High Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA Y1 - 2016/11// PY - 2016 DA - November 2016 SP - 31 EP - 47 PB - Elsevier B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 135 SN - 0166-3542, 0166-3542 KW - Virology & AIDS Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Crimean-Congo hemorrhagic fever KW - Bunyavirus KW - Tick-borne KW - Viral hemorrhagic fever KW - Transmission KW - Experimental infection KW - Data processing KW - Bites KW - Ixodidae KW - Blood meals KW - Bunyaviridae KW - Disease transmission KW - Livestock KW - Domestic animals KW - Blood KW - Epidemiology KW - Reviews KW - Hemorrhagic fever KW - Slaughter KW - Viremia KW - A 01340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1846417609?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antiviral+Research&rft.atitle=A+chronological+review+of+experimental+infection+studies+of+the+role+of+wild+animals+and+livestock+in+the+maintenance+and+transmission+of+Crimean-Congo+hemorrhagic+fever+virus&rft.au=Spengler%2C+Jessica+R%3BEstrada-Pena%2C+Agustin%3BGarrison%2C+Aura+R%3BSchmaljohn%2C+Connie%3BSpiropoulou%2C+Christina+F%3BBergeron%2C+Eric%3BBente%2C+Dennis+A&rft.aulast=Spengler&rft.aufirst=Jessica&rft.date=2016-11-01&rft.volume=135&rft.issue=&rft.spage=31&rft.isbn=&rft.btitle=&rft.title=Antiviral+Research&rft.issn=01663542&rft_id=info:doi/10.1016%2Fj.antiviral.2016.09.013 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-12-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Experimental infection; Data processing; Bites; Blood meals; Livestock; Disease transmission; Blood; Domestic animals; Epidemiology; Reviews; Hemorrhagic fever; Slaughter; Viremia; Ixodidae; Bunyaviridae DO - http://dx.doi.org/10.1016/j.antiviral.2016.09.013 ER - TY - JOUR T1 - Prescription of Pneumocystis Jiroveci Pneumonia Prophylaxis in HIV-Infected Patients AN - 1846415290; PQ0003843920 AB - The US treatment guidelines recommend Pneumocystis jiroveci pneumonia (PCP) prophylaxis for all HIV-infected persons with a CD4 count <200 cells/mm 3 (ie, eligible for PCP prophylaxis). However, some studies suggest PCP prophylaxis may be unnecessary in virally suppressed patients. Using national data of HIV-infected adults receiving medical care in the United States during 2009 to 2012, the authors assessed the weighted percentage of eligible patients who were prescribed PCP prophylaxis and the independent association between PCP prophylaxis prescription and viral suppression. Overall, 81% of eligible patients were prescribed PCP prophylaxis. Virally suppressed eligible patients were less likely to be prescribed PCP prophylaxis (prevalence ratio: 0.84; 95% confidence interval: 0.80-0.89). Although guidelines recommend PCP prophylaxis for all eligible patients, some HIV care providers might not prescribe PCP prophylaxis to virally suppressed patients. Additional data on the risk for PCP among virally suppressed patients are needed to clarify this controversy. JF - Journal of the International Association of Providers of AIDS Care (JIAPAC) AU - Lin, Xia AU - Garg, Shikha AU - Mattson, Christine L AU - Luo, Qingwei AU - Skarbinski, Jacek AD - 1 .Epidemic Intelligence Service, Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA, wft4@cdc.gov Y1 - 2016/11// PY - 2016 DA - November 2016 SP - 455 EP - 458 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU United Kingdom VL - 15 IS - 6 SN - 2325-9574, 2325-9574 KW - Virology & AIDS Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology; Health & Safety Science Abstracts KW - HIV KW - Pneumocystis pneumonia prophylaxis KW - viral suppression KW - Risk assessment KW - USA KW - Acquired immune deficiency syndrome KW - Lentivirus KW - Retroviridae KW - Guidelines KW - Pneumocystis KW - Prophylaxis KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1846415290?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+International+Association+of+Providers+of+AIDS+Care+%28JIAPAC%29&rft.atitle=Prescription+of+Pneumocystis+Jiroveci+Pneumonia+Prophylaxis+in+HIV-Infected+Patients&rft.au=Lin%2C+Xia%3BGarg%2C+Shikha%3BMattson%2C+Christine+L%3BLuo%2C+Qingwei%3BSkarbinski%2C+Jacek&rft.aulast=Lin&rft.aufirst=Xia&rft.date=2016-11-01&rft.volume=15&rft.issue=6&rft.spage=455&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+International+Association+of+Providers+of+AIDS+Care+%28JIAPAC%29&rft.issn=23259574&rft_id=info:doi/10.1177%2F2325957416667486 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-12-01 N1 - Number of references - 14 N1 - Last updated - 2017-02-01 N1 - SubjectsTermNotLitGenreText - Risk assessment; Acquired immune deficiency syndrome; Guidelines; Prophylaxis; Lentivirus; Retroviridae; Pneumocystis; USA DO - http://dx.doi.org/10.1177/2325957416667486 ER - TY - JOUR T1 - Plasmodium falciparum Drug-Resistant Haplotypes and Population Structure in Postearthquake Haiti, 2010 AN - 1850769128; PQ0003935475 AB - Chloroquine (CQ) remains the first-line treatment of malaria in Haiti. Given the challenges of conducting in vivo drug efficacy trials in low-endemic settings like Haiti, molecular surveillance for drug resistance markers is a reasonable approach for detecting resistant parasites. In this study, 349 blood spots were collected from suspected malaria cases in areas in and around Port-au-Prince from March to July 2010. Among them, 121 samples that were Plasmodium falciparum positive by polymerase chain reaction were genotyped for drug-resistant pfcrt, pfdhfr, pfdhps, and pfmdr1 alleles. Among the 108 samples that were successfully sequenced for CQ resistant markers in pfcrt, 107 were wild type (CVMNK), whereas one sample carried a CQ-resistant allele (CVIET). Neutral microsatellite genotyping revealed that the CQ-resistant isolate was distinct from all other samples in this study. Furthermore, the remaining parasite specimens appeared to be genetically distinct from other reported Central and South American populations. JF - American Journal of Tropical Medicine and Hygiene AU - Morton, Lindsay Carol AU - Huber, Curtis AU - Okoth, Sheila Akinyi AU - Griffing, Sean AU - Lucchi, Naomi AU - Ljolje, Dragan AU - Boncy, Jacques AU - Oscar, Roland AU - Townes, David AU - McMorrow, Meredith AU - Chang, Michelle A AU - Udhayakumar, Venkatachalam AU - Barnwell, John W AD - Centers for Disease Control and Prevention, Atlanta, Georgia, wzb3@cdc.gov Y1 - 2016/10// PY - 2016 DA - October 2016 SP - 811 EP - 816 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 95 IS - 4 SN - 0002-9637, 0002-9637 KW - ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Parasites KW - Human diseases KW - Allelles KW - Drug resistance KW - Nucleotide sequence KW - Malaria KW - Plasmodium falciparum KW - Parasite resistance KW - Public health KW - Population genetics KW - Blood KW - Haplotypes KW - Population structure KW - Hygiene KW - Drugs KW - ASW, Caribbean Sea, Greater Antilles, Haiti KW - Q1 08604:Stock assessment and management KW - Q5 08524:Public health, medicines, dangerous organisms KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1850769128?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Plasmodium+falciparum+Drug-Resistant+Haplotypes+and+Population+Structure+in+Postearthquake+Haiti%2C+2010&rft.au=Morton%2C+Lindsay+Carol%3BHuber%2C+Curtis%3BOkoth%2C+Sheila+Akinyi%3BGriffing%2C+Sean%3BLucchi%2C+Naomi%3BLjolje%2C+Dragan%3BBoncy%2C+Jacques%3BOscar%2C+Roland%3BTownes%2C+David%3BMcMorrow%2C+Meredith%3BChang%2C+Michelle+A%3BUdhayakumar%2C+Venkatachalam%3BBarnwell%2C+John+W&rft.aulast=Morton&rft.aufirst=Lindsay&rft.date=2016-10-01&rft.volume=95&rft.issue=4&rft.spage=811&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.16-0214 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-12-01 N1 - Last updated - 2016-12-21 N1 - SubjectsTermNotLitGenreText - Blood; Population genetics; Parasites; Human diseases; Allelles; Nucleotide sequence; Malaria; Hygiene; Public health; Haplotypes; Drug resistance; Population structure; Parasite resistance; Drugs; Plasmodium falciparum; ASW, Caribbean Sea, Greater Antilles, Haiti DO - http://dx.doi.org/10.4269/ajtmh.16-0214 ER - TY - JOUR T1 - Factors predicting double embryo implantation following double embryo transfer in assisted reproductive technology: implications for elective single embryo transfer AN - 1837334443; PQ0003771367 AB - The aim of this study was to identify factors associated with double embryo implantation following double embryo transfer (DET) during assisted reproductive technology (ART) procedures and to evaluate the implications of findings in selecting candidates for elective single embryo transfer (eSET). Factors predicting double embryo implantation, defined as embryo transfers with two or more heartbeats on 6-week ultrasound following DET, were assessed using the US National ART Surveillance System data from 2000 to 2012 (n=1,793,067 fresh, autologous transfers). Adjusted risk ratios (aRRs) were estimated after stratifying by prognosis. Favorable prognosis was defined as first-time ART with supernumerary embryo(s) cryopreserved. Average prognosis was defined as first-time ART without supernumerary embryo(s) cryopreserved, prior unsuccessful ART with supernumerary embryo(s) cryopreserved, or prior ART with previous birth(s) conceived with ART or naturally. Rates and factors associated with double embryo implantation were compared with single embryo implantation following DET among both prognosis groups. Double embryo implantation was positively associated with blastocyst (versus cleavage) transfer in favorable (aRR=1.58 (1.51-1.65)) and average (aRR=1.67 (1.60-1.75)) prognosis groups and negatively associated with age >35 years in both prognosis groups. For average prognosis patients, double embryo implantation was associated with retrieving >10 oocytes (aRR=1.22 (1.18-1.24)). Regardless of prognosis, patients aged 10 oocytes were retrieved may be good candidates for eSET. Physicians may consider using these data to counsel patients on eSET, which would reduce multiple gestations and associated complications. JF - Journal of Assisted Reproduction and Genetics AU - Martin, Caitlin AU - Chang, Jeani AU - Boulet, Sheree AU - Jamieson, Denise J AU - Kissin, Dmitry AD - Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Mailstop F-74, Atlanta, GA, 30341, USA, Caitlin.Martin@emory.edu Y1 - 2016/10// PY - 2016 DA - October 2016 SP - 1343 EP - 1353 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 33 IS - 10 SN - 1058-0468, 1058-0468 KW - Biotechnology and Bioengineering Abstracts; Genetics Abstracts KW - Heart KW - Age KW - Data processing KW - Prognosis KW - Cryopreservation KW - blastocysts KW - Gestation KW - Oocytes KW - Embryo transfer KW - Reproduction KW - Ultrasound KW - Supernumerary KW - W 30910:Imaging KW - G 07880:Human Genetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1837334443?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Assisted+Reproduction+and+Genetics&rft.atitle=Factors+predicting+double+embryo+implantation+following+double+embryo+transfer+in+assisted+reproductive+technology%3A+implications+for+elective+single+embryo+transfer&rft.au=Martin%2C+Caitlin%3BChang%2C+Jeani%3BBoulet%2C+Sheree%3BJamieson%2C+Denise+J%3BKissin%2C+Dmitry&rft.aulast=Martin&rft.aufirst=Caitlin&rft.date=2016-10-01&rft.volume=33&rft.issue=10&rft.spage=1343&rft.isbn=&rft.btitle=&rft.title=Journal+of+Assisted+Reproduction+and+Genetics&rft.issn=10580468&rft_id=info:doi/10.1007%2Fs10815-016-0770-9 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-11-01 N1 - Number of references - 34 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Heart; Age; blastocysts; Data processing; Gestation; Prognosis; Oocytes; Reproduction; Embryo transfer; Ultrasound; Cryopreservation; Supernumerary DO - http://dx.doi.org/10.1007/s10815-016-0770-9 ER - TY - JOUR T1 - Enhanced Genetic Characterization of Influenza A(H3N2) Viruses and Vaccine Effectiveness by Genetic Group, 2014-2015 AN - 1827913141; PQ0003697923 AB - Background. During the 2014-2015 US influenza season, expanded genetic characterization of circulating influenza A(H3N2) viruses was used to assess the impact of the genetic variability of influenza A(H3N2) viruses on influenza vaccine effectiveness (VE). Methods. A novel pyrosequencing assay was used to determine genetic group, based on hemagglutinin (HA) gene sequences, of influenza A(H3N2) viruses from patients enrolled at US Influenza Vaccine Effectiveness Network sites. VE was estimated using a test-negative design comparing vaccination among patients infected with influenza A(H3N2) viruses and uninfected patients. Results. Among 9710 enrollees, 1868 (19%) tested positive for influenza A(H3N2) virus; genetic characterization of 1397 viruses showed that 1134 (81%) belonged to 1 HA genetic group (3C.2a) of antigenically drifted influenza A(H3N2) viruses. Effectiveness of 2014-2015 influenza vaccination varied by influenza A(H3N2) virus genetic group from 1% (95% confidence interval [CI], ?14% to 14%) against illness caused by antigenically drifted influenza A(H3N2) virus group 3C.2a viruses versus 44% (95% CI, 16%-63%) against illness caused by vaccine-like influenza A(H3N2) virus group 3C.3b viruses. Conclusions. Effectiveness of 2014-2015 influenza vaccination varied by genetic group of influenza A(H3N2) virus. Changes in HA genes related to antigenic drift were associated with reduced VE JF - Journal of Infectious Diseases AU - Flannery, Brendan AU - Zimmerman, Richard K AU - Gubareva, Larisa V AU - Garten, Rebecca J AU - Chung, Jessie R AU - Nowalk, Mary Patricia AU - Jackson, Michael L AU - Jackson, Lisa A AU - Monto, Arnold S AU - Ohmit, Suzanne E AD - Influenza Division, Centers for Disease Control and Prevention, bflannery@cdc.gov Y1 - 2016/10/01/ PY - 2016 DA - 2016 Oct 01 SP - 1010 EP - 1019 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 214 IS - 7 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Immunology Abstracts; Health & Safety Science Abstracts KW - influenza KW - genetic characterization KW - pyrosequencing KW - influenza vaccine KW - vaccine effectiveness KW - Influenza KW - Antigenic drift KW - Infectious diseases KW - Hemagglutinins KW - Viruses KW - Vaccines KW - Vaccination KW - V 22310:Genetics, Taxonomy & Structure KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1827913141?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Enhanced+Genetic+Characterization+of+Influenza+A%28H3N2%29+Viruses+and+Vaccine+Effectiveness+by+Genetic+Group%2C+2014-2015&rft.au=Flannery%2C+Brendan%3BZimmerman%2C+Richard+K%3BGubareva%2C+Larisa+V%3BGarten%2C+Rebecca+J%3BChung%2C+Jessie+R%3BNowalk%2C+Mary+Patricia%3BJackson%2C+Michael+L%3BJackson%2C+Lisa+A%3BMonto%2C+Arnold+S%3BOhmit%2C+Suzanne+E&rft.aulast=Flannery&rft.aufirst=Brendan&rft.date=2016-10-01&rft.volume=214&rft.issue=7&rft.spage=1010&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiw181 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-10-01 N1 - Last updated - 2016-11-09 N1 - SubjectsTermNotLitGenreText - Influenza; Antigenic drift; Hemagglutinins; Vaccines; Vaccination; Infectious diseases; Viruses DO - http://dx.doi.org/10.1093/infdis/jiw181 ER - TY - JOUR T1 - Chemoprophylaxis With Oral Emtricitabine and Tenofovir Alafenamide Combination Protects Macaques From Rectal Simian/Human Immunodeficiency Virus Infection AN - 1827913026; PQ0003697928 AB - Tenofovir alafenamide (TAF) is a novel prodrug of tenofovir that efficiently delivers tenofovir diphosphate to lymphoid cells following oral administration. We investigated whether the combination of TAF and emtricitabine (FTC) could prevent simian/human immunodeficiency virus (SHIV) infection in macaques to determine the potential use of TAF for pre-exposure prophylaxis (PrEP) to prevent human immunodeficiency virus infection. Macaques were exposed rectally to SHIV once per week for up to 19 weeks and received saline or FTC/TAF 24 hours before and 2 hours after each virus inoculation. All 6 controls were infected, while the 6 PrEP-treated animals were protected from infection. Our results support the clinical investigation of FTC/TAF for PrEP. JF - Journal of Infectious Diseases AU - Massud, Ivana AU - Mitchell, James AU - Babusis, Darius AU - Deyounks, Frank AU - Ray, Adrian S AU - Rooney, James F AU - Heneine, Walid AU - Miller, Michael D AU - Garcia-Lerma, J Gerardo AD - Laboratory Branch, Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, jng5@cdc.gov Y1 - 2016/10/01/ PY - 2016 DA - 2016 Oct 01 SP - 1058 EP - 1062 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 214 IS - 7 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Immunology Abstracts; Health & Safety Science Abstracts KW - Preexposure prophylaxis KW - tenofovir alafenamide KW - macaques, SHIV KW - Lymphoid cells KW - Rectum KW - Macaca KW - Retroviridae KW - Viruses KW - Simian/human immunodeficiency virus KW - Oral administration KW - tenofovir KW - Infection KW - Infectious diseases KW - Emtricitabine KW - prodrugs KW - Human immunodeficiency virus KW - Prophylaxis KW - Inoculation KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - V 22360:AIDS and HIV UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1827913026?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Chemoprophylaxis+With+Oral+Emtricitabine+and+Tenofovir+Alafenamide+Combination+Protects+Macaques+From+Rectal+Simian%2FHuman+Immunodeficiency+Virus+Infection&rft.au=Massud%2C+Ivana%3BMitchell%2C+James%3BBabusis%2C+Darius%3BDeyounks%2C+Frank%3BRay%2C+Adrian+S%3BRooney%2C+James+F%3BHeneine%2C+Walid%3BMiller%2C+Michael+D%3BGarcia-Lerma%2C+J+Gerardo&rft.aulast=Massud&rft.aufirst=Ivana&rft.date=2016-10-01&rft.volume=214&rft.issue=7&rft.spage=1058&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiw312 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-10-01 N1 - Last updated - 2016-11-09 N1 - SubjectsTermNotLitGenreText - Lymphoid cells; Rectum; prodrugs; Emtricitabine; Oral administration; Inoculation; Prophylaxis; tenofovir; Infection; Infectious diseases; Viruses; Human immunodeficiency virus; Macaca; Retroviridae; Simian/human immunodeficiency virus DO - http://dx.doi.org/10.1093/infdis/jiw312 ER - TY - JOUR T1 - Performance of Dengue Diagnostic Tests in a Single-Specimen Diagnostic Algorithm AN - 1827921892; PQ0003670273 AB - Background.?Anti-dengue virus (DENV) immunoglobulin M (IgM) seroconversion has been the reference standard for dengue diagnosis. However, paired specimens are rarely obtained, and the interval for this testing negates its usefulness in guiding clinical case management. The presence of DENV viremia and appearance of IgM during the febrile phase of dengue provides the framework for dengue laboratory diagnosis by using a single serum specimen. Methods.?Archived paired serum specimens (n = 1234) from patients with laboratory-confirmed dengue from 2005 through 2011 were used to determine the diagnostic performance of real-time reverse transcription polymerase chain reaction (RT-PCR), for detection of DENV serotypes 1-4, and enzyme-linked immunosorbent assays (ELISAs), for detection of DENV nonstructural protein 1 (NS1) antigen and anti-DENV IgM. Results.?During 1-3 days after illness onset, real-time RT-PCR and NS1 antigen testing detected 82%-69% and 90%-84% of cases, respectively, as viremia levels declined, while anti-DENV IgM ELISA detected 5%-41% of cases as antibody appeared. Over the 10-day period of the febrile phase of dengue, the cumulative effect of using these 3 types of tests in a diagnostic algorithm confirmed > or =90% of dengue cases. Conclusions.?The use of molecular or NS1 antigen tests to detect DENV and one to detect anti-DENV IgM in a single serum specimen collected during the first 10 days of illness accurately identified > or =90% of dengue primary and secondary cases. JF - Journal of Infectious Diseases AU - Hunsperger, Elizabeth A AU - Munoz-Jordan, Jorge AU - Beltran, Manuela AU - Colon, Candimar AU - Carrion, Jessica AU - Vazquez, Jesus AU - Acosta, Luz Nereida AU - Medina-Izquierdo, Juan F AU - Horiuchi, Kalanthe AU - Biggerstaff, Brad J AU - Margolis, Harold S AD - Dengue Branch, Division of Vector-Borne Diseases, Centers for Diseases Control and Prevention (CDC), San Juan, Puerto Rico, enh4@cdc.gov Y1 - 2016/09/15/ PY - 2016 DA - 2016 Sep 15 SP - 836 EP - 844 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 214 IS - 6 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Immunology Abstracts; Health & Safety Science Abstracts KW - dengue virus KW - diagnostics KW - enzyme-linked immunoassay KW - dengue virus nonstructural protein 1 (NS1) KW - NS1 antigen detection KW - anti-dengue virus IgM KW - dengue virus molecular diagnostics KW - Enzyme-linked immunosorbent assay KW - Serotypes KW - Viruses KW - Algorithms KW - Reverse transcription KW - Infectious diseases KW - Dengue KW - Nonstructural proteins KW - Proteins KW - Polymerase chain reaction KW - Seroconversion KW - Viremia KW - Immunoassays KW - Immunoglobulin M KW - H 0500:General KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1827921892?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Performance+of+Dengue+Diagnostic+Tests+in+a+Single-Specimen+Diagnostic+Algorithm&rft.au=Hunsperger%2C+Elizabeth+A%3BMunoz-Jordan%2C+Jorge%3BBeltran%2C+Manuela%3BColon%2C+Candimar%3BCarrion%2C+Jessica%3BVazquez%2C+Jesus%3BAcosta%2C+Luz+Nereida%3BMedina-Izquierdo%2C+Juan+F%3BHoriuchi%2C+Kalanthe%3BBiggerstaff%2C+Brad+J%3BMargolis%2C+Harold+S&rft.aulast=Hunsperger&rft.aufirst=Elizabeth&rft.date=2016-09-15&rft.volume=214&rft.issue=6&rft.spage=836&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiw103 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-10-01 N1 - Last updated - 2016-10-26 N1 - SubjectsTermNotLitGenreText - Enzyme-linked immunosorbent assay; Serotypes; Dengue; Nonstructural proteins; Algorithms; Seroconversion; Polymerase chain reaction; Viremia; Immunoglobulin M; Reverse transcription; Infectious diseases; Viruses; Proteins; Immunoassays DO - http://dx.doi.org/10.1093/infdis/jiw103 ER - TY - JOUR T1 - Notification following new positive HIV test results AN - 1827926653; PQ0003637315 AB - Client notification of a new HIV diagnosis is critical for timely access to treatment and reduction in behaviours associated with HIV infection. It is also an important input in HIV transmission and disease progression models. We used national, Centers for Disease Control and Prevention-funded HIV testing events data collected through the National HIV Prevention Program Monitoring and Evaluation system to update estimates of the proportion of newly identified HIV-positives notified of their status. We compared estimates from 2008 to 2010 across test technologies, settings, and HIV risk groups. In 2010, notification following a positive rapid test was 99.6% compared with 99.3% in 2008. Notification following a positive conventional test was 81.5% in 2010 compared with 80.8% in 2008. To realise the full promise of early HIV diagnosis and treatment for the prevention of additional HIV cases, efforts to ensure prompt notification following a new HIV diagnosis will be crucial. JF - International Journal of STD & AIDS AU - Huang, Ya-Lin A AU - Hutchinson, Angela B AU - Hollis, NaTasha D AU - Sansom, Stephanie L Y1 - 2016/09// PY - 2016 DA - September 2016 SP - 868 EP - 872 PB - Sage Publications, Inc., 2455 Teller Road Thousand Oaks CA 91320 United States VL - 27 IS - 10 SN - 0956-4624, 0956-4624 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - HIV testing KW - receipt of test result KW - notification KW - rapid test KW - conventional test KW - Acquired immune deficiency syndrome KW - Data processing KW - Retroviridae KW - Disease control KW - Infection KW - Disease transmission KW - Models KW - Health risks KW - Prevention KW - Lentivirus KW - Risk groups KW - Sexually transmitted diseases KW - Technology KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1827926653?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+STD+%26+AIDS&rft.atitle=Notification+following+new+positive+HIV+test+results&rft.au=Huang%2C+Ya-Lin+A%3BHutchinson%2C+Angela+B%3BHollis%2C+NaTasha+D%3BSansom%2C+Stephanie+L&rft.aulast=Huang&rft.aufirst=Ya-Lin&rft.date=2016-09-01&rft.volume=27&rft.issue=10&rft.spage=868&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+STD+%26+AIDS&rft.issn=09564624&rft_id=info:doi/10.1177%2F0956462415598090 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-10-01 N1 - Number of references - 20 N1 - Last updated - 2016-11-09 N1 - SubjectsTermNotLitGenreText - Data processing; Disease control; Risk groups; Infection; Models; Disease transmission; Health risks; Acquired immune deficiency syndrome; Prevention; Sexually transmitted diseases; Technology; Lentivirus; Retroviridae DO - http://dx.doi.org/10.1177/0956462415598090 ER - TY - JOUR T1 - Tick-Borne Relapsing Fever Outbreak Among a High School Football Team at an Outdoor Education Camping Trip, Arizona, 2014 AN - 1827897379; PQ0003706336 AB - During August 2014, five high school students who had attended an outdoor education camp were hospitalized with a febrile illness, prompting further investigation. Ten total cases of tick-borne relapsing fever (TBRF) were identified-six cases confirmed by culture or visualization of spirochetes on blood smear and four probable cases with compatible symptoms (attack rate: 23%). All patients had slept in the campsite's only cabin. Before the camp, a professional pest control company had rodent proofed the cabin, but no acaricides had been applied. Cabin inspection after the camp found rodents and Ornithodoros ticks, the vector of TBRF. Blood samples from a chipmunk trapped near the cabin and from patients contained Borrelia hermsii with identical gene sequences (100% over 630 base pairs). Health departments in TBRF endemic areas should consider educating cabin owners and pest control companies to apply acaricides during or following rodent proofing, because ticks that lack rodents for a blood meal might feed on humans. JF - American Journal of Tropical Medicine and Hygiene AU - Jones, Jefferson M AU - Hranac, Carter R AU - Schumacher, Mare AU - Horn, Kim AU - Lee, Darlene M AU - Terriquez, Joel AU - Engelthaler, David M AU - Peoples, Marie AU - Corrigan, Jennifer AU - Replogle, Adam AU - Souders, Nina AU - Komatsu, Kenneth K AU - Nieto, Nathan C AD - Arizona Department of Health Services, Phoenix, Arizona, jjones10@cdc.gov Y1 - 2016/09// PY - 2016 DA - September 2016 SP - 546 EP - 550 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 95 IS - 3 SN - 0002-9637, 0002-9637 KW - Entomology Abstracts; Health & Safety Science Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Borrelia hermsii KW - Ixodidae KW - Camping KW - Cyclic AMP KW - Vectors KW - Pest control KW - Blood meals KW - Blood KW - Spirochetes KW - Schools KW - tick-borne diseases KW - USA, Arizona KW - Outbreaks KW - Acaricides KW - Inspection KW - Ornithodoros KW - Rodents KW - Adolescents KW - Hospitals KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - K 03400:Human Diseases KW - Z 05350:Medical, Veterinary, and Agricultural Entomology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1827897379?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Tick-Borne+Relapsing+Fever+Outbreak+Among+a+High+School+Football+Team+at+an+Outdoor+Education+Camping+Trip%2C+Arizona%2C+2014&rft.au=Jones%2C+Jefferson+M%3BHranac%2C+Carter+R%3BSchumacher%2C+Mare%3BHorn%2C+Kim%3BLee%2C+Darlene+M%3BTerriquez%2C+Joel%3BEngelthaler%2C+David+M%3BPeoples%2C+Marie%3BCorrigan%2C+Jennifer%3BReplogle%2C+Adam%3BSouders%2C+Nina%3BKomatsu%2C+Kenneth+K%3BNieto%2C+Nathan+C&rft.aulast=Jones&rft.aufirst=Jefferson&rft.date=2016-09-01&rft.volume=95&rft.issue=3&rft.spage=546&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.16-0054 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-10-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Spirochetes; Cyclic AMP; tick-borne diseases; Vectors; Pest control; Blood meals; Acaricides; Blood; Schools; Camping; Outbreaks; Inspection; Adolescents; Rodents; Hospitals; Borrelia hermsii; Ixodidae; Ornithodoros; USA, Arizona DO - http://dx.doi.org/10.4269/ajtmh.16-0054 ER - TY - JOUR T1 - Monitoring for Human Papillomavirus Vaccine Impact Among Gay, Bisexual, and Other Men Who Have Sex With Men-United States, 2012-2014 AN - 1819139349; PQ0003621078 AB - Background. Gay, bisexual, and other men who have sex with men (MSM) are at high risk for human papillomavirus (HPV) infection; vaccination is recommended for US males, including MSM through age 26 years. We assessed evidence of HPV among vaccine-eligible MSM and transgender women to monitor vaccine impact. Methods. During 2012-2014, MSM aged 18-26 years at select clinics completed a computer-assisted self-interview regarding sexual behavior, human immunodeficiency virus (HIV) status, and vaccinations. Self-collected anal swab and oral rinse specimens were tested for HPV DNA (37 types) by L1 consensus polymerase chain reaction; serum was tested for HPV antibodies (4 types) by a multiplexed virus-like particle-based immunoglobulin G direct enzyme-linked immunosorbent assay. Results. Among 922 vaccine-eligible participants, the mean age was 23 years, and the mean number of lifetime sex partners was 37. Among 834 without HIV infection, any anal HPV was detected in 69.4% and any oral HPV in 8.4%, yet only 8.5% had evidence of exposure to all quadrivalent vaccine types. In multivariate analysis, HPV prevalence varied significantly (P< .05) by HIV status, sexual orientation, and lifetime number of sex partners, but not by race/ethnicity. Discussions. Most young MSM lacked evidence of current or past infection with all vaccine-type HPV types, suggesting that they could benefit from vaccination. The impact of vaccination among MSM may be assessed by monitoring HPV prevalence, including in self-collected specimens. JF - Journal of Infectious Diseases AU - Meites, Elissa AU - Gorbach, Pamina M AU - Gratzer, Beau AU - Panicker, Gitika AU - Steinau, Martin AU - Collins, Tom AU - Parrish, Adam AU - Randel, Cody AU - McGrath, Mark AU - Carrasco, Steven AD - Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, emeites@cdc.gov Y1 - 2016/09/01/ PY - 2016 DA - 2016 Sep 01 SP - 689 EP - 696 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 214 IS - 5 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Immunology Abstracts; Health & Safety Science Abstracts KW - epidemiological monitoring KW - homosexuality, male KW - papillomavirus infections KW - papillomavirus vaccines KW - Risk assessment KW - Age KW - Males KW - Viruses KW - Particulates KW - Homosexuality KW - Infection KW - Sexual behavior KW - Lentivirus KW - Infectious diseases KW - Multivariate analysis KW - Bisexuality KW - Risk factors KW - Polymerase chain reaction KW - Races KW - Ethnic groups KW - Sex KW - Enzyme-linked immunosorbent assay KW - Vaccination KW - Human behavior KW - Human immunodeficiency virus KW - Bisexual KW - DNA KW - Immunoglobulin G KW - Vaccines KW - Immunoassays KW - Human papillomavirus KW - V 22360:AIDS and HIV KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1819139349?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Monitoring+for+Human+Papillomavirus+Vaccine+Impact+Among+Gay%2C+Bisexual%2C+and+Other+Men+Who+Have+Sex+With+Men-United+States%2C+2012-2014&rft.au=Meites%2C+Elissa%3BGorbach%2C+Pamina+M%3BGratzer%2C+Beau%3BPanicker%2C+Gitika%3BSteinau%2C+Martin%3BCollins%2C+Tom%3BParrish%2C+Adam%3BRandel%2C+Cody%3BMcGrath%2C+Mark%3BCarrasco%2C+Steven&rft.aulast=Meites&rft.aufirst=Elissa&rft.date=2016-09-01&rft.volume=214&rft.issue=5&rft.spage=689&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiw232 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-09-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Age; Enzyme-linked immunosorbent assay; Infection; Vaccination; Sexual behavior; Multivariate analysis; Risk factors; Bisexual; Immunoglobulin G; Polymerase chain reaction; Vaccines; Ethnic groups; Races; Sex; Risk assessment; Males; Viruses; Homosexuality; Particulates; Human behavior; Infectious diseases; Bisexuality; DNA; Immunoassays; Lentivirus; Human immunodeficiency virus; Human papillomavirus DO - http://dx.doi.org/10.1093/infdis/jiw232 ER - TY - JOUR T1 - Rotavirus Strain Trends During the Postlicensure Vaccine Era: United States, 2008-2013 AN - 1819137212; PQ0003621083 AB - Background. Group A rotaviruses (RVA) are a significant cause of pediatric gastroenteritis worldwide. The New Vaccine Surveillance Network (NVSN) has conducted active surveillance for RVA at pediatric hospitals and emergency departments at 3-7 geographically diverse sites in the United States since 2006. Methods. Over 6 consecutive years, from 2008 to 2013, 1523 samples from NVSN sites that were tested positive by a Rotaclone enzyme immunoassay were submitted to the Centers for Disease Control and Prevention for genotyping. Results. In the 2009, 2010, and 2011 seasons, genotype G3P[8] was the predominant genotype throughout the network, with a 46%-84% prevalence. In the 2012 season, G12P[8] replaced G3P[8] as the most common genotype, with a 70% prevalence, and this trend persisted in 2013 (68.0% prevalence). Vaccine (RotaTeq; Rotarix) strains were detected in 0.6%-3.4% of genotyped samples each season. Uncommon and unusual strains (eg, G8P[4], G3P[24], G2P[8], G3P[4], G3P[6], G24P[14], G4P[6], and G9P[4]) were detected sporadically over the study period. Year, study site, and race were found to be significant predictors of genotype. Conclusions. Continued active surveillance is needed to monitor RVA genotypes in the United States and to detect potential changes since vaccine licensure. JF - Journal of Infectious Diseases AU - Bowen, Michael D AU - Mijatovic-Rustempasic, Slavica AU - Esona, Mathew D AU - Teel, Elizabeth N AU - Gautam, Rashi AU - Sturgeon, Michele AU - Azimi, Parvin H AU - Baker, Carol J AU - Bernstein, David I AU - Boom, Julie A AD - Centers for Disease Control and Prevention, Atlanta, Georgia, mkb6@cdc.gov Y1 - 2016/09/01/ PY - 2016 DA - 2016 Sep 01 SP - 732 EP - 738 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 214 IS - 5 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Immunology Abstracts; Health & Safety Science Abstracts KW - rotavirus KW - genotype KW - prevalence KW - surveillance KW - vaccine KW - Rotavirus KW - Pediatrics KW - Genotyping KW - Disease control KW - Enzymes KW - Genotypes KW - Enzyme immunoassay KW - USA KW - Prevention KW - Infectious diseases KW - Vaccines KW - Gastroenteritis KW - Immunoassays KW - Races KW - Emergency medical services KW - Hospitals KW - V 22400:Human Diseases KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1819137212?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Rotavirus+Strain+Trends+During+the+Postlicensure+Vaccine+Era%3A+United+States%2C+2008-2013&rft.au=Bowen%2C+Michael+D%3BMijatovic-Rustempasic%2C+Slavica%3BEsona%2C+Mathew+D%3BTeel%2C+Elizabeth+N%3BGautam%2C+Rashi%3BSturgeon%2C+Michele%3BAzimi%2C+Parvin+H%3BBaker%2C+Carol+J%3BBernstein%2C+David+I%3BBoom%2C+Julie+A&rft.aulast=Bowen&rft.aufirst=Michael&rft.date=2016-09-01&rft.volume=214&rft.issue=5&rft.spage=732&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiw233 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-09-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Pediatrics; Genotyping; Disease control; Vaccines; Genotypes; Gastroenteritis; Races; Enzyme immunoassay; Hospitals; Prevention; Infectious diseases; Enzymes; Immunoassays; Emergency medical services; Rotavirus; USA DO - http://dx.doi.org/10.1093/infdis/jiw233 ER - TY - JOUR T1 - Epidemiology of a Novel Recombinant Middle East Respiratory Syndrome Coronavirus in Humans in Saudi Arabia AN - 1819136950; PQ0003621081 AB - Background. Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe respiratory illness in humans. Fundamental questions about circulating viruses and transmission routes remain. Methods. We assessed routinely collected epidemiologic data for MERS-CoV cases reported in Saudi Arabia during 1 January-30 June 2015 and conducted a more detailed investigation of cases reported during February 2015. Available respiratory specimens were obtained for sequencing. Results. During the study period, 216 MERS-CoV cases were reported. Full genome (n = 17) or spike gene sequences (n = 82) were obtained from 99 individuals. Most sequences (72 of 99 [73%]) formed a discrete, novel recombinant subclade (NRC-2015), which was detected in 6 regions and became predominant by June 2015. No clinical differences were noted between clades. Among 87 cases reported during February 2015, 13 had no recognized risks for secondary acquisition; 12 of these 13 also denied camel contact. Most viruses (8 of 9) from these 13 individuals belonged to NRC-2015. Discussions. Our findings document the spread and eventual predominance of NRC-2015 in humans in Saudi Arabia during the first half of 2015. Our identification of cases without recognized risk factors but with similar virus sequences indicates the need for better understanding of risk factors for MERS-CoV transmission. JF - Journal of Infectious Diseases AU - Assiri, Abdullah M AU - Midgley, Claire M AU - Abedi, Glen R AU - Saeed, Abdulaziz Bin AU - Almasri, Malak M AU - Lu, Xiaoyan AU - Al-Abdely, Hail M AU - Abdalla, Osman AU - Mohammed, Mutaz AU - Algarni, Homoud S AD - Ministry of Health, ydk5@cdc.gov Y1 - 2016/09/01/ PY - 2016 DA - 2016 Sep 01 SP - 712 EP - 721 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 214 IS - 5 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Immunology Abstracts; Health & Safety Science Abstracts KW - Middle East respiratory syndrome KW - MERS KW - coronavirus KW - MERS epidemiology KW - MERS transmission KW - MERS phylogeny KW - recombinant KW - Saudi Arabia KW - Risk assessment KW - Genomes KW - Data processing KW - Coronavirus KW - Viruses KW - Infectious diseases KW - Epidemiology KW - Risk factors KW - Middle East KW - H 1000:Occupational Safety and Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1819136950?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Epidemiology+of+a+Novel+Recombinant+Middle+East+Respiratory+Syndrome+Coronavirus+in+Humans+in+Saudi+Arabia&rft.au=Assiri%2C+Abdullah+M%3BMidgley%2C+Claire+M%3BAbedi%2C+Glen+R%3BSaeed%2C+Abdulaziz+Bin%3BAlmasri%2C+Malak+M%3BLu%2C+Xiaoyan%3BAl-Abdely%2C+Hail+M%3BAbdalla%2C+Osman%3BMohammed%2C+Mutaz%3BAlgarni%2C+Homoud+S&rft.aulast=Assiri&rft.aufirst=Abdullah&rft.date=2016-09-01&rft.volume=214&rft.issue=5&rft.spage=712&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiw236 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-09-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Genomes; Data processing; Epidemiology; Risk factors; Risk assessment; Infectious diseases; Viruses; Coronavirus; Saudi Arabia; Middle East DO - http://dx.doi.org/10.1093/infdis/jiw236 ER - TY - JOUR T1 - Fentanyl Law Enforcement Submissions and Increases in Synthetic Opioid-Involved Overdose Deaths - 27 States, 2013-2014. AN - 1814682213; 27560775 AB - In March and October 2015, the Drug Enforcement Administration (DEA) and CDC, respectively, issued nationwide alerts identifying illicitly manufactured fentanyl (IMF) as a threat to public health and safety (1,2). IMF is unlawfully produced fentanyl, obtained through illicit drug markets, includes fentanyl analogs, and is commonly mixed with or sold as heroin (1,3,4). Starting in 2013, the production and distribution of IMF increased to unprecedented levels, fueled by increases in the global supply, processing, and distribution of fentanyl and fentanyl-precursor chemicals by criminal organizations (3). Fentanyl is a synthetic opioid 50-100 times more potent than morphine (2).* Multiple states have reported increases in fentanyl-involved overdose (poisoning) deaths (fentanyl deaths) (2). This report examined the number of drug products obtained by law enforcement that tested positive for fentanyl (fentanyl submissions) and synthetic opioid-involved deaths other than methadone (synthetic opioid deaths), which include fentanyl deaths and deaths involving other synthetic opioids (e.g., tramadol). Fentanyl deaths are not reported separately in national data. Analyses also were conducted on data from 27 states(†) with consistent death certificate reporting of the drugs involved in overdoses. Nationally, the number of fentanyl submissions and synthetic opioid deaths increased by 426% and 79%, respectively, during 2013-2014; among the 27 analyzed states, fentanyl submission increases were strongly correlated with increases in synthetic opioid deaths. Changes in fentanyl submissions and synthetic opioid deaths were not correlated with changes in fentanyl prescribing rates, and increases in fentanyl submissions and synthetic opioid deaths were primarily concentrated in eight states (high-burden states). Reports from six of the eight high-burden states indicated that fentanyl-involved overdose deaths were primarily driving increases in synthetic opioid deaths. Increases in synthetic opioid deaths among high-burden states disproportionately involved persons aged 15-44 years and males, a pattern consistent with previously documented IMF-involved deaths (5). These findings, combined with the approximate doubling in fentanyl submissions during 2014-2015 (from 5,343 to 13,882) (6), underscore the urgent need for a collaborative public health and law enforcement response. JF - MMWR. Morbidity and mortality weekly report AU - Gladden, R Matthew AU - Martinez, Pedro AU - Seth, Puja AD - Division of Unintentional Injury Prevention, National Center for Injury Prevention and Control, CDC. Y1 - 2016/08/26/ PY - 2016 DA - 2016 Aug 26 SP - 837 EP - 843 VL - 65 IS - 33 KW - Street Drugs KW - 0 KW - Fentanyl KW - UF599785JZ KW - Index Medicus KW - Young Adult KW - Humans KW - Adult KW - Aged KW - Middle Aged KW - Adolescent KW - United States -- epidemiology KW - Male KW - Female KW - Opioid-Related Disorders -- mortality KW - Law Enforcement KW - Drug Overdose -- mortality KW - Street Drugs -- legislation & jurisprudence KW - Fentanyl -- poisoning UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1814682213?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=MMWR.+Morbidity+and+mortality+weekly+report&rft.atitle=Fentanyl+Law+Enforcement+Submissions+and+Increases+in+Synthetic+Opioid-Involved+Overdose+Deaths+-+27+States%2C+2013-2014.&rft.au=Gladden%2C+R+Matthew%3BMartinez%2C+Pedro%3BSeth%2C+Puja&rft.aulast=Gladden&rft.aufirst=R&rft.date=2016-08-26&rft.volume=65&rft.issue=33&rft.spage=837&rft.isbn=&rft.btitle=&rft.title=MMWR.+Morbidity+and+mortality+weekly+report&rft.issn=1545-861X&rft_id=info:doi/10.15585%2Fmmwr.mm6533a2 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2017-01-09 N1 - Date created - 2016-08-26 N1 - Date revised - 2017-01-14 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.15585/mmwr.mm6533a2 ER - TY - JOUR T1 - A case-control study evaluating the role of internet meet-up sites and mobile telephone applications in influencing a syphilis outbreak: Multnomah County, Oregon, USA 2014 AN - 1827932577; PQ0003499222 AB - ObjectivesEarly syphilis in Multnomah County, Oregon, USA, increased 16-fold during 2007-2013. Cases predominantly occurred among men who have sex with men (MSM); 55% were HIV coinfected. We conducted a case-control study to evaluate the association between meeting sex partners online and early syphilis.MethodsCases subjects (cases) were Multnomah County resident, English speaking, MSM, aged greater than or equal to 18 years with laboratory-confirmed early syphilis reported 1 January to 31 December 2013. We recruited two MSM controls subjects (controls) per case, frequency matched by HIV status and age. Participants completed self-administered questionnaires. We performed multivariable logistic regression.ResultsSeventy per cent (40/57) of cases and 42% (50/119) of controls met partners online (p<0.001). Cases more frequently met partners online (adjusted OR (aOR)=3.0; 95% CI 1.2 to 6.7), controlling for presumptive confounders. Cases reported more partners than controls (medians 5, 2; p<0.001). When including number of partners, aOR decreased to 1.4 (95% CI 0.5 to 3.9).ConclusionsEarly syphilis was associated with meeting partners online. We believe this association may be related to number of sex partners acting as an intermediate variable between use of online resources to meet sex partners and early syphilis. Online meet-up sites might represent areas for public health interventions targeting at-risk individuals. JF - Sexually Transmitted Infections AU - DeSilva, Malini AU - Hedberg, Katrina AU - Robinson, Byron AU - Toevs, Kim AU - Neblett-Fanfair, Robyn AU - Petrosky, Emiko AU - Hariri, Susan AU - Schafer, Sean AD - Epidemic Intelligence Service, Division of Scientific Education and Professional Development, Center for Surveillance, Epidemiology, and Laboratory Services, CDC, , Atlanta, Georgia, USA Y1 - 2016/08/17/ PY - 2016 DA - 2016 Aug 17 SP - 353 EP - 358 PB - British Medical Association, BMA House Square London WC1H 9JP United Kingdom VL - 92 IS - 5 SN - 1368-4973, 1368-4973 KW - Microbiology Abstracts B: Bacteriology KW - SYPHILIS KW - GAY MEN KW - PUBLIC HEALTH KW - Inventories KW - Lentivirus KW - Treponema pallidum KW - Cellular telephones KW - Syphilis KW - Internet KW - Sex KW - Public health KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1827932577?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Sexually+Transmitted+Infections&rft.atitle=A+case-control+study+evaluating+the+role+of+internet+meet-up+sites+and+mobile+telephone+applications+in+influencing+a+syphilis+outbreak%3A+Multnomah+County%2C+Oregon%2C+USA+2014&rft.au=DeSilva%2C+Malini%3BHedberg%2C+Katrina%3BRobinson%2C+Byron%3BToevs%2C+Kim%3BNeblett-Fanfair%2C+Robyn%3BPetrosky%2C+Emiko%3BHariri%2C+Susan%3BSchafer%2C+Sean&rft.aulast=DeSilva&rft.aufirst=Malini&rft.date=2016-08-17&rft.volume=92&rft.issue=5&rft.spage=353&rft.isbn=&rft.btitle=&rft.title=Sexually+Transmitted+Infections&rft.issn=13684973&rft_id=info:doi/10.1136%2Fsextrans-2015-052509 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-10-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Inventories; Cellular telephones; Syphilis; Internet; Public health; Sex; Lentivirus; Treponema pallidum DO - http://dx.doi.org/10.1136/sextrans-2015-052509 ER - TY - JOUR T1 - Varicella immunization requirements for US colleges: 2014-2015 academic year AN - 1811904197; PQ0003562904 AB - Objective: To obtain information on varicella prematriculation requirements in US colleges for undergraduate students during the 2014-2015 academic year. Participants: Health care professionals and member schools of the American College Health Association (ACHA). Methods: An electronic survey was sent to ACHA members regarding school characteristics and whether schools had policies in place requiring that students show proof of 2 doses of varicella vaccination for school attendance. Results: Only 27% (101/370) of schools had a varicella prematriculation requirement for undergraduate students. Only 68% of schools always enforced this requirement. Private schools, 4-year schools, northeastern schools, those with <5,000 students, and schools located in a state with a 2-dose varicella vaccine mandate were significantly more likely to have a varicella prematriculation requirement. Conclusions: A small proportion of US colleges have a varicella prematriculation requirement for varicella immunity. College vaccination requirements are an important tool for controlling varicella in these settings. JF - Journal of American College Health AU - Leung, Jessica AU - Marin, Mona AU - Leino, Victor AU - Even, Susan AU - Bialek, Stephanie R AD - National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA Y1 - 2016/08/17/ PY - 2016 DA - 2016 Aug 17 SP - 490 EP - 495 PB - Taylor & Francis Group Ltd., 2 Park Square Oxford OX14 4RN United Kingdom VL - 64 IS - 6 SN - 0744-8481, 0744-8481 KW - Physical Education Index KW - Schools KW - Private schools KW - College students KW - Objectives KW - Immune system KW - Higher education KW - College health KW - School health KW - Students KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1811904197?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+American+College+Health&rft.atitle=Varicella+immunization+requirements+for+US+colleges%3A+2014-2015+academic+year&rft.au=Leung%2C+Jessica%3BMarin%2C+Mona%3BLeino%2C+Victor%3BEven%2C+Susan%3BBialek%2C+Stephanie+R&rft.aulast=Leung&rft.aufirst=Jessica&rft.date=2016-08-17&rft.volume=64&rft.issue=6&rft.spage=490&rft.isbn=&rft.btitle=&rft.title=Journal+of+American+College+Health&rft.issn=07448481&rft_id=info:doi/10.1080%2F07448481.2016.1138481 LA - English DB - Physical Education Index N1 - Date revised - 2016-08-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Schools; College students; Private schools; Immune system; Objectives; Higher education; College health; School health; Students DO - http://dx.doi.org/10.1080/07448481.2016.1138481 ER - TY - JOUR T1 - The Evolution and Transmission of Epidemic GII.17 Noroviruses AN - 1811877107; PQ0003534620 AB - Background. In recent decades, the GII.4 norovirus genotype has predominated in epidemics worldwide and been associated with an increased rate of evolutionary change. In 2014, a novel GII.17 variant emerged and persisted, causing large outbreaks of gastroenteritis in China and sporadic infections globally. The origin, evolution, and transmission history of this new variant are largely unknown. Methods. We generated 103 full capsid and 8 whole-genome sequences of GII.17 strains collected between August 2013 and November 2015 in Guangdong, China. Phylogenetic analyses were performed by integrating our data with those for all publically available GII.17 sequences. Results. The novel emergent lineage GII.17_Kawasaki_2014 most likely originated from Africa around 2001 and evolved at a rate of 5.6 x 10 super(-3) substitutions/site/year. Within this lineage, a new variant containing several important amino acid changes emerged around August 2013 and caused extensive epidemics in 2014-2015. The phylodynamic and epidemic history of the GII.17_Kawasaki lineage shows similarities with the pattern observed for GII.4 norovirus evolution. Virus movements from Hong Kong to neighboring coastal cities were frequently observed. Conclusions. Our results provide new insights into GII.17 norovirus evolution and transmission and highlight the potential for a rare norovirus genotype to rapidly replace existing strains and cause local epidemics. JF - Journal of Infectious Diseases AU - Lu, Jing AU - Fang, Lin AU - Zheng, Huanying AU - Lao, Jiaqian AU - Yang, Fen AU - Sun, Limei AU - Xiao, Jianpeng AU - Lin, Jinyan AU - Song, Tie AU - Ni, Tao AD - Guangdong Provincial Center for Disease Control and Prevention Y1 - 2016/08/15/ PY - 2016 DA - 2016 Aug 15 SP - 556 EP - 564 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 214 IS - 4 SN - 0022-1899, 0022-1899 KW - Immunology Abstracts; Health & Safety Science Abstracts KW - norovirus KW - phylogenetic KW - phylogeographic KW - epidemic KW - virus transmission KW - Historical account KW - Amino acids KW - Viruses KW - Norovirus KW - Genotypes KW - Infection KW - Cities KW - Infectious diseases KW - Africa KW - China, People's Rep. KW - Outbreaks KW - Gastroenteritis KW - ISEW, China, People's Rep., Hong Kong KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1811877107?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=The+Evolution+and+Transmission+of+Epidemic+GII.17+Noroviruses&rft.au=Lu%2C+Jing%3BFang%2C+Lin%3BZheng%2C+Huanying%3BLao%2C+Jiaqian%3BYang%2C+Fen%3BSun%2C+Limei%3BXiao%2C+Jianpeng%3BLin%2C+Jinyan%3BSong%2C+Tie%3BNi%2C+Tao&rft.aulast=Lu&rft.aufirst=Jing&rft.date=2016-08-15&rft.volume=214&rft.issue=4&rft.spage=556&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiw208 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-08-01 N1 - Last updated - 2016-09-01 N1 - SubjectsTermNotLitGenreText - Cities; Historical account; Amino acids; Infectious diseases; Viruses; Outbreaks; Genotypes; Gastroenteritis; Infection; Norovirus; Africa; China, People's Rep.; ISEW, China, People's Rep., Hong Kong DO - http://dx.doi.org/10.1093/infdis/jiw208 ER - TY - JOUR T1 - Can you really swim? Validation of self and parental reports of swim skill with an inwater swim test among children attending community pools in Washington State AN - 1811885076; PQ0003499170 AB - BackgroundDrowning is the second leading cause of unintentional injury death among US children. Multiple studies describe decreased drowning risk among children possessing some swim skills. Current surveillance for this protective factor is self/proxy-reported swim skill rather than observed inwater performance; however, children's self-report or parents' proxy report of swim skill has not been validated. This is the first US study to evaluate whether children or parents can validly report a child's swim skill. It also explores which swim skill survey measure(s) correlate with children's inwater swim performance.MethodsFor this cross-sectional convenience-based sample, pilot study, child/parent dyads (N=482) were recruited at three outdoor public pools in Washington State. Agreement between measures of self-reports and parental-reports of children's swim skill was assessed via paired analyses, and validated by inwater swim test results.ResultsParticipants were representative of pool's patrons (ie, non-Hispanic White, highly educated, high income). There was agreement in child/parent dyads' reports of the following child swim skill measures: 'ever taken swim lessons', perceived 'good swim skills' and 'comfort in water over head'. Correlation analyses suggest that reported 'good swim skills' was the best survey measure to assess a child's swim skill-best if the parent was the informant (r=0.25-0.47). History of swim lessons was not significantly correlated with passing the swim test.ConclusionsReported 'good swim skills' was most correlated with observed swim skill. Reporting 'yes' to 'ever taken swim lessons' did not correlate with swim skill. While non-generalisable, findings can help inform future studies. JF - Injury Prevention AU - Mercado, Melissa C AU - Quan, Linda AU - Bennett, Elizabeth AU - Gilchrist, Julie AU - Levy, Benjamin A AU - Robinson, Candice L AU - Wendorf, Kristen AU - Gangan Fife, Maria Aurora AU - Stevens, Mark R AU - Lee, Robin AD - Division of Unintentional Injury Prevention, National Center for Injury Prevention and Control, CDC, , Atlanta, Georgia, USA Y1 - 2016/08/12/ PY - 2016 DA - 2016 Aug 12 SP - 253 EP - 260 PB - B M J Publishing Group, B.M.A. House London WC1H 9JR United Kingdom VL - 22 IS - 4 SN - 1353-8047, 1353-8047 KW - Physical Education Index; Health & Safety Science Abstracts KW - Risk assessment KW - Skill tests KW - Mortality KW - Historical account KW - Drowning KW - Injuries KW - Preventive health KW - Surveys KW - INE, USA, Washington KW - Children KW - Water KW - Income KW - Prevention KW - Risk factors KW - Analysis KW - Performance KW - Passing KW - H 11000:Diseases/Injuries/Trauma KW - PE 090:Sports Medicine & Exercise Sport Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1811885076?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Injury+Prevention&rft.atitle=Can+you+really+swim%3F+Validation+of+self+and+parental+reports+of+swim+skill+with+an+inwater+swim+test+among+children+attending+community+pools+in+Washington+State&rft.au=Mercado%2C+Melissa+C%3BQuan%2C+Linda%3BBennett%2C+Elizabeth%3BGilchrist%2C+Julie%3BLevy%2C+Benjamin+A%3BRobinson%2C+Candice+L%3BWendorf%2C+Kristen%3BGangan+Fife%2C+Maria+Aurora%3BStevens%2C+Mark+R%3BLee%2C+Robin&rft.aulast=Mercado&rft.aufirst=Melissa&rft.date=2016-08-12&rft.volume=22&rft.issue=4&rft.spage=253&rft.isbn=&rft.btitle=&rft.title=Injury+Prevention&rft.issn=13538047&rft_id=info:doi/10.1136%2Finjuryprev-2015-041680 LA - English DB - Physical Education Index; ProQuest Environmental Science Collection N1 - Date revised - 2016-08-01 N1 - Last updated - 2017-01-18 N1 - SubjectsTermNotLitGenreText - Skill tests; Injuries; Preventive health; Analysis; Surveys; Performance; Children; Passing; Water; Risk assessment; Historical account; Mortality; Prevention; Drowning; Risk factors; Income; INE, USA, Washington DO - http://dx.doi.org/10.1136/injuryprev-2015-041680 ER - TY - JOUR T1 - Pathology of congenital Zika syndrome in Brazil: a case series AN - 1827928282; PQ0003629552 AB - Background Zika virus is an arthropod-borne virus that is a member of the family Flaviviridae transmitted mainly by mosquitoes of the genus Aedes. Although usually asymptomatic, infection can result in a mild and self-limiting illness characterised by fever, rash, arthralgia, and conjunctivitis. An increase in the number of children born with microcephaly was noted in 2015 in regions of Brazil with high transmission of Zika virus. More recently, evidence has been accumulating supporting a link between Zika virus and microcephaly. Here, we describe findings from three fatal cases and two spontaneous abortions associated with Zika virus infection. Methods In this case series, formalin-fixed paraffin-embedded tissue samples from five cases, including two newborn babies with microcephaly and severe arthrogryposis who died shortly after birth, one 2-month-old baby, and two placentas from spontaneous abortions, from Brazil were submitted to the Infectious Diseases Pathology Branch at the US Centers for Disease Control and Prevention (Atlanta, GA, USA) between December, 2015, and March, 2016. Specimens were assessed by histopathological examination, immunohistochemical assays using a mouse anti-Zika virus antibody, and RT-PCR assays targeting the NS5 and envelope genes. Amplicons of RT-PCR positive cases were sequenced for characterisation of strains. Findings Viral antigens were localised to glial cells and neurons and associated with microcalcifications in all three fatal cases with microcephaly. Antigens were also seen in chorionic villi of one of the first trimester placentas. Tissues from all five cases were positive for Zika virus RNA by RT-PCR, and sequence analyses showed highest identities with Zika virus strains isolated from Brazil during 2015. Interpretation These findings provide strong evidence of a link between Zika virus infection and different congenital central nervous system malformations, including microcephaly as well as arthrogryposis and spontaneous abortions. Funding None. JF - Lancet AU - Martines, Roosecelis Brasil AU - Bhatnagar, Julu AU - de Oliveira Ramos, Ana Maria AU - Davi, Helaine Pompeia Freire AU - Iglezias, Silvia D'Andretta AU - Kanamura, Cristina Takami AU - Keating, M Kelly AU - Hale, Gillian AU - Silva-Flannery, Luciana AU - Muehlenbachs, Atis AU - Ritter, Jana AU - Gary, Joy AU - Rollin, Dominique AU - Goldsmith, Cynthia S AU - Reagan-Steiner, Sarah AU - Ermias, Yokabed AU - Suzuki, Tadaki AU - Luz, Kleber G AU - de Oliveira, Wanderson Kleber AU - Lanciotti, Robert AU - Lambert, Amy AU - Shieh, Wun-Ju AU - Zaki, Sherif R AD - Infectious Diseases Pathology Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), Atlanta, GA, USA Y1 - 2016/08// PY - 2016 DA - August 2016 SP - 898 EP - 904 PB - Elsevier B.V., Radarweg 29 Amsterdam 1043 NX Netherlands VL - 388 IS - 10047 SN - 0140-6736, 0140-6736 KW - Toxicology Abstracts KW - Central nervous system KW - Aedes KW - Zika virus KW - Nucleotide sequence KW - Abortion KW - Disease control KW - RNA viruses KW - Conjunctivitis KW - Children KW - Flaviviridae KW - Arthrogryposis KW - Fever KW - Exanthema KW - Antibodies KW - Envelopes KW - Infectious diseases KW - RNA KW - Neurotransmission KW - Microencephaly KW - Placenta KW - Congenital defects KW - Polymerase chain reaction KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1827928282?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Lancet&rft.atitle=Pathology+of+congenital+Zika+syndrome+in+Brazil%3A+a+case+series&rft.au=Martines%2C+Roosecelis+Brasil%3BBhatnagar%2C+Julu%3Bde+Oliveira+Ramos%2C+Ana+Maria%3BDavi%2C+Helaine+Pompeia+Freire%3BIglezias%2C+Silvia+D%27Andretta%3BKanamura%2C+Cristina+Takami%3BKeating%2C+M+Kelly%3BHale%2C+Gillian%3BSilva-Flannery%2C+Luciana%3BMuehlenbachs%2C+Atis%3BRitter%2C+Jana%3BGary%2C+Joy%3BRollin%2C+Dominique%3BGoldsmith%2C+Cynthia+S%3BReagan-Steiner%2C+Sarah%3BErmias%2C+Yokabed%3BSuzuki%2C+Tadaki%3BLuz%2C+Kleber+G%3Bde+Oliveira%2C+Wanderson+Kleber%3BLanciotti%2C+Robert%3BLambert%2C+Amy%3BShieh%2C+Wun-Ju%3BZaki%2C+Sherif+R&rft.aulast=Martines&rft.aufirst=Roosecelis&rft.date=2016-08-01&rft.volume=388&rft.issue=10047&rft.spage=898&rft.isbn=&rft.btitle=&rft.title=Lancet&rft.issn=01406736&rft_id=info:doi/10.1016%2FS0140-6736%2816%2930883-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-10-01 N1 - Number of references - 29 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Central nervous system; Abortion; Nucleotide sequence; Disease control; RNA viruses; Conjunctivitis; Children; Arthrogryposis; Fever; Exanthema; Antibodies; Envelopes; Neurotransmission; RNA; Infectious diseases; Microencephaly; Placenta; Polymerase chain reaction; Congenital defects; Aedes; Zika virus; Flaviviridae DO - http://dx.doi.org/10.1016/S0140-6736(16)30883-2 ER - TY - JOUR T1 - Evaluation of the Impact of the Revised National Institute for Occupational Safety and Health Lifting Equation AN - 1827890315; PQ0003686890 AB - Objective: The objective of this article is to evaluate the impact of the Revised National Institute for Occupational Safety and Health Lifting Equation (RNLE). Background: The RNLE has been used extensively as a risk assessment method for prevention of low back pain (LBP). However, the impact of the RNLE has not been documented. Methods: A systematic review of the literature on the RNLE was conducted. The review consisted of three parts: characterization of the RNLE publications, assessment of the impact of the RNLE, and evaluation of the influences of the RNLE on ergonomic standards. The literature for assessing the impact was categorized into four research areas: methodology, laboratory, field, and risk assessment studies using the Lifting Index (LI) or Composite LI (CLI), both of which are the products of the RNLE. Results: The impact of the RNLE has been both widespread and influential. We found 24 studies that examined the criteria used to define lifting capacity used by the RNLE, 28 studies that compared risk assessment methods for identifying LBP, 23 studies that found the RNLE useful in identifying the risk of LBP with different work populations, and 13 studies on the relationship between LI/CLI and LBP outcomes. We also found evidence on the adoption of the RNLE as an ergonomic standard for use by various local, state, and international entities. Conclusion: The review found 13 studies that link LI/CLI to adverse LBP outcomes. These studies showed a positive relationship between LI/CLI metrics and the severity of LBP outcomes. JF - Human Factors AU - Lu, Ming-Lun AU - Putz-Anderson, Vern AU - Garg, Arun AU - Davis, Kermit G AD - Taft Laboratories, Cincinnati, Ohio, mlu@cdc.gov Y1 - 2016/08// PY - 2016 DA - August 2016 SP - 667 EP - 682 PB - Sage Publications, Inc., 2455 Teller Road Thousand Oaks CA 91320 USA VL - 58 IS - 5 SN - 0018-7208, 0018-7208 KW - Health & Safety Science Abstracts KW - Revised NIOSH Lifting Equation KW - lifting index KW - manual lifting KW - low back pain KW - impact KW - Risk assessment KW - Prevention KW - Risk factors KW - Occupational safety KW - Human factors KW - Low back pain KW - Ergonomics KW - Working conditions KW - International standardization KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1827890315?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Human+Factors&rft.atitle=Evaluation+of+the+Impact+of+the+Revised+National+Institute+for+Occupational+Safety+and+Health+Lifting+Equation&rft.au=Lu%2C+Ming-Lun%3BPutz-Anderson%2C+Vern%3BGarg%2C+Arun%3BDavis%2C+Kermit+G&rft.aulast=Lu&rft.aufirst=Ming-Lun&rft.date=2016-08-01&rft.volume=58&rft.issue=5&rft.spage=667&rft.isbn=&rft.btitle=&rft.title=Human+Factors&rft.issn=00187208&rft_id=info:doi/10.1177%2F0018720815623894 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-10-01 N1 - Number of references - 109 N1 - Last updated - 2016-10-26 N1 - SubjectsTermNotLitGenreText - Risk assessment; Prevention; Risk factors; Occupational safety; Low back pain; Human factors; Working conditions; Ergonomics; International standardization DO - http://dx.doi.org/10.1177/0018720815623894 ER - TY - JOUR T1 - Rift Valley fever virus: Unanswered questions AN - 1815701943; PQ0003565030 AB - This mosquito-borne pathogen of humans and animals respects no international or geographic boundaries. It is currently found in parts of Africa and the Arabian Peninsula where periodic outbreaks of severe and fatal disease occur, and threatens to spread into other geographic regions. In recent years, modern molecular techniques have led to many breakthroughs deepening our understanding of the mechanisms of RVFV virulence, phylogenetics, and the creation of several next-generation vaccine candidates. Despite tremendous progress in these areas, other challenges remain in RVF disease pathogenesis, the virus life-cycle, and outbreak response preparedness that deserve our attention. Here we discuss and highlight ten key knowledge gaps and challenges in RVFV research. Answers to these key questions may lead to the development of new effective therapeutics and enhanced control strategies for this serious human and veterinary health threat. JF - Antiviral Research AU - Bird, Brian H AU - McElroy, Anita K AD - Viral Special Pathogens Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA Y1 - 2016/08// PY - 2016 DA - August 2016 SP - 274 EP - 280 PB - Elsevier B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 132 SN - 0166-3542, 0166-3542 KW - Virology & AIDS Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Rift Valley fever virus KW - Zoonoses KW - Epizootic KW - Reservoir KW - Mosquito KW - Arbovirus KW - Virulence KW - Phylogeny KW - Boundaries KW - Rift Valley fever KW - Vaccines KW - Pathogens KW - A 01340:Antibiotics & Antimicrobials KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1815701943?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antiviral+Research&rft.atitle=Rift+Valley+fever+virus%3A+Unanswered+questions&rft.au=Bird%2C+Brian+H%3BMcElroy%2C+Anita+K&rft.aulast=Bird&rft.aufirst=Brian&rft.date=2016-08-01&rft.volume=132&rft.issue=&rft.spage=274&rft.isbn=&rft.btitle=&rft.title=Antiviral+Research&rft.issn=01663542&rft_id=info:doi/10.1016%2Fj.antiviral.2016.07.005 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-08-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Phylogeny; Virulence; Boundaries; Rift Valley fever; Pathogens; Vaccines; Rift Valley fever virus DO - http://dx.doi.org/10.1016/j.antiviral.2016.07.005 ER - TY - JOUR T1 - Prevalence and Diversity of Bartonella Species in Rodents from Georgia (Caucasus) AN - 1815695313; PQ0003607539 AB - Bartonella infections are widespread and highly prevalent in rodents. Several rodent-associated Bartonella species have been related to human diseases. Recently, Bartonella species was reported as the etiology of a human case in the country of Georgia (Caucasus). However, information on Bartonella in rodents in Georgia is absent. Rodent hearts were collected from Georgia to investigate the presence and diversity of Bartonella species. Bartonella bacteria were cultured from 37.2% (16/43) of rodents examined, while Bartonella DNA was detected in 41.2% (28/68) of rodents by polymerase chain reaction targeting citrate synthase (gltA) gene. Sequences of gltA showed that rodents in this region harbored multiple Bartonella strains, including Bartonella elizabethae, Bartonella tribocorum, Bartonella grahamii, and an unknown genogroup. The first three Bartonella species, known to be rat-associated and human cases linked, were commonly observed in wood mice (Apodemus[Sylvaemus] uralensis) (5/8 positive with B. elizabethae and B. tribocorum) and social voles (Microtus socialis) (4/6 positive with B. grahamii and B. elizabethae) in this study. The frequent distribution of these Bartonella species suggests that they may contribute to unidentified clinical infections. The unknown genogroup was observed in 24 Bartonella isolates and/or DNA extracts from heart tissues, all of which were obtained from Libyan jirds(Meriones libycus). Further characterization of the bacterial cultures based on sequence analysis of four additional genes (ftsZ, nuoG, rpoB, and ssrA) supported that the jird-associated Bartonella strains comprise a distinct monophyletic clade. The impact of this bacterium on wildlife and human health needs to be determined. JF - American Journal of Tropical Medicine and Hygiene AU - Malania, Lile AU - Bai, Ying AU - Osikowicz, Lynn M AU - Tsertsvadze, Nikoloz AU - Katsitadze, Guram AU - Imnadze, Paata AU - Kosoy, Michael AD - General Bacteriology Laboratory, National Center for Disease Control and Public Health, Tbilisi, Republic of Georgia, bby5@cdc.gov Y1 - 2016/08// PY - 2016 DA - August 2016 SP - 466 EP - 471 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 95 IS - 2 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Heart KW - Bacteria KW - Etiology KW - Bartonella elizabethae KW - Bartonella KW - Wildlife KW - Bartonella grahamii KW - Wood KW - Mice KW - Infection KW - Microtus socialis KW - ASW, USA, Georgia KW - gltA gene KW - Species diversity KW - DNA KW - Polymerase chain reaction KW - Rodents KW - RpoB protein KW - Citric acid KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - K 03310:Genetics & Taxonomy KW - J 02450:Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1815695313?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Prevalence+and+Diversity+of+Bartonella+Species+in+Rodents+from+Georgia+%28Caucasus%29&rft.au=Malania%2C+Lile%3BBai%2C+Ying%3BOsikowicz%2C+Lynn+M%3BTsertsvadze%2C+Nikoloz%3BKatsitadze%2C+Guram%3BImnadze%2C+Paata%3BKosoy%2C+Michael&rft.aulast=Malania&rft.aufirst=Lile&rft.date=2016-08-01&rft.volume=95&rft.issue=2&rft.spage=466&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.16-0041 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-08-01 N1 - Last updated - 2016-10-26 N1 - SubjectsTermNotLitGenreText - Heart; Etiology; gltA gene; Wildlife; Polymerase chain reaction; Infection; RpoB protein; Citric acid; Bacteria; Species diversity; DNA; Wood; Mice; Rodents; Microtus socialis; Bartonella elizabethae; Bartonella; Bartonella grahamii; ASW, USA, Georgia DO - http://dx.doi.org/10.4269/ajtmh.16-0041 ER - TY - JOUR T1 - Prevalence of Hepatitis B Virus Infection in Kenya, 2007 AN - 1815691170; PQ0003607517 AB - Current estimates put the prevalence of hepatitis B virus (HBV) infection in Kenya at 5-8%. We determined the HBV infection prevalence in the human immunodeficiency virus (HIV)-negative Kenyan adult and adolescent population based on samples collected from a national survey. We analyzed data from HIV-negative participants in the 2007 Kenya AIDS Indicator Survey to estimate the HBV infection prevalence. We defined past or present HBV infection as presence of total hepatitis B core antibody (HBcAb), and chronic HBV infection (CHBI) as presence of both total HBcAb and hepatitis B surface antigen (HBsAg). We calculated crude and adjusted odds of HBV infection by demographic characteristics and risk factors using logistic regression analyses. Of 1,091 participants aged 15-64 years, approximately 31.5% (95% confidence interval [CI] = 28.0-35.3%) had exposure to HBV, corresponding to approximately 6.1 million (CI = 5.4-6.8 million) with past or present HBV infection. The estimated prevalence of CHBI was 2.1% (95% CI = 1.4-3.1%), corresponding to approximately 398,000 (CI = 261,000-602,000) with CHBI. CHBI is a major public health problem in Kenya, affecting approximately 400,000 persons. Knowing the HBV infection prevalence at baseline is important for planning and public health policy decision making and for monitoring the impact of viral hepatitis prevention programs. JF - American Journal of Tropical Medicine and Hygiene AU - Ly, Kathleen N AU - Kim, Andrea A AU - Umuro, Mamo AU - Drobenuic, Jan AU - Williamson, John M AU - Montgomery, Joel M AU - Fields, Barry S AU - Teshale, Eyasu H AD - Division of Viral Hepatitis, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, kathleen.ly@cdc.gov Y1 - 2016/08// PY - 2016 DA - August 2016 SP - 348 EP - 353 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 95 IS - 2 SN - 0002-9637, 0002-9637 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Acquired immune deficiency syndrome KW - Viruses KW - Hepatitis B surface antigen KW - Infection KW - Public health KW - Demography KW - Kenya KW - Lentivirus KW - Risk factors KW - Regression analysis KW - Adolescents KW - Data processing KW - Hepatitis B virus KW - Adolescence KW - Hepatitis KW - Decision making KW - Prevention KW - Antibodies KW - Human immunodeficiency virus KW - Chronic infection KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - V 22360:AIDS and HIV KW - K 03400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1815691170?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Prevalence+of+Hepatitis+B+Virus+Infection+in+Kenya%2C+2007&rft.au=Ly%2C+Kathleen+N%3BKim%2C+Andrea+A%3BUmuro%2C+Mamo%3BDrobenuic%2C+Jan%3BWilliamson%2C+John+M%3BMontgomery%2C+Joel+M%3BFields%2C+Barry+S%3BTeshale%2C+Eyasu+H&rft.aulast=Ly&rft.aufirst=Kathleen&rft.date=2016-08-01&rft.volume=95&rft.issue=2&rft.spage=348&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.16-0059 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-08-01 N1 - Last updated - 2016-10-26 N1 - SubjectsTermNotLitGenreText - Demography; Decision making; Antibodies; Acquired immune deficiency syndrome; Data processing; Risk factors; Adolescence; Chronic infection; Regression analysis; Hepatitis B surface antigen; Public health; Hepatitis; Prevention; Viruses; Infection; Adolescents; Lentivirus; Hepatitis B virus; Human immunodeficiency virus; Kenya DO - http://dx.doi.org/10.4269/ajtmh.16-0059 ER - TY - JOUR T1 - Features in Grocery Stores that Motivate Shoppers to Buy Healthier Foods, ConsumerStyles 2014 AN - 1808733010; PQ0003390576 AB - We examined nine features in grocery stores shoppers reported motivated them to purchase more healthful foods in the past month. Features were compiled from common supermarket practices for each of the 4 Ps of marketing: pricing, placement, promotion, and product. We examined percentages of the features overall and by shopping frequency using Chi square tests from a 2014 cross sectional web-based health attitudes and behaviors survey, ConsumerStyles. The survey was fielded from June to July in 2014. Participants were part of a market research consumer panel that were randomly recruited by probability-based sampling using address-based sampling methods to achieve a sample representative of the U.S. population. Data from 4242 adults ages 18 and older were analyzed. About 44 % of respondents indicated at least one feature motivated them to purchase more healthful foods. Top choices included in-store coupons or specials (20.1 %), availability of convenient, ready-to-eat more healthful foods (18.8 %), product labels or advertising on packages (15.2 %), and labels or signs on shelves that highlighted more healthful options (14.6 %). Frequent shoppers reported being motivated to purchase more healthful foods by in-store tastings/recipe demonstrations and coupons/specials more often than infrequent shoppers. Enhancing the visibility and appeal of more healthful food items in grocery stores may help improve dietary choices in some populations but additional research is needed to identify the most effective strategies for interventions. JF - Journal of Community Health AU - Moore, Latetia V AU - Pinard, Courtney A AU - Yaroch, Amy L AD - Division of Nutrition, Physical Activity and Obesity, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Hwy NE MS F-77, Atlanta, GA, 30341, USA, lvmoore@cdc.gov Y1 - 2016/08// PY - 2016 DA - August 2016 SP - 812 EP - 817 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 41 IS - 4 SN - 0094-5145, 0094-5145 KW - Health & Safety Science Abstracts KW - Diets KW - Attitudes KW - Pricing KW - Age KW - Marketing KW - Intervention KW - Visibility KW - Advertising KW - Sampling methods KW - H 9000:Consumer and Recreation Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808733010?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Community+Health&rft.atitle=Features+in+Grocery+Stores+that+Motivate+Shoppers+to+Buy+Healthier+Foods%2C+ConsumerStyles+2014&rft.au=Moore%2C+Latetia+V%3BPinard%2C+Courtney+A%3BYaroch%2C+Amy+L&rft.aulast=Moore&rft.aufirst=Latetia&rft.date=2016-08-01&rft.volume=41&rft.issue=4&rft.spage=812&rft.isbn=&rft.btitle=&rft.title=Journal+of+Community+Health&rft.issn=00945145&rft_id=info:doi/10.1007%2Fs10900-016-0158-x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Number of references - 23 N1 - Last updated - 2016-09-01 N1 - SubjectsTermNotLitGenreText - Diets; Age; Pricing; Attitudes; Marketing; Intervention; Visibility; Advertising; Sampling methods DO - http://dx.doi.org/10.1007/s10900-016-0158-x ER - TY - JOUR T1 - Will Culling White-Tailed Deer Prevent Lyme Disease? AN - 1808670749; PQ0003393991 AB - White-tailed deer play an important role in the ecology of Lyme disease. In the United States, where the incidence and geographic range of Lyme disease continue to increase, reduction of white-tailed deer populations has been proposed as a means of preventing human illness. The effectiveness of this politically sensitive prevention method is poorly understood. We summarize and evaluate available evidence regarding the effect of deer reduction on vector tick abundance and human disease incidence. Elimination of deer from islands and other isolated settings can have a substantial impact on the reproduction of blacklegged ticks, while reduction short of complete elimination has yielded mixed results. To date, most studies have been conducted in ecologic situations that are not representative to the vast majority of areas with high human Lyme disease risk. Robust evidence linking deer control to reduced human Lyme disease risk is lacking. Currently, there is insufficient evidence to recommend deer population reduction as a Lyme disease prevention measure, except in specific ecologic circumstances. JF - Zoonoses and Public Health AU - Kugeler, K J AU - Jordan, R A AU - Schulze, T L AU - Griffith, K S AU - Mead, P S AD - National Center for Emerging and Zoonotic Infectious Diseases, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, CO, USA. Y1 - 2016/08// PY - 2016 DA - August 2016 SP - 337 EP - 345 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 63 IS - 5 SN - 1863-1959, 1863-1959 KW - Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Human diseases KW - Abundance KW - Disease control KW - Hosts KW - Public health KW - Disease transmission KW - Ecology KW - Islands KW - Deer KW - Lyme disease KW - Ixodidae KW - Vectors KW - Methodology KW - USA KW - Prevention KW - Zoonoses KW - Culling KW - Reviews KW - Borrelia KW - Reproduction KW - J 02410:Animal Diseases KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - Q1 08485:Species interactions: pests and control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808670749?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Zoonoses+and+Public+Health&rft.atitle=Will+Culling+White-Tailed+Deer+Prevent+Lyme+Disease%3F&rft.au=Kugeler%2C+K+J%3BJordan%2C+R+A%3BSchulze%2C+T+L%3BGriffith%2C+K+S%3BMead%2C+P+S&rft.aulast=Kugeler&rft.aufirst=K&rft.date=2016-08-01&rft.volume=63&rft.issue=5&rft.spage=337&rft.isbn=&rft.btitle=&rft.title=Zoonoses+and+Public+Health&rft.issn=18631959&rft_id=info:doi/10.1111%2Fzph.12245 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Ecology; Human diseases; Culling; Disease control; Vectors; Hosts; Methodology; Disease transmission; Public health; Zoonoses; Islands; Reviews; Abundance; Reproduction; Lyme disease; Prevention; Deer; Ixodidae; Borrelia; USA DO - http://dx.doi.org/10.1111/zph.12245 ER - TY - JOUR T1 - Suicide among people with epilepsy: A population-based analysis of data from the U.S. National Violent Death Reporting System, 17 states, 2003-2011. AN - 1808387736; 27372961 AB - This study analyzed suicide data in the general population from the U.S. National Violent Death Reporting System (NVDRS) to investigate suicide burden among those with epilepsy and risk factors associated with suicide and to suggest measures to prevent suicide among people with epilepsy. The NVDRS is a multiple-state, population-based, active surveillance system that collects information on violent deaths including suicide. Among people 10years old and older, we identified 972 suicide cases with epilepsy and 81,529 suicide cases without epilepsy in 17 states from 2003 through 2011. We estimated their suicide rates, evaluated suicide risk among people with epilepsy, and investigated suicide risk factors specific to epilepsy by comparing those with and without epilepsy. In 16 of the 17 states providing continual data from 2005 through 2011, we also compared suicide trends in people with epilepsy (n=833) and without epilepsy (n=68,662). From 2003 through 2011, the estimated annual suicide mortality rate among people with epilepsy was 16.89/100,000 per persons, 22% higher than that in the general population. Compared with those without epilepsy, those with epilepsy were more likely to have died from suicide in houses, apartments, or residential institutions (81% vs. 76%, respectively) and were twice as likely to poison themselves (38% vs. 17%) (P<0.01). More of those with epilepsy aged 40-49 died from suicide than comparably aged persons without epilepsy (29% vs. 22%) (P<0.01). The proportion of suicides among those with epilepsy increased steadily from 2005 through 2010, peaking significantly in 2010 before falling. For the first time, the suicide rate among people with epilepsy in a large U.S. general population was estimated, and the suicide risk exceeded that in the general population. Suicide prevention efforts should target people with epilepsy 40-49years old. Additional preventive efforts include reducing the availability or exposure to poisons, especially at home, and supporting other evidence-based programs to reduce mental illness comorbidity associated with suicide. Published by Elsevier Inc. JF - Epilepsy & behavior : E&B AU - Tian, Niu AU - Cui, Wanjun AU - Zack, Matthew AU - Kobau, Rosemarie AU - Fowler, Katherine A AU - Hesdorffer, Dale C AD - Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, United States. Electronic address: vii9@cdc.gov. ; Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, United States. ; Division of Violence Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA 30341, United States. ; GH Sergievsky Center and Mailman School of Public Health, Columbia University, New York, NY 10032, United States. Y1 - 2016/08// PY - 2016 DA - August 2016 SP - 210 EP - 217 VL - 61 KW - Index Medicus KW - Epidemiology KW - Epilepsy KW - Suicide KW - Population KW - Rate UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808387736?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epilepsy+%26+behavior+%3A+E%26B&rft.atitle=Suicide+among+people+with+epilepsy%3A+A+population-based+analysis+of+data+from+the+U.S.+National+Violent+Death+Reporting+System%2C+17+states%2C+2003-2011.&rft.au=Tian%2C+Niu%3BCui%2C+Wanjun%3BZack%2C+Matthew%3BKobau%2C+Rosemarie%3BFowler%2C+Katherine+A%3BHesdorffer%2C+Dale+C&rft.aulast=Tian&rft.aufirst=Niu&rft.date=2016-08-01&rft.volume=61&rft.issue=&rft.spage=210&rft.isbn=&rft.btitle=&rft.title=Epilepsy+%26+behavior+%3A+E%26B&rft.issn=1525-5069&rft_id=info:doi/10.1016%2Fj.yebeh.2016.05.028 LA - English DB - ProQuest Environmental Science Collection N1 - Date created - 2016-08-01 N1 - Date revised - 2017-01-14 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1016/j.yebeh.2016.05.028 ER - TY - JOUR T1 - Associations of Teen Dating Violence Victimization With School Violence and Bullying Among US High School Students AN - 1801372475 AB - BACKGROUND Teen dating violence (TDV) negatively impacts health, mental and physical well-being, and school performance. METHODS Data from a nationally representative sample of high school students participating in the Centers for Disease Control and Prevention (CDC)'s 2013 Youth Risk Behavior Survey (YRBS) are used to demonstrate associations of physical and sexual TDV with school violence-related experiences and behaviors, including bullying victimization. Bivariate and adjusted sex-stratified regressions assessed relationships between TDV and school violence-related experiences and behaviors. RESULTS Compared to students not reporting TDV, those experiencing both physical and sexual TDV were more likely to report carrying a weapon at school, missing school because they felt unsafe, being threatened or injured with a weapon on school property, having a physical fight at school, and being bullied on school property. CONCLUSIONS School-based prevention efforts should target multiple forms of violence. JF - The Journal of School Health AU - Vivolo-Kantor, Alana M AU - Olsen, Emily O'Malley AU - Bacon, Sarah AD - Centers for Disease Control and Prevention, National Center for Injury Prevention and Control, Division of Violence Prevention, Atlanta, GA ; Centers for Disease Control and Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Division of Adolescent and School Health, Atlanta, GA ; Centers for Disease Control and Prevention, National Center for Injury Prevention and Control, Division of Unintentional Injury Prevention, Atlanta, GA Y1 - 2016/08// PY - 2016 DA - Aug 2016 SP - 620 EP - 627 CY - Kent PB - Wiley Subscription Services, Inc. VL - 86 IS - 8 SN - 0022-4391 KW - Physical Fitness And Hygiene KW - Behavior KW - Teenagers KW - Violence KW - Bullying KW - School violence KW - Victimization KW - Academic achievement KW - Mental health KW - Wellbeing KW - Unsafe KW - Risk behaviour KW - Health status KW - Gender violence KW - Preventive programmes KW - School based KW - Dating KW - Property KW - United States--US UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1801372475?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+School+Health&rft.atitle=Associations+of+Teen+Dating+Violence+Victimization+With+School+Violence+and+Bullying+Among+US+High+School+Students&rft.au=Vivolo-Kantor%2C+Alana+M%3BOlsen%2C+Emily+O%27Malley%3BBacon%2C+Sarah&rft.aulast=Vivolo-Kantor&rft.aufirst=Alana&rft.date=2016-08-01&rft.volume=86&rft.issue=8&rft.spage=620&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+School+Health&rft.issn=00224391&rft_id=info:doi/10.1111%2Fjosh.12412 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Name - Centers for Disease Control & Prevention--CDC N1 - Copyright - © 2016, American School Health Association N1 - Last updated - 2016-08-16 N1 - SubjectsTermNotLitGenreText - United States--US DO - http://dx.doi.org/10.1111/josh.12412 ER - TY - JOUR T1 - Parenting Among Adolescents and Young Adults with Human Immunodeficiency Virus Infection in the United States: Challenges, Unmet Needs, and Opportunities AN - 1859486690; PQ0003988395 AB - Given the realistic expectations of HIV-infected adolescents and young adults (AYA) to have children and start families, steps must be taken to ensure that youth are prepared to deal with the challenges associated with their HIV and parenting. Literature reviews were conducted to identify published research and practice guidelines addressing parenting or becoming parents among HIV-infected AYA in the United States. Research articles or practice guidelines on this topic were not identified. Given the paucity of information available on this topic, this article provides a framework for the development of appropriate interventions and guidelines for use in clinical and community-based settings. First, the social, economic, and sexual and reproductive health challenges facing HIV-infected AYA in the United States are summarized. Next, family planning considerations, including age-appropriate disclosure of HIV status to those who are perinatally infected, and contraceptive and preconception counseling are described. The impact of early childbearing on young parents is discussed and considerations are outlined during the preconception, antenatal, and postnatal periods with regard to antiretroviral medications and clinical care guidelines. The importance of transitioning AYA from pediatric or adolescent to adult-centered medical care is highlighted. Finally, a comprehensive approach is suggested that addresses not only medical needs but also emphasizes ways to mitigate the impact of social and economic factors on the health and well-being of these young parents and their children. JF - AIDS Patient Care and STDs AU - Hatfield-Timajchy, Kendra AU - Brown, Jennifer L AU - Haddad, Lisa B AU - Chakraborty, Rana AU - Kourtis, Athena P AD - Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia. Y1 - 2016/07// PY - 2016 DA - July 2016 SP - 315 EP - 323 PB - Mary Ann Liebert, Inc., 2 Madison Ave Larchmont NY 10538 United States VL - 30 IS - 7 SN - 1087-2914, 1087-2914 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1859486690?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+Patient+Care+and+STDs&rft.atitle=Parenting+Among+Adolescents+and+Young+Adults+with+Human+Immunodeficiency+Virus+Infection+in+the+United+States%3A+Challenges%2C+Unmet+Needs%2C+and+Opportunities&rft.au=Hatfield-Timajchy%2C+Kendra%3BBrown%2C+Jennifer+L%3BHaddad%2C+Lisa+B%3BChakraborty%2C+Rana%3BKourtis%2C+Athena+P&rft.aulast=Hatfield-Timajchy&rft.aufirst=Kendra&rft.date=2016-07-01&rft.volume=30&rft.issue=7&rft.spage=315&rft.isbn=&rft.btitle=&rft.title=AIDS+Patient+Care+and+STDs&rft.issn=10872914&rft_id=info:doi/10.1089%2Fapc.2016.0067 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2017-01-01 N1 - Number of references - 65 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1089/apc.2016.0067 ER - TY - JOUR T1 - Age-Related Changes in Immunological Factors and Their Relevance in Allergic Disease Development During Childhood AN - 1837333991; PQ0003767457 AB - Purpose Allergic diseases are triggered by Th2-mediated immune reactions to allergens and orchestrated by various immunological factors, including immune cells and cytokines. Although many reports have suggested that childhood is the critical period in the onset of allergic diseases and aging leads to alter the susceptibility of an individual to allergic diseases, age-related changes in various immunological factors in healthy individuals as well as their difference between healthy and allergic children have not yet been established. Methods We investigated the ratio of Th1/Th2 cells and the levels of 22 allergy-related cytokines across all age groups in individuals who were classified as clinically non-atopic and healthy. We also examined their differences between healthy and allergic children to evaluate immunological changes induced by the development of allergic diseases during childhood. Results The Th1/Th2 ratio rose gradually during the growth period including childhood, reaching peak values in the twenties-thirties age group. Th1/Th2 ratios were significantly lower in allergic children than in healthy controls, whereas 14 of 22 cytokines were significantly higher in allergic children than in healthy controls. On the other hand, there were no differences in Th1/Th2 ratios and cytokines between healthy and allergic adolescents. Conclusions In this study, age-related changes in Th1/Th2 ratios were found in normal controls across all age groups, and decreases in Th1/Th2 ratio were observed with increasing of 14 cytokines in allergic children. The results of this study may be helpful as reference values for both monitoring immunological changes according to aging in healthy individuals and distinguishing between normal and allergic subjects in terms of immune cells and soluble factors. JF - Allergy, Asthma & Immunology Research AU - Chang, Woo-Sung AU - Kim, Eun-Jin AU - Lim, Yeon-Mi AU - Yoon, Dankyu AU - Son, Jo-Young AU - Park, Jung-Won AU - Hong, Soo-Jong AU - Cho, Sang-Heon AU - Lee, Joo-Shil AD - Division of Allergy and Chronic Respiratory Disease, Center for Biomedical Sciences, Korea National Institute of Health, Korea Center for Disease Control and Prevention, Cheongju, Korea, jooshil@korea.kr Y1 - 2016/07// PY - 2016 DA - July 2016 SP - 338 EP - 345 PB - Korean Academy of Asthma, Allergy and Clinical Immunology VL - 8 IS - 4 SN - 2092-7355, 2092-7355 KW - Toxicology Abstracts; Immunology Abstracts KW - Allergy KW - Th1/Th2 ratio KW - cytokine KW - chemokine KW - childhood KW - Age KW - Allergic diseases KW - Helper cells KW - Adolescence KW - Allergens KW - Aging KW - Lymphocytes T KW - Cytokines KW - Children KW - Critical period KW - X 24490:Other UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1837333991?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Allergy%2C+Asthma+%26+Immunology+Research&rft.atitle=Age-Related+Changes+in+Immunological+Factors+and+Their+Relevance+in+Allergic+Disease+Development+During+Childhood&rft.au=Chang%2C+Woo-Sung%3BKim%2C+Eun-Jin%3BLim%2C+Yeon-Mi%3BYoon%2C+Dankyu%3BSon%2C+Jo-Young%3BPark%2C+Jung-Won%3BHong%2C+Soo-Jong%3BCho%2C+Sang-Heon%3BLee%2C+Joo-Shil&rft.aulast=Chang&rft.aufirst=Woo-Sung&rft.date=2016-07-01&rft.volume=8&rft.issue=4&rft.spage=338&rft.isbn=&rft.btitle=&rft.title=Allergy%2C+Asthma+%26+Immunology+Research&rft.issn=20927355&rft_id=info:doi/10.4168%2Faair.2016.8.4.338 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-11-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Age; Allergic diseases; Allergens; Adolescence; Helper cells; Aging; Lymphocytes T; Cytokines; Critical period; Children DO - http://dx.doi.org/10.4168/aair.2016.8.4.338 ER - TY - JOUR T1 - Biological and Epidemiological Features of Antibiotic-Resistant Streptococcus pneumoniae in Pre- and Post-Conjugate Vaccine Eras: a United States Perspective AN - 1811898282; PQ0003494092 JF - Clinical Microbiology Reviews AU - Kim, Lindsay AU - McGee, Lesley AU - Tomczyk, Sara AU - Beall, Bernard AD - << + $0, bbeall@cdc.gov. Y1 - 2016/07// PY - 2016 DA - July 2016 SP - 525 EP - 552 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 29 IS - 3 SN - 0893-8512, 0893-8512 KW - Microbiology Abstracts B: Bacteriology KW - Streptococcus pneumoniae KW - Vaccines KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1811898282?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+Microbiology+Reviews&rft.atitle=Biological+and+Epidemiological+Features+of+Antibiotic-Resistant+Streptococcus+pneumoniae+in+Pre-+and+Post-Conjugate+Vaccine+Eras%3A+a+United+States+Perspective&rft.au=Kim%2C+Lindsay%3BMcGee%2C+Lesley%3BTomczyk%2C+Sara%3BBeall%2C+Bernard&rft.aulast=Kim&rft.aufirst=Lindsay&rft.date=2016-07-01&rft.volume=29&rft.issue=3&rft.spage=525&rft.isbn=&rft.btitle=&rft.title=Clinical+Microbiology+Reviews&rft.issn=08938512&rft_id=info:doi/10.1128%2FCMR.00058-15 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-08-01 N1 - Number of references - 307 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Vaccines; Streptococcus pneumoniae DO - http://dx.doi.org/10.1128/CMR.00058-15 ER - TY - JOUR T1 - Limitations, depressive symptoms, and quality of life among a population-based sample of young adults with congenital heart defects AN - 1808711894; PQ0003484085 AB - Background Little population-based data exist on limitations and health-related quality of life (HRQoL) in adults with congenital heart defects (CHD). Methods We used 2004 to 2012 Medical Expenditure Panel Survey data to identify a population-based sample of young adults ages 18 to 40 years reporting health symptoms or healthcare encounters in the previous year. Comparing adults reporting CHD to others, we examined the prevalence of cognitive, physical, and activity limitations, depressive symptoms, and physical and mental HRQoL. We used chi square tests to examine differences in demographic characteristics, logistic regression to generate adjusted prevalence ratios (aPR), and linear regression to examine HRQoL. Multivariable associations were adjusted for sex, age, race/ethnicity, and smoking status. All analyses were conducted in SUDAAN using weights to account for clustering within sampling units and nonresponse. Results Fifty-nine adults reported CHD (weighted prevalence=0.1%; representing 700,000 U.S. adults from 2004 to 2012 or, on average, 80,000 per year) and 54,011 did not. No demographic characteristics differed significantly by CHD status except health insurance; 31.5% of adults with CHD, compared with 11.0% without, reported public insurance (p=0.01). Compared with their counterparts, adults reporting CHD had a higher prevalence of cognitive (aPR=2.7, 95% confidence interval (CI): 1.0, 7.2), physical (aPR=4.0, 95% CI: 1.9, 8.2), and activity limitations (aPR=4.8, 95% CI: 2.6, 9.1), and poorer physical HRQoL (p=0.004). No differences were observed in depressive symptoms and mental HRQoL by CHD status. Conclusion Physical health and cognitive abilities of adults with CHD were compromised compared with adults without CHD. Birth Defects Research (Part A) 106:580-586, 2016. JF - Birth Defects Research Part A: Clinical and Molecular Teratology AU - Farr, Sherry L AU - Oster, Matthew E AU - Simeone, Regina M AU - Gilboa, Suzanne M AU - Honein, Margaret A AD - Division of Birth Defects and Developmental Disabilities, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. Y1 - 2016/07// PY - 2016 DA - July 2016 SP - 580 EP - 586 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 106 IS - 7 SN - 1542-0752, 1542-0752 KW - Toxicology Abstracts KW - Demography KW - Heart KW - Smoking KW - Age KW - Depression KW - Data processing KW - Cognitive ability KW - Congenital defects KW - Sampling KW - Ethnic groups KW - Quality of life KW - X 24380:Social Poisons & Drug Abuse UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808711894?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Birth+Defects+Research+Part+A%3A+Clinical+and+Molecular+Teratology&rft.atitle=Limitations%2C+depressive+symptoms%2C+and+quality+of+life+among+a+population-based+sample+of+young+adults+with+congenital+heart+defects&rft.au=Farr%2C+Sherry+L%3BOster%2C+Matthew+E%3BSimeone%2C+Regina+M%3BGilboa%2C+Suzanne+M%3BHonein%2C+Margaret+A&rft.aulast=Farr&rft.aufirst=Sherry&rft.date=2016-07-01&rft.volume=106&rft.issue=7&rft.spage=580&rft.isbn=&rft.btitle=&rft.title=Birth+Defects+Research+Part+A%3A+Clinical+and+Molecular+Teratology&rft.issn=15420752&rft_id=info:doi/10.1002%2Fbdra.23498 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-08-17 N1 - SubjectsTermNotLitGenreText - Heart; Demography; Smoking; Age; Data processing; Depression; Cognitive ability; Congenital defects; Sampling; Ethnic groups; Quality of life DO - http://dx.doi.org/10.1002/bdra.23498 ER - TY - JOUR T1 - Red Blood Cell Folate Insufficiency among nonpregnant Women of Childbearing age in Guatemala 2009 to 2010: Prevalence and predicted Neural Tube Defects risk AN - 1808706761; PQ0003484086 AB - Background The World Health Organization recently released recommendations stating that red blood cell (RBC) folate concentrations should be above 400 ng/L (906 nmol/L) for optimal prevention of folate-sensitive neural tube defects (NTDs). The objective of this study was to determine the distribution of folate insufficiency (FI) (<906 nmol/L) and potential risk of NTDs based on RBC folate concentrations among nonpregnant women of child-bearing age in Guatemala. Methods A national and regional multistage cluster probability survey was completed during 2009 to 2010 among Guatemalan women of child-bearing age 15 to 49 years of age. Demographic and health information and blood samples for RBC folate analyses were collected from 1473 women. Prevalence rate ratios of FI and predicted NTD prevalence were estimated based on RBC folate concentrations comparing subpopulations of interest. Results National FI prevalence was 47.2% [95% confidence interval, 43.3-51.1] and showed wide variation by region (18-81%). In all regions, FI prevalence was higher among indigenous (27-89%) than among nonindigenous populations (16-44%). National NTD risk based on RBC folate concentrations was estimated to be 14 per 10,000 live births (95% uncertainty interval, 11.1-18.6) and showed wide regional variation (from 11 NTDS in the Metropolitan region to 26 NTDs per 10,000 live births in the Norte region). Conclusion FI remains a common problem in populations with limited access to fortified products, specifically rural, low income, and indigenous populations. However, among subpopulations that are most likely to have fortified food, the prevalence of FI is similar to countries with well-established fortification programs. Birth Defects Research (Part A) 106:587-595, 2016. JF - Birth Defects Research Part A: Clinical and Molecular Teratology AU - Rosenthal, Jorge AU - Reeve, Mary-Elizabeth AU - Ramirez, Nicte AU - Crider, Krista S AU - Sniezek, Joe AU - Vellozzi, Claudia AU - Devine, Owen AU - Lopez-Pazos, Eunice AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. Y1 - 2016/07// PY - 2016 DA - July 2016 SP - 587 EP - 595 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 106 IS - 7 SN - 1542-0752, 1542-0752 KW - Toxicology Abstracts KW - Demography KW - Age KW - Food KW - Erythrocytes KW - Congenital defects KW - Folic acid KW - Neural tube defects KW - X 24490:Other UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808706761?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Birth+Defects+Research+Part+A%3A+Clinical+and+Molecular+Teratology&rft.atitle=Red+Blood+Cell+Folate+Insufficiency+among+nonpregnant+Women+of+Childbearing+age+in+Guatemala+2009+to+2010%3A+Prevalence+and+predicted+Neural+Tube+Defects+risk&rft.au=Rosenthal%2C+Jorge%3BReeve%2C+Mary-Elizabeth%3BRamirez%2C+Nicte%3BCrider%2C+Krista+S%3BSniezek%2C+Joe%3BVellozzi%2C+Claudia%3BDevine%2C+Owen%3BLopez-Pazos%2C+Eunice&rft.aulast=Rosenthal&rft.aufirst=Jorge&rft.date=2016-07-01&rft.volume=106&rft.issue=7&rft.spage=587&rft.isbn=&rft.btitle=&rft.title=Birth+Defects+Research+Part+A%3A+Clinical+and+Molecular+Teratology&rft.issn=15420752&rft_id=info:doi/10.1002%2Fbdra.23499 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-08-17 N1 - SubjectsTermNotLitGenreText - Demography; Age; Food; Erythrocytes; Congenital defects; Folic acid; Neural tube defects DO - http://dx.doi.org/10.1002/bdra.23499 ER - TY - JOUR T1 - C-reactive protein increases with gestational age during pregnancy among Chinese women AN - 1808697928; PQ0003483914 AB - Objective To examine the concentration of C-reactive protein (CRP) in relation to gestational weeks during pregnancy among Chinese women. Methods From a randomized control trial of prenatal supplementation with folic acid, iron-folic acid, and multiple micronutrients in China, we examined 834 pregnant women with CRP measured initially between 5 and 20 weeks and at follow-up between 28 and 32 weeks gestation. We calculated and plotted CRP geometric means by gestational weeks. The same analysis was repeated for women who had normal pregnancies (624 women) by excluding women with stillbirth, preterm, small for gestational age, body mass index 30 kg/m super(2) at enrollment, and hypertension or anemia during pregnancy. Results We observed a significant positive trend between log-transformed CRP and gestational age from 5 to 20 weeks and from 28 to 32 weeks both in the full sample and in the subset of women who had normal pregnancies. CRP geometric mean was 0.81 mg/l at 5-7 weeks of gestation, 2.85 mg/l at 19-20 weeks of gestation, and 3.89 mg/l at 32 weeks of gestation. A similar increasing trend in the CRP median or percentage of elevated CRP were also observed. Conclusion We concluded that CRP increased with gestational age among healthy Chinese women who delivered healthy infants. Am. J. Hum. Biol. 28:574-579, 2016. JF - American Journal of Human Biology AU - Mei, Zuguo AU - Li, Hongtian AU - Serdula, Mary K AU - Flores-Ayala, RAFAEL C AU - Wang, Linlin AU - Liu, Jian-Meng AU - Grummer-Strawn, Laurence M AD - Division of Nutrition, Physical Activity and Obesity, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia. Y1 - 2016/07// PY - 2016 DA - July 2016 SP - 574 EP - 579 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 28 IS - 4 SN - 1042-0533, 1042-0533 KW - Physical Education Index; Environment Abstracts KW - Measurement KW - Age KW - Prenatal experience KW - Body mass KW - Women KW - Anemia KW - Health KW - Pregnancy KW - Low-birth-weight KW - Objectives KW - Analysis KW - Proteins KW - China, People's Rep. KW - Females KW - Micronutrients KW - Folic acid KW - Trends KW - Infants KW - Hypertension KW - ENA 08:International KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808697928?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Human+Biology&rft.atitle=C-reactive+protein+increases+with+gestational+age+during+pregnancy+among+Chinese+women&rft.au=Mei%2C+Zuguo%3BLi%2C+Hongtian%3BSerdula%2C+Mary+K%3BFlores-Ayala%2C+RAFAEL+C%3BWang%2C+Linlin%3BLiu%2C+Jian-Meng%3BGrummer-Strawn%2C+Laurence+M&rft.aulast=Mei&rft.aufirst=Zuguo&rft.date=2016-07-01&rft.volume=28&rft.issue=4&rft.spage=574&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Human+Biology&rft.issn=10420533&rft_id=info:doi/10.1002%2Fajhb.22837 LA - English DB - Physical Education Index; ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-09-01 N1 - SubjectsTermNotLitGenreText - Measurement; Analysis; Objectives; Women; Proteins; Health; Trends; Hypertension; Pregnancy; Age; Prenatal experience; Low-birth-weight; Body mass; Anemia; Micronutrients; Females; Folic acid; Infants; China, People's Rep. DO - http://dx.doi.org/10.1002/ajhb.22837 ER - TY - JOUR T1 - Antibody Levels and Protection After Hepatitis B Vaccine: Results of a 30-Year Follow-up Study and Response to a Booster Dose AN - 1808685610; PQ0003326204 AB - Background.The duration of protection in children and adults resulting from hepatitis B vaccination is unknown. In 1981, we immunized a cohort of 1578 Alaska Native adults and children from 15 Alaska communities aged > or =6 months using 3 doses of plasma-derived hepatitis B vaccine. Methods.Persons were tested for antibody to hepatitis B surface antigen (anti-HBs) levels 30 years after receiving the primary series. Those with levels or =10 mIU/mL. Among participants with anti-HBs levels or =10 mIU/mL at 30 days. Initial anti-HBs level after the primary series was correlated with higher anti-HBs levels at 30 years. Conclusions.Based on anti-HBs level > or =10 mIU/mL at 30 years and an 88% booster dose response, we estimate that > or =90% of participants had evidence of protection 30 years later. Booster doses are not needed. JF - Journal of Infectious Diseases AU - Bruce, Michael G AU - Bruden, Dana AU - Hurlburt, Debby AU - Zanis, Carolyn AU - Thompson, Gail AU - Rea, Lisa AU - Toomey, Michele AU - Townshend-Bulson, Lisa AU - Rudolph, Karen AU - Bulkow, Lisa AU - Spradling, Philip R AU - Baum, Richard AU - Hennessy, Thomas AU - McMahon, Brian J AD - Arctic Investigations Program, Division of Preparedness and Emerging Infections, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, zwa8@cdc.gov Y1 - 2016/07/01/ PY - 2016 DA - 2016 Jul 01 SP - 16 EP - 22 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 214 IS - 1 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Immunology Abstracts; Health & Safety Science Abstracts KW - hepatitis B KW - immunogenicity KW - Alaska Native KW - plasma-derived vaccine KW - Alaska KW - US KW - cohort KW - 30 years KW - antibody KW - anti-HBs KW - Antibodies KW - Hepatitis B virus KW - Infectious diseases KW - INE, USA, Alaska KW - Hepatitis B surface antigen KW - Vaccines KW - Children KW - Vaccination KW - V 22350:Immunology KW - F 06905:Vaccines KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808685610?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Antibody+Levels+and+Protection+After+Hepatitis+B+Vaccine%3A+Results+of+a+30-Year+Follow-up+Study+and+Response+to+a+Booster+Dose&rft.au=Bruce%2C+Michael+G%3BBruden%2C+Dana%3BHurlburt%2C+Debby%3BZanis%2C+Carolyn%3BThompson%2C+Gail%3BRea%2C+Lisa%3BToomey%2C+Michele%3BTownshend-Bulson%2C+Lisa%3BRudolph%2C+Karen%3BBulkow%2C+Lisa%3BSpradling%2C+Philip+R%3BBaum%2C+Richard%3BHennessy%2C+Thomas%3BMcMahon%2C+Brian+J&rft.aulast=Bruce&rft.aufirst=Michael&rft.date=2016-07-01&rft.volume=214&rft.issue=1&rft.spage=16&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiv748 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-09-01 N1 - SubjectsTermNotLitGenreText - Antibodies; Hepatitis B surface antigen; Vaccines; Children; Vaccination; Infectious diseases; Hepatitis B virus; INE, USA, Alaska DO - http://dx.doi.org/10.1093/infdis/jiv748 ER - TY - JOUR T1 - Tetanus Immunity among Women Aged 15 to 39 Years in Cambodia: a National Population-Based Serosurvey, 2012 AN - 1808645754; PQ0003406198 AB - To monitor progress toward maternal and neonatal tetanus elimination (MNTE) in Cambodia, we conducted a nationwide serosurvey of tetanus immunity in 2012. Multistage cluster sampling was used to select 2,154 women aged 15 to 39 years. Tetanus toxoid antibodies in serum samples were measured by gold-standard double-antigen enzyme-linked immunosorbent assay (DAE) and a novel multiplex bead assay (MBA). Antibody concentrations of greater than or equal to 0.01 IU/ml by DAE or the equivalent for MBA were considered seroprotective. Estimated tetanus seroprotection was 88% (95% confidence interval [CI], 86 to 89%); 64% (95% CI, 61 to 67%) of women had antibody levels of greater than or equal to 1.0 IU/ml. Seroprotection was significantly lower (P < 0.001) among women aged 15 to 19 years (63%) and 20 to 24 years (87%) than among those aged greater than or equal to 25 years (96%), among nulliparous women than among parous women (71 versus 97%), and among those living in the western region than among those living in other regions (82 versus 89%). The MBA showed high sensitivity (99% [95% CI, 98 to 99%]) and specificity (92% [95% CI, 88 to 95%]) compared with DAE. Findings were compatible with MNTE in Cambodia ( greater than or equal to 80% protection). Tetanus immunity gaps should be addressed through strengthened routine immunization and targeted vaccination campaigns. Incorporating tetanus testing in national serosurveys using MBAs, which can measure immunity to multiple pathogens simultaneously, may be beneficial for monitoring MNTE. JF - Clinical and Vaccine Immunology AU - Scobie, Heather M AU - Mao, Bunsoth AU - Buth, Sokhal AU - Wannemuehler, Kathleen A AU - Soerensen, Charlotte AU - Kannarath, Chheng AU - Jenks, M Harley AU - Moss, Delynn M AU - Priest, Jeffrey W AU - Soeung, Sann Chan AD - << + $0, hscobie@cdc.gov. Y1 - 2016/07// PY - 2016 DA - July 2016 SP - 546 EP - 554 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 23 IS - 7 SN - 1556-6811, 1556-6811 KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Antibodies KW - Enzyme-linked immunosorbent assay KW - Immunity KW - Neonates KW - Pathogens KW - Sampling KW - Vaccines KW - Tetanus KW - Vaccination KW - F 06905:Vaccines KW - J 02350:Immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808645754?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+and+Vaccine+Immunology&rft.atitle=Tetanus+Immunity+among+Women+Aged+15+to+39+Years+in+Cambodia%3A+a+National+Population-Based+Serosurvey%2C+2012&rft.au=Scobie%2C+Heather+M%3BMao%2C+Bunsoth%3BButh%2C+Sokhal%3BWannemuehler%2C+Kathleen+A%3BSoerensen%2C+Charlotte%3BKannarath%2C+Chheng%3BJenks%2C+M+Harley%3BMoss%2C+Delynn+M%3BPriest%2C+Jeffrey+W%3BSoeung%2C+Sann+Chan&rft.aulast=Scobie&rft.aufirst=Heather&rft.date=2016-07-01&rft.volume=23&rft.issue=7&rft.spage=546&rft.isbn=&rft.btitle=&rft.title=Clinical+and+Vaccine+Immunology&rft.issn=15566811&rft_id=info:doi/10.1128%2FCVI.00052-16 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Number of references - 42 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Enzyme-linked immunosorbent assay; Antibodies; Vaccines; Sampling; Pathogens; Neonates; Immunity; Tetanus; Vaccination DO - http://dx.doi.org/10.1128/CVI.00052-16 ER - TY - JOUR T1 - Zika Virus Disease in Travelers Returning to the United States, 2010-2014 AN - 1808636917; PQ0003465327 AB - Zika virus is an emerging mosquito-borne flavivirus that typically causes a mild febrile illness with rash, arthralgia, or conjunctivitis. Zika virus has recently caused large outbreaks of disease in southeast Asia, Pacific Ocean Islands, and the Americas. We identified all positive Zika virus test results performed at U.S. Centers for Disease Control and Prevention from 2010 to 2014. For persons with test results indicating a recent infection with Zika virus, we collected information on demographics, travel history, and clinical features. Eleven Zika virus disease cases were identified among travelers returning to the United States. The median age of cases was 50 years (range: 29-74 years) and six (55%) were male. Nine (82%) cases had their illness onset from January to April. All cases reported a travel history to islands in the Pacific Ocean during the days preceding illness onset, and all cases were potentially viremic while in the United States. Public health prevention messages about decreasing mosquito exposure, preventing sexual exposure, and preventing infection in pregnant women should be targeted to individuals traveling to or living in areas with Zika virus activity. Health-care providers and public health officials should be educated about the recognition, diagnosis, and prevention of Zika virus disease. JF - American Journal of Tropical Medicine and Hygiene AU - Hennessey, Morgan J AU - Fischer, Marc AU - Panella, Amanda J AU - Kosoy, Olga I AU - Laven, Janeen J AU - Lanciotti, Robert S AU - Staples, J Erin AD - Arboviral Diseases Branch, Centers for Disease Control and Prevention (CDC), Fort Collins, Colorado, estaples@cdc.gov Y1 - 2016/07// PY - 2016 DA - July 2016 SP - 212 EP - 215 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 95 IS - 1 SN - 0002-9637, 0002-9637 KW - Virology & AIDS Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Travel KW - Historical account KW - Age KW - Zika virus KW - Viruses KW - Disease control KW - Infection KW - Flavivirus KW - Public health KW - Demography KW - Exanthema KW - Islands KW - I, Pacific KW - Arthralgia KW - Biological surveys KW - Conjunctivitis KW - Pregnancy KW - I, Central Pacific, Pacific Ocean Is. KW - Prevention KW - Oceans KW - Outbreaks KW - ISEW, Southeast Asia KW - Hygiene KW - K 03400:Human Diseases KW - Q1 08485:Species interactions: pests and control KW - H 12000:Epidemiology and Public Health KW - Q5 08524:Public health, medicines, dangerous organisms KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808636917?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Zika+Virus+Disease+in+Travelers+Returning+to+the+United+States%2C+2010-2014&rft.au=Hennessey%2C+Morgan+J%3BFischer%2C+Marc%3BPanella%2C+Amanda+J%3BKosoy%2C+Olga+I%3BLaven%2C+Janeen+J%3BLanciotti%2C+Robert+S%3BStaples%2C+J+Erin&rft.aulast=Hennessey&rft.aufirst=Morgan&rft.date=2016-07-01&rft.volume=95&rft.issue=1&rft.spage=212&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.16-0049 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Biological surveys; Disease control; Hygiene; Public health; Demography; Travel; Exanthema; Age; Islands; Oceans; Conjunctivitis; Infection; Arthralgia; Pregnancy; Historical account; Viruses; Prevention; Outbreaks; Zika virus; Flavivirus; I, Central Pacific, Pacific Ocean Is.; I, Pacific; ISEW, Southeast Asia DO - http://dx.doi.org/10.4269/ajtmh.16-0049 ER - TY - JOUR T1 - Rapid Antimicrobial Susceptibility Testing of Bacillus anthracis, Yersinia pestis, and Burkholderia pseudomallei by Use of Laser Light Scattering Technology AN - 1846404536; PQ0003246979 AB - Rapid methods to determine antimicrobial susceptibility would assist in the timely distribution of effective treatment or postexposure prophylaxis in the aftermath of the release of bacterial biothreat agents such as Bacillus anthracis, Yersinia pestis, or Burkholderia pseudomallei. Conventional susceptibility tests require 16 to 48 h of incubation, depending on the bacterial species. We evaluated a method that is based on laser light scattering technology that measures cell density in real time. We determined that it has the ability to rapidly differentiate between growth (resistant) and no growth (susceptible) of several bacterial threat agents in the presence of clinically relevant antimicrobials. Results were available in 10 h of incubation. Use of laser scattering technology decreased the time required to determine antimicrobial susceptibility by 50% to 75% for B. anthracis, Y. pestis, and B. pseudomallei compared to conventional methods. JF - Journal of Clinical Microbiology AU - Bugrysheva, Julia V AU - Lascols, Christine AU - Sue, David AU - Weigel, Linda M Y1 - 2016/06// PY - 2016 DA - June 2016 SP - 1462 EP - 1471 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 54 IS - 6 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1846404536?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Rapid+Antimicrobial+Susceptibility+Testing+of+Bacillus+anthracis%2C+Yersinia+pestis%2C+and+Burkholderia+pseudomallei+by+Use+of+Laser+Light+Scattering+Technology&rft.au=Bugrysheva%2C+Julia+V%3BLascols%2C+Christine%3BSue%2C+David%3BWeigel%2C+Linda+M&rft.aulast=Chiantore&rft.aufirst=Mariachiara&rft.date=2006-05-01&rft.volume=29&rft.issue=6&rft.spage=467&rft.isbn=&rft.btitle=&rft.title=Polar+Biology&rft.issn=07224060&rft_id=info:doi/10.1007%2Fs00300-005-0077-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-12-01 N1 - Number of references - 32 N1 - Last updated - 2016-12-07 DO - http://dx.doi.org/10.1128/JCM.03251-15 ER - TY - JOUR T1 - Infant and maternal risk factors related to necrotising enterocolitis-associated infant death in the United States AN - 1811897394; PQ0003082159 AB - Aim To evaluate necrotising enterocolitis (NEC)-associated infant death and identify risk factors related to NEC infant death in the United States. Methods The United States Period Linked Birth/Infant Death data for 2010-2013 were utilised to determine risk factors associated with NEC infant death. Infant mortality rates (IMRs) were calculated and a retrospective matched case-control analysis was performed. An infant case was defined as having the International Classification of Diseases, Tenth Revision code for NEC listed on the death record. Controls were matched on birthweight and randomly selected. Conditional multivariable logistic regression models stratified by birthweight were conducted to determine risk factors for NEC infant death. Results The average annual NEC IMR was 12.5 deaths per 100 000 live births and was higher among very low birthweight (VLBW) compared to normal birthweight infants and among black compared to white infants. For VLBW infants, the multivariable analysis identified male sex, five-minute Apgar score of less than 7, and white infants born to a mother who is less than or equal to 19 years of age to be related with NEC-associated infant death. Conclusion Paediatricians should be aware of the factors related to NEC-associated infant death to reduce the number of infants at greatest risk for NEC and focus on racial disparities. JF - Acta Paediatrica AU - Seeman, Sara M AU - Mehal, Jason M AU - Haberling, Dana L AU - Holman, Robert C AU - Stoll, Barbara J AD - Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA. Y1 - 2016/06// PY - 2016 DA - June 2016 SP - e240 EP - e246 PB - Wiley-Blackwell Publishing, 9600 Garsington Rd Oxford United Kingdom VL - 105 IS - 6 SN - 0803-5253, 0803-5253 KW - Physical Education Index KW - Death KW - Classification KW - Blacks KW - Risk factors KW - Analysis KW - Diseases KW - Sex KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1811897394?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Acta+Paediatrica&rft.atitle=Infant+and+maternal+risk+factors+related+to+necrotising+enterocolitis-associated+infant+death+in+the+United+States&rft.au=Seeman%2C+Sara+M%3BMehal%2C+Jason+M%3BHaberling%2C+Dana+L%3BHolman%2C+Robert+C%3BStoll%2C+Barbara+J&rft.aulast=Seeman&rft.aufirst=Sara&rft.date=2016-06-01&rft.volume=105&rft.issue=6&rft.spage=e240&rft.isbn=&rft.btitle=&rft.title=Acta+Paediatrica&rft.issn=08035253&rft_id=info:doi/10.1111%2Fapa.13390 LA - English DB - Physical Education Index N1 - Date revised - 2016-08-01 N1 - Last updated - 2016-09-01 N1 - SubjectsTermNotLitGenreText - Death; Classification; Blacks; Analysis; Risk factors; Diseases; Sex DO - http://dx.doi.org/10.1111/apa.13390 ER - TY - JOUR T1 - Advanced Molecular Detection of Malarone Resistance AN - 1808723406; PQ0003229746 AB - The rapid emergence of drug-resistant malaria parasites during the course of an infection remains a major challenge for providing accurate treatment guidelines. This is particularly important in cases of malaria treatment failure. Using a previously well-characterized case of malaria treatment failure, we show the utility of using next-generation sequencing for early detection of the rise and selection of a previously reported atovaquone-proguanil (malarone) drug resistance-associated mutation. JF - Antimicrobial Agents & Chemotherapy AU - Talundzic, Eldin AU - Plucinski, Mateusz M AU - Biliya, Shweta AU - Silva-Flannery, Luciana M AU - Arguin, Paul M AU - Halsey, Eric S AU - Barnwell, John W AU - Vannberg, Fredrik AU - Udhayakumar, Venkatachalam AD - << + $0, etalundzic@cdc.gov. Y1 - 2016/06// PY - 2016 DA - June 2016 SP - 3821 EP - 3823 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 60 IS - 6 SN - 0066-4804, 0066-4804 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Parasites KW - Human diseases KW - Mutations KW - Drug resistance KW - Disease control KW - Malaria KW - Infection KW - Public health KW - Mutation KW - Drugs KW - A 01340:Antibiotics & Antimicrobials KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808723406?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Advanced+Molecular+Detection+of+Malarone+Resistance&rft.au=Talundzic%2C+Eldin%3BPlucinski%2C+Mateusz+M%3BBiliya%2C+Shweta%3BSilva-Flannery%2C+Luciana+M%3BArguin%2C+Paul+M%3BHalsey%2C+Eric+S%3BBarnwell%2C+John+W%3BVannberg%2C+Fredrik%3BUdhayakumar%2C+Venkatachalam&rft.aulast=Talundzic&rft.aufirst=Eldin&rft.date=2016-06-01&rft.volume=60&rft.issue=6&rft.spage=3821&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.00171-16 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Number of references - 16 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Parasites; Human diseases; Mutations; Disease control; Malaria; Drugs; Public health; Drug resistance; Infection; Mutation DO - http://dx.doi.org/10.1128/AAC.00171-16 ER - TY - JOUR T1 - Persistence of Influenza A (H1N1) Virus on Stainless Steel Surfaces AN - 1808721756; PQ0003229838 AB - As annual influenza epidemics continue to cause significant morbidity and economic burden, an understanding of viral persistence and transmission is critical for public health officials and health care workers to better protect patients and their family members from infection. The infectivity and persistence of two influenza A (H1N1) virus strains (A/New Caledonia/20/1999 and A/Brisbane/59/2007) on stainless steel (SS) surfaces were evaluated using three different surface matrices (2% fetal bovine serum, 5 mg/ml mucin, and viral medium) under various absolute humidity conditions (4.1 105 mPa, 6.5 105 mPa, 7.1 105 mPa, 11.4 105 mPa, 11.2 105 mPa, and 17.9 105 mPa) for up to 7 days. Influenza A virus was deposited onto SS coupons (7.07 cm2) and recovered by agitation and sonication in viral medium. Viral persistence was quantified using a tissue culture-based enzyme-linked immunosorbent assay (ELISA) to determine the median (50%) tissue culture infective dose (TCID50) of infectious virus per coupon. Overall, both strains of influenza A virus remained infectious on SS coupons, with an approximate 2 log10 loss over 7 days. Factors that influenced viral persistence included absolute humidity, strain-absolute humidity interaction, and time (P less than or equal to 0.01). Further studies on the transfer of influenza A virus from fomites by hand and the impact of inanimate surface contamination on transmission should be performed, as this study demonstrates prolonged persistence on nonporous surfaces. IMPORTANCE This study tested the ability of two influenza A (H1N1) virus strains to persist and remain infectious on stainless steel surfaces under various environmental conditions. It demonstrated that influenza A (H1N1) viruses can persist and remain infectious on stainless steel surfaces for 7 days. Additional studies should be conducted to assess the role played by contaminated surfaces in the transmission of influenza A virus. JF - Antimicrobial Agents & Chemotherapy AU - Perry, K A AU - Coulliette, A D AU - Rose, L J AU - Shams, A M AU - Edwards, J R AU - Noble-Wang, J A AD - << + $0, KPerry@cdc.gov. Y1 - 2016/06// PY - 2016 DA - June 2016 SP - 3239 EP - 3245 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 82 IS - 11 SN - 0099-2240, 0099-2240 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Contamination KW - Influenza A KW - Viruses KW - Absolute humidity KW - Infection KW - Medical personnel KW - Morbidity KW - Public health KW - Mucins KW - Influenza KW - Influenza A virus KW - Economics KW - mucin KW - Steel KW - Enzyme-linked immunosorbent assay KW - Epidemics KW - Hand KW - Humidity KW - Tissue culture KW - Sonication KW - Fomites KW - Infectivity KW - ISEW, Pacific, New Caledonia KW - Environmental conditions KW - Immunoassays KW - Australia, Queensland, Brisbane KW - stainless steel KW - H 1000:Occupational Safety and Health KW - V 22400:Human Diseases KW - A 01300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808721756?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Persistence+of+Influenza+A+%28H1N1%29+Virus+on+Stainless+Steel+Surfaces&rft.au=Perry%2C+K+A%3BCoulliette%2C+A+D%3BRose%2C+L+J%3BShams%2C+A+M%3BEdwards%2C+J+R%3BNoble-Wang%2C+J+A&rft.aulast=Perry&rft.aufirst=K&rft.date=2016-06-01&rft.volume=82&rft.issue=11&rft.spage=3239&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00992240&rft_id=info:doi/10.1128%2FAEM.04046-15 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Number of references - 39 N1 - Last updated - 2016-08-04 N1 - SubjectsTermNotLitGenreText - Enzyme-linked immunosorbent assay; Epidemics; Contamination; Influenza A; Humidity; Hand; Tissue culture; Infection; Morbidity; Medical personnel; Public health; Fomites; Sonication; Infectivity; Economics; mucin; Environmental conditions; stainless steel; Viruses; Absolute humidity; Influenza; Mucins; Steel; Immunoassays; Influenza A virus; ISEW, Pacific, New Caledonia; Australia, Queensland, Brisbane DO - http://dx.doi.org/10.1128/AEM.04046-15 ER - TY - JOUR T1 - Genomic Resolution of Outbreak-Associated Legionella pneumophila Serogroup 1 Isolates from New York State AN - 1808713594; PQ0003229849 AB - A total of 30 Legionella pneumophila serogroup 1 isolates representing 10 separate legionellosis laboratory investigations ("outbreaks") that occurred in New York State between 2004 and 2012 were selected for evaluation of whole-genome sequencing (WGS) approaches for molecular subtyping of this organism. Clinical and environmental isolates were available for each outbreak and were initially examined by pulsed-field gel electrophoresis (PFGE). Sequence-based typing alleles were extracted from WGS data yielding complete sequence types (ST) for isolates representing 8 out of the 10 outbreaks evaluated in this study. Isolates from separate outbreaks sharing the same ST also contained the fewest differences in core genome single nucleotide polymorphisms (SNPs) and the greatest proportion of identical allele sequences in a whole-genome multilocus sequence typing (wgMLST) scheme. Both core SNP and wgMLST analyses distinguished isolates from separate outbreaks, including those from two outbreaks sharing indistinguishable PFGE profiles. Isolates from a hospital-associated outbreak spanning multiple years shared indistinguishable PFGE profiles but displayed differences in their genome sequences, suggesting the presence of multiple environmental sources. Finally, the rtx gene demonstrated differences in the repeat region sequence among ST1 isolates from different outbreaks, suggesting that variation in this gene may be useful for targeted molecular subtyping approaches for L. pneumophila. This study demonstrates the utility of various genome sequence analysis approaches for L. pneumophila for environmental source attribution studies while furthering the understanding of Legionella ecology. IMPORTANCE We demonstrate that whole-genome sequencing helps to improve resolution of Legionella pneumophila isolated during laboratory investigations of legionellosis compared to traditional subtyping methods. These data can be important in confirming the environmental sources of legionellosis outbreaks. Moreover, we evaluated various methods to analyze genome sequence data to help resolve outbreak-related isolates. JF - Antimicrobial Agents & Chemotherapy AU - Raphael, Brian H AU - Baker, Deborah J AU - Nazarian, Elizabeth AU - Lapierre, Pascal AU - Bopp, Dianna AU - Kozak-Muiznieks, Natalia A AU - Morrison, Shatavia S AU - Lucas, Claressa E AU - Mercante, Jeffrey W AU - Musser, Kimberlee A AD - << + $0, jwinchell@cdc.gov. Y1 - 2016/06// PY - 2016 DA - June 2016 SP - 3582 EP - 3590 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 82 IS - 12 SN - 0099-2240, 0099-2240 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Genomes KW - Legionella pneumophila KW - Data processing KW - Typing KW - Single-nucleotide polymorphism KW - Nucleotide sequence KW - Pulsed-field gel electrophoresis KW - genomics KW - multilocus sequence typing KW - A 01340:Antibiotics & Antimicrobials KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808713594?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Genomic+Resolution+of+Outbreak-Associated+Legionella+pneumophila+Serogroup+1+Isolates+from+New+York+State&rft.au=Raphael%2C+Brian+H%3BBaker%2C+Deborah+J%3BNazarian%2C+Elizabeth%3BLapierre%2C+Pascal%3BBopp%2C+Dianna%3BKozak-Muiznieks%2C+Natalia+A%3BMorrison%2C+Shatavia+S%3BLucas%2C+Claressa+E%3BMercante%2C+Jeffrey+W%3BMusser%2C+Kimberlee+A&rft.aulast=Raphael&rft.aufirst=Brian&rft.date=2016-06-01&rft.volume=82&rft.issue=12&rft.spage=3582&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Number of references - 28 N1 - Last updated - 2016-09-01 N1 - SubjectsTermNotLitGenreText - Genomes; Typing; Data processing; Single-nucleotide polymorphism; Nucleotide sequence; Pulsed-field gel electrophoresis; genomics; multilocus sequence typing; Legionella pneumophila DO - http://dx.doi.org/10.1128/AEM.00362-16 ER - TY - JOUR T1 - Improving Capture of Vaccine History: Case Study from an Evaluation of 10-Valent Pneumococcal Conjugate Vaccine Introduction in Kenya AN - 1808639784; PQ0003290542 AB - With the accelerated introduction of new vaccines in low-income settings, understanding immunization program performance is critical. We sought to improve immunization history acquisition from Ministry of Health vaccination cards during a vaccine impact study of 10-valent pneumococcal conjugate vaccine on pneumococcal carriage among young children in Kenya in 2012 and 2013. We captured immunization history in a low proportion of study participants in 2012 using vaccination cards. To overcome this challenge, we implemented a household-based reminder system in 2013 using community health workers (CHWs), and increased the retrieval of vaccine cards from 62% in 2012 to 89% in 2013 (P< 0.001). The home-based reminder system using CHWs is an example of an approach that improved immunization history data quality in a resource-poor setting. JF - American Journal of Tropical Medicine and Hygiene AU - Harris, Aaron M AU - Aol, George AU - Ouma, Dominic AU - Bigogo, Godfrey AU - Montgomery, Joel M AU - Whitney, Cynthia G AU - Breiman, Robert F AU - Kim, Lindsay AD - Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, ieo9@cdc.gov Y1 - 2016/06// PY - 2016 DA - June 2016 SP - 1400 EP - 1402 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 94 IS - 6 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Historical account KW - Data processing KW - Disease control KW - Socioeconomics KW - Children KW - Vaccination KW - Immunization KW - Workers KW - Streptococcus pneumoniae KW - Kenya KW - Case studies KW - Reminder KW - Vaccines KW - Hygiene KW - K 03400:Human Diseases KW - Q5 08504:Effects on organisms KW - J 02350:Immunology KW - Q1 08604:Stock assessment and management KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808639784?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Improving+Capture+of+Vaccine+History%3A+Case+Study+from+an+Evaluation+of+10-Valent+Pneumococcal+Conjugate+Vaccine+Introduction+in+Kenya&rft.au=Harris%2C+Aaron+M%3BAol%2C+George%3BOuma%2C+Dominic%3BBigogo%2C+Godfrey%3BMontgomery%2C+Joel+M%3BWhitney%2C+Cynthia+G%3BBreiman%2C+Robert+F%3BKim%2C+Lindsay&rft.aulast=Harris&rft.aufirst=Aaron&rft.date=2016-06-01&rft.volume=94&rft.issue=6&rft.spage=1400&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.15-0783 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Disease control; Vaccines; Hygiene; Vaccination; Immunization; Workers; Data processing; Reminder; Children; Historical account; Case studies; Socioeconomics; Streptococcus pneumoniae; Kenya DO - http://dx.doi.org/10.4269/ajtmh.15-0783 ER - TY - JOUR T1 - Chikungunya and Dengue Virus Infections Among United States Community Service Volunteers Returning from the Dominican Republic, 2014 AN - 1808615664; PQ0003290532 AB - Chikungunya spread throughout the Dominican Republic (DR) after the first identified laboratory-confirmed cases were reported in April 2014. In June 2014, a U.S.-based service organization operating in the DR reported chikungunya-like illnesses among several staff. We assessed the incidence of chikungunya virus (CHIKV) and dengue virus (DENV) infection and illnesses and evaluated adherence to mosquito avoidance measures among volunteers/staff deployed in the DR who returned to the United States during July-August 2014. Investigation participants completed a questionnaire that collected information on demographics, medical history, self-reported illnesses, and mosquito exposures and avoidance behaviors and provided serum for CHIKV and DENV diagnostic testing by reverse transcription polymerase chain reaction and IgM enzyme-linked immunosorbent assay. Of 102 participants, 42 (41%) had evidence of recent CHIKV infection and two (2%) had evidence of recent DENV infection. Of the 41 participants with evidence of recent CHIKV infection only, 39 (95%) reported fever, 37 (90%) reported rash, and 37 (90%) reported joint pain during their assignment. All attended the organization's health trainings, and 89 (87%) sought a pretravel health consultation. Most (~95%) used insect repellent; however, only 30% applied it multiple times daily and < 5% stayed in housing with window/door screens. In sum, CHIKV infections were common among these volunteers during the 2014 chikungunya epidemic in the DR. Despite high levels of preparation, reported adherence to mosquito avoidance measures were inconsistent. Clinicians should discuss chikungunya with travelers visiting areas with ongoing CHIKV outbreaks and should consider chikungunya when diagnosing febrile illnesses in travelers returning from affected areas. JF - American Journal of Tropical Medicine and Hygiene AU - Millman, Alexander J AU - Esposito, Douglas H AU - Biggs, Holly M AU - Decenteceo, Michelle AU - Klevos, Andrew AU - Hunsperger, Elizabeth AU - Munoz-Jordan, Jorge AU - Kosoy, Olga I AU - McPherson, Heidi AU - Sullivan, Carmen AD - Centers for Disease Control and Prevention, Atlanta, Georgia, irm6@cdc.gov Y1 - 2016/06// PY - 2016 DA - June 2016 SP - 1336 EP - 1341 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 94 IS - 6 SN - 0002-9637, 0002-9637 KW - Virology & AIDS Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Dengue virus KW - Historical account KW - Human diseases KW - Housing KW - Nucleotide sequence KW - Viruses KW - Avoidance reactions KW - Pain KW - Infection KW - Reverse transcription KW - Public health KW - Demography KW - Fever KW - Exanthema KW - Repellents KW - Polymerase chain reaction KW - Biological surveys KW - Inventories KW - Enzyme-linked immunosorbent assay KW - Chikungunya virus KW - Epidemics KW - Training KW - Avoidance behavior KW - Transcription KW - Pest control KW - Pest outbreaks KW - Insects KW - Joints KW - USA KW - Dominican Republic KW - Outbreaks KW - Hygiene KW - Immunoassays KW - Immunoglobulin M KW - K 03400:Human Diseases KW - Q1 08604:Stock assessment and management KW - Q5 08524:Public health, medicines, dangerous organisms KW - H 0500:General KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808615664?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Chikungunya+and+Dengue+Virus+Infections+Among+United+States+Community+Service+Volunteers+Returning+from+the+Dominican+Republic%2C+2014&rft.au=Millman%2C+Alexander+J%3BEsposito%2C+Douglas+H%3BBiggs%2C+Holly+M%3BDecenteceo%2C+Michelle%3BKlevos%2C+Andrew%3BHunsperger%2C+Elizabeth%3BMunoz-Jordan%2C+Jorge%3BKosoy%2C+Olga+I%3BMcPherson%2C+Heidi%3BSullivan%2C+Carmen&rft.aulast=Millman&rft.aufirst=Alexander&rft.date=2016-06-01&rft.volume=94&rft.issue=6&rft.spage=1336&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.15-0815 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Biological surveys; Human diseases; Epidemics; Nucleotide sequence; Transcription; Avoidance reactions; Pest control; Hygiene; Public health; Inventories; Enzyme-linked immunosorbent assay; Housing; Avoidance behavior; Pain; Infection; Pest outbreaks; Reverse transcription; Joints; Fever; Demography; Exanthema; Repellents; Polymerase chain reaction; Immunoglobulin M; Historical account; Training; Viruses; Outbreaks; Immunoassays; Insects; Dengue virus; Chikungunya virus; USA; Dominican Republic DO - http://dx.doi.org/10.4269/ajtmh.15-0815 ER - TY - JOUR T1 - Molecular Characterizations of Surface Proteins Hemagglutinin and Neuraminidase from Recent H5Nx Avian Influenza Viruses AN - 1808612563; PQ0003247020 AB - During 2014, a subclade 2.3.4.4 highly pathogenic avian influenza (HPAI) A(H5N8) virus caused poultry outbreaks around the world. In late 2014/early 2015, the virus was detected in wild birds in Canada and the United States, and these viruses also gave rise to reassortant progeny, composed of viral RNA segments (vRNAs) from both Eurasian and North American lineages. In particular, viruses were found with N1, N2, and N8 neuraminidase vRNAs, and these are collectively referred to as H5Nx viruses. In the United States, more than 48 million domestic birds have been affected. Here we present a detailed structural and biochemical analysis of the surface antigens of H5N1, H5N2, and H5N8 viruses in addition to those of a recent human H5N6 virus. Our results with recombinant hemagglutinin reveal that these viruses have a strict avian receptor binding preference, while recombinantly expressed neuraminidases are sensitive to FDA-approved and investigational antivirals. Although H5Nx viruses currently pose a low risk to humans, it is important to maintain surveillance of these circulating viruses and to continually assess future changes that may increase their pandemic potential. IMPORTANCE The H5Nx viruses emerging in North America, Europe, and Asia pose a great public health concern. Here we report a molecular and structural study of the major surface proteins of several H5Nx influenza viruses. Our results improve the understanding of these new viruses and provide important information on their receptor preferences and susceptibilities to antivirals, which are central to pandemic risk assessment. JF - Journal of Virology AU - Yang, Hua AU - Carney, Paul J AU - Mishin, Vasiliy P AU - Guo, Zhu AU - Chang, Jessie C AU - Wentworth, David E AU - Gubareva, Larisa V AU - Stevens, James Y1 - 2016/06// PY - 2016 DA - June 2016 SP - 5770 EP - 5784 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 90 IS - 12 SN - 0022-538X, 0022-538X KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Risk assessment KW - Poultry KW - Hemagglutinins KW - Viruses KW - Biochemical analysis KW - Public health KW - Influenza KW - pandemics KW - ANE, Europe KW - Risk factors KW - Exo- alpha -sialidase KW - Asia KW - ANW, Canada KW - Fowl plague KW - USA KW - RNA KW - surface antigens KW - Proteins KW - Progeny KW - Outbreaks KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - V 22310:Genetics, Taxonomy & Structure UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808612563?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Virology&rft.atitle=Molecular+Characterizations+of+Surface+Proteins+Hemagglutinin+and+Neuraminidase+from+Recent+H5Nx+Avian+Influenza+Viruses&rft.au=Yang%2C+Hua%3BCarney%2C+Paul+J%3BMishin%2C+Vasiliy+P%3BGuo%2C+Zhu%3BChang%2C+Jessie+C%3BWentworth%2C+David+E%3BGubareva%2C+Larisa+V%3BStevens%2C+James&rft.aulast=Yang&rft.aufirst=Hua&rft.date=2016-06-01&rft.volume=90&rft.issue=12&rft.spage=5770&rft.isbn=&rft.btitle=&rft.title=Journal+of+Virology&rft.issn=0022538X&rft_id=info:doi/10.1128%2FJVI.00180-16 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Number of references - 75 N1 - Last updated - 2016-08-04 N1 - SubjectsTermNotLitGenreText - Risk assessment; Fowl plague; Poultry; pandemics; RNA; surface antigens; Risk factors; Hemagglutinins; Biochemical analysis; Progeny; Exo- alpha -sialidase; Public health; Influenza; Viruses; Proteins; Outbreaks; USA; ANE, Europe; ANW, Canada; Asia DO - http://dx.doi.org/10.1128/JVI.00180-16 ER - TY - JOUR T1 - Cost-effectiveness of seasonal inactivated influenza vaccination among pregnant women AN - 1808610060; PQ0003264670 AB - Objective To evaluate the cost-effectiveness of seasonal inactivated influenza vaccination among pregnant women using data from three recent influenza seasons in the United States. Design, setting, and participants We developed a decision-analytic model following a cohort of 5.2 million pregnant women and their infants aged <6 months to evaluate the cost-effectiveness of vaccinating women against seasonal influenza during pregnancy from a societal perspective. The main outcome measures were quality-adjusted life-year (QALY) gained and cost-effectiveness ratios. Data sources included surveillance data, epidemiological studies, and published vaccine cost data. Sensitivity analyses were also performed. All costs and outcomes were discounted at 3% annually. Main outcome measures Total costs (direct and indirect), effects (QALY gains, averted case numbers), and incremental cost-effectiveness of seasonal inactivated influenza vaccination among pregnant women (cost per QALY gained). Results Using a recent benchmark of 52.2% vaccination coverage among pregnant women, we studied a hypothetical cohort of 2,753,015 vaccinated pregnant women. With an estimated vaccine effectiveness of 73% among pregnant women and 63% among infants <6 months, QALY gains for each season were 305 (2010-2011), 123 (2011-2012), and 610 (2012-2013). Compared with no vaccination, seasonal influenza vaccination during pregnancy was cost-saving when using data from the 2010-2011 and 2012-2013 influenza seasons. The cost-effectiveness ratio was greater than $100,000/QALY with the 2011-2012 influenza season data, when CDC reported a low attack rate compared to other recent seasons. Conclusions Influenza vaccination for pregnant women can reduce morbidity from influenza in both pregnant women and their infants aged <6 months. Seasonal influenza vaccination during pregnancy is cost-saving during moderate to severe influenza seasons. JF - Vaccine AU - Xu, Jing AU - Zhou, Fangjun AU - Reed, Carrie AU - Chaves, Sandra S AU - Messonnier, Mark AU - Kim, Inkyu K AD - Immunization Service Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, USA Y1 - 2016/06// PY - 2016 DA - June 2016 SP - 3149 EP - 3155 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 34 IS - 27 SN - 0264-410X, 0264-410X KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts; Immunology Abstracts KW - Seasonal influenza vaccination KW - Cost-effectiveness analysis KW - Pregnancy KW - Data processing KW - Vaccination KW - Cost benefit analysis KW - Morbidity KW - Models KW - Influenza KW - USA KW - Sulfur dioxide KW - Sensitivity analysis KW - Females KW - Vaccines KW - Benchmarks KW - Seasonal variations KW - Infants KW - V 22400:Human Diseases KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808610060?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Cost-effectiveness+of+seasonal+inactivated+influenza+vaccination+among+pregnant+women&rft.au=Xu%2C+Jing%3BZhou%2C+Fangjun%3BReed%2C+Carrie%3BChaves%2C+Sandra+S%3BMessonnier%2C+Mark%3BKim%2C+Inkyu+K&rft.aulast=Xu&rft.aufirst=Jing&rft.date=2016-06-01&rft.volume=34&rft.issue=27&rft.spage=3149&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/10.1016%2Fj.vaccine.2016.04.057 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Number of references - 43 N1 - Last updated - 2016-08-04 N1 - SubjectsTermNotLitGenreText - Influenza; Data processing; Vaccines; Vaccination; Morbidity; Models; Infants; Pregnancy; Sulfur dioxide; Sensitivity analysis; Females; Benchmarks; Seasonal variations; Cost benefit analysis; USA DO - http://dx.doi.org/10.1016/j.vaccine.2016.04.057 ER - TY - JOUR T1 - The Use of Economic Evaluation to Inform Newborn Screening Policy Decisions: The Washington State Experience AN - 1794162500 AB - Policy Points: Newborn screening not only saves lives but can also yield net societal economic benefit, in addition to benefits such as improved quality of life to affected individuals and families. Calculations of net economic benefit from newborn screening include the monetary equivalent of avoided deaths and reductions in costs of care for complications associated with late-diagnosed individuals minus the additional costs of screening, diagnosis, and treatment associated with prompt diagnosis. Since 2001 the Washington State Department of Health has successfully implemented an approach to conducting evidence-based economic evaluations of disorders proposed for addition to the state-mandated newborn screening panel. Context Economic evaluations can inform policy decisions on the expansion of newborn screening panels. This article documents the use of cost-benefit models in Washington State as part of the rule-making process that resulted in the implementation of screening for medium-chain acyl-CoA dehydrogenase (MCAD) deficiency and 4 other metabolic disorders in 2004, cystic fibrosis (CF) in 2006, 15 other metabolic disorders in 2008, and severe combined immune deficiency (SCID) in 2014. Methods We reviewed Washington State Department of Health internal reports and spreadsheet models of expected net societal benefit of adding disorders to the state newborn screening panel. We summarize the assumptions and findings for 2 models (MCAD and CF) and discuss them in relation to findings in the peer-reviewed literature. Findings The MCAD model projected a benefit-cost ratio of 3.4 to 1 based on assumptions of a 20.0 percentage point reduction in infant mortality and a 13.9 percentage point reduction in serious developmental disability. The CF model projected a benefit-cost ratio of 4.0-5.4 to 1 for a discount rate of 3%-4% and a plausible range of 1-2 percentage point reductions in deaths up to age 10 years. Conclusions The Washington State cost-benefit models of newborn screening were broadly consistent with peer-reviewed literature, and their findings of net benefit appear to be robust to uncertainty in parameters. Public health newborn screening programs can develop their own capacity to project expected costs and benefits of expansion of newborn screening panels, although it would be most efficient if this capacity were shared among programs. JF - The Milbank Quarterly AU - Grosse, SCOTT D AU - Thompson, JOHN D AU - Ding, YAO AU - Glass, MICHAEL AD - Centers for Disease Control and Prevention, National Center on Birth Defects and Developmental Disabilities ; Washington State Department of Health, Office of Newborn Screening ; Association of Public Health Laboratories ; Washington State Department of Health, Office of Newborn Screening; Deceased Y1 - 2016/06// PY - 2016 DA - Jun 2016 SP - 366 EP - 391 CY - Oxford PB - Wiley Subscription Services, Inc. VL - 94 IS - 2 SN - 0887-378X KW - Political Science KW - Medical screening KW - Costs KW - Cystic fibrosis KW - Metabolic disorders KW - Cystic KW - Uncertainty KW - Parameters KW - Mortality KW - Infant mortality KW - Cost benefit analysis KW - Quality of life KW - Disability KW - Screening KW - Health costs KW - Diagnosis KW - Cost analysis KW - Evidence based medicine KW - Public health KW - Public health policy KW - Public Health KW - Infant Mortality KW - Family Life KW - Cost-Benefit Analysis KW - Disorders KW - Health Care Services Policy KW - Quality of Life KW - Maternal and Infant Welfare KW - Handicapped KW - Rules and Practice KW - Implementation KW - Disability Recipients UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1794162500?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Milbank+Quarterly&rft.atitle=The+Use+of+Economic+Evaluation+to+Inform+Newborn+Screening+Policy+Decisions%3A+The+Washington+State+Experience&rft.au=Grosse%2C+SCOTT+D%3BThompson%2C+JOHN+D%3BDing%2C+YAO%3BGlass%2C+MICHAEL&rft.aulast=Grosse&rft.aufirst=SCOTT&rft.date=2016-06-01&rft.volume=94&rft.issue=2&rft.spage=366&rft.isbn=&rft.btitle=&rft.title=The+Milbank+Quarterly&rft.issn=0887378X&rft_id=info:doi/10.1111%2F1468-0009.12196 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA); PAIS Index N1 - Copyright - Copyright© 2016 Milbank Memorial Fund N1 - Last updated - 2016-06-21 DO - http://dx.doi.org/10.1111/1468-0009.12196 ER - TY - JOUR T1 - Impact and Cost-effectiveness of 3 Doses of 9-Valent Human Papillomavirus (HPV) Vaccine Among US Females Previously Vaccinated With 4-Valent HPV Vaccine AN - 1790950034; PQ0003120231 AB - Background.We estimated the potential impact and cost-effectiveness of providing 3-doses of nonavalent human papillomavirus (HPV) vaccine (9vHPV) to females aged 13-18 years who had previously completed a series of quadrivalent HPV vaccine (4vHPV), a strategy we refer to as "additional 9vHPV vaccination." Methods.We used 2 distinct models: (1) the simplified model, which is among the most basic of the published dynamic HPV models, and (2) the US HPV-ADVISE model, a complex, stochastic, individual-based transmission-dynamic model. Results.When assuming no 4vHPV cross-protection, the incremental cost per quality-adjusted life-year (QALY) gained by additional 9vHPV vaccination was $146 200 in the simplified model and $108 200 in the US HPV-ADVISE model ($191 800 when assuming 4vHPV cross-protection). In 1-way sensitivity analyses in the scenario of no 4vHPV cross-protection, the simplified model results ranged from $70 300 to $182 000, and the US HPV-ADVISE model results ranged from $97 600 to $118 900. Conclusions.The average cost per QALY gained by additional 9vHPV vaccination exceeded $100 000 in both models. However, the results varied considerably in sensitivity and uncertainty analyses. Additional 9vHPV vaccination is likely not as efficient as many other potential HPV vaccination strategies, such as increasing primary 9vHPV vaccine coverage. JF - Journal of Infectious Diseases AU - Chesson, Harrell W AU - Laprise, Jean-Francois AU - Brisson, Marc AU - Markowitz, Lauri E AD - Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, hChesson@cdc.gov Y1 - 2016/06/01/ PY - 2016 DA - 2016 Jun 01 SP - 1694 EP - 1700 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 213 IS - 11 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - human papillomavirus KW - vaccine KW - cost-effectiveness analysis KW - vaccine impact KW - disease transmission models KW - Sensitivity KW - Cross-protection KW - Vaccination KW - Stochasticity KW - Cost benefit analysis KW - Models KW - Stochastic models KW - Sensitivity analysis KW - Infectious diseases KW - Females KW - Vaccines KW - Human papillomavirus KW - V 22490:Miscellaneous KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1790950034?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Impact+and+Cost-effectiveness+of+3+Doses+of+9-Valent+Human+Papillomavirus+%28HPV%29+Vaccine+Among+US+Females+Previously+Vaccinated+With+4-Valent+HPV+Vaccine&rft.au=Chesson%2C+Harrell+W%3BLaprise%2C+Jean-Francois%3BBrisson%2C+Marc%3BMarkowitz%2C+Lauri+E&rft.aulast=Chesson&rft.aufirst=Harrell&rft.date=2016-06-01&rft.volume=213&rft.issue=11&rft.spage=1694&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiw046 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-05-01 N1 - Last updated - 2016-08-03 N1 - SubjectsTermNotLitGenreText - Cross-protection; Vaccines; Stochasticity; Vaccination; Models; Sensitivity; Stochastic models; Infectious diseases; Sensitivity analysis; Females; Cost benefit analysis; Human papillomavirus DO - http://dx.doi.org/10.1093/infdis/jiw046 ER - TY - JOUR T1 - In vitro antiviral activity of adenosine analog NITD008 against tick-borne flaviviruses. AN - 1786126486; 27016316 AB - There are currently no antiviral therapies available for the tick-borne flaviviruses associated with hemorrhagic fevers: Kyasanur Forest disease virus (KFDV), both classical and the Alkhurma hemorrhagic fever virus (AHFV) subtype, and Omsk hemorrhagic fever virus (OHFV). In this brief study, we describe the in vitro antiviral activity of adenosine analog NITD008 against KFDV, AHFV, OHFV, as well as Tick-borne Encephalitis virus (TBEV). Alongside the well-established activity of NITD008 against mosquito-borne flaviviruses, our results have demonstrated the feasibility of identifying nucleoside analog inhibitors that have pan-flavivirus activity. Published by Elsevier B.V. JF - Antiviral research AU - Lo, Michael K AU - Shi, Pei-Yong AU - Chen, Yen-Liang AU - Flint, Mike AU - Spiropoulou, Christina F AD - Viral Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: mko2@cdc.gov. ; Department of Biochemistry and Molecular Biology, Department of Phamarcology and Toxicology, Sealy Center for Structural Biology & Molecular Biophysics, University of Texas Medical Branch, Galveston, TX, USA; Novartis Institute for Tropical Diseases, Singapore. Electronic address: peshi@utmb.edu. ; Novartis Institute for Tropical Diseases, Singapore. ; Viral Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA. ; Viral Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: ccs8@cdc.gov. Y1 - 2016/06// PY - 2016 DA - June 2016 SP - 46 EP - 49 VL - 130 KW - Index Medicus KW - Antiviral KW - Tick-borne KW - NITD008 KW - Nucleoside analog KW - Flavivirus UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1786126486?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antiviral+research&rft.atitle=In%C2%A0vitro+antiviral+activity+of+adenosine+analog+NITD008+against+tick-borne+flaviviruses.&rft.au=Lo%2C+Michael+K%3BShi%2C+Pei-Yong%3BChen%2C+Yen-Liang%3BFlint%2C+Mike%3BSpiropoulou%2C+Christina+F&rft.aulast=Lo&rft.aufirst=Michael&rft.date=2016-06-01&rft.volume=130&rft.issue=&rft.spage=46&rft.isbn=&rft.btitle=&rft.title=Antiviral+research&rft.issn=1872-9096&rft_id=info:doi/10.1016%2Fj.antiviral.2016.03.013 LA - English DB - ProQuest Environmental Science Collection N1 - Date created - 2016-05-01 N1 - Date revised - 2017-01-14 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1016/j.antiviral.2016.03.013 ER - TY - JOUR T1 - Zika Virus and Birth Defects--Reviewing the Evidence for Causality. AN - 1790465432; 27074377 JF - The New England journal of medicine AU - Rasmussen, Sonja A AU - Jamieson, Denise J AU - Honein, Margaret A AU - Petersen, Lyle R AD - From the Division of Public Health Information Dissemination, Center for Surveillance, Epidemiology, and Laboratory Services (S.A.R.), Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion (D.J.J.), and Division of Congenital and Developmental Disorders, National Center on Birth Defects and Developmental Disabilities (M.A.H.), Centers for Disease Control and Prevention, Atlanta; and the Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO (L.R.P.). Y1 - 2016/05/19/ PY - 2016 DA - 2016 May 19 SP - 1981 EP - 1987 VL - 374 IS - 20 KW - Abridged Index Medicus KW - Index Medicus KW - Causality KW - Humans KW - Brazil -- epidemiology KW - Zika Virus KW - Microcephaly -- epidemiology KW - Zika Virus Infection -- complications KW - Microcephaly -- virology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1790465432?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+New+England+journal+of+medicine&rft.atitle=Zika+Virus+and+Birth+Defects--Reviewing+the+Evidence+for+Causality.&rft.au=Rasmussen%2C+Sonja+A%3BJamieson%2C+Denise+J%3BHonein%2C+Margaret+A%3BPetersen%2C+Lyle+R&rft.aulast=Rasmussen&rft.aufirst=Sonja&rft.date=2016-05-19&rft.volume=374&rft.issue=20&rft.spage=1981&rft.isbn=&rft.btitle=&rft.title=The+New+England+journal+of+medicine&rft.issn=1533-4406&rft_id=info:doi/10.1056%2FNEJMsr1604338 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2016-06-03 N1 - Date created - 2016-05-19 N1 - Date revised - 2017-01-14 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1056/NEJMsr1604338 ER - TY - JOUR T1 - Meningococcal vaccination for international travellers from Greece visiting developing countries AN - 1808634776; PQ0003320996 AB - Background Meningococcal meningitis is a serious disease. Travel-associated infection for the general traveller is low; however regular epidemics in indigenous population, particularly in sub-Saharan Africa are responsible for significant morbidity and mortality. Our aim was to assess meningococcal vaccination for international travellers from Greece. Methods A prospective questionnaire-based study was conducted during 2009-2013. Results A total of 5283 travellers were studied (median age: 39.2 years); Meningococcal tetravalent vaccine (A,C,W135,Y) was delivered to 1150 (21.8%) of them. Of those who travelled to the Middle East and sub-Saharan Africa, 73.1% and 21.2% received meningococcal vaccine, respectively. Of those travellers who travelled to sub-Saharan Africa from November to June and from July to October, 22.1% and 20.6% were vaccinated with meningococcal vaccine, respectively. Of all travellers who travelled for <1 month and greater than or equal to 1 month, 23.3%, and 20.5%, were vaccinated, respectively. Meningococcal vaccine was administered to 95.3% of pilgrims, 17.4% of those visiting friends and relatives (VFRs), 16.7% of those who travelled for recreation, and 13.8% of those who travelled for work. Of travellers who stayed in urban, in rural, and in urban and rural areas, 32%, 11.6% and 12.7% were vaccinated, respectively. Meningococcal vaccine was delivered to 29.2%, 21.1%, 19.4% and 5.1% of those who stayed in hotels, at local people's home, in camps, and on ships, respectively. The association of meningococcal vaccine administration with the destination, duration and purpose of travel, area of stay and type of accommodation was statistically significant. Conclusion There is a need to improve meningococcal vaccine recommendations for travellers from Greece, particularly for high risk populations, such as VFRs, business travellers and those visiting sub-Saharan Africa especially during the dry season. JF - Travel Medicine and Infectious Disease AU - Pavli, Androula AU - Katerelos, Panagiotis AU - Smeti, Paraskevi AU - Maltezou, Helena C AD - Travel Medicine Office, Hellenic Center for Disease Control and Prevention, Athens, Greece Y1 - 2016/05// PY - 2016 DA - May 2016 SP - 261 EP - 266 PB - Elsevier VL - 14 IS - 3 SN - 1477-8939, 1477-8939 KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Pre-travel KW - Meningitis KW - Vaccination KW - Travellers KW - Travel KW - Mortality KW - Age KW - Epidemics KW - Cyclic AMP KW - Statistical analysis KW - Neisseria meningitidis KW - Infection KW - Morbidity KW - Recreation KW - Risk factors KW - Vaccines KW - Developing countries KW - F 06905:Vaccines KW - J 02350:Immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808634776?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Contribution+of+the+BacT%2FAlert+MB+Mycobacterium+Bottle+to+Bloodstream+Infection+Surveillance+in+Thailand%3A+Added+Yield+for+Burkholderia+pseudomallei&rft.au=Jorakate%2C+Possawat%3BHigdon%2C+Melissa%3BKaewpan%2C+Anek%3BMakprasert%2C+Sirirat%3BYuenprakhon%2C+Somkhit%3BTawisaid%2C+Kittisak%3BDejsirilert%2C+Surang%3BWhistler%2C+Toni%3BBaggett%2C+Henry+C&rft.aulast=Jorakate&rft.aufirst=Possawat&rft.date=2015-03-01&rft.volume=53&rft.issue=3&rft.spage=910&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.02008-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Number of references - 20 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Travel; Mortality; Age; Epidemics; Cyclic AMP; Travellers; Statistical analysis; Infection; Vaccination; Morbidity; Meningitis; Recreation; Risk factors; Vaccines; Developing countries; Neisseria meningitidis DO - http://dx.doi.org/10.1016/j.tmaid.2016.03.001 ER - TY - JOUR T1 - Changes in the medical management of patients on opioid analgesics following a diagnosis of substance abuse AN - 1805493576; PQ0003007119 AB - Purpose When providers recognize that patients are abusing prescription drugs, review of the drugs they are prescribed and attempts to treat the substance use disorder are warranted. However, little is known about whether prescribing patterns change following such a diagnosis. Methods We used national longitudinal health claims data from the Market Scan registered commercial claims database for January 2010-June 2011. We used a cohort of 1.85 million adults 18-64years old prescribed opioid analgesics but without abuse diagnoses during a 6-month "preabuse" period. We identified a subset of 9009 patients receiving diagnoses of abuse of non-illicit drugs (abuse group) during a 6-month "abuse" period and compared them with patients without such a diagnosis (nonabuse group) during both the abuse period and a subsequent 6-month "postabuse" period. Results During the abuse period 5.78% of the abuse group and 0.14% of the nonabuse group overdosed. Overdose rates declined to 2.12% in the abuse group in the postabuse period. Opioid prescribing rates declined 13.5%, and benzodiazepine rates declined 12.3% in the abuse group in the post-abuse period. Antidepressants and gabapentin were prescribed to roughly one half and one quarter of the abuse group, respectively, during all three periods. Daily opioid dosage did not decline in the abuse group following diagnosis. Conclusions Prescribing to people who abuse drugs changes little after their abuse is documented. Actions such as tapering opioid and benzodiazepine prescriptions, maximizing alternative treatments for pain, and greater use of medication-assisted treatment such as buprenorphine could help reduce risk in this population. JF - Pharmacoepidemiology and Drug Safety AU - Paulozzi, Leonard J AU - Zhou, Chao AU - Jones, Christopher M AU - Xu, Likang AU - Florence, Curtis S AD - National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, USA. Y1 - 2016/05// PY - 2016 DA - May 2016 SP - 545 EP - 552 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 25 IS - 5 SN - 1053-8569, 1053-8569 KW - Toxicology Abstracts KW - gabapentin KW - Antidepressants KW - Databases KW - Overdose KW - Buprenorphine KW - Data processing KW - Benzodiazepine KW - Opioids KW - Pain KW - Analgesics KW - Drug abuse KW - X 24380:Social Poisons & Drug Abuse UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1805493576?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Pharmacoepidemiology+and+Drug+Safety&rft.atitle=Changes+in+the+medical+management+of+patients+on+opioid+analgesics+following+a+diagnosis+of+substance+abuse&rft.au=Paulozzi%2C+Leonard+J%3BZhou%2C+Chao%3BJones%2C+Christopher+M%3BXu%2C+Likang%3BFlorence%2C+Curtis+S&rft.aulast=Paulozzi&rft.aufirst=Leonard&rft.date=2016-05-01&rft.volume=25&rft.issue=5&rft.spage=545&rft.isbn=&rft.btitle=&rft.title=Pharmacoepidemiology+and+Drug+Safety&rft.issn=10538569&rft_id=info:doi/10.1002%2Fpds.3980 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-08-17 N1 - SubjectsTermNotLitGenreText - gabapentin; Databases; Antidepressants; Buprenorphine; Overdose; Data processing; Benzodiazepine; Pain; Opioids; Analgesics; Drug abuse DO - http://dx.doi.org/10.1002/pds.3980 ER - TY - JOUR T1 - Multicenter Evaluation of Clinical Diagnostic Methods for Detection and Isolation of Campylobacter spp. from Stool AN - 1794495707; PQ0003096682 AB - The use of culture-independent diagnostic tests (CIDTs), such as stool antigen tests, as standalone tests for the detection of Campylobacter in stool is increasing. We conducted a prospective, multicenter study to evaluate the performance of stool antigen CIDTs compared to culture and PCR for Campylobacter detection. Between July and October 2010, we tested 2,767 stool specimens from patients with gastrointestinal illness with the following methods: four types of Campylobacter selective media, four commercial stool antigen assays, and a commercial PCR assay. Illnesses from which specimens were positive by one or more culture media or at least one CIDT and PCR were designated "cases." A total of 95 specimens (3.4%) met the case definition. The stool antigen CIDTs ranged from 79.6% to 87.6% in sensitivity, 95.9 to 99.5% in specificity, and 41.3 to 84.3% in positive predictive value. Culture alone detected 80/89 (89.9% sensitivity) Campylobacter jejuni/Campylobacter coli-positive cases. Of the 209 noncases that were positive by at least one CIDT, only one (0.48%) was positive by all four stool antigen tests, and 73% were positive by just one stool antigen test. The questionable relevance of unconfirmed positive stool antigen CIDT results was supported by the finding that noncases were less likely than cases to have gastrointestinal symptoms. Thus, while the tests were convenient to use, the sensitivity, specificity, and positive predictive value of Campylobacter stool antigen tests were highly variable. Given the relatively low incidence of Campylobacter disease and the generally poor diagnostic test characteristics, this study calls into question the use of commercially available stool antigen CIDTs as standalone tests for direct detection of Campylobacter in stool. JF - Journal of Clinical Microbiology AU - Fitzgerald, Collette AU - Patrick, Mary AU - Gonzalez, Anthony AU - Akin, Joshua AU - Polage, Christopher R AU - Wymore, Kate AU - Gillim-Ross, Laura AU - Xavier, Karen AU - Sadlowski, Jennifer AU - Monahan, Jan AD - << + $0, chf3@cdc.gov. Y1 - 2016/05// PY - 2016 DA - May 2016 SP - 1209 EP - 1215 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 54 IS - 5 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Campylobacter jejuni KW - Polymerase chain reaction KW - Feces KW - Media (selective) KW - Media (culture) KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1794495707?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Multicenter+Evaluation+of+Clinical+Diagnostic+Methods+for+Detection+and+Isolation+of+Campylobacter+spp.+from+Stool&rft.au=Fitzgerald%2C+Collette%3BPatrick%2C+Mary%3BGonzalez%2C+Anthony%3BAkin%2C+Joshua%3BPolage%2C+Christopher+R%3BWymore%2C+Kate%3BGillim-Ross%2C+Laura%3BXavier%2C+Karen%3BSadlowski%2C+Jennifer%3BMonahan%2C+Jan&rft.aulast=Fitzgerald&rft.aufirst=Collette&rft.date=2016-05-01&rft.volume=54&rft.issue=5&rft.spage=1209&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.01925-15 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-06-01 N1 - Number of references - 26 N1 - Last updated - 2016-07-20 N1 - SubjectsTermNotLitGenreText - Polymerase chain reaction; Feces; Media (selective); Media (culture); Campylobacter jejuni DO - http://dx.doi.org/10.1128/JCM.01925-15 ER - TY - JOUR T1 - Identification of Antigenic Glycans from Schistosoma mansoni by Using a Shotgun Egg Glycan Microarray AN - 1790971878; PQ0003049566 AB - Infection of mammals by the parasitic helminth Schistosoma mansoni induces antibodies to glycan antigens in worms and eggs, but the differential nature of the immune response among infected mammals is poorly understood. To better define these responses, we used a shotgun glycomics approach in which N-glycans from schistosome egg glycoproteins were prepared, derivatized, separated, and used to generate an egg shotgun glycan microarray. This array was interrogated with sera from infected mice, rhesus monkeys, and humans and with glycan-binding proteins and antibodies to gather information about the structures of antigenic glycans, which also were analyzed by mass spectrometry. A major glycan antigen targeted by IgG from different infected species is the FLDNF epitope [Fuc alpha 3GalNAc beta 4(Fuc alpha 3)GlcNAc-R], which is also recognized by the IgG monoclonal antibody F2D2. The FLDNF antigen is expressed by all life stages of the parasite in mammalian hosts, and F2D2 can kill schistosomula in vitro in a complement-dependent manner. Different antisera also recognized other glycan determinants, including core beta -xylose and highly fucosylated glycans. Thus, the natural shotgun glycan microarray of schistosome eggs is useful in identifying antigenic glycans and in developing new anti-glycan reagents that may have diagnostic applications and contribute to developing new vaccines against schistosomiasis. JF - Infection and Immunity AU - Mickum, Megan L AU - Prasanphanich, Nina Salinger AU - Song, Xuezheng AU - Dorabawila, Nelum AU - Mandalasi, Msano AU - Lasanajak, Yi AU - Luyai, Anthony AU - Secor, W Evan AU - Wilkins, Patricia P AU - Die, Irma Van AD - << + $0, kex9@cdc.gov. Y1 - 2016/05// PY - 2016 DA - May 2016 SP - 1371 EP - 1386 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 84 IS - 5 SN - 0019-9567, 0019-9567 KW - Biotechnology and Bioengineering Abstracts; Immunology Abstracts KW - Schistosoma mansoni KW - Parasites KW - Monoclonal antibodies KW - Developmental stages KW - Schistosomiasis KW - Polysaccharides KW - Infection KW - Mass spectroscopy KW - Eggs KW - Antisera KW - N-glycans KW - Immunoglobulin G KW - Macaca mulatta KW - Immune response KW - Vaccines KW - Glycoproteins KW - Epitopes KW - F 06905:Vaccines KW - W 30900:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1790971878?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Infection+and+Immunity&rft.atitle=Identification+of+Antigenic+Glycans+from+Schistosoma+mansoni+by+Using+a+Shotgun+Egg+Glycan+Microarray&rft.au=Mickum%2C+Megan+L%3BPrasanphanich%2C+Nina+Salinger%3BSong%2C+Xuezheng%3BDorabawila%2C+Nelum%3BMandalasi%2C+Msano%3BLasanajak%2C+Yi%3BLuyai%2C+Anthony%3BSecor%2C+W+Evan%3BWilkins%2C+Patricia+P%3BDie%2C+Irma+Van&rft.aulast=Mickum&rft.aufirst=Megan&rft.date=2016-05-01&rft.volume=84&rft.issue=5&rft.spage=1371&rft.isbn=&rft.btitle=&rft.title=Infection+and+Immunity&rft.issn=00199567&rft_id=info:doi/10.1128%2FIAI.01349-15 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-05-01 N1 - Number of references - 84 N1 - Last updated - 2016-08-17 N1 - SubjectsTermNotLitGenreText - Parasites; Monoclonal antibodies; Schistosomiasis; Developmental stages; Infection; Polysaccharides; Eggs; Mass spectroscopy; Antisera; N-glycans; Immunoglobulin G; Glycoproteins; Vaccines; Immune response; Epitopes; Schistosoma mansoni; Macaca mulatta DO - http://dx.doi.org/10.1128/IAI.01349-15 ER - TY - JOUR T1 - Vaccination with 2014-15 Seasonal Inactivated Influenza Vaccine Elicits Cross-Reactive Anti-HA Antibodies with Strong ADCC Against Antigenically Drifted Circulating H3N2 Virus in Humans AN - 1790956482; PQ0003049688 AB - It is well established that virus neutralizing (VN) antibodies to hemagglutinin (HA) antigens of influenza A viruses provide optimal protection against antigenically matched strains of influenza A viruses. In contrast, little is known about the potential role of HA-specific, non-neutralizing antibodies in protection against human influenza illness at present. In this study, we show that individuals vaccinated with the 2014-15 seasonal inactivated influenza vaccine displayed strong A/H3N2 HA-specific antibody-dependent cell-mediated cytotoxicity (ADCC) activities against an antigenically drifted H3N2 virus, despite poor induction of cross-reactive neutralizing antibodies against the antigenic variant. Given that passive transfer of influenza HA-monospecific immune sera with negligible levels of HA-specific VN antibodies can often confer considerable cross protection against lethal challenge with heterologous influenza viruses in animal models, it is conceivable that HA-specific, non-neutralizing antibodies may provide certain degree of cross protection against antigenically drifted influenza A viruses through ADCC in case of influenza vaccine mismatches. This may have important implications for public health. JF - Viral Immunology AU - Zhong, Weimin AU - Gross, FLiaini AU - Holiday, Crystal AU - Jefferson, Stacie N AU - Bai, Yaohui AU - Liu, Feng AU - Katz, Jacqueline M AU - Levine, Min Z AD - Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia. Y1 - 2016/05// PY - 2016 DA - May 2016 SP - 259 EP - 262 PB - Mary Ann Liebert, Inc., 2 Madison Ave Larchmont NY 10538 United States VL - 29 IS - 4 SN - 0882-8245, 0882-8245 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts; Immunology Abstracts KW - Antigenic variants KW - Immunology KW - Influenza A KW - Hemagglutinins KW - Viruses KW - Animal models KW - Vaccination KW - Public health KW - Influenza KW - Cytotoxicity KW - Antibodies KW - Sulfur dioxide KW - Antibody-dependent cell-mediated cytotoxicity KW - Vaccines KW - Seasonal variations KW - V 22350:Immunology KW - F 06905:Vaccines KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1790956482?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Viral+Immunology&rft.atitle=Vaccination+with+2014-15+Seasonal+Inactivated+Influenza+Vaccine+Elicits+Cross-Reactive+Anti-HA+Antibodies+with+Strong+ADCC+Against+Antigenically+Drifted+Circulating+H3N2+Virus+in+Humans&rft.au=Zhong%2C+Weimin%3BGross%2C+FLiaini%3BHoliday%2C+Crystal%3BJefferson%2C+Stacie+N%3BBai%2C+Yaohui%3BLiu%2C+Feng%3BKatz%2C+Jacqueline+M%3BLevine%2C+Min+Z&rft.aulast=Zhong&rft.aufirst=Weimin&rft.date=2016-05-01&rft.volume=29&rft.issue=4&rft.spage=259&rft.isbn=&rft.btitle=&rft.title=Viral+Immunology&rft.issn=08828245&rft_id=info:doi/10.1089%2Fvim.2016.0003 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-05-01 N1 - Number of references - 23 N1 - Last updated - 2016-08-03 N1 - SubjectsTermNotLitGenreText - Antigenic variants; Antibodies; Hemagglutinins; Influenza A; Animal models; Antibody-dependent cell-mediated cytotoxicity; Vaccines; Vaccination; Public health; Influenza; Cytotoxicity; Sulfur dioxide; Immunology; Viruses; Seasonal variations DO - http://dx.doi.org/10.1089/vim.2016.0003 ER - TY - JOUR T1 - Mammalian Pathogenesis and Transmission of H7N9 Influenza Viruses from Three Waves, 2013-2015 AN - 1790955484; PQ0003096748 AB - Three waves of human infection with H7N9 influenza viruses have concluded to date, but only viruses within the first wave (isolated between March and September 2013) have been extensively studied in mammalian models. While second- and third-wave viruses remain closely linked phylogenetically and antigenically, even subtle molecular changes can impart critical shifts in mammalian virulence. To determine if H7N9 viruses isolated from humans during 2013 to 2015 have maintained the phenotype first identified among 2013 isolates, we assessed the ability of first-, second-, and third-wave H7N9 viruses isolated from humans to cause disease in mice and ferrets and to transmit among ferrets. Similar to first-wave viruses, H7N9 viruses from 2013 to 2015 were highly infectious in mice, with lethality comparable to that of the well-studied A/Anhui/1/2013 virus. Second- and third-wave viruses caused moderate disease in ferrets, transmitted efficiently to cohoused, naive contact animals, and demonstrated limited transmissibility by respiratory droplets. All H7N9 viruses replicated efficiently in human bronchial epithelial cells, with subtle changes in pH fusion threshold identified between H7N9 viruses examined. Our results indicate that despite increased genetic diversity and geographical distribution since their initial detection in 2013, H7N9 viruses have maintained a pathogenic phenotype in mammals and continue to represent an immediate threat to public health. IMPORTANCE H7N9 influenza viruses, first isolated in 2013, continue to cause human infection and represent an ongoing public health threat. Now entering the fourth wave of human infection, H7N9 viruses continue to exhibit genetic diversity in avian hosts, necessitating continuous efforts to monitor their pandemic potential. However, viruses isolated post-2013 have not been extensively studied, limiting our understanding of potential changes in virus-host adaptation. In order to ensure that current research with first-wave H7N9 viruses still pertains to more recently isolated strains, we compared the relative virulence and transmissibility of H7N9 viruses isolated during the second and third waves, through 2015, in the mouse and ferret models. Our finding that second- and third-wave viruses generally exhibit disease in mammals comparable to that of first-wave viruses strengthens our ability to extrapolate research from the 2013 viruses to current public health efforts. These data further contribute to our understanding of molecular determinants of pathogenicity, transmissibility, and tropism. JF - Journal of Virology AU - Belser, Jessica A AU - Creager, Hannah M AU - Sun, Xiangjie AU - Gustin, Kortney M AU - Jones, Tara AU - Shieh, Wun-Ju AU - Maines, Taronna R AU - Tumpey, Terrence M AD - << + $0, tft9@cdc.gov. Y1 - 2016/05// PY - 2016 DA - May 2016 SP - 4647 EP - 4657 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 90 IS - 9 SN - 0022-538X, 0022-538X KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Epithelial cells KW - Geographical distribution KW - Mammals KW - Viruses KW - Animal models KW - Genetic diversity KW - Infection KW - Public health KW - Disease transmission KW - Virulence KW - Influenza KW - pandemics KW - Mustela KW - Pathogenicity KW - Waves KW - pH effects KW - pH KW - Phylogeny KW - Data processing KW - Adaptations KW - Tropism KW - Mice KW - Adaptability KW - Lethality KW - Evolution KW - H 1000:Occupational Safety and Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1790955484?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Virology&rft.atitle=Mammalian+Pathogenesis+and+Transmission+of+H7N9+Influenza+Viruses+from+Three+Waves%2C+2013-2015&rft.au=Belser%2C+Jessica+A%3BCreager%2C+Hannah+M%3BSun%2C+Xiangjie%3BGustin%2C+Kortney+M%3BJones%2C+Tara%3BShieh%2C+Wun-Ju%3BMaines%2C+Taronna+R%3BTumpey%2C+Terrence+M&rft.aulast=Belser&rft.aufirst=Jessica&rft.date=2016-05-01&rft.volume=90&rft.issue=9&rft.spage=4647&rft.isbn=&rft.btitle=&rft.title=Journal+of+Virology&rft.issn=0022538X&rft_id=info:doi/10.1128%2FJVI.00134-16 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-05-01 N1 - Number of references - 63 N1 - Last updated - 2016-08-03 N1 - SubjectsTermNotLitGenreText - Phylogeny; Epithelial cells; Geographical distribution; Adaptations; Data processing; Tropism; Animal models; Genetic diversity; Infection; Disease transmission; Public health; Influenza; Virulence; pandemics; Lethality; Pathogenicity; Waves; pH effects; Evolution; Adaptability; Mammals; Viruses; Mice; pH; Mustela DO - http://dx.doi.org/10.1128/JVI.00134-16 ER - TY - JOUR T1 - The Relationship Between Distance to Water Source and Moderate-to-Severe Diarrhea in the Global Enterics Multi-Center Study in Kenya, 2008-2011 AN - 1790947211; PQ0003120381 AB - In the developing world, fetching water for drinking and other household uses is a substantial burden that affects water quantity and quality in the household. We used logistic regression to examine whether reported household water fetching times were a risk factor for moderate-to-severe diarrhea (MSD) using case-control data of 3,359 households from the Global Enterics Multi-Center Study in Kenya in 2009-2011. We collected additional global positioning system (GPS) data for a subset of 254 randomly selected households and compared GPS-based straight line and actual travel path distances to fetching times reported by respondents. GPS-based data were highly correlated with respondent-provided times (Spearman correlation coefficient = 0.81, P 30 minutes was reported by 25% of cases versus 15% of controls and was significantly associated with MSD where rainwater was not used in the last 2 weeks (odds ratio = 1.97, 95% confidence interval = 1.56-2.49). These data support the United Nations definition of access to an improved water source being within 30 minutes total round-trip travel time. JF - American Journal of Tropical Medicine and Hygiene AU - Nygren, Benjamin L AU - O'Reilly, Ciara E AU - Rajasingham, Anangu AU - Omore, Richard AU - Ombok, Maurice AU - Awuor, Alex O AU - Jaron, Peter AU - Moke, Fenny AU - Vulule, John AU - Laserson, Kayla AD - National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, bnygren@cdc.gov Y1 - 2016/05// PY - 2016 DA - May 2016 SP - 1143 EP - 1149 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 94 IS - 5 SN - 0002-9637, 0002-9637 KW - ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Travel KW - Data processing KW - Diarrhea KW - Positioning systems KW - Kenya KW - Depth perception KW - Households KW - Risk factors KW - International organizations KW - United Nations KW - Rain KW - Drinking water KW - Hygiene KW - Q5 08503:Characteristics, behavior and fate KW - K 03490:Miscellaneous KW - Q1 08563:Fishing gear and methods KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1790947211?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=The+Relationship+Between+Distance+to+Water+Source+and+Moderate-to-Severe+Diarrhea+in+the+Global+Enterics+Multi-Center+Study+in+Kenya%2C+2008-2011&rft.au=Nygren%2C+Benjamin+L%3BO%27Reilly%2C+Ciara+E%3BRajasingham%2C+Anangu%3BOmore%2C+Richard%3BOmbok%2C+Maurice%3BAwuor%2C+Alex+O%3BJaron%2C+Peter%3BMoke%2C+Fenny%3BVulule%2C+John%3BLaserson%2C+Kayla&rft.aulast=Nygren&rft.aufirst=Benjamin&rft.date=2016-05-01&rft.volume=94&rft.issue=5&rft.spage=1143&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.15-0393 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-05-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Positioning systems; International organizations; Hygiene; Travel; Depth perception; Diarrhea; Data processing; Risk factors; Drinking water; Households; Rain; United Nations; Kenya DO - http://dx.doi.org/10.4269/ajtmh.15-0393 ER - TY - JOUR T1 - School Start Times, Sleep, Behavioral, Health, and Academic Outcomes: A Review of the Literature AN - 1777916387 AB - BACKGROUND Insufficient sleep in adolescents has been shown to be associated with a wide variety of adverse outcomes, from poor mental and physical health to behavioral problems and lower academic grades. However, most high school students do not get sufficient sleep. Delaying school start times for adolescents has been proposed as a policy change to address insufficient sleep in this population and potentially to improve students' academic performance, reduce engagement in risk behaviors, and improve health. METHODS This article reviews 38 reports examining the association between school start times, sleep, and other outcomes among adolescent students. RESULTS Most studies reviewed provide evidence that delaying school start time increases weeknight sleep duration among adolescents, primarily by delaying rise times. Most of the studies saw a significant increase in sleep duration even with relatively small delays in start times of half an hour or so. Later start times also generally correspond to improved attendance, less tardiness, less falling asleep in class, better grades, and fewer motor vehicle crashes. CONCLUSIONS Although additional research is necessary, research results that are already available should be disseminated to stakeholders to enable the development of evidence-based school policies. JF - The Journal of School Health AU - Wheaton, Anne G AU - Chapman, Daniel P AU - Croft, Janet B AD - Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Hwy. NE, Mailstop F-78, Atlanta, GA ; Epidemiology and Surveillance Branch, Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Hwy. NE Mailstop F-78, Atlanta, GA Y1 - 2016/05// PY - 2016 DA - May 2016 SP - 363 EP - 381 CY - Kent PB - Wiley Subscription Services, Inc. VL - 86 IS - 5 SN - 0022-4391 KW - Physical Fitness And Hygiene KW - Sleep KW - Academic achievement KW - Adolescents KW - Behavioural problems KW - Evidence based KW - Health behaviour KW - Health status KW - Literature reviews KW - Mental health KW - Policy making KW - Risk behaviour KW - Risk reduction KW - Stakeholders KW - Teenagers KW - Students KW - Behavior UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1777916387?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+School+Health&rft.atitle=School+Start+Times%2C+Sleep%2C+Behavioral%2C+Health%2C+and+Academic+Outcomes%3A+A+Review+of+the+Literature&rft.au=Wheaton%2C+Anne+G%3BChapman%2C+Daniel+P%3BCroft%2C+Janet+B&rft.aulast=Wheaton&rft.aufirst=Anne&rft.date=2016-05-01&rft.volume=86&rft.issue=5&rft.spage=363&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+School+Health&rft.issn=00224391&rft_id=info:doi/10.1111%2Fjosh.12388 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Copyright - © 2016, American School Health Association N1 - Last updated - 2016-10-05 DO - http://dx.doi.org/10.1111/josh.12388 ER - TY - JOUR T1 - Measles Virus Neutralizing Antibody Response, Cell-Mediated Immunity, and Immunoglobulin G Antibody Avidity Before and After Receipt of a Third Dose of Measles, Mumps, and Rubella Vaccine in Young Adults AN - 1808729877; PQ0003170887 AB - Background.Two doses of measles, mumps, and rubella (MMR) vaccine are 97% effective against measles, but waning antibody immunity to measles and failure of the 2-dose vaccine occur. We administered a third MMR dose (MMR3) to young adults and assessed immunogenicity over 1 year. Methods.Measles virus (MeV) neutralizing antibody concentrations, cell-mediated immunity (CMI), and immunoglobulin G (IgG) antibody avidity were assessed at baseline and 1 month and 1 year after MMR3 receipt. Results.Of 662 subjects at baseline, 1 (0.2%) was seronegative for MeV-neutralizing antibodies (level, or =4-fold rise in neutralizing antibodies. One year after MMR3 receipt, no subject was seronegative, and 10 of 617 (1.6%) had low neutralizing antibody levels. CMI analyses showed low levels of spot-forming cells after stimulation, suggesting the presence of T-cell memory, but the response was minimal after MMR3 receipt. MeV IgG avidity did not correlate with findings of neutralization analyses. Conclusions.Most subjects were seropositive before MMR3 receipt, and very few had a secondary immune response after MMR3 receipt. Similarly, CMI and avidity analyses showed minimal qualitative improvements in immune response after MMR3 receipt. We did not find compelling data to support a routine third dose of MMR vaccine. JF - Journal of Infectious Diseases AU - Fiebelkorn, Amy Parker AU - Coleman, Laura A AU - Belongia, Edward A AU - Freeman, Sandra K AU - York, Daphne AU - Bi, Daoling AU - Kulkarni, Ashwin AU - Audet, Susette AU - Mercader, Sara AU - McGrew, Marcia AU - Hickman, Carole J AU - Bellini, William J AU - Shivakoti, Rupak AU - Griffin, Diane E AU - Beeler, Judith AD - National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, afiebelkorn@cdc.gov Y1 - 2016/04/01/ PY - 2016 DA - 2016 Apr 01 SP - 1115 EP - 1123 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 213 IS - 7 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Immunology Abstracts; Health & Safety Science Abstracts KW - measles KW - third dose of measles, mumps, rubella (MMR) vaccine KW - measles vaccine immunogenicity KW - vaccine-preventable disease KW - immunization KW - cell-mediated immunity KW - measles virus antibody avidity KW - Data processing KW - Measles KW - Immunological memory KW - Antibody response KW - Measles virus KW - Rubella KW - Infectious diseases KW - Immunity (cell-mediated) KW - Immunogenicity KW - Avidity KW - Lymphocytes T KW - Immunoglobulin G KW - Young adults KW - Immune response KW - Vaccines KW - Neutralization KW - Mumps KW - V 22350:Immunology KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808729877?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Measles+Virus+Neutralizing+Antibody+Response%2C+Cell-Mediated+Immunity%2C+and+Immunoglobulin+G+Antibody+Avidity+Before+and+After+Receipt+of+a+Third+Dose+of+Measles%2C+Mumps%2C+and+Rubella+Vaccine+in+Young+Adults&rft.au=Fiebelkorn%2C+Amy+Parker%3BColeman%2C+Laura+A%3BBelongia%2C+Edward+A%3BFreeman%2C+Sandra+K%3BYork%2C+Daphne%3BBi%2C+Daoling%3BKulkarni%2C+Ashwin%3BAudet%2C+Susette%3BMercader%2C+Sara%3BMcGrew%2C+Marcia%3BHickman%2C+Carole+J%3BBellini%2C+William+J%3BShivakoti%2C+Rupak%3BGriffin%2C+Diane+E%3BBeeler%2C+Judith&rft.aulast=Fiebelkorn&rft.aufirst=Amy&rft.date=2016-04-01&rft.volume=213&rft.issue=7&rft.spage=1115&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiv555 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-08-04 N1 - SubjectsTermNotLitGenreText - Data processing; Measles; Immunological memory; Antibody response; Rubella; Immunity (cell-mediated); Avidity; Immunogenicity; Immunoglobulin G; Lymphocytes T; Vaccines; Immune response; Mumps; Infectious diseases; Young adults; Neutralization; Measles virus DO - http://dx.doi.org/10.1093/infdis/jiv555 ER - TY - JOUR T1 - Enhanced surveillance of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccines in pregnancy in the Vaccine Adverse Event Reporting System (VAERS), 2011-2015 AN - 1787985767; PQ0002951534 AB - Background In October 2011, the Advisory Committee on Immunization Practices (ACIP) issued updated recommendations that all pregnant women routinely receive a dose of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine. Objectives We characterized reports to the Vaccine Adverse Event Reporting System (VAERS) in pregnant women who received Tdap after this updated recommendation (2011-2015) and compared the pattern of adverse events (AEs) with the period before the updated recommendation (2005-2010). Methods We searched the VAERS database for reports of AEs in pregnant women who received Tdap vaccine after the routine recommendation (11/01/2011-6/30/2015) and compared it to published data before the routine Tdap recommendation (01/01/2005-06/30/2010). We conducted clinical review of reports and available medical records. The clinical pattern of reports in the post-recommendation period was compared with the pattern before the routine Tdap recommendation. Results We found 392 reports of Tdap vaccination after the routine recommendation. One neonatal death but no maternal deaths were reported. No maternal or neonatal deaths were reported before the recommendation. We observed an increase in proportion of reports for stillbirths (1.5-2.8%) and injection site reactions/arm pain (4.5-11.9%) after the recommendation compared to the period before the routine recommendation for Tdap during pregnancy. We noted a decrease in reports of spontaneous abortion (16.7-1%). After the 2011 Tdap recommendation, in most reports, vaccination (79%) occurred during the third trimester compared to 4% before the 2011 Tdap recommendation. Twenty-six reports of repeat Tdap were received in VAERS; 13 did not report an AE. One medical facility accounted for 27% of all submitted reports. Conclusions No new or unexpected vaccine AEs were noted among pregnant women who received Tdap after routine recommendations for maternal Tdap vaccination. Changes in reporting patterns would be expected, given the broader use of Tdap in pregnant women in the third trimester. JF - Vaccine AU - Moro, Pedro L AU - Cragan, Janet AU - Tepper, Naomi AU - Zheteyeva, Yenlik AU - Museru, Oidda AU - Lewis, Paige AU - Broder, Karen AD - Immunization Safety Office, Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), Centers for Disease Control and Prevention (CDC), 1600 Clifton Road, MS D26, Atlanta, GA 30333, USA Y1 - 2016/04// PY - 2016 DA - April 2016 SP - 2349 EP - 2353 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 34 IS - 20 SN - 0264-410X, 0264-410X KW - Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts; Immunology Abstracts KW - Adverse events KW - Epidemiology KW - Tdap KW - Pregnancy KW - Surveillance KW - Vaccine safety KW - Pertussis KW - Abortion KW - Pain KW - Toxoids KW - Tetanus KW - Mortality KW - Data processing KW - medical records KW - Advisory committees KW - Diphtheria KW - Vaccination KW - Immunization KW - Databases KW - Reviews KW - Neonates KW - Vaccines KW - Side effects KW - F 06905:Vaccines KW - J 02350:Immunology KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1787985767?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Enhanced+surveillance+of+tetanus+toxoid%2C+reduced+diphtheria+toxoid%2C+and+acellular+pertussis+%28Tdap%29+vaccines+in+pregnancy+in+the+Vaccine+Adverse+Event+Reporting+System+%28VAERS%29%2C+2011-2015&rft.au=Moro%2C+Pedro+L%3BCragan%2C+Janet%3BTepper%2C+Naomi%3BZheteyeva%2C+Yenlik%3BMuseru%2C+Oidda%3BLewis%2C+Paige%3BBroder%2C+Karen&rft.aulast=Moro&rft.aufirst=Pedro&rft.date=2016-04-01&rft.volume=34&rft.issue=20&rft.spage=2349&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/10.1016%2Fj.vaccine.2016.03.049 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-05-01 N1 - Number of references - 16 N1 - Last updated - 2016-07-07 N1 - SubjectsTermNotLitGenreText - Pertussis; Data processing; medical records; Abortion; Pain; Toxoids; Diphtheria; Tetanus; Vaccination; Pregnancy; Databases; Reviews; Vaccines; Neonates; Mortality; Advisory committees; Immunization; Side effects DO - http://dx.doi.org/10.1016/j.vaccine.2016.03.049 ER - TY - JOUR T1 - Preventive malaria treatment for contacts of patients with Ebola virus disease in the context of the west Africa 2014-15 Ebola virus disease response: an economic analysis AN - 1785231345; PQ0002849097 AB - Background After the detection of an Ebola virus disease outbreak in west Africa in 2014, one of the elements of the response was to contact trace and isolate patients in specialised Ebola treatment units (ETUs) at onset of fever. We aimed to assess the economic feasibility of administering preventive malaria treatment to all contacts of patients with Ebola virus disease, to prevent the onset of febrile malaria and subsequent admission to ETUs. Methods We used a decision tree model to analyse the costs of preventive malaria treatment (artemisinin-based combination treatment [ACT]) for all contacts of patients with Ebola virus disease (in terms of administration and averted ETU-stay costs) and benefits (in terms of averted ETU admissions) in west Africa, from a health-care provider perspective. The period of analyses was 1 year, which is roughly similar to the duration of the 2014-15 west Africa Ebola outbreak response. We calculated the intervention's cost per ETU admission averted (average cost-effectiveness ratio) by season (wet and dry), country (Liberia, Sierra Leone, and Guinea), and age of contact (<5 years, 5-14 years, and greater than or equal to 15 years). We did sensitivity analyses to assess how results varied with malaria parasite prevalence (in children aged 2-10 years), daily cost of ETU stay (for Liberian malaria incidence levels), and compliance and effectiveness of preventive malaria treatment. Findings Administration of ACTs to contacts of patients with Ebola virus disease was cost saving for contacts of all ages in Liberia, Sierra Leone, and Guinea, in both seasons, from a health-care provider perspective. In the wet season, preventive malaria treatment was estimated to reduce the probability of a contact being admitted to an ETU by a maximum of 36% (in Guinea, for contacts aged <5 years), and a minimum of 10% (in Guinea and Sierra Leone, for those aged greater than or equal to 15 years). Assuming 85% compliance and taking into account the African population pyramid, the intervention is expected to be cost saving in contacts of all age groups in areas with malaria parasite prevalence in children aged 2-10 years as low as 10%. In Liberia during the wet season, malaria preventive treatment was cost saving even when average daily bed-stay costs were as low as US$5 for children younger than 5 years, $9 for those aged 5-14 years, and $22 for those aged 15 years or older. Interpretation Administration of preventive malaria treatment to contacts of patients with Ebola virus disease should be considered by public health officials when addressing Ebola virus disease outbreaks in countries and seasons where malaria reaches high levels of transmission. Funding Centers for Disease Control and Prevention. JF - Lancet Infectious Diseases AU - Carias, Cristina AU - Greening, Bradford Jr AU - Campbell, Caresse G AU - Meltzer, Martin I AU - Hamel, Mary J AD - National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA Y1 - 2016/04// PY - 2016 DA - April 2016 SP - 449 EP - 458 PB - Elsevier B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 16 IS - 4 SN - 1473-3099, 1473-3099 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Virology & AIDS Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Parasites KW - Age KW - Human diseases KW - Disease control KW - Ebola virus KW - Malaria KW - Models KW - Public health KW - Disease transmission KW - Liberia KW - Fever KW - Economic feasibility KW - Rainy season KW - Guinea KW - Economics KW - Sierra Leone KW - Age determination KW - Children KW - Africa KW - K 03400:Human Diseases KW - Q1 08604:Stock assessment and management KW - Q5 08524:Public health, medicines, dangerous organisms KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1785231345?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Changes+in+Knowledge+of+Bat+Rabies+and+Human+Exposure+among+United+States+Cavers&rft.au=Mehal%2C+Jason+M%3BHolman%2C+Robert+C%3BBrass%2C+Danny+A%3BBlanton%2C+Jesse+D%3BPetersen%2C+Brett+W&rft.aulast=Mehal&rft.aufirst=Jason&rft.date=2014-02-01&rft.volume=90&rft.issue=2&rft.spage=263&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.13-0502 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-04-01 N1 - Number of references - 27 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Parasites; Economic feasibility; Human diseases; Rainy season; Disease control; Malaria; Age determination; Disease transmission; Public health; Fever; Age; Economics; Children; Models; Ebola virus; Liberia; Guinea; Africa; Sierra Leone DO - http://dx.doi.org/10.1016/S1473-3099(15)00465-X ER - TY - JOUR T1 - Use and effectiveness of quitlines versus Web-based tobacco cessation interventions among 4 state tobacco control programs AN - 1780526200; PQ0002846731 AB - BACKGROUND Comparative effectiveness studies of state tobacco quitlines and Web-based tobacco cessation interventions are limited. In 2009, the US Centers for Disease Control and Prevention undertook a study of the comparative effectiveness of state quitlines and Web-based tobacco cessation interventions. METHODS Standardized questionnaires were administered to smokers who enrolled exclusively in either quitlines or Web-based tobacco cessation services in 4 states in 2011-2012. The primary outcome was the 30-day point prevalence abstinence (PPA) rate at 7 months both between and within interventions. RESULTS A total of 4086 participants were included in the analysis. Quitline users were significantly older, more heterogeneous in terms of race and ethnicity, less educated, less likely to be employed, and more often single than Web-based users. The 7-month 30-day PPA rate was 32% for quitline users and 27% for Web-based users. Multivariate models comparing 30-day PPA rates between interventions indicated that significantly increased odds of quitting were associated with being partnered, not living with another smoker, low baseline cigarette use, and more interactions with the intervention. After adjustments for demographic and tobacco use characteristics, quitline users had 1.26 the odds of being abstinent in comparison with Web-based users (95% confidence interval, 1.00-1.58; P = .053). CONCLUSIONS This is one of the largest comparative effectiveness studies of state tobacco cessation interventions to date. These findings will help public health agencies develop and tailor evidence-based tobacco cessation programs. Further research should focus on users of Web-based cessation interventions sponsored by state health departments and their cost-effectiveness. Cancer 2016; 122:1126-1133. Published 2016. This article is a U.S. Government work and is in the public domain in the USA. Limited information exists for comparing state quitlines and Web-based tobacco cessation interventions. Exclusive users of quitlines and Web-based interventions are different with respect to demographics and tobacco use. The intervention type approaches but does not meet statistical significance as a factor associated with 30-day abstinence measured at 7 months' follow-up in a model adjusted for demographics and tobacco use. JF - Cancer AU - Neri, Antonio J AU - Momin, Behnoosh R AU - Thompson, Trevor D AU - Kahende, Jennifer AU - Zhang, Lei AU - Puckett, Mary C AU - Stewart, Sherri L AD - Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia. Y1 - 2016/04// PY - 2016 DA - April 2016 SP - 1126 EP - 1133 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 122 IS - 7 SN - 0008-543X, 0008-543X KW - Toxicology Abstracts KW - Inventories KW - Statistics KW - Cigarettes KW - Control programs KW - Disease control KW - Statistical analysis KW - Cancer KW - Public health KW - Models KW - Demography KW - Tobacco KW - Races KW - Ethnic groups KW - X 24380:Social Poisons & Drug Abuse UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1780526200?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cancer&rft.atitle=Use+and+effectiveness+of+quitlines+versus+Web-based+tobacco+cessation+interventions+among+4+state+tobacco+control+programs&rft.au=Neri%2C+Antonio+J%3BMomin%2C+Behnoosh+R%3BThompson%2C+Trevor+D%3BKahende%2C+Jennifer%3BZhang%2C+Lei%3BPuckett%2C+Mary+C%3BStewart%2C+Sherri+L&rft.aulast=Neri&rft.aufirst=Antonio&rft.date=2016-04-01&rft.volume=77&rft.issue=5&rft.spage=1728&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-04-01 N1 - Last updated - 2016-05-13 N1 - SubjectsTermNotLitGenreText - Inventories; Statistics; Cigarettes; Control programs; Statistical analysis; Disease control; Cancer; Models; Public health; Demography; Tobacco; Ethnic groups; Races DO - http://dx.doi.org/10.1002/cncr.29739 ER - TY - JOUR T1 - Impact and cost-effectiveness of a second tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine dose to prevent pertussis in the United States AN - 1776670629; PQ0002810163 AB - Introduction The United States experienced a substantial increase in reported pertussis cases over the last decade. Since 2005, persons 11 years and older have been routinely recommended to receive a single dose of tetanus toxoid, reduced diphtheria toxoid and acellular pertussis (Tdap) vaccine. The objective of this analysis was to evaluate the potential impact and cost-effectiveness of recommending a second dose of Tdap. Methods A static cohort model was used to calculate the epidemiologic and economic impact of adding a second dose of Tdap at age 16 or 21 years. Projected costs and outcomes were examined from a societal perspective over a 20-year period. Quality-adjusted Life Years (QALY) saved were calculated. Results Using baseline pertussis incidence from the National Notifiable Diseases Surveillance System, Tdap revaccination at either age 16 or 21 years would reduce outpatient visits by 433 (5%) and 285 (4%), and hospitalization cases by 7 (7%) and 5 (5%), respectively. The costs per QALY saved with a second dose of Tdap were approximately US $19.7 million (16 years) and $26.2 million (21 years). In sensitivity analyses, incidence most influenced the model; as incidence increased, the costs per QALY decreased. To a lesser degree, initial vaccine effectiveness and waning of effectiveness also affected cost outcomes. Multivariate sensitivity analyses showed that under a set of optimistic assumptions, the cost per QALY saved would be approximately $163,361 (16 years) and $204,556 (21 years). Conclusion A second dose of Tdap resulted in a slight decrease in the number of cases and other outcomes, and that trend is more apparent when revaccinating at age 16 years than at age 21 years. Both revaccination strategies had high dollar per QALY saved even under optimistic assumptions in a multivariate sensitivity analysis. JF - Vaccine AU - Kamiya, Hajime AU - Cho, Bo-Hyun AU - Messonnier, Mark L AU - Clark, Thomas A AU - Liang, Jennifer L AD - Epidemic Intelligence Service, Division of Scientific Education and Professional Development, Center for Surveillance, Epidemiology and Laboratory Services, Centers for Disease Control and Prevention, 1600 Clifton Rd, N.E., Atlanta, GA 30329-4027, United States Y1 - 2016/04// PY - 2016 DA - April 2016 SP - 1832 EP - 1838 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 34 IS - 15 SN - 0264-410X, 0264-410X KW - Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts; Immunology Abstracts KW - Pertussis KW - Cost-effectiveness KW - Tdap KW - Revaccination KW - Adolescent KW - Adult KW - Age KW - Toxoids KW - Diphtheria KW - Tetanus KW - Cost benefit analysis KW - Models KW - USA KW - Sensitivity analysis KW - Economics KW - Vaccines KW - J 02400:Human Diseases KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1776670629?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Impact+and+cost-effectiveness+of+a+second+tetanus+toxoid%2C+reduced+diphtheria+toxoid%2C+and+acellular+pertussis+%28Tdap%29+vaccine+dose+to+prevent+pertussis+in+the+United+States&rft.au=Kamiya%2C+Hajime%3BCho%2C+Bo-Hyun%3BMessonnier%2C+Mark+L%3BClark%2C+Thomas+A%3BLiang%2C+Jennifer+L&rft.aulast=Kamiya&rft.aufirst=Hajime&rft.date=2016-04-01&rft.volume=34&rft.issue=15&rft.spage=1832&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/10.1016%2Fj.vaccine.2016.02.027 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-03-01 N1 - Number of references - 23 N1 - Last updated - 2016-05-13 N1 - SubjectsTermNotLitGenreText - Pertussis; Age; Economics; Diphtheria; Toxoids; Vaccines; Tetanus; Models; Sensitivity analysis; Cost benefit analysis; USA DO - http://dx.doi.org/10.1016/j.vaccine.2016.02.027 ER - TY - JOUR T1 - Beliefs, Behaviors, and Perceptions of Community-Led Total Sanitation and Their Relation to Improved Sanitation in Rural Zambia AN - 1787968999; PQ0002948309 AB - Inadequate hygiene and sanitation remain leading global contributors to morbidity and mortality in children and adults. One strategy for improving sanitation access is community-led total sanitation (CLTS), in which participants are guided into self-realization of the importance of sanitation through activities called "triggering." This qualitative study explored community members' and stakeholders' sanitation, knowledge, perceptions, and behaviors during early CLTS implementation in Zambia. We conducted 67 in-depth interviews and 24 focus group discussions in six districts in Zambia 12-18 months after CLTS implementation. Triggering activities elicited strong emotions, including shame, disgust, and peer pressure, which persuaded individuals and families to build and use latrines and handwashing stations. New sanitation behaviors were also encouraged by the hierarchical influences of traditional leaders and sanitation action groups and by children's opinions. Poor soil conditions were identified as barriers to latrine construction. Taboos, including prohibition of different generations of family members, in-laws, and opposite genders from using the same toilet, were barriers for using sanitation facilities. CLTS, through community empowerment and ownership, produced powerful responses that encouraged construction and use of latrines and handwashing practices. These qualitative data suggest that CLTS is effective for improving sanitation beliefs and behaviors in Zambia. JF - American Journal of Tropical Medicine and Hygiene AU - Lawrence, J Joseph AU - Yeboah-Antwi, Kojo AU - Biemba, Godfrey AU - Ram, Pavani K AU - Osbert, Nicolas AU - Sabin, Lora L AU - Hamer, Davidson H AD - Zambia Center for Applied Health Research and Development, Lusaka, Zambia, ymq1@cdc.gov Y1 - 2016/03// PY - 2016 DA - March 2016 SP - 553 EP - 562 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 94 IS - 3 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts KW - Stakeholders KW - Emotions KW - Barriers KW - Morbidity KW - Soil KW - Sanitation KW - Soils KW - Empowerment KW - Pressure KW - Sex KW - Mortality KW - Data processing KW - Toilets KW - Children KW - Zambia KW - Behavior KW - Perception KW - Gender KW - Property rights KW - Hygiene KW - Mortality causes KW - Rural areas KW - K 03400:Human Diseases KW - Q1 08442:Population dynamics KW - Q5 08504:Effects on organisms KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1787968999?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Beliefs%2C+Behaviors%2C+and+Perceptions+of+Community-Led+Total+Sanitation+and+Their+Relation+to+Improved+Sanitation+in+Rural+Zambia&rft.au=Lawrence%2C+J+Joseph%3BYeboah-Antwi%2C+Kojo%3BBiemba%2C+Godfrey%3BRam%2C+Pavani+K%3BOsbert%2C+Nicolas%3BSabin%2C+Lora+L%3BHamer%2C+Davidson+H&rft.aulast=Lawrence&rft.aufirst=J&rft.date=2016-03-01&rft.volume=94&rft.issue=3&rft.spage=553&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.15-0335 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-05-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Barriers; Soils; Property rights; Hygiene; Mortality causes; Sex; Soil; Mortality; Emotions; Data processing; Sanitation; Toilets; Perception; Pressure; Children; Morbidity; Stakeholders; Behavior; Gender; Empowerment; Rural areas; Zambia DO - http://dx.doi.org/10.4269/ajtmh.15-0335 ER - TY - JOUR T1 - Humanized Mouse Model of Ebola Virus Disease Mimics the Immune Responses in Human Disease AN - 1780499309; PQ0002893205 AB - Animal models recapitulating human Ebola virus disease (EVD) are critical for insights into virus pathogenesis. Ebola virus (EBOV) isolates derived directly from human specimens do not, without adaptation, cause disease in immunocompetent adult rodents. Here, we describe EVD in mice engrafted with human immune cells (hu-BLT). hu-BLT mice developed EVD following wild-type EBOV infection. Infection with high-dose EBOV resulted in rapid, lethal EVD with high viral loads, alterations in key human antiviral immune cytokines and chemokines, and severe histopathologic findings similar to those shown in the limited human postmortem data available. A dose- and donor-dependent clinical course was observed in hu-BLT mice infected with lower doses of either Mayinga (1976) or Makona (2014) isolates derived from human EBOV cases. Engraftment of the human cellular immune system appeared to be essential for the observed virulence, as nonengrafted mice did not support productive EBOV replication or develop lethal disease. hu-BLT mice offer a unique model for investigating the human immune response in EVD and an alternative animal model for EVD pathogenesis studies and therapeutic screening. JF - Journal of Infectious Diseases AU - Bird, Brian H AU - Spengler, Jessica R AU - Chakrabarti, Ayan K AU - Khristova, Marina L AU - Sealy, Tara K AU - Coleman-Mccray, Joann D AU - Martin, Brock E AU - Dodd, Kimberly A AU - Goldsmith, Cynthia S AU - Sanders, Jeanine AU - Zaki, Sherif R AU - Nichol, Stuart T AU - Spiropoulou, Christina F AD - Viral Special Pathogens Branch, ccs8@cdc.gov Y1 - 2016/03/01/ PY - 2016 DA - 2016 Mar 01 SP - 703 EP - 711 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 213 IS - 5 SN - 0022-1899, 0022-1899 KW - Immunology Abstracts; Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Ebola virus disease KW - animal model KW - viral hemorrhagic fever KW - humanized mice KW - cytokine profile KW - virus pathogenesis KW - Chemokines KW - Data processing KW - Adaptations KW - Replication KW - Immune system KW - Viruses KW - Animal models KW - Ebola virus KW - Mice KW - Infection KW - Virulence KW - Adaptability KW - Infectious diseases KW - Cytokines KW - Immune response KW - Rodents KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - V 22350:Immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1780499309?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Humanized+Mouse+Model+of+Ebola+Virus+Disease+Mimics+the+Immune+Responses+in+Human+Disease&rft.au=Bird%2C+Brian+H%3BSpengler%2C+Jessica+R%3BChakrabarti%2C+Ayan+K%3BKhristova%2C+Marina+L%3BSealy%2C+Tara+K%3BColeman-Mccray%2C+Joann+D%3BMartin%2C+Brock+E%3BDodd%2C+Kimberly+A%3BGoldsmith%2C+Cynthia+S%3BSanders%2C+Jeanine%3BZaki%2C+Sherif+R%3BNichol%2C+Stuart+T%3BSpiropoulou%2C+Christina+F&rft.aulast=Bird&rft.aufirst=Brian&rft.date=2016-03-01&rft.volume=213&rft.issue=5&rft.spage=703&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiv538 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-04-01 N1 - Last updated - 2016-08-03 N1 - SubjectsTermNotLitGenreText - Virulence; Chemokines; Adaptations; Data processing; Replication; Animal models; Cytokines; Immune response; Infection; Adaptability; Infectious diseases; Immune system; Viruses; Mice; Rodents; Ebola virus DO - http://dx.doi.org/10.1093/infdis/jiv538 ER - TY - JOUR T1 - HPV vaccination coverage of teen girls: The influence of health care providers AN - 1773849347; PQ0002717350 AB - Background Between 2010 and 2014, the percentage of 13-17 year-old girls administered greater than or equal to 3 doses of the human papilloma virus (HPV) vaccine ("fully vaccinated") increased by 7.7 percentage points to 39.7%, and the percentage not administered any doses of the HPV vaccine ("not immunized") decreased by 11.3 percentage points to 40.0%. Objective To evaluate the complex interactions between parents' vaccine-related beliefs, demographic factors, and HPV immunization status. Methods Vaccine-related parental beliefs and sociodemographic data collected by the 2010 National Immunization Survey-Teen among teen girls (n=8490) were analyzed. HPV vaccination status was determined from teens' health care provider (HCP) records. Results Among teen girls either unvaccinated or fully vaccinated against HPV, teen girls whose parent was positively influenced to vaccinate their teen daughter against HPV were 48.2 percentage points more likely to be fully vaccinated. Parents who reported being positively influenced to vaccinate against HPV were 28.9 percentage points more likely to report that their daughter's HCP talked about the HPV vaccine, 27.2 percentage points more likely to report that their daughter's HCP gave enough time to discuss the HPV shot, and 43.4 percentage points more likely to report that their daughter's HCP recommended the HPV vaccine (p<0.05). Among teen girls administered 1-2 doses of the HPV vaccine, 87.0% had missed opportunities for HPV vaccine administration. Conclusion Results suggest that an important pathway to achieving higher greater than or equal to 3 dose HPV vaccine coverage is by increasing HPV vaccination series initiation though HCP talking to parents about the HPV vaccine, giving parents time to discuss the vaccine, and by making a strong recommendation for the HPV. Also, HPV vaccination series completion rates may be increased by eliminating missed opportunities to vaccinate against HPV and scheduling additional follow-up visits to administer missing HPV vaccine doses. JF - Vaccine AU - Smith, Philip J AU - Stokley, Shannon AU - Bednarczyk, Robert A AU - Orenstein, Walter A AU - Omer, Saad B AD - Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases, Immunization Services Division, MS A-19, 1600 Clifton Road, NE, Atlanta, GA 30333, United States Y1 - 2016/03// PY - 2016 DA - March 2016 SP - 1604 EP - 1610 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 34 IS - 13 SN - 0264-410X, 0264-410X KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts; Immunology Abstracts KW - HPV KW - Parental concerns KW - Provider influence KW - Attributable risk KW - Demography KW - Data processing KW - Health care KW - Vaccines KW - Vaccination KW - Immunization KW - Human papillomavirus KW - V 22350:Immunology KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1773849347?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=HPV+vaccination+coverage+of+teen+girls%3A+The+influence+of+health+care+providers&rft.au=Smith%2C+Philip+J%3BStokley%2C+Shannon%3BBednarczyk%2C+Robert+A%3BOrenstein%2C+Walter+A%3BOmer%2C+Saad+B&rft.aulast=Smith&rft.aufirst=Philip&rft.date=2016-03-01&rft.volume=34&rft.issue=13&rft.spage=1604&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/10.1016%2Fj.vaccine.2016.01.061 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-03-01 N1 - Number of references - 48 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Demography; Data processing; Vaccines; Vaccination; Health care; Immunization; Human papillomavirus DO - http://dx.doi.org/10.1016/j.vaccine.2016.01.061 ER - TY - JOUR T1 - A simple procedure for estimating pseudo risk ratios from exposure to non-carcinogenic chemical mixtures. AN - 1765922383; 25667015 AB - Non-cancer risk assessment traditionally assumes a threshold of effect, below which there is a negligible risk of an adverse effect. The Agency for Toxic Substances and Disease Registry derives health-based guidance values known as Minimal Risk Levels (MRLs) as estimates of the toxicity threshold for non-carcinogens. Although the definition of an MRL, as well as EPA reference dose values (RfD and RfC), is a level that corresponds to "negligible risk," they represent daily exposure doses or concentrations, not risks. We present a new approach to calculate the risk at exposure to specific doses for chemical mixtures, the assumption in this approach is to assign de minimis risk at the MRL. The assigned risk enables the estimation of parameters in an exponential model, providing a complete dose-response curve for each compound from the chosen point of departure to zero. We estimated parameters for 27 chemicals. The value of k, which determines the shape of the dose-response curve, was moderately insensitive to the choice of the risk at the MRL. The approach presented here allows for the calculation of a risk from a single substance or the combined risk from multiple chemical exposures in a community. The methodology is applicable from point of departure data derived from quantal data, such as data from benchmark dose analyses or from data that can be transformed into probabilities, such as lowest-observed-adverse-effect level. The individual risks are used to calculate risk ratios that can facilitate comparison and cost-benefit analyses of environmental contamination control strategies. JF - Archives of toxicology AU - Scinicariello, Franco AU - Portier, Christopher AD - National Center for Environmental Health/Agency for Toxic Substances and Disease Registry, Centers for Disease Control and Prevention, 4770 Buford Hwy, MS F57, Atlanta, GA, 30341, USA. fes6@cdc.gov. ; National Center for Environmental Health/Agency for Toxic Substances and Disease Registry, Centers for Disease Control and Prevention, 4770 Buford Hwy, MS F57, Atlanta, GA, 30341, USA. cportier@mac.com. Y1 - 2016/03// PY - 2016 DA - March 2016 SP - 513 EP - 523 VL - 90 IS - 3 KW - Carcinogens KW - 0 KW - Complex Mixtures KW - Index Medicus KW - Risk assessment KW - Acceptable risk KW - Lowest-observed-adverse effect KW - Point of departure KW - Toxicological mixtures KW - Benchmark dose KW - Minimal Risk Levels KW - Probability KW - Reference Values KW - Humans KW - Carcinogens -- toxicity KW - Benchmarking KW - Models, Theoretical KW - Risk Assessment -- methods KW - Complex Mixtures -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1765922383?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Archives+of+toxicology&rft.atitle=A+simple+procedure+for+estimating+pseudo+risk+ratios+from+exposure+to+non-carcinogenic+chemical+mixtures.&rft.au=Scinicariello%2C+Franco%3BPortier%2C+Christopher&rft.aulast=Scinicariello&rft.aufirst=Franco&rft.date=2016-03-01&rft.volume=90&rft.issue=3&rft.spage=513&rft.isbn=&rft.btitle=&rft.title=Archives+of+toxicology&rft.issn=1432-0738&rft_id=info:doi/10.1007%2Fs00204-015-1467-z LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2016-11-14 N1 - Date created - 2016-02-16 N1 - Date revised - 2017-01-14 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1007/s00204-015-1467-z ER - TY - JOUR T1 - Assessing arsenic exposure in households using bottled water or point-of-use treatment systems to mitigate well water contamination. AN - 1764342257; 26674699 AB - There is little published literature on the efficacy of strategies to reduce exposure to residential well water arsenic. The objectives of our study were to: 1) determine if water arsenic remained a significant exposure source in households using bottled water or point-of-use treatment systems; and 2) evaluate the major sources and routes of any remaining arsenic exposure. We conducted a cross-sectional study of 167 households in Maine using one of these two strategies to prevent exposure to arsenic. Most households included one adult and at least one child. Untreated well water arsenic concentrations ranged from <10 μg/L to 640 μg/L. Urine samples, water samples, daily diet and bathing diaries, and household dietary and water use habit surveys were collected. Generalized estimating equations were used to model the relationship between urinary arsenic and untreated well water arsenic concentration, while accounting for documented consumption of untreated water and dietary sources. If mitigation strategies were fully effective, there should be no relationship between urinary arsenic and well water arsenic. To the contrary, we found that untreated arsenic water concentration remained a significant (p ≤ 0.001) predictor of urinary arsenic levels. When untreated water arsenic concentrations were <40 μg/L, untreated water arsenic was no longer a significant predictor of urinary arsenic. Time spent bathing (alone or in combination with water arsenic concentration) was not associated with urinary arsenic. A predictive analysis of the average study participant suggested that when untreated water arsenic ranged from 100 to 500 μg/L, elimination of any untreated water use would result in an 8%-32% reduction in urinary arsenic for young children, and a 14%-59% reduction for adults. These results demonstrate the importance of complying with a point-of-use or bottled water exposure reduction strategy. However, there remained unexplained, water-related routes of exposure. Copyright © 2015 Elsevier B.V. All rights reserved. JF - The Science of the total environment AU - Smith, Andrew E AU - Lincoln, Rebecca A AU - Paulu, Chris AU - Simones, Thomas L AU - Caldwell, Kathleen L AU - Jones, Robert L AU - Backer, Lorraine C AD - Maine Department of Health and Human Services, Maine Center for Disease Control and Prevention, 286 Water Street, Augusta, ME 04333, USA. Electronic address: Andy.E.Smith@maine.gov. ; Maine Department of Health and Human Services, Maine Center for Disease Control and Prevention, 286 Water Street, Augusta, ME 04333, USA. ; Maine Department of Health and Human Services, Maine Center for Disease Control and Prevention, 286 Water Street, Augusta, ME 04333, USA; University of Southern Maine, Muskie School of Public Service, PO Box 9300, Portland, ME 04104-9300, USA. ; Centers for Disease Control and Prevention, National Center for Environmental Health, Inorganic and Radiation Analytical Toxicology Branch, 4770 Buford Highway NE, MS F-18, Chamblee, GA 30341, USA. ; Centers for Disease Control and Prevention, National Center for Environmental Health, Health Studies Branch, 4770 Buford Highway NE, MS F-60, Chamblee, GA 30341, USA. Y1 - 2016/02/15/ PY - 2016 DA - 2016 Feb 15 SP - 701 EP - 710 VL - 544 KW - Drinking Water KW - 0 KW - Water Pollutants, Chemical KW - Arsenic KW - N712M78A8G KW - Index Medicus KW - Bottled water KW - Bathing KW - Well water KW - Point-of-use KW - Children KW - Family Characteristics KW - Environmental Monitoring KW - Humans KW - Water Purification KW - Maine KW - Arsenic -- analysis KW - Water Wells KW - Water Pollutants, Chemical -- analysis KW - Environmental Exposure -- statistics & numerical data KW - Drinking Water -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1764342257?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Science+of+the+total+environment&rft.atitle=Assessing+arsenic+exposure+in+households+using+bottled+water+or+point-of-use+treatment+systems+to+mitigate+well+water+contamination.&rft.au=Smith%2C+Andrew+E%3BLincoln%2C+Rebecca+A%3BPaulu%2C+Chris%3BSimones%2C+Thomas+L%3BCaldwell%2C+Kathleen+L%3BJones%2C+Robert+L%3BBacker%2C+Lorraine+C&rft.aulast=Smith&rft.aufirst=Andrew&rft.date=2016-02-15&rft.volume=544&rft.issue=&rft.spage=701&rft.isbn=&rft.btitle=&rft.title=The+Science+of+the+total+environment&rft.issn=1879-1026&rft_id=info:doi/10.1016%2Fj.scitotenv.2015.11.136 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2016-11-02 N1 - Date created - 2016-02-09 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Cited By: Environ Res. 2011 Jan;111(1):110-8 [21093857] Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20656-60 [22143778] J Contam Hydrol. 2008 Jul 29;99(1-4):8-21 [18571283] J Health Popul Nutr. 2006 Sep;24(3):298-304 [17366771] Environ Health Perspect. 2005 Feb;113(2):192-200 [15687057] J Nutr. 1994 Nov;124(11 Suppl):2245S-2317S [7965210] Am J Epidemiol. 1991 Nov 15;134(10):1233-44 [1746532] Environ Sci Technol. 2003 May 15;37(10):2075-83 [12785510] Toxicol Lett. 2002 Jul 7;133(1):77-82 [12076512] Stat Med. 2000 Dec 15;19(23):3171-91 [11113952] Sci Total Environ. 2015 Feb 1;505:1282-90 [24726512] Sci Total Environ. 2015 Feb 1;505:1274-81 [24875279] J Expo Sci Environ Epidemiol. 2014 Mar-Apr;24(2):156-62 [23860400] Anal Bioanal Chem. 2009 Feb;393(3):939-47 [19082583] J Expo Sci Environ Epidemiol. 2012 Mar-Apr;22(2):182-90 [21878987] Environ Health Perspect. 2012 Oct;120(10):1418-24 [23008276] Environ Health Perspect. 2013 Mar;121(3):295-302 [23458756] J Expo Sci Environ Epidemiol. 2013 Jul;23(4):442-9 [23321855] Environ Health Perspect. 2013 Jul;121(7):818-24 [23694900] Sci Total Environ. 2015 Feb 1;505:1361-9 [24975493] PLoS One. 2014;9(9):e108098 [25251890] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1016/j.scitotenv.2015.11.136 ER - TY - JOUR T1 - Vital Signs: Alcohol-Exposed Pregnancies--United States, 2011-2013. AN - 1762968643; 26845520 AB - Alcohol is a teratogen.* Prenatal alcohol exposure is associated with a range of adverse reproductive outcomes and can cause fetal alcohol spectrum disorders (FASDs) characterized by lifelong physical, behavioral, and intellectual disabilities. FASDs are completely preventable if a woman does not drink alcohol while pregnant. CDC analyzed data from the 2011-2013 National Survey of Family Growth to generate U.S. prevalence estimates of risk for an alcohol-exposed pregnancy for 4,303 nonpregnant, nonsterile women aged 15-44 years, by selected demographic and behavioral factors. A woman was considered at risk for an alcohol-exposed pregnancy during the past month if she had sex with a male, drank any alcohol, and did not (and her partner did not with her) use contraception in the past month; was not sterile; and had a partner (or partners) not known to be sterile. The weighted prevalence of alcohol-exposed pregnancy risk among U.S. women aged 15-44 years was 7.3%. During a 1-month period, approximately 3.3 million women in the United States were at risk for an alcohol-exposed pregnancy. Alcohol use in pregnancy is associated with low birthweight, preterm birth, birth defects, and developmental disabilities. Women of reproductive age should be informed of the risks of alcohol use during pregnancy, and contraception should be recommended, as appropriate, for women who do not want to become pregnant. Women wanting a pregnancy should be advised to stop drinking at the same time contraception is discontinued. Health care providers should advise women not to drink at all if they are pregnant or there is any chance they might be pregnant. Alcohol misuse screening and behavioral counseling (also known as alcohol screening and brief intervention) is recommended for all adults in primary care, including reproductive-aged and pregnant women, as an evidenced-based approach to reducing alcohol consumption among persons who consume alcohol in excess of the recommended guidelines. JF - MMWR. Morbidity and mortality weekly report AU - Green, Patricia P AU - McKnight-Eily, Lela R AU - Tan, Cheryl H AU - Mejia, Roberto AU - Denny, Clark H AD - Division of Birth Defects and Developmental Disabilities, National Center on Birth Defects and Developmental Disabilities, CDC. Y1 - 2016/02/05/ PY - 2016 DA - 2016 Feb 05 SP - 91 EP - 97 VL - 65 IS - 4 KW - Index Medicus KW - Young Adult KW - Risk KW - Humans KW - Adult KW - Adolescent KW - United States -- epidemiology KW - Female KW - Prevalence KW - Pregnancy KW - Alcohol Drinking -- epidemiology KW - Fetal Alcohol Spectrum Disorders -- epidemiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1762968643?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=MMWR.+Morbidity+and+mortality+weekly+report&rft.atitle=Vital+Signs%3A+Alcohol-Exposed+Pregnancies--United+States%2C+2011-2013.&rft.au=Green%2C+Patricia+P%3BMcKnight-Eily%2C+Lela+R%3BTan%2C+Cheryl+H%3BMejia%2C+Roberto%3BDenny%2C+Clark+H&rft.aulast=Green&rft.aufirst=Patricia&rft.date=2016-02-05&rft.volume=65&rft.issue=4&rft.spage=91&rft.isbn=&rft.btitle=&rft.title=MMWR.+Morbidity+and+mortality+weekly+report&rft.issn=1545-861X&rft_id=info:doi/10.15585%2Fmmwr.mm6504a6 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2016-06-07 N1 - Date created - 2016-02-05 N1 - Date revised - 2017-01-14 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.15585/mmwr.mm6504a6 ER - TY - JOUR T1 - A Novel Botulinum Neurotoxin, Previously Reported as Serotype H, Has a Hybrid-Like Structure With Regions of Similarity to the Structures of Serotypes A and F and Is Neutralized With Serotype A Antitoxin AN - 1773835196; PQ0002694574 AB - Botulism is a potentially fatal paralytic disease caused by the action of botulinum neurotoxin (BoNT) on nerve cells. There are 7 known serotypes (A-G) of BoNT and up to 40 genetic variants. Clostridium botulinum strain IBCA10-7060 was recently reported to produce BoNT serotype B (BoNT/B) and a novel BoNT, designated as BoNT/H. The BoNT gene (bont) sequence of BoNT/H was compared to known bont sequences. Genetic analysis suggested that BoNT/H has a hybrid-like structure containing regions of similarity to the structures of BoNT/A1 and BoNT/F5. This novel BoNT was serologically characterized by the mouse neutralization assay and a neuronal cell-based assay. The toxic effects of this hybrid-like BoNT were completely eliminated by existing serotype A antitoxins, including those contained in multivalent therapeutic antitoxin products that are the mainstay of human botulism treatment. JF - Journal of Infectious Diseases AU - Maslanka, Susan E AU - Luquez, Carolina AU - Dykes, Janet K AU - Tepp, William H AU - Pier, Christina L AU - Pellett, Sabine AU - Raphael, Brian H AU - Kalb, Suzanne R AU - Barr, John R AU - Rao, Agam AU - Johnson, Eric A AD - Centers for Disease Control and Prevention, Atlanta, Georgia, smaslanka@cdc.gov Y1 - 2016/02/01/ PY - 2016 DA - 2016 Feb 01 SP - 379 EP - 385 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 213 IS - 3 SN - 0022-1899, 0022-1899 KW - Health & Safety Science Abstracts KW - botulinum toxin KW - Clostridium botulinum KW - serotype KW - botulism KW - neutralization KW - neuronal cell-based assay KW - Antitoxins KW - Infectious diseases KW - Toxicity KW - Neurotoxins KW - Food contamination KW - Neutralization KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1773835196?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=A+Novel+Botulinum+Neurotoxin%2C+Previously+Reported+as+Serotype+H%2C+Has+a+Hybrid-Like+Structure+With+Regions+of+Similarity+to+the+Structures+of+Serotypes+A+and+F+and+Is+Neutralized+With+Serotype+A+Antitoxin&rft.au=Maslanka%2C+Susan+E%3BLuquez%2C+Carolina%3BDykes%2C+Janet+K%3BTepp%2C+William+H%3BPier%2C+Christina+L%3BPellett%2C+Sabine%3BRaphael%2C+Brian+H%3BKalb%2C+Suzanne+R%3BBarr%2C+John+R%3BRao%2C+Agam%3BJohnson%2C+Eric+A&rft.aulast=Maslanka&rft.aufirst=Susan&rft.date=2016-02-01&rft.volume=213&rft.issue=3&rft.spage=379&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiv327 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-03-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Antitoxins; Infectious diseases; Toxicity; Food contamination; Neurotoxins; Neutralization; Clostridium botulinum DO - http://dx.doi.org/10.1093/infdis/jiv327 ER - TY - JOUR T1 - Determination of Evolutionary Relationships of Outbreak-Associated Listeria monocytogenes Strains of Serotypes 1/2a and 1/2b by Whole-Genome Sequencing AN - 1765986131; PQ0002637597 AB - We used whole-genome sequencing to determine evolutionary relationships among 20 outbreak-associated clinical isolates of Listeria monocytogenes serotypes 1/2a and 1/2b. Isolates from 6 of 11 outbreaks fell outside the clonal groups or "epidemic clones" that have been previously associated with outbreaks, suggesting that epidemic potential may be widespread in L. monocytogenes and is not limited to the recognized epidemic clones. Pairwise comparisons between epidemiologically related isolates within clonal complexes showed that genome-level variation differed by 2 orders of magnitude between different comparisons, and the distribution of point mutations (core versus accessory genome) also varied. In addition, genetic divergence between one closely related pair of isolates from a single outbreak was driven primarily by changes in phage regions. The evolutionary analysis showed that the changes could be attributed to horizontal gene transfer; members of the diverse bacterial community found in the production facility could have served as the source of novel genetic material at some point in the production chain. The results raise the question of how to best utilize information contained within the accessory genome in outbreak investigations. The full magnitude and complexity of genetic changes revealed by genome sequencing could not be discerned from traditional subtyping methods, and the results demonstrate the challenges of interpreting genetic variation among isolates recovered from a single outbreak. Epidemiological information remains critical for proper interpretation of nucleotide and structural diversity among isolates recovered during outbreaks and will remain so until we understand more about how various population histories influence genetic variation. JF - Antimicrobial Agents & Chemotherapy AU - Bergholz, Teresa M AU - den Bakker, Henk C AU - Katz, Lee S AU - Silk, Benjamin J AU - Jackson, Kelly A AU - Kucerova, Zuzana AU - Joseph, Lavin A AU - Turnsek, Maryann AU - Gladney, Lori M AU - Halpin, Jessica L AD - << + $0, ctarr@cdc.gov. Y1 - 2016/02// PY - 2016 DA - February 2016 SP - 928 EP - 938 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 82 IS - 3 SN - 0099-2240, 0099-2240 KW - Biochemistry Abstracts 2: Nucleic Acids; Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Genomes KW - Clinical isolates KW - Phages KW - Listeria monocytogenes KW - Epidemics KW - Serotypes KW - Point mutation KW - Genetic diversity KW - Nucleotides KW - Population genetics KW - Gene transfer KW - Information processing KW - Evolution KW - A 01340:Antibiotics & Antimicrobials KW - J 02400:Human Diseases KW - N 14810:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1765986131?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Determination+of+Evolutionary+Relationships+of+Outbreak-Associated+Listeria+monocytogenes+Strains+of+Serotypes+1%2F2a+and+1%2F2b+by+Whole-Genome+Sequencing&rft.au=Bergholz%2C+Teresa+M%3Bden+Bakker%2C+Henk+C%3BKatz%2C+Lee+S%3BSilk%2C+Benjamin+J%3BJackson%2C+Kelly+A%3BKucerova%2C+Zuzana%3BJoseph%2C+Lavin+A%3BTurnsek%2C+Maryann%3BGladney%2C+Lori+M%3BHalpin%2C+Jessica+L&rft.aulast=Bergholz&rft.aufirst=Teresa&rft.date=2016-02-01&rft.volume=82&rft.issue=3&rft.spage=928&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00992240&rft_id=info:doi/10.1128%2FAEM.02440-15 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Number of references - 54 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Phages; Clinical isolates; Genomes; Population genetics; Serotypes; Epidemics; Gene transfer; Information processing; Point mutation; Genetic diversity; Nucleotides; Evolution; Listeria monocytogenes DO - http://dx.doi.org/10.1128/AEM.02440-15 ER - TY - JOUR T1 - Arsenic and Gallium Arsenide Exposure Levels and Workers' Health Conditions in an Enterprise AN - 1780507149; PQ0002837803 AB - The objective of this paper is to evaluate workers' exposure to arsenic and gallium arsenide and health conditions in a gallium arsenide processing enterprise. Following the Specifications of Air Sampling for Hazardous Substances Monitoring in the Workplace (GBZ 159-2004), 147 arsenic and gallium arsenide air samples in 29 sampling points were collected. Occupational health examinations were conducted according to the Technical Specifications for Occupational Health Surveillance (GBZ 188-2007), and surveys included medical history, occupational history, and family history of diseases. SPSS 17.0 software was applied to analyze the workplace monitoring results and 327 workers' occupational health examination results through chi-square test and rank sum test In the enterprise investigated, most workers are exposed to low concentrations of arsenic and show skin damage and ALT abnormalities, and only a small part of workers performing specific tasks are exposed to relative high concentrations of arsenic. Therefore, the enterprise should pay attention to the health conditions of workers on key positions and high fluoride. JF - Huanjing yu Zhiye Yixue(Journal of Environmental & Occupational Medicine AU - Li, Qiu-hong AD - Department of Occupational Health, Tongzhou District Center for Disease Control and Prevention Y1 - 2016/01/25/ PY - 2016 DA - 2016 Jan 25 SP - 13 EP - 17 PB - Shanghai Shi Jibing Fangkongzhi Zhongxin, 1326 Yan'an Rd. Shanghai, 2000052 China VL - 33 IS - 1 SN - 2095-9982, 2095-9982 KW - Health & Safety Science Abstracts KW - arsenic KW - gallium arsenide KW - working environment KW - occupational exposure KW - health effect KW - Historical account KW - Genetics KW - Computer programs KW - Arsenic KW - Gallium KW - Skin KW - Fluoride KW - Air sampling KW - Occupational exposure KW - Occupational health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1780507149?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Huanjing+yu+Zhiye+Yixue%28Journal+of+Environmental+%26+Occupational+Medicine&rft.atitle=Arsenic+and+Gallium+Arsenide+Exposure+Levels+and+Workers%27+Health+Conditions+in+an+Enterprise&rft.au=Li%2C+Qiu-hong&rft.aulast=Li&rft.aufirst=Qiu-hong&rft.date=2016-01-25&rft.volume=33&rft.issue=1&rft.spage=13&rft.isbn=&rft.btitle=&rft.title=Huanjing+yu+Zhiye+Yixue%28Journal+of+Environmental+%26+Occupational+Medicine&rft.issn=20959982&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-04-01 N1 - Last updated - 2016-04-29 N1 - SubjectsTermNotLitGenreText - Computer programs; Genetics; Historical account; Arsenic; Skin; Gallium; Fluoride; Air sampling; Occupational exposure; Occupational health ER - TY - JOUR T1 - Seroprevalence of 9 Human Papillomavirus Types in the United States, 2005-2006 AN - 1773839233; PQ0002694557 AB - Background. A 9-valent human papillomavirus (HPV) vaccine, licensed in 2014, prevents 4 HPV types targeted by the quadrivalent vaccine (6/11/16/18) and 5 additional high-risk (HR) types (31/33/45/52/58). Measuring seropositivity before vaccine introduction provides baseline data on exposure to types targeted by vaccines. Methods. We determined seroprevalence of HPV 6/11/16/18/31/33/45/52/58 among 4943 persons aged 14-59 years who participated in the National Health and Nutrition Examination Survey, 2005-2006. Results. Among females, seroprevalence was 40.5% for any of the 9 vaccine types, 30.0% for any 7 HR types (16/18/31/33/45/52/58), 19.0% for any 5 additional types (31/33/45/52/58), and 18.3% for 16/18. Compared with non-Hispanic whites, non-Hispanic blacks had higher seroprevalence of 31/33/45/52/58 (36.8% vs 15.9%) and 16/18 (30.1% vs 17.8%), while Mexican Americans had higher seroprevalence of 31/33/45/52/58 (23.6% vs 15.9%) (P or =1 of 9 HPV types. Seroprevalence of all type categories, especially HPV 31/33/45/52/58 among females, varied by race/ethnicity. JF - Journal of Infectious Diseases AU - Liu, Gui AU - Markowitz, Lauri E AU - Hariri, Susan AU - Panicker, Gitika AU - Unger, Elizabeth R AD - Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, wrf8@cdc.gov Y1 - 2016/01/15/ PY - 2016 DA - 2016 Jan 15 SP - 191 EP - 198 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 213 IS - 2 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - human papillomavirus KW - seroprevalence KW - racial differences KW - Age KW - Data processing KW - Nutrition KW - USA KW - Infectious diseases KW - Risk groups KW - Vaccines KW - Races KW - Ethnic groups KW - Human papillomavirus KW - Sex KW - V 22490:Miscellaneous KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1773839233?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Seroprevalence+of+9+Human+Papillomavirus+Types+in+the+United+States%2C+2005-2006&rft.au=Liu%2C+Gui%3BMarkowitz%2C+Lauri+E%3BHariri%2C+Susan%3BPanicker%2C+Gitika%3BUnger%2C+Elizabeth+R&rft.aulast=Liu&rft.aufirst=Gui&rft.date=2016-01-15&rft.volume=213&rft.issue=2&rft.spage=191&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiv403 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-03-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Age; Data processing; Risk groups; Vaccines; Nutrition; Ethnic groups; Races; Sex; Infectious diseases; Human papillomavirus; USA DO - http://dx.doi.org/10.1093/infdis/jiv403 ER - TY - JOUR T1 - A Fatal Case Report on Occupational Subacute Dimethylformamide Poisoning AN - 1859472294; PQ0003969502 AB - In order to better prevent and treat dimethylformamide (DMF) poisoning and to provide cases on individual sensitivity to DMF and interpersonal variation,a special fatal DMF poisoning case who operated three roll mills in the grinding workshop of a color paste plant was reported and analyzed. The poisoning case might be sensitive to dimethylformamide. DMF individual sensitivity needs further study. JF - Huanjing yu Zhiye Yixue(Journal of Environmental & Occupational Medicine AU - Zheng, Shuang-lai AD - Public Health Surveillance Department , Hangzhou City Yuhang District Center for Disease Control and Prevention, Hangzhou, Zhejiang 311100 Y1 - 2016///0, PY - 2016 DA - 0, 2016 SP - 1005 EP - 1007 PB - Shanghai Shi Jibing Fangkongzhi Zhongxin, 1326 Yan'an Rd. Shanghai, 2000052 China VL - 33 IS - 10 SN - 2095-9982, 2095-9982 KW - Health & Safety Science Abstracts KW - occupational KW - dimethylformamide KW - poisoning KW - death UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1859472294?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Q+Fever+is+Underestimated+in+the+United+States%3A+A+Comparison+of+Fatal+Q+Fever+Cases+from+Two+National+Reporting+Systems&rft.au=Dahlgren%2C+F+Scott%3BHaberling%2C+Dana+L%3BMcQuiston%2C+Jennifer+H&rft.aulast=Dahlgren&rft.aufirst=F&rft.date=2015-02-01&rft.volume=92&rft.issue=2&rft.spage=244&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0502 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2017-01-01 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.13213/j.cnki.jeom.2016.16190 ER - TY - JOUR T1 - Drug resistance and failure of virus inhibition after antiviral therapy among injecting drug users with HIV/AIDS AN - 1850769278; PQ0003905074 AB - Objective To understand the failure of virus inhibition and drug resistance among injecting drug users(IDU)with HIV/AIDS after antiretroviral therapy(ART)in China. Methods Data of basic demographic characteristics,ART information,CD4+cell count,viral load and drug resistance among IDUs with HIV/AIDS were retrieved from the Chinese HIV Drug Resistance(HIV DR)Monitoring Network,factors of viral inhibition failure and drug-resistance were evaluated. Results A total of 1 395 IDUs with HIV/AIDS were included in our study and the average ART month was 23.9.298(21.4%)subjects failed on the virus inhibition(VL> or =1 000copies/ml).The overall drug resistance rate was 8.4%(117/1 395)with 65.0%to NRTIs,69.2% to NNRTIs and 7.7% to PIs.Multivariate logistic regression analysis showed that the higher rates of virus inhibition failure occurred among IDUs with HIV/AIDS who were ethnic minorities(AOR=2.1,95% CI:1.6-2.9),recently received ART containing LPV/r(AOR=3.6,95% CI:2.4-5.4),did not take medicine in the most recent month(AOR=2.0,95% CI:1.4-3.0),started ART in 2011-2013(AOR=2.2,95% CI:1.5-3.2).While,IDUs aged over 35years(AOR=0.7,95% CI:0.6-1.0),were from Guangxi and Yunnan provinces(AOR=0.3,95% CI:0.2-0.5)had lower failure rate of virus inhibition. Conclusions The overall failure rate of virus inhibition among IDUs with HIV/AIDS remains in a higher level after ART,but it is relatively lower among those in Guangxi and Yunnan.The major influencing factor is found to be medication compliance. JF - Chinese Journal of Viral Diseases (Zhongguo Bingdubing Zazhi) AU - Teng, Tao AU - Leng, Xue-bing AU - Liang, Shu-jia AU - Ma, Yan-ling AU - Sun, Zhe-ya AU - Xu, Wei AU - Liao, Ling-jie AU - Xing, Hui AU - Ruan, Yu-hua AU - Shao, Yi-ming AD - State Key Laboratory for Infectious Disease Prevention and Control,National Center for AIDS/STD Control and Prevention,Chinese Center for Disease Control and Prevention Y1 - 2016///0, PY - 2016 DA - 0, 2016 PB - Periodical Editorial Department of Chinese Preventive Medicine Association, 154 Gulouxida Street, Xicheng District Beijing 100009 China VL - 6 IS - 2 SN - 2095-0136, 2095-0136 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Virology & AIDS Abstracts KW - Antiretroviral therapy KW - IDUs KW - HIV/AIDS KW - Virus inhibition failure KW - Drug resistance KW - Adherence KW - Demography KW - Acquired immune deficiency syndrome KW - Data processing KW - Lentivirus KW - Antiviral agents KW - Retroviridae KW - antiretroviral therapy KW - Regression analysis KW - Drug abuse KW - A 01340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1850769278?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chinese+Journal+of+Viral+Diseases+%28Zhongguo+Bingdubing+Zazhi%29&rft.atitle=Drug+resistance+and+failure+of+virus+inhibition+after+antiviral+therapy+among+injecting+drug+users+with+HIV%2FAIDS&rft.au=Teng%2C+Tao%3BLeng%2C+Xue-bing%3BLiang%2C+Shu-jia%3BMa%2C+Yan-ling%3BSun%2C+Zhe-ya%3BXu%2C+Wei%3BLiao%2C+Ling-jie%3BXing%2C+Hui%3BRuan%2C+Yu-hua%3BShao%2C+Yi-ming&rft.aulast=Teng&rft.aufirst=Tao&rft.date=2016-01-01&rft.volume=6&rft.issue=2&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Chinese+Journal+of+Viral+Diseases+%28Zhongguo+Bingdubing+Zazhi%29&rft.issn=20950136&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-12-01 N1 - Last updated - 2017-01-18 N1 - SubjectsTermNotLitGenreText - Demography; Acquired immune deficiency syndrome; Data processing; Antiviral agents; Drug resistance; antiretroviral therapy; Regression analysis; Drug abuse; Lentivirus; Retroviridae ER - TY - JOUR T1 - Association between gut microbiota of maternal obesity and children obesity AN - 1837307185; PQ0003808028 AB - With the rising of its incidence rate around the world,gestational obesity has become a public health problem affecting human health.The gut microbiota dysbiosis of obesity mother leads to abnormal colonization of infant at early stage,and the latter is closely related to the growth and development of infant in the future.Dysbiosis of gut microbiota is liable to cause adult diseases such as obesity,insulin resistance and metabolic syndrome et al.Hence,analyses of gut microbiota of obese pregnant women and infants,as well as the growth and development of babies,are of great significances for pregnancy management,health education and improvement of national physical quality. JF - Chinese Journal of Microecology AU - Zhang, Ye AU - Sui, Xuelin AU - Liu, Chengcheng AU - Yuan, Jieli AU - Guo, Yanjie AD - Center for Disease Control and Prevention of Shahekou District Dalian Y1 - 2016///0, PY - 2016 DA - 0, 2016 SP - 1107 EP - 1109 PB - Editorial Department of Chinese Journal of Microecology, 465 Zhongshan Road Dalian 116027 China VL - 28 IS - 9 SN - 1005-376X, 1005-376X KW - Microbiology Abstracts A: Industrial & Applied Microbiology KW - Obesity KW - Pregnant woman KW - Infant KW - Gut microbiota KW - Colonization KW - Digestive tract KW - Metabolic disorders KW - Children KW - Pregnancy KW - Infants KW - Public health KW - A 01450:Environmental Pollution & Waste Treatment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1837307185?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chinese+Journal+of+Microecology&rft.atitle=Association+between+gut+microbiota+of+maternal+obesity+and+children+obesity&rft.au=Zhang%2C+Ye%3BSui%2C+Xuelin%3BLiu%2C+Chengcheng%3BYuan%2C+Jieli%3BGuo%2C+Yanjie&rft.aulast=Zhang&rft.aufirst=Ye&rft.date=2016-01-01&rft.volume=28&rft.issue=9&rft.spage=1107&rft.isbn=&rft.btitle=&rft.title=Chinese+Journal+of+Microecology&rft.issn=1005376X&rft_id=info:doi/ LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-11-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Colonization; Obesity; Digestive tract; Metabolic disorders; Children; Public health; Infants; Pregnancy ER - TY - JOUR T1 - Characteristics of complete genome of an Oseltamivir-resistant influenza A(H1N1) pdm09 virus AN - 1837300878; PQ0003807972 AB - Objective To analyze the complete genetic characteristics of an Oseltamivir-resistant influenza A(H1N1)pdm09virus in order to provide a basis for treatment and prevention.Methods The viral RNA was extracted form chicken embryo culture inoculated with throat swab,and genome fragments were amplified by RT-PCR.The PCR products were sequenced and the complete genome sequence was obtained and analyzed via bioinformatics.Results Eight genome fragments of A/Fuzhou/SWL11609/2013(H1N1)were part of viruses cluster(2013-2014)and were closely related to those of A/California/07/2009(H1N1)vaccine strain,with the homologies> or = 97.4%.Nevertheless,its HA and NA genes were similar to the A/Hubei-Wuchang/SWL1322/2013(H1N1)(Oseltamivir-resistant influenza virus),with a similarity of100.0% and 99.6% respectively.Phylogenetic analysis showed initially that genetic reassortment had not occurred in the virus,neither had mutations at key pathogenic sites,so the virus strain was a low-pathogenic influenza virus.The H275 Ysubstitution was a typical feature of Oseltamivir-resistant genetic mutation.The N386 Ksubstitution resulted in the loss of a glycosylation site in the NA protein,which reduced the stability of gene structure in the presence of the V241 Iand N369Ksubstitutions,causing a negative effect on virus fitness.Conclusion The A/Fuzhou/SWL11609/2013(H1N1)virus was a low-pathogenic influenza virus,but still had the capability of human-to-human transmission,so more attention should be paid to the surveillance in order to control the increasing risk of wide spreading of Oseltamivir-resistant influenza virus. JF - Chinese Journal of Microecology AU - Xie, Jianfeng AU - Zhang, Yanhua AU - Zhao, Lin AU - Xiu, Wenqiong AU - Chen, Hongbin AU - Weng, Yuwei AU - Zheng, Kuicheng AD - Fujian Center for Disease Control and Prevention Y1 - 2016///0, PY - 2016 DA - 0, 2016 SP - 884 EP - 888 PB - Editorial Department of Chinese Journal of Microecology, 465 Zhongshan Road Dalian 116027 China VL - 28 IS - 8 SN - 1005-376X, 1005-376X KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Virology & AIDS Abstracts KW - Influenza A(H1N1)pdm09 virus KW - Oseltamivir-resistant KW - Genetic characteristics KW - Genomes KW - Spreading KW - Pharynx KW - Nucleotide sequence KW - Glycosylation KW - Orthomyxoviridae KW - Influenza KW - Homology KW - RNA KW - Polymerase chain reaction KW - Embryos KW - Mutation KW - V 22410:Animal Diseases KW - A 01330:Food Microbiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1837300878?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chinese+Journal+of+Microecology&rft.atitle=Characteristics+of+complete+genome+of+an+Oseltamivir-resistant+influenza+A%28H1N1%29+pdm09+virus&rft.au=Xie%2C+Jianfeng%3BZhang%2C+Yanhua%3BZhao%2C+Lin%3BXiu%2C+Wenqiong%3BChen%2C+Hongbin%3BWeng%2C+Yuwei%3BZheng%2C+Kuicheng&rft.aulast=Xie&rft.aufirst=Jianfeng&rft.date=2016-01-01&rft.volume=28&rft.issue=8&rft.spage=884&rft.isbn=&rft.btitle=&rft.title=Chinese+Journal+of+Microecology&rft.issn=1005376X&rft_id=info:doi/ LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-11-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Genomes; Influenza; Pharynx; Spreading; RNA; Homology; Nucleotide sequence; Polymerase chain reaction; Embryos; Glycosylation; Mutation; Orthomyxoviridae ER - TY - JOUR T1 - Detection and homological analysis of metallo- beta -lactamase genes,intI gene and ISCR1 in carbapenem-resistant Pseudomonas aeruginosa AN - 1827920011; PQ0003672900 AB - Objective To investigate the distribution of metallo-beta-lactamase,integron I and ISCR1,and analyze the characteristics of gene polymorphism in carbapenem resistant Pseudomonas aeruginosain Dalian.Methods 89 strains of clinical isolates of imipenem resistant Pseudomonas aeruginosa were collected.PCR was used to detect the resistant genes of metallo enzyme,integron I and ISCR1.Bacterial genotypes were detected by using Pulsed field gel electrophoresis(PFGE).Results Of the 89 strains of imipenem resistant Pseudomonas aeruginosa,25 strains carried ISCR1gene(25/89,28%),21isolates(21/25,84%)of which were multi-drug-resistant while 16 isolates were resistant to 5or more kinds of drugs.11 strains carried metallo-beta-lactamase gene(11/89,12%),8strains of which carried IMP-1gene and 3strains carried VIM-2gene.43 strains were integron I positive(43/89,48%).Strains carrying metallo-beta-lactamase gene were integron I negative and ISCR1 negative.PFGE showed 15 distinct PFGE genotypes(A-O),including 46 strains of type A,16 strains of type B,4strains of type C,5strains of type D,4strains of type E,3strains of type F,2strains of type G,2strains of type H,and 1strain each from type I to type O.Genotypes A to G were isolated from different hospitals and presented polymorphism; there were clones of each genotype.Conclusion The integron I and ISCR1 genes widely distributed among Pseudomonas aeruginosa in Dalian,which significantly correlated with bacterial multidrug resistance and extensively drug-resistance,especially the ISCR1 gene.The strains carrying integron I and ISCR1 did not carry metallo-beta-lactamase gene cassettes.Pseudomonas aeruginosain Dalian present genetic polymorphism,but there was dominant genotype. JF - Chinese Journal of Microecology AU - Wan, Qiang AU - Lyu, Qiuyue AU - Chen, Yang AD - Dalian Center for Disease Control and Prevention Y1 - 2016///0, PY - 2016 DA - 0, 2016 SP - 786 EP - 790 PB - Editorial Department of Chinese Journal of Microecology, 465 Zhongshan Road Dalian 116027 China VL - 28 IS - 7 SN - 1005-376X, 1005-376X KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology KW - Carbapenem-resistant Pseudomonas aeruginosa KW - Integron KW - ISCR1 KW - PFGE KW - Clinical isolates KW - Gene polymorphism KW - Carbapenems KW - Multidrug resistance KW - Pseudomonas aeruginosa KW - Imipenem KW - Hospitals KW - J 02400:Human Diseases KW - A 01350:Microbial Resistance UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1827920011?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chinese+Journal+of+Microecology&rft.atitle=Detection+and+homological+analysis+of+metallo-+beta+-lactamase+genes%2CintI+gene+and+ISCR1+in+carbapenem-resistant+Pseudomonas+aeruginosa&rft.au=Wan%2C+Qiang%3BLyu%2C+Qiuyue%3BChen%2C+Yang&rft.aulast=Wan&rft.aufirst=Qiang&rft.date=2016-01-01&rft.volume=28&rft.issue=7&rft.spage=786&rft.isbn=&rft.btitle=&rft.title=Chinese+Journal+of+Microecology&rft.issn=1005376X&rft_id=info:doi/ LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-10-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Clinical isolates; Gene polymorphism; Carbapenems; Multidrug resistance; Hospitals; Imipenem; Pseudomonas aeruginosa ER - TY - JOUR T1 - Virological characterization of influenza-like illness in Yuxi during 2009-2014 AN - 1808741479; PQ0003354823 AB - Objective To understand the epidemiologic characteristics of influenza and the changes of epidemic strains in Yuxi,and provide scientific basis for the disease control and prevention.Methods MDCK cells were used to culture the viruses,and the final influenza viruses were identified with influenza typing reagent.Results Among the total 3,248 cases monitored from 2009 to 2014,there were 489 positive specimens; the positive rate was 15.06%.New H1N1,H3N2 and influenza B accounted for 43.97%,28.22% and25.36%,respectively.Students and retirees accounted for 52.15% and 14.11% of the positive cases,respectively.The positive rate of influenza-like specimens from sentinel hospitals was significantly lower than that from flu outbreaks([chi]2=301.14,P<0.01).The peak flu season ran from October to March annually,with the predominant virus being new H1N1 from October 2009 to March 2011,influenza B from April2011 to March 2012,H3N2 from April 2012 to March 2013,and influenza B from April 2013 to March2014,respectively.Conclusion New H1N1,H3N2 and influenza B are the predominant virulent strains in Yuxi,which changed four times during 2009 and 2014,and may possibly keep changing in future.Therefore,it is necessary to strengthen the etiological monitoring of influenza-like cases and epidemic surveillance in priority crowds. JF - Chinese Journal of Microecology AU - Yang, Ru-song AU - Liu, Hong-yan AU - Ni, Zhao-lin AU - Zuo, Shun-wu AU - Wu, Qiang AU - Wang, Shu-kun AD - Center for Disease Control and Prevention of Yuxi Y1 - 2016///0, PY - 2016 DA - 0, 2016 SP - 267 EP - 270 PB - Editorial Department of Chinese Journal of Microecology, 465 Zhongshan Road Dalian 116027 China VL - 28 IS - 3 SN - 1005-376X, 1005-376X KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Virology & AIDS Abstracts KW - Influenza KW - Influenza virus KW - Epidemiology KW - Prevention KW - Influenza B KW - Epidemics KW - Typing KW - Disease control KW - Cell culture KW - Hospitals KW - A 01380:Plant Protection, Fungicides & Seed Treatments KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808741479?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chinese+Journal+of+Microecology&rft.atitle=Virological+characterization+of+influenza-like+illness+in+Yuxi+during+2009-2014&rft.au=Yang%2C+Ru-song%3BLiu%2C+Hong-yan%3BNi%2C+Zhao-lin%3BZuo%2C+Shun-wu%3BWu%2C+Qiang%3BWang%2C+Shu-kun&rft.aulast=Yang&rft.aufirst=Ru-song&rft.date=2016-01-01&rft.volume=28&rft.issue=3&rft.spage=267&rft.isbn=&rft.btitle=&rft.title=Chinese+Journal+of+Microecology&rft.issn=1005376X&rft_id=info:doi/ LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-09-01 N1 - SubjectsTermNotLitGenreText - Influenza; Influenza B; Typing; Epidemics; Disease control; Cell culture; Hospitals ER - TY - JOUR T1 - Detection of Metallo-[beta]-lactamase gene and antibiotics resistance of Imipenem-resistant Pseudomonas aeruginosain Dalian area AN - 1808739472; PQ0003354858 AB - Objective To investigate the drug resistance of Carbapenem-resistant Pseudomonas aeruginosa(PA)in Dalian area,and provide reference for the prevention and control of nosocomial infections.Methods 400 clinical isolates of Pseudomonas aeruginosa were collected from four tertiary hospitals in Dalian during January 2013 to September 2014; Identification of isolates and antimicrobial susceptibility testing were performed.E-test(IPM/EDTA)method was used to detect MBL phenotype; PCR was applied to detect MBL genes(IMP-K,IMP-2,VIM-1,VIM-2,GIM,SPM,SIM and NDM).Results The 400 Pseudomonas aeruginosa were mainly isolated from respiratory tract secretion,accounting for 81.5%,most of which were from respiratory department(19.8%)and ICU ward(25.5%).89 strains were resistant to Imipenem and most of them were multidrug-resistant.17 strains of Imipenem-resistant isolates were MBL positive,accounting for 19.1%(17/89),while most of Imipenem sensitive strains were MBL negative.PCR amplification showed that 11 strains of Imipenem-resistant isolates carried MBL genes,among which 8strains carried IMP-1gene and 3strains carried VIM-2gene.IMP-2,VIM-1,GIM,SPM,SIM and NDM genes were not found.Conclusion The Imipenem-resistant PA in Dalian area are often multidrug resistant; The genes producing metallo-[beta]-lactamase and metallo-[beta]-lactamase are one of the main mechanisms of drug resistance of Pseudomonas aeruginosa to Imipenem,and the main genotypes are IMP-1and VIM-2. JF - Chinese Journal of Microecology AU - Wan, Qiang AU - Bo, Zhi-jian AU - Chen, Yang AD - Dalian Center for Disease Control and Prevention Y1 - 2016///0, PY - 2016 DA - 0, 2016 SP - 405 EP - 408 PB - Editorial Department of Chinese Journal of Microecology, 465 Zhongshan Road Dalian 116027 China VL - 28 IS - 4 SN - 1005-376X, 1005-376X KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology KW - Pseudomonas aeruginosa KW - Drug-resistance KW - Metallo-[beta]-lactamase KW - Clinical isolates KW - Drug resistance KW - Genotypes KW - Antibiotic resistance KW - Imipenem KW - Hospitals KW - Antimicrobial agents KW - Respiratory tract KW - A 01340:Antibiotics & Antimicrobials KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808739472?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chinese+Journal+of+Microecology&rft.atitle=Detection+of+Metallo-%5Bbeta%5D-lactamase+gene+and+antibiotics+resistance+of+Imipenem-resistant+Pseudomonas+aeruginosain+Dalian+area&rft.au=Wan%2C+Qiang%3BBo%2C+Zhi-jian%3BChen%2C+Yang&rft.aulast=Wan&rft.aufirst=Qiang&rft.date=2016-01-01&rft.volume=28&rft.issue=4&rft.spage=405&rft.isbn=&rft.btitle=&rft.title=Chinese+Journal+of+Microecology&rft.issn=1005376X&rft_id=info:doi/ LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Clinical isolates; Drug resistance; Genotypes; Antibiotic resistance; Respiratory tract; Antimicrobial agents; Hospitals; Imipenem; Pseudomonas aeruginosa ER - TY - JOUR T1 - The expression of inflammatory cytokines mRNA in blood of child patients with enterovirus 71 infection AN - 1808739271; PQ0003354791 AB - Objective To investigate the expression of inflammatory cytokines in blood of child patients with enterovirus 71(EV71)infection.Methods The expressions of Tumor necrosis factor-[alpha](TNF-[alpha]),Interferon-[alpha](IFN-[alpha]),IFN-[b e ta],Interleukin6(IL-6),IL-8and IL-12 mRNA in blood of children with mild or severe EV71 infection and healthy children were detected by Real-time PCR.Results The expressions of IFN-[alpha],IL-6,IL-8and IL-12 mRNA in blood increased in children with EV71infection(28+ or -182.07 vs 5.5+ or -0.79; 30+ or -103.30 vs 6+ or -4.21; 34+ or -169.60 vs 6.2+ or -4.16; 33.33+ or -229.7 vs 2.6+ or -0.92).The expressions of IFN-[alpha]and IL-12 mRNA were significantly higher in children with severe infection than those with mild EV71infection(40+ or -275.86 vs 28+ or -182.07; 46.67+ or -46.04 vs 33.33+ or -229.7).There was no significant difference in the expressions of IL-6and IL-8mRNA between children with mild and severe EV71infection(30+ or -103.3 vs 32+ or -110.5; 34+ or -169.6 vs 36.67+ or -195.4).Conclusion IFN-[alpha],IL-6,IL-8and IL-12 involve in the process of resistance to EV71 infection.IFN-[alpha]and IL-12 may be the key factors that contribute to the development of severe infection with EV71. JF - Chinese Journal of Microecology AU - Luan, Ming-chun AU - An, Yu AU - Chen, Yu-feng AU - Bo, Zhi-jian AU - Lyu, Qiu-yue AU - Liu, Dan-hong AD - Dalian Center for Disease Control and Prevention Y1 - 2016///0, PY - 2016 DA - 0, 2016 SP - 138 EP - 140 PB - Editorial Department of Chinese Journal of Microecology, 465 Zhongshan Road Dalian 116027 China VL - 28 IS - 2 SN - 1005-376X, 1005-376X KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Immunology Abstracts; Virology & AIDS Abstracts KW - Enterovirus 71 KW - Hand-foot-and-mouth disease KW - Cytokines KW - Interleukin 6 KW - Interleukin 12 KW - Blood KW - Enterovirus KW - Children KW - Infection KW - mRNA KW - Inflammation KW - A 01490:Miscellaneous KW - V 22370:Oncology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808739271?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chinese+Journal+of+Microecology&rft.atitle=The+expression+of+inflammatory+cytokines+mRNA+in+blood+of+child+patients+with+enterovirus+71+infection&rft.au=Luan%2C+Ming-chun%3BAn%2C+Yu%3BChen%2C+Yu-feng%3BBo%2C+Zhi-jian%3BLyu%2C+Qiu-yue%3BLiu%2C+Dan-hong&rft.aulast=Luan&rft.aufirst=Ming-chun&rft.date=2016-01-01&rft.volume=28&rft.issue=2&rft.spage=138&rft.isbn=&rft.btitle=&rft.title=Chinese+Journal+of+Microecology&rft.issn=1005376X&rft_id=info:doi/ LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-10-26 N1 - SubjectsTermNotLitGenreText - Interleukin 6; Blood; Interleukin 12; Infection; Children; Inflammation; mRNA; Enterovirus ER - TY - JOUR T1 - The drug resistance and molecular typing of S.typhoidstrains in Dalian in 2014 AN - 1808739196; PQ0003354856 AB - Objective To investigate the antibiotic resistance and molecular types of Salmonella typhi isolated in Dalian,establish the background information of molecular characteristics of Salmonella typhi,and provide scientific evidences for future prevention and control.Methods Broth dilution technique was used to test the sensitivity of 46 strains of Salmonella typhi to 8antibiotics.Pulsed field gel-electrophoresis(PFGE)was used for molecular typing and cluster analysis of the 46 strains.Results All 46 strains of Salmonella typhi were sensitive to nalidixic acid.The drug resistance rates of the 46 strains of Salmonella typhi were 4.35%to chloramphenicol and trimethoprim/sulfamethoxazole respectively,and 47.83% to gentamycin.A multiple drug resistant strain was found.The 46 isolates were classified into 30 types by PFGE and only 7strains were classified into the same type.Conclusion Some Salmonella typhi strains in Dalian are resistant to gentamycin.PFGE result revealed that they present a genetic polymorphism,and there exist dominant strains. JF - Chinese Journal of Microecology AU - Hou, Jun AU - Chen, Yu-feng AU - Luan, Ming-chun AU - Wang, Xiao-wei AU - Li, Bo-sheng AU - Sun, Mao-li AU - Yu, Lei AU - Bo, Zhi-jian AU - Li, Rui AD - Dalian Center for Disease Control and Prevention Y1 - 2016///0, PY - 2016 DA - 0, 2016 SP - 396 EP - 399 PB - Editorial Department of Chinese Journal of Microecology, 465 Zhongshan Road Dalian 116027 China VL - 28 IS - 4 SN - 1005-376X, 1005-376X KW - Microbiology Abstracts A: Industrial & Applied Microbiology KW - Salmonella typhi KW - Antimicrobial resistance KW - Pulsed field gel-electrophoresis KW - Trimethoprim KW - Chloramphenicol KW - Typing KW - Sulfamethoxazole KW - Drug resistance KW - Antibiotic resistance KW - A 01340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808739196?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Vermiculite+Worker+Mortality%3A+Estimated+Effects+of+Occupational+Exposure+to+Libby+Amphibole&rft.au=Larson%2C+T+C%3BAntao%2C+V+C%3BBove%2C+F+J&rft.aulast=Larson&rft.aufirst=T&rft.date=2010-05-01&rft.volume=52&rft.issue=5&rft.spage=555&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e3181dc6d45 LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-08-17 N1 - SubjectsTermNotLitGenreText - Chloramphenicol; Trimethoprim; Typing; Sulfamethoxazole; Drug resistance; Antibiotic resistance; Salmonella typhi ER - TY - JOUR T1 - Strain features and distributions in pneumococci from children with invasive disease before and after 13-valent conjugate vaccine implementation in the USA: Bacteriology AN - 1808691839; PQ0003310975 AB - The effect of second-generation pneumococcal conjugate vaccines on invasive pneumococcal disease (IPD) strain distributions have not yet been well described. We analysed IPD isolates recovered from children aged 95% for PI-2 and combined PI-1 + PI-2). beta -Lactam susceptibility phenotypes correlated consistently with transpeptidase region sequence combinations of the three major penicillin-binding proteins (PBPs) determined through WGS analysis. Other major resistance features were predictable by DNA signatures from WGS analysis. Multilocus sequence data combined with PBP combinations identified progeny, serotype donors and recipient strains in serotype switch events. PCV13 decreased the frequency of all PCV13 serotype clones and concurrently decreased the frequency of strain subsets with resistance and/or adherence features conducive to successful carriage. Our results serve as a reference describing key features of current paediatric IPD strains in the USA after PCV13 implementation. JF - Clinical Microbiology and Infection AU - Metcalf, B J AU - Gertz, RE Jr AU - Gladstone, R A AU - Walker, H AU - Sherwood, L K AU - Jackson, D AU - Li, Z AU - Law, C AU - Hawkins, P A AU - Chochua, S AU - Sheth, M AU - Rayamajhi, N AU - Bentley, S D AU - Kim, L AU - Whitney, C G AU - McGee, L AU - Beall, B AD - Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases, Atlanta, GA, USA Y1 - 2016/01// PY - 2016 DA - January 2016 SP - 60.e9 EP - 60.e29 PB - Elsevier Science Ltd., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 22 IS - 1 SN - 1198-743X, 1198-743X KW - Microbiology Abstracts B: Bacteriology KW - Antimicrobial susceptibility KW - clonal complexes KW - pneumococcal conjugate vaccines KW - serotype distributions KW - whole genome sequence KW - Genomes KW - Bacteria KW - Data processing KW - Serotypes KW - Pediatrics KW - Nucleotide sequence KW - Drug resistance KW - penicillin-binding protein KW - Genotypes KW - Children KW - Mass spectroscopy KW - Streptococcus pneumoniae KW - Combined vaccines KW - beta -Lactam antibiotics KW - Polymerase chain reaction KW - Progeny KW - Vaccines KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808691839?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Rock+Mechanics+and+Mining+Sciences&rft.atitle=Use+of+reservoir+simulation+and+in-mine+ventilation+measurements+to+estimate+coal+seam+properties&rft.au=Erdogan%2C+S+S%3BKaracan%2C+COe%3BOkandan%2C+E&rft.aulast=Erdogan&rft.aufirst=S&rft.date=2013-10-01&rft.volume=63&rft.issue=&rft.spage=148&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Rock+Mechanics+and+Mining+Sciences&rft.issn=13651609&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Number of references - 29 N1 - Last updated - 2016-09-01 N1 - SubjectsTermNotLitGenreText - Genomes; Serotypes; Data processing; Pediatrics; Drug resistance; Nucleotide sequence; penicillin-binding protein; Genotypes; Children; Mass spectroscopy; Combined vaccines; beta -Lactam antibiotics; Polymerase chain reaction; Progeny; Vaccines; Bacteria; Streptococcus pneumoniae DO - http://dx.doi.org/10.1016/j.cmi.2015.08.027 ER - TY - JOUR T1 - Investigation of HIV Incidence Rates in a High-Risk, High-Prevalence Kenyan Population AN - 1808685988; PQ0003418565 AB - Cost-effective HIV prevention programs should target persons at high risk of HIV acquisition. We conducted an observational HIV incidence cohort study in Kisumu, Kenya, where HIV prevalence is triple that of the national rate. We used referral and venue-sampling approaches to enroll HIV-negative persons for a 12-month observational cohort, August 2010 to September 2011, collected data using computer-assisted interviews, and performed HIV testing quarterly. Among 1292 eligible persons, 648 (50%) were excluded for HIV positivity and other reasons. Of the 644 enrollees, 52% were women who were significantly older than men (P < .01). In all, 7 persons seroconverted (incidence rate [IR] per 100 person-years = 1.11; 95% confidence interval [CI] 0.45-2.30), 6 were women; 5 (IR = 3.14; 95% CI 1.02-7.34) of whom were less than or equal to 25 years. Most new infections occurred in young women, an observation consistent with other findings in sub-Saharan Africa that women aged less than or equal to 25 years are an important population for HIV intervention trials in Africa. JF - Journal of the International Association of Providers of AIDS Care (JIAPAC) AU - Mdodo, Rennatus AU - Gust, Deborah AU - Otieno, Fredrick O AU - McLellan-Lemal, Eleanor AU - Chen, Robert T AU - LeBaron, Charles AU - Hardnett, Felicia AU - Turner, Kyle AU - Ndivo, Richard AU - Zeh, Clement AU - Samandari, Taraz AU - Mills, Lisa A AD - Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA, cax6@cdc.gov Y1 - 2016/01// PY - 2016 DA - January 2016 SP - 42 EP - 50 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU United Kingdom VL - 15 IS - 1 SN - 2325-9574, 2325-9574 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - clinical trials KW - HIV incidence KW - risk factors KW - Kenya KW - Acquired immune deficiency syndrome KW - Data processing KW - Intervention KW - Infection KW - Prevention KW - Human immunodeficiency virus KW - Kenya, Nyanza, Kisumu KW - Risk factors KW - Economics KW - Africa KW - Risk groups KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808685988?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+International+Association+of+Providers+of+AIDS+Care+%28JIAPAC%29&rft.atitle=Investigation+of+HIV+Incidence+Rates+in+a+High-Risk%2C+High-Prevalence+Kenyan+Population&rft.au=Mdodo%2C+Rennatus%3BGust%2C+Deborah%3BOtieno%2C+Fredrick+O%3BMcLellan-Lemal%2C+Eleanor%3BChen%2C+Robert+T%3BLeBaron%2C+Charles%3BHardnett%2C+Felicia%3BTurner%2C+Kyle%3BNdivo%2C+Richard%3BZeh%2C+Clement%3BSamandari%2C+Taraz%3BMills%2C+Lisa+A&rft.aulast=Mdodo&rft.aufirst=Rennatus&rft.date=2016-01-01&rft.volume=15&rft.issue=1&rft.spage=42&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+International+Association+of+Providers+of+AIDS+Care+%28JIAPAC%29&rft.issn=23259574&rft_id=info:doi/10.1177%2F2325957413511667 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-09-01 N1 - SubjectsTermNotLitGenreText - Data processing; Risk factors; Risk groups; Infection; Prevention; Acquired immune deficiency syndrome; Economics; Intervention; Human immunodeficiency virus; Kenya; Kenya, Nyanza, Kisumu; Africa DO - http://dx.doi.org/10.1177/2325957413511667 ER - TY - JOUR T1 - Analysis on the prevalence of malaria cases in Dalian from 2011-2014 AN - 1808676837; PQ0003354910 AB - Objective To analyze the epidemiological characteristics and laboratory test results of malaria cases reported in Dalian from 2011-2014,explore the current prevalence and trend of malaria,and provide references for malaria control strategy and monitoring means.Methods Microscopic examination,RDT and Nested-PCR were used to detect malaria cases.Nested-PCR was used for the identification of Plasmodium species.Epidemiological analysis was conducted.Results There were 50 cases of malaria reported and identified in Dalian from 2011 to 2014,with 12,16,10 and 12cases in 2011-2014 respectively.Four species of Plasmodia were detected,including P.falciparum,P.vivax,P.ovale and P.malariae,as well as an undetined Plasmodium,which accounted for 82.0%(41/50),6.0%(3/50),6.0%(3/50),2.0%(1/50)and 4.0%(2/50)respectively.All the cases were imported ones from Africa except one from Dandong and one from India.Construction workers(40.0%)and fishermen(34.0%)were the major infected populations.Conclusion The natural environment in Dalian is prone to the prevalence of plasmodium infection.It is very important to monitor the local and imported malaria cases in order to prevent malaria from transmission and prevalence. JF - Chinese Journal of Microecology AU - Chen, Yu-feng AU - Yu, Gang-yin AU - Hou, Jun AU - Xu, Dan AU - Zheng, Li-li AU - Ren, Yi-xin AU - Qin, Yuan-hua AU - Wang, Xiao-wei AU - Cui, Yu AD - Dalian Center for Disease Control and Prevention Y1 - 2016///0, PY - 2016 DA - 0, 2016 SP - 601 EP - 605 PB - Editorial Department of Chinese Journal of Microecology, 465 Zhongshan Road Dalian 116027 China VL - 28 IS - 5 SN - 1005-376X, 1005-376X KW - Microbiology Abstracts A: Industrial & Applied Microbiology; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Malaria KW - epidemiology KW - laboratory test KW - Biological surveys KW - China, People's Rep., Liaoning Prov., Dandong KW - Human diseases KW - Disease transmission KW - Public health KW - Plasmodium KW - Tests KW - Africa KW - China, People's Rep., Liaoning Prov., Dalian KW - Plasmodia KW - K 03400:Human Diseases KW - Q1 08485:Species interactions: pests and control KW - Q5 08524:Public health, medicines, dangerous organisms KW - A 01300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808676837?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chinese+Journal+of+Microecology&rft.atitle=Analysis+on+the+prevalence+of+malaria+cases+in+Dalian+from+2011-2014&rft.au=Chen%2C+Yu-feng%3BYu%2C+Gang-yin%3BHou%2C+Jun%3BXu%2C+Dan%3BZheng%2C+Li-li%3BRen%2C+Yi-xin%3BQin%2C+Yuan-hua%3BWang%2C+Xiao-wei%3BCui%2C+Yu&rft.aulast=Chen&rft.aufirst=Yu-feng&rft.date=2016-01-01&rft.volume=28&rft.issue=5&rft.spage=601&rft.isbn=&rft.btitle=&rft.title=Chinese+Journal+of+Microecology&rft.issn=1005376X&rft_id=info:doi/ LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Biological surveys; Human diseases; Tests; Malaria; Public health; Plasmodia; Disease transmission; Plasmodium; China, People's Rep., Liaoning Prov., Dandong; Africa; China, People's Rep., Liaoning Prov., Dalian ER - TY - JOUR T1 - Malaria Parasitemia among Febrile Patients Seeking Clinical Care at an Outpatient Health Facility in an Urban Informal Settlement Area in Nairobi, Kenya AN - 1765975470; PQ0002580207 AB - Nairobi is considered a low-risk area for malaria transmission, but travel can influence transmission of malaria. We investigated the demographic characteristics and travel history of patients with documented fever and malaria in a study clinic in a population-based surveillance system over a 5-year period, January 1, 2007 to December 31, 2011. During the study period, 11,480 (68%) febrile patients had a microscopy test performed for malaria, of which 2,553 (22%) were positive. Malaria was detected year-round with peaks in January, May, and September. Children aged 5-14 years had the highest proportion (28%) of positive results followed by children aged 1-4 years (23%). Almost two-thirds of patients with malaria reported traveling outside Nairobi; 79% of these traveled to three counties in western Kenya. History of recent travel (i.e., in past month) was associated with malaria parasitemia (odds ratio: 10.0, 95% confidence interval: 9.0-11.0). Malaria parasitemia was frequently observed among febrile patients at a health facility in the urban slum of Kibera, Nairobi. The majority of patients had traveled to western Kenya. However, 34% reported no travel history, which raises the possibility of local malaria transmission in this densely populated, urban setting. These findings have important implications for malaria control in large Nairobi settlements. JF - American Journal of Tropical Medicine and Hygiene AU - Njuguna, Henry N AU - Montgomery, Joel M AU - Cosmas, Leonard AU - Wamola, Newton AU - Oundo, Joseph O AU - Desai, Meghna AU - Buff, Ann M AU - Breiman, Robert F AD - Kenya Medical Research Institute (KEMRI), Nairobi, Kenya, hnjuguna@cdc.gov Y1 - 2016/01// PY - 2016 DA - January 2016 SP - 122 EP - 127 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 94 IS - 1 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts KW - Travel KW - Historical account KW - Human diseases KW - Population density KW - Malaria KW - Disease transmission KW - Public health KW - Demography KW - Fever KW - Risk groups KW - Slums KW - Urban areas KW - Biological surveys KW - Kenya, Nairobi KW - Children KW - parasitemia KW - Microscopy KW - Hygiene KW - K 03400:Human Diseases KW - Q1 08604:Stock assessment and management KW - Q5 08524:Public health, medicines, dangerous organisms KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1765975470?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Malaria+Parasitemia+among+Febrile+Patients+Seeking+Clinical+Care+at+an+Outpatient+Health+Facility+in+an+Urban+Informal+Settlement+Area+in+Nairobi%2C+Kenya&rft.au=Njuguna%2C+Henry+N%3BMontgomery%2C+Joel+M%3BCosmas%2C+Leonard%3BWamola%2C+Newton%3BOundo%2C+Joseph+O%3BDesai%2C+Meghna%3BBuff%2C+Ann+M%3BBreiman%2C+Robert+F&rft.aulast=Njuguna&rft.aufirst=Henry&rft.date=2016-01-01&rft.volume=119&rft.issue=7&rft.spage=1023&rft.isbn=&rft.btitle=&rft.title=Environmental+health+perspectives&rft.issn=1552-9924&rft_id=info:doi/10.1289%2Fehp.1002725 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Biological surveys; Human diseases; Malaria; Hygiene; Public health; Fever; Demography; Travel; parasitemia; Microscopy; Risk groups; Children; Historical account; Population density; Slums; Urban areas; Disease transmission; Kenya, Nairobi DO - http://dx.doi.org/10.4269/ajtmh.15-0293 ER - TY - JOUR T1 - Epidemiology of Invasive Group A Streptococcal Disease in Alaska, 2001 to 2013 AN - 1762381002; PQ0002453139 AB - The Arctic Investigations Program (AIP) began surveillance for invasive group A streptococcal (GAS) infections in Alaska in 2000 as part of the invasive bacterial diseases population-based laboratory surveillance program. Between 2001 and 2013, there were 516 cases of GAS infection reported, for an overall annual incidence of 5.8 cases per 100,000 persons with 56 deaths (case fatality rate, 10.7%). Of the 516 confirmed cases of invasive GAS infection, 422 (82%) had isolates available for laboratory analysis. All isolates were susceptible to penicillin, cefotaxime, and levofloxacin. Resistance to tetracycline, erythromycin, and clindamycin was seen in 11% (n = 8), 5.8% (n = 20), and 1.2% (n = 4) of the isolates, respectively. A total of 51 emm types were identified, of which emm1 (11.1%) was the most prevalent, followed by emm82 (8.8%), emm49 (7.8%), emm12 and emm3 (6.6% each), emm89 (6.2%), emm108 (5.5%), emm28 (4.7%), emm92 (4%), and emm41 (3.8%). The five most common emm types accounted for 41% of isolates. The emm types in the proposed 26-valent and 30-valent vaccines accounted for 56% and 78% of all cases, respectively. GAS remains an important cause of invasive bacterial disease in Alaska. Continued surveillance of GAS infections will help improve understanding of the epidemiology of invasive disease, with an impact on disease control, notification of outbreaks, and vaccine development. JF - Journal of Clinical Microbiology AU - Rudolph, Karen AU - Bruce, Michael G AU - Bruden, Dana AU - Zulz, Tammy AU - Reasonover, Alisa AU - Hurlburt, Debby AU - Hennessy, Thomas Y1 - 2016/01// PY - 2016 DA - January 2016 SP - 134 EP - 141 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 54 IS - 1 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Streptococcus KW - Clindamycin KW - Cefotaxime KW - Epidemiology KW - Levofloxacin KW - Disease control KW - Vaccines KW - Infection KW - Tetracyclines KW - Erythromycin KW - Penicillin KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1762381002?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Epidemiology+of+Invasive+Group+A+Streptococcal+Disease+in+Alaska%2C+2001+to+2013&rft.au=Rudolph%2C+Karen%3BBruce%2C+Michael+G%3BBruden%2C+Dana%3BZulz%2C+Tammy%3BReasonover%2C+Alisa%3BHurlburt%2C+Debby%3BHennessy%2C+Thomas&rft.aulast=Rudolph&rft.aufirst=Karen&rft.date=2016-01-01&rft.volume=54&rft.issue=1&rft.spage=134&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.02122-15 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Number of references - 46 N1 - Last updated - 2016-07-20 N1 - SubjectsTermNotLitGenreText - Clindamycin; Cefotaxime; Epidemiology; Levofloxacin; Disease control; Vaccines; Erythromycin; Tetracyclines; Infection; Penicillin; Streptococcus DO - http://dx.doi.org/10.1128/JCM.02122-15 ER - TY - JOUR T1 - The utility of population-based surveys to describe the continuum of HIV services for key and general populations AN - 1762377821; PQ0002525285 AB - Monitoring the cascade or continuum of HIV services - ranging from outreach services to anti-retroviral treatment - has become increasingly important as the focus in prevention moves toward biomedical interventions, in particular, 'Treatment as Prevention.' The HIV continuum typically utilises clinic-based care and treatment monitoring data and helps identify gaps and inform programme improvements. This paper discusses the merits of a population-based survey-informed continuum of services. Surveys provide individual-level, population-based data by sampling persons both in and outside the continuum, which facilitate the estimation of population fractions, such as the proportion of people living with HIV in care, as well as the examination of determinants for being in or outside the continuum. Survey-informed cascades of services may especially benefit key populations at increased risk for HIV infection for who social marginalisation, criminalisation, and stigma result in barriers to access and retention in services, a low social visibility, mobility, and outreach-based services can compromise clinic-based monitoring. Adding CD4+ T-cell count and viral load measurements to such surveys may provide population-level information on viral load suppression, stage of disease, treatment needs, and population-level transmission potential. While routine clinic-based reporting will remain the mainstay of monitoring, a survey-informed service cascade can address some of its limitations and offer additional insights. JF - International Journal of STD & AIDS AU - Hladik, Wolfgang AU - Benech, Irene AU - Bateganya, Moses AU - Hakim, Avi J Y1 - 2016/01// PY - 2016 DA - January 2016 SP - 5 EP - 12 PB - Sage Publications, Inc., 2455 Teller Road Thousand Oaks CA 91320 United States VL - 27 IS - 1 SN - 0956-4624, 0956-4624 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Continuum of HIV services KW - cascade of services KW - care and treatment KW - population-based surveys KW - key populations KW - HIV KW - AIDS KW - treatment KW - antiretroviral therapy KW - Acquired immune deficiency syndrome KW - Data processing KW - Mobility KW - Intervention KW - Infection KW - Stigma KW - Health risks KW - Prevention KW - CD4 antigen KW - Human immunodeficiency virus KW - Lymphocytes T KW - Visibility KW - Sampling KW - Sexually transmitted diseases KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1762377821?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+STD+%26+AIDS&rft.atitle=The+utility+of+population-based+surveys+to+describe+the+continuum+of+HIV+services+for+key+and+general+populations&rft.au=Hladik%2C+Wolfgang%3BBenech%2C+Irene%3BBateganya%2C+Moses%3BHakim%2C+Avi+J&rft.aulast=Hladik&rft.aufirst=Wolfgang&rft.date=2016-01-01&rft.volume=16&rft.issue=3&rft.spage=2391&rft.isbn=&rft.btitle=&rft.title=Molecules+%28Basel%2C+Switzerland%29&rft.issn=1420-3049&rft_id=info:doi/10.3390%2Fmolecules16032391 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Number of references - 45 N1 - Last updated - 2016-02-29 N1 - SubjectsTermNotLitGenreText - CD4 antigen; Data processing; Mobility; Lymphocytes T; Sampling; Infection; Stigma; Health risks; Acquired immune deficiency syndrome; Prevention; Human immunodeficiency virus; Intervention; Visibility; Sexually transmitted diseases DO - http://dx.doi.org/10.1177/0956462415581728 ER - TY - JOUR T1 - Prior infection with influenza virus but not vaccination leaves a long-term immunological imprint that intensifies the protective efficacy of antigenically drifted vaccine strains AN - 1762377708; PQ0002518801 AB - The role of pre-existing immunity for influenza vaccine responses is of great importance for public health, and thus has been studied in various contexts, yet the impact of differential priming on vaccine responses in the midst of antigenic drift remains to be elucidated. To address this with antigenically related viruses, mice were first primed by either infection or immunization with A/Puerto Rico/8/34 (PR8) virus, then immunized with whole-inactivated A/Fort Monmouth/1/47 (FM1) virus. The ensuing vaccine responses and the protective efficacy of FM1 were superior in PR8 infection-primed mice compared to PR8 immunization-primed or unprimed mice. Increased FM1-specific Ab responses of PR8 infection-primed mice also broadened cross-reactivity against contemporary as well as antigenically more drifted strains. Further, prior infection heightened the protective efficacy of antigenically distant strains, such as A/Brisbane/59/2006 infection followed by immunization with split pandemic H1N1 vaccine (A/California/07/2009). Therefore, influenza infection is a significant priming event that intensifies future vaccine responses against drift strains. JF - Vaccine AU - Kim, Jin Hyang AU - Liepkalns, Justine AU - Reber, Adrian J AU - Lu, Xiuhua AU - Music, Nedzad AU - Jacob, Joshy AU - Sambhara, Suryaprakash AD - Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30329, USA Y1 - 2016/01// PY - 2016 DA - January 2016 SP - 495 EP - 502 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 34 IS - 4 SN - 0264-410X, 0264-410X KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts; Immunology Abstracts KW - HA hemagglutinin KW - NA neuraminidase KW - HI hemagglutination inhibition KW - HAU hemagglutination unit KW - MN microneutralization KW - LD50 50% lethal dose KW - PFU plaque forming unit KW - Influenza virus KW - Infection KW - Antigenic drift KW - Vaccine efficacy KW - Pandemic H1N1 KW - Cross-reactivity KW - Viruses KW - Leaves KW - Mice KW - Immunity KW - Vaccination KW - Immunization KW - Public health KW - Influenza KW - Antibodies KW - pandemics KW - ASW, Caribbean Sea, Greater Antilles, Puerto Rico KW - Drift KW - INE, USA, California KW - Vaccines KW - Australia, Queensland, Brisbane KW - V 22350:Immunology KW - F 06905:Vaccines KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1762377708?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Prior+infection+with+influenza+virus+but+not+vaccination+leaves+a+long-term+immunological+imprint+that+intensifies+the+protective+efficacy+of+antigenically+drifted+vaccine+strains&rft.au=Kim%2C+Jin+Hyang%3BLiepkalns%2C+Justine%3BReber%2C+Adrian+J%3BLu%2C+Xiuhua%3BMusic%2C+Nedzad%3BJacob%2C+Joshy%3BSambhara%2C+Suryaprakash&rft.aulast=Kim&rft.aufirst=Jin&rft.date=2016-01-01&rft.volume=93&rft.issue=6&rft.spage=1311&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.15-0467 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Number of references - 35 N1 - Last updated - 2016-08-03 N1 - SubjectsTermNotLitGenreText - Influenza; pandemics; Antibodies; Antigenic drift; Cross-reactivity; Drift; Leaves; Immunity; Vaccines; Infection; Vaccination; Public health; Viruses; Mice; Immunization; Influenza virus; ASW, Caribbean Sea, Greater Antilles, Puerto Rico; INE, USA, California; Australia, Queensland, Brisbane DO - http://dx.doi.org/10.1016/j.vaccine.2015.11.077 ER - TY - JOUR T1 - The lipid moiety of brincidofovir is required for in vitro antiviral activity against Ebola virus AN - 1762373859; PQ0002487443 AB - Brincidofovir (BCV) is the 3-hexadecyloxy-1-propanol (HDP) lipid conjugate of the acyclic nucleoside phosphonate cidofovir (CDV). BCV has established broad-spectrum activity against double-stranded DNA (dsDNA) viruses; however, its activity against RNA viruses has been less thoroughly evaluated. Here, we report that BCV inhibited infection of Ebola virus in multiple human cell lines. Unlike the mechanism of action for BCV against cytomegalovirus and other dsDNA viruses, phosphorylation of CDV to the diphosphate form appeared unnecessary. Instead, antiviral activity required the lipid moiety and in vitro activity against EBOV was observed for several HDP-nucleotide conjugates. JF - Antiviral Research AU - McMullan, Laura K AU - Flint, Mike AU - Dyall, Julie AU - Albarino, Cesar AU - Olinger, Gene G AU - Foster, Scott AU - Sethna, Phiroze AU - Hensley, Lisa E AU - Nichol, Stuart T AU - Lanier, ERandall AU - Spiropoulou, Christina F AD - Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USA Y1 - 2016/01// PY - 2016 DA - January 2016 SP - 71 EP - 78 PB - Elsevier B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 125 SN - 0166-3542, 0166-3542 KW - Virology & AIDS Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Ebola KW - Antiviral therapy KW - In vitro screen KW - Brincidofovir KW - Cidofovir KW - phosphonates KW - Phosphorylation KW - Lipids KW - nucleosides KW - Ebola virus KW - RNA viruses KW - Antiviral activity KW - Infection KW - Cytomegalovirus KW - DNA viruses KW - A 01340:Antibiotics & Antimicrobials KW - V 22340:Antiviral Agents UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1762373859?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Trends+in+Disease+and+Complications+of+Hepatitis+A+Virus+Infection+in+the+United+States%2C+1999-2011%3A+A+New+Concern+for+Adults&rft.au=Ly%2C+Kathleen+N%3BKlevens%2C+R+Monina&rft.aulast=Ly&rft.aufirst=Kathleen&rft.date=2015-07-15&rft.volume=212&rft.issue=2&rft.spage=176&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiu834 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Last updated - 2016-02-29 N1 - SubjectsTermNotLitGenreText - Cidofovir; phosphonates; Phosphorylation; Lipids; nucleosides; RNA viruses; Infection; Antiviral activity; DNA viruses; Ebola virus; Cytomegalovirus DO - http://dx.doi.org/10.1016/j.antiviral.2015.10.010 ER - TY - JOUR T1 - The CDC Injury Center's Response to the Growing Public Health Problem of Falls Among Older Adults AN - 1762364501; PQ0002485909 AB - Background . Older adult falls are a significant cause of morbidity and mortality in the United States. This leading cause of injury in adults aged 65 and older results in $35 billion in direct medical costs. Objective. To project the number of older adult falls by 2030 and the associated lifetime medical cost. A secondary objective is to review what clinicians can do to incorporate falls screening and prevention into their practice for community-dwelling older adults. Methods . Using the Centers for Disease Control and Prevention's Web-based Injury Statistics Query and Reporting System and the US Census Bureau data, the number of older adults in 2030, fatal falls, and medical costs associated with fall injuries was projected. In addition, evidence-based interventions that can be integrated into clinical practice were reviewed. Results . The number of older adult fatal falls is projected to reach 100000 per year by 2030 with an associated cost of $100 billion. By integrating screening for falls risk into clinical practice, reviewing and modifying medications, and recommending vitamin D supplementation, physicians can reduce future falls by nearly 25%. Conclusion . Falls in older adults will continue to rise substantially and become a significant cost to our health care system if we do not begin to focus on prevention in the clinical setting. JF - American Journal of Lifestyle Medicine AU - Houry, Debra AU - Florence, Curtis AU - Baldwin, Grant AU - Stevens, Judy AU - McClure, Rod AD - National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia, Vjz7@cdc.gov Y1 - 2016/01// PY - 2016 DA - January 2016 SP - 74 EP - 77 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU United Kingdom VL - 10 IS - 1 SN - 1559-8276, 1559-8276 KW - Health & Safety Science Abstracts KW - falls KW - prevention KW - older adults KW - STEADI KW - Mortality KW - Injuries KW - Disease control KW - Intervention KW - Morbidity KW - Public health KW - USA KW - Prevention KW - Vitamin D KW - Health care KW - Reviews KW - Census KW - Drugs KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1762364501?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Lifestyle+Medicine&rft.atitle=The+CDC+Injury+Center%27s+Response+to+the+Growing+Public+Health+Problem+of+Falls+Among+Older+Adults&rft.au=Houry%2C+Debra%3BFlorence%2C+Curtis%3BBaldwin%2C+Grant%3BStevens%2C+Judy%3BMcClure%2C+Rod&rft.aulast=Houry&rft.aufirst=Debra&rft.date=2016-01-01&rft.volume=10&rft.issue=1&rft.spage=74&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Lifestyle+Medicine&rft.issn=15598276&rft_id=info:doi/10.1177%2F1559827615600137 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Number of references - 22 N1 - Last updated - 2016-02-29 N1 - SubjectsTermNotLitGenreText - Mortality; Prevention; Vitamin D; Health care; Injuries; Reviews; Disease control; Intervention; Census; Drugs; Morbidity; Public health; USA DO - http://dx.doi.org/10.1177/1559827615600137 ER - TY - JOUR T1 - Characterization of Bacterial Communities in Selected Smokeless Tobacco Products Using 16S rDNA Analysis. AN - 1760886079; 26784944 AB - The bacterial communities present in smokeless tobacco (ST) products have not previously reported. In this study, we used Next Generation Sequencing to study the bacteria present in U.S.-made dry snuff, moist snuff and Sudanese toombak. Sample diversity and taxonomic abundances were investigated in these products. A total of 33 bacterial families from four phyla, Actinobacteria, Firmicutes, Proteobacteria and Bacteroidetes, were identified. U.S.-produced dry snuff products contained a diverse distribution of all four phyla. Moist snuff products were dominated by Firmicutes. Toombak samples contained mainly Actinobacteria and Firmicutes (Aerococcaceae, Enterococcaceae, and Staphylococcaceae). The program PICRUSt (Phylogenetic Investigation of Communities by Reconstruction of Unobserved States) was used to impute the prevalence of genes encoding selected bacterial toxins, antibiotic resistance genes and other pro-inflammatory molecules. PICRUSt also predicted the presence of specific nitrate reductase genes, whose products can contribute to the formation of carcinogenic nitrosamines. Characterization of microbial community abundances and their associated genomes gives us an indication of the presence or absence of pathways of interest and can be used as a foundation for further investigation into the unique microbiological and chemical environments of smokeless tobacco products. JF - PloS one AU - Tyx, Robert E AU - Stanfill, Stephen B AU - Keong, Lisa M AU - Rivera, Angel J AU - Satten, Glen A AU - Watson, Clifford H AD - Division of Laboratory Sciences at the Centers for Disease Control and Prevention, Atlanta, GA, United States of America. ; Division of Reproductive Health, Center for Disease Control and Prevention, Atlanta, GA, United States of America. Y1 - 2016 PY - 2016 DA - 2016 SP - 1 VL - 11 IS - 1 KW - Bacterial Toxins KW - 0 KW - DNA, Bacterial KW - DNA, Ribosomal KW - RNA, Ribosomal, 16S KW - Index Medicus KW - United States KW - Phylogeny KW - Bacterial Toxins -- genetics KW - Software KW - Drug Resistance, Bacterial KW - Metagenome KW - High-Throughput Nucleotide Sequencing KW - Bacteria -- genetics KW - RNA, Ribosomal, 16S -- analysis KW - Tobacco, Smokeless -- classification KW - Bacteria -- classification KW - DNA, Ribosomal -- analysis KW - DNA, Bacterial -- analysis KW - Tobacco, Smokeless -- microbiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1760886079?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=PloS+one&rft.atitle=Characterization+of+Bacterial+Communities+in+Selected+Smokeless+Tobacco+Products+Using+16S+rDNA+Analysis.&rft.au=Tyx%2C+Robert+E%3BStanfill%2C+Stephen+B%3BKeong%2C+Lisa+M%3BRivera%2C+Angel+J%3BSatten%2C+Glen+A%3BWatson%2C+Clifford+H&rft.aulast=Tyx&rft.aufirst=Robert&rft.date=2016-01-01&rft.volume=11&rft.issue=1&rft.spage=e0146939&rft.isbn=&rft.btitle=&rft.title=PloS+one&rft.issn=1932-6203&rft_id=info:doi/10.1371%2Fjournal.pone.0146939 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2016-07-28 N1 - Date created - 2016-01-20 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Cited By: J Bacteriol. 1999 Nov;181(21):6573-84 [10542156] Nature. 2013 May 30;497(7451):647-51 [23665960] J Bacteriol. 2002 Mar;184(5):1314-23 [11844760] Clin Diagn Lab Immunol. 2002 Sep;9(5):1057-60 [12204959] J Bacteriol. 2003 Dec;185(24):7247-56 [14645286] Carcinogenesis. 1991 Jun;12(6):1115-8 [2044192] Mol Microbiol. 1994 May;12(4):579-86 [7934881] Arch Microbiol. 1996 Dec;166(6):361-7 [9082911] Nucleic Acids Res. 1999 Jan 1;27(1):29-34 [9847135] Oral Oncol. 1998 Nov;34(6):558-66 [9930371] Nucleic Acids Res. 2014 Jan;42(Database issue):D199-205 [24214961] Nucleic Acids Res. 2014 Jan;42(Database issue):D643-8 [24293649] Int J Food Microbiol. 2015 Nov 6;212:60-6 [25805616] J Agric Food Chem. 2015 Oct 21;63(41):9131-8 [26452144] J Bacteriol. 1999 Jun;181(12):3658-65 [10368138] Appl Environ Microbiol. 2007 Feb;73(3):825-37 [17142368] Appl Microbiol Biotechnol. 2007 Jun;75(3):633-45 [17318539] Appl Microbiol Biotechnol. 2007 Jun;75(4):889-97 [17347820] Nucleic Acids Res. 2007;35(21):7188-96 [17947321] Nicotine Tob Res. 2008 Nov;10(11):1645-52 [18988077] Nicotine Tob Res. 2008 Dec;10(12):1773-82 [19023828] Regul Toxicol Pharmacol. 2009 Mar;53(2):121-33 [19135498] Environ Health Perspect. 2010 Mar;118(3):351-6 [20064769] Int J Syst Evol Microbiol. 2010 Apr;60(Pt 4):874-9 [19661509] Nat Methods. 2010 May;7(5):335-6 [20383131] Appl Microbiol Biotechnol. 2010 Sep;88(2):553-62 [20645083] Tob Control. 2011 May;20(3):e2 [21109685] Nucleic Acids Res. 2000 Jan 1;28(1):27-30 [10592173] Appl Microbiol Biotechnol. 2011 Dec;92(5):1033-44 [21660545] Biochem Soc Trans. 2011 Dec;39(6):1838-43 [22103536] Nucleic Acids Res. 2012 Jan;40(Database issue):D115-22 [22194640] Food Chem Toxicol. 2012 Mar;50(3-4):942-8 [22142690] PLoS One. 2012;7(5):e36357 [22563494] Tob Control. 2012 Jul;21(4):396-401 [21642445] Regul Toxicol Pharmacol. 2012 Dec;64(3):367-87 [23000415] Nucleic Acids Res. 2013 Jan;41(Database issue):D590-6 [23193283] Nucleic Acids Res. 2013 Jan 7;41(1):e1 [22933715] Food Chem Toxicol. 2013 Jul;57:380-6 [23517910] Nat Biotechnol. 2013 Sep;31(9):814-21 [23975157] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1371/journal.pone.0146939 ER - TY - JOUR T1 - Increases in Drug and Opioid Overdose Deaths--United States, 2000-2014. AN - 1753007256; 26720857 AB - The United States is experiencing an epidemic of drug overdose (poisoning) deaths. Since 2000, the rate of deaths from drug overdoses has increased 137%, including a 200% increase in the rate of overdose deaths involving opioids (opioid pain relievers and heroin). CDC analyzed recent multiple cause-of-death mortality data to examine current trends and characteristics of drug overdose deaths, including the types of opioids associated with drug overdose deaths. During 2014, a total of 47,055 drug overdose deaths occurred in the United States, representing a 1-year increase of 6.5%, from 13.8 per 100,000 persons in 2013 to 14.7 per 100,000 persons in 2014. The rate of drug overdose deaths increased significantly for both sexes, persons aged 25-44 years and ≥55 years, non-Hispanic whites and non-Hispanic blacks, and in the Northeastern, Midwestern, and Southern regions of the United States. Rates of opioid overdose deaths also increased significantly, from 7.9 per 100,000 in 2013 to 9.0 per 100,000 in 2014, a 14% increase. Historically, CDC has programmatically characterized all opioid pain reliever deaths (natural and semisynthetic opioids, methadone, and other synthetic opioids) as "prescription" opioid overdoses (1). Between 2013 and 2014, the age-adjusted rate of death involving methadone remained unchanged; however, the age-adjusted rate of death involving natural and semisynthetic opioid pain relievers, heroin, and synthetic opioids, other than methadone (e.g., fentanyl) increased 9%, 26%, and 80%, respectively. The sharp increase in deaths involving synthetic opioids, other than methadone, in 2014 coincided with law enforcement reports of increased availability of illicitly manufactured fentanyl, a synthetic opioid; however, illicitly manufactured fentanyl cannot be distinguished from prescription fentanyl in death certificate data. These findings indicate that the opioid overdose epidemic is worsening. There is a need for continued action to prevent opioid abuse, dependence, and death, improve treatment capacity for opioid use disorders, and reduce the supply of illicit opioids, particularly heroin and illicit fentanyl. JF - MMWR. Morbidity and mortality weekly report AU - Rudd, Rose A AU - Aleshire, Noah AU - Zibbell, Jon E AU - Gladden, R Matthew AD - Division of Unintentional Injury Prevention, National Center for Injury Prevention and Control, CDC. Y1 - 2016/01/01/ PY - 2016 DA - 2016 Jan 01 SP - 1378 EP - 1382 VL - 64 IS - 50-51 KW - Analgesics, Opioid KW - 0 KW - Index Medicus KW - Infant KW - Young Adult KW - Humans KW - Adult KW - Infant, Newborn KW - Aged KW - Middle Aged KW - Child KW - Adolescent KW - United States -- epidemiology KW - Male KW - Female KW - Child, Preschool KW - Analgesics, Opioid -- poisoning KW - Drug Overdose -- mortality UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1753007256?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=MMWR.+Morbidity+and+mortality+weekly+report&rft.atitle=Increases+in+Drug+and+Opioid+Overdose+Deaths--United+States%2C+2000-2014.&rft.au=Rudd%2C+Rose+A%3BAleshire%2C+Noah%3BZibbell%2C+Jon+E%3BGladden%2C+R+Matthew&rft.aulast=Rudd&rft.aufirst=Rose&rft.date=2016-01-01&rft.volume=64&rft.issue=50-51&rft.spage=1378&rft.isbn=&rft.btitle=&rft.title=MMWR.+Morbidity+and+mortality+weekly+report&rft.issn=1545-861X&rft_id=info:doi/10.15585%2Fmmwr.mm6450a3 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2016-04-26 N1 - Date created - 2016-01-01 N1 - Date revised - 2017-01-14 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.15585/mmwr.mm6450a3 ER - TY - JOUR T1 - Communitywide cryptosporidiosis outbreak associated with a surface water-supplied municipal water system - Baker City, Oregon, 2013 AN - 1751229127; PQ0002409331 AB - Cryptosporidium, a parasite known to cause large drinking and recreational water outbreaks, is tolerant of chlorine concentrations used for drinking water treatment. Human laboratory-based surveillance for enteric pathogens detected a cryptosporidiosis outbreak in Baker City, Oregon during July 2013 associated with municipal drinking water. Objectives of the investigation were to confirm the outbreak source and assess outbreak extent. The watershed was inspected and city water was tested for contamination. To determine the community attack rate, a standardized questionnaire was administered to randomly sampled households. Weighted attack rates and confidence intervals (CIs) were calculated. Water samples tested positive for Cryptosporidium species; a Cryptosporidium parvum subtype common in cattle was detected in human stool specimens. Cattle were observed grazing along watershed borders; cattle faeces were observed within watershed barriers. The city water treatment facility chlorinated, but did not filter, water. The community attack rate was 28.3% (95% CI 22.1-33.6), sickening an estimated 2780 persons. Watershed contamination by cattle probably caused this outbreak; water treatments effective against Cryptosporidium were not in place. This outbreak highlights vulnerability of drinking water systems to pathogen contamination and underscores the need for communities to invest in system improvements to maintain multiple barriers to drinking water contamination. JF - Epidemiology and Infection AU - DeSILVA, M B AU - Schafer, S AU - Kendall Scott, M AU - Robinson, B AU - Hills, A AU - Buser, G L AU - Salis, K AU - Gargano, J AU - Yoder, J AU - Hill, V AU - Xiao, L AU - Roellig, D AU - Hedberg, K AD - Epidemic Intelligence Service, Division of Scientific Education and Professional Development, Center for Surveillance, Epidemiology, and Laboratory Services, CDC, Atlanta, GA, USA, xdh8@cdc.gov Y1 - 2016/01// PY - 2016 DA - January 2016 SP - 274 EP - 284 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 144 IS - 2 SN - 0950-2688, 0950-2688 KW - Health & Safety Science Abstracts KW - Water sampling KW - Grazing KW - Pathogens KW - Watersheds KW - Cryptosporidium parvum KW - INE, USA, Oregon KW - Cryptosporidiosis KW - Cattle KW - Water treatment KW - Households KW - Water-borne diseases KW - Standards KW - Vulnerability KW - Outbreaks KW - Drinking water KW - Urban areas KW - H 3000:Environment and Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1751229127?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Communitywide+cryptosporidiosis+outbreak+associated+with+a+surface+water-supplied+municipal+water+system+-+Baker+City%2C+Oregon%2C+2013&rft.au=DeSILVA%2C+M+B%3BSchafer%2C+S%3BKendall+Scott%2C+M%3BRobinson%2C+B%3BHills%2C+A%3BBuser%2C+G+L%3BSalis%2C+K%3BGargano%2C+J%3BYoder%2C+J%3BHill%2C+V%3BXiao%2C+L%3BRoellig%2C+D%3BHedberg%2C+K&rft.aulast=DeSILVA&rft.aufirst=M&rft.date=2016-01-01&rft.volume=144&rft.issue=2&rft.spage=274&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268815001831 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-12-01 N1 - Number of references - 34 N1 - Last updated - 2016-03-30 N1 - SubjectsTermNotLitGenreText - Water sampling; Grazing; Pathogens; Watersheds; Cattle; Cryptosporidiosis; Water treatment; Households; Water-borne diseases; Standards; Outbreaks; Vulnerability; Drinking water; Urban areas; Cryptosporidium parvum; INE, USA, Oregon DO - http://dx.doi.org/10.1017/S0950268815001831 ER - TY - JOUR T1 - A case-control study of risk factors for death from 2009 pandemic influenza A(H1N1): is American Indian racial status an independent risk factor? AN - 1751228821; PQ0002409324 AB - Historically, American Indian/Alaska Native (AI/AN) populations have suffered excess morbidity and mortality from influenza. We investigated the risk factors for death from 2009 pandemic influenza A(H1N1) in persons residing in five states with substantial AI/AN populations. We conducted a case-control investigation using pandemic influenza fatalities from 2009 in Alaska, Arizona, New Mexico, Oklahoma and Wyoming. Controls were outpatients with influenza. We reviewed medical records and interviewed case proxies and controls. We used multiple imputation to predict missing data and multivariable conditional logistic regression to determine risk factors. We included 145 fatal cases and 236 controls; 22% of cases were AI/AN. Risk factors (P 45 years vs. <18 years], pre-existing medical conditions (mOR 7.1), smoking (mOR 3.0), delayed receipt of antivirals (mOR 6.5), and barriers to healthcare access (mOR 5.3). AI/AN race was not significantly associated with death. The increased influenza mortality in AI/AN individuals was due to factors other than racial status. Prevention of influenza deaths should focus on modifiable factors (smoking, early antiviral use, access to care) and identifying high-risk persons for immunization and prompt medical attention. JF - Epidemiology and Infection AU - Hennessy, T W AU - BRUDEN, D AU - Castrodale, L AU - Komatsu, K AU - Erhart, L M AU - Thompson, D AU - Bradley, K AU - O'Leary AU - McLAUGHLIN, J AU - Landen, M AD - Arctic Investigations Program, US Centers for Disease Control and Prevention (CDC), Anchorage, AK, USA, Tbh0@cdc.gov Y1 - 2016/01// PY - 2016 DA - January 2016 SP - 315 EP - 324 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 144 IS - 2 SN - 0950-2688, 0950-2688 KW - Virology & AIDS Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - Historical account KW - Age KW - Morbidity KW - USA, Oklahoma KW - Influenza KW - Smoking KW - pandemics KW - Risk factors KW - Geriatrics KW - Risk groups KW - Ethnic groups KW - Races KW - Mortality KW - USA, New Mexico KW - USA, Wyoming KW - Data processing KW - medical records KW - INE, USA, Alaska KW - Immunization KW - Prevention KW - Health care KW - Reviews KW - USA, Arizona KW - R2 23060:Medical and environmental health KW - H 12000:Epidemiology and Public Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1751228821?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=A+case-control+study+of+risk+factors+for+death+from+2009+pandemic+influenza+A%28H1N1%29%3A+is+American+Indian+racial+status+an+independent+risk+factor%3F&rft.au=Hennessy%2C+T+W%3BBRUDEN%2C+D%3BCastrodale%2C+L%3BKomatsu%2C+K%3BErhart%2C+L+M%3BThompson%2C+D%3BBradley%2C+K%3BO%27Leary%3BMcLAUGHLIN%2C+J%3BLanden%2C+M&rft.aulast=Hennessy&rft.aufirst=T&rft.date=2016-01-01&rft.volume=144&rft.issue=2&rft.spage=315&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268815001211 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-12-01 N1 - Number of references - 32 N1 - Last updated - 2016-03-30 N1 - SubjectsTermNotLitGenreText - Mortality; Data processing; medical records; Morbidity; Immunization; Influenza; Smoking; pandemics; Risk factors; Reviews; Geriatrics; Risk groups; Races; Historical account; Age; Prevention; Health care; Ethnic groups; USA, Oklahoma; USA, New Mexico; USA, Wyoming; USA, Arizona; INE, USA, Alaska DO - http://dx.doi.org/10.1017/S0950268815001211 ER - TY - JOUR T1 - Evaluating the effectiveness of state specific lead-based paint hazard risk reduction laws in preventing recurring incidences of lead poisoning in children. AN - 1735330787; 26472219 AB - Despite significant progress made in recent decades in preventing childhood lead poisoning in the United States through the control or elimination of lead sources in the environment, it continues to be an issue in many communities, primarily in low-income communities with a large percentage of deteriorating housing built before the elimination of lead in residential paint. The purpose of this study is to determine whether state laws aimed at preventing childhood lead poisoning are also effective in preventing recurring lead poisoning among children previously poisoned. An evaluation was conducted to determine whether laws in two representative states, Massachusetts and Ohio, have been effective in preventing recurrent lead poisoning among children less than 72 months of age previously poisoned, compared to a representative state (Mississippi) which at the time of the study had yet to develop legislation to prevent childhood lead poisoning. Compared to no legislation, unadjusted estimates showed children less than 72 months old, living in Massachusetts, previously identified as being lead poisoned, were 73% less likely to develop recurrent lead poisoning. However, this statistically significant association did not remain after controlling for other confounding variables. We did not find such a significant association when analyzing data from Ohio. While findings from unadjusted estimates indicated that state lead laws such as those in Massachusetts may be effective at preventing recurrent lead poisoning among young children, small numbers may have attenuated the power to obtain statistical significance during multivariate analysis. Our findings did not provide evidence that state lead laws, such as those in Ohio, were effective in preventing recurrent lead poisoning among young children. Further studies may be needed to confirm these findings. Published by Elsevier GmbH. JF - International journal of hygiene and environmental health AU - Kennedy, Chinaro AU - Lordo, Robert AU - Sucosky, Marissa Scalia AU - Boehm, Rona AU - Brown, Mary Jean AD - Centers for Disease Control and Prevention, National Center for Environmental Health/Agency for Toxic Substances and Disease Registry, Atlanta, GA, USA. Electronic address: gjn5@cdc.gov. ; Battelle Memorial Institute, Columbus, OH, USA. ; Centers for Disease Control and Prevention, National Center for Environmental Health/Agency for Toxic Substances and Disease Registry, Atlanta, GA, USA. Y1 - 2016/01// PY - 2016 DA - January 2016 SP - 110 EP - 117 VL - 219 IS - 1 KW - Hazardous Substances KW - 0 KW - Lead KW - 2P299V784P KW - Index Medicus KW - Lead law KW - Blood lead levels KW - Childhood lead poisoning KW - Housing KW - Humans KW - Child KW - Recurrence KW - Child, Preschool KW - Infant KW - State Government KW - Risk Reduction Behavior KW - Massachusetts KW - Incidence KW - Female KW - Male KW - Ohio KW - Lead -- adverse effects KW - Lead Poisoning -- prevention & control KW - Government Regulation KW - Paint KW - Environmental Exposure -- legislation & jurisprudence KW - Environmental Exposure -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1735330787?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+journal+of+hygiene+and+environmental+health&rft.atitle=Evaluating+the+effectiveness+of+state+specific+lead-based+paint+hazard+risk+reduction+laws+in+preventing+recurring+incidences+of+lead+poisoning+in+children.&rft.au=Kennedy%2C+Chinaro%3BLordo%2C+Robert%3BSucosky%2C+Marissa+Scalia%3BBoehm%2C+Rona%3BBrown%2C+Mary+Jean&rft.aulast=Kennedy&rft.aufirst=Chinaro&rft.date=2016-01-01&rft.volume=219&rft.issue=1&rft.spage=110&rft.isbn=&rft.btitle=&rft.title=International+journal+of+hygiene+and+environmental+health&rft.issn=1618-131X&rft_id=info:doi/10.1016%2Fj.ijheh.2015.09.009 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2016-09-01 N1 - Date created - 2015-11-20 N1 - Date revised - 2017-01-14 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1016/j.ijheh.2015.09.009 ER - TY - JOUR T1 - Reduction in Human Papillomavirus Vaccine Type Prevalence Among Young Women Screened for Cervical Cancer in an Integrated US Healthcare Delivery System in 2007 and 2012-2013 AN - 1780527252; PQ0002879753 AB - Background. In the United States, human papillomavirus (HPV) vaccine is recommended for 11- or 12-year-olds, and for young adults not previously vaccinated. Early vaccine impact can be measured by reductions in vaccine-type (VT) HPV prevalence. Methods. Consecutive residual cervical specimens were retained from women aged 20-29 years at Kaiser Permanente Northwest in 2007, 2012, and 2013. HPV genotypes were determined using L1 consensus polymerase chain reaction with type-specific hybridization to detect 37 types, including VT HPV (HPV type 6, 11, 16, and 18). We compared HPV prevalence in 2007 and 2012-2013, and we evaluated predictors of VT HPV and any-HPV prevalence in 2012-2013. Results. In 2012-2013, 31.9% of 4181 women had initiated HPV vaccination. VT HPV prevalence decreased from 10.6% in 2007 to 6.2% in 2012-2013 (P < .001). In 2012-2013, VT HPV prevalence was significantly lower among those who initiated vaccination <19 years (adjusted prevalence ratio, 0.1; 95% confidence interval, .1-.3) than among those who were not vaccinated, and higher among those who had chlamydia, human immunodeficiency virus, or pregnancy testing in the past year than among those who did not (adjusted prevalence ratio, 1.4; 95% confidence interval, 1.1-1.8). Conclusions. Reduction in VT HPV was found in young women in an integrated healthcare delivery system within 6 years of vaccine introduction, indicating early HPV vaccine impact. JF - Journal of Infectious Diseases AU - Dunne, Eileen F AU - Naleway, Allison AU - Smith, Ning AU - Crane, Bradley AU - Weinmann, Sheila AU - Braxton, Jim AU - Steinau, Martin AU - Unger, Elizabeth R AU - Markowitz, Lauri E AD - Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention Y1 - 2015/12/15/ PY - 2015 DA - 2015 Dec 15 SP - 1970 EP - 1975 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 212 IS - 12 SN - 0022-1899, 0022-1899 KW - Immunology Abstracts; Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - impact KW - HPV KW - HPV type prevalence KW - vaccine KW - Cervical cancer KW - Genotypes KW - Vaccination KW - Cancer KW - Pregnancy KW - USA KW - Health care KW - Infectious diseases KW - Human immunodeficiency virus KW - Polymerase chain reaction KW - Females KW - Young adults KW - Vaccines KW - Cervix KW - Sexually transmitted diseases KW - Chlamydia KW - Human papillomavirus KW - V 22360:AIDS and HIV KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1780527252?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Reduction+in+Human+Papillomavirus+Vaccine+Type+Prevalence+Among+Young+Women+Screened+for+Cervical+Cancer+in+an+Integrated+US+Healthcare+Delivery+System+in+2007+and+2012-2013&rft.au=Dunne%2C+Eileen+F%3BNaleway%2C+Allison%3BSmith%2C+Ning%3BCrane%2C+Bradley%3BWeinmann%2C+Sheila%3BBraxton%2C+Jim%3BSteinau%2C+Martin%3BUnger%2C+Elizabeth+R%3BMarkowitz%2C+Lauri+E&rft.aulast=Dunne&rft.aufirst=Eileen&rft.date=2015-12-15&rft.volume=212&rft.issue=12&rft.spage=1970&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiv342 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-04-01 N1 - Last updated - 2016-08-03 N1 - SubjectsTermNotLitGenreText - Cervical cancer; Polymerase chain reaction; Genotypes; Vaccines; Cervix; Vaccination; Pregnancy; Infectious diseases; Health care; Human immunodeficiency virus; Young adults; Females; Cancer; Sexually transmitted diseases; Human papillomavirus; Chlamydia; USA DO - http://dx.doi.org/10.1093/infdis/jiv342 ER - TY - JOUR T1 - A Newly Emerged Swine-Origin Influenza A(H3N2) Variant Dampens Host Antiviral Immunity but Induces Potent Inflammasome Activation AN - 1780498420; PQ0002879747 AB - We compared the innate immune response to a newly emerged swine-origin influenza A(H3N2) variant containing the M gene from 2009 pandemic influenza A(H1N1), termed "A(H3N2)vpM," to the immune responses to the 2010 swine-origin influenza A(H3N2) variant and seasonal influenza A(H3N2). Our results demonstrated that A(H3N2)vpM-induced myeloid dendritic cells secreted significantly lower levels of type I interferon (IFN) but produced significantly higher levels of proinflammatory cytokines and induced potent inflammasome activation. The reduction in antiviral immunity with increased inflammatory responses upon A(H3N2)vpM infection suggest that these viruses have the potential for increased disease severity in susceptible hosts. JF - Journal of Infectious Diseases AU - Cao, Weiping AU - Mishina, Margarita AU - Ranjan, Priya AU - De La Cruz, Juan A AU - Kim, Jin Hyang AU - Garten, Rebecca AU - Kumar, Amrita AU - Garcia-Sastre, Adolfo AU - Katz, Jacqueline M AU - Gangappa, Shivaprakash AU - Sambhara, Suryaprakash AD - Immunology and Pathogenesis Branch, wcao@cdc.gov Y1 - 2015/12/15/ PY - 2015 DA - 2015 Dec 15 SP - 1923 EP - 1929 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 212 IS - 12 SN - 0022-1899, 0022-1899 KW - Immunology Abstracts; Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - A(H3N2)vpM KW - myeloid dendritic cell KW - proinflammatory cytokines KW - type I IFN KW - ROS KW - inflammasome activation KW - Viruses KW - M gene KW - Immunity KW - Infection KW - Inflammation KW - Cell activation KW - Influenza KW - Interferon KW - Dendritic cells KW - pandemics KW - Sulfur dioxide KW - Infectious diseases KW - Immune response KW - Seasonal variations KW - V 22350:Immunology KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1780498420?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=A+Newly+Emerged+Swine-Origin+Influenza+A%28H3N2%29+Variant+Dampens+Host+Antiviral+Immunity+but+Induces+Potent+Inflammasome+Activation&rft.au=Cao%2C+Weiping%3BMishina%2C+Margarita%3BRanjan%2C+Priya%3BDe+La+Cruz%2C+Juan+A%3BKim%2C+Jin+Hyang%3BGarten%2C+Rebecca%3BKumar%2C+Amrita%3BGarcia-Sastre%2C+Adolfo%3BKatz%2C+Jacqueline+M%3BGangappa%2C+Shivaprakash%3BSambhara%2C+Suryaprakash&rft.aulast=Cao&rft.aufirst=Weiping&rft.date=2015-12-15&rft.volume=212&rft.issue=12&rft.spage=1923&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiv330 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-04-01 N1 - Last updated - 2016-08-03 N1 - SubjectsTermNotLitGenreText - Influenza; Dendritic cells; Interferon; pandemics; M gene; Immunity; Infection; Cell activation; Inflammation; Sulfur dioxide; Infectious diseases; Viruses; Immune response; Seasonal variations DO - http://dx.doi.org/10.1093/infdis/jiv330 ER - TY - JOUR T1 - In Vitro Efficacy of Antiviral Compounds against Enterovirus D68 AN - 1832245312; PQ0002380841 AB - In 2014, the United States experienced a large outbreak of severe respiratory illness associated with enterovirus D68 (EV-D68). We used a homogeneous, cell-based assay to assess the antiviral activity of compounds developed for EV/rhinovirus infection or other indications. Three of 15 compounds were highly active against all four strains tested (the prototype and three 2014 strains), with 50% effective concentrations of 0.0012 to 0.027 mu M. Additional studies are needed to assess their in vivo efficacy against EV-D68. JF - Antimicrobial Agents & Chemotherapy AU - Rhoden, Eric AU - Zhang, Mingyu AU - Nix, W Allan AU - Oberste, M Steven AD - << + $0, soberste@cdc.gov. Y1 - 2015/12// PY - 2015 DA - December 2015 SP - 7779 EP - 7781 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 59 IS - 12 SN - 0066-4804, 0066-4804 KW - Virology & AIDS Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Enterovirus KW - Picornaviridae KW - Antiviral activity KW - Infection KW - A 01340:Antibiotics & Antimicrobials KW - V 22410:Animal Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1832245312?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=In+Vitro+Efficacy+of+Antiviral+Compounds+against+Enterovirus+D68&rft.au=Rhoden%2C+Eric%3BZhang%2C+Mingyu%3BNix%2C+W+Allan%3BOberste%2C+M+Steven&rft.aulast=Rhoden&rft.aufirst=Eric&rft.date=2015-12-01&rft.volume=59&rft.issue=12&rft.spage=7779&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.00766-15 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-10-01 N1 - Number of references - 30 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Infection; Antiviral activity; Enterovirus; Picornaviridae DO - http://dx.doi.org/10.1128/AAC.00766-15 ER - TY - JOUR T1 - Predictive Value of School-Aged Children's Schistosomiasis Prevalence and Egg Intensity for Other Age Groups in Western Kenya AN - 1787965170; PQ0002931885 AB - World Health Organization recommendations for the timing and target population for mass drug administration (MDA) for schistosomiasis are based on the prevalence of infection in school children within a given community. In a large study comparing MDA approaches for Schistosoma mansoni control, we evaluated whether prevalence of infection and egg burdens in 9- to 12-year-old students reflected infection levels in young children and adults in the same community. Cross-sectional surveys of preadolescents (9-12 years old) were compared with those of first year students (5-8 years old) in 225 villages and adults (20-55 years old) in 150 villages along the Kenyan shores of Lake Victoria. Village schistosomiasis prevalence and intensity levels in preadolescents strongly correlated (P< 0.0001) with prevalence and infection intensity for other age groups in the community. Our findings suggest that S. mansoni prevalence and intensity among 9- to 12-year-olds are valid for community sampling purposes in mapping for MDAs. JF - American Journal of Tropical Medicine and Hygiene AU - Mwinzi, Pauline N M AU - Muchiri, Geoffrey AU - Wiegand, Ryan E AU - Omedo, Martin AU - Abudho, Bernard AU - Karanja, Diana M S AU - Montgomery, Susan P AU - Secor, W Evan AD - Center for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya, was4@cdc.gov Y1 - 2015/12// PY - 2015 DA - December 2015 SP - 1311 EP - 1317 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 93 IS - 6 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts KW - Schistosoma mansoni KW - Prediction KW - Parasites KW - Age KW - Organizations KW - Shores KW - Infection KW - Eggs KW - Public health KW - Lakes KW - Sampling KW - Mapping KW - Drugs KW - Schistosomiasis KW - Children KW - Education establishments KW - Africa, Victoria L. KW - Villages KW - Age groups KW - Hygiene KW - K 03400:Human Diseases KW - Q1 08604:Stock assessment and management KW - H 0500:General KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1787965170?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Predictive+Value+of+School-Aged+Children%27s+Schistosomiasis+Prevalence+and+Egg+Intensity+for+Other+Age+Groups+in+Western+Kenya&rft.au=Mwinzi%2C+Pauline+N+M%3BMuchiri%2C+Geoffrey%3BWiegand%2C+Ryan+E%3BOmedo%2C+Martin%3BAbudho%2C+Bernard%3BKaranja%2C+Diana+M+S%3BMontgomery%2C+Susan+P%3BSecor%2C+W+Evan&rft.aulast=Mwinzi&rft.aufirst=Pauline+N&rft.date=2015-12-01&rft.volume=93&rft.issue=6&rft.spage=1311&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.15-0467 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-05-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Prediction; Parasites; Organizations; Schistosomiasis; Age groups; Hygiene; Education establishments; Eggs; Public health; Lakes; Age; Shores; Mapping; Sampling; Children; Infection; Drugs; Villages; Schistosoma mansoni; Africa, Victoria L. DO - http://dx.doi.org/10.4269/ajtmh.15-0467 ER - TY - JOUR T1 - A Review of Melioidosis Cases in the Americas AN - 1787961738; PQ0002931858 AB - Melioidosis is a bacterial infection caused by Burkholderia pseudomallei, a gram-negative saprophytic bacillus. Cases occur sporadically in the Americas with an increasing number of cases observed among people with no travel history to endemic countries. To better understand the incidence of the disease in the Americas, we reviewed the literature, including unpublished cases reported to the Centers for Disease Control and Prevention. Of 120 identified human cases, occurring between 1947 and June 2015, 95 cases (79%) were likely acquired in the Americas; the mortality rate was 39%. Burkholderia pseudomallei appears to be widespread in South, Central, and North America. JF - American Journal of Tropical Medicine and Hygiene AU - Benoit, Tina J AU - Blaney, David D AU - Doker, Thomas J AU - Gee, Jay E AU - Elrod, Mindy G AU - Rolim, Dionne B AU - Inglis, Timothy J J AU - Hoffmaster, Alex R AU - Bower, William A AU - Walke, Henry T AD - Bacterial Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, Georgia, dblaney@cdc.gov Y1 - 2015/12// PY - 2015 DA - December 2015 SP - 1134 EP - 1139 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 93 IS - 6 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts C: Algology, Mycology & Protozoology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts KW - Burkholderia pseudomallei KW - Travel KW - North America KW - Historical account KW - Mortality KW - Melioidosis KW - Disease control KW - Infection KW - Prevention KW - Endemic species KW - Literature reviews KW - Reviews KW - Hygiene KW - Bacillus KW - Mortality causes KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - K 03400:Human Diseases KW - J 02400:Human Diseases KW - Q1 08485:Species interactions: pests and control KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1787961738?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=A+Review+of+Melioidosis+Cases+in+the+Americas&rft.au=Benoit%2C+Tina+J%3BBlaney%2C+David+D%3BDoker%2C+Thomas+J%3BGee%2C+Jay+E%3BElrod%2C+Mindy+G%3BRolim%2C+Dionne+B%3BInglis%2C+Timothy+J+J%3BHoffmaster%2C+Alex+R%3BBower%2C+William+A%3BWalke%2C+Henry+T&rft.aulast=Benoit&rft.aufirst=Tina&rft.date=2015-12-01&rft.volume=93&rft.issue=6&rft.spage=1134&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.15-0405 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-05-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Endemic species; Literature reviews; Disease control; Hygiene; Mortality causes; Travel; Mortality; Reviews; Melioidosis; Infection; Historical account; Prevention; Burkholderia pseudomallei; Bacillus; North America DO - http://dx.doi.org/10.4269/ajtmh.15-0405 ER - TY - JOUR T1 - Effect of nitrite on the formation of halonitromethanes during chlorination of organic matter from different origin AN - 1784735502; 2016-035818 AB - Occurrence of halonitromethanes (HNMs) in drinking water has been a public concern due to the potential risks to human health. Though quite a lot of work has been carried out to understand the formation of HNMs, the relationship between HNMs formation and the nitrite remains unclear. In this study, the effects of nitrite on the formation of HNMs during chlorination of organic matter from different origin were assessed. Organic matter (OM) derived from phoenix tree (fallen leaves: FLOM; green leaves: GLOM) and Microcystis aeruginosa (intracellular organic matter: IOM) were used to mimic the allochthonous and autochthonous organic matter in surface water, respectively. Results showed that HNMs yields were significantly enhanced with the addition of nitrite, and the highest enhancement was observed for FLOM, successively followed by GLOM and IOM, suggesting that the contribution of nitrite to HNMs formation was positively related with SUVA (an indicator for aromaticity) of OM. Therefore, the nitrite contamination should be strictly controlled for the source water dominated by allochthonous OM, which may significantly reduce the formation of HNMs during chlorination. Moreover, given a certain nitrite level, the higher pH resulted in higher stimulation of HNM formation, yet the chlorine dose (always added in excess resulting in residual reactive chlorine), reaction time and temperature did not show obvious influence. Abstract Copyright (2015) Elsevier, B.V. JF - Journal of Hydrology AU - Hong, Huachang AU - Qian, Lingya AU - Xiao, Zhuoqun AU - Zhang, Jianqing AU - Chen, Jianrong AU - Lin, Hongjun AU - Yu, Haiying AU - Shen, Liguo AU - Liang, Yan Y1 - 2015/12// PY - 2015 DA - December 2015 SP - 802 EP - 809 PB - Elsevier, Amsterdam VL - 531 IS - Part 3 SN - 0022-1694, 0022-1694 KW - chlorinated hydrocarbons KW - water quality KW - aliphatic hydrocarbons KW - vegetation KW - drinking water KW - environmental effects KW - statistical distribution KW - colorimetry KW - ultraviolet spectra KW - halogenated hydrocarbons KW - spectra KW - chemical composition KW - water pollution KW - nitrite ion KW - chemical analysis KW - methane KW - pollutants KW - biochemistry KW - physicochemical properties KW - pollution KW - alkanes KW - organic compounds KW - halonitromethane KW - hydrocarbons KW - 22:Environmental geology KW - 02A:General geochemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1784735502?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Hydrology&rft.atitle=Effect+of+nitrite+on+the+formation+of+halonitromethanes+during+chlorination+of+organic+matter+from+different+origin&rft.au=Hong%2C+Huachang%3BQian%2C+Lingya%3BXiao%2C+Zhuoqun%3BZhang%2C+Jianqing%3BChen%2C+Jianrong%3BLin%2C+Hongjun%3BYu%2C+Haiying%3BShen%2C+Liguo%3BLiang%2C+Yan&rft.aulast=Hong&rft.aufirst=Huachang&rft.date=2015-12-01&rft.volume=531&rft.issue=Part+3&rft.spage=802&rft.isbn=&rft.btitle=&rft.title=Journal+of+Hydrology&rft.issn=00221694&rft_id=info:doi/10.1016%2Fj.jhydrol.2015.10.046 L2 - http://www.sciencedirect.com/science/journal/00221694 LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2016, American Geosciences Institute. Reference includes data from CAPCAS, Elsevier Scientific Publishers, Amsterdam, Netherlands N1 - Date revised - 2016-01-01 N1 - Number of references - 30 N1 - Document feature - illus. incl. 2 tables N1 - SuppNotes - Includes appendices N1 - Last updated - 2016-04-28 N1 - CODEN - JHYDA7 N1 - SubjectsTermNotLitGenreText - aliphatic hydrocarbons; alkanes; biochemistry; chemical analysis; chemical composition; chlorinated hydrocarbons; colorimetry; drinking water; environmental effects; halogenated hydrocarbons; halonitromethane; hydrocarbons; methane; nitrite ion; organic compounds; physicochemical properties; pollutants; pollution; spectra; statistical distribution; ultraviolet spectra; vegetation; water pollution; water quality DO - http://dx.doi.org/10.1016/j.jhydrol.2015.10.046 ER - TY - JOUR T1 - Preventing community-wide transmission of Cryptosporidium: a proactive public health response to a swimming pool-associated outbreak - Auglaize County, Ohio, USA AN - 1762382822; PQ0002459167 AB - The incidence of recreational water-associated outbreaks in the United States has significantly increased, driven, at least in part, by outbreaks both caused by Cryptosporidium and associated with treated recreational water venues. Because of the parasite's extreme chlorine tolerance, transmission can occur even in well-maintained treated recreational water venues (e.g. pools) and a focal cryptosporidiosis outbreak can evolve into a community-wide outbreak associated with multiple recreational water venues and settings (e.g. childcare facilities). In August 2004 in Auglaize County, Ohio, multiple cryptosporidiosis cases were identified and anecdotally linked to pool A. Within 5 days of the first case being reported, pool A was hyperchlorinated to achieve 99.9% Cryptosporidium inactivition. A case-control study was launched to epidemiologically ascertain the outbreak source 11 days later. A total of 150 confirmed and probable cases were identified; the temporal distribution of illness onset was peaked, indicating a point-source exposure. Cryptosporidiosis was significantly associated with swimming in pool A (matched odds ratio 121.7, 95% confidence interval 27.4- infinity ) but not with another venue or setting. The findings of this investigation suggest that proactive implementation of control measures, when increased Cryptosporidium transmission is detected but before an outbreak source is epidemiologically ascertained, might prevent a focal cryptosporidiosis outbreak from evolving into a community-wide outbreak. JF - Epidemiology and Infection AU - Cope, J R AU - Prosser, A AU - Nowicki, S AU - Roberts, M W AU - Roberts, J M AU - Scheer, D AU - Anderson, C AU - Longsworth, A AU - Parsons, C AU - Goldschmidt, D AU - Johnston, S AU - Bishop, H AU - Xiao, L AU - Hill, V AU - Beach, M AU - Hlavsa, M C AD - Centres for Disease Control and Prevention, Atlanta, GA, USA, jcope@cdc.gov Y1 - 2015/12// PY - 2015 DA - December 2015 SP - 3459 EP - 3467 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 143 IS - 16 SN - 0950-2688, 0950-2688 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Health & Safety Science Abstracts KW - Daycare KW - Swimming KW - Temporal distribution KW - Chlorine KW - Disease transmission KW - Public health KW - Cryptosporidiosis KW - Recreation areas KW - Cryptosporidium KW - Outbreaks KW - USA, Ohio KW - K 03400:Human Diseases KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1762382822?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Preventing+community-wide+transmission+of+Cryptosporidium%3A+a+proactive+public+health+response+to+a+swimming+pool-associated+outbreak+-+Auglaize+County%2C+Ohio%2C+USA&rft.au=Cope%2C+J+R%3BProsser%2C+A%3BNowicki%2C+S%3BRoberts%2C+M+W%3BRoberts%2C+J+M%3BScheer%2C+D%3BAnderson%2C+C%3BLongsworth%2C+A%3BParsons%2C+C%3BGoldschmidt%2C+D%3BJohnston%2C+S%3BBishop%2C+H%3BXiao%2C+L%3BHill%2C+V%3BBeach%2C+M%3BHlavsa%2C+M+C&rft.aulast=Cope&rft.aufirst=J&rft.date=2015-12-01&rft.volume=143&rft.issue=16&rft.spage=3459&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268815000813 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Number of references - 32 N1 - Last updated - 2016-03-30 N1 - SubjectsTermNotLitGenreText - Swimming; Cryptosporidiosis; Chlorine; Public health; Disease transmission; Daycare; Temporal distribution; Recreation areas; Outbreaks; Cryptosporidium; USA, Ohio DO - http://dx.doi.org/10.1017/S0950268815000813 ER - TY - JOUR T1 - A Mixed-Methods Assessment of a Brief Smoking Cessation Intervention Implemented in Ohio Public Health Clinics, 2013 AN - 1762362395; PQ0002364492 AB - In 2006, the state of Ohio initiated the implementation of a brief smoking cessation intervention (5As: Ask, Advise, Assess, Assist, and Arrange) in select public health clinics that serve low-income pregnant and post-partum women. Funds later became available to expand the program statewide by 2015. However, close to half of the clinics initially trained stopped implementation of the 5As. To help guide the proposed statewide expansion plan for implementation of the 5As, this study assessed barriers and facilitators related to 5As implementation among clinics that had ever received training. Methods: A mixed-methods approach was used, comprising semi-structured interviews with clinic program directors (n = 21) and a survey of clinic staff members (n = 120), to assess implementation-related barriers, facilitators, training needs, and staff confidence in delivering the 5As. Results: Semi-structured interviews of program directors elucidated implementation barriers including time constraints, low self-efficacy in engaging resistant clients, and paperwork-related documentation challenges. Facilitators included availability of community referral resources, and integration of cessation interventions into the clinic workflow. Program directors believed they would benefit from more hands-on training in delivering the 5As. The survey results showed that a majority of staff felt confident advising (61 %) or referring clients for tobacco dependence treatment (74 %), but fewer felt confident about discussing treatment options with clients (29 %) or providing support to clients who had relapsed (30 %). Conclusions: Time constraints and documentation issues were major barriers to implementing the 5As. Simplified documentation processes and training enhancements, coupled with systems change, may enhance delivery of evidence-based smoking cessation interventions. JF - Maternal and Child Health Journal AU - Agaku, Israel T AU - Olaiya, Oluwatosin AU - Quinn, Celia AU - Tong, Van T AU - Kuiper, Nicole M AU - Conrey, Elizabeth J AU - Sharma, Andrea J AU - Mullen, Sierra AU - Dee, Deborah AD - Office on Smoking and Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA, iagaku@cdc.gov Y1 - 2015/12// PY - 2015 DA - December 2015 SP - 2654 EP - 2662 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 19 IS - 12 SN - 1092-7875, 1092-7875 KW - Health & Safety Science Abstracts KW - Smoking KW - Funds KW - Training KW - Tobacco KW - Intervention KW - Socioeconomics KW - USA, Ohio KW - Public health KW - Pregnancy KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1762362395?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Maternal+and+Child+Health+Journal&rft.atitle=A+Mixed-Methods+Assessment+of+a+Brief+Smoking+Cessation+Intervention+Implemented+in+Ohio+Public+Health+Clinics%2C+2013&rft.au=Agaku%2C+Israel+T%3BOlaiya%2C+Oluwatosin%3BQuinn%2C+Celia%3BTong%2C+Van+T%3BKuiper%2C+Nicole+M%3BConrey%2C+Elizabeth+J%3BSharma%2C+Andrea+J%3BMullen%2C+Sierra%3BDee%2C+Deborah&rft.aulast=Agaku&rft.aufirst=Israel&rft.date=2015-12-01&rft.volume=19&rft.issue=12&rft.spage=2654&rft.isbn=&rft.btitle=&rft.title=Maternal+and+Child+Health+Journal&rft.issn=10927875&rft_id=info:doi/10.1007%2Fs10995-015-1786-y LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Number of references - 24 N1 - Last updated - 2016-02-04 N1 - SubjectsTermNotLitGenreText - Smoking; Funds; Training; Tobacco; Socioeconomics; Intervention; Pregnancy; Public health; USA, Ohio DO - http://dx.doi.org/10.1007/s10995-015-1786-y ER - TY - JOUR T1 - In Vitro and Molecular Surveillance for Antimalarial Drug Resistance in Plasmodium falciparum Parasites in Western Kenya Reveals Sustained Artemisinin Sensitivity and Increased Chloroquine Sensitivity AN - 1758245004; PQ0002380925 AB - Malaria control is hindered by the evolution and spread of resistance to antimalarials, necessitating multiple changes to drug policies over time. A comprehensive antimalarial drug resistance surveillance program is vital for detecting the potential emergence of resistance to antimalarials, including current artemisinin-based combination therapies. An antimalarial drug resistance surveillance study involving 203 Plasmodium falciparum malaria-positive children was conducted in western Kenya between 2010 and 2013. Specimens from enrolled children were analyzed in vitro for sensitivity to chloroquine (CQ), amodiaquine (AQ), mefloquine (MQ), lumefantrine, and artemisinin derivatives (artesunate and dihydroartemisinin) and for drug resistance allele polymorphisms in P. falciparum crt (Pfcrt), Pfmdr-1, and the K13 propeller domain (K13). We observed a significant increase in the proportion of samples with the Pfcrt wild-type (CVMNK) genotype, from 61.2% in 2010 to 93.0% in 2013 (P < 0.0001), and higher proportions of parasites with elevated sensitivity to CQ in vitro. The majority of isolates harbored the wild-type N allele in Pfmdr-1 codon 86 (93.5%), with only 7 (3.50%) samples with the N86Y mutant allele (the mutant nucleotide is underlined). Likewise, most isolates harbored the wild-type Pfmdr-1 D1246 allele (79.8%), with only 12 (6.38%) specimens with the D1246Y mutant allele and 26 (13.8%) with mixed alleles. All the samples had a single copy of the Pfmdr-1 gene (mean of 0.907 plus or minus 0.141 copies). None of the sequenced parasites had mutations in K13. Our results suggest that artemisinin is likely to remain highly efficacious and that CQ sensitivity appears to be on the rise in western Kenya. JF - Antimicrobial Agents & Chemotherapy AU - Lucchi, Naomi W AU - Komino, Franklin AU - Okoth, Sheila Akinyi AU - Goldman, Ira AU - Onyona, Philip AU - Wiegand, Ryan E AU - Juma, Elizabeth AU - Shi, Ya Ping AU - Barnwell, John W AU - Udhayakumar, Venkatachalam AD - << + $0, NLucchi@cdc.gov. Y1 - 2015/12// PY - 2015 DA - December 2015 SP - 7540 EP - 7547 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 59 IS - 12 SN - 0066-4804, 0066-4804 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Parasites KW - Human diseases KW - Allelles KW - Drug resistance KW - Nucleotide sequence KW - Malaria KW - Public health KW - Kenya KW - Mefloquine KW - artesunate KW - Amodiaquine KW - Mutations KW - Chloroquine KW - Plasmodium falciparum KW - Children KW - Nucleotides KW - Codons KW - Dihydroartemisinin KW - artemisinin KW - Mutation KW - Evolution KW - A 01340:Antibiotics & Antimicrobials KW - K 03400:Human Diseases KW - Q1 08604:Stock assessment and management KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1758245004?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=In+Vitro+and+Molecular+Surveillance+for+Antimalarial+Drug+Resistance+in+Plasmodium+falciparum+Parasites+in+Western+Kenya+Reveals+Sustained+Artemisinin+Sensitivity+and+Increased+Chloroquine+Sensitivity&rft.au=Lucchi%2C+Naomi+W%3BKomino%2C+Franklin%3BOkoth%2C+Sheila+Akinyi%3BGoldman%2C+Ira%3BOnyona%2C+Philip%3BWiegand%2C+Ryan+E%3BJuma%2C+Elizabeth%3BShi%2C+Ya+Ping%3BBarnwell%2C+John+W%3BUdhayakumar%2C+Venkatachalam&rft.aulast=Lucchi&rft.aufirst=Naomi&rft.date=2015-12-01&rft.volume=59&rft.issue=12&rft.spage=7540&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.01894-15 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-01-01 N1 - Number of references - 51 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Parasites; Human diseases; Mutations; Allelles; Nucleotide sequence; Drug resistance; Malaria; Nucleotides; Public health; Amodiaquine; Chloroquine; Children; Codons; artemisinin; Dihydroartemisinin; Mefloquine; artesunate; Mutation; Evolution; Plasmodium falciparum; Kenya DO - http://dx.doi.org/10.1128/AAC.01894-15 ER - TY - JOUR T1 - Trends in Exposure to Chemicals in Personal Care and Consumer Products. AN - 1728258448; 26342608 AB - Synthetic organic chemicals can be used in personal care and consumer products. Data on potential human health effects of these chemicals are limited-sometimes even contradictory-but because several of these chemicals are toxic in experimental animals, alternative compounds are entering consumer markets. Nevertheless, limited information exists on consequent exposure trends to both the original chemicals and their replacements. Biomonitoring (measuring concentrations of chemicals or their metabolites in people) provides invaluable information for exposure assessment. We use phthalates and bisphenol A-known industrial chemicals-and organophosphate insecticides as case studies to show exposure trends to these chemicals and their replacements (e.g., other phthalates, non-phthalate plasticizers, various bisphenols, pyrethroid insecticides) among the US general population. We compare US trends to national trends from Canada and Germany. Exposure to the original compounds is still prevalent among these general populations, but exposures to alternative chemicals may be increasing. JF - Current environmental health reports AU - Calafat, Antonia M AU - Valentin-Blasini, Liza AU - Ye, Xiaoyun AD - Centers for Disease Control and Prevention, 4770 Buford Hwy, MS F17, Atlanta, GA, 30341, USA. aic7@cdc.gov. ; Centers for Disease Control and Prevention, 4770 Buford Hwy, MS F19, Atlanta, GA, 30341, USA. lbv5@cdc.gov. ; Centers for Disease Control and Prevention, 4770 Buford Hwy, MS F53, Atlanta, GA, 30341, USA. xay5@cdc.gov. Y1 - 2015/12// PY - 2015 DA - December 2015 SP - 348 EP - 355 VL - 2 IS - 4 KW - Benzhydryl Compounds KW - 0 KW - Cosmetics KW - Endocrine Disruptors KW - Insecticides KW - Organophosphates KW - Parabens KW - Phenols KW - Phthalic Acids KW - Plasticizers KW - bisphenol A KW - MLT3645I99 KW - Index Medicus KW - Phthalates KW - Exposure KW - Endocrine disruptors KW - Pesticides KW - Biomonitoring KW - DINCH KW - Bisphenol KW - United States KW - Animals KW - Consumer Product Safety -- standards KW - Canada KW - Humans KW - Surveys and Questionnaires KW - Parabens -- analysis KW - Endocrine Disruptors -- analysis KW - Germany KW - Insecticides -- analysis KW - Plasticizers -- analysis KW - Environmental Monitoring -- methods KW - Household Products -- analysis KW - Environmental Exposure -- analysis KW - Household Products -- adverse effects KW - Organophosphates -- analysis KW - Cosmetics -- adverse effects KW - Phthalic Acids -- analysis KW - Phenols -- analysis KW - Cosmetics -- chemistry KW - Benzhydryl Compounds -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1728258448?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Current+environmental+health+reports&rft.atitle=Trends+in+Exposure+to+Chemicals+in+Personal+Care+and+Consumer+Products.&rft.au=Calafat%2C+Antonia+M%3BValentin-Blasini%2C+Liza%3BYe%2C+Xiaoyun&rft.aulast=Calafat&rft.aufirst=Antonia&rft.date=2015-12-01&rft.volume=2&rft.issue=4&rft.spage=348&rft.isbn=&rft.btitle=&rft.title=Current+environmental+health+reports&rft.issn=2196-5412&rft_id=info:doi/10.1007%2Fs40572-015-0065-9 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2016-05-11 N1 - Date created - 2015-10-28 N1 - Date revised - 2017-01-14 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1007/s40572-015-0065-9 ER - TY - JOUR T1 - Assessment of blood-brain barrier penetration of miltefosine used to treat a fatal case of granulomatous amebic encephalitis possibly caused by an unusual Balamuthia mandrillaris strain. AN - 1722185893; 26329128 AB - Balamuthia mandrillaris, a free-living ameba, causes rare but frequently fatal granulomatous amebic encephalitis (GAE). Few patients have survived after receiving experimental drug combinations, with or without brain lesion excisions. Some GAE survivors have been treated with a multi-drug regimen including miltefosine, an investigational anti-leishmanial agent with in vitro amebacidal activity. Miltefosine dosing for GAE has been based on leishmaniasis dosing because no data exist in humans concerning its pharmacologic distribution in the central nervous system. We describe results of limited cerebrospinal fluid (CSF) and serum drug level testing performed during clinical management of a child with fatal GAE who was treated with a multiple drug regimen including miltefosine. Brain biopsy specimens, CSF, and sera were tested for B. mandrillaris using multiple techniques, including culture, real-time polymerase chain reaction, immunohistochemical techniques, and serology. CSF and serum miltefosine levels were determined using a liquid chromatography method coupled to tandem mass spectrometry. The CSF miltefosine concentration on hospital admission day 12 was 0.4 μg/mL. The serum miltefosine concentration on day 37, about 80 h post-miltefosine treatment, was 15.3 μg/mL. These are the first results confirming some blood-brain barrier penetration by miltefosine in a human, although with low-level CSF accumulation. Further evaluation of brain parenchyma penetration is required to determine optimal miltefosine dosing for Balamuthia GAE, balanced with the drug's toxicity profile. Additionally, the Balamuthia isolate was evaluated by real-time polymerase chain reaction (PCR), demonstrating genetic variability in 18S ribosomal RNA (18S rRNA) sequences and possibly signaling the first identification of multiple Balamuthia strains with varying pathogenicities. JF - Parasitology research AU - Roy, Sharon L AU - Atkins, Jane T AU - Gennuso, Rosemaria AU - Kofos, Danny AU - Sriram, Rama R AU - Dorlo, Thomas P C AU - Hayes, Teresa AU - Qvarnstrom, Yvonne AU - Kucerova, Zuzana AU - Guglielmo, B Joseph AU - Visvesvara, Govinda S AD - Division of Foodborne, Waterborne and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, 30329, USA. str2@cdc.gov. ; Methodist Children's Hospital, San Antonio, TX, 78229, USA. ; Division of Foodborne, Waterborne and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, 30329, USA. ; Department of Pharmacy and Pharmacology, Slotervaart Hospital-The Netherlands Cancer Institute, 1066 EC, Amsterdam, The Netherlands. ; Department of Pathology, Methodist Hospital, San Antonio, TX, 78229, USA. ; Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA, 30329, USA. ; Department of Clinical Pharmacy, School of Pharmacy, University of California, San Francisco, San Francisco, CA, 94143, USA. Y1 - 2015/12// PY - 2015 DA - December 2015 SP - 4431 EP - 4439 VL - 114 IS - 12 KW - Amebicides KW - 0 KW - Phosphorylcholine KW - 107-73-3 KW - miltefosine KW - 53EY29W7EC KW - Index Medicus KW - Miltefosine KW - Granulomatous KW - Balamuthia KW - Encephalitis KW - Fatal Outcome KW - Humans KW - Brain -- pathology KW - Child KW - Brain -- parasitology KW - Male KW - Blood-Brain Barrier -- drug effects KW - Amebiasis -- parasitology KW - Phosphorylcholine -- administration & dosage KW - Balamuthia mandrillaris -- drug effects KW - Amebiasis -- drug therapy KW - Amebicides -- pharmacokinetics KW - Encephalitis -- drug therapy KW - Blood-Brain Barrier -- parasitology KW - Phosphorylcholine -- pharmacokinetics KW - Balamuthia mandrillaris -- isolation & purification KW - Amebicides -- administration & dosage KW - Encephalitis -- parasitology KW - Phosphorylcholine -- analogs & derivatives UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1722185893?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Parasitology+research&rft.atitle=Assessment+of+blood-brain+barrier+penetration+of+miltefosine+used+to+treat+a+fatal+case+of+granulomatous+amebic+encephalitis+possibly+caused+by+an+unusual+Balamuthia+mandrillaris+strain.&rft.au=Roy%2C+Sharon+L%3BAtkins%2C+Jane+T%3BGennuso%2C+Rosemaria%3BKofos%2C+Danny%3BSriram%2C+Rama+R%3BDorlo%2C+Thomas+P+C%3BHayes%2C+Teresa%3BQvarnstrom%2C+Yvonne%3BKucerova%2C+Zuzana%3BGuglielmo%2C+B+Joseph%3BVisvesvara%2C+Govinda+S&rft.aulast=Roy&rft.aufirst=Sharon&rft.date=2015-12-01&rft.volume=114&rft.issue=12&rft.spage=4431&rft.isbn=&rft.btitle=&rft.title=Parasitology+research&rft.issn=1432-1955&rft_id=info:doi/10.1007%2Fs00436-015-4684-8 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2016-06-24 N1 - Date created - 2015-10-13 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Cited By: J Clin Microbiol. 2003 Jul;41(7):3175-80 [12843060] Clin Infect Dis. 2003 Nov 15;37(10):1304-12 [14583863] Arch Pathol Lab Med. 2004 Apr;128(4):466-8 [15043486] Microbiology. 2004 Sep;150(Pt 9):2837-42 [15347743] Vet Pathol. 2004 Sep;41(5):506-10 [15347823] Emerg Infect Dis. 2004 Aug;10(8):1510-2 [15503402] Cancer Treat Rev. 1990 Sep;17(2-3):233-42 [2272038] J Clin Microbiol. 1990 Dec;28(12):2750-6 [2280005] Cancer Chemother Pharmacol. 1992;31(1):18-22 [1458555] J Eukaryot Microbiol. 1993 Jul-Aug;40(4):504-14 [8330028] J Clin Microbiol. 1996 Feb;34(2):385-8 [8789020] Antimicrob Agents Chemother. 1996 Mar;40(3):825-6 [8851625] Med J Aust. 1997 Jul 21;167(2):82-4 [9251693] J Infect Dis. 1999 May;179(5):1305-8 [10191243] J Eukaryot Microbiol. 2006 Mar-Apr;53(2):121-6 [16579814] Clin Infect Dis. 2006 May 1;42(9):1260-5 [16586385] J Clin Microbiol. 2006 Oct;44(10):3589-95 [17021087] Parasitol Res. 2007 Jan;100(2):423-6 [17033842] J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Apr 1;865(1-2):55-62 [18325856] Antimicrob Agents Chemother. 2008 Aug;52(8):2855-60 [18519729] Parasitol Res. 2009 Feb;104(3):663-70 [19039606] Clin Infect Dis. 2009 Apr 1;48(7):879-87 [19236272] J Immunol. 2009 Jun 1;182(11):7146-54 [19454711] Parasitol Res. 2009 Dec;106(1):279-81 [19685076] Pediatrics. 2010 Mar;125(3):e699-703 [20123772] Clin Infect Dis. 2010 Jul 15;51(2):e7-11 [20550438] MMWR Morb Mortal Wkly Rep. 2010 Sep 17;59(36):1165-70 [20847719] Clin Microbiol Rev. 2010 Oct;23(4):858-83 [20930076] Curr Opin Infect Dis. 2011 Apr;24(2):112-7 [21192259] J Eukaryot Microbiol. 2011 May-Jun;58(3):269-71 [21435080] Clin Vaccine Immunol. 2011 Aug;18(8):1297-301 [21653740] Antimicrob Agents Chemother. 2012 Jul;56(7):3864-72 [22585212] J Antimicrob Chemother. 2012 Nov;67(11):2576-97 [22833634] MMWR Morb Mortal Wkly Rep. 2013 Aug 23;62(33):666 [23965830] J Eukaryot Microbiol. 2013 Nov-Dec;60(6):626-33 [23879685] J Clin Microbiol. 2003 Jan;41(1):453-5 [12517892] Am J Trop Med Hyg. 2003 Jan;68(1):65-9 [12556151] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1007/s00436-015-4684-8 ER - TY - JOUR T1 - What Is the Added Benefit of Oropharyngeal Swabs Compared to Nasal Swabs Alone for Respiratory Virus Detection in Hospitalized Children Aged <10 Years? AN - 1776653913; PQ0002734363 AB - We evaluated the added value of collecting both nasal and oropharyngeal swabs, compared with collection of nasal swabs alone, for detection of common respiratory viruses by reverse transcription-polymerase chain reaction in hospitalized children aged <10 years. Nasal swabs had equal or greater sensitivity than oropharyngeal swabs for detection of respiratory syncytial virus, adenovirus, human metapneumovirus, rhinovirus, and influenza virus but not parainfluenza virus. The addition of an oropharyngeal swab, compared with use of a nasal swab alone, increased the frequency of detection of each respiratory virus by no more than 10% in children aged <10 years. JF - Journal of Infectious Diseases AU - Dawood, Fatimah S AU - Jara, Jorge AU - Estripeaut, Dora AU - Vergara, Ofelina AU - Luciani, Kathia AU - Corro, Mary AU - de Leon, Tirza AU - Saldana, Ricardo AU - Baires, Juan Miguel Castillo AU - Flores, Rafael Rauda AD - Influenza Division, fdawood@cdc.gov Y1 - 2015/11/15/ PY - 2015 DA - 2015 Nov 15 SP - 1600 EP - 1603 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 212 IS - 10 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - influenza, human KW - respiratory syncytial virus infections KW - parainfluenza KW - human metapneumovirus KW - children, hospitalized KW - Sensitivity KW - Viruses KW - Adenovirus KW - Children KW - Parainfluenza virus KW - Parainfluenza KW - Respiratory syncytial virus KW - Influenza KW - Influenza virus KW - Infectious diseases KW - Human metapneumovirus KW - Rhinovirus KW - Hospitals KW - H 1000:Occupational Safety and Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1776653913?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=What+Is+the+Added+Benefit+of+Oropharyngeal+Swabs+Compared+to+Nasal+Swabs+Alone+for+Respiratory+Virus+Detection+in+Hospitalized+Children+Aged+%26lt%3B10+Years%3F&rft.au=Dawood%2C+Fatimah+S%3BJara%2C+Jorge%3BEstripeaut%2C+Dora%3BVergara%2C+Ofelina%3BLuciani%2C+Kathia%3BCorro%2C+Mary%3Bde+Leon%2C+Tirza%3BSaldana%2C+Ricardo%3BBaires%2C+Juan+Miguel+Castillo%3BFlores%2C+Rafael+Rauda&rft.aulast=Dawood&rft.aufirst=Fatimah&rft.date=2015-11-15&rft.volume=212&rft.issue=10&rft.spage=1600&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiv265 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-03-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Influenza; Children; Parainfluenza; Sensitivity; Infectious diseases; Viruses; Hospitals; Respiratory syncytial virus; Influenza virus; Human metapneumovirus; Adenovirus; Rhinovirus; Parainfluenza virus DO - http://dx.doi.org/10.1093/infdis/jiv265 ER - TY - JOUR T1 - Mortality Risk After AIDS-Defining Opportunistic Illness Among HIV-Infected Persons-San Francisco, 1981-2012 AN - 1776654352; PQ0002734349 AB - Objective. To examine whether improved human immunodeficiency virus (HIV) treatment was associated with better survival after diagnosis of AIDS-defining opportunistic illnesses (AIDS-OIs) and how survival differed by AIDS-OI. Design. We used HIV surveillance data to conduct a survival analysis. Methods. We estimated survival probabilities after first AIDS-OI diagnosis among adult patients with AIDS in San Francisco during 3 treatment eras: 1981-1986; 1987-1996; and 1997-2012. We used Cox proportional hazards models to determine adjusted mortality risk by AIDS-OI in the years 1997-2012. Results. Among 20 858 patients with AIDS, the most frequently diagnosed AIDS-OIs were Pneumocystis pneumonia (39.1%) and Kaposi sarcoma (20.1%). Overall 5-year survival probability increased from 7% in 1981-1986 to 65% in 1997-2012. In 1997-2012, after adjustment for known confounders and using Pneumocystis pneumonia as the referent category, mortality rates after first AIDS-OI were highest for brain lymphoma (hazard ratio [HR], 5.14; 95% confidence interval [CI], 2.98-8.87) and progressive multifocal leukoencephalopathy (HR, 4.22; 95% CI, 2.49-7.17). Conclusions. Survival after first AIDS-OI diagnosis has improved markedly since 1981. Some AIDS-OIs remain associated with substantially higher mortality risk than others, even after adjustment for known confounders. Better prevention and treatment strategies are still needed for AIDS-OIs occurring in the current HIV treatment era. JF - Journal of Infectious Diseases AU - Djawe, Kpandja AU - Buchacz, Kate AU - Hsu, Ling AU - Chen, Miao-Jung AU - Selik, Richard M AU - Rose, Charles AU - Williams, Tiffany AU - Brooks, John T AU - Schwarcz, Sandra AD - Division of HIV/AIDS Prevention, kdjawe@cdc.gov Y1 - 2015/11/01/ PY - 2015 DA - 2015 Nov 01 SP - 1366 EP - 1375 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 212 IS - 9 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - AIDS KW - AIDS-defining illness KW - mortality KW - HIV KW - survival KW - Mortality KW - Acquired immune deficiency syndrome KW - Data processing KW - Pneumocystis KW - Brain KW - Survival KW - Progressive multifocal leukoencephalopathy KW - Models KW - Prevention KW - Infectious diseases KW - Human immunodeficiency virus KW - Risk factors KW - Sarcoma KW - INE, USA, California, San Francisco KW - Lymphoma KW - Pneumonia KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - V 22360:AIDS and HIV UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1776654352?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Mortality+Risk+After+AIDS-Defining+Opportunistic+Illness+Among+HIV-Infected+Persons-San+Francisco%2C+1981-2012&rft.au=Djawe%2C+Kpandja%3BBuchacz%2C+Kate%3BHsu%2C+Ling%3BChen%2C+Miao-Jung%3BSelik%2C+Richard+M%3BRose%2C+Charles%3BWilliams%2C+Tiffany%3BBrooks%2C+John+T%3BSchwarcz%2C+Sandra&rft.aulast=Djawe&rft.aufirst=Kpandja&rft.date=2015-11-01&rft.volume=212&rft.issue=9&rft.spage=1366&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiv235 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-03-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Mortality; Acquired immune deficiency syndrome; Data processing; Risk factors; Sarcoma; Brain; Survival; Progressive multifocal leukoencephalopathy; Lymphoma; Pneumonia; Models; Prevention; Infectious diseases; Human immunodeficiency virus; Pneumocystis; INE, USA, California, San Francisco DO - http://dx.doi.org/10.1093/infdis/jiv235 ER - TY - JOUR T1 - Staphylococcus aureus Colonization and Strain Type at Various Body Sites among Patients with a Closed Abscess and Uninfected Controls at U.S. Emergency Departments AN - 1751215332; PQ0002308805 AB - Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is a prevalent cause of skin and soft tissue infections (SSTI), but the association between CA-MRSA colonization and infection remains uncertain. We studied the carriage frequency at several body sites and the diversity of S. aureus strains from patients with and without SSTI. Specimens from the nares, throat, rectum, and groin of case subjects with a closed skin abscess (i.e., without drainage) and matched control subjects without a skin infection (n = 147 each) presenting to 10 U.S. emergency departments were cultured using broth enrichment; wound specimens were cultured from abscess cases. Methicillin resistance testing and spa typing were performed for all S. aureus isolates. S. aureus was found in 85/147 (57.8%) of abscesses; 49 isolates were MRSA, and 36 were methicillin-susceptible S. aureus (MSSA). MRSA colonization was more common among cases (59/147; 40.1%) than among controls (27/147; 18.4%) overall (P < 0.001) and at each body site; no differences were observed for MSSA. S. aureus-infected subjects were usually (75/85) colonized with the infecting strain; among MRSA-infected subjects, this was most common in the groin. The CC8 lineage accounted for most of both infecting and colonizing isolates, although more than 16 distinct strains were identified. Nearly all MRSA infections were inferred to be USA300. There was more diversity among colonizing than infecting isolates and among those isolated from controls versus cases. CC8 S. aureus is a common colonizer of persons with and without skin infections. Detection of S. aureus colonization, and especially MRSA, may be enhanced by extranasal site culture. JF - Journal of Clinical Microbiology AU - Albrecht, Valerie S AU - Limbago, Brandi M AU - Moran, Gregory J AU - Krishnadasan, Anusha AU - Gorwitz, Rachel J AU - McDougal, Linda K AU - Talan, David A AD - << + $0, BBL7@cdc.gov. Y1 - 2015/11// PY - 2015 DA - November 2015 SP - 3478 EP - 3484 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 53 IS - 11 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Skin KW - Rectum KW - Pharynx KW - Drug resistance KW - Drainage KW - Infection KW - Abscesses KW - Wounds KW - Colonization KW - Typing KW - Methicillin KW - Staphylococcus aureus KW - Soft tissues KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1751215332?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Staphylococcus+aureus+Colonization+and+Strain+Type+at+Various+Body+Sites+among+Patients+with+a+Closed+Abscess+and+Uninfected+Controls+at+U.S.+Emergency+Departments&rft.au=Albrecht%2C+Valerie+S%3BLimbago%2C+Brandi+M%3BMoran%2C+Gregory+J%3BKrishnadasan%2C+Anusha%3BGorwitz%2C+Rachel+J%3BMcDougal%2C+Linda+K%3BTalan%2C+David+A&rft.aulast=Albrecht&rft.aufirst=Valerie&rft.date=2015-11-01&rft.volume=53&rft.issue=11&rft.spage=3478&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.01371-15 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-12-01 N1 - Number of references - 31 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Colonization; Pharynx; Methicillin; Rectum; Typing; Skin; Drainage; Drug resistance; Abscesses; Infection; Soft tissues; Wounds; Staphylococcus aureus DO - http://dx.doi.org/10.1128/JCM.01371-15 ER - TY - GEN T1 - Editorial utility of population-based birth defects surveillance for monitoring the health of infants and as a foundation for etiologic research. AN - 1737477655; 26458078 JF - Birth defects research. Part A, Clinical and molecular teratology AU - Moore, Cynthia A AU - McCabe, Edward R B Y1 - 2015/11// PY - 2015 DA - November 2015 SP - 895 EP - 898 VL - 103 IS - 11 KW - Index Medicus KW - Infant KW - Humans KW - United States -- epidemiology KW - Biomedical Research KW - Health Status KW - Congenital Abnormalities -- epidemiology KW - Congenital Abnormalities -- etiology KW - Population Surveillance -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1737477655?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=Birth+defects+research.+Part+A%2C+Clinical+and+molecular+teratology&rft.atitle=Editorial+utility+of+population-based+birth+defects+surveillance+for+monitoring+the+health+of+infants+and+as+a+foundation+for+etiologic+research.&rft.au=Moore%2C+Cynthia+A%3BMcCabe%2C+Edward+R+B&rft.aulast=Moore&rft.aufirst=Cynthia&rft.date=2015-11-01&rft.volume=103&rft.issue=11&rft.spage=895&rft.isbn=&rft.btitle=&rft.title=Birth+defects+research.+Part+A%2C+Clinical+and+molecular+teratology&rft.issn=1542-0760&rft_id=info:doi/10.1002%2Fbdra.23421 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2016-09-13 N1 - Date created - 2015-11-27 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Cited By: Am J Public Health. 2005 Nov;95(11):1884-6 [16195507] Birth Defects Res A Clin Mol Teratol. 2007 Feb;79(2):65-186 [17278144] PLoS One. 2013;8(7):e69077 [23874873] Pediatrics. 2013 Jan;131(1):e27-36 [23248222] MMWR Suppl. 2012 Jul 27;61(3):20-4 [22832993] MMWR Suppl. 2012 Jul 27;61(3):3-9 [22832990] Neurology. 2012 Jun 5;78(23):1886-91 [22665145] J Pediatr. 2012 Jun;160(6):978-83 [22244463] Arch Pediatr Adolesc Med. 2012 Feb;166(2):121-6 [21969361] Am J Prev Med. 2011 May;40(5 Suppl 2):S154-8 [21521589] Am J Obstet Gynecol. 2011 Apr;204(4):314.e1-11 [21345403] Birth Defects Res A Clin Mol Teratol. 2009 Nov;85(11):925-34 [19830851] Birth Defects Res A Clin Mol Teratol. 2015 Aug;103(8):656-69 [26033852] Birth Defects Res A Clin Mol Teratol. 2015 Aug;103(8):733-40 [25846741] J Epidemiol Community Health. 2015 Jul;69(7):693-9 [25805603] J Pediatr. 2015 Apr;166(4):819-26.e1-2 [25641238] Birth Defects Res A Clin Mol Teratol. 2015 Feb;103(2):127-43 [25721952] Am J Emerg Med. 2014 Nov;32(11):1417 [25200509] Birth Defects Res A Clin Mol Teratol. 2014 Nov;100(11):837-47 [25200965] Milbank Q. 2014 Mar;92(1):7-33 [24597553] Birth Defects Res A Clin Mol Teratol. 2013 Oct;97(10):685-95 [24039055] J Med Internet Res. 2013;15(7):e147 [23896182] Arch Pediatr Adolesc Med. 2007 Aug;161(8):745-50 [17679655] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1002/bdra.23421 ER - TY - CPAPER T1 - Clinical presentation of pregnant women at isolation centers for Ebola Virus Disease in Sierra Leone, 2014 T2 - 143rd American Public Health Association Annual Meeting and Exposition (APHA 2015) AN - 1731771059; 6365487 JF - 143rd American Public Health Association Annual Meeting and Exposition (APHA 2015) AU - Johnson, Jonetta AU - Callaghan, William AU - Elamin, Hayfa AU - Ellington, Sascha AU - Kargbo, Samuel AU - Koroma, Alimamy AU - Lyman, Meghan AU - Morof, Diane AU - Soud, Fatma Y1 - 2015/10/31/ PY - 2015 DA - 2015 Oct 31 KW - Viruses KW - Sierra Leone KW - Pregnancy KW - Ebola virus UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1731771059?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+STD+%26+AIDS&rft.atitle=Use+of+expedited+partner+therapy+among+chlamydia+cases+diagnosed+at+an+urban+Indian+health+centre%2C+Arizona&rft.au=Taylor%2C+M+M%3BReilley%2C+B%3BYellowman%2C+M%3BAnderson%2C+L%3Bde+Ravello%2C+L%3BTulloch%2C+S&rft.aulast=Taylor&rft.aufirst=M&rft.date=2013-05-01&rft.volume=24&rft.issue=5&rft.spage=371&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+STD+%26+AIDS&rft.issn=09564624&rft_id=info:doi/10.1177%2F0956462412472825 L2 - https://apha.confex.com/apha/143am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-11-06 N1 - Last updated - 2015-11-09 ER - TY - CPAPER T1 - Strategic Risk Communication in a Black Swan Event T2 - 143rd American Public Health Association Annual Meeting and Exposition (APHA 2015) AN - 1731770918; 6365386 JF - 143rd American Public Health Association Annual Meeting and Exposition (APHA 2015) AU - Telfer, Jana AU - Said, Jonathan AU - Olivares, Dagny Y1 - 2015/10/31/ PY - 2015 DA - 2015 Oct 31 KW - Communication UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1731770918?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=143rd+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2015%29&rft.atitle=Strategic+Risk+Communication+in+a+Black+Swan+Event&rft.au=Telfer%2C+Jana%3BSaid%2C+Jonathan%3BOlivares%2C+Dagny&rft.aulast=Telfer&rft.aufirst=Jana&rft.date=2015-10-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=143rd+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2015%29&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/143am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-11-06 N1 - Last updated - 2015-11-09 ER - TY - CPAPER T1 - Order amid Chaos: Structuring communication functions to amplify effectiveness in Ebola Time T2 - 143rd American Public Health Association Annual Meeting and Exposition (APHA 2015) AN - 1731770731; 6365383 JF - 143rd American Public Health Association Annual Meeting and Exposition (APHA 2015) AU - Telfer, Jana AU - Olivares, Dagny Y1 - 2015/10/31/ PY - 2015 DA - 2015 Oct 31 KW - Viruses KW - Communication KW - Chaos theory UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1731770731?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=143rd+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2015%29&rft.atitle=Order+amid+Chaos%3A+Structuring+communication+functions+to+amplify+effectiveness+in+Ebola+Time&rft.au=Telfer%2C+Jana%3BOlivares%2C+Dagny&rft.aulast=Telfer&rft.aufirst=Jana&rft.date=2015-10-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=143rd+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2015%29&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/143am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-11-06 N1 - Last updated - 2015-11-09 ER - TY - CPAPER T1 - Assessment of ICD-9-CM Codes included in the CDC's Definition of a Traumatic Brain Injury T2 - 143rd American Public Health Association Annual Meeting and Exposition (APHA 2015) AN - 1731768221; 6366568 JF - 143rd American Public Health Association Annual Meeting and Exposition (APHA 2015) AU - Haarbauer-Krupa, Juliet AU - Hirsch, Shawn AU - Coronado, Victor AU - Valdes, Raydel AU - Lowe, Brooks AU - Register-Mihalik, Johna Y1 - 2015/10/31/ PY - 2015 DA - 2015 Oct 31 KW - Brain KW - Traumatic brain injury UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1731768221?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=143rd+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2015%29&rft.atitle=Assessment+of+ICD-9-CM+Codes+included+in+the+CDC%27s+Definition+of+a+Traumatic+Brain+Injury&rft.au=Haarbauer-Krupa%2C+Juliet%3BHirsch%2C+Shawn%3BCoronado%2C+Victor%3BValdes%2C+Raydel%3BLowe%2C+Brooks%3BRegister-Mihalik%2C+Johna&rft.aulast=Haarbauer-Krupa&rft.aufirst=Juliet&rft.date=2015-10-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=143rd+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2015%29&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/143am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-11-06 N1 - Last updated - 2015-11-09 ER - TY - CPAPER T1 - Ebola Must GO: Stopping Ebola is Everybody's Business T2 - 143rd American Public Health Association Annual Meeting and Exposition (APHA 2015) AN - 1731764861; 6367738 JF - 143rd American Public Health Association Annual Meeting and Exposition (APHA 2015) AU - Telfer, Jana AU - Harrington, Peter AU - Douglas, Stephen AU - Huebner, Nathan AU - Warren, Felicia Y1 - 2015/10/31/ PY - 2015 DA - 2015 Oct 31 KW - Viruses UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1731764861?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=143rd+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2015%29&rft.atitle=Ebola+Must+GO%3A+Stopping+Ebola+is+Everybody%27s+Business&rft.au=Telfer%2C+Jana%3BHarrington%2C+Peter%3BDouglas%2C+Stephen%3BHuebner%2C+Nathan%3BWarren%2C+Felicia&rft.aulast=Telfer&rft.aufirst=Jana&rft.date=2015-10-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=143rd+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2015%29&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/143am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-11-06 N1 - Last updated - 2015-11-09 ER - TY - CPAPER T1 - Sandbox Play: CDC's Prevention Research Centers' partnerships with health agencies in the context of core research project types and CDC's National Center for Chronic Disease Prevention and Health Promotion's priority domains T2 - 143rd American Public Health Association Annual Meeting and Exposition (APHA 2015) AN - 1731764686; 6367729 JF - 143rd American Public Health Association Annual Meeting and Exposition (APHA 2015) AU - Croston, Merriah Y1 - 2015/10/31/ PY - 2015 DA - 2015 Oct 31 KW - Prevention KW - Priorities KW - Governments KW - Health promotion UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1731764686?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=143rd+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2015%29&rft.atitle=Persistence+of+deposited+metals+in+the+lungs+after+stainless+steel+and+mild+steel+welding+fume+inhalation+in+rats.&rft.au=Antonini%2C+James+M%3BRoberts%2C+Jenny+R%3BStone%2C+Samuel%3BChen%2C+Bean+T%3BSchwegler-Berry%2C+Diane%3BChapman%2C+Rebecca%3BZeidler-Erdely%2C+Patti+C%3BAndrews%2C+Ronnee+N%3BFrazer%2C+David+G&rft.aulast=Antonini&rft.aufirst=James&rft.date=2011-05-01&rft.volume=85&rft.issue=5&rft.spage=487&rft.isbn=&rft.btitle=&rft.title=Archives+of+toxicology&rft.issn=1432-0738&rft_id=info:doi/10.1007%2Fs00204-010-0601-1 L2 - https://apha.confex.com/apha/143am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-11-06 N1 - Last updated - 2015-11-09 ER - TY - CPAPER T1 - Oral Health Status of Adults aged >= 40 years with Vision Impairment or Eye Diseases: Findings from the National Health Interview Survey, 2008 T2 - 143rd American Public Health Association Annual Meeting and Exposition (APHA 2015) AN - 1731763772; 6366003 JF - 143rd American Public Health Association Annual Meeting and Exposition (APHA 2015) AU - Crews, John AU - Chou, Chiu-Fang AU - Saaddine, Jinan AU - Naavaal, Shillpa Y1 - 2015/10/31/ PY - 2015 DA - 2015 Oct 31 KW - Vision KW - Eye diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1731763772?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=143rd+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2015%29&rft.atitle=Oral+Health+Status+of+Adults+aged+%26gt%3B%3D+40+years+with+Vision+Impairment+or+Eye+Diseases%3A+Findings+from+the+National+Health+Interview+Survey%2C+2008&rft.au=Crews%2C+John%3BChou%2C+Chiu-Fang%3BSaaddine%2C+Jinan%3BNaavaal%2C+Shillpa&rft.aulast=Crews&rft.aufirst=John&rft.date=2015-10-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=143rd+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2015%29&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/143am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-11-06 N1 - Last updated - 2015-11-09 ER - TY - CPAPER T1 - Are the Associations between Adverse Childhood Experiences and Chronic Diseases Stronger in Women than in Men? T2 - 143rd American Public Health Association Annual Meeting and Exposition (APHA 2015) AN - 1731760381; 6367175 JF - 143rd American Public Health Association Annual Meeting and Exposition (APHA 2015) AU - Cunningham, Timothy AU - Ford, Earl AU - Wheaton, Anne AU - Merrick, Melissa AU - Croft, Janet AU - Giles, Wayne Y1 - 2015/10/31/ PY - 2015 DA - 2015 Oct 31 KW - Children UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1731760381?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=143rd+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2015%29&rft.atitle=Are+the+Associations+between+Adverse+Childhood+Experiences+and+Chronic+Diseases+Stronger+in+Women+than+in+Men%3F&rft.au=Cunningham%2C+Timothy%3BFord%2C+Earl%3BWheaton%2C+Anne%3BMerrick%2C+Melissa%3BCroft%2C+Janet%3BGiles%2C+Wayne&rft.aulast=Cunningham&rft.aufirst=Timothy&rft.date=2015-10-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=143rd+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2015%29&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/143am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-11-06 N1 - Last updated - 2015-11-09 ER - TY - CPAPER T1 - Causes of Death among Patients with Bleeding Disorders Receiving Care at US Hemophilia Treatment Centers, October 2011-December 2014 T2 - 143rd American Public Health Association Annual Meeting and Exposition (APHA 2015) AN - 1731760371; 6366758 JF - 143rd American Public Health Association Annual Meeting and Exposition (APHA 2015) AU - Oakley, Meredith Y1 - 2015/10/31/ PY - 2015 DA - 2015 Oct 31 KW - Mortality KW - Bleeding KW - Hemophilia UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1731760371?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=143rd+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2015%29&rft.atitle=Causes+of+Death+among+Patients+with+Bleeding+Disorders+Receiving+Care+at+US+Hemophilia+Treatment+Centers%2C+October+2011-December+2014&rft.au=Oakley%2C+Meredith&rft.aulast=Oakley&rft.aufirst=Meredith&rft.date=2015-10-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=143rd+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2015%29&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/143am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-11-06 N1 - Last updated - 2015-11-09 ER - TY - CPAPER T1 - Knowledge, Attitudes, and Beliefs Related to Hypertension and High Cholesterol Self-Management among African American Men living in the Southeastern United States T2 - 143rd American Public Health Association Annual Meeting and Exposition (APHA 2015) AN - 1731760302; 6366913 JF - 143rd American Public Health Association Annual Meeting and Exposition (APHA 2015) AU - Long, Everett AU - Ponder, Monica AU - Bernard, Stephanie AU - Lane, Rashon Y1 - 2015/10/31/ PY - 2015 DA - 2015 Oct 31 KW - Attitudes KW - Cholesterol KW - USA, Southeast KW - Ethnic groups KW - Hypertension UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1731760302?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=143rd+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2015%29&rft.atitle=Knowledge%2C+Attitudes%2C+and+Beliefs+Related+to+Hypertension+and+High+Cholesterol+Self-Management+among+African+American+Men+living+in+the+Southeastern+United+States&rft.au=Long%2C+Everett%3BPonder%2C+Monica%3BBernard%2C+Stephanie%3BLane%2C+Rashon&rft.aulast=Long&rft.aufirst=Everett&rft.date=2015-10-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=143rd+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2015%29&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/143am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-11-06 N1 - Last updated - 2015-11-09 ER - TY - CPAPER T1 - Integrating Pharmacies into Pandemic Influenza Vaccine Response Planning T2 - 143rd American Public Health Association Annual Meeting and Exposition (APHA 2015) AN - 1731760021; 6364727 JF - 143rd American Public Health Association Annual Meeting and Exposition (APHA 2015) AU - Fitzgerald, Thomas AU - Graitcer, Samuel AU - Kang, Yoonjae Y1 - 2015/10/31/ PY - 2015 DA - 2015 Oct 31 KW - Influenza KW - pandemics KW - Disease control KW - Vaccines UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1731760021?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Clam-associated+vibriosis%2C+USA%2C+1988-2010&rft.au=Slayton%2C+R+B%3BNewton%2C+A+E%3BDepaola%2C+A%3BJones%2C+J+L%3BMahon%2C+B+E&rft.aulast=Slayton&rft.aufirst=R&rft.date=2014-05-01&rft.volume=142&rft.issue=5&rft.spage=1083&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268813001830 L2 - https://apha.confex.com/apha/143am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-11-06 N1 - Last updated - 2015-11-09 ER - TY - JOUR T1 - Emergence of Multidrug-Resistant Influenza A(H1N1)pdm09 Virus Variants in an Immunocompromised Child Treated With Oseltamivir and Zanamivir AN - 1773859747; PQ0002721034 AB - Prolonged treatment of an immunocompromised child with oseltamivir and zanamivir for A(H1N1)pdm09 virus infection led to the emergence of viruses carrying H275Y and/or E119G in the neuraminidase (NA). When phenotypically evaluated by NA inhibition, the dual H275Y-E119G substitution caused highly reduced inhibition by 4 NA inhibitors: oseltamivir, zanamivir, peramivir, and laninamivir. JF - Journal of Infectious Diseases AU - Tamura, Daisuke AU - Debiasi, Roberta L AU - Okomo-Adhiambo, Margaret AU - Mishin, Vasiliy P AU - Campbell, Angela P AU - Loechelt, Brett AU - Wiedermann, Bernhard L AU - Fry, Alicia M AU - Gubareva, Larisa V AD - Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, lgubareva@cdc.gov Y1 - 2015/10/15/ PY - 2015 DA - 2015 Oct 15 SP - 1209 EP - 1213 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 212 IS - 8 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - neuraminidase KW - drug resistance KW - pyrosequencing KW - oseltamivir KW - zanamivir KW - Influenza KW - Infectious diseases KW - Drug resistance KW - Viruses KW - Exo- alpha -sialidase KW - Infection KW - Zanamivir KW - Oseltamivir KW - H 0500:General KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1773859747?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Emergence+of+Multidrug-Resistant+Influenza+A%28H1N1%29pdm09+Virus+Variants+in+an+Immunocompromised+Child+Treated+With+Oseltamivir+and+Zanamivir&rft.au=Tamura%2C+Daisuke%3BDebiasi%2C+Roberta+L%3BOkomo-Adhiambo%2C+Margaret%3BMishin%2C+Vasiliy+P%3BCampbell%2C+Angela+P%3BLoechelt%2C+Brett%3BWiedermann%2C+Bernhard+L%3BFry%2C+Alicia+M%3BGubareva%2C+Larisa+V&rft.aulast=Tamura&rft.aufirst=Daisuke&rft.date=2015-10-15&rft.volume=212&rft.issue=8&rft.spage=1209&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiv245 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-03-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Influenza; Drug resistance; Exo- alpha -sialidase; Infection; Zanamivir; Oseltamivir; Infectious diseases; Viruses DO - http://dx.doi.org/10.1093/infdis/jiv245 ER - TY - JOUR T1 - Relationship Between Ebola Virus Real-Time Quantitative Polymerase Chain Reaction-Based Threshold Cycle Value and Virus Isolation From Human Plasma AN - 1780502787; PQ0002879716 AB - We performed a longitudinal analysis of plasma samples obtained from 4 patients with Ebola virus (EBOV) disease (EVD) to determine the relationship between the real-time quantitative reverse transcriptase polymerase chain reaction (qRT-PCR)-based threshold cycle (Ct) value and the presence of infectious EBOV. EBOV was not isolated from plasma samples with a Ct value of >35.5 or >12 days after onset of symptoms. EBOV was not isolated from plasma samples in which anti-EBOV nucleoprotein immunoglobulin G was detected. These data demonstrate the utility of interpreting qRT-PCR results in the context of the course of EBOV infection and associated serological responses for patient-management decisions. JF - Journal of Infectious Diseases AU - Spengler, Jessica R AU - McElroy, Anita K AU - Harmon, Jessica R AU - Stroher, Ute AU - Nichol, Stuart T AU - Spiropoulou, Christina F AD - Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, ccs8@cdc.gov Y1 - 2015/10/01/ PY - 2015 DA - 2015 Oct 01 SP - S346 EP - S349 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 212 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Ebola KW - qRT-PCR KW - virus isolation KW - Data processing KW - Infectious diseases KW - Viruses KW - Nucleoproteins KW - Immunoglobulin G KW - RNA-directed DNA polymerase KW - Polymerase chain reaction KW - Ebola virus KW - Infection KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1780502787?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Relationship+Between+Ebola+Virus+Real-Time+Quantitative+Polymerase+Chain+Reaction-Based+Threshold+Cycle+Value+and+Virus+Isolation+From+Human+Plasma&rft.au=Spengler%2C+Jessica+R%3BMcElroy%2C+Anita+K%3BHarmon%2C+Jessica+R%3BStroher%2C+Ute%3BNichol%2C+Stuart+T%3BSpiropoulou%2C+Christina+F&rft.aulast=Spengler&rft.aufirst=Jessica&rft.date=2015-10-01&rft.volume=212&rft.issue=&rft.spage=S346&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiv187 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-04-01 N1 - Last updated - 2016-08-03 N1 - SubjectsTermNotLitGenreText - Data processing; Nucleoproteins; Immunoglobulin G; Polymerase chain reaction; RNA-directed DNA polymerase; Infection; Infectious diseases; Viruses; Ebola virus DO - http://dx.doi.org/10.1093/infdis/jiv187 ER - TY - JOUR T1 - Multidistrict Outbreak of Marburg Virus DiseaseemdashUganda, 2012 AN - 1780498458; PQ0002879689 AB - In October 2012, a cluster of illnesses and deaths was reported in Uganda and was confirmed to be an outbreak of Marburg virus disease (MVD). Patients meeting the case criteria were interviewed using a standard investigation form, and blood specimens were tested for evidence of acute or recent Marburg virus infection by reverse transcription-polymerase chain reaction (RT-PCR) and antibody enzyme-linked immunosorbent assay. The total count of confirmed and probable MVD cases was 26, of which 15 (58%) were fatal. Four of 15 laboratory-confirmed cases (27%) were fatal. Case patients were located in 4 different districts in Uganda, although all chains of transmission originated in Ibanda District, and the earliest case detected had an onset in July 2012. No zoonotic exposures were identified. Symptoms significantly associated with being a MVD case included hiccups, anorexia, fatigue, vomiting, sore throat, and difficulty swallowing. Contact with a case patient and attending a funeral were also significantly associated with being a case. Average RT-PCR cycle threshold values for fatal cases during the acute phase of illness were significantly lower than those for nonfatal cases. Following the institution of contact tracing, active case surveillance, care of patients with isolation precautions, community mobilization, and rapid diagnostic testing, the outbreak was successfully contained 14 days after its initial detection. JF - Journal of Infectious Diseases AU - Knust, Barbara AU - Schafer, Ilana J AU - Wamala, Joseph AU - Nyakarahuka, Luke AU - Okot, Charles AU - Shoemaker, Trevor AU - Dodd, Kimberly AU - Gibbons, Aridth AU - Balinandi, Stephen AU - Tumusiime, Alex AD - Viral Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, bknust@cdc.gov Y1 - 2015/10/01/ PY - 2015 DA - 2015 Oct 01 SP - S119 EP - S128 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 212 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Marburg virus KW - filoviruses KW - hemorrhagic fever KW - zoonotic disease KW - outbreak response KW - Mortality KW - swallowing KW - Enzyme-linked immunosorbent assay KW - Fatigue KW - Vomiting KW - Uganda KW - Pharyngitis KW - Infection KW - Contact tracing KW - Disease transmission KW - Blood KW - Antibodies KW - Infectious diseases KW - anorexia KW - Polymerase chain reaction KW - Outbreaks KW - Immunoassays KW - H 0500:General KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1780498458?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Multidistrict+Outbreak+of+Marburg+Virus+DiseaseemdashUganda%2C+2012&rft.au=Knust%2C+Barbara%3BSchafer%2C+Ilana+J%3BWamala%2C+Joseph%3BNyakarahuka%2C+Luke%3BOkot%2C+Charles%3BShoemaker%2C+Trevor%3BDodd%2C+Kimberly%3BGibbons%2C+Aridth%3BBalinandi%2C+Stephen%3BTumusiime%2C+Alex&rft.aulast=Knust&rft.aufirst=Barbara&rft.date=2015-10-01&rft.volume=212&rft.issue=&rft.spage=S119&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiv351 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-04-01 N1 - Last updated - 2016-08-03 N1 - SubjectsTermNotLitGenreText - swallowing; Blood; Antibodies; Enzyme-linked immunosorbent assay; Vomiting; Fatigue; anorexia; Polymerase chain reaction; Pharyngitis; Contact tracing; Infection; Disease transmission; Mortality; Infectious diseases; Outbreaks; Immunoassays; Marburg virus; Uganda DO - http://dx.doi.org/10.1093/infdis/jiv351 ER - TY - JOUR T1 - Human Monkeypox in the Kivus, a Conflict Region of the Democratic Republic of the Congo AN - 1765987643; PQ0002617708 AB - Monkeypox (MPX) is a zoonotic Orthopoxvirus infection endemic in central and western Africa. Human MPX cases occur in the central and northern regions of the Democratic Republic of the Congo (DRC), and this is the first report of confirmed MPX cases in the forested areas of North and South Kivu Provinces, with a detailed epidemiological investigation for one case. The location of each case is within areas predicted to be suitable for MPX virus transmission based on an ecological niche model. Phylogenetic analysis places these viruses in the Congo Basin clade. JF - American Journal of Tropical Medicine and Hygiene AU - McCollum, Andrea M AU - Nakazawa, Yoshinori AU - Ndongala, Guy Mutombo AU - Pukuta, Elisabeth AU - Karhemere, Stomy AU - Lushima, Robert Shongo AU - Ilunga, Benoit Kebela AU - Kabamba, Joelle AU - Wilkins, Kimberly AU - Gao, Jinxin AD - Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, azv4@cdc.gov Y1 - 2015/10// PY - 2015 DA - October 2015 SP - 718 EP - 721 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 93 IS - 4 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Virology & AIDS Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts KW - Phylogeny KW - New records KW - Orthopoxvirus KW - Monkeypox KW - Ecological distribution KW - Niches KW - Viruses KW - Basins KW - Infection KW - Models KW - Disease transmission KW - Endemic species KW - Africa KW - Conflicts KW - Hygiene KW - Phylogenetics KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms KW - K 03310:Genetics & Taxonomy KW - V 22310:Genetics, Taxonomy & Structure UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1765987643?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Human+Monkeypox+in+the+Kivus%2C+a+Conflict+Region+of+the+Democratic+Republic+of+the+Congo&rft.au=McCollum%2C+Andrea+M%3BNakazawa%2C+Yoshinori%3BNdongala%2C+Guy+Mutombo%3BPukuta%2C+Elisabeth%3BKarhemere%2C+Stomy%3BLushima%2C+Robert+Shongo%3BIlunga%2C+Benoit+Kebela%3BKabamba%2C+Joelle%3BWilkins%2C+Kimberly%3BGao%2C+Jinxin&rft.aulast=McCollum&rft.aufirst=Andrea&rft.date=2015-10-01&rft.volume=93&rft.issue=4&rft.spage=718&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.15-0095 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - New records; Endemic species; Niches; Ecological distribution; Viruses; Hygiene; Phylogenetics; Disease transmission; Phylogeny; Monkeypox; Basins; Infection; Models; Conflicts; Orthopoxvirus; Africa DO - http://dx.doi.org/10.4269/ajtmh.15-0095 ER - TY - JOUR T1 - Border Lookout: Enhancing Tuberculosis Control on the United States-Mexico Border AN - 1765987445; PQ0002617713 AB - We evaluated the use of federal public health intervention tools known as the Do Not Board and Border Lookout (BL) for detecting and referring infectious or potentially infectious land border travelers with tuberculosis (TB) back to treatment. We used data about the issuance of BL from April 2007 to September 2013 to examine demographics and TB laboratory results for persons on the list (N = 66) and time on the list before being located and achieving noninfectious status. The majority of case-patients were Hispanic and male, with a median age of 39 years. Most were citizens of the United States or Mexico, and 30.3% were undocumented migrants. One-fifth had multidrug-resistant TB. Nearly two-thirds of case-patients were located and treated as a result of being placed on the list. However, 25.8% of case-patients, primarily undocumented migrants, remain lost to follow-up and remain on the list. For this highly mobile patient population, the use of this novel federal travel intervention tool facilitated the detection and treatment of infectious TB cases that were lost to follow-up. JF - American Journal of Tropical Medicine and Hygiene AU - DeSisto, Carla AU - Broussard, Kelly AU - Escobedo, Miguel AU - Borntrager, Denise AU - Alvarado-Ramy, Francisco AU - Waterman, Stephen AD - Division of Global Migration and Quarantine, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, carla.desisto@gmail.com Y1 - 2015/10// PY - 2015 DA - October 2015 SP - 747 EP - 751 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 93 IS - 4 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts KW - Travel KW - Age KW - Data processing KW - Mycobacterium KW - Drug resistance KW - Disease control KW - Intervention KW - Public health KW - Demography KW - USA KW - Mexico KW - Tuberculosis KW - Hygiene KW - International boundaries KW - Migrants KW - Ethnic groups KW - K 03400:Human Diseases KW - Q1 08485:Species interactions: pests and control KW - J 02400:Human Diseases KW - H 12000:Epidemiology and Public Health KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1765987445?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Border+Lookout%3A+Enhancing+Tuberculosis+Control+on+the+United+States-Mexico+Border&rft.au=DeSisto%2C+Carla%3BBroussard%2C+Kelly%3BEscobedo%2C+Miguel%3BBorntrager%2C+Denise%3BAlvarado-Ramy%2C+Francisco%3BWaterman%2C+Stephen&rft.aulast=DeSisto&rft.aufirst=Carla&rft.date=2015-10-01&rft.volume=93&rft.issue=4&rft.spage=747&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.15-0300 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Disease control; Tuberculosis; Hygiene; Public health; Travel; Demography; Age; Data processing; Drug resistance; Intervention; International boundaries; Ethnic groups; Migrants; Mycobacterium; USA; Mexico DO - http://dx.doi.org/10.4269/ajtmh.15-0300 ER - TY - JOUR T1 - A farewell to didanosine: harm reduction and cost savings by eliminating use of didanosine AN - 1765981547; PQ0002583996 AB - Didanosine (ddI) is a nucleoside reverse transcriptase inhibitor associated with adverse events and public health concerns which have diminished its place in HIV clinical practice, particularly in resource-rich settings. While international guidelines do not contain ddI-containing regimens in preferred first- or second-line antiretroviral therapy (ART), there is no guidance for management of patients currently on ddI. In 2012 at least 20 countries purchased a total of $1-2 million of ddI. Drug purchase data in that year show 3.2-10.3 times higher costs for ddI compared to lamivudine (3TC). Given issues of multiple toxicities, monitoring, drug interactions, inconvenience, and virologic efficacy, as well as cost and formulary concerns, national (including resource-limited setting) ART programmes should consider complete phase-out of ddI. JF - International Journal of STD & AIDS AU - Dziuban, Eric J AU - Raizes, Elliot AU - Koumans, Emilia H Y1 - 2015/10// PY - 2015 DA - October 2015 SP - 903 EP - 906 PB - Sage Publications, Inc., 2455 Teller Road Thousand Oaks CA 91320 United States VL - 26 IS - 12 SN - 0956-4624, 0956-4624 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Didanosine KW - HIV KW - AIDS KW - treatment KW - antiretroviral therapy KW - reverse transcriptase inhibitors KW - drug toxicity KW - drug interactions KW - Drug interaction KW - Acquired immune deficiency syndrome KW - Data processing KW - Guidelines KW - Lamivudine KW - Risk reduction KW - Toxicity KW - Antiretroviral agents KW - Public health KW - Human immunodeficiency virus KW - Drugs KW - Side effects KW - Sexually transmitted diseases KW - nucleoside reverse transcriptase inhibitors KW - V 22360:AIDS and HIV KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1765981547?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+STD+%26+AIDS&rft.atitle=A+farewell+to+didanosine%3A+harm+reduction+and+cost+savings+by+eliminating+use+of+didanosine&rft.au=Dziuban%2C+Eric+J%3BRaizes%2C+Elliot%3BKoumans%2C+Emilia+H&rft.aulast=Dziuban&rft.aufirst=Eric&rft.date=2015-10-01&rft.volume=26&rft.issue=12&rft.spage=903&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+STD+%26+AIDS&rft.issn=09564624&rft_id=info:doi/10.1177%2F0956462414554433 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Number of references - 28 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Drug interaction; Data processing; Didanosine; antiretroviral therapy; Lamivudine; Toxicity; Drugs; nucleoside reverse transcriptase inhibitors; Public health; Acquired immune deficiency syndrome; Human immunodeficiency virus; Guidelines; Risk reduction; Antiretroviral agents; Sexually transmitted diseases; Side effects DO - http://dx.doi.org/10.1177/0956462414554433 ER - TY - JOUR T1 - Use of random forest to estimate population attributable fractions from a case-control study of Salmonella enterica serotype Enteritidis infections AN - 1727687549; PQ0002023236 AB - To design effective food safety programmes we need to estimate how many sporadic foodborne illnesses are caused by specific food sources based on case-control studies. Logistic regression has substantive limitations for analysing structured questionnaire data with numerous exposures and missing values. We adapted random forest to analyse data of a case-control study of Salmonella enterica serotype Enteritidis illness for source attribution. For estimation of summary population attributable fractions (PAFs) of exposures grouped into transmission routes, we devised a counterfactual estimator to predict reductions in illness associated with removing grouped exposures. For the purpose of comparison, we fitted the data using logistic regression models with stepwise forward and backward variable selection. Our results show that the forward and backward variable selection of logistic regression models were not consistent for parameter estimation, with different significant exposures identified. By contrast, the random forest model produced estimated PAFs of grouped exposures consistent in rank order with results obtained from outbreak data, with egg-related exposures having the highest estimated PAF (22.1%, 95% confidence interval 8.5-31.8). Random forest might be structurally more coherent and efficient than logistic regression models for attributing Salmonella illnesses to sources involving many causal pathways. JF - Epidemiology and Infection AU - GU, W AU - Vieira, A R AU - Hoekstra, R M AU - Griffin, P M AU - Cole, D AD - Centers for Disease Control and Prevention, Enteric Diseases Epidemiology Branch, Atlanta, GA, USA, vhg8@cdc.gov Y1 - 2015/10// PY - 2015 DA - October 2015 SP - 2786 EP - 2794 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 143 IS - 13 SN - 0950-2688, 0950-2688 KW - Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts KW - Inventories KW - Data processing KW - Serotypes KW - Food KW - Forests KW - Food contamination KW - Pest outbreaks KW - Infection KW - Food-borne diseases KW - Models KW - Disease transmission KW - Platelet-activating factor KW - Salmonella enterica KW - Food sources KW - Regression analysis KW - Outbreaks KW - J 02400:Human Diseases KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727687549?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Use+of+random+forest+to+estimate+population+attributable+fractions+from+a+case-control+study+of+Salmonella+enterica+serotype+Enteritidis+infections&rft.au=GU%2C+W%3BVieira%2C+A+R%3BHoekstra%2C+R+M%3BGriffin%2C+P+M%3BCole%2C+D&rft.aulast=GU&rft.aufirst=W&rft.date=2015-10-01&rft.volume=143&rft.issue=13&rft.spage=2786&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS095026881500014X LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Number of references - 26 N1 - Last updated - 2016-03-30 N1 - SubjectsTermNotLitGenreText - Platelet-activating factor; Inventories; Serotypes; Data processing; Food; Food sources; Regression analysis; Forests; Infection; Pest outbreaks; Disease transmission; Models; Outbreaks; Food contamination; Food-borne diseases; Salmonella enterica DO - http://dx.doi.org/10.1017/S095026881500014X ER - TY - JOUR T1 - Pneumococcal vaccination coverage among persons greater than or equal to 65 years-United States, 2013 AN - 1727674728; PQ0002170063 AB - Background Invasive pneumococcal disease is a major cause of illness in the United States, and rates are higher among persons greater than or equal to 65 years. Pneumococcal vaccination has been recommended to adults greater than or equal to 65 years since 1997. Methods Data from the 2005-2013 Behavioral Risk Factor Surveillance System were analyzed. Weighted estimates of pneumococcal vaccination coverage were calculated by state and race/ethnicity and tests for linear trend were performed. Results In 2013, the median state vaccination coverage among adults greater than or equal to 65 years was 69.5%, and coverage ranged from 61.9% in New Jersey to 75.6% in Oregon. Coverage overall among non-Hispanic whites (71.1%) was higher than coverage for non-Hispanic blacks (57.7%), Hispanics (51.9%), and non-Hispanic persons of other race (65.4%). Coverage increased from 2005 to 2013 overall and by racial/ethnic subgroups. Conclusion Although pneumococcal vaccination coverage has improved in the past several years, coverage remains below the Healthy People 2020 target of 90% and racial/ethnic disparities exist. JF - Vaccine AU - O'Halloran, Alissa C AU - Lu, Peng-jun AU - Pilishvili, Tamara AD - Immunization Services Division, National Center for Immunization and Respiratory Diseases, CDC, 1600 Clifton Road, NE, Mail Stop A 19, Atlanta, GA 30329, United States Y1 - 2015/10// PY - 2015 DA - October 2015 SP - 5503 EP - 5506 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 33 IS - 42 SN - 0264-410X, 0264-410X KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Pneumococcal vaccination KW - Streptococcus pneumoniae KW - Data processing KW - Risk factors KW - Vaccination KW - Races KW - Ethnic groups KW - F 06905:Vaccines KW - J 02350:Immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727674728?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+journal+of+industrial+medicine&rft.atitle=Occupational+lung+cancer+in+US+women%2C+1984-1998.&rft.au=Robinson%2C+Cynthia+F%3BSullivan%2C+Patricia+A%3BLi%2C+Jia%3BWalker%2C+James+T&rft.aulast=Robinson&rft.aufirst=Cynthia&rft.date=2011-02-01&rft.volume=54&rft.issue=2&rft.spage=102&rft.isbn=&rft.btitle=&rft.title=American+journal+of+industrial+medicine&rft.issn=1097-0274&rft_id=info:doi/10.1002%2Fajim.20905 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Number of references - 20 N1 - Last updated - 2016-02-29 N1 - SubjectsTermNotLitGenreText - Data processing; Risk factors; Vaccination; Ethnic groups; Races; Streptococcus pneumoniae DO - http://dx.doi.org/10.1016/j.vaccine.2015.09.002 ER - TY - JOUR T1 - Network stigma towards people living with HIV/AIDS and their caregivers: an egocentric network study AN - 1721358545; 4713751 AB - HIV stigma occurs among peers in social networks. However, the features of social networks that drive HIV stigma are not well understood. The objective of this study is to investigate anticipated HIV stigma within the social networks of people living with HIV/AIDS (PLWHA) (N = 147) and the social networks of PLWHA's caregivers (N = 148). The egocentric social network data were collected in Guangxi, China. More than half of PLWHA (58%) and their caregivers (53%) anticipated HIV stigma from their network peers. Both PLWHA and their caregivers anticipated that spouses or other family members were less likely to stigmatise them, compared to friend peers or other relationships. Married network peers were believed to stigmatise caregivers more than unmarried peers. The association between frequent contacts and anticipated stigma was negative among caregivers. Being in a close relationship with PLWHA or caregivers (e.g., a spouse or other family member) was associated with less anticipated stigma. Lower network density was associated with higher anticipated stigma among PLWHA's alters, but not among caregivers' alters. Findings may shed light on innovative stigma reduction interventions at the social network level and therefore improve HIV/AIDS treatment utilisation. Reprinted by permission of Taylor & Francis Ltd. JF - Global public health AU - Wu, Fei AU - He, Xin AU - Guida, Jennifer AU - Xu, Yongfang AU - Liu, Hongjie AD - University of Maryland, College Park ; Nanning Center for Disease Control and Prevention Y1 - 2015/10// PY - 2015 DA - Oct 2015 SP - 1032 EP - 1045 VL - 10 IS - 9 SN - 1744-1692, 1744-1692 KW - Sociology KW - Social networks KW - Health care KW - Marital status KW - AIDS KW - Networks KW - HIV KW - Ego KW - Stigma KW - China KW - Public health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1721358545?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Global+public+health&rft.atitle=Network+stigma+towards+people+living+with+HIV%2FAIDS+and+their+caregivers%3A+an+egocentric+network+study&rft.au=Wu%2C+Fei%3BHe%2C+Xin%3BGuida%2C+Jennifer%3BXu%2C+Yongfang%3BLiu%2C+Hongjie&rft.aulast=Wu&rft.aufirst=Fei&rft.date=2015-10-01&rft.volume=10&rft.issue=9&rft.spage=1032&rft.isbn=&rft.btitle=&rft.title=Global+public+health&rft.issn=17441692&rft_id=info:doi/10.1080%2F17441692.2014.1003572 LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2015-10-12 N1 - Last updated - 2015-10-12 N1 - SubjectsTermNotLitGenreText - 5703 3617 6220; 12258 11762 11859 11856; 482 3617 6220; 4115; 8634; 7699 7748 6823; 11873 8634; 10449 5772; 5775 13521; 93 116 30 DO - http://dx.doi.org/10.1080/17441692.2014.1003572 ER - TY - JOUR T1 - Severe Acute Respiratory Illness Deaths in Sub-Saharan Africa and the Role of Influenza: A Case Series From 8 Countries AN - 1773833534; PQ0002695538 AB - Background. Data on causes of death due to respiratory illness in Africa are limited. Methods. From January to April 2013, 28 African countries were invited to participate in a review of severe acute respiratory illness (SARI)-associated deaths identified from influenza surveillance during 2009-2012. Results. Twenty-three countries (82%) responded, 11 (48%) collect mortality data, and 8 provided data. Data were collected from 37 714 SARI cases, and 3091 (8.2%; range by country, 5.1%-25.9%) tested positive for influenza virus. There were 1073 deaths (2.8%; range by country, 0.1%-5.3%) reported, among which influenza virus was detected in 57 (5.3%). Case-fatality proportion (CFP) was higher among countries with systematic death reporting than among those with sporadic reporting. The influenza-associated CFP was 1.8% (57 of 3091), compared with 2.9% (1016 of 34 623) for influenza virus-negative cases (P or =50 years. Conclusions. Few African countries systematically collect data on outcomes of people hospitalized with respiratory illness. Stronger surveillance for deaths due to respiratory illness may identify risk groups for targeted vaccine use and other prevention strategies. JF - Journal of Infectious Diseases AU - McMorrow, Meredith L AU - Wemakoy, Emile Okitolonda AU - Tshilobo, Joelle Kabamba AU - Emukule, Gideon O AU - Mott, Joshua A AU - Njuguna, Henry AU - Waiboci, Lilian AU - Heraud, Jean-Michel AU - Rajatonirina, Soatianana AU - Razanajatovo, Norosoa H AD - Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, mmcmorrow@cdc.gov Y1 - 2015/09/15/ PY - 2015 DA - 2015 Sep 15 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 212 IS - 6 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - influenza KW - human KW - mortality KW - Africa South of the Sahara KW - Mortality KW - Data processing KW - Influenza A KW - Adenovirus KW - Pathogens KW - Respiratory syncytial virus KW - Influenza KW - Streptococcus pneumoniae KW - Prevention KW - Influenza virus KW - Infectious diseases KW - Reviews KW - Africa KW - Risk groups KW - Rhinovirus KW - Vaccines KW - Hospitals KW - H 1000:Occupational Safety and Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1773833534?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Severe+Acute+Respiratory+Illness+Deaths+in+Sub-Saharan+Africa+and+the+Role+of+Influenza%3A+A+Case+Series+From+8+Countries&rft.au=McMorrow%2C+Meredith+L%3BWemakoy%2C+Emile+Okitolonda%3BTshilobo%2C+Joelle+Kabamba%3BEmukule%2C+Gideon+O%3BMott%2C+Joshua+A%3BNjuguna%2C+Henry%3BWaiboci%2C+Lilian%3BHeraud%2C+Jean-Michel%3BRajatonirina%2C+Soatianana%3BRazanajatovo%2C+Norosoa+H&rft.aulast=McMorrow&rft.aufirst=Meredith&rft.date=2015-09-15&rft.volume=212&rft.issue=6&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiv100 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-03-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Mortality; Data processing; Influenza A; Risk groups; Pathogens; Vaccines; Influenza; Prevention; Infectious diseases; Reviews; Hospitals; Respiratory syncytial virus; Streptococcus pneumoniae; Influenza virus; Adenovirus; Rhinovirus; Africa DO - http://dx.doi.org/10.1093/infdis/jiv100 ER - TY - JOUR T1 - Multinational Disease Surveillance Programs: Promoting Global Information Exchange for Infectious Diseases AN - 1827924434; PQ0003669087 AB - Cross-border surveillance for emerging diseases such as Ebola and other infectious diseases requires effective international collaboration. We surveyed representatives from 12 multinational disease surveillance programs between January 2013 and April 2014. Our survey identified programmatic similarities despite variation in health priorities, geography, and socioeconomic context, providing a contemporary perspective on infectious disease surveillance networks. JF - American Journal of Tropical Medicine and Hygiene AU - Varan, Aiden K AU - Bruniera-Oliveira, Robson AU - Peter, Christopher R AU - Fonseca-Ford, Maureen AU - Waterman, Stephen H AD - CDC/CSTE Applied Epidemiology Fellowship, Council of State and Territorial Epidemiologists, Atlanta, Georgia, shw2@cdc.gov Y1 - 2015/09// PY - 2015 DA - September 2015 SP - 668 EP - 671 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 93 IS - 3 SN - 0002-9637, 0002-9637 KW - Health & Safety Science Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Socio-economic aspects KW - Infectious diseases KW - Viruses KW - Socioeconomics KW - Priorities KW - Geography KW - International agreements KW - Information exchange KW - K 03490:Miscellaneous KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1827924434?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Multinational+Disease+Surveillance+Programs%3A+Promoting+Global+Information+Exchange+for+Infectious+Diseases&rft.au=Varan%2C+Aiden+K%3BBruniera-Oliveira%2C+Robson%3BPeter%2C+Christopher+R%3BFonseca-Ford%2C+Maureen%3BWaterman%2C+Stephen+H&rft.aulast=Varan&rft.aufirst=Aiden&rft.date=2015-09-01&rft.volume=93&rft.issue=3&rft.spage=668&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.15-0097 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-10-01 N1 - Last updated - 2016-10-26 N1 - SubjectsTermNotLitGenreText - Socio-economic aspects; Infectious diseases; Geography; Viruses; Priorities; Socioeconomics; International agreements; Information exchange DO - http://dx.doi.org/10.4269/ajtmh.15-0097 ER - TY - JOUR T1 - Medical and Indirect Costs Associated with a Rocky Mountain Spotted Fever Epidemic in Arizona, 2002-2011 AN - 1827886906; PQ0003669070 AB - Rocky Mountain spotted fever (RMSF) is an emerging public health issue on some American Indian reservations in Arizona. RMSF causes an acute febrile illness that, if untreated, can cause severe illness, permanent sequelae requiring lifelong medical support, and death. We describe costs associated with medical care, loss of productivity, and death among cases of RMSF on two American Indian reservations (estimated population 20,000) between 2002 and 2011. Acute medical costs totaled more than $1.3 million. This study further estimated $181,100 in acute productivity lost due to illness, and $11.6 million in lifetime productivity lost from premature death. Aggregate costs of RMSF cases in Arizona 2002-2011 amounted to $13.2 million. We believe this to be a significant underestimate of the cost of the epidemic, but it underlines the severity of the disease and need for a more comprehensive study. JF - American Journal of Tropical Medicine and Hygiene AU - Drexler, Naomi A AU - Traeger, Marc S AU - McQuiston, Jennifer H AU - Williams, Velda AU - Hamilton, Charlene AU - Regan, Joanna J AD - Rickettsial Zoonoses Branch, Division of Vector-borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, isj3@cdc.gov Y1 - 2015/09// PY - 2015 DA - September 2015 SP - 549 EP - 551 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 93 IS - 3 SN - 0002-9637, 0002-9637 KW - Health & Safety Science Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - North America, Rocky Mts. KW - Mountains KW - Mortality KW - Rocky Mountain spotted fever KW - Epidemics KW - Complications KW - USA, Arizona KW - Public health KW - K 03400:Human Diseases KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1827886906?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Medical+and+Indirect+Costs+Associated+with+a+Rocky+Mountain+Spotted+Fever+Epidemic+in+Arizona%2C+2002-2011&rft.au=Drexler%2C+Naomi+A%3BTraeger%2C+Marc+S%3BMcQuiston%2C+Jennifer+H%3BWilliams%2C+Velda%3BHamilton%2C+Charlene%3BRegan%2C+Joanna+J&rft.aulast=Drexler&rft.aufirst=Naomi&rft.date=2015-09-01&rft.volume=93&rft.issue=3&rft.spage=549&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.15-0104 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-10-01 N1 - Last updated - 2016-10-26 N1 - SubjectsTermNotLitGenreText - Rocky Mountain spotted fever; Epidemics; Complications; Public health; Mountains; Mortality; North America, Rocky Mts.; USA, Arizona DO - http://dx.doi.org/10.4269/ajtmh.15-0104 ER - TY - JOUR T1 - Three months of weekly rifapentine plus isoniazid is less hepatotoxic than nine months of daily isoniazid for LTBI AN - 1732810219; PQ0002041452 AB - SETTING: Nine months of daily isoniazid (9H) and 3 months of once-weekly rifapentine plus isoniazid (3HP) are recommended treatments for latent tuberculous infection (LTBI). The risk profile for 3HP and the contribution of hepatitis C virus (HCV) infection to hepatotoxicity are unclear. OBJECTIVES: To evaluate the hepatotoxicity risk associated with 3HP compared to 9H, and factors associated with hepatotoxicity DESIGN: Hepatotoxicity was defined as aspartate aminotransferase (AST) >3 times the upper limit of normal (ULN) with symptoms (nausea, vomiting, jaundice, or fatigue), or AST >5 x ULN. We analyzed risk factors among adults who took at least 1 dose of their assigned treatment. A nested case-control study assessed the role of HCV. RESULTS: Of 6862 participants, 77 (1.1%) developed hepatotoxicity; 52 (0.8%) were symptomatic; 1.8% (61/3317) were on 9H and 0.4% (15/3545) were on 3HP (P < 0.0001). Risk factors for hepatotoxicity were age, female sex, white race, non-Hispanic ethnicity, decreased body mass index, elevated baseline AST, and 9H. In the case-control study, HCV infection was associated with hepatotoxicity when controlling for other factors. CONCLUSION: The risk of hepatotoxicity during LTBI treatment with 3HP was lower than the risk with 9H. HCV and elevated baseline AST were risk factors for hepatotoxicity. For persons with these risk factors, 3HP may be preferred. JF - International Journal of Tuberculosis and Lung Disease AU - Bliven-Sizemore, E E AU - Sterling, T R AU - Shang, N AU - Benator, D AU - Schwartzman, K AU - Reves, R AU - Drobeniuc, J AU - Bock, N AU - Villarino, M E AD - Division of Tuberculosis Elimination, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, esizemore@cdc.gov PY - 2015 SP - 1039 EP - 1044 PB - International Union Against Tuberculosis and Lung Disease, 68 bvd Saint-Michel Paris 75006 France VL - 19 IS - 9 SN - 1027-3719, 1027-3719 KW - Health & Safety Science Abstracts; Risk Abstracts KW - isoniazid KW - hepatitis C KW - aspartate aminotransferases KW - Risk assessment KW - Age KW - Fatigue KW - Mycobacterium KW - Body mass KW - Infection KW - Lung KW - Risk factors KW - Tuberculosis KW - Hepatitis C KW - Hepatotoxicity KW - Ethnic groups KW - R2 23060:Medical and environmental health KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1732810219?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Three+months+of+weekly+rifapentine+plus+isoniazid+is+less+hepatotoxic+than+nine+months+of+daily+isoniazid+for+LTBI&rft.au=Bliven-Sizemore%2C+E+E%3BSterling%2C+T+R%3BShang%2C+N%3BBenator%2C+D%3BSchwartzman%2C+K%3BReves%2C+R%3BDrobeniuc%2C+J%3BBock%2C+N%3BVillarino%2C+M+E&rft.aulast=Bliven-Sizemore&rft.aufirst=E&rft.date=2015-09-01&rft.volume=19&rft.issue=9&rft.spage=1039&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/10.5588%2Fijtld.14.0829 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-11-01 N1 - Last updated - 2015-12-23 N1 - SubjectsTermNotLitGenreText - Risk assessment; Age; Fatigue; Lung; Body mass; Risk factors; Tuberculosis; Hepatitis C; Infection; Hepatotoxicity; Ethnic groups; Mycobacterium DO - http://dx.doi.org/10.5588/ijtld.14.0829 ER - TY - JOUR T1 - Comparison of the deratization effect between two methods of poison bait box and scattered poison bait AN - 1842511740; PQ0002658850 AB - The objective of this paper is to compare the deratization effect between two methods of poison bait box and scattered poison bait. The field tests were carried out in Sujia, Guo jia, Xicaishi, Guoheitun and Liuheitun village of Linyi city and Jinan city. In Sujia villageone box with 0.05% diphacine-Na bait was placed in every two rooms; while in Guojia village, the bait was scattered in every room. In Xicaishi village, one box with 0.05% diphacine-Na wheat was placed in every room. In Guoheitun and Liuhei tun villages, 3-5 piles of 0.05% diphacine-Na mixed poison baits poison bait weighted 5-10 g were scattered in every room for four days. The powder p late method was employed to evaluate the deratization effect. The method of poison bait box is an important technical means on the sustainable control of population density of rodents. JF - Chinese Journal of Hygienic Insecticides & Equipment AU - Gong, Xue-shi AU - Liu, Yong AU - Qu, Bao-quan AU - Zhang, Shi-shui AU - Jing, Xiao AU - Wang, Xue-jun AU - Liu, Feng AU - Zhao, Zhi-gang AU - Fu, Ying AU - Zhang, Kui-wei AD - Shandong Provincial Center for Disease Control and Prevention Y1 - 2015/08// PY - 2015 DA - August 2015 PB - Editorial Department of the Chinese Journal of Hygienic Insecticides & Equipment, 293 Zhongshan East Road Nanjing, Jiangsu Province, 210002 China VL - 21 IS - 4 SN - 1671-2781, 1671-2781 KW - Toxicology Abstracts KW - poison bait box method KW - scattered poison bai method KW - diphacine-Na KW - deratization effect KW - Triticum aestivum KW - Powder KW - Insecticides KW - Population density KW - Hygiene KW - X 24330:Agrochemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1842511740?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chinese+Journal+of+Hygienic+Insecticides+%26+Equipment&rft.atitle=Comparison+of+the+deratization+effect+between+two+methods+of+poison+bait+box+and+scattered+poison+bait&rft.au=Gong%2C+Xue-shi%3BLiu%2C+Yong%3BQu%2C+Bao-quan%3BZhang%2C+Shi-shui%3BJing%2C+Xiao%3BWang%2C+Xue-jun%3BLiu%2C+Feng%3BZhao%2C+Zhi-gang%3BFu%2C+Ying%3BZhang%2C+Kui-wei&rft.aulast=Gong&rft.aufirst=Xue-shi&rft.date=2015-08-01&rft.volume=21&rft.issue=4&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Chinese+Journal+of+Hygienic+Insecticides+%26+Equipment&rft.issn=16712781&rft_id=info:doi/ LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-11-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Powder; Insecticides; Population density; Hygiene; Triticum aestivum ER - TY - JOUR T1 - Investigation and analysis of important medical vectors and vector-borne diseases in military camps in Shandong AN - 1768577370; PQ0002658873 AB - Objective To investigate the population density of important medical vectors and the potential of vectorborne diseases in military camps in Shandong. Methods Population density investigating of rodent, mosquitoes, flies and cockroaches was carried out based on the book "Disinsection and Deratization". Risk evaluation of vectorborne diseases was carried out according to investigating results. Results The captured rodentia belonged to 9 species, 5 genus, 3 families; mosquitoes 19 species, 5 genus; flies 122 species, 50 genus, 4 families; cockroaches 3 species. Rattus Norvegicus was the dominant species of rodent. The highest rodent density appeared in the hotels. Anopheles sinensis, Culex pipiens pallens and Aedes Albopictus existed in all camps investigated. Blattela germanica was the dominant cockroach species. Seven vector-borne diseases occured from 2005, and hemorrhagic fever with renal syndrome, malaria and inundation fever were the top three. Conclusion The risk of hemorrhagic fever with renal syndrome is high in camps of rural. JF - Chinese Journal of Hygienic Insecticides & Equipment AU - Zhou, Guang-zhi AU - Wen, Yu AU - Liu, Yuan-dong AU - Huang, Wei-chu AU - Wang, Zhi AU - He, Ying AU - Yin, Guang-qing AD - Center for Disease Control and Prevention of Jinan Command Y1 - 2015/08// PY - 2015 DA - August 2015 PB - Editorial Department of the Chinese Journal of Hygienic Insecticides & Equipment, 293 Zhongshan East Road Nanjing, Jiangsu Province, 210002 China VL - 21 IS - 4 SN - 1671-2781, 1671-2781 KW - Entomology Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources KW - military camp KW - vector KW - vector-borne diseases KW - risk evaluation KW - Symptoms KW - Hemorrhagic fever with renal syndrome KW - Culex pipiens pallens KW - Vector-borne diseases KW - Population density KW - Malaria KW - Hosts KW - Public health KW - Disease transmission KW - Fever KW - Insecticides KW - Aquatic insects KW - Cyclic AMP KW - Vectors KW - Aedes albopictus KW - Rattus norvegicus KW - Dominant species KW - Books KW - Anopheles sinensis KW - Rodentia KW - Hygiene KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - Q1 08485:Species interactions: pests and control KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1768577370?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chinese+Journal+of+Hygienic+Insecticides+%26+Equipment&rft.atitle=Investigation+and+analysis+of+important+medical+vectors+and+vector-borne+diseases+in+military+camps+in+Shandong&rft.au=Zhou%2C+Guang-zhi%3BWen%2C+Yu%3BLiu%2C+Yuan-dong%3BHuang%2C+Wei-chu%3BWang%2C+Zhi%3BHe%2C+Ying%3BYin%2C+Guang-qing&rft.aulast=Zhou&rft.aufirst=Guang-zhi&rft.date=2015-08-01&rft.volume=21&rft.issue=4&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Chinese+Journal+of+Hygienic+Insecticides+%26+Equipment&rft.issn=16712781&rft_id=info:doi/ LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Dominant species; Symptoms; Insecticides; Population density; Vectors; Hosts; Aquatic insects; Disease transmission; Public health; Fever; Hemorrhagic fever with renal syndrome; Books; Vector-borne diseases; Cyclic AMP; Malaria; Hygiene; Culex pipiens pallens; Anopheles sinensis; Rodentia; Aedes albopictus; Rattus norvegicus ER - TY - JOUR T1 - RE-TESTING AND SEROCONVERSION AMONG HIV TESTING AND COUNSELING CLIENTS IN LESOTHO AN - 1727696188; PQ0002160750 AB - HIV testing and counseling (HTC) is an essential component of comprehensive HIV programs. Retrospective HTC program data from 2006 to 2010 were examined to determine patterns of re-testing and seroconversion in Lesotho. Among 104,662 initially negative clients, 6,777 (6.5%) were re-testers. Predictors of re-testing included being male, age [> or =] 25 years, divorced/separated, having more than a high school education, being tested as a couple, testing in the year 2006, testing in the capital city, and awareness of partner's recent testing behavior. Among re-testers who seroconverted (N = 259), predictors included being female and having less than a high school education. There is a critical need for more effectively targeting HIV re-testing messages to align with WHO (2010) guidelines and identify persons at highest risk for HIV, to increase timely diagnoses and link persons to appropriate HIV prevention, care, and treatment services. JF - AIDS Education and Prevention AU - Grabbe, Kristina L AU - Courtenay-Quirk, Cari AU - Baughman, Andrew L AU - Djomand, Gaston AU - Pedersen, Brian AU - Lerotholi, Mankhala AU - Nkonyana, John AU - Ramphalla-Phatela, Puleng AU - Marum, Elizabeth AD - Division of Global HIV/AIDS, Centers for Disease Control and Prevention, Atlanta, Georgia, ccourtenayquirk@cdc.gov Y1 - 2015/08// PY - 2015 DA - August 2015 SP - 350 EP - 361 PB - Guilford Publications, Inc., 72 Spring Street, 4th Floor New York NY 10012 United States VL - 27 IS - 4 SN - 0899-9546, 0899-9546 KW - Health & Safety Science Abstracts; Risk Abstracts; Virology & AIDS Abstracts KW - Acquired immune deficiency syndrome KW - Age KW - Data processing KW - Guidelines KW - Lesotho KW - Education KW - Prevention KW - Behavior KW - Human immunodeficiency virus KW - Risk factors KW - Seroconversion KW - Urban areas KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727696188?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+Education+and+Prevention&rft.atitle=RE-TESTING+AND+SEROCONVERSION+AMONG+HIV+TESTING+AND+COUNSELING+CLIENTS+IN+LESOTHO&rft.au=Grabbe%2C+Kristina+L%3BCourtenay-Quirk%2C+Cari%3BBaughman%2C+Andrew+L%3BDjomand%2C+Gaston%3BPedersen%2C+Brian%3BLerotholi%2C+Mankhala%3BNkonyana%2C+John%3BRamphalla-Phatela%2C+Puleng%3BMarum%2C+Elizabeth&rft.aulast=Grabbe&rft.aufirst=Kristina&rft.date=2015-08-01&rft.volume=27&rft.issue=4&rft.spage=350&rft.isbn=&rft.btitle=&rft.title=AIDS+Education+and+Prevention&rft.issn=08999546&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-02-04 N1 - SubjectsTermNotLitGenreText - Age; Data processing; Risk factors; Seroconversion; Acquired immune deficiency syndrome; Prevention; Education; Behavior; Human immunodeficiency virus; Guidelines; Urban areas; Lesotho ER - TY - JOUR T1 - Population Size Estimates for Men who Have Sex with Men and Persons who Inject Drugs AN - 1712771368; PQ0001920715 AB - Understanding geographic variation in the numbers of men who have sex with men (MSM) and persons who inject drugs (PWID) is critical to targeting and scaling up HIV prevention programs, but population size estimates are not available at generalizable sub-national levels. We analyzed 1999-2010 National Health and Nutrition Examination Survey data on persons aged 18-59 years. We estimated weighted prevalence of recent (past 12 month) male-male sex and injection drug use by urbanicity (the degree to which a geographic area is urban) and US census region and calculated population sizes. Large metro areas (population greater than or equal to 1,000,000) had higher prevalence of male-male sex (central areas, 4.4 % of men; fringe areas, 2.5 %) compared with medium/small metro areas (1.4 %) and nonmetro areas (1.1 %). Injection drug use did not vary by urbanicity and neither varied by census region. Three-quarters of MSM, but only half of PWID, resided in large metro areas. Two-thirds of MSM and two-thirds of PWID resided in the South and West. Efforts to reach MSM would benefit from being focused in large metro areas, while efforts to reach PWID should be delivered more broadly. These data allow for more effective allocation of funds for prevention programs. JF - Journal of Urban Health AU - Oster, Alexandra M AU - Sternberg, Maya AU - Lansky, Amy AU - Broz, Dita AU - Wejnert, Cyprian AU - Paz-Bailey, Gabriela AD - Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP), Centers for Disease Control and Prevention, Atlanta, GA, USA, aoster@cdc.gov Y1 - 2015/08// PY - 2015 DA - Aug 2015 SP - 733 EP - 743 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 92 IS - 4 SN - 1099-3460, 1099-3460 KW - Health & Safety Science Abstracts KW - Prevention KW - Funds KW - Human immunodeficiency virus KW - Census KW - Homosexuality KW - Drug abuse KW - Drugs KW - Nutrition KW - Scaling KW - Population number KW - Urban areas KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1712771368?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Urban+Health&rft.atitle=Population+Size+Estimates+for+Men+who+Have+Sex+with+Men+and+Persons+who+Inject+Drugs&rft.au=Oster%2C+Alexandra+M%3BSternberg%2C+Maya%3BLansky%2C+Amy%3BBroz%2C+Dita%3BWejnert%2C+Cyprian%3BPaz-Bailey%2C+Gabriela&rft.aulast=Oster&rft.aufirst=Alexandra&rft.date=2015-08-01&rft.volume=92&rft.issue=4&rft.spage=733&rft.isbn=&rft.btitle=&rft.title=Journal+of+Urban+Health&rft.issn=10993460&rft_id=info:doi/10.1007%2Fs11524-015-9970-3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-09-01 N1 - Number of references - 15 N1 - Last updated - 2015-10-28 N1 - SubjectsTermNotLitGenreText - Funds; Prevention; Human immunodeficiency virus; Census; Homosexuality; Drug abuse; Scaling; Nutrition; Drugs; Urban areas; Population number DO - http://dx.doi.org/10.1007/s11524-015-9970-3 ER - TY - JOUR T1 - Trends in use of genotypic resistance testing and frequency of major drug resistance among antiretroviral-naive persons in the HIV Outpatient Study, 1999-2011 AN - 1712563949; PQ0001944576 AB - Background Monitoring antiretroviral drug resistance can inform treatment recommendations; however, there are few such data from US patients before they initiate ART. Methods We analysed data from HIV Outpatient Study (HOPS) participants from nine US HIV clinics who were diagnosed with HIV infection during 1999-2011. Using the IAS-USA December 2010 guidelines, we assessed the frequency of major drug resistance mutations (mDRMs) related to antiretroviral agents in viral isolates from patients who underwent commercial genotypic testing (GT) for resistance before initiating ART. We employed general linear regression models to assess factors associated with having undergone GT, and then factors associated with having mDRM. Results Among 1531 eligible patients, 758 (49.5%) underwent GT before first ART, increasing from 15.5% in 1999-2002 to 75.9% in 2009-11 (P5.0 log sub(10) copies/mL and those with a first HOPS visit in 2006 or later were significantly (P<0.05) more likely to have undergone GT. Of the 758 patients, 114 (15.0%) had mDRMs; mutations relating to NRTIs, NNRTIs and PIs were present in 8.0%, 7.1% and 2.6%, respectively. There was no temporal change in the frequency of mDRM, and mDRMs were associated with an HIV RNA level <4.0 log sub(10) copies/mL. Conclusions During 1999-2011, GT use among antiretroviral-naive patients became more common, but a quarter of patients in recent years remained untested. The frequency of mDRMs remained stable over time at about 15%. JF - Journal of Antimicrobial Chemotherapy AU - Buchacz, Kate AU - Young, Benjamin AU - Palella, Frank J AU - Armon, Carl AU - Brooks, John T Y1 - 2015/08// PY - 2015 DA - Aug 2015 SP - 2337 EP - 2346 PB - Oxford University Press, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 70 IS - 8 SN - 0305-7453, 0305-7453 KW - Virology & AIDS Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - HIV infection KW - genotype KW - mutation KW - epidemiology KW - primary KW - transmitted KW - Data processing KW - Drug resistance KW - antiretroviral therapy KW - Infection KW - hops KW - CD4 antigen KW - RNA KW - Antiviral agents KW - Human immunodeficiency virus KW - antiretroviral agents KW - Regression analysis KW - Lymphocytes T KW - Mutation KW - A 01340:Antibiotics & Antimicrobials KW - V 22360:AIDS and HIV UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1712563949?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Antimicrobial+Chemotherapy&rft.atitle=Trends+in+use+of+genotypic+resistance+testing+and+frequency+of+major+drug+resistance+among+antiretroviral-naive+persons+in+the+HIV+Outpatient+Study%2C+1999-2011&rft.au=Buchacz%2C+Kate%3BYoung%2C+Benjamin%3BPalella%2C+Frank+J%3BArmon%2C+Carl%3BBrooks%2C+John+T&rft.aulast=Buchacz&rft.aufirst=Kate&rft.date=2015-08-01&rft.volume=70&rft.issue=8&rft.spage=2337&rft.isbn=&rft.btitle=&rft.title=Journal+of+Antimicrobial+Chemotherapy&rft.issn=03057453&rft_id=info:doi/10.1093%2Fjac%2Fdkv120 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-09-01 N1 - Last updated - 2015-11-16 N1 - SubjectsTermNotLitGenreText - CD4 antigen; Data processing; Antiviral agents; RNA; Drug resistance; antiretroviral agents; antiretroviral therapy; Lymphocytes T; Regression analysis; Infection; Mutation; hops; Human immunodeficiency virus DO - http://dx.doi.org/10.1093/jac/dkv120 ER - TY - JOUR T1 - Maternal exposures in the National Birth Defects Prevention Study: Time trends of selected exposures AN - 1709189610; PQ0001901227 AB - Background Our objective was to describe time trends in selected pregnancy exposures in the National Birth Defects Prevention Study (NBDPS). Methods We analyzed data from the NBDPS, a multi-site case-control study of major birth defects, for mothers of live-born infants without birth defects (controls), with an expected date of delivery (EDD) from 1998 to 2011. Mothers from the 10 participating centers across the United States were interviewed by phone between 6 weeks and 2 years after the EDD. We focused on maternal race/ethnicity and five maternal risk factors: obesity, use of folic acid-containing multivitamins, opioid analgesics, selective serotonin reuptake inhibitors, and loratadine because of their prevalence of use and some reports of associations with major birth defects. Prevalence time trends were examined using the Kendall's tau sub( beta ) test statistic. Results The exposure trend analysis included 11,724 control mothers with EDDs from 1998 to 2011. We observed a significant increase in obesity prevalence among control mothers, as well as use of selective serotonin reuptake inhibitors and loratadine. We also observed an increase in periconceptional use of folic acid-containing multivitamins. Some of the time trends varied by race/ethnicity. No remarkable trend in the overall use of opioid analgesics was observed. The racial/ethnic distribution of mothers changed slightly during the study period. Conclusion Long-term, population-based case-control studies continue to be an effective way to assess exposure-birth defects associations and provide guidance to health care providers. However, investigators examining rare outcomes covering many years of data collection need to be cognizant of time trends in exposures. Birth Defects Research (Part A) 103:703-712, 2015. JF - Birth Defects Research Part A: Clinical and Molecular Teratology AU - Dawson, April L AU - Razzaghi, Hilda AU - Arth, Annelise AU - Canfield, Mark A AU - Parker, Samantha E AU - Reefhuis, Jennita AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia. Y1 - 2015/08// PY - 2015 DA - Aug 2015 SP - 703 EP - 712 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 103 IS - 8 SN - 1542-0752, 1542-0752 KW - Toxicology Abstracts KW - Obesity KW - Data processing KW - Serotonin uptake inhibitors KW - Data collections KW - Pregnancy KW - Risk factors KW - Congenital defects KW - Opioids KW - Analgesics KW - Ethnic groups KW - Races KW - Infants KW - X 24380:Social Poisons & Drug Abuse UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1709189610?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Birth+Defects+Research+Part+A%3A+Clinical+and+Molecular+Teratology&rft.atitle=Maternal+exposures+in+the+National+Birth+Defects+Prevention+Study%3A+Time+trends+of+selected+exposures&rft.au=Dawson%2C+April+L%3BRazzaghi%2C+Hilda%3BArth%2C+Annelise%3BCanfield%2C+Mark+A%3BParker%2C+Samantha+E%3BReefhuis%2C+Jennita&rft.aulast=Dawson&rft.aufirst=April&rft.date=2015-08-01&rft.volume=103&rft.issue=8&rft.spage=703&rft.isbn=&rft.btitle=&rft.title=Birth+Defects+Research+Part+A%3A+Clinical+and+Molecular+Teratology&rft.issn=15420752&rft_id=info:doi/10.1002%2Fbdra.23377 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-09-01 N1 - Last updated - 2015-11-16 N1 - SubjectsTermNotLitGenreText - Obesity; Data processing; Risk factors; Serotonin uptake inhibitors; Congenital defects; Opioids; Data collections; Analgesics; Races; Ethnic groups; Pregnancy; Infants DO - http://dx.doi.org/10.1002/bdra.23377 ER - TY - JOUR T1 - Injury Prevention Practices as Depicted in G- and PG-Rated Movies, 2008-2012 AN - 1709179071; PQ0001870527 AB - Unintentional injuries are the leading cause of death among children in the United States. The use of recommended safety practices can reduce injuries. Children often learn behaviors from media exposure. Children's movies released in 1995-2007 infrequently depicted appropriate injury prevention practices. The aim of this study was to determine if injury prevention practices in children's movies have improved. The top grossing 25 G- and PG-rated movies in the United States per year for 2008-2012 were eligible for inclusion in the study. Movies or scenes were excluded if they were animated, not set in the present day, fantasy, documentary, or not in English. Injury prevention practices involving riding in a motor vehicle, walking, boating, bicycling, and four other activities were recorded for characters with speaking roles. Fifty-six (45 %) of the 125 movies met the inclusion criteria. A total of 603 person-scenes were examined involving 175 (29 %) children and 428 (71 %) adults. Thirty-eight person-scenes involved crashes or falls, resulting in four injuries and no deaths. Overall, 59 % (353/603) of person-scenes showed appropriate injury prevention practices. This included 313 (70 %) of 445 motor-vehicle passengers who were belted; 15 (30 %) of 50 pedestrians who used a crosswalk, 2 (7 %) of 30 boaters who wore personal flotation devices, and 8 (29 %) of 28 bicyclists who wore helmets. In comparison with previous studies, there were significant increases in usage of seat belts, crosswalks, personal flotation devices, and bicycle helmets. However, 41 % of person-scenes still showed unsafe practices and the consequences of those behaviors were infrequently depicted. JF - Journal of Community Health AU - Pelletier, Andrew R AU - Tongren, JEric AU - Gilchrist, Julie AD - Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA, arp1@cdc.gov Y1 - 2015/08// PY - 2015 DA - Aug 2015 SP - 613 EP - 618 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 40 IS - 4 SN - 0094-5145, 0094-5145 KW - Health & Safety Science Abstracts KW - Mortality KW - Seat belts KW - Injuries KW - Helmets KW - Pedestrians KW - Motor vehicles KW - Safety KW - Children KW - Protective equipment KW - USA KW - Accidents KW - Prevention KW - Bicycles KW - Behavior KW - Flotation KW - H 2000:Transportation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1709179071?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Community+Health&rft.atitle=Injury+Prevention+Practices+as+Depicted+in+G-+and+PG-Rated+Movies%2C+2008-2012&rft.au=Pelletier%2C+Andrew+R%3BTongren%2C+JEric%3BGilchrist%2C+Julie&rft.aulast=Pelletier&rft.aufirst=Andrew&rft.date=2015-08-01&rft.volume=40&rft.issue=4&rft.spage=613&rft.isbn=&rft.btitle=&rft.title=Journal+of+Community+Health&rft.issn=00945145&rft_id=info:doi/10.1007%2Fs10900-014-9974-z LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-09-01 N1 - Number of references - 31 N1 - Last updated - 2015-09-17 N1 - SubjectsTermNotLitGenreText - Mortality; Seat belts; Injuries; Helmets; Motor vehicles; Pedestrians; Safety; Children; Protective equipment; Prevention; Accidents; Bicycles; Behavior; Flotation; USA DO - http://dx.doi.org/10.1007/s10900-014-9974-z ER - TY - JOUR T1 - Next steps for birth defects research and prevention: The birth defects study to evaluate pregnancy exposures (BD-STEPS) AN - 1709176513; PQ0001901226 AB - Background The Birth Defects Study To Evaluate Pregnancy exposureS (BD-STEPS) is a population-based, multi-Center case-control study of modifiable risk factors for selected birth defects in the United States. BD-STEPS is the second major research effort of the Centers for Birth Defects Research and Prevention, which extends and expands the initial research effort, the National Birth Defects Prevention Study (NBDPS). Methods BD-STEPS focuses on 17 categories of structural birth defects selected based on severity, prevalence, consistent ascertainment, and previous findings that warrant additional research. Cases are identified through existing birth defects surveillance programs; controls are from vital records or birth hospital logs from the same catchment area. BD-STEPS uses a standardized computer-assisted telephone interview to collect information from case and control mothers on topics including demographics, health conditions, and medication use. Following the maternal interview, selected Centers request permission to sample residual newborn screening blood spots from state repositories for genetic analyses. New components planned for BD-STEPS include linkages with external datasets and use of online questionnaires to collect in-depth information on selected exposures. Results BD-STEPS extends NBDPS by continuing to collect data on many exposures that were assessed in NBDPS, allowing data from both studies to be combined and providing an unprecedented sample size to analyze rare exposures. BD-STEPS expands upon NBDPS by collecting more detailed information on existing exposures as well as new exposures. Conclusion The goal of BD-STEPS is to provide women and healthcare providers with information they need to make decisions to promote the healthiest pregnancy possible. Birth Defects Research (Part A) 103:733-740, 2015. JF - Birth Defects Research Part A: Clinical and Molecular Teratology AU - Tinker, Sarah C AU - Carmichael, Suzan L AU - Anderka, Marlene AU - Browne, Marilyn L AU - Caspers Conway, Kristin M AU - Meyer, Robert E AU - Nembhard, Wendy N AU - Olney, Richard S AU - Reefhuis, Jennita AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia. Y1 - 2015/08// PY - 2015 DA - Aug 2015 SP - 733 EP - 740 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 103 IS - 8 SN - 1542-0752, 1542-0752 KW - Toxicology Abstracts KW - Inventories KW - Data processing KW - Genetic analysis KW - Pregnancy KW - Birth KW - Demography KW - Decision making KW - Blood KW - Catchment areas KW - Risk factors KW - Congenital defects KW - Neonates KW - Internet KW - Hospitals KW - X 24500:Reviews, Legislation, Book & Conference Notices UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1709176513?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Birth+Defects+Research+Part+A%3A+Clinical+and+Molecular+Teratology&rft.atitle=Next+steps+for+birth+defects+research+and+prevention%3A+The+birth+defects+study+to+evaluate+pregnancy+exposures+%28BD-STEPS%29&rft.au=Tinker%2C+Sarah+C%3BCarmichael%2C+Suzan+L%3BAnderka%2C+Marlene%3BBrowne%2C+Marilyn+L%3BCaspers+Conway%2C+Kristin+M%3BMeyer%2C+Robert+E%3BNembhard%2C+Wendy+N%3BOlney%2C+Richard+S%3BReefhuis%2C+Jennita&rft.aulast=Tinker&rft.aufirst=Sarah&rft.date=2015-08-01&rft.volume=103&rft.issue=8&rft.spage=733&rft.isbn=&rft.btitle=&rft.title=Birth+Defects+Research+Part+A%3A+Clinical+and+Molecular+Teratology&rft.issn=15420752&rft_id=info:doi/10.1002%2Fbdra.23373 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-09-01 N1 - Last updated - 2015-11-16 N1 - SubjectsTermNotLitGenreText - Inventories; Data processing; Genetic analysis; Pregnancy; Demography; Birth; Blood; Decision making; Catchment areas; Risk factors; Congenital defects; Neonates; Internet; Hospitals DO - http://dx.doi.org/10.1002/bdra.23373 ER - TY - JOUR T1 - Nicotine and the Developing Human: A Neglected Element in the Electronic Cigarette Debate. AN - 1697751740; 25794473 AB - The elimination of cigarettes and other combusted tobacco products in the U.S. would prevent tens of millions of tobacco-related deaths. It has been suggested that the introduction of less harmful nicotine delivery devices, such as electronic cigarettes or other electronic nicotine delivery systems, will accelerate progress toward ending combustible cigarette use. However, careful consideration of the potential adverse health effects from nicotine itself is often absent from public health debates. Human and animal data support that nicotine exposure during periods of developmental vulnerability (fetal through adolescent stages) has multiple adverse health consequences, including impaired fetal brain and lung development, and altered development of cerebral cortex and hippocampus in adolescents. Measures to protect the health of pregnant women and children are needed and could include (1) strong prohibitions on marketing that increase youth uptake; (2) youth access laws similar to those in effect for other tobacco products; (3) appropriate health warnings for vulnerable populations; (4) packaging to prevent accidental poisonings; (5) protection of non-users from exposure to secondhand electronic cigarette aerosol; (6) pricing that helps minimize youth initiation and use; (7) regulations to reduce product addiction potential and appeal for youth; and (8) the age of legal sale. Published by Elsevier Inc. JF - American journal of preventive medicine AU - England, Lucinda J AU - Bunnell, Rebecca E AU - Pechacek, Terry F AU - Tong, Van T AU - McAfee, Tim A AD - Office on Smoking and Health. Electronic address: lbe9@cdc.gov. ; Office on Smoking and Health. ; Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, CDC, Atlanta, Georgia. Y1 - 2015/08// PY - 2015 DA - August 2015 SP - 286 EP - 293 VL - 49 IS - 2 KW - Nicotine KW - 6M3C89ZY6R KW - Index Medicus KW - United States KW - Animals KW - Public Health KW - Commerce -- legislation & jurisprudence KW - Tobacco Products -- supply & distribution KW - Humans KW - Child KW - Tobacco Products -- adverse effects KW - Adolescent KW - Female KW - Pregnancy KW - Nicotine -- adverse effects KW - Electronic Cigarettes -- adverse effects KW - Smoking -- adverse effects KW - Smoking -- prevention & control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1697751740?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+journal+of+preventive+medicine&rft.atitle=Nicotine+and+the+Developing+Human%3A+A+Neglected+Element+in+the+Electronic+Cigarette+Debate.&rft.au=England%2C+Lucinda+J%3BBunnell%2C+Rebecca+E%3BPechacek%2C+Terry+F%3BTong%2C+Van+T%3BMcAfee%2C+Tim+A&rft.aulast=England&rft.aufirst=Lucinda&rft.date=2015-08-01&rft.volume=49&rft.issue=2&rft.spage=286&rft.isbn=&rft.btitle=&rft.title=American+journal+of+preventive+medicine&rft.issn=1873-2607&rft_id=info:doi/10.1016%2Fj.amepre.2015.01.015 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2016-04-18 N1 - Date created - 2015-07-20 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Cited By: Environ Health Perspect. 2005 Jan;113(1):98-103 [15626655] Toxicology. 2005 May 5;209(3):245-61 [15795061] Chest. 2005 Apr;127(4):1232-41 [15821200] Epidemiology. 2006 Jan;17(1):47-51 [16357594] Paediatr Perinat Epidemiol. 2006 Mar;20(2):90-9 [16466427] AAPS J. 2005;7(4):E885-94 [16594641] J Health Psychol. 2007 Mar;12(2):215-24 [17284486] Psychopharmacology (Berl). 2007 Mar;191(1):159-69 [16937098] Obstet Gynecol. 2011 Sep;118(3):746-50 [21860316] Neurobiol Learn Mem. 2014 Jan;107:108-32 [23973448] JAMA. 2014 Jan 8;311(2):135-6 [24399548] Behav Neurosci. 2007 Dec;121(6):1342-52 [18085887] Environ Health Perspect. 2011 Sep;119(9):1218-26 [21628107] Tob Control. 2011 Nov;20(6):425-6 [21659450] Pediatrics. 2011 Sep;128(3):503-9 [21873701] MMWR Morb Mortal Wkly Rep. 2014 Sep 5;63(35):765-9 [25188494] J Adolesc Health. 2014 Nov;55(5):713-5 [25344033] MMWR Morb Mortal Wkly Rep. 2014 Nov 14;63(45):1021-6 [25393220] Environ Res. 2014 Nov;135:76-80 [25262078] Nicotine Tob Res. 2015 Feb;17(2):228-35 [25143298] Nicotine Tob Res. 2015 Feb;17(2):256-8 [25173774] Nicotine Tob Res. 2015 Feb;17(2):219-27 [25239961] Neurotoxicol Teratol. 2008 Jan-Feb;30(1):1-19 [18380035] Birth Defects Res C Embryo Today. 2008 Mar;84(1):30-44 [18383130] Br J Pharmacol. 2008 Aug;154(8):1558-71 [18500366] Eur J Epidemiol. 2012 Apr;27(4):297-304 [22430122] Cold Spring Harb Perspect Med. 2012 Dec;2(12):a012120 [22983224] Inhal Toxicol. 2013 Feb;25(2):91-101 [23363041] BMC Med. 2012;10:129 [23106849] BMC Med. 2013;11:27 [23379695] Public Health Rep. 2013 May-Jun;128(3):179-88 [23633733] Prev Chronic Dis. 2013;10:E79 [23680508] MMWR Morb Mortal Wkly Rep. 2013 Sep 6;62(35):729-30 [24005229] Ann Epidemiol. 2013 Oct;23(10):652-61 [23969303] Harm Reduct J. 2013;10:19 [24090432] PLoS One. 2013;8(10):e79332 [24250756] Addict Behav. 2014 Mar;39(3):507-11 [24290207] Am J Public Health. 2014 Feb;104 Suppl 1:S43-8 [24354819] MMWR Morb Mortal Wkly Rep. 2014 Apr 4;63(13):292-3 [24699766] Circulation. 2014 May 13;129(19):1972-86 [24821826] Int J Hyg Environ Health. 2014 Jul;217(6):628-37 [24373737] Pediatrics. 2014 Jul;134(1):e29-36 [24918224] N Engl J Med. 2014 Sep 4;371(10):932-43 [25184865] Am J Prev Med. 2008 Oct;35(4):327-33 [18779027] Neuropharmacology. 2009;56 Suppl 1:263-78 [18723034] Physiol Rev. 2009 Jan;89(1):73-120 [19126755] Neurosci Biobehav Rev. 2009 Mar;33(3):367-82 [19028521] Nat Rev Neurosci. 2009 Apr;10(4):303-12 [19277053] Pharmacol Ther. 2009 May;122(2):125-39 [19268688] Biochem Pharmacol. 2009 Oct 1;78(7):668-76 [19426718] Am J Prev Med. 2010 Jul;39(1):45-52 [20547278] Epidemiology. 2010 Nov;21(6):772-8 [20805750] Neuropsychopharmacology. 2011 Jan;36(1):356-7 [21116249] Int J Environ Res Public Health. 2011 Mar;8(3):875-98 [21556184] Brain Res. 2000 Oct 13;880(1-2):167-72 [11033001] Brain Res. 2001 Apr 27;899(1-2):94-100 [11311869] J Am Acad Child Adolesc Psychiatry. 2001 Sep;40(9):1012-20 [11556624] Am J Respir Crit Care Med. 2001 Sep 15;164(6):989-94 [11587984] Am J Respir Cell Mol Biol. 2002 Jan;26(1):31-41 [11751201] Respirology. 2003 Sep;8(3):266-85 [14528876] Behav Brain Res. 2004 Apr 2;150(1-2):159-70 [15033289] BMJ. 2004 Jun 26;328(7455):1538 [15198947] Ann N Y Acad Sci. 2004 Jun;1021:77-85 [15251877] Int J Dev Neurosci. 2004 Aug-Oct;22(5-6):329-37 [15380832] Brain Res Bull. 1987 May;18(5):601-11 [3607529] Am Rev Respir Dis. 1992 May;145(5):1129-35 [1586058] Am J Respir Crit Care Med. 1995 Sep;152(3):977-83 [7663813] Brain Res Dev Brain Res. 1996 Dec 23;97(2):207-15 [8997505] Eur Respir J. 1997 Aug;10(8):1774-9 [9272918] J Pharmacol Exp Ther. 1998 Jun;285(3):931-45 [9618392] Brain Res Dev Brain Res. 1998 Jun 15;108(1-2):147-60 [9693793] J Clin Invest. 1999 Mar;103(5):637-47 [10074480] Biol Psychiatry. 2005 Jan 1;57(1):56-66 [15607301] Neuropsychopharmacology. 2005 Jan;30(1):129-44 [15316571] Comment In: Am J Prev Med. 2016 Jan;50(1):e27 [26706256] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1016/j.amepre.2015.01.015 ER - TY - JOUR T1 - Trends in Disease and Complications of Hepatitis A Virus Infection in the United States, 1999-2011: A New Concern for Adults AN - 1768577893; PQ0002673955 AB - Background. In recent years, few US adults have had exposure and resultant immunity to hepatitis A virus (HAV). Further, persons with liver disease have an increased risk of adverse consequences if they are infected with HAV. Methods. This study used 1999-2011 National Notifiable Diseases Surveillance System and Multiple Cause of Death data to assess trends in the incidence of HAV infection, HAV-related hospitalization, and HAV-related mortality. Results. During 1999-2011, the incidence of HAV infection declined from 6.0 cases/100 000 to 0.4 cases/100 000. Similar declines were seen by sex and age, but persons aged > or =80 years had the highest incidence of HAV infection in 2011 (0.8 cases/100 000). HAV-related hospitalizations increased from 7.3% in 1999 to 24.5% in 2011. The mean age of hospitalized cases increased from 36.0 years in 1999 to 45.1 years in 2011. While HAV-related mortality declined, the mean age at death among decedents with HAV infection increased from 48.0 years in 1999 to 76.2 years in 2011. The median age range of decedents who had HAV infection and a liver-related condition was 51.0 to 68.0 years. Conclusions. Although vaccine-preventable, HAV-related hospitalizations increased greatly, mostly among adults, and liver-related conditions were frequently reported among HAV-infected individuals who died. Public health efforts should focus on the need to assess protection from hepatitis A among adults, including those with liver disease. JF - Journal of Infectious Diseases AU - Ly, Kathleen N AU - Klevens, R Monina AD - Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, Georgia, kathleenly@cdc.gov Y1 - 2015/07/15/ PY - 2015 DA - 2015 Jul 15 SP - 176 EP - 182 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 212 IS - 2 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - hepatitis A virus KW - hepatitis A hospitalizations KW - hepatitis A mortality KW - hepatitis A complications KW - hepatitis A trends KW - Risk assessment KW - Mortality KW - Age KW - Liver diseases KW - Data processing KW - Complications KW - Hepatitis A virus KW - Immunity KW - Infection KW - Public health KW - USA KW - Infectious diseases KW - Liver KW - Hepatitis A KW - Vaccines KW - Hospitals KW - Sex KW - H 4000:Food and Drugs KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1768577893?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Trends+in+Disease+and+Complications+of+Hepatitis+A+Virus+Infection+in+the+United+States%2C+1999-2011%3A+A+New+Concern+for+Adults&rft.au=Ly%2C+Kathleen+N%3BKlevens%2C+R+Monina&rft.aulast=Ly&rft.aufirst=Kathleen&rft.date=2015-07-15&rft.volume=212&rft.issue=2&rft.spage=176&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiu834 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Mortality; Age; Data processing; Liver diseases; Hepatitis A; Immunity; Infection; Sex; Public health; Risk assessment; Infectious diseases; Complications; Liver; Vaccines; Hospitals; Hepatitis A virus; USA DO - http://dx.doi.org/10.1093/infdis/jiu834 ER - TY - JOUR T1 - Validation of Multilevel Regression and Poststratification Methodology for Small Area Estimation of Health Indicators From the Behavioral Risk Factor Surveillance System AN - 1732835040; PQ0001938033 AB - Small area estimation is a statistical technique used to produce reliable estimates for smaller geographic areas than those for which the original surveys were designed. Such small area estimates (SAEs) often lack rigorous external validation. In this study, we validated our multilevel regression and poststratification SAEs from 2011 Behavioral Risk Factor Surveillance System data using direct estimates from 2011 Missouri County-Level Study and American Community Survey data at both the state and county levels. Coefficients for correlation between model-based SAEs and Missouri County-Level Study direct estimates for 115 counties in Missouri were all significantly positive (0.28 for obesity and no health-care coverage, 0.40 for current smoking, 0.51 for diabetes, and 0.69 for chronic obstructive pulmonary disease). Coefficients for correlation between model-based SAEs and American Community Survey direct estimates of no health-care coverage were 0.85 at the county level (811 counties) and 0.95 at the state level. Unweighted and weighted model-based SAEs were compared with direct estimates; unweighted models performed better. External validation results suggest that multilevel regression and poststratification model-based SAEs using single-year Behavioral Risk Factor Surveillance System data are valid and could be used to characterize geographic variations in health indictors at local levels (such as counties) when high-quality local survey data are not available. JF - American Journal of Epidemiology AU - Zhang, Xingyou AU - Holt, James B AU - Yun, Shumei AU - Lu, Hua AU - Greenlund, Kurt J AU - Croft, Janet B AD - Correspondence to Dr. Xingyou Zhang, Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway, Mailstop F78, Atlanta, GA 30341, gyx8@cdc.gov PY - 2015 SP - 127 EP - 137 PB - Oxford University Press, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 182 IS - 2 SN - 0002-9262, 0002-9262 KW - Risk Abstracts KW - American Community Survey KW - Behavioral Risk Factor Surveillance System KW - external validation KW - Missouri County-Level Study KW - multilevel regression and poststratification KW - small area estimation KW - Diabetes mellitus KW - Obesity KW - Smoking KW - Risk factors KW - USA, Missouri KW - Chronic obstructive pulmonary disease KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1732835040?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Epidemiology&rft.atitle=Validation+of+Multilevel+Regression+and+Poststratification+Methodology+for+Small+Area+Estimation+of+Health+Indicators+From+the+Behavioral+Risk+Factor+Surveillance+System&rft.au=Zhang%2C+Xingyou%3BHolt%2C+James+B%3BYun%2C+Shumei%3BLu%2C+Hua%3BGreenlund%2C+Kurt+J%3BCroft%2C+Janet+B&rft.aulast=Zhang&rft.aufirst=Xingyou&rft.date=2015-07-05&rft.volume=182&rft.issue=2&rft.spage=127&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Epidemiology&rft.issn=00029262&rft_id=info:doi/10.1093%2Faje%2Fkwv002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-11-01 N1 - Last updated - 2015-12-09 N1 - SubjectsTermNotLitGenreText - Diabetes mellitus; Smoking; Obesity; Risk factors; Chronic obstructive pulmonary disease; USA, Missouri DO - http://dx.doi.org/10.1093/aje/kwv002 ER - TY - JOUR T1 - Association between current asthma and secondhand smoke exposure in vehicles among adults living in four US states AN - 1808637198; PQ0003436060 AB - ObjectiveMany states have implemented laws prohibiting tobacco smoking in indoor public places. However, private settings remain a major source of secondhand smoke (SHS) exposure for many people. We assessed the association between current asthma and SHS exposure in vehicles among adult never-smokers in Indiana, Kentucky, Louisiana and Mississippi.MethodsData came from the 2011 Behavioral Risk Factor Surveillance System, a state-based telephone survey of US adults aged greater than or equal to 18years. Analyses were restricted to states (n=4) that administered an optional SHS module. Prevalence of self-reported asthma and past 7-day SHS exposure in vehicles was calculated by demographics, voluntary smoke-free vehicle rules and SHS exposure in homes, public places and workplaces. Logistic regression was used to assess the adjusted association between asthma and SHS exposure in vehicles.ResultsAmong 17863 never-smoking adults, 7.4% reported having current asthma, whereas 12.3% reported past 7-day SHS exposure in vehicles. Among adults with asthma, SHS exposure in vehicles was lower among those with voluntary smoke-free rules compared with those without voluntary smoke-free rules (9.5% vs 56.7%, p<0.0001). Following adjustment, adults exposed to SHS in a vehicle had a higher odds of having current asthma compared with unexposed adults (OR=2.01, 95% CI 1.18 to 3.40).ConclusionsNever-smoking adults recently exposed to SHS in a vehicle had higher odds of having current asthma compared with unexposed adults. Efforts are warranted to warn about the dangers of SHS and to encourage voluntary smoke-free rules in vehicles, especially among adults with asthma. JF - Tobacco Control AU - Nguyen, Kimberly H AU - King, Brian A AU - Dube, Shanta R AD - Office on Smoking and Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, , Atlanta, Georgia, USA Y1 - 2015/07/02/ PY - 2015 DA - 2015 Jul 02 SP - 376 EP - 381 PB - BMJ Publishing Group Ltd. VL - 24 IS - 4 SN - 0964-4563, 0964-4563 KW - Toxicology Abstracts KW - Surveillance and monitoring KW - Secondhand smoke KW - Public policy KW - Smoke KW - Demography KW - Tobacco smoking KW - Risk factors KW - Asthma KW - X 24380:Social Poisons & Drug Abuse UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808637198?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Tobacco+Control&rft.atitle=Association+between+current+asthma+and+secondhand+smoke+exposure+in+vehicles+among+adults+living+in+four+US+states&rft.au=Nguyen%2C+Kimberly+H%3BKing%2C+Brian+A%3BDube%2C+Shanta+R&rft.aulast=Nguyen&rft.aufirst=Kimberly&rft.date=2015-07-02&rft.volume=24&rft.issue=4&rft.spage=376&rft.isbn=&rft.btitle=&rft.title=Tobacco+Control&rft.issn=09644563&rft_id=info:doi/10.1136%2Ftobaccocontrol-2013-051526 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-08-17 N1 - SubjectsTermNotLitGenreText - Demography; Smoke; Tobacco smoking; Risk factors; Asthma DO - http://dx.doi.org/10.1136/tobaccocontrol-2013-051526 ER - TY - JOUR T1 - A Recently Discovered Pathogenic Paramyxovirus, Sosuga Virus, is Present in Rousettus aegyptiacus Fruit Bats at Multiple Locations in Uganda AN - 1837336402; PQ0003751839 AB - In August 2012, a wildlife biologist became ill immediately following a 6-wk field trip to collect bats and rodents in South Sudan and Uganda. After returning to the US, the biologist was admitted to the hospital with multiple symptoms including fever, malaise, headache, generalized myalgia and arthralgia, stiffness in the neck, and sore throat. Soon after admission, the patient developed a maculopapular rash and oropharynx ulcerations. The patient remained hospitalized for 14 d. Several suspect pathogens, including viral hemorrhagic fever viruses such as Ebola viruses and Marburg viruses, were ruled out through standard diagnostic testing. However, deep sequencing and metagenomic analyses identified a novel paramyxovirus, later named Sosuga virus, in the patient's blood. To determine the potential source, bat tissues collected during the 3-wk period just prior to the onset of symptoms were tested for Sosuga virus, and several Egyptian rousette bats (Rousettus aegyptiacus) were found to be positive. Further analysis of archived Egyptian rousette tissues collected at other localities in Uganda found additional Sosuga virus-positive bats, suggesting this species could be a potential natural reservoir for this novel paramyxovirus. JF - Journal of Wildlife Diseases AU - Amman, Brian R AU - Albarino, Cesar G AU - Bird, Brian H AU - Nyakarahuka, Luke AU - Sealy, Tara K AU - Balinandi, Stephen AU - Schuh, Amy J AU - Campbell, Shelly M AU - Stroher, Ute AU - Jones, Megan E B AD - Centers for Disease Control and Prevention, Viral Special Pathogens Branch, 1600 Clifton Rd. NE, Atlanta, Georgia 30333, USA Y1 - 2015/07// PY - 2015 DA - July 2015 SP - 774 EP - 779 PB - Allen Press, Inc., 810 East Tenth St. Lawrence KS 66044 United States VL - 51 IS - 3 SN - 0090-3558, 0090-3558 KW - Virology & AIDS Abstracts; Ecology Abstracts KW - Bats KW - paramyxovirus KW - Rousettus aegyptiacus KW - Sosuga virus KW - spillover KW - wildlife biologist KW - Fruits KW - Oropharynx KW - Ebolavirus KW - Wildlife KW - Paramyxovirus KW - Pharyngitis KW - Pathogens KW - Neck KW - Fever KW - Blood KW - Exanthema KW - Headache KW - Hemorrhagic fever KW - Marburgvirus KW - Arthralgia KW - Myalgia KW - Hospitals KW - D 04040:Ecosystem and Ecology Studies KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1837336402?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Wildlife+Diseases&rft.atitle=A+Recently+Discovered+Pathogenic+Paramyxovirus%2C+Sosuga+Virus%2C+is+Present+in+Rousettus+aegyptiacus+Fruit+Bats+at+Multiple+Locations+in+Uganda&rft.au=Amman%2C+Brian+R%3BAlbarino%2C+Cesar+G%3BBird%2C+Brian+H%3BNyakarahuka%2C+Luke%3BSealy%2C+Tara+K%3BBalinandi%2C+Stephen%3BSchuh%2C+Amy+J%3BCampbell%2C+Shelly+M%3BStroher%2C+Ute%3BJones%2C+Megan+E+B&rft.aulast=Amman&rft.aufirst=Brian&rft.date=2015-07-01&rft.volume=51&rft.issue=3&rft.spage=774&rft.isbn=&rft.btitle=&rft.title=Journal+of+Wildlife+Diseases&rft.issn=00903558&rft_id=info:doi/10.7589%2F2015-02-044 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-11-01 N1 - Last updated - 2016-11-09 N1 - SubjectsTermNotLitGenreText - Fruits; Oropharynx; Wildlife; Pathogens; Pharyngitis; Neck; Fever; Exanthema; Blood; Headache; Hemorrhagic fever; Myalgia; Arthralgia; Hospitals; Ebolavirus; Paramyxovirus; Marburgvirus DO - http://dx.doi.org/10.7589/2015-02-044 ER - TY - JOUR T1 - Collection and Utilization of Animal Carcasses Associated with zoonotic Disease in Tshuapa District, the Democratic Republic of the Congo, 2012 AN - 1837329272; PQ0003751831 AB - The collection and consumption of animal carcasses is a common activity in forested areas of the Congo River basin and creates sustainability, conservation, and health concerns. Residents of the Tshuapa District reported collecting the remains of 5,878 animals from >30 species when surveyed about their wildlife consumption habits. Carcasses were discovered in varying degrees of decomposition and were often consumed at home or sold in local markets. The most commonly collected animals were Cricetomys gambianus(Northern giant pouched rat), Cercopithecus ascanius(red-tailed monkey), and Heliosciurus rufobrachium(red-legged sun squirrel). Many of the species recorded may be hosts of zoonotic pathogens, creating concern for spillover events. JF - Journal of Wildlife Diseases AU - Monroe, Benjamin P AU - Doty, Jeffrey B AU - Moses, Cynthia AU - Ibata, Saturnin AU - Reynolds, Mary AU - Carroll, Darin AD - Poxvirus and Rabies Program, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Mailstop A-30, 1600 Clifton Road, Atlanta Georgia, USA, BMonroe@cdc.gov Y1 - 2015/07// PY - 2015 DA - July 2015 SP - 734 EP - 738 PB - Allen Press, Inc., 810 East Tenth St. Lawrence KS 66044 United States VL - 51 IS - 3 SN - 0090-3558, 0090-3558 KW - Ecology Abstracts KW - Bushmeat KW - carcass KW - Ebola KW - monkeypox KW - primate KW - rodent KW - spillover KW - Carcasses KW - Sun KW - Wildlife KW - Cercopithecus KW - Conservation KW - River basins KW - Pathogens KW - Decomposition KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1837329272?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Wildlife+Diseases&rft.atitle=Collection+and+Utilization+of+Animal+Carcasses+Associated+with+zoonotic+Disease+in+Tshuapa+District%2C+the+Democratic+Republic+of+the+Congo%2C+2012&rft.au=Monroe%2C+Benjamin+P%3BDoty%2C+Jeffrey+B%3BMoses%2C+Cynthia%3BIbata%2C+Saturnin%3BReynolds%2C+Mary%3BCarroll%2C+Darin&rft.aulast=Monroe&rft.aufirst=Benjamin&rft.date=2015-07-01&rft.volume=51&rft.issue=3&rft.spage=734&rft.isbn=&rft.btitle=&rft.title=Journal+of+Wildlife+Diseases&rft.issn=00903558&rft_id=info:doi/10.7589%2F2014-05-140 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-11-01 N1 - Last updated - 2016-11-09 N1 - SubjectsTermNotLitGenreText - Carcasses; Wildlife; Sun; Conservation; River basins; Pathogens; Decomposition; Cercopithecus DO - http://dx.doi.org/10.7589/2014-05-140 ER - TY - JOUR T1 - Body mass index, respiratory conditions, asthma, and chronic obstructive pulmonary disease AN - 1827917951; PQ0001902535 AB - Background This study aims to assess the relationship of body mass index (BMI) status with respiratory conditions, asthma, and chronic obstructive pulmonary disease (COPD) in a state population. Methods Self-reported data from 11,868 adults aged greater than or equal to 18 years in the 2012 South Carolina Behavioral Risk Factor Surveillance System telephone survey were analyzed using multivariable logistic regression that accounted for the complex sampling design and adjusted for sex, age, race/ethnicity, education, smoking status, physical inactivity, and cancer history. Results The distribution of BMI (kg/m2) was 1.5% for underweight (<18.5), 32.3% for normal weight (18.5-24.9), 34.6% for overweight (25.0-29.9), 26.5% for obese (30.0-39.9), and 5.1% for morbidly obese ( greater than or equal to 40.0). Among respondents, 10.0% had frequent productive cough, 4.3% had frequent shortness of breath (SOB), 7.3% strongly agreed that SOB affected physical activity, 8.4% had current asthma, and 7.4% had COPD. Adults at extremes of body weight were more likely to report having asthma or COPD, and to report respiratory conditions. Age-adjusted U-shaped relationships of BMI categories with current asthma and strongly agreeing that SOB affected physical activity, but not U-shaped relationship with COPD, persisted after controlling for the covariates (p < 0.001). Morbidly obese but not underweight or obese respondents were significantly more likely to have frequent productive cough and frequent SOB than normal weight adults after adjustment. Conclusion Our data confirm that both underweight and obesity are associated with current asthma and obesity with COPD. Increased emphasis on exercise and nutrition may improve respiratory conditions. JF - Respiratory Medicine AU - Liu, Yong AU - Pleasants, Roy A AU - Croft, Janet B AU - Lugogo, Njira AU - Ohar, Jill AU - Heidari, Khosrow AU - Strange, Charlie AU - Wheaton, Anne G AU - Mannino, David M AU - Kraft, Monica AD - Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Atlanta, GA, USA Y1 - 2015/07// PY - 2015 DA - July 2015 SP - 851 EP - 859 PB - Elsevier B.V., Radarweg 29 Amsterdam 1043 NX Netherlands VL - 109 IS - 7 SN - 0954-6111, 0954-6111 KW - Toxicology Abstracts KW - Body mass index KW - Chronic obstructive pulmonary disease KW - Asthma KW - Respiratory conditions KW - Population-based study KW - COPD chronic obstructive pulmonary disease KW - BRFSS Behavioral Risk Factor Surveillance System KW - SOB shortness of breath KW - BMI body mass index KW - Obesity KW - Data processing KW - Physical activity KW - Cough KW - Underweight KW - Nutrition KW - Cancer KW - Physical training KW - Smoking KW - Body weight KW - Risk factors KW - Sampling KW - Ethnic groups KW - X 24380:Social Poisons & Drug Abuse UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1827917951?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Respiratory+Medicine&rft.atitle=Body+mass+index%2C+respiratory+conditions%2C+asthma%2C+and+chronic+obstructive+pulmonary+disease&rft.au=Liu%2C+Yong%3BPleasants%2C+Roy+A%3BCroft%2C+Janet+B%3BLugogo%2C+Njira%3BOhar%2C+Jill%3BHeidari%2C+Khosrow%3BStrange%2C+Charlie%3BWheaton%2C+Anne+G%3BMannino%2C+David+M%3BKraft%2C+Monica&rft.aulast=Liu&rft.aufirst=Yong&rft.date=2015-07-01&rft.volume=109&rft.issue=7&rft.spage=851&rft.isbn=&rft.btitle=&rft.title=Respiratory+Medicine&rft.issn=09546111&rft_id=info:doi/10.1016%2Fj.rmed.2015.05.006 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-10-01 N1 - Number of references - 49 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Obesity; Data processing; Physical activity; Asthma; Cough; Underweight; Nutrition; Cancer; Physical training; Chronic obstructive pulmonary disease; Smoking; Body weight; Risk factors; Sampling; Body mass index; Ethnic groups DO - http://dx.doi.org/10.1016/j.rmed.2015.05.006 ER - TY - JOUR T1 - Rotavirus Group A Genotypes Detected Through Diarrheal Disease Surveillance in Haiti, 2012 AN - 1722168468; PQ0002060601 AB - Samples collected in 2012 through diarrheal disease surveillance in Haiti were tested for rotavirus by enzyme immunoassay and real time RT-PCR and positive samples were genotyped. The predominant genotypes were G1P[8] (29% prevalence) and G9P[8] (21%). The observed genotype prevalence was similar to that reported previously for other Caribbean countries. JF - American Journal of Tropical Medicine and Hygiene AU - Esona, Mathew D AU - Buteau, Josiane AU - Lucien, Mentor Ali Ber AU - Joseph, Gerard A AU - Leshem, Eyal AU - Boncy, Jacques AU - Katz, Mark A AU - Bowen, Michael D AU - Balajee, S Arunmozhi AD - Centers for Disease Control and Prevention, Atlanta, Georgia, mkb6@cdc.gov Y1 - 2015/07// PY - 2015 DA - July 2015 SP - 54 EP - 56 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 93 IS - 1 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Rotavirus KW - Diarrhea KW - Surveillance and enforcement KW - Genotypes KW - Enzyme immunoassay KW - Polymerase chain reaction KW - Disease detection KW - Hygiene KW - Immunoassays KW - ASW, Caribbean Sea, Greater Antilles, Haiti KW - K 03330:Biochemistry KW - Q1 08604:Stock assessment and management KW - Q5 08524:Public health, medicines, dangerous organisms KW - V 22310:Genetics, Taxonomy & Structure KW - J 02300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1722168468?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Rotavirus+Group+A+Genotypes+Detected+Through+Diarrheal+Disease+Surveillance+in+Haiti%2C+2012&rft.au=Esona%2C+Mathew+D%3BButeau%2C+Josiane%3BLucien%2C+Mentor+Ali+Ber%3BJoseph%2C+Gerard+A%3BLeshem%2C+Eyal%3BBoncy%2C+Jacques%3BKatz%2C+Mark+A%3BBowen%2C+Michael+D%3BBalajee%2C+S+Arunmozhi&rft.aulast=Esona&rft.aufirst=Mathew&rft.date=2015-07-01&rft.volume=93&rft.issue=1&rft.spage=54&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0403 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Surveillance and enforcement; Polymerase chain reaction; Disease detection; Genotypes; Hygiene; Immunoassays; Diarrhea; Enzyme immunoassay; Rotavirus; ASW, Caribbean Sea, Greater Antilles, Haiti DO - http://dx.doi.org/10.4269/ajtmh.14-0403 ER - TY - JOUR T1 - Social support and condom use among female sex workers in China AN - 1704341620; 4694346 AB - While the relationship between social support and psychological well-being has been well established, limited studies have explored how social support might affect condom use among female sex workers (FSWs). Using cross-sectional data from 1,022 FSWs in Guangxi, China, we examined how different forms of support from diverse sources may influence condom use among FSWs. Friends, coworkers, and stable partners were FSWs' main sources of social support. Social support from diverse sources differently impacts FSWs' condom use. Policymakers need to consider the complicated profile of social support received by FSWs and create supportive environment for FSWs to protect themselves from HIV risks. Reprinted by permission of Taylor & Francis Ltd. JF - Health care for women international AU - Qiao, Shan AU - Li, Xiaoming AU - Zhang, Chen AU - Zhou, Yuejiao AU - Shen, Zhiyong AU - Tang, Zhenzhu AD - Wayne State University ; Vanderbilt University ; Guangxi Center for Disease Control and Prevention Y1 - 2015/07// PY - 2015 DA - Jul 2015 SP - 834 EP - 850 VL - 36 IS - 7 SN - 0739-9332, 0739-9332 KW - Sociology KW - Condoms KW - Sex workers KW - Social support KW - Well-being KW - Policy making KW - HIV KW - China UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1704341620?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+care+for+women+international&rft.atitle=Social+support+and+condom+use+among+female+sex+workers+in+China&rft.au=Qiao%2C+Shan%3BLi%2C+Xiaoming%3BZhang%2C+Chen%3BZhou%2C+Yuejiao%3BShen%2C+Zhiyong%3BTang%2C+Zhenzhu&rft.aulast=Qiao&rft.aufirst=Shan&rft.date=2015-07-01&rft.volume=36&rft.issue=7&rft.spage=834&rft.isbn=&rft.btitle=&rft.title=Health+care+for+women+international&rft.issn=07399332&rft_id=info:doi/10.1080%2F07399332.2014.971952 LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2015-08-17 N1 - Last updated - 2015-08-17 N1 - SubjectsTermNotLitGenreText - 11938 11949 13521; 5703 3617 6220; Condoms; 11556 13682; 13530 13521; 9625 9628; 93 116 30 DO - http://dx.doi.org/10.1080/07399332.2014.971952 ER - TY - JOUR T1 - Violence against Chinese female sex workers from their stable partners: a hierarchical multiple regression analysis AN - 1704341473; 4694344 AB - Limited data are available regarding risk factors that are related to intimate partner violence (IPV) against female sex workers (FSWs) in the context of stable partnerships. Out of the 1,022 FSWs, 743 reported ever having a stable partnership and 430 (more than half) of those reported experiencing IPV. Hierarchical multivariate regression revealed that some characteristics of stable partners (e.g., low education, alcohol use) and relationship stressors (e.g., frequent friction, concurrent partnerships) were independently predictive of IPV against FSWs. Public health professionals who design future violence prevention interventions targeting FSWs need to consider the influence of their stable partners. Reprinted by permission of Taylor & Francis Ltd. JF - Health care for women international AU - Zhang, Chen AU - Li, Xiaoming AU - Su, Shaobing AU - Hong, Yan AU - Zhou, Yuejiao AU - Tang, Zhenzhu AU - Shen, Zhiyong AD - Vanderbilt University ; Wayne State University ; Texas A&M University ; Guangxi Center for Disease Control and Prevention Y1 - 2015/07// PY - 2015 DA - Jul 2015 SP - 797 EP - 815 VL - 36 IS - 7 SN - 0739-9332, 0739-9332 KW - Sociology KW - Sex workers KW - Health care KW - Mental stress KW - Domestic violence KW - China KW - Medical personnel KW - Public health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1704341473?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+care+for+women+international&rft.atitle=Violence+against+Chinese+female+sex+workers+from+their+stable+partners%3A+a+hierarchical+multiple+regression+analysis&rft.au=Zhang%2C+Chen%3BLi%2C+Xiaoming%3BSu%2C+Shaobing%3BHong%2C+Yan%3BZhou%2C+Yuejiao%3BTang%2C+Zhenzhu%3BShen%2C+Zhiyong&rft.aulast=Zhang&rft.aufirst=Chen&rft.date=2015-07-01&rft.volume=36&rft.issue=7&rft.spage=797&rft.isbn=&rft.btitle=&rft.title=Health+care+for+women+international&rft.issn=07399332&rft_id=info:doi/10.1080%2F07399332.2014.909432 LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2015-08-17 N1 - Last updated - 2015-08-17 N1 - SubjectsTermNotLitGenreText - 11556 13682; 3708 13325; 10449 5772; 7884 13682; 5775 13521; 7953 7954; 93 116 30 DO - http://dx.doi.org/10.1080/07399332.2014.909432 ER - TY - JOUR T1 - Predictors of consistent condom use among Chinese female Sex workers: an application of the protection motivation theory AN - 1704339771; 4694345 AB - We utilized Protection Motivation Theory to assess predictors of intention and behavior of consistent condom use among Chinese female sex workers (FSWs). A self-administered questionnaire was used in a cross-sectional survey among 700 FSWs in Guangxi, China. Multivariate logistic regression analysis indicated that extrinsic and intrinsic rewards, self-efficacy, and response costs predicted consistent condom use intention and behavior among FSWs. Sexually transmitted infection/ HIV prevention programs need to reduce FSWs' perceptions of positive extrinsic rewards and intrinsic rewards for engaging in consistent condom use, reduce FSWs' perception of response costs for using a condom, and increase condom use self-efficacy among FSWs. Reprinted by permission of Taylor & Francis Ltd. JF - Health care for women international AU - Zhang, Liying AU - Li, Xiaoming AU - Zhou, Yuejiao AU - Lin, Danhua AU - Su, Shaobing AU - Zhang, Chen AU - Stanton, Bonita AD - Wayne State University ; Guangxi Center for Disease Control and Prevention ; Beijing Normal University ; Vanderbilt University Y1 - 2015/07// PY - 2015 DA - Jul 2015 SP - 816 EP - 833 VL - 36 IS - 7 SN - 0739-9332, 0739-9332 KW - Sociology KW - Sexuality KW - Condoms KW - Sex workers KW - Regression analysis KW - Females KW - HIV KW - China UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1704339771?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+care+for+women+international&rft.atitle=Predictors+of+consistent+condom+use+among+Chinese+female+Sex+workers%3A+an+application+of+the+protection+motivation+theory&rft.au=Zhang%2C+Liying%3BLi%2C+Xiaoming%3BZhou%2C+Yuejiao%3BLin%2C+Danhua%3BSu%2C+Shaobing%3BZhang%2C+Chen%3BStanton%2C+Bonita&rft.aulast=Zhang&rft.aufirst=Liying&rft.date=2015-07-01&rft.volume=36&rft.issue=7&rft.spage=816&rft.isbn=&rft.btitle=&rft.title=Health+care+for+women+international&rft.issn=07399332&rft_id=info:doi/10.1080%2F07399332.2014.942902 LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2015-08-17 N1 - Last updated - 2015-08-17 N1 - SubjectsTermNotLitGenreText - Condoms; 11556 13682; 4865 11538; 5703 3617 6220; 10739 12228 10919; 11579 11538; 93 116 30 DO - http://dx.doi.org/10.1080/07399332.2014.942902 ER - TY - JOUR T1 - Psychological stressors in the context of commercial sex among female sex workers in China AN - 1704339750; 4694342 AB - Because of the illegality and stigma associated with female sex workers (FSWs) in China, data were limited regarding their psychological stressors examined through the lens of occupational health. Analyzing qualitative data from 16 gatekeepers and 38 FSWs, we explored these stressors in the context of commercial sex in China. We found that FSWs faced a continuum of stressors that resulted from poverty, limited employment, lack of social protection, violence perpetrated by clients, and limited social support from peers and stable partners. We call for empowerment and a structural approach to address the needs of FSWs to improve their psychological well-being. Reprinted by permission of Taylor & Francis Ltd. JF - Health care for women international AU - Zhang, Chen AU - Hong, Yan AU - Li, Xiaoming AU - Qiao, Shan AU - Zhou, Yuejiao AU - Su, Shaobing AD - Vanderbilt University ; Texas A&M University ; Wayne State University ; Guangxi Center for Disease Control and Prevention Y1 - 2015/07// PY - 2015 DA - Jul 2015 SP - 753 EP - 767 VL - 36 IS - 7 SN - 0739-9332, 0739-9332 KW - Sociology KW - Sex workers KW - Social support KW - Poverty KW - Feminism KW - Commercial workers KW - Violence KW - China UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1704339750?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+care+for+women+international&rft.atitle=Psychological+stressors+in+the+context+of+commercial+sex+among+female+sex+workers+in+China&rft.au=Zhang%2C+Chen%3BHong%2C+Yan%3BLi%2C+Xiaoming%3BQiao%2C+Shan%3BZhou%2C+Yuejiao%3BSu%2C+Shaobing&rft.aulast=Zhang&rft.aufirst=Chen&rft.date=2015-07-01&rft.volume=36&rft.issue=7&rft.spage=753&rft.isbn=&rft.btitle=&rft.title=Health+care+for+women+international&rft.issn=07399332&rft_id=info:doi/10.1080%2F07399332.2013.838247 LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2015-08-17 N1 - Last updated - 2015-08-17 N1 - SubjectsTermNotLitGenreText - 11556 13682; 2540 13682; 11938 11949 13521; 4867 6203; 9962; 13325; 93 116 30 DO - http://dx.doi.org/10.1080/07399332.2013.838247 ER - TY - JOUR T1 - Primary Care Providersʼ Recommendations for Hypertension Prevention, DocStyles Survey, 2012 AN - 1701262442 AB - Healthy behaviors, including maintaining an ideal body weight, eating a healthy diet, being physically active, limiting alcohol intake, and not smoking, can help prevent hypertension. The objective of this study was to determine the prevalence of recommending these behaviors to patients by primary care providers (PCPs) and to assess what PCP characteristics, if any, were associated with making the recommendations. DocStyles 2012, a Web based panel survey, was used to assess PCPsʼ demographic characteristics, health-related behaviors, practice setting, and prevalence of making selected recommendations to prevent hypertension. Logistic regression was used to calculate the odds of making all 6 recommendations, by demographic, professional, or personal health behavior characteristics. Most PCPs recommended healthy behaviors to their adult patients to prevent hypertension. PCPsʼ own healthy behaviors were associated with their recommendations. Preventing hypertension is a multifactorial effort, and in the clinical environment, PCPs have frequent opportunities to model and promote healthy lifestyles to their patients. JF - Journal of Primary Care & Community Health AU - Ayala, Carma AU - Loustalot, Fleetwood AD - National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA ; Fang, Jing; National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA Y1 - 2015/07// PY - 2015 DA - Jul 2015 SP - 170 EP - 176 CY - Thousand Oaks PB - SAGE PUBLICATIONS, INC. VL - 6 IS - 3 SN - 2150-1319 KW - Medical Sciences KW - primary care providers KW - hypertension (high blood pressure) KW - prevention KW - healthy behaviors KW - Blood pressure KW - Healthy habits KW - Hypertension KW - Patient care KW - Primary health care KW - Smoking KW - Body weight KW - Characteristics KW - Clinical guidelines KW - Demographic aspects KW - Diet KW - Eating KW - Health behaviour KW - Health professionals KW - Healthy food UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1701262442?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Primary+Care+%26+Community+Health&rft.atitle=Primary+Care+Providers%CA%BC+Recommendations+for+Hypertension+Prevention%2C+DocStyles+Survey%2C+2012&rft.au=Fang%2C+Jing%3BAyala%2C+Carma%3BLoustalot%2C+Fleetwood&rft.aulast=Fang&rft.aufirst=Jing&rft.date=2015-07-01&rft.volume=6&rft.issue=3&rft.spage=170&rft.isbn=&rft.btitle=&rft.title=Journal+of+Primary+Care+%26+Community+Health&rft.issn=21501319&rft_id=info:doi/10.1177%2F2150131915568997 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2015-09-22 N1 - Last updated - 2016-05-16 DO - http://dx.doi.org/10.1177/2150131915568997 ER - TY - JOUR T1 - What we don't know can hurt us: Nonresponse bias assessment in birth defects research. AN - 1698034261; 26173046 AB - Nonresponse bias assessment is an important and underutilized tool in survey research to assess potential bias due to incomplete participation. This study illustrates a nonresponse bias sensitivity assessment using a survey on perceived barriers to care for children with orofacial clefts in North Carolina. Children born in North Carolina between 2001 and 2004 with an orofacial cleft were eligible for inclusion. Vital statistics data, including maternal and child characteristics, were available on all eligible subjects. Missing 'responses' from nonparticipants were imputed using assumptions based on the distribution of responses, survey method (mail or phone), and participant maternal demographics. Overall, 245 of 475 subjects (51.6%) responded to either a mail or phone survey. Cost as a barrier to care was reported by 25.0% of participants. When stratified by survey type, 28.3% of mail respondents and 17.2% of phone respondents reported cost as a barrier. Under various assumptions, the bias-adjusted estimated prevalence of cost as barrier to care ranged from 16.1% to 30.0%. Maternal age, education, race, and marital status at time of birth were not associated with subjects reporting cost as a barrier. As survey response rates continue to decline, the importance of assessing the potential impact of nonresponse bias has become more critical. Birth defects research is particularly conducive to nonresponse bias analysis, especially when birth defect registries and birth certificate records are used. Future birth defect studies which use population-based surveillance data and have incomplete participation could benefit from this type of nonresponse bias assessment. Birth Defects Research (Part A) 103:603-609, 2015. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc. JF - Birth defects research. Part A, Clinical and molecular teratology AU - Strassle, Paula D AU - Cassell, Cynthia H AU - Shapira, Stuart K AU - Tinker, Sarah C AU - Meyer, Robert E AU - Grosse, Scott D AD - Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina. ; National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia. ; North Carolina Birth Defects Monitoring Program, State Center for Health Statistics, North Carolina Division of Public Health, Raleigh, North Carolina. Y1 - 2015/07// PY - 2015 DA - July 2015 SP - 603 EP - 609 VL - 103 IS - 7 KW - Index Medicus KW - nonresponse bias KW - response rates KW - barriers to care KW - orofacial clefts KW - Humans KW - North Carolina KW - Cleft Palate KW - Cleft Lip KW - Bias (Epidemiology) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1698034261?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Birth+defects+research.+Part+A%2C+Clinical+and+molecular+teratology&rft.atitle=What+we+don%27t+know+can+hurt+us%3A+Nonresponse+bias+assessment+in+birth+defects+research.&rft.au=Strassle%2C+Paula+D%3BCassell%2C+Cynthia+H%3BShapira%2C+Stuart+K%3BTinker%2C+Sarah+C%3BMeyer%2C+Robert+E%3BGrosse%2C+Scott+D&rft.aulast=Strassle&rft.aufirst=Paula&rft.date=2015-07-01&rft.volume=103&rft.issue=7&rft.spage=603&rft.isbn=&rft.btitle=&rft.title=Birth+defects+research.+Part+A%2C+Clinical+and+molecular+teratology&rft.issn=1542-0760&rft_id=info:doi/10.1002%2Fbdra.23408 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2016-04-15 N1 - Date created - 2015-07-21 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Cited By: Med Care. 2002 Mar;40(3):190-200 [11880792] Epidemiology. 2009 Nov;20(6):872-9 [19704374] JAMA. 2012 May 2;307(17):1805-6 [22550194] Cleft Palate Craniofac J. 2012 May;49(3):262-9 [21740175] Health Serv Res. 2013 Jun;48(3):913-30 [23046097] Health Serv Res. 2013 Jun;48(3):905-12 [23656501] Birth Defects Res A Clin Mol Teratol. 2013 Oct;97(10):685-95 [24039055] Birth Defects Res A Clin Mol Teratol. 2014 Nov;100(11):837-47 [25200965] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1002/bdra.23408 ER - TY - JOUR T1 - Factors associated with inpatient hospitalizations among patients aged 1 to 64 years with congenital heart defects, Arkansas 2006 to 2011. AN - 1698030957; 26172576 AB - Individuals with congenital heart defects (CHDs) have high hospital resource use. We sought to identify factors associated with hospital costs and multiple hospitalizations among individuals with CHDs. Data from the 2006 to 2011 Healthcare Cost and Utilization Project Arkansas State Inpatient Databases were linked across encrypted patient identifiers to develop a cohort of Arkansas residents aged 1 to 64 years who were hospitalized at least once with a CHD during this time period. Infants were excluded because patient identifiers were missing for 18 to 52% each year. CHDs were identified using principal and secondary International Classification of Diseases, Ninth Revision, Clinical Modification diagnoses codes. All hospitalizations of individuals ever admitted with a CHD were included. Mean and median patient-level costs were estimated; the association of hospital costs and patient readmissions were examined with linear and logistic regression. There were 1,185,868 inpatient hospitalizations of Arkansas residents aged 1 to 64 years between 2006 and 2011; these were accrued by 603,925 patients. Of those, 2542 patients (0.42%) had at least one hospitalization with a CHD diagnosis. Total costs for these 2542 patients were $126,999,837 and they accumulated 7898 hospitalizations. Factors associated with increased costs included patient age, CHD type, cardiac procedures, and comorbidities. Factors associated with hospital readmission within 1 year included age, CHD type, expected payer, and comorbidities. Individuals with CHDs in Arkansas experience variation in hospital use and costs by patient characteristics. Future research should investigate factors associated with readmissions, cardiac procedures, and comorbidities, as these are strongly associated with hospital costs. Birth Defects Research (Part A) 103:589-596, 2015. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc. JF - Birth defects research. Part A, Clinical and molecular teratology AU - Simeone, Regina M AU - Oster, Matthew E AU - Hobbs, Charlotte A AU - Robbins, James M AU - Thomas Collins, R AU - Honein, Margaret A AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. ; University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA. Y1 - 2015/07// PY - 2015 DA - July 2015 SP - 589 EP - 596 VL - 103 IS - 7 KW - Index Medicus KW - Healthcare Cost and Utilization Project KW - One-year readmission KW - Congenital heart defects KW - Person-level KW - Arkansas KW - hospital costs KW - Infant KW - Young Adult KW - Humans KW - Adult KW - Middle Aged KW - Child KW - Adolescent KW - Male KW - Female KW - Child, Preschool KW - Hospitalization KW - Heart Defects, Congenital -- physiopathology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1698030957?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Birth+defects+research.+Part+A%2C+Clinical+and+molecular+teratology&rft.atitle=Factors+associated+with+inpatient+hospitalizations+among+patients+aged+1+to+64+years+with+congenital+heart+defects%2C+Arkansas+2006+to+2011.&rft.au=Simeone%2C+Regina+M%3BOster%2C+Matthew+E%3BHobbs%2C+Charlotte+A%3BRobbins%2C+James+M%3BThomas+Collins%2C+R%3BHonein%2C+Margaret+A&rft.aulast=Simeone&rft.aufirst=Regina&rft.date=2015-07-01&rft.volume=103&rft.issue=7&rft.spage=589&rft.isbn=&rft.btitle=&rft.title=Birth+defects+research.+Part+A%2C+Clinical+and+molecular+teratology&rft.issn=1542-0760&rft_id=info:doi/10.1002%2Fbdra.23402 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2016-04-15 N1 - Date created - 2015-07-21 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Cited By: J Am Coll Cardiol. 2009 Jul 28;54(5):460-7 [19628123] Pediatrics. 1998 Jul;102(1 Pt 1):35-43 [9651411] Circ Cardiovasc Qual Outcomes. 2011 May;4(3):306-12 [21505154] Pediatrics. 2011 Jun;127(6):e1482-9 [21576309] Pediatrics. 2011 Nov;128(5):e1259-67 [21987707] Vital Health Stat 2. 2012 Jan;(154):1-65 [22783637] Birth Defects Res A Clin Mol Teratol. 2013 Feb;97(2):87-94 [23404870] Pediatrics. 2013 May;131(5):e1502-8 [23610203] Pediatrics. 2014 Mar;133(3):e553-60 [24567024] Circulation. 2014 Aug 26;130(9):749-56 [24944314] Birth Defects Res A Clin Mol Teratol. 2014 Dec;100(12):934-43 [24975483] J Am Coll Cardiol. 2001 Apr;37(5):1170-5 [11300418] Med Care. 1998 Jan;36(1):8-27 [9431328] Birth Defects Res A Clin Mol Teratol. 2015 Sep;103(9):814-20 [26069215] Pediatrics. 2005 Sep;116(3):689-95 [16140709] J Perinatol. 2005 Nov;25(11):737-42 [16163368] Circulation. 2007 Jan 16;115(2):163-72 [17210844] Am J Cardiol. 2007 Mar 15;99(6):839-43 [17350378] Congenit Heart Dis. 2007 Sep-Oct;2(5):319-26 [18377447] J Pediatr. 2008 Dec;153(6):807-13 [18657826] Cardiol Young. 2008 Dec;18 Suppl 2:92-100 [19063779] Acta Paediatr. 2009 Mar;98(3):472-7 [19046347] Circulation. 2009 Aug 4;120(5):447-58 [19581492] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1002/bdra.23402 ER - TY - JOUR T1 - Immunity to polio, measles and rubella in women of child-bearing age and estimated congenital rubella syndrome incidence, Cambodia, 2012 AN - 1694984149; PQ0001623352 AB - Significant gaps in immunity to polio, measles, and rubella may exist in adults in Cambodia and threaten vaccine-preventable disease (VPD) elimination and control goals, despite high childhood vaccination coverage. We conducted a nationwide serological survey during November-December 2012 of 2154 women aged 15-39 years to assess immunity to polio, measles, and rubella and to estimate congenital rubella syndrome (CRS) incidence. Measles and rubella antibodies were detected by IgG ELISA and polio antibodies by microneutralization testing. Age-structured catalytic models were fitted to rubella serological data to predict CRS cases. Overall, 29.8% of women lacked immunity to at least one poliovirus (PV); seroprevalence to PV1, PV2 and PV3 was 85.9%, 93.4% and 83.3%, respectively. Rubella and measles antibody seroprevalence was 73.3% and 95.9%, respectively. In the 15-19 years age group, 48.2% [95% confidence interval (CI) 42.4-54.1] were susceptible to either PV1 or PV3, and 40.3% (95% CI 33.0-47.5) to rubella virus. Based on rubella antibody seroprevalence, we estimate that >600 infants are born with CRS in Cambodia annually. Significant numbers of Cambodian women are still susceptible to polio and rubella, especially those aged 15-19 years, emphasizing the need to include adults in VPD surveillance and a potential role for vaccination strategies targeted at adults. JF - Epidemiology and Infection AU - Mao, B AU - CHHENG, K AU - Wannemuehler, K AU - VYNNYCKY, E AU - Buth, S AU - SOEUNG, S C AU - Reef, S AU - Weldon, W AU - Quick, L AU - Gregory, C J AD - University of Health Sciences, Phnom Penh, Cambodia, hgk4@cdc.gov PY - 2015 SP - 1858 EP - 1867 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 143 IS - 9 SN - 0950-2688, 0950-2688 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Poliovirus KW - Enzyme-linked immunosorbent assay KW - Age KW - Data processing KW - Measles KW - Immunity KW - Children KW - Vaccination KW - Rubella KW - Models KW - Rubella virus KW - Serological surveys KW - Cambodia KW - Congenital rubella KW - Immunoglobulin G KW - Age groups KW - Vaccines KW - Females KW - Infants KW - H 4000:Food and Drugs KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1694984149?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Immunity+to+polio%2C+measles+and+rubella+in+women+of+child-bearing+age+and+estimated+congenital+rubella+syndrome+incidence%2C+Cambodia%2C+2012&rft.au=Mao%2C+B%3BCHHENG%2C+K%3BWannemuehler%2C+K%3BVYNNYCKY%2C+E%3BButh%2C+S%3BSOEUNG%2C+S+C%3BReef%2C+S%3BWeldon%2C+W%3BQuick%2C+L%3BGregory%2C+C+J&rft.aulast=Mao&rft.aufirst=B&rft.date=2015-07-01&rft.volume=143&rft.issue=9&rft.spage=1858&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268814002817 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-07-01 N1 - Number of references - 32 N1 - Last updated - 2016-01-21 N1 - SubjectsTermNotLitGenreText - Age; Enzyme-linked immunosorbent assay; Data processing; Measles; Immunity; Children; Rubella; Vaccination; Models; Serological surveys; Congenital rubella; Immunoglobulin G; Infants; Poliovirus; Age groups; Females; Vaccines; Rubella virus; Cambodia DO - http://dx.doi.org/10.1017/S0950268814002817 ER - TY - JOUR T1 - Trends and characteristics of heroin overdoses in Wisconsin, 2003-2012. AN - 1686414308; 25935735 AB - Heroin abuse has increased substantially during the past decade in the United States. This study describes trends and demographic shifts of heroin overdoses and heroin-related fatalities in Wisconsin and contrasts these with prescription opioid overdoses. This study was cross-sectional using databases of emergency department (ED) visits, hospital admissions, and death certificates in Wisconsin, United States, during 2003-2012. Cases were Wisconsin residents treated for heroin or prescription opioid overdose, and residents who died of heroin-related drug poisoning. Primary measurements were rates over time and by geographic region, and rates and rate ratios for selected demographic characteristics. During 2003-2012, age-adjusted rates of heroin overdoses treated in EDs increased from 1.0 to 7.9/100,000 persons; hospitalized heroin overdoses increased from 0.7 to 3.5/100,000. Whites accounted for 68% of hospitalized heroin overdoses during 2003-2007 but 80% during 2008-2012. Heroin-related deaths were predominantly among urban residents; however, rural fatalities accounted for zero deaths in 2003 but 31 (17%) deaths in 2012. Among patients aged 18-34 years, those hospitalized with heroin overdose were more often men (73.0% versus 54.9%), uninsured (44.2% versus 29.9%), and urban (84.3% versus 73.2%) than those with prescription opioid overdose. Rates of ED visits for heroin overdose in this age group exceeded rates for prescription opioid overdose in 2012 (26.1/100,000 versus 12.6/100,000 persons, respectively). An epidemic of heroin abuse is characterized by demographic shifts toward whites and rural residents. Rates of heroin overdose in younger persons now exceed rates of prescription opioid overdose. Published by Elsevier Ireland Ltd. JF - Drug and alcohol dependence AU - Meiman, Jon AU - Tomasallo, Carrie AU - Paulozzi, Leonard AD - Epidemic Intelligence Service, Centers for Disease Control and Prevention, Wisconsin Division of Public Health, 1 West Wilson Street, Room 150, Madison, WI 53703, United States. Electronic address: xdf5@cdc.gov. ; Wisconsin Division of Public Health, 1 West Wilson Street, Room 150, Madison, WI 53703, United States. Electronic address: Carrie.Tomasallo@dhs.wisconsin.gov. ; National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, CDC El Paso Quarantine Station, 601 Sunland Park Drive, Suite 200, El Paso, TX 79912, United States. Electronic address: LBP4@cdc.gov. Y1 - 2015/07/01/ PY - 2015 DA - 2015 Jul 01 SP - 177 EP - 184 VL - 152 KW - Analgesics, Opioid KW - 0 KW - Heroin KW - 70D95007SX KW - Index Medicus KW - Mortality KW - Prescription opioids KW - Overdose KW - Wisconsin KW - Young Adult KW - Age Factors KW - Urban Population -- statistics & numerical data KW - Sex Factors KW - Humans KW - Rural Population -- statistics & numerical data KW - Aged KW - Cross-Sectional Studies KW - Heroin Dependence -- epidemiology KW - Wisconsin -- epidemiology KW - Adult KW - Emergency Service, Hospital -- statistics & numerical data KW - Middle Aged KW - Adolescent KW - Time Factors KW - Female KW - Male KW - Analgesics, Opioid -- poisoning KW - Drug Overdose -- mortality KW - Heroin -- poisoning KW - Drug Overdose -- epidemiology KW - Hospitalization -- trends UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1686414308?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Drug+and+alcohol+dependence&rft.atitle=Trends+and+characteristics+of+heroin+overdoses+in+Wisconsin%2C+2003-2012.&rft.au=Meiman%2C+Jon%3BTomasallo%2C+Carrie%3BPaulozzi%2C+Leonard&rft.aulast=Meiman&rft.aufirst=Jon&rft.date=2015-07-01&rft.volume=152&rft.issue=8&rft.spage=623&rft.isbn=&rft.btitle=&rft.title=Annals+of+Epidemiology&rft.issn=10472797&rft_id=info:doi/10.1016%2Fj.annepidem.2011.03.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2016-02-08 N1 - Date created - 2015-06-06 N1 - Date revised - 2017-01-14 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1016/j.drugalcdep.2015.04.002 ER - TY - JOUR T1 - Using Behavioral Risk Factor Surveillance System Data to Estimate the Percentage of the Population Meeting US Department of Agriculture Food Patterns Fruit and Vegetable Intake Recommendations AN - 1701475699; PQ0001732767 AB - Most Americans do not eat enough fruits and vegetables with significant variation by state. State-level self-reported frequency of fruit and vegetable consumption is available from the Centers for Disease Control and Prevention's Behavioral Risk Factor Surveillance System (BRFSS). However, BRFSS cannot be used to directly compare states' progress toward national goals because of incongruence in units used to measure intake and because distributions from frequency data are not reflective of usual intake. To help states track progress, we developed scoring algorithms from external data and applied them to BRFSS 2011 data to estimate the percentage of each state's adult population meeting US Department of Agriculture Food Patterns fruit and vegetable intake recommendations. We used 24-hour dietary recall data from the National Health and Nutrition Examination Survey, 2007-2010, to fit sex- and age-specific models that estimate probabilities of meeting recommendations as functions of reported consumption frequency, race/ethnicity, and poverty-income ratio adjusting for intraindividual variation. Regression parameters derived from these models were applied to BRFSS to estimate the percentage meeting recommendations. We estimate that 7%-18% of state populations met fruit recommendations and 5%-12% met vegetable recommendations. Our method provides a new tool for states to track progress toward meeting dietary recommendations. JF - American Journal of Epidemiology AU - Moore, Latetia V AU - Dodd, Kevin W AU - Thompson, Frances E AU - Grimm, Kirsten A AU - Kim, Sonia A AU - Scanlon, Kelley S AD - Correspondence to Dr. Latetia V. Moore, Division of Nutrition, Physical Activity, and Obesity, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Mailstop F77, Atlanta, GA 30341, lvmoore@cdc.gov Y1 - 2015/06/15/ PY - 2015 DA - 2015 Jun 15 SP - 979 EP - 988 PB - Oxford University Press, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 181 IS - 12 SN - 0002-9262, 0002-9262 KW - Risk Abstracts KW - fruits KW - recommended intake KW - states KW - vegetables KW - Diets KW - Agriculture KW - Fruits KW - Prevention KW - Risk factors KW - Disease control KW - Nutrition KW - Ethnic groups KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1701475699?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Epidemiology&rft.atitle=Using+Behavioral+Risk+Factor+Surveillance+System+Data+to+Estimate+the+Percentage+of+the+Population+Meeting+US+Department+of+Agriculture+Food+Patterns+Fruit+and+Vegetable+Intake+Recommendations&rft.au=Moore%2C+Latetia+V%3BDodd%2C+Kevin+W%3BThompson%2C+Frances+E%3BGrimm%2C+Kirsten+A%3BKim%2C+Sonia+A%3BScanlon%2C+Kelley+S&rft.aulast=Moore&rft.aufirst=Latetia&rft.date=2015-06-15&rft.volume=181&rft.issue=12&rft.spage=979&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Epidemiology&rft.issn=00029262&rft_id=info:doi/10.1093%2Faje%2Fkwu461 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-08-01 N1 - Last updated - 2015-09-03 N1 - SubjectsTermNotLitGenreText - Agriculture; Diets; Fruits; Prevention; Risk factors; Disease control; Nutrition; Ethnic groups DO - http://dx.doi.org/10.1093/aje/kwu461 ER - TY - JOUR T1 - Integration of Novel Low-Cost Colorimetric, Laser Photometric, and Visual Fluorescent Techniques for Rapid Identification of Falsified Medicines in Resource-Poor Areas: Application to Artemether-Lumefantrine AN - 1727682899; PQ0002197809 AB - The availability of falsified antimalarial drugs can be reduced with effective drug regulatory agencies and proper enforcement. Fundamental to these agencies taking action, rapid identification must be made as soon as they appear in the market place. Since falsified antimalarials occur mostly in developing countries, performing drug analysis presents itself with unique challenges. A fundamental factor in choosing a useful technique is affordability and simplicity. Therefore, we suggest a three-tiered drug evaluation strategy for identifying a falsified drug in resource-poor areas. Tier I is a simple comparison of a tablet's weight and dimensions with official specifications. Tier II uses inexpensive photometric devices (laser and fluorescence) to evaluate a tablet. Suspicious samples from Tier I and II assessments are then subjected to a colorimetric assay for active ingredients identification and quantification. In this article, we evaluate a novel colorimetric assay for the simultaneous assessment of both lumefantrine and artemether in co-formulated Coartem " tablets, and integrate the method with two novel, low-cost, fluorescence and laser photometric devices. Image analysis software is used for the assessments. Although artemether-lumefantrine is used as an example, the strategy may be adapted to other medicines. JF - American Journal of Tropical Medicine and Hygiene AU - Green, Michael D AU - Hostetler, Dana M AU - Nettey, Henry AU - Swamidoss, Isabel AU - Ranieri, Nicola AU - Newton, Paul N AD - Division of Parasitic Diseases and Malaria, Center for Disease Control, Atlanta, Georgia, mgreen@cdc.gov Y1 - 2015/06// PY - 2015 DA - June 2015 SP - 8 EP - 16 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 92 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Fluorescence KW - Tablets KW - Surveillance and enforcement KW - Colorimetry KW - Image processing KW - Drug development KW - Artemether KW - Computer programs KW - Integration KW - software KW - Medicine KW - Lasers KW - Governments KW - Hygiene KW - Drugs KW - Developing countries KW - K 03340:Effects of Physical & Chemical Factors KW - Q1 08604:Stock assessment and management KW - Q5 08524:Public health, medicines, dangerous organisms KW - J 02300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727682899?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Integration+of+Novel+Low-Cost+Colorimetric%2C+Laser+Photometric%2C+and+Visual+Fluorescent+Techniques+for+Rapid+Identification+of+Falsified+Medicines+in+Resource-Poor+Areas%3A+Application+to+Artemether-Lumefantrine&rft.au=Green%2C+Michael+D%3BHostetler%2C+Dana+M%3BNettey%2C+Henry%3BSwamidoss%2C+Isabel%3BRanieri%2C+Nicola%3BNewton%2C+Paul+N&rft.aulast=Green&rft.aufirst=Michael&rft.date=2015-06-01&rft.volume=92&rft.issue=&rft.spage=8&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0832 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-09-29 N1 - SubjectsTermNotLitGenreText - Surveillance and enforcement; Governments; Lasers; Medicine; Hygiene; Developing countries; Drugs; Integration; Computer programs; software; Fluorescence; Tablets; Image processing; Colorimetry; Drug development; Artemether DO - http://dx.doi.org/10.4269/ajtmh.14-0832 ER - TY - JOUR T1 - Real-Time PCR and Sequencing Assays for Rapid Detection and Identification of Avian Schistosomes in Environmental Samples AN - 1701482478; PQ0001679616 AB - Cercarial dermatitis, also known as swimmer's itch, is an allergenic skin reaction followed by intense itching caused by schistosome cercariae penetrating human skin. Cercarial dermatitis outbreaks occur globally and are frequently associated with freshwater lakes and are occasionally associated with marine or estuarine waters where birds reside year-round or where migratory birds reside. In this study, a broadly reactive TaqMan assay targeting 18S rRNA gene (ribosomal DNA [rDNA]) sequences that was based on a genetically diverse panel of schistosome isolates representing 13 genera and 20 species (the 18S rDNA TaqMan assay) was developed. A PCR assay was also developed to amplify a 28S rDNA region for subsequent sequencing to identify schistosomes. When applied to surface water samples seeded with Schistosoma mansoni cercariae, the 18S rDNA TaqMan assay enabled detection at a level of 5 S. mansoni cercariae in 100 liters of lake water. The 18S rDNA TaqMan and 28S rDNA PCR sequencing assays were also applied to 100-liter water samples collected from lakes in Nebraska and Wisconsin where there were reported dermatitis outbreaks. Avian schistosome DNA was detected in 11 of 34 lake water samples using the TaqMan assay. Further 28S rDNA sequence analysis of positive samples confirmed the presence of avian schistosome DNA and provided a preliminary identification of the avian schistosomes in 10 of the 11 samples. These data indicate that the broadly schistosome-reactive TaqMan assay can be effective for rapid screening of large-volume water samples for detection of avian schistosomes, thereby facilitating timely response actions to mitigate or prevent dermatitis outbreaks. Additionally, samples positive by the 18S rDNA TaqMan assay can be further assayed using the 28S rDNA sequencing assay to both confirm the presence of schistosomes and contribute to their identification. JF - Applied and Environmental Microbiology AU - Jothikumar, Narayanan AU - Mull, Bonnie J AU - Brant, Sara V AU - Loker, Eric S AU - Collinson, Jeremy AU - Secor, W Evan AU - Hill, Vincent R AD - Waterborne Disease Prevention Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, jin2@cdc.gov. PY - 2015 SP - 4207 EP - 4215 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 81 IS - 12 SN - 0099-2240, 0099-2240 KW - Microbiology Abstracts A: Industrial & Applied Microbiology KW - Schistosoma mansoni KW - rRNA 18S KW - Lakes KW - Skin KW - Data processing KW - Freshwater environments KW - Surface water KW - Nucleotide sequence KW - Recruitment KW - Polymerase chain reaction KW - Dermatitis KW - A 01340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1701482478?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Real-Time+PCR+and+Sequencing+Assays+for+Rapid+Detection+and+Identification+of+Avian+Schistosomes+in+Environmental+Samples&rft.au=Jothikumar%2C+Narayanan%3BMull%2C+Bonnie+J%3BBrant%2C+Sara+V%3BLoker%2C+Eric+S%3BCollinson%2C+Jeremy%3BSecor%2C+W+Evan%3BHill%2C+Vincent+R&rft.aulast=Jothikumar&rft.aufirst=Narayanan&rft.date=2015-06-01&rft.volume=81&rft.issue=12&rft.spage=4207&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/10.1128%2FAEM.00750-15 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-08-01 N1 - Number of references - 31 N1 - Last updated - 2016-01-21 N1 - SubjectsTermNotLitGenreText - rRNA 18S; Lakes; Data processing; Skin; Surface water; Freshwater environments; Nucleotide sequence; Recruitment; Polymerase chain reaction; Dermatitis; Schistosoma mansoni DO - http://dx.doi.org/10.1128/AEM.00750-15 ER - TY - JOUR T1 - Decreasing Trend in Tobacco-Related Cancer Incidence, United States 2005-2009 AN - 1691295869; PQ0001590970 AB - More than 1 in 3 cancer-related deaths are associated with tobacco use; these include cancers of the lung and bronchus, oral cavity and pharynx, larynx, esophagus, stomach, pancreas, kidney and renal pelvis, urinary bladder, and cervix, and acute myeloid leukemia. In order to characterize the current cancer burden due to tobacco use, this study provides recent trends in tobacco-related cancer incidence across the US. We analyzed data from CDC's National Program of Cancer Registries and NCI's Surveillance, Epidemiology and End Results Program, covering 100 % of the US population during 2005-2009. Age-adjusted incidence rates, 95 % confidence intervals and annual percent change were calculated for each state, the District of Columbia, and the US. Tobacco-related cancer incidence in the US decreased significantly from 152.9 (per 100,000 persons) in 2005 to 145.8 in 2009. Men had higher incidence rates, but a greater decrease in tobacco-related cancers per year over the 5-year time period (-1.4 % in men, compared to -0.8 % in women). Incidence rates decreased the most per year for larynx (-2.4 %), lung and bronchus (-1.9 %) and stomach (-1.5 %) cancers during the study period. Tobacco-related cancer incidence trends varied by state. While tobacco-related cancer incidence in the United States decreased overall from 2005 to 2009, tobacco continued to account for a large cancer burden. Our findings suggest that continued efforts in tobacco prevention and control are needed to further reduce tobacco-related cancer burden in general and among targeted sub-populations in the US. JF - Journal of Community Health AU - Underwood, JMichael AU - Richards, Thomas B AU - Henley, SJane AU - Momin, Behnoosh AU - Houston, Keisha AU - Rolle, Italia AU - Holmes, Carissa AU - Stewart, Sherri L AD - Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway, N.E., Atlanta, GA, 30341, USA, jmunderwood@cdc.gov Y1 - 2015/06// PY - 2015 DA - Jun 2015 SP - 414 EP - 418 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 40 IS - 3 SN - 0094-5145, 0094-5145 KW - Health & Safety Science Abstracts KW - Renal KW - Mortality KW - Leukemia KW - USA KW - Prevention KW - Lung KW - Urinary bladder KW - Tobacco KW - Kidney KW - Cancer KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1691295869?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Community+Health&rft.atitle=Decreasing+Trend+in+Tobacco-Related+Cancer+Incidence%2C+United+States+2005-2009&rft.au=Underwood%2C+JMichael%3BRichards%2C+Thomas+B%3BHenley%2C+SJane%3BMomin%2C+Behnoosh%3BHouston%2C+Keisha%3BRolle%2C+Italia%3BHolmes%2C+Carissa%3BStewart%2C+Sherri+L&rft.aulast=Underwood&rft.aufirst=JMichael&rft.date=2015-06-01&rft.volume=40&rft.issue=3&rft.spage=414&rft.isbn=&rft.btitle=&rft.title=Journal+of+Community+Health&rft.issn=00945145&rft_id=info:doi/10.1007%2Fs10900-014-9951-6 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-06-01 N1 - Number of references - 20 N1 - Last updated - 2015-07-23 N1 - SubjectsTermNotLitGenreText - Renal; Leukemia; Mortality; Prevention; Urinary bladder; Lung; Kidney; Tobacco; Cancer; USA DO - http://dx.doi.org/10.1007/s10900-014-9951-6 ER - TY - JOUR T1 - U.S. women of childbearing age who are at possible increased risk of a neural tube defect-affected pregnancy due to suboptimal red blood cell folate concentrations, National Health and Nutrition Examination Survey 2007 to 2012. AN - 1690652440; 25884850 AB - Red blood cell (RBC) folate concentrations are a potential biomarker of folate-sensitive neural tube defect (NTD) risk in the population. The purpose of this analysis was to describe women in the U.S. population with RBC folate concentrations below those associated with optimal NTD prevention. We used data from the 2007 to 2012 National Health and Nutrition Examination Survey (NHANES) to assess the RBC folate status of U.S. women of childbearing age relative to risk categories for NTD risk based on RBC folate concentrations. We defined suboptimal RBC folate concentrations as those associated with a prevalence of ≥9 NTDs per 10,000 live births. Among nonpregnant women age 12 to 49 years, 22.8% (95% Confidence Interval: 21.1, 24.6) had suboptimal RBC folate concentrations. Women had greater odds of having a suboptimal RBC folate concentration if they did not use dietary supplements containing folic acid; had mandatorily fortified enriched cereal grain products as their only source of folic acid; were non-Hispanic black or Hispanic; or were current smokers. Based on RBC folate concentrations, we would predict that the majority of U.S. women of reproductive age are not at increased risk for folate sensitive NTDs in the presence of mandatory folic acid fortification. Prevention policies and programs can be aimed at population subgroups identified as having higher predicted risk for folate-sensitive NTDs based on RBC folate concentrations. © 2015 Wiley Periodicals, Inc. JF - Birth defects research. Part A, Clinical and molecular teratology AU - Tinker, Sarah C AU - Hamner, Heather C AU - Qi, Yan Ping AU - Crider, Krista S AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia. ; National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia. Y1 - 2015/06// PY - 2015 DA - June 2015 SP - 517 EP - 526 VL - 103 IS - 6 KW - Biomarkers KW - 0 KW - Folic Acid KW - 935E97BOY8 KW - Index Medicus KW - folic acid KW - neural tube defects KW - fortification KW - NHANES KW - optimal RBC folate concentration KW - Humans KW - Adult KW - Adolescent KW - United States -- epidemiology KW - Female KW - Pregnancy KW - Erythrocytes -- chemistry KW - Folic Acid -- blood KW - Risk Assessment -- statistics & numerical data KW - Risk Assessment -- methods KW - Biomarkers -- blood KW - Neural Tube Defects -- epidemiology KW - Folic Acid -- analysis KW - Nutrition Surveys -- statistics & numerical data UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1690652440?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Child+and+Youth+Care+Forum&rft.atitle=The+Good+Enough+Home%3F+Home+Environment+and+Outcomes+of+Young+Maltreated+Children&rft.au=Robinson%2C+Lara+R%3BBoris%2C+Neil+W%3BHeller%2C+Sherryl+Scott%3BRice%2C+Janet%3BZeanah%2C+Charles+H%3BClark%2C+Cinda%3BHawkins%2C+Shantice&rft.aulast=Robinson&rft.aufirst=Lara&rft.date=2012-02-01&rft.volume=41&rft.issue=1&rft.spage=73&rft.isbn=&rft.btitle=&rft.title=Child+and+Youth+Care+Forum&rft.issn=10531890&rft_id=info:doi/10.1007%2Fs10566-011-9157-3 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2016-03-17 N1 - Date created - 2015-06-22 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Cited By: Lancet. 1991 Jul 20;338(8760):131-7 [1677062] MMWR Recomm Rep. 1992 Sep 11;41(RR-14):1-7 [1522835] N Engl J Med. 1992 Dec 24;327(26):1832-5 [1307234] JAMA. 1995 Dec 6;274(21):1698-702 [7474275] JAMA. 1996 Apr 24;275(16):1233-40 [8601954] Pediatrics. 2005 Sep;116(3):580-6 [16140696] Birth Defects Res A Clin Mol Teratol. 2006 Nov;76(11):747-56 [17051527] Birth Defects Res A Clin Mol Teratol. 2008 Apr;82(4):211-6 [18338391] Am J Clin Nutr. 2008 Jul;88(1):232-46 [18614746] Am J Epidemiol. 2009 Jan 1;169(1):9-17 [18953063] Ann Intern Med. 2009 May 5;150(9):626-31 [19414842] Am J Clin Nutr. 2010 Jan;91(1):64-72 [19828716] Am J Prev Med. 2010 May;38(5):534-42 [20347553] Birth Defects Res A Clin Mol Teratol. 2010 Dec;88(12):1008-16 [20878909] J Nutr. 2011 Jul;141(7):1402-9 [21613453] Epidemiology. 2011 Sep;22(5):731-7 [21659881] J Nutr. 2012 May;142(5):886-93 [22437563] J Nutr. 2013 Jun;143(6):948S-56S [23596165] BMJ. 2014;349:g4554 [25073783] Vital Health Stat 2. 2013 Sep;(161):1-24 [25090154] MMWR Morb Mortal Wkly Rep. 2015 Jan 16;64(1):1-5 [25590678] N Engl J Med. 2007 Jul 12;357(2):135-42 [17625125] N Engl J Med. 1999 Nov 11;341(20):1485-90 [10559448] MMWR Morb Mortal Wkly Rep. 2004 May 7;53(17):362-5 [15129193] Comment In: Birth Defects Res A Clin Mol Teratol. 2015 Jun;103(6):469-70 [25884960] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1002/bdra.23378 ER - TY - JOUR T1 - HIV, Chlamydia, Gonorrhea, and Primary and Secondary Syphilis among American Indians and Alaska Natives Within Indian Health Service Areas in the United States, 2007-2010 AN - 1687668419; PQ0001590980 AB - National rates from human immunodeficiency virus (HIV) and sexually transmitted disease (STD) surveillance may not effectively convey the impact of HIV and STDs on American Indian/Alaska Native (AI/AN) communities. Instead, we compared average annual diagnosis rates per 100,000 population of HIV, chlamydia (CT), gonorrhea (GC), and primary and secondary (P&S) syphilis, from 2007 to 2010, among AI/AN aged greater than or equal to 13 years residing in 625 counties in the 12 Indian Health Service Areas, all AI/AN, and all races/ethnicities to address this gap. AI/AN comprised persons reported as AI/AN only, with or without Hispanic ethnicity. Out of 12 IHS Areas, 10 had higher case rates for CT, 3 for GC, and 4 for P&S syphilis compared to rates for all races/ethnicities. Eight Areas had higher HIV diagnosis rates than for all AI/AN, but HIV rates for all IHS Areas were lower than national rates for all races/ethnicities. Two IHS Areas ranking highest in rates of CT and GC and four Areas with highest P&S syphilis also had high HIV rates. STD and HIV rates among AI/AN were greater in certain IHS Areas than expected from observing national rates for AI/AN. Integrated surveillance of overlapping trends in STDs and HIV may be useful in guiding prevention efforts for AI/AN populations. JF - Journal of Community Health AU - Walker, Frances J AU - Llata, Eloisa AU - Doshani, Mona AU - Taylor, Melanie M AU - Bertolli, Jeanne AU - Weinstock, Hillard S AU - Hall, HIrene AD - Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA, gge3@cdc.gov Y1 - 2015/06// PY - 2015 DA - Jun 2015 SP - 484 EP - 492 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 40 IS - 3 SN - 0094-5145, 0094-5145 KW - Virology & AIDS Abstracts; Microbiology Abstracts B: Bacteriology KW - Guanylate cyclase KW - Sexually-transmitted diseases KW - Human immunodeficiency virus KW - Treponema pallidum KW - Gonorrhea KW - Syphilis KW - Ethnic groups KW - Races KW - Chlamydia KW - J 02410:Animal Diseases KW - V 22360:AIDS and HIV UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1687668419?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Community+Health&rft.atitle=HIV%2C+Chlamydia%2C+Gonorrhea%2C+and+Primary+and+Secondary+Syphilis+among+American+Indians+and+Alaska+Natives+Within+Indian+Health+Service+Areas+in+the+United+States%2C+2007-2010&rft.au=Walker%2C+Frances+J%3BLlata%2C+Eloisa%3BDoshani%2C+Mona%3BTaylor%2C+Melanie+M%3BBertolli%2C+Jeanne%3BWeinstock%2C+Hillard+S%3BHall%2C+HIrene&rft.aulast=Walker&rft.aufirst=Frances&rft.date=2015-06-01&rft.volume=40&rft.issue=3&rft.spage=484&rft.isbn=&rft.btitle=&rft.title=Journal+of+Community+Health&rft.issn=00945145&rft_id=info:doi/10.1007%2Fs10900-014-9961-4 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-06-01 N1 - Number of references - 44 N1 - Last updated - 2015-11-16 N1 - SubjectsTermNotLitGenreText - Guanylate cyclase; Sexually-transmitted diseases; Gonorrhea; Syphilis; Races; Ethnic groups; Human immunodeficiency virus; Treponema pallidum; Chlamydia DO - http://dx.doi.org/10.1007/s10900-014-9961-4 ER - TY - JOUR T1 - Clinical interventions to reduce secondhand smoke exposure among pregnant women: a systematic review AN - 1808712765; PQ0003431015 AB - ObjectiveTo conduct a systematic review of clinical interventions to reduce secondhand smoke (SHS) exposure among non-smoking pregnant women.Data sourcesWe searched 16 databases for publications from 1990 to January 2013, with no language restrictions.Study selectionPapers were included if they met the following criteria: (1) the study population included non-smoking pregnant women exposed to SHS, (2) the clinical interventions were intended to reduce SHS exposure at home, (3) the study included a control group and (4) outcomes included either reduced SHS exposure of non-smoking pregnant women at home or quit rates among smoking partners during the pregnancy of the woman.Data extractionTwo coders independently reviewed each abstract or full text to identify eligible papers. Two abstractors independently coded papers based on US Preventive Services Task Force criteria for study quality (good, fair, poor), and studies without biochemically-verified outcome measures were considered poor quality.Data synthesisFrom 4670 papers, we identified five studies that met our inclusion criteria: four focused on reducing SHS exposure among non-smoking pregnant women, and one focused on providing cessation support for smoking partners of pregnant women. All were randomised controlled trials, and all reported positive findings. Three studies were judged poor quality because outcome measures were not biochemically-verified, and two were considered fair quality.ConclusionsClinical interventions delivered in prenatal care settings appear to reduce SHS exposure, but study weaknesses limit our ability to draw firm conclusions. More rigorous studies, using biochemical validation, are needed to identify strategies for reducing SHS exposure in pregnant women. JF - Tobacco Control AU - Tong, Van T AU - Dietz, Patricia M AU - Rolle, Italia V AU - Kennedy, Sara M AU - Thomas, William AU - England, Lucinda J AD - Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, , Atlanta, Georgia, USA Y1 - 2015/05/30/ PY - 2015 DA - 2015 May 30 SP - 217 EP - 223 PB - BMJ Publishing Group Ltd. VL - 24 IS - 3 SN - 0964-4563, 0964-4563 KW - Toxicology Abstracts KW - Environmental tobacco smoke KW - secondhand smoke KW - non-smoking pregnant women KW - pregnancy KW - partner cessation KW - clinical interventions KW - Smoke KW - Smoking KW - Databases KW - Prenatal experience KW - Reviews KW - Tobacco KW - Population studies KW - Language KW - Clinical trials KW - Pregnancy KW - X 24380:Social Poisons & Drug Abuse UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808712765?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Tobacco+Control&rft.atitle=Clinical+interventions+to+reduce+secondhand+smoke+exposure+among+pregnant+women%3A+a+systematic+review&rft.au=Tong%2C+Van+T%3BDietz%2C+Patricia+M%3BRolle%2C+Italia+V%3BKennedy%2C+Sara+M%3BThomas%2C+William%3BEngland%2C+Lucinda+J&rft.aulast=Tong&rft.aufirst=Van&rft.date=2015-05-30&rft.volume=24&rft.issue=3&rft.spage=217&rft.isbn=&rft.btitle=&rft.title=Tobacco+Control&rft.issn=09644563&rft_id=info:doi/10.1136%2Ftobaccocontrol-2013-051200 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-09-01 N1 - SubjectsTermNotLitGenreText - Smoke; Databases; Smoking; Prenatal experience; Reviews; Tobacco; Population studies; Language; Clinical trials; Pregnancy DO - http://dx.doi.org/10.1136/tobaccocontrol-2013-051200 ER - TY - CPAPER T1 - Use of Smartphone Sound Measurement Apps for Occupational Noise Assessments T2 - 169th Meeting of the Acoustical Society of America AN - 1669823919; 6341645 JF - 169th Meeting of the Acoustical Society of America AU - Kardous, Chucri AU - Celestina, Metod Y1 - 2015/05/18/ PY - 2015 DA - 2015 May 18 KW - Sound measurement KW - Noise levels UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1669823919?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=169th+Meeting+of+the+Acoustical+Society+of+America&rft.atitle=Use+of+Smartphone+Sound+Measurement+Apps+for+Occupational+Noise+Assessments&rft.au=Dave%2C+Dhaval+M%3BDecker%2C+Sandra+L%3BKaestner%2C+Robert%3BSimon%2C+Kosali+Ilayperuma&rft.aulast=Dave&rft.aufirst=Dhaval&rft.date=2010-01-01&rft.volume=47&rft.issue=4&rft.spage=315&rft.isbn=&rft.btitle=&rft.title=Inquiry+%28Rochester%29&rft.issn=00469580&rft_id=info:doi/10.5034%2Finquiryjrnl_47.04.315 L2 - https://asa2015spring.abstractcentral.com/planner.jsp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-31 N1 - Last updated - 2015-04-06 ER - TY - JOUR T1 - Epidemiology of imported malaria in Quanzhou in 2002-2013 AN - 1776641830; PQ0002740072 AB - Objective To discuss the epidemiological characteristics of imported malaria in Quanzhou from 2002 to 2013. Methods Data of patients with imported malaria were analyzed by SPSS 18.0,and chi-square test was used for statistical analysis. Results A total of 64 cases with imported malaria were reported during a12 year period,including 23 cases of plasmodium falciparum,35 cases of plasmodium vivax and 6unknown type of plasmodium.76.56% of cases were 20 to 49years old,and male to female ratio was 6.11:1.Farmers accounted for 37.50% of total cases,followed by migrant workers(21.88%)and commercial service individuals(10.93%).Plasmodium vivaxand Plasmodium falciparum were predominant among patients with malaria diagnosed in 2002-2008 and in 2010-2013,respectively.Imported malaria cases from mainland and Asia were mainly infected with Plasmodium vivax,while patients from Africa were infected with Plasmodium falciparum,the difference was significant. Conclusions No patient with malaria has been found locally infected during 12 year period in Quanzhou,however,imported cases are reported each year.Therefore,it is critical to strengthen the prevention and control of imported malaria. JF - Zhongguo Yufang Yixue Zazhi - Chinese Preventive Medicine AU - Chen, Hai-yan AD - Quanzhou Center for Disease Control and Prevention Y1 - 2015/05// PY - 2015 DA - May 2015 PB - Zhonghua Yufang Yixuehui VL - 16 IS - 5 SN - 1009-6639, 1009-6639 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Microbiology Abstracts C: Algology, Mycology & Protozoology; Health & Safety Science Abstracts KW - Malaria KW - Imported case KW - Epidemiology KW - Parasites KW - Human diseases KW - Data processing KW - Statistical analysis KW - Plasmodium vivax KW - Plasmodium falciparum KW - Public health KW - Methodology KW - Prevention KW - Africa KW - Asia KW - K 03400:Human Diseases KW - Q1 08604:Stock assessment and management KW - H 12000:Epidemiology and Public Health KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1776641830?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Zhongguo+Yufang+Yixue+Zazhi+-+Chinese+Preventive+Medicine&rft.atitle=Epidemiology+of+imported+malaria+in+Quanzhou+in+2002-2013&rft.au=Chen%2C+Hai-yan&rft.aulast=Chen&rft.aufirst=Hai-yan&rft.date=2015-05-01&rft.volume=16&rft.issue=5&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Zhongguo+Yufang+Yixue+Zazhi+-+Chinese+Preventive+Medicine&rft.issn=10096639&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-03-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Parasites; Human diseases; Epidemiology; Malaria; Methodology; Public health; Data processing; Statistical analysis; Prevention; Plasmodium vivax; Plasmodium falciparum; Africa; Asia ER - TY - JOUR T1 - Tuberculosis and vitamin D: what's the rest of the story? AN - 1773825175; PQ0001709365 JF - Lancet Infectious Diseases AU - Cegielski, Peter AU - Vernon, Andrew AD - Division of Tuberculosis Elimination, The National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, US Centers for Disease Control and Prevention, Atlanta, GA 30329, USA Y1 - 2015/05// PY - 2015 DA - May 2015 SP - 489 EP - 490 PB - Elsevier B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 15 IS - 5 SN - 1473-3099, 1473-3099 KW - Microbiology Abstracts B: Bacteriology KW - Vitamin D KW - Mycobacterium KW - Tuberculosis KW - J 02330:Biochemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1773825175?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Lancet+Infectious+Diseases&rft.atitle=Tuberculosis+and+vitamin+D%3A+what%27s+the+rest+of+the+story%3F&rft.au=Cegielski%2C+Peter%3BVernon%2C+Andrew&rft.aulast=Cegielski&rft.aufirst=Peter&rft.date=2015-05-01&rft.volume=15&rft.issue=5&rft.spage=489&rft.isbn=&rft.btitle=&rft.title=Lancet+Infectious+Diseases&rft.issn=14733099&rft_id=info:doi/10.1016%2FS1473-3099%2815%2970163-5 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-03-01 N1 - Number of references - 14 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Vitamin D; Tuberculosis; Mycobacterium DO - http://dx.doi.org/10.1016/S1473-3099(15)70163-5 ER - TY - JOUR T1 - The Influence of Diet on the Use of Near-Infrared Spectroscopy to Determine the Age of Female Aedes aegypti Mosquitoes AN - 1727684723; PQ0002118770 AB - Interventions targeting adult mosquitoes are used to combat transmission of vector-borne diseases, including dengue. Without available vaccines, targeting the primary vector, Aedes aegypti, is essential to prevent transmission. Older mosquitoes (> or = 7 days) are of greatest epidemiological significance due to the 7-day extrinsic incubation period of the virus. Age-grading of female mosquitoes is necessary to identify post-intervention changes in mosquito population age structure. We developed models using near-infrared spectroscopy (NIRS) to age-grade adult female Ae. aegypti. To determine if diet affects the ability of NIRS models to predict age, two identical larval groups were fed either fish food or Infant cereal. Adult females were separated and fed sugar water + or - blood, resulting in four experimental groups. Females were killed 1, 4, 7, 10, 13, or 16 days postemergence. The head/thorax of each mosquito was scanned using a near-infrared spectrometer. Scans from each group were analyzed, and multiple models were developed using partial least squares regression. The best model included all experimental groups, and positively predicted the age group ( or = 7 days) of 90.2% mosquitoes. These results suggest both larval and adult diets can affect the ability of NIRS models to accurately assign age categories to female Ae. aegypti. JF - American Journal of Tropical Medicine and Hygiene AU - Liebman, Kelly AU - Swamidoss, Isabel AU - Vizcaino, Lucrecia AU - Lenhart, Audrey AU - Dowell, Floyd AU - Wirtz, Robert AD - Centers for Disease Control and Prevention, Atlanta, Georgia, wuq4@cdc.gov Y1 - 2015/05// PY - 2015 DA - May 2015 SP - 1070 EP - 1075 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 92 IS - 5 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Entomology Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Aedes aegypti KW - Age KW - Food KW - Vector-borne diseases KW - Larval development KW - Models KW - Public health KW - Disease transmission KW - Cereals KW - Dengue KW - I.R. spectroscopy KW - Regression analysis KW - Thorax KW - Aquatic insects KW - Diets KW - Sugar KW - Age composition KW - I.R. radiation KW - Head KW - Vectors KW - Age determination KW - Blood KW - Feeding experiments KW - Vaccines KW - Hygiene KW - Infants KW - K 03400:Human Diseases KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - J 02400:Human Diseases KW - Q1 08485:Species interactions: pests and control KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727684723?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=The+Influence+of+Diet+on+the+Use+of+Near-Infrared+Spectroscopy+to+Determine+the+Age+of+Female+Aedes+aegypti+Mosquitoes&rft.au=Liebman%2C+Kelly%3BSwamidoss%2C+Isabel%3BVizcaino%2C+Lucrecia%3BLenhart%2C+Audrey%3BDowell%2C+Floyd%3BWirtz%2C+Robert&rft.aulast=Liebman&rft.aufirst=Kelly&rft.date=2015-05-01&rft.volume=92&rft.issue=5&rft.spage=1070&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0790 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Diets; Feeding experiments; Vaccines; Age determination; Hygiene; Larval development; Aquatic insects; Disease transmission; Public health; Sugar; Age composition; Age; I.R. radiation; Head; Food; Vector-borne diseases; Vectors; Models; Blood; Cereals; I.R. spectroscopy; Dengue; Thorax; Regression analysis; Infants; Aedes aegypti DO - http://dx.doi.org/10.4269/ajtmh.14-0790 ER - TY - JOUR T1 - Meteorological Conditions Associated with Increased Incidence of West Nile Virus Disease in the United States, 2004-2012 AN - 1727684409; PQ0002118762 AB - West Nile virus (WNV) is a leading cause of mosquito-borne disease in the United States. Annual seasonal outbreaks vary in size and location. Predicting where and when higher than normal WNV transmission will occur can help direct limited public health resources. We developed models for the contiguous United States to identify meteorological anomalies associated with above average incidence of WNV neuroinvasive disease from 2004 to 2012. We used county-level WNV data reported to ArboNET and meteorological data from the North American Land Data Assimilation System. As a result of geographic differences in WNV transmission, we divided the United States into East and West, and 10 climate regions. Above average annual temperature was associated with increased likelihood of higher than normal WNV disease incidence, nationally and in most regions. Lower than average annual total precipitation was associated with higher disease incidence in the eastern United States, but the opposite was true in most western regions. Although multiple factors influence WNV transmission, these findings show that anomalies in temperature and precipitation are associated with above average WNV disease incidence. Readily accessible meteorological data may be used to develop predictive models to forecast geographic areas with elevated WNV disease risk before the coming season. JF - American Journal of Tropical Medicine and Hygiene AU - Hahn, Micah B AU - Monaghan, Andrew J AU - Hayden, Mary H AU - Eisen, Rebecca J AU - Delorey, Mark J AU - Lindsey, Nicole P AU - Nasci, Roger S AU - Fischer, Marc AD - National Center for Atmospheric Research, Boulder, Colorado, mfischer@cdc.gov Y1 - 2015/05// PY - 2015 DA - May 2015 SP - 1013 EP - 1022 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 92 IS - 5 SN - 0002-9637, 0002-9637 KW - Meteorological & Geoastrophysical Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Prediction KW - Temperature effects KW - Meteorological data KW - Invasiveness KW - Data processing KW - Climate KW - Precipitation KW - Data assimilation KW - Disease transmission KW - Public health KW - USA KW - Seasonal variability KW - Hygiene KW - Meteorological conditions KW - Aquatic insects KW - West Nile virus KW - K 03410:Animal Diseases KW - J 02400:Human Diseases KW - Q1 08604:Stock assessment and management KW - Q5 08524:Public health, medicines, dangerous organisms KW - M2 551.509.1/.5:Forecasting (551.509.1/.5) KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727684409?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Meteorological+Conditions+Associated+with+Increased+Incidence+of+West+Nile+Virus+Disease+in+the+United+States%2C+2004-2012&rft.au=Hahn%2C+Micah+B%3BMonaghan%2C+Andrew+J%3BHayden%2C+Mary+H%3BEisen%2C+Rebecca+J%3BDelorey%2C+Mark+J%3BLindsey%2C+Nicole+P%3BNasci%2C+Roger+S%3BFischer%2C+Marc&rft.aulast=Hahn&rft.aufirst=Micah&rft.date=2015-05-01&rft.volume=92&rft.issue=5&rft.spage=1013&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0737 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Temperature effects; Prediction; Meteorological data; Climate; Hygiene; Aquatic insects; Public health; Disease transmission; Invasiveness; Data processing; Seasonal variability; Precipitation; Data assimilation; Meteorological conditions; West Nile virus; USA DO - http://dx.doi.org/10.4269/ajtmh.14-0737 ER - TY - JOUR T1 - Comparison of Antimicrobial Susceptibilities of Pharyngeal, Rectal, and Urethral Neisseria gonorrhoeae Isolates among Men Who Have Sex with Men AN - 1683352524; PQ0001539696 AB - U.S. surveillance for Neisseria gonorrhoeae antimicrobial susceptibilities is based exclusively on male urethral isolates. These data inform gonorrhea treatment guidelines, including recommendations for the treatment of extragenital infections, but data on the susceptibilities of extragenital isolates are limited. We compared the antimicrobial susceptibilities of pharyngeal, rectal, and urethral gonococcal isolates collected from men who have sex with men (MSM), at five sentinel sites throughout the United States. MICs were determined by the agar dilution method. Generalized linear models were used to compare (i) the proportions of isolates with elevated MICs and (ii) geometric mean MICs according to anatomic site, adjusted for city. In December 2011 to September 2013, totals of 205 pharyngeal, 261 rectal, and 976 urethral isolates were obtained. The proportions of isolates with elevated ceftriaxone MICs ( greater than or equal to 0.125 mu g/ml) did not differ according to anatomic site (0.5% of pharyngeal isolates, 1.5% of rectal isolates, and 1.7% of urethral isolates, with a city-adjusted odds ratio [aOR] of 0.4 [95% confidence interval {CI}, 0.0 to 3.9] for pharyngeal versus urethral isolates and an aOR of 0.9 [95% CI, 0.2 to 4.2] for rectal versus urethral isolates). The city-adjusted geometric mean ceftriaxone MICs of pharyngeal (0.0153 mu g/ml) and rectal (0.0157 mu g/ml) isolates did not differ from that of urethral isolates (0.0150 mu g/ml) (ratios of geometric mean MICs of 1.02 [95% CI, 0.90 to 1.17] and 1.05 [95% CI, 0.93 to 1.19], respectively). Similar results were observed for other antimicrobials, including cefixime and azithromycin. These findings suggest that, at the population level, gonococcal antimicrobial susceptibility surveillance based on urethral isolates from MSM adequately reflects the susceptibilities of N. gonorrhoeae strains circulating among MSM. JF - Antimicrobial Agents & Chemotherapy AU - Kidd, Sarah AU - Zaidi, Akbar AU - Asbel, Lenore AU - Baldwin, Tamara AU - Gratzer, Beau AU - Guerry, Sarah AU - Kerani, Roxanne P AU - Pathela, Preeti AU - Pettus, Kevin AU - Soge, Olusegun O AD - Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, skidd@cdc.gov. Y1 - 2015/05// PY - 2015 DA - May 2015 SP - 2588 EP - 2595 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 59 IS - 5 SN - 0066-4804, 0066-4804 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Agar KW - Data processing KW - Pharynx KW - Rectum KW - Ceftriaxone KW - Infection KW - Minimum inhibitory concentration KW - Neisseria gonorrhoeae KW - Models KW - Antimicrobial agents KW - Azithromycin KW - Cefixime KW - Gonorrhea KW - Population levels KW - Sex KW - A 01340:Antibiotics & Antimicrobials KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1683352524?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Comparison+of+Antimicrobial+Susceptibilities+of+Pharyngeal%2C+Rectal%2C+and+Urethral+Neisseria+gonorrhoeae+Isolates+among+Men+Who+Have+Sex+with+Men&rft.au=Kidd%2C+Sarah%3BZaidi%2C+Akbar%3BAsbel%2C+Lenore%3BBaldwin%2C+Tamara%3BGratzer%2C+Beau%3BGuerry%2C+Sarah%3BKerani%2C+Roxanne+P%3BPathela%2C+Preeti%3BPettus%2C+Kevin%3BSoge%2C+Olusegun+O&rft.aulast=Kidd&rft.aufirst=Sarah&rft.date=2015-05-01&rft.volume=59&rft.issue=5&rft.spage=2588&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.04476-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-05-01 N1 - Number of references - 38 N1 - Last updated - 2015-11-16 N1 - SubjectsTermNotLitGenreText - Agar; Rectum; Pharynx; Data processing; Ceftriaxone; Infection; Minimum inhibitory concentration; Antimicrobial agents; Models; Azithromycin; Cefixime; Population levels; Gonorrhea; Sex; Neisseria gonorrhoeae DO - http://dx.doi.org/10.1128/AAC.04476-14 ER - TY - JOUR T1 - Neuraminidase Mutations Conferring Resistance to Oseltamivir in Influenza A(H7N9) Viruses AN - 1683350072; PQ0001540013 AB - Human infections by avian influenza A(H7N9) virus entail substantial morbidity and mortality. Treatment of infected patients with the neuraminidase (NA) inhibitor oseltamivir was associated with emergence of viruses carrying NA substitutions. In the NA inhibition (NI) assay, R292K conferred highly reduced inhibition by oseltamivir, while E119V and I222K each caused reduced inhibition. To facilitate establishment of laboratory correlates of clinically relevant resistance, experiments were conducted in ferrets infected with virus carrying wild-type or variant NA genes recovered from the A/Taiwan/1/2013 isolate. Oseltamivir treatment (5 or 25 mg/kg of body weight/dose) was given 4 h postinfection, followed by twice-daily treatment for 5 days. Treatment of ferrets infected with wild-type virus resulted in a modest dose-dependent reduction (0.7 to 1.5 log10 50% tissue culture infectious dose [TCID50]) in nasal wash viral titers and inflammation response. Conversely, treatment failed to significantly inhibit the replication of R292K or E119V virus. A small reduction of viral titers was detected on day 5 in ferrets infected with the I222K virus. The propensity for oseltamivir resistance emergence was assessed in oseltamivir-treated animals infected with wild-type virus; emergence of R292K virus was detected in 3 of 6 ferrets within 5 to 7 days postinfection. Collectively, we demonstrate that R292K, E119V, and I222K reduced the inhibitory activity of oseltamivir, not only in the NI assay, but also in infected ferrets, judged particularly by viral loads in nasal washes, and may signal the need for alternative therapeutics. Thus, these clinical outcomes measured in the ferret model may correlate with clinically relevant oseltamivir resistance in humans. IMPORTANCE This report provides more evidence for using the ferret model to assess the susceptibility of influenza A(H7N9) viruses to oseltamivir, the most prescribed anti-influenza virus drug. The information gained can be used to assist in the establishment of laboratory correlates of human disease and drug therapy. The rapid emergence of viruses with R292K in treated ferrets correlates well with the multiple reports on this NA variant in treated human patients. Our findings highlight the importance of the discovery and characterization of new antiviral drugs with different mechanisms of action and the use of combination treatment strategies against emerging viruses with pandemic potential, such as avian H7N9 virus, particularly against those carrying drug resistance markers. JF - Journal of Virology AU - Marjuki, Henju AU - Mishin, Vasiliy P AU - Chesnokov, Anton P AU - De La Cruz, Juan A AU - Davis, Charles T AU - Villanueva, Julie M AU - Fry, Alicia M AU - Gubareva, Larisa V AD - Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, lgubareva@cdc.gov. Y1 - 2015/05// PY - 2015 DA - May 2015 SP - 5419 EP - 5426 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 89 IS - 10 SN - 0022-538X, 0022-538X KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Drug resistance KW - Viruses KW - Disease resistance KW - Infection KW - Morbidity KW - Models KW - Influenza KW - pandemics KW - Mustela KW - Antiviral agents KW - Body weight KW - Exo- alpha -sialidase KW - Drugs KW - Mortality KW - Laboratory testing KW - Replication KW - Tissue culture KW - Inflammation KW - Oseltamivir KW - Fowl plague KW - ISEW, Taiwan KW - Mutation KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - V 22320:Replication UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1683350072?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Virology&rft.atitle=Neuraminidase+Mutations+Conferring+Resistance+to+Oseltamivir+in+Influenza+A%28H7N9%29+Viruses&rft.au=Marjuki%2C+Henju%3BMishin%2C+Vasiliy+P%3BChesnokov%2C+Anton+P%3BDe+La+Cruz%2C+Juan+A%3BDavis%2C+Charles+T%3BVillanueva%2C+Julie+M%3BFry%2C+Alicia+M%3BGubareva%2C+Larisa+V&rft.aulast=Marjuki&rft.aufirst=Henju&rft.date=2015-05-01&rft.volume=89&rft.issue=10&rft.spage=5419&rft.isbn=&rft.btitle=&rft.title=Journal+of+Virology&rft.issn=0022538X&rft_id=info:doi/10.1128%2FJVI.03513-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-05-01 N1 - Number of references - 40 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Mortality; Replication; Drug resistance; Disease resistance; Tissue culture; Infection; Morbidity; Oseltamivir; Models; Inflammation; Influenza; Fowl plague; pandemics; Body weight; Antiviral agents; Exo- alpha -sialidase; Mutation; Laboratory testing; Viruses; Drugs; Mustela; ISEW, Taiwan DO - http://dx.doi.org/10.1128/JVI.03513-14 ER - TY - JOUR T1 - The impact of adherence to preexposure prophylaxis on the risk of HIV infection among people who inject drugs AN - 1808693039; PQ0003241730 AB - Objective: To describe participant adherence to daily oral tenofovir in an HIV preexposure prophylaxis (PrEP) trial, examine factors associated with adherence, and assess the impact of adherence on the risk of HIV infection. Design: The Bangkok Tenofovir Study was a randomized, double-blind, placebo-controlled trial conducted among people who inject drugs, 2005-2012. Methods: Participants chose daily visits or monthly visits. Study nurses observed participants swallow study drug and both initialed a diary. We assessed adherence using the diary. We examined adherence by age group and sex and used logistic regression to evaluate demographics and risk behaviors as predictors of adherence and Cox regression to assess the impact of adherence on the risk of HIV infection. Results: A total of 2413 people enrolled and contributed 9665 person-years of follow-up (mean 4.0 years, maximum 6.9 years). The risk of HIV infection decreased as adherence improved, from 48.9% overall to 83.5% for those with at least 97.5% adherence. In multivariable analysis, men were less adherent than women (P=0.006) and participants 20-29 years old (P<0.001) and 30-39 years old (P=0.01) were less adherent than older participants. Other factors associated with poor adherence included incarceration (P=0.02) and injecting methamphetamine (P=0.04). Conclusion: In this HIV PrEP trial among people who inject drugs, improved adherence to daily tenofovir was associated with a lower risk of HIV infection. This is consistent with trials among MSM and HIV-discordant heterosexual couples and suggests that HIV PrEP can provide a high level of protection from HIV infection. JF - AIDS AU - Martin, Michael AU - Vanichseni, Suphak AU - Suntharasamai, Pravan AU - Sangkum, Udomsak AU - Mock, Philip A AU - Leethochawalit, Manoj AU - Chiamwongpaet, Sithisat AU - Curlin, Marcel E AU - Na-pompet, Supawadee AU - Warapronmongkholkul, Anchalee AD - Thailand MOPH - US CDC Collaboration, Nonthaburi, Thailand, Znd9@cdc.gov Y1 - 2015/04/24/ PY - 2015 DA - 2015 Apr 24 SP - 819 EP - 824 PB - Lippincott Williams & Wilkins, Inc, 530 Walnut Street Philadelphia PA 19106-3621 United States VL - 29 IS - 7 SN - 0269-9370, 0269-9370 KW - Health & Safety Science Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - adherence KW - HIV KW - people who inject drugs KW - preexposure prophylaxis KW - tenofovir KW - Risk assessment KW - Acquired immune deficiency syndrome KW - Age KW - Risk taking KW - Thailand, Chacoengsao Prov., Bangkok KW - Infection KW - Drug abuse KW - Clinical trials KW - Medical personnel KW - Demography KW - Nursing KW - Risk factors KW - Drugs KW - Sex KW - Drug development KW - Health risks KW - Methamphetamine KW - Human immunodeficiency virus KW - Prophylaxis KW - V 22360:AIDS and HIV KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808693039?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS&rft.atitle=The+impact+of+adherence+to+preexposure+prophylaxis+on+the+risk+of+HIV+infection+among+people+who+inject+drugs&rft.au=Martin%2C+Michael%3BVanichseni%2C+Suphak%3BSuntharasamai%2C+Pravan%3BSangkum%2C+Udomsak%3BMock%2C+Philip+A%3BLeethochawalit%2C+Manoj%3BChiamwongpaet%2C+Sithisat%3BCurlin%2C+Marcel+E%3BNa-pompet%2C+Supawadee%3BWarapronmongkholkul%2C+Anchalee&rft.aulast=Martin&rft.aufirst=Michael&rft.date=2015-04-24&rft.volume=29&rft.issue=7&rft.spage=819&rft.isbn=&rft.btitle=&rft.title=AIDS&rft.issn=02699370&rft_id=info:doi/10.1097%2FQAD.0000000000000613 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-08-04 N1 - SubjectsTermNotLitGenreText - Demography; Age; Methamphetamine; Risk factors; Prophylaxis; Drug development; tenofovir; Drug abuse; Infection; Sex; Risk assessment; Acquired immune deficiency syndrome; Risk taking; Clinical trials; Medical personnel; Health risks; Human immunodeficiency virus; Nursing; Drugs; Thailand, Chacoengsao Prov., Bangkok DO - http://dx.doi.org/10.1097/QAD.0000000000000613 ER - TY - JOUR T1 - Functional characterization of botulinum neurotoxin serotype H as a hybrid of known serotypes F and A (BoNT F/A). AN - 1671217933; 25731972 AB - A unique strain of Clostridium botulinum (IBCA10-7060) was recently discovered which produces two toxins: botulinum neurotoxin (BoNT) serotype B and a novel BoNT reported as serotype H. Previous molecular assessment showed that the light chain (LC) of the novel BoNT most resembled the bont of the light chain of known subtype F5, while the C-terminus of the heavy chain (HC) most resembled the binding domain of serotype A. We evaluated the functionality of both toxins produced in culture by first incorporating an immunoaffinity step using monoclonal antibodies to purify BoNT from culture supernatants and tested each immune-captured neurotoxin with full-length substrates vesicle-associated membrane protein 2 (VAMP-2), synaptosomal-associated protein 25 (SNAP-25), syntaxin, and shortened peptides representing the substrates. The BoNT/B produced by this strain behaved as a typical BoNT/B, having immunoaffinity for anti-B monoclonal antibodies and cleaving both full length VAMP-2 and a peptide based on the sequence of VAMP-2 in the expected location. As expected, there was no activity toward SNAP-25 or syntaxin. The novel BoNT demonstrated immunoaffinity for anti-A monoclonal antibodies but did not cleave SNAP-25 as expected for BoNT/A. Instead, the novel BoNT cleaved VAMP-2 and VAMP-2-based peptides in the same location as BoNT/F5. This is the first discovery of a single botulinum neurotoxin with BoNT/A antigenicity and BoNT/F light chain function. This work suggests that the newly reported serotype H may actually be a hybrid of previously known BoNT serotype A and serotype F, specifically subtype F5. JF - Analytical chemistry AU - Kalb, Suzanne R AU - Baudys, Jakub AU - Raphael, Brian H AU - Dykes, Janet K AU - Lúquez, Carolina AU - Maslanka, Susan E AU - Barr, John R AD - †Centers for Disease Control and Prevention, National Center for Environmental Health, Division of Laboratory Sciences, 4770 Buford Hwy NE, Atlanta, Georgia 30341, United States. ; ‡Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases, Enteric Diseases Laboratory Branch, 1600 Clifton Road, Atlanta, Georgia 30329, United States. Y1 - 2015/04/07/ PY - 2015 DA - 2015 Apr 07 SP - 3911 EP - 3917 VL - 87 IS - 7 KW - botulinum toxin type F KW - 0 KW - Botulinum Toxins KW - EC 3.4.24.69 KW - Botulinum Toxins, Type A KW - Index Medicus KW - Mass Spectrometry KW - Chromatography, Liquid KW - Botulinum Toxins, Type A -- metabolism KW - Clostridium botulinum -- metabolism KW - Botulinum Toxins -- chemistry KW - Botulinum Toxins -- metabolism KW - Clostridium botulinum -- chemistry KW - Botulinum Toxins, Type A -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1671217933?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytical+chemistry&rft.atitle=Functional+characterization+of+botulinum+neurotoxin+serotype+H+as+a+hybrid+of+known+serotypes+F+and+A+%28BoNT+F%2FA%29.&rft.au=Kalb%2C+Suzanne+R%3BBaudys%2C+Jakub%3BRaphael%2C+Brian+H%3BDykes%2C+Janet+K%3BL%C3%BAquez%2C+Carolina%3BMaslanka%2C+Susan+E%3BBarr%2C+John+R&rft.aulast=Kalb&rft.aufirst=Suzanne&rft.date=2015-04-07&rft.volume=87&rft.issue=7&rft.spage=3911&rft.isbn=&rft.btitle=&rft.title=Analytical+chemistry&rft.issn=1520-6882&rft_id=info:doi/10.1021%2Fac504716v LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2015-10-09 N1 - Date created - 2015-04-07 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Cited By: Emerg Infect Dis. 2005 Oct;11(10):1578-83 [16318699] Biochim Biophys Acta. 1996 Jun 7;1307(2):123-6 [8679691] J Biol Chem. 1996 Mar 29;271(13):7694-9 [8631808] Biochemistry. 1996 Feb 27;35(8):2630-6 [8611567] J Biol Chem. 1995 May 5;270(18):10566-70 [7737992] J Biol Chem. 1994 Aug 12;269(32):20213-6 [8051110] Biochem Biophys Res Commun. 1994 Apr 29;200(2):829-35 [7910017] J Biol Chem. 1994 Apr 29;269(17):12764-72 [8175689] J Biol Chem. 1994 Jan 21;269(3):1617-20 [8294407] FEBS Lett. 1993 Nov 29;335(1):99-103 [8243676] J Biol Chem. 1993 Nov 15;268(32):23784-7 [8226912] EMBO J. 1993 Dec;12(12):4821-8 [7901002] Nature. 1993 Sep 9;365(6442):160-3 [8103915] J Biol Chem. 1993 Jun 5;268(16):11516-9 [8505288] Nature. 1992 Oct 29;359(6398):832-5 [1331807] Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11346-50 [12177434] Anal Chem. 2014 Apr 1;86(7):3254-62 [24605815] J Infect Dis. 2014 Jan 15;209(2):183-91 [24106296] FEBS Lett. 2012 Jan 20;586(2):109-15 [22172278] FEMS Immunol Med Microbiol. 2011 Apr;61(3):288-300 [21205003] Appl Environ Microbiol. 2011 Feb;77(4):1301-8 [21169446] Appl Environ Microbiol. 2010 Jul;76(14):4805-12 [20511432] Nat Biotechnol. 2007 Jan;25(1):107-16 [17173035] J Bacteriol. 2007 Feb;189(3):818-32 [17114256] PLoS One. 2009;4(4):e5355 [19399171] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1021/ac504716v ER - TY - JOUR T1 - The composition of intestinal microbiota in women with perimenopausal syndrome AN - 1805508825; PQ0002897606 AB - Objective To detect qualitatively and quantitatively the intestinal microbiota in women with perimenopausal syntrome in order to learn the microecological status and characteristics of the intestinal microbiota and provide data for researches on novel ways of treating and preventing perimenopausal syndrome. Methods An experimental group including women with perimenopausal syndrome and a control group including similar-aged healthy female volunteers were set. Mitsuoka method was used for detection of intestinal microbiota,including Bifidobcteria,Lactobacilli,Bacteriodes,C. perfringens,Peptostreptococci,Enterobacteriaceae,Enterococci and Yeasts,and the ratio of Bifidobcteria to Enterobacteriaceae( B/E ratio) was calculated. Results Compared with the control group,the number of Bifidobcteria in subjects with perimenopausal syndrome markedly reduced( P < 0. 01) and the B/E ratio was also significantly lower( P < 0. 01),while the numbers of Enterobacteriaceae,Enterococci and Peptostreptococci significantly increased( P < 0. 01,P < 0. 01,P < 0. 05 respectively). Conclusion The composition of intesninal microbiota in women with perimenopausal syndrome significantly changed,with the number of Bifidobcteria markedly declining while Enterobacteriaceae and Peptostreptococci increasing; the reason might be the intestinal microbiota dysbiosis resulted from neuroendocrine disorders in women with perimenopausal syndrome. JF - Chinese Journal of Microecology AU - Guo, Zai-qing AD - Center for Disease Control of Huangmei County Y1 - 2015/04// PY - 2015 DA - April 2015 SP - 477 EP - 479 PB - Editorial Department of Chinese Journal of Microecology, 465 Zhongshan Road Dalian 116027 China VL - 27 IS - 4 SN - 1005-376X, 1005-376X KW - Microbiology Abstracts A: Industrial & Applied Microbiology KW - Microbiota KW - Perimenoparsal syndrome KW - Bifidobacteria KW - Enterobacteriaceae KW - Dysbiosis KW - Intestinal microflora KW - Data processing KW - Intestine KW - A 01300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1805508825?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chinese+Journal+of+Microecology&rft.atitle=The+composition+of+intestinal+microbiota+in+women+with+perimenopausal+syndrome&rft.au=Guo%2C+Zai-qing&rft.aulast=Guo&rft.aufirst=Zai-qing&rft.date=2015-04-01&rft.volume=27&rft.issue=4&rft.spage=477&rft.isbn=&rft.btitle=&rft.title=Chinese+Journal+of+Microecology&rft.issn=1005376X&rft_id=info:doi/ LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-08-17 N1 - SubjectsTermNotLitGenreText - Intestinal microflora; Data processing; Intestine; Enterobacteriaceae ER - TY - JOUR T1 - High-sensitivity MALDI-TOF MS quantification of anthrax lethal toxin for diagnostics and evaluation of medical countermeasures AN - 1680448256; PQ0001483290 AB - Inhalation anthrax has a rapid progression and high fatality rate. Pathology and death from inhalation of Bacillus anthracis spores are attributed to the actions of secreted protein toxins. Protective antigen (PA) binds and imports the catalytic component lethal factor (LF), a zinc endoprotease, and edema factor (EF), an adenylyl cyclase, into susceptible cells. PA-LF is termed lethal toxin (LTx) and PA-EF, edema toxin. As the universal transporter for both toxins, PA is an important target for vaccination and immunotherapeutic intervention. However, its quantification has been limited to methods of relatively low analytic sensitivity. Quantification of LTx may be more clinically relevant than LF or PA alone because LTx is the toxic form that acts on cells. A method was developed for LTx-specific quantification in plasma using anti-PA IgG magnetic immunoprecipitation of PA and quantification of LF activity that co-purified with PA. The method was fast (<4 h total time to detection), sensitive at 0.033 ng/mL LTx in plasma for the fast analysis (0.0075 ng/mL LTx in plasma for an 18 h reaction), precise (6.3-9.9 % coefficient of variation), and accurate (0.1-12.7 %error; n greater than or equal to 25). Diagnostic sensitivity was 100 % (n=27 animal/clinical cases). Diagnostic specificity was 100 % (n=141). LTx was detected post-antibiotic treatment in 6/6 treated rhesus macaques and 3/3 clinical cases of inhalation anthrax and as long as 8 days post-treatment. Over the course of infection in two rhesus macaques, LTx was first detected at 0.101 and 0.237 ng/mL at 36 h post-exposure and increased to 1147 and 12,107 ng/mL in late-stage anthrax. This demonstrated the importance of LTx as a diagnostic and therapeutic target. This method provides a sensitive, accurate tool for anthrax toxin detection and evaluation of PA-directed therapeutics. [Figure not available: see fulltext.] JF - Analytical and Bioanalytical Chemistry AU - Boyer, Anne E AU - Gallegos-Candela, Maribel AU - Quinn, Conrad P AU - Woolfitt, Adrian R AU - Brumlow, Judith O AU - Isbell, Katherine AU - Hoffmaster, Alex R AU - Lins, Renato C AU - Barr, John R AD - Centers for Disease Control and Prevention, Atlanta, GA, 30341, USA, jbarr@cdc.gov PY - 2015 SP - 2847 EP - 2858 PB - Springer Science+Business Media, Berlin/Heidelberg Germany VL - 407 IS - 10 SN - 1618-2642, 1618-2642 KW - Aqualine Abstracts; Water Resources Abstracts; Toxicology Abstracts KW - Inhalation KW - Import KW - Pathology KW - Lethal factor KW - Edema KW - Bacillus anthracis KW - Infection KW - Evaluation KW - Bacteria (bacillaceae) (bacillus) KW - Zinc KW - Anthrax KW - Macaca mulatta KW - Adenylate cyclase KW - Anthrax lethal toxin KW - protective antigen KW - Immunoprecipitation KW - Vaccination KW - Toxins KW - Immunoglobulin G KW - Proteins KW - Spores KW - AQ 00001:Water Resources and Supplies KW - X 24390:Radioactive Materials KW - SW 5080:Evaluation, processing and publication UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1680448256?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytical+and+Bioanalytical+Chemistry&rft.atitle=High-sensitivity+MALDI-TOF+MS+quantification+of+anthrax+lethal+toxin+for+diagnostics+and+evaluation+of+medical+countermeasures&rft.au=Boyer%2C+Anne+E%3BGallegos-Candela%2C+Maribel%3BQuinn%2C+Conrad+P%3BWoolfitt%2C+Adrian+R%3BBrumlow%2C+Judith+O%3BIsbell%2C+Katherine%3BHoffmaster%2C+Alex+R%3BLins%2C+Renato+C%3BBarr%2C+John+R&rft.aulast=Boyer&rft.aufirst=Anne&rft.date=2015-04-01&rft.volume=407&rft.issue=10&rft.spage=2847&rft.isbn=&rft.btitle=&rft.title=Analytical+and+Bioanalytical+Chemistry&rft.issn=16182642&rft_id=info:doi/10.1007%2Fs00216-015-8509-5 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-05-01 N1 - Number of references - 36 N1 - Last updated - 2016-01-21 N1 - SubjectsTermNotLitGenreText - Inhalation; Anthrax lethal toxin; Lethal factor; protective antigen; Immunoprecipitation; Edema; Infection; Vaccination; Toxins; Zinc; Immunoglobulin G; Anthrax; Spores; Adenylate cyclase; Evaluation; Import; Pathology; Bacteria (bacillaceae) (bacillus); Proteins; Macaca mulatta; Bacillus anthracis DO - http://dx.doi.org/10.1007/s00216-015-8509-5 ER - TY - JOUR T1 - Structure and Receptor Binding Preferences of Recombinant Hemagglutinins from Avian and Human H6 and H10 Influenza A Virus Subtypes AN - 1676354592; PQ0001421939 AB - During 2013, three new avian influenza A virus subtypes, A(H7N9), A(H6N1), and A(H10N8), resulted in human infections. While the A(H7N9) virus resulted in a significant epidemic in China across 19 provinces and municipalities, both A(H6N1) and A(H10N8) viruses resulted in only a few human infections. This study focuses on the major surface glycoprotein hemagglutinins from both of these novel human viruses. The detailed structural and glycan microarray analyses presented here highlight the idea that both A(H6N1) and A(H10N8) virus hemagglutinins retain a strong avian receptor binding preference and thus currently pose a low risk for sustained human infections. IMPORTANCE Human infections with zoonotic influenza virus subtypes continue to be a great public health concern. We report detailed structural analysis and glycan microarray data for recombinant hemagglutinins from A(H6N1) and A(H10N8) viruses, isolated from human infections in 2013, and compare them with hemagglutinins of avian origin. This is the first structural report of an H6 hemagglutinin, and our results should further the understanding of these viruses and provide useful information to aid in the continuous surveillance of these zoonotic influenza viruses. JF - Journal of Virology AU - Yang, Hua AU - Carney, Paul J AU - Chang, Jessie C AU - Villanueva, Julie M AU - Stevens, James Y1 - 2015/04// PY - 2015 DA - April 2015 SP - 4612 EP - 4623 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 89 IS - 8 SN - 0022-538X, 0022-538X KW - Genetics Abstracts; Risk Abstracts; Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Data processing KW - Epidemics KW - Hemagglutinins KW - Viruses KW - Structural analysis KW - Infection KW - Polysaccharides KW - Public health KW - Influenza KW - Fowl plague KW - Influenza A virus KW - Risk factors KW - China, People's Rep. KW - Glycoproteins KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - G 07880:Human Genetics KW - R2 23060:Medical and environmental health KW - V 22310:Genetics, Taxonomy & Structure UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1676354592?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Virology&rft.atitle=Structure+and+Receptor+Binding+Preferences+of+Recombinant+Hemagglutinins+from+Avian+and+Human+H6+and+H10+Influenza+A+Virus+Subtypes&rft.au=Yang%2C+Hua%3BCarney%2C+Paul+J%3BChang%2C+Jessie+C%3BVillanueva%2C+Julie+M%3BStevens%2C+James&rft.aulast=Yang&rft.aufirst=Hua&rft.date=2015-04-01&rft.volume=89&rft.issue=8&rft.spage=4612&rft.isbn=&rft.btitle=&rft.title=Journal+of+Virology&rft.issn=0022538X&rft_id=info:doi/10.1128%2FJVI.03456-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-04-01 N1 - Number of references - 71 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Fowl plague; Epidemics; Data processing; Risk factors; Hemagglutinins; Glycoproteins; Polysaccharides; Infection; Public health; Influenza; Structural analysis; Viruses; Influenza A virus; China, People's Rep. DO - http://dx.doi.org/10.1128/JVI.03456-14 ER - TY - JOUR T1 - In Vitro Assessment of Dual Drug Combinations To Inhibit Growth of Neisseria gonorrhoeae AN - 1676353534; PQ0001421523 AB - The development of resistance to first-line antimicrobial therapies has led to recommendations for combination therapies for the treatment of gonorrhea infection. Recent studies have shown the success of combination therapies in treating patients, but few have reported on the in vitro activities of these drug combinations. An in vitro assessment of azithromycin in combination with gentamicin demonstrated inhibition of growth and suggests that clinical trials may be warranted to assess the utility of this combination in treating gonorrhea infections. JF - Antimicrobial Agents & Chemotherapy AU - Pettus, Kevin AU - Sharpe, Samera AU - Papp, John R Y1 - 2015/04// PY - 2015 DA - Apr 2015 SP - 2443 EP - 2445 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 59 IS - 4 SN - 0066-4804, 0066-4804 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Gentamicin KW - Azithromycin KW - Gonorrhea KW - Infection KW - Drug screening KW - Clinical trials KW - Neisseria gonorrhoeae KW - Antimicrobial agents KW - A 01340:Antibiotics & Antimicrobials KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1676353534?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=In+Vitro+Assessment+of+Dual+Drug+Combinations+To+Inhibit+Growth+of+Neisseria+gonorrhoeae&rft.au=Pettus%2C+Kevin%3BSharpe%2C+Samera%3BPapp%2C+John+R&rft.aulast=Pettus&rft.aufirst=Kevin&rft.date=2015-04-01&rft.volume=59&rft.issue=4&rft.spage=2443&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.04127-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-04-01 N1 - Number of references - 8 N1 - Last updated - 2015-11-16 N1 - SubjectsTermNotLitGenreText - Gentamicin; Azithromycin; Gonorrhea; Drug screening; Infection; Clinical trials; Antimicrobial agents; Neisseria gonorrhoeae DO - http://dx.doi.org/10.1128/AAC.04127-14 ER - TY - JOUR T1 - Variola Virus-Specific Diagnostic Assays: Characterization, Sensitivity, and Specificity AN - 1676352238; PQ0001421846 AB - A public health response relies upon rapid and reliable confirmation of disease by diagnostic assays. Here, we detail the design and validation of two variola virus-specific real-time PCR assays, since previous assays cross-reacted with newly identified cowpox viruses. The assay specificity must continually be reassessed as other closely related viruses are identified. JF - Journal of Clinical Microbiology AU - Kondas, Ashley V AU - Olson, Victoria A AU - Li, Yu AU - Abel, Jason AU - Laker, Miriam AU - Rose, Laura AU - Wilkins, Kimberly AU - Turner, Jonathan AU - Kline, Richard AU - Damon, Inger K Y1 - 2015/04// PY - 2015 DA - April 2015 SP - 1406 EP - 1410 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 53 IS - 4 SN - 0095-1137, 0095-1137 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Smallpox KW - Sensitivity KW - Viruses KW - Variola KW - Assays KW - Polymerase chain reaction KW - Cowpox KW - Public health KW - H 12000:Epidemiology and Public Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1676352238?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Variola+Virus-Specific+Diagnostic+Assays%3A+Characterization%2C+Sensitivity%2C+and+Specificity&rft.au=Kondas%2C+Ashley+V%3BOlson%2C+Victoria+A%3BLi%2C+Yu%3BAbel%2C+Jason%3BLaker%2C+Miriam%3BRose%2C+Laura%3BWilkins%2C+Kimberly%3BTurner%2C+Jonathan%3BKline%2C+Richard%3BDamon%2C+Inger+K&rft.aulast=Kondas&rft.aufirst=Ashley&rft.date=2015-04-01&rft.volume=53&rft.issue=4&rft.spage=1406&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.03613-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-04-01 N1 - Number of references - 13 N1 - Last updated - 2016-07-20 N1 - SubjectsTermNotLitGenreText - Smallpox; Polymerase chain reaction; Cowpox; Public health; Sensitivity; Viruses; Assays; Variola DO - http://dx.doi.org/10.1128/JCM.03613-14 ER - TY - JOUR T1 - Application of a Seven-Target Pyrosequencing Assay To Improve the Detection of Neuraminidase Inhibitor-Resistant Influenza A(H3N2) Viruses AN - 1676347835; PQ0001421581 AB - National U.S. influenza antiviral surveillance incorporates data generated by neuraminidase (NA) inhibition (NI) testing of isolates supplemented with NA sequence analysis and pyrosequencing analysis of clinical specimens. A lack of established correlates for clinically relevant resistance to NA inhibitors (NAIs) hinders interpretation of NI assay data. Nonetheless, A(H3N2) viruses are commonly monitored for moderately or highly reduced inhibition in the NI assay and/or for the presence of NA markers E119V, R292K, and N294S. In 2012 to 2013, three drug-resistant A(H3N2) viruses were detected by NI assay among isolates (n = 1,424); all showed highly reduced inhibition by oseltamivir and had E119V. In addition, one R292K variant was detected among clinical samples (n = 1,024) by a 3-target pyrosequencing assay. Overall, the frequency of NAI resistance was low (0.16% [4 of 2,448]). To screen for additional NA markers previously identified in viruses from NAI-treated patients, the pyrosequencing assay was modified to include Q136K, I222V, and deletions encompassing residues 245 to 248 (del245-248) and residues 247 to 250 (del247-250). The 7-target pyrosequencing assay detected NA variants carrying E119V, Q136, and del245-248 in an isolate from an oseltamivir-treated patient. Next, this assay was applied to clinical specimens collected from hospitalized patients and submitted for NI testing but failed cell culture propagation. Of the 27 clinical specimens tested, 4 (15%) contained NA changes: R292K (n = 2), E119V (n = 1), and del247-250 (n = 1). Recombinant NAs with del247-250 or del245-248 conferred highly reduced inhibition by oseltamivir, reduced inhibition by zanamivir, and normal inhibition by peramivir and laninamivir. Our results demonstrated the benefits of the 7-target pyrosequencing assay in conducting A(H3N2) antiviral surveillance and testing for clinical care. JF - Antimicrobial Agents & Chemotherapy AU - Tamura, Daisuke AU - Okomo-Adhiambo, Margaret AU - Mishin, Vasiliy P AU - Guo, Zhu AU - Xu, Xiyan AU - Villanueva, Julie AU - Fry, Alicia M AU - Stevens, James AU - Gubareva, Larisa V AD - Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, lqg3@cdc.gov. Y1 - 2015/04// PY - 2015 DA - Apr 2015 SP - 2374 EP - 2379 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 59 IS - 4 SN - 0066-4804, 0066-4804 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Data processing KW - Residues KW - Chemotherapy KW - Drug resistance KW - Viruses KW - Assays KW - Cell culture KW - Zanamivir KW - Antimicrobial agents KW - Oseltamivir KW - Influenza KW - Exo- alpha -sialidase KW - Hospitals KW - A 01340:Antibiotics & Antimicrobials KW - H 13000:Medical Safety KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1676347835?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Application+of+a+Seven-Target+Pyrosequencing+Assay+To+Improve+the+Detection+of+Neuraminidase+Inhibitor-Resistant+Influenza+A%28H3N2%29+Viruses&rft.au=Tamura%2C+Daisuke%3BOkomo-Adhiambo%2C+Margaret%3BMishin%2C+Vasiliy+P%3BGuo%2C+Zhu%3BXu%2C+Xiyan%3BVillanueva%2C+Julie%3BFry%2C+Alicia+M%3BStevens%2C+James%3BGubareva%2C+Larisa+V&rft.aulast=Tamura&rft.aufirst=Daisuke&rft.date=2015-04-01&rft.volume=59&rft.issue=4&rft.spage=2374&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.04939-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-04-01 N1 - Number of references - 30 N1 - Last updated - 2015-09-30 N1 - SubjectsTermNotLitGenreText - Influenza; Data processing; Drug resistance; Cell culture; Exo- alpha -sialidase; Zanamivir; Oseltamivir; Residues; Chemotherapy; Viruses; Assays; Hospitals; Antimicrobial agents DO - http://dx.doi.org/10.1128/AAC.04939-14 ER - TY - JOUR T1 - A(H7N9) Virus Results in Early Induction of Proinflammatory Cytokine Responses in both Human Lung Epithelial and Endothelial Cells and Shows Increased Human Adaptation Compared with Avian H5N1 Virus AN - 1676346024; PQ0001421927 AB - Similar to H5N1 viruses, A(H7N9) influenza viruses have been associated with severe respiratory disease and fatal outcomes in humans. While high viral load, hypercytokinemia, and pulmonary endothelial cell involvement are known to be hallmarks of H5N1 virus infection, the pathogenic mechanism of the A(H7N9) virus in humans is largely unknown. In this study, we assessed the ability of A(H7N9) virus to infect, replicate, and elicit innate immune responses in both human bronchial epithelial cells and pulmonary microvascular endothelial cells, compared with the abilities of seasonal H3N2, avian H7N9, and H5N1 viruses. In epithelial cells, A(H7N9) virus replicated efficiently but did not elicit robust induction of cytokines like that observed for H5N1 virus. In pulmonary endothelial cells, A(H7N9) virus efficiently initiated infection; however, no released infectious virus was detected. The magnitudes of induction of host cytokine responses were comparable between A(H7N9) and H5N1 virus infection. Additionally, we utilized differentiated human primary bronchial and tracheal epithelial cells to investigate cellular tropism using transmission electron microscopy and the impact of temperature on virus replication. Interestingly, A(H7N9) virus budded from the surfaces of both ciliated and mucin-secretory cells. Furthermore, A(H7N9) virus replicated to a significantly higher titer at 37 degree C than at 33 degree C, with improved replication capacity at 33 degree C compared to that of H5N1 virus. These findings suggest that a high viral load from lung epithelial cells coupled with induction of host responses in endothelial cells may contribute to the severe pulmonary disease observed following H7N9 virus infection. Improved adaptation of A(H7N9) virus to human upper airway poses an important threat to public health. IMPORTANCE A(H7N9) influenza viruses have caused over 450 documented human infections with a 30% fatality rate since early 2013. However, these novel viruses lack many molecular determinants previously identified with mammalian pathogenicity, necessitating a closer examination of how these viruses elicit host responses which could be detrimental. This study provides greater insight into the interaction of this virus with host lung epithelial cells and endothelial cells, which results in high viral load, epithelial cell death, and elevated immune response in the lungs, revealing the mechanism of pathogenesis and disease development among A(H7N9)-infected patients. In particular, we characterized the involvement of pulmonary endothelial cells, a cell type in the human lung accessible to influenza virus following damage of the epithelial monolayer, and its potential role in the development of severe pneumonia caused by A(H7N9) infection in humans. JF - Journal of Virology AU - Zeng, Hui AU - Belser, Jessica A AU - Goldsmith, Cynthia S AU - Gustin, Kortney M AU - Veguilla, Vic AU - Katz, Jacqueline M AU - Tumpey, Terrence M AD - Immunology and Pathogenesis Branch, Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, tft9@cdc.gov. Y1 - 2015/04// PY - 2015 DA - April 2015 SP - 4655 EP - 4667 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 89 IS - 8 SN - 0022-538X, 0022-538X KW - Health & Safety Science Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - Epithelial cells KW - Transmission electron microscopy KW - Viruses KW - Respiratory diseases KW - Infection KW - Public health KW - Influenza KW - Endothelial cells KW - Sulfur dioxide KW - Pathogenicity KW - Cytokines KW - Seasonal variations KW - Respiratory tract KW - Temperature effects KW - Mortality KW - Microvasculature KW - Adaptations KW - Replication KW - Tropism KW - Temperature KW - Lung diseases KW - Inflammation KW - Adaptability KW - Influenza virus KW - Lung KW - Microscopy KW - Immune response KW - Pneumonia KW - V 22350:Immunology KW - H 1000:Occupational Safety and Health KW - F 06910:Microorganisms & Parasites UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1676346024?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Virology&rft.atitle=A%28H7N9%29+Virus+Results+in+Early+Induction+of+Proinflammatory+Cytokine+Responses+in+both+Human+Lung+Epithelial+and+Endothelial+Cells+and+Shows+Increased+Human+Adaptation+Compared+with+Avian+H5N1+Virus&rft.au=Zeng%2C+Hui%3BBelser%2C+Jessica+A%3BGoldsmith%2C+Cynthia+S%3BGustin%2C+Kortney+M%3BVeguilla%2C+Vic%3BKatz%2C+Jacqueline+M%3BTumpey%2C+Terrence+M&rft.aulast=Zeng&rft.aufirst=Hui&rft.date=2015-04-01&rft.volume=89&rft.issue=8&rft.spage=4655&rft.isbn=&rft.btitle=&rft.title=Journal+of+Virology&rft.issn=0022538X&rft_id=info:doi/10.1128%2FJVI.03095-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-04-01 N1 - Number of references - 52 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Temperature effects; Microvasculature; Epithelial cells; Adaptations; Replication; Transmission electron microscopy; Tropism; Lung diseases; Infection; Inflammation; Public health; Endothelial cells; Influenza; Pathogenicity; Lung; Cytokines; Immune response; Pneumonia; Respiratory tract; Mortality; Viruses; Temperature; Respiratory diseases; Adaptability; Sulfur dioxide; Microscopy; Seasonal variations; Influenza virus DO - http://dx.doi.org/10.1128/JVI.03095-14 ER - TY - JOUR T1 - HIV-1 vaccines based on replication-competent Tiantan vaccinia protected Chinese rhesus macaques from simian HIV infection AN - 1808629405; PQ0003241713 AB - Objective: To assess the efficacy of HIV vaccines constructed from replication-competent Tiantan vaccinia virus (rTV) alone or combined with DNA in protecting Chinese rhesus macaques from homologous Simian/Human Immunodeficiency Virus (SHIV)-CN97001 challenge. Methods: The nef, gag, pol, and gp140 genes from strain CRF07_BC HIV-1 CN54 were selected to construct an HIV vaccine using the rTV or rTV/DNA vaccine. After vaccination, the vaccine and control groups were intravenously challenged with SHIV-CN97001 (32 MID sub(50)). HIV-specific antibodies and neutralizing antibodies, gp70 V1V2 binding antibodies, and cytotoxic T-lymphocyte responses were measured prospectively after vaccination with an ELISA, a virus infectivity assay in TZM-bl cells, and ELISPOT assays, respectively. Viral RNA was quantified after challenge with real-time reverse transcriptase-PCR (RT-PCR), and protection efficacy was determined with an analysis of CD8 super(+) lymphocyte depletion in vivo. Results: Both rTV and DNA/rTV vaccine groups developed strong cellular and humoral responses against HIV-1 CN54 antigens, including Gag and Env, and also developed significant and persistent anti-Env antibodies and neutralizing antibodies after immunization. Both the rTV and DNA/rTV groups were significantly protected against SHIV-CN97001 or displayed lower viremia than the controls. After CD8 super(+) lymphocyte depletion, no viremia was detectable in the vaccinated monkeys, but rebounded rapidly in the control animals. Protection against infection correlated with vaccine-elicited neutralizing antibodies specific for homologous HIV-1 viruses. Conclusion: An rTV-based HIV-1 vaccine, with or without a DNA primer, provided protection from SHIV challenge in a macaque model. Replication-competent Tiantan vaccinia is a promising vector and should enable advances in HIV-1 vaccine development JF - AIDS AU - Liu, Qiang AU - Li, Yue AU - Luo, Zhenwu AU - Yang, Guibo AU - Liu, Yong AU - Liu, Ying AU - Sun, Maosheng AU - Dai, Jiejie AU - Li, Qihan AU - Qin, Chuan AU - Shao, Yiming AD - State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, yshao08@gmail.com Y1 - 2015/03/27/ PY - 2015 DA - 2015 Mar 27 SP - 649 EP - 658 PB - Lippincott Williams & Wilkins, Inc, 530 Walnut Street Philadelphia PA 19106-3621 United States VL - 29 IS - 6 SN - 0269-9370, 0269-9370 KW - Health & Safety Science Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - HIV-1 KW - replication Tiantan vaccinia KW - simian HIV KW - vaccine KW - Acquired immune deficiency syndrome KW - Viruses KW - Simian/human immunodeficiency virus KW - Lymphocytes KW - Infection KW - DNA vaccines KW - Combined vaccines KW - Human immunodeficiency virus 1 KW - Lymphocytes T KW - Polymerase chain reaction KW - Macaca mulatta KW - Enzyme-linked immunosorbent assay KW - Vaccinia KW - CD8 antigen KW - Nef protein KW - Immunization KW - Gag protein KW - Cytotoxicity KW - Infectivity KW - Antibodies KW - Vaccinia virus KW - RNA KW - Human immunodeficiency virus KW - DNA KW - Primers KW - Vaccines KW - Viremia KW - Corticotropin-releasing hormone KW - V 22360:AIDS and HIV KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808629405?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS&rft.atitle=HIV-1+vaccines+based+on+replication-competent+Tiantan+vaccinia+protected+Chinese+rhesus+macaques+from+simian+HIV+infection&rft.au=Liu%2C+Qiang%3BLi%2C+Yue%3BLuo%2C+Zhenwu%3BYang%2C+Guibo%3BLiu%2C+Yong%3BLiu%2C+Ying%3BSun%2C+Maosheng%3BDai%2C+Jiejie%3BLi%2C+Qihan%3BQin%2C+Chuan%3BShao%2C+Yiming&rft.aulast=Liu&rft.aufirst=Qiang&rft.date=2015-03-27&rft.volume=29&rft.issue=6&rft.spage=649&rft.isbn=&rft.btitle=&rft.title=AIDS&rft.issn=02699370&rft_id=info:doi/10.1097%2FQAD.0000000000000595 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-08-04 N1 - SubjectsTermNotLitGenreText - Enzyme-linked immunosorbent assay; Vaccinia; CD8 antigen; Nef protein; Infection; Gag protein; Antibodies; Infectivity; Cytotoxicity; RNA; DNA vaccines; Combined vaccines; Lymphocytes T; Polymerase chain reaction; Primers; Viremia; Corticotropin-releasing hormone; Acquired immune deficiency syndrome; Human immunodeficiency virus; Viruses; DNA; Lymphocytes; Vaccines; Immunization; Vaccinia virus; Human immunodeficiency virus 1; Simian/human immunodeficiency virus; Macaca mulatta DO - http://dx.doi.org/10.1097/QAD.0000000000000595 ER - TY - JOUR T1 - Computational framework for next-generation sequencing of heterogeneous viral populations using combinatorial pooling AN - 1701474626; PQ0001733169 AB - Motivation: Next-generation sequencing (NGS) allows for analyzing a large number of viral sequences from infected patients, providing an opportunity to implement large-scale molecular surveillance of viral diseases. However, despite improvements in technology, traditional protocols for NGS of large numbers of samples are still highly cost and labor intensive. One of the possible cost-effective alternatives is combinatorial pooling. Although a number of pooling strategies for consensus sequencing of DNA samples and detection of SNPs have been proposed, these strategies cannot be applied to sequencing of highly heterogeneous viral populations.Results: We developed a cost-effective and reliable protocol for sequencing of viral samples, that combines NGS using barcoding and combinatorial pooling and a computational framework including algorithms for optimal virus-specific pools design and deconvolution of individual samples from sequenced pools. Evaluation of the framework on experimental and simulated data for hepatitis C virus showed that it substantially reduces the sequencing costs and allows deconvolution of viral populations with a high accuracy.Availability and implementation: The source code and experimental data sets are available at http://alan.cs.gsu.edu/NGS/?q=content/pooling Supplementary information: Supplementary data are available at Bioinformatics online. JF - Bioinformatics AU - Skums, Pavel AU - Artyomenko, Alexander AU - Glebova, Olga AU - Ramachandran, Sumathi AU - Mandoiu, Ion AU - Campo, David S AU - Dimitrova, Zoya AU - Zelikovsky, Alex AU - Khudyakov, Yury AD - *To whom correspondence should be addressed., kki8@cdc.gov Y1 - 2015/03/01/ PY - 2015 DA - 2015 Mar 01 SP - 682 EP - 690 PB - Oxford University Press, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 31 IS - 5 SN - 1367-4803, 1367-4803 KW - Biochemistry Abstracts 2: Nucleic Acids; Virology & AIDS Abstracts; Biotechnology and Bioengineering Abstracts KW - DNA sequencing KW - Data processing KW - Hepatitis C virus KW - Single-nucleotide polymorphism KW - Nucleotide sequence KW - Algorithms KW - DNA KW - Bioinformatics KW - Computer applications KW - Internet KW - N 14810:Methods KW - V 22400:Human Diseases KW - W 30960:Bioinformatics & Computer Applications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1701474626?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Bioinformatics&rft.atitle=Computational+framework+for+next-generation+sequencing+of+heterogeneous+viral+populations+using+combinatorial+pooling&rft.au=Skums%2C+Pavel%3BArtyomenko%2C+Alexander%3BGlebova%2C+Olga%3BRamachandran%2C+Sumathi%3BMandoiu%2C+Ion%3BCampo%2C+David+S%3BDimitrova%2C+Zoya%3BZelikovsky%2C+Alex%3BKhudyakov%2C+Yury&rft.aulast=Skums&rft.aufirst=Pavel&rft.date=2015-03-01&rft.volume=31&rft.issue=5&rft.spage=682&rft.isbn=&rft.btitle=&rft.title=Bioinformatics&rft.issn=13674803&rft_id=info:doi/10.1093%2Fbioinformatics%2Fbtu726 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-08-01 N1 - Last updated - 2016-07-07 N1 - SubjectsTermNotLitGenreText - DNA sequencing; Data processing; Single-nucleotide polymorphism; Nucleotide sequence; DNA; Algorithms; Bioinformatics; Computer applications; Internet; Hepatitis C virus DO - http://dx.doi.org/10.1093/bioinformatics/btu726 ER - TY - JOUR T1 - Demographic Trends of Sick Leave Absenteeism Among Civil Service Employees at a Federal Agency From 2004 to 2012 AN - 1680447849; PQ0001516813 AB - Objective: To investigate the associations between demographic variables and sick leave use. Methods: We analyzed sick leave use among civil servants at a federal agency (FA) from 2004 to 2012 by demographic and FA-specific variables. We used a mixed methods approach and type III analysis to build a descriptive model of sick leave proportions and demographic variables. Results: Sick absenteeism usage varied significantly (variation of greater than one sick day per year) by sex, Emergency Operations Center response tier, length of service at the FA, age, and general schedule pay grade level. Our final descriptive model contained age, sex, response tier and an interaction term between age and sex. Conclusions: Future studies should examine these associations on smaller time scales, perhaps breaking the data down by month or day of the week. JF - Journal of Occupational and Environmental Medicine AU - Gajewski, Kim AU - Burris, Dara AU - Spears, D Ross AU - Sullivan, Kevin AU - Oyinloye, Oluremi AU - McNeil, Carrie AU - Meechan, Paul AU - Warnock, Eli AU - Trapp, Jonathan AU - Decker, K C AU - Chapman, Sandy AD - Environment, Safety, and Health Compliance Office, ava3@cdc.gov PY - 2015 SP - 277 EP - 283 PB - Williams & Wilkins, 351 W. Camden St. Baltimore MD 21201 United States VL - 57 IS - 3 SN - 1076-2752, 1076-2752 KW - Health & Safety Science Abstracts KW - Demography KW - Age KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1680447849?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Demographic+Trends+of+Sick+Leave+Absenteeism+Among+Civil+Service+Employees+at+a+Federal+Agency+From+2004+to+2012&rft.au=Gajewski%2C+Kim%3BBurris%2C+Dara%3BSpears%2C+D+Ross%3BSullivan%2C+Kevin%3BOyinloye%2C+Oluremi%3BMcNeil%2C+Carrie%3BMeechan%2C+Paul%3BWarnock%2C+Eli%3BTrapp%2C+Jonathan%3BDecker%2C+K+C%3BChapman%2C+Sandy&rft.aulast=Gajewski&rft.aufirst=Kim&rft.date=2015-03-01&rft.volume=57&rft.issue=3&rft.spage=277&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0000000000000347 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-05-01 N1 - Last updated - 2015-12-23 N1 - SubjectsTermNotLitGenreText - Demography; Age DO - http://dx.doi.org/10.1097/JOM.0000000000000347 ER - TY - JOUR T1 - NLRC5 interacts with RIG-I to induce a robust antiviral response against influenza virus infection AN - 1668259115; PQ0001249016 AB - The NLR protein, NLRC5 is an important regulator of MHC class I gene expression, however, the role of NLRC5 in other innate immune responses is less well defined. In the present study, we report that NLRC5 binds RIG-I and that this interaction is critical for robust antiviral responses against influenza virus. Overexpression of NLRC5 in the human lung epithelial cell line, A549, and normal human bronchial epithelial cells resulted in impaired replication of influenza virus A/Puerto Rico/8/34 virus (PR8) and enhanced IFN- beta expression. Influenza virus leads to induction of IFN- beta that drives RIG-I and NLRC5 expression in host cells. Our results suggest that NLRC5 extends and stabilizes influenza virus induced RIG-I expression and delays expression of the viral inhibitor protein NS1. We show that NS1 binds to NLRC5 to suppress its function. Interaction domain mapping revealed that NLRC5 interacts with RIG-I via its N-terminal death domain and that NLRC5 enhanced antiviral activity in an leucine-rich repeat domain independent manner. Taken together, our findings identify a novel role for NLRC5 in RIG-I-mediated antiviral host responses against influenza virus infection, distinguished from the role of NLRC5 in MHC class I gene regulation. JF - European Journal of Immunology AU - Ranjan, Priya AU - Singh, Neetu AU - Kumar, Amrita AU - Neerincx, Andreas AU - Kremmer, Elisabeth AU - Cao, Weiping AU - Davis, William G AU - Katz, Jacqueline M AU - Gangappa, Shivaprakash AU - Lin, Rongtuan AU - Kufer, Thomas A AU - Sambhara, Suryaprakash AD - Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA. Y1 - 2015/03// PY - 2015 DA - March 2015 SP - 758 EP - 772 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 45 IS - 3 SN - 0014-2980, 0014-2980 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts; Immunology Abstracts KW - beta -Interferon KW - Mortality KW - Epithelial cells KW - Replication KW - Immunology KW - Major histocompatibility complex KW - Infection KW - Antiviral activity KW - Influenza KW - Nlr protein KW - Influenza virus KW - ASW, Caribbean Sea, Greater Antilles, Puerto Rico KW - Lung KW - Influenza A virus KW - Proteins KW - Mapping KW - Immune response KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - V 22350:Immunology KW - F 06910:Microorganisms & Parasites UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1668259115?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=European+Journal+of+Immunology&rft.atitle=NLRC5+interacts+with+RIG-I+to+induce+a+robust+antiviral+response+against+influenza+virus+infection&rft.au=Ranjan%2C+Priya%3BSingh%2C+Neetu%3BKumar%2C+Amrita%3BNeerincx%2C+Andreas%3BKremmer%2C+Elisabeth%3BCao%2C+Weiping%3BDavis%2C+William+G%3BKatz%2C+Jacqueline+M%3BGangappa%2C+Shivaprakash%3BLin%2C+Rongtuan%3BKufer%2C+Thomas+A%3BSambhara%2C+Suryaprakash&rft.aulast=Ranjan&rft.aufirst=Priya&rft.date=2015-03-01&rft.volume=45&rft.issue=3&rft.spage=758&rft.isbn=&rft.btitle=&rft.title=European+Journal+of+Immunology&rft.issn=00142980&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Last updated - 2016-04-29 N1 - SubjectsTermNotLitGenreText - beta -Interferon; Influenza; Nlr protein; Epithelial cells; Lung; Replication; Major histocompatibility complex; Immune response; Antiviral activity; Infection; Mortality; Immunology; Proteins; Mapping; Influenza virus; Influenza A virus; ASW, Caribbean Sea, Greater Antilles, Puerto Rico DO - http://dx.doi.org/10.1002/eji.201344412 ER - TY - JOUR T1 - Contribution of the BacT/Alert MB Mycobacterium Bottle to Bloodstream Infection Surveillance in Thailand: Added Yield for Burkholderia pseudomallei AN - 1668252057; PQ0001232693 AB - Community-acquired bloodstream infections cause substantial morbidity and mortality worldwide, but microbiology capacity and surveillance limitations have challenged good descriptions of pathogen distribution in many regions, including Southeast Asia. Active surveillance for bloodstream infections has been conducted in two rural Thailand provinces for >7 years. Blood specimens were divided into two culture bottles, one optimized for aerobic growth (F bottle) and a second for enhanced growth of mycobacteria (MB bottle), and processed with the BactT/Alert 3D system. Because the routine use of MB culture bottles is resource intensive (expensive and requires prolonged incubation), we assessed the added yield of MB bottles by comparing the proportion of pathogens detected by MB versus that by F bottles from 2005 to 2012. Of 63,066 blood cultures, 7,296 (12%) were positive for at least one pathogen; the most common pathogens were Escherichia coli (28%), Burkholderia pseudomallei (11%), Klebsiella pneumoniae (9%), and Staphylococcus aureus (6%). Two bottles improved the yield overall, but the added yield attributable to the MB bottles was limited to a few pathogens. In addition to the detection of mycobacteria and some fungi, MB bottles improved the detection of B. pseudomallei (27% [MB] versus 8% [F]; P < 0.0001), with added benefit if therapy was initiated prior to the blood culture. The targeted use of MB bottles is warranted for patients at risk for mycobacterial and fungal infections and for infection with B. pseudomallei, a common cause of septicemia in Thailand. JF - Journal of Clinical Microbiology AU - Jorakate, Possawat AU - Higdon, Melissa AU - Kaewpan, Anek AU - Makprasert, Sirirat AU - Yuenprakhon, Somkhit AU - Tawisaid, Kittisak AU - Dejsirilert, Surang AU - Whistler, Toni AU - Baggett, Henry C AD - Global Disease Detection, Thailand Ministry of Public Health-U.S. Centers for Disease Control and Prevention (CDC) Collaboration, Nonthaburi, Thailand, hqg0@cdc.gov. Y1 - 2015/03// PY - 2015 DA - March 2015 SP - 910 EP - 914 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 53 IS - 3 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology KW - Burkholderia pseudomallei KW - Blood culture KW - Mortality KW - Septicemia KW - Mycobacterium KW - Fungi KW - Pathogens KW - Infection KW - Morbidity KW - Escherichia coli KW - Staphylococcus aureus KW - Klebsiella pneumoniae KW - J 02400:Human Diseases KW - K 03320:Cell Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1668252057?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Contribution+of+the+BacT%2FAlert+MB+Mycobacterium+Bottle+to+Bloodstream+Infection+Surveillance+in+Thailand%3A+Added+Yield+for+Burkholderia+pseudomallei&rft.au=Jorakate%2C+Possawat%3BHigdon%2C+Melissa%3BKaewpan%2C+Anek%3BMakprasert%2C+Sirirat%3BYuenprakhon%2C+Somkhit%3BTawisaid%2C+Kittisak%3BDejsirilert%2C+Surang%3BWhistler%2C+Toni%3BBaggett%2C+Henry+C&rft.aulast=Jorakate&rft.aufirst=Possawat&rft.date=2015-03-01&rft.volume=53&rft.issue=3&rft.spage=910&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.02008-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Number of references - 20 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Blood culture; Mortality; Septicemia; Fungi; Pathogens; Infection; Morbidity; Burkholderia pseudomallei; Mycobacterium; Escherichia coli; Staphylococcus aureus; Klebsiella pneumoniae DO - http://dx.doi.org/10.1128/JCM.02008-14 ER - TY - JOUR T1 - Effect of use of 13-valent pneumococcal conjugate vaccine in children on invasive pneumococcal disease in children and adults in the USA: analysis of multisite, population-based surveillance AN - 1668250828; PQ0001205004 AB - Background In 2000, seven-valent pneumococcal conjugate vaccine (PCV7) was introduced in the USA and resulted in dramatic reductions in invasive pneumococcal disease (IPD) and moderate increases in non-PCV7 type IPD. In 2010, PCV13 replaced PCV7 in the US immunisation schedule. We aimed to assess the effect of use of PCV13 in children on IPD in children and adults in the USA. Methods We used laboratory-based and population-based data on incidence of IPD from the Active Bacterial Core surveillance (part of the Centers for Disease Control and Prevention's Emerging Infections Program) in a time-series model to compare rates of IPD before and after the introduction of PCV13. Cases of IPD between July 1, 2004, and June 30, 2013, were classified as being caused by the PCV13 serotypes against which PCV7 has no effect (PCV13 minus PCV7). In a time-series model, we used an expected outcomes approach to compare the reported incidence of IPD to that which would have been expected if PCV13 had not replaced PCV7. Findings Compared with incidence expected among children younger than 5 years if PCV7 alone had been continued, incidence of IPD overall declined by 64% (95% interval estimate [95% IE] 59-68) and IPD caused by PCV13 minus PCV7 serotypes declined by 93% (91-94), by July, 2012, to June, 2013. Among adults, incidence of IPD overall also declined by 12-32% and IPD caused by PCV13 minus PCV7 type IPD declined by 58-72%, depending on age. We estimated that over 30000 cases of IPD and 3000 deaths were averted in the first 3 years after the introduction of PCV13. Interpretation PCV13 reduced IPD across all age groups when used routinely in children in the USA. These findings provide reassurance that, similar to PCV7, PCVs with additional serotypes can also prevent transmission to unvaccinated populations. Funding Centers for Disease Control and Prevention. JF - Lancet Infectious Diseases AU - Moore, Matthew R AU - Link-Gelles, Ruth AU - Schaffner, William AU - Lynfield, Ruth AU - Lexau, Catherine AU - Bennett, Nancy M AU - Petit, Susan AU - Zansky, Shelley M AU - Harrison, Lee H AU - Reingold, Arthur AU - Miller, Lisa AU - Scherzinger, Karen AU - Thomas, Ann AU - Farley, Monica M AU - Zell, Elizabeth R AU - Taylor, Thomas H, Jr AU - Pondo, Tracy AU - Rodgers, Loren AU - McGee, Lesley AU - Beall, Bernard AU - Jorgensen, James H AU - Whitney, Cynthia G AD - National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA Y1 - 2015/03// PY - 2015 DA - Mar 2015 SP - 301 EP - 309 PB - Elsevier B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 15 IS - 3 SN - 1473-3099, 1473-3099 KW - Microbiology Abstracts B: Bacteriology KW - Streptococcus pneumoniae KW - Age KW - Serotypes KW - Data processing KW - Disease control KW - Vaccines KW - Children KW - Infection KW - Immunization KW - Models KW - Disease transmission KW - J 02350:Immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1668250828?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Lancet+Infectious+Diseases&rft.atitle=Effect+of+use+of+13-valent+pneumococcal+conjugate+vaccine+in+children+on+invasive+pneumococcal+disease+in+children+and+adults+in+the+USA%3A+analysis+of+multisite%2C+population-based+surveillance&rft.au=Moore%2C+Matthew+R%3BLink-Gelles%2C+Ruth%3BSchaffner%2C+William%3BLynfield%2C+Ruth%3BLexau%2C+Catherine%3BBennett%2C+Nancy+M%3BPetit%2C+Susan%3BZansky%2C+Shelley+M%3BHarrison%2C+Lee+H%3BReingold%2C+Arthur%3BMiller%2C+Lisa%3BScherzinger%2C+Karen%3BThomas%2C+Ann%3BFarley%2C+Monica+M%3BZell%2C+Elizabeth+R%3BTaylor%2C+Thomas+H%2C+Jr%3BPondo%2C+Tracy%3BRodgers%2C+Loren%3BMcGee%2C+Lesley%3BBeall%2C+Bernard%3BJorgensen%2C+James+H%3BWhitney%2C+Cynthia+G&rft.aulast=Moore&rft.aufirst=Matthew&rft.date=2015-03-01&rft.volume=15&rft.issue=3&rft.spage=301&rft.isbn=&rft.btitle=&rft.title=Lancet+Infectious+Diseases&rft.issn=14733099&rft_id=info:doi/10.1016%2FS1473-3099%2814%2971081-3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Number of references - 24 N1 - Last updated - 2015-11-16 N1 - SubjectsTermNotLitGenreText - Age; Data processing; Serotypes; Disease control; Vaccines; Infection; Children; Immunization; Disease transmission; Models; Streptococcus pneumoniae DO - http://dx.doi.org/10.1016/S1473-3099(14)71081-3 ER - TY - JOUR T1 - Methods for surveillance of fetal alcohol syndrome: The Fetal Alcohol Syndrome Surveillance Network II (FASSNetII) - Arizona, Colorado, New York, 2009 - 2014. AN - 1666726036; 25761572 AB - Surveillance of fetal alcohol syndrome (FAS) is important for monitoring the effects of prenatal alcohol exposure and describing the public health burden of this preventable disorder. Building on the infrastructure of the Fetal Alcohol Syndrome Surveillance Network (FASSNet, 1997-2002), in 2009 the Centers for Disease Control and Prevention awarded 5-year cooperative agreements to three states, Arizona, Colorado, and New York, to conduct population-based surveillance of FAS. The Fetal Alcohol Syndrome Surveillance Network II (FASSNetII, 2009-2014) developed a surveillance case definition based on three clinical criteria: characteristic facial features, central nervous system abnormalities, and growth deficiency. FASSNetII modified the FASSNet methods in three important ways: (1) estimation of a period prevalence rather than birth prevalence; (2) surveillance of FAS among school-age children (ages 7-9 years) to better document the central nervous system abnormalities that are not apparent at birth or during infancy; and (3) implementation of an expert clinical review of abstracted data for probable and confirmed cases classified through a computerized algorithm. FASSNetII abstracted data from multiple sources including birth records, medical records from child development centers or other specialty clinics, and administrative databases such as hospital discharge and Medicaid. One challenge of FASSNetII was its limited access to non-medical records. The FAS prevalence that could be estimated was that of the population identified through an encounter with the healthcare system. Clinical and public health programs that identify children affected by FAS provide critical information for targeting preventive, medical and educational services in this vulnerable population. © 2015 Wiley Periodicals, Inc. JF - Birth defects research. Part A, Clinical and molecular teratology AU - O'Leary, Leslie A AU - Ortiz, Linnette AU - Montgomery, April AU - Fox, Deborah J AU - Cunniff, Christopher AU - Ruttenber, Margaret AU - Breen, April AU - Pettygrove, Sydney AU - Klumb, Don AU - Druschel, Charlotte AU - Frías, Jaime L AU - Robinson, Luther K AU - Bertrand, Jacquelyn AU - Ferrara, Kelly AU - Kelly, Maureen AU - Gilboa, Suzanne M AU - Meaney, F John AU - FASSNetII AD - Centers for Disease Control and Prevention, National Center on Birth Defects and Developmental Disabilities, Atlanta, Georgia. ; FASSNetII Y1 - 2015/03// PY - 2015 DA - March 2015 SP - 196 EP - 202 VL - 103 IS - 3 KW - Index Medicus KW - population-based surveillance KW - birth defects KW - clinical review KW - developmental disabilities KW - fetal alcohol syndrome KW - Centers for Disease Control and Prevention (U.S.) KW - Humans KW - Retrospective Studies KW - Child KW - Community Networks KW - United States -- epidemiology KW - Male KW - Female KW - Child, Preschool KW - Epidemiological Monitoring KW - Fetal Alcohol Spectrum Disorders -- epidemiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1666726036?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Birth+defects+research.+Part+A%2C+Clinical+and+molecular+teratology&rft.atitle=Methods+for+surveillance+of+fetal+alcohol+syndrome%3A+The+Fetal+Alcohol+Syndrome+Surveillance+Network+II+%28FASSNetII%29+-+Arizona%2C+Colorado%2C+New+York%2C+2009+-+2014.&rft.au=O%27Leary%2C+Leslie+A%3BOrtiz%2C+Linnette%3BMontgomery%2C+April%3BFox%2C+Deborah+J%3BCunniff%2C+Christopher%3BRuttenber%2C+Margaret%3BBreen%2C+April%3BPettygrove%2C+Sydney%3BKlumb%2C+Don%3BDruschel%2C+Charlotte%3BFr%C3%ADas%2C+Jaime+L%3BRobinson%2C+Luther+K%3BBertrand%2C+Jacquelyn%3BFerrara%2C+Kelly%3BKelly%2C+Maureen%3BGilboa%2C+Suzanne+M%3BMeaney%2C+F+John%3BFASSNetII&rft.aulast=O%27Leary&rft.aufirst=Leslie&rft.date=2015-03-01&rft.volume=103&rft.issue=3&rft.spage=196&rft.isbn=&rft.btitle=&rft.title=Birth+defects+research.+Part+A%2C+Clinical+and+molecular+teratology&rft.issn=1542-0760&rft_id=info:doi/10.1002%2Fbdra.23335 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2015-12-07 N1 - Date created - 2015-03-24 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Cited By: J Pediatr. 2010 Jun;156(6):907-13, 913.e1-2 [20304425] Dev Disabil Res Rev. 2009;15(3):176-92 [19731384] Birth Defects Res A Clin Mol Teratol. 2014 Feb;100(2):67-78 [24591358] Vital Health Stat 11. 2002 May;(246):1-190 [12043359] Pediatrics. 1966 Mar;37(3):403-8 [5906365] Teratology. 2002;66 Suppl 1:S41-9 [12239744] MMWR Morb Mortal Wkly Rep. 2002 May 24;51(20):433-5 [12056499] Lancet. 1973 Jun 9;1(7815):1267-71 [4126070] J Pediatr. 1987 Aug;111(2):267-8 [3612403] MMWR Morb Mortal Wkly Rep. 1993 May 7;42(17):339-41 [8479418] MMWR Morb Mortal Wkly Rep. 1995 Apr 7;44(13):249-51 [7898419] Obstet Gynecol. 1996 Feb;87(2):163-8 [8559516] Alcohol Clin Exp Res. 1995 Dec;19(6):1565-71 [8749828] MMWR Morb Mortal Wkly Rep. 1997 Nov 28;46(47):1118-20 [9393658] Birth Defects Res A Clin Mol Teratol. 2006 Nov;76(11):793-7 [17036307] Paediatr Perinat Epidemiol. 2007 Mar;21(2):179-90 [17302648] Neurotoxicol Teratol. 2011 Mar-Apr;33(2):322-4 [21073947] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1002/bdra.23335 ER - TY - JOUR T1 - Structural and Functional Analysis of Surface Proteins from an A(H3N8) Influenza Virus Isolated from New England Harbor Seals AN - 1664197744; PQ0001232755 AB - In late 2011, an A(H3N8) influenza virus infection resulted in the deaths of 162 New England harbor seals. Virus sequence analysis and virus receptor binding studies highlighted potential markers responsible for mammalian adaptation and a mixed receptor binding preference (S. J. Anthony, J. A. St Leger, K. Pugliares, H. S. Ip, J. M. Chan, Z. W. Carpenter, I. Navarrete-Macias, M. Sanchez-Leon, J. T. Saliki, J. Pedersen, W. Karesh, P. Daszak, R. Rabadan, T. Rowles, W. I. Lipkin, MBio 3:e00166-00112, 2012, http://dx.doi.org/10.1128/mBio.00166-12). Here, we present a detailed structural and biochemical analysis of the surface antigens of the virus. Results obtained with recombinant proteins for both the hemagglutinin and neuraminidase indicate a true avian receptor binding preference. Although the detection of this virus in new species highlights an increased potential for cross-species transmission, our results indicate that the A(H3N8) virus currently poses a low risk to humans. IMPORTANCE Cross-species transmission of zoonotic influenza viruses increases public health concerns. Here, we report a molecular and structural study of the major surface proteins from an A(H3N8) influenza virus isolated from New England harbor seals. The results improve our understanding of these viruses as they evolve and provide important information to aid ongoing risk assessment analyses as these zoonotic influenza viruses continue to circulate and adapt to new hosts. JF - Journal of Virology AU - Yang, Hua AU - Nguyen, Ha T AU - Carney, Paul J AU - Guo, Zhu AU - Chang, Jessie C AU - Jones, Joyce AU - Davis, Charles T AU - Villanueva, Julie M AU - Gubareva, Larisa V AU - Stevens, James AD - Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, fwb4@cdc.gov. Y1 - 2015/03// PY - 2015 DA - March 2015 SP - 2801 EP - 2812 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 89 IS - 5 SN - 0022-538X, 0022-538X KW - Oceanic Abstracts; ASFA 1: Biological Sciences & Living Resources; Health & Safety Science Abstracts; Risk Abstracts; Virology & AIDS Abstracts KW - Risk assessment KW - Hemagglutinins KW - Nucleotide sequence KW - Viruses KW - Biochemical analysis KW - Infection KW - Disease transmission KW - Public health KW - Influenza KW - Antigens KW - USA, New England KW - Structure-function relationships KW - Risk factors KW - Exo- alpha -sialidase KW - Mortality KW - Adaptations KW - Receptors KW - Seals KW - Functional analysis KW - Recombinants KW - Adaptability KW - Influenza virus KW - surface antigens KW - Marine mammals KW - Proteins KW - New species KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - O 1050:Vertebrates, Urochordates and Cephalochordates KW - Q1 08604:Stock assessment and management KW - R2 23060:Medical and environmental health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1664197744?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Virology&rft.atitle=Structural+and+Functional+Analysis+of+Surface+Proteins+from+an+A%28H3N8%29+Influenza+Virus+Isolated+from+New+England+Harbor+Seals&rft.au=Yang%2C+Hua%3BNguyen%2C+Ha+T%3BCarney%2C+Paul+J%3BGuo%2C+Zhu%3BChang%2C+Jessie+C%3BJones%2C+Joyce%3BDavis%2C+Charles+T%3BVillanueva%2C+Julie+M%3BGubareva%2C+Larisa+V%3BStevens%2C+James&rft.aulast=Yang&rft.aufirst=Hua&rft.date=2015-03-01&rft.volume=89&rft.issue=5&rft.spage=2801&rft.isbn=&rft.btitle=&rft.title=Journal+of+Virology&rft.issn=0022538X&rft_id=info:doi/10.1128%2FJVI.02723-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Number of references - 85 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Recombinants; Antigens; Nucleotide sequence; Marine mammals; Viruses; Receptors; Biochemical analysis; Public health; Disease transmission; Risk assessment; Influenza; Adaptations; surface antigens; Structure-function relationships; Risk factors; Hemagglutinins; Exo- alpha -sialidase; Infection; New species; Mortality; Adaptability; Proteins; Seals; Functional analysis; Influenza virus; USA, New England DO - http://dx.doi.org/10.1128/JVI.02723-14 ER - TY - JOUR T1 - Quantification of ricin, RCA and comparison of enzymatic activity in 18 Ricinus communis cultivars by isotope dilution mass spectrometry. AN - 1652434672; 25576235 AB - The seeds of the Ricinus communis (Castor bean) plant are the source of the economically important commodity castor oil. Castor seeds also contain the proteins ricin and R. communis agglutinin (RCA), two toxic lectins that are hazardous to human health. Radial immunodiffusion (RID) and the enzyme linked immunosorbent assay (ELISA) are two antibody-based methods commonly used to quantify ricin and RCA; however, antibodies currently used in these methods cannot distinguish between ricin and RCA due to the high sequence homology of the respective proteins. In this study, a technique combining antibody-based affinity capture with liquid chromatography and multiple reaction monitoring (MRM) mass spectrometry (MS) was used to quantify the amounts of ricin and RCA independently in extracts prepared from the seeds of eighteen representative cultivars of R. communis which were propagated under identical conditions. Additionally, liquid chromatography and MRM-MS was used to determine rRNA N-glycosidase activity for each cultivar and the overall activity in these cultivars was compared to a purified ricin standard. Of the cultivars studied, the average ricin content was 9.3 mg/g seed, the average RCA content was 9.9 mg/g seed, and the enzymatic activity agreed with the activity of a purified ricin reference within 35% relative activity. Published by Elsevier Ltd. JF - Toxicon : official journal of the International Society on Toxinology AU - Schieltz, David M AU - McWilliams, Lisa G AU - Kuklenyik, Zsuzsanna AU - Prezioso, Samantha M AU - Carter, Andrew J AU - Williamson, Yulanda M AU - McGrath, Sara C AU - Morse, Stephen A AU - Barr, John R AD - Clinical Chemistry Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway N.E., MS-F50, Atlanta, GA 30341, USA. ; Division of Foodborne, Waterborne and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Center for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA. ; Clinical Chemistry Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway N.E., MS-F50, Atlanta, GA 30341, USA. Electronic address: jbarr@cdc.gov. Y1 - 2015/03// PY - 2015 DA - March 2015 SP - 72 EP - 83 VL - 95 KW - Plant Extracts KW - 0 KW - Plant Lectins KW - Ricinus communis agglutinin-1 KW - Ricin KW - 9009-86-3 KW - Glycoside Hydrolases KW - EC 3.2.1.- KW - Index Medicus KW - Cultivar KW - RCA KW - Mass spectrometry KW - Quantification KW - Ricinus communis KW - Seeds -- chemistry KW - Glycoside Hydrolases -- metabolism KW - Electrophoresis, Polyacrylamide Gel KW - Chromatography, Liquid KW - Tandem Mass Spectrometry KW - Plant Extracts -- chemistry KW - Immunoassay KW - Castor Bean -- chemistry KW - Castor Bean -- enzymology KW - Ricin -- chemistry KW - Plant Lectins -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1652434672?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicon+%3A+official+journal+of+the+International+Society+on+Toxinology&rft.atitle=Quantification+of+ricin%2C+RCA+and+comparison+of+enzymatic+activity+in+18+Ricinus+communis+cultivars+by+isotope+dilution+mass+spectrometry.&rft.au=Schieltz%2C+David+M%3BMcWilliams%2C+Lisa+G%3BKuklenyik%2C+Zsuzsanna%3BPrezioso%2C+Samantha+M%3BCarter%2C+Andrew+J%3BWilliamson%2C+Yulanda+M%3BMcGrath%2C+Sara+C%3BMorse%2C+Stephen+A%3BBarr%2C+John+R&rft.aulast=Schieltz&rft.aufirst=David&rft.date=2015-03-01&rft.volume=95&rft.issue=&rft.spage=72&rft.isbn=&rft.btitle=&rft.title=Toxicon+%3A+official+journal+of+the+International+Society+on+Toxinology&rft.issn=1879-3150&rft_id=info:doi/10.1016%2Fj.toxicon.2015.01.003 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2015-10-14 N1 - Date created - 2015-02-02 N1 - Date revised - 2017-01-14 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1016/j.toxicon.2015.01.003 ER - TY - JOUR T1 - The Childhood Obesity Research Demonstration Project: A Team Approach for Supporting a Multisite, Multisector Intervention AN - 1780513970; PQ0002687393 AB - Background: Comprehensive multisector, multilevel approaches are needed to address childhood obesity. This article introduces the structure of a multidisciplinary team approach used to support and guide the multisite, multisector interventions implemented as part of the Childhood Obesity Research Demonstration (CORD) project. This article will describe the function, roles, and lessons learned from the CDC-CORD approach to project management. Methods: The CORD project works across multisectors and multilevels in three demonstration communities. Working with principal investigators and their research teams who are engaging multiple stakeholder groups, including community organizations, schools and child care centers, health departments, and healthcare providers, can be a complex endeavor. To best support the community-based research project, scientific and programmatic expertise in a wide range of areas was required. The team was configured based on the skill sets needed to interact with the various levels of staff working with the project. Conclusions: By thoughtful development of the team and processes, an efficient system for supporting the multisite, multisector intervention project sites was developed. The team approach will be formally evaluated at the end of the project period. JF - Childhood Obesity AU - Williams, Nancy AU - Dooyema, Carrie A AU - Foltz, Jennifer L AU - Belay, Brook AU - Blanck, Heidi M AD - Division of Nutrition, Physical Activity, and Obesity, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA. Y1 - 2015/02// PY - 2015 DA - February 2015 SP - 104 EP - 108 PB - Mary Ann Liebert, Inc. Publishers, 140 Huguenot St 3rd Fl New Rochelle NY 10801 United States VL - 11 IS - 1 SN - 2153-2168, 2153-2168 KW - Physical Education Index KW - Obesity KW - Management KW - Day care centers KW - Community health KW - Team sports KW - Associations KW - Work KW - Expertise KW - School health KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1780513970?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Childhood+Obesity&rft.atitle=The+Childhood+Obesity+Research+Demonstration+Project%3A+A+Team+Approach+for+Supporting+a+Multisite%2C+Multisector+Intervention&rft.au=Williams%2C+Nancy%3BDooyema%2C+Carrie+A%3BFoltz%2C+Jennifer+L%3BBelay%2C+Brook%3BBlanck%2C+Heidi+M&rft.aulast=Williams&rft.aufirst=Nancy&rft.date=2015-02-01&rft.volume=11&rft.issue=1&rft.spage=104&rft.isbn=&rft.btitle=&rft.title=Childhood+Obesity&rft.issn=21532168&rft_id=info:doi/10.1089%2Fchi.2014.0063 LA - English DB - Physical Education Index N1 - Date revised - 2016-04-01 N1 - Number of references - 12 N1 - Last updated - 2016-05-13 N1 - SubjectsTermNotLitGenreText - Obesity; Day care centers; Management; Community health; Associations; Team sports; Expertise; Work; School health DO - http://dx.doi.org/10.1089/chi.2014.0063 ER - TY - JOUR T1 - Childhood Obesity Research Demonstration (CORD): The Cross-Site Overview and Opportunities for Interventions Addressing Obesity Community-Wide AN - 1780512333; PQ0002687394 AB - Background: This is the first of a set of articles in this issue on the Childhood Obesity Research Demonstration (CORD) project and provides an overview of the multisite approach and community-wide interventions. Innovative multisetting, multilevel approaches that integrate primary healthcare and public health interventions to improve outcomes for children with obesity need to be evaluated. The CORD project aims to improve BMI and obesity-related behaviors among underserved 2- to 12-year-old children by utilizing these approaches. Methods: The CORD consortium, structure, model terminology and key components, and common measures were solidified in year 1 of the CORD project. Demonstration sites applied the CORD model across communities in years 2 and 3. Evaluation plans for year 4 include site-specific analyses as well as cross-site impact, process, and sustainability evaluations. Results: The CORD approach resulted in commonalities and differences in participant, intervention, comparison, and outcome elements across sites. Products are to include analytic results as well as cost assessment, lessons learned, tools, and materials. Discussion: Foreseen opportunities and challenges arise from the similarities and unique aspects across sites. Communities adapted interventions to fit their local context and build on strengths, but, in turn, this flexibility makes cross-site evaluation challenging. Conclusion: The CORD project represents an evidence-based approach that integrates primary care and public health strategies and evaluates multisetting multilevel interventions, thus adding to the limited research in this field. CORD products will be disseminated to a variety of stakeholders to aid the understanding, prevention, and management of childhood obesity. JF - Childhood Obesity AU - Foltz, Jennifer L AU - Belay, Brook AU - Dooyema, Carrie A AU - Williams, Nancy AU - Blanck, Heidi M AD - Division of Nutrition, Physical Activity, and Obesity, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA. Y1 - 2015/02// PY - 2015 DA - February 2015 SP - 4 EP - 10 PB - Mary Ann Liebert, Inc. Publishers, 140 Huguenot St 3rd Fl New Rochelle NY 10801 United States VL - 11 IS - 1 SN - 2153-2168, 2153-2168 KW - Physical Education Index KW - Evaluation KW - Obesity KW - Preventive health KW - Objectives KW - Flexibility KW - Analysis KW - Strategy KW - Children KW - Public health KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1780512333?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Childhood+Obesity&rft.atitle=Childhood+Obesity+Research+Demonstration+%28CORD%29%3A+The+Cross-Site+Overview+and+Opportunities+for+Interventions+Addressing+Obesity+Community-Wide&rft.au=Foltz%2C+Jennifer+L%3BBelay%2C+Brook%3BDooyema%2C+Carrie+A%3BWilliams%2C+Nancy%3BBlanck%2C+Heidi+M&rft.aulast=Foltz&rft.aufirst=Jennifer&rft.date=2015-02-01&rft.volume=11&rft.issue=1&rft.spage=4&rft.isbn=&rft.btitle=&rft.title=Childhood+Obesity&rft.issn=21532168&rft_id=info:doi/10.1089%2Fchi.2014.0159 LA - English DB - Physical Education Index N1 - Date revised - 2016-04-01 N1 - Number of references - 28 N1 - Last updated - 2016-05-13 N1 - SubjectsTermNotLitGenreText - Evaluation; Obesity; Preventive health; Analysis; Flexibility; Objectives; Strategy; Children; Public health DO - http://dx.doi.org/10.1089/chi.2014.0159 ER - TY - JOUR T1 - HIV STIGMA EXPERIENCED BY YOUNG MEN WHO HAVE SEX WITH MEN (MSM) LIVING WITH HIV INFECTION AN - 1752993587; 201600087 AB - Stigma can compromise the health of persons living with HIV. Although HIV is increasingly affecting young men who have sex with men (MSM), little is known about their experiences with HIV stigma. We used narrative data to examine HIV stigma experienced by young MSM living with HIV. Data came from 28 qualitative interviews with young MSM. We used inductive content analysis to identify themes across these interviews. Participants commonly discussed negative perceptions and treatment of persons living with HIV. Stigma could result in nondisclosure of HIV status, internalized stigma, and avoidance of HIV-related things. Some men discussed strategies that might combat stigma. Findings suggest that HIV stigma might challenge young MSM's health by undermining health-conducive resources (e.g., social support) and contributing to HIV vulnerability. Interventions that counteract HIV stigma may help to create environments that promote well-being among young MSM living with HIV. Adapted from the source document. JF - AIDS Education and Prevention AU - Jeffries, William L AU - Townsend, Ebony Symone AU - Gelaude, Deborah J AU - Torrone, Elizabeth A AU - Gasiorowicz, Mari AU - Bertolli, Jeanne AD - Centers for Disease Control and Prevention, 1600 Clifton Rd., MS E37, Atlanta, GA 30333; Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention wjeffries@cdc.gov Y1 - 2015/02// PY - 2015 DA - February 2015 SP - 58 EP - 71 PB - Guilford Publications, New York NY VL - 27 IS - 1 SN - 0899-9546, 0899-9546 KW - Well Being KW - Males KW - Acquired Immune Deficiency Syndrome KW - Intervention KW - Social Support KW - Health KW - Vulnerability KW - Homosexuality KW - Stigma KW - article KW - 6126: acquired immune deficiency syndrome (AIDS) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1752993587?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocialservices&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+Education+and+Prevention&rft.atitle=HIV+STIGMA+EXPERIENCED+BY+YOUNG+MEN+WHO+HAVE+SEX+WITH+MEN+%28MSM%29+LIVING+WITH+HIV+INFECTION&rft.au=Jeffries%2C+William+L%3BTownsend%2C+Ebony+Symone%3BGelaude%2C+Deborah+J%3BTorrone%2C+Elizabeth+A%3BGasiorowicz%2C+Mari%3BBertolli%2C+Jeanne&rft.aulast=Jeffries&rft.aufirst=William&rft.date=2015-02-01&rft.volume=27&rft.issue=1&rft.spage=58&rft.isbn=&rft.btitle=&rft.title=AIDS+Education+and+Prevention&rft.issn=08999546&rft_id=info:doi/ LA - English DB - Social Services Abstracts N1 - Date revised - 2016-01-01 N1 - Number of references - 28 N1 - Last updated - 2016-09-28 N1 - CODEN - AEPREO N1 - SubjectsTermNotLitGenreText - Acquired Immune Deficiency Syndrome; Stigma; Homosexuality; Health; Well Being; Vulnerability; Intervention; Males; Social Support ER - TY - JOUR T1 - Q Fever is Underestimated in the United States: A Comparison of Fatal Q Fever Cases from Two National Reporting Systems AN - 1722168218; PQ0002108414 AB - Two national surveillance systems capturing reports of fatal Q fever were compared with obtained estimates of Q fever underreporting in the United States using capture-recapture methods. During 2000-2011, a total of 33 unique fatal Q fever cases were reported through case report forms submitted to the Centers for Disease Control and Prevention and through U.S. death certificate data. A single case matched between both data sets, yielding an estimated 129 fatal cases (95% confidence interval [CI] = 62-1,250) during 2000-2011. Fatal cases of Q fever were underreported through case report forms by an estimated factor of 14 and through death certificates by an estimated factor of 5.2. JF - American Journal of Tropical Medicine and Hygiene AU - Dahlgren, F Scott AU - Haberling, Dana L AU - McQuiston, Jennifer H AD - Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, iot0@cdc.gov Y1 - 2015/02// PY - 2015 DA - February 2015 SP - 244 EP - 246 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 92 IS - 2 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Comparative studies KW - USA KW - Data processing KW - Case reports KW - Surveillance and enforcement KW - Disease control KW - Hygiene KW - Q fever KW - K 03400:Human Diseases KW - Q1 08604:Stock assessment and management KW - J 02400:Human Diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1722168218?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Q+Fever+is+Underestimated+in+the+United+States%3A+A+Comparison+of+Fatal+Q+Fever+Cases+from+Two+National+Reporting+Systems&rft.au=Dahlgren%2C+F+Scott%3BHaberling%2C+Dana+L%3BMcQuiston%2C+Jennifer+H&rft.aulast=Dahlgren&rft.aufirst=F&rft.date=2015-02-01&rft.volume=92&rft.issue=2&rft.spage=244&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0502 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Comparative studies; Disease control; Surveillance and enforcement; Hygiene; Data processing; Case reports; Q fever; USA DO - http://dx.doi.org/10.4269/ajtmh.14-0502 ER - TY - JOUR T1 - Incrimination of Aedes (Stegomyia) hensilli Farner as an Epidemic Vector of Chikungunya Virus on Yap Island, Federated States of Micronesia, 2013 AN - 1722166840; PQ0002108443 AB - Two species of Aedes (Stegomyia) were collected in response to the first Chikungunya virus (CHIKV) outbreak on Yap Island: the native species Ae. hensilli Farner and the introduced species Ae. aegypti (L.). Fourteen CHIKV-positive mosquito pools were detected. Six pools were composed of female Ae. hensilli, six pools were composed of female Ae. aegypti, one pool was composed of male Ae. hensilli, and one pool contained female specimens identified as Ae. (Stg.) spp. Infection rates were not significantly different between female Ae. hensilli and Ae. aegypti. The occurrence of human cases in all areas of Yap Island and the greater number of sites that yielded virus from Ae. hensilli combined with the ubiquitous distribution of this species incriminate Ae. hensilli as the most important vector of CHIKV during the outbreak. Phylogenic analysis shows that virus strains on Yap are members of the Asia lineage and closely related to strains currently circulating in the Caribbean. JF - American Journal of Tropical Medicine and Hygiene AU - Savage, Harry M AU - Ledermann, Jeremy P AU - Yug, Laurence AU - Burkhalter, Kristen L AU - Marfel, Maria AU - Hancock, W Thane AD - Centers for Disease Control and Prevention, Fort Collins, Colorado, hms1@cdc.gov Y1 - 2015/02// PY - 2015 DA - February 2015 SP - 429 EP - 436 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 92 IS - 2 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Entomology Abstracts; Virology & AIDS Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Marine KW - Aedes KW - Chikungunya virus KW - Epidemics KW - Caroline I., Micronesia KW - Vectors KW - Hosts KW - Infection KW - Strains KW - Public health KW - Disease transmission KW - Ocean currents KW - Indigenous species KW - ASW, Caribbean Sea KW - Islands KW - ISEW, Caroline Is., Micronesia, Yap I. KW - Micronesia, Fed. States KW - Asia KW - Hygiene KW - Introduced species KW - Aquatic insects KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - Q1 08484:Species interactions: parasites and diseases KW - J 02400:Human Diseases KW - Q5 08524:Public health, medicines, dangerous organisms KW - K 03310:Genetics & Taxonomy KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1722166840?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Incrimination+of+Aedes+%28Stegomyia%29+hensilli+Farner+as+an+Epidemic+Vector+of+Chikungunya+Virus+on+Yap+Island%2C+Federated+States+of+Micronesia%2C+2013&rft.au=Savage%2C+Harry+M%3BLedermann%2C+Jeremy+P%3BYug%2C+Laurence%3BBurkhalter%2C+Kristen+L%3BMarfel%2C+Maria%3BHancock%2C+W+Thane&rft.aulast=Savage&rft.aufirst=Harry&rft.date=2015-02-01&rft.volume=92&rft.issue=2&rft.spage=429&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0374 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Ocean currents; Epidemics; Hosts; Introduced species; Hygiene; Strains; Aquatic insects; Disease transmission; Public health; Indigenous species; Islands; Vectors; Infection; Aedes; Chikungunya virus; ASW, Caribbean Sea; Caroline I., Micronesia; ISEW, Caroline Is., Micronesia, Yap I.; Micronesia, Fed. States; Asia; Marine DO - http://dx.doi.org/10.4269/ajtmh.14-0374 ER - TY - JOUR T1 - The occupational hazards in field operation and the protection measures for epidemic prevention workers AN - 1705067069; PQ0001823485 AB - This article introduces the occupational hazards in field operation for epidemic prevention workers and discusses the principles for protection. Some effective protective measures are put forward. JF - Chinese Journal of Hygienic Insecticides & Equipment AU - DENG, Bing AU - YANG, Hui AU - YANG, Hui-suo AU - WANG, Zheng AD - Center for Disease Control and Prevention of Beijing Command, Beijing 100042, Chirm Y1 - 2015/02// PY - 2015 DA - Feb 2015 SP - 96 EP - 97 PB - Editorial Department of the Chinese Journal of Hygienic Insecticides & Equipment, 293 Zhongshan East Road Nanjing, Jiangsu Province, 210002 China VL - 21 IS - 1 SN - 1671-2781, 1671-2781 KW - Toxicology Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - epidemic prevention workers KW - occupational hazards KW - protective measures KW - Hazards KW - Workers KW - Prevention KW - Epidemics KW - Insecticides KW - Occupational hazards KW - Hygiene KW - R2 23080:Industrial and labor KW - H 1000:Occupational Safety and Health KW - X 24330:Agrochemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1705067069?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chinese+Journal+of+Hygienic+Insecticides+%26+Equipment&rft.atitle=The+occupational+hazards+in+field+operation+and+the+protection+measures+for+epidemic+prevention+workers&rft.au=DENG%2C+Bing%3BYANG%2C+Hui%3BYANG%2C+Hui-suo%3BWANG%2C+Zheng&rft.aulast=DENG&rft.aufirst=Bing&rft.date=2015-02-01&rft.volume=21&rft.issue=1&rft.spage=96&rft.isbn=&rft.btitle=&rft.title=Chinese+Journal+of+Hygienic+Insecticides+%26+Equipment&rft.issn=16712781&rft_id=info:doi/ LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-08-01 N1 - Last updated - 2015-09-30 N1 - SubjectsTermNotLitGenreText - Workers; Insecticides; Epidemics; Occupational hazards; Hygiene; Hazards; Prevention ER - TY - JOUR T1 - Detection of type III secretion system in Vibrio parahaemolyticus from food poison cases and clinical diarrhea patients AN - 1680441787; PQ0001384328 AB - Objective: To investigate the distribution of type III secretion system and antimicrobial resistance of Vibiro parahemolyticus. Methods: The strains were isolated from food poison cases and clinical diarrhea patients. 21 strains were examined for the tdh, trh, T3SS1, T3SS2 alpha , T3SS2 beta and toxR by PCR. The VITEK system was adopted for the detection of antimicrobial resistance. Results: 19 (90.48%) isolates were tdh(+)/trh(-), 1 (4.76%) isolate from clinical diarrhea was tdh(-)/trh(+) and 1(4.76%) strain from food poison cases was tdh(+)/trh(-). T3SS1 existed ubiquitously in the 21 isolates. T3SS2 alpha was shown to be associated with tdh(+)/trh(-), and was found in all the 19 tdh(+)/trh(-) strains. T3SS2 beta was present in tdh(-)/trh(+) strains. The tdh(-)/trh(-) isolate was negative for T3SS2 alpha and T3SS2 beta . All the 21 isolates were sensitive to amoxicillin, cefepime, amikacin, gentamicin, ciprofloxacin and trimethoprim, while resistant to ampicillin. Conclusion: The isolates from different origins were mostly (90.48%) tdh(+). The tdh was associated with T3SS2 alpha and trh with T3SS2 beta . The tdh(-)/trh(-)/T3SS2 alpha (-)/T3SS2 beta (-) isolate indicated that there are other virulence factors remained to be identified. JF - Chinese Journal of Microecology AU - Shao, Zhan-Tao AU - Li, Ying AU - Wang, Yuan-Yuan AU - Zhu, Mei-Juan AU - Wang, Yan-Bo AD - Shunyi District Center for Disease Control and Prevention, Beijing 101300, shaozhantao@hotmail.com PY - 2015 SP - 159 EP - 162 PB - Editorial Department of Chinese Journal of Microecology, 465 Zhongshan Road Dalian 116027 China VL - 27 IS - 2 SN - 1005-376X, 1005-376X KW - Microbiology Abstracts B: Bacteriology KW - Amoxicillin KW - Trimethoprim KW - Diarrhea KW - Amikacin KW - virulence factors KW - Secretion KW - Drug resistance KW - Ampicillin KW - Food poisoning KW - Gentamicin KW - Ciprofloxacin KW - Cefepime KW - Vibrio parahaemolyticus KW - Polymerase chain reaction KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1680441787?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Family+Practice&rft.atitle=Effects+of+educational+outreach+visits+on+prescribing+of+benzodiazepines+and+antipsychotic+drugs+to+elderly+patients+in+primary+health+care+in+southern+Sweden&rft.au=Midl%C3%B6v%2C+Patrik%3BBondesson%2C+%C3%85sa%3BEriksson%2C+Tommy%3BNerbrand%2C+Christina%3BH%C3%B6glund%2C+Peter&rft.aulast=Midl%C3%B6v&rft.aufirst=Patrik&rft.date=2006-02-01&rft.volume=23&rft.issue=1&rft.spage=60&rft.isbn=&rft.btitle=&rft.title=Family+Practice&rft.issn=02632136&rft_id=info:doi/10.1093%2Ffampra%2Fcmi105 LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-05-01 N1 - Last updated - 2016-01-21 N1 - SubjectsTermNotLitGenreText - Trimethoprim; Amoxicillin; Diarrhea; virulence factors; Amikacin; Drug resistance; Secretion; Food poisoning; Ampicillin; Gentamicin; Ciprofloxacin; Cefepime; Polymerase chain reaction; Vibrio parahaemolyticus DO - http://dx.doi.org/10.13381/j.cnki.cjm.201502009 ER - TY - JOUR T1 - Epidemiology of twinning in the National Birth Defects Prevention Study, 1997 to 2007. AN - 1669835855; 25359509 AB - Our objective was to evaluate associations between twinning and maternal demographic factors and periconceptional exposures among infants with and without orofacial clefts. We used data from the National Birth Defects Prevention Study; 228 twins and 8242 singletons without birth defects (controls), and 117 twins and 2859 singletons with orofacial clefts, born 1997 to 2007, were included in the analyses. Because of the occurrence of twinning due to the use of assisted reproductive technologies, logistic regression models were computed to estimate odds ratios and 95% confidence intervals for each exposure, stratified by fertility treatment use. To evaluate factors by zygosity, we used sex-pairing data and a simulation approach to estimate the zygosity of like-sex twin pairs for unassisted conceptions. Among control mothers who did not use fertility treatments, predictors of twinning included non-Hispanic black maternal race (adjusted odds ratio, 1.6; 95% confidence interval, 1.0-2.4), and tobacco smoking (adjusted odds ratio, 1.6; 95% confidence interval, 1.1-2.4). Among control mothers who used fertility treatments, older maternal age, higher income, and state of residence were associated with twinning. Associations were generally stronger among mothers of dizygotic (estimated) twins than monozygotic (estimated) twins. Results for mothers of infants with isolated orofacial clefts were similar to those of controls. We observed an increased twinning frequency with increasing maternal age, but factors such as maternal race/ethnicity and socioeconomic status may also contribute. Among women receiving fertility treatments, factors associated with twinning suggested a relation with treatment specifics (e.g., treatment type and number of embryos implanted) and availability of insurance coverage. © 2014 Wiley Periodicals, Inc. JF - Birth defects research. Part A, Clinical and molecular teratology AU - Dawson, April L AU - Tinker, Sarah C AU - Jamieson, Denise J AU - Hobbs, Charlotte A AU - Rasmussen, Sonja A AU - Reefhuis, Jennita AU - National Birth Defects Prevention Study AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia; Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee. ; National Birth Defects Prevention Study Y1 - 2015/02// PY - 2015 DA - February 2015 SP - 85 EP - 99 VL - 103 IS - 2 KW - Index Medicus KW - ART KW - IVF KW - clomiphene citrate KW - twinning KW - orofacial clefts KW - Odds Ratio KW - Insurance, Health -- statistics & numerical data KW - Humans KW - Retrospective Studies KW - African Americans KW - Pregnancy KW - Smoking -- physiopathology KW - Hispanic Americans KW - Logistic Models KW - Maternal Age KW - European Continental Ancestry Group KW - Adult KW - Health Surveys KW - Income -- statistics & numerical data KW - Case-Control Studies KW - United States -- epidemiology KW - Female KW - Male KW - Cleft Lip -- pathology KW - Cleft Lip -- epidemiology KW - Brain -- abnormalities KW - Cleft Palate -- pathology KW - Reproductive Techniques, Assisted -- statistics & numerical data KW - Cleft Palate -- epidemiology KW - Cleft Lip -- ethnology KW - Brain -- pathology KW - Twins, Dizygotic -- statistics & numerical data KW - Cleft Palate -- ethnology KW - Twins, Monozygotic -- statistics & numerical data UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1669835855?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Birth+defects+research.+Part+A%2C+Clinical+and+molecular+teratology&rft.atitle=Epidemiology+of+twinning+in+the+National+Birth+Defects+Prevention+Study%2C+1997+to+2007.&rft.au=Dawson%2C+April+L%3BTinker%2C+Sarah+C%3BJamieson%2C+Denise+J%3BHobbs%2C+Charlotte+A%3BRasmussen%2C+Sonja+A%3BReefhuis%2C+Jennita%3BNational+Birth+Defects+Prevention+Study&rft.aulast=Dawson&rft.aufirst=April&rft.date=2015-02-01&rft.volume=103&rft.issue=2&rft.spage=85&rft.isbn=&rft.btitle=&rft.title=Birth+defects+research.+Part+A%2C+Clinical+and+molecular+teratology&rft.issn=1542-0760&rft_id=info:doi/10.1002%2Fbdra.23325 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2015-11-16 N1 - Date created - 2015-02-27 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Cited By: Hum Reprod Update. 1999 Mar-Apr;5(2):179-87 [10336022] Am J Med Genet. 1999 Mar 12;83(2):117-24 [10190482] Paediatr Perinat Epidemiol. 2005 Jan;19 Suppl 1:8-9 [15670115] Obstet Gynecol. 2005 Mar;105(3):593-7 [15738030] Matern Child Health J. 2006 Jan;10(1):75-81 [16240077] Med J Aust. 2007 Mar 5;186(5):243-8 [17391087] Hum Reprod. 2008 Aug;23(8):1941-8 [18487216] Reproduction. 2008 Oct;136(4):377-86 [18577552] Twin Res Hum Genet. 2009 Feb;12(1):79-85 [19210182] Fertil Steril. 2010 Feb;93(3):885-93 [19061995] Am J Obstet Gynecol. 2010 Oct;203(4):305-15 [20728073] Eur J Obstet Gynecol Reprod Biol. 2010 Dec;153(2):138-42 [20674134] Birth Defects Res A Clin Mol Teratol. 2011 Jan;91(1):34-8 [20890935] Twin Res Hum Genet. 2011 Feb;14(1):98-103 [21314262] Fertil Steril. 2011 Mar 1;95(3):964-9 [20688327] Hum Reprod. 2011 Aug;26(8):2247-52 [21669967] MMWR Surveill Summ. 2012 Nov 2;61(7):1-23 [23114281] N Engl J Med. 2013 Dec 5;369(23):2218-25 [24304051] Natl Vital Stat Rep. 2013 Jun 28;62(1):1-69, 72 [24974591] Public Health Rep. 2001;116 Suppl 1:32-40 [11889273] Obstet Gynecol. 2000 Jun;95(6 Pt 1):899-904 [10831988] Fertil Steril. 2011 Jul;96(1):95-101 [21616487] Natl Vital Stat Rep. 1999 Sep 14;47(24):1-16 [11968567] Lancet. 2003 Feb 1;361(9355):380-4 [12573374] Birth Defects Res A Clin Mol Teratol. 2003 Mar;67(3):193-201 [12797461] Birth Defects Res A Clin Mol Teratol. 2003 Oct;67(10):879-85 [14745942] BMJ. 2004 Jan 31;328(7434):261 [14742347] JAMA. 2004 Apr 7;291(13):1564-6 [15069042] N Engl J Med. 1977 Sep 1;297(9):468-71 [887128] Vital Health Stat 2. 1980;(83):1-44 [7395112] Acta Genet Med Gemellol (Roma). 1981;30(3):189-202 [6805197] Ann Hum Biol. 1983 Sep-Oct;10(5):409-15 [6638936] Acta Med Scand. 1988;224(5):491-4 [3264449] Acta Genet Med Gemellol (Roma). 1990;39(3):317-28 [2085067] Vital Health Stat 2. 1993 Mar;(116):1-19 [8328134] N Engl J Med. 1994 Jun 9;330(23):1687-8 [8177283] Am J Med Genet. 1997 Jul 11;71(1):93-6 [9215776] N Engl J Med. 1998 Aug 27;339(9):573-7 [9718375] Epidemiology. 1999 Jan;10(1):37-48 [9888278] Behav Genet. 1999 Mar;29(2):115-23 [10405460] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1002/bdra.23325 ER - TY - JOUR T1 - A Multicomponent School‐Based Asthma Management Program: Enhancing Connections to Clinical Care AN - 1665155560 JF - The Journal of School Health AU - Cheung, Karen AU - Rasberry, Catherine N AU - Dunville, Richard L AU - Buckley, Rebekah AU - Cook, Deborah AU - Daniels, Brandy AU - Robin, Leah AD - ICF International karen.cheung@icfi.com Brandy.Daniels@icfi.com; Centers for Disease Control and Prevention, National Center for HIV/AIDS. Viral Hepatitis, STD, and TB Prevention, Division of Adolescent Health RDunville@cdc.gov RDunville@cdc.gov RDunville@cdc.gov; Centers for Disease Control and Prevention. National Center for Chronic Disease Prevention and Health Promotion, Division of Population Health eut9@cdc.gov; Kennett Public Schools ; ICF International Y1 - 2015/02// PY - 2015 DA - Feb 2015 SP - 135 EP - 140 CY - Kent PB - Wiley Subscription Services, Inc. VL - 85 IS - 2 SN - 0022-4391 KW - Physical Fitness And Hygiene KW - Asthma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1665155560?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+School+Health&rft.atitle=A+Multicomponent+School%E2%80%90Based+Asthma+Management+Program%3A+Enhancing+Connections+to+Clinical+Care&rft.au=Cheung%2C+Karen%3BRasberry%2C+Catherine+N%3BDunville%2C+Richard+L%3BBuckley%2C+Rebekah%3BCook%2C+Deborah%3BDaniels%2C+Brandy%3BRobin%2C+Leah&rft.aulast=Cheung&rft.aufirst=Karen&rft.date=2015-02-01&rft.volume=85&rft.issue=2&rft.spage=135&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+School+Health&rft.issn=00224391&rft_id=info:doi/10.1111%2Fjosh.12226 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2015-01-13 N1 - Last updated - 2016-05-12 DO - http://dx.doi.org/10.1111/josh.12226 ER - TY - JOUR T1 - Molecular Mechanisms of Fluconazole Resistance in Candida parapsilosis Isolates from a U.S. Surveillance System AN - 1660441678; PQ0001092240 AB - Candida parapsilosis is the second or third most common cause of candidemia in many countries. The Infectious Diseases Society of America recommends fluconazole as the primary therapy for C. parapsilosis candidemia. Although the rate of fluconazole resistance among C. parapsilosis isolates is low in most U.S. institutions, the resistance rate can be as high as 7.5%. This study was designed to assess the mechanisms of fluconazole resistance in 706 incident bloodstream isolates from U.S. hospitals. We sequenced the ERG11 and MRR1 genes of 122 C. parapsilosis isolates with resistant (30 isolates; 4.2%), susceptible dose-dependent (37 isolates; 5.2%), and susceptible (55 isolates) fluconazole MIC values and used real-time PCR of RNA from 17 isolates to investigate the regulation of MDR1. By comparing these isolates to fully fluconazole-susceptible isolates, we detected at least two mechanisms of fluconazole resistance: an amino acid substitution in the 14- alpha -demethylase gene ERG11 and overexpression of the efflux pump MDR1, possibly due to point mutations in the MRR1 transcription factor that regulates MDR1. The ERG11 single nucleotide polymorphism (SNP) was found in 57% of the fluconazole-resistant isolates and in no susceptible isolates. The MRR1 SNPs were more difficult to characterize, as not all resulted in overexpression of MDR1 and not all MDR1 overexpression was associated with an SNP in MRR1. Further work to characterize the MRR1 SNPs and search for overexpression of other efflux pumps is needed. JF - Antimicrobial Agents & Chemotherapy AU - Grossman, Nina T AU - Pham, Cau D AU - Cleveland, Angela A AU - Lockhart, Shawn R Y1 - 2015/02// PY - 2015 DA - Feb 2015 SP - 1030 EP - 1037 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 59 IS - 2 SN - 0066-4804, 0066-4804 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Molecular modelling KW - Amino acid substitution KW - Candidemia KW - Point mutation KW - MDR1 protein KW - Minimum inhibitory concentration KW - fluconazole KW - RNA KW - Infectious diseases KW - Single-nucleotide polymorphism KW - Transcription factors KW - Polymerase chain reaction KW - Candida parapsilosis KW - Hospitals KW - A 01340:Antibiotics & Antimicrobials KW - K 03400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1660441678?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Molecular+Mechanisms+of+Fluconazole+Resistance+in+Candida+parapsilosis+Isolates+from+a+U.S.+Surveillance+System&rft.au=Grossman%2C+Nina+T%3BPham%2C+Cau+D%3BCleveland%2C+Angela+A%3BLockhart%2C+Shawn+R&rft.aulast=Grossman&rft.aufirst=Nina&rft.date=2015-02-01&rft.volume=59&rft.issue=2&rft.spage=1030&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.04613-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Number of references - 29 N1 - Last updated - 2015-11-16 N1 - SubjectsTermNotLitGenreText - Molecular modelling; Amino acid substitution; Candidemia; Point mutation; MDR1 protein; Minimum inhibitory concentration; fluconazole; Infectious diseases; RNA; Single-nucleotide polymorphism; Transcription factors; Polymerase chain reaction; Hospitals; Candida parapsilosis DO - http://dx.doi.org/10.1128/AAC.04613-14 ER - TY - JOUR T1 - First Report of an Infant Botulism Case Due to Clostridium botulinum Type Af AN - 1660439354; PQ0001092476 AB - Most infant botulism cases worldwide are due to botulinum toxin types A and B. Rarely, Clostridium botulinum strains that produce two serotypes (Ab, Ba, and Bf) have also been isolated from infant botulism cases. This is the first reported case of infant botulism due to C. botulinum type Af worldwide. JF - Journal of Clinical Microbiology AU - de Jong, Laura IT AU - Fernandez, Rafael A AU - Pareja, Virtudes AU - Giaroli, Gabriel AU - Guidarelli, Sergio R AU - Dykes, Janet K AU - Luquez, Carolina AD - Area Microbiologia, Facultad de Ciencias Medicas, Universidad Nacional de Cuyo, Mendoza, Argentina, CLuquez@cdc.gov. PY - 2015 SP - 740 EP - 742 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 53 IS - 2 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Antibodies KW - Serotypes KW - Botulism KW - Clostridium botulinum KW - Botulinum toxin KW - Infants KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1660439354?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=First+Report+of+an+Infant+Botulism+Case+Due+to+Clostridium+botulinum+Type+Af&rft.au=de+Jong%2C+Laura+IT%3BFernandez%2C+Rafael+A%3BPareja%2C+Virtudes%3BGiaroli%2C+Gabriel%3BGuidarelli%2C+Sergio+R%3BDykes%2C+Janet+K%3BLuquez%2C+Carolina&rft.aulast=de+Jong&rft.aufirst=Laura&rft.date=2015-02-01&rft.volume=53&rft.issue=2&rft.spage=740&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.02894-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Number of references - 16 N1 - Last updated - 2016-01-21 N1 - SubjectsTermNotLitGenreText - Antibodies; Serotypes; Botulism; Botulinum toxin; Infants; Clostridium botulinum DO - http://dx.doi.org/10.1128/JCM.02894-14 ER - TY - JOUR T1 - Bacteriophage-Mediated Control of a Two-Species Biofilm Formed by Microorganisms Causing Catheter-Associated Urinary Tract Infections in an In Vitro Urinary Catheter Model AN - 1660438578; PQ0001092180 AB - Microorganisms from a patient or their environment may colonize indwelling urinary catheters, forming biofilm communities on catheter surfaces and increasing patient morbidity and mortality. This study investigated the effect of pretreating hydrogel-coated silicone catheters with mixtures of Pseudomonas aeruginosa and Proteus mirabilis bacteriophages on the development of single- and two-species biofilms in a multiday continuous-flow in vitro model using artificial urine. Novel phages were purified from sewage, characterized, and screened for their abilities to reduce biofilm development by clinical isolates of their respective hosts. Our screening data showed that artificial urine medium (AUM) is a valid substitute for human urine for the purpose of evaluating uropathogen biofilm control by these bacteriophages. Defined phage cocktails targeting P. aeruginosa and P. mirabilis were designed based on the biofilm inhibition screens. Hydrogel-coated catheters were pretreated with one or both cocktails and challenged with approximately 1 103 CFU/ml of the corresponding pathogen(s). The biofilm growth on the catheter surfaces in AUM was monitored over 72 to 96 h. Phage pretreatment reduced P. aeruginosa biofilm counts by 4 log10 CFU/cm2 (P less than or equal to 0.01) and P. mirabilis biofilm counts by >2 log10 CFU/cm2 (P less than or equal to 0.01) over 48 h. The presence of P. mirabilis was always associated with an increase in lumen pH from 7.5 to 9.5 and with eventual blockage of the reactor lines. The results of this study suggest that pretreatment of a hydrogel urinary catheter with a phage cocktail can significantly reduce mixed-species biofilm formation by clinically relevant bacteria. JF - Antimicrobial Agents & Chemotherapy AU - Lehman, Susan M AU - Donlan, Rodney M Y1 - 2015/02// PY - 2015 DA - Feb 2015 SP - 1127 EP - 1137 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 59 IS - 2 SN - 0066-4804, 0066-4804 KW - Virology & AIDS Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Clinical isolates KW - Phages KW - Bacteria KW - Mortality KW - Data processing KW - Silicones KW - Urinary tract KW - Infection KW - Proteus mirabilis KW - Morbidity KW - Models KW - hydrogels KW - Sewage KW - Urine KW - Bioreactors KW - Colony-forming cells KW - Microorganisms KW - Catheters KW - Biofilms KW - Pseudomonas aeruginosa KW - pH effects KW - A 01340:Antibiotics & Antimicrobials KW - V 22340:Antiviral Agents UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1660438578?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Bacteriophage-Mediated+Control+of+a+Two-Species+Biofilm+Formed+by+Microorganisms+Causing+Catheter-Associated+Urinary+Tract+Infections+in+an+In+Vitro+Urinary+Catheter+Model&rft.au=Lehman%2C+Susan+M%3BDonlan%2C+Rodney+M&rft.aulast=Lehman&rft.aufirst=Susan&rft.date=2015-02-01&rft.volume=59&rft.issue=2&rft.spage=1127&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.03786-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Number of references - 70 N1 - Last updated - 2015-11-16 N1 - SubjectsTermNotLitGenreText - Phages; Clinical isolates; Mortality; Data processing; Silicones; Urinary tract; Infection; Morbidity; Models; Sewage; hydrogels; Urine; Colony-forming cells; Bioreactors; Catheters; Microorganisms; Biofilms; pH effects; Bacteria; Pseudomonas aeruginosa; Proteus mirabilis DO - http://dx.doi.org/10.1128/AAC.03786-14 ER - TY - JOUR T1 - Correlates of Sexual Risk for HIV Among US-Born and Foreign-Born Latino Men Who Have Sex with Men (MSM): An Analysis from the Brothers y Hermanos Study AN - 1660405512; PQ0001017019 AB - Little research has been conducted to examine whether correlates of sexual risk vary by nativity among Latino men who have sex with men (MSM). We used cross sectional data collected from 870 Latino MSM recruited with respondent-driven sampling techniques. For each sub-sample (US-born and foreign-born), we assessed the association between each of the potential correlates (substance use, acculturation, social support, and social discrimination) and sexual risk behavior. Illicit drug use was associated with increased odds of sexual risk behavior in both US-born (OR = 2.17, 95 % CI 1.17-4.03) and foreign-born (OR = 1.86, 1.14-3.05) subgroups. Multivariate correlates specific to foreign-born men included binge drinking (OR = 1.91, 1.17-3.14), 15 years or longer spent in the US (OR = 1.79, 1.06-3.03) and exposure to social discrimination (OR = 2.02, 1.03-3.99). Given the diversity of Latino MSM, information from research that identifies both common and different HIV risk factors across subgroups of Latino MSM may help better tailor HIV prevention programs. JF - Journal of Immigrant and Minority Health AU - Mizuno, Yuko AU - Borkowf, Craig B AU - Ayala, George AU - Carballo-Dieguez, Alex AU - Millett, Gregorio A AD - Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road, NE Mail Stop E37, Atlanta, GA, 30333, USA, ymizuno@cdc.gov Y1 - 2015/02// PY - 2015 DA - Feb 2015 SP - 47 EP - 55 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 17 IS - 1 SN - 1557-1912, 1557-1912 KW - Health & Safety Science Abstracts; Risk Abstracts KW - Risk assessment KW - Binge drinking KW - Immigrants KW - Discrimination KW - Homosexuality KW - Drug abuse KW - Substance use KW - Sexual behavior KW - Health risks KW - Prevention KW - Human immunodeficiency virus KW - Risk factors KW - Ethnic groups KW - R2 23060:Medical and environmental health KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1660405512?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Immigrant+and+Minority+Health&rft.atitle=Correlates+of+Sexual+Risk+for+HIV+Among+US-Born+and+Foreign-Born+Latino+Men+Who+Have+Sex+with+Men+%28MSM%29%3A+An+Analysis+from+the+Brothers+y+Hermanos+Study&rft.au=Mizuno%2C+Yuko%3BBorkowf%2C+Craig+B%3BAyala%2C+George%3BCarballo-Dieguez%2C+Alex%3BMillett%2C+Gregorio+A&rft.aulast=Mizuno&rft.aufirst=Yuko&rft.date=2015-02-01&rft.volume=17&rft.issue=1&rft.spage=47&rft.isbn=&rft.btitle=&rft.title=Journal+of+Immigrant+and+Minority+Health&rft.issn=15571912&rft_id=info:doi/10.1007%2Fs10903-013-9894-5 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Number of references - 35 N1 - Last updated - 2015-08-05 N1 - SubjectsTermNotLitGenreText - Risk assessment; Binge drinking; Immigrants; Discrimination; Homosexuality; Drug abuse; Sexual behavior; Substance use; Health risks; Prevention; Human immunodeficiency virus; Risk factors; Ethnic groups DO - http://dx.doi.org/10.1007/s10903-013-9894-5 ER - TY - JOUR T1 - Hypothesis On The Source, Transmission and Characteristics of Infection of Avian Influenza A (H7N9) Virus - Based On Analysis of Field Epidemiological Investigation and Gene Sequence Analysis AN - 1654674074; PQ0001032060 AB - On 31 March 2013, the National Health and Family Planning Commission announced that human infections with influenza A (H7N9) virus had occurred in Shanghai and Anhui provinces, China. H7N9 cases were later detected in Jiangsu and Zhejiang provinces. It was estimated that the virus first spread northward along the route taken by migratory birds and then spread to neighbouring provinces with the sale of poultry. Epidemiological studies were carried out on samples from the external environment of infected cases, transmission routes, farmers markets and live poultry markets. Phylogenetic study of viral sequences from human and avian infections in Zhejiang showed that those from Shanghai and Jiangsu provinces along Taihu Lake were highly homologous with those from the external environment. This suggests that avian viruses carried by waterfowl combined with the virus carried by migratory birds, giving rise to avian influenza virus H7N9, which is highly pathogenic to humans. It is possible that the virus was transmitted by local wildfowl to domestic poultry and then to humans, or spread further by means of trading in wholesale poultry markets. As the weather has turned warm, and with measures adopted to terminate poultry trade and facilitate health communication, the epidemic in the first half of the year has been kept under control. However, the infection source in the triangular area around Taihu Lake still remains. The H7N9 epidemic will probably hit the area later in the year and next spring when the migratory birds return and may even spread to other areas. Great importance should therefore be attached to the wildfowl in Taihu Lake as the repository and disseminator of the virus: investigation and study of this population is essential. JF - Zoonoses and Public Health AU - Ling, F AU - Chen, E AU - Liu, Q AU - Miao, Z AU - Gong, Z AD - Zhejiang Provincial Center for Disease Control and Prevention Y1 - 2015/02// PY - 2015 DA - Feb 2015 SP - 29 EP - 37 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 62 IS - 1 SN - 1863-1959, 1863-1959 KW - Genetics Abstracts; Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Poultry KW - Avian influenza virus KW - Trade KW - Viruses KW - Communication KW - Infection KW - Disease transmission KW - Public health KW - Influenza KW - Lakes KW - China, People's Rep., Jiangsu KW - China, People's Rep., Tai Hu L. KW - Family planning KW - Phylogeny KW - Waterfowl KW - Weather KW - Epidemics KW - Recruitment KW - Population studies KW - Migratory birds KW - Fowl plague KW - Zoonoses KW - Communications KW - Commissions KW - China, People's Rep., Shanghai KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - G 07880:Human Genetics KW - V 22310:Genetics, Taxonomy & Structure UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1654674074?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Zoonoses+and+Public+Health&rft.atitle=Hypothesis+On+The+Source%2C+Transmission+and+Characteristics+of+Infection+of+Avian+Influenza+A+%28H7N9%29+Virus+-+Based+On+Analysis+of+Field+Epidemiological+Investigation+and+Gene+Sequence+Analysis&rft.au=Ling%2C+F%3BChen%2C+E%3BLiu%2C+Q%3BMiao%2C+Z%3BGong%2C+Z&rft.aulast=Ling&rft.aufirst=F&rft.date=2015-02-01&rft.volume=62&rft.issue=1&rft.spage=29&rft.isbn=&rft.btitle=&rft.title=Zoonoses+and+Public+Health&rft.issn=18631959&rft_id=info:doi/10.1111%2Fzph.12110 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-02-01 N1 - Last updated - 2015-09-03 N1 - SubjectsTermNotLitGenreText - Phylogeny; Weather; Poultry; Epidemics; Recruitment; Communication; Population studies; Infection; Public health; Disease transmission; Fowl plague; Lakes; Zoonoses; Family planning; Waterfowl; Trade; Viruses; Migratory birds; Influenza; Communications; Commissions; Avian influenza virus; China, People's Rep., Jiangsu; China, People's Rep., Tai Hu L.; China, People's Rep., Shanghai DO - http://dx.doi.org/10.1111/zph.12110 ER - TY - JOUR T1 - Tuberculosis incidence after 36 months' isoniazid prophylaxis in HIV-infected adults in Botswana: a posttrial observational analysis AN - 1808688689; PQ0003241686 AB - Objective: Thirty-six months of isoniazid preventive therapy (36IPT) was superior to 6 months of IPT (6IPT) in preventing tuberculosis (TB) among HIV-infected adults in Botswana. We assessed the posttrial durability of this benefit. Design: A 36-month double-blind placebo controlled trial (1:1 randomization) with recruitment between November 2004 and July 2006 and observation until June 2011. Methods: One thousand, nine hundred and ninety-five participants were followed in eight public health clinics. Twenty-four percent had a tuberculin skin test > or =5mm (TST-positive). A minimum CD4 super(+) lymphocyte count was not required for enrolment. Antiretroviral therapy (ART) was provided in accordance with Botswana guidelines; 72% of participants retained by June 2011 had initiated ART. Multivariable analysis using Cox regression analysis included treatment arm, TST status, ART as a time-dependent variable and CD4 super(+) cell count at baseline and updated at 36 months. Results: In the posttrial period, 2.13 and 2.14 per 100 person-years accumulated, whereas 0.93 and 1.13% TB incidence rates were observed in the 36IPT and 6IPT arms, respectively (P=0.52). The crude hazard ratio of TB during the trial and posttrial was 0.57 [95% confidence intervals (CI) 0.33, 0.99] and 0.82 (95% CI 0.46, 1.49), and when restricted to TST-positive participants was 0.26 (95% CI 0.08, 0.80) and 0.40 (95% CI 0.15, 1.08), respectively. Multivariable analysis showed that ART use was associated with reduced death (adjusted hazard ratio 0.36, 95% CI 0.17-0.75) but not TB (0.92, 95% CI 0.55-1.53) in the posttrial period. Conclusion: The benefit of 36IPT for TB prevention declined posttrial in this cohort. Adjunctive measures are warranted to prevent TB among HIV-infected persons receiving long-term ART in TB-endemic settings. JF - AIDS AU - Samandari, Taraz AU - Agizew, Tefera B AU - Nyirenda, Samba AU - Tedla, Zegabriel AU - Sibanda, Thabisa AU - Mosimaneotsile, Barudi AU - Motsamai I, Oaitse AU - Shang, Nong AU - Rose, Charles E AU - Shepherd, James AD - Centers for Disease Control and Prevention Botswana, Gaborone and Francistown, Botswana, tts0@cdc.gov Y1 - 2015/01/28/ PY - 2015 DA - 2015 Jan 28 SP - 351 EP - 359 PB - Lippincott Williams & Wilkins, Inc, 530 Walnut Street Philadelphia PA 19106-3621 United States VL - 29 IS - 3 SN - 0269-9370, 0269-9370 KW - Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - antiretroviral therapy KW - HIV KW - isoniazid KW - preventive therapy KW - tuberculin KW - tuberculosis KW - Acquired immune deficiency syndrome KW - Mycobacterium KW - Lymphocytes KW - Clinical trials KW - Public health KW - CD4 antigen KW - Regression analysis KW - Tuberculosis KW - Isoniazid KW - Mortality KW - Cell number KW - Guidelines KW - Recruitment KW - Antiretroviral agents KW - Skin tests KW - Prevention KW - Human immunodeficiency virus KW - Prophylaxis KW - Botswana KW - Tuberculin KW - V 22360:AIDS and HIV KW - J 02400:Human Diseases KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1808688689?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS&rft.atitle=Tuberculosis+incidence+after+36+months%27+isoniazid+prophylaxis+in+HIV-infected+adults+in+Botswana%3A+a+posttrial+observational+analysis&rft.au=Samandari%2C+Taraz%3BAgizew%2C+Tefera+B%3BNyirenda%2C+Samba%3BTedla%2C+Zegabriel%3BSibanda%2C+Thabisa%3BMosimaneotsile%2C+Barudi%3BMotsamai+I%2C+Oaitse%3BShang%2C+Nong%3BRose%2C+Charles+E%3BShepherd%2C+James&rft.aulast=Samandari&rft.aufirst=Taraz&rft.date=2015-01-28&rft.volume=29&rft.issue=3&rft.spage=351&rft.isbn=&rft.btitle=&rft.title=AIDS&rft.issn=02699370&rft_id=info:doi/10.1097%2FQAD.0000000000000535 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-07-01 N1 - Last updated - 2016-09-01 N1 - SubjectsTermNotLitGenreText - CD4 antigen; Cell number; antiretroviral therapy; Regression analysis; Prophylaxis; Tuberculin; Tuberculosis; Skin tests; Public health; Isoniazid; Mortality; Prevention; Acquired immune deficiency syndrome; Recruitment; Guidelines; Lymphocytes; Clinical trials; Antiretroviral agents; Mycobacterium; Human immunodeficiency virus; Botswana DO - http://dx.doi.org/10.1097/QAD.0000000000000535 ER - TY - JOUR T1 - Characterization of Drug-Resistant Influenza A(H7N9) Variants Isolated From an Oseltamivir-Treated Patient in Taiwan AN - 1687690892; PQ0001568789 AB - Background Patients contracting influenza A(H7N9) infection often developed severe disease causing respiratory failure. Neuraminidase (NA) inhibitors (NAIs) are the primary option for treatment, but information on drug-resistance markers for influenza A(H7N9) is limited. Methods Four NA variants of A/Taiwan/1/2013(H7N9) virus containing a single substitution (NA-E119V, NA-I222K, NA-I222R, or NA-R292K) recovered from an oseltamivir-treated patient were tested for NAI susceptibility in vitro; their replicative fitness was evaluated in cell culture, mice, and ferrets. Results NA-R292K led to highly reduced inhibition by oseltamivir and peramivir, while NA-E119V, NA-I222K, and NA-I222R caused reduced inhibition by oseltamivir. Mice infected with any virus showed severe clinical signs with high mortality rates. NA-I222K virus was the most virulent in mice, whereas virus lacking NA change (NA-WT) and NA-R292K virus seemed the least virulent. Sequence analysis suggests that PB2-S714N increased virulence of NA-I222K virus in mice; NS1-K126R, alone or in combination with PB2-V227M, produced contrasting effects in NA-WT and NA-R292K viruses. In ferrets, all viruses replicated to high titers in the upper respiratory tract but produced only mild illness. NA-R292K virus, showed reduced replicative fitness in this animal model. Conclusions Our data highlight challenges in assessment of the replicative fitness of H7N9 NA variants that emerged in NAI-treated patients. JF - Journal of Infectious Diseases AU - Marjuki, Henju AU - Mishin, Vasiliy P AU - Chesnokov, Anton P AU - Jones, Joyce AU - De La Cruz, Juan A AU - Sleeman, Katrina AU - Tamura, Daisuke AU - Nguyen, Ha T AU - Wu, Ho-Sheng AU - Chang, Feng-Yee AD - Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention Y1 - 2015/01/15/ PY - 2015 DA - 2015 Jan 15 SP - 249 EP - 257 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 211 IS - 2 SN - 0022-1899, 0022-1899 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - influenza virus KW - H7N9 KW - oseltamivir KW - peramivir KW - R292K KW - E119V KW - I222K KW - I222R KW - mice KW - ferrets KW - Fitness KW - Mortality KW - Data processing KW - Drug resistance KW - Viruses KW - Animal models KW - Mice KW - Cell culture KW - Infection KW - Oseltamivir KW - Influenza KW - Virulence KW - ISEW, Taiwan KW - Mustela KW - Infectious diseases KW - Exo- alpha -sialidase KW - Respiratory tract KW - V 22410:Animal Diseases KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1687690892?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Characterization+of+Drug-Resistant+Influenza+A%28H7N9%29+Variants+Isolated+From+an+Oseltamivir-Treated+Patient+in+Taiwan&rft.au=Marjuki%2C+Henju%3BMishin%2C+Vasiliy+P%3BChesnokov%2C+Anton+P%3BJones%2C+Joyce%3BDe+La+Cruz%2C+Juan+A%3BSleeman%2C+Katrina%3BTamura%2C+Daisuke%3BNguyen%2C+Ha+T%3BWu%2C+Ho-Sheng%3BChang%2C+Feng-Yee&rft.aulast=Marjuki&rft.aufirst=Henju&rft.date=2015-01-15&rft.volume=211&rft.issue=2&rft.spage=249&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiu447 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-06-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Virulence; Fitness; Influenza; Mortality; Data processing; Drug resistance; Animal models; Cell culture; Exo- alpha -sialidase; Infection; Respiratory tract; Oseltamivir; Infectious diseases; Viruses; Mice; Mustela; ISEW, Taiwan DO - http://dx.doi.org/10.1093/infdis/jiu447 ER - TY - JOUR T1 - ORAL SHEDDING OF MARBURG VIRUS IN EXPERIMENTALLY INFECTED EGYPTIAN FRUIT BATS (ROUSETTUS AEGYPTIACUS) AN - 1837336482; PQ0003751748 AB - Marburg virus (Marburg marburgvirus; MARV) causes sporadic outbreaks of Marburg hemorrhagic fever (MHF) in Africa. The Egyptian fruit bat (Rousettus aegyptiacus) has been identified as a natural reservoir based most-recently on the repeated isolation of MARV directly from bats caught at two locations in southwestern Uganda where miners and tourists separately contracted MHF from 2007-08. Despite learning much about the ecology of MARV through extensive field investigations, there remained unanswered questions such as determining the primary routes of virus shedding and the severity of disease, if any, caused by MARV in infected bats. To answer these questions and others, we experimentally infected captive-bred R. aegyptiacus with MARV under high (biosafety level 4) containment. These experiments have shown infection profiles consistent with R. aegyptiacus being a bona fide natural reservoir host for MARV and demonstrated routes of viral shedding capable of infecting humans and other animals. JF - Journal of Wildlife Diseases AU - Amman, Brian R AU - Jones, Megan E B AU - Sealy, Tara K AU - Uebelhoer, Luke S AU - Schuh, Amy J AU - Bird, Brian H AU - Coleman-Mccray, Joann D AU - Martin, Brock E AU - Nichol, Stuart T AU - Towner, Jonathan S AD - Centers for Disease Control and Prevention, Viral Special Pathogens Branch, 1600 Clifton Rd. NE, Atlanta, Georgia 30333, USA, jit8@cdc.gov Y1 - 2015/01// PY - 2015 DA - January 2015 SP - 113 EP - 124 PB - Allen Press, Inc., 810 East Tenth St. Lawrence KS 66044 United States VL - 51 IS - 1 SN - 0090-3558, 0090-3558 KW - Virology & AIDS Abstracts; Ecology Abstracts KW - Experimental infection KW - Marburg virus KW - Rousettus aegyptiacus KW - shedding KW - transmission KW - Fruits KW - Learning KW - Hemorrhagic fever KW - Infection KW - Marburgvirus KW - V 22410:Animal Diseases KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1837336482?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Wildlife+Diseases&rft.atitle=ORAL+SHEDDING+OF+MARBURG+VIRUS+IN+EXPERIMENTALLY+INFECTED+EGYPTIAN+FRUIT+BATS+%28ROUSETTUS+AEGYPTIACUS%29&rft.au=Amman%2C+Brian+R%3BJones%2C+Megan+E+B%3BSealy%2C+Tara+K%3BUebelhoer%2C+Luke+S%3BSchuh%2C+Amy+J%3BBird%2C+Brian+H%3BColeman-Mccray%2C+Joann+D%3BMartin%2C+Brock+E%3BNichol%2C+Stuart+T%3BTowner%2C+Jonathan+S&rft.aulast=Amman&rft.aufirst=Brian&rft.date=2015-01-01&rft.volume=51&rft.issue=1&rft.spage=113&rft.isbn=&rft.btitle=&rft.title=Journal+of+Wildlife+Diseases&rft.issn=00903558&rft_id=info:doi/10.7589%2F2014-08-198 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-11-01 N1 - Last updated - 2016-11-09 N1 - SubjectsTermNotLitGenreText - Fruits; Learning; Hemorrhagic fever; Infection; Marburgvirus DO - http://dx.doi.org/10.7589/2014-08-198 ER - TY - JOUR T1 - Genetic characterazation of influenza A H3N2 and H7N9 viruses in a mixed infection case in Nanjing, 2013 AN - 1811891381; PQ0003526816 AB - [Objective] To analysis the molecular genetic characteristics of influenza A virus H3N2 and N7N9 viruses in one case of mixed infection. [Methods] Using a set of primers and probes for influenza virus genotyping, specimens were detected by real-time quantitative PCR method. Whole-genome sequences of virus isolates were obtained by second-generation sequencing technology. [Results] In April 2013, one mixed infection with seasonal H3N2 influenza virus and avian influenza H7N9 virus were confirmed in Nanjing, and two mixed viruses were isolated, which named A/Nanjing/M1/2013(H3N2)(M1-H3N2) and A/Nanjing/M2/2013(H7N9)(M2-H7N9), respectively. Some important molecular markers associated with host adaptation and virulence were identified in M2-H7N9 virus. M2-H7N9 virus had substitution Q226L(H3 numbering) in the receptor-binding site of hemagglutinin, which may facilitate the viruses to bind to sialic acid(SA)-2,6-Gal-terminated saccharides that are abundant in human upper respiratory epithelium. There was substitution at position 627(E arrow right K) in the PB2 protein, which enhances the ability of the virus infection on the human. [Conclusion] This study provided a direct evidence for human as "mix vessel" of influenza virus, and the reassortment of seasonal influenza viruses and avian H7N9 viruses should be concerned. JF - Microbiology/Weishengwuxue Tongbao AU - Du, Xue-Fei AU - Ding, Jie AU - Qi, Xian AU - Cui, Lun-Biao AU - Shi, Li-Min AD - Nanjing Center for Disease Control and Prevention Y1 - 2015///0, PY - 2015 DA - 0, 2015 SP - 1788 EP - 1794 PB - Kexue Chubanshe, 16 Donghuang Cheng Genbei Jie Beijing 100717 China VL - 42 IS - 9 SN - 0253-2654, 0253-2654 KW - Virology & AIDS Abstracts; Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Influenza A virus KW - Mixed infection KW - H3N2 subtype KW - H7N9 subtype KW - Adaptations KW - Influenza A KW - Hemagglutinins KW - Genotyping KW - Probes KW - Virulence KW - Fowl plague KW - Polymerase chain reaction KW - Primers KW - Respiratory tract KW - V 22410:Animal Diseases KW - A 01450:Environmental Pollution & Waste Treatment KW - J 02320:Cell Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1811891381?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Microbiology%2FWeishengwuxue+Tongbao&rft.atitle=Genetic+characterazation+of+influenza+A+H3N2+and+H7N9+viruses+in+a+mixed+infection+case+in+Nanjing%2C+2013&rft.au=Du%2C+Xue-Fei%3BDing%2C+Jie%3BQi%2C+Xian%3BCui%2C+Lun-Biao%3BShi%2C+Li-Min&rft.aulast=Du&rft.aufirst=Xue-Fei&rft.date=2015-01-01&rft.volume=42&rft.issue=9&rft.spage=1788&rft.isbn=&rft.btitle=&rft.title=Microbiology%2FWeishengwuxue+Tongbao&rft.issn=02532654&rft_id=info:doi/ LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-08-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Virulence; Fowl plague; Adaptations; Genotyping; Hemagglutinins; Influenza A; Probes; Polymerase chain reaction; Primers; Respiratory tract; Mixed infection; Influenza A virus ER - TY - JOUR T1 - Current and Emerging Legionella Diagnostics for Laboratory and Outbreak Investigations AN - 1753503086; 21328222 JF - Clinical Microbiology Reviews AU - Mercante, Jeffrey W AU - Winchell, Jonas M PY - 2015 SP - 95 EP - 133 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 28 IS - 1 SN - 0893-8512, 0893-8512 KW - Microbiology Abstracts B: Bacteriology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1753503086?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+Microbiology+Reviews&rft.atitle=Current+and+Emerging+Legionella+Diagnostics+for+Laboratory+and+Outbreak+Investigations&rft.au=Mercante%2C+Jeffrey+W%3BWinchell%2C+Jonas+M&rft.aulast=Mercante&rft.aufirst=Jeffrey&rft.date=2015-01-01&rft.volume=28&rft.issue=1&rft.spage=95&rft.isbn=&rft.btitle=&rft.title=Clinical+Microbiology+Reviews&rft.issn=08938512&rft_id=info:doi/10.1128%2FCMR.00029-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-01-01 N1 - Number of references - 595 N1 - Last updated - 2016-01-06 DO - http://dx.doi.org/10.1128/CMR.00029-14 ER - TY - JOUR T1 - HIV epidemic among drug users in China: 1995-2011 AN - 1752989979; 2011-896175 AB - To describe trends in the HIV epidemic among drug users (DUs) in China from 1995 to 2011. Data sets from China's national HIV/AIDS case reporting and sentinel surveillance systems as of December 2011 were used separately for descriptive analysis. Changes in the geographic distribution of the number of HIV cases and HIV prevalence among injecting drug users (IDUs) and non-IDUs were examined. We also analysed changes in HIV prevalence among the broader DU population, and drug use-related behaviours including types of drugs used, recent injecting and recent needle sharing in the context of the rapid scale-up of DU sentinel sites and national harm reduction programmes. The HIV epidemic among China's DUs is still highly concentrated in five provinces. Here, HIV prevalence peaked at 30.3% [95% confidence interval (CI) = 28.6, 32.1] among IDUs in 1999, and then gradually decreased to 10.9% (95% CI = 10.6, 11.2) by 2011. We observed a rapid increase in the use of 'nightclub drugs' among DUs from 1.3% in 2004 to 24.4% in 2011. A decline in recent needle sharing among current IDU from 19.5% (95% CI = 19.4, 19.6) in 2006 to 11.3% (95% CI = 11.2, 11.4) in 2011 was found to be correlated with the rapid scale-up of methadone maintenance treatment (MMT; r(4) = -0.94, P = 0.003) harm reduction efforts. While HIV prevalence and needle sharing among current injecting drug users in China have declined dramatically and are correlated with the scale-up of national harm reduction efforts, the recent, rapid increased use of 'nightclub drugs' presents a new challenge. Adapted from the source document. JF - Addiction AU - Wang, Lan AU - Guo, Wei AU - Li, Dongmin AU - Ding, Zhengwei AU - McGoogan, Jennifer M AU - Wang, Ning AU - Wu, Zunyou AU - Wang, Lu AD - National Center for AIDS/STD Control and Prevention. Chinese Center for Disease Control and Prevention Y1 - 2015/01// PY - 2015 DA - January 2015 SP - 20 EP - 28 PB - Blackwell Publishing, Oxford UK VL - 110 IS - s1 SN - 0965-2140, 0965-2140 KW - Human immunodeficiency virus KW - Population KW - China (People's Republic) KW - Drugs KW - Surveillance KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1752989979?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Addiction&rft.atitle=HIV+epidemic+among+drug+users+in+China%3A+1995-2011&rft.au=Wang%2C+Lan%3BGuo%2C+Wei%3BLi%2C+Dongmin%3BDing%2C+Zhengwei%3BMcGoogan%2C+Jennifer+M%3BWang%2C+Ning%3BWu%2C+Zunyou%3BWang%2C+Lu&rft.aulast=Wang&rft.aufirst=Lan&rft.date=2015-01-01&rft.volume=110&rft.issue=s1&rft.spage=20&rft.isbn=&rft.btitle=&rft.title=Addiction&rft.issn=09652140&rft_id=info:doi/10.1111%2Fadd.12779 LA - English DB - PAIS Index N1 - Date revised - 2016-01-01 N1 - Last updated - 2016-09-28 N1 - CODEN - ADICE5 N1 - SubjectsTermNotLitGenreText - Human immunodeficiency virus; Drugs; China (People's Republic); Population; Surveillance DO - http://dx.doi.org/10.1111/add.12779 ER - TY - JOUR T1 - Who uses methadone services in China? Monitoring the world's largest methadone programme AN - 1752989936; 2011-896176 AB - To describe the data collected by the Chinese methadone maintenance treatment (MMT) system and the characteristics of clients entering the programme. Descriptive study using routinely collected data from the MMT data management system for the period March 2004 and March 2010. Clients who enrolled for services between March 2004 and March 2010. Routinely collected data included: demographic information; drug use, sexual and criminal behaviours; status of infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV) and syphilis; random urine-opiate test results; and the daily methadone dose received. Differences among clients by year were examined. During the period examined, there were 251 974 clients attending 684 clinics in 27 provinces. Overall, the mean age was 34.4 years, 83.8% were male, 70.2% were unemployed, 75% had ever injected drugs, 17% had shared needles and 7.4% were HIV-positive. The profile of clients changed over time, with fewer HIV-positive individuals, fewer injecting drug users, fewer needle-sharers, fewer females and fewer unemployed. Half the clients dropped out within 6 months. The average final dose received was 49.4 mg. The estimated probability of interrupting treatment before 6 months was 52.5%. The profile of clients enrolling in methadone maintenance treatment in China is continually changing and appears to be associated with reduced risk of HIV. High dropout in the programme may limit its effectiveness. The availability of a centralized, real-time data system was extremely useful for monitoring the progress of the Chinese methadone maintenance treatment programme. Adapted from the source document. JF - Addiction AU - Sullivan, Sheena G AU - Wu, Zunyou AU - Rou, Keming AU - Pang, Lin AU - Luo, Wei AU - Wang, Changhe AU - Cao, Xiaobin AU - Yin, Wenyuan AU - Liu, Enwu AU - Mi, Guodong AD - National Center for AIDS/STD Control and Prevention. Chinese Center for Disease Control and Prevention Y1 - 2015/01// PY - 2015 DA - January 2015 SP - 29 EP - 39 PB - Blackwell Publishing, Oxford UK VL - 110 IS - s1 SN - 0965-2140, 0965-2140 KW - Hepatitis KW - Risk KW - Unemployment KW - Human immunodeficiency virus KW - Clinics KW - Syphilis KW - China (People's Republic) KW - Drugs KW - Demographics KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1752989936?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Addiction&rft.atitle=Who+uses+methadone+services+in+China%3F+Monitoring+the+world%27s+largest+methadone+programme&rft.au=Sullivan%2C+Sheena+G%3BWu%2C+Zunyou%3BRou%2C+Keming%3BPang%2C+Lin%3BLuo%2C+Wei%3BWang%2C+Changhe%3BCao%2C+Xiaobin%3BYin%2C+Wenyuan%3BLiu%2C+Enwu%3BMi%2C+Guodong&rft.aulast=Sullivan&rft.aufirst=Sheena&rft.date=2015-01-01&rft.volume=110&rft.issue=s1&rft.spage=29&rft.isbn=&rft.btitle=&rft.title=Addiction&rft.issn=09652140&rft_id=info:doi/10.1111%2Fadd.12781 LA - English DB - PAIS Index N1 - Date revised - 2016-01-01 N1 - Last updated - 2016-09-28 N1 - CODEN - ADICE5 N1 - SubjectsTermNotLitGenreText - Human immunodeficiency virus; Drugs; Unemployment; China (People's Republic); Clinics; Demographics; Syphilis; Hepatitis; Risk DO - http://dx.doi.org/10.1111/add.12781 ER - TY - JOUR T1 - Needle and syringe exchange programmes and prevalence of HIV infection among intravenous drug users in China AN - 1752989898; 2011-896180 AB - To examine the association between needle and syringe exchange programme (NSEP) participation and human immunodeficiency virus (HIV) infection among intravenous drug users (IDUs) in China. Six counties with active NSEP were selected from each of the seven provinces with active NSEP sampled, resulting in a sample of 42 counties in China. Subjects were aged more than 18 years and had injected drugs in the past month before the survey, but were excluded if they were currently enrolled in methadone maintenance treatment in order to avoid mixed effects. HIV prevalence was the primary measure. Odds ratios (ORs), 95% confidence intervals (CIs) and P-values were calculated to evaluate associations between HIV infection and NSEP participation. A total of 3494 IDUs were interviewed, of whom 1928 (55.2%) were NSEP attendees (meaning they had attended NSEP at least once in their life-time). The unadjusted HIV prevalence was 13.9% among NSEP attendees and 16.5% among NSEP non-attendees (meaning IDUs who had never used NSEP services). After adjusting for potential confounders and taking into account the variation between counties, NSEP non-attendees were 1.67 times more likely to be HIV-positive compared to NSEP attendees (OR = 1.67, CI = 1.19-2.32, P = 0.0031). Participation in needle and syringe exchange programmes was associated with a substantially lower risk of HIV infection among intravenous drug users in China. Needle and syringe exchange programmes should be expanded to include those who are needle and syringe exchange programme non-attendees. Adapted from the source document. JF - Addiction AU - Luo, Wei AU - Wu, Zunyou AU - Poundstone, Katharine AU - McGoogan, Jennifer M AU - Dong, Willa AU - Pang, Lin AU - Rou, Keming AU - Wang, Changhe AU - Cao, Xiaobin AD - National Center for AIDS/STD Control and Prevention. Chinese Center for Disease Control and Prevention Y1 - 2015/01// PY - 2015 DA - January 2015 SP - 61 EP - 67 PB - Blackwell Publishing, Oxford UK VL - 110 IS - s1 SN - 0965-2140, 0965-2140 KW - Risk KW - Human immunodeficiency virus KW - Associations KW - Surveys KW - Drugs KW - China (People's Republic) KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1752989898?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Addiction&rft.atitle=Needle+and+syringe+exchange+programmes+and+prevalence+of+HIV+infection+among+intravenous+drug+users+in+China&rft.au=Luo%2C+Wei%3BWu%2C+Zunyou%3BPoundstone%2C+Katharine%3BMcGoogan%2C+Jennifer+M%3BDong%2C+Willa%3BPang%2C+Lin%3BRou%2C+Keming%3BWang%2C+Changhe%3BCao%2C+Xiaobin&rft.aulast=Luo&rft.aufirst=Wei&rft.date=2015-01-01&rft.volume=110&rft.issue=s1&rft.spage=61&rft.isbn=&rft.btitle=&rft.title=Addiction&rft.issn=09652140&rft_id=info:doi/10.1111%2Fadd.12783 LA - English DB - PAIS Index N1 - Date revised - 2016-01-01 N1 - Last updated - 2016-09-28 N1 - CODEN - ADICE5 N1 - SubjectsTermNotLitGenreText - Human immunodeficiency virus; China (People's Republic); Drugs; Associations; Risk; Surveys DO - http://dx.doi.org/10.1111/add.12783 ER - TY - JOUR T1 - Evaluation of Selected Borrelia burgdorferi lp54 Plasmid-Encoded Gene Products Expressed during Mammalian Infection as Antigens To Improve Serodiagnostic Testing for Early Lyme Disease AN - 1746893584; PQ0002295838 AB - Laboratory testing for the diagnosis of Lyme disease is performed primarily by serologic assays and is accurate for detection beyond the acute stage of the infection. Serodiagnostic assays to detect the early stages of infection, however, are limited in their sensitivity, and improvement is warranted. We analyzed a series of Borrelia burgdorferi proteins known to be induced within feeding ticks and/or during mammalian infection for their utility as serodiagnostic markers against a comprehensive panel of Lyme disease patient serum samples. The antigens were assayed for IgM and IgG reactivity in line immunoblots and separately by enzyme-linked immunosorbent assay (ELISA), with a focus on reactivity against early Lyme disease with erythema migrans (EM), early disseminated Lyme neuroborreliosis, and early Lyme carditis patient serum samples. By IgM immunoblotting, we found that recombinant proteins BBA65, BBA70, and BBA73 reacted with early Lyme EM samples at levels comparable to those of the OspC antigen used in the current IgM blotting criteria. Additionally, these proteins reacted with serum samples from patients with early neuroborreliosis and early carditis, suggesting value in detecting early stages of this disease progression. We also found serological reactivity against recombinant proteins BBA69 and BBA73 with early-Lyme-disease samples using IgG immunoblotting and ELISA. Significantly, some samples that had been scored negative by the Centers for Disease Control and Prevention-recommended 2-tiered testing algorithm demonstrated positive reactivity to one or more of the antigens by IgM/IgG immunoblot and ELISA. These results suggest that incorporating additional in vivo-expressed antigens into the current IgM/IgG immunoblotting tier in a recombinant protein platform assay may improve the performance of early-Lyme-disease serologic testing. JF - Clinical and Vaccine Immunology AU - Weiner, Zachary P AU - Crew, Rebecca M AU - Brandt, Kevin S AU - Ullmann, Amy J AU - Schriefer, Martin E AU - Molins, Claudia R AU - Gilmore, Robert D PY - 2015 SP - 1176 EP - 1186 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 22 IS - 11 SN - 1556-679X, 1556-679X KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1746893584?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+and+Vaccine+Immunology&rft.atitle=Evaluation+of+Selected+Borrelia+burgdorferi+lp54+Plasmid-Encoded+Gene+Products+Expressed+during+Mammalian+Infection+as+Antigens+To+Improve+Serodiagnostic+Testing+for+Early+Lyme+Disease&rft.au=Weiner%2C+Zachary+P%3BCrew%2C+Rebecca+M%3BBrandt%2C+Kevin+S%3BUllmann%2C+Amy+J%3BSchriefer%2C+Martin+E%3BMolins%2C+Claudia+R%3BGilmore%2C+Robert+D&rft.aulast=Weiner&rft.aufirst=Zachary&rft.date=2015-01-01&rft.volume=22&rft.issue=11&rft.spage=1176&rft.isbn=&rft.btitle=&rft.title=Clinical+and+Vaccine+Immunology&rft.issn=1556679X&rft_id=info:doi/10.1128%2FCVI.00399-15 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-12-01 N1 - Number of references - 40 N1 - Last updated - 2015-12-23 DO - http://dx.doi.org/10.1128/CVI.00399-15 ER - TY - JOUR T1 - Indirect cohort analysis of 10-valent pneumococcal conjugate vaccine effectiveness against vaccine-type and vaccine-related invasive pneumococcal disease AN - 1746889459; PQ0002312874 AB - We applied the indirect cohort method to estimate effectiveness of 10-valent pneumococcal conjugate vaccine (PCV10) among young children in Brazil. Cases of invasive pneumococcal disease (IPD), i.e., Streptococcus pneumoniae, detected in normally sterile fluid identified through laboratory-based surveillance and previously enrolled in a matched case-control effectiveness study are included. We estimated PCV10 effectiveness using multivariable logistic regression comparing PCV10 vaccination among children with vaccine-type or vaccine-related IPD vs. children with non-vaccine-type disease. The adjusted effectiveness of greater than or equal to 1 doses against vaccine-type (72.8%, 95% confidence interval [CI] [44.1, 86.7]) and vaccine-related (61.3%, 95%CI [14.5, 82.5]) IPD were similar to the effectiveness observed in the original case-control study (which required enrollment >1200 controls). We also found significant protection of greater than or equal to 1 dose against individual vaccine serotypes (14, 6B, 23F, 18C) and against vaccine-related serotype 19A. The indirect cohort methods leverages existing surveillance is a feasible approach for evaluating pneumococcal conjugate vaccines, particularly in resource-limited settings. JF - Vaccine AU - Verani, Jennifer R AU - Domingues, Carla Magda ASantos AU - Moraes, Jose Cassio de AD - National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia PY - 2015 SP - 6145 EP - 6148 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 33 IS - 46 SN - 0264-410X, 0264-410X KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Pneumococcal conjugate vaccine (PCV) KW - Invasive pneumococcal disease (IPD) KW - Vaccine effectiveness KW - Brazil KW - Case-control studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1746889459?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Indirect+cohort+analysis+of+10-valent+pneumococcal+conjugate+vaccine+effectiveness+against+vaccine-type+and+vaccine-related+invasive+pneumococcal+disease&rft.au=Verani%2C+Jennifer+R%3BDomingues%2C+Carla+Magda+ASantos%3BMoraes%2C+Jose+Cassio+de&rft.aulast=Verani&rft.aufirst=Jennifer&rft.date=2015-01-01&rft.volume=33&rft.issue=46&rft.spage=6145&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/10.1016%2Fj.vaccine.2015.10.007 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-12-01 N1 - Number of references - 12 N1 - Last updated - 2015-12-23 DO - http://dx.doi.org/10.1016/j.vaccine.2015.10.007 ER - TY - JOUR T1 - Reduced Sexual Risk Behaviors Among Young Men of Color Who Have Sex with Men: Findings from the Community-Based Organization Behavioral Outcomes of Many Men, Many Voices (CBOP-3MV) Project AN - 1732839235; PQ0002250243 AB - In 2006, the Centers for Disease Control and Prevention (CDC) funded community-based organizations (CBOs) to deliver Many Men, Many Voices (3MV) to young men of color who have sex with men. Although 3MV, a group-level behavioral intervention designed to reduce human immunodeficiency virus (HIV) risk behaviors of black men who have sex with men (MSM), has shown effectiveness when delivered in a controlled research environment, there is limited evidence that the intervention is associated with similar outcomes in "real world" settings. For the current project, CDC funded three CBOs to conduct outcome monitoring of the 3MV intervention to determine if young MSM of color report changes in HIV risk behaviors postintervention. Using a repeated measures design, risk behaviors were collected at baseline and again at 3 and 6 months postintervention. Changes in risk behaviors were assessed using generalized estimating equations. Participants (n=337) reported decreases in sexual risk behaviors at both follow-up time points, such as sex without a condom, sex without a condom and multiple partners, and sex without a condom with serodiscordant or status unknown partners. Results suggest that 3MV may be an effective tool for reducing HIV risk behaviors in this critical target population. JF - Prevention Science AU - Stein, Renee AU - Shapatava, Ekaterine AU - Williams, Weston AU - Griffin, Tanesha AU - Bell, Kelly AU - Lyons, Bridget AU - Uhl, Gary AD - Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road, MS-E59, Atlanta, GA, 30333, USA, arf7@cdc.gov PY - 2015 SP - 1147 EP - 1158 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 16 IS - 8 SN - 1389-4986, 1389-4986 KW - Risk Abstracts KW - Risk assessment KW - Community involvement KW - Males KW - Disease control KW - Risk taking KW - Intervention KW - Homosexuality KW - Sexual behavior KW - Condoms KW - Currents KW - Prevention KW - Behavior KW - Human immunodeficiency virus KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1732839235?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Prevention+Science&rft.atitle=Reduced+Sexual+Risk+Behaviors+Among+Young+Men+of+Color+Who+Have+Sex+with+Men%3A+Findings+from+the+Community-Based+Organization+Behavioral+Outcomes+of+Many+Men%2C+Many+Voices+%28CBOP-3MV%29+Project&rft.au=Stein%2C+Renee%3BShapatava%2C+Ekaterine%3BWilliams%2C+Weston%3BGriffin%2C+Tanesha%3BBell%2C+Kelly%3BLyons%2C+Bridget%3BUhl%2C+Gary&rft.aulast=Stein&rft.aufirst=Renee&rft.date=2015-01-01&rft.volume=16&rft.issue=8&rft.spage=1147&rft.isbn=&rft.btitle=&rft.title=Prevention+Science&rft.issn=13894986&rft_id=info:doi/10.1007%2Fs11121-015-0565-8 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-11-01 N1 - Number of references - 20 N1 - Last updated - 2015-12-23 N1 - SubjectsTermNotLitGenreText - Risk assessment; Males; Community involvement; Disease control; Intervention; Risk taking; Homosexuality; Sexual behavior; Condoms; Prevention; Currents; Behavior; Human immunodeficiency virus DO - http://dx.doi.org/10.1007/s11121-015-0565-8 ER - TY - JOUR T1 - Epidemic characteristics of public health emergencies of infectious diseases in schools in Henan Province, 2013 AN - 1732813214; PQ0002133029 AB - To analyze the characteristics of public health emergencies of infectious diseases in schools in Henan Province, 2013, in order to provide the evidences for making preventive and control strategies. Descriptive epidemiological method was used to analyze the characteristics of public health emergencies of infectious diseases in schools in Henan Province, 2013. Software PHGIS 1.7.0 was applied to make the regional distribution map of the events. Kruskal-Wallis test was utilized to compare the duration for different categories of infectious diseases and the investigation time for health departments. Fifteen infectious diseases emergency events were reported in Henan Province, 2013, among which, 13 events were respiratory infectious diseases, and 2 events were intestinal diseases. A total of 17 170 people were affected, and there were 308 patients, but no patients died, and the attack rate was 1.79%. All the events were distributed in 14 counties of 9 cities. JF - Zhengzhou Daxue Xuebao (Yixue Ban) - Journal of Zhengzhou University. Medical sciences AU - You, Aiguo AU - Yang, Jianhua AU - Zhao, Xiaojing AU - Pan, Jingjing AU - Su, Jia AD - Institute for Infectious Disease Control and Prevention, Henan Provincial Center for Disease Control and Prevention, Zhengzhou 450016, youaiguo11@126.com PY - 2015 SP - 347 EP - 350 PB - Zhengzhou Daxue VL - 50 IS - 3 SN - 1671-6825, 1671-6825 KW - Health & Safety Science Abstracts KW - infectious disease KW - public health emergency KW - epidemic characteristic KW - school health KW - health emergency KW - Henan Province KW - Cities KW - Computer programs KW - Schools KW - Infectious diseases KW - Public health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1732813214?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Zhengzhou+Daxue+Xuebao+%28Yixue+Ban%29+-+Journal+of+Zhengzhou+University.+Medical+sciences&rft.atitle=Epidemic+characteristics+of+public+health+emergencies+of+infectious+diseases+in+schools+in+Henan+Province%2C+2013&rft.au=You%2C+Aiguo%3BYang%2C+Jianhua%3BZhao%2C+Xiaojing%3BPan%2C+Jingjing%3BSu%2C+Jia&rft.aulast=You&rft.aufirst=Aiguo&rft.date=2015-01-01&rft.volume=50&rft.issue=3&rft.spage=347&rft.isbn=&rft.btitle=&rft.title=Zhengzhou+Daxue+Xuebao+%28Yixue+Ban%29+-+Journal+of+Zhengzhou+University.+Medical+sciences&rft.issn=16716825&rft_id=info:doi/10.13705%2Fj.issn.1671-6825.2015.03.010 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-11-01 N1 - Last updated - 2015-12-09 N1 - SubjectsTermNotLitGenreText - Computer programs; Cities; Schools; Infectious diseases; Public health DO - http://dx.doi.org/10.13705/j.issn.1671-6825.2015.03.010 ER - TY - JOUR T1 - Environmental Surveillance for Toxigenic Vibrio cholerae in Surface Waters of Haiti AN - 1722164907; PQ0002059453 AB - Epidemic cholera was reported in Haiti in 2010, with no information available on the occurrence or geographic distribution of toxigenic Vibrio cholerae in Haitian waters. In a series of field visits conducted in Haiti between 2011 and 2013, water and plankton samples were collected at 19 sites. Vibrio cholerae was detected using culture, polymerase chain reaction, and direct viable count methods (DFA-DVC). Cholera toxin genes were detected by polymerase chain reaction in broth enrichments of samples collected in all visits except March 2012. Toxigenic V. cholerae was isolated from river water in 2011 and 2013. Whole genome sequencing revealed that these isolates were a match to the outbreak strain. The DFA-DVC tests were positive for V. cholerae O1 in plankton samples collected from multiple sites. Results of this survey show that toxigenic V. cholerae could be recovered from surface waters in Haiti more than 2 years after the onset of the epidemic. JF - American Journal of Tropical Medicine and Hygiene AU - Kahler, Amy M AU - Haley, Bradd J AU - Chen, Arlene AU - Mull, Bonnie J AU - Tarr, Cheryl L AU - Turnsek, Maryann AU - Katz, Lee S AU - Humphrys, Michael S AU - Derado, Gordana AU - Freeman, Nicole AU - Boncy, Jacques AU - Colwell, Rita R AU - Huq, Anwar AU - Hill, Vincent R AD - Centers for Disease Control and Prevention, Atlanta, Georgia, vhill@cdc.gov Y1 - 2015/01// PY - 2015 DA - January 2015 SP - 118 EP - 125 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 92 IS - 1 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Genomes KW - Rivers KW - Geographical distribution KW - Epidemics KW - Pathogenic bacteria KW - Toxicants KW - Surface water KW - Nucleotide sequence KW - Bacterial diseases KW - Vibrio cholerae KW - Cholera toxin KW - Polymerase chain reaction KW - Cholera KW - Disease detection KW - Hygiene KW - Plankton KW - ASW, Caribbean Sea, Greater Antilles, Haiti KW - Q1 08604:Stock assessment and management KW - J 02400:Human Diseases KW - Q5 08524:Public health, medicines, dangerous organisms KW - K 03310:Genetics & Taxonomy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1722164907?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Environmental+Surveillance+for+Toxigenic+Vibrio+cholerae+in+Surface+Waters+of+Haiti&rft.au=Kahler%2C+Amy+M%3BHaley%2C+Bradd+J%3BChen%2C+Arlene%3BMull%2C+Bonnie+J%3BTarr%2C+Cheryl+L%3BTurnsek%2C+Maryann%3BKatz%2C+Lee+S%3BHumphrys%2C+Michael+S%3BDerado%2C+Gordana%3BFreeman%2C+Nicole%3BBoncy%2C+Jacques%3BColwell%2C+Rita+R%3BHuq%2C+Anwar%3BHill%2C+Vincent+R&rft.aulast=Kahler&rft.aufirst=Amy&rft.date=2015-01-01&rft.volume=92&rft.issue=1&rft.spage=118&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.13-0601 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Geographical distribution; Epidemics; Toxicants; Pathogenic bacteria; Nucleotide sequence; Bacterial diseases; Polymerase chain reaction; Disease detection; Hygiene; Rivers; Genomes; Cholera toxin; Surface water; Cholera; Plankton; Vibrio cholerae; ASW, Caribbean Sea, Greater Antilles, Haiti DO - http://dx.doi.org/10.4269/ajtmh.13-0601 ER - TY - JOUR T1 - Virological Surveillance and Analysis on the Characteristics of HA1 Gene of Influenza a Virus H1N1, Case study of Xinyu City from 2013 to 2014 AN - 1676363320; PQ0001405574 AB - Due to head heavy chain region (HA1) of the HA gene are antigenic sites and receptor binding sites of influenza virus. To understand the characteristics of HA1 genes of influenza virus that can evaluate the preventive effect of the current vaccine strain recommend by WHO. 12 strains of influenza A virus H1N1 isolated in Xinyu from 2013 to 2014 were cultured in MDCK cell in this article. Viral RNA were extracted and HA1 gene were amplified by using RT-PCR. The nucleotide sequences were determined and analyzed. The results showed that there was high homology of HA1 between influenza A virus H1N1 isolates from Xinyu City from 2013 to 2014 and the vaccine strain recommended by WHO, the identity were 97.9% similar to 98.5% in nucleotides sequence. Between 6 strains of influenza A virus H1N1 isolated in Xinyu from 2013 and vaccine strain, 7 similar to 11 amino acids changed, 2 mutated sites of 3 strains in different antigenic determinant sites. The strains from 2014 existed in a branch of the evolutionary tree. The above prompted that the vaccine produced by influenza a virus H1N1 vaccine strain recommended by WHO had protective effect to H1N1 of 2014, had terminate protective effect to part of influenza H1N1 in 2013. The outbreak of influenza H1N1 is possible. We should strengthen prevention and control. JF - Jiyinzuxue yu Yingyong Shengwuxue / Genomics And Applied Biology AU - Pan, Hong AU - Liu, Ruihong AU - Wen, Qi AU - Liu, Qin AU - Zhou, Yingu AU - Xiong, Ying AD - Xinyu Center for Disease Control and Prevention, Xinyu, 338000, meihuayu90@163.com Y1 - 2015 PY - 2015 DA - 2015 SP - 247 EP - 251 PB - Genomics and Applied Biology, Room 111, Editorial office of Genomics and Applied Biology No. 100 Daxue East Road, Nanning City, Guangxi China VL - 34 IS - 2 SN - 1674-568X, 1674-568X KW - Genetics Abstracts; Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Influenza H1N1 virus |a MeSH KW - Hemagglutinin gene |a MeSH KW - Phylogenetic analysis |a MeSH KW - Amino acids KW - Trees KW - Nucleotide sequence KW - Influenza KW - HA1 gene KW - Prevention KW - Case studies KW - Homology KW - RNA KW - Branches KW - Influenza A virus KW - Antigenic determinants KW - Polymerase chain reaction KW - Outbreaks KW - Vaccines KW - Evolution KW - Urban areas KW - G 07760:Viruses & Phages KW - H 4000:Food and Drugs KW - V 22310:Genetics, Taxonomy & Structure UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1676363320?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Jiyinzuxue+yu+Yingyong+Shengwuxue+%2F+Genomics+And+Applied+Biology&rft.atitle=Virological+Surveillance+and+Analysis+on+the+Characteristics+of+HA1+Gene+of+Influenza+a+Virus+H1N1%2C+Case+study+of+Xinyu+City+from+2013+to+2014&rft.au=Pan%2C+Hong%3BLiu%2C+Ruihong%3BWen%2C+Qi%3BLiu%2C+Qin%3BZhou%2C+Yingu%3BXiong%2C+Ying&rft.aulast=Pan&rft.aufirst=Hong&rft.date=2015-01-01&rft.volume=34&rft.issue=2&rft.spage=247&rft.isbn=&rft.btitle=&rft.title=Jiyinzuxue+yu+Yingyong+Shengwuxue+%2F+Genomics+And+Applied+Biology&rft.issn=1674568X&rft_id=info:doi/10.13417%2Fj.gab.034.000247 LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-04-01 N1 - Last updated - 2015-09-30 N1 - SubjectsTermNotLitGenreText - HA1 gene; Amino acids; Branches; RNA; Homology; Nucleotide sequence; Antigenic determinants; Polymerase chain reaction; Vaccines; Evolution; Influenza; Prevention; Case studies; Trees; Outbreaks; Urban areas; Influenza A virus DO - http://dx.doi.org/10.13417/j.gab.034.000247 ER - TY - JOUR T1 - Effect of levofloxacin combining with capreomycin on immune function and liver function of patients with multidrug-resistant tuberculosis AN - 1668259920; PQ0001301252 AB - Objective: To study the effect of levofloxacin combining with capreomycin on immune function and liver function of patients with multidrug-resistant tuberculosis. Methods: 90 patients with multidrug-resistant tuberculosis in our hospital were enrolled and randomly divided into observation group and control group. The observation group received levofloxacin, capreomycin combining with conventional chemotherapy, control group received conventional chemotherapy. Then sputum negative conversion, immune function and liver function index were compared. Results: After treatment, observation group sputum negative conversion rate was significantly higher than control group; CD4 super(+) T cells and IgA, IgG, IgM contents were significantly higher than those of control group; CD8 super(+) T cells was significantly lower than that of control group. No significant differences in serum ALP, ALT, AST, STB, total protein levels were found between two groups. Conclusion: Levofloxacin combining with capreomycin treatment is helpful to kill Mycobacterium tuberculosis, improve immune function and will not increase the burden of liver; it's an ideal method in treating multidrug-resistant tuberculosis. JF - Journal of Hainan Medical University AU - LIU, Jun AU - ZHOU, Rong-zhong AD - Emergency Department, Hubei Provincial Center for Disease Control and Prevention Zaoyang 441200, liujunjzk@163.com Y1 - 2015/01// PY - 2015 DA - Jan 2015 SP - 38 EP - 40 PB - Editorial Board of Journal of Hainan Medical College, Xueyuan Road Haikou Hainan 571101 China VL - 21 IS - 1 SN - 1007-1237, 1007-1237 KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Multidrug-resistant tuberculosis KW - Levofloxacin KW - Capreomycin KW - Immune function KW - Liver function KW - Chemotherapy KW - Drug resistance KW - CD8 antigen KW - CD4 antigen KW - Immunoglobulin A KW - Lymphocytes T KW - Liver KW - Immunoglobulin G KW - Tuberculosis KW - Sputum KW - Immune response KW - Immunoglobulin M KW - Mycobacterium tuberculosis KW - Hospitals KW - J 02400:Human Diseases KW - F 06910:Microorganisms & Parasites UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1668259920?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Hainan+Medical+University&rft.atitle=Effect+of+levofloxacin+combining+with+capreomycin+on+immune+function+and+liver+function+of+patients+with+multidrug-resistant+tuberculosis&rft.au=LIU%2C+Jun%3BZHOU%2C+Rong-zhong&rft.aulast=LIU&rft.aufirst=Jun&rft.date=2015-01-01&rft.volume=21&rft.issue=1&rft.spage=38&rft.isbn=&rft.btitle=&rft.title=Journal+of+Hainan+Medical+University&rft.issn=10071237&rft_id=info:doi/10.13210%2Fj.cnki.jhmu.20141028.013 LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Last updated - 2015-11-16 N1 - SubjectsTermNotLitGenreText - Levofloxacin; Drug resistance; Chemotherapy; CD8 antigen; Immunoglobulin A; CD4 antigen; Capreomycin; Immunoglobulin G; Liver; Lymphocytes T; Tuberculosis; Immune response; Sputum; Immunoglobulin M; Hospitals; Mycobacterium tuberculosis DO - http://dx.doi.org/10.13210/j.cnki.jhmu.20141028.013 ER - TY - JOUR T1 - Prevalence and risk factors for stunting and severe stunting among children under three years old in mid‐western rural areas of China AN - 1665150927 AB - Adequate nutrition is needed to ensure optimum growth and development of infants and young children. Although the national economy has developed rapidly during recent decades in China, malnutrition continues to be a major public health problem. The aim of the present study was undertaken to assess the prevalence and risk factors associated with stunting and severe stunting under 3 years old in mid‐western rural areas in China. A community‐based cross‐sectional survey was carried out in 84 villages in mid‐western provinces of China in 2010. A total of 1260 children were selected for nutritional assessment in terms of stunting and severe stunting using the new World Health Organization growth standards. Hierarchical logistic regression was used to examine the risk factors for adverse nutritional status. The prevalence of stunting and severe stunting was 27.0% and 13.2% respectively. Hierarchical logistic regression analysis showed that the risk factors for stunted children were province of residence, caregiver's education, child's gender, low birthweight and duration of exclusive breastfeeding (<6 months). The risk factors for severe stunting in children aged 0–36 months were province of residence, caregiver's education and child's gender. These results indicate that malnutrition is still a major public health problem among children under 3 years old. The government should implement appropriate nutritional intervention strategies to help reduce the prevalence of malnutrition in children. JF - Child Care, Health and Development AU - Jiang, Y AU - Su, X AU - Wang, C AU - Zhang, L AU - Zhang, X AU - Wang, L AU - Cui, Y AD - National Management Center of 12320 Health Hotline. Chinese Center for Disease Control and Prevention ; National Management Center of 12320 Health Hotline. Chinese Center for Disease Control and Prevention Y1 - 2015/01// PY - 2015 DA - Jan 2015 SP - 45 EP - 51 CY - Oxford PB - Wiley Subscription Services, Inc. VL - 41 IS - 1 SN - 0305-1862 KW - Medical Sciences--Pediatrics KW - Breastfeeding KW - Carers KW - Children KW - Gender KW - Health problems KW - Infants KW - Low birth weight KW - Malnutrition KW - Nutrition KW - Nutritional status KW - Provinces KW - Public health KW - Residence KW - Risk assessment KW - Risk factors UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1665150927?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Child+Care%2C+Health+and+Development&rft.atitle=Prevalence+and+risk+factors+for+stunting+and+severe+stunting+among+children+under+three+years+old+in+mid%E2%80%90western+rural+areas+of+China&rft.au=Jiang%2C+Y%3BSu%2C+X%3BWang%2C+C%3BZhang%2C+L%3BZhang%2C+X%3BWang%2C+L%3BCui%2C+Y&rft.aulast=Jiang&rft.aufirst=Y&rft.date=2015-01-01&rft.volume=41&rft.issue=1&rft.spage=45&rft.isbn=&rft.btitle=&rft.title=Child+Care%2C+Health+and+Development&rft.issn=03051862&rft_id=info:doi/10.1111%2Fcch.12148 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2015-01-09 N1 - Last updated - 2015-12-14 DO - http://dx.doi.org/10.1111/cch.12148 ER - TY - JOUR T1 - Investigations of Mycoplasma pneumoniae Infections in the United States: Trends in Molecular Typing and Macrolide Resistance from 2006 to 2013 AN - 1660389035; 21328480 AB - Mycoplasma pneumoniae is a leading cause of respiratory infections, including community-acquired pneumonia (CAP). Currently, pathogen-specific testing is not routinely performed in the primary care setting, and the United States lacks a systematic surveillance program for M. pneumoniae. Documentation of individual cases and clusters typically occurs only when severe illness and/or failure to improve with empirical antibiotic therapy is observed. Outbreaks, some lasting for extended periods and involving a large number of cases, occur regularly. However, many more likely go unrecognized due to the lack of diagnostic testing and structured reporting. We reviewed data from 17 investigations of cases, small clusters, and outbreaks of M. pneumoniae infections that were supported by the Centers for Disease Control and Prevention (CDC) between 2006 and 2013. We examined 199 M. pneumoniae-positive specimens collected during this time period in order to identify trends in antimicrobial resistance and circulating types. Overall, macrolide resistance was identified in approximately 10% of M. pneumoniae infections occurring during this time period. Typing of strains revealed cocirculation of multiple multilocus variable-number tandem-repeat analysis (MLVA) and P1 types throughout this period, including diversity in types detected within individual outbreaks. Three MLVA types (4572, 3562, and 3662) accounted for 97% of the infections during the study period. A systematic surveillance program is necessary to understand the burden of M. pneumoniae disease in the United States, facilitate case and outbreak identification, and inform appropriate therapeutic and infection control strategies. JF - Journal of Clinical Microbiology AU - Diaz, Maureen H AU - Benitez, Alvaro J AU - Winchell, Jonas M Y1 - 2015/01// PY - 2015 DA - January 2015 SP - 124 EP - 130 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 53 IS - 1 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Typing KW - Data processing KW - Reviews KW - Drug resistance KW - Disease control KW - Antibiotics KW - Mycoplasma pneumoniae KW - Infection KW - Pneumonia KW - J 02310:Genetics & Taxonomy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1660389035?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Investigations+of+Mycoplasma+pneumoniae+Infections+in+the+United+States%3A+Trends+in+Molecular+Typing+and+Macrolide+Resistance+from+2006+to+2013&rft.au=Thompson%2C+Britta+M.%3BKnight%2C+Stephanie+L.&rft.aulast=Thompson&rft.aufirst=Britta&rft.date=2006-01-01&rft.volume=38&rft.issue=1&rft.spage=50&rft.isbn=&rft.btitle=&rft.title=Journal+of+Nutrition+Education+and+Behavior&rft.issn=14994046&rft_id=info:doi/10.1016%2Fj.jneb.2005.11.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Number of references - 34 N1 - Last updated - 2016-07-20 N1 - SubjectsTermNotLitGenreText - Data processing; Typing; Drug resistance; Reviews; Disease control; Antibiotics; Infection; Pneumonia; Mycoplasma pneumoniae DO - http://dx.doi.org/10.1128/JCM.02597-14 ER - TY - JOUR T1 - Harmonization of Bordetella pertussis Real-Time PCR Diagnostics in the United States in 2012 AN - 1660385584; 21328465 AB - Real-time PCR (rt-PCR) is an important diagnostic tool for the identification of Bordetella pertussis, Bordetella holmesii, and Bordetella parapertussis. Most U.S. public health laboratories (USPHLs) target IS481, present in 218 to 238 copies in the B. pertussis genome and 32 to 65 copies in B. holmesii. The CDC developed a multitarget PCR assay to differentiate B. pertussis, B. holmesii, and B. parapertussis and provided protocols and training to 19 USPHLs. The 2012 performance exercise (PE) assessed the capability of USPHLs to detect these three Bordetella species in clinical samples. Laboratories were recruited by the Wisconsin State Proficiency Testing program through the Association of Public Health Laboratories, in partnership with the CDC. Spring and fall PE panels contained 12 samples each of viable Bordetella and non-Bordetella species in saline. Fifty and 53 USPHLs participated in the spring and fall PEs, respectively, using a variety of nucleic acid extraction methods, PCR platforms, and assays. Ninety-six percent and 94% of laboratories targeted IS481 in spring and fall, respectively, in either singleplex or multiplex assays. In spring and fall, respectively, 72% and 79% of USPHLs differentiated B. pertussis and B. holmesii and 68% and 72% identified B. parapertussis. IS481 cycle threshold (CT) values for B. pertussis samples had coefficients of variation (CV) ranging from 10% to 28%. Of the USPHLs that differentiated B. pertussis and B. holmesii, sensitivity was 96% and specificity was 95% for the combined panels. The 2012 PE demonstrated increased harmonization of rt-PCR Bordetella diagnostic protocols in USPHLs compared to that of the previous survey. JF - Journal of Clinical Microbiology AU - Williams, Margaret M AU - Taylor, Thomas H, Jr AU - Warshauer, David M AU - Martin, Monte D AU - Valley, Ann M AU - Tondella, M Lucia AD - Centers for Disease Control and Prevention, Atlanta, Georgia, USA, mwilliams7@cdc.gov. Y1 - 2015/01// PY - 2015 DA - January 2015 SP - 118 EP - 123 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 53 IS - 1 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Genomes KW - Pertussis KW - Bordetella pertussis KW - nucleic acids KW - Bordetella KW - Bordetella holmesii KW - Bordetella parapertussis KW - Polymerase chain reaction KW - Public health KW - Physical training KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1660385584?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Harmonization+of+Bordetella+pertussis+Real-Time+PCR+Diagnostics+in+the+United+States+in+2012&rft.au=Williams%2C+Margaret+M%3BTaylor%2C+Thomas+H%2C+Jr%3BWarshauer%2C+David+M%3BMartin%2C+Monte+D%3BValley%2C+Ann+M%3BTondella%2C+M+Lucia&rft.aulast=Williams&rft.aufirst=Margaret&rft.date=2015-01-01&rft.volume=53&rft.issue=1&rft.spage=118&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.02368-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Number of references - 15 N1 - Last updated - 2016-07-20 N1 - SubjectsTermNotLitGenreText - Genomes; Pertussis; nucleic acids; Polymerase chain reaction; Physical training; Public health; Bordetella pertussis; Bordetella; Bordetella holmesii; Bordetella parapertussis DO - http://dx.doi.org/10.1128/JCM.02368-14 ER - TY - JOUR T1 - Annual risk of tuberculous infection measured using serial skin testing, Orel Oblast, Russia, 1991-2005 AN - 1655746503; PQ0001064051 AB - OBJECTIVE: To compare trends in direct annual risk of tuberculous infection (ARTI) during 1991-2005 in relation to tuberculosis (TB) incidence and to indirect estimates of ARTI derived from the prevalence of tuberculin skin test (TST) positivity in schoolchildren in Orel Oblast, Russia. DESIGN: In 2005, we abstracted annual TST results and vaccination histories from a representative sample of schoolchildren in Orel Oblast, Russia, where bacille Calmette-Guerin (BCG) vaccination and annual TST of children are nearly universal. We calculated direct ARTI based on the percentage of children tested with TST conversions each year, excluding conversions following BCG vaccination. RESULTS: We analysed records from 13 206 children, with a median of 10 recorded TST results per child. The ARTI increased from 0.2% in 1991 to 1.6% in 2000, paralleling trends in TB incidence. Similar results were observed when the ARTI was estimated based on prevalence of infection among children aged 3-5 years using a 12 mm cut-off to define TST positivity. Results differed substantially when 10 or 15 mm cut-offs were used or when prevalence was determined among children aged 6-8 years. CONCLUSION: ARTI measured through TST conversion increased as TB incidence increased in Orel Oblast. ARTI measured through serial TSTs can thus provide an indicator of changing trends in TB incidence. JF - International Journal of Tuberculosis and Lung Disease AU - Yuen, C M AU - Krapivina, T M AU - Kazennyy, B Y AU - Kiryanova, E V AU - Aksenova, V A AU - Gordina, A AU - Finlay, A M AU - Cegielski, J P AD - Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, pcegielski@cdc.gov Y1 - 2015/01// PY - 2015 DA - Jan 2015 SP - 39 EP - 43 PB - International Union Against Tuberculosis and Lung Disease, 68 bvd Saint-Michel Paris 75006 France VL - 19 IS - 1 SN - 1027-3719, 1027-3719 KW - Health & Safety Science Abstracts; Risk Abstracts KW - tuberculous infection KW - tuberculin test KW - Russia KW - Health risks KW - Historical account KW - INW, Russia KW - Mycobacterium KW - Lung KW - Tuberculosis KW - Vaccines KW - Children KW - Infection KW - R2 23060:Medical and environmental health KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1655746503?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Annual+risk+of+tuberculous+infection+measured+using+serial+skin+testing%2C+Orel+Oblast%2C+Russia%2C+1991-2005&rft.au=Yuen%2C+C+M%3BKrapivina%2C+T+M%3BKazennyy%2C+B+Y%3BKiryanova%2C+E+V%3BAksenova%2C+V+A%3BGordina%2C+A%3BFinlay%2C+A+M%3BCegielski%2C+J+P&rft.aulast=Yuen&rft.aufirst=C&rft.date=2015-01-01&rft.volume=19&rft.issue=1&rft.spage=39&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/10.5588%2Fijtld.14.0445 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-02-01 N1 - Last updated - 2015-08-05 N1 - SubjectsTermNotLitGenreText - Historical account; Health risks; Lung; Tuberculosis; Vaccines; Infection; Children; Mycobacterium; INW, Russia; Russia DO - http://dx.doi.org/10.5588/ijtld.14.0445 ER - TY - JOUR T1 - Disparities in Capreomycin Resistance Levels Associated with the rrs A1401G Mutation in Clinical Isolates of Mycobacterium tuberculosis AN - 1654696836; 21328212 AB - As the prevalence of multidrug-resistant and extensively drug-resistant tuberculosis strains continues to rise, so does the need to develop accurate and rapid molecular tests to complement time-consuming growth-based drug susceptibility testing. Performance of molecular methods relies on the association of specific mutations with phenotypic drug resistance and while considerable progress has been made for resistance detection of first-line antituberculosis drugs, rapid detection of resistance for second-line drugs lags behind. The rrs A1401G allele is considered a strong predictor of cross-resistance between the three second-line injectable drugs, capreomycin (CAP), kanamycin, and amikacin. However, discordance is often observed between the rrs A1401G mutation and CAP resistance, with up to 40% of rrs A1401G mutants being classified as CAP susceptible. We measured the MICs to CAP in 53 clinical isolates harboring the rrs A1401G mutation and found that the CAP MICs ranged from 8 mu g/ml to 40 mu g/ml. These results were drastically different from engineered A1401G mutants generated in isogenic Mycobacterium tuberculosis, which exclusively exhibited high-level CAP MICs of 40 mu g/ml. These data support the results of prior studies, which suggest that the critical concentration of CAP (10 mu g/ml) used to determine resistance by indirect agar proportion may be too high to detect all CAP-resistant strains and suggest that a larger percentage of resistant isolates could be identified by lowering the critical concentration. These data also suggest that differences in resistance levels among clinical isolates are possibly due to second site or compensatory mutations located elsewhere in the genome. JF - Antimicrobial Agents & Chemotherapy AU - Reeves, Analise Z AU - Campbell, Patricia J AU - Willby, Melisa J AU - Posey, James E AD - Division of TB Elimination, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, jposey@cdc.gov. Y1 - 2015/01// PY - 2015 DA - Jan 2015 SP - 444 EP - 449 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 59 IS - 1 SN - 0066-4804, 0066-4804 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Genomes KW - Clinical isolates KW - Agar KW - Data processing KW - Amikacin KW - Drug resistance KW - Kanamycin KW - Minimum inhibitory concentration KW - Capreomycin KW - Discordance KW - Tuberculosis KW - Cross-resistance KW - Mutation KW - Mycobacterium tuberculosis KW - A 01350:Microbial Resistance KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1654696836?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Disparities+in+Capreomycin+Resistance+Levels+Associated+with+the+rrs+A1401G+Mutation+in+Clinical+Isolates+of+Mycobacterium+tuberculosis&rft.au=Reeves%2C+Analise+Z%3BCampbell%2C+Patricia+J%3BWillby%2C+Melisa+J%3BPosey%2C+James+E&rft.aulast=Reeves&rft.aufirst=Analise&rft.date=2015-01-01&rft.volume=59&rft.issue=1&rft.spage=444&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.04438-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-02-01 N1 - Number of references - 31 N1 - Last updated - 2015-11-16 N1 - SubjectsTermNotLitGenreText - Clinical isolates; Genomes; Agar; Data processing; Amikacin; Drug resistance; Kanamycin; Minimum inhibitory concentration; Capreomycin; Discordance; Tuberculosis; Mutation; Cross-resistance; Mycobacterium tuberculosis DO - http://dx.doi.org/10.1128/AAC.04438-14 ER - TY - JOUR T1 - Tissue and cellular tropism, pathology and pathogenesis of Ebola and Marburg viruses AN - 1654668676; 21169919 AB - Ebola viruses and Marburg viruses include some of the most virulent and fatal pathogens known to humans. These viruses cause severe haemorrhagic fevers, with case fatality rates in the range 25-90%. The diagnosis of filovirus using formalin-fixed tissues from fatal cases poses a significant challenge. The most characteristic histopathological findings are seen in the liver; however, the findings overlap with many other viral and non-viral haemorrhagic diseases. The need to distinguish filovirus infections from other haemorrhagic fevers, particularly in areas with multiple endemic viral haemorrhagic agents, is of paramount importance. In this review we discuss the current state of knowledge of filovirus infections and their pathogenesis, including histopathological findings, epidemiology, modes of transmission and filovirus entry and spread within host organisms. The pathogenesis of filovirus infections is complex and involves activation of the mononuclear phagocytic system, with release of pro-inflammatory cytokines, chemokines and growth factors, endothelial dysfunction, alterations of the innate and adaptive immune systems, direct organ and endothelial damage from unrestricted viral replication late in infection, and coagulopathy. Although our understanding of the pathogenesis of filovirus infections has rapidly increased in the past few years, many questions remain unanswered. Copyright copyright 2014 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd. JF - Journal of Pathology AU - Martines, Roosecelis Brasil AU - Ng, Dianna L AU - Greer, Patricia W AU - Rollin, Pierre E AU - Zaki, Sherif R AD - Infectious Diseases Pathology Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USA. Y1 - 2015/01// PY - 2015 DA - Jan 2015 SP - 153 EP - 174 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 235 IS - 2 SN - 0022-3417, 0022-3417 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Tissues KW - Marburg virus KW - Chemokines KW - Pathology KW - Immune system KW - Viruses KW - Histopathology KW - Ebola virus KW - Infection KW - Phagocytes KW - Filovirus KW - Cytokines KW - Growth factors KW - Mortality KW - Replication KW - ANE, Eire KW - Tropism KW - Pathogens KW - Organs KW - Inflammation KW - Epidemiology KW - Reviews KW - Liver KW - Hemorrhagic fever KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - V 22320:Replication UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1654668676?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Pathology&rft.atitle=Tissue+and+cellular+tropism%2C+pathology+and+pathogenesis+of+Ebola+and+Marburg+viruses&rft.au=Martines%2C+Roosecelis+Brasil%3BNg%2C+Dianna+L%3BGreer%2C+Patricia+W%3BRollin%2C+Pierre+E%3BZaki%2C+Sherif+R&rft.aulast=Martines&rft.aufirst=Roosecelis&rft.date=2015-01-01&rft.volume=235&rft.issue=2&rft.spage=153&rft.isbn=&rft.btitle=&rft.title=Journal+of+Pathology&rft.issn=00223417&rft_id=info:doi/10.1002%2Fpath.4456 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-02-01 N1 - Last updated - 2015-08-05 N1 - SubjectsTermNotLitGenreText - Chemokines; Replication; Immune system; Tropism; Pathogens; Infection; Inflammation; Epidemiology; Phagocytes; Liver; Hemorrhagic fever; Cytokines; Growth factors; Mortality; Tissues; Pathology; Reviews; Viruses; Histopathology; Organs; Marburg virus; Filovirus; Ebola virus; ANE, Eire DO - http://dx.doi.org/10.1002/path.4456 ER - TY - JOUR T1 - Outcomes of pediatric severe traumatic brain injury patients treated in adult trauma centers with and without added qualifications in pediatrics - United States, 2009 AN - 1855073181; PQ0001930683 AB - Background: Pediatric traumatic brain injury (TBI) is an important public health problem and little is known about site of care and outcomes of children with severe TBI. Across the country, most injured children are treated in adult trauma centers (ATCs). Recent literature suggests that ATCs with added qualifications in pediatrics (ATC-AQs) can have improved outcomes for pediatric trauma patients overall. This study characterizes the population of pediatric severe TBI patients treated at ATCs and investigates the effect of treatment at ATC-AQs versus ATCs on mortality. Methods: Using the 2009 National Trauma Data Bank, pediatric (age 0-17 years old) severe TBI (head Abbreviated Injury Scale score greater than or equal to 3) patient visits at level I and II ATCs and ATC-AQs were analyzed for patient and hospital characteristics. The primary outcome was in-patient mortality. Multivariate analysis was performed on propensity score weighted populations to investigate effect of treatment at ATC-AQs versus ATCs on survival. Results: A total of 7,057 pediatric severe TBI patient visits in 398 level I and II trauma centers were observed, with 3,496 (49.5%) at ATC-AQs and 3,561 (50.5%) at ATCs. The mortality rate was 8.6% at ATC-AQs versus 10.3% at ATCs (p =0.0144). After adjusting for differences in case mix, patient, and hospital characteristics, mortality was not significantly different for patients treated in ATC-AQs versus ATCs (aOR=0.896, 95% CI=0.629-1.277). Mortality was significantly associated with age, length of hospital stay, firearm injury, GCS score, and head AIS (p <0.0001). Higher mortality odds were also associated with being uninsured (aOR=2.102, 95% CI=1.159-3.813), and the presence of additional non-TBI severe injuries (aOR=1.936 95% CI=1.175-3.188). Conclusions: After defining comparable populations, this study demonstrated no significant difference in mortality for pediatric severe TBI patients treated at ATC-AQs versus ATCs. Being younger, uninsured, and having severe injuries was associated with increased mortality. This study is limited by the exclusion of transferred patients and potentially underestimates differences in outcomes. Further research is needed to clarify the role of ATC additional pediatric qualifications in the treatment of severe TBI. JF - Injury Epidemiology AU - Ovalle, Fernando AU - Xu, Likang AU - Pearson, William S AU - Spelke, Bridget AU - Sugerman, David E AD - Division of Injury Response, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, 4470 Buford Highway NE, MS-F62, Atlanta, GA, 30341, USA, ggi4@cdc.gov Y1 - 2014/12// PY - 2014 DA - December 2014 SP - 1 EP - 10 PB - Springer Science & Business Media, Cham VL - 1 IS - 1 KW - Biotechnology and Bioengineering Abstracts KW - Mortality KW - Age KW - Injuries KW - Head KW - Pediatrics KW - Survival KW - Population studies KW - Children KW - Public health KW - Data banks KW - Multivariate analysis KW - Geriatrics KW - Traumatic brain injury KW - Hospitals KW - W 30960:Bioinformatics & Computer Applications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1855073181?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Injury+Epidemiology&rft.atitle=Outcomes+of+pediatric+severe+traumatic+brain+injury+patients+treated+in+adult+trauma+centers+with+and+without+added+qualifications+in+pediatrics+-+United+States%2C+2009&rft.au=Ovalle%2C+Fernando%3BXu%2C+Likang%3BPearson%2C+William+S%3BSpelke%2C+Bridget%3BSugerman%2C+David+E&rft.aulast=Ovalle&rft.aufirst=Fernando&rft.date=2014-12-01&rft.volume=1&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Injury+Epidemiology&rft.issn=2197-1714&rft_id=info:doi/10.1186%2F2197-1714-1-15 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2017-01-01 N1 - Number of references - 39 N1 - Last updated - 2017-01-18 N1 - SubjectsTermNotLitGenreText - Mortality; Age; Head; Injuries; Pediatrics; Population studies; Survival; Children; Public health; Data banks; Multivariate analysis; Geriatrics; Traumatic brain injury; Hospitals DO - http://dx.doi.org/10.1186/2197-1714-1-15 ER - TY - JOUR T1 - Co-Infection of Rickettsia rickettsii and Streptococcus pyogenes: Is Fatal Rocky Mountain Spotted Fever Underdiagnosed? AN - 1727697583; PQ0002140042 AB - Rocky Mountain spotted fever, a tick-borne disease caused by Rickettsia rickettsii, is challenging to diagnose and rapidly fatal if not treated. We describe a decedent who was co-infected with group A [beta]-hemolytic streptococcus and R. rickettsii. Fatal cases of Rocky Mountain spotted fever may be underreported because they present as difficult to diagnose co-infections. JF - American Journal of Tropical Medicine and Hygiene AU - Raczniak, Gregory A AU - Kato, Cecilia AU - Chung, Ida H AU - Austin, Amy AU - McQuiston, Jennifer H AU - Weis, Erica AU - Levy, Craig AU - Carvalho, Maria da Gloria S AU - Mitchell, Audrey AU - Bjork, Adam AU - Regan, Joanna J AD - Epidemic Intelligence Service, Center for Surveillance, Epidemiology and Laboratory Services, Rickettsial Zoonoses Branch, National Center for Emerging and Zoonotic Infectious Diseases, Streptococcus Laboratory, National Center for Immunization and Respiratory Diseases, HIV Prevention Branch, Division of Global HIV/AIDS, Center for Global Health, Border Health Services Branch, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, vih5@cdc.gov Y1 - 2014/12// PY - 2014 DA - December 2014 SP - 1154 EP - 1155 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 91 IS - 6 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - North America, Rocky Mts. KW - Rocky Mountain spotted fever KW - tick-borne diseases KW - Rickettsia rickettsii KW - Hygiene KW - Streptococcus pyogenes KW - K 03490:Miscellaneous KW - Q1 08484:Species interactions: parasites and diseases KW - J 02400:Human Diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727697583?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Co-Infection+of+Rickettsia+rickettsii+and+Streptococcus+pyogenes%3A+Is+Fatal+Rocky+Mountain+Spotted+Fever+Underdiagnosed%3F&rft.au=Raczniak%2C+Gregory+A%3BKato%2C+Cecilia%3BChung%2C+Ida+H%3BAustin%2C+Amy%3BMcQuiston%2C+Jennifer+H%3BWeis%2C+Erica%3BLevy%2C+Craig%3BCarvalho%2C+Maria+da+Gloria+S%3BMitchell%2C+Audrey%3BBjork%2C+Adam%3BRegan%2C+Joanna+J&rft.aulast=Raczniak&rft.aufirst=Gregory&rft.date=2014-12-01&rft.volume=91&rft.issue=6&rft.spage=1154&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0437 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Hygiene; Rocky Mountain spotted fever; tick-borne diseases; Rickettsia rickettsii; Streptococcus pyogenes; North America, Rocky Mts. DO - http://dx.doi.org/10.4269/ajtmh.14-0437 ER - TY - JOUR T1 - Integrating active tuberculosis case finding in antenatal services in Zambia AN - 1654680496; 21194774 AB - SETTING: Three out-patient antenatal care (ANC) clinics in Lusaka, Zambia. OBJECTIVE: To estimate tuberculosis (TB) prevalence in human immunodeficiency virus (HIV) infected and symptomatic, non-HIV-infected pregnant women and explore the feasibility of routine TB screening in ANC settings. DESIGN: Peer educators administered TB symptom questionnaires to pregnant women attending their first ANC clinic visit. Presumptive TB patients were defined as all HTV-infected women and symptomatic non-HIV-infected women. Sputum samples were tested using smear microscopy and culture to estimate TB prevalence. RESULTS: All 5033 (100%) women invited to participate in the study agreed, and 17% reported one or more TB symptoms. Among 1152 presumed TB patients, 17 (1.5%) had previously undiagnosed culture-confirmed TB; 2 (12%) were smear-positive. Stratified by HIV status, TB prevalence was 10/664 (1.5%, 95%CI 0.7-2.8) among HIV-infected women and 7/488 (1.4%, 95%CI 0.6-2.9) among symptomatic non-HIV-infected women. In HIV-infected women, the only symptom significantly associated with TB was productive cough; symptom screening was only 50% sensitive. CONCLUSION: There is a sizable burden of TB in pregnant women in Zambia, which may lead to adverse maternal and infant outcomes. TB screening in ANC settings in Zambia is acceptable and feasible. More sensitive diagnostics are needed. JF - International Journal of Tuberculosis and Lung Disease AU - Kancheya, N AU - Luhanga, D AU - Harris, J B AU - Morse, J AU - Kapata, N AU - Bweupe, M AU - Henostroza, G AU - Reid, S E AD - Centre for Infectious Disease Research in Zambia, Lusaka, Zambia; Centers for Disease Control and Prevention (CDC), 351 Independence Avenue, US Embassy/CDC, PO Box 31617, Lusaka, Zambia, yde3@cdc.gov Y1 - 2014/12// PY - 2014 DA - Dec 2014 SP - 1466 EP - 1472 PB - International Union Against Tuberculosis and Lung Disease, 68 bvd Saint-Michel Paris 75006 France VL - 18 IS - 12 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology KW - pregnancy KW - tuberculosis screening KW - ante-natal clinics KW - Zambia KW - Inventories KW - Human immunodeficiency virus KW - Mycobacterium KW - Microscopy KW - Lung diseases KW - Cough KW - Tuberculosis KW - Sputum KW - Pregnancy KW - Infants KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1654680496?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Integrating+active+tuberculosis+case+finding+in+antenatal+services+in+Zambia&rft.au=Kancheya%2C+N%3BLuhanga%2C+D%3BHarris%2C+J+B%3BMorse%2C+J%3BKapata%2C+N%3BBweupe%2C+M%3BHenostroza%2C+G%3BReid%2C+S+E&rft.aulast=Kancheya&rft.aufirst=N&rft.date=2014-12-01&rft.volume=18&rft.issue=12&rft.spage=1466&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/10.5588%2Fijtld.14.0920 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-02-01 N1 - Last updated - 2015-04-16 N1 - SubjectsTermNotLitGenreText - Inventories; Microscopy; Lung diseases; Cough; Tuberculosis; Sputum; Infants; Pregnancy; Mycobacterium; Human immunodeficiency virus DO - http://dx.doi.org/10.5588/ijtld.14.0920 ER - TY - JOUR T1 - Bedbug Complaints among Public Housing Residents-New York City, 2010-2011 AN - 1642626443; 21151059 AB - Few studies have evaluated population-level risk factors for having a bedbug infestation. We describe characteristics associated with bedbug complaints among New York City Housing Authority (NYCHA) residents. Unique households receiving bedbug extermination services in response to a complaint during January 1, 2010 to December 31, 2011 were identified from NYCHA's central facilities work order database. We examined associations between household characteristics and having a bedbug complaint using a generalized estimating equation Poisson regression model, accounting for clustering by housing development. Of the 176,327 NYCHA households, 11,660 (6.6 %) registered a bedbug complaint during 2010-2011. Bedbug complaints were independently associated with households having five or more children versus no children (prevalence ratio [PR]=2.0), five or more adults versus one adult (PR=1.6), a head of household (HOH) with impaired mobility (PR=1.3), a household member receiving public assistance (PR=1.2), a household income below poverty level (PR=1.1), and a female HOH (PR=1.1). Infestations were less likely to be reported by households with employed members (PR=0.9), and an HOH aged 30-44 years (PR=0.9) or 45-61 years (PR=0.9), compared with an HOH aged 18-29 years. These results indicate that bedbug control efforts in public housing should be targeted toward households with low income and high occupancy. JF - Journal of Urban Health AU - Gounder, Prabhu AU - Ralph, Nancy AU - Maroko, Andrew AU - Thorpe, Lorna AD - Arctic Investigations Program, Centers for Disease Control and Prevention, Anchorage, AK, USA, iym4@cdc.gov Y1 - 2014/12// PY - 2014 DA - Dec 2014 SP - 1076 EP - 1086 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 91 IS - 6 SN - 1099-3460, 1099-3460 KW - Risk Abstracts; Health & Safety Science Abstracts KW - USA, New York, New York City KW - Housing developments KW - Housing KW - Mobility KW - Households KW - Risk factors KW - Poverty KW - Children KW - Income KW - Urban areas KW - H 0500:General KW - R2 23070:Economics, organization UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1642626443?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Urban+Health&rft.atitle=Bedbug+Complaints+among+Public+Housing+Residents-New+York+City%2C+2010-2011&rft.au=Gounder%2C+Prabhu%3BRalph%2C+Nancy%3BMaroko%2C+Andrew%3BThorpe%2C+Lorna&rft.aulast=Gounder&rft.aufirst=Prabhu&rft.date=2014-12-01&rft.volume=91&rft.issue=6&rft.spage=1076&rft.isbn=&rft.btitle=&rft.title=Journal+of+Urban+Health&rft.issn=10993460&rft_id=info:doi/10.1007%2Fs11524-013-9859-y LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Number of references - 28 N1 - Last updated - 2015-02-18 N1 - SubjectsTermNotLitGenreText - Housing developments; Mobility; Housing; Poverty; Risk factors; Households; Children; Urban areas; Income; USA, New York, New York City DO - http://dx.doi.org/10.1007/s11524-013-9859-y ER - TY - JOUR T1 - pncA and bptA Are Not Sufficient To Complement Ixodes scapularis Colonization and Persistence by Borrelia burgdorferi in a Linear Plasmid lp25-Deficient Background AN - 1642614142; 21154669 AB - The complex segmented genome of Borrelia burgdorferi is comprised of a linear chromosome along with numerous linear and circular plasmids essential for tick and/or mammalian infectivity. The pathogenic necessity for specific borrelial plasmids has been identified; most notably, infections of the tick vector and mammalian host both require linear plasmid 25 (lp25). Genes carried on lp25, specifically bptA and pncA, are postulated to play a role for B. burgdorferi to infect and persist in Ixodes ticks. In this study, we complemented an lp25-deficient borrelial strain with pncA alone or pncA accompanied by bptA to evaluate the ability of the complemented strains to restore larval colonization and persistence through transstadial transmission relative to that of wild-type B. burgdorferi. The acquisition of the complemented strains by tick larvae from infected mice and/or the survival of these strains was significantly decreased when assayed by cultivation and quantitative PCR (qPCR). Only 10% of the pncA-complemented strain organisms were found by culture to survive 17 days following larval feeding, while 45% of the pncA- and bptA-complemented strain organisms survived, with similar results by PCR. However, neither of the complemented B. burgdorferi strains was capable of persisting through the molt to the nymphal stage as analyzed by culture. qPCR analyses of unfed nymphs detected B. burgdorferi genomes in several nymphs at low copy numbers, likely indicating the presence of DNA from dead or dying cells. Overall, the data indicate that pncA and bptA cannot independently support infection, suggesting that lp25 carries additional gene(s) or regulatory elements critical for B. burgdorferi survival and pathogenesis in the Ixodes vector. JF - Infection and Immunity AU - Gilmore, Robert D AU - Brandt, Kevin S AU - Hyde, Jenny A AD - National Center for Emerging and Zoonotic Infectious Diseases, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado, USA, jshyde@medicine.tamhsc.edu. Y1 - 2014/12// PY - 2014 DA - Dec 2014 SP - 5110 EP - 5116 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 82 IS - 12 SN - 0019-9567, 0019-9567 KW - Entomology Abstracts; Genetics Abstracts; Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Ixodes KW - Genomes KW - Feeding KW - Data processing KW - Borrelia burgdorferi KW - Ixodidae KW - Regulatory sequences KW - Larvae KW - Survival KW - Vectors KW - Cell culture KW - Ixodes scapularis KW - Molting KW - Infection KW - Plasmids KW - copy number KW - Disease transmission KW - Colonization KW - Chromosomes KW - Infectivity KW - Polymerase chain reaction KW - Z 05360:Genetics and Evolution KW - J 02350:Immunology KW - F 06910:Microorganisms & Parasites KW - G 07770:Bacteria UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1642614142?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Infection+and+Immunity&rft.atitle=pncA+and+bptA+Are+Not+Sufficient+To+Complement+Ixodes+scapularis+Colonization+and+Persistence+by+Borrelia+burgdorferi+in+a+Linear+Plasmid+lp25-Deficient+Background&rft.au=Gilmore%2C+Robert+D%3BBrandt%2C+Kevin+S%3BHyde%2C+Jenny+A&rft.aulast=Gilmore&rft.aufirst=Robert&rft.date=2014-12-01&rft.volume=82&rft.issue=12&rft.spage=5110&rft.isbn=&rft.btitle=&rft.title=Infection+and+Immunity&rft.issn=00199567&rft_id=info:doi/10.1128%2FIAI.02613-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Number of references - 44 N1 - Last updated - 2015-04-02 N1 - SubjectsTermNotLitGenreText - Genomes; Feeding; Data processing; Regulatory sequences; Larvae; Vectors; Survival; Cell culture; Plasmids; Infection; Molting; Disease transmission; copy number; Colonization; Infectivity; Chromosomes; Polymerase chain reaction; Ixodes; Borrelia burgdorferi; Ixodidae; Ixodes scapularis DO - http://dx.doi.org/10.1128/IAI.02613-14 ER - TY - JOUR T1 - Complications of cesarean deliveries among HIV-infected women in the United States AN - 1765971965; PQ0002559503 AB - Objective: To compare rates of complications associated with cesarean delivery in HIV-infected and HIV-uninfected women in the United States and to investigate trends in such complications across four study cycles spanning the implementation of HAART in the United States (1995-1996, 2000-2001, 2005-2006, 2010-2011). Design: The Nationwide Inpatient Sample from the Healthcare Cost and Utilization Project is the largest all-payer hospital inpatient care database in the United States; when weighted to account for the complex sampling design, nationally representative estimates are derived. After restricting the study sample to women aged 15-49 years, our study sample consisted of approximately 1 090 000 cesarean delivery hospitalizations annually. Methods: Complications associated with cesarean deliveries were categorized as infection, hemorrhage, or surgical trauma, based on groups of specific International Classification of Diseases 9th revision codes. Length of hospitalization, hospital charges, and in-hospital deaths were also examined. Results: The rate of complications significantly decreased during the study periods for HIV-infected and HIV-uninfected women. However, rates of infectious complications and surgical trauma associated with cesarean deliveries remained higher among HIV-infected, compared with HIV-uninfected women in 2010-2011, as did prolonged hospital stay and in-hospital deaths. Length of hospitalization decreased over time for cesarean deliveries of HIV-infected women to a greater extent compared with HIV-uninfected women. Conclusion: In the United States, rates of cesarean delivery complications decreased from 1995 to 2011. However, rates of infection, surgical trauma, hospital deaths, and prolonged hospitalization are still higher among HIV-infected women. Clinicians should remain alert to this persistently increased risk of cesarean delivery complications among HIV-infected women. JF - AIDS AU - Kourtis, Athena P AU - Ellington, Sascha AU - Pazol, Karen AU - Flowers, Lisa AU - Haddad, Lisa AU - Jamieson, Denise J AD - Women's Health and Fertility Branch, Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, apk3@cdc.gov Y1 - 2014/11/13/ PY - 2014 DA - 2014 Nov 13 SP - 2609 EP - 2618 PB - Lippincott Williams & Wilkins, Inc, 530 Walnut Street Philadelphia PA 19106-3621 United States VL - 28 IS - 17 SN - 0269-9370, 0269-9370 KW - Health & Safety Science Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - AIDS KW - cesarean section KW - HAART KW - HIV KW - obstetric labor complications KW - Mortality KW - Acquired immune deficiency syndrome KW - Complications KW - Infection KW - Hemorrhage KW - Trauma KW - Databases KW - USA KW - Health care KW - Classification KW - Human immunodeficiency virus KW - highly active antiretroviral therapy KW - Surgery KW - Cesarean section KW - Females KW - Sampling KW - Hospitals KW - V 22360:AIDS and HIV KW - H 13000:Medical Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1765971965?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS&rft.atitle=Complications+of+cesarean+deliveries+among+HIV-infected+women+in+the+United+States&rft.au=Kourtis%2C+Athena+P%3BEllington%2C+Sascha%3BPazol%2C+Karen%3BFlowers%2C+Lisa%3BHaddad%2C+Lisa%3BJamieson%2C+Denise+J&rft.aulast=Kourtis&rft.aufirst=Athena&rft.date=2014-11-13&rft.volume=28&rft.issue=17&rft.spage=2609&rft.isbn=&rft.btitle=&rft.title=AIDS&rft.issn=02699370&rft_id=info:doi/10.1097%2FQAD.0000000000000474 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Databases; Classification; highly active antiretroviral therapy; Cesarean section; Sampling; Hemorrhage; Infection; Trauma; Hospitals; Mortality; Acquired immune deficiency syndrome; Health care; Complications; Surgery; Females; Human immunodeficiency virus; USA DO - http://dx.doi.org/10.1097/QAD.0000000000000474 ER - TY - JOUR T1 - Narcolepsy and influenza A(H1N1) pandemic 2009 vaccination in the United States AN - 1687672295; PQ0001546665 AB - Objective: To assess the occurrence of narcolepsy after influenza vaccines used in the United States that contained the influenza A(H1N1)pdm09 virus strain. Methods: A population-based cohort study in the Vaccine Safety Datalink with an annual population of more than 8.5 million people. All persons younger than 30 years who received a 2009 pandemic or a 2010-2011 seasonal influenza vaccine were identified. Their medical visit history was searched for a first-ever occurrence of an ICD-9 narcolepsy diagnosis code through the end of 2011. Chart review was done to confirm the diagnosis and determine the date of symptom onset. Cases were patients who met the International Classification of Sleep Disorders, 2nd edition, narcolepsy diagnostic criteria. We compared the observed number of cases after vaccination to the number expected to occur by chance alone. Results: The number vaccinated with 2009 pandemic vaccine was 650,995 and with 2010-2011 seasonal vaccine was 870,530. Among these patients, 70 had a first-ever narcolepsy diagnosis code after vaccination, of which 16 had a chart-confirmed incident diagnosis of narcolepsy. None had their symptom onset during the 180 days after receipt of a 2009 pandemic vaccine compared with 6.52 expected, and 2 had onset after a 2010-2011 seasonal vaccine compared with 8.83 expected. Conclusions: Influenza vaccines containing the A(H1N1)pdm09 virus strain used in the United States were not associated with an increased risk of narcolepsy. Vaccination with the influenza A(H1N1)pdm09 vaccine viral antigens does not appear to be sufficient by itself to increase the incidence of narcolepsy in a population. JF - Neurology AU - Duffy, Jonathan AU - Weintraub, Eric AU - Vellozzi, Claudia AU - DeStefano, Frank AD - Immunization Safety Office, Centers for Disease Control and Prevention, Atlanta, GA, jduffy@cdc.gov Y1 - 2014/11/11/ PY - 2014 DA - 2014 Nov 11 SP - 1823 EP - 1830 PB - Lippincott Williams & Wilkins, 16522 Hunters Green Parkway Hagerstown MD 21740-2116 United States VL - 83 IS - 20 SN - 0028-3878, 0028-3878 KW - Risk Abstracts; Health & Safety Science Abstracts; Virology & AIDS Abstracts; CSA Neurosciences Abstracts KW - Risk assessment KW - Historical account KW - Sleep disorders KW - Safety KW - Influenza KW - USA KW - pandemics KW - Sulfur dioxide KW - Classification KW - Narcolepsy KW - Reviews KW - Vaccines KW - Seasonal variations KW - R2 23060:Medical and environmental health KW - N3 11027:Neurology & neuropathology KW - H 4000:Food and Drugs KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1687672295?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurology&rft.atitle=Narcolepsy+and+influenza+A%28H1N1%29+pandemic+2009+vaccination+in+the+United+States&rft.au=Duffy%2C+Jonathan%3BWeintraub%2C+Eric%3BVellozzi%2C+Claudia%3BDeStefano%2C+Frank&rft.aulast=Duffy&rft.aufirst=Jonathan&rft.date=2014-11-11&rft.volume=83&rft.issue=20&rft.spage=1823&rft.isbn=&rft.btitle=&rft.title=Neurology&rft.issn=00283878&rft_id=info:doi/10.1212%2FWNL.0000000000000987 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-06-01 N1 - Last updated - 2015-08-19 N1 - SubjectsTermNotLitGenreText - Influenza; pandemics; Classification; Sleep disorders; Narcolepsy; Vaccines; Risk assessment; Historical account; Sulfur dioxide; Reviews; Safety; Seasonal variations; USA DO - http://dx.doi.org/10.1212/WNL.0000000000000987 ER - TY - JOUR T1 - Primary prevention of lead poisoning in children: a cross-sectional study to evaluate state specific lead-based paint risk reduction laws in preventing lead poisoning in children. AN - 1627071895; 25380793 AB - Children younger than 72 months are most at risk of environmental exposure to lead from ingestion through normal mouthing behavior. Young children are more vulnerable to lead poisoning than adults because lead is absorbed more readily in a child's gastrointestinal tract. Our focus in this study was to determine the extent to which state mandated lead laws have helped decrease the number of new cases of elevated blood-lead levels (EBLL) in homes where an index case had been identified. A cross-sectional study was conducted to compare 682 residential addresses, identified between 2000 and 2009, in two states with and one state without laws to prevent childhood lead poisoning among children younger than 72 months, to determine whether the laws were effective in preventing subsequent cases of lead poisoning detected in residential addresses after the identification of an index case. In this study, childhood lead poisoning was defined as the blood lead level (BLL) that would have triggered an environmental investigation in the residence. The two states with lead laws, Massachusetts (MA) and Ohio (OH), had trigger levels of ≥25 μg/dL and ≥15 μg/dL respectively. In Mississippi (MS), the state without legislation, the trigger level was ≥15 μg/dL. The two states with lead laws, MA and OH, were 79% less likely than the one without legislation, MS, to have residential addresses with subsequent lead poisoning cases among children younger than 72 months, adjusted OR = 0.21, 95% CI (0.08-0.54). For the three states studied, the evidence suggests that lead laws such as those studied herein effectively reduced primary exposure to lead among young children living in residential addresses that may have had lead contaminants. JF - Environmental health : a global access science source AU - Kennedy, Chinaro AU - Lordo, Robert AU - Sucosky, Marissa Scalia AU - Boehm, Rona AU - Brown, Mary Jean AD - Centers for Disease Control and Prevention, National Center for Environmental Health/Agency for Toxic Substances and Disease Registry, 4770 Buford Highway, Atlanta, GA 30341, USA. gjn5@cdc.gov. Y1 - 2014/11/07/ PY - 2014 DA - 2014 Nov 07 SP - 93 VL - 13 KW - Index Medicus KW - Infant KW - Cross-Sectional Studies KW - Housing KW - Massachusetts KW - Humans KW - Mississippi KW - Infant, Newborn KW - Male KW - Female KW - Ohio KW - Child, Preschool KW - Lead Poisoning -- prevention & control KW - Primary Prevention -- legislation & jurisprudence KW - Environmental Exposure -- legislation & jurisprudence KW - Paint -- poisoning KW - Environmental Exposure -- prevention & control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1627071895?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+health+%3A+a+global+access+science+source&rft.atitle=Primary+prevention+of+lead+poisoning+in+children%3A+a+cross-sectional+study+to+evaluate+state+specific+lead-based+paint+risk+reduction+laws+in+preventing+lead+poisoning+in+children.&rft.au=Kennedy%2C+Chinaro%3BLordo%2C+Robert%3BSucosky%2C+Marissa+Scalia%3BBoehm%2C+Rona%3BBrown%2C+Mary+Jean&rft.aulast=Kennedy&rft.aufirst=Chinaro&rft.date=2014-11-07&rft.volume=13&rft.issue=&rft.spage=93&rft.isbn=&rft.btitle=&rft.title=Environmental+health+%3A+a+global+access+science+source&rft.issn=1476-069X&rft_id=info:doi/10.1186%2F1476-069X-13-93 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2015-03-04 N1 - Date created - 2014-11-21 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Cited By: Am J Public Health. 2001 Apr;91(4):621-4 [11291376] Public Health Rep. 2000 Nov-Dec;115(6):521-9 [11354334] WMJ. 2001;100(8):48-54 [12685297] N Engl J Med. 2003 Apr 17;348(16):1517-26 [12700371] Arch Environ Health. 1980 Jan-Feb;35(1):53-8 [7362271] MMWR Morb Mortal Wkly Rep. 1985 Feb 8;34(5):66-8, 73 [2982087] J Health Polit Policy Law. 2013 Aug;38(4):757-813 [23645870] Pediatrics. 1996 Jul;98(1):35-40 [8668409] Environ Health Perspect. 2005 Jul;113(7):894-9 [16002379] Pediatrics. 2006 Jan;117(1):147-53 [16396872] Environ Health Perspect. 2008 Feb;116(2):243-8 [18288325] MMWR Morb Mortal Wkly Rep. 2009 Jan 30;58(3):55-8 [19177040] Public Health Rep. 2011 May-Jun;126 Suppl 1:76-88 [21563715] N Engl J Med. 1990 Jan 11;322(2):83-8 [2294437] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1186/1476-069X-13-93 ER - TY - JOUR T1 - Prevalence of Strongyloides stercoralis Antibodies among a Rural Appalachian Population-Kentucky, 2013 AN - 1722180406; PQ0002099262 AB - We investigated whether Strongyloides infection remains endemic in rural Kentucky's Appalachian regions; 7 of 378 (1.9%) participants tested positive for Strongyloides antibodies. We identified no statistically significant association between a positive test and travel to a known endemic country (P = 0.58), indicating that transmission in rural Kentucky might be ongoing. Disclaimer: The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention. JF - American Journal of Tropical Medicine and Hygiene AU - Russell, Elizabeth S AU - Gray, Elizabeth B AU - Marshall, Rebekah E AU - Davis, Stephanie AU - Beaudoin, Amanda AU - Handali, Sukwan AU - McAuliffe, Isabel AU - Davis, Cheryl AU - Woodhall, Dana AD - Kentucky Department for Public Health, Frankfort, Kentucky, EBGray@cdc.gov Y1 - 2014/11// PY - 2014 DA - November 2014 SP - 1000 EP - 1001 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 91 IS - 5 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Travel KW - Statistical analysis KW - Disease control KW - Infection KW - Strongyloides KW - Antibodies KW - Endemic species KW - USA, Kentucky KW - Strongyloides stercoralis KW - Hygiene KW - K 03300:Methods KW - Q1 08604:Stock assessment and management KW - Q5 08524:Public health, medicines, dangerous organisms KW - J 02300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1722180406?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Prevalence+of+Strongyloides+stercoralis+Antibodies+among+a+Rural+Appalachian+Population-Kentucky%2C+2013&rft.au=Russell%2C+Elizabeth+S%3BGray%2C+Elizabeth+B%3BMarshall%2C+Rebekah+E%3BDavis%2C+Stephanie%3BBeaudoin%2C+Amanda%3BHandali%2C+Sukwan%3BMcAuliffe%2C+Isabel%3BDavis%2C+Cheryl%3BWoodhall%2C+Dana&rft.aulast=Russell&rft.aufirst=Elizabeth&rft.date=2014-11-01&rft.volume=91&rft.issue=5&rft.spage=1000&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0310 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Endemic species; Antibodies; Disease control; Hygiene; Travel; Statistical analysis; Infection; Strongyloides; Strongyloides stercoralis; USA, Kentucky DO - http://dx.doi.org/10.4269/ajtmh.14-0310 ER - TY - JOUR T1 - Soil-Transmitted Helminths in Pre-School-Aged and School-Aged Children in an Urban Slum: A Cross-Sectional Study of Prevalence, Distribution, and Associated Exposures AN - 1722172947; PQ0002099263 AB - Soil-transmitted helminths (STHs) are controlled by regular mass drug administration. Current practice targets school-age children (SAC) preferentially over pre-school age children (PSAC) and treats large areas as having uniform prevalence. We assessed infection prevalence in SAC and PSAC and spatial infection heterogeneity, using a cross-sectional study in two slum villages in Kibera, Nairobi. Nairobi has low reported STH prevalence. The SAC and PSAC were randomly selected from the International Emerging Infections Program's surveillance platform. Data included residence location and three stools tested by Kato-Katz for STHs. Prevalences among 692 analyzable children were any STH: PSAC 40.5%, SAC 40.7%; Ascaris: PSAC 24.1%, SAC 22.7%; Trichuris: PSAC 24.0%, SAC 28.8%; hookworm < 0.1%. The STH infection prevalence ranged from 22% to 71% between sub-village sectors. The PSAC have similar STH prevalences to SAC and should receive deworming. Small areas can contain heterogeneous prevalences; determinants of STH infection should be characterized and slums should be assessed separately in STH mapping. JF - American Journal of Tropical Medicine and Hygiene AU - Davis, Stephanie M AU - Worrell, Caitlin M AU - Wiegand, Ryan E AU - Odero, Kennedy O AU - Suchdev, Parminder S AU - Ruth, Laird J AU - Lopez, Gerard AU - Cosmas, Leonard AU - Neatherlin, John AU - Njenga, Sammy M AU - Montgomery, Joel M AU - Fox, LeAnne M AD - Parasitic Diseases Branch, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, Vic6@cdc.gov Y1 - 2014/11// PY - 2014 DA - November 2014 SP - 1002 EP - 1010 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 91 IS - 5 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Age KW - Data processing KW - Surveillance and enforcement KW - Kenya, Nairobi KW - Infection KW - Children KW - Ascaris KW - Mapping KW - Feces KW - Hygiene KW - Drugs KW - K 03400:Human Diseases KW - J 02400:Human Diseases KW - Q1 08604:Stock assessment and management KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1722172947?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Soil-Transmitted+Helminths+in+Pre-School-Aged+and+School-Aged+Children+in+an+Urban+Slum%3A+A+Cross-Sectional+Study+of+Prevalence%2C+Distribution%2C+and+Associated+Exposures&rft.au=Davis%2C+Stephanie+M%3BWorrell%2C+Caitlin+M%3BWiegand%2C+Ryan+E%3BOdero%2C+Kennedy+O%3BSuchdev%2C+Parminder+S%3BRuth%2C+Laird+J%3BLopez%2C+Gerard%3BCosmas%2C+Leonard%3BNeatherlin%2C+John%3BNjenga%2C+Sammy+M%3BMontgomery%2C+Joel+M%3BFox%2C+LeAnne+M&rft.aulast=Davis&rft.aufirst=Stephanie&rft.date=2014-11-01&rft.volume=91&rft.issue=5&rft.spage=1002&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0060 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Surveillance and enforcement; Hygiene; Drugs; Age; Data processing; Mapping; Feces; Children; Infection; Ascaris; Kenya, Nairobi DO - http://dx.doi.org/10.4269/ajtmh.14-0060 ER - TY - JOUR T1 - Viability of Leptospira Isolates from a Human Outbreak in Thailand in Various Water Types, pH, and Temperature Conditions AN - 1722169725; PQ0002099266 AB - Leptospira spp. isolated from patients during a multiyear outbreak in Thailand were genotyped using multilocus sequence typing and a majority were identified as ST34, especially in earlier years. We tested whether ST34 isolates were better adapted to survive in various pH levels, temperatures, and water sources. Motility and growth were monitored over a 1 2-week period. Early year ST34 isolates did not appear to have a significant fitness advantage over non-ST34, however, this may have been because a majority of the isolates survived to the termination of the study, with the exception being at high temperature (37[degrees]C) and/or basic pH (8.65). Failure to detect a significant fitness advantage of ST34 may be a result of the length of the study or the small sample size. Lengthening the study and looking at virulence and maintenance in the host could yield additional information about this outbreak. JF - American Journal of Tropical Medicine and Hygiene AU - Stoddard, Robyn A AU - Bui, Duy AU - Haberling, Dana L AU - Wuthiekanun, Vanaporn AU - Thaipadungpanit, Janjira AU - Hoffmaster, Alex R AD - Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, Georgia, RAStoddard@cdc.gov Y1 - 2014/11// PY - 2014 DA - November 2014 SP - 1020 EP - 1022 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 91 IS - 5 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Fitness KW - Temperature effects KW - Leptospira KW - Water temperature KW - multilocus sequence typing KW - Virulence KW - Motility KW - Growth KW - ISEW, Thailand KW - Hygiene KW - pH effects KW - pH KW - Q1 08484:Species interactions: parasites and diseases KW - J 02400:Human Diseases KW - Q5 08524:Public health, medicines, dangerous organisms KW - K 03320:Cell Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1722169725?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Viability+of+Leptospira+Isolates+from+a+Human+Outbreak+in+Thailand+in+Various+Water+Types%2C+pH%2C+and+Temperature+Conditions&rft.au=Stoddard%2C+Robyn+A%3BBui%2C+Duy%3BHaberling%2C+Dana+L%3BWuthiekanun%2C+Vanaporn%3BThaipadungpanit%2C+Janjira%3BHoffmaster%2C+Alex+R&rft.aulast=Stoddard&rft.aufirst=Robyn&rft.date=2014-11-01&rft.volume=91&rft.issue=5&rft.spage=1020&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.13-0748 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Temperature effects; Virulence; Growth; Hygiene; pH; Fitness; Motility; Water temperature; pH effects; multilocus sequence typing; Leptospira; ISEW, Thailand DO - http://dx.doi.org/10.4269/ajtmh.13-0748 ER - TY - JOUR T1 - Vaccine-Derived Polioviruses AN - 1687678188; PQ0001574039 AB - The attenuated oral poliovirus vaccine (OPV) has many properties favoring its use in polio eradication: ease of administration, efficient induction of intestinal immunity, induction of durable humoral immunity, and low cost. Despite these advantages, OPV has the disadvantage of genetic instability, resulting in rare and sporadic cases of vaccine-associated paralytic poliomyelitis (VAPP) and the emergence of genetically divergent vaccine-derived polioviruses (VDPVs). Whereas VAPP is an adverse event following exposure to OPV, VDPVs are polioviruses whose genetic properties indicate prolonged replication or transmission. Three categories of VDPVs are recognized: (1) circulating VDPVs (cVDPVs) from outbreaks in settings of low OPV coverage, (2) immunodeficiency-associated VDPVs (iVDPVs) from individuals with primary immunodeficiencies, and (3) ambiguous VDPVs (aVDPVs), which cannot be definitively assigned to either of the first 2 categories. Because most VDPVs are type 2, the World Health Organization's plans call for coordinated worldwide replacement of trivalent OPV with bivalent OPV containing poliovirus types 1 and 3. JF - Journal of Infectious Diseases AU - Burns, Cara C AU - Diop, Ousmane M AU - Sutter, Roland W AU - Kew, Olen M AD - Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, cburns@cdc.gov Y1 - 2014/11/01/ PY - 2014 DA - 2014 Nov 01 SP - S283 EP - S293 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 210 SN - 0022-1899, 0022-1899 KW - Health & Safety Science Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - poliovirus KW - vaccine-derived poliovirus KW - VDPV KW - oral poliovirus vaccine KW - OPV KW - poliomyelitis KW - Poliovirus KW - Replication KW - Immunodeficiency KW - vaccine-associated paralytic poliomyelitis KW - Disease transmission KW - Immunity (humoral) KW - Infectious diseases KW - Intestine KW - Outbreaks KW - Vaccines KW - Side effects KW - V 22320:Replication KW - F 06910:Microorganisms & Parasites KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1687678188?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Vaccine-Derived+Polioviruses&rft.au=Burns%2C+Cara+C%3BDiop%2C+Ousmane+M%3BSutter%2C+Roland+W%3BKew%2C+Olen+M&rft.aulast=Burns&rft.aufirst=Cara&rft.date=2014-11-01&rft.volume=210&rft.issue=&rft.spage=S283&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiu295 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-06-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Immunity (humoral); Replication; Immunodeficiency; Intestine; Vaccines; vaccine-associated paralytic poliomyelitis; Disease transmission; Poliovirus; Infectious diseases; Outbreaks; Side effects DO - http://dx.doi.org/10.1093/infdis/jiu295 ER - TY - JOUR T1 - Post-licensure surveillance of trivalent live attenuated influenza vaccine in adults, United States, Vaccine Adverse Event Reporting System (VAERS), July 2005-June 2013 AN - 1664206158; PQ0001196985 AB - Background Trivalent live attenuated influenza vaccine (LAIV3) was licensed and recommended for use in 2003 in children and adults 2-49 years of age. Post-licensure safety data have been limited, particularly in adults. Methods We searched Vaccine Adverse Event Reporting System (VAERS) for US reports after LAIV3 from July 1, 2005-June 30, 2013 (eight influenza seasons) in adults aged greater than or equal to 18 years old. We conducted descriptive analyses and clinically reviewed serious reports (i.e., death, life-threatening illness, hospitalization, prolonged hospitalization, or permanent disability) and reports of selected conditions of interest. We used empirical Bayesian data mining to identify adverse events (AEs) that were reported more frequently than expected. We calculated crude AE reporting rates to VAERS by influenza season. Results During the study period, VAERS received 1207 LAIV3 reports in adults aged 18-49 years old; 107 (8.9%) were serious, including four death reports. The most commonly reported events were expired drug administered (n=207, 17%), headache (n=192, 16%), and fever (n=133, 11%). The most common diagnostic categories for non-fatal serious reports were neurological (n=40, 39%), cardiovascular (n=14, 14%), and other non-infectious conditions (n=20, 19%). We noted a higher proportion of Guillain-Barre syndrome (GBS) and cardiovascular reports in the Department of Defense (DoD) population compared to the civilian population. Data mining detected disproportional reporting of ataxia (n=15); clinical review revealed that ataxia was a component of diverse clinical entities including GBS. Conclusions Review of VAERS reports are reassuring, the only unexpected safety concern for LAIV3 identified was a higher than expected number of GBS reports in the DoD population, which is being investigated. Reports of administration of expired LAIV3 represent administration errors and indicate the need for education, training and screening regarding the approved indications. JF - Vaccine AU - Haber, Penina AU - Moro, Pedro L AU - McNeil, Michael M AU - Lewis, Paige AU - Woo, Emily Jane AU - Hughes, Hayley AU - Shimabukuro, Tom T AD - Immunization Safety Office, Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), Centers for Disease Control and Prevention (CDC), 1600 Clifton Rd NE, Atlanta, GA 30333, USA Y1 - 2014/11// PY - 2014 DA - Nov 2014 SP - 6499 EP - 6504 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 32 IS - 48 SN - 0264-410X, 0264-410X KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts; Immunology Abstracts KW - Vaccine safety KW - Post-licensure surveillance KW - Live attenuated influenza vaccine KW - Age KW - Bayesian analysis KW - Influenza KW - Fever KW - Guillain-Barre syndrome KW - Disabilities KW - Headache KW - Ataxia KW - Drugs KW - Mortality KW - Data processing KW - Training KW - Safety KW - Children KW - USA KW - Education KW - Reviews KW - Vaccines KW - Side effects KW - F 06905:Vaccines KW - H 4000:Food and Drugs KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1664206158?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Post-licensure+surveillance+of+trivalent+live+attenuated+influenza+vaccine+in+adults%2C+United+States%2C+Vaccine+Adverse+Event+Reporting+System+%28VAERS%29%2C+July+2005-June+2013&rft.au=Haber%2C+Penina%3BMoro%2C+Pedro+L%3BMcNeil%2C+Michael+M%3BLewis%2C+Paige%3BWoo%2C+Emily+Jane%3BHughes%2C+Hayley%3BShimabukuro%2C+Tom+T&rft.aulast=Haber&rft.aufirst=Penina&rft.date=2014-11-01&rft.volume=32&rft.issue=48&rft.spage=6499&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/10.1016%2Fj.vaccine.2014.09.018 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Number of references - 28 N1 - Last updated - 2015-08-05 N1 - SubjectsTermNotLitGenreText - Fever; Influenza; Age; Data processing; Guillain-Barre syndrome; Bayesian analysis; Reviews; Headache; Ataxia; Vaccines; Children; Drugs; Mortality; Education; Training; Disabilities; Safety; Side effects; USA DO - http://dx.doi.org/10.1016/j.vaccine.2014.09.018 ER - TY - JOUR T1 - Integrating antiretroviral therapy in methadone maintenance therapy clinics: service provider perceptions AN - 1652366448; 4644482 AB - Background: Using methadone maintenance therapy (MMT) clinics to deliver antiretroviral therapy (ART) is an effective strategy to promote treatment initiation and adherence for HIV-positive drug users. This paper describes the implementation barriers perceived by service providers for an intervention pilot designed to integrate ART services in MMT clinics. Methods: The study was conducted in six MMT clinics in Sichuan province, China. Two service providers selected from each of the six clinics underwent training in administering ART. The trained providers delivered ART-related services in their clinics. A focus group was conducted among the service providers to assess their experiences and perceived challenges in delivering integrated services. Results: Barriers at policy, institutional, provider, and client levels were identified. Policy level barriers included household registration restrictions and a lack of insurance coverage for testing expenses. Inefficient coordination between treatment sites and MMT clinics was an obstacle at the institutional level. Insufficient training and added workload were barriers at the provider level. Finally, conflict with daily dosing habits was identified as the primary reason that clients did not accept ART. Conclusion: Although integrating ART into MMT clinics is beneficial, multilevel barriers to implementation need to be addressed. This study documents the need for treatment transferability and insurance coverage, protection of client confidentiality, proper provider training, coordination with treatment sites, and individualized ART service for MMT clients. Reprinted by permission of Elsevier Science Inc. JF - International journal of drug policy AU - Li, Li AU - Lin, Chunqing AU - Cao, Xiaobin AD - aUniversity of California, Los Angeles ; Chinese Center for Disease Control and Prevention Y1 - 2014/11// PY - 2014 DA - Nov 2014 SP - 1066 EP - 1070 VL - 25 IS - 6 SN - 0955-3959, 0955-3959 KW - Sociology KW - Medical care KW - Health care KW - Perception KW - Training KW - Patients KW - Medical treatment KW - China KW - Hospitals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1652366448?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+journal+of+drug+policy&rft.atitle=Integrating+antiretroviral+therapy+in+methadone+maintenance+therapy+clinics%3A+service+provider+perceptions&rft.au=Li%2C+Li%3BLin%2C+Chunqing%3BCao%2C+Xiaobin&rft.aulast=Li&rft.aufirst=Li&rft.date=2014-11-01&rft.volume=25&rft.issue=6&rft.spage=1066&rft.isbn=&rft.btitle=&rft.title=International+journal+of+drug+policy&rft.issn=09553959&rft_id=info:doi/10.1016%2Fj.drugpo.2014.04.021 LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2015-02-09 N1 - Last updated - 2015-02-09 N1 - SubjectsTermNotLitGenreText - 12894; 5775 13521; 7875 5775 13521; 7890 5792 10484; 9271 7890 5792 10484; 9382; 6013 6590; 93 116 30 DO - http://dx.doi.org/10.1016/j.drugpo.2014.04.021 ER - TY - GEN T1 - Leveraging birth defects surveillance data for health services research. AN - 1628527949; 25369783 JF - Birth defects research. Part A, Clinical and molecular teratology AU - Cassell, Cynthia H AU - Grosse, Scott D AU - Kirby, Russell S Y1 - 2014/11// PY - 2014 DA - November 2014 SP - 815 EP - 821 VL - 100 IS - 11 KW - Index Medicus KW - Humans KW - Health Surveys KW - Databases, Factual KW - United States -- epidemiology KW - Health Services Research -- statistics & numerical data KW - Health Services Needs and Demand -- statistics & numerical data KW - Health Services Research -- economics KW - Congenital Abnormalities -- epidemiology KW - Epidemiological Monitoring KW - Health Services Research -- trends UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1628527949?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=Birth+defects+research.+Part+A%2C+Clinical+and+molecular+teratology&rft.atitle=Leveraging+birth+defects+surveillance+data+for+health+services+research.&rft.au=Cassell%2C+Cynthia+H%3BGrosse%2C+Scott+D%3BKirby%2C+Russell+S&rft.aulast=Cassell&rft.aufirst=Cynthia&rft.date=2014-11-01&rft.volume=100&rft.issue=11&rft.spage=815&rft.isbn=&rft.btitle=&rft.title=Birth+defects+research.+Part+A%2C+Clinical+and+molecular+teratology&rft.issn=1542-0760&rft_id=info:doi/10.1002%2Fbdra.23330 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2015-07-07 N1 - Date created - 2014-11-26 N1 - Date revised - 2017-01-14 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1002/bdra.23330 ER - TY - JOUR T1 - Effect of living conditions on biochemical and hematological parameters of the cynomolgus monkey AN - 1627699704; 4619757 AB - The cynomolgus monkey (Macaca fascicularis) has been increasingly used in biomedical research. Although living conditions affect behavioral and physiological characteristics in macaques, little data is available on how living conditions influence blood-based parameters in the cynomolgus monkey. We hypothesize that there are significant differences in serum biochemical and hematological parameters in single-caged versus socially housed cynomolgus monkeys, and that age and sex influence the effect of living conditions on these parameters. Sixty single-caged and 60 socially housed cynomolgus monkeys were segregated by age group (juvenile, adult) and sex. The effects of living condition, age, sex, and the interactions between these factors on commonly reported serum biochemical and hematological parameters were analyzed by a three-way analysis of variance (ANOVA). Then, the differences between single-caged and socially housed subjects were tested in each parameter by Student's t-test. Creatinine, glucose, triglyceride, alanine aminotransferase, red blood cell volume distribution width (SD, CV), median fluorescence reticulocyte percentage, white blood cell and basophil counts, and monocyte (count, %) were lower in single-caged subjects. Blood urea nitrogen and globulin were lower in single-caged juveniles and adults, respectively. Red blood cell count, hemoglobin, hematocrit, and neutrophil (count, %) were higher, and reticulocyte and lymphocyte (counts, %) were lower, in single-caged juveniles. Mean corpuscular hemoglobin concentration was higher in single-caged subjects (but more pronounced in adults). Total protein was higher in single-caged juvenile males and lower in single-caged adult females. Alkaline phosphatase was lower in single-caged juvenile females. Mean corpuscular hemoglobin was higher, and high fluorescence reticulocyte percentage was lower, in single-caged adult males. In conclusion, living conditions significantly affect several serum biochemical and hematological parameters in the cynomolgus monkey, and these effects vary by age and sex. As this macaque is commonly housed under different living conditions, these findings should aid researchers in avoiding inaccurate conclusions concerning this species. Am. J. Primatol. 76:1011-1024, 2014. 2014 Wiley Periodicals, Inc. Copyright John Wiley & Sons. Reproduced with permission. An electronic version of this article is available online at http://www.interscience.wiley.com JF - American journal of primatology AU - Gong, Wei AU - Ji, Yongjia AU - Fang, Liang AU - Li, Leilei AU - Melgiri, Narayan D AU - Xie, Peng AU - Xie, Liang AU - Zhou, Qinming AU - Liu, Shigang AU - Xu, Fan AU - Shively, Carol A AU - Wu, Qingyuan AD - Chongqing Medical University ; Wake Forest University ; Chinese Center For Disease Control And Prevention Y1 - 2014/11// PY - 2014 DA - Nov 2014 SP - 1011 EP - 1024 VL - 76 IS - 11 SN - 0275-2565, 0275-2565 KW - Anthropology KW - Blood KW - Primatology KW - Living conditions KW - Primate behaviour KW - Females KW - Old World monkeys UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1627699704?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+journal+of+primatology&rft.atitle=Effect+of+living+conditions+on+biochemical+and+hematological+parameters+of+the+cynomolgus+monkey&rft.au=Gong%2C+Wei%3BJi%2C+Yongjia%3BFang%2C+Liang%3BLi%2C+Leilei%3BMelgiri%2C+Narayan+D%3BXie%2C+Peng%3BXie%2C+Liang%3BZhou%2C+Qinming%3BLiu%2C+Shigang%3BXu%2C+Fan%3BShively%2C+Carol+A%3BWu%2C+Qingyuan&rft.aulast=Gong&rft.aufirst=Wei&rft.date=2014-11-01&rft.volume=76&rft.issue=11&rft.spage=1011&rft.isbn=&rft.btitle=&rft.title=American+journal+of+primatology&rft.issn=02752565&rft_id=info:doi/10.1002%2Fajp.22285 LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2014-11-24 N1 - Last updated - 2014-11-25 N1 - SubjectsTermNotLitGenreText - 10149; 8910 10148; 10144 10148 10149 1542 11325; 1665 1678; 7480 12162 3898; 4865 11538 DO - http://dx.doi.org/10.1002/ajp.22285 ER - TY - JOUR T1 - Antimicrobial resistance in eight US hospitals along the US-Mexico border, 2000-2006 AN - 1622605716; 20811024 AB - Antimicrobial resistance (AR) is a growing problem worldwide and international travel, cross-border migration, and antimicrobial use may contribute to the introduction or emergence of AR. We examined AR rates and trends along the US-Mexico border by analysing microbiology data from eight US hospitals in three states bordering Mexico. Microbiology data were ascertained for the years 2000-2006 and for select healthcare and community pathogens including, three Gram-negative (Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae) and three Gram-positive (Staphylococcus aureus, Enterococcus, Streptococcus pneumoniae) pathogens and 10 antimicrobial-pathogen combinations. Resistance was highest in S. aureus (oxacillin resistance 45.7%), P. aeruginosa (quinolone resistance 22.3%), and E. coli (quinolone resistance 15.6%); six (60%) of the 10 antimicrobial-pathogen combinations studied had a significantly increasing trend in resistance over the study period. Potential contributing factors in the hospital and community such as infection control practices and antimicrobial use (prescription and non-prescription) should be explored further in the US-Mexico border region. JF - Epidemiology and Infection AU - Benoit AU - Ellingson, K D AU - Waterman, Sh AU - Pearson, M L AD - Division of Healthcare Quality Promotion, National Center For Emerging & Zoonotic Infectious Diseases, CDC, Atlanta, GA, USA, bvy8@cdc.gov Y1 - 2014/11// PY - 2014 DA - November 2014 SP - 2378 EP - 2387 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 142 IS - 11 SN - 0950-2688, 0950-2688 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Health & Safety Science Abstracts KW - Travel KW - Drug resistance KW - Quinolones KW - Infection KW - Migration KW - Escherichia coli KW - Pseudomonas aeruginosa KW - Staphylococcus aureus KW - Data processing KW - Oxacillin KW - Pathogens KW - Antimicrobial agents KW - Streptococcus pneumoniae KW - Mexico KW - Health care KW - Enterococcus KW - Klebsiella pneumoniae KW - Hospitals KW - H 12000:Epidemiology and Public Health KW - A 01350:Microbial Resistance UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1622605716?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Antimicrobial+resistance+in+eight+US+hospitals+along+the+US-Mexico+border%2C+2000-2006&rft.au=Benoit%3BEllingson%2C+K+D%3BWaterman%2C+Sh%3BPearson%2C+M+L&rft.aulast=Benoit&rft.aufirst=&rft.date=2014-11-01&rft.volume=142&rft.issue=11&rft.spage=2378&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS095026881300318X LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-11-01 N1 - Number of references - 31 N1 - Last updated - 2016-03-30 N1 - SubjectsTermNotLitGenreText - Travel; Data processing; Drug resistance; Quinolones; Oxacillin; Pathogens; Infection; Migration; Antimicrobial agents; Hospitals; Health care; Streptococcus pneumoniae; Enterococcus; Escherichia coli; Staphylococcus aureus; Pseudomonas aeruginosa; Klebsiella pneumoniae; Mexico DO - http://dx.doi.org/10.1017/S095026881300318X ER - TY - JOUR T1 - Physician Survey to Determine How Dengue Is Diagnosed, Treated and Reported in Puerto Rico AN - 1622611316; 20868873 AB - Dengue is a major cause of morbidity in Puerto Rico and is well-known to its physicians. Early case identification and timely initiation of treatment for patients with severe dengue can reduce medical complications and mortality. To determine clinical management and reporting practices, and assess knowledge of dengue and its management, a survey was sent to 2,512 physicians with a medical license in Puerto Rico. Of the 2,313 physicians who received the survey, 817 (35%) completed the questionnaire. Of the respondents, 708 were currently practicing medicine; 138 were board certified (Group 1), 282 were board eligible (Group 2), and 288 had not finished residency (Group 3). Although respondents clinically diagnosed, on average, 12 cases of dengue in the preceding three months, 31% did not report any suspected cases to public health officials while about half (56%) reported all cases. Overall, 29% of respondents correctly identified early signs of shock and 48% identified severe abdominal pain and persistent vomiting as warning signs for severe dengue with the proportion of correct respondents highest in Group 1. Reportedly about sixty percent (57%) appropriately never give corticosteroids or prophylactic platelet transfusions to dengue patients. One third (30%) of respondents correctly identified administration of intravenous colloid solution as the best treatment option for dengue patients with refractory shock and elevated hematocrit after an initial trial of intravenous crystalloids, and nearly one half (46%) correctly identified administration of a blood transfusion as the best option for dengue patients with refractory shock and decreased hematocrit after a trial of intravenous crystalloids. Even though dengue has been endemic in Puerto Rico for nearly 4 decades, knowledge of dengue management is still limited, compliance with WHO treatment guidelines is suboptimal, and underreporting is significant. These findings were used to design a post graduate training course to improve the clinical management of dengue. Dengue is a major cause of morbidity in Puerto Rico and is well-known to its physicians. Early case identification and timely initiation of treatment for patients with severe dengue can reduce medical complications and mortality. We conducted a survey among physicians who practice in Puerto Rico to determine clinical management and reporting practices and assess knowledge of dengue and its management. We found that although respondents clinically diagnosed, on average, 12 cases of dengue in the preceding three months, one third did not report any suspected cases to public health officials while about half reported all cases. We found that knowledge of dengue management was limited and compliance with WHO treatment guidelines was not optimal. As other dengue endemic countries have reported similar findings, a sustained continuing medical education training initiative may be necessary to improve case detection and clinical management even in countries where the disease is common. Our findings were used to design a postgraduate training course to improve the clinical management of dengue. JF - PLoS Neglected Tropical Diseases AU - Tomashek, Kay M AU - Biggerstaff, Brad J AU - Ramos, Mary M AU - Perez-Guerra, Carmen L AU - Garcia Rivera, Enid J AU - Sun, Wellington AD - Dengue Branch, Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico Y1 - 2014/10/09/ PY - 2014 DA - 2014 Oct 09 PB - Public Library of Science, 185 Berry Street San Francisco CA 94107 United States VL - 8 IS - 10 SN - 1935-2727, 1935-2727 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Human diseases KW - Vomiting KW - Colloids KW - Compliance KW - Disease control KW - Pain KW - Transfusion KW - Clinical trials KW - Morbidity KW - Public health KW - Endemic species KW - Dengue KW - Hematocrit KW - Disease detection KW - Inventories KW - Mortality KW - Intravenous administration KW - Complications KW - Training KW - Guidelines KW - Corticoids KW - Education KW - Blood transfusion KW - Shock KW - ASW, Caribbean Sea, Greater Antilles, Puerto Rico KW - Platelets KW - Mortality causes KW - Q1 08604:Stock assessment and management KW - H 12000:Epidemiology and Public Health KW - Q5 08524:Public health, medicines, dangerous organisms KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1622611316?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=PLoS+Neglected+Tropical+Diseases&rft.atitle=Physician+Survey+to+Determine+How+Dengue+Is+Diagnosed%2C+Treated+and+Reported+in+Puerto+Rico&rft.au=Tomashek%2C+Kay+M%3BBiggerstaff%2C+Brad+J%3BRamos%2C+Mary+M%3BPerez-Guerra%2C+Carmen+L%3BGarcia+Rivera%2C+Enid+J%3BSun%2C+Wellington&rft.aulast=Tomashek&rft.aufirst=Kay&rft.date=2014-10-09&rft.volume=8&rft.issue=10&rft.spage=&rft.isbn=&rft.btitle=&rft.title=PLoS+Neglected+Tropical+Diseases&rft.issn=19352727&rft_id=info:doi/10.1371%2Fjournal.pntd.0003192 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-11-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Education; Endemic species; Human diseases; Colloids; Disease control; Disease detection; Mortality causes; Public health; Mortality; Inventories; Intravenous administration; Vomiting; Pain; Clinical trials; Morbidity; Corticoids; Blood transfusion; Shock; Dengue; Platelets; Hematocrit; Training; Complications; Guidelines; Compliance; Transfusion; ASW, Caribbean Sea, Greater Antilles, Puerto Rico DO - http://dx.doi.org/10.1371/journal.pntd.0003192 ER - TY - JOUR T1 - Fatal Burkholderia pseudomallei Infection Initially Reported as a Bacillus Species, Ohio, 2013 AN - 1753472890; PQ0002164933 AB - A fatal case of melioidosis was diagnosed in Ohio one month after culture results were initially reported as a Bacillus species. To identify a source of infection and assess risk in patient contacts, we abstracted patient charts; interviewed physicians and contacts; genetically characterized the isolate; performed a Burkholderia pseudomallei antibody indirect hemagglutination assay on household contacts and pets to assess seropositivity; and collected household plant, soil, liquid, and insect samples for culturing and real-time polymerase chain reaction testing. Family members and pets tested were seronegative for B. pseudomallei. Environmental samples were negative by real-time polymerase chain reaction and culture. Although the patient never traveled internationally, the isolate genotype was consistent with an isolate that originated in Southeast Asia. This investigation identified the fifth reported locally acquired non-laboratory melioidosis case in the contiguous United States. Physicians and laboratories should be aware of this potentially emerging disease and refer positive cultures to a Laboratory Response Network laboratory. JF - American Journal of Tropical Medicine and Hygiene AU - Doker, Thomas J AU - Quinn, Celia L AU - Salehi, Ellen D AU - Sherwood, Joshua J AU - Benoit, Tina J AU - Elrod, Mindy Glass AU - Gee, Jay E AU - Shadomy, Sean V AU - Bower, William A AU - Hoffmaster, Alex R AU - Walke, Henry T AU - Blaney, David D AU - DiOrio, Mary S AD - Epidemic Intelligence Service, and Bacterial Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, Georgia, thomas.doker@gmail.com Y1 - 2014/10// PY - 2014 DA - October 2014 SP - 743 EP - 746 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 91 IS - 4 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology KW - Burkholderia pseudomallei KW - Soil KW - Pets KW - Antibodies KW - Melioidosis KW - Polymerase chain reaction KW - Genotypes KW - Infection KW - Bacillus KW - Indirect hemagglutination KW - J 02400:Human Diseases KW - K 03310:Genetics & Taxonomy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1753472890?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Fatal+Burkholderia+pseudomallei+Infection+Initially+Reported+as+a+Bacillus+Species%2C+Ohio%2C+2013&rft.au=Doker%2C+Thomas+J%3BQuinn%2C+Celia+L%3BSalehi%2C+Ellen+D%3BSherwood%2C+Joshua+J%3BBenoit%2C+Tina+J%3BElrod%2C+Mindy+Glass%3BGee%2C+Jay+E%3BShadomy%2C+Sean+V%3BBower%2C+William+A%3BHoffmaster%2C+Alex+R%3BWalke%2C+Henry+T%3BBlaney%2C+David+D%3BDiOrio%2C+Mary+S&rft.aulast=Doker&rft.aufirst=Thomas&rft.date=2014-10-01&rft.volume=91&rft.issue=4&rft.spage=743&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0172 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-01-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Soil; Antibodies; Pets; Melioidosis; Polymerase chain reaction; Genotypes; Infection; Indirect hemagglutination; Burkholderia pseudomallei; Bacillus DO - http://dx.doi.org/10.4269/ajtmh.14-0172 ER - TY - JOUR T1 - Formative Investigation of Acceptability of Typhoid Vaccine During a Typhoid Fever Outbreak in Neno District, Malawi AN - 1727695010; PQ0002164931 AB - Typhoid fever affects an estimated 22 million people annually and causes 216,000 deaths worldwide. We conducted an investigation in August and September 2010 to examine the acceptability of typhoid vaccine in Neno District, Malawi where a typhoid outbreak was ongoing. We used qualitative methods, including freelisting exercises, key informant and in-depth interviews, and group discussions. Respondents associated illness with exposure to "bad wind," and transmission was believed to be airborne. Typhoid was considered extremely dangerous because of its rapid spread, the debilitating conditions it produced, the number of related fatalities, and the perception that it was highly contagious. Respondents were skeptical about the effectiveness of water, sanitation, and hygiene (WaSH) interventions. The perceived severity of typhoid and fear of exposure, uncertainty about the effectiveness of WaSH measures, and widespread belief in the efficacy of vaccines in preventing disease resulted in an overwhelming interest in receiving typhoid vaccine during an outbreak. JF - American Journal of Tropical Medicine and Hygiene AU - Blum, Lauren S AU - Dentz, Holly AU - Chingoli, Felix AU - Chilima, Benson AU - Warne, Thomas AU - Lee, Carla AU - Hyde, Terri AU - Gindler, Jacqueline AU - Sejvar, James AU - Mintz, Eric D AD - Waterborne Disease Prevention Branch, Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, (NCEZID), CDC, Atlanta, Georgia, laurensblum@yahoo.com Y1 - 2014/10// PY - 2014 DA - October 2014 SP - 729 EP - 737 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 91 IS - 4 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Fear KW - Disease control KW - Physical training KW - Disease transmission KW - Sanitation KW - Perception KW - Malawi KW - Vaccines KW - Typhoid fever KW - Hygiene KW - Wind KW - K 03400:Human Diseases KW - J 02400:Human Diseases KW - Q1 08485:Species interactions: pests and control KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727695010?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Formative+Investigation+of+Acceptability+of+Typhoid+Vaccine+During+a+Typhoid+Fever+Outbreak+in+Neno+District%2C+Malawi&rft.au=Blum%2C+Lauren+S%3BDentz%2C+Holly%3BChingoli%2C+Felix%3BChilima%2C+Benson%3BWarne%2C+Thomas%3BLee%2C+Carla%3BHyde%2C+Terri%3BGindler%2C+Jacqueline%3BSejvar%2C+James%3BMintz%2C+Eric+D&rft.aulast=Blum&rft.aufirst=Lauren&rft.date=2014-10-01&rft.volume=91&rft.issue=4&rft.spage=729&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0067 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Disease control; Vaccines; Hygiene; Sanitation; Fear; Perception; Typhoid fever; Wind; Disease transmission; Physical training; Malawi DO - http://dx.doi.org/10.4269/ajtmh.14-0067 ER - TY - JOUR T1 - Validation of Self-Reported Smokeless Tobacco Use by Measurement of Serum Cotinine Concentration Among US Adults AN - 1701487035; PQ0001756132 AB - Although investigators have assessed the relationship between self-reported cigarette smoking and biomarker levels, the validity of self-reported information on smokeless tobacco (SLT) use is uncertain. We used aggregated data from the 2003-2004, 2005-2006, 2007-2008, and 2009-2010 administrations of the National Health and Nutrition Examination Survey (NHANES) to compare self-reported SLT use with serum concentrations of cotinine, a metabolite of nicotine, among US adults aged greater than or equal to 18 years. Receiver operating characteristic analysis was used to determine the optimal serum cotinine cutpoint for discriminating SLT users from nonusers of tobacco, and concordance analysis was used to compare self-reported SLT use with cotinine levels. Among the 30,298 adult respondents who completed the NHANES during 2003-2010, 418 reported having exclusively used SLT and no other type of tobacco (cigarettes, cigars, or pipes) during the past 5 days, while 23,457 reported not using any tobacco. The optimal cotinine cutpoint for discriminating SLT users from non-tobacco users was 3.0 ng/mL (sensitivity = 97.0%, specificity = 93.0%), which was comparable to a revised cutpoint recommended for identifying adult cigarette smokers. Concordance with cotinine was 96.4% and 93.7% for self-reported SLT use and tobacco nonuse, respectively. These findings indicate that self-reported SLT use among adults correlates highly with serum cotinine levels and that the optimal cutpoint for minimizing misclassification of self-reported use is a serum cotinine concentration of 3.0 ng/mL. JF - American Journal of Epidemiology AU - Agaku, Israel T AU - King, Brian A AD - Correspondence to Dr. Israel T. Agaku, Office on Smoking and Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway NE, MS F-79, Atlanta, GA 30341., iagaku@cdc.gov Y1 - 2014/10/01/ PY - 2014 DA - 2014 Oct 01 SP - 749 EP - 754 PB - Oxford University Press, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 180 IS - 7 SN - 0002-9262, 0002-9262 KW - Toxicology Abstracts KW - biomarkers KW - cotinine KW - epidemiologic methods KW - smokeless tobacco KW - smoking KW - snuff KW - tobacco KW - Cotinine KW - Data processing KW - Nicotine KW - Cigarette smoking KW - Tobacco KW - Metabolites KW - Nutrition KW - X 24380:Social Poisons & Drug Abuse UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1701487035?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Epidemiology&rft.atitle=Validation+of+Self-Reported+Smokeless+Tobacco+Use+by+Measurement+of+Serum+Cotinine+Concentration+Among+US+Adults&rft.au=Agaku%2C+Israel+T%3BKing%2C+Brian+A&rft.aulast=Agaku&rft.aufirst=Israel&rft.date=2014-10-01&rft.volume=180&rft.issue=7&rft.spage=749&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Epidemiology&rft.issn=00029262&rft_id=info:doi/10.1093%2Faje%2Fkwu182 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-08-01 N1 - Last updated - 2015-11-16 N1 - SubjectsTermNotLitGenreText - Data processing; Cotinine; Nicotine; Cigarette smoking; Tobacco; Metabolites; biomarkers; Nutrition DO - http://dx.doi.org/10.1093/aje/kwu182 ER - TY - JOUR T1 - Does every US smoker bear the same cigarette tax? AN - 1660014466; 2011-731195 AB - To evaluate state cigarette excise tax pass-through rates for selected price-minimizing strategies. Multivariate regression analysis of current smokers from a stratified, national, dual-frame telephone survey. A total of 16 542 adult current smokers aged 18 years or older. Cigarette per pack prices paid with and without coupons were obtained for pack versus carton purchase, use of generic brands versus premium brands, and purchase from Indian reservations versus outside Indian reservations. The average per pack prices paid differed substantially by price-minimizing strategy. Smokers who used any type of price-minimizing strategies paid substantially less than those who did not use these strategies (P < 0.05). Premium brand users who purchased by pack in places outside Indian reservations paid the entire amount of the excise tax, together with an additional premium of 7-10 cents per pack for every $1 increase in excise tax (pass-through rate of 1.07-1.10, P < 0.05). In contrast, carton purchasers, generic brand users or those who were likely to make their purchases on Indian reservations paid only 30-83 cents per pack for every $1 tax increase (pass-through rate of 0.30-0.83, P < 0.05). Many smokers in the United States are able to avoid the full impact of state excise tax on cost of smoking by buying cartons, using generic brands and buying from Indian reservations. Adapted from the source document. JF - Addiction AU - Xu, Xin AU - Malarcher, Ann AU - O'Halloran, Alissa AU - Kruger, Judy AD - Office on Smoking and Health National Center for Chronic Disease Prevention and Health Promotion. Centers for Disease Control and Prevention Y1 - 2014/10// PY - 2014 DA - October 2014 SP - 1741 EP - 1749 PB - Blackwell Publishing, Oxford UK VL - 109 IS - 10 SN - 0965-2140, 0965-2140 KW - Banking and public and private finance - Taxation and tax policy KW - Business and service sector - Business finance KW - Population groups, population policy, and demographics - Demography and census KW - Social conditions and policy - Drinking, smoking, and drug addiction KW - Education and education policy - Statistics, research, research methods, and research support KW - Economic conditions and policy - Economic theory KW - Cost KW - United States KW - Taxation KW - Smoking KW - Indians Reservations KW - Prices KW - Telephone surveys KW - Adults KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1660014466?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Addiction&rft.atitle=Does+every+US+smoker+bear+the+same+cigarette+tax%3F&rft.au=Xu%2C+Xin%3BMalarcher%2C+Ann%3BO%27Halloran%2C+Alissa%3BKruger%2C+Judy&rft.aulast=Xu&rft.aufirst=Xin&rft.date=2014-10-01&rft.volume=109&rft.issue=10&rft.spage=1741&rft.isbn=&rft.btitle=&rft.title=Addiction&rft.issn=09652140&rft_id=info:doi/10.1111%2Fadd.12630 LA - English DB - PAIS Index N1 - Date revised - 2015-03-01 N1 - Last updated - 2016-09-28 N1 - CODEN - ADICE5 N1 - SubjectsTermNotLitGenreText - Indians Reservations; Taxation; United States; Prices; Adults; Smoking; Telephone surveys; Cost DO - http://dx.doi.org/10.1111/add.12630 ER - TY - JOUR T1 - Molecular Epidemiology of the Pertussis Epidemic in Washington State in 2012 AN - 1622600620; 20856328 AB - Although pertussis disease is vaccine preventable, Washington State experienced a substantial rise in pertussis incidence beginning in 2011. By June 2012, the reported cases reached 2,520 (37.5 cases per 100,000 residents), a 1,300% increase compared with the same period in 2011. We assessed the molecular epidemiology of this statewide epidemic using 240 isolates collected from case patients reported from 19 of 39 Washington counties during 2012 to 2013. The typing methods included pulsed-field gel electrophoresis (PFGE), multilocus variable number tandem repeat analysis (MLVA), multilocus sequence typing (MLST), and pertactin gene (prn) mutational analysis. Using the scheme PFGE-MLVA-MLST-prn mutations-Prn deficiency, the 240 isolates comprised 65 distinct typing profiles. Thirty-one PFGE types were found, with the most common types, CDC013 (n = 51), CDC237 (n = 44), and CDC002 (n = 42), accounting for 57% of them. Eleven MLVA types were observed, mainly comprising type 27 (n = 183, 76%). Seven MLST types were identified, with the majority of the isolates typing as prn2-ptxP3-ptxA1-fim3-1 (n = 157, 65%). Four different prn mutations accounted for the 76% of isolates exhibiting pertactin deficiency. PFGE provided the highest discriminatory power (D = 0.87) and was found to be a more powerful typing method than MLVA and MLST combined (D = 0.67). This study provides evidence for the continued predominance of MLVA 27 and prn2-ptxP3-ptxA1 alleles, along with the reemergence of the fim3-1 allele. Our results indicate that the Bordetella pertussis population causing this epidemic was diverse, with a few molecular types predominating. The PFGE, MLVA, and MLST profiles were consistent with the predominate types circulating in the United States and other countries. For prn, several mutations were present in multiple molecular types. JF - Journal of Clinical Microbiology AU - Bowden, Katherine E AU - Williams, Margaret M AU - Cassiday, Pamela K AU - Milton, Andrea AU - Pawloski, Lucia AU - Harrison, Marsenia AU - Martin, Stacey W AU - Meyer, Sarah AU - Qin, Xuan AU - DeBolt, Chas AD - Centers for Disease Control and Prevention, Atlanta, Georgia, USA, mlt5@cdc.gov. Y1 - 2014/10// PY - 2014 DA - October 2014 SP - 3549 EP - 3557 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 52 IS - 10 SN - 0095-1137, 0095-1137 KW - Health & Safety Science Abstracts KW - USA, Washington KW - Bordetella pertussis KW - Electrophoresis KW - Epidemiology KW - Vaccines KW - Mutation KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1622600620?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Molecular+Epidemiology+of+the+Pertussis+Epidemic+in+Washington+State+in+2012&rft.au=Bowden%2C+Katherine+E%3BWilliams%2C+Margaret+M%3BCassiday%2C+Pamela+K%3BMilton%2C+Andrea%3BPawloski%2C+Lucia%3BHarrison%2C+Marsenia%3BMartin%2C+Stacey+W%3BMeyer%2C+Sarah%3BQin%2C+Xuan%3BDeBolt%2C+Chas&rft.aulast=Bowden&rft.aufirst=Katherine&rft.date=2014-10-01&rft.volume=52&rft.issue=10&rft.spage=3549&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.01189-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-11-01 N1 - Number of references - 42 N1 - Last updated - 2016-07-20 N1 - SubjectsTermNotLitGenreText - Electrophoresis; Epidemiology; Vaccines; Mutation; Bordetella pertussis; USA, Washington DO - http://dx.doi.org/10.1128/JCM.01189-14 ER - TY - RPRT T1 - CENTERS FOR DISEASE CONTROL AND PREVENTION ROYBAL CAMPUS 2025 MASTER PLAN, DEKALB COUNTY, GEORGIA. AN - 1672869421; 16245 AB - PURPOSE: A master plan to guide the future physical development of the CDCs Edward R. Roybal Campus for the planning horizon of 2015 to 2015 is proposed. The Roybal Campus is situated on 46.7 acres, just outside the city limits of the City of Atlanta in DeKalb County, Georgia. The campus is located between Interstate 85 and 20 and is located within the Clifton Corridor, which is a transportation corridor that extends along Clifton Road and includes a mix of neighborhoods, activity centers and thoroughfares within unincorporated DeKalb County, the City of Atlanta, and the City of Decatur. The Clifton Corridor represents one of the largest employment centers within the metro Atlanta area and is home to several major employers including the CDC, Emory University, Emory Healthcare, and the Veterans Affairs Medical Center. The Hartsfield-Jackson International Airport is located approximately 16 miles southwest of the campus. The Roybal Campus is located adjacent to Emory University and is surrounded by a mix of residential and institutional uses. Decatur Station, the closest MARTA station, is located approximately 2 miles southwest of the campus. The following eight Master Plan conceptual alternatives were evaluated for this final EIS: (1) No Action, (2) Increase Space Efficiency, (3a) Lab-Office Mix Moderate, (3b) Lab-Office Full-Build, (4) Office Focus, (5a) Lab Focus Moderate, (5b) Lab Focus Full-Build, and (6) Relocation. Of the eight alternatives, two alternatives were deemed viable to be carried forward in the final EIS for detailed analysis, the No Action and Lab Focus Moderate alternatives. The Lab Focus Moderate alternative, also the CDCs Preferred Alternative, includes new laboratory construction, building renovation, parking expansion, and additional improvements to campus infrastructure. The new laboratory building would measure approximately 350,000 to 450,000 gsf which would include approximately 60,000 gsf of below grade space. The new 1,600 space parking deck would be constructed in the southeastern portion of the campus, which currently consists of a surface parking lot and an existing transshipping facility. As part of the new parking deck construction, a new chilled water storage unit would be constructed in order to meet water usage reduction, energy reduction, and efficiency objectives. The No Action Alternative represented continued operation of the existing facilities at the Roybal Campus without any new construction of any major renovations of interiors or building additions over the ten-year planning period from 2015 to 2025. POSITIVE IMPACTS: Physical development of the Roybal Campus would: (1) accommodate current and future multi-program needs; (2) promote a collaborative research environment; (3) balance future development needs with site constraints and opportunities; and (4) promote overall visual and aesthetic continuity of the 2000-2009 Master Plan through the application of design guidelines for buildings. Implementation of the Preferred Alternative would increase the employee population by approximately 1,485 new occupants, from the current total of 5,308 to 6,793 in 2025. NEGATIVE IMPACTS: The Preferred Alternative would contribute to increased traffic within the Study Area which may affect fire and emergency response times. The Preferred Alternative would result in an increase in electricity, domestic water, natural gas consumption and sewage generation on campus, as well as increase the demand for steam and chilled water. JF - EPA number: 140250, Final EIS Volume I--286 pages, Volume II--612 pages, September 5, 2014 PY - 2014 KW - Urban and Social Programs KW - Air Quality KW - Biologic Assessments KW - Demolition KW - Land Use KW - Buildings KW - Cultural Resources KW - Floodplains KW - Traffic Analyses KW - Noise KW - Parking KW - Public Health KW - Research Facilities KW - Safety KW - Visual Resources KW - Water Resources KW - Wetlands KW - Georgia UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1672869421?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/Environmental+Impact+Statements%3A+Digests&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=report&rft.jtitle=&rft.atitle=&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2014-09-05&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=CENTERS+FOR+DISEASE+CONTROL+AND+PREVENTION+ROYBAL+CAMPUS+2025+MASTER+PLAN%2C+DEKALB+COUNTY%2C+GEORGIA.&rft.title=CENTERS+FOR+DISEASE+CONTROL+AND+PREVENTION+ROYBAL+CAMPUS+2025+MASTER+PLAN%2C+DEKALB+COUNTY%2C+GEORGIA.&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Name - Department of Health and Human Services, Center for Disease Control and Prevention, Atlanta, Georgia; HHS N1 - Date revised - 2015-04-01 N1 - SuppNotes - Final. Preparation date: September 5, 2014 N1 - Last updated - 2015-04-14 ER - TY - JOUR T1 - Relationship Between Frequency and Intensity of Cigarette Smoking and TTFC/C Among Students of the GYTS in Select Countries, 2007‐2009 AN - 1748687953 AB - This study assessed the construct validity of a measure of nicotine dependence that was used in the Global Youth Tobacco Survey (GYTS). Using 2007‐2009 data from the GYTS, subjects from 6 countries were used to assess current smokers' odds of reporting time to first cigarette or craving positive (TTFC/C+) by the number of cigarette smoking days per month (DPM) and the number of cigarettes smoked per day (CPD). The percentage of GYTS smokers who reported TTFC/C+ ranged from 58.0% to 69.7%. Compared with students who smoked on 1‐2 DPM, those who smoked on 3‐9 DPM had 3 times the adjusted odds of reporting TTFC/C+. The adjusted odds of reporting TTFC/C+ were 3 to 7 times higher among those who smoked 10‐29 DPM and 6 to 20 times higher among daily smokers. Similarly, the adjusted odds of TTFC/C+ were 3‐6 times higher among those who smoked 2‐5 CPD and 6 to 20 times higher among those who smoked > 6 CPD, compared to those who smoked < 1 CPD. Associations of TTFC/C+ prevalence with both frequency and intensity of cigarette smoking provide a construct validation of the GYTS question used to assess respondents' TTFC/C status. JF - The Journal of School Health AU - Lam, Eugene AU - Giovino, Gary A AU - Shin, Mikyong AU - Lee, Kyung A AU - Rolle, Italia AU - Asma, Samira AD - Epidemic Intelligence Service, Office of Surveillance. Epidemiology, and Laboratory Services, Centers for Disease Control and Prevention elam@cdc.gov; Department of Community Health and Health Behavior, School of Public Health and Health Professions. University at Buffalo, State University of New York ggiovino@buffalo.edu; Global Tobacco Control Branch, Office on Smoking and Health. National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention fqx6@cdc.gov itr2@cdc.gov sea5@cdc.gov; Northrup Grumman Information Systems inx6@cdc.gov; Epidemic Intelligence Service, Office of Surveillance. Epidemiology, and Laboratory Services, Centers for Disease Control and Prevention Y1 - 2014/09// PY - 2014 DA - Sep 2014 SP - 549 EP - 558 CY - Kent PB - Wiley Subscription Services, Inc. VL - 84 IS - 9 SN - 0022-4391 KW - Physical Fitness And Hygiene KW - Cigarettes KW - Construct validity KW - Craving KW - Drug dependency KW - Nicotine KW - Prevalence KW - Smokers KW - Smoking KW - Tobacco KW - Validation KW - Young people UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1748687953?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+School+Health&rft.atitle=Relationship+Between+Frequency+and+Intensity+of+Cigarette+Smoking+and+TTFC%2FC+Among+Students+of+the+GYTS+in+Select+Countries%2C+2007%E2%80%902009&rft.au=Lam%2C+Eugene%3BGiovino%2C+Gary+A%3BShin%2C+Mikyong%3BLee%2C+Kyung+A%3BRolle%2C+Italia%3BAsma%2C+Samira&rft.aulast=Lam&rft.aufirst=Eugene&rft.date=2014-09-01&rft.volume=84&rft.issue=9&rft.spage=549&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+School+Health&rft.issn=00224391&rft_id=info:doi/10.1111%2Fjosh.12185 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2014-10-14 N1 - Last updated - 2016-05-24 DO - http://dx.doi.org/10.1111/josh.12185 ER - TY - JOUR T1 - Phylogeography of Rickettsia rickettsii Genotypes Associated with Fatal Rocky Mountain Spotted Fever AN - 1722179600; PQ0002099231 AB - Rocky Mountain spotted fever (RMSF), a tick-borne zoonosis caused by Rickettsia rickettsii, is among the deadliest of all infectious diseases. To identify the distribution of various genotypes of R. rickettsii associated with fatal RMSF, we applied molecular typing methods to samples of DNA extracted from formalin-fixed, paraffin-embedded tissue specimens obtained at autopsy from 103 case-patients from seven countries who died of RMSF. Complete sequences of one or more intergenic regions were amplified from tissues of 30 (29%) case-patients and revealed a distribution of genotypes consisting of four distinct clades, including the Flip clade, regarded previously as a non-pathogenic strain of R. rickettsii. Distinct phylogeographic patterns were identified when composite case-patient and reference strain data were mapped to the state and country of origin. The phylogeography of R. rickettsii is likely determined by ecological and environmental factors that exist independently of the distribution of a particular tick vector. JF - American Journal of Tropical Medicine and Hygiene AU - Paddock, Christopher D AU - Denison, Amy M AU - Lash, R Ryan AU - Liu, Lindy AU - Bollweg, Brigid C AU - Dahlgren, F Scott AU - Kanamura, Cristina T AU - Angerami, Rodrigo N AU - Pereira, Fabiana C AU - Martines, Roosecelis Brasil AU - Karpathy, Sandor E AD - Infectious Diseases Pathology Branch and Rickettsial Zoonoses Branch, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, cdp9@cdc.gov Y1 - 2014/09// PY - 2014 DA - September 2014 SP - 589 EP - 597 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 91 IS - 3 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Autopsy KW - Data processing KW - Ixodidae KW - Nucleotide sequence KW - Ecological distribution KW - Vectors KW - Genotypes KW - Hosts KW - Environmental factors KW - North America, Rocky Mts. KW - Rocky Mountain spotted fever KW - Infectious diseases KW - DNA KW - Rickettsia rickettsii KW - Hygiene KW - Q1 08422:Environmental effects KW - Q5 08524:Public health, medicines, dangerous organisms KW - K 03310:Genetics & Taxonomy KW - J 02450:Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1722179600?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Phylogeography+of+Rickettsia+rickettsii+Genotypes+Associated+with+Fatal+Rocky+Mountain+Spotted+Fever&rft.au=Paddock%2C+Christopher+D%3BDenison%2C+Amy+M%3BLash%2C+R+Ryan%3BLiu%2C+Lindy%3BBollweg%2C+Brigid+C%3BDahlgren%2C+F+Scott%3BKanamura%2C+Cristina+T%3BAngerami%2C+Rodrigo+N%3BPereira%2C+Fabiana+C%3BMartines%2C+Roosecelis+Brasil%3BKarpathy%2C+Sandor+E&rft.aulast=Paddock&rft.aufirst=Christopher&rft.date=2014-09-01&rft.volume=91&rft.issue=3&rft.spage=589&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0146 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-10-26 N1 - SubjectsTermNotLitGenreText - Infectious diseases; Ecological distribution; Nucleotide sequence; DNA; Hosts; Genotypes; Hygiene; Environmental factors; Autopsy; Rocky Mountain spotted fever; Data processing; Vectors; Ixodidae; Rickettsia rickettsii; North America, Rocky Mts. DO - http://dx.doi.org/10.4269/ajtmh.14-0146 ER - TY - JOUR T1 - Correlates of syphilis seropositivity and risk for syphilis-associated adverse pregnancy outcomes among women attending antenatal care clinics in the Democratic Republic of Congo AN - 1717493181; PQ0002006193 AB - Screening and treatment for syphilis among pregnant women is the primary means of prevention of congenital syphilis. Sentinel surveillance for syphilis can inform these prevention efforts. We reviewed antenatal syphilis screening results to assess trends and to identify correlates of seropositivity among women attending antenatal care clinics in the Democratic Republic of Congo during 2011. Syphilis seropositivity among the 17,669 women attending the antenatal care clinics during 2011 was 4.2% (range 0.4%-16.9%). Syphilis seropositivity was significantly higher among women attending rural clinics (5.0%) as compared to urban clinics (3.0%) and those tested in antenatal care clinics in the provinces of Equateur (7.6%) and Orientale (7.7%) as compared to other provinces (p < 0.001). Based on the antenatal care syphilis seroprevalence and national pregnancy estimates, we estimate that approximately 128,591 pregnant women countrywide would have tested seropositive for syphilis during 2011. Over 85,000 adverse pregnancy outcomes would have resulted from these maternal infections, assuming prenatal syphilis diagnosis and treatment were not available. The prevalence of syphilis was highest in rural areas, but exceeded 1% in every area, indicating a need to assure screening and treatment throughout Democratic Republic of Congo. These sentinel surveillance estimates can be used to guide national congenital syphilis prevention efforts. JF - International Journal of STD & AIDS AU - Taylor, Melanie M AU - Ebrahim, Shahul AU - Abiola, Nadine AU - Kinkodi, Didine Kaba AU - Mpingulu, Minlangu AU - Kabuayi, Jean Pierre AU - Ekofo, Felly AU - Newman, Daniel R AU - Peterman, Thomas A AU - Kamb, Mary L AU - Sidibe, Kassim AD - Centers for Disease Control and Prevention, Division of STD Prevention, Atlanta, GA, USA, MDT7@CDC.GOV PY - 2014 SP - 716 EP - 725 PB - Sage Publications, Inc., 2455 Teller Road Thousand Oaks CA 91320 United States VL - 25 IS - 10 SN - 0956-4624, 0956-4624 KW - Health & Safety Science Abstracts; Microbiology Abstracts B: Bacteriology; Risk Abstracts; Virology & AIDS Abstracts KW - Syphilis KW - congenital syphilis KW - antenatal care KW - Democratic Republic of Congo KW - STD KW - STI KW - screening KW - prevention KW - seroprevalence KW - Risk assessment KW - Acquired immune deficiency syndrome KW - Prenatal experience KW - Infection KW - Pregnancy KW - Prevention KW - Reviews KW - Treponema pallidum KW - Females KW - Sexually transmitted diseases KW - Rural areas KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health KW - J 02400:Human Diseases KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1717493181?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+STD+%26+AIDS&rft.atitle=Correlates+of+syphilis+seropositivity+and+risk+for+syphilis-associated+adverse+pregnancy+outcomes+among+women+attending+antenatal+care+clinics+in+the+Democratic+Republic+of+Congo&rft.au=Taylor%2C+Melanie+M%3BEbrahim%2C+Shahul%3BAbiola%2C+Nadine%3BKinkodi%2C+Didine+Kaba%3BMpingulu%2C+Minlangu%3BKabuayi%2C+Jean+Pierre%3BEkofo%2C+Felly%3BNewman%2C+Daniel+R%3BPeterman%2C+Thomas+A%3BKamb%2C+Mary+L%3BSidibe%2C+Kassim&rft.aulast=Taylor&rft.aufirst=Melanie&rft.date=2014-09-01&rft.volume=25&rft.issue=10&rft.spage=716&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+STD+%26+AIDS&rft.issn=09564624&rft_id=info:doi/10.1177%2F0956462413518194 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-09-01 N1 - Last updated - 2015-12-23 N1 - SubjectsTermNotLitGenreText - Reviews; Infection; Syphilis; Pregnancy; Risk assessment; Acquired immune deficiency syndrome; Prevention; Prenatal experience; Females; Sexually transmitted diseases; Rural areas; Treponema pallidum DO - http://dx.doi.org/10.1177/0956462413518194 ER - TY - JOUR T1 - Fall Prevention Research and Practice: A Total Worker Safety Approach AN - 1627956581; 20906967 AB - Slips, trips, and falls (STF) represent a serious hazard to workers and occupants in many industries, homes, and communities. Often, the cause of a STF incident is multifactorial, encompassing human, environmental, and task risk factors. A STF-related disability can greatly diminish the occupational capability and quality of life of individuals in both the workplace and the home. Countering STF hazards and risks both on and off the job and on all aspects of control measures is a "total worker safety" matter, a challenging yet tangible undertaking. As the federal organization responsible for conducting research for the prevention of work-related injuries in the United States, the National Institute for Occupational Safety and Health (NIOSH) has been conducting research on STF controls for some decades. Many NIOSH research outcomes have been utilized for STF prevention in workplaces, with potential for prevention in homes as well. This paper summarizes the concept of total worker safety for STF control, NIOSH priority research goals, major activities, and accomplishments, and some emerging issues on STF. The strategic planning process for the NIOSH research goals and some identified research focuses are applicable to the development and implementation of global STF research goals. JF - Industrial Health AU - HSIAO, Hongwei AD - National Institute for Occupational Safety and Health, USA, hxh4@cdc.gov Y1 - 2014/09// PY - 2014 DA - Sep 2014 SP - 381 EP - 392 PB - National Institute of Industrial Health. Japan., 21-1 Nagao 6-chome Kawasaki-shi 214-0023 Kanagawa-ken Japan VL - 52 IS - 5 SN - 0019-8366, 0019-8366 KW - Health & Safety Science Abstracts; Risk Abstracts KW - Falls KW - Construction KW - Healthcare KW - Trade KW - Human characteristics KW - Public safety KW - Control measure KW - USA KW - Prevention KW - Injuries KW - Risk factors KW - Disabilities KW - Occupational safety KW - Safety KW - Priorities KW - Quality of life KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1627956581?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Industrial+Health&rft.atitle=Fall+Prevention+Research+and+Practice%3A+A+Total+Worker+Safety+Approach&rft.au=HSIAO%2C+Hongwei&rft.aulast=HSIAO&rft.aufirst=Hongwei&rft.date=2014-09-01&rft.volume=52&rft.issue=5&rft.spage=381&rft.isbn=&rft.btitle=&rft.title=Industrial+Health&rft.issn=00198366&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-11-01 N1 - Last updated - 2015-04-16 N1 - SubjectsTermNotLitGenreText - Prevention; Injuries; Disabilities; Risk factors; Safety; Occupational safety; Priorities; Quality of life; USA ER - TY - JOUR T1 - Increase in anti-tuberculosis drug resistance in Botswana: results from the fourth National Drug Resistance Survey AN - 1566859538; 20756810 AB - SETTING: Although approximately 0.5 million cases of multidrug-resistant tuberculosis (MDR-TB) occur globally each year, surveillance data are limited. Botswana is one of the few high TB burden countries to have carried out multiple anti-tuberculosis drug resistance surveys (in 1995-1996,1999 and 2002). OBJECTIVE: In 2007-2008, we conducted the fourth national survey of anti-tuberculosis drug resistance in Botswana to assess anti-tuberculosis drug resistance, including trends over time. In the previous survey, 0.8% (95%CI 0.4-1.5) of new patients and 10.4% (95%CI 5.6-17.3) of previously treated patients had MDR-TB. DESIGN: During the survey period, eligible specimens from all new sputum-smear positive TB patients and from all TB patients with history of previous anti-tuberculosis treatment underwent mycobacterial culture and anti-tuberculosis drug susceptibility testing (DST). RESULTS: Of 924 new TB patients and 137 with previous anti-tuberculosis treatment with DST results, respectively 23 (2.5%, 95%CI 1.6-3.7) and 9 (6.6%, 95%CI 3.3-11.7) had MDR-TB. The proportion of new TB patients with MDR-TB has tripled in Botswana since the previous survey. CONCLUSION: Combatting drug-resistant TB will require the scale-up of MDR-TB diagnosis and treatment to prevent the transmission of MDR-TB and strengthening of general TB control to prevent the emergence of resistance. JF - International Journal of Tuberculosis and Lung Disease AU - Menzies, H J AU - Moalosi, G AU - Anisimova, V AU - Gammino, V AU - Sentie, C AU - Bachhuber, M A AU - Bile, E AU - Radisowa, K AU - Kachuwaire, O AU - Basotli, J AD - US Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, USA, hmenzies@cdc.gov Y1 - 2014/09// PY - 2014 DA - Sep 2014 SP - 1026 EP - 1033 PB - International Union Against Tuberculosis and Lung Disease, 68 bvd Saint-Michel Paris 75006 France VL - 18 IS - 9 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology KW - tuberculosis KW - drug resistance KW - surveillance KW - Data processing KW - Mycobacterium KW - Drug resistance KW - Lung diseases KW - Tuberculosis KW - Drug development KW - Drugs KW - Disease transmission KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1566859538?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Increase+in+anti-tuberculosis+drug+resistance+in+Botswana%3A+results+from+the+fourth+National+Drug+Resistance+Survey&rft.au=Menzies%2C+H+J%3BMoalosi%2C+G%3BAnisimova%2C+V%3BGammino%2C+V%3BSentie%2C+C%3BBachhuber%2C+M+A%3BBile%2C+E%3BRadisowa%2C+K%3BKachuwaire%2C+O%3BBasotli%2C+J&rft.aulast=Menzies&rft.aufirst=H&rft.date=2014-09-01&rft.volume=18&rft.issue=9&rft.spage=1026&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/10.5588%2Fijtld.13.0749 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Last updated - 2015-04-16 N1 - SubjectsTermNotLitGenreText - Data processing; Drug resistance; Lung diseases; Drug development; Tuberculosis; Drugs; Disease transmission; Mycobacterium DO - http://dx.doi.org/10.5588/ijtld.13.0749 ER - TY - JOUR T1 - In Vitro Efficacy of Brincidofovir against Variola Virus AN - 1566849374; 20698191 AB - Brincidofovir (CMX001), a lipid conjugate of the acyclic nucleotide phosphonate cidofovir, is under development for smallpox treatment using "the Animal Rule," established by the FDA in 2002. Brincidofovir reduces mortality caused by orthopoxvirus infection in animal models. Compared to cidofovir, brincidofovir has increased potency, is administered orally, and shows no evidence of nephrotoxicity. Here we report that the brincidofovir half-maximal effective concentration (EC50) against five variola virus strains in vitro averaged 0.11 mu M and that brincidofovir was therefore nearly 100-fold more potent than cidofovir. JF - Antimicrobial Agents & Chemotherapy AU - Olson, Victoria A AU - Smith, Scott K AU - Foster, Scott AU - Li, Yu AU - Lanier, E Randall AU - Gates, Irina AU - Trost, Lawrence C AU - Damon, Inger K AD - Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases, Division of High-Consequence Pathogens and Pathology, Poxvirus and Rabies Branch, Atlanta, Georgia, USA, iad7@cdc.gov. Y1 - 2014/09// PY - 2014 DA - Sep 2014 SP - 5570 EP - 5571 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 58 IS - 9 SN - 0066-4804, 0066-4804 KW - Virology & AIDS Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Cidofovir KW - Smallpox KW - Orthopoxvirus KW - Mortality KW - phosphonates KW - Lipids KW - Animal models KW - Infection KW - Nucleotides KW - Variola virus KW - A 01340:Antibiotics & Antimicrobials KW - V 22410:Animal Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1566849374?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=In+Vitro+Efficacy+of+Brincidofovir+against+Variola+Virus&rft.au=Olson%2C+Victoria+A%3BSmith%2C+Scott+K%3BFoster%2C+Scott%3BLi%2C+Yu%3BLanier%2C+E+Randall%3BGates%2C+Irina%3BTrost%2C+Lawrence+C%3BDamon%2C+Inger+K&rft.aulast=Olson&rft.aufirst=Victoria&rft.date=2014-09-01&rft.volume=58&rft.issue=9&rft.spage=5570&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.02814-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Number of references - 13 N1 - Last updated - 2014-12-11 N1 - SubjectsTermNotLitGenreText - Smallpox; Cidofovir; Mortality; phosphonates; Lipids; Animal models; Infection; Nucleotides; Orthopoxvirus; Variola virus DO - http://dx.doi.org/10.1128/AAC.02814-14 ER - TY - JOUR T1 - Comprehensive Comparison of Cultivable Norovirus Surrogates in Response to Different Inactivation and Disinfection Treatments AN - 1566848933; 20698331 AB - Human norovirus is the leading cause of epidemic and sporadic acute gastroenteritis. Since no cell culture method for human norovirus exists, cultivable surrogate viruses (CSV), including feline calicivirus (FCV), murine norovirus (MNV), porcine enteric calicivirus (PEC), and Tulane virus (TuV), have been used to study responses to inactivation and disinfection methods. We compared the levels of reduction in infectivities of CSV and Aichi virus (AiV) after exposure to extreme pHs, 56 degree C heating, alcohols, chlorine on surfaces, and high hydrostatic pressure (HHP), using the same matrix and identical test parameters for all viruses, as well as the reduction of human norovirus RNA levels under these conditions. At pH 2, FCV was inactivated by 6 log10 units, whereas MNV, TuV, and AiV were resistant. All CSV were completely inactivated at 56 degree C within 20 min. MNV was inactivated 5 log10 units by alcohols, in contrast to 2 and 3 log10 units for FCV and PEC, respectively. TuV and AiV were relatively insensitive to alcohols. FCV was reduced 5 log10 units by 1,000 ppm chlorine, in contrast to 1 log10 unit for the other CSV. All CSV except FCV, when dried on stainless steel surfaces, were insensitive to 200 ppm chlorine. HHP completely inactivated FCV, MNV, and PEC at greater than or equal to 300 MPa, and TuV at 600 MPa, while AiV was completely resistant to HHP up to 800 MPa. By reverse transcription-quantitative PCR (RT-qPCR), genogroup I (GI) noroviruses were more sensitive than GII noroviruses to alcohols, chlorine, and HHP. Although inactivation profiles were variable for each treatment, TuV and MNV were the most resistant CSV overall and therefore are the best candidates for studying the public health outcomes of norovirus infections. JF - Applied and Environmental Microbiology AU - Cromeans, Theresa AU - Park, Geun Woo AU - Costantini, Veronica AU - Lee, David AU - Wang, Qiuhong AU - Farkas, Tibor AU - Lee, Alvin AU - Vinje, Jan AD - Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, jvinje@cdc.gov. PY - 2014 SP - 5743 EP - 5751 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 80 IS - 18 SN - 0099-2240, 0099-2240 KW - Virology & AIDS Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Disinfection KW - Aichi virus KW - Porcine enteric calicivirus KW - Epidemics KW - Chlorine KW - Norovirus KW - Cell culture KW - Infection KW - Public health KW - Infectivity KW - RNA KW - Feline calicivirus KW - alcohols KW - Polymerase chain reaction KW - Gastroenteritis KW - Pressure KW - pH effects KW - stainless steel KW - A 01340:Antibiotics & Antimicrobials KW - V 22410:Animal Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1566848933?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Comprehensive+Comparison+of+Cultivable+Norovirus+Surrogates+in+Response+to+Different+Inactivation+and+Disinfection+Treatments&rft.au=Cromeans%2C+Theresa%3BPark%2C+Geun+Woo%3BCostantini%2C+Veronica%3BLee%2C+David%3BWang%2C+Qiuhong%3BFarkas%2C+Tibor%3BLee%2C+Alvin%3BVinje%2C+Jan&rft.aulast=Cromeans&rft.aufirst=Theresa&rft.date=2014-09-01&rft.volume=80&rft.issue=18&rft.spage=5743&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/10.1128%2FAEM.01532-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Number of references - 72 N1 - Last updated - 2016-01-21 N1 - SubjectsTermNotLitGenreText - Disinfection; Epidemics; Chlorine; Cell culture; Infection; Public health; Infectivity; RNA; alcohols; Polymerase chain reaction; Pressure; Gastroenteritis; pH effects; stainless steel; Aichi virus; Porcine enteric calicivirus; Feline calicivirus; Norovirus DO - http://dx.doi.org/10.1128/AEM.01532-14 ER - TY - JOUR T1 - Influenza Virus Infectivity and Virulence following Ocular-Only Aerosol Inoculation of Ferrets AN - 1566847462; 20698537 AB - Respiratory pathogens have traditionally been studied by examining the exposure and infection of respiratory tract tissues. However, these studies typically overlook the role of ocular surfaces, which represent both a potential site of virus replication and a portal of entry for the establishment of a respiratory infection. To model transocular virus entry in a mammalian species, we established a novel inoculation method that delivers an aerosol inoculum exclusively to the ferret ocular surface. Using influenza virus as a representative respiratory pathogen, we found that both human and avian viruses mounted productive respiratory infections in ferrets following ocular-only aerosol inoculation, and we demonstrated that H5N1 virus can result in a fatal infection at doses below 10 PFU or with exposure times as short as 2 min. Ferrets inoculated by the ocular aerosol route with an avian (H7N7, H7N9) or human (H1N1, H3N2v) virus were capable of transmitting the virus to naive animals in direct-contact or respiratory-droplet models, respectively. Our results reveal that ocular-only exposure to virus-containing aerosols constitutes a valid exposure route for a potentially fatal respiratory infection, even for viruses that do not demonstrate an ocular tropism, underscoring the public health implications of ocular exposure in clinical or occupational settings. IMPORTANCE In the absence of eye protection, the human ocular surface remains vulnerable to infection with aerosolized respiratory viruses. In this study, we present a way to inoculate laboratory mammals that excludes respiratory exposure, infecting ferrets only by ocular exposure to influenza virus-containing aerosols. This study demonstrates that the use of respiratory protection alone does not fully protect against influenza virus exposure, infection, and severe disease. JF - Journal of Virology AU - Belser, Jessica A AU - Gustin, Kortney M AU - Katz, Jacqueline M AU - Maines, Taronna R AU - Tumpey, Terrence M Y1 - 2014/09// PY - 2014 DA - Sep 2014 SP - 9647 EP - 9654 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 88 IS - 17 SN - 0022-538X, 0022-538X KW - Ermines KW - Ferrets KW - Minks KW - Weasels KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Mammals KW - Eye KW - Viruses KW - Infection KW - Models KW - Public health KW - Virulence KW - Influenza KW - Mustela KW - Inoculum KW - Vulnerability KW - Occupational exposure KW - Respiratory tract KW - Aerosols KW - Replication KW - Tropism KW - Pathogens KW - Respiratory tract diseases KW - Infectivity KW - Influenza virus KW - Inoculation KW - V 22320:Replication KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1566847462?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Virology&rft.atitle=Influenza+Virus+Infectivity+and+Virulence+following+Ocular-Only+Aerosol+Inoculation+of+Ferrets&rft.au=Belser%2C+Jessica+A%3BGustin%2C+Kortney+M%3BKatz%2C+Jacqueline+M%3BMaines%2C+Taronna+R%3BTumpey%2C+Terrence+M&rft.aulast=Belser&rft.aufirst=Jessica&rft.date=2014-09-01&rft.volume=88&rft.issue=17&rft.spage=9647&rft.isbn=&rft.btitle=&rft.title=Journal+of+Virology&rft.issn=0022538X&rft_id=info:doi/10.1128%2FJVI.01067-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Number of references - 27 N1 - Last updated - 2015-04-02 N1 - SubjectsTermNotLitGenreText - Aerosols; Eye; Replication; Tropism; Pathogens; Infection; Public health; Models; Influenza; Virulence; Respiratory tract diseases; Infectivity; Inoculation; Inoculum; Occupational exposure; Mammals; Viruses; Vulnerability; Respiratory tract; Influenza virus; Mustela DO - http://dx.doi.org/10.1128/JVI.01067-14 ER - TY - JOUR T1 - Evaluation of the Effect of Host Immune Status on Short-Term Yersinia pestis Infection in Fleas With Implications for the Enzootic Host Model for Maintenance of Y. pestis During Interepizootic Periods AN - 1566838193; 20736299 AB - Plague, a primarily flea-borne disease caused by Yersinia pestis, is characterized by rapidly spreading epizootics separated by periods of quiescence. Little is known about how and where Y. pestis persists between epizootics. It is commonly proposed, however, that Y. pestis is maintained during interepizootic periods in enzootic cycles involving flea vectors and relatively resistant host populations. According to this model, while susceptible individuals serve as infectious sources for feeding fleas and subsequently die of infection, resistant hosts survive infection, develop antibodies to the plague bacterium, and continue to provide bloodmeals to infected fleas. For Y. pestis to persist under this scenario, fleas must remain infected after feeding on hosts carrying antibodies to Y. pestis. Studies of other vector-borne pathogens suggest that host immunity may negatively impact pathogen survival in the vector. Here, we report infection rates and bacterial loads for fleas (both Xenopsylla cheopis (Rothschild) and Oropsylla montana (Baker)) that consumed an infectious bloodmeal and subsequently fed on an immunized or age-matched naive mouse. We demonstrate that neither the proportion of infected fleas nor the bacterial loads in infected fleas were significantly lower within 3 d of feeding on immunized versus naive mice. Our findings thus provide support for one assumption underlying the enzootic host model of interepizootic maintenance of Y. Pestis. JF - Journal of Medical Entomology AU - Graham, Christine B AU - Woods, Michael E AU - Vetter, Sara M AU - Petersen, Jeannine M AU - Montenieri, John A AU - Holmes, Jennifer L AU - Maes, Sarah E AU - Bearden, Scott W AU - Gage, kenneth L AU - Eisen, Rebecca J AD - Bacterial Diseases Branch, Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, 3156 Rampart Road, Fort Collins, CO 80521, hyb4@cdc.gov Y1 - 2014/09// PY - 2014 DA - Sep 2014 SP - 1079 EP - 1086 PB - Entomological Society of America, 9301 Annapolis Rd. Lanham MD 20706 United States VL - 51 IS - 5 SN - 0022-2585, 0022-2585 KW - Microbiology Abstracts B: Bacteriology; Entomology Abstracts KW - Yersinia pestis KW - plague KW - flea KW - enzootic KW - Immune status KW - Feeding KW - Spreading KW - Animal models KW - Survival KW - Vectors KW - Epizootics KW - Immunity KW - Pathogens KW - Infection KW - Models KW - Xenopsylla cheopis KW - Antibodies KW - Plague KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - J 02350:Immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1566838193?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Medical+Entomology&rft.atitle=Evaluation+of+the+Effect+of+Host+Immune+Status+on+Short-Term+Yersinia+pestis+Infection+in+Fleas+With+Implications+for+the+Enzootic+Host+Model+for+Maintenance+of+Y.+pestis+During+Interepizootic+Periods&rft.au=Graham%2C+Christine+B%3BWoods%2C+Michael+E%3BVetter%2C+Sara+M%3BPetersen%2C+Jeannine+M%3BMontenieri%2C+John+A%3BHolmes%2C+Jennifer+L%3BMaes%2C+Sarah+E%3BBearden%2C+Scott+W%3BGage%2C+kenneth+L%3BEisen%2C+Rebecca+J&rft.aulast=Graham&rft.aufirst=Christine&rft.date=2014-09-01&rft.volume=51&rft.issue=5&rft.spage=1079&rft.isbn=&rft.btitle=&rft.title=Journal+of+Medical+Entomology&rft.issn=00222585&rft_id=info:doi/10.1603%2FME12236 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Number of references - 54 N1 - Last updated - 2015-08-05 N1 - SubjectsTermNotLitGenreText - Immune status; Feeding; Spreading; Animal models; Vectors; Survival; Epizootics; Pathogens; Immunity; Infection; Models; Antibodies; Plague; Xenopsylla cheopis; Yersinia pestis DO - http://dx.doi.org/10.1603/ME12236 ER - TY - JOUR T1 - CDC Pregnancy Flu Line: Monitoring Severe Illness Among Pregnant Women with Influenza AN - 1566831045; 20672283 AB - The Centers for Disease Control and Prevention implemented the Pregnancy Flu Line (PFL) during the influenza A(H1N1)pdm09 (pH1N1) pandemic and continued operation through the 2010-2011 influenza season to collect reports of intensive care unit (ICU) admissions and deaths among pregnant women with influenza. The system documented the severe impact of influenza on pregnant women during both seasons with 181 ICU/survivals and 37 deaths reported during the 2009 fall pandemic wave and 69 ICU/survivals and ten deaths reported in the subsequent influenza season (2010-2011). A health department survey suggests PFL participants perceived public health benefits and minimum time burdens. JF - Maternal and Child Health Journal AU - Ailes, Elizabeth C AU - Newsome, Kimberly AU - Williams, Jennifer L AU - McIntyre, Anne F AU - Jamieson, Denise J AU - Finelli, Lyn AU - Honein, Margaret A AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention (CDC), 1600 Clifton Road, MS E-86, Atlanta, GA, 30333, USA, kan3@cdc.gov Y1 - 2014/09// PY - 2014 DA - Sep 2014 SP - 1578 EP - 1582 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 18 IS - 7 SN - 1092-7875, 1092-7875 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Mortality KW - Disease control KW - Survival KW - Pregnancy KW - Public health KW - Influenza KW - Prevention KW - pandemics KW - Intensive care units KW - Perception KW - Waves KW - Females KW - H 12000:Epidemiology and Public Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1566831045?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Maternal+and+Child+Health+Journal&rft.atitle=CDC+Pregnancy+Flu+Line%3A+Monitoring+Severe+Illness+Among+Pregnant+Women+with+Influenza&rft.au=Ailes%2C+Elizabeth+C%3BNewsome%2C+Kimberly%3BWilliams%2C+Jennifer+L%3BMcIntyre%2C+Anne+F%3BJamieson%2C+Denise+J%3BFinelli%2C+Lyn%3BHonein%2C+Margaret+A&rft.aulast=Ailes&rft.aufirst=Elizabeth&rft.date=2014-09-01&rft.volume=18&rft.issue=7&rft.spage=1578&rft.isbn=&rft.btitle=&rft.title=Maternal+and+Child+Health+Journal&rft.issn=10927875&rft_id=info:doi/10.1007%2Fs10995-013-1415-6 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Number of references - 12 N1 - Last updated - 2014-12-11 N1 - SubjectsTermNotLitGenreText - Influenza; pandemics; Intensive care units; Disease control; Survival; Waves; Public health; Pregnancy; Mortality; Prevention; Perception; Females DO - http://dx.doi.org/10.1007/s10995-013-1415-6 ER - TY - JOUR T1 - Differences in risk factors for second and third degree hypospadias in the national birth defects prevention study. AN - 1563993339; 25181604 AB - Hypospadias is a frequent birth defect with three phenotypic subtypes. With data from the National Birth Defects Prevention Study, a large, multi-state, population-based, case-control study, we compared risk factors for second and third degree hypospadias. A wide variety of data on maternal and pregnancy-related risk factors for isolated second and third degree hypospadias was collected by means of computer-assisted telephone interviews to identify potential etiological differences between the two phenotypes. Logistic regression was used to calculate odds ratios including a random effect by study center. In total, 1547 second degree cases, 389 third degree cases, and 5183 male controls were included in our study. Third degree cases were more likely to have a non-Hispanic black or Asian/Pacific Islander mother, be delivered preterm, have a low birth weight, be small for gestational age, and be conceived with fertility treatments than second degree cases and controls. Associations with both second and third degree hypospadias were observed for maternal age, family history, parity, plurality, and hypertension during pregnancy. Risk estimates were generally higher for third degree hypospadias except for family history. Most risk factors were associated with both or neither phenotype. Therefore, it is likely that the underlying mechanism is at least partly similar for both phenotypes. However, some associations were different between second and third degree hypospadias, and went in opposite directions for second and third degree hypospadias for Asian/Pacific Islander mothers. Effect estimates for subtypes of hypospadias may be over- or underestimated in studies without stratification by phenotype. © 2014 Wiley Periodicals, Inc. JF - Birth defects research. Part A, Clinical and molecular teratology AU - Woud, Sander Groen In 't AU - van Rooij, Iris A L M AU - van Gelder, Marleen M H J AU - Olney, Richard S AU - Carmichael, Suzan L AU - Roeleveld, Nel AU - Reefhuis, Jennita AU - National Birth Defects Prevention Study AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia; Department for Health Evidence, Radboud university medical center, Nijmegen, The Netherlands. ; National Birth Defects Prevention Study Y1 - 2014/09// PY - 2014 DA - September 2014 SP - 703 EP - 711 VL - 100 IS - 9 KW - Index Medicus KW - pregnancy KW - birth defects KW - hypospadias KW - risk factors KW - Netherlands -- epidemiology KW - Odds Ratio KW - Infant, Low Birth Weight KW - Humans KW - Oceanic Ancestry Group KW - Infant, Newborn KW - Infant, Premature KW - Pregnancy KW - Phenotype KW - Asian Continental Ancestry Group KW - Logistic Models KW - Risk Factors KW - Adult KW - Health Surveys KW - Case-Control Studies KW - United States -- epidemiology KW - Female KW - Male KW - Hypospadias -- classification KW - Hypertension, Pregnancy-Induced -- ethnology KW - Hypospadias -- ethnology KW - Hypertension, Pregnancy-Induced -- epidemiology KW - Hypospadias -- epidemiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1563993339?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Birth+defects+research.+Part+A%2C+Clinical+and+molecular+teratology&rft.atitle=Differences+in+risk+factors+for+second+and+third+degree+hypospadias+in+the+national+birth+defects+prevention+study.&rft.au=Woud%2C+Sander+Groen+In+%27t%3Bvan+Rooij%2C+Iris+A+L+M%3Bvan+Gelder%2C+Marleen+M+H+J%3BOlney%2C+Richard+S%3BCarmichael%2C+Suzan+L%3BRoeleveld%2C+Nel%3BReefhuis%2C+Jennita%3BNational+Birth+Defects+Prevention+Study&rft.aulast=Woud&rft.aufirst=Sander+Groen+In&rft.date=2014-09-01&rft.volume=100&rft.issue=9&rft.spage=703&rft.isbn=&rft.btitle=&rft.title=Birth+defects+research.+Part+A%2C+Clinical+and+molecular+teratology&rft.issn=1542-0760&rft_id=info:doi/10.1002%2Fbdra.23296 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2015-05-21 N1 - Date created - 2014-09-19 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Cited By: Birth Defects Res A Clin Mol Teratol. 2012 Jul;94(7):499-510 [22678668] Public Health Rep. 2001;116 Suppl 1:32-40 [11889273] J Urol. 2002 Mar;167(3):1423-7 [11832761] BJU Int. 2013 Jul;112(1):121-8 [23305310] Birth Defects Res A Clin Mol Teratol. 2003 Mar;67(3):193-201 [12797461] Epidemiology. 2003 Nov;14(6):701-6 [14569186] Placenta. 2004 Feb-Mar;25(2-3):127-39 [14972445] J Urol. 1979 Apr;121(4):474-7 [439223] J Med Genet. 1990 Sep;27(9):559-63 [2231648] Epidemiol Rev. 1990;12:29-40 [2286224] Obstet Gynecol. 1996 Feb;87(2):163-8 [8559516] Pediatrics. 1997 Nov;100(5):831-4 [9346983] J Urol. 1998 Dec;160(6 Pt 1):2197-9 [9817368] Environ Health Perspect. 1999 Apr;107(4):297-302 [10090709] J Androl. 2005 Mar-Apr;26(2):163-8 [15713818] Pediatrics. 2005 Apr;115(4):e495-9 [15741350] J Urol. 2005 Oct;174(4 Pt 2):1544-8; discussion 1548 [16148649] Birth Defects Res A Clin Mol Teratol. 2006 Apr;76(4):249-52 [16586447] Paediatr Perinat Epidemiol. 2007 May;21(3):210-8 [17439529] Eur J Pediatr. 2007 Jul;166(7):671-8 [17103190] Birth Defects Res A Clin Mol Teratol. 2008 Jan;82(1):34-40 [18022875] Am J Epidemiol. 2008 Feb 1;167(3):251-6 [18042671] J Pediatr Psychol. 2008 Jun;33(5):520-35 [18056145] Environ Health Perspect. 2008 Aug;116(8):1071-6 [18709149] Birth Defects Res A Clin Mol Teratol. 2009 Jul;85(7):621-8 [19215015] Am J Med Genet A. 2010 Jan;152A(1):75-83 [20014131] BJU Int. 2010 Jan;105(2):254-62 [19751252] Hum Reprod. 2011 Feb;26(2):451-7 [21112952] Urology. 2011 Mar;77(3):716-20 [20970827] Hum Reprod Update. 2012 May-Jun;18(3):260-83 [22371315] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1002/bdra.23296 ER - TY - JOUR T1 - Nocardia vulneris sp. nov., isolated from wounds of human patients in North America AN - 1560120013; 20528095 AB - Nocardia species are ubiquitous in the environment with an increasing number of species isolated from clinical sources. From 2005 to 2009, eight isolates (W9042, W9247, W9290, W9319, W9846, W9851 super(T), W9865, and W9908) were obtained from eight patients from three states in the United States and Canada; all were from males ranging in age from 47 to 81 years old; and all were obtained from finger (n = 5) or leg (n = 3) wounds. Isolates were characterized by polyphasic analysis using molecular, phenotypic, morphologic and chemotaxonomic methods. Sequence analysis of 16S rRNA gene sequences showed the eight isolates are 100 % identical to each other and belong in the genus Nocardia. The nearest phylogenetically related neighbours were found to be the type strains for Nocardia altamirensis (99.33 % sequence similarity), Nocardia brasiliensis (99.37 %), Nocardia iowensis (98.95 %) and Nocardia tenerifensis (98.44 %). The G+C content of isolate W9851 super(T) was determined to be 68.4 mol %. The DNA-DNA relatedness between strain W9851 super(T) and the N. brasiliensis type strain was 72.8 % and 65.8 % when measured in the laboratory and in silico from genome sequences, respectively, and 95.6 % ANI. Whole-cell peptidoglycan was found to contain meso-diaminopimelic acid; MK-8-(H sub(4)) sub( omega -cyc) was identified as the major menaquinone; the major fatty acids were identified as C sub(16:0), 10 Me C sub(18:0), and C sub(18:1 w9c), the predominant phospholipids were found to include diphosphatidylglycerol, phosphatidylethanolamine, phosphatidylinositol and phosphatidylinositol mannosides; whole-cell sugars detected were arabinose and galactose; and mycolic acids ranging from 38 to 60 carbon atoms were found to be present. These chemotaxonomic analyses are consistent with assignment of the isolates to the genus Nocardia. Matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectra of the clinical isolates showed genus and species level profiles that were different from other Nocardia species. All isolates were resistant to ciprofloxacin, clarithromycin and imipenem but were susceptible to amikacin, amoxicillin/clavulanate, linezolid and trimethoprim/sulfamethoxazole. The results of our polyphasic analysis suggest the new isolates obtained from wound infections represent a novel species within the genus Nocardia, for which the name Nocardia vulneris sp. nov. is proposed, with strain W9851 super(T) (= DSM 45737 super(T) = CCUG 62683 super(T) = NBRC 108936 super(T)) as the type strain. JF - Antonie Van Leeuwenhoek AU - Lasker, Brent A AU - Bell, Melissa AU - Klenk, Hans-Peter AU - Sproer, Cathrin AU - Schumann, Peter AU - Brown, June M AD - Bacterial Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Disease, Centers for Disease Control and Prevention, Building 17, Room 2025, Mailstop G-11, 1600 Clifton Road, Atlanta, GA, 30333, USA, blasker@cdc.gov Y1 - 2014/09// PY - 2014 DA - September 2014 SP - 543 EP - 553 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 106 IS - 3 SN - 0003-6072, 0003-6072 KW - Microbiology Abstracts B: Bacteriology KW - Galactose KW - Trimethoprim KW - Age KW - Amikacin KW - phosphatidylinositol KW - Diphosphatidylglycerol KW - peptidoglycans KW - Mycolic acids KW - Flight KW - Ciprofloxacin KW - Clarithromycin KW - Carbon KW - Linezolid KW - Phospholipids KW - Clinical isolates KW - Phylogeny KW - Sugar KW - Amoxicillin KW - Sulfamethoxazole KW - Nocardia brasiliensis KW - Wounds KW - Finger KW - Imipenem KW - Leg KW - Menaquinones KW - Wound infection KW - Fatty acids KW - Lasers KW - phosphatidylethanolamine KW - rRNA 16S KW - New species KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1560120013?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antonie+Van+Leeuwenhoek&rft.atitle=Nocardia+vulneris+sp.+nov.%2C+isolated+from+wounds+of+human+patients+in+North+America&rft.au=Lasker%2C+Brent+A%3BBell%2C+Melissa%3BKlenk%2C+Hans-Peter%3BSproer%2C+Cathrin%3BSchumann%2C+Peter%3BBrown%2C+June+M&rft.aulast=Lasker&rft.aufirst=Brent&rft.date=2014-09-01&rft.volume=106&rft.issue=3&rft.spage=543&rft.isbn=&rft.btitle=&rft.title=Antonie+Van+Leeuwenhoek&rft.issn=00036072&rft_id=info:doi/10.1007%2Fs10482-014-0226-0 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Number of references - 40 N1 - Last updated - 2016-08-03 N1 - SubjectsTermNotLitGenreText - Galactose; Age; Trimethoprim; Amikacin; phosphatidylinositol; Diphosphatidylglycerol; peptidoglycans; Mycolic acids; Flight; Clarithromycin; Ciprofloxacin; Carbon; Linezolid; Phospholipids; Phylogeny; Clinical isolates; Sugar; Amoxicillin; Sulfamethoxazole; Imipenem; Finger; Wounds; Leg; Wound infection; Menaquinones; Fatty acids; Lasers; phosphatidylethanolamine; rRNA 16S; New species; Nocardia brasiliensis DO - http://dx.doi.org/10.1007/s10482-014-0226-0 ER - TY - JOUR T1 - Developing a systematic approach to safer medication use during pregnancy: summary of a Centers for Disease Control and Prevention--convened meeting. AN - 1558526278; 24881821 AB - To address information gaps that limit informed clinical decisions on medication use in pregnancy, the Centers for Disease Control and Prevention (CDC) solicited expert input on a draft prototype outlining a systematic approach to evaluating the quality and strength of existing evidence for associated risks. The draft prototype outlined a process for the systematic review of available evidence and deliberations by a panel of experts to inform clinical decision making for managing health conditions in pregnancy. At an expert meeting convened by the CDC in January 2013, participants divided into working groups discussed decision points within the prototype. This report summarizes their discussions of best practices for formulating an expert review process, developing evidence summaries and treatment guidance, and disseminating information. There is clear recognition of current knowledge gaps and a strong collaboration of federal partners, academic experts, and professional organizations willing to work together toward safer medication use during pregnancy. Published by Elsevier Inc. JF - American journal of obstetrics and gynecology AU - Broussard, Cheryl S AU - Frey, Meghan T AU - Hernandez-Diaz, Sonia AU - Greene, Michael F AU - Chambers, Christina D AU - Sahin, Leyla AU - Collins Sharp, Beth A AU - Honein, Margaret A AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA. Electronic address: cbroussard@cdc.gov. ; National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA; Oak Ridge Institute for Science and Education, Oak Ridge, TN. ; Harvard School of Public Health, Boston, MA. ; Department of Obstetrics, Gynecology, and Reproductive Biology, Harvard Medical School and Massachusetts General Hospital, Boston, MA. ; Departments of Pediatrics and Family and Preventive Medicine, University of California, San Diego, La Jolla, CA. ; Pediatric and Maternal Health Staff, Maternal Health Team, Office of New Drugs, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, MD. ; Agency for Healthcare Research and Quality, Rockville, MD. ; National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA. Y1 - 2014/09// PY - 2014 DA - September 2014 SP - 208 EP - 214.e1 VL - 211 IS - 3 KW - Abridged Index Medicus KW - Index Medicus KW - teratogens KW - medications KW - Centers for Disease Control and Prevention KW - pregnancy KW - expert review KW - United States KW - Animals KW - Centers for Disease Control and Prevention (U.S.) KW - Humans KW - Safety KW - Practice Guidelines as Topic KW - Female KW - Pregnancy KW - Fetus -- drug effects KW - Pregnancy Complications -- drug therapy KW - Abnormalities, Drug-Induced -- prevention & control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1558526278?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+journal+of+obstetrics+and+gynecology&rft.atitle=Developing+a+systematic+approach+to+safer+medication+use+during+pregnancy%3A+summary+of+a+Centers+for+Disease+Control+and+Prevention--convened+meeting.&rft.au=Broussard%2C+Cheryl+S%3BFrey%2C+Meghan+T%3BHernandez-Diaz%2C+Sonia%3BGreene%2C+Michael+F%3BChambers%2C+Christina+D%3BSahin%2C+Leyla%3BCollins+Sharp%2C+Beth+A%3BHonein%2C+Margaret+A&rft.aulast=Broussard&rft.aufirst=Cheryl&rft.date=2014-09-01&rft.volume=211&rft.issue=3&rft.spage=208&rft.isbn=&rft.btitle=&rft.title=American+journal+of+obstetrics+and+gynecology&rft.issn=1097-6868&rft_id=info:doi/10.1016%2Fj.ajog.2014.05.040 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2014-10-22 N1 - Date created - 2014-08-29 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Cited By: Teratology. 1994 Jun;49(6):446-7 [7747265] J Womens Health (Larchmt). 2005 Mar;14(2):104-9 [15775727] Clin Perinatol. 2005 Sep;32(3):523-59 [16085019] Best Pract Res Clin Gastroenterol. 2007;21(5):755-69 [17889806] MMWR Surveill Summ. 2007 Dec 14;56(10):1-35 [18075488] Clin Pharmacol Ther. 2008 Jan;83(1):181-3 [18073777] BMJ. 2008 Apr 26;336(7650):924-6 [18436948] Med Ref Serv Q. 2008 Spring;27(1):73-80 [18689204] Ann Intern Med. 2009 Jan 6;150(1):45-9 [19124820] Birth Defects Res A Clin Mol Teratol. 2009 Feb;85(2):137-50 [19161158] Birth Defects Res A Clin Mol Teratol. 2009 Mar;85(3):193-201 [19086018] Curr Pain Headache Rep. 2009 Oct;13(5):392-8 [19728967] Ann Pharmacother. 2010 Mar;44(3):456-61 [20164469] Birth. 2010 Jun;37(2):106-15 [20557533] MMWR Recomm Rep. 2010 Nov 19;59(RR-10):1-36 [21088663] MMWR Recomm Rep. 2010 Dec 17;59(RR-12):1-110 [21160459] Obstet Gynecol. 2011 Apr;117(4):1019-27 [21422882] Am J Med Genet C Semin Med Genet. 2011 Aug 15;157C(3):175-82 [21766440] Vaccine. 2011 Nov 15;29(49):9171-6 [21839794] Am J Obstet Gynecol. 2011 Jul;205(1):51.e1-8 [21514558] Pediatrics. 2011 Sep;128(3):611-6 [21807694] Hum Reprod Update. 2012 Jul;18(4):360-73 [22431565] J Womens Health (Larchmt). 2012 Aug;21(8):830-6 [22691031] Birth Defects Res A Clin Mol Teratol. 2012 Aug;94(8):670-6 [22786781] Pharmacoepidemiol Drug Saf. 2013 Sep;22(9):1013-8 [23893932] Fed Regist. 2014 Dec 4;79(233):72063-103 [25509060] Comment In: Am J Obstet Gynecol. 2015 Jul;213(1):116 [25557207] Am J Obstet Gynecol. 2015 Jul;213(1):115-6 [25555661] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1016/j.ajog.2014.05.040 ER - TY - JOUR T1 - Attrition of MSM with HIV/AIDS along the continuum of care from screening to CD4 testing in China AN - 1548778387; 4583148 AB - The aim of this study is to describe attrition of newly diagnosed men who have sex with men (MSM) living with HIV/AIDS from screening to CD4 testing and provide suggestions to improve HIV case management in China. Data from 15 China-Gates Program project cities were collected on number of MSM who underwent each step from HIV screening to CD4 testing. Descriptive statistics were calculated. A total of 76,628 HIV screening tests were performed among MSM, of which 4563 were HIV-positive. Most attrition occurred at confirmatory and CD4 testing. Within the same year, 21% (1065/4063) of MSM who screened HIV-positive did not receive confirmatory testing and 34% (1025/3024) of MSM newly diagnosed with HIV/AIDS did not receive CD4 testing. Marked differences were observed between project areas in attrition at these points of the care continuum. Marked differences were also observed across areas in the rate of CD4 counts <350 cells/mcl, ranging from 23% to 87%. In the current process for diagnosis and management of HIV infection in China, many MSM are lost to follow-up at HIV confirmation and CD4 testing. Actions should be taken to reduce complexity and time lag from screening to CD4 test and emphasize the importance of remaining in care during posttest counseling. Reprinted by permission of Routledge, Taylor & Francis Ltd. JF - AIDS care AU - Zhang, Dapeng AU - Li, Chengmei AU - Meng, Sining AU - Qi, Jinlei AU - Fu, Xiaojing AU - Sun, Jiangping AD - Chinese Center for Disease Control and Prevention Y1 - 2014/09// PY - 2014 DA - Sep 2014 SP - 1118 EP - 1121 VL - 26 IS - 9 SN - 0954-0121, 0954-0121 KW - Sociology KW - Sexual behaviour KW - Health care KW - AIDS KW - China KW - Public health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1548778387?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+care&rft.atitle=Attrition+of+MSM+with+HIV%2FAIDS+along+the+continuum+of+care+from+screening+to+CD4+testing+in+China&rft.au=Zhang%2C+Dapeng%3BLi%2C+Chengmei%3BMeng%2C+Sining%3BQi%2C+Jinlei%3BFu%2C+Xiaojing%3BSun%2C+Jiangping&rft.aulast=Zhang&rft.aufirst=Dapeng&rft.date=2014-09-01&rft.volume=26&rft.issue=9&rft.spage=1118&rft.isbn=&rft.btitle=&rft.title=AIDS+care&rft.issn=09540121&rft_id=info:doi/10.1080%2F09540121.2014.902420 LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2014-07-28 N1 - Last updated - 2014-07-29 N1 - SubjectsTermNotLitGenreText - 482 3617 6220; 11563 1025 1542 11325 6071; 10449 5772; 5775 13521; 93 116 30 DO - http://dx.doi.org/10.1080/09540121.2014.902420 ER - TY - JOUR T1 - Incidence and associated factors of pulmonary tuberculosis in HIV-infected children after highly active antiretroviral therapy (HAART) in China: a retrospective study AN - 1548775883; 4583137 AB - China is a country with high tuberculosis (TB) incidence but relatively low HIV prevalence. However, due to difficulties in diagnosis and reporting, true burden of HIV-associated TB in children is unknown. The objective of this study was to describe the incidence of pulmonary TB (PTB) after antiretroviral therapy (ART) and to study risk factors. A retrospective study was performed based on routinely collected data from China national pediatric free antiretroviral treatment database. A total of 3365 children under 15 years on ART from July 2005 to October 2012 were included. Multivariable logistic regression was used to detect associated factors. Two thousand nine hundred and ninety (89%) children got infected from HIV-positive mother, with median age of 6.7 (4.1, 10.0) years at highly active antiretroviral therapy (HAART) initiation in this program. Seventy-seven (2.3%) children were diagnosed with PTB after ART during 7.3 years cohort observation. Median time of occurrence was 212 (30-514) days. Overall incidence was 0.83 (0.65-1.01)/100 person-years (py), with the peak of 3.6/100 py in the first 3 months after antiretroviral treatment. WHO stage IV at baseline showed 2 (95% CI 1.0-6.8) times more risk for developing TB. Late clinical stage at ART initiation was shown to relate with TB incidence. PTB coinfection leads to higher mortality. Early diagnosis and treatment of HIV are highly required to reduce HIV-associated morbidity and mortality due to TB. Reprinted by permission of Routledge, Taylor & Francis Ltd. JF - AIDS care AU - Mu, Weiwei AU - Zhao, Yan AU - Sun, Xin AU - Ma, Ye AU - Yu, Lan AU - Liu, Xia AU - Zhao, Decai AU - Dou, Zhihui AU - Fang, Hua AU - Zhang, Fujie AD - Chinese Center For Disease Control And Prevention Y1 - 2014/09// PY - 2014 DA - Sep 2014 SP - 1127 EP - 1135 VL - 26 IS - 9 SN - 0954-0121, 0954-0121 KW - Sociology KW - Risk KW - Mortality KW - Medical treatment KW - Tuberculosis KW - HIV KW - China UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1548775883?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+care&rft.atitle=Incidence+and+associated+factors+of+pulmonary+tuberculosis+in+HIV-infected+children+after+highly+active+antiretroviral+therapy+%28HAART%29+in+China%3A+a+retrospective+study&rft.au=Mu%2C+Weiwei%3BZhao%2C+Yan%3BSun%2C+Xin%3BMa%2C+Ye%3BYu%2C+Lan%3BLiu%2C+Xia%3BZhao%2C+Decai%3BDou%2C+Zhihui%3BFang%2C+Hua%3BZhang%2C+Fujie&rft.aulast=Mu&rft.aufirst=Weiwei&rft.date=2014-09-01&rft.volume=26&rft.issue=9&rft.spage=1127&rft.isbn=&rft.btitle=&rft.title=AIDS+care&rft.issn=09540121&rft_id=info:doi/10.1080%2F09540121.2014.882492 LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2014-07-28 N1 - Last updated - 2014-07-29 N1 - SubjectsTermNotLitGenreText - 13020 3617 6220; 8291 3409 6306; 5703 3617 6220; 7890 5792 10484; 11035; 93 116 30 DO - http://dx.doi.org/10.1080/09540121.2014.882492 ER - TY - JOUR T1 - Oxidative stress and reduced responsiveness of challenged circulating leukocytes following pulmonary instillation of metal-rich particulate matter in rats. AN - 1560095504; 25123171 AB - Welding fume is an exposure that consists of a mixture of metal-rich particulate matter with gases (ozone, carbon monoxide) and/or vapors (VOCs). Data suggests that welders are immune compromised. Given the inability of pulmonary leukocytes to properly respond to a secondary infection in animal models, the question arose whether the dysfunction persisted systemically. Our aim was to evaluate the circulating leukocyte population in terms of cellular activation, presence of oxidative stress, and functionality after a secondary challenge, following welding fume exposure. Rats were intratracheally instilled (ITI) with PBS or 2 mg of welding fume collected from a stainless steel weld. Rats were sacrificed 4 and 24 h post-exposure and whole blood was collected. Whole blood was used for cellular differential counts, RNA isolation with subsequent microarray and Ingenuity Pathway Analysis, and secondary stimulation with LPS utilizing TruCulture technology. In addition, mononuclear cells were isolated 24 h post-exposure to measure oxidative stress by flow cytometry and confocal microscopy. Welding fume exposure had rapid effects on the circulating leukocyte population as identified by relative mRNA expression changes. Instillation of welding fume reduced inflammatory protein production of circulating leukocytes when challenged with the secondary stimulus LPS. The effects were not related to transcription, but were observed in conjunction with oxidative stress. These findings support previous studies of an inadequate pulmonary immune response following a metal-rich exposure and extend those findings showing leukocyte dysfunction occurs systemically. JF - Particle and fibre toxicology AU - Erdely, Aaron AU - Antonini, James M AU - Young, Shih-Houng AU - Kashon, Michael L AU - Gu, Ja K AU - Hulderman, Tracy AU - Salmen, Rebecca AU - Meighan, Terence AU - Roberts, Jenny R AU - Zeidler-Erdely, Patti C AD - Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown 26505, WV, USA. efi4@cdc.gov. Y1 - 2014/08/15/ PY - 2014 DA - 2014 Aug 15 SP - 34 VL - 11 KW - Inflammation Mediators KW - 0 KW - Lipopolysaccharides KW - Particulate Matter KW - RNA, Messenger KW - Stainless Steel KW - 12597-68-1 KW - Index Medicus KW - Animals KW - Oligonucleotide Array Sequence Analysis KW - Lipopolysaccharides -- pharmacology KW - Transcription, Genetic KW - Gene Expression Profiling -- methods KW - Inflammation Mediators -- metabolism KW - Rats, Sprague-Dawley KW - RNA, Messenger -- metabolism KW - Cells, Cultured KW - Gene Expression Regulation KW - Immunocompromised Host KW - Time Factors KW - Male KW - Particulate Matter -- toxicity KW - Leukocytes -- metabolism KW - Leukocytes -- immunology KW - Stainless Steel -- toxicity KW - Oxidative Stress -- drug effects KW - Welding KW - Leukocytes -- drug effects KW - Inhalation Exposure -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1560095504?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Particle+and+fibre+toxicology&rft.atitle=Oxidative+stress+and+reduced+responsiveness+of+challenged+circulating+leukocytes+following+pulmonary+instillation+of+metal-rich+particulate+matter+in+rats.&rft.au=Erdely%2C+Aaron%3BAntonini%2C+James+M%3BYoung%2C+Shih-Houng%3BKashon%2C+Michael+L%3BGu%2C+Ja+K%3BHulderman%2C+Tracy%3BSalmen%2C+Rebecca%3BMeighan%2C+Terence%3BRoberts%2C+Jenny+R%3BZeidler-Erdely%2C+Patti+C&rft.aulast=Erdely&rft.aufirst=Aaron&rft.date=2014-08-15&rft.volume=11&rft.issue=&rft.spage=34&rft.isbn=&rft.btitle=&rft.title=Particle+and+fibre+toxicology&rft.issn=1743-8977&rft_id=info:doi/10.1186%2Fs12989-014-0034-8 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2015-03-30 N1 - Date created - 2014-09-03 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Cited By: J Toxicol Environ Health A. 1999 Nov 26;58(6):343-63 [10580758] Part Fibre Toxicol. 2012;9:25 [22776377] Am J Epidemiol. 2003 Feb 1;157(3):227-33 [12543622] Toxicol Sci. 2003 Sep;75(1):181-91 [12832661] Toxicol Appl Pharmacol. 2004 Nov 1;200(3):206-18 [15504457] Lancet. 1994 Jul 2;344(8914):41-3 [7912307] Toxicol Appl Pharmacol. 1998 Sep;152(1):30-40 [9772197] Occup Environ Med. 2005 Mar;62(3):157-63 [15723880] Cancer Epidemiol Biomarkers Prev. 2005 May;14(5):1340-3 [15894700] Mutagenesis. 2005 Sep;20(5):311-5 [15985443] Mol Cell Biochem. 2005 Nov;279(1-2):17-23 [16283511] Environ Health Perspect. 2006 Mar;114(3):412-9 [16507465] Physiol Genomics. 2006 Apr 13;25(2):203-15 [16403844] J Biol Chem. 2006 Sep 29;281(39):29011-21 [16849329] Toxicol Appl Pharmacol. 2007 Sep 15;223(3):234-45 [17706736] Epidemiology. 2008 Mar;19(2):217-25 [18300696] Nano Lett. 2009 Jan;9(1):36-43 [19049393] Inhal Toxicol. 2009 Feb;21(3):182-92 [18925477] Environ Toxicol. 2009 Feb;24(1):66-73 [18508361] J Occup Environ Hyg. 2010 Jun;7(6):367-74 [20397091] Respir Res. 2010;11:70 [20525249] Toxicol Lett. 2011 Jul 4;204(1):12-6 [21513782] J Occup Environ Med. 2011 Jun;53(6 Suppl):S80-6 [21654424] Toxicology. 2011 Sep 5;287(1-3):153-9 [21708214] J Immunotoxicol. 2012 Apr-Jun;9(2):184-92 [22369286] Occup Med (Lond). 2012 Jul;62(5):325-30 [22764269] J Immunotoxicol. 2012 Oct-Dec;9(4):411-25 [22734811] Toxicol Sci. 2002 Nov;70(1):110-9 [12388840] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1186/s12989-014-0034-8 ER - TY - JOUR T1 - Increasing Rates of Prenatal Testing among Jewish and Arab Women in Israel over One Decade AN - 1773837880; PQ0002707966 AB - Background/Aims/Objective: This study compared data on the use of prenatal tests offered to pregnant women in Israel as reported in a national survey conducted by the Israel Center for Disease Control in 2001 to data from 2010. Methods: Mothers of newborns were interviewed 8-72 h after delivery in 29 maternity wards in Israel on May 31, 2010. Results: A total of 768 women were interviewed, 569 (72.3%) were Jewish and 197 (25.7%) were Arabs. Nuchal translucency screening and early ultrasound level 2 were significantly more frequently done in both Jewish and Arab women in 2010 than in 2001. The use of the biochemical triple marker test and amniocentesis did not change. The increased rate of nuchal translucency screening and early ultrasound level 2 was significantly higher among the Jewish women compared to the Arabs (21.5 and 28.0% vs. 2.9 and 13.7% in 2001; 62.0 and 65.6% vs. 30.1 and 30.9% in 2010, respectively). The rates of amniocentesis in the Jewish women aged 35 years were 47.6 and 47.5% in 2001 and 2010, respectively; they are significantly higher than among the Arabs (18.5 and 28.5%, respectively). The factors associated with making more use of different prenatal tests were: secularity, a higher income, and supplementary medical insurance for the Jewish women, and supplementary medical insurance and printed information on prenatal testing for the Arabs. Conclusions: The prenatal testing rates have risen over the last decade in both population groups, but there are still significant gaps. We suggest that public funding of additional prenatal tests may increase their use in both population groups. copyright 2014 S. Karger AG, Basel JF - Public Health Genomics AU - Romano-Zelekha, Orly AU - Ostrovsky, Jenny AU - Shohat, Tamy AD - Israel Center for Disease Control, Ministry of Health, Ramat Gan Y1 - 2014/08// PY - 2014 DA - August 2014 SP - 183 EP - 189 PB - S. Karger AG, P.O. Box Basel CH-4009 Switzerland VL - 17 IS - 4 SN - 1662-4246, 1662-4246 KW - Genetics Abstracts; Health & Safety Science Abstracts KW - Amniocentesis KW - Arab women KW - Fetal ultrasound KW - Increased use of tests KW - Jewish women KW - Nuchal translucency screening KW - Prenatal testing KW - Prenatal experience KW - Data processing KW - Biochemistry KW - Disease control KW - Israel KW - Insurance KW - Income KW - Public health KW - Pregnancy KW - Females KW - Neonates KW - Ultrasound KW - G 07880:Human Genetics KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1773837880?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Public+Health+Genomics&rft.atitle=Increasing+Rates+of+Prenatal+Testing+among+Jewish+and+Arab+Women+in+Israel+over+One+Decade&rft.au=Romano-Zelekha%2C+Orly%3BOstrovsky%2C+Jenny%3BShohat%2C+Tamy&rft.aulast=Romano-Zelekha&rft.aufirst=Orly&rft.date=2014-08-01&rft.volume=17&rft.issue=4&rft.spage=183&rft.isbn=&rft.btitle=&rft.title=Public+Health+Genomics&rft.issn=16624246&rft_id=info:doi/10.1159%2F000362224 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-03-01 N1 - Last updated - 2016-09-14 N1 - SubjectsTermNotLitGenreText - Data processing; Amniocentesis; Disease control; Neonates; Ultrasound; Pregnancy; Public health; Prenatal experience; Biochemistry; Females; Insurance; Income; Israel DO - http://dx.doi.org/10.1159/000362224 ER - TY - JOUR T1 - Sequential Episodes of Dengue-Puerto Rico, 2005-2010 AN - 1727695448; PQ0002139999 AB - Of 53,633 suspected dengue cases reported to a passive dengue surveillance system in Puerto Rico during 2005-2010, 949 individuals were reported on more than one occasion and 21 had laboratory-confirmed dengue on two separate occasions. Median time between illness episodes was 2.9 years (range: 62 days-5.3 years). Seventeen (81%) individuals with sequential episodes of dengue were male, and seven (33%) were adults. All 21 individuals experienced one episode and seven (33%) individuals experienced both episodes during a large epidemic that occurred in 2010. These observations show that heterotypic dengue virus immunity that protects against illness may have considerable variability but typically does not last longer than 3 years. JF - American Journal of Tropical Medicine and Hygiene AU - Sharp, Tyler M AU - Hunsperger, Elizabeth AU - Munoz-Jordan, Jorge L AU - Margolis, Harold S AU - Tomashek, Kay M AD - Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, tsharp@cdc.gov Y1 - 2014/08// PY - 2014 DA - August 2014 SP - 235 EP - 239 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 91 IS - 2 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Dengue virus KW - Epidemics KW - ASW, Caribbean Sea, Greater Antilles, Puerto Rico KW - Dengue KW - Surveillance and enforcement KW - Immunity KW - Hygiene KW - K 03400:Human Diseases KW - J 02400:Human Diseases KW - Q1 08604:Stock assessment and management KW - Q5 08524:Public health, medicines, dangerous organisms KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727695448?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Sequential+Episodes+of+Dengue-Puerto+Rico%2C+2005-2010&rft.au=Sharp%2C+Tyler+M%3BHunsperger%2C+Elizabeth%3BMunoz-Jordan%2C+Jorge+L%3BMargolis%2C+Harold+S%3BTomashek%2C+Kay+M&rft.aulast=Sharp&rft.aufirst=Tyler&rft.date=2014-08-01&rft.volume=91&rft.issue=2&rft.spage=235&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.13-0742 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Epidemics; Surveillance and enforcement; Immunity; Hygiene; Dengue; Dengue virus; ASW, Caribbean Sea, Greater Antilles, Puerto Rico DO - http://dx.doi.org/10.4269/ajtmh.13-0742 ER - TY - JOUR T1 - Molecular Detection of Adenoviruses, Rhabdoviruses, and Paramyxoviruses in Bats from Kenya AN - 1727694764; PQ0002140003 AB - We screened 217 bats of at least 20 species from 17 locations in Kenya during July and August of 2006 for the presence of adenovirus, rhabdovirus, and paramyxovirus nucleic acids using generic reverse transcription polymerase chain reaction (RT-PCR) and PCR assays. Of 217 bat fecal swabs examined, 4 bats were adenovirus DNA-positive, 11 bats were paramyxovirus RNA-positive, and 2 bats were rhabdovirus RNA-positive. Three bats were coinfected by two different viruses. By sequence comparison and phylogenetic analysis, the Kenya bat paramyxoviruses and rhabdoviruses from this study may represent novel viral lineages within their respective families; the Kenya bat adenoviruses could not be confirmed as novel, because the same region sequences from other known bat adenovirus genomes for comparison were lacking. Our study adds to previous evidence that bats carry diverse, potentially zoonotic viruses and may be coinfected with more than one virus. JF - American Journal of Tropical Medicine and Hygiene AU - Conrardy, Christina AU - Tao, Ying AU - Kuzmin, Ivan V AU - Niezgoda, Michael AU - Agwanda, Bernard AU - Breiman, Robert F AU - Anderson, Larry J AU - Rupprecht, Charles E AU - Tong, Suxiang AD - Division of Viral Disease, Centers for Disease Control and Prevention, Atlanta, Georgia, sot1@cdc.gov Y1 - 2014/08// PY - 2014 DA - August 2014 SP - 258 EP - 266 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 91 IS - 2 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Phylogeny KW - Genomes KW - Nucleotide sequence KW - Viruses KW - Adenovirus KW - Transcription KW - Paramyxovirus KW - Reverse transcription KW - Kenya KW - nucleic acids KW - DNA KW - Polymerase chain reaction KW - Rhabdovirus KW - Hygiene KW - Phylogenetics KW - Nucleic acids KW - J 02310:Genetics & Taxonomy KW - Q1 08563:Fishing gear and methods KW - Q5 08504:Effects on organisms KW - K 03310:Genetics & Taxonomy KW - V 22310:Genetics, Taxonomy & Structure UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727694764?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Molecular+Detection+of+Adenoviruses%2C+Rhabdoviruses%2C+and+Paramyxoviruses+in+Bats+from+Kenya&rft.au=Conrardy%2C+Christina%3BTao%2C+Ying%3BKuzmin%2C+Ivan+V%3BNiezgoda%2C+Michael%3BAgwanda%2C+Bernard%3BBreiman%2C+Robert+F%3BAnderson%2C+Larry+J%3BRupprecht%2C+Charles+E%3BTong%2C+Suxiang&rft.aulast=Conrardy&rft.aufirst=Christina&rft.date=2014-08-01&rft.volume=91&rft.issue=2&rft.spage=258&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.13-0664 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Genomes; Nucleotide sequence; Viruses; DNA; Transcription; Polymerase chain reaction; Hygiene; Nucleic acids; Phylogenetics; Phylogeny; nucleic acids; Reverse transcription; Adenovirus; Rhabdovirus; Paramyxovirus; Kenya DO - http://dx.doi.org/10.4269/ajtmh.13-0664 ER - TY - JOUR T1 - Public Health Emergency Planning for Children in Chemical, Biological, Radiological, and Nuclear (CBRN) Disasters AN - 1709185470; 21183954 AB - Children represent nearly a guarter of the US population, but their unigue needs in chemical, biological, radiological, and nuclear (CBRN) emergencies may not be well understood by public health and emergency management personnel or even clinicians. Children are different from adults physically, developmentally, and socially. These characteristics have implications for providing care in CBRN disasters, making resulting illness in children challenging to prevent, identify, and treat. This article discusses these distinct physical, developmental, and social traits and characteristics of children in the context of the science behind exposure to, health effects from, and treatment for the threat agents potentially present in CBRN incidents. JF - Biosecurity and Bioterrorism AU - Bartenfeld, Michael T AU - Peacock, Georgina AU - Griese, Stephanie E AD - Centers for Disease Control and Prevention, National Center on Birth Defects and Developmental Disabilities, 1600 Clifton Road, MS-E86, Atlanta, GA 30333, vdv4@cdc.gov Y1 - 2014/08// PY - 2014 DA - Aug 2014 SP - 201 EP - 207 PB - Mary Ann Liebert, Inc., 2 Madison Ave Larchmont NY 10538-1962 United States VL - 12 IS - 4 SN - 1538-7135, 1538-7135 KW - Biotechnology and Bioengineering Abstracts KW - bioterrorism KW - Personnel KW - Children KW - Public health KW - W 30965:Miscellaneous, Reviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1709185470?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biosecurity+and+Bioterrorism&rft.atitle=Public+Health+Emergency+Planning+for+Children+in+Chemical%2C+Biological%2C+Radiological%2C+and+Nuclear+%28CBRN%29+Disasters&rft.au=Bartenfeld%2C+Michael+T%3BPeacock%2C+Georgina%3BGriese%2C+Stephanie+E&rft.aulast=Bartenfeld&rft.aufirst=Michael&rft.date=2014-08-01&rft.volume=12&rft.issue=4&rft.spage=201&rft.isbn=&rft.btitle=&rft.title=Biosecurity+and+Bioterrorism&rft.issn=15387135&rft_id=info:doi/10.1089%2Fbsp.2014.0036 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-09-01 N1 - Last updated - 2015-09-03 N1 - SubjectsTermNotLitGenreText - Personnel; bioterrorism; Children; Public health DO - http://dx.doi.org/10.1089/bsp.2014.0036 ER - TY - JOUR T1 - Relationship Between Employment Characteristics and Obesity Among Employed U.S. Adults AN - 1680443814; 20587684 AB - Purpose. This study examined associations between employment characteristics and obesity among a sample representing civilian noninstitutionalized U.S. adults. Design. Quantitative, cross-sectional study. Setting. Workplace. Subjects. The 2010 National Health Interview Survey data for 15,121 employed adults (> or = 18 years). Measures. The outcome variable was weight status, and exposure variables were employment characteristics (number of employees, work hours, paid by the hour, paid sick leave, and health insurance offered). Analysis. Multivariate logistic regression was used to estimate adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for employment characteristics associated with obesity (body mass index [BMI] > or = 30 kg/m super(2)) after controlling for age, sex, race/ethnicity, education, family income, fruit/vegetable intake, physical activity, smoking, and occupations. Results. Nationwide, 28% of employed adults were obese. From multivariate logistic regression, the odds of being obese was significantly greater among adults who worked at a company with 100 to 499 employees (OR= 1.19, 95% CI= 1.02-1.39) vs. with 1 to 24 employees and those who worked >50 hours/week (OR = 1.32, 95% CI = 1.05-1.65) vs. <30 hours/week. Conclusion. Approximately 3 out of 10 employees were obese and 6 out of 10 were overweight or obese. A better understanding of why these employment characteristics are associated with obesity could help employers better develop and target interventions for obesity prevention and treatment in the worksites. JF - American Journal of Health Promotion AU - Park, Sohyun AU - Pan, Liping AU - Lankford, Tina AD - Division of Nutrition, Physical Activity and Obesity, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, spark3@cdc.gov Y1 - 2014/08// PY - 2014 DA - Aug 2014 SP - 389 EP - 396 PB - American Journal of Health Promotion, 1660 Cass Lake Road, Suite 104 Keego Harbor MI 48320 United States VL - 28 IS - 6 SN - 0890-1171, 0890-1171 KW - Physical Education Index KW - Employment KW - Obesity KW - Weight Status KW - Adults KW - Employees KW - Worksite KW - Workplace KW - Prevention Research KW - Body mass KW - Health KW - Interviews KW - Exercise KW - Insurance KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1680443814?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Health+Promotion&rft.atitle=Relationship+Between+Employment+Characteristics+and+Obesity+Among+Employed+U.S.+Adults&rft.au=Park%2C+Sohyun%3BPan%2C+Liping%3BLankford%2C+Tina&rft.aulast=Park&rft.aufirst=Sohyun&rft.date=2014-08-01&rft.volume=28&rft.issue=6&rft.spage=389&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Health+Promotion&rft.issn=08901171&rft_id=info:doi/10.4278%2Fajhp.130207-QUAN-64 LA - English DB - Physical Education Index N1 - Date revised - 2015-05-01 N1 - Last updated - 2015-06-12 N1 - SubjectsTermNotLitGenreText - Obesity; Body mass; Employees; Health; Exercise; Interviews; Adults; Employment; Insurance DO - http://dx.doi.org/10.4278/ajhp.130207-QUAN-64 ER - TY - JOUR T1 - Neoplastic-like transformation effect of singlewalled and multi-walled carbon nanotubes compared to asbestos on human lung small airway epithelial cells AN - 1639983017; 21120925 AB - Accumulating evidence indicates that carbon nanotubes (CNTs) are biopersistent and can cause lung damage. With similar fibrous morphology and mode of exposure to asbestos, a known human carcinogen, growing concern has arisen for elevated risk of CNT-induced lung carcinogenesis; however, relatively little is known about the long-term carcinogenic effect of CNT. Neoplastic transformation is a key early event leading to carcinogenesis. We studied the ability of single- and multi-walled CNTs to induce neoplastic transformation of human lung epithelial cells compared to asbestos. Long-term (6-month) exposure of the cells to occupationally relevant concentrations of CNT in culture caused a neoplastic-like transformation phenotype as demonstrated by increased cell proliferation, anchorage-independent growth, invasion and angiogenesis. Whole-genome expression signature and protein expression analyses showed that single- and multi-walled CNTs shared similar signaling signatures which were distinct from asbestos. These results provide novel toxicogenomic information and suggest distinct particle associated mechanisms of neoplasia promotion induced by CNTs and asbestos. JF - Nanotoxicology AU - Wang, Liying AU - Stueckle, Todd A AU - Mishra, Anurag AU - Derk, Raymond AU - Meighan, Terence AU - Castranova, Vincent AU - Rojanasakul, Yon AD - Liying Wang, HELD/PPRB, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown WV 26505, USA, lmw6@cdc.govandjux5@cdc.gov Y1 - 2014/08// PY - 2014 DA - Aug 2014 SP - 485 EP - 507 PB - Informa Healthcare, 52 Vanderbilt Ave. New York New York 10017 USA VL - 8 IS - 5 SN - 1743-5390, 1743-5390 KW - Toxicology Abstracts KW - lung KW - neoplastic transformation KW - invasion KW - genome expression KW - microarray KW - Transformation KW - Epithelial cells KW - Asbestos KW - Angiogenesis KW - Cell culture KW - Carcinogens KW - Neoplasia KW - Carbon KW - Lung KW - Carcinogenesis KW - nanotubes KW - Cell proliferation KW - Respiratory tract KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1639983017?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Nanotoxicology&rft.atitle=Neoplastic-like+transformation+effect+of+singlewalled+and+multi-walled+carbon+nanotubes+compared+to+asbestos+on+human+lung+small+airway+epithelial+cells&rft.au=Wang%2C+Liying%3BStueckle%2C+Todd+A%3BMishra%2C+Anurag%3BDerk%2C+Raymond%3BMeighan%2C+Terence%3BCastranova%2C+Vincent%3BRojanasakul%2C+Yon&rft.aulast=Wang&rft.aufirst=Liying&rft.date=2014-08-01&rft.volume=8&rft.issue=5&rft.spage=485&rft.isbn=&rft.btitle=&rft.title=Nanotoxicology&rft.issn=17435390&rft_id=info:doi/10.3109%2F17435390.2013.801089 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-12-01 N1 - Last updated - 2015-05-13 N1 - SubjectsTermNotLitGenreText - Transformation; Epithelial cells; Asbestos; Angiogenesis; Cell culture; Carcinogens; Neoplasia; Carbon; Lung; Carcinogenesis; nanotubes; Cell proliferation; Respiratory tract DO - http://dx.doi.org/10.3109/17435390.2013.801089 ER - TY - JOUR T1 - An Investigational Antiviral Drug, DAS181, Effectively Inhibits Replication of Zoonotic Influenza A Virus Subtype H7N9 and Protects Mice From Lethality AN - 1618148581; 20800451 AB - Human infections caused by avian influenza A virus type sub-type H7N9 have been associated with substantial morbidity and mortality. Emergence of virus variants carrying markers of decreased susceptibility to neuraminidase inhibitors was reported. Here we show that DAS181 (Fludase), an antiviral drug with sialidase activity, potently inhibited replication of wild-type influenza A(H7N9) and its oseltamivir-resistant R292K variants in mice. A once-daily administration initiated early after lethal infection hampered body weight loss and completely protected mice from lethality. We observed a time-dependent effect for 24-72-hour delayed DAS181 treatments on morbidity and mortality. The results warrant further investigation of DAS181 for influenza treatment. JF - Journal of Infectious Diseases AU - Marjuki, Henju AU - Mishin, Vasiliy P AU - Chesnokov, Anton P AU - De La Cruz, Juan A AU - Fry, Alicia M AU - Villanueva, Julie AU - Gubareva, Larisa V AD - Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, lgubareva@cdc.gov Y1 - 2014/08/01/ PY - 2014 DA - 2014 Aug 01 SP - 435 EP - 440 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 210 IS - 3 SN - 0022-1899, 0022-1899 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Virology & AIDS Abstracts KW - H7N9 KW - Fludase (DAS181) KW - oseltamivir KW - drug resistance KW - R292K KW - neuraminidase inhibitor KW - Body weight loss KW - Mortality KW - Fowl plague KW - Lethality KW - Antiviral agents KW - Replication KW - Influenza A virus KW - Exo- alpha -sialidase KW - Infection KW - Morbidity KW - A 01340:Antibiotics & Antimicrobials KW - V 22320:Replication UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1618148581?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=An+Investigational+Antiviral+Drug%2C+DAS181%2C+Effectively+Inhibits+Replication+of+Zoonotic+Influenza+A+Virus+Subtype+H7N9+and+Protects+Mice+From+Lethality&rft.au=Marjuki%2C+Henju%3BMishin%2C+Vasiliy+P%3BChesnokov%2C+Anton+P%3BDe+La+Cruz%2C+Juan+A%3BFry%2C+Alicia+M%3BVillanueva%2C+Julie%3BGubareva%2C+Larisa+V&rft.aulast=Marjuki&rft.aufirst=Henju&rft.date=2014-08-01&rft.volume=210&rft.issue=3&rft.spage=435&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjiu105 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-10-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Body weight loss; Fowl plague; Mortality; Lethality; Antiviral agents; Replication; Exo- alpha -sialidase; Infection; Morbidity; Influenza A virus DO - http://dx.doi.org/10.1093/infdis/jiu105 ER - TY - JOUR T1 - IgM, IgG, and IgA Antibody Responses to Influenza A(H1N1)pdm09 Hemagglutinin in Infected Persons during the First Wave of the 2009 Pandemic in the United States AN - 1560109175; 20602590 AB - The novel influenza A(H1N1)pdm09 virus caused an influenza pandemic in 2009. IgM, IgG, and IgA antibody responses to A(H1N1)pdm09 hemagglutinin (HA) following A(H1N1)pdm09 virus infection were analyzed to understand antibody isotype responses. Age-matched control sera collected from U.S. residents in 2007 and 2008 were used to establish baseline levels of cross-reactive antibodies. IgM responses often used as indicators of primary virus infection were mainly detected in young patient groups ( less than or equal to 5 years and 6 to 15 years old), not in older age groups, despite the genetic and antigenic differences between the HA of A(H1N1)pdm09 virus and pre-2009 seasonal H1N1 viruses. IgG and IgA responses to A(H1N1)pdm09 HA were detected in all age groups of infected persons. In persons 17 to 80 years old, paired acute- and convalescent-phase serum samples demonstrated greater than or equal to 4-fold increases in the IgG and IgA responses to A(H1N1)pdm09 HA in 80% and 67% of A(H1N1)pdm09 virus-infected persons, respectively. The IgG antibody response to A(H1N1)pdm09 HA was cross-reactive with HAs from H1, H3, H5, and H13 subtypes, suggesting that infections with subtypes other than A(H1N1)pdm09 might result in false positives by enzyme-linked immunosorbent assay (ELISA). Lower sensitivity compared to hemagglutination inhibition and microneutralization assays and the detection of cross-reactive antibodies against homologous and heterologous subtype are major drawbacks for the application of ELISA in influenza serologic studies. JF - Clinical and Vaccine Immunology AU - Li, Zhu-Nan AU - Lin, Seh-Ching AU - Carney, Paul J AU - Li, Ji AU - Liu, Feng AU - Lu, Xiuhua AU - Liu, Merry AU - Stevens, James AU - Levine, Min AU - Katz, Jacqueline M AD - Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, hix7@cdc.gov. Y1 - 2014/08// PY - 2014 DA - Aug 2014 SP - 1054 EP - 1060 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 21 IS - 8 SN - 1556-6811, 1556-6811 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts; Immunology Abstracts KW - Sensitivity KW - Enzyme-linked immunosorbent assay KW - Immunology KW - Hemagglutinins KW - Hemagglutination inhibition KW - Viruses KW - Antibody response KW - Infection KW - Influenza KW - USA KW - Immunoglobulin A KW - pandemics KW - Sulfur dioxide KW - Immunoglobulin G KW - Geriatrics KW - Age groups KW - Waves KW - Vaccines KW - Seasonal variations KW - Immunoassays KW - Immunoglobulin M KW - V 22350:Immunology KW - F 06905:Vaccines KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1560109175?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+and+Vaccine+Immunology&rft.atitle=IgM%2C+IgG%2C+and+IgA+Antibody+Responses+to+Influenza+A%28H1N1%29pdm09+Hemagglutinin+in+Infected+Persons+during+the+First+Wave+of+the+2009+Pandemic+in+the+United+States&rft.au=Li%2C+Zhu-Nan%3BLin%2C+Seh-Ching%3BCarney%2C+Paul+J%3BLi%2C+Ji%3BLiu%2C+Feng%3BLu%2C+Xiuhua%3BLiu%2C+Merry%3BStevens%2C+James%3BLevine%2C+Min%3BKatz%2C+Jacqueline+M&rft.aulast=Li&rft.aufirst=Zhu-Nan&rft.date=2014-08-01&rft.volume=21&rft.issue=8&rft.spage=1054&rft.isbn=&rft.btitle=&rft.title=Clinical+and+Vaccine+Immunology&rft.issn=15566811&rft_id=info:doi/10.1128%2FCVI.00129-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Number of references - 44 N1 - Last updated - 2014-12-11 N1 - SubjectsTermNotLitGenreText - Influenza; pandemics; Enzyme-linked immunosorbent assay; Immunoglobulin A; Hemagglutination inhibition; Hemagglutinins; Geriatrics; Immunoglobulin G; Waves; Antibody response; Infection; Immunoglobulin M; Sensitivity; Sulfur dioxide; Immunology; Viruses; Age groups; Vaccines; Immunoassays; Seasonal variations; USA DO - http://dx.doi.org/10.1128/CVI.00129-14 ER - TY - JOUR T1 - Multilocus Sequence Typing Confirms Wild Birds as the Source of a Campylobacter Outbreak Associated with the Consumption of Raw Peas AN - 1560109032; 20602635 AB - From August to September 2008, the Centers for Disease Control and Prevention (CDC) assisted the Alaska Division of Public Health with an outbreak investigation of campylobacteriosis occurring among the residents of Southcentral Alaska. During the investigation, pulsed-field gel electrophoresis (PFGE) of Campylobacter jejuni isolates from human, raw pea, and wild bird fecal samples confirmed the epidemiologic link between illness and the consumption of raw peas contaminated by sandhill cranes for 15 of 43 epidemiologically linked human isolates. However, an association between the remaining epidemiologically linked human infections and the pea and wild bird isolates was not established. To better understand the molecular epidemiology of the outbreak, C. jejuni isolates (n = 130; 59 from humans, 40 from peas, and 31 from wild birds) were further characterized by multilocus sequence typing (MLST). Here we present the molecular evidence to demonstrate the association of many more human C. jejuni infections associated with the outbreak with raw peas and wild bird feces. Among all sequence types (STs) identified, 26 of 39 (67%) were novel and exclusive to the outbreak. Five clusters of overlapping STs (n = 32 isolates; 17 from humans, 2 from peas, and 13 from wild birds) were identified. In particular, cluster E (n = 7 isolates; ST-5049) consisted of isolates from humans, peas, and wild birds. Novel STs clustered closely with isolates typically associated with wild birds and the environment but distinct from lineages commonly seen in human infections. Novel STs and alleles recovered from human outbreak isolates allowed additional infections caused by these rare genotypes to be attributed to the contaminated raw peas. JF - Applied and Environmental Microbiology AU - Kwan, Patrick SL AU - Xavier, Catherine AU - Santovenia, Monica AU - Pruckler, Janet AU - Stroika, Steven AU - Joyce, Kevin AU - Gardner, Tracie AU - Fields, Patricia I AU - McLaughlin, Joe AU - Tauxe, Robert V AD - Enteric Diseases Laboratory Branch, Division of Foodborne, Waterborne and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, pkwan@cdc.gov. Y1 - 2014/08// PY - 2014 DA - Aug 2014 SP - 4540 EP - 4546 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA, [URL:http://www.asm.org/] VL - 80 IS - 15 SN - 0099-2240, 0099-2240 KW - Health & Safety Science Abstracts; Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - USA, Alaska KW - Fecal coliforms KW - Electrophoresis KW - Disease control KW - Campylobacteriosis KW - Genotypes KW - Infection KW - multilocus sequence typing KW - Public health KW - Aves KW - Prevention KW - Epidemiology KW - Campylobacter jejuni KW - Pulsed-field gel electrophoresis KW - Outbreaks KW - Feces KW - A 01380:Plant Protection, Fungicides & Seed Treatments KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1560109032?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Multilocus+Sequence+Typing+Confirms+Wild+Birds+as+the+Source+of+a+Campylobacter+Outbreak+Associated+with+the+Consumption+of+Raw+Peas&rft.au=Kwan%2C+Patrick+SL%3BXavier%2C+Catherine%3BSantovenia%2C+Monica%3BPruckler%2C+Janet%3BStroika%2C+Steven%3BJoyce%2C+Kevin%3BGardner%2C+Tracie%3BFields%2C+Patricia+I%3BMcLaughlin%2C+Joe%3BTauxe%2C+Robert+V&rft.aulast=Kwan&rft.aufirst=Patrick&rft.date=2014-08-01&rft.volume=80&rft.issue=15&rft.spage=4540&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/10.1128%2FAEM.00537-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Number of references - 43 N1 - Last updated - 2014-10-30 N1 - SubjectsTermNotLitGenreText - Epidemiology; Pulsed-field gel electrophoresis; Disease control; Genotypes; Campylobacteriosis; Feces; Infection; Public health; multilocus sequence typing; Aves; Prevention; Fecal coliforms; Electrophoresis; Outbreaks; Campylobacter jejuni; USA, Alaska DO - http://dx.doi.org/10.1128/AEM.00537-14 ER - TY - JOUR T1 - The Predictive Influence of Family and Neighborhood Assets on Fighting and Weapon Carrying from Mid- to Late Adolescence AN - 1554951850; 20487002 AB - Using a developmental, social-ecological approach to understand the etiology of health-risk behavior and inform primary prevention efforts, we assess the predictive effects of family and neighborhood social processes on youth physical fighting and weapon carrying. Specifically, we focus on relationships among youth and their parents, family communication, parental monitoring, as well as sense of community and neighborhood informal social control, support, concerns, and disorder. This study advances knowledge through its investigation of family and neighborhood structural factors and social processes together, employment of longitudinal models that estimate effects over adolescent development, and use of self-report and observational measures. Data from 1,093 youth/parent pairs were analyzed from the Youth Assets Study using a Generalized Estimating Equation approach; family and neighborhood assets and risks were analyzed as time varying and lagged. Similar family assets affected physical fighting and weapon carrying, whereas different neighborhood social processes influenced the two forms of youth violence. Study findings have implications for the primary prevention of youth violence, including the use of family-based approaches that build relationships and parental monitoring skills and community-level change approaches that promote informal social control and reduce neighborhood concerns about safety. JF - Prevention Science AU - Haegerich, Tamara M AU - Oman, Roy F AU - Vesely, Sara K AU - Aspy, Cheryl B AU - Tolma, Eleni L AD - Division of Unintentional Injury Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, 4770 Buford Highway MS F-62, Atlanta, GA, 30341, USA, eqd4@cdc.gov Y1 - 2014/08// PY - 2014 DA - Aug 2014 SP - 473 EP - 484 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 15 IS - 4 SN - 1389-4986, 1389-4986 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Risk assessment KW - Weapons KW - Prevention KW - Etiology KW - Communications KW - Risk factors KW - Safety KW - Employment KW - Violence KW - Adolescents KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1554951850?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Prevention+Science&rft.atitle=The+Predictive+Influence+of+Family+and+Neighborhood+Assets+on+Fighting+and+Weapon+Carrying+from+Mid-+to+Late+Adolescence&rft.au=Haegerich%2C+Tamara+M%3BOman%2C+Roy+F%3BVesely%2C+Sara+K%3BAspy%2C+Cheryl+B%3BTolma%2C+Eleni+L&rft.aulast=Haegerich&rft.aufirst=Tamara&rft.date=2014-08-01&rft.volume=15&rft.issue=4&rft.spage=473&rft.isbn=&rft.btitle=&rft.title=Prevention+Science&rft.issn=13894986&rft_id=info:doi/10.1007%2Fs11121-013-0400-z LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-08-01 N1 - Number of references - 59 N1 - Last updated - 2014-09-05 N1 - SubjectsTermNotLitGenreText - Risk assessment; Etiology; Prevention; Weapons; Communications; Risk factors; Safety; Employment; Violence; Adolescents DO - http://dx.doi.org/10.1007/s11121-013-0400-z ER - TY - JOUR T1 - Cost of services provided by the National Breast and Cervical Cancer Early Detection Program AN - 1554946400; 20503499 AB - BACKGROUND The National Breast and Cervical Cancer Early Detection Program (NBCCEDP) is the largest cancer screening program for low-income women in the United States. This study updates previous estimates of the costs of delivering preventive cancer screening services in the NBCCEDP. METHODS: We developed a standardized web-based cost-assessment tool to collect annual activity-based cost data on screening for breast and cervical cancer in the NBCCEDP. Data were collected from 63 of the 66 programs that received funding from the Centers for Disease Control and Prevention during the 2006/2007 fiscal year. We used these data to calculate costs of delivering preventive public health services in the program. RESULTS: We estimated the total cost of all NBCCEDP services to be $296 (standard deviation [SD], $123) per woman served (including the estimated value of in-kind donations, which constituted approximately 15% of this total estimated cost). The estimated cost of screening and diagnostic services was $145 (SD, $38) per women served, which represented 57.7% of the total cost excluding the value of in-kind donations. Including the value of in-kind donations, the weighted mean cost of screening a woman for breast cancer was $110 with an office visit and $88 without, the weighted mean cost of a diagnostic procedure was $401, and the weighted mean cost per breast cancer detected was $35,480. For cervical cancer, the corresponding cost estimates were $61, $21, $415, and $18,995, respectively. CONCLUSIONS: These NBCCEDP cost estimates may help policy makers in planning and implementing future costs for various potential changes to the program. Cancer 2014; 120(16 suppl):2604-11. copyright 2014 American Cancer Society. This study updates and extends previously published estimates of the costs of providing cancer screening and diagnostic services through the National Breast and Cervical Cancer Early Detection Program. Policy makers may find these cost estimates useful in estimating the costs of potential future changes to the program. JF - Cancer AU - Ekwueme, Donatus U AU - Subramanian, Sujha AU - Trogdon, Justin G AU - Miller, Jacqueline W AU - Royalty, Janet E AU - Li, Chunyu AU - Guy, Gery P AU - Crouse, Wesley AU - Thompson, Hope AU - Gardner, James G AD - Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia. Y1 - 2014/08// PY - 2014 DA - Aug 2014 SP - 2604 EP - 2611 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 120 IS - S16 SN - 0008-543X, 0008-543X KW - Health & Safety Science Abstracts KW - USA KW - Prevention KW - Disease control KW - Socioeconomics KW - Standards KW - Public health KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1554946400?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cancer&rft.atitle=Cost+of+services+provided+by+the+National+Breast+and+Cervical+Cancer+Early+Detection+Program&rft.au=Ekwueme%2C+Donatus+U%3BSubramanian%2C+Sujha%3BTrogdon%2C+Justin+G%3BMiller%2C+Jacqueline+W%3BRoyalty%2C+Janet+E%3BLi%2C+Chunyu%3BGuy%2C+Gery+P%3BCrouse%2C+Wesley%3BThompson%2C+Hope%3BGardner%2C+James+G&rft.aulast=Ekwueme&rft.aufirst=Donatus&rft.date=2014-08-01&rft.volume=120&rft.issue=S16&rft.spage=2604&rft.isbn=&rft.btitle=&rft.title=Cancer&rft.issn=0008543X&rft_id=info:doi/10.1002%2Fcncr.28816 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-08-01 N1 - Last updated - 2014-09-05 N1 - SubjectsTermNotLitGenreText - Prevention; Disease control; Socioeconomics; Standards; Public health; USA DO - http://dx.doi.org/10.1002/cncr.28816 ER - TY - JOUR T1 - Public health national approach to reducing breast and cervical cancer disparities AN - 1554945759; 20503493 AB - Breast and cervical cancer have had disparate impact on the lives of women. The burden of breast and cervical cancer is more prominent among some racial and ethnic minority women. Providing comprehensive care to all medically underserved women is a critical element in continuing the battle to reduce cancer burden and eliminate disparities. The National Breast and Cervical Cancer Early Detection Program is the only nationally organized cancer screening program for underserved women in the United States. Its public health goal is to ensure access to high-quality screening, follow-up, and treatment services for diverse and vulnerable populations that, in turn, may reduce disparities. Cancer 2014; 120(16 suppl):2537-9. Published 2014. This article is a U.S. Government work and is in the public domain in the USA. The National Breast and Cervical Cancer Early Detection Program is the only nationally organized cancer screening program for underserved women in the United States. Its public health goal is to ensure access to high-quality screening, follow-up, and treatment services for diverse and vulnerable populations that, in turn, may reduce disparities. JF - Cancer AU - Miller, Jacqueline W AU - Plescia, Marcus AU - Ekwueme, Donatus U AD - Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia. Y1 - 2014/08// PY - 2014 DA - Aug 2014 SP - 2537 EP - 2539 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 120 IS - S16 SN - 0008-543X, 0008-543X KW - Health & Safety Science Abstracts KW - USA KW - Vulnerability KW - Ethnic groups KW - Public health KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1554945759?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cancer&rft.atitle=Public+health+national+approach+to+reducing+breast+and+cervical+cancer+disparities&rft.au=Miller%2C+Jacqueline+W%3BPlescia%2C+Marcus%3BEkwueme%2C+Donatus+U&rft.aulast=Miller&rft.aufirst=Jacqueline&rft.date=2014-08-01&rft.volume=120&rft.issue=S16&rft.spage=2537&rft.isbn=&rft.btitle=&rft.title=Cancer&rft.issn=0008543X&rft_id=info:doi/10.1002%2Fcncr.28818 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-08-01 N1 - Last updated - 2014-09-05 N1 - SubjectsTermNotLitGenreText - Vulnerability; Ethnic groups; Public health; USA DO - http://dx.doi.org/10.1002/cncr.28818 ER - TY - JOUR T1 - An efficient and rapid thin-layer chromatography method for the identification of 32 dye substances in hair dye products AN - 1554943250; 20494171 AB - The use of dye substances in hair dye products has led to controversial public and scientific discussions about their impact on human health. This study aimed to explore a rapid method for identification of dye substances in hair dye products. Thin layer chromatography (TLC) method was conducted in this study. We developed basic data of 32 dye substances by 4 developing solvents and 2 indicator sprays. The dye substances were identified by comparing the Rf values and colors between samples and reference substances. Thirty samples were identified by the established method. 22 hair dye substances were detected in 16 formula known samples, 15 hair dye substances were detected in 14 formula unknown samples. Four laboratories participated in the validation and the results showed good interlaboratory reproducibility. The developed TLC method is simple, rapid, reliable and can be finely used for identification of dye substances in hair dye products. An efficient and rapid thin-layer chromatography method has been developed for the identification of 32 dye substances in hair dye products.Original Abstract: Les substances de teinture sont certainement dangereux pour les humains. Elles sont parmi les ingredients cosmetiques les plus largement discutees et reglementees. Dans cette etude, une methode de chromatographie en couche mince (CCM) est developpee pour l'identification de 32 substances colorantes dans des produits de teinture pour cheveux. Cette methode CCM implique 4 solvants de developpement et deux sprays indicateurs. Les 32 substances de coloration sont identifiees en comparant les valeurs de Rf et des couleurs entre les echantillons et les substances de reference. Trente echantillons ont ete testes par la methode etablie. 22 substances de teintures capillaires ont ete detectees dans 16 echantillons de formules connues, 15 substances de teintures capillaires ont ete detectees dans 14 echantillons de formules inconnues. Quatre laboratoires ont participe a la validation et les resultats ont montre une bonne reproductibilite inter-laboratoire. La methode CCM developpe est simple, rapide, fiable et peut etre utilisee pour l'identification de substances colorantes dans les produits de teintures capillaires. JF - International Journal of Cosmetic Science AU - Zhu, HJ AU - Yang, Y W AU - Zhu, Y AD - Institute for Environmental Health and Related Product Safety. Chinese Center for Disease Control and Prevention Y1 - 2014/08// PY - 2014 DA - Aug 2014 SP - 369 EP - 378 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 36 IS - 4 SN - 0142-5463, 0142-5463 KW - Health & Safety Science Abstracts KW - Chromatography KW - Sprays KW - Solvents KW - Cosmetics KW - Hair KW - H 6000:Natural Disasters/Civil Defense/Emergency Management UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1554943250?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Cosmetic+Science&rft.atitle=An+efficient+and+rapid+thin-layer+chromatography+method+for+the+identification+of+32+dye+substances+in+hair+dye+products&rft.au=Zhu%2C+HJ%3BYang%2C+Y+W%3BZhu%2C+Y&rft.aulast=Zhu&rft.aufirst=HJ&rft.date=2014-08-01&rft.volume=36&rft.issue=4&rft.spage=369&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Cosmetic+Science&rft.issn=01425463&rft_id=info:doi/10.1111%2Fics.12135 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-08-01 N1 - Last updated - 2014-09-05 N1 - SubjectsTermNotLitGenreText - Chromatography; Sprays; Solvents; Cosmetics; Hair DO - http://dx.doi.org/10.1111/ics.12135 ER - TY - JOUR T1 - Perfluorooctanoate exposure and major birth defects. AN - 1551025210; 24803403 AB - Perfluorooctanoate (PFOA) is detectable in umbilical cord blood and amniotic fluid. Some toxicological findings suggest that perfluoroalkyl substances may be teratogenic. Using data from the C8 Health Project, a 2005-2006 survey in a Mid-Ohio Valley community exposed to PFOA through contaminated drinking water, we examined the association between estimated prenatal PFOA concentration and maternally reported birth defects (n=325) among 10,262 live singleton or multiple births from 1990 to 2006. Logistic regression models accounted for siblings using generalized estimating equations. There was generally no association between estimated PFOA concentration and birth defects, with the possible exception of brain defects, where the odds ratio adjusted for year of conception was 2.6 (95% confidence interval 1.3-5.1) for an increase in estimated PFOA exposure from the 25th to 75th percentile. This estimate, however, was based on 13 cases and may represent a chance finding. Further investigation of this potential association may be warranted. Copyright © 2014 Elsevier Inc. All rights reserved. JF - Reproductive toxicology (Elmsford, N.Y.) AU - Stein, Cheryl R AU - Savitz, David A AU - Elston, Beth AU - Thorpe, Phoebe G AU - Gilboa, Suzanne M AD - Department of Preventive Medicine, Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1057, New York, NY 10029-6574, United States. Electronic address: cheryl.stein@mssm.edu. ; Department of Epidemiology, Brown University School of Public Health, Providence, RI, United States. Electronic address: david_savitz@brown.edu. ; Department of Epidemiology, Brown University School of Public Health, Providence, RI, United States. Electronic address: beth_elston@brown.edu. ; National Center on Birth Defects and Developmental Disabilities, US Centers for Disease Control and Prevention, Atlanta, GA, United States. Electronic address: pht1@cdc.gov. ; National Center on Birth Defects and Developmental Disabilities, US Centers for Disease Control and Prevention, Atlanta, GA, United States. Electronic address: suz0@cdc.gov. Y1 - 2014/08// PY - 2014 DA - August 2014 SP - 15 EP - 20 VL - 47 KW - Caprylates KW - 0 KW - Fluorocarbons KW - Water Pollutants, Chemical KW - perfluorooctanoic acid KW - 947VD76D3L KW - Index Medicus KW - Congenital abnormalities KW - Epidemiology KW - Perfluorooctanoic acid KW - Young Adult KW - Odds Ratio KW - Humans KW - Adult KW - Ohio -- epidemiology KW - Infant, Newborn KW - Middle Aged KW - Adolescent KW - Female KW - Caprylates -- blood KW - Brain -- abnormalities KW - Environmental Exposure -- analysis KW - Fluorocarbons -- blood KW - Congenital Abnormalities -- epidemiology KW - Water Pollutants, Chemical -- blood UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1551025210?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Reproductive+toxicology+%28Elmsford%2C+N.Y.%29&rft.atitle=Perfluorooctanoate+exposure+and+major+birth+defects.&rft.au=Stein%2C+Cheryl+R%3BSavitz%2C+David+A%3BElston%2C+Beth%3BThorpe%2C+Phoebe+G%3BGilboa%2C+Suzanne+M&rft.aulast=Stein&rft.aufirst=Cheryl&rft.date=2014-08-01&rft.volume=47&rft.issue=&rft.spage=15&rft.isbn=&rft.btitle=&rft.title=Reproductive+toxicology+%28Elmsford%2C+N.Y.%29&rft.issn=1873-1708&rft_id=info:doi/10.1016%2Fj.reprotox.2014.04.006 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2015-04-07 N1 - Date created - 2014-08-01 N1 - Date revised - 2017-01-14 N1 - SuppNotes - Cited By: Int J Toxicol. 2001 Mar-Apr;20(2):101-9 [11354466] Toxicol Sci. 2007 Oct;99(2):366-94 [17519394] Toxicol Appl Pharmacol. 2004 Jul 15;198(2):231-41 [15236955] Environ Health Perspect. 2004 Aug;112(11):1204-7 [15289168] Environ Sci Technol. 2004 Jul 1;38(13):3698-704 [15296323] Toxicol Sci. 2006 Apr;90(2):510-8 [16415327] Environ Sci Technol. 2006 May 1;40(9):2924-9 [16719092] Int Arch Occup Environ Health. 2007 Jul;80(7):643-8 [17219182] Environ Health Perspect. 2007 Sep;115(9):1298-305 [17805419] Environ Sci Technol. 2008 Apr 15;42(8):3096-101 [18497172] Int J Hyg Environ Health. 2008 Jul;211(3-4):440-6 [17870667] Environ Res. 2008 Sep;108(1):56-62 [18649879] Environ Sci Technol. 2008 Nov 15;42(22):8597-602 [19068854] Toxicology. 2009 Feb 4;256(1-2):42-7 [19041924] Reprod Toxicol. 2009 Jun;27(3-4):212-30 [19429401] Am J Epidemiol. 2009 Oct 1;170(7):837-46 [19692329] Environ Health Perspect. 2009 Dec;117(12):1873-82 [20049206] Environ Health Perspect. 2010 Feb;118(2):222-8 [20123620] Reprod Toxicol. 2010 Apr;29(2):147-55 [19897029] Birth Defects Res A Clin Mol Teratol. 2010 Dec;88(12):1008-16 [20878909] Environ Sci Technol. 2011 Oct 1;45(19):8037-45 [21469664] Environ Sci Technol. 2011 Oct 1;45(19):7974-84 [21630688] Environ Health Perspect. 2011 Dec;119(12):1760-5 [21813367] Toxicology. 2012 Mar 11;293(1-3):97-106 [22273728] Epidemiology. 2012 May;23(3):386-92 [22370857] Environ Health Perspect. 2012 Jun;120(6):897-903 [22398305] Reprod Toxicol. 2012 Nov;34(3):312-6 [22613200] Environ Sci Technol. 2011 Feb 15;45(4):1435-42 [21226527] Toxicol In Vitro. 2013 Aug;27(5):1503-12 [23562911] Toxicol Sci. 2003 Aug;74(2):369-81 [12773773] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1016/j.reprotox.2014.04.006 ER - TY - JOUR T1 - Diversity of HIV/AIDS epidemic in China: a result from hierarchical clustering analysis and spatial autocorrelation analysis AN - 1765970091; PQ0002559467 AB - Objective: To find out the diversity of HIV/AIDS epidemic among different areas in China according to their varied epidemic characteristics. Design and methods: Seventeen provincial variables, generated from original HIV/ AIDS epidemic data and socioeconomic indicators to indicate HIV/AIDS epidemic characteristics, were introduced to hierarchical clustering analysis to form subepidemic areas. Then spatial autocorrelation analysis was applied to show the clustering distribution of cases from different most-at-risk populations. Results: Three HIV/AIDS subepidemic areas (A, B, C) were formed, each of which was further divided into two clusters, showing the diversity of HIV/AIDS epidemic in China. A1 was the earliest and severest HIV/AIDS epidemic area and occupied 37% hotspot counties. The epidemic in A1 was driven by IDU in its early period and heterosexual transmission later. Henan, the only province in A2, characterized by its HIV/AIDS epidemic among former plasma donors during the early 1990s, presented strong spatial clustering of blood/plasma transmission occupying 80% blood/plasma hotspots. The epidemic within B3, located in southwest China, was driven by IDU and heterosexual populations, and recently by MSM. The epidemic within B4, covering all four municipalities, had been largely spread among MSM since 2005. B3 and B4 occupied 76% MSM hotspots. For C5 and C6, only sporadic HIV/AIDS infections occurred in the last years among former plasma donors and heterosexual populations, whereas the prevalence among MSM had been increasing. Conclusion: China's different HIV/AIDS subepidemic areas had obvious diversity of affected populations, which should be considered when determining prevention policies. JF - AIDS AU - Qian, Shasha AU - Guo, Wei AU - Xing, Jiannan AU - Qin, Qianqian AU - Ding, Zhengwei AU - Chen, Fangfang AU - Peng, Zhihang AU - Wang, Lu AD - National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, wanglu64@163.com Y1 - 2014/07/31/ PY - 2014 DA - 2014 Jul 31 SP - 1805 EP - 1813 PB - Lippincott Williams & Wilkins, Inc, 530 Walnut Street Philadelphia PA 19106-3621 United States VL - 28 IS - 12 SN - 0269-9370, 0269-9370 KW - Health & Safety Science Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - clustering analysis KW - HIV/AIDS KW - socioeconomic factors KW - spatial analysis KW - Acquired immune deficiency syndrome KW - Epidemics KW - Data processing KW - Spatial distribution KW - Hot spots KW - Socioeconomics KW - Infection KW - Disease transmission KW - Blood KW - Socio-economic aspects KW - Prevention KW - Human immunodeficiency virus KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1765970091?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS&rft.atitle=Diversity+of+HIV%2FAIDS+epidemic+in+China%3A+a+result+from+hierarchical+clustering+analysis+and+spatial+autocorrelation+analysis&rft.au=Qian%2C+Shasha%3BGuo%2C+Wei%3BXing%2C+Jiannan%3BQin%2C+Qianqian%3BDing%2C+Zhengwei%3BChen%2C+Fangfang%3BPeng%2C+Zhihang%3BWang%2C+Lu&rft.aulast=Qian&rft.aufirst=Shasha&rft.date=2014-07-31&rft.volume=28&rft.issue=12&rft.spage=1805&rft.isbn=&rft.btitle=&rft.title=AIDS&rft.issn=02699370&rft_id=info:doi/10.1097%2FQAD.0000000000000323 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Socio-economic aspects; Blood; Acquired immune deficiency syndrome; Data processing; Epidemics; Hot spots; Infection; Disease transmission; Prevention; Spatial distribution; Human immunodeficiency virus; Socioeconomics DO - http://dx.doi.org/10.1097/QAD.0000000000000323 ER - TY - JOUR T1 - Pre-travel preparation practices among business travellers to tropical and subtropical destinations: Results from the Athens International Airport Survey AN - 1727695647; 20505185 AB - Background The number of business travellers from Greece to tropical and subtropical areas has recently increased. The study aimed to assess travel health preparation practices of business travellers departing to Africa, the Middle East and Asia. Method A questionnaire-based survey was conducted at Athens International Airport, from 1st of November 2011 to 30th of April 2013. Results A total of 684 business travellers participated in the study; the majority were men (86.1%), of Greek nationality (95.3%), with tertiary education (90.8%) and employed (98%). Their mean age was 40 years; 62% and 26% of them were 35-49 and 19-34 years of age respectively. 84.8% were travelling alone. Most frequent destinations were the Middle East (46.8%) and sub-Saharan Africa (16%). For 23.5% of the travellers it was their first trip to a tropical or subtropical country. Only 58.8% pursued pre-travel health consultation; vaccination and malaria chemoprophylaxis were administered to 24.7% and 25.7% of the travellers, respectively. Hepatitis A and typhoid vaccination rates were lower than expected (70% and 35%, respectively). Nearly half of the travellers who visited malaria endemic areas did not receive any chemoprophylaxis. Having elementary education level, travelling to the Middle East or North Africa, travelling for less than 1 month duration, and staying in a house or a hotel were associated with a higher probability of not pursuing health consultation. Conclusions Significant gaps were found in pre-travel health practices of business travellers departing to Africa, the Middle East and Asia. Strategies should be developed in order to improve awareness of business travellers. JF - Travel Medicine and Infectious Disease AU - Pavli, Androula AU - Silvestros, Chrysovalantis AU - Patrinos, Stavros AU - Lymperi, Ioanna AU - Maltezou, Helena C AD - Travel Medicine Office, Hellenic Center for Disease Control and Prevention, Athens, Greece Y1 - 2014/07// PY - 2014 DA - July 2014 SP - 364 EP - 369 PB - Elsevier VL - 12 IS - 4 SN - 1477-8939, 1477-8939 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources KW - Health advice KW - Practices KW - Business KW - Airport KW - Travellers KW - Human diseases KW - Hepatitis A virus KW - Malaria KW - Companies KW - Vaccination KW - Public health KW - MED, Greece KW - Education KW - Endemic species KW - Infectious diseases KW - Tropical environment KW - Africa KW - Asia KW - Middle East KW - Q1 08604:Stock assessment and management KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727695647?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Travel+Medicine+and+Infectious+Disease&rft.atitle=Pre-travel+preparation+practices+among+business+travellers+to+tropical+and+subtropical+destinations%3A+Results+from+the+Athens+International+Airport+Survey&rft.au=Pavli%2C+Androula%3BSilvestros%2C+Chrysovalantis%3BPatrinos%2C+Stavros%3BLymperi%2C+Ioanna%3BMaltezou%2C+Helena+C&rft.aulast=Pavli&rft.aufirst=Androula&rft.date=2014-07-01&rft.volume=12&rft.issue=4&rft.spage=364&rft.isbn=&rft.btitle=&rft.title=Travel+Medicine+and+Infectious+Disease&rft.issn=14778939&rft_id=info:doi/10.1016%2Fj.tmaid.2013.12.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Endemic species; Human diseases; Education; Infectious diseases; Tropical environment; Malaria; Companies; Vaccination; Public health; Hepatitis A virus; MED, Greece; Africa; Asia; Middle East DO - http://dx.doi.org/10.1016/j.tmaid.2013.12.004 ER - TY - JOUR T1 - Prevention of chronic disease in the 21st century: elimination of the leading preventable causes of premature death and disability in the USA AN - 1551645356; 20237564 AB - With non-communicable conditions accounting for nearly two-thirds of deaths worldwide, the emergence of chronic diseases as the predominant challenge to global health is undisputed. In the USA, chronic diseases are the main causes of poor health, disability, and death, and account for most of health-care expenditures. The chronic disease burden in the USA largely results from a short list of risk factors-including tobacco use, poor diet and physical inactivity (both strongly associated with obesity), excessive alcohol consumption, uncontrolled high blood pressure, and hyperlipidaemia-that can be effectively addressed for individuals and populations. Increases in the burden of chronic diseases are attributable to incidence and prevalence of leading chronic conditions and risk factors (which occur individually and in combination), and population demographics, including ageing and health disparities. To effectively and equitably address the chronic disease burden, public health and health-care systems need to deploy integrated approaches that bundle strategies and interventions, address many risk factors and conditions simultaneously, create population-wide changes, help the population subgroups most affected, and rely on implementation by many sectors, including public-private partnerships and involvement from all stakeholders. To help to meet the chronic disease burden, the US Centers for Disease Control and Prevention (CDC) uses four cross-cutting strategies: (1) epidemiology and surveillance to monitor trends and inform programmes; (2) environmental approaches that promote health and support healthy behaviours; (3) health system interventions to improve the effective use of clinical and other preventive services; and (4) community resources linked to clinical services that sustain improved management of chronic conditions. Establishment of community conditions to support healthy behaviours and promote effective management of chronic conditions will deliver healthier students to schools, healthier workers to employers and businesses, and a healthier population to the health-care system. Collectively, these four strategies will prevent the occurrence of chronic diseases, foster early detection and slow disease progression in people with chronic conditions, reduce complications, support an improved quality of life, and reduce demand on the health-care system. Of crucial importance, with strengthened collaboration between the public health and health-care sectors, the health-care system better uses prevention and early detection services, and population health is improved and sustained by solidifying collaborations between communities and health-care providers. This collaborative approach will improve health equity by building communities that promote health rather than disease, have more accessible and direct care, and focus the health-care system on improving population health. JF - Lancet AU - Bauer, Ursula E AU - Briss, Peter A AU - Goodman, Richard A AU - Bowman, Barbara A AD - National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA Y1 - 2014/07// PY - 2014 DA - Jul 2014 SP - 45 EP - 52 PB - The Lancet Ltd., 655 Ave. of the Americas New York NY 10011 United States VL - 384 IS - 9937 SN - 0140-6736, 0140-6736 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Diets KW - Stakeholders KW - Alcohol KW - Mortality KW - Complications KW - Physical activity KW - Disease control KW - Intervention KW - Public health KW - Demography KW - USA KW - Prevention KW - Schools KW - Disabilities KW - Risk factors KW - R2 23060:Medical and environmental health KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1551645356?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Lancet&rft.atitle=Prevention+of+chronic+disease+in+the+21st+century%3A+elimination+of+the+leading+preventable+causes+of+premature+death+and+disability+in+the+USA&rft.au=Bauer%2C+Ursula+E%3BBriss%2C+Peter+A%3BGoodman%2C+Richard+A%3BBowman%2C+Barbara+A&rft.aulast=Bauer&rft.aufirst=Ursula&rft.date=2014-07-01&rft.volume=384&rft.issue=9937&rft.spage=45&rft.isbn=&rft.btitle=&rft.title=Lancet&rft.issn=01406736&rft_id=info:doi/10.1016%2FS0140-6736%2814%2960648-6 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-08-01 N1 - Last updated - 2014-09-05 N1 - SubjectsTermNotLitGenreText - Diets; Mortality; Alcohol; Stakeholders; Complications; Physical activity; Disease control; Intervention; Public health; Demography; Prevention; Schools; Risk factors; Disabilities; USA DO - http://dx.doi.org/10.1016/S0140-6736(14)60648-6 ER - TY - JOUR T1 - Challenges of infectious diseases in the USA AN - 1551613241; 20237576 AB - In the USA, infectious diseases continue to exact a substantial toll on health and health-care resources. Endemic diseases such as chronic hepatitis, HIV, and other sexually transmitted infections affect millions of individuals and widen health disparities. Additional concerns include health-care-associated and foodborne infections-both of which have been targets of broad prevention efforts, with success in some areas, yet major challenges remain. Although substantial progress in reduction of the burden of vaccine-preventable diseases has been made, continued cases and outbreaks of these diseases persist, driven by various contributing factors. Worldwide, emerging and reemerging infections continue to challenge prevention and control strategies while the growing problem of antimicrobial resistance needs urgent action. An important priority for control of infectious disease is to ensure that scientific and technological advances in molecular diagnostics and bioinformatics are well integrated into public health. Broad and diverse partnerships across governments, health care, academia, and industry, and with the public, are essential to effectively reduce the burden of infectious diseases. JF - Lancet AU - Khabbaz, Rima F AU - Moseley, Robin R AU - Steiner, Riley J AU - Levitt, Alexandra M AU - Bell, Beth P AD - Office of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA Y1 - 2014/07// PY - 2014 DA - Jul 2014 SP - 53 EP - 63 PB - The Lancet Ltd., 655 Ave. of the Americas New York NY 10011 United States VL - 384 IS - 9937 SN - 0140-6736, 0140-6736 KW - Health & Safety Science Abstracts KW - Infection KW - Food-borne diseases KW - Antimicrobial agents KW - Public health KW - Hepatitis KW - USA KW - Prevention KW - Health care KW - Infectious diseases KW - Human immunodeficiency virus KW - Priorities KW - Outbreaks KW - Vaccines KW - Bioinformatics KW - Sexually transmitted diseases KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1551613241?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Lancet&rft.atitle=Challenges+of+infectious+diseases+in+the+USA&rft.au=Khabbaz%2C+Rima+F%3BMoseley%2C+Robin+R%3BSteiner%2C+Riley+J%3BLevitt%2C+Alexandra+M%3BBell%2C+Beth+P&rft.aulast=Khabbaz&rft.aufirst=Rima&rft.date=2014-07-01&rft.volume=384&rft.issue=9937&rft.spage=53&rft.isbn=&rft.btitle=&rft.title=Lancet&rft.issn=01406736&rft_id=info:doi/10.1016%2FS0140-6736%2814%2960890-4 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-08-01 N1 - Last updated - 2014-09-05 N1 - SubjectsTermNotLitGenreText - Infection; Food-borne diseases; Public health; Antimicrobial agents; Hepatitis; Prevention; Infectious diseases; Health care; Human immunodeficiency virus; Priorities; Bioinformatics; Vaccines; Outbreaks; Sexually transmitted diseases; USA DO - http://dx.doi.org/10.1016/S0140-6736(14)60890-4 ER - TY - JOUR T1 - Clinical, laboratory, diagnostic, and histopathologic features of diethylene glycol poisoning--Panama, 2006. AN - 1539466803; 24439712 AB - Diethylene glycol is a toxic industrial solvent responsible for more than 13 mass poisonings since 1937. Little is known about the clinical spectrum, progression, and neurotoxic potential of diethylene glycol-associated disease because of its high mortality and the absence of detailed information in published mass poisoning reports. This incident includes the largest proportion of cases with neurotoxic signs and symptoms. We characterize the features of a diethylene glycol mass poisoning resulting from a contaminated cough syrup distributed in Panama during 2006. This was a retrospective chart review and descriptive analysis in a tertiary level, urban health care facility. A case was a person admitted to the Social Security Metropolitan Hospital in Panama City between June 1 and October 22, 2006, with unexplained acute kidney injury and a serum creatinine level of greater than or equal to 2 mg/dL, or unexplained chronic renal failure exacerbation (>2-fold increase in baseline serum creatinine level) and history of implicated cough syrup exposure. Main outcomes and measures were demographic, clinical, laboratory, diagnostic, histopathologic, and mortality data with descriptive statistics. Forty-six patients met inclusion criteria. Twenty-four (52%) were female patients; median age was 67 years (range 25 to 91 years). Patients were admitted with acute kidney injury or a chronic renal failure exacerbation (median serum creatinine level 10.0 mg/dL) a median of 5 days after symptom onset. Forty patients (87%; 95% confidence interval [CI] 74% to 95%) had neurologic signs, including limb (n=31; 77%; 95% CI 62% to 89%) or facial motor weakness (n=27; 68%; 95% CI 51% to 81%). Electrodiagnostics in 21 patients with objective weakness demonstrated a severe sensorimotor peripheral neuropathy (n=19; 90%; 95% CI 70% to 99%). In 14 patients without initial neurologic findings, elevated cerebrospinal fluid protein concentrations without pleocytosis were observed: almost all developed overt neurologic illness (n=13; 93%; 95% CI 66% to 100%). Despite use of intensive care and hemodialysis therapies, 27 (59%) died a median of 19 days (range 2 to 50 days) after presentation. A high proportion of patients with diethylene glycol poisoning developed progressive neurologic signs and symptoms in addition to acute kidney injury. Facial or limb weakness with unexplained acute kidney injury should prompt clinicians to consider diethylene glycol poisoning. Elevated cerebrospinal fluid protein concentrations without pleocytosis among diethylene glycol-exposed persons with acute kidney injury may be a predictor for progressive neurologic illness. Copyright © 2014 American College of Emergency Physicians. Published by Mosby, Inc. All rights reserved. JF - Annals of emergency medicine AU - Sosa, Nestor R AU - Rodriguez, Giselle M AU - Schier, Joshua G AU - Sejvar, James J AD - Gorgas Memorial Institute, Panama City, Panama. ; Social Security Metropolitan Hospital, Panama City, Panama. ; National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA. Electronic address: jschier@cdc.gov. ; National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA. Y1 - 2014/07// PY - 2014 DA - July 2014 SP - 38 EP - 47 VL - 64 IS - 1 KW - Ethylene Glycols KW - 0 KW - diethylene glycol KW - 61BR964293 KW - Abridged Index Medicus KW - Index Medicus KW - Panama -- epidemiology KW - Aged, 80 and over KW - Humans KW - Adult KW - Retrospective Studies KW - Aged KW - Middle Aged KW - Male KW - Female KW - Acute Kidney Injury -- epidemiology KW - Acute Kidney Injury -- chemically induced KW - Neurotoxicity Syndromes -- etiology KW - Ethylene Glycols -- poisoning KW - Neurotoxicity Syndromes -- epidemiology KW - Disease Outbreaks UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1539466803?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annals+of+emergency+medicine&rft.atitle=Clinical%2C+laboratory%2C+diagnostic%2C+and+histopathologic+features+of+diethylene+glycol+poisoning--Panama%2C+2006.&rft.au=Sosa%2C+Nestor+R%3BRodriguez%2C+Giselle+M%3BSchier%2C+Joshua+G%3BSejvar%2C+James+J&rft.aulast=Sosa&rft.aufirst=Nestor&rft.date=2014-07-01&rft.volume=64&rft.issue=1&rft.spage=38&rft.isbn=&rft.btitle=&rft.title=Annals+of+emergency+medicine&rft.issn=1097-6760&rft_id=info:doi/10.1016%2Fj.annemergmed.2013.12.011 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2014-08-25 N1 - Date created - 2014-06-21 N1 - Date revised - 2017-01-14 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1016/j.annemergmed.2013.12.011 ER - TY - JOUR T1 - Physiologic doses of depot-medroxyprogesterone acetate do not increase acute plasma simian HIV viremia or mucosal virus shedding in pigtail macaques AN - 1765975784; PQ0002559431 AB - Objective: Epidemiologic studies remain inconclusive on whether the injectable contraceptive depot-medroxyprogesterone acetate (DMPA) increases mucosal HIV shedding and transmissibility. Nonhuman primate models may help to determine the effects of DMPA on acute HIV replication. Design: We defined a physiologic dose of DMPA in macaques and assessed the impact of DMPA on acute simian HIV (SHIV) replication. Methods: Pigtail macaques received 1-30 mg of DMPA intramuscularly followed by measurements of progesterone and medroxyprogesterone acetate (MPA). Vaginal epithelial thickness, number of cell layers and density of intraepithelial CD3 super(+) cells were measured. The effect of DMPA on SHIV viremia and genital virus shedding was investigated in six pigtail macaques infected during monthly treatment cycles with 3 mg DMPA. Six DMPA-untreated macaques were controls. Results: Plasma MPA concentrations directly correlated with changes in epithelial thickness (correlation = 0.84; P < 0.001) and density of intraepithelial CD3 super(+) cells (correlation = 0.41; P = 0.02). A 3 mg DMPA dose recapitulated plasma MPA concentrations and changes in vaginal epithelial thickness seen in women. DMPA-treated and untreated macaques showed similar peak plasma viremia and RNA area under the curve values over 12 weeks (P = 0.94), although treated macaques had higher odds of having virus being detected in plasma (odds ratio 6.6, P = 0.02). Rectal and vaginal virus shedding was similar between treated and untreated macaques (P = 0.72 and P = 0.53, respectively). Conclusion: In this pigtail macaque model of DMPA and vaginal SHIV infection, we found little or no effect of DMPA on plasma viremia and mucosal virus shedding during acute infection. These results do not support a role of DMPA in increasing mucosal HIV shedding. JF - AIDS AU - Radzio, Jessica AU - Hanley, Krisztina AU - Mitchell, James AU - Ellis, Shanon AU - Deyounks, Frank AU - Jenkins, Leecresia T AU - Hanson, Debra AU - Heneine, Walid AU - Garcia-Lerma, J Gerardo AD - Laboratory Branch, Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, GGarcia-Lerma@cdc.gov Y1 - 2014/06/19/ PY - 2014 DA - 2014 Jun 19 SP - 1431 EP - 1439 PB - Lippincott Williams & Wilkins, Inc, 530 Walnut Street Philadelphia PA 19106-3621 United States VL - 28 IS - 10 SN - 0269-9370, 0269-9370 KW - Health & Safety Science Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - depot-medroxyprogesterone acetate KW - pigtail macaques KW - simian HIV KW - virus shedding KW - Acquired immune deficiency syndrome KW - Rectum KW - Progesterone KW - Replication KW - Macaca KW - Macaca nemestrina KW - Mucosa KW - Animal models KW - Infection KW - Primates KW - Acetic acid KW - RNA KW - Human immunodeficiency virus KW - medroxyprogesterone acetate KW - Vagina KW - CD3 antigen KW - Viremia KW - Contraceptives KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1765975784?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS&rft.atitle=Physiologic+doses+of+depot-medroxyprogesterone+acetate+do+not+increase+acute+plasma+simian+HIV+viremia+or+mucosal+virus+shedding+in+pigtail+macaques&rft.au=Radzio%2C+Jessica%3BHanley%2C+Krisztina%3BMitchell%2C+James%3BEllis%2C+Shanon%3BDeyounks%2C+Frank%3BJenkins%2C+Leecresia+T%3BHanson%2C+Debra%3BHeneine%2C+Walid%3BGarcia-Lerma%2C+J+Gerardo&rft.aulast=Radzio&rft.aufirst=Jessica&rft.date=2014-06-19&rft.volume=28&rft.issue=10&rft.spage=1431&rft.isbn=&rft.btitle=&rft.title=AIDS&rft.issn=02699370&rft_id=info:doi/10.1097%2FQAD.0000000000000294 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Rectum; Progesterone; Replication; Mucosa; Animal models; Infection; Acetic acid; RNA; medroxyprogesterone acetate; Vagina; Viremia; CD3 antigen; Contraceptives; Acquired immune deficiency syndrome; Human immunodeficiency virus; Primates; Macaca; Macaca nemestrina DO - http://dx.doi.org/10.1097/QAD.0000000000000294 ER - TY - JOUR T1 - Rift Valley Fever Virus Encephalitis Is Associated with an Ineffective Systemic Immune Response and Activated T Cell Infiltration into the CNS in an Immunocompetent Mouse Model AN - 1551642287; 20168540 AB - Rift Valley fever virus (RVFV) is a mosquito-borne virus that causes severe disease in people and livestock throughout Africa and the Arabian Peninsula. Human disease is usually self-limiting, but a small proportion of individuals develop fatal encephalitis. The role of the host immune response in determining disease outcome is largely unknown. In order to compare the quality and character of immune responses in nonfatal and fatal cases, we used an attenuated RVFV to inoculate mice by two routes. Subcutaneous inoculation resulted in a subclinical systemic infection that was rapidly cleared due to a robust adaptive response. In contrast, intranasal inoculation stimulated weaker immune responses that failed to control virus replication and culminated in uniformly fatal encephalitis. With many encephalitic viruses, the onset of disease is mediated by changes in blood brain barrier permeability and often, subsequent injury to the CNS by an uncontrolled immune response. However, our results suggest that development of RVFV disease does not depend on either mechanism, but rather results from direct virus-mediated damage in the CNS. Future therapeutic drug design should take into account all possible routes of virus exposure as well as the role of therapies that boost the adaptive response to better combat disease. JF - PLoS Neglected Tropical Diseases AU - Dodd, Kimberly A AU - McElroy, Anita K AU - Jones, Tara L AU - Zaki, Sherif R AU - Nichol, Stuart T AU - Spiropoulou, Christina F AD - Viral Special Pathogens Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America Y1 - 2014/06/12/ PY - 2014 DA - 2014 Jun 12 PB - Public Library of Science, 185 Berry Street San Francisco CA 94107 United States VL - 8 IS - 6 SN - 1935-2727, 1935-2727 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Virology & AIDS Abstracts KW - Central nervous system KW - Human diseases KW - ISW, Arabian Peninsula KW - Blood-brain barrier KW - Disseminated infection KW - Viruses KW - Animal models KW - Rift Valley fever KW - Defence mechanisms KW - Immunosuppressive agents KW - Permeability KW - Lymphocytes T KW - Rift Valley fever virus KW - Rift valleys KW - Drugs KW - Brain injury KW - Replication KW - Therapy KW - Drug development KW - Immunity KW - Encephalitis KW - Livestock KW - Inoculation KW - Africa KW - Immune response KW - V 22350:Immunology KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1551642287?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=PLoS+Neglected+Tropical+Diseases&rft.atitle=Rift+Valley+Fever+Virus+Encephalitis+Is+Associated+with+an+Ineffective+Systemic+Immune+Response+and+Activated+T+Cell+Infiltration+into+the+CNS+in+an+Immunocompetent+Mouse+Model&rft.au=Dodd%2C+Kimberly+A%3BMcElroy%2C+Anita+K%3BJones%2C+Tara+L%3BZaki%2C+Sherif+R%3BNichol%2C+Stuart+T%3BSpiropoulou%2C+Christina+F&rft.aulast=Dodd&rft.aufirst=Kimberly&rft.date=2014-06-12&rft.volume=8&rft.issue=6&rft.spage=&rft.isbn=&rft.btitle=&rft.title=PLoS+Neglected+Tropical+Diseases&rft.issn=19352727&rft_id=info:doi/10.1371%2Fjournal.pntd.0002874 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-08-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Permeability; Central nervous system; Human diseases; Viruses; Therapy; Immunity; Defence mechanisms; Drugs; Rift valleys; Brain injury; Blood-brain barrier; Replication; Disseminated infection; Animal models; Drug development; Rift Valley fever; Immunosuppressive agents; Encephalitis; Livestock; Lymphocytes T; Inoculation; Immune response; Rift Valley fever virus; ISW, Arabian Peninsula; Africa DO - http://dx.doi.org/10.1371/journal.pntd.0002874 ER - TY - CPAPER T1 - Public Health Significance of Pathogens Associated With Premise Plumbing Systems T2 - 2014 Annual Conference of the American Water Works Association (ACE 2014) AN - 1548629156; 6290509 JF - 2014 Annual Conference of the American Water Works Association (ACE 2014) AU - Gargano, Julia AU - Collier, Sarah AU - Adam, Elizabeth Y1 - 2014/06/08/ PY - 2014 DA - 2014 Jun 08 KW - Pathogens KW - Public health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1548629156?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2014+Annual+Conference+of+the+American+Water+Works+Association+%28ACE+2014%29&rft.atitle=Public+Health+Significance+of+Pathogens+Associated+With+Premise+Plumbing+Systems&rft.au=Gargano%2C+Julia%3BCollier%2C+Sarah%3BAdam%2C+Elizabeth&rft.aulast=Gargano&rft.aufirst=Julia&rft.date=2014-06-08&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2014+Annual+Conference+of+the+American+Water+Works+Association+%28ACE+2014%29&rft.issn=&rft_id=info:doi/ L2 - http://www.awwa.org/conferences-education/conferences/annual-conference/program/ace14-online-program.aspx# LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-06-30 N1 - Last updated - 2014-07-28 ER - TY - CPAPER T1 - Detection and Response to Naegleria fowleri in Premise Plumbing and Public Drinking Water Systems in Louisiana T2 - 2014 Annual Conference of the American Water Works Association (ACE 2014) AN - 1548628276; 6290510 JF - 2014 Annual Conference of the American Water Works Association (ACE 2014) AU - Hill, Vincent Y1 - 2014/06/08/ PY - 2014 DA - 2014 Jun 08 KW - Drinking Water KW - USA, Louisiana KW - Drinking water KW - Naegleria fowleri UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1548628276?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2014+Annual+Conference+of+the+American+Water+Works+Association+%28ACE+2014%29&rft.atitle=Detection+and+Response+to+Naegleria+fowleri+in+Premise+Plumbing+and+Public+Drinking+Water+Systems+in+Louisiana&rft.au=Hill%2C+Vincent&rft.aulast=Hill&rft.aufirst=Vincent&rft.date=2014-06-08&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2014+Annual+Conference+of+the+American+Water+Works+Association+%28ACE+2014%29&rft.issn=&rft_id=info:doi/ L2 - http://www.awwa.org/conferences-education/conferences/annual-conference/program/ace14-online-program.aspx# LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-06-30 N1 - Last updated - 2014-07-28 ER - TY - JOUR T1 - Discordance between Self-Report and Genetic Confirmation of Sickle Cell Disease Status in African-American Adults AN - 1773904854; PQ0002708294 AB - Background: Sickle cell disease (SCD) is an autosomal recessive genetic disorder, with persons heterozygous for the mutation said to have the sickle cell trait (SCT). Serious adverse effects are mainly limited to those with SCD, but the distinction between disease and trait is not always clear to the general population. We sought to determine the accuracy of self-reported SCD when compared to genetic confirmation. Methods: From stratified random samples of Southern Community Cohort Study participants, we sequenced the - globin gene in 51 individuals reporting SCD and 75 individuals reporting no SCD. Results: The median age of the group selected was 53 years (range 40-69) with 29% male. Only 5.9% of the 51 individuals reporting SCD were confirmed by sequencing, with the remaining 62.7% having SCT, 5.9% having hemoglobin C trait, and 25.5% having neither SCD nor trait. Sequencing results of the 75 individuals reporting no SCD by contrast were 100% concordant with self-report. Conclusions: Misreporting of SCD is common in an older adult population, with most persons reporting SCD in this study being carriers of the trait and a sizeable minority completely unaffected. The results from this pilot survey support the need for increased efforts to raise community awareness and knowledge of SCD. copyright 2014 S. Karger AG, Basel JF - Public Health Genomics AU - Bean, Christopher J AU - Hooper, WCraig AU - Ellingsen, Dorothy AU - DeBaun, Michael R AU - Sonderman, Jennifer AU - Blot, William J AD - Division of Blood Disorders, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Ga. Y1 - 2014/06// PY - 2014 DA - June 2014 SP - 169 EP - 172 PB - S. Karger AG, P.O. Box Basel CH-4009 Switzerland VL - 17 IS - 3 SN - 1662-4246, 1662-4246 KW - Genetics Abstracts; Health & Safety Science Abstracts KW - Genetic communication KW - Health literacy KW - Hemoglobin KW - Self-report KW - Sickle cell disease KW - Age KW - Hereditary diseases KW - Public health KW - Discordance KW - Age groups KW - Mutation KW - Ethnic groups KW - Side effects KW - H 12000:Epidemiology and Public Health KW - G 07730:Development & Cell Cycle UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1773904854?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Public+Health+Genomics&rft.atitle=Discordance+between+Self-Report+and+Genetic+Confirmation+of+Sickle+Cell+Disease+Status+in+African-American+Adults&rft.au=Bean%2C+Christopher+J%3BHooper%2C+WCraig%3BEllingsen%2C+Dorothy%3BDeBaun%2C+Michael+R%3BSonderman%2C+Jennifer%3BBlot%2C+William+J&rft.aulast=Bean&rft.aufirst=Christopher&rft.date=2014-06-01&rft.volume=17&rft.issue=3&rft.spage=169&rft.isbn=&rft.btitle=&rft.title=Public+Health+Genomics&rft.issn=16624246&rft_id=info:doi/10.1159%2F000360260 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-03-01 N1 - Last updated - 2016-09-14 N1 - SubjectsTermNotLitGenreText - Hemoglobin; Age; Hereditary diseases; Discordance; Mutation; Sickle cell disease; Side effects; Public health; Age groups; Ethnic groups DO - http://dx.doi.org/10.1159/000360260 ER - TY - JOUR T1 - Identification of Risk Factors for Plague in the West Nile Region of Uganda AN - 1647015521; 21189924 AB - Plague is an often fatal, primarily flea-borne rodent-associated zoonosis caused by Yersinia pestis. We sought to identify risk factors for plague by comparing villages with and without a history of human plague cases within a model-defined plague focus in the West Nile Region of Uganda. Although rat (Rattus rattus) abundance was similar inside huts within case and control villages, contact rates between rats and humans (as measured by reported rat bites) and host-seeking flea loads were higher in case villages. In addition, compared with persons in control villages, persons in case villages more often reported sleeping on reed or straw mats, storing food in huts where persons sleep, owning dogs and allowing them into huts where persons sleep, storing garbage inside or near huts, and cooking in huts where persons sleep. Compared with persons in case villages, persons in control villages more commonly reported replacing thatch roofing, and growing coffee, tomatoes, onions, and melons in agricultural plots adjacent to their homesteads. Rodent and flea control practices, knowledge of plague, distance to clinics, and most care-seeking practices were similar between persons in case villages and persons in control villages. Our findings reinforce existing plague prevention recommendations and point to potentially advantageous local interventions. JF - American Journal of Tropical Medicine and Hygiene AU - Eisen, Rebecca J AU - MacMillan, Katherine AU - Atiku, Linda A AU - Mpanga, Joseph T AU - Zielinski-Gutierrez, Emily AU - Graham, Christine B AU - Boegler, Karen A AU - Enscore, Russell E AU - Gage, Kenneth L AD - Uganda Virus Research Institute, Entebbe, Uganda; Bacterial Diseases Branch, Division of Vector Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, PO Box 2087, Fort Collins, CO 80522, dyn2@cdc.gov Y1 - 2014/06// PY - 2014 DA - June 2014 SP - 1047 EP - 1058 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 90 IS - 6 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Coffee KW - Bites KW - Food KW - Abundance KW - Yersinia pestis KW - Uganda KW - Rattus rattus KW - Risks KW - Lycopersicon esculentum KW - Risk factors KW - Sleep KW - Cooking KW - Allium cepa KW - Plague KW - Straw KW - Hygiene KW - K 03410:Animal Diseases KW - J 02410:Animal Diseases KW - Q1 08485:Species interactions: pests and control KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1647015521?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Identification+of+Risk+Factors+for+Plague+in+the+West+Nile+Region+of+Uganda&rft.au=Eisen%2C+Rebecca+J%3BMacMillan%2C+Katherine%3BAtiku%2C+Linda+A%3BMpanga%2C+Joseph+T%3BZielinski-Gutierrez%2C+Emily%3BGraham%2C+Christine+B%3BBoegler%2C+Karen+A%3BEnscore%2C+Russell+E%3BGage%2C+Kenneth+L&rft.aulast=Eisen&rft.aufirst=Rebecca&rft.date=2014-06-01&rft.volume=90&rft.issue=6&rft.spage=1047&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.14-0035 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Sleep; Hygiene; Risks; Coffee; Bites; Food; Risk factors; Cooking; Abundance; Straw; Plague; Lycopersicon esculentum; Allium cepa; Yersinia pestis; Rattus rattus; Uganda DO - http://dx.doi.org/10.4269/ajtmh.14-0035 ER - TY - JOUR T1 - Viruses Associated With Acute Respiratory Infections and Influenza-like Illness Among Outpatients From the Influenza Incidence Surveillance Project, 2010-2011 AN - 1618152439; 20800402 AB - Background. The Influenza Incidence Surveillance Project (IISP) monitored outpatient acute respiratory infection (ARI; defined as the presence of > or =2 respiratory symptoms not meeting ILI criteria) and influenza-like illness (ILI) to determine the incidence and contribution of associated viral etiologies. Methods. From August 2010 through July 2011, 57 outpatient healthcare providers in 12 US sites reported weekly the number of visits for ILI and ARI and collected respiratory specimens on a subset for viral testing. The incidence was estimated using the number of patients in the practice as the denominator, and the virus-specific incidence of clinic visits was extrapolated from the proportion of patients testing positive. Results. The age-adjusted cumulative incidence of outpatient visits for ARI and ILI combined was 95/1000 persons, with a viral etiology identified in 58% of specimens. Most frequently detected were rhinoviruses/enteroviruses (RV/EV) (21%) and influenza viruses (21%); the resulting extrapolated incidence of outpatient visits was 20 and 19/1000 persons respectively. The incidence of influenza virus-associated clinic visits was highest among patients aged 2-17 years, whereas other viruses had varied patterns among age groups. Conclusions. The IISP provides a unique opportunity to estimate the outpatient respiratory illness burden by etiology. Influenza virus infection and RV/EV infection(s) represent a substantial burden of respiratory disease in the US outpatient setting, particularly among children. JF - Journal of Infectious Diseases AU - Fowlkes, Ashley AU - Giorgi, Andrea AU - Erdman, Dean AU - Temte, Jon AU - Goodin, Kate AU - Di Lonardo, Steve AU - Sun, Yumei AU - Martin, Karen AU - Feist, Michelle AU - Linz, Rachel AD - Influenza Division, afowlkes@cdc.gov Y1 - 2014/06/01/ PY - 2014 DA - 2014 Jun 01 SP - 1715 EP - 1725 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 209 IS - 11 SN - 0022-1899, 0022-1899 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - influenza KW - respiratory virus KW - influenza-like illness KW - acute respiratory illness KW - seasonality KW - epidemiology KW - Etiology KW - Age KW - Viruses KW - Respiratory diseases KW - Infection KW - Children KW - Medical personnel KW - Influenza KW - Influenza virus KW - Infectious diseases KW - Rhinovirus KW - Age groups KW - H 1000:Occupational Safety and Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1618152439?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Viruses+Associated+With+Acute+Respiratory+Infections+and+Influenza-like+Illness+Among+Outpatients+From+the+Influenza+Incidence+Surveillance+Project%2C+2010-2011&rft.au=Fowlkes%2C+Ashley%3BGiorgi%2C+Andrea%3BErdman%2C+Dean%3BTemte%2C+Jon%3BGoodin%2C+Kate%3BDi+Lonardo%2C+Steve%3BSun%2C+Yumei%3BMartin%2C+Karen%3BFeist%2C+Michelle%3BLinz%2C+Rachel&rft.aulast=Fowlkes&rft.aufirst=Ashley&rft.date=2014-06-01&rft.volume=209&rft.issue=11&rft.spage=1715&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjit806 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-10-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Influenza; Age; Etiology; Children; Infection; Infectious diseases; Viruses; Age groups; Respiratory diseases; Medical personnel; Influenza virus; Rhinovirus DO - http://dx.doi.org/10.1093/infdis/jit806 ER - TY - JOUR T1 - Persistence of serogroup C antibody responses following quadrivalent meningococcal conjugate vaccination in United States military personnel AN - 1555015569; 20451622 AB - Serogroup C meningococcal (MenC) disease accounts for one-third of all meningococcal cases and causes meningococcal outbreaks in the U.S. Quadrivalent meningococcal vaccine conjugated to diphtheria toxoid (MenACYWD) was recommended in 2005 for adolescents and high risk groups such as military recruits. We evaluated anti-MenC antibody persistence in U.S. military personnel vaccinated with either MenACYWD or meningococcal polysaccharide vaccine (MPSV4). Twelve hundred subjects vaccinated with MenACYWD from 2006 to 2008 or MPSV4 from 2002 to 2004 were randomly selected from the Defense Medical Surveillance System. Baseline serologic responses to MenC were assessed in all subjects; 100 subjects per vaccine group were tested during one of the following six post-vaccination time-points: 5-7, 11-13, 17-19, 23-25, 29-31, or 35-37 months. Anti-MenC geometric mean titers (GMT) were measured by rabbit complement serum bactericidal assay (rSBA) and geometric mean concentrations (GMC) by enzyme-linked immunosorbent assay (ELISA). Continuous variables were compared using the Wilcoxon rank sum test and the proportion of subjects with an rSBA titer greater than or equal to 8 by chi-square. Pre-vaccination rSBA GMT was <8 for the MenACWYD group. rSBA GMT increased to 703 at 5-7 months post-vaccination and decreased by 94% to 43 at 3 years post-vaccination. GMT was significantly lower in the MenACWYD group at 5-7 months post-vaccination compared to the MPSV4 group. The percentage of MenACWYD recipients achieving an rSBA titer of greater than or equal to 8 decreased from 87% at 5-7 months to 54% at 3 years. There were no significant differences between vaccine groups in the proportion of subjects with a titer of greater than or equal to 8 at any time-point. GMC for the MenACWYD group was 0.14 mu g/mL at baseline, 1.07 mu g/mL at 5-7 months, and 0.66 mu g/mL at 3 years, and significantly lower than the MPSV4 group at all time-points. Anti-MenC responses wane following vaccination with MenACYWD; a booster dose is needed to maintain protective levels of circulating antibody. JF - Vaccine AU - Patel, Manisha AU - Romero-Steiner, Sandra AU - Broderick, Michael P AU - Thomas, Cynthia G AU - Plikaytis, Brian D AU - Schmidt, Daniel S AU - Johnson, Scott E AU - Milton, Andrea S AU - Carlone, George M AU - Clark, Thomas A AU - Messonnier, Nancy E AU - Cohn, Amanda C AU - Faix, Dennis J AD - Meningitis and Vaccine-Preventable Diseases Branch, Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, MS C-25, Atlanta, GA 30333, USA Y1 - 2014/06// PY - 2014 DA - Jun 2014 SP - 3805 EP - 3809 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 32 IS - 30 SN - 0264-410X, 0264-410X KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - ACIP Advisory Committee on Immunization Practices KW - CDC Centers for Disease Control and Prevention KW - DMSS Defense Medical Surveillance System KW - DoD Department of Defense KW - DoDSR Department of Defense Serum Repository KW - ELISA enzyme-linked immunosorbent assay KW - GMC geometric mean concentration KW - GMT geometric mean titer KW - LLQ lower limit of quantitation KW - MenACYW quadrivalent meningococcal conjugate vaccine KW - MenACYWD quadrivalent meningococcal conjugate vaccine conjugated to diphtheria toxoid KW - MenC Serogroup C KW - MPSV4 quadrivalent meningococcal polysaccharide vaccine KW - NHRC Naval Health Research Center KW - rSBA rabbit complement serum bactericidal assay KW - VE vaccine effectiveness KW - Meningococcal vaccine KW - Conjugate KW - Polysaccharide KW - Antibody persistence KW - Antibodies KW - Enzyme-linked immunosorbent assay KW - Adolescence KW - Risk groups KW - Neisseria meningitidis KW - Vaccines KW - Toxoids KW - Diphtheria KW - Polysaccharides KW - Vaccination KW - Military personnel KW - F 06905:Vaccines KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1555015569?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Persistence+of+serogroup+C+antibody+responses+following+quadrivalent+meningococcal+conjugate+vaccination+in+United+States+military+personnel&rft.au=Patel%2C+Manisha%3BRomero-Steiner%2C+Sandra%3BBroderick%2C+Michael+P%3BThomas%2C+Cynthia+G%3BPlikaytis%2C+Brian+D%3BSchmidt%2C+Daniel+S%3BJohnson%2C+Scott+E%3BMilton%2C+Andrea+S%3BCarlone%2C+George+M%3BClark%2C+Thomas+A%3BMessonnier%2C+Nancy+E%3BCohn%2C+Amanda+C%3BFaix%2C+Dennis+J&rft.aulast=Patel&rft.aufirst=Manisha&rft.date=2014-06-01&rft.volume=32&rft.issue=30&rft.spage=3805&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/10.1016%2Fj.vaccine.2014.05.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-08-01 N1 - Last updated - 2014-11-12 N1 - SubjectsTermNotLitGenreText - Enzyme-linked immunosorbent assay; Antibodies; Adolescence; Risk groups; Diphtheria; Toxoids; Vaccines; Polysaccharides; Vaccination; Military personnel; Neisseria meningitidis DO - http://dx.doi.org/10.1016/j.vaccine.2014.05.001 ER - TY - JOUR T1 - Modeling the potential impact of vaccination on the epidemiology of congenital cytomegalovirus infection AN - 1555013997; 20451615 AB - Background Understanding the potential for vaccination to change cytomegalovirus (CMV) epidemiology is important for developing CMV vaccines and designing clinical trials. Methods We constructed a deterministic, age-specific and time-dependent mathematical model of pathogen transmission, parameterized using CMV seroprevalence from the United States and Brazil, to predict the impact of vaccination on congenital CMV infection. Findings Concurrent vaccination of young children and adolescents would result in the greatest reductions in congenital CMV infections in populations with moderate and high baseline maternal seroprevalence. Such a vaccination strategy, assuming 70% vaccine efficacy, 90% coverage and 5-year duration of protection, could ultimately prevent 30-50% of congenital CMV infections. At equilibrium, this strategy could result in a 30% reduction in congenital CMV infections due to primary maternal infection in the United States but a 3% increase in Brazil. The potential for an increase in congenital CMV infections due to primary maternal infections in Brazil was not predicted with use of a vaccine that confers protection for greater than 5 years. Interpretation Modeling suggests that vaccination strategies that include young children will result in greater declines in congenital CMV infection than those restricted to adolescents or women of reproductive age. Our study highlights the critical need for better understanding of the relative contribution of type of maternal infection to congenital CMV infection and disease, the main focus of vaccine prevention. JF - Vaccine AU - Lanzieri, Tatiana M AU - Bialek, Stephanie R AU - Ortega-Sanchez, Ismael R AU - Gambhir, Manoj AD - National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA Y1 - 2014/06// PY - 2014 DA - Jun 2014 SP - 3780 EP - 3786 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 32 IS - 30 SN - 0264-410X, 0264-410X KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts; Immunology Abstracts KW - Cytomegalovirus KW - Congenital infection KW - Vaccination impact KW - Mathematical model KW - Age KW - Mathematical models KW - Adolescence KW - Pathogens KW - Infection KW - Children KW - Clinical trials KW - USA KW - Prevention KW - Epidemiology KW - Brazil KW - Vaccines KW - Adolescents KW - F 06905:Vaccines KW - V 22400:Human Diseases KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1555013997?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Modeling+the+potential+impact+of+vaccination+on+the+epidemiology+of+congenital+cytomegalovirus+infection&rft.au=Lanzieri%2C+Tatiana+M%3BBialek%2C+Stephanie+R%3BOrtega-Sanchez%2C+Ismael+R%3BGambhir%2C+Manoj&rft.aulast=Lanzieri&rft.aufirst=Tatiana&rft.date=2014-06-01&rft.volume=32&rft.issue=30&rft.spage=3780&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/10.1016%2Fj.vaccine.2014.05.014 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-08-01 N1 - Last updated - 2014-12-11 N1 - SubjectsTermNotLitGenreText - Age; Mathematical models; Epidemiology; Adolescence; Pathogens; Vaccines; Children; Infection; Clinical trials; Prevention; Adolescents; Cytomegalovirus; USA; Brazil DO - http://dx.doi.org/10.1016/j.vaccine.2014.05.014 ER - TY - JOUR T1 - Concordance between Molecular and Phenotypic Testing of Mycobacterium tuberculosis Complex Isolates for Resistance to Rifampin and Isoniazid in the United States AN - 1540240512; 19990248 AB - Multidrug-resistant (MDR) isolates of Mycobacterium tuberculosis complex (MTBC) are defined by resistance to at least rifampin (RMP) and isoniazid (INH). Rapid and accurate detection of multidrug resistance is essential for effective treatment and interruption of disease transmission of tuberculosis (TB). Overdiagnosis of MDR TB may result in treatment with second-line drugs that are more costly, less effective, and more poorly tolerated than first-line drugs. CDC offers rapid confirmation of MDR TB by the molecular detection of drug resistance (MDDR) for mutations associated with resistance to RMP and INH along with analysis for resistance to other first-line and second-line drugs. Simultaneously, CDC does growth-based phenotypic drug susceptibility testing (DST) by the indirect agar proportion method for a panel of first-line and second-line antituberculosis drugs. We reviewed discordance between molecular and phenotypic DST for INH and RMP for 285 isolates submitted as MTBC to CDC from September 2009 to February 2011. We compared CDC's results with those from the submitting public health laboratories (PHL). Concordances between molecular and phenotypic testing at CDC were 97.4% for RMP and 92.5% for INH resistance. Concordances between CDC's molecular testing and PHL DST results were 93.9% for RMP and 90.0% for INH. Overall concordance between CDC molecular and PHL DST results was 91.7% for RMP and INH collectively. Discordance was primarily attributable to the absence of known INH resistance mutations in isolates found to be INH resistant by DST and detection of mutations associated with low-level RMP resistance in isolates that were RMP susceptible by phenotypic DST. Both molecular and phenotypic test results should be considered for the diagnosis of MDR TB. JF - Journal of Clinical Microbiology AU - Yakrus, Mitchell A AU - Driscoll, Jeffrey AU - Lentz, Allison J AU - Sikes, David AU - Hartline, Denise AU - Metchock, Beverly AU - Starks, Angela M Y1 - 2014/06// PY - 2014 DA - June 2014 SP - 1932 EP - 1937 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 52 IS - 6 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Agar KW - Drug resistance KW - Public health KW - Disease transmission KW - Rifampin KW - Reviews KW - Discordance KW - Tuberculosis KW - Multidrug resistance KW - Mutation KW - Mycobacterium tuberculosis KW - Isoniazid KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1540240512?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Concordance+between+Molecular+and+Phenotypic+Testing+of+Mycobacterium+tuberculosis+Complex+Isolates+for+Resistance+to+Rifampin+and+Isoniazid+in+the+United+States&rft.au=Yakrus%2C+Mitchell+A%3BDriscoll%2C+Jeffrey%3BLentz%2C+Allison+J%3BSikes%2C+David%3BHartline%2C+Denise%3BMetchock%2C+Beverly%3BStarks%2C+Angela+M&rft.aulast=Yakrus&rft.aufirst=Mitchell&rft.date=2014-06-01&rft.volume=52&rft.issue=6&rft.spage=1932&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.00417-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-06-01 N1 - Number of references - 12 N1 - Last updated - 2016-07-20 N1 - SubjectsTermNotLitGenreText - Agar; Rifampin; Reviews; Drug resistance; Discordance; Multidrug resistance; Tuberculosis; Mutation; Disease transmission; Public health; Isoniazid; Mycobacterium tuberculosis DO - http://dx.doi.org/10.1128/JCM.00417-14 ER - TY - JOUR T1 - Acute Sinusitis and Pharyngitis as Inappropriate Indications for Antibiotic Use AN - 1534854497; 19968385 JF - Antimicrobial Agents & Chemotherapy AU - Sanchez, Guillermo V AU - Hicks, Lauri A Y1 - 2014/06// PY - 2014 DA - Jun 2014 SP - 3572 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 58 IS - 6 SN - 0066-4804, 0066-4804 KW - Microbiology Abstracts A: Industrial & Applied Microbiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1534854497?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Acute+Sinusitis+and+Pharyngitis+as+Inappropriate+Indications+for+Antibiotic+Use&rft.au=Sanchez%2C+Guillermo+V%3BHicks%2C+Lauri+A&rft.aulast=Sanchez&rft.aufirst=Guillermo&rft.date=2014-06-01&rft.volume=58&rft.issue=6&rft.spage=3572&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.02696-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-06-01 N1 - Number of references - 4 N1 - Last updated - 2014-06-12 DO - http://dx.doi.org/10.1128/AAC.02696-14 ER - TY - JOUR T1 - Effectiveness of typhoid vaccination in US travelers AN - 1534849674; 20048145 AB - Typhoid vaccination is recommended in the United States before travel to countries where typhoid fever is endemic, though little information is available on its effectiveness in travelers. We estimated typhoid vaccination effectiveness (VE) by comparing vaccination status in cases of typhoid fever and paratyphoid fever (Salmonella Paratyphi A infection, against which typhoid vaccine offers no protection) reported in the United States. We included travelers to Southern Asia and excluded persons <2 years old and cases in which vaccination status was not reported. From 2008 through 2011, 744 eligible cases (602 typhoid, 142 paratyphoid A) were reported to CDC. Typhoid vaccination was reported for 5% (29/602) of typhoid patients and for 20% (29/142) of paratyphoid A patients. Estimated VE was 80% (95% confidence interval, 66-89%). Because of missing data, we could not estimate VE for specific vaccines. We demonstrated moderate effectiveness of typhoid vaccination in US travelers, supporting vaccination recommendations. JF - Vaccine AU - Mahon, Barbara E AU - Newton, Anna E AU - Mintz, Eric D AD - Enteric Diseases Epidemiology Branch, Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Mailstop C-09, 1600 Clifton Road, Atlanta, GA 30030, USA Y1 - 2014/06// PY - 2014 DA - Jun 2014 SP - 3577 EP - 3579 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 32 IS - 29 SN - 0264-410X, 0264-410X KW - Health & Safety Science Abstracts; Immunology Abstracts KW - Typhoid vaccination KW - Vaccination effectiveness KW - United States KW - Travelers KW - Travel KW - Data processing KW - Infection KW - USA KW - Salmonella paratyphi KW - Vaccines KW - Asia KW - Typhoid fever KW - Paratyphoid fever KW - F 06905:Vaccines KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1534849674?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Effectiveness+of+typhoid+vaccination+in+US+travelers&rft.au=Mahon%2C+Barbara+E%3BNewton%2C+Anna+E%3BMintz%2C+Eric+D&rft.aulast=Mahon&rft.aufirst=Barbara&rft.date=2014-06-01&rft.volume=32&rft.issue=29&rft.spage=3577&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/10.1016%2Fj.vaccine.2014.04.055 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-06-01 N1 - Last updated - 2014-09-18 N1 - SubjectsTermNotLitGenreText - Travel; Data processing; Vaccines; Paratyphoid fever; Infection; Typhoid fever; Salmonella paratyphi; USA; Asia DO - http://dx.doi.org/10.1016/j.vaccine.2014.04.055 ER - TY - JOUR T1 - Inhibitors of the Tick-Borne, Hemorrhagic Fever-Associated Flaviviruses AN - 1534834658; 19968357 AB - No antiviral therapies are available for the tick-borne flaviviruses associated with hemorrhagic fevers: Kyasanur Forest disease virus (KFDV), both classical and the Alkhurma hemorrhagic fever virus (AHFV) subtype, and Omsk hemorrhagic fever virus (OHFV). We tested compounds reported to have antiviral activity against members of the Flaviviridae family for their ability to inhibit AHFV replication. 6-Azauridine (6-azaU), 2'-C-methylcytidine (2'-CMC), and interferon alpha 2a (IFN- alpha 2a) inhibited the replication of AHFV and also KFDV, OHFV, and Powassan virus. The combination of IFN- alpha 2a and 2'-CMC exerted an additive antiviral effect on AHFV, and the combination of IFN- alpha 2a and 6-azaU was moderately synergistic. The combination of 2'-CMC and 6-azaU was complex, being strongly synergistic but with a moderate level of antagonism. The antiviral activity of 6-azaU was reduced by the addition of cytidine but not guanosine, suggesting that it acted by inhibiting pyrimidine biosynthesis. To investigate the mechanism of action of 2'-CMC, AHFV variants with reduced susceptibility to 2'-CMC were selected. We used a replicon system to assess the substitutions present in the selected AHFV population. A double NS5 mutant, S603T/C666S, and a triple mutant, S603T/C666S/M644V, were more resistant to 2'-CMC than the wild-type replicon. The S603T/C666S mutant had a reduced level of replication which was increased when M644V was also present, although the replication of this triple mutant was still below that of the wild type. The S603 and C666 residues were predicted to lie in the active site of the AHFV NS5 polymerase, implicating the catalytic center of the enzyme as the binding site for 2'-CMC. JF - Antimicrobial Agents & Chemotherapy AU - Flint, Mike AU - McMullan, Laura K AU - Dodd, Kimberly A AU - Bird, Brian H AU - Khristova, Marina L AU - Nichol, Stuart T AU - Spiropoulou, Christina F AD - Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, ccs8@cdc.gov. Y1 - 2014/06// PY - 2014 DA - Jun 2014 SP - 3206 EP - 3216 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 58 IS - 6 SN - 0066-4804, 0066-4804 KW - Virology & AIDS Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Replication KW - Powassan virus KW - Enzymes KW - Antagonism KW - Omsk hemorrhagic fever virus KW - Antiviral activity KW - Hemorrhage KW - Kyasanur forest disease virus KW - Flaviviridae KW - 6-Azauridine KW - alpha -Interferon KW - Hemorrhagic fever KW - pyrimidines KW - Guanosine KW - Omsk hemorrhagic fever KW - V 22320:Replication KW - A 01390:Forestry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1534834658?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Inhibitors+of+the+Tick-Borne%2C+Hemorrhagic+Fever-Associated+Flaviviruses&rft.au=Flint%2C+Mike%3BMcMullan%2C+Laura+K%3BDodd%2C+Kimberly+A%3BBird%2C+Brian+H%3BKhristova%2C+Marina+L%3BNichol%2C+Stuart+T%3BSpiropoulou%2C+Christina+F&rft.aulast=Flint&rft.aufirst=Mike&rft.date=2014-06-01&rft.volume=58&rft.issue=6&rft.spage=3206&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.02393-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-06-01 N1 - Number of references - 48 N1 - Last updated - 2014-10-02 N1 - SubjectsTermNotLitGenreText - Replication; alpha -Interferon; pyrimidines; Enzymes; Hemorrhagic fever; Omsk hemorrhagic fever; Antagonism; Guanosine; Hemorrhage; Antiviral activity; 6-Azauridine; Powassan virus; Omsk hemorrhagic fever virus; Kyasanur forest disease virus; Flaviviridae DO - http://dx.doi.org/10.1128/AAC.02393-14 ER - TY - JOUR T1 - Prevalence and Public Health Implications of State Laws that Criminalize Potential HIV Exposure in the United States AN - 1529937780; 19902563 AB - For the past three decades, legislative approaches to prevent HIV transmission have been used at the national, state, and local levels. One punitive legislative approach has been enactment of laws that criminalize behaviors associated with HIV exposure (HIV-specific criminal laws). In the USA, HIV-specific criminal laws have largely been shaped by state laws. These laws impose criminal penalties on persons who know they have HIV and subsequently engage in certain behaviors, most commonly sexual activity without prior disclosure of HIV-positive serostatus. These laws have been subject to intense public debate. Using public health law research methods, data from the legal database WestlawNext copyright were analyzed to describe the prevalence and characteristics of laws that criminalize potential HIV exposure in the 50 states (plus the District of Columbia) and to examine the implications of these laws for public health practice. The first state laws were enacted in 1986; as of 2011 a total of 67 laws had been enacted in 33 states. By 1995, nearly two-thirds of all laws had been enacted; by 2000, 85 % of laws had been enacted; and since 2000, an additional 10 laws have been enacted. Twenty-four states require persons who are aware that they have HIV to disclose their status to sexual partners and 14 states require disclosure to needle-sharing partners. Twenty-five states criminalize one or more behaviors that pose a low or negligible risk for HIV transmission. Nearly two-thirds of states in the USA have legislation that criminalizes potential HIV exposure. Many of these laws criminalize behaviors that pose low or negligible risk for HIV transmission. The majority of laws were passed before studies showed that antiretroviral therapy (ART) reduces HIV transmission risk and most laws do not account for HIV prevention measures that reduce transmission risk, such as condom use, ART, or pre-exposure prophylaxis. States with HIV-specific criminal laws are encouraged to use the findings of this paper to re-examine those laws, assess the laws' alignment with current evidence regarding HIV transmission risk, and consider whether the laws are the best vehicle to achieve their intended purposes.Original Abstract: Durante las ultimas tres decadas, se han utilizado a nivel nacional, estatal y local enfoques legislativos para prevenir la transmision del VIH. Un enfoque legislativo punitivo ha sido la promulgacion de leyes que criminalizan conductas asociadas a la exposicion al VIH (leyes criminales especificamente relacionadas con el VIH). En los Estados Unidos, las leyes criminales especificamente relacionadas con el VIH han sido en gran medida influenciadas por leyes estatales. Estas leyes imponen sanciones criminales a las personas que saben que tienen el VIH y posteriormente participan en ciertos comportamientos o conductas, frecuentemente la actividades sexuales, sin la divulgacion previa del estado serologico del VIH. Estas leyes han sido objeto de un intenso debate publico. Utilizando metodos de investigacion de la ley de salud publica, datos obtenidos de la base de datos legal WestlawNext[copy fueron analizados para describir la prevalencia y las caracteristicas de las leyes que criminalizan la posible exposicion al VIH en los 50 estados de los Estados Unidos y el Distrito de Columbia y examinar las implicaciones de estas leyes en la practica de salud publica. Las primeras leyes estatales fueron promulgadas en 1986; para el ano 2011, un total de 67 leyes se habian promulgado en 33 estados. Para el ano 1995, casi dos tercios de todas las leyes habian sido aprobadas; para el ano 2000, el 85 % de las leyes habian sido aprobadas; y desde el ano 2000, se han aprobado otras 10 leyes adicionales. Veinticuatro estados requieren que las personas que saben que tienen el VIH revelen su condicion a sus parejas sexuales y 14 estados requieren divulgacion de la condicion del VIH a las parejas con quien comparten agujas. Veinticinco estados criminalizan uno o mas comportamientos que representan un riesgo bajo o insignificante para la transmision del VIH. Casi dos tercios de los estados de los Estados Unidos han promulgado legislacion que criminalizan la posible exposicion al VIH. Muchas de estas leyes penalizan conductas que representan un riesgo bajo o insignificante para la transmision del VIH. La mayoria de estas leyes se aprobaron antes de que investigaciones conducidas demostraran que la terapia antirretroviral (ART, por sus siglas en ingles) reduce el riesgo de transmision del VIH y la mayoria no toman en consideracion medidas de prevencion que reducen el riesgo de transmision del VIH, tales como el uso del condon, ART, o la profilaxis pre-exposicion (PrEP). Se exhorta a los estados que han aprobado leyes criminales especificamente relacionadas con el VIH a utilizar los hallazgos de este trabajo para reexaminar las leyes vigentes, evaluar la alineacion de las leyes con la evidencia actual con respecto al riesgo de transmision del VIH, y considerar si estas leyes son el mejor vehiculo para lograr los fines previstos. JF - AIDS and Behavior AU - Lehman, JStan AU - Carr, Meredith H AU - Nichol, Allison J AU - Ruisanchez, Alberto AU - Knight, David W AU - Langford, Anne E AU - Gray, Simone C AU - Mermin, Jonathan H AD - Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Rd, MS-D21, 30333, Atlanta, Georgia, slehman@cdc.gov Y1 - 2014/06// PY - 2014 DA - Jun 2014 SP - 997 EP - 1006 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 18 IS - 6 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - Risk assessment KW - Acquired immune deficiency syndrome KW - Risk taking KW - Sexual behavior KW - Disease transmission KW - Public health KW - Condoms KW - Sexual partners KW - Research methods KW - Risk factors KW - Data processing KW - antiretroviral therapy KW - Antiretroviral agents KW - Databases KW - USA KW - Prevention KW - Human immunodeficiency virus KW - Prophylaxis KW - Legislation KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1529937780?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Prevalence+and+Public+Health+Implications+of+State+Laws+that+Criminalize+Potential+HIV+Exposure+in+the+United+States&rft.au=Lehman%2C+JStan%3BCarr%2C+Meredith+H%3BNichol%2C+Allison+J%3BRuisanchez%2C+Alberto%3BKnight%2C+David+W%3BLangford%2C+Anne+E%3BGray%2C+Simone+C%3BMermin%2C+Jonathan+H&rft.aulast=Lehman&rft.aufirst=JStan&rft.date=2014-06-01&rft.volume=18&rft.issue=6&rft.spage=997&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-014-0724-0 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-05-01 N1 - Number of references - 38 N1 - Last updated - 2014-06-26 N1 - SubjectsTermNotLitGenreText - Sexual partners; Condoms; Databases; Data processing; Risk factors; antiretroviral therapy; Prophylaxis; Sexual behavior; Legislation; Public health; Disease transmission; Risk assessment; Acquired immune deficiency syndrome; Risk taking; Antiretroviral agents; Prevention; Research methods; Human immunodeficiency virus; USA DO - http://dx.doi.org/10.1007/s10461-014-0724-0 ER - TY - JOUR T1 - Sexual risk behaviour and viral suppression among HIV-infected adults receiving medical care in the United States AN - 1765980340; PQ0002610784 AB - Objective: To describe the prevalence and association of sexual risk behaviours and viral suppression among HIV-infected adults in the United States. Design: Cross-sectional analysis of weighted data from a probability sample of HIVinfected adults receiving outpatient medical care. The facility and patient response rates were 76 and 51%, respectively. Methods: We analysed 2009 interview and medical record data. Sexual behaviours were self-reported in the past 12 months. Viral suppression was defined as all viral load measurements in the medical record during the past 12 months less than 200copies/ml. Results: An estimated 98 022 (24%) HIV-infected adults engaged in unprotected vaginal or anal sex; 50 953 (12%) engaged in unprotected vaginal or anal sex with at least one partner of negative or unknown HIV status; 23 933 (6%) did so while not virally suppressed. Persons who were virally suppressed were less likely than persons who were not suppressed to engage in vaginal or anal sex [prevalence ratio, 0.88; 95% confidence interval (Cl), 0.82-0.93]; unprotected vaginal or anal sex (prevalence ratio, 0.85; 95% Cl, 0.73-0.98); and unprotected vaginal or anal sex with a partner of negative or unknown HIV status (prevalence ratio, 0.79; 95% Cl, 0.64-0.99). Conclusion: The majority of HIV-infected adults receiving medical care in the U.S. did not engage in sexual risk behaviours that have the potential to transmit HIV, and of the 12% whodid, approximately halfwere not virally suppressed. Persons who were virally suppressed were less likely than persons who were not suppressed to engage in sexual risk behaviours. JF - AIDS AU - Mattson, Christine L AU - Freedman, Mark AU - Fagan, Jennifer L AU - Frazier, Emma L AU - Beer, Linda AU - Huang, Ping AU - Valverde, Eduardo E AU - Johnson, Christopher AU - Sanders, Catherine AU - McNaghten, A D AD - Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention (CDC), CMattson@cdc.gov Y1 - 2014/05/15/ PY - 2014 DA - 2014 May 15 SP - 1203 EP - 1211 PB - Lippincott Williams & Wilkins, Inc, 530 Walnut Street Philadelphia PA 19106-3621 United States VL - 28 IS - 8 SN - 0269-9370, 0269-9370 KW - Health & Safety Science Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - antiretroviral therapy KW - HIV-infected persons KW - sexual behaviour KW - unsafe sex KW - viral load KW - USA KW - Acquired immune deficiency syndrome KW - anal sex KW - Data processing KW - Human immunodeficiency virus KW - medical records KW - Vagina KW - Anal sex KW - Sexual behavior KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1765980340?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS&rft.atitle=Sexual+risk+behaviour+and+viral+suppression+among+HIV-infected+adults+receiving+medical+care+in+the+United+States&rft.au=Mattson%2C+Christine+L%3BFreedman%2C+Mark%3BFagan%2C+Jennifer+L%3BFrazier%2C+Emma+L%3BBeer%2C+Linda%3BHuang%2C+Ping%3BValverde%2C+Eduardo+E%3BJohnson%2C+Christopher%3BSanders%2C+Catherine%3BMcNaghten%2C+A+D&rft.aulast=Mattson&rft.aufirst=Christine&rft.date=2014-05-15&rft.volume=28&rft.issue=8&rft.spage=1203&rft.isbn=&rft.btitle=&rft.title=AIDS&rft.issn=02699370&rft_id=info:doi/10.1097%2FQAD.0000000000000273 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Data processing; anal sex; medical records; Vagina; Sexual behavior; Acquired immune deficiency syndrome; Human immunodeficiency virus; Anal sex; USA DO - http://dx.doi.org/10.1097/QAD.0000000000000273 ER - TY - JOUR T1 - Possible Rabies Exposures in Peace Corps Volunteers, 2011 AN - 1647023044; 21184031 AB - We surveyed Peace Corps Medical Officers (PCMOs) to determine the frequency of and responses to possible rabies exposures of U.S. Peace Corps volunteers (PCVs). Surveys were sent to 56 PCMOs serving in countries with moderate or high rabies vaccine recommendations from the U.S. Centers for Disease Control and Prevention (CDC), of which 38 (68%) responded. Thirty-seven PCMOs reported that, of 4,982 PCVs, 140 (3%) experienced possible rabies exposures. Of these, 125 (89%) had previously received rabies vaccination, 129 (92%) presented with adequately cleansed wounds, and 106 (76%) were deemed to require and were given post-exposure prophylaxis (PEP). Of 35 respondents, 30 (86%) reported that rabies vaccine was always accessible to PCVs in their country within 24 hours. Overall, the Peace Corps is successful at preventing and treating possible rabies exposures. However, this study identified a few gaps in policy implementation. The Peace Corps should continue and strengthen efforts to provide education, preexposure vaccination, and PEP to PCVs. JF - American Journal of Tropical Medicine and Hygiene AU - Harvey, Kira AU - Jentes, Emily S AU - Charles, Myrna AU - Johnson, Katherine J AU - Petersen, Brett AU - Lamias, Mark J AU - Blanton, Jesse D AU - Sotir, Mark J AU - Brunette, Gary W AD - Division of Global Migration and Quarantine, Centers for Disease Control and Prevention, 1600 Clifton Road, MS E-03, Atlanta, GA; Office of Medical Services, Peace Corps, Washington, District of Columbia; Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, Georgia; Office of Informatics, Centers for Disease Control and Prevention, Atlanta, Georgia, jii3@cdc.gov Y1 - 2014/05// PY - 2014 DA - May 2014 SP - 902 EP - 907 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 90 IS - 5 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Education KW - Prevention KW - Rabies KW - Prophylaxis KW - Disease control KW - Vaccines KW - Vaccination KW - Wounds KW - K 03400:Human Diseases KW - J 02350:Immunology KW - V 22400:Human Diseases KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1647023044?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Possible+Rabies+Exposures+in+Peace+Corps+Volunteers%2C+2011&rft.au=Harvey%2C+Kira%3BJentes%2C+Emily+S%3BCharles%2C+Myrna%3BJohnson%2C+Katherine+J%3BPetersen%2C+Brett%3BLamias%2C+Mark+J%3BBlanton%2C+Jesse+D%3BSotir%2C+Mark+J%3BBrunette%2C+Gary+W&rft.aulast=Harvey&rft.aufirst=Kira&rft.date=2014-05-01&rft.volume=90&rft.issue=5&rft.spage=902&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.13-0521 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Rabies; Disease control; Prophylaxis; Vaccines; Vaccination; Wounds; Prevention; Education DO - http://dx.doi.org/10.4269/ajtmh.13-0521 ER - TY - JOUR T1 - Inconclusive Reverse Transcription-PCR Assay Comparison for Dengue Virus Detection and Serotyping AN - 1611623378; 19798249 JF - Journal of Clinical Microbiology AU - Munoz-Jordan, Jorge L AU - Santiago, Gilberto A Y1 - 2014/05// PY - 2014 DA - May 2014 SP - 1800 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 52 IS - 5 SN - 0095-1137, 0095-1137 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources KW - Dengue virus KW - Microbiology KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1611623378?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Inconclusive+Reverse+Transcription-PCR+Assay+Comparison+for+Dengue+Virus+Detection+and+Serotyping&rft.au=Munoz-Jordan%2C+Jorge+L%3BSantiago%2C+Gilberto+A&rft.aulast=Munoz-Jordan&rft.aufirst=Jorge&rft.date=2014-05-01&rft.volume=52&rft.issue=5&rft.spage=1800&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.03420-13 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-10-01 N1 - Number of references - 10 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Microbiology; Dengue virus DO - http://dx.doi.org/10.1128/JCM.03420-13 ER - TY - JOUR T1 - Assessment of Etest as an Alternative to Agar Dilution for Antimicrobial Susceptibility Testing of Neisseria gonorrhoeae AN - 1534836685; 19798209 AB - We studied whether the Etest can be used as an alternative to agar dilution to determine antimicrobial susceptibilities of ceftriaxone, cefixime, and cefpodoxime in Neisseria gonorrhoeae surveillance. One hundred fifteen clinical and laboratory isolates of N. gonorrhoeae were tested following the Clinical Laboratory Improvement Amendments (CLIA)-approved CLSI standard agar dilution method and, separately, by the Etest according to the manufacturer's recommendations. The MICs were determined and compared. Ten laboratory-generated mutants were used to simulate substantially nonsusceptible specimens. The Etest and agar dilution methods were well correlated. Statistical tests produced regression R2 values of 88%, 82%, and 85% and Pearson correlation coefficients of 92%, 91%, and 92% for ceftriaxone, cefixime, and cefpodoxime, respectively. When paired comparisons were made, the two tests were 88.7%, 80%, and 87% within 1 log2 dilution from each other for ceftriaxone, cefixime, and cefpodoxime, respectively. The within-2-log2 agreements were 99.1%, 98.3%, and 94.8% for ceftriaxone, cefixime, and cefpodoxime, respectively. Notwithstanding the good correlations and the within-2-log2 general agreement, the Etest results produced slightly lower MICs than the agar dilution results. In conclusion, we found that the Etest can be effectively used as an alternative to agar dilution testing to determine the susceptibility of N. gonorrhoeae to ceftriaxone, cefixime, and cefpodoxime, although we recommend further research into extremely resistant isolates. For isolates within the typical range of clinical MICs, reexamination of the Etest interpretation of susceptible and nonsusceptible categories would likely allow for successful transition from agar dilution to the Etest. JF - Journal of Clinical Microbiology AU - Liu, Hsi AU - Taylor, Thomas H, Jr AU - Pettus, Kevin AU - Trees, David AD - Division of Sexually Transmitted Disease Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, hcl6@cdc.gov. Y1 - 2014/05// PY - 2014 DA - May 2014 SP - 1435 EP - 1440 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 52 IS - 5 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology KW - Agar KW - Cefixime KW - Statistical analysis KW - Ceftriaxone KW - Cefpodoxime KW - Minimum inhibitory concentration KW - Neisseria gonorrhoeae KW - Antimicrobial agents KW - A 01340:Antibiotics & Antimicrobials KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1534836685?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Assessment+of+Etest+as+an+Alternative+to+Agar+Dilution+for+Antimicrobial+Susceptibility+Testing+of+Neisseria+gonorrhoeae&rft.au=Liu%2C+Hsi%3BTaylor%2C+Thomas+H%2C+Jr%3BPettus%2C+Kevin%3BTrees%2C+David&rft.aulast=Liu&rft.aufirst=Hsi&rft.date=2014-05-01&rft.volume=52&rft.issue=5&rft.spage=1435&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.02131-13 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-06-01 N1 - Number of references - 21 N1 - Last updated - 2016-07-20 N1 - SubjectsTermNotLitGenreText - Agar; Cefixime; Statistical analysis; Ceftriaxone; Minimum inhibitory concentration; Cefpodoxime; Antimicrobial agents; Neisseria gonorrhoeae DO - http://dx.doi.org/10.1128/JCM.02131-13 ER - TY - JOUR T1 - Pharmacokinetic and Safety Analyses of Tenofovir and Tenofovir-Emtricitabine Vaginal Tablets in Pigtailed Macaques AN - 1524416426; 19798049 AB - Vaginal rapidly disintegrating tablets (RDTs) containing tenofovir (TFV) or TFV and emtricitabine (FTC) were evaluated for safety and pharmacokinetics in pigtailed macaques. Two separate animal groups (n = 4) received TFV (10 mg) or TFV-FTC (10 mg each) RDTs, administered near the cervix. A third group (n = 4) received 1 ml TFV gel. Blood plasma, vaginal tissue biopsy specimens, and vaginal fluids were collected before and after product application at 0, 0.5, 1, 4, and 24 h. A disintegration time of <30 min following vaginal application of the RDTs was noted, with negligible effects on local inflammatory cytokines, vaginal pH, and microflora. TFV pharmacokinetics were generally similar for both RDTs and gel, with peak median concentrations in vaginal tissues and vaginal secretions being on the order of 104 to 105 ng/g (147 to 571 mu M) and 106 ng/g (12 to 34 mM), respectively, at 1 to 4 h postdose. At 24 h, however, TFV vaginal tissue levels were more sustained after RDT dosing, with median TFV concentrations being approximately 1 log higher than those with gel dosing. FTC pharmacokinetics after combination RDT dosing were similar to those of TFV, with peak median vaginal tissue and fluid levels being on the order of 104 ng/g (374 mu M) and 106 ng/g (32 mM), respectively, at 1 h postdose with levels in fluid remaining high at 24 h. RDTs are a promising alternative vaginal dosage form, delivering TFV and/or FTC at levels that would be considered inhibitory to simian-human immunodeficiency virus in the macaque vaginal microenvironment over a 24-h period. JF - Antimicrobial Agents & Chemotherapy AU - Pereira, Lara E AU - Clark, Meredith R AU - Friend, David R AU - Garber, David A AU - McNicholl, Janet M AU - Hendry, R Michael AU - Doncel, Gustavo F AU - Smith, James M AD - LifeSource BioMedical LLC, Moffet Field, California, USA, ajo9@cdc.gov. Y1 - 2014/05// PY - 2014 DA - May 2014 SP - 2665 EP - 2674 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 58 IS - 5 SN - 0066-4804, 0066-4804 KW - Virology & AIDS Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Macaca KW - Secretions KW - Simian/human immunodeficiency virus KW - Tablets KW - Biopsy KW - tenofovir KW - Pharmacokinetics KW - Inflammation KW - Blood KW - Emtricitabine KW - Vagina KW - Microflora KW - Microenvironments KW - Cytokines KW - Cervix KW - pH effects KW - A 01340:Antibiotics & Antimicrobials KW - V 22340:Antiviral Agents UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1524416426?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Pharmacokinetic+and+Safety+Analyses+of+Tenofovir+and+Tenofovir-Emtricitabine+Vaginal+Tablets+in+Pigtailed+Macaques&rft.au=Pereira%2C+Lara+E%3BClark%2C+Meredith+R%3BFriend%2C+David+R%3BGarber%2C+David+A%3BMcNicholl%2C+Janet+M%3BHendry%2C+R+Michael%3BDoncel%2C+Gustavo+F%3BSmith%2C+James+M&rft.aulast=Pereira&rft.aufirst=Lara&rft.date=2014-05-01&rft.volume=58&rft.issue=5&rft.spage=2665&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.02336-13 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-05-01 N1 - Number of references - 38 N1 - Last updated - 2014-10-02 N1 - SubjectsTermNotLitGenreText - Secretions; Tablets; tenofovir; Biopsy; Pharmacokinetics; Inflammation; Blood; Emtricitabine; Vagina; Microflora; Cytokines; Microenvironments; Cervix; pH effects; Macaca; Simian/human immunodeficiency virus DO - http://dx.doi.org/10.1128/AAC.02336-13 ER - TY - JOUR T1 - Clostridium botulinum Strains Producing BoNT/F4 or BoNT/F5 AN - 1524409755; 19802286 AB - Botulinum neurotoxin type F (BoNT/F) may be produced by Clostridium botulinum alone or in combination with another toxin type such as BoNT/A or BoNT/B. Type F neurotoxin gene sequences have been further classified into seven toxin subtypes. Recently, the genome sequence of one strain of C. botulinum (Af84) was shown to contain three neurotoxin genes (bont/F4, bont/F5, and bont/A2). In this study, eight strains containing bont/F4 and seven strains containing bont/F5 were examined. Culture supernatants produced by these strains were incubated with BoNT/F-specific peptide substrates. Cleavage products of these peptides were subjected to mass spectral analysis, allowing detection of the BoNT/F subtypes present in the culture supernatants. PCR analysis demonstrated that a plasmid-specific marker (PL-6) was observed only among strains containing bont/F5. Among these strains, Southern hybridization revealed the presence of an approximately 242-kb plasmid harboring bont/F5. Genome sequencing of four of these strains revealed that the genomic backgrounds of strains harboring either bont/F4 or bont/F5 are diverse. None of the strains analyzed in this study were shown to produce BoNT/F4 and BoNT/F5 simultaneously, suggesting that strain Af84 is unusual. Finally, these data support a role for the mobility of a bont/F5-carrying plasmid among strains of diverse genomic backgrounds. JF - Applied and Environmental Microbiology AU - Raphael, Brian H AU - Bradshaw, Marite AU - Kalb, Suzanne R AU - Joseph, Lavin A AU - Luquez, Carolina AU - Barr, John R AU - Johnson, Eric A AU - Maslanka, Susan E AD - Centers for Disease Control and Prevention, Atlanta, Georgia, USA, BRaphael@cdc.gov. Y1 - 2014/05// PY - 2014 DA - May 2014 SP - 3250 EP - 3257 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 80 IS - 10 SN - 0099-2240, 0099-2240 KW - Toxicology Abstracts; Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Genomes KW - Data processing KW - Mobility KW - Nucleotide sequence KW - Polymerase chain reaction KW - Clostridium botulinum KW - genomics KW - Botulinum toxin KW - Plasmids KW - Neurotoxins KW - J 02310:Genetics & Taxonomy KW - X 24310:Pharmaceuticals KW - A 01300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1524409755?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Clostridium+botulinum+Strains+Producing+BoNT%2FF4+or+BoNT%2FF5&rft.au=Raphael%2C+Brian+H%3BBradshaw%2C+Marite%3BKalb%2C+Suzanne+R%3BJoseph%2C+Lavin+A%3BLuquez%2C+Carolina%3BBarr%2C+John+R%3BJohnson%2C+Eric+A%3BMaslanka%2C+Susan+E&rft.aulast=Raphael&rft.aufirst=Brian&rft.date=2014-05-01&rft.volume=80&rft.issue=10&rft.spage=3250&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/10.1128%2FAEM.00284-14 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-05-01 N1 - Number of references - 16 N1 - Last updated - 2014-06-26 N1 - SubjectsTermNotLitGenreText - Genomes; Data processing; Mobility; Nucleotide sequence; Polymerase chain reaction; Botulinum toxin; genomics; Neurotoxins; Plasmids; Clostridium botulinum DO - http://dx.doi.org/10.1128/AEM.00284-14 ER - TY - JOUR T1 - Structural Stability of Influenza A(H1N1)pdm09 Virus Hemagglutinins AN - 1520387579; 19678855 AB - The noncovalent interactions that mediate trimerization of the influenza hemagglutinin (HA) are important determinants of its biological activities. Recent studies have demonstrated that mutations in the HA trimer interface affect the thermal and pH sensitivities of HA, suggesting a possible impact on vaccine stability (). We used size exclusion chromatography analysis of recombinant HA ectodomain to compare the differences among recombinant trimeric HA proteins from early 2009 pandemic H1N1 viruses, which dissociate to monomers, with those of more recent virus HAs that can be expressed as trimers. We analyzed differences among the HA sequences and identified intermolecular interactions mediated by the residue at position 374 (HA0 numbering) of the HA2 subdomain as critical for HA trimer stability. Crystallographic analyses of HA from the recent H1N1 virus A/Washington/5/2011 highlight the structural basis for this observed phenotype. It remains to be seen whether more recent viruses with this mutation will yield more stable vaccines in the future. IMPORTANCE Hemagglutinins from the early 2009 H1N1 pandemic viruses are unable to maintain a trimeric complex when expressed in a recombinant system. However, HAs from 2010 and 2011 strains are more stable, and our work highlights that the improvement in stability can be attributed to an E374K substitution in the HA2 subunit of the stalk that emerged naturally in the circulating viruses. JF - Journal of Virology AU - Yang, Hua AU - Chang, Jessie C AU - Guo, Zhu AU - Carney, Paul J AU - Shore, David A AU - Donis, Ruben O AU - Cox, Nancy J AU - Villanueva, Julie M AU - Klimov, Alexander I AU - Stevens, James Y1 - 2014/05// PY - 2014 DA - May 2014 SP - 4828 EP - 4838 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 88 IS - 9 SN - 0022-538X, 0022-538X KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Sensitivity KW - Residues KW - Chromatography KW - Hemagglutinins KW - Viruses KW - Influenza KW - Monomers KW - USA, Washington KW - pandemics KW - Proteins KW - Vaccines KW - Mutation KW - pH effects KW - pH KW - V 22350:Immunology KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1520387579?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Virology&rft.atitle=Structural+Stability+of+Influenza+A%28H1N1%29pdm09+Virus+Hemagglutinins&rft.au=Yang%2C+Hua%3BChang%2C+Jessie+C%3BGuo%2C+Zhu%3BCarney%2C+Paul+J%3BShore%2C+David+A%3BDonis%2C+Ruben+O%3BCox%2C+Nancy+J%3BVillanueva%2C+Julie+M%3BKlimov%2C+Alexander+I%3BStevens%2C+James&rft.aulast=Yang&rft.aufirst=Hua&rft.date=2014-05-01&rft.volume=88&rft.issue=9&rft.spage=4828&rft.isbn=&rft.btitle=&rft.title=Journal+of+Virology&rft.issn=0022538X&rft_id=info:doi/10.1128%2FJVI.02278-13 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-04-01 N1 - Number of references - 38 N1 - Last updated - 2014-08-07 N1 - SubjectsTermNotLitGenreText - Monomers; Influenza; pandemics; Hemagglutinins; Vaccines; pH effects; Mutation; Sensitivity; Residues; Chromatography; Viruses; Proteins; pH; USA, Washington DO - http://dx.doi.org/10.1128/JVI.02278-13 ER - TY - JOUR T1 - Clam-associated vibriosis, USA, 1988-2010 AN - 1516744060; 19544271 AB - Infections with Vibrio spp. have frequently been associated with consumption of bivalve molluscs, especially oysters, but illness associated with clams has also been well documented. We describe the 2312 domestically acquired foodborne Vibrio infections reported to the Cholera and Other Vibrio Illness Surveillance system from 1988 to 2010. Clams were associated with at least 4% (93 persons, 'only clams') and possibly as many as 24% (556 persons, 'any clams') of foodborne cases. Of those who consumed 'only clams', 77% of infections were caused by V. parahaemolyticus. Clam-associated illnesses were generally similar to those associated with other seafood consumption. Clams associated with these illnesses were most frequently harvested from the Atlantic coastal states and eaten raw. Our study describes the contribution of clams to the overall burden of foodborne vibriosis and indicates that a comprehensive programme to prevent foodborne vibriosis need to address the risks associated with clams. JF - Epidemiology and Infection AU - Slayton, R B AU - Newton, A E AU - Depaola, A AU - Jones, J L AU - Mahon, B E AD - Epidemic Intelligence Service Officer, Centers for Disease Control and Prevention, Atlanta, GA, USA, via3@cdc.gov Y1 - 2014/05// PY - 2014 DA - May 2014 SP - 1083 EP - 1088 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 142 IS - 5 SN - 0950-2688, 0950-2688 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; Oceanic Abstracts; Risk Abstracts KW - Marine KW - Coastal states KW - Pathogenic bacteria KW - Food KW - Bacterial diseases KW - Surveillance and enforcement KW - Bivalves KW - Infection KW - Bivalvia KW - Vibriosis KW - USA KW - Vibrio KW - Epidemiology KW - Oysters KW - Vibrio parahaemolyticus KW - Marine molluscs KW - Cholera KW - Seafood KW - J 02410:Animal Diseases KW - Q1 08484:Species interactions: parasites and diseases KW - O 1080:Multi-disciplinary Studies KW - R2 23060:Medical and environmental health KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1516744060?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Clam-associated+vibriosis%2C+USA%2C+1988-2010&rft.au=Slayton%2C+R+B%3BNewton%2C+A+E%3BDepaola%2C+A%3BJones%2C+J+L%3BMahon%2C+B+E&rft.aulast=Slayton&rft.aufirst=R&rft.date=2014-05-01&rft.volume=142&rft.issue=5&rft.spage=1083&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268813001830 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-04-01 N1 - Number of references - 11 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Vibriosis; Coastal states; Epidemiology; Pathogenic bacteria; Bacterial diseases; Surveillance and enforcement; Marine molluscs; Seafood; Food; Cholera; Infection; Oysters; Bivalves; Bivalvia; Vibrio; Vibrio parahaemolyticus; USA; Marine DO - http://dx.doi.org/10.1017/S0950268813001830 ER - TY - JOUR T1 - Binational outbreak of Guillain-Barre syndrome associated with Campylobacter jejuni infection, Mexico and USA, 2011 AN - 1516740532; 19544282 AB - In June 2011, a cluster of suspected cases of Guillain-Barre syndrome (GBS), which can follow Campylobacter jejuni infection, was identified in San Luis Rio Colorado (SLRC), Sonora, Mexico and Yuma County, Arizona, USA. An outbreak investigation identified 26 patients (18 from Sonora, eight from Arizona) with onset of GBS 4 May-21 July 2011, exceeding the expected number of cases (n = 1-2). Twenty-one (81%) patients reported antecedent diarrhoea, and 61% of 18 patients tested were seropositive for C. jejuni IgM antibodies. In a case-control study matched on age group, sex, ethnicity, and neighbourhood of residence, all Arizona GBS patients travelled to SLRC during the exposure period vs. 45% of matched controls (matched odds ratio 8.1, 95% confidence interval 1.5- infinity ). Exposure information and an environmental assessment suggested that GBS cases resulted from a large outbreak of C. jejuni infection from inadequately disinfected tap water in SLRC. Binational collaboration was essential in investigating this cross-border GBS outbreak, the first in mainland North America since 1976. JF - Epidemiology and Infection AU - Jackson, B R AU - ZEGARRA, JALOMAA AU - Lopez-Gatell, H AU - SEJVAR, J AU - Arzate, F AU - Waterman, S AU - NUNEZ, ASANCHEZ AU - LoPEZ, B AU - Weiss, J AU - CRUZ, RQUINTERO AU - MURRIETA, DYLOPEZ AU - Luna-Gierke, R AU - Heiman, K AU - Vieira, A R AU - Fitzgerald, C AU - Kwan, P AU - Zarate-Bermudez, M AU - Talkington, D AU - Hill, V R AU - Mahon, B AD - Centers for Disease Control and Prevention, Atlanta, GA, USA, brjackson1@cdc.gov Y1 - 2014/05// PY - 2014 DA - May 2014 SP - 1089 EP - 1099 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 142 IS - 5 SN - 0950-2688, 0950-2688 KW - Microbiology Abstracts B: Bacteriology; Environment Abstracts; Health & Safety Science Abstracts KW - Disinfection KW - Age KW - Diarrhea KW - Environmental assessment KW - USA, Arizona, Yuma KW - Infection KW - Mexico KW - Guillain-Barre syndrome KW - Mexico, Sonora KW - Campylobacter jejuni KW - USA, Arizona KW - Outbreaks KW - Drinking water KW - Immunoglobulin M KW - Ethnic groups KW - Sex KW - J 02400:Human Diseases KW - H 12000:Epidemiology and Public Health KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1516740532?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Binational+outbreak+of+Guillain-Barre+syndrome+associated+with+Campylobacter+jejuni+infection%2C+Mexico+and+USA%2C+2011&rft.au=Jackson%2C+B+R%3BZEGARRA%2C+JALOMAA%3BLopez-Gatell%2C+H%3BSEJVAR%2C+J%3BArzate%2C+F%3BWaterman%2C+S%3BNUNEZ%2C+ASANCHEZ%3BLoPEZ%2C+B%3BWeiss%2C+J%3BCRUZ%2C+RQUINTERO%3BMURRIETA%2C+DYLOPEZ%3BLuna-Gierke%2C+R%3BHeiman%2C+K%3BVieira%2C+A+R%3BFitzgerald%2C+C%3BKwan%2C+P%3BZarate-Bermudez%2C+M%3BTalkington%2C+D%3BHill%2C+V+R%3BMahon%2C+B&rft.aulast=Jackson&rft.aufirst=B&rft.date=2014-05-01&rft.volume=142&rft.issue=5&rft.spage=1089&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268813001908 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-04-01 N1 - Number of references - 34 N1 - Last updated - 2016-03-30 N1 - SubjectsTermNotLitGenreText - Diarrhea; Guillain-Barre syndrome; Infection; Ethnic groups; Immunoglobulin M; Sex; Disinfection; Age; Environmental assessment; Outbreaks; Drinking water; Campylobacter jejuni; Mexico; Mexico, Sonora; USA, Arizona, Yuma; USA, Arizona DO - http://dx.doi.org/10.1017/S0950268813001908 ER - TY - JOUR T1 - Varicella zoster virus in American Samoa: seroprevalence and predictive value of varicella disease history in elementary and college students AN - 1516738833; 19544274 AB - The epidemiology of varicella is believed to differ between temperate and tropical countries. We conducted a varicella seroprevalence study in elementary and college students in the US territory of American Samoa before introduction of a routine varicella vaccination programme. Sera from 515 elementary and 208 college students were tested for the presence of varicella-zoster virus (VZV) IgG antibodies. VZV seroprevalence increased with age from 76.0% in the 4-6 years group to 97.7% in those aged 23 years. Reported history of varicella disease for elementary students was significantly associated with VZV seropositivity. The positive and negative predictive values of varicella disease history were 93.4% and 36.4%, respectively, in elementary students and 97.6% and 3.0%, respectively, in college students. VZV seroprevalence in this Pacific island appears to be similar to that in temperate countries and suggests endemic VZV circulation. JF - Epidemiology and Infection AU - MAHAMUD, A AU - Leung, J AU - MASUNU-FALEAFAGA, Y AU - TESHALE, E AU - Williams, R AU - Dulski, T AU - Thieme, M AU - Garcia, P AU - Schmid, D S AU - Bialek AD - National Center for Immunization and Respiratory Diseases, Centers for Diseases Control and Prevention, Atlanta, GA, USA, JLeung@cdc.gov Y1 - 2014/05// PY - 2014 DA - May 2014 SP - 1002 EP - 1007 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 142 IS - 5 SN - 0950-2688, 0950-2688 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - ISE, Pacific, American Samoa KW - Historical account KW - Age KW - Territory KW - Vaccination KW - Colleges and universities KW - I, Central Pacific, Pacific Ocean Is. KW - Islands KW - Epidemiology KW - Varicella-zoster virus KW - Immunoglobulin G KW - Vaccines KW - Varicella KW - H 12000:Epidemiology and Public Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1516738833?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Varicella+zoster+virus+in+American+Samoa%3A+seroprevalence+and+predictive+value+of+varicella+disease+history+in+elementary+and+college+students&rft.au=MAHAMUD%2C+A%3BLeung%2C+J%3BMASUNU-FALEAFAGA%2C+Y%3BTESHALE%2C+E%3BWilliams%2C+R%3BDulski%2C+T%3BThieme%2C+M%3BGarcia%2C+P%3BSchmid%2C+D+S%3BBialek&rft.aulast=MAHAMUD&rft.aufirst=A&rft.date=2014-05-01&rft.volume=142&rft.issue=5&rft.spage=1002&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS095026881300174X LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-04-01 N1 - Number of references - 20 N1 - Last updated - 2014-06-26 N1 - SubjectsTermNotLitGenreText - Age; Islands; Epidemiology; Immunoglobulin G; Territory; Vaccination; Varicella; Historical account; Vaccines; Colleges and universities; Varicella-zoster virus; ISE, Pacific, American Samoa; I, Central Pacific, Pacific Ocean Is. DO - http://dx.doi.org/10.1017/S095026881300174X ER - TY - JOUR T1 - Multilevel Regression and Poststratification for Small-Area Estimation of Population Health Outcomes: A Case Study of Chronic Obstructive Pulmonary Disease Prevalence Using the Behavioral Risk Factor Surveillance System AN - 1516742294; 19545028 AB - A variety of small-area statistical models have been developed for health surveys, but none are sufficiently flexible to generate small-area estimates (SAEs) to meet data needs at different geographic levels. We developed a multilevel logistic model with both state- and nested county-level random effects for chronic obstructive pulmonary disease (COPD) using 2011 data from the Behavioral Risk Factor Surveillance System. We applied poststratification with the (decennial) US Census 2010 counts of census-block population to generate census-block-level SAEs of COPD prevalence which could be conveniently aggregated to all other census geographic units, such as census tracts, counties, and congressional districts. The model-based SAEs and direct survey estimates of COPD prevalence were quite consistent at both the county and state levels. The Pearson correlation coefficient was 0.99 at the state level and ranged from 0.88 to 0.95 at the county level. Our extended multilevel regression modeling and poststratification approach could be adapted for other geocoded national health surveys to generate reliable SAEs for population health outcomes at all administrative and legislative geographic levels of interest in a scalable framework. JF - American Journal of Epidemiology AU - Zhang, Xingyou AU - Holt, James B AU - Lu, Hua AU - Wheaton, Anne G AU - Ford, Earl S AU - Greenlund, Kurt J AU - Croft, Janet B AD - Correspondence to Dr. Xingyou Zhang, Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway, Mailstop F78, Atlanta, GA 30341., gyx8@cdc.gov Y1 - 2014/04/15/ PY - 2014 DA - 2014 Apr 15 SP - 1025 EP - 1033 PB - Oxford University Press, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 179 IS - 8 SN - 0002-9262, 0002-9262 KW - Toxicology Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - Behavioral Risk Factor Surveillance System KW - chronic obstructive pulmonary disease KW - multilevel regression and poststratification KW - population health outcomes KW - small-area estimation KW - Data processing KW - Mathematical models KW - Statistical analysis KW - Chronic obstructive pulmonary disease KW - Models KW - Case studies KW - Risk factors KW - Census KW - Legislation KW - R2 23060:Medical and environmental health KW - H 12000:Epidemiology and Public Health KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1516742294?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Epidemiology&rft.atitle=Multilevel+Regression+and+Poststratification+for+Small-Area+Estimation+of+Population+Health+Outcomes%3A+A+Case+Study+of+Chronic+Obstructive+Pulmonary+Disease+Prevalence+Using+the+Behavioral+Risk+Factor+Surveillance+System&rft.au=Zhang%2C+Xingyou%3BHolt%2C+James+B%3BLu%2C+Hua%3BWheaton%2C+Anne+G%3BFord%2C+Earl+S%3BGreenlund%2C+Kurt+J%3BCroft%2C+Janet+B&rft.aulast=Zhang&rft.aufirst=Xingyou&rft.date=2014-04-15&rft.volume=179&rft.issue=8&rft.spage=1025&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Epidemiology&rft.issn=00029262&rft_id=info:doi/10.1093%2Faje%2Fkwu018 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-04-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Mathematical models; Data processing; Risk factors; Statistical analysis; Census; Models; Chronic obstructive pulmonary disease; Case studies; Legislation DO - http://dx.doi.org/10.1093/aje/kwu018 ER - TY - JOUR T1 - Encephalitis-Associated Hospitalizations among American Indians and Alaska Natives AN - 1717496250; PQ0002006821 AB - Encephalitis produces considerable morbidity in the United States, but morbidity rates among American Indian/Alaska Native (Al/AN) people have not been described. Hospitalization records listing an encephalitis diagnosis were analyzed by using Indian Health Service direct/contract inpatient data. For 1998-2010, there were 436 encephalitis-associated hospitalizations among Al/AN people, an average annual age-adjusted hospitalization rate of 3.1/100,000 population. The rate for infants (11.9) was more than double that for any other age group. Death occurred for 4.1% of hospitalizations. Consistent with reports for the general U.S. population, the rate was high among infants and most (53.9%) hospitalizations were of unexplained etiology. The average annual rate during the study period appeared lower than for the general U.S. population, due particularly to lower rates in the elderly. Future community-based surveillance and mortality studies are needed to confirm these findings and examine reasons underlying the low rates of encephalitis in AI/AN people. JF - American Journal of Tropical Medicine and Hygiene AU - Mehal, Jason M AU - Holman, Robert C AU - Vora, Neil M AU - Blanton, Jesse AU - Gordon, Paul H AU - Cheek, James E AD - Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, and Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia; Public Health Program, Department of Family and Community Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico; Northern Navajo Medical Center, Indian Health Service, Shiprock, New Mexico, jmehal@cdc.gov Y1 - 2014/04// PY - 2014 DA - April 2014 SP - 755 EP - 759 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 90 IS - 4 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; CSA Neurosciences Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Mortality KW - Etiology KW - Age KW - Data processing KW - Contracts KW - Surveillance and enforcement KW - INE, USA, Alaska KW - Encephalitis KW - Morbidity KW - Aetiology KW - Population genetics KW - Geriatrics KW - Age groups KW - Hygiene KW - Mortality causes KW - Infants KW - K 03400:Human Diseases KW - Q5 08504:Effects on organisms KW - J 02400:Human Diseases KW - Q1 08604:Stock assessment and management KW - N3 11150:General and miscellaneous topics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1717496250?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Encephalitis-Associated+Hospitalizations+among+American+Indians+and+Alaska+Natives&rft.au=Mehal%2C+Jason+M%3BHolman%2C+Robert+C%3BVora%2C+Neil+M%3BBlanton%2C+Jesse%3BGordon%2C+Paul+H%3BCheek%2C+James+E&rft.aulast=Mehal&rft.aufirst=Jason&rft.date=2014-04-01&rft.volume=90&rft.issue=4&rft.spage=755&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.13-0420 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-09-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Population genetics; Contracts; Surveillance and enforcement; Age groups; Hygiene; Aetiology; Mortality causes; Mortality; Age; Etiology; Data processing; Geriatrics; Morbidity; Encephalitis; Infants; INE, USA, Alaska DO - http://dx.doi.org/10.4269/ajtmh.13-0420 ER - TY - JOUR T1 - Longitudinal Evaluation of Enteric Protozoa in Haitian Children by Stool Exam and Multiplex Serologic Assay AN - 1717493739; PQ0002006805 AB - Haitian children were monitored longitudinally in a filariasis study. Included were stool samples examined for Giardia intestinalis and Entamoeba histolytica cysts, and serum specimens analyzed for immunoglobulin G (IgG) responses to eight recombinant antigens from G. intestinalis (variant-specific surface protein [VSP1-VSP5]), E. histolytica (lectin adhesion molecule [LecA]), and Cryptosporidium parvum (17- and 27-kDa) using a multiplex bead assay. The IgG responses to VSP antigens peaked at 2 years of age and then diminished and were significantly lower (P 4.5 years than in children < 4.5 years. The IgG responses to Cryptosporidium tended to increase with age. The IgG responses to LecA and VSP antigens and the prevalence of stools positive for cysts were significantly higher (P < 0.037 and P < 0.035, respectively) in the rainy season than in the dry season. The multiplex bead assay provides a powerful tool for analyzing serologic responses to multiple pathogens. JF - American Journal of Tropical Medicine and Hygiene AU - Moss, Delynn M AU - Priest, Jeffrey W AU - Hamlin, Kathy AU - Derado, Gordana AU - Herbein, Joel AU - Petri, William A, Jr AU - Lammie, Patrick J AD - Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Division of Parasitic Diseases and Malaria, National Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia; Departments of Medicine, Microbiology, and Pathology, University of Virginia, and TECHLAB, Inc., Blacksburg, Virginia; Centers for Disease Control and Prevention, Division of Foodborne, Waterborne, and Environmental Diseases, 1600 Clifton Rd., Atlanta, GA 30329, dmm3@cdc.gov Y1 - 2014/04// PY - 2014 DA - April 2014 SP - 653 EP - 660 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 90 IS - 4 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts C: Algology, Mycology & Protozoology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Age KW - Entamoeba histolytica KW - variant-specific surface protein KW - Filariasis KW - Giardia intestinalis KW - Lectins KW - Pathogens KW - Children KW - Cysts KW - Adhesion KW - Cryptosporidium parvum KW - Recombinants KW - Antigens KW - Rainy season KW - Protozoa KW - Intestines KW - Immunoglobulin G KW - Feces KW - Hygiene KW - Dry season KW - Q1 08424:Age and growth KW - K 03400:Human Diseases KW - J 02350:Immunology KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1717493739?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Longitudinal+Evaluation+of+Enteric+Protozoa+in+Haitian+Children+by+Stool+Exam+and+Multiplex+Serologic+Assay&rft.au=Moss%2C+Delynn+M%3BPriest%2C+Jeffrey+W%3BHamlin%2C+Kathy%3BDerado%2C+Gordana%3BHerbein%2C+Joel%3BPetri%2C+William+A%2C+Jr%3BLammie%2C+Patrick+J&rft.aulast=Moss&rft.aufirst=Delynn&rft.date=2014-04-01&rft.volume=90&rft.issue=4&rft.spage=653&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.13-0545 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-09-01 N1 - Last updated - 2016-02-04 N1 - SubjectsTermNotLitGenreText - Recombinants; Rainy season; Antigens; Intestines; Pathogens; Dry season; Hygiene; Cysts; Adhesion; Age; Protozoa; variant-specific surface protein; Filariasis; Immunoglobulin G; Lectins; Feces; Children; Entamoeba histolytica; Giardia intestinalis; Cryptosporidium parvum DO - http://dx.doi.org/10.4269/ajtmh.13-0545 ER - TY - JOUR T1 - Correlates of HIV Infection Among African American Women from 20 Cities in the United States AN - 1680150500; 201502953 AB - Little research has been conducted to investigate multiple levels of HIV risk-individual risk factors, sex partner characteristics, and socioeconomic factors-among African American women, who, in 2010, comprised 64 % of the estimated 9,500 new infections in women. Respondent-driven sampling was used to recruit and interview women in 20 cities with high AIDS prevalence in the United States through the National HIV Behavioral Surveillance System. We assessed individual risk factors, sex partner characteristics, and socioeconomic characteristics associated with being HIV-positive but unaware of the infection among African American women. Among 3,868 women with no previous diagnosis of HIV, 68 % had high school education or more and 84 % lived at or below the poverty line. In multivariable analysis, women who were 35 years or older, homeless, received Medicaid, whose last sex partner ever used crack cocaine or was an exchange sex partner were more likely to be HIV-positive-unaware. Developing and implementing strategies that address socioeconomic factors, such as homelessness and living in poverty, as well as individual risk factors, can help to maximize the effectiveness of the public health response to the HIV epidemic. Adapted from the source document. JF - AIDS and Behavior AU - Ivy, Wade AU - Miles, Isa AU - Le, Binh AU - Paz-Bailey, Gabriela AD - Behavioral and Clinical Surveillance Branch, Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Rd. NE, MS-E46, Atlanta, GA, 30333, USA Y1 - 2014/04// PY - 2014 DA - April 2014 SP - 266 EP - 275 PB - Springer, Dordrecht, The Netherlands VL - 18 IS - 3 SN - 1090-7165, 1090-7165 KW - Cities KW - Sexual Behavior KW - Black Americans KW - Public Health KW - Poverty KW - Acquired Immune Deficiency Syndrome KW - Females KW - Surveillance KW - Homelessness KW - article KW - 6126: acquired immune deficiency syndrome (AIDS) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1680150500?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocialservices&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Correlates+of+HIV+Infection+Among+African+American+Women+from+20+Cities+in+the+United+States&rft.au=Ivy%2C+Wade%3BMiles%2C+Isa%3BLe%2C+Binh%3BPaz-Bailey%2C+Gabriela&rft.aulast=Ivy&rft.aufirst=Wade&rft.date=2014-04-01&rft.volume=18&rft.issue=3&rft.spage=266&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-013-0614-x LA - English DB - Social Services Abstracts N1 - Date revised - 2015-05-01 N1 - Last updated - 2016-09-28 N1 - CODEN - AIBEFC N1 - SubjectsTermNotLitGenreText - Females; Acquired Immune Deficiency Syndrome; Sexual Behavior; Black Americans; Homelessness; Cities; Poverty; Surveillance; Public Health DO - http://dx.doi.org/10.1007/s10461-013-0614-x ER - TY - JOUR T1 - Prevalence of HIV Infection and Risk Behaviors Among Younger and Older Injecting Drug Users in the United States, 2009 AN - 1680150443; 201502843 AB - This study compared HIV sero-prevalence and risk behaviors between younger and older injecting drug users (IDUs). IDUs aged >=18 years were interviewed for the 2009 National HIV Behavioral Surveillance System. Using GEE regression, we assessed characteristics of younger (18-29 years) and older (>=30 years) IDUs, and factors associated with past 12-month receptive syringe sharing and unprotected sex (vaginal/anal). Of 10,090 participants, 10 % were younger. HIV sero-prevalence was lower among younger than older IDUs (4 vs. 10 %, p = 0.001). Younger IDUs were more likely (p <= 0.002) to be non-black race/ethnicity, report higher household income, homelessness, being arrested and to engage in receptive syringe sharing and unprotected sex. In multivariable models, age remained associated (p < 0.001) with receptive syringe sharing (aPR = 1.14, 95 % CI1.07-1.22) and unprotected sex (aPR = 1.10, 95 % CI1.06-1.14). Although younger IDUs had lower HIV prevalence, their behaviors place them at increased risk of HIV infection and could lead to a rapid spread in this susceptible population. Adapted from the source document. JF - AIDS and Behavior AU - Broz, Dita AU - Pham, Huong AU - Spiller, Michael AU - Wejnert, Cyprian AU - Le, Binh AU - Neaigus, Alan AU - Paz-Bailey, Gabriela AD - Behavioral and Clinical Surveillance Branch, Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, MS-E46, Atlanta, GA, 30333, USA dbroz@cdc.gov Y1 - 2014/04// PY - 2014 DA - April 2014 SP - 284 EP - 296 PB - Springer, Dordrecht, The Netherlands VL - 18 IS - 3 SN - 1090-7165, 1090-7165 KW - Risk KW - Ethnicity KW - Acquired Immune Deficiency Syndrome KW - Race KW - United States of America KW - Surveillance KW - Income KW - Drug Abuse KW - article KW - 6126: acquired immune deficiency syndrome (AIDS) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1680150443?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocialservices&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Prevalence+of+HIV+Infection+and+Risk+Behaviors+Among+Younger+and+Older+Injecting+Drug+Users+in+the+United+States%2C+2009&rft.au=Broz%2C+Dita%3BPham%2C+Huong%3BSpiller%2C+Michael%3BWejnert%2C+Cyprian%3BLe%2C+Binh%3BNeaigus%2C+Alan%3BPaz-Bailey%2C+Gabriela&rft.aulast=Broz&rft.aufirst=Dita&rft.date=2014-04-01&rft.volume=18&rft.issue=3&rft.spage=284&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-013-0660-4 LA - English DB - Social Services Abstracts N1 - Date revised - 2015-05-01 N1 - Last updated - 2016-09-28 N1 - CODEN - AIBEFC N1 - SubjectsTermNotLitGenreText - Acquired Immune Deficiency Syndrome; Risk; Drug Abuse; Race; United States of America; Income; Ethnicity; Surveillance DO - http://dx.doi.org/10.1007/s10461-013-0660-4 ER - TY - JOUR T1 - Serum Antibody Response to Matrix Protein 2 Following Natural Infection With 2009 Pandemic Influenza A(H1N1) Virus in Humans AN - 1618154353; 20800356 AB - Natural infection-induced humoral immunity to matrix protein 2 (M2) of influenza A viruses in humans is not fully understood. Evidence suggests that anti-M2 antibody responses following influenza A virus infection are weak and/or transient. We show that the seroprevalence of anti-M2 antibodies increased with age in 317 serum samples from healthy individuals in the United States in 2007-2008. Infection with 2009 pandemic H1N1 influenza A virus (A[H1N1]pdm09) elicited a recall serum antibody response to M2 protein of A(H1N1)pdm09 in 47% of the affected 118 individuals tested. Anti-M2 antibody responses were more robust among individuals with preexisting antibodies to M2 protein. Moreover, the antibodies induced as a result of infection with A(H1N1)pdm09 were cross-reactive with M2 protein of seasonal influenza A viruses. These results emphasize the need to further investigate the possible roles of anti-M2 antibodies in human influenza A virus infection. JF - Journal of Infectious Diseases AU - Zhong, Weimin AU - Reed, Carrie AU - Blair, Patrick J AU - Katz, Jacqueline M AU - Hancock, Kathy AD - Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA 30333, wzhong@cdc.gov Y1 - 2014/04/01/ PY - 2014 DA - 2014 Apr 01 SP - 986 EP - 994 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 209 IS - 7 SN - 0022-1899, 0022-1899 KW - Health & Safety Science Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - Influenza A virus KW - Matrix protein 2 KW - Antibody KW - Human KW - Age KW - Influenza A KW - Viruses KW - Antibody response KW - Infection KW - Influenza KW - matrix protein KW - Immunity (humoral) KW - USA KW - pandemics KW - Sulfur dioxide KW - Infectious diseases KW - Proteins KW - Seasonal variations KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - F 06910:Microorganisms & Parasites KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1618154353?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Serum+Antibody+Response+to+Matrix+Protein+2+Following+Natural+Infection+With+2009+Pandemic+Influenza+A%28H1N1%29+Virus+in+Humans&rft.au=Zhong%2C+Weimin%3BReed%2C+Carrie%3BBlair%2C+Patrick+J%3BKatz%2C+Jacqueline+M%3BHancock%2C+Kathy&rft.aulast=Zhong&rft.aufirst=Weimin&rft.date=2014-04-01&rft.volume=209&rft.issue=7&rft.spage=986&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjit811 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-10-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Immunity (humoral); matrix protein; Age; pandemics; Influenza A; Antibody response; Infection; Influenza; Sulfur dioxide; Infectious diseases; Viruses; Proteins; Seasonal variations; Influenza A virus; USA DO - http://dx.doi.org/10.1093/infdis/jit811 ER - TY - JOUR T1 - Development of a set of indicators to evaluate injury control research centers AN - 1560811858; 4596385 JF - Evaluation review AU - Runyan, Carol AU - Garrettson, Mariana AU - Yee, Sue AD - University of Colorado ; University of North Carolina ; National Center for Injury Prevention and Control Y1 - 2014/04// PY - 2014 DA - Apr 2014 SP - 133 EP - 159 VL - 38 IS - 2 SN - 0193-841X, 0193-841X KW - Sociology KW - Research centres KW - Measurement KW - Injuries KW - Educational research KW - Medical research KW - Methodology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1560811858?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Evaluation+review&rft.atitle=Development+of+a+set+of+indicators+to+evaluate+injury+control+research+centers&rft.au=Runyan%2C+Carol%3BGarrettson%2C+Mariana%3BYee%2C+Sue&rft.aulast=Runyan&rft.aufirst=Carol&rft.date=2014-04-01&rft.volume=38&rft.issue=2&rft.spage=133&rft.isbn=&rft.btitle=&rft.title=Evaluation+review&rft.issn=0193841X&rft_id=info:doi/10.1177%2F0193841X14529287 LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2014-09-08 N1 - Last updated - 2014-09-09 N1 - SubjectsTermNotLitGenreText - 7854; 7994; 6555 6220; 10906 10902; 7886 10902; 4100 10902 DO - http://dx.doi.org/10.1177/0193841X14529287 ER - TY - JOUR T1 - Fortification of corn masa flour with folic acid in the United States: an overview of the evidence AN - 1524412547; 19747250 AB - Corn masa flour, used to make products such as corn tortillas, is a staple food for Hispanic populations residing in the United States, particularly among Mexican Americans and Central Americans. Research has indicated that Hispanic women in the United States continue to be at a higher risk of having a neural tube defect-affected pregnancy than women of other races/ethnicities, even after the introduction of folic acid fortification of cereal grain products labeled as "enriched." Corn masa flour has, therefore, been suggested as a potential food vehicle for folic acid in the United States. This paper explores the potential impact that folic acid fortification of corn masa flour could have on the Hispanic population in the United States. JF - Annals of the New York Academy of Sciences AU - Hamner, Heather C AU - Tinker, Sarah C AD - National Center on Birth Defects and Developmental Disabilities. Centers for Disease Control and Prevention Y1 - 2014/04// PY - 2014 DA - Apr 2014 SP - 8 EP - 14 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 1312 IS - 1 SN - 0077-8923, 0077-8923 KW - Risk Abstracts KW - Corn KW - Folic acid KW - Grains KW - Ethnic groups KW - Neural tube defects KW - Pregnancy KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1524412547?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annals+of+the+New+York+Academy+of+Sciences&rft.atitle=Fortification+of+corn+masa+flour+with+folic+acid+in+the+United+States%3A+an+overview+of+the+evidence&rft.au=Hamner%2C+Heather+C%3BTinker%2C+Sarah+C&rft.aulast=Hamner&rft.aufirst=Heather&rft.date=2014-04-01&rft.volume=1312&rft.issue=1&rft.spage=8&rft.isbn=&rft.btitle=&rft.title=Annals+of+the+New+York+Academy+of+Sciences&rft.issn=00778923&rft_id=info:doi/10.1111%2Fnyas.12325 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-05-01 N1 - Number of references - 28 N1 - Last updated - 2015-04-29 N1 - SubjectsTermNotLitGenreText - Corn; Grains; Folic acid; Neural tube defects; Ethnic groups; Pregnancy DO - http://dx.doi.org/10.1111/nyas.12325 ER - TY - JOUR T1 - Antiviral Susceptibility of Variant Influenza A(H3N2)v Viruses Isolated in the United States from 2011 to 2013 AN - 1520387988; 19634151 AB - Since 2011, outbreaks caused by influenza A(H3N2) variant [A(H3N2)v] viruses have become a public health concern in the United States. The A(H3N2)v viruses share the A(H1N1)pdm09 M gene containing the marker of M2 blocker resistance, S31N, but do not contain any known molecular markers associated with resistance to neuraminidase (NA) inhibitors (NAIs). Using a fluorescent NA inhibition (NI) assay, the susceptibilities of recovered A(H3N2)v viruses (n = 168) to FDA-approved (oseltamivir and zanamivir) and other (peramivir, laninamivir, and A-315675) NAIs were assessed. All A(H3N2)v viruses tested, with the exception of a single virus strain, A/Ohio/88/2012, isolated from an untreated patient, were susceptible to the NAIs tested. The A/Ohio/88/2012 virus contained two rare substitutions, S245N and S247P, in the NA and demonstrated reduced inhibition by oseltamivir (31-fold) and zanamivir (66-fold) in the NI assay. Using recombinant NA (recNA) proteins, S247P was shown to be responsible for the observed altered NAI susceptibility, in addition to an approximately 60% reduction in NA enzymatic activity. The S247P substitution has not been previously reported as a molecular marker of reduced susceptibility to the NAIs. Using cell culture assays, the investigational antiviral drugs nitazoxanide, favipiravir, and fludase were shown to inhibit the replication of A(H3N2)v viruses, including the virus with the S247P substitution in the NA. This report demonstrates the importance of continuous monitoring of susceptibility of zoonotic influenza viruses to available and investigational antiviral drugs. JF - Antimicrobial Agents & Chemotherapy AU - Sleeman, K AU - Mishin, V P AU - Guo, Z AU - Garten, R J AU - Balish, A AU - Fry, A M AU - Villanueva, J AU - Stevens, J AU - Gubareva, L V AD - Virology, Surveillance and Diagnosis Branch, Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, LGubareva@cdc.gov. Y1 - 2014/04// PY - 2014 DA - Apr 2014 SP - 2045 EP - 2051 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 58 IS - 4 SN - 0066-4804, 0066-4804 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Replication KW - Chemotherapy KW - Viruses KW - M gene KW - Cell culture KW - Zanamivir KW - Antimicrobial agents KW - Oseltamivir KW - Public health KW - Influenza KW - Antiviral agents KW - Proteins KW - Outbreaks KW - Exo- alpha -sialidase KW - Enzymatic activity KW - USA, Ohio KW - Drugs KW - A 01340:Antibiotics & Antimicrobials KW - V 22320:Replication KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1520387988?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Antiviral+Susceptibility+of+Variant+Influenza+A%28H3N2%29v+Viruses+Isolated+in+the+United+States+from+2011+to+2013&rft.au=Sleeman%2C+K%3BMishin%2C+V+P%3BGuo%2C+Z%3BGarten%2C+R+J%3BBalish%2C+A%3BFry%2C+A+M%3BVillanueva%2C+J%3BStevens%2C+J%3BGubareva%2C+L+V&rft.aulast=Sleeman&rft.aufirst=K&rft.date=2014-04-01&rft.volume=58&rft.issue=4&rft.spage=2045&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.02556-13 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-04-01 N1 - Number of references - 37 N1 - Last updated - 2015-09-30 N1 - SubjectsTermNotLitGenreText - Influenza; Antiviral agents; Replication; Cell culture; M gene; Enzymatic activity; Exo- alpha -sialidase; Zanamivir; Public health; Oseltamivir; Chemotherapy; Viruses; Proteins; Outbreaks; Drugs; Antimicrobial agents; USA, Ohio DO - http://dx.doi.org/10.1128/AAC.02556-13 ER - TY - JOUR T1 - Determination of 8 organic pollutants in drinking waters by ultra-high performance liquid chromatography tandem mass spectrometry with direct injection AN - 1832650857; 778748-18 AB - In 2011, new healthy standards for drinking water were implemented, which included 106 health indicators and related detection methods. In the national standard methods, microcystins and atrazine are detected by Liquid Chromatography with Ultraviolet Detector; acrylamide, bentazone and 2, 4-D are detected by Gas Chromatography with Electron Capture Detector, carbofuran and glyphosate are measured by Liquid Chromatography with Fluorescence Detector. All of these methods are cumbersome and have poor operability making them difficult to conduct on a daily basis. A method for the analysis of 8 organic pollutants (glyphosate, carbofuran, bentazone, atrazine, 2, 4-D, acrylamide, microcystin-RR and microcystin-LR) in drinking water, surface water and underground water was developed using Ultra Performance Liquid Chromatography with Tandem Mass Spectrometry (UPLC-MS-MS). After filtration by 0.22 mu m membrane, the water sample was injection directly into the equipment. Compared with recently reported methods, similar precision and accuracy were obtained and are presented in this paper. But shorter analysis time is needed and more target compounds are included. The result indicate that the LOQ of 8 compounds ranged from 0. 07 to 5 mu g/L, Meanwhile, the high correlation coefficients (r>0.993) of 8 compounds were obtained within the respective linear ranges. The average recoveries at low, intermediate and high spiked levels range from 94.2% to 103.7% with relative standard deviations (RSD, n = 6) of 1.1%-7.8%. This method is suitable for the identification and quantification of the aforementioned 8 compounds in drinking water with the advantages of simple pretreatment, good reliability and high sensitivity. JF - Yankuang Ceshi = Rock and Mineral Analysis AU - Yang, Lixin AU - Zhang, Jianbo AU - Lu, Yang AU - Liu, Yinping AU - Dong, Bin AU - Chang, Fengqi Y1 - 2014/03// PY - 2014 DA - March 2014 SP - 275 EP - 281 PB - Dizhi Chubanshe, Beijing VL - 33 IS - 2 SN - 0254-5357, 0254-5357 KW - methods KW - liquid chromatography KW - chromatography KW - chemical analysis KW - pollutants KW - herbicides KW - pollution KW - mass spectroscopy KW - drinking water KW - organic compounds KW - pesticides KW - water pollution KW - spectroscopy KW - geochemistry KW - 22:Environmental geology KW - 02A:General geochemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1832650857?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefinprocess&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Yankuang+Ceshi+%3D+Rock+and+Mineral+Analysis&rft.atitle=Determination+of+8+organic+pollutants+in+drinking+waters+by+ultra-high+performance+liquid+chromatography+tandem+mass+spectrometry+with+direct+injection&rft.au=Yang%2C+Lixin%3BZhang%2C+Jianbo%3BLu%2C+Yang%3BLiu%2C+Yinping%3BDong%2C+Bin%3BChang%2C+Fengqi&rft.aulast=Yang&rft.aufirst=Lixin&rft.date=2014-03-01&rft.volume=33&rft.issue=2&rft.spage=275&rft.isbn=&rft.btitle=&rft.title=Yankuang+Ceshi+%3D+Rock+and+Mineral+Analysis&rft.issn=02545357&rft_id=info:doi/ LA - Chinese DB - GeoRef N1 - Copyright - GeoRef in Process, Copyright 2017, American Geosciences Institute. After editing and indexing, this record will be added to Georef. N1 - Number of references - 19 N1 - Document feature - illus. incl. 3 tables N1 - Last updated - 2017-01-24 N1 - SubjectsTermNotLitGenreText - chemical analysis; chromatography; drinking water; geochemistry; herbicides; liquid chromatography; mass spectroscopy; methods; organic compounds; pesticides; pollutants; pollution; spectroscopy; water pollution ER - TY - JOUR T1 - Diagnostic dilemma: treatment outcomes of tuberculosis patients with inconsistent rifampicin susceptibility AN - 1540234892; 20039090 AB - OBJECTIVE: A retrospective clinical trial to evaluate treatment outcomes in adults with smear-positive tuberculosis (TB) and discordant rifampicin (RMP) resistance results. DESIGN: A total of 2156 smear-positive TB patients underwent both conventional and Genechip(R) drug susceptibility testing (DST) for RMP resistance. All 49 patients with discordant results treated with either a firstline or second-line regimen were analysed. RESULTS: Of 30 Type I cases (Genechip-resistant, conventional DST-susceptible) receiving the first-line regimen, 4 had a favourable outcome and 5 failed treatment. The 21 remaining Type I cases were treated with the second-line regimen, of whom 18 had a favourable outcome. Second-line regimen thus resulted in significantly more favourable outcomes than first-line treatment (P = 0.032). Among Type II cases (Genechip-susceptible, conventional DST-resistant), 13/19 received the first-line regimen, and 7 had a favourable outcome. The six Type II cases treated with the second-line regimen all had favourable outcomes. CONCLUSION: Patients with discordant RMP DST results who receive second-line regimens may have a better clinical response than those treated with the first-line regimen. Patients infected with fluoroquinolone-resistant Mycobacterium tuberculosis strains were observed to have a significantly higher treatment failure rate. JF - International Journal of Tuberculosis and Lung Disease AU - Pang, Y AU - Ruan, Y-Z AU - Zhao, J AU - Chen, C AU - Xu, C-H AU - Su, W AU - Huan, S-T AU - Li, R-Z AU - Zhao, Y-L AU - Chin, D P AU - Wang, L-X AD - National Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, lirenzhong@chinatb.org Y1 - 2014/03// PY - 2014 DA - Mar 2014 SP - 357 EP - 362 PB - International Union Against Tuberculosis and Lung Disease, 68 bvd Saint-Michel Paris 75006 France VL - 18 IS - 3 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology KW - tuberculosis KW - rifampicin KW - clinical outcome KW - Rifampin KW - Lung diseases KW - Tuberculosis KW - Drug development KW - Clinical trials KW - Mycobacterium tuberculosis KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1540234892?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Diagnostic+dilemma%3A+treatment+outcomes+of+tuberculosis+patients+with+inconsistent+rifampicin+susceptibility&rft.au=Pang%2C+Y%3BRuan%2C+Y-Z%3BZhao%2C+J%3BChen%2C+C%3BXu%2C+C-H%3BSu%2C+W%3BHuan%2C+S-T%3BLi%2C+R-Z%3BZhao%2C+Y-L%3BChin%2C+D+P%3BWang%2C+L-X&rft.aulast=Pang&rft.aufirst=Y&rft.date=2014-03-01&rft.volume=18&rft.issue=3&rft.spage=357&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/10.5588%2Fijtld.13.0459 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-06-01 N1 - Last updated - 2015-04-16 N1 - SubjectsTermNotLitGenreText - Rifampin; Lung diseases; Drug development; Tuberculosis; Clinical trials; Mycobacterium tuberculosis DO - http://dx.doi.org/10.5588/ijtld.13.0459 ER - TY - JOUR T1 - Fluoroquinolone Susceptibility Testing of Salmonella enterica: Detection of Acquired Resistance and Selection of Zone Diameter Breakpoints for Levofloxacin and Ofloxacin AN - 1520372979; 19446583 AB - Fluoroquinolones (e.g., ciprofloxacin) have become a mainstay for treating severe Salmonella infections in adults. Fluoroquinolone resistance in Salmonella is mostly due to mutations in the topoisomerase genes, but plasmid-mediated quinolone resistance (PMQR) mechanisms have also been described. In 2012, the Clinical and Laboratory Standards Institute (CLSI) revised the ciprofloxacin interpretive criteria (breakpoints) for disk diffusion and MIC test methods for Salmonella. In 2013, the CLSI published MIC breakpoints for Salmonella to levofloxacin and ofloxacin, but breakpoints for assigning disk diffusion results to susceptible (S), intermediate (I), and resistant (R) categories are still needed. In this study, the MICs and inhibition zone diameters for nalidixic acid, ciprofloxacin, levofloxacin, and ofloxacin were determined for 100 clinical isolates of nontyphi Salmonella with or without resistance mechanisms. We confirmed that the new levofloxacin MIC breakpoints resulted in the highest category agreement (94%) when plotted against the ciprofloxacin MICs and that the new ofloxacin MIC breakpoints resulted in 92% category agreement between ofloxacin and ciprofloxacin. By applying the new MIC breakpoints in the MIC zone scattergrams for levofloxacin and ofloxacin, the following disk diffusion breakpoints generated the least number of errors: greater than or equal to 28 mm (S), 19 to 27 mm (I), and less than or equal to 18 mm (R) for levofloxacin and greater than or equal to 25 mm (S), 16 to 24 mm (I), and less than or equal to 15 mm (R) for ofloxacin. Neither the levofloxacin nor the ofloxacin disk yielded good separation of isolates with and without resistance mechanisms. Further studies will be needed to develop a disk diffusion assay that efficiently detects all isolates with acquired resistance to fluoroquinolones. JF - Journal of Clinical Microbiology AU - Sjolund-Karlsson, Maria AU - Howie, Rebecca L AU - Crump, John A AU - Whichard, Jean M AD - Centers for Disease Control and Prevention, Atlanta, Georgia, USA, fwt4@cdc.gov. Y1 - 2014/03// PY - 2014 DA - Mar 2014 SP - 877 EP - 884 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 52 IS - 3 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Clinical isolates KW - Fluoroquinolones KW - Levofloxacin KW - Ofloxacin KW - Quinolones KW - Infection KW - Minimum inhibitory concentration KW - Breakpoints KW - Ciprofloxacin KW - Salmonella enterica KW - Nalidixic acid KW - Diffusion KW - Mutation KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1520372979?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Fluoroquinolone+Susceptibility+Testing+of+Salmonella+enterica%3A+Detection+of+Acquired+Resistance+and+Selection+of+Zone+Diameter+Breakpoints+for+Levofloxacin+and+Ofloxacin&rft.au=Sjolund-Karlsson%2C+Maria%3BHowie%2C+Rebecca+L%3BCrump%2C+John+A%3BWhichard%2C+Jean+M&rft.aulast=Sjolund-Karlsson&rft.aufirst=Maria&rft.date=2014-03-01&rft.volume=52&rft.issue=3&rft.spage=877&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.02679-13 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-04-01 N1 - Number of references - 32 N1 - Last updated - 2015-06-26 N1 - SubjectsTermNotLitGenreText - Clinical isolates; Ciprofloxacin; Breakpoints; Fluoroquinolones; Levofloxacin; Quinolones; Ofloxacin; Nalidixic acid; Diffusion; Infection; Mutation; Minimum inhibitory concentration; Salmonella enterica DO - http://dx.doi.org/10.1128/JCM.02679-13 ER - TY - JOUR T1 - Assessment of New Culture Method for Detection of Borrelia Species from Serum of Lyme Disease Patients AN - 1520371437; 19446569 AB - A novel method of culturing spirochetes from the serum of U.S. Lyme disease patients was recently reported by Sapi and colleagues to have 94% sensitivity and 100% specificity for Borrelia species as assessed by microscopy and DNA sequence analysis of the pyrG gene (E. Sapi, N. Pabbati, A. Datar, E. M. Davies, A. Rattelle, and B. A. Kuo, Int. J. Med. Sci. 10:362-376, 2013). The majority of the spirochetes described were related by pyrG sequences to species of Borrelia previously undetected in North American patients without a reported history of travel to Europe or Asia. To better understand these unexpected findings, we determined pyrG sequences of the laboratory reference strains used by the investigators for method development and testing of culture medium. Eighty percent (41/51) of the reported patient-derived pyrG sequences were identical to one of the laboratory strains, and an additional 12% (6/51) differed by only a single nucleotide across a 603-bp region of the pyrG gene. Thus, false positivity due to laboratory contamination of patient samples cannot be ruled out, and further validation of the proposed novel culture method is required. JF - Journal of Clinical Microbiology AU - Johnson, Barbara JB AU - Pilgard, Mark A AU - Russell, Theresa M Y1 - 2014/03// PY - 2014 DA - March 2014 SP - 721 EP - 724 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 52 IS - 3 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Travel KW - Spirochetes KW - Contamination KW - Nucleotide sequence KW - Microscopy KW - Borrelia KW - pyrG gene KW - Lyme disease KW - J 02300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1520371437?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Assessment+of+New+Culture+Method+for+Detection+of+Borrelia+Species+from+Serum+of+Lyme+Disease+Patients&rft.au=Johnson%2C+Barbara+JB%3BPilgard%2C+Mark+A%3BRussell%2C+Theresa+M&rft.aulast=Johnson&rft.aufirst=Barbara&rft.date=2014-03-01&rft.volume=52&rft.issue=3&rft.spage=721&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.01674-13 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-04-01 N1 - Number of references - 15 N1 - Last updated - 2016-07-20 N1 - SubjectsTermNotLitGenreText - Travel; Spirochetes; Contamination; Nucleotide sequence; Microscopy; Lyme disease; pyrG gene; Borrelia DO - http://dx.doi.org/10.1128/JCM.01674-13 ER - TY - JOUR T1 - Hepatitis A and enteric fever in Greece, 2004-2011: A cross-sectional analysis AN - 1516745641; 19515196 AB - Background In Greece the number of international travellers has increased significantly the past decade. Aim To study the impact of international travels on the epidemiology of hepatitis A and enteric fever in Greece. Methods We studied cases of hepatitis A and enteric fever notified through the National Surveillance System from January 1, 2004 through December 31, 2011. Results A total of 921 cases of hepatitis A and 106 cases of enteric fever were notified; of them, 88 (9.5%) and 46 (43.4%) were travel-associated, respectively. Travellers returning from Eastern Europe and the Middle East accounted for most imported cases of hepatitis A (37 (43.5%) and 14 (16.5%) cases, respectively). The Indian subcontinent was the prevalent area of acquisition of travel-associated enteric fever, followed by the Middle East (35 (83.3%) and 4 (9.5%) cases, respectively). Foreign-born travellers accounted for 43 (48.8%) and 39 (86.6%) cases of travel-associated hepatitis A and enteric fever, respectively. Children <15 years accounted for 65.1% of hepatitis A cases and 7.7% among foreign-born travellers. Greek Roma accounted for 270 (29.3%) of all hepatitis A cases notified. Conclusions International travels have a significant impact on the epidemiology of enteric fever in Greece, affecting mainly foreign travellers. Hepatitis A carries a significant burden of morbidity among Greek travellers and children of foreign nationality. There is a need to improve travel medicine services for travellers travelling to developing countries. JF - Travel Medicine and Infectious Disease AU - Maltezou, Helena C AU - Patrinos, Stavros AU - Veneti, Labrini AU - Gkolfinopoulou, Kassiani AU - Pavli, Androula AU - Mellou, Kassiani AU - Sideroglou, Theologia AU - Spilioti, Athina AU - Georgakopoulou, Theano AD - Department for Interventions in Health-Care Facilities, Hellenic Center for Disease Control and Prevention, 3-5 Agrafon Street, Athens 15123, Greece Y1 - 2014/03// PY - 2014 DA - Mar 2014 SP - 143 EP - 148 PB - Elsevier VL - 12 IS - 2 SN - 1477-8939, 1477-8939 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Hepatitis A KW - Enteric fever KW - Travel-associated KW - Imported KW - Greece KW - Travel KW - Hepatitis A virus KW - Travellers KW - Italy, Roma KW - Children KW - Morbidity KW - MED, Greece KW - Epidemiology KW - ANE, Europe KW - Typhoid fever KW - Developing countries KW - Middle East KW - Ethnic groups KW - H 12000:Epidemiology and Public Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1516745641?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Travel+Medicine+and+Infectious+Disease&rft.atitle=Hepatitis+A+and+enteric+fever+in+Greece%2C+2004-2011%3A+A+cross-sectional+analysis&rft.au=Maltezou%2C+Helena+C%3BPatrinos%2C+Stavros%3BVeneti%2C+Labrini%3BGkolfinopoulou%2C+Kassiani%3BPavli%2C+Androula%3BMellou%2C+Kassiani%3BSideroglou%2C+Theologia%3BSpilioti%2C+Athina%3BGeorgakopoulou%2C+Theano&rft.aulast=Maltezou&rft.aufirst=Helena&rft.date=2014-03-01&rft.volume=12&rft.issue=2&rft.spage=143&rft.isbn=&rft.btitle=&rft.title=Travel+Medicine+and+Infectious+Disease&rft.issn=14778939&rft_id=info:doi/10.1016%2Fj.tmaid.2013.10.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-04-01 N1 - Last updated - 2014-09-05 N1 - SubjectsTermNotLitGenreText - Travel; Epidemiology; Travellers; Hepatitis A; Children; Typhoid fever; Developing countries; Morbidity; Ethnic groups; Hepatitis A virus; MED, Greece; ANE, Europe; Italy, Roma; Middle East DO - http://dx.doi.org/10.1016/j.tmaid.2013.10.004 ER - TY - JOUR T1 - Changes in Knowledge of Bat Rabies and Human Exposure among United States Cavers AN - 1647024208; 21172726 AB - The purpose of the study was to evaluate changes in the knowledge of bat rabies and human exposure among United States cavers during the last decade. A survey was distributed among cavers who attended the National Speleological Society convention in 2000 and those who attended in 2010. In 2000 and 2010, 392 and 108 cavers, respectively, responded to the questionnaire. Eighty-five per cent of respondents in 2000 indicated a bat bite as a risk for rabies compared with all respondents in 2010 (P < 0.0001 controlling for age). The proportion of respondents indicating that they were advised to receive rabies pre-exposure prophylaxis (PreEP) because of caving increased (17% and 29%; P = 0.03 controlling for age). Among these, PreEP was received by 56% and 45%. Although recognition of the risk of rabies exposure from bats is important, the proportion of cavers acting on current recommendations regarding PreEP does not appear to have improved in the past decade. JF - American Journal of Tropical Medicine and Hygiene AU - Mehal, Jason M AU - Holman, Robert C AU - Brass, Danny A AU - Blanton, Jesse D AU - Petersen, Brett W AD - National Speleological Society, New Haven, Connecticut; Epidemic Intelligence Service, CDC, Atlanta, Georgia; Centers for Disease Control and Prevention (CDC), 1600 Clifton Road NE MS-A30, Atlanta, GA 30333, jmehal@cdc.gov Y1 - 2014/02// PY - 2014 DA - February 2014 SP - 263 EP - 264 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 90 IS - 2 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts; Risk Abstracts KW - Inventories KW - USA KW - Age KW - Bites KW - Rabies KW - Prophylaxis KW - K 03490:Miscellaneous KW - V 22410:Animal Diseases KW - J 02490:Miscellaneous KW - R2 23010:General: Models, forecasting UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1647024208?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Changes+in+Knowledge+of+Bat+Rabies+and+Human+Exposure+among+United+States+Cavers&rft.au=Mehal%2C+Jason+M%3BHolman%2C+Robert+C%3BBrass%2C+Danny+A%3BBlanton%2C+Jesse+D%3BPetersen%2C+Brett+W&rft.aulast=Mehal&rft.aufirst=Jason&rft.date=2014-02-01&rft.volume=90&rft.issue=2&rft.spage=263&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.13-0502 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Inventories; Age; Bites; Rabies; Prophylaxis; USA DO - http://dx.doi.org/10.4269/ajtmh.13-0502 ER - TY - JOUR T1 - Impact of Changes in Clostridium difficile Testing Practices on Stool Rejection Policies and C. difficile Positivity Rates across Multiple Laboratories in the United States AN - 1520372929; 19446513 AB - We describe the adoption of nucleic acid amplification tests (NAAT) for Clostridium difficile diagnosis and their impact on stool rejection policies and C. difficile positivity rates. Of the laboratories with complete surveys, 51 (43%) reported using NAAT in 2011. Laboratories using NAAT had stricter rejection policies and increased positivity rates. JF - Journal of Clinical Microbiology AU - Cohen, Jessica AU - Limbago, Brandi AU - Dumyati, Ghinwa AU - Holzbauer, Stacy AU - Johnston, Helen AU - Perlmutter, Rebecca AU - Dunn, John AU - Nadle, Joelle AU - Lyons, Carol AU - Phipps, Erin AD - Atlanta Research and Education Foundation, Atlanta, Georgia, USA, jcohen@cdc.gov. Y1 - 2014/02// PY - 2014 DA - February 2014 SP - 632 EP - 634 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 52 IS - 2 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - nucleic acids KW - Clostridium difficile KW - Adoption KW - Feces KW - J 02300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1520372929?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Impact+of+Changes+in+Clostridium+difficile+Testing+Practices+on+Stool+Rejection+Policies+and+C.+difficile+Positivity+Rates+across+Multiple+Laboratories+in+the+United+States&rft.au=Cohen%2C+Jessica%3BLimbago%2C+Brandi%3BDumyati%2C+Ghinwa%3BHolzbauer%2C+Stacy%3BJohnston%2C+Helen%3BPerlmutter%2C+Rebecca%3BDunn%2C+John%3BNadle%2C+Joelle%3BLyons%2C+Carol%3BPhipps%2C+Erin&rft.aulast=Cohen&rft.aufirst=Jessica&rft.date=2014-02-01&rft.volume=52&rft.issue=2&rft.spage=632&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.02177-13 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-04-01 N1 - Number of references - 18 N1 - Last updated - 2016-07-20 N1 - SubjectsTermNotLitGenreText - nucleic acids; Adoption; Feces; Clostridium difficile DO - http://dx.doi.org/10.1128/JCM.02177-13 ER - TY - JOUR T1 - Infections caused by carbapenem-resistant Klebsiella pneumoniae among patients in intensive care units in Greece: a multi-centre study on clinical outcome and therapeutic options AN - 1505334079; 19017297 AB - Infections due to carbapenem-resistant Klebsiella pneumoniae (CR-KP) have emerged as a public health problem worldwide given their spread dynamics and the limited therapeutic options. Our aim was to study the clinical outcome of patients with CR-KP infections in relation to antimicrobial treatment. CR-KP infections that occurred in a 10-month period (September 2009 to June 2010) in patients admitted to 19 intensive care units all over Greece were studied. A total of 127 CR-KP infections were reported. Central venous catheter bacteraemia was the most frequent infection, followed by ventilator-associated pneumonia (39 (30.7%) and 35 (27.6%) cases, respectively). Resistance to colistin, tigecycline, gentamicin and amikacin was detected in 20%, 33%, 21% and 64% of isolates, respectively. Regarding treatment, 107 cases received active treatment, including 1 or greater than or equal to 2 active antibiotics in 65 (60.7%) and 42 (39.3%) cases, respectively. The most frequent combination was colistin plus aminoglycoside and tigecycline plus aminoglycoside (17 and 11 cases, respectively). Forty-eight (45.2%) of the cases that received active treatment were considered clinical failures, with 23.5% mortality at 14 days. Logistic regression analysis revealed that age less than or equal to 55 years, non-immunocompromised patients and patients who received colistin had higher successful response rates, while patients less than or equal to 55 years old had lower mortality rates at 14 days after the introduction of active treatment. CR-KP infections are associated with a significant clinical failure rate. Colistin remains a valuable antimicrobial agent for treating these infections, while the rise of resistance to the last available antibiotics further limits treatment options. JF - Clinical Microbiology and Infection AU - Kontopidou, F AU - Giamarellou, H AU - Katerelos, P AU - Maragos, A AU - Kioumis, I AU - Trikka-Graphakos, E AU - Valakis, C AU - Maltezou, H C AD - Department for Interventions in Health-Care Facilities. Hellenic Center for Disease Control and Prevention Y1 - 2014/02// PY - 2014 DA - Feb 2014 SP - O117 EP - O123 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 20 IS - 2 SN - 1198-743X, 1198-743X KW - Microbiology Abstracts B: Bacteriology KW - Mortality KW - Age KW - Amikacin KW - tigecycline KW - Bacteremia KW - Antibiotics KW - Infection KW - Aminoglycoside antibiotics KW - Public health KW - Antimicrobial agents KW - Gentamicin KW - Colistin KW - ventilator-associated pneumonia KW - Intensive care units KW - Catheters KW - Regression analysis KW - Klebsiella pneumoniae KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1505334079?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+Microbiology+and+Infection&rft.atitle=Infections+caused+by+carbapenem-resistant+Klebsiella+pneumoniae+among+patients+in+intensive+care+units+in+Greece%3A+a+multi-centre+study+on+clinical+outcome+and+therapeutic+options&rft.au=Kontopidou%2C+F%3BGiamarellou%2C+H%3BKaterelos%2C+P%3BMaragos%2C+A%3BKioumis%2C+I%3BTrikka-Graphakos%2C+E%3BValakis%2C+C%3BMaltezou%2C+H+C&rft.aulast=Kontopidou&rft.aufirst=F&rft.date=2014-02-01&rft.volume=20&rft.issue=2&rft.spage=O117&rft.isbn=&rft.btitle=&rft.title=Clinical+Microbiology+and+Infection&rft.issn=1198743X&rft_id=info:doi/10.1111%2F1469-0691.12341 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-03-01 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - Mortality; Age; Amikacin; tigecycline; Bacteremia; Antibiotics; Infection; Aminoglycoside antibiotics; Antimicrobial agents; Public health; Colistin; Gentamicin; ventilator-associated pneumonia; Intensive care units; Regression analysis; Catheters; Klebsiella pneumoniae DO - http://dx.doi.org/10.1111/1469-0691.12341 ER - TY - JOUR T1 - 'Let Us Protect Our Future' a culturally congruent evidenced-based HIV/STD risk-reduction intervention for young South African adolescents AN - 1496893285; 19038030 AB - One of the worst HIV/AIDS epidemics in the world is occurring in South Africa, where heterosexual exposure is the main mode of HIV transmission. Young people 15-24 years of age, particularly women, account for a large share of new infections. Accordingly, there is an urgent need for behavior-change interventions to reduce the incidence of HIV among adolescents in South Africa. However, there are few such interventions with proven efficacy for South African adolescents, especially young adolescents. A recent cluster-randomized controlled trial of the 'Let Us Protect Our Future!' HIV/STD risk-reduction intervention for Grade 6 South African adolescents (mean age = 12.4 years) found significant decreases in self-reported sexual risk behaviors compared with a control intervention. This article describes the intervention, the use of the social cognitive theory and the reasoned action approach to develop the intervention, how formative research informed its development and the acceptability of the intervention. Challenges in designing and implementing HIV/STD risk-reduction interventions for young adolescents in sub-Saharan Africa are discussed. JF - Health Education Research AU - Jemmott, L S AU - Jemmott, J B AU - Ngwane, Z AU - Icard, L AU - O'Leary, A AU - Gueits, L AU - Brawner, B AD - super(1)School of Nursing, University of Pennsylvania, 418 Curie Boulevard, super(2)Department of Psychiatry, Perelman School of Medicine, and Center for Health Behavior and Communication Research, University of Pennsylvania, 3535 Market Street, Suite 520, Philadelphia, super(3)Department of Anthropology, Haverford College, Haverford, PA 19041, USA, super(4)College of Health Professions and Social Work, Temple University, Philadelphia, PA 19122, USA and super(5)National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA., jjemmott@asc.upenn.edu Y1 - 2014/02// PY - 2014 DA - Feb 2014 SP - 166 EP - 181 PB - Oxford University Press, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 29 IS - 1 SN - 0268-1153, 0268-1153 KW - Health & Safety Science Abstracts; Risk Abstracts KW - Acquired immune deficiency syndrome KW - Age KW - Acceptability KW - Intervention KW - Risk reduction KW - Infection KW - Clinical trials KW - Sexual behavior KW - Disease transmission KW - Education KW - Human immunodeficiency virus KW - South Africa KW - Sexually transmitted diseases KW - Adolescents KW - H 11000:Diseases/Injuries/Trauma KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1496893285?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+Education+Research&rft.atitle=%27Let+Us+Protect+Our+Future%27+a+culturally+congruent+evidenced-based+HIV%2FSTD+risk-reduction+intervention+for+young+South+African+adolescents&rft.au=Jemmott%2C+L+S%3BJemmott%2C+J+B%3BNgwane%2C+Z%3BIcard%2C+L%3BO%27Leary%2C+A%3BGueits%2C+L%3BBrawner%2C+B&rft.aulast=Jemmott&rft.aufirst=L&rft.date=2014-02-01&rft.volume=29&rft.issue=1&rft.spage=166&rft.isbn=&rft.btitle=&rft.title=Health+Education+Research&rft.issn=02681153&rft_id=info:doi/10.1093%2Fher%2Fcyt072 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-02-01 N1 - Last updated - 2014-09-05 N1 - SubjectsTermNotLitGenreText - Age; Acquired immune deficiency syndrome; Acceptability; Intervention; Risk reduction; Infection; Sexual behavior; Clinical trials; Disease transmission; Education; Human immunodeficiency virus; Adolescents; Sexually transmitted diseases; South Africa DO - http://dx.doi.org/10.1093/her/cyt072 ER - TY - JOUR T1 - Heat Illness: Predictors of Hospital Admissions Among Emergency Department Visits-Georgia, 2002-2008 AN - 1496888175; 19008174 AB - Heat-related illnesses (HRI) are the most frequent cause of environmental exposure-related injury treated in US emergency departments (ED). While most individuals with HRI evaluated in EDs are discharged to home, understanding predictors of individuals hospitalized with HRI may help public health practitioners and medical providers identify high risk groups who would benefit from educational outreach. We analyzed data collected by the Georgia Department of Public Health, Office of Health Indicators for Planning, regarding ED and hospital discharges for HRI, as identified by ICD-9 codes, between 2002 and 2008 to determine characteristics of individuals receiving care in EDs. Temperature data from CDC's Environmental Public Health Tracking Network were linked to the dataset to determine if ED visits occurred during an extreme heat event (EHE). A multivariable logistic regression model was developed to determine characteristics predicting hospitalization versus ED discharge using demographic characteristics, comorbid conditions, socioeconomic status, the public health district of residence, and the presence of an EHE. Men represented the majority of ED visits (75 %) and hospitalizations (78 %). In the multivariable model, the odds of admission versus ED discharge with an associated HRI increased with age among both men and women, and odds were higher among residents of specific public health districts, particularly in the southern part of the state. Educational efforts targeting the specific risk groups identified by this study may help reduce the burden of hospitalization due to HRI in the state of Georgia. JF - Journal of Community Health AU - Pillai, Satish K AU - Noe, Rebecca S AU - Murphy, Matthew W AU - Vaidyanathan, Ambarish AU - Young, Randall AU - Kieszak, Stephanie AU - Freymann, Gordon AU - Smith, Wendy AU - Drenzek, Cherie AU - Lewis, Lauren AU - Wolkin, Amy F AD - Division of Preparedness and Emerging Infections, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, MS C-18, Atlanta, GA, 30329, USA, vig8@cdc.gov Y1 - 2014/02// PY - 2014 DA - Feb 2014 SP - 90 EP - 98 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 39 IS - 1 SN - 0094-5145, 0094-5145 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Demography KW - Data collection KW - Age KW - Injuries KW - Temperature KW - Heat tolerance KW - Socioeconomics KW - USA, Georgia KW - Public health KW - Hospitals KW - Emergency medical services KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1496888175?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Community+Health&rft.atitle=Heat+Illness%3A+Predictors+of+Hospital+Admissions+Among+Emergency+Department+Visits-Georgia%2C+2002-2008&rft.au=Pillai%2C+Satish+K%3BNoe%2C+Rebecca+S%3BMurphy%2C+Matthew+W%3BVaidyanathan%2C+Ambarish%3BYoung%2C+Randall%3BKieszak%2C+Stephanie%3BFreymann%2C+Gordon%3BSmith%2C+Wendy%3BDrenzek%2C+Cherie%3BLewis%2C+Lauren%3BWolkin%2C+Amy+F&rft.aulast=Pillai&rft.aufirst=Satish&rft.date=2014-02-01&rft.volume=39&rft.issue=1&rft.spage=90&rft.isbn=&rft.btitle=&rft.title=Journal+of+Community+Health&rft.issn=00945145&rft_id=info:doi/10.1007%2Fs10900-013-9743-4 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-02-01 N1 - Number of references - 17 N1 - Last updated - 2014-08-21 N1 - SubjectsTermNotLitGenreText - Demography; Age; Data collection; Injuries; Heat tolerance; Temperature; Socioeconomics; Emergency medical services; Hospitals; Public health; USA, Georgia DO - http://dx.doi.org/10.1007/s10900-013-9743-4 ER - TY - JOUR T1 - CD4 super(+) cell count, viral load, and drug resistance patterns among heterosexual breakthrough HIV infections in a study of oral preexposure prophylaxis AN - 1765970000; PQ0002559364 AB - We examined CD4 super(+) cell count and plasma viral load patterns among Botswana TDF/ FTC Oral FHIV Prophylaxis Trial (TDF2 study) participants who seroconverted, comparing participants assigned to receive tenofovir/emtricitabine with participants assigned to receive placebo. We also evaluated for antiretroviral drug resistance among the breakthrough HIV infections. Among nine seroconverters assigned to tenofovir/emtricitabine and 24 to placebo, there were no significant differences in their CD4 super(+) cell count or viral load profiles over time. Of the four participants who seroconverted onstudy while receiving tenofovir/emtricitabine, none became infected as a result of drugresistant HIV; moreover, no resistance mutations emerged following seroconversion. JF - AIDS AU - Chirwa, Lovemore I AU - Johnson, Jeffrey A AU - Niska, Richard W AU - Segolodi, Tebogo M AU - Henderson, Faith L AU - Rose, Charles E AU - Li, Jin-fen AU - Thigpen, Michael C AU - Matlhaba, Onkabetse AU - Paxton, Lynn A AU - Brooks, John T AD - CDC-BOTUSA, Gaborone, Botswana, jjohnson1@cdc.gov Y1 - 2014/01/14/ PY - 2014 DA - 2014 Jan 14 SP - 223 EP - 226 PB - Lippincott Williams & Wilkins, Inc, 530 Walnut Street Philadelphia PA 19106-3621 United States VL - 28 IS - 2 SN - 0269-9370, 0269-9370 KW - Health & Safety Science Abstracts; Immunology Abstracts; Virology & AIDS Abstracts KW - CD4+ cell KW - HIV drug resistance KW - HIV seroconversion KW - oral preexposure prophylaxis KW - viral load KW - Acquired immune deficiency syndrome KW - Drug resistance KW - tenofovir KW - Infection KW - CD4 antigen KW - Emtricitabine KW - Antiviral agents KW - Human immunodeficiency virus KW - Prophylaxis KW - Botswana KW - Seroconversion KW - Mutation KW - V 22360:AIDS and HIV KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1765970000?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS&rft.atitle=CD4+super%28%2B%29+cell+count%2C+viral+load%2C+and+drug+resistance+patterns+among+heterosexual+breakthrough+HIV+infections+in+a+study+of+oral+preexposure+prophylaxis&rft.au=Chirwa%2C+Lovemore+I%3BJohnson%2C+Jeffrey+A%3BNiska%2C+Richard+W%3BSegolodi%2C+Tebogo+M%3BHenderson%2C+Faith+L%3BRose%2C+Charles+E%3BLi%2C+Jin-fen%3BThigpen%2C+Michael+C%3BMatlhaba%2C+Onkabetse%3BPaxton%2C+Lynn+A%3BBrooks%2C+John+T&rft.aulast=Chirwa&rft.aufirst=Lovemore&rft.date=2014-01-14&rft.volume=28&rft.issue=2&rft.spage=223&rft.isbn=&rft.btitle=&rft.title=AIDS&rft.issn=02699370&rft_id=info:doi/10.1097%2FQAD.0000000000000102 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-02-01 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - CD4 antigen; Antiviral agents; Emtricitabine; Drug resistance; Prophylaxis; Seroconversion; tenofovir; Infection; Mutation; Acquired immune deficiency syndrome; Human immunodeficiency virus; Botswana DO - http://dx.doi.org/10.1097/QAD.0000000000000102 ER - TY - JOUR T1 - Serological Analysis of Test Results of Suspected Measles and Rubella in Yuexiu District of Guangzhou in 2012 AN - 1832247098; PQ0002350826 AB - Objective: To collect and analyze the serological results of suspected measles and rubella in Yuexiu District of Guangzhou in 2011 and understand the epidemic characteristics of measles and rubella. Methods: Selected of 166 cases of suspected measles and rubella serum of patients from January 2012 to December 2012 as research subjects, counted the antibody detection of IgM masculine and the cases and constituentratio of IgM masculine in each age and month. Results: 36.1% patients of suspected measles and rubella were detected IgM masculine and there was a higher detection rate (up to 44.4%) in infants aged 0-1 years in then, December, August and May was a good fat period of measles. The highest detection rate of IgM masculine of rubella(up to 75.0%) were the middle-aged and elderly patients(>20 years old) and July, April and May was susceptible to rubella. Conclusion: There is a higher detection rate of IgM antibody masculine in suspected measles and rubella, 0-1 years old infants and the middle-aged and elderly patients(>20 years old) are major groups of measles and rubella, April to May, July to August and December is the peak period of onset, should pay attention to strengthening prevention. JF - Progress In Modern Biomedicine AU - Wu, Gui-fen AU - Shi, Ting-ting AU - Ren, Mei-ling AU - Liang, Xuan AU - Wang, Fang AU - Shen, Juan AD - Department of Microbiology Laboratory, Center for Disease Control in Yuexiu District of Guangzhou Y1 - 2014///0, PY - 2014 DA - 0, 2014 PB - Progress in Modern Biomedicine, 184 Hua-yuan St Harbin City, Heilongjiang 150001 China VL - 14 IS - 5 SN - 1673-6273, 1673-6273 KW - Virology & AIDS Abstracts; Biotechnology and Bioengineering Abstracts KW - Measles KW - Rubella KW - Suspected cases KW - Serological KW - Age KW - Epidemics KW - Geriatrics KW - Immunoglobulin M KW - Infants KW - V 22400:Human Diseases KW - W 30900:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1832247098?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Progress+In+Modern+Biomedicine&rft.atitle=Serological+Analysis+of+Test+Results+of+Suspected+Measles+and+Rubella+in+Yuexiu+District+of+Guangzhou+in+2012&rft.au=Wu%2C+Gui-fen%3BShi%2C+Ting-ting%3BRen%2C+Mei-ling%3BLiang%2C+Xuan%3BWang%2C+Fang%3BShen%2C+Juan&rft.aulast=Wu&rft.aufirst=Gui-fen&rft.date=2014-01-01&rft.volume=14&rft.issue=5&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Progress+In+Modern+Biomedicine&rft.issn=16736273&rft_id=info:doi/ LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-10-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Age; Epidemics; Measles; Geriatrics; Rubella; Immunoglobulin M; Infants ER - TY - JOUR T1 - Epidemiological characteristics of malarias in Henan Province in 2011 and 2012 AN - 1727698989; PQ0001341318 AB - Aim: To analyze the epidemiological characteristics of malaria in Henan Province in 2011 and 2012. Methods: Data of the malaria in 2011 and 2012 in Henan Province were collected. Descriptive epidemiological analysis method was used to analsize the types and distribution characteristics. Results: A total of 314 (including 146 cases of imported malarias) and 156(imported malarias) malaria cases were reported and the annual incidence were 0.33 and 0.17 per 100 000 in 2011 and 2012 in Henan Province, respectively. The proportion of subtertian malaria, ovale malaria and malarial malaria in 2012 were more, the cases of tertian malaria were lower compared with those in 2011. Young and middle-aged males were the major population in the cases. The rate of male/female was 3.24:1 in 2011 and 38.00:1 in 2012, respectively. Farmers, workers and migrant workers were the top three. The cases were reported every month. The imported cases were infected mainly from the malaria epidemic regions such as Africa and SE. Asia. Conclusion: The malaria situation drops obviously in Henan Province, but the imported malaria cases increase. JF - Zhengzhou Daxue Xuebao (Yixue Ban) - Journal of Zhengzhou University. Medical sciences AU - YANG, Chengyun AU - LU, Deling AU - ZHOU, Ruimin AU - LIU, Ying AU - ZHANG, Hongwei AU - ZHAO, Yuling AD - Parasite Disease Institute, Center for Disease Control and Prevention of Henan Province, Zhengzhou 450016, tochyun163.com Y1 - 2014///0, PY - 2014 DA - 0, 2014 SP - 815 EP - 818 PB - Zhengzhou Daxue VL - 49 IS - 6 SN - 1671-6825, 1671-6825 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources KW - Henan Province KW - malaria epidemic situation KW - imported malaria KW - Human diseases KW - Epidemics KW - Africa KW - Malaria KW - Asia KW - Q5 08524:Public health, medicines, dangerous organisms KW - Q1 08102:Institutes and organizations UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1727698989?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Zhengzhou+Daxue+Xuebao+%28Yixue+Ban%29+-+Journal+of+Zhengzhou+University.+Medical+sciences&rft.atitle=Epidemiological+characteristics+of+malarias+in+Henan+Province+in+2011+and+2012&rft.au=YANG%2C+Chengyun%3BLU%2C+Deling%3BZHOU%2C+Ruimin%3BLIU%2C+Ying%3BZHANG%2C+Hongwei%3BZHAO%2C+Yuling&rft.aulast=YANG&rft.aufirst=Chengyun&rft.date=2014-01-01&rft.volume=49&rft.issue=6&rft.spage=815&rft.isbn=&rft.btitle=&rft.title=Zhengzhou+Daxue+Xuebao+%28Yixue+Ban%29+-+Journal+of+Zhengzhou+University.+Medical+sciences&rft.issn=16716825&rft_id=info:doi/10.13705%2Fj.issn.1671-6825.2014.06.013 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-10-01 N1 - Last updated - 2016-02-04 N1 - SubjectsTermNotLitGenreText - Human diseases; Epidemics; Malaria; Africa; Asia DO - http://dx.doi.org/10.13705/j.issn.1671-6825.2014.06.013 ER - TY - JOUR T1 - Prokaryotic expression and antigenicity analysis of Mycobacterium tuberculosis fbpB encoding protein AN - 1687670043; PQ0001541602 AB - Aim: To construct His-tag prokaryotic expression plasmid of the fbpB gene of Mycobacterium tuberculosis, and to express the fusion protein efficiently in E. coli BL21. Methods: The fbpB gene was amplified by PCR from genomic DNA of Mycobacterium tuberculosis H37Rv strain, and was cloned into pET28a expression vector. E. coli BL21 strain was transformed with the recombinant vector that conformed by sequencing and induced to express recombinant protein. The recombinant protein was confirmed by SDS-PAGE and immunoblot, and its antigenicity was analyzed by ELISA assay. Results: The fbpB gene was amplified by PCR and the recombinant expressive vector pET28a-fgbB was constructed. The E. coli BL21 strains with recombinant vector showed high level expression of Ag85B fusion protein after IPTG induction. Conclusion: The purified fusion protein could be specifically recognized by sera of patients with tuberculosis. The expression of recombinant Ag85B protein lays a basis for further studies on immunological mechanism of Mycobacterium tuberculosis. JF - Zhengzhou Daxue Xuebao (Yixue Ban) - Journal of Zhengzhou University. Medical sciences AU - SHI, Jie AU - ZHU, Yankun AU - MA, Xiaoguang AU - WANG, Shaohua AU - LI, Hui AU - XING, Jin AU - YAN, Guorui AU - JIN, Xiaowei AD - Henan Province Center for Disease Control and Prevention, Zhengzhou 450016 Y1 - 2014 PY - 2014 DA - 2014 SP - 741 EP - 744 PB - Zhengzhou Daxue VL - 49 IS - 5 SN - 1671-6825, 1671-6825 KW - Microbiology Abstracts B: Bacteriology KW - Mycobacterium tuberculosis KW - fgbB gene KW - prokaryotic expression KW - antituberculous immunity KW - antigenic 85 protein KW - Expression vectors KW - Enzyme-linked immunosorbent assay KW - Antigenicity KW - Escherichia coli KW - Polymerase chain reaction KW - Tuberculosis KW - Fusion protein KW - genomics KW - Ag85B protein KW - Plasmids KW - J 02350:Immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1687670043?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Zhengzhou+Daxue+Xuebao+%28Yixue+Ban%29+-+Journal+of+Zhengzhou+University.+Medical+sciences&rft.atitle=Prokaryotic+expression+and+antigenicity+analysis+of+Mycobacterium+tuberculosis+fbpB+encoding+protein&rft.au=SHI%2C+Jie%3BZHU%2C+Yankun%3BMA%2C+Xiaoguang%3BWANG%2C+Shaohua%3BLI%2C+Hui%3BXING%2C+Jin%3BYAN%2C+Guorui%3BJIN%2C+Xiaowei&rft.aulast=SHI&rft.aufirst=Jie&rft.date=2014-01-01&rft.volume=49&rft.issue=5&rft.spage=741&rft.isbn=&rft.btitle=&rft.title=Zhengzhou+Daxue+Xuebao+%28Yixue+Ban%29+-+Journal+of+Zhengzhou+University.+Medical+sciences&rft.issn=16716825&rft_id=info:doi/10.13705%2Fj.issn.1671-6825.2014.05.041 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-06-01 N1 - Last updated - 2015-11-16 N1 - SubjectsTermNotLitGenreText - Expression vectors; Enzyme-linked immunosorbent assay; Antigenicity; Polymerase chain reaction; Tuberculosis; genomics; Fusion protein; Plasmids; Ag85B protein; Escherichia coli; Mycobacterium tuberculosis DO - http://dx.doi.org/10.13705/j.issn.1671-6825.2014.05.041 ER - TY - JOUR T1 - Severe Plasmodium vivax Malaria Complicated with Acute Respiratory Distress Syndrome: A Case Associated with Focal Autochthonous Transmission in Greece AN - 1668245977; PQ0001216930 AB - In 2011, autochthonous Plasmodium vivax malaria emerged in a focal geographical area in Greece after importation by immigrants from the Indian subcontinent. We report the case of complicated P. vivax malaria in a previously healthy 42-year-old Greek female. The patient presented acute respiratory distress syndrome (ARDS), worsening jaundice, and thrombocytopenia after the administration of antimalarial treatment and despite a decreasing burden of parasitemia. She recovered fully after admission in the intensive care unit and support with mechanical ventilation. We discuss the risks potentially associated with the reappearance of P. vivax malaria in a previously malaria-free area. JF - Vector Borne and Zoonotic Diseases AU - Gougoutsi, Alexandra AU - Karageorgopoulos, Drosos E AU - Dimitriadou, Areti AU - Melas, Nikolaos AU - Kranidiotis, Georgios AU - Voutsinas, Dionysios AU - Melidonis, Andreas AD - Department of Internal Medicine, Tzaneio General Hospital, Piraeus, Greece; Hellenic Center for Disease Control and Prevention, Athens, Greece Y1 - 2014 PY - 2014 DA - 2014 SP - 378 EP - 381 PB - Mary Ann Liebert, Inc., 2 Madison Ave Larchmont NY 10538-1962 United States VL - 14 IS - 5 SN - 1530-3667, 1530-3667 KW - Health & Safety Science Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Acute respiratory distress syndrome KW - Malaria KW - Vivax KW - Pulmonary complications KW - Mechanical ventilation KW - Critical illness KW - Severe malaria KW - Ventilation KW - Immigrants KW - Vectors KW - Plasmodium vivax KW - Importation KW - Disease transmission KW - MED, Greece KW - parasitemia KW - Thrombocytopenia KW - Intensive care units KW - Respiratory distress syndrome KW - Jaundice KW - K 03400:Human Diseases KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1668245977?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vector+Borne+and+Zoonotic+Diseases&rft.atitle=Severe+Plasmodium+vivax+Malaria+Complicated+with+Acute+Respiratory+Distress+Syndrome%3A+A+Case+Associated+with+Focal+Autochthonous+Transmission+in+Greece&rft.au=Gougoutsi%2C+Alexandra%3BKarageorgopoulos%2C+Drosos+E%3BDimitriadou%2C+Areti%3BMelas%2C+Nikolaos%3BKranidiotis%2C+Georgios%3BVoutsinas%2C+Dionysios%3BMelidonis%2C+Andreas&rft.aulast=Gougoutsi&rft.aufirst=Alexandra&rft.date=2014-01-01&rft.volume=14&rft.issue=5&rft.spage=378&rft.isbn=&rft.btitle=&rft.title=Vector+Borne+and+Zoonotic+Diseases&rft.issn=15303667&rft_id=info:doi/10.1089%2Fvbz.2012.1192 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Last updated - 2015-10-28 N1 - SubjectsTermNotLitGenreText - parasitemia; Thrombocytopenia; Intensive care units; Ventilation; Immigrants; Vectors; Respiratory distress syndrome; Malaria; Importation; Jaundice; Disease transmission; Plasmodium vivax; MED, Greece DO - http://dx.doi.org/10.1089/vbz.2012.1192 ER - TY - JOUR T1 - Flight related tuberculosis contact investigations in the United States: Comparative risk and economic analysis of alternate protocols AN - 1660414255; PQ0001035688 AB - Background In-flight transmission risk of Mycobacterium tuberculosis is not well defined, although studies suggest it is low. The impact of flight-related tuberculosis (TB) contact investigations (TBCIs) on TB prevention and control is not well established, and they compete for resources with activities with established benefits. We sought to determine the risks and cost-benefits of using more restrictive criteria in comparison to the Centers for Disease Control and Prevention (CDC) 2008 protocol for TBCIs. Methods The risk-benefits of a modified CDC protocol were analyzed in comparison to the 2008 CDC protocol using data from flight-related TBCIs conducted in the United States from 2007 through 2009. We predicted the numbers and characteristics of case-travelers that would be identified using each protocol's criteria, and results of the associated passenger-contacts' TB screening tests. The economic analysis compared the costs of TBCIs to avoided costs of TB treatment and mortality using a Return on Investment model. Results The estimated in-flight transmission risk using a modified CDC protocol was 1.4%-19% versus 1.1%-24% for the 2008 protocol. Numbers of TBCIs and immediate costs to health departments were reduced by half. Long-term cost-benefits were comparable. Conclusions CDC's modified protocol appears to be a feasible alternative that will conserve public health resources without jeopardizing the public's health. JF - Travel Medicine and Infectious Disease AU - Marienau, Karen J AU - Cramer, Elaine H AU - Coleman, Margaret S AU - Marano, Nina AU - Cetron, Martin S AD - Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic, Infectious Diseases, Division of Global Migration and Quarantine, Atlanta, GA, USA Y1 - 2014/01// PY - 2014 DA - January 2014 SP - 54 EP - 62 PB - Elsevier VL - 12 IS - 1 SN - 1477-8939, 1477-8939 KW - Microbiology Abstracts B: Bacteriology KW - Tuberculosis KW - TB KW - Air travel KW - Contact investigation KW - Transmission risk KW - Cost-benefit analysis KW - Travel KW - Flight KW - Mortality KW - Data processing KW - Economics KW - Disease control KW - Mycobacterium tuberculosis KW - Public health KW - Models KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1660414255?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Travel+Medicine+and+Infectious+Disease&rft.atitle=Flight+related+tuberculosis+contact+investigations+in+the+United+States%3A+Comparative+risk+and+economic+analysis+of+alternate+protocols&rft.au=Marienau%2C+Karen+J%3BCramer%2C+Elaine+H%3BColeman%2C+Margaret+S%3BMarano%2C+Nina%3BCetron%2C+Martin+S&rft.aulast=Marienau&rft.aufirst=Karen&rft.date=2014-01-01&rft.volume=12&rft.issue=1&rft.spage=54&rft.isbn=&rft.btitle=&rft.title=Travel+Medicine+and+Infectious+Disease&rft.issn=14778939&rft_id=info:doi/10.1016%2Fj.tmaid.2013.09.007 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Number of references - 35 N1 - Last updated - 2016-07-20 N1 - SubjectsTermNotLitGenreText - Flight; Travel; Mortality; Data processing; Economics; Disease control; Tuberculosis; Models; Public health; Mycobacterium tuberculosis DO - http://dx.doi.org/10.1016/j.tmaid.2013.09.007 ER - TY - JOUR T1 - Repeated measures study of weekly and daily cytomegalovirus shedding patterns in saliva and urine of healthy cytomegalovirus-seropositive children AN - 1635026819; 21034081 AB - Background: To better understand potential transmission risks from contact with the body fluids of children, we monitored the presence and amount of CMV shedding over time in healthy CMV-seropositive children. Methods: Through screening we identified 36 children from the Atlanta, Georgia area who were CMV-seropositive, including 23 who were shedding CMV at the time of screening. Each child received 12 weekly in-home visits at which field workers collected saliva and urine. During the final two weeks, parents also collected saliva and urine daily. Results: Prevalence of shedding was highly correlated with initial shedding status: children shedding at the screening visit had CMV DNA in 84% of follow-up saliva specimens (455/543) and 28% of follow-up urine specimens (151/539); those not shedding at the screening visit had CMV DNA in 16% of follow-up saliva specimens (47/303) and 5% of follow-up urine specimens (16/305). Among positive specimens we found median viral loads of 82,900 copies/mL in saliva and 34,730 copies/mL in urine (P = 0.01), while the viral load for the 75th percentile was nearly 1.5 million copies/mL for saliva compared to 86,800 copies/mL for urine. Younger age was significantly associated with higher viral loads, especially for saliva (P < 0.001). Shedding prevalence and viral loads were relatively stable over time. All children who were shedding at the screening visit were still shedding at least some days during weeks 11 and 12, and median and mean viral loads did not change substantially over time. Conclusions: Healthy CMV-seropositive children can shed CMV for months at high, relatively stable levels. These data suggest that behavioral prevention messages need to address transmission via both saliva and urine, but also need to be informed by the potentially higher risks posed by saliva and by exposures to younger children. JF - BMC Infectious Diseases AU - Cannon, Michael J AU - Stowell, Jennifer D AU - Clark, Rebekah AU - Dollard, Philip R AU - Johnson, Delaney AU - Mask, Karen AU - Stover, Cynthia AU - Wu, Karen AU - Amin, Minal AU - Hendley, Will AU - Guo, Jing AU - Schmid, D Scott AU - Dollard, Sheila C AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 1600 Clifton Road, Mailstop E-86, Atlanta 30333, GA, USA Y1 - 2014 PY - 2014 DA - 2014 SP - 569 PB - BioMed Central Ltd., Middlesex House London W1T 4LB United Kingdom VL - 14 IS - 1 SN - 1471-2334, 1471-2334 KW - Virology & AIDS Abstracts; Risk Abstracts KW - Cytomegalovirus KW - Congenital KW - Awareness KW - Behavior KW - Pregnancy KW - Age KW - Data processing KW - Risk taking KW - Children KW - Workers KW - Prevention KW - Infectious diseases KW - Urine KW - Risk factors KW - DNA KW - USA, Georgia, Atlanta KW - Saliva KW - Body fluids KW - R2 23060:Medical and environmental health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1635026819?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=BMC+Infectious+Diseases&rft.atitle=Repeated+measures+study+of+weekly+and+daily+cytomegalovirus+shedding+patterns+in+saliva+and+urine+of+healthy+cytomegalovirus-seropositive+children&rft.au=Cannon%2C+Michael+J%3BStowell%2C+Jennifer+D%3BClark%2C+Rebekah%3BDollard%2C+Philip+R%3BJohnson%2C+Delaney%3BMask%2C+Karen%3BStover%2C+Cynthia%3BWu%2C+Karen%3BAmin%2C+Minal%3BHendley%2C+Will%3BGuo%2C+Jing%3BSchmid%2C+D+Scott%3BDollard%2C+Sheila+C&rft.aulast=Cannon&rft.aufirst=Michael&rft.date=2014-01-01&rft.volume=14&rft.issue=1&rft.spage=569&rft.isbn=&rft.btitle=&rft.title=BMC+Infectious+Diseases&rft.issn=14712334&rft_id=info:doi/10.1186%2Fs12879-014-0569-1 L2 - http://www.biomedcentral.com/1471-2334/14/569 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-12-01 N1 - Number of references - 31 N1 - Last updated - 2015-03-04 N1 - SubjectsTermNotLitGenreText - Workers; Age; Data processing; Urine; Risk factors; DNA; Saliva; Children; Body fluids; Prevention; Infectious diseases; Risk taking; Cytomegalovirus; USA, Georgia, Atlanta DO - http://dx.doi.org/10.1186/s12879-014-0569-1 ER - TY - JOUR T1 - Cross-sectional study of cytomegalovirus shedding and immunological markers among seropositive children and their mothers AN - 1635019340; 21017691 AB - Background: Congenital cytomegalovirus (CMV) is the leading infectious cause of birth defects in the United States. To better understand factors that may influence CMV transmission risk, we compared viral and immunological factors in healthy children and their mothers. Methods: We screened for CMV IgG antibodies in a convenience sample of 161 children aged 0-47 months from the Atlanta, Georgia metropolitan area, along with 32 mothers of children who screened CMV-seropositive. We assessed CMV shedding via PCR using saliva collected with oral swabs (children and mothers) and urine collected from diapers using filter paper inserts (children only). Results: CMV IgG was present in 31% (50/161) of the children. Half (25/50) of seropositive children were shedding in at least one fluid. The proportion of seropositive children who shed in saliva was 100% (8/8) among the 4-12 month-olds, 64% (9/14) among 13-24 month-olds, and 40% (6/15) among 25-47 month-olds (P for trend = 0.003). Seropositive mothers had a lower proportion of saliva shedding (21% [6/29]) than children (P one million copies/mL) were only found in children's saliva (31% of those shedding); children's urine and mothers' saliva specimens all had fewer than 100,000 copies/mL. Low IgG avidity, a marker of primary infection, was associated with younger age (p = 0.03), higher viral loads in saliva (p = 0.02), and lower antibody titers (p = 0.005). Conclusions: Young CMV seropositive children, especially those less than one year-old may present high-risk CMV exposures to pregnant women, especially via saliva, though further research is needed to see if this finding can be generalized across racial or other demographic strata. JF - BMC Infectious Diseases AU - Stowell, Jennifer D AU - Mask, Karen AU - Amin, Minal AU - Clark, Rebekah AU - Levis, Denise AU - Hendley, Will AU - Lanzieri, Tatiana M AU - Dollard, Sheila C AU - Cannon, Michael J AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, MS E-86, Atlanta 30333, GA, USA Y1 - 2014 PY - 2014 DA - 2014 SP - 568 PB - BioMed Central Ltd., Middlesex House London W1T 4LB United Kingdom VL - 14 IS - 1 SN - 1471-2334, 1471-2334 KW - Virology & AIDS Abstracts; Immunology Abstracts; Risk Abstracts KW - Congenital KW - Cytomegalovirus KW - Transmission KW - Pregnancy KW - Children KW - Risk assessment KW - Age KW - Infection KW - Demography KW - Infectious diseases KW - Avidity KW - Risk factors KW - Risk groups KW - Congenital defects KW - Polymerase chain reaction KW - Filters KW - Urine KW - Filter paper KW - Immunoglobulin G KW - USA, Georgia, Atlanta KW - Saliva KW - Metropolitan areas KW - Infants KW - R2 23060:Medical and environmental health KW - F 06910:Microorganisms & Parasites KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1635019340?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=BMC+Infectious+Diseases&rft.atitle=Cross-sectional+study+of+cytomegalovirus+shedding+and+immunological+markers+among+seropositive+children+and+their+mothers&rft.au=Stowell%2C+Jennifer+D%3BMask%2C+Karen%3BAmin%2C+Minal%3BClark%2C+Rebekah%3BLevis%2C+Denise%3BHendley%2C+Will%3BLanzieri%2C+Tatiana+M%3BDollard%2C+Sheila+C%3BCannon%2C+Michael+J&rft.aulast=Stowell&rft.aufirst=Jennifer&rft.date=2014-01-01&rft.volume=14&rft.issue=1&rft.spage=568&rft.isbn=&rft.btitle=&rft.title=BMC+Infectious+Diseases&rft.issn=14712334&rft_id=info:doi/10.1186%2Fs12879-014-0568-2 L2 - http://www.biomedcentral.com/1471-2334/14/568 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-12-01 N1 - Number of references - 52 N1 - Last updated - 2015-03-20 N1 - SubjectsTermNotLitGenreText - Age; Children; Infection; Pregnancy; Demography; Urine; Avidity; Immunoglobulin G; Filter paper; Polymerase chain reaction; Congenital defects; Risk groups; Saliva; Infants; Risk assessment; Filters; Infectious diseases; Risk factors; Metropolitan areas; Cytomegalovirus; USA, Georgia, Atlanta DO - http://dx.doi.org/10.1186/s12879-014-0568-2 ER - TY - JOUR T1 - Estimates of the reproduction number for seasonal, pandemic, and zoonotic influenza: a systematic review of the literature AN - 1566843775; 20755230 AB - Background: The potential impact of an influenza pandemic can be assessed by calculating a set of transmissibility parameters, the most important being the reproduction number (R), which is defined as the average number of secondary cases generated per typical infectious case. Methods: We conducted a systematic review to summarize published estimates of R for pandemic or seasonal influenza and for novel influenza viruses (e.g. H5N1). We retained and summarized papers that estimated R for pandemic or seasonal influenza or for human infections with novel influenza viruses. Results: The search yielded 567 papers. Ninety-one papers were retained, and an additional twenty papers were identified from the references of the retained papers. Twenty-four studies reported 51 R values for the 1918 pandemic. The median R value for 1918 was 1.80 (interquartile range [IQR]: 1.47-2.27). Six studies reported seven 1957 pandemic R values. The median R value for 1957 was 1.65 (IQR: 1.53-1.70). Four studies reported seven 1968 pandemic R values. The median R value for 1968 was 1.80 (IQR: 1.56-1.85). Fifty-seven studies reported 78 2009 pandemic R values. The median R value for 2009 was 1.46 (IQR: 1.30-1.70) and was similar across the two waves of illness: 1.46 for the first wave and 1.48 for the second wave. Twenty-four studies reported 47 seasonal epidemic R values. The median R value for seasonal influenza was 1.28 (IQR: 1.19-1.37). Four studies reported six novel influenza R values. Four out of six R values were <1. Conclusions: These R values represent the difference between epidemics that are controllable and cause moderate illness and those causing a significant number of illnesses and requiring intensive mitigation strategies to control. Continued monitoring of R during seasonal and novel influenza outbreaks is needed to document its variation before the next pandemic. JF - BMC Infectious Diseases AU - Biggerstaff, Matthew AU - Cauchemez, Simon AU - Reed, Carrie AU - Gambhir, Manoj AU - Finelli, Lyn AD - Epidemiology and Prevention Branch, Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road NE MS A-32, Atlanta 30333, Georgia Y1 - 2014 PY - 2014 DA - 2014 SP - 480 PB - BioMed Central Ltd., Middlesex House London W1T 4LB United Kingdom VL - 14 IS - 1 SN - 1471-2334, 1471-2334 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Reproductive number KW - Influenza KW - Pandemics KW - Zoonotic influenza KW - Mitigation KW - Epidemics KW - Influenza A KW - Viruses KW - Infection KW - pandemics KW - Sulfur dioxide KW - Infectious diseases KW - Literature reviews KW - Reviews KW - Waves KW - Reproduction KW - Outbreaks KW - Seasonal variations KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - V 22490:Miscellaneous UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1566843775?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=BMC+Infectious+Diseases&rft.atitle=Estimates+of+the+reproduction+number+for+seasonal%2C+pandemic%2C+and+zoonotic+influenza%3A+a+systematic+review+of+the+literature&rft.au=Biggerstaff%2C+Matthew%3BCauchemez%2C+Simon%3BReed%2C+Carrie%3BGambhir%2C+Manoj%3BFinelli%2C+Lyn&rft.aulast=Biggerstaff&rft.aufirst=Matthew&rft.date=2014-01-01&rft.volume=14&rft.issue=1&rft.spage=480&rft.isbn=&rft.btitle=&rft.title=BMC+Infectious+Diseases&rft.issn=14712334&rft_id=info:doi/10.1186%2F1471-2334-14-480 L2 - http://www.biomedcentral.com/1471-2334/14/480 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Number of references - 131 N1 - Last updated - 2014-12-11 N1 - SubjectsTermNotLitGenreText - Influenza; pandemics; Epidemics; Literature reviews; Influenza A; Reproduction; Waves; Infection; Mitigation; Sulfur dioxide; Infectious diseases; Reviews; Viruses; Outbreaks; Seasonal variations DO - http://dx.doi.org/10.1186/1471-2334-14-480 ER - TY - JOUR T1 - Genetic sequence analysis of circumsporozoite protein of Plasmodium vivax from Henan Province AN - 1560115385; 20468930 AB - Aim: To explore circumsporozoite protein (CSP) genotypes structure of Plasmodium vivax (P. vivax) in Henan. Methods: Blood samples of 34 malaria patients from Henan Province in 2011 were collected to extract DNA, and amplified using nested PCR technique, and the product was sequenced and analyzed. Results: The results showed that the 24 specimens from Henan indigenous cases all belonged to PV-I ; amino acid homology analysis showed that the specimens could be divided into two genotypes: A and B, the sequence of type A showed 90.6% - 94.2% homology to VK210, while type B showed 71.6%. Conclusion: The P. vivax CSP genotype of Henan all belongs to PV-I, and it can be further divided into two genotypes, which is significantly different from other countries. JF - Zhengzhou Daxue Xuebao (Yixue Ban) - Journal of Zhengzhou University. Medical sciences AU - LIU, Ying AU - ZHOU, Ruimin AU - ZHAO, Yuling AU - ZHAO, Xudong AU - XU, Bianli AU - ZHANG, Hongwei AD - Parasite Disease Institute, Center for Disease Control and Prevention of Henan Province, Zhengzhou 450016 Y1 - 2014///0, PY - 2014 DA - 0, 2014 SP - 308 EP - 311 PB - Zhengzhou Daxue VL - 49 IS - 3 SN - 1671-6825, 1671-6825 KW - Genetics Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Henan KW - Plasmodium vivax KW - circumsporozoite protein KW - genotype KW - Molecular structure KW - Human diseases KW - Nucleotide sequence KW - Malaria KW - Genotypes KW - Public health KW - Homology KW - DNA KW - Polymerase chain reaction KW - Proteins KW - Amino acid sequence KW - Q1 08443:Population genetics KW - G 07880:Human Genetics KW - K 03400:Human Diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1560115385?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Zhengzhou+Daxue+Xuebao+%28Yixue+Ban%29+-+Journal+of+Zhengzhou+University.+Medical+sciences&rft.atitle=Genetic+sequence+analysis+of+circumsporozoite+protein+of+Plasmodium+vivax+from+Henan+Province&rft.au=LIU%2C+Ying%3BZHOU%2C+Ruimin%3BZHAO%2C+Yuling%3BZHAO%2C+Xudong%3BXU%2C+Bianli%3BZHANG%2C+Hongwei&rft.aulast=LIU&rft.aufirst=Ying&rft.date=2014-01-01&rft.volume=49&rft.issue=3&rft.spage=308&rft.isbn=&rft.btitle=&rft.title=Zhengzhou+Daxue+Xuebao+%28Yixue+Ban%29+-+Journal+of+Zhengzhou+University.+Medical+sciences&rft.issn=16716825&rft_id=info:doi/10.13705%2Fj.issn.1671-6825.2014.03.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Last updated - 2016-02-04 N1 - SubjectsTermNotLitGenreText - Molecular structure; Human diseases; Nucleotide sequence; DNA; Proteins; Malaria; Genotypes; Public health; Amino acid sequence; circumsporozoite protein; Homology; Polymerase chain reaction; Plasmodium vivax DO - http://dx.doi.org/10.13705/j.issn.1671-6825.2014.03.004 ER - TY - JOUR T1 - Improvements in pandemic preparedness in 8 Central American countries, 2008 - 2012 AN - 1534838184; 19926434 AB - Background: In view of ongoing pandemic threats such as the recent human cases of novel avian influenza A(H7N9) in China, it is important that all countries continue their preparedness efforts. Since 2006, Central American countries have received donor funding and technical assistance from the U.S. Centers for Disease Control and Prevention (CDC) to build and improve their capacity for influenza surveillance and pandemic preparedness. Our objective was to measure changes in pandemic preparedness in this region, and explore factors associated with these changes, using evaluations conducted between 2008 and 2012. Methods: Eight Central American countries scored their pandemic preparedness across 12 capabilities in 2008, 2010 and 2012, using a standardized tool developed by CDC. Scores were calculated by country and capability and compared between evaluation years using the Student's t-test and Wilcoxon Rank Sum test, respectively. Virological data reported to WHO were used to assess changes in testing capacity between evaluation years. Linear regression was used to examine associations between scores, donor funding, technical assistance and WHO reporting. Results: All countries improved their pandemic preparedness between 2008 and 2012 and seven made statistically significant gains (p < 0.05). Increases in median scores were observed for all 12 capabilities over the same period and were statistically significant for eight of these (p < 0.05): country planning, communications, routine influenza surveillance, national respiratory disease surveillance, outbreak response, resources for containment, community interventions and health sector response. We found a positive association between preparedness scores and cumulative funding between 2006 and 2011 (R super(2) = 0.5, p < 0.01). The number of specimens reported to WHO from participating countries increased significantly from 5,551 (2008) to 18,172 (2012) (p < 0.01). Conclusions: Central America has made significant improvements in influenza pandemic preparedness between 2008 and 2012. U.S. donor funding and technical assistance provided to the region is likely to have contributed to the improvements we observed, although information on other sources of funding and support was unavailable to study. Gains are also likely the result of countries' response to the 2009 influenza pandemic. Further research is required to determine the degree to which pandemic improvements are sustainable. JF - BMC Health Services Research AU - Johnson, Lucinda EA AU - Clara, Wilfrido AU - Gambhir, Manoj AU - Fuentes, Rafael Chacon- AU - Marin-Correa, Carlos AU - Jara, Jorge AU - Minaya, Percy AU - Rodriguez, David AU - Blanco, Natalia AU - Iihoshi, Naomi AU - Orozco, Maribel AU - Lange, Carmen AU - Perez, Sergio Vinicio AU - Amador, Nydia AU - Widdowson, Marc-Alain AU - Moen, Ann C AU - Azziz-Baumgartner, Eduardo AD - Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA Y1 - 2014 PY - 2014 DA - 2014 SP - 209 PB - BioMed Central Ltd., Middlesex House London W1T 4LB United Kingdom VL - 14 IS - 1 SN - 1472-6963, 1472-6963 KW - Sustainability Science Abstracts; Health & Safety Science Abstracts KW - Disease control KW - Intervention KW - Sustainable development KW - Respiratory diseases KW - Influenza KW - USA KW - Prevention KW - Communications KW - Technical assistance KW - Standards KW - China, People's Rep. KW - Outbreaks KW - Containment KW - Central America KW - M3 1010:Issues in Sustainable Development KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1534838184?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=BMC+Health+Services+Research&rft.atitle=Improvements+in+pandemic+preparedness+in+8+Central+American+countries%2C+2008+-+2012&rft.au=Johnson%2C+Lucinda+EA%3BClara%2C+Wilfrido%3BGambhir%2C+Manoj%3BFuentes%2C+Rafael+Chacon-%3BMarin-Correa%2C+Carlos%3BJara%2C+Jorge%3BMinaya%2C+Percy%3BRodriguez%2C+David%3BBlanco%2C+Natalia%3BIihoshi%2C+Naomi%3BOrozco%2C+Maribel%3BLange%2C+Carmen%3BPerez%2C+Sergio+Vinicio%3BAmador%2C+Nydia%3BWiddowson%2C+Marc-Alain%3BMoen%2C+Ann+C%3BAzziz-Baumgartner%2C+Eduardo&rft.aulast=Johnson&rft.aufirst=Lucinda&rft.date=2014-01-01&rft.volume=14&rft.issue=1&rft.spage=209&rft.isbn=&rft.btitle=&rft.title=BMC+Health+Services+Research&rft.issn=14726963&rft_id=info:doi/10.1186%2F1472-6963-14-209 L2 - http://www.biomedcentral.com/1472-6963/14/209 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-06-01 N1 - Number of references - 10 N1 - Last updated - 2014-08-07 N1 - SubjectsTermNotLitGenreText - Influenza; Prevention; Communications; Technical assistance; Disease control; Sustainable development; Intervention; Standards; Outbreaks; Respiratory diseases; Containment; USA; China, People's Rep.; Central America DO - http://dx.doi.org/10.1186/1472-6963-14-209 ER - TY - JOUR T1 - Racial and Ethnic Differences in Obesity and Overweight as Predictors of the Onset of Functional Impairment AN - 1500785918; 19036277 AB - To examine racial and ethnic differences in the effects of body mass index (BMI) on the onset of functional impairment over 10 years of follow-up. Longitudinal analyses of a cohort from a nationally representative survey of community-dwelling American adults. Six waves (1996-2006) of the Health and Retirement Study (HRS). Two groups of HRS participants aged 50 and older without functional impairment at baseline (1996): 5,884 with no mobility difficulty and 8,484 with no activity of daily living (ADL) difficulty. Mobility difficulty was a composite measure of difficulty walking several blocks, walking one block, climbing several flights of stairs, and climbing one flight of stairs. ADL difficulty was measured as difficulty in dressing, bathing or showering, eating, and getting in and out of bed without help. The association between baseline BMI and risk of developing functional impairment was estimated using generalized estimating equation models. Overweight and obesity were significant predictors of functional impairment. Overweight and obese Hispanics were 41% and 91% more likely, respectively, to develop ADL disability than whites in the same BMI categories. Overweight and severely obese blacks were also more likely than their white counterparts to develop ADL disability. Risk of developing ADL difficulty was higher for Hispanics than for blacks in the obese category. No significant differences in onset of mobility difficulty were found between racial or ethnic groups within any BMI category. Blacks and Hispanics were at higher risk than whites of ADL but not mobility impairment. In addition to weight control, prevention efforts should promote exercise to reduce functional impairment, especially for blacks and Hispanics, who are at higher risk. JF - Journal of the American Geriatrics Society AU - Wei, Liang AU - Wu, Bei AD - Division of Chronic Disease Prevention. Shenyang Municipal Center for Disease Control and Prevention Y1 - 2014/01// PY - 2014 DA - Jan 2014 SP - 61 EP - 70 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 62 IS - 1 SN - 0002-8614, 0002-8614 KW - Risk Abstracts KW - Obesity KW - Prevention KW - Mobility KW - Disabilities KW - Body mass KW - Ethnic groups KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1500785918?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+American+Geriatrics+Society&rft.atitle=Racial+and+Ethnic+Differences+in+Obesity+and+Overweight+as+Predictors+of+the+Onset+of+Functional+Impairment&rft.au=Wei%2C+Liang%3BWu%2C+Bei&rft.aulast=Wei&rft.aufirst=Liang&rft.date=2014-01-01&rft.volume=62&rft.issue=1&rft.spage=61&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+American+Geriatrics+Society&rft.issn=00028614&rft_id=info:doi/10.1111%2Fjgs.12605 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-02-01 N1 - Last updated - 2014-06-12 N1 - SubjectsTermNotLitGenreText - Obesity; Prevention; Mobility; Body mass; Disabilities; Ethnic groups DO - http://dx.doi.org/10.1111/jgs.12605 ER - TY - JOUR T1 - Typology of older female sex workers and sexual risk for HIV infection in China: a qualitative study AN - 1496960004; 4521663 AB - The HIV epidemic continues to develop among older adults in China, including older female sex workers. Yet, few studies have been conducted among this relatively hidden population. The objectives of this study were to investigate the reasons for women's entry into sex work during their 30s and to develop typology of older women sex workers. Semi-structured in-depth interviews were conducted with 63 older women sex workers and six focus-group interviews with stakeholders in three cities in China in 2012. Data were analysed inductively using constant comparative method. The mean age of participants was 43 years and the mean age of entry into sex work was 39 years. The primary reasons for entry into sex work included heavy economic burdens, limited employment opportunities and the appealing nature of sex work. Street-based and venue- based older sex workers were identified based on where they solicited clients. Street- based older sex workers were more likely to engage in unsafe commercial sex due to financial incentives, whereas those in entertainment venues were unlikely to use condoms with regular clients. The development of effective HIV interventions needs to consider older women sex worker's unique characteristics and target factors that impede safer-sex practices. //ABSTRACT IN SPANISH: La epidemia del virus del sida sigue desarrollándose entre adultos mayores en China, incluyendo a trabajadoras sexuales de edad avanzada. Sin embargo, se han llevado a cabo pocos estudios sobre esta población relativamente oculta. El objetivo de este estudio era investigar por qué motivos las mujeres se introducían en el mundo del trabajo sexual en la treintena, y desarrollar la tipología de las trabajadores sexuales más mayores. En 2012 se llevaron a cabo entrevistas exhaustivas semiestructuradas con sesenta y tres trabajadoras sexuales mayores y seis entrevistas mediante charlas en grupo con personas afectadas en tres ciudades en China. Se analizaron los datos mediante un enfoque inductivo utilizando un método comparativo constante. Las participantes tenían una edad media de 43 años y de promedio se habían introducido en el mundo del trabajo sexual a los 39 años. Los problemas económicos considerables, las oportunidades limitadas de empleo y la naturaleza atractiva del trabajo sexual fueron algunos de los motivos principales de introducirse en el mundo del trabajo sexual. Se distinguía entre trabajadoras sexuales mayores que ejercían en la calle o en locales, en función de dónde buscaban a sus clientes. Las trabajadoras sexuales mayores que ejercían en la calle solían tener más relaciones sexuales poco seguras debido a los incentivos financieros, y las que ejercían en locales era poco probable que utilizaran preservativos con clientes regulares. En el desarrollo de programas eficaces contra el VIH, es necesario tener en cuenta las características peculiares de las trabajadoras sexuales mayores y analizar qué factores impiden prácticas sexuales más seguras. //ABSTRACT IN FRENCH: L'épidémie de VIH continue de s'étendre parmi les adultes âgés en Chine, y compris les femmes qui exercent le travail du sexe. Pourtant peu d'études ont été conduites dans cette population relativement >. Cette étude avait pour objectifs d'examiner les raisons pour lesquelles les femmes s'engagent dans le travail du sexe vers l'âge de trente ans et de développer une typologie des travailleuses du sexe âgées. Des entretiens semi-structurés avec soixante-trois travailleuses du sexe âgées et six groupes de discussion thématique avec différentes personnes concernées ont été conduits dans trois villes chinoises en 2012. Les données ont été analysées de manière inductive avec une méthode de comparaison constante. L'âge moyen des participant(e)s était de 43 ans; et de 39 ans pour les débuts dans le travail du sexe. Les principales causes de l'engagement dans le travail du sexe incluent les charges économiques trop lourdes, les opportunités d'emploi limitées et le caractère attrayant de ce métier. Les travailleuses du sexe âgées basées dans la rue et celles basées dans des établissements de loisirs ont été catégorisées en fonction du lieu ou elles sollicitaient leurs clients. L'étude révèle que travailleuses du sexe âgées qui exercent dans la rue ont une plus forte tendance à s'engager dans des rapports sexuels non protégés en raison des incitations financières, alors que celles qui exercent dans des lieux de divertissement ont une moindre tendance à utiliser des préservatifs avec leurs clients réguliers. L'élaboration de programmes pertinents de prévention du VIH doit être fondée sur la prise en compte des caractéristiques spécifiques aux travailleuses du sexe âgées en ciblant les facteurs qui entravent leurs pratiques du sexe à moindre risque. Reprinted by permission of Taylor & Francis Ltd JF - Culture, health and sexuality AU - Hao, Chun AU - Liu, Hongjie AU - Sherman, Susan G AU - Jiang, Baofa AU - Li, Xiaojing AU - Xu, Yongfang AU - Jiang, Zhenxia AU - Zang, Chunpeng AD - University of Maryland, College Park ; Shandong University ; Hefei Center for Disease Control and Prevention ; Nanning Center for Disease Control and Prevention ; Qingdao Center for Disease Control and Prevention Y1 - 2014/01// PY - 2014 DA - Jan 2014 SP - 47 EP - 60 VL - 16 IS - 1 SN - 1369-1058, 1369-1058 KW - Anthropology KW - Risk KW - Sex workers KW - Typology KW - Typological analysis KW - Women KW - Prostitution KW - HIV KW - China KW - Sexually transmitted diseases KW - Older workers UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1496960004?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Culture%2C+health+and+sexuality&rft.atitle=Typology+of+older+female+sex+workers+and+sexual+risk+for+HIV+infection+in+China%3A+a+qualitative+study&rft.au=Hao%2C+Chun%3BLiu%2C+Hongjie%3BSherman%2C+Susan+G%3BJiang%2C+Baofa%3BLi%2C+Xiaojing%3BXu%2C+Yongfang%3BJiang%2C+Zhenxia%3BZang%2C+Chunpeng&rft.aulast=Hao&rft.aufirst=Chun&rft.date=2014-01-01&rft.volume=16&rft.issue=1&rft.spage=47&rft.isbn=&rft.btitle=&rft.title=Culture%2C+health+and+sexuality&rft.issn=13691058&rft_id=info:doi/10.1080%2F13691058.2013.826820 LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2014-01-23 N1 - Last updated - 2014-02-11 N1 - SubjectsTermNotLitGenreText - 13039 971; 13041 2688 2449 10404; 8920 13682; 11556 13682; 13598 5421 6091; 10359 11556 13682; 11035; 5703 3617 6220; 11581 3617 6220; 93 116 30 DO - http://dx.doi.org/10.1080/13691058.2013.826820 ER - TY - JOUR T1 - Cytomegalovirus Survival and Transferability and the Effectiveness of Common Hand-Washing Agents against Cytomegalovirus on Live Human Hands AN - 1492660451; 18996687 AB - Congenital cytomegalovirus (CMV) transmission can occur when women acquire CMV while pregnant. Infection control guidelines may reduce risk for transmission. We studied the duration of CMV survival after application of bacteria to the hands and after transfer from the hands to surfaces and the effectiveness of cleansing with water, regular and antibacterial soaps, sanitizer, and diaper wipes. Experiments used CMV AD169 in saliva at initial titers of 1 105 infectious particles/ml. Samples from hands or surfaces (points between 0 and 15 min) were placed in culture and observed for at least 2 weeks. Samples were also tested using CMV real-time PCR. After application of bacteria to the hands, viable CMV was recovered from 17/20 swabs at 0 min, 18/20 swabs at 1 min, 5/20 swabs at 5 min, and 4/20 swabs at 15 min. After transfer, duration of survival was at least 15 min on plastic (1/2 swabs), 5 min on crackers and glass (3/4 swabs), and 1 min or less on metal and cloth (3/4 swabs); no viable virus was collected from wood, rubber, or hands. After cleansing, no viable virus was recovered using water (0/22), plain soap (0/20), antibacterial soap (0/20), or sanitizer (0/22). Viable CMV was recovered from 4/20 hands 10 min after diaper wipe cleansing. CMV remains viable on hands for sufficient times to allow transmission. CMV may be transferred to surfaces with reduced viability. Hand-cleansing methods were effective at eliminating viable CMV from hands. JF - Applied and Environmental Microbiology AU - Stowell, Jennifer D AU - Forlin-Passoni, Daniela AU - Radford, Kay AU - Bate, Sheri L AU - Dollard, Sheila C AU - Bialek, Stephanie R AU - Cannon, Michael J AU - Schmid, D Scott AD - Centers for Disease Control and Prevention, National Center on Birth Defects and Developmental Disabilities, Atlanta, Georgia, USA, SSchmid@cdc.gov. Y1 - 2014/01// PY - 2014 DA - Jan 2014 SP - 455 EP - 461 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 80 IS - 2 SN - 0099-2240, 0099-2240 KW - Virology & AIDS Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Disease transmission KW - Hand KW - Cytomegalovirus KW - V:22400 KW - A:01340 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1492660451?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Cytomegalovirus+Survival+and+Transferability+and+the+Effectiveness+of+Common+Hand-Washing+Agents+against+Cytomegalovirus+on+Live+Human+Hands&rft.au=Stowell%2C+Jennifer+D%3BForlin-Passoni%2C+Daniela%3BRadford%2C+Kay%3BBate%2C+Sheri+L%3BDollard%2C+Sheila+C%3BBialek%2C+Stephanie+R%3BCannon%2C+Michael+J%3BSchmid%2C+D+Scott&rft.aulast=Stowell&rft.aufirst=Jennifer&rft.date=2014-01-01&rft.volume=80&rft.issue=2&rft.spage=455&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/10.1128%2FAEM.03262-13 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-01-01 N1 - Number of references - 1 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Hand; Cytomegalovirus DO - http://dx.doi.org/10.1128/AEM.03262-13 ER - TY - JOUR T1 - Diarrheal Illness Among US Residents Providing Medical Services in Haiti During the Cholera Epidemic, 2010 to 2011 AN - 1492638629; 18988849 AB - Although nosocomial transmission of cholera is rare, two US healthcare workers (HCW) became ill with cholera after providing medical services during the Haiti cholera epidemic. To assess the incidence of diarrheal illness and explore preventive health behaviors practiced by US residents who provided medical services in Haiti, we conducted a cross-sectional, anonymous, web-based survey. We e-mailed 896 participants from 50 US-based, health-focused non-governmental organizations (NGOs), of whom 381 (43%) completed the survey. Fifty-six percent of respondents (n = 215) reported providing some care for patients with cholera. Diarrhea was reported by 31 (8%) respondents. One person was diagnosed with cholera by serologic testing. NGOs responding to international emergencies should ensure ample access to basic hygiene supplies and should promote their use to reduce the incidence of diarrheal illness among HCW working overseas. JF - Journal of Travel Medicine AU - Schilling, Katharine A AU - Cartwright, Emily J AU - Stamper, John AU - Locke, Michael AU - Esposito, Douglas H AU - Balaban, Victor AU - Mintz, Eric AD - Division of Foodborne, Waterborne, and Environmental Diseases, Waterborne Disease Prevention Branch, National Center for Emerging and Zoonotic Infectious Diseases. US Centers for Disease Control and Prevention Y1 - 2014/01// PY - 2014 DA - January 2014 SP - 55 EP - 57 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 21 IS - 1 SN - 1195-1982, 1195-1982 KW - Microbiology Abstracts B: Bacteriology; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Health & Safety Science Abstracts KW - Travel KW - Diarrhea KW - Epidemics KW - Pathogenic bacteria KW - Bacterial diseases KW - Medical personnel KW - USA KW - Non-governmental organizations KW - Nosocomial infection KW - Emergencies KW - Cholera KW - Hygiene KW - ASW, Caribbean Sea, Greater Antilles, Haiti KW - Nongovernmental organizations KW - Hospitals KW - Q1 08484:Species interactions: parasites and diseases KW - J 02400:Human Diseases KW - H 1000:Occupational Safety and Health KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1492638629?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Travel+Medicine&rft.atitle=Diarrheal+Illness+Among+US+Residents+Providing+Medical+Services+in+Haiti+During+the+Cholera+Epidemic%2C+2010+to+2011&rft.au=Schilling%2C+Katharine+A%3BCartwright%2C+Emily+J%3BStamper%2C+John%3BLocke%2C+Michael%3BEsposito%2C+Douglas+H%3BBalaban%2C+Victor%3BMintz%2C+Eric&rft.aulast=Schilling&rft.aufirst=Katharine&rft.date=2014-01-01&rft.volume=21&rft.issue=1&rft.spage=55&rft.isbn=&rft.btitle=&rft.title=Journal+of+Travel+Medicine&rft.issn=11951982&rft_id=info:doi/10.1111%2Fjtm.12075 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-01-01 N1 - Number of references - 9 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Epidemics; Pathogenic bacteria; Bacterial diseases; Emergencies; Hygiene; Travel; Diarrhea; Non-governmental organizations; Cholera; Medical personnel; Hospitals; Nosocomial infection; Nongovernmental organizations; USA; ASW, Caribbean Sea, Greater Antilles, Haiti DO - http://dx.doi.org/10.1111/jtm.12075 ER - TY - JOUR T1 - The substantial hospitalization burden of influenza in central China: surveillance for severe, acute respiratory infection, and influenza viruses, 2010-2012 AN - 1492636862; 18969010 AB - Published data on influenza in severe acute respiratory infection (SARI) patients are limited. We conducted SARI surveillance in central China and estimated hospitalization rates of SARI attributable to influenza by viral type/subtype. Surveillance was conducted at four hospitals in Jingzhou, China from 2010 to 2012. We enrolled hospitalized patients who had temperature greater than or equal to 37.3 degree C and at least one of: cough, sore throat, tachypnea, difficulty breathing, abnormal breath sounds on auscultation, sputum production, hemoptysis, chest pain, or chest radiograph consistent with pneumonia. A nasopharyngeal swab was collected from each case-patient within 24 hours of admission for influenza testing by real-time reverse transcription PCR. Of 17 172 SARI patients enrolled, 90% were aged <15 years. The median duration of hospitalization was 5 days. Of 16 208 (94%) SARI cases tested, 2057 (13%) had confirmed influenza, including 1427 (69%) aged <5 years. Multiple peaks of influenza occurred during summer, winter, and spring months. Influenza was associated with an estimated 115 and 142 SARI hospitalizations per 100 000 during 2010-2011 and 2011-2012 [including A(H3N2): 55 and 44 SARI hospitalizations per 100 000; pandemic A(H1N1): 33 SARI hospitalizations per 100 000 during 2010-2011; influenza B: 26 and 98 hospitalizations per 100 000], with the highest rate among children aged 6-11 months (3603 and 3805 hospitalizations per 100 000 during 2010-2011 and 2011-2012, respectively). In central China, influenza A and B caused a substantial number of hospitalizations during multiple periods each year. Our findings strongly suggest that young children should be the highest priority group for annual influenza vaccination in China. JF - Influenza and Other Respiratory Viruses AU - Yu, Hongjie AU - Huang, Jigui AU - Huai, Yang AU - Guan, Xuhua AU - Klena, John AU - Liu, Shali AU - Peng, Youxing AU - Yang, Hui AU - Luo, Jun AU - Zheng, Jiandong AU - Chen, Maoyi AU - Peng, Zhibin AU - Xiang, Nijuan AU - Huo, Xixiang AU - Xiao, Lin AU - Jiang, Hui AU - Chen, Hui AU - Zhang, Yuzhi AU - Xing, Xuesen AU - Xu, Zhen AU - Feng, Zijian AU - Zhan, Faxian AU - Yang, Weizhong AU - Uyeki, Timothy M AU - Wang, Yu AU - Varma, Jay K AD - Divison of Infectious Disease. Chinese Center for Disease Control and Prevention Y1 - 2014/01// PY - 2014 DA - Jan 2014 SP - 53 EP - 65 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 8 IS - 1 SN - 1750-2640, 1750-2640 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Influenza B KW - Influenza A KW - Respiration KW - Viruses KW - Summer KW - Pain KW - Chest KW - Infection KW - Winter KW - Reverse transcription KW - Influenza KW - pandemics KW - Sound KW - Polymerase chain reaction KW - Temperature effects KW - Data processing KW - Temperature KW - Cough KW - Pharyngitis KW - Hemoptysis KW - Children KW - Vaccination KW - Priorities KW - China, People's Rep. KW - Vaccines KW - Sputum KW - Radiography KW - Pneumonia KW - Hospitals KW - H 1000:Occupational Safety and Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1492636862?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Influenza+and+Other+Respiratory+Viruses&rft.atitle=The+substantial+hospitalization+burden+of+influenza+in+central+China%3A+surveillance+for+severe%2C+acute+respiratory+infection%2C+and+influenza+viruses%2C+2010-2012&rft.au=Yu%2C+Hongjie%3BHuang%2C+Jigui%3BHuai%2C+Yang%3BGuan%2C+Xuhua%3BKlena%2C+John%3BLiu%2C+Shali%3BPeng%2C+Youxing%3BYang%2C+Hui%3BLuo%2C+Jun%3BZheng%2C+Jiandong%3BChen%2C+Maoyi%3BPeng%2C+Zhibin%3BXiang%2C+Nijuan%3BHuo%2C+Xixiang%3BXiao%2C+Lin%3BJiang%2C+Hui%3BChen%2C+Hui%3BZhang%2C+Yuzhi%3BXing%2C+Xuesen%3BXu%2C+Zhen%3BFeng%2C+Zijian%3BZhan%2C+Faxian%3BYang%2C+Weizhong%3BUyeki%2C+Timothy+M%3BWang%2C+Yu%3BVarma%2C+Jay+K&rft.aulast=Yu&rft.aufirst=Hongjie&rft.date=2014-01-01&rft.volume=8&rft.issue=1&rft.spage=53&rft.isbn=&rft.btitle=&rft.title=Influenza+and+Other+Respiratory+Viruses&rft.issn=17502640&rft_id=info:doi/10.1111%2Firv.12205 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-01-01 N1 - Last updated - 2014-05-02 N1 - SubjectsTermNotLitGenreText - Temperature effects; Influenza B; Data processing; Respiration; Influenza A; Cough; Pain; Pharyngitis; Infection; Children; Chest; Hemoptysis; Vaccination; Reverse transcription; pandemics; Sound; Polymerase chain reaction; Radiography; Sputum; Pneumonia; Hospitals; Influenza; Viruses; Temperature; Priorities; Summer; Vaccines; Winter; China, People's Rep. DO - http://dx.doi.org/10.1111/irv.12205 ER - TY - JOUR T1 - The Global Availability of Rabies Immune Globulin and Rabies Vaccine in Clinics Providing Indirect Care to Travelers AN - 1492617344; 18988841 AB - We assessed rabies vaccine (RV) and immune globulin (RIG) availability on the local market by querying US Embassy medical staff worldwide. Of 112 responses, 23% were from West, Central, and East Africa. RV and RIG availability varied by region. Possible rabies exposures accounted for 2% of all travelers' health inquiries. JF - Journal of Travel Medicine AU - Jentes, Emily S AU - Blanton, Jesse D AU - Johnson, Katherine J AU - Petersen, Brett W AU - Lamias, Mark J AU - Robertson, Kis AU - Franka, Richard AU - Muhm, Daniel AU - Rupprecht, Charles E AU - Marano, Nina AU - Brunette, Gary W AD - Division of Global Migration and Quarantine, National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA Y1 - 2014/01// PY - 2014 DA - Jan 2014 SP - 62 EP - 66 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 21 IS - 1 SN - 1195-1982, 1195-1982 KW - Immunology Abstracts; Virology & AIDS Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources KW - Travel KW - Rabies KW - Disease control KW - Africa KW - Globulins KW - Vaccines KW - Immunoglobulins KW - F 06905:Vaccines KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1492617344?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Travel+Medicine&rft.atitle=The+Global+Availability+of+Rabies+Immune+Globulin+and+Rabies+Vaccine+in+Clinics+Providing+Indirect+Care+to+Travelers&rft.au=Jentes%2C+Emily+S%3BBlanton%2C+Jesse+D%3BJohnson%2C+Katherine+J%3BPetersen%2C+Brett+W%3BLamias%2C+Mark+J%3BRobertson%2C+Kis%3BFranka%2C+Richard%3BMuhm%2C+Daniel%3BRupprecht%2C+Charles+E%3BMarano%2C+Nina%3BBrunette%2C+Gary+W&rft.aulast=Jentes&rft.aufirst=Emily&rft.date=2014-01-01&rft.volume=21&rft.issue=1&rft.spage=62&rft.isbn=&rft.btitle=&rft.title=Journal+of+Travel+Medicine&rft.issn=11951982&rft_id=info:doi/10.1111%2Fjtm.12085 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-01-01 N1 - Number of references - 7 N1 - Last updated - 2015-04-16 N1 - SubjectsTermNotLitGenreText - Disease control; Globulins; Vaccines; Travel; Rabies; Immunoglobulins; Africa DO - http://dx.doi.org/10.1111/jtm.12085 ER - TY - JOUR T1 - Respiratory Syncytial Virus Circulation in Seven Countries With Global Disease Detection Regional Centers AN - 1639992880; 20900322 AB - Background. Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infections in young children globally, with the highest burden in low- and middle-income countries where the association between RSV activity and climate remains unclear. Methods. Monthly laboratory-confirmed RSV cases and associations with climate data were assessed for respiratory surveillance sites in tropical and subtropical areas (Bangladesh, China, Egypt, Guatemala, Kenya, South Africa, and Thailand) during 2004-2012. Average monthly minimum and maximum temperatures, relative humidity, and precipitation were calculated using daily local weather data from the US National Climatic Data Center. Results. RSV circulated with 1-2 epidemic periods each year in site areas. RSV seasonal timing and duration were generally consistent within country from year to year. Associations between RSV and weather varied across years and geographic locations. RSV usually peaked in climates with high annual precipitation (Bangladesh, Guatemala, and Thailand) during wet months, whereas RSV peaked during cooler months in moderately hot (China) and arid (Egypt) regions. In South Africa, RSV peaked in autumn, whereas no associations with seasonal weather trends were observed in Kenya. Conclusions. Further understanding of RSV seasonality in developing countries and various climate regions will be important to better understand the epidemiology of RSV and for timing the use of future RSV vaccines and immunoprophylaxis in low- and middle-income countries. JF - Journal of Infectious Diseases AU - Haynes, Amber K AU - Manangan, Arie P AU - Iwane, Marika K AU - Sturm-Ramirez, Katharine AU - Homaira, Nusrat AU - Abdullah Brooks, W AU - Luby, Stephen AU - Rahman, Mahmudur AU - Klena, John D AU - Zhang, Yuzhi AD - Division of Viral Diseases, National Center for Immunizations and Respiratory Diseases; Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases, 1600 Clifton Rd NE, MS A-34, Atlanta, GA 30333, ahaynes1@cdc.gov Y1 - 2013/12/15/ PY - 2013 DA - 2013 Dec 15 SP - S246 EP - S254 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 208 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Water Resources Abstracts; Aqualine Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 2: Ocean Technology Policy & Non-Living Resources KW - respiratory tract infections KW - respiratory syncytial virus infections KW - climate KW - seasons KW - humans KW - Relative humidity KW - Thailand KW - Infectious diseases KW - Diseases KW - Hydrologic Data KW - Seasonal variations KW - Bangladesh KW - Timing KW - Weather KW - Epidemics KW - Respiratory syncytial virus KW - Epidemiology KW - Vaccines KW - Developing countries KW - Metabolism KW - Egypt, Arab Rep. KW - Immunoprophylaxis KW - Respiration KW - Infection KW - Relative Humidity KW - Climatic data KW - Kenya KW - South Africa KW - Disease detection KW - Temperature effects KW - Data processing KW - Guatemala KW - Climates KW - Climate KW - Precipitation KW - Children KW - Respiratory tract diseases KW - Developing Countries KW - China, People's Rep. KW - Q2 09243:Structure, mechanics and thermodynamics KW - SW 5010:Network design KW - AQ 00008:Effects of Pollution KW - Q5 08502:Methods and instruments KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1639992880?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Respiratory+Syncytial+Virus+Circulation+in+Seven+Countries+With+Global+Disease+Detection+Regional+Centers&rft.au=Haynes%2C+Amber+K%3BManangan%2C+Arie+P%3BIwane%2C+Marika+K%3BSturm-Ramirez%2C+Katharine%3BHomaira%2C+Nusrat%3BAbdullah+Brooks%2C+W%3BLuby%2C+Stephen%3BRahman%2C+Mahmudur%3BKlena%2C+John+D%3BZhang%2C+Yuzhi&rft.aulast=Haynes&rft.aufirst=Amber&rft.date=2013-12-15&rft.volume=208&rft.issue=&rft.spage=S246&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjit515 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-12-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Climatic data; Relative humidity; Epidemics; Infectious diseases; Respiration; Climate; Disease detection; Vaccines; Metabolism; Temperature effects; Weather; Data processing; Immunoprophylaxis; Precipitation; Children; Infection; Respiratory tract diseases; Epidemiology; Developing countries; Seasonal variations; Timing; Climates; Developing Countries; Diseases; Hydrologic Data; Relative Humidity; Respiratory syncytial virus; Egypt, Arab Rep.; Kenya; Thailand; Guatemala; South Africa; China, People's Rep.; Bangladesh DO - http://dx.doi.org/10.1093/infdis/jit515 ER - TY - JOUR T1 - Progress and Challenges in RSV Prophylaxis and Vaccine Development AN - 1622610308; 20900314 AB - Respiratory syncytial virus (RSV) is a respiratory tract pathogen that causes significant morbidity and mortality in children aged <5 years (most disease occurs at age <1 year) and is a major public health burden worldwide. More than 90% of children are infected at least once with RSV before the age of 2 years [1-3]. RSV accounts for approximately 70% of hospitalizations due to bronchiolitis [1,4], In the United States alone, the estimated healthcare costs associated with RSV hospitalizations exceed $950 million, making it a significant economic burden [5]. Further, the RSV burden is disproportionately greater in children aged <5 years living in developing countries [3]. RSV infection does not confer long-term protection, as reinfections occur throughout life, which poses a significant disease risk in individuals with cardiopulmonary disease, immunocompromised patients, and the elderly [7]. In the elderly, complications of RSV infection often result from exacerbation of underlying pulmonary and cardiac disease. [7]. JF - Journal of Infectious Diseases AU - Haynes, Lia M AD - Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases, 1600 Clifton Rd. NE, A-34, Atlanta, GA 30333, loh5@cdc.gov Y1 - 2013/12/15/ PY - 2013 DA - 2013 Dec 15 SP - S177 EP - S183 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 208 SN - 0022-1899, 0022-1899 KW - Immunology Abstracts; Health & Safety Science Abstracts KW - Age KW - Elderly KW - Infection KW - Morbidity KW - Public health KW - Economics KW - Geriatrics KW - Heart diseases KW - Respiratory tract KW - Mortality KW - Complications KW - Lung diseases KW - Pathogens KW - Children KW - Respiratory syncytial virus KW - USA KW - Health care KW - Immunocompromised hosts KW - Prophylaxis KW - Vaccines KW - Developing countries KW - Bronchopneumonia KW - H 1000:Occupational Safety and Health KW - F 06910:Microorganisms & Parasites UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1622610308?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Progress+and+Challenges+in+RSV+Prophylaxis+and+Vaccine+Development&rft.au=Haynes%2C+Lia+M&rft.aulast=Haynes&rft.aufirst=Lia&rft.date=2013-12-15&rft.volume=208&rft.issue=&rft.spage=S177&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjit512 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-11-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Mortality; Age; Lung diseases; Pathogens; Children; Infection; Morbidity; Public health; Immunocompromised hosts; Economics; Geriatrics; Prophylaxis; Vaccines; Developing countries; Bronchopneumonia; Respiratory tract; Heart diseases; Complications; Elderly; Health care; Respiratory syncytial virus; USA DO - http://dx.doi.org/10.1093/infdis/jit512 ER - TY - JOUR T1 - Cost-effectiveness of administering 13-valent pneumococcal conjugate vaccine in addition to 23-valent pneumococcal polysaccharide vaccine to adults with immunocompromising conditions AN - 1505339671; 19336216 AB - In June, 2012 a single dose of 13-valent pneumococcal conjugate vaccine (PCV13) was added to the recommendation for immunocompromised adults who were previously recommended to receive only 23-valent pneumococcal polysaccharide vaccine (PPSV23). PCV13 may be more effective, though it covers fewer disease-causing strains. We examined the incremental cost-effectiveness of adding one dose of PCV13 to the pre-2012 recommendation of PPSV23 for adults with 4 immunocompromising conditions who are at increased risk of pneumococcal disease: HIV/AIDS, hematologic cancer, solid organ transplants, and end stage renal disease. We used a probabilistic model following a single cohort of 302,397 immunocompromised adults. We used vaccination coverage and disease incidence data specific to each immunocompromising condition. Assumptions about PPSV23 and PCV13 vaccine effectiveness were based on two randomized controlled trials and several observational studies conducted among HIV-infected adults. The addition of one dose of PCV13 to the previously recommended PPSV23 doses for adults with selected immunocompromised conditions potentially reduces both disease and costs. JF - Vaccine AU - Cho, Bo-Hyun AU - Stoecker, Charles AU - Link-Gelles, Ruth AU - Moore, Matthew R AD - National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States, cfstoecker@tulane.edu Y1 - 2013/12/05/ PY - 2013 DA - 2013 Dec 05 SP - 6011 EP - 6021 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 31 IS - 50 SN - 0264-410X, 0264-410X KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - PCV13 KW - Incremental cost-effectiveness KW - Immunocompromised adults KW - Streptococcus pneumoniae KW - Acquired immune deficiency syndrome KW - Data processing KW - Human immunodeficiency virus KW - Kidney transplantation KW - Kidney diseases KW - Vaccines KW - Polysaccharides KW - Vaccination KW - Cancer KW - Models KW - J 02350:Immunology KW - F 06920:Transplantation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1505339671?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Cost-effectiveness+of+administering+13-valent+pneumococcal+conjugate+vaccine+in+addition+to+23-valent+pneumococcal+polysaccharide+vaccine+to+adults+with+immunocompromising+conditions&rft.au=Cho%2C+Bo-Hyun%3BStoecker%2C+Charles%3BLink-Gelles%2C+Ruth%3BMoore%2C+Matthew+R&rft.aulast=Cho&rft.aufirst=Bo-Hyun&rft.date=2013-12-05&rft.volume=31&rft.issue=50&rft.spage=6011&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/10.1016%2Fj.vaccine.2013.10.024 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-03-01 N1 - Last updated - 2015-04-16 N1 - SubjectsTermNotLitGenreText - Acquired immune deficiency syndrome; Data processing; Kidney transplantation; Kidney diseases; Vaccines; Polysaccharides; Vaccination; Cancer; Models; Streptococcus pneumoniae; Human immunodeficiency virus DO - http://dx.doi.org/10.1016/j.vaccine.2013.10.024 ER - TY - JOUR T1 - The Reproductive Health Behaviors of HIV-Infected Young Women in the United States: A Literature Review AN - 1827930445; PQ0003646158 AB - HIV-infected young women in the United States have important reproductive health needs that are made more complex by their HIV status. We searched Pubmed and relevant bibliographies to identify 32 articles published from 2001 to July 2012 that described the prevalence, correlates, and characteristics of the sexual activity, relationships, pregnancy intentions, HIV status disclosure, and contraceptive and condom use among US HIV-infected adolescents and young women. Our synthesis of those articles found that, like youth not infected with HIV, substantial proportions of HIV-infected youth were sexually active, and most sought romantic or sexual relationships, though their serostatus may have affected the pace of physical and emotional intimacy. Disclosure was difficult, and large proportions of HIV-infected youth had not disclosed their serostatus to recent partners. A few studies suggest that most HIV-infected young women hoped to have children in the future, but many wanted to avoid pregnancy until later. Only one study described contraceptive use among this population in detail and found that condoms were a primary method of contraception. The results point to substantial gaps in published research, particularly in the areas of pregnancy intentions and contraceptive use. Much more needs to be done in research and health services to better understand and meet the complex health needs of HIV-infected young women. JF - AIDS Patient Care and STDs AU - Carter, Marion W AU - Kraft, Joan M AU - Hatfield-Timajchy, Kendra AU - Snead, Margaret C AU - Ozeryansky, Larisa AU - Fasula, Amy M AU - Koenig, Linda J AU - Kourtis, Athena P AD - Center for Disease Control and Prevention, Atlanta, Georgia. Y1 - 2013/12// PY - 2013 DA - December 2013 SP - 669 EP - 680 PB - Mary Ann Liebert, Inc., 2 Madison Ave Larchmont NY 10538 United States VL - 27 IS - 12 SN - 1087-2914, 1087-2914 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Emotions KW - Acquired immune deficiency syndrome KW - Retroviridae KW - Reproductive behavior KW - Condoms KW - Lentivirus KW - Sexually transmitted diseases KW - Adolescents KW - Contraceptives KW - Motivation KW - Adolescence KW - Children KW - Pregnancy KW - USA KW - Literature reviews KW - Contraception KW - Bibliographies KW - Reproduction KW - Females KW - V 22360:AIDS and HIV KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1827930445?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+Patient+Care+and+STDs&rft.atitle=The+Reproductive+Health+Behaviors+of+HIV-Infected+Young+Women+in+the+United+States%3A+A+Literature+Review&rft.au=Carter%2C+Marion+W%3BKraft%2C+Joan+M%3BHatfield-Timajchy%2C+Kendra%3BSnead%2C+Margaret+C%3BOzeryansky%2C+Larisa%3BFasula%2C+Amy+M%3BKoenig%2C+Linda+J%3BKourtis%2C+Athena+P&rft.aulast=Carter&rft.aufirst=Marion&rft.date=2013-12-01&rft.volume=27&rft.issue=12&rft.spage=669&rft.isbn=&rft.btitle=&rft.title=AIDS+Patient+Care+and+STDs&rft.issn=10872914&rft_id=info:doi/10.1089%2Fapc.2013.0208 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-10-01 N1 - Number of references - 71 N1 - Last updated - 2016-10-26 N1 - SubjectsTermNotLitGenreText - Condoms; Emotions; Contraception; Literature reviews; Motivation; Bibliographies; Adolescence; Reproductive behavior; Children; Contraceptives; Pregnancy; Acquired immune deficiency syndrome; Reproduction; Females; Adolescents; Sexually transmitted diseases; Lentivirus; Retroviridae; USA DO - http://dx.doi.org/10.1089/apc.2013.0208 ER - TY - JOUR T1 - Obesity Prevention in the Early Care and Education Setting: Successful Initiatives across a Spectrum of Opportunities AN - 1550994890; 2011-673392 AB - With an estimated 12.1% of children aged 2-5 years already obese, prevention efforts must target our youngest children. One of the best places to reach young children for such efforts is the early care and education setting (ECE). More than 11 million U.S. children spend an average of 30 hours per week in ECE facilities. Increased attention at the national, state, and community level on the ECE setting for early obesity prevention efforts has sparked a range of innovative efforts. To assist these efforts, CDC developed a technical assistance and training framework -- the Spectrum of Opportunities for Obesity Prevention in the ECE setting -- which also served as the organizing framework for the Weight of the Nation ECE track. Participants highlighted their efforts at national, state, and local levels pursuing opportunities on the Spectrum, the standards and best practices that had been the emphasis of their efforts, and common steps for developing, implementing, and evaluating initiatives. Strong leadership and collaboration among a broad group of stakeholders; systematic assessment of needs, opportunities and resources; funding sources; and training and professional development were reported to be integral for successful implementation of standards and best practices, and sustainability. Adapted from the source document. JF - The Journal of Law, Medicine & Ethics AU - Reynolds, Meredith A AU - Jackson Cotwright, Caree AU - Polhamus, Barbara AU - Gertel-Rosenberg, Allison AU - Chang, Debbie AD - National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention in Atlanta, GA. Y1 - 2013/12// PY - 2013 DA - December 2013 SP - 8 EP - 18 PB - Wiley-Blackwell, UK VL - 41 IS - s2 SN - 1073-1105, 1073-1105 KW - Population groups, population policy, and demographics - Children and youth KW - Health conditions and policy - Diseases and disorders KW - Education and education policy - Education KW - Government - Local and municipal government KW - International relations - International relief and humanitarian assistance KW - Politics - Politics and policy-making KW - Government - State or regional government KW - Obesity KW - Education KW - State government KW - Local government KW - Technical assistance KW - Standards KW - Children KW - Leadership KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1550994890?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+Law%2C+Medicine+%26+Ethics&rft.atitle=Obesity+Prevention+in+the+Early+Care+and+Education+Setting%3A+Successful+Initiatives+across+a+Spectrum+of+Opportunities&rft.au=Reynolds%2C+Meredith+A%3BJackson+Cotwright%2C+Caree%3BPolhamus%2C+Barbara%3BGertel-Rosenberg%2C+Allison%3BChang%2C+Debbie&rft.aulast=Reynolds&rft.aufirst=Meredith&rft.date=2013-12-01&rft.volume=41&rft.issue=s2&rft.spage=8&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+Law%2C+Medicine+%26+Ethics&rft.issn=10731105&rft_id=info:doi/10.1111%2Fjlme.12104 LA - English DB - PAIS Index N1 - Date revised - 2014-08-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Children; Obesity; Standards; Education; Local government; Technical assistance; Leadership; State government DO - http://dx.doi.org/10.1111/jlme.12104 ER - TY - JOUR T1 - Cell Culture-Selected Substitutions in Influenza A(H3N2) Neuraminidase Affect Drug Susceptibility Assessment AN - 1464504642; 18808483 AB - Assessment of drug susceptibility has become an integral part of influenza virus surveillance. In this study, we describe the drug resistance profile of influenza A(H3N2) virus, A/Mississippi/05/2011, collected from a patient treated with oseltamivir and detected via surveillance. An MDCK cell-grown isolate of this virus exhibited highly reduced inhibition by the neuraminidase (NA) inhibitors (NAIs) oseltamivir (8,005-fold), zanamivir (813-fold), peramivir (116-fold), and laninamivir (257-fold) in the NA inhibition assay. Sequence analysis of its NA gene revealed a known oseltamivir-resistance marker, the glutamic acid-to-valine substitution at position 119 (E119V), and an additional change, threonine to isoleucine at position 148 (T148I). Unlike E119V, T148I was not detected in the clinical sample but acquired during viral propagation in MDCK cells. Using recombinant proteins, T148I by itself was shown to cause only a 6-fold increase in the zanamivir 50% inhibitory concentration (IC50) and had no effect on inhibition by other drugs. The T148I substitution reduced NA activity by 50%, most likely by affecting the positioning of the 150 loop at the NA catalytic site. Using pyrosequencing, changes at T148 were detected in 35 (23%) of 150 MDCK cell-grown A(H3N2) viruses tested, which was lower than the frequency of changes at D151 (85%), an NA residue previously implicated in cell selection. We demonstrate that culturing of the A(H3N2) viruses (n = 11) at a low multiplicity of infection delayed the emergence of the NA variants with changes at position 148 and/or 151, especially when conducted in MDCK-SIAT1 cells. Our findings highlight the current challenges in monitoring susceptibility of influenza A(H3N2) viruses to the NAI class of antiviral drugs. JF - Antimicrobial Agents & Chemotherapy AU - Tamura, Daisuke AU - Nguyen, Ha T AU - Sleeman, Katrina AU - Levine, Marnie AU - Mishin, Vasiliy P AU - Yang, Hua AU - Guo, Zhu AU - Okomo-Adhiambo, Margaret AU - Xu, Xiyan AU - Stevens, James Y1 - 2013/12// PY - 2013 DA - Dec 2013 SP - 6141 EP - 6146 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 57 IS - 12 SN - 0066-4804, 0066-4804 KW - Virology & AIDS Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Drug resistance KW - Drug screening KW - Zanamivir KW - Oseltamivir KW - Influenza KW - Isoleucine KW - Influenza virus KW - Antiviral agents KW - Exo- alpha -sialidase KW - Multiplicity of infection KW - Active sites KW - Threonine KW - A 01340:Antibiotics & Antimicrobials KW - V 22340:Antiviral Agents UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1464504642?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Cell+Culture-Selected+Substitutions+in+Influenza+A%28H3N2%29+Neuraminidase+Affect+Drug+Susceptibility+Assessment&rft.au=Tamura%2C+Daisuke%3BNguyen%2C+Ha+T%3BSleeman%2C+Katrina%3BLevine%2C+Marnie%3BMishin%2C+Vasiliy+P%3BYang%2C+Hua%3BGuo%2C+Zhu%3BOkomo-Adhiambo%2C+Margaret%3BXu%2C+Xiyan%3BStevens%2C+James&rft.aulast=Tamura&rft.aufirst=Daisuke&rft.date=2013-12-01&rft.volume=57&rft.issue=12&rft.spage=6141&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.01364-13 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-11-01 N1 - Number of references - 35 N1 - Last updated - 2015-09-30 N1 - SubjectsTermNotLitGenreText - Isoleucine; Influenza; Antiviral agents; Drug resistance; Exo- alpha -sialidase; Active sites; Multiplicity of infection; Drug screening; Threonine; Zanamivir; Oseltamivir; Influenza virus DO - http://dx.doi.org/10.1128/AAC.01364-13 ER - TY - JOUR T1 - Ciguatera and scombroid fish poisoning in the United States. AN - 1461339077; 24093307 AB - Ciguatera and scombroid fish poisonings are common causes of fish-related foodborne illness in the United States; however, existing surveillance systems underestimate the overall human health impact. This study aimed to describe existing data on ciguatera and scombroid fish poisonings from outbreak and poison control center reports and to estimate the overall number of ciguatera and scombroid fish-poisoning illnesses, hospitalizations, and deaths in the United States. We analyzed outbreak data from the Foodborne Disease Outbreak Surveillance Systems (FDOSS) from 2000 to 2007 and poison control center call data from the National Poison Data System (NPDS) from 2005 to 2009 for reports of ciguatera and scombroid fish poisonings. Using a statistical model with many inputs, we adjusted the outbreak data for undercounting due to underreporting and underdiagnosis to generate estimates. Underreporting and underdiagnosis multipliers were derived from the poison control call data and the published literature. Annually, an average of 15 ciguatera and 28 scombroid fish-poisoning outbreaks, involving a total of 60 and 108 ill persons, respectively, were reported to FDOSS (2000-2007). NPDS reported an average of 173 exposure calls for ciguatoxin and 200 exposure calls for scombroid fish poisoning annually (2005-2009). After adjusting for undercounting, we estimated 15,910 (90% credible interval [CrI] 4140-37,408) ciguatera fish-poisoning illnesses annually, resulting in 343 (90% CrI 69-851) hospitalizations and three deaths (90% CrI 1-7). We estimated 35,142 (90% CrI: 10,496-78,128) scombroid fish-poisoning illnesses, resulting in 162 (90% CrI 0-558) hospitalizations and 0 deaths. Ciguatera and scombroid fish poisonings affect more Americans than reported in surveillance systems. Although additional data can improve these assessments, the estimated number of illnesses caused by seafood intoxication illuminates this public health problem. Efforts, including education, can reduce ciguatera and scombroid fish poisonings. JF - Foodborne pathogens and disease AU - Pennotti, Radha AU - Scallan, Elaine AU - Backer, Lorraine AU - Thomas, Jerry AU - Angulo, Frederick J AD - 1 National Center for Environmental Health/Agency for Toxic Substances and Disease Registry, Centers for Disease Control and Prevention , Atlanta, Georgia . Y1 - 2013/12// PY - 2013 DA - December 2013 SP - 1059 EP - 1066 VL - 10 IS - 12 KW - Marine Toxins KW - 0 KW - Ciguatoxins KW - 11050-21-8 KW - scombrotoxin KW - 82027-58-5 KW - Index Medicus KW - Animals KW - Public Health Surveillance KW - Hospitalization KW - Humans KW - Fishes KW - United States -- epidemiology KW - Seafood -- poisoning KW - Foodborne Diseases -- epidemiology KW - Ciguatera Poisoning -- epidemiology KW - Disease Outbreaks KW - Marine Toxins -- poisoning UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1461339077?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Foodborne+pathogens+and+disease&rft.atitle=Ciguatera+and+scombroid+fish+poisoning+in+the+United+States.&rft.au=Pennotti%2C+Radha%3BScallan%2C+Elaine%3BBacker%2C+Lorraine%3BThomas%2C+Jerry%3BAngulo%2C+Frederick+J&rft.aulast=Pennotti&rft.aufirst=Radha&rft.date=2013-12-01&rft.volume=10&rft.issue=12&rft.spage=1059&rft.isbn=&rft.btitle=&rft.title=Foodborne+pathogens+and+disease&rft.issn=1556-7125&rft_id=info:doi/10.1089%2Ffpd.2013.1514 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2015-04-16 N1 - Date created - 2013-11-22 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1089/fpd.2013.1514 ER - TY - JOUR T1 - Trends and geographic patterns in drug-poisoning death rates in the U.S., 1999-2009. AN - 1459561118; 24237925 AB - Drug poisoning mortality has increased substantially in the U.S. over the past 3 decades. Previous studies have described state-level variation and urban-rural differences in drug-poisoning deaths, but variation at the county level has largely not been explored in part because crude county-level death rates are often highly unstable. The goal of the study was to use small-area estimation techniques to produce stable county-level estimates of age-adjusted death rates (AADR) associated with drug poisoning for the U.S., 1999-2009, in order to examine geographic and temporal variation. Population-based observational study using data on 304,087 drug-poisoning deaths in the U.S. from the 1999-2009 National Vital Statistics Multiple Cause of Death Files (analyzed in 2012). Because of the zero-inflated and right-skewed distribution of drug-poisoning death rates, a two-stage modeling procedure was used in which the first stage modeled the probability of observing a death for a given county and year, and the second stage modeled the log-transformed drug-poisoning death rate given that a death occurred. Empirical Bayes estimates of county-level drug-poisoning death rates were mapped to explore temporal and geographic variation. Only 3% of counties had drug-poisoning AADRs greater than ten per 100,000 per year in 1999-2000, compared to 54% in 2008-2009. Drug-poisoning AADRs grew by 394% in rural areas compared to 279% for large central metropolitan counties, but the highest drug-poisoning AADRs were observed in central metropolitan areas from 1999 to 2009. There was substantial geographic variation in drug-poisoning mortality across the U.S. Published by American Journal of Preventive Medicine on behalf of American Journal of Preventive Medicine. JF - American journal of preventive medicine AU - Rossen, Lauren M AU - Khan, Diba AU - Warner, Margaret AD - Office of Analysis and Epidemiology, National Center for Health Statistics, CDC, Hyattsville, Maryland. Electronic address: lrossen@cdc.gov. Y1 - 2013/12// PY - 2013 DA - December 2013 SP - e19 EP - e25 VL - 45 IS - 6 KW - Index Medicus KW - Probability KW - Rural Population KW - Humans KW - Bayes Theorem KW - Urban Population KW - United States -- epidemiology KW - Time Factors KW - Cause of Death KW - Population Surveillance KW - Age Distribution KW - Drug Overdose -- mortality KW - Poisoning -- epidemiology KW - Models, Statistical KW - Drug Overdose -- epidemiology KW - Poisoning -- mortality UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1459561118?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+journal+of+preventive+medicine&rft.atitle=Trends+and+geographic+patterns+in+drug-poisoning+death+rates+in+the+U.S.%2C+1999-2009.&rft.au=Rossen%2C+Lauren+M%3BKhan%2C+Diba%3BWarner%2C+Margaret&rft.aulast=Rossen&rft.aufirst=Lauren&rft.date=2013-12-01&rft.volume=45&rft.issue=6&rft.spage=e19&rft.isbn=&rft.btitle=&rft.title=American+journal+of+preventive+medicine&rft.issn=1873-2607&rft_id=info:doi/10.1016%2Fj.amepre.2013.07.012 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2014-07-17 N1 - Date created - 2013-11-18 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Am J Prev Med. 2006 Dec;31(6):506-11 [17169712] Natl Vital Stat Rep. 2006 Jan 31;54(10):1-124 [16485447] J Pain. 2012 Oct;13(10):988-96 [23031398] J Environ Manage. 2007 Jun;83(4):478-90 [17166648] Annu Rev Public Health. 2007;28:95-111 [17112339] Natl Vital Stat Rep. 2007 Aug 21;55(19):1-119 [17867520] J Biopharm Stat. 2007;17(5):943-6 [17885875] Pharmacoepidemiol Drug Saf. 2008 Oct;17(10):997-1005 [18512264] JAMA. 2008 Dec 10;300(22):2613-20 [19066381] Am J Addict. 2009 Jan-Feb;18(1):5-14 [19219660] Natl Vital Stat Rep. 2009 Apr 17;57(14):1-134 [19788058] Stat Med. 2010 Aug 30;29(19):2012-27 [20683893] Am J Prev Med. 2010 Oct;39(4):357-63 [20837287] Stat Methods Med Res. 2011 Jun;20(3):175-89 [18815163] MMWR Morb Mortal Wkly Rep. 2011 Nov 4;60(43):1487-92 [22048730] MMWR Morb Mortal Wkly Rep. 2012 Jan 13;61(1):10-3 [22237030] MMWR Morb Mortal Wkly Rep. 2012 Feb 17;61(6):101-5 [22337174] NCHS Data Brief. 2011 Dec;(81):1-8 [22617462] MMWR Morb Mortal Wkly Rep. 2012 Jul 6;61(26):493-7 [22763888] Vital Health Stat 2. 2012 Jan;(154):1-65 [22783637] Natl Vital Stat Rep. 2011 Dec 7;59(10):1-126 [22808755] Ment Health Serv Res. 2004 Dec;6(4):239-46 [15588034] Natl Vital Stat Rep. 2004 Oct 12;53(5):1-115 [15587328] J Pharmacokinet Pharmacodyn. 2003 Oct;30(5):315-36 [14977163] Natl Vital Stat Rep. 2003 Sep 18;52(3):1-115 [14570230] Am J Epidemiol. 2003 Feb 1;157(3):273-8 [12543628] Natl Vital Stat Rep. 2002 Sep 16;50(15):1-119 [12382630] Natl Vital Stat Rep. 2001 Sep 21;49(8):1-113 [11591077] J Clin Epidemiol. 2001 Apr;54(4):343-9 [11297884] Stat Med. 1999 Dec 15;18(23):3189-200 [10602144] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1016/j.amepre.2013.07.012 ER - TY - CPAPER T1 - Overview of Mosquito Abatement Programs from a National Level T2 - 61st Annual Meeting of the Entomological Society of America (Entomology 2013) AN - 1490507469; 6254814 JF - 61st Annual Meeting of the Entomological Society of America (Entomology 2013) AU - McAllister, Janet Y1 - 2013/11/10/ PY - 2013 DA - 2013 Nov 10 KW - Aquatic insects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1490507469?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=61st+Annual+Meeting+of+the+Entomological+Society+of+America+%28Entomology+2013%29&rft.atitle=Overview+of+Mosquito+Abatement+Programs+from+a+National+Level&rft.au=McAllister%2C+Janet&rft.aulast=McAllister&rft.aufirst=Janet&rft.date=2013-11-10&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=61st+Annual+Meeting+of+the+Entomological+Society+of+America+%28Entomology+2013%29&rft.issn=&rft_id=info:doi/ L2 - http://esa.confex.com/esa/2013/webprogram/start.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-11-30 N1 - Last updated - 2014-02-10 ER - TY - JOUR T1 - Genetic variants within the MHC region are associated with immune responsiveness to childhood vaccinations. AN - 1446872664; 24075919 AB - The influence of genetic variability within the major histocompatibility complex (MHC) region on variations in immune responses to childhood vaccination was investigated. The study group consisted of 135 healthy infants who had been immunized with hepatitis B (HBV), 7-valent pneumococcal conjugate (PCV7), and diphtheria, tetanus, acellular pertussis (DTaP) vaccines according to standard childhood immunization schedules. Genotype analysis was performed on genomic DNA using Illumina Goldengate MHC panels (Mapping and Exon Centric). At the 1 year post vaccination check-up total, isotypic, and antigen-specific serum antibody levels were measured using multiplex immunoassays. A number of single nucleotide polymorphisms (SNPs) within MHC Class I and II genes were found to be associated with variations in the vaccine specific antibody responses and serum levels of immunoglobulins (IgG, IgM) and IgG isotypes (IgG1, IgG4) (all at p<0.001). Linkage disequilibrium patterns and functional annotations showed that significant SNPs were strongly correlated with other functional regulatory SNPs. These SNPs were found to regulate the expression of a group of genes involved in antigen processing and presentation including HLA-A, HLA-C, HLA-G, HLA-H, HLA-DRA, HLA-DRB1, HLA-DRB5, HLA-DQA1, HLA-DQB1, HLA-DOB, and TAP-2. The results suggest that genetic variations within particular MHC genes can influence immune response to common childhood vaccinations, which in turn may influence vaccine efficacy. Published by Elsevier Ltd. JF - Vaccine AU - Yucesoy, Berran AU - Talzhanov, Yerkebulan AU - Johnson, Victor J AU - Wilson, Nevin W AU - Biagini, Raymond E AU - Wang, Wei AU - Frye, Bonnie AU - Weissman, David N AU - Germolec, Dori R AU - Luster, Michael I AU - Barmada, Michael M AD - Toxicology and Molecular Biology Branch, CDC/NIOSH, Morgantown, WV, USA. Electronic address: byucesoy@cdc.gov. Y1 - 2013/11/04/ PY - 2013 DA - 2013 Nov 04 SP - 5381 EP - 5391 VL - 31 IS - 46 KW - Antibodies, Bacterial KW - 0 KW - Diphtheria-Tetanus-acellular Pertussis Vaccines KW - Hepatitis B Antibodies KW - Hepatitis B Vaccines KW - Heptavalent Pneumococcal Conjugate Vaccine KW - Pneumococcal Vaccines KW - Index Medicus KW - CPS KW - single nucleotide polymorphism KW - HBV KW - Genetic polymorphism KW - Major histocompatibility complex KW - surface antigen of hepatitis B virus KW - DTaP KW - SNP KW - PCV7 KW - major histocompatibility complex KW - haemophilus influenza type b KW - immunoglobulin KW - human leukocyte antigen KW - Childhood vaccine KW - PnPS KW - linkage disequilibrium KW - pneumococcal cell wall polysaccharide KW - IPV KW - heptavalent pneumococcal conjugate KW - HBsAg KW - pneumococcal polysaccharides KW - hepatitis B virus KW - OR KW - diphtheria, tetanus, and pertussis KW - MHC KW - Hib KW - odds ratio KW - HLA KW - inactivated polio vaccine KW - Immune response KW - LD KW - Ig KW - Infant KW - Humans KW - Antibodies, Bacterial -- blood KW - Male KW - Female KW - Hepatitis B Antibodies -- blood KW - Hepatitis B Vaccines -- immunology KW - Diphtheria-Tetanus-acellular Pertussis Vaccines -- administration & dosage KW - Polymorphism, Single Nucleotide KW - Pneumococcal Vaccines -- administration & dosage KW - Hepatitis B Vaccines -- administration & dosage KW - Major Histocompatibility Complex KW - Diphtheria-Tetanus-acellular Pertussis Vaccines -- immunology KW - Pneumococcal Vaccines -- immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1446872664?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Genetic+variants+within+the+MHC+region+are+associated+with+immune+responsiveness+to+childhood+vaccinations.&rft.au=Yucesoy%2C+Berran%3BTalzhanov%2C+Yerkebulan%3BJohnson%2C+Victor+J%3BWilson%2C+Nevin+W%3BBiagini%2C+Raymond+E%3BWang%2C+Wei%3BFrye%2C+Bonnie%3BWeissman%2C+David+N%3BGermolec%2C+Dori+R%3BLuster%2C+Michael+I%3BBarmada%2C+Michael+M&rft.aulast=Yucesoy&rft.aufirst=Berran&rft.date=2013-11-04&rft.volume=31&rft.issue=46&rft.spage=5381&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=1873-2518&rft_id=info:doi/10.1016%2Fj.vaccine.2013.09.026 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2014-06-02 N1 - Date created - 2013-10-28 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Genes Immun. 2001 Nov;2(7):367-72 [11704802] Nat Rev Immunol. 2011 Dec;11(12):823-36 [22076556] Physiol Rev. 2002 Jan;82(1):187-204 [11773612] MMWR Morb Mortal Wkly Rep. 2002 Jan 18;51(2):31-3 [11820528] Vaccine. 2002 Aug 19;20(25-26):3193-6 [12163271] Hum Immunol. 2003 Jan;64(1):103-9 [12507820] Autoimmun Rev. 2003 Sep;2(5):248-57 [12965175] Clin Diagn Lab Immunol. 2003 Sep;10(5):744-50 [12965898] Hepatology. 2003 Nov;38(5):1075-86 [14578844] Clin Diagn Lab Immunol. 2004 Jan;11(1):50-5 [14715544] Hepatology. 2004 Apr;39(4):978-88 [15057902] Trans Am Clin Climatol Assoc. 1981;92:142-51 [7025423] Ann Intern Med. 1986 Sep;105(3):356-60 [2943202] Hum Immunol. 1988 May;22(1):9-17 [2968966] J Med Virol. 1996 Dec;50(4):283-8 [8950683] Vaccine. 1997 Jan;15(1):3-6 [9041658] Tissue Antigens. 1997 Jul;50(1):8-14 [9243749] Am J Hum Genet. 1998 Feb;62(2):215-20 [9463343] Curr Opin Pediatr. 1998 Apr;10(2):208-15 [9608902] Tissue Antigens. 1998 Jun;51(6):593-604 [9694351] Tissue Antigens. 1998 Oct;52(4):374-80 [9820601] Vaccine. 1999 Mar 17;17(11-12):1525-31 [10195789] Bioinformatics. 2005 Jan 15;21(2):263-5 [15297300] Vaccine. 2012 Mar 9;30(12):2146-52 [22285888] Genome Res. 2012 Sep;22(9):1790-7 [22955989] J Immunol Methods. 2006 Feb 20;309(1-2):75-85 [16448665] Am J Hum Genet. 2007 Sep;81(3):559-75 [17701901] Trends Immunol. 2008 Mar;29(3):125-32 [18249584] Pediatrics. 2008 May;121(5):e1091-9 [18450852] Blood. 2008 May 15;111(10):4862-70 [18334671] Int J Immunogenet. 2008 Jun;35(3):179-92 [18397301] J Infect Dis. 2005 Feb 15;191(4):515-9 [15655774] Hepatology. 2005 Jun;41(6):1383-90 [15915462] J Infect Dis. 2006 Mar 1;193(5):655-63 [16453260] Bioinformatics. 2008 Dec 15;24(24):2938-9 [18974171] Genes Immun. 2009 Jan;10(1):56-67 [18830248] J Infect Dis. 2009 Sep 1;200(5):820-6 [19619059] Hum Genet. 2009 Nov;126(5):685-96 [19597844] Vaccine. 2009 Nov 16;27(49):6926-31 [19761839] Vaccine. 2009 Nov 23;27(50):6991-7 [19819209] Nature. 2010 Sep 2;467(7311):52-8 [20811451] Vaccine. 2011 Jan 17;29(4):706-11 [21111021] J Infect Dis. 2011 Jun 1;203(11):1546-55 [21592983] Genes Immun. 2011 Sep;12(6):457-65 [21368772] Hum Mol Genet. 2011 Oct 1;20(19):3893-8 [21764829] J Infect Dis. 2002 Jan 1;185(1):114-7 [11756990] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1016/j.vaccine.2013.09.026 ER - TY - CPAPER T1 - Racial disparities in chronic obstructive pulmonary disease (COPD) T2 - 141st American Public Health Association Annual Meeting and Exposition AN - 1433512811; 6234014 JF - 141st American Public Health Association Annual Meeting and Exposition AU - Croft, Janet AU - Zhang, Xingyou AU - Wheaton, Anne AU - Liu, Yong AU - Ford, Earl Y1 - 2013/11/02/ PY - 2013 DA - 2013 Nov 02 KW - Chronic obstructive pulmonary disease UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1433512811?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.atitle=Racial+disparities+in+chronic+obstructive+pulmonary+disease+%28COPD%29&rft.au=Croft%2C+Janet%3BZhang%2C+Xingyou%3BWheaton%2C+Anne%3BLiu%2C+Yong%3BFord%2C+Earl&rft.aulast=Croft&rft.aufirst=Janet&rft.date=2013-11-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/141am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-31 N1 - Last updated - 2013-09-19 ER - TY - CPAPER T1 - Non-sexual violence and connectedness in adolescence: What are the implications for STD/HIV infection in young adulthood? T2 - 141st American Public Health Association Annual Meeting and Exposition AN - 1433511621; 6233455 JF - 141st American Public Health Association Annual Meeting and Exposition AU - Steiner, Riley AU - Michael, Shannon AU - Hall, Jeffrey AU - Barrios, Lisa AU - Robin, Leah Y1 - 2013/11/02/ PY - 2013 DA - 2013 Nov 02 KW - Sexually-transmitted diseases KW - Human immunodeficiency virus KW - Aggression KW - Infection KW - Violence KW - Adolescents UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1433511621?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.atitle=Non-sexual+violence+and+connectedness+in+adolescence%3A+What+are+the+implications+for+STD%2FHIV+infection+in+young+adulthood%3F&rft.au=Steiner%2C+Riley%3BMichael%2C+Shannon%3BHall%2C+Jeffrey%3BBarrios%2C+Lisa%3BRobin%2C+Leah&rft.aulast=Steiner&rft.aufirst=Riley&rft.date=2013-11-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/141am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-31 N1 - Last updated - 2013-09-19 ER - TY - CPAPER T1 - Prevention Works: A public health approach to preventing violence that affects youth T2 - 141st American Public Health Association Annual Meeting and Exposition AN - 1433511267; 6233211 JF - 141st American Public Health Association Annual Meeting and Exposition AU - Spivak, Howard Y1 - 2013/11/02/ PY - 2013 DA - 2013 Nov 02 KW - Prevention KW - Aggression KW - Violence KW - Public health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1433511267?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.atitle=Prevention+Works%3A+A+public+health+approach+to+preventing+violence+that+affects+youth&rft.au=Spivak%2C+Howard&rft.aulast=Spivak&rft.aufirst=Howard&rft.date=2013-11-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/141am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-31 N1 - Last updated - 2013-09-19 ER - TY - CPAPER T1 - Providing credible health information for young women and bleeding disorders T2 - 141st American Public Health Association Annual Meeting and Exposition AN - 1433511113; 6233398 JF - 141st American Public Health Association Annual Meeting and Exposition AU - Sayers, Cynthia AU - Rhynders, Patricia AU - Thierry, JoAnn Y1 - 2013/11/02/ PY - 2013 DA - 2013 Nov 02 KW - Bleeding UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1433511113?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.atitle=Providing+credible+health+information+for+young+women+and+bleeding+disorders&rft.au=Sayers%2C+Cynthia%3BRhynders%2C+Patricia%3BThierry%2C+JoAnn&rft.aulast=Sayers&rft.aufirst=Cynthia&rft.date=2013-11-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/141am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-31 N1 - Last updated - 2013-09-19 ER - TY - CPAPER T1 - Prescription Drug Overdose - CDC's Public Health Approach T2 - 141st American Public Health Association Annual Meeting and Exposition AN - 1433511031; 6231566 JF - 141st American Public Health Association Annual Meeting and Exposition AU - Jones, Christopher Y1 - 2013/11/02/ PY - 2013 DA - 2013 Nov 02 KW - Overdose KW - Drugs KW - Public health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1433511031?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.atitle=Prescription+Drug+Overdose+-+CDC%27s+Public+Health+Approach&rft.au=Jones%2C+Christopher&rft.aulast=Jones&rft.aufirst=Christopher&rft.date=2013-11-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/141am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-31 N1 - Last updated - 2013-09-19 ER - TY - CPAPER T1 - Infectious disease surveillance and outbreak detection: Bioinformatic challenges T2 - 141st American Public Health Association Annual Meeting and Exposition AN - 1433510928; 6232559 JF - 141st American Public Health Association Annual Meeting and Exposition AU - MacCannell, Duncan Y1 - 2013/11/02/ PY - 2013 DA - 2013 Nov 02 KW - Infectious diseases KW - Disease detection KW - Bioinformatics KW - Outbreaks UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1433510928?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.atitle=Infectious+disease+surveillance+and+outbreak+detection%3A+Bioinformatic+challenges&rft.au=MacCannell%2C+Duncan&rft.aulast=MacCannell&rft.aufirst=Duncan&rft.date=2013-11-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/141am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-31 N1 - Last updated - 2013-09-19 ER - TY - CPAPER T1 - Playing it safe with hemophilia T2 - 141st American Public Health Association Annual Meeting and Exposition AN - 1433510890; 6232243 JF - 141st American Public Health Association Annual Meeting and Exposition AU - Simmons, Gretchen Y1 - 2013/11/02/ PY - 2013 DA - 2013 Nov 02 KW - Hemophilia UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1433510890?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.atitle=Playing+it+safe+with+hemophilia&rft.au=Simmons%2C+Gretchen&rft.aulast=Simmons&rft.aufirst=Gretchen&rft.date=2013-11-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/141am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-31 N1 - Last updated - 2013-09-19 ER - TY - CPAPER T1 - Preparing for extreme heat events in Maine (You've Got to be Kidding!) T2 - 141st American Public Health Association Annual Meeting and Exposition AN - 1433510889; 6233281 JF - 141st American Public Health Association Annual Meeting and Exposition AU - Smith, Andrew Y1 - 2013/11/02/ PY - 2013 DA - 2013 Nov 02 KW - Heat KW - USA, Maine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1433510889?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.atitle=Preparing+for+extreme+heat+events+in+Maine+%28You%27ve+Got+to+be+Kidding%21%29&rft.au=Smith%2C+Andrew&rft.aulast=Smith&rft.aufirst=Andrew&rft.date=2013-11-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/141am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-31 N1 - Last updated - 2013-09-19 ER - TY - CPAPER T1 - Association between disability, sleep and chronic conditions T2 - 141st American Public Health Association Annual Meeting and Exposition AN - 1433510877; 6232989 JF - 141st American Public Health Association Annual Meeting and Exposition AU - Courtney-Long, Elizabeth AU - Stevens, Alissa Y1 - 2013/11/02/ PY - 2013 DA - 2013 Nov 02 KW - Sleep KW - Disabilities UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1433510877?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.atitle=Association+between+disability%2C+sleep+and+chronic+conditions&rft.au=Courtney-Long%2C+Elizabeth%3BStevens%2C+Alissa&rft.aulast=Courtney-Long&rft.aufirst=Elizabeth&rft.date=2013-11-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/141am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-31 N1 - Last updated - 2013-09-19 ER - TY - CPAPER T1 - Addressing cognitive impairment and promoting functioning: State and local public health initiatives T2 - 141st American Public Health Association Annual Meeting and Exposition AN - 1433510865; 6231850 JF - 141st American Public Health Association Annual Meeting and Exposition AU - Anderson, Lynda AU - Egge, Robert AU - Baumgart, Matthew AU - Deokar, Angela AU - Morrison, Catherine Y1 - 2013/11/02/ PY - 2013 DA - 2013 Nov 02 KW - Cognitive ability KW - Public health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1433510865?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.atitle=Addressing+cognitive+impairment+and+promoting+functioning%3A+State+and+local+public+health+initiatives&rft.au=Anderson%2C+Lynda%3BEgge%2C+Robert%3BBaumgart%2C+Matthew%3BDeokar%2C+Angela%3BMorrison%2C+Catherine&rft.aulast=Anderson&rft.aufirst=Lynda&rft.date=2013-11-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/141am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-31 N1 - Last updated - 2013-09-19 ER - TY - CPAPER T1 - Assessing interventions to increase use of reproductive health (RH) and sexually transmitted infection (STI) services by male clients at family planning (FP) clinics T2 - 141st American Public Health Association Annual Meeting and Exposition AN - 1433510418; 6231840 JF - 141st American Public Health Association Annual Meeting and Exposition AU - Warner, Lee AU - Johnson, David AU - Salomon, Sarah AU - Fine, David Y1 - 2013/11/02/ PY - 2013 DA - 2013 Nov 02 KW - Family planning KW - Infectious diseases KW - Sexually-transmitted diseases KW - Intervention KW - Reproduction UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1433510418?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.atitle=Assessing+interventions+to+increase+use+of+reproductive+health+%28RH%29+and+sexually+transmitted+infection+%28STI%29+services+by+male+clients+at+family+planning+%28FP%29+clinics&rft.au=Warner%2C+Lee%3BJohnson%2C+David%3BSalomon%2C+Sarah%3BFine%2C+David&rft.aulast=Warner&rft.aufirst=Lee&rft.date=2013-11-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/141am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-31 N1 - Last updated - 2013-09-19 ER - TY - CPAPER T1 - School health professional's attitudes about school-located vaccination for influenza T2 - 141st American Public Health Association Annual Meeting and Exposition AN - 1433510097; 6234546 JF - 141st American Public Health Association Annual Meeting and Exposition AU - Kang, Yoonjae AU - Zhang, Fan AU - Guled, Hodan AU - Pagadala, Nina AU - Honeycutt, Amanda AU - Vogt, Tara Y1 - 2013/11/02/ PY - 2013 DA - 2013 Nov 02 KW - Influenza KW - Attitudes KW - Schools KW - Vaccination UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1433510097?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.atitle=School+health+professional%27s+attitudes+about+school-located+vaccination+for+influenza&rft.au=Kang%2C+Yoonjae%3BZhang%2C+Fan%3BGuled%2C+Hodan%3BPagadala%2C+Nina%3BHoneycutt%2C+Amanda%3BVogt%2C+Tara&rft.aulast=Kang&rft.aufirst=Yoonjae&rft.date=2013-11-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/141am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-31 N1 - Last updated - 2013-09-19 ER - TY - CPAPER T1 - Sickle cell disease education and awareness in your community T2 - 141st American Public Health Association Annual Meeting and Exposition AN - 1433510001; 6232241 JF - 141st American Public Health Association Annual Meeting and Exposition AU - Simmons, Gretchen Y1 - 2013/11/02/ PY - 2013 DA - 2013 Nov 02 KW - Education KW - Sickle cell disease UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1433510001?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.atitle=Sickle+cell+disease+education+and+awareness+in+your+community&rft.au=Simmons%2C+Gretchen&rft.aulast=Simmons&rft.aufirst=Gretchen&rft.date=2013-11-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/141am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-31 N1 - Last updated - 2013-09-19 ER - TY - CPAPER T1 - Tweeting up a storm: The centers for disease control and prevention's (CDC) social media messaging and Hurricane Sandy T2 - 141st American Public Health Association Annual Meeting and Exposition AN - 1433508913; 6232284 JF - 141st American Public Health Association Annual Meeting and Exposition AU - Dempsey, Jay AU - Briseno, Lisa AU - Hawk, Nicole Y1 - 2013/11/02/ PY - 2013 DA - 2013 Nov 02 KW - Hurricanes KW - Prevention KW - Disease control KW - Storms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1433508913?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.atitle=Tweeting+up+a+storm%3A+The+centers+for+disease+control+and+prevention%27s+%28CDC%29+social+media+messaging+and+Hurricane+Sandy&rft.au=Dempsey%2C+Jay%3BBriseno%2C+Lisa%3BHawk%2C+Nicole&rft.aulast=Dempsey&rft.aufirst=Jay&rft.date=2013-11-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/141am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-31 N1 - Last updated - 2013-09-19 ER - TY - CPAPER T1 - Disability inclusion at CDC - a progress report T2 - 141st American Public Health Association Annual Meeting and Exposition AN - 1433508644; 6232512 JF - 141st American Public Health Association Annual Meeting and Exposition AU - Campbell, Vincent Y1 - 2013/11/02/ PY - 2013 DA - 2013 Nov 02 KW - Disabilities KW - Progress reports UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1433508644?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.atitle=Disability+inclusion+at+CDC+-+a+progress+report&rft.au=Campbell%2C+Vincent&rft.aulast=Campbell&rft.aufirst=Vincent&rft.date=2013-11-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/141am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-31 N1 - Last updated - 2013-09-19 ER - TY - CPAPER T1 - Annual exploration of injury and emergency health data issues T2 - 141st American Public Health Association Annual Meeting and Exposition AN - 1433508537; 6232580 JF - 141st American Public Health Association Annual Meeting and Exposition AU - Annest, Joseph AU - Cook, Larry AU - Hedegaard, Holly AU - Warner, Margaret Y1 - 2013/11/02/ PY - 2013 DA - 2013 Nov 02 KW - Data processing KW - Injuries KW - Emergencies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1433508537?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.atitle=Annual+exploration+of+injury+and+emergency+health+data+issues&rft.au=Annest%2C+Joseph%3BCook%2C+Larry%3BHedegaard%2C+Holly%3BWarner%2C+Margaret&rft.aulast=Annest&rft.aufirst=Joseph&rft.date=2013-11-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/141am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-31 N1 - Last updated - 2013-09-19 ER - TY - CPAPER T1 - Starting the conversation: How to tell your friends about hemophilia T2 - 141st American Public Health Association Annual Meeting and Exposition AN - 1433508529; 6232242 JF - 141st American Public Health Association Annual Meeting and Exposition AU - Simmons, Gretchen Y1 - 2013/11/02/ PY - 2013 DA - 2013 Nov 02 KW - Hemophilia UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1433508529?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.atitle=Starting+the+conversation%3A+How+to+tell+your+friends+about+hemophilia&rft.au=Simmons%2C+Gretchen&rft.aulast=Simmons&rft.aufirst=Gretchen&rft.date=2013-11-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/141am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-31 N1 - Last updated - 2013-09-19 ER - TY - CPAPER T1 - Gender difference in prevalence of vision impairment among those aged >=65 years reporting chronic conditions: Findings from the 2007-2011 national health interview survey T2 - 141st American Public Health Association Annual Meeting and Exposition AN - 1433508301; 6232430 JF - 141st American Public Health Association Annual Meeting and Exposition AU - Crews, John AU - Chou, Chiu-Fang AU - Zhang, Xinzhi AU - Saaddine, Jinan Y1 - 2013/11/02/ PY - 2013 DA - 2013 Nov 02 KW - Vision KW - Sex differences KW - Sex UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1433508301?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.atitle=Gender+difference+in+prevalence+of+vision+impairment+among+those+aged+%26gt%3B%3D65+years+reporting+chronic+conditions%3A+Findings+from+the+2007-2011+national+health+interview+survey&rft.au=Crews%2C+John%3BChou%2C+Chiu-Fang%3BZhang%2C+Xinzhi%3BSaaddine%2C+Jinan&rft.aulast=Crews&rft.aufirst=John&rft.date=2013-11-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/141am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-31 N1 - Last updated - 2013-09-19 ER - TY - CPAPER T1 - Global to local initiatives to address alzheimer's disease and dementia: Plans and priorities T2 - 141st American Public Health Association Annual Meeting and Exposition AN - 1433508259; 6232728 JF - 141st American Public Health Association Annual Meeting and Exposition AU - Anderson, Lynda AU - Splaine, Michael AU - Hoffman, David AU - Levy-Storms, Lene AU - Baumgart, Matthew Y1 - 2013/11/02/ PY - 2013 DA - 2013 Nov 02 KW - Neurodegenerative diseases KW - Alzheimer's disease KW - Dementia disorders KW - Priorities UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1433508259?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.atitle=Global+to+local+initiatives+to+address+alzheimer%27s+disease+and+dementia%3A+Plans+and+priorities&rft.au=Anderson%2C+Lynda%3BSplaine%2C+Michael%3BHoffman%2C+David%3BLevy-Storms%2C+Lene%3BBaumgart%2C+Matthew&rft.aulast=Anderson&rft.aufirst=Lynda&rft.date=2013-11-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=141st+American+Public+Health+Association+Annual+Meeting+and+Exposition&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/141am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-31 N1 - Last updated - 2013-09-19 ER - TY - JOUR T1 - Programme and policy options for preventing obesity in China AN - 1837344861; 18739783 AB - By 2002, China's prevalence of overweight and obesity among adults was 18.9 and 2.9%, respectively. The replacement of traditional Chinese diet with 'Western diet', major declines in all phases of activity and increased sedentary activity are cited as the main reasons explaining the rapid increase in overweight and obesity, which bring major economic and health costs. The Nutrition Improvement Work Management Approach was released in 2010. Overweight and obesity prevention-related policies were added to national planning for disease prevention and control. The Guidelines for Prevention and Control of Overweight and Obesity of Chinese Adults and the School-age Children and Teenagers Overweight and Obesity Prevention and Control Guidelines in China were promulgated in 2003 and 2007, respectively. Few education programmes have been implemented. Selected academic intervention research projects dominate with a focus on reducing child obesity and promoting healthier diets; increasing physical activity and reducing sedentary time; and facilitating changes in family, school, social and cultural environments. Intervention samples are small and have not addressed the increasing rates of obesity throughout the entire population. Government provision of effective policy measures, multisectoral cooperation and increasing corporate social responsibility are keys to curbing the trend towards overweight and obesity in China. JF - Obesity Reviews AU - Wang, H AU - Zhai, F AD - National Institute for Nutrition and Food Safety. Chinese Center for Disease Control and Prevention Y1 - 2013/11// PY - 2013 DA - November 2013 SP - 134 EP - 140 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 14 SN - 1467-7881, 1467-7881 KW - Physical Education Index KW - Obesity KW - Programs KW - Schools KW - Preventive health KW - Policy KW - Economics KW - Diet KW - Adults KW - Nutrition KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1837344861?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Obesity+Reviews&rft.atitle=Programme+and+policy+options+for+preventing+obesity+in+China&rft.au=Wang%2C+H%3BZhai%2C+F&rft.aulast=Wang&rft.aufirst=H&rft.date=2013-11-01&rft.volume=14&rft.issue=&rft.spage=134&rft.isbn=&rft.btitle=&rft.title=Obesity+Reviews&rft.issn=14677881&rft_id=info:doi/10.1111%2Fobr.12106 LA - English DB - Physical Education Index N1 - Date revised - 2016-11-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Obesity; Programs; Schools; Preventive health; Policy; Economics; Adults; Diet; Nutrition DO - http://dx.doi.org/10.1111/obr.12106 ER - TY - JOUR T1 - Neurologic Melioidosis in an Imported Pigtail Macaque (Macaca nemestrina) AN - 1551625898; 20380441 AB - Burkholderia pseudomallei is the cause of melioidosis in humans and other animals. Disease occurs predominately in Asia and Australia. It is rare in North America, and affected people and animals typically have a history of travel to (in human cases) or importation from (in animal cases) endemic areas. We describe the gross and histopathologic features and the microbiologic, molecular, and immunohistochemical diagnoses of a case of acute meningoencephalomyelitis and focal pneumonia caused by B. pseudomallei infection in a pigtail macaque that was imported from Indonesia to the United States for research purposes. This bacterium has been classified as a Tier 1 overlap select agent and toxin; therefore, recognition of pathologic features, along with accurate and timely confirmatory diagnostic testing, in naturally infected research animals is imperative to protect animals and personnel in the laboratory animal setting. JF - Veterinary Pathology AU - Ritter, J M AU - Sanchez, S AU - Jones, T L AU - Zaki AU - Drew, C P AD - Infectious Diseases Pathology Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA, jritter@cdc.gov Y1 - 2013/11// PY - 2013 DA - Nov 2013 SP - 1139 EP - 1144 PB - Allen Press, Inc., 810 East Tenth St. Lawrence KS 66044 United States VL - 50 IS - 6 SN - 0300-9858, 0300-9858 KW - Microbiology Abstracts B: Bacteriology KW - Burkholderia pseudomallei KW - immunohistochemistry KW - macaque KW - melioidosis KW - meningoencephalomyelitis KW - neurologic KW - PCR KW - Travel KW - Personnel KW - Macaca nemestrina KW - Melioidosis KW - Laboratory animals KW - Infection KW - Importation KW - Pneumonia KW - Toxins KW - J 02410:Animal Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1551625898?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Veterinary+Pathology&rft.atitle=Neurologic+Melioidosis+in+an+Imported+Pigtail+Macaque+%28Macaca+nemestrina%29&rft.au=Ritter%2C+J+M%3BSanchez%2C+S%3BJones%2C+T+L%3BZaki%3BDrew%2C+C+P&rft.aulast=Ritter&rft.aufirst=J&rft.date=2013-11-01&rft.volume=50&rft.issue=6&rft.spage=1139&rft.isbn=&rft.btitle=&rft.title=Veterinary+Pathology&rft.issn=03009858&rft_id=info:doi/10.1177%2F0300985813485249 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-08-01 N1 - Last updated - 2014-10-02 N1 - SubjectsTermNotLitGenreText - Travel; Personnel; Laboratory animals; Melioidosis; Importation; Infection; Toxins; Pneumonia; Burkholderia pseudomallei; Macaca nemestrina DO - http://dx.doi.org/10.1177/0300985813485249 ER - TY - JOUR T1 - The Effects of Impact Vibration on Peripheral Blood Vessels and Nerves AN - 1512334488; 19443833 AB - Research regarding the risk of developing hand-arm vibration syndrome after exposure to impact vibration has produced conflicting results. This study used an established animal model of vibration-induced dysfunction to determine how exposure to impact vibration affects peripheral blood vessels and nerves. The tails of male rats were exposed to a single bout of impact vibration (15 min exposure, at a dominant frequency of 30 Hz and an unweighted acceleration of approxi-mately 345 m/s super(2)) generated by a riveting hammer. Responsiveness of the ventral tail artery to adrenoreceptor-mediated vasoconstriction and acetylcholine-mediated re-dilation was measured ex vivo. Ventral tail nerves and nerve endings in the skin were assessed using morphological and immunohistochemical techniques. Impact vibration did not alter vascular responsiveness to any factors or affect trunk nerves. However, 4 days following exposure there was an increase in protein-gene product (PGP) 9.5 staining around hair follicles. A single exposure to impact vibration, with the exposure characteristics described above, affects peripheral nerves but not blood vessels. JF - Industrial Health AU - KRAJNAK, Kristine M AU - WAUGH, Stacey AU - JOHNSON, Claud AU - MILLER, Roger AU - XU, Xueyan AU - WARREN, Christopher AU - DONG, Ren G AD - Engineering and Controls Technology Branch, National Institutes for Occupational Safety and Health, USA, kskl@cdc.gov Y1 - 2013/11// PY - 2013 DA - Nov 2013 SP - 572 EP - 580 PB - National Institute of Industrial Health. Japan., 21-1 Nagao 6-chome Kawasaki-shi 214-0023 Kanagawa-ken Japan VL - 51 IS - 6 SN - 0019-8366, 0019-8366 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Vibration KW - Cardiovascular disorders KW - Muscloskeletal disordrs KW - Sensorineural disorders KW - Animal model KW - Rats KW - Risk assessment KW - Skin KW - Hand-arm vibration syndrome KW - Risk factors KW - Animal models KW - Hair KW - Occupational exposure KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1512334488?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Industrial+Health&rft.atitle=The+Effects+of+Impact+Vibration+on+Peripheral+Blood+Vessels+and+Nerves&rft.au=KRAJNAK%2C+Kristine+M%3BWAUGH%2C+Stacey%3BJOHNSON%2C+Claud%3BMILLER%2C+Roger%3BXU%2C+Xueyan%3BWARREN%2C+Christopher%3BDONG%2C+Ren+G&rft.aulast=KRAJNAK&rft.aufirst=Kristine&rft.date=2013-11-01&rft.volume=51&rft.issue=6&rft.spage=572&rft.isbn=&rft.btitle=&rft.title=Industrial+Health&rft.issn=00198366&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-04-01 N1 - Last updated - 2015-04-16 N1 - SubjectsTermNotLitGenreText - Risk assessment; Rats; Hand-arm vibration syndrome; Skin; Risk factors; Vibration; Animal models; Hair; Occupational exposure ER - TY - JOUR T1 - Violent crime rates as a proxy for the social determinants of sexually transmissible infection rates: the consistent state-level correlation between violent crime and reported sexually transmissible infections in the United States, 1981-2010 AN - 1496663867; 201402058 AB - Background: Numerous social determinants of health are associated with violent crime rates and sexually transmissible infection (STI) rates. This report aims to illustrate the potential usefulness of violent crime rates as a proxy for the social determinants of STI rates. Methods: For each year from 1981 to 2010, we assessed the strength of the association between the violent crime rate and the gonorrhoea (Neisseria gonorrhoeae) rate (number of total reported cases per 100,000) at the state level. Specifically, for each year, we calculated Pearson correlation coefficients (and P-values) between two variables (the violent crime rate and the natural log of the gonorrhoea rate) for all 50 states and Washington, DC. For comparison, we also examined the correlation between gonorrhoea rates, and rates of poverty and unemployment. We repeated the analysis using overall syphilis rates instead of overall gonorrhoea rates. Results: The correlation between gonorrhoea and violent crime was significant at the P < 0.001 level for every year from 1981 to 2010. Syphilis rates were also consistently correlated with violent crime rates. In contrast, the P-value for the correlation coefficient exceeded 0.05 in 9 of the 30 years for the association between gonorrhoea and poverty, and in 17 of the 30 years for that between gonorrhoea and unemployment. Conclusions: Because violent crime is associated with many social determinants of STIs and because it is consistently associated with STI rates, violent crime rates can be a useful proxy for the social determinants of health in statistical analyses of STI rates. Adapted from the source document. JF - Sexual Health AU - Chesson, Harrell W AU - Owusu-Edusei, Kwame AU - Leichliter, Jami S AU - Aral, Sevgi O AD - Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention Y1 - 2013/11// PY - 2013 DA - November 2013 SP - 419 EP - 423 PB - CSIRO Publishing, Collingwood Australia VL - 10 IS - 5 SN - 1448-5028, 1448-5028 KW - epidemiology, gonorrhoa, poverty, syphilis. KW - Unemployment KW - Violent crime KW - Syphilis KW - Social factors KW - Sexually transmitted diseases KW - Gonorrhoea KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1496663867?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Sexual+Health&rft.atitle=Violent+crime+rates+as+a+proxy+for+the+social+determinants+of+sexually+transmissible+infection+rates%3A+the+consistent+state-level+correlation+between+violent+crime+and+reported+sexually+transmissible+infections+in+the+United+States%2C+1981-2010&rft.au=Chesson%2C+Harrell+W%3BOwusu-Edusei%2C+Kwame%3BLeichliter%2C+Jami+S%3BAral%2C+Sevgi+O&rft.aulast=Chesson&rft.aufirst=Harrell&rft.date=2013-11-01&rft.volume=10&rft.issue=5&rft.spage=419&rft.isbn=&rft.btitle=&rft.title=Sexual+Health&rft.issn=14485028&rft_id=info:doi/10.1071%2FSH13006 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2014-02-01 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Violent crime; Gonorrhoea; Sexually transmitted diseases; Social factors; Unemployment; Syphilis DO - http://dx.doi.org/10.1071/SH13006 ER - TY - JOUR T1 - Seasonal Influenza Vaccination Coverage Among Adult Populations in the United States, 2005-2011 AN - 1492617734; 18890622 AB - The most effective strategy for preventing influenza is annual vaccination. We analyzed 2005-2011 data from the National Health Interview Survey (NHIS), using Kaplan-Meier survival analysis to estimate cumulative proportions of persons reporting influenza vaccination in the 2004-2005 through 2010-2011 seasons for persons aged greater than or equal to 18, 18-49, 50-64, and greater than or equal to 65 years, persons with high-risk conditions, and health-care personnel. We compared vaccination coverage by race/ethnicity within each age and high-risk group. Vaccination coverage among adults aged greater than or equal to 18 years increased from 27.4% during the 2005-2006 influenza season to 38.1% during the 2010-2011 season, with an average increase of 2.2% annually. From the 2005-2006 season to the 2010-2011 season, coverage increased by 10-12 percentage points for all groups except adults aged greater than or equal to 65 years. Coverage for the 2010-2011 season was 70.2% for adults aged greater than or equal to 65 years, 43.7% for adults aged 50-64 years, 36.7% for persons aged 18-49 years with high-risk conditions, and 55.8% for health-care personnel. In most subgroups, coverage during the 2010-2011 season was significantly lower among non-Hispanic blacks and Hispanics than among non-Hispanic whites. Vaccination coverage among adults under age 65 years increased from 2005-2006 through 2010-2011, but substantial racial/ethnic disparities remained in most age groups. Targeted efforts are needed to improve influenza vaccination coverage and reduce disparities. JF - American Journal of Epidemiology AU - Lu, Peng-Jun AU - Singleton, James A AU - Euler, Gary L AU - Williams, Walter W AU - Bridges, Carolyn B AD - Correspondence to Dr. Peng-Jun Lu, Immunization Services Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Mail Stop A-19, Atlanta, GA 30333. Y1 - 2013/11/01/ PY - 2013 DA - 2013 Nov 01 SP - 1478 EP - 1487 PB - Oxford University Press, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 178 IS - 9 SN - 0002-9262, 0002-9262 KW - Virology & AIDS Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - Age KW - Data processing KW - Survival KW - Vaccination KW - Influenza KW - USA KW - Sulfur dioxide KW - Personnel KW - Risk groups KW - Age groups KW - Seasonal variations KW - Ethnic groups KW - Races KW - R2 23060:Medical and environmental health KW - H 12000:Epidemiology and Public Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1492617734?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Epidemiology&rft.atitle=Seasonal+Influenza+Vaccination+Coverage+Among+Adult+Populations+in+the+United+States%2C+2005-2011&rft.au=Lu%2C+Peng-Jun%3BSingleton%2C+James+A%3BEuler%2C+Gary+L%3BWilliams%2C+Walter+W%3BBridges%2C+Carolyn+B&rft.aulast=Lu&rft.aufirst=Peng-Jun&rft.date=2013-11-01&rft.volume=178&rft.issue=9&rft.spage=1478&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Epidemiology&rft.issn=00029262&rft_id=info:doi/10.1093%2Faje%2Fkwt158 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-12-01 N1 - Last updated - 2014-05-15 N1 - SubjectsTermNotLitGenreText - Influenza; Age; Data processing; Personnel; Survival; Risk groups; Vaccination; Races; Ethnic groups; Sulfur dioxide; Age groups; Seasonal variations; USA DO - http://dx.doi.org/10.1093/aje/kwt158 ER - TY - JOUR T1 - Molecular Resistance Mechanisms of Macrolide-Resistant Invasive Streptococcus pneumoniae Isolates from Alaska, 1986 to 2010 AN - 1458539091; 18745801 AB - The rapid emergence of antibiotic-resistant pneumococcal strains has reduced treatment options. The aim of this study was to determine antimicrobial susceptibilities, serotype distributions, and molecular resistance mechanisms among macrolide-resistant invasive pneumococcal isolates in Alaska from 1986 to 2010. We identified cases of invasive pneumococcal disease in Alaska from 1986 to 2010 through statewide population-based laboratory surveillance. All invasive pneumococcal isolates submitted to the Arctic Investigations Program laboratory were confirmed by standard microbiological methods and serotyped by slide agglutination and the Quellung reaction. MICs were determined by the broth microdilution method, and macrolide-resistant genotypes were determined by multiplex PCR. Among 2,923 invasive pneumococcal isolates recovered from 1986 to 2010, 270 (9.2%) were nonsusceptible to erythromycin; 177 (66%) erythromycin-nonsusceptible isolates demonstrated coresistance to penicillin, and 167 (62%) were multidrug resistant. The most frequent serotypes among the macrolide-resistant isolates were serotypes 6B (23.3%), 14 (20.7%), 19A (16.7%), 9V (8.9%), 19F (6.3%), 6A (5.6%), and 23F (4.8%). mef and erm(B) genes were detected in 207 (77%) and 32 (12%) of the isolates, respectively. Nineteen (7%) of the erythromycin-nonsusceptible isolates contained both mef and erm(B) genotypes; 15 were of serotype 19A. There was significant year-to-year variation in the proportion of isolates that were nonsusceptible to erythromycin (P < 0.001). Macrolide resistance among pneumococcal isolates from Alaska is mediated predominantly by mef genes, and this has not changed significantly over time. However, there was a statistically significant increase in the proportion of isolates that possess both erm(B) and mef, primarily due to serotype 19A isolates. JF - Antimicrobial Agents & Chemotherapy AU - Rudolph, Karen AU - Bulkow, Lisa AU - Bruce, Michael AU - Zulz, Tammy AU - Reasonover, Alisa AU - Harker-Jones, Marcella AU - Hurlburt, Debby AU - Hennessy, Thomas Y1 - 2013/11// PY - 2013 DA - Nov 2013 SP - 5415 EP - 5422 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 57 IS - 11 SN - 0066-4804, 0066-4804 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Streptococcus pneumoniae KW - Agglutination KW - Serotypes KW - Statistical analysis KW - Polymerase chain reaction KW - Multidrug resistance KW - Genotypes KW - Erythromycin KW - Minimum inhibitory concentration KW - Penicillin KW - Antimicrobial agents KW - A 01340:Antibiotics & Antimicrobials KW - J 02450:Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1458539091?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Molecular+Resistance+Mechanisms+of+Macrolide-Resistant+Invasive+Streptococcus+pneumoniae+Isolates+from+Alaska%2C+1986+to+2010&rft.au=Rudolph%2C+Karen%3BBulkow%2C+Lisa%3BBruce%2C+Michael%3BZulz%2C+Tammy%3BReasonover%2C+Alisa%3BHarker-Jones%2C+Marcella%3BHurlburt%2C+Debby%3BHennessy%2C+Thomas&rft.aulast=Rudolph&rft.aufirst=Karen&rft.date=2013-11-01&rft.volume=57&rft.issue=11&rft.spage=5415&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.00319-13 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-11-01 N1 - Number of references - 50 N1 - Last updated - 2013-12-16 N1 - SubjectsTermNotLitGenreText - Agglutination; Serotypes; Statistical analysis; Polymerase chain reaction; Multidrug resistance; Genotypes; Erythromycin; Minimum inhibitory concentration; Penicillin; Antimicrobial agents; Streptococcus pneumoniae DO - http://dx.doi.org/10.1128/AAC.00319-13 ER - TY - JOUR T1 - Bioluminescence-Based Neuraminidase Inhibition Assay for Monitoring Influenza Virus Drug Susceptibility in Clinical Specimens AN - 1458536394; 18745845 AB - The QFlu prototype bioluminescence-based neuraminidase (NA) inhibition (NI) assay kit was designed to detect NA inhibitor (NAI)-resistant influenza viruses at point of care. Here, we evaluated its suitability for drug susceptibility assessment at a surveillance laboratory. A comprehensive panel of reference viruses (n = 14) and a set of 90 seasonal influenza virus A and B isolates were included for testing with oseltamivir and/or zanamivir in the QFlu assay using the manufacturer-recommended protocol and a modified version attuned to surveillance requirements. The 50% inhibitory concentrations (IC50s) generated were compared with those of NI assays currently used for monitoring influenza drug susceptibility, the fluorescent (FL) and chemiluminescent (CL) assays. To provide proof of principle, clinical specimens (n = 235) confirmed by real-time reverse transcription (RT)-PCR to contain influenza virus A(H1N1)pdm09 and prescreened for the oseltamivir resistance marker H275Y using pyrosequencing were subsequently tested in the QFlu assay. All three NI assays were able to discriminate the reference NA variants and their matching wild-type viruses based on the difference in their IC50s. Unless the antigenic types were first identified, certain NA variants (e.g., H3N2 with E119V) could be detected among seasonal viruses using the FL assays only. Notably, the QFlu assay identified oseltamivir-resistant A(H1N1)pdm09 viruses carrying the H275Y marker directly in clinical specimens, which is not feasible with the other two phenotypic assays, which required prior virus culturing in cells. Furthermore, The QFlu assay allows detection of the influenza virus A and B isolates carrying established and potential NA inhibitor resistance markers and may become a useful tool for monitoring drug resistance in clinical specimens. JF - Antimicrobial Agents & Chemotherapy AU - Marjuki, Henju AU - Mishin, Vasiliy P AU - Sleeman, Katrina AU - Okomo-Adhiambo, Margaret AU - Sheu, Tiffany G AU - Guo, Lizheng AU - Xu, Xiyan AU - Gubareva, Larisa V Y1 - 2013/11// PY - 2013 DA - Nov 2013 SP - 5209 EP - 5215 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 57 IS - 11 SN - 0066-4804, 0066-4804 KW - Virology & AIDS Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Disease resistance KW - Influenza KW - Influenza A virus KW - V:22340 KW - A:01340 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1458536394?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Bioluminescence-Based+Neuraminidase+Inhibition+Assay+for+Monitoring+Influenza+Virus+Drug+Susceptibility+in+Clinical+Specimens&rft.au=Marjuki%2C+Henju%3BMishin%2C+Vasiliy+P%3BSleeman%2C+Katrina%3BOkomo-Adhiambo%2C+Margaret%3BSheu%2C+Tiffany+G%3BGuo%2C+Lizheng%3BXu%2C+Xiyan%3BGubareva%2C+Larisa+V&rft.aulast=Marjuki&rft.aufirst=Henju&rft.date=2013-11-01&rft.volume=57&rft.issue=11&rft.spage=5209&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.01086-13 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-11-01 N1 - Number of references - 1 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Influenza; Influenza A virus DO - http://dx.doi.org/10.1128/AAC.01086-13 ER - TY - JOUR T1 - Structural Analysis of the Hemagglutinin from the Recent 2013 H7N9 Influenza Virus AN - 1458532613; 18746051 AB - In March 2013, the Chinese Center for Disease Control and Prevention reported human infections with an H7N9 influenza virus, and by 20 July 2013, the numbers of laboratory-confirmed cases had climbed to 134, including 43 fatalities and 127 hospitalizations. The newly emerging H7N9 viruses constitute an obvious public health concern because of the apparent severity of this outbreak. Here we focus on the hemagglutinins (HAs) of these viruses and assess their receptor binding phenotype in relation to previous HAs studied. Glycan microarray and kinetic analyses of recombinant A(H7N9) HAs were performed to compare the receptor binding profile of wild-type receptor binding site variants at position 217, a residue analogous to one of two positions known to switch avian to human receptor preference in H2N2 and H3N2 viruses. Two recombinant A(H7N9) HAs were structurally characterized, and a mutational study of the receptor binding site was performed to analyze important residues that can affect receptor preference and affinity. Results highlight a weak human receptor preference of the H7N9 HAs, suggesting that these viruses require further adaptation in order to adapt fully to humans. JF - Journal of Virology AU - Yang, Hua AU - Carney, Paul J AU - Chang, Jessie C AU - Villanueva, Julie M AU - Stevens, James Y1 - 2013/11// PY - 2013 DA - Nov 2013 SP - 12433 EP - 12446 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 87 IS - 22 SN - 0022-538X, 0022-538X KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Mortality KW - Adaptations KW - Residues KW - Hemagglutinins KW - Viruses KW - Structural analysis KW - Disease control KW - Infection KW - Polysaccharides KW - Public health KW - Influenza KW - Adaptability KW - Prevention KW - Influenza virus KW - Kinetics KW - Outbreaks KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1458532613?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Virology&rft.atitle=Structural+Analysis+of+the+Hemagglutinin+from+the+Recent+2013+H7N9+Influenza+Virus&rft.au=Yang%2C+Hua%3BCarney%2C+Paul+J%3BChang%2C+Jessie+C%3BVillanueva%2C+Julie+M%3BStevens%2C+James&rft.aulast=Yang&rft.aufirst=Hua&rft.date=2013-11-01&rft.volume=87&rft.issue=22&rft.spage=12433&rft.isbn=&rft.btitle=&rft.title=Journal+of+Virology&rft.issn=0022538X&rft_id=info:doi/10.1128%2FJVI.01854-13 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-11-01 N1 - Number of references - 62 N1 - Last updated - 2015-04-02 N1 - SubjectsTermNotLitGenreText - Influenza; Adaptations; Kinetics; Hemagglutinins; Disease control; Polysaccharides; Infection; Public health; Mortality; Prevention; Adaptability; Residues; Structural analysis; Viruses; Outbreaks; Influenza virus DO - http://dx.doi.org/10.1128/JVI.01854-13 ER - TY - JOUR T1 - Characterizing risk factors for pediatric lamp oil product exposures. AN - 1443420084; 24066734 AB - Poisonings from lamp oil ingestion continue to occur worldwide among the pediatric population despite preventive measures such as restricted sale of colored and scented lamp oils. This suggests that optimal prevention practices for unintentional pediatric exposures to lamp oil have yet to be identified and/or properly implemented. To characterize demographic, health data, and potential risk factors associated with reported exposures to lamp oil by callers to poison centers (PCs) in the US and discuss their public health implications. This was a two part study in which the first part included characterizing all exposures to a lamp oil product reported to the National Poison Data System (NPDS) with regard to demographics, exposure, health, and outcome data from 1/1/2000 to 12/31/2010. Regional penetrance was calculated using NPDS data by grouping states into four regions and dividing the number of exposure calls by pediatric population per region (from the 2000 US census). Temporal analyses were performed on NPDS data by comparing number of exposures by season and around the July 4th holiday. Poisson regression was used to model the count of exposures for these analyses. In the second part of this project, in order to identify risk factors we conducted a telephone-based survey to the parents of children from five PCs in five different states. The 10 most recent lamp oil product exposure calls for each poison center were systematically selected for inclusion. Calls in which a parent or guardian witnessed a pediatric lamp oil product ingestion were eligible for inclusion. Data on demographics, exposure information, behavioral traits, and health were collected. A descriptive analysis was performed and Fisher's exact test was used to evaluate associations between variables. All analyses were conducted using SAS v9.3. Among NPDS data, 2 years was the most common patient age reported and states in the Midwestern region had the highest numbers of exposure calls compared to other regions. Exposure calls differed by season (p < 0.0001) and were higher around the July 4th holiday compared to the rest of the days in July (2.09 vs. 1.89 calls/day, p < 0.002). Most exposures occurred inside a house, were managed on-site and also had a "no effect" medical outcome. Of the 50 PC-administered surveys to parents or guardians, 39 (78%) met inclusion criteria for analysis. The majority of ingestions occurred in children that were 2 years of age, that were not alone, involved tiki torch fuel products located on a table or shelf, and occurred inside the home. The amount of lamp oil ingested did not appear to be associated with either the smell (p = 0.19) or the color of the oil (p = 1.00) in this small sample. Approximately half were asymptomatic (n = 18; 46%), and of those that reported symptoms, cough was the most common (n = 20, 95%) complaint. Lamp oil product exposures are most common among young children (around 2 years of age) while at home, not alone and likely as a result of the product being in a child-accessible location. Increasing parental awareness about potential health risks to children from these products and teaching safe storage and handling practices may help prevent both exposures and associated illness. These activities may be of greater benefit in Midwestern states and during summer months (including the period around the July 4th holiday). JF - Clinical toxicology (Philadelphia, Pa.) AU - Sheikh, S AU - Chang, A AU - Kieszak, S AU - Law, R AU - Bennett, H K W AU - Ernst, E AU - Bond, G R AU - Spiller, H A AU - Schurz-Rogers, H AU - Chu, A AU - Bronstein, A C AU - Schier, J G AD - Health Studies Branch, National Center for Environmental Health, Center for Disease Control and Prevention , Atlanta, GA , USA. Y1 - 2013/11// PY - 2013 DA - November 2013 SP - 871 EP - 878 VL - 51 IS - 9 KW - Petroleum KW - 0 KW - Abridged Index Medicus KW - Index Medicus KW - Administration, Oral KW - Respiratory Aspiration -- therapy KW - Respiratory Aspiration -- chemically induced KW - Humans KW - Cough -- therapy KW - Holidays KW - Poisson Distribution KW - Respiratory Aspiration -- epidemiology KW - Cough -- epidemiology KW - Poison Control Centers KW - Child, Preschool KW - Cough -- chemically induced KW - Infant KW - Cross-Sectional Studies KW - Risk Factors KW - Seasons KW - Administration, Inhalation KW - United States -- epidemiology KW - Female KW - Male KW - Prevalence KW - Petroleum -- toxicity KW - Accidents, Home -- prevention & control KW - Lighting UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1443420084?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+toxicology+%28Philadelphia%2C+Pa.%29&rft.atitle=Characterizing+risk+factors+for+pediatric+lamp+oil+product+exposures.&rft.au=Sheikh%2C+S%3BChang%2C+A%3BKieszak%2C+S%3BLaw%2C+R%3BBennett%2C+H+K+W%3BErnst%2C+E%3BBond%2C+G+R%3BSpiller%2C+H+A%3BSchurz-Rogers%2C+H%3BChu%2C+A%3BBronstein%2C+A+C%3BSchier%2C+J+G&rft.aulast=Sheikh&rft.aufirst=S&rft.date=2013-11-01&rft.volume=51&rft.issue=9&rft.spage=871&rft.isbn=&rft.btitle=&rft.title=Clinical+toxicology+%28Philadelphia%2C+Pa.%29&rft.issn=1556-9519&rft_id=info:doi/10.3109%2F15563650.2013.839028 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2013-12-10 N1 - Date created - 2013-10-18 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: J Popul Ther Clin Pharmacol. 2011;18:e156-60 [21471606] Clin Toxicol (Phila). 2008 Mar;46(3):222-9 [18344104] Pediatrics. 2008 Dec;122(6):1244-51 [19047241] Clin Toxicol (Phila). 2009 Jan;47(1):29-34 [19153851] J Community Health. 2010 Dec;35(6):572-8 [20195893] Clin Toxicol (Phila). 2007;45(3):304-6 [17453888] Intensive Care Med. 2001 Mar;27(3):614 [11355135] Pediatrics. 2004 Apr;113(4):e377-9 [15060272] Occup Med. 1988 Jul-Sep;3(3):555-68 [2900559] JAMA. 1997 Mar 19;277(11):885 [9062325] MMWR Morb Mortal Wkly Rep. 1998 Oct 23;47(41):880-2 [9810011] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.3109/15563650.2013.839028 ER - TY - JOUR T1 - Patients Hospitalized With Laboratory-Confirmed Influenza During the 2010-2011 Influenza Season: Exploring Disease Severity by Virus Type and Subtype AN - 1642621785; 20900269 AB - Background. The 2010-2011 influenza season was dominated by influenza A(H3N2) virus, but influenza A(H1N1) pdm09 (pH1N1) and B viruses cocirculated. This provided an opportunity to explore within-season predictors of severity among hospitalized patients, avoiding biases associated with season-to-season differences in strain virulence, population immunity, and healthcare seeking. Methods. Population-based, laboratory-confirmed influenza hospitalization surveillance data were used to examine the association between virus type/subtype and outcomes in children and adults. Multivariable analysis explored virus type/subtype, prompt antiviral treatment, medical conditions, and age as predictors for severity (intensive care unit admission or death). Results. In children, pH1N1 (adjusted odds ratio [aOR], 2.19; 95% confidence interval [CI], 1.11-4.3), chronic metabolic disease (aOR, 5.23; 95% CI, 1.74-15.69), and neuromuscular disorder (aOR, 4.84; 95% CI, 2.02-11.58) were independently associated with severity. In adults, independent predictors were pH1N1 (aOR, 2.21; 95% CI, 1.66-2.94), chronic lung disease (aOR, 1.46, 95% CI, 1.12-1.89), and neuromuscular disorder (aOR, 1.68; 95% CI, 1.11-2.52). Antiviral treatment reduced the odds of severity among adults (aOR, 0.47; 95% CI, .33-.68). Conclusions. During the 2010-2011 season, pH1N1 caused more severe disease than H3N2 or B in hospitalized patients. Underlying medical conditions increased severity despite virus strain. Antiviral treatment reduced severity among adults. Our findings underscore the importance of influenza prevention. JF - Journal of Infectious Diseases AU - Chaves, Sandra S AU - Aragon, Deborah AU - Bennett, Nancy AU - Cooper, Tara AU - D'Mello, Tiffany AU - Farley, Monica AU - Fowler, Brian AU - Hancock, Emily AU - Kirley, Pam Daily AU - Lynfield, Ruth AD - Centers for Disease Control and Prevention, schaves@cdc.gov Y1 - 2013/10/15/ PY - 2013 DA - 2013 Oct 15 SP - 1305 EP - 1314 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 208 IS - 8 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - influenza KW - influenza A(H1N1) pdm09 KW - severe influenza KW - influenza hospitalizations KW - influenza surveillance KW - Mortality KW - Age KW - Data processing KW - Metabolic disorders KW - Viruses KW - Lung diseases KW - Immunity KW - Children KW - Influenza KW - Virulence KW - Prevention KW - Health care KW - Infectious diseases KW - Intensive care units KW - Lung KW - neuromuscular system KW - Hospitals KW - H 13000:Medical Safety KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1642621785?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Patients+Hospitalized+With+Laboratory-Confirmed+Influenza+During+the+2010-2011+Influenza+Season%3A+Exploring+Disease+Severity+by+Virus+Type+and+Subtype&rft.au=Chaves%2C+Sandra+S%3BAragon%2C+Deborah%3BBennett%2C+Nancy%3BCooper%2C+Tara%3BD%27Mello%2C+Tiffany%3BFarley%2C+Monica%3BFowler%2C+Brian%3BHancock%2C+Emily%3BKirley%2C+Pam+Daily%3BLynfield%2C+Ruth&rft.aulast=Chaves&rft.aufirst=Sandra&rft.date=2013-10-15&rft.volume=208&rft.issue=8&rft.spage=1305&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjit316 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Virulence; Influenza; Age; Data processing; Intensive care units; Metabolic disorders; Lung diseases; Immunity; Children; neuromuscular system; Mortality; Prevention; Infectious diseases; Health care; Lung; Viruses; Hospitals DO - http://dx.doi.org/10.1093/infdis/jit316 ER - TY - JOUR T1 - Geographic and Temporal Trends in Antimicrobial Nonsusceptibility in Streptococcus pneumoniae in the Post-vaccine era in the United States AN - 1635014991; 20900265 AB - Background. We examined whether observed increases in antibiotic nonsusceptible nonvaccine serotypes after introduction of pneumococcal conjugate vaccine in the United States in 2000 were driven primarily by vaccine or antibiotic use. Methods. Using active surveillance data, we evaluated geographic and temporal differences in serotype distribution and within-serotype differences during 2000-2009. We compared nonsusceptibility to penicillin and erythromycin by geography after standardizing differences across time, place, and serotype by regressing standardized versus crude proportions. A regression slope (RS) approaching zero indicates greater importance of the standardizing factor. Results. Through 2000-2006, geographic differences in nonsusceptibility were better explained by within-serotype prevalence of nonsusceptibility (RS 0.32, 95% confidence interval [CI], .08-.55 for penicillin) than by geographic differences in serotype distribution (RS 0.71, 95% CI, .44-.97). From 2007-2009, serotype distribution differences became more important for penicillin (within-serotype RS 0.52, 95% CI, .11-.93; serotype distribution RS 0.57, 95% CI, .14-1.0). Conclusions. Differential nonsusceptibility, within individual serotypes, accounts for most geographic variation in nonsusceptibility, suggesting selective pressure from antibiotic use, rather than differences in serotype distribution, mainly determines nonsusceptibility patterns. Recent trends suggest geographic differences in serotype distribution may be affecting the prevalence of nonsusceptibility, possibly due to decreases in the number of nonsusceptible serotypes. JF - Journal of Infectious Diseases AU - Link-Gelles, Ruth AU - Thomas, Ann AU - Lynfield, Ruth AU - Petit, Sue AU - Schaffner, William AU - Harrison, Lee AU - Farley, Monica M AU - Aragon, Deborah AU - Nicols, Megin AU - Kirley, Pam Daily AU - Zansky, Shelley AU - Jorgensen, James AU - Juni, Billie Anne AU - Jackson, Delois AU - Moore, Matthew R AU - Lipsitch, Marc AD - Respiratory Diseases Branch, Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia; Centers of Disease Control and Prevention, 1600 Clifton Rd, Mailstop C-25, Atlanta, GA 30333, hzt7@cdc.gov Y1 - 2013/10/15/ PY - 2013 DA - 2013 Oct 15 SP - 1266 EP - 1273 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 208 IS - 8 SN - 0022-1899, 0022-1899 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology KW - antimicrobial resistance KW - erythromycin KW - invasive pneumococcal disease KW - penicillin KW - pneumococcus KW - Streptococcus pneumoniae KW - Serotypes KW - Data processing KW - Antibiotics KW - Vaccines KW - Geographical variations KW - Geography KW - Erythromycin KW - Penicillin KW - Antimicrobial agents KW - A 01340:Antibiotics & Antimicrobials KW - J 02450:Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1635014991?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Geographic+and+Temporal+Trends+in+Antimicrobial+Nonsusceptibility+in+Streptococcus+pneumoniae+in+the+Post-vaccine+era+in+the+United+States&rft.au=Link-Gelles%2C+Ruth%3BThomas%2C+Ann%3BLynfield%2C+Ruth%3BPetit%2C+Sue%3BSchaffner%2C+William%3BHarrison%2C+Lee%3BFarley%2C+Monica+M%3BAragon%2C+Deborah%3BNicols%2C+Megin%3BKirley%2C+Pam+Daily%3BZansky%2C+Shelley%3BJorgensen%2C+James%3BJuni%2C+Billie+Anne%3BJackson%2C+Delois%3BMoore%2C+Matthew+R%3BLipsitch%2C+Marc&rft.aulast=Link-Gelles&rft.aufirst=Ruth&rft.date=2013-10-15&rft.volume=208&rft.issue=8&rft.spage=1266&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjit315 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-12-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Data processing; Serotypes; Antibiotics; Geographical variations; Vaccines; Erythromycin; Geography; Penicillin; Antimicrobial agents; Streptococcus pneumoniae DO - http://dx.doi.org/10.1093/infdis/jit315 ER - TY - JOUR T1 - Biodiesel versus diesel exposure: enhanced pulmonary inflammation, oxidative stress, and differential morphological changes in the mouse lung. AN - 1435846963; 23886933 AB - The use of biodiesel (BD) or its blends with petroleum diesel (D) is considered to be a viable approach to reduce occupational and environmental exposures to particulate matter (PM). Due to its lower particulate mass emissions compared to D, use of BD is thought to alleviate adverse health effects. Considering BD fuel is mainly composed of unsaturated fatty acids, we hypothesize that BD exhaust particles could induce pronounced adverse outcomes, due to their ability to readily oxidize. The main objective of this study was to compare the effects of particles generated by engine fueled with neat BD and neat petroleum-based D. Biomarkers of tissue damage and inflammation were significantly elevated in lungs of mice exposed to BD particulates. Additionally, BD particulates caused a significant accumulation of oxidatively modified proteins and an increase in 4-hydroxynonenal. The up-regulation of inflammatory cytokines/chemokines/growth factors was higher in lungs upon BD particulate exposure. Histological evaluation of lung sections indicated presence of lymphocytic infiltrate and impaired clearance with prolonged retention of BD particulate in pigment laden macrophages. Taken together, these results clearly indicate that BD exhaust particles could exert more toxic effects compared to D. © 2013. JF - Toxicology and applied pharmacology AU - Yanamala, Naveena AU - Hatfield, Meghan K AU - Farcas, Mariana T AU - Schwegler-Berry, Diane AU - Hummer, Jon A AU - Shurin, Michael R AU - Birch, M Eileen AU - Gutkin, Dmitriy W AU - Kisin, Elena AU - Kagan, Valerian E AU - Bugarski, Aleksandar D AU - Shvedova, Anna A AD - Pathology & Physiology Research Branch/NIOSH/CDC, Morgantown, WV 26505, USA. Electronic address: wqu1@cdc.gov. Y1 - 2013/10/15/ PY - 2013 DA - 2013 Oct 15 SP - 373 EP - 383 VL - 272 IS - 2 KW - Biofuels KW - 0 KW - Cytokines KW - Gasoline KW - Particulate Matter KW - Vehicle Emissions KW - Index Medicus KW - Pulmonary toxicity KW - Lipid droplets KW - Biodiesel particle retention KW - Cytokine panel KW - Inflammation KW - Aspiration exposure KW - Bronchoalveolar Lavage Fluid -- immunology KW - Microscopy, Electron, Transmission KW - Animals KW - Cytokines -- immunology KW - Mice, Inbred C57BL KW - Lung -- ultrastructure KW - Lung -- drug effects KW - Mice KW - Lung -- metabolism KW - Bronchoalveolar Lavage Fluid -- cytology KW - Female KW - Particulate Matter -- toxicity KW - Pneumonia -- immunology KW - Pneumonia -- chemically induced KW - Vehicle Emissions -- toxicity KW - Gasoline -- toxicity KW - Oxidative Stress -- drug effects KW - Biofuels -- toxicity KW - Pneumonia -- pathology KW - Pneumonia -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1435846963?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+applied+pharmacology&rft.atitle=Biodiesel+versus+diesel+exposure%3A+enhanced+pulmonary+inflammation%2C+oxidative+stress%2C+and+differential+morphological+changes+in+the+mouse+lung.&rft.au=Yanamala%2C+Naveena%3BHatfield%2C+Meghan+K%3BFarcas%2C+Mariana+T%3BSchwegler-Berry%2C+Diane%3BHummer%2C+Jon+A%3BShurin%2C+Michael+R%3BBirch%2C+M+Eileen%3BGutkin%2C+Dmitriy+W%3BKisin%2C+Elena%3BKagan%2C+Valerian+E%3BBugarski%2C+Aleksandar+D%3BShvedova%2C+Anna+A&rft.aulast=Yanamala&rft.aufirst=Naveena&rft.date=2013-10-15&rft.volume=272&rft.issue=2&rft.spage=373&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+applied+pharmacology&rft.issn=1096-0333&rft_id=info:doi/10.1016%2Fj.taap.2013.07.006 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2013-11-26 N1 - Date created - 2013-09-23 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: J Expo Sci Environ Epidemiol. 2009 Jul;19(5):443-57 [19277070] Environ Sci Technol. 2009 May 15;43(10):3905-12 [19544906] Toxicology. 2009 Jul 28;262(1):50-6 [19463885] J Toxicol Environ Health A. 2010;73(1):41-57 [19953419] J Air Waste Manag Assoc. 2010 Feb;60(2):237-44 [20222537] J Immunol. 2010 Apr 1;184(7):3927-36 [20208007] J Lipid Res. 2010 May;51(5):945-56 [19965594] J Hazard Mater. 2010 Jul 15;179(1-3):237-43 [20307928] Int J Mol Sci. 2010;11(3):789-806 [20479986] Toxicol Sci. 2010 Jul;116(1):67-78 [20385657] Curr Opin Lipidol. 2011 Oct;22(5):335-42 [21841486] Environ Sci Technol. 2011 Oct 1;45(19):8545-51 [21842833] J Lipid Res. 2011 Nov;52(11):1865-8 [21921134] Toxicol Lett. 2012 Feb 5;208(3):262-8 [22100492] J Natl Cancer Inst. 2012 Jun 6;104(11):855-68 [22393209] N Engl J Med. 2007 Sep 13;357(11):1075-82 [17855668] Circulation. 2005 Dec 20;112(25):3930-6 [16365212] Science. 2006 Jan 27;311(5760):435 [16439624] Science. 2006 Jan 27;311(5760):484-9 [16439654] Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11206-10 [16837571] Am J Physiol Lung Cell Mol Physiol. 2007 Mar;292(3):L664-70 [17085524] Environ Health Perspect. 2007 Apr;115(4):496-9 [17450214] Arch Toxicol. 2007 Aug;81(8):599-603 [17375286] Am J Respir Crit Care Med. 2007 Aug 15;176(4):395-400 [17446340] J Immunol. 2000 Aug 15;165(4):1877-81 [10925267] Chest. 2000 Aug;118(2):503-8 [10936147] Ann Occup Hyg. 2000 Sep;44(6):435-47 [10963708] Inhal Toxicol. 2002 Oct;14(10):1017-48 [12396409] J Biol Chem. 2002 Dec 20;277(51):49965-75 [12376550] Mutagenesis. 2000 Sep;15(5):391-7 [10970444] J Exp Med. 2000 Sep 18;192(6):823-33 [10993913] J Nutr. 2000 Dec;130(12):3028-33 [11110863] Front Biosci. 2001 Mar 1;6:D429-55 [11229875] Adv Immunol. 2001;79:55-92 [11680011] Am J Respir Cell Mol Biol. 2001 Oct;25(4):515-21 [11694458] Am J Respir Cell Mol Biol. 2002 Feb;26(2):202-8 [11804871] Inhal Toxicol. 2010 Dec;22 Suppl 2:59-69 [21029033] Environ Sci Technol. 2010 Nov 1;44(21):8343-9 [20886845] Appl Occup Environ Hyg. 2002 Jun;17(6):400-5 [12049428] J Histochem Cytochem. 2011 May;59(5):540-56 [21430261] Environ Health Perspect. 2011 Jul;119(7):951-7 [21377951] J Clin Endocrinol Metab. 2011 Jul;96(7):E1083-91 [21525163] J Immunol. 2002 Jul 1;169(1):487-99 [12077280] Res Rep Health Eff Inst. 2003 Dec;(112):1-30; discussion 51-67 [14738208] Res Rep Health Eff Inst. 2003 Dec;(112):31-50; discussion 51-67 [14738209] Crit Rev Toxicol. 1986;17(1):23-60 [2427276] Analyst. 1996 Sep;121(9):1183-90 [8831275] Toxicol Sci. 1998 Feb;41(2):209-16 [9520357] Analyst. 1998 May;123(5):851-7 [9709478] Mutat Res. 1998 Jul 8;415(1-2):13-23 [9711258] Science. 1998 Dec 18;282(5397):2258-61 [9856949] Environ Health Perspect. 2004 Nov;112(15):1539-43 [15531439] Toxicol Sci. 2005 Jun;85(2):898-905 [15746007] Chemosphere. 2007 Nov;70(1):13-9 [17767946] Immunol Cell Biol. 2007 Nov-Dec;85(8):617-22 [17680010] Curr Drug Targets. 2007 Dec;8(12):1249-63 [18220702] Am J Respir Cell Mol Biol. 2008 May;38(5):532-40 [18079490] Environ Res. 2008 Jun;107(2):178-84 [18329013] Histochem Cell Biol. 2008 Aug;130(2):263-79 [18546013] Am J Respir Cell Mol Biol. 2008 Nov;39(5):560-8 [18483420] J Hypertens. 2009 Jun;27(6):1293-302 [19462499] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1016/j.taap.2013.07.006 ER - TY - JOUR T1 - Modeling the Effect of Water, Sanitation, and Hygiene and Oral Cholera Vaccine Implementation in Haiti AN - 1647023931; 21172243 AB - In 2010, toxigenic Vibrio cholerae was newly introduced to Haiti. Because resources are limited, decision-makers need to understand the effect of different preventive interventions. We built a static model to estimate the potential number of cholera cases averted through improvements in coverage in water, sanitation and hygiene (WASH) (i.e., latrines, point-of-use chlorination, and piped water), oral cholera vaccine (OCV), or a combination of both. We allowed indirect effects and non-linear relationships between effect and population coverage. Because there are limited incidence data for endemic cholera in Haiti, we estimated the incidence of cholera over 20 years in Haiti by using data from Malawi. Over the next two decades, scalable WASH interventions could avert 57,949-78,567 cholera cases, OCV could avert 38,569-77,636 cases, and interventions that combined WASH and OCV could avert 71,586-88,974 cases. Rate of implementation is the most influential variable, and combined approaches maximized the effect. JF - American Journal of Tropical Medicine and Hygiene AU - Chun-Hai, Isaac AU - Fitter, David L AU - Borse, Rebekah H AU - Meltzer, Martin I AU - Tappero, Jordan W AD - National Center for Emerging and Zoonotic Infectious Diseases, and Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, jwt0@cdc.gov Y1 - 2013/10// PY - 2013 DA - October 2013 SP - 633 EP - 640 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 89 IS - 4 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts KW - Disease control KW - Intervention KW - Models KW - Endemic species KW - Sanitation KW - Water treatment KW - Cholera KW - Malawi KW - ASW, Caribbean Sea, Greater Antilles, Haiti KW - Modelling KW - Data processing KW - Pathogenic bacteria KW - Bacterial diseases KW - Vibrio cholerae KW - Chlorination KW - Vaccines KW - Hygiene KW - K 03490:Miscellaneous KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms KW - H 4000:Food and Drugs KW - J 02450:Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1647023931?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Modeling+the+Effect+of+Water%2C+Sanitation%2C+and+Hygiene+and+Oral+Cholera+Vaccine+Implementation+in+Haiti&rft.au=Chun-Hai%2C+Isaac%3BFitter%2C+David+L%3BBorse%2C+Rebekah+H%3BMeltzer%2C+Martin+I%3BTappero%2C+Jordan+W&rft.aulast=Chun-Hai&rft.aufirst=Isaac&rft.date=2013-10-01&rft.volume=89&rft.issue=4&rft.spage=633&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.13-0201 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Endemic species; Pathogenic bacteria; Bacterial diseases; Disease control; Chlorination; Vaccines; Hygiene; Modelling; Sanitation; Data processing; Cholera; Models; Water treatment; Intervention; Vibrio cholerae; Malawi; ASW, Caribbean Sea, Greater Antilles, Haiti DO - http://dx.doi.org/10.4269/ajtmh.13-0201 ER - TY - JOUR T1 - Access to Safe Water in Rural Artibonite, Haiti 16 Months after the Onset of the Cholera Epidemic AN - 1647023861; 21172245 AB - Haiti has the lowest improved water and sanitation coverage in the Western Hemisphere and is suffering from the largest cholera epidemic on record. In May of 2012, an assessment was conducted in rural areas of the Artibonite Department to describe the type and quality of water sources and determine knowledge, access, and use of household water treatment products to inform future programs. It was conducted after emergency response was scaled back but before longer-term water, sanitation, and hygiene activities were initiated. The household survey and source water quality analysis documented low access to safe water, with only 42.3% of households using an improved drinking water source. One-half (50.9%) of the improved water sources tested positive for Escherichia coli. Of households with water to test, 12.7% had positive chlorine residual. The assessment reinforces the identified need for major investments in safe water and sanitation infrastructure and the importance of household water treatment to improve access to safe water in the near term. JF - American Journal of Tropical Medicine and Hygiene AU - Patrick, Molly AU - Berendes, David AU - Murphy, Jennifer AU - Bertrand, Fabienne AU - Husain, Farah AU - Handzel, Thomas AD - Emergency Response and Recovery Branch, Division of Global Health Protection, Centers for Disease Control and Prevention, 4770 Buford Highway, MS-F57, Atlanta, GA 30341; Waterborne Disease Prevention Branch, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia; Direction Nationale de l'Eau Potable et de l'Assainissement, Port-au-Prince, Haiti, vej7@cdc.gov Y1 - 2013/10// PY - 2013 DA - October 2013 SP - 647 EP - 653 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 89 IS - 4 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Epidemics KW - Pathogenic bacteria KW - Bacterial diseases KW - Chlorine KW - Water quality KW - Sanitation KW - Drinking Water KW - Water treatment KW - Escherichia coli KW - Emergencies KW - Cholera KW - Drinking water KW - Hygiene KW - ASW, Caribbean Sea, Greater Antilles, Haiti KW - Q1 08484:Species interactions: parasites and diseases KW - K 03450:Ecology KW - Q5 08524:Public health, medicines, dangerous organisms KW - J 02450:Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1647023861?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Access+to+Safe+Water+in+Rural+Artibonite%2C+Haiti+16+Months+after+the+Onset+of+the+Cholera+Epidemic&rft.au=Patrick%2C+Molly%3BBerendes%2C+David%3BMurphy%2C+Jennifer%3BBertrand%2C+Fabienne%3BHusain%2C+Farah%3BHandzel%2C+Thomas&rft.aulast=Patrick&rft.aufirst=Molly&rft.date=2013-10-01&rft.volume=89&rft.issue=4&rft.spage=647&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.13-0308 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Drinking Water; Epidemics; Water treatment; Pathogenic bacteria; Bacterial diseases; Emergencies; Water quality; Hygiene; Sanitation; Chlorine; Cholera; Drinking water; Escherichia coli; ASW, Caribbean Sea, Greater Antilles, Haiti DO - http://dx.doi.org/10.4269/ajtmh.13-0308 ER - TY - JOUR T1 - Maternal prepregnancy weight status and associations with children's development and disabilities at kindergarten AN - 1554943053; 20501258 AB - Objective: Obesity is prevalent among women of reproductive age, and developmental disabilities in children continue to increase. We examined associations between mother's prepregnancy body mass index (BMI) and physical and developmental disabilities, and objective measures of reading and math skills and fine and gross motor function in children. Methods: We used the Early Childhood Longitudinal Study-Birth Cohort (ECLS-B; n=5200), a cohort of children born in 2001 and followed until kindergarten. Children were classified according to maternal prepregnancy BMI (in kg per m super(2)): underweight (BMI <18.5), normal weight (BMI 18.5-24.9), overweight (BMI 25.0-29.9), obese class I (BMI 30.0-34.9) and obese class II/III (BMI greater than or equal to 35.0). Parent reports of doctor-diagnosed disabilities were collected up to kindergarten and classified as learning and behavioral or physical. Children's reading and math and fine and gross motor function were assessed at kindergarten according to standardized tests. Linear and modified logistic regression models were adjusted for maternal sociodemographic variables, family enrichment variables, and children's sex, age and year of kindergarten entry. Additional adjustment for current child BMI was performed in separate models. All data are weighted to be nationally representative of the children born in 2001. Results: Compared with children of normal-weight mothers, children born to obese class II/III mothers had an increased risk of learning or behavioral (risk ratio 1.67; 95% confidence interval 1.27, 2.21)), but not physical disabilities (risk ratio 0.57; 95% confidence interval 0.27, 1.22). Gross (P<0.001), but not fine (P=0.06) motor function was significantly associated with maternal BMI, but gross motor function was attenuated after adjustment for current child BMI (P=0.05). Children's reading scores (P=0.01) but not math scores (P=0.11) were significantly associated with maternal BMI. Conclusions: In this nationally representative US cohort, children born to severely obese mothers had an increased risk for diagnosed learning and behavioral but not physical disabilities by kindergarten. JF - International Journal of Obesity AU - Hinkle, S N AU - Sharma, A J AU - Kim, S Y AU - Schieve, L A AD - Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA Y1 - 2013/10// PY - 2013 DA - Oct 2013 SP - 1344 EP - 1351 PB - Nature Publishing Group, The Macmillan Building London N1 9XW United Kingdom VL - 37 IS - 10 SN - 0307-0565, 0307-0565 KW - Risk Abstracts KW - Risk assessment KW - Obesity KW - Age KW - Disabilities KW - Body mass KW - Risk taking KW - Standards KW - Children KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1554943053?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Obesity&rft.atitle=Maternal+prepregnancy+weight+status+and+associations+with+children%27s+development+and+disabilities+at+kindergarten&rft.au=Hinkle%2C+S+N%3BSharma%2C+A+J%3BKim%2C+S+Y%3BSchieve%2C+L+A&rft.aulast=Hinkle&rft.aufirst=S&rft.date=2013-10-01&rft.volume=37&rft.issue=10&rft.spage=1344&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Obesity&rft.issn=03070565&rft_id=info:doi/10.1038%2Fijo.2013.128 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-08-01 N1 - Last updated - 2014-09-05 N1 - SubjectsTermNotLitGenreText - Risk assessment; Obesity; Age; Body mass; Disabilities; Risk taking; Standards; Children DO - http://dx.doi.org/10.1038/ijo.2013.128 ER - TY - JOUR T1 - Use of reservoir simulation and in-mine ventilation measurements to estimate coal seam properties AN - 1475561324; 18815143 AB - Methane is a safety concern in underground coal mines. In its explosive range of 5%-15% in air, methane can be easily ignited in the presence of an ignition source to create a violent methane explosion. Ventilation is the main control mechanism to keep methane levels below the explosive limit. However, effectiveness of a ventilation system is dependent on multiple factors such as geological conditions, mine design, and reservoir properties of the coal seam. Without good knowledge of these factors, methane emissions can still create a localized zone of high methane concentrations in areas of low air velocities and quantities, and can render the ventilation system ineffective. Among those factors controlling methane emissions, reservoir properties of the coal seam are particularly important, especially if the mined seam is the main source of methane, with the properties of the coal controlling methane storage and emission potential during mining operations. JF - International Journal of Rock Mechanics and Mining Sciences AU - Erdogan, S S AU - Karacan, COe AU - Okandan, E AD - NIOSH, Office of Mine Safety and Health Research, Pittsburgh, USA, cok6@cdc.gov Y1 - 2013/10// PY - 2013 DA - October 2013 SP - 148 EP - 158 PB - Elsevier B.V., P.O. Box 800 Kidlington Oxford OX5 1DX United Kingdom VL - 63 SN - 1365-1609, 1365-1609 KW - Water Resources Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources KW - Methane KW - Reservoir KW - Ventilation KW - Velocity KW - Coal KW - Explosions KW - Rock Mechanics KW - Rock mechanics KW - Explosives KW - Coal Mines KW - Mining KW - Reservoirs KW - Q2 09422:Storage and transport KW - SW 0810:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1475561324?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Rock+Mechanics+and+Mining+Sciences&rft.atitle=Use+of+reservoir+simulation+and+in-mine+ventilation+measurements+to+estimate+coal+seam+properties&rft.au=Erdogan%2C+S+S%3BKaracan%2C+COe%3BOkandan%2C+E&rft.aulast=Erdogan&rft.aufirst=S&rft.date=2013-10-01&rft.volume=63&rft.issue=&rft.spage=148&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Rock+Mechanics+and+Mining+Sciences&rft.issn=13651609&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-12-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Reservoir; Methane; Rock mechanics; Mining; Coal; Explosions; Rock Mechanics; Ventilation; Velocity; Coal Mines; Explosives; Reservoirs ER - TY - JOUR T1 - Systematic review of human listeriosis in China, 1964-2010 AN - 1468349820; 18739555 AB - Listeria is an important foodborne pathogen with severe manifestations and high case-fatality rate. However, listeriosis is not yet a notifiable disease in China, and there is no national monitoring system for cases. We conducted a systematic review to better understand the clinical and epidemiologic features of listeriosis in China. Both electronic and manual retrieval systems were used to search Chinese literature for cases and isolates of human listeriosis reported between 1964 and 2010. We recorded and analysed demographic, clinical and laboratory information available for reported cases. A total of 147 clinical cases, 479 Listeria isolates and 82 outbreak-related cases were reported in 28 (90%) provinces in China from January 1964 to December 2010. Of the clinical cases, 45 (31%) were central nervous system infections, 68 (46%) were septicaemia and 34 (23%) were focal infections or gastroenteritis. The overall case-fatality rate was 26% (34/130) among clinical cases with known outcomes and 46% (21/46) among neonatal cases. Listeriosis cases occurred in China throughout the study period between 1964 and 2010. Case-fatality was similar to published data from other countries. China should consider requiring notification of listeriosis cases to improve estimates of incidence, identification of risk factors and design of preventive measures.Original Abstract: Listeria est un pathogene important d'origine alimentaire avec des manifestations graves et un taux de letalite eleve. Cependant, la listeriose n'est pas toujours pas une maladie a declaration obligatoire en Chine et il n'existe pas de systeme national de surveillance des cas. Nous avons effectue une revue systematique pour mieux comprendre les caracteristiques cliniques et epidemiologiques de la listeriose en Chine. Les systemes de recherche electroniques et manuels ont ete tous deux utilises pour rechercher la litterature chinoise pour les cas et isolats de listeriose humaine signales entre 1964 et 2010. Nous avons enregistre et analyse les informations demographiques, cliniques et de laboratoires disponibles pour les cas rapportes. Au total 147 cas cliniques, 479 isolats de Listeria et 82 cas lies a une epidemie ont ete signales dans 28 (90%) provinces en Chine entre janvier 1964 et decembre 2010. Parmi les cas cliniques, 45 (31%) etaient des infections du systeme nerveux central, 68 (46%) etaient des septicemies et 34 (23%) etaient des infections focales ou des gastro-enterites. Le taux global de letalite etait de 26% (34/130) parmi les cas cliniques avec des resultats connus et 46% (21/46) parmi les cas neonataux. Les cas de listeriose sont survenus en Chine tout au long de la periode d'etude entre 1964 et 2010. La letalite etait similaire a celle des donnees publiees dans d'autres pays. La Chine devrait envisager d'exiger la notification des cas de listeriose afin d'ameliorer les estimations de l'incidence, l'identification des facteurs de risque et la conception de mesures preventives. La Listeria es un importante patogeno transmitido por alimentos con manifestaciones graves y una alta tasa de mortalidad. Sin embargo, la listeriosis aun no es una enfermedad de notificacion obligatoria en China, y no hay un sistema nacional de monitorizacion para los casos. Hemos realizado una revision sistematica para entender mejor las caracteristicas clinicas y epidemiologicas de la listeriosis in China. Se utilizaron sistemas de recuperacion tanto electronicos como manuales para buscar literatura sobre casos y cepas aisladas en China de listeriosis humana, reportados entre 1964 y 2010. Recogimos y analizamos la informacion disponible sobre datos demograficos, clinicos y de laboratorio de casos reportados. Un total de 147 casos clinicos, 479 cepas de Listeria y 82 casos relacionados con un brote epidemico fueron reportados en 28 (90%) provincias de China entre Enero de 1964 y Diciembre 2010. De los casos clinicos 45 (31%) eran infecciones del sistema nervioso central, 68 (46%) eran septicemia y 34 (23%) eran infecciones localizadas o gastroenteritis. La tasa de letalidad era del 26% (34/130) entre los casos clinicos con resultado conocido y del 46% (21/46) entre los casos de neonatos. A lo largo de todo el periodo de estudio, entre 1964 y 2010, se dieron casos de listeriosis en China. La tasa de letalidad era similar a los datos publicados para otros paises. China deberia considerar implantar la notificacion obligatoria para los casos de listeriosis con el fin de mejorar los calculos de incidencia, identificacion de factores de riesgo y el diseno de medidas de prevencion. JF - Tropical Medicine and International Health AU - Feng, Yanfang AU - Wu, Shuyu AU - Varma, Jay K AU - Klena, John D AU - Angulo, Frederick J AU - Ran, Lu AD - Division of Infectious Disease Chinese Center for Disease Control and Prevention. Key Laboratory of Surveillance and Early-warning on Infectious Disease Y1 - 2013/10// PY - 2013 DA - Oct 2013 SP - 1248 EP - 1256 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 18 IS - 10 SN - 1360-2276, 1360-2276 KW - Microbiology Abstracts B: Bacteriology KW - Demography KW - Central nervous system KW - Data processing KW - Listeriosis KW - Risk factors KW - Food KW - Neonates KW - Pathogens KW - Infection KW - Gastroenteritis KW - Listeria KW - J 02310:Genetics & Taxonomy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1468349820?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Tropical+Medicine+and+International+Health&rft.atitle=Systematic+review+of+human+listeriosis+in+China%2C+1964-2010&rft.au=Feng%2C+Yanfang%3BWu%2C+Shuyu%3BVarma%2C+Jay+K%3BKlena%2C+John+D%3BAngulo%2C+Frederick+J%3BRan%2C+Lu&rft.aulast=Feng&rft.aufirst=Yanfang&rft.date=2013-10-01&rft.volume=18&rft.issue=10&rft.spage=1248&rft.isbn=&rft.btitle=&rft.title=Tropical+Medicine+and+International+Health&rft.issn=13602276&rft_id=info:doi/10.1111%2Ftmi.12173 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-12-01 N1 - Last updated - 2013-12-16 N1 - SubjectsTermNotLitGenreText - Demography; Central nervous system; Data processing; Listeriosis; Food; Risk factors; Pathogens; Neonates; Gastroenteritis; Infection; Listeria DO - http://dx.doi.org/10.1111/tmi.12173 ER - TY - JOUR T1 - Genetic diversity of antigens Rv2945c and Rv0309 in Mycobacterium tuberculosis strains may reflect ongoing immune evasion AN - 1464510334; 18737225 AB - Host immune pressure and associated immune evasion of pathogenic bacteria are key features of host-pathogen co-evolution. A previous study showed that human T-cell epitopes of Mycobacterium tuberculosis are evolutionarily hyperconserved and thus it was deduced that M. tuberculosis lacks antigenic variation and immune evasion. Here, we selected 173 clinical M. tuberculosis complex (MTBC) isolates from China, amplified the genes encoding Rv2945c and Rv0309, and compared the sequences. The results showed that genetic diversity existed in these two genes among the MTBC strains and two single nucleotide polymorphisms (SNPs) presented higher polymorphisms. Antigen Rv2945c harbored a higher number of amino acid substitutions of its T-cell epitopes, which may reflect ongoing immune evasion. In addition, the high dN/dS value of Rv0309 suggested antigen Rv0309 might be involved in diversifying selection to evade host immunity. Finally, a small group of strains were identified based on the genetic diversity of these two genes, which might indicate that they interact differently with human T cells compared with other strains. JF - FEMS Microbiology Letters AU - Jiang, Yi AU - Dou, Xiangfeng AU - Zhang, Wen AU - Liu, Haican AU - Zhao, Xiuqin AU - Wang, Haiyin AU - Lian, Lulu AU - Yu, Qin AU - Zhang, Jingrui AU - Li, Guilian AU - Chen, Chen AU - Wan, Kanglin AD - National Institute for Communicable Disease Control and PreventionChinese Center for Disease Control and Prevention/State Key Laboratory for Infectious Disease Prevention and Control Y1 - 2013/10// PY - 2013 DA - Oct 2013 SP - 77 EP - 82 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 347 IS - 1 SN - 0378-1097, 0378-1097 KW - Genetics Abstracts; Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Amino acid substitution KW - Single-nucleotide polymorphism KW - Gene polymorphism KW - Lymphocytes T KW - Genetic diversity KW - Tuberculosis KW - Pressure KW - Epitopes KW - Evolution KW - Mycobacterium tuberculosis KW - J 02350:Immunology KW - F 06910:Microorganisms & Parasites KW - G 07770:Bacteria UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1464510334?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=FEMS+Microbiology+Letters&rft.atitle=Genetic+diversity+of+antigens+Rv2945c+and+Rv0309+in+Mycobacterium+tuberculosis+strains+may+reflect+ongoing+immune+evasion&rft.au=Jiang%2C+Yi%3BDou%2C+Xiangfeng%3BZhang%2C+Wen%3BLiu%2C+Haican%3BZhao%2C+Xiuqin%3BWang%2C+Haiyin%3BLian%2C+Lulu%3BYu%2C+Qin%3BZhang%2C+Jingrui%3BLi%2C+Guilian%3BChen%2C+Chen%3BWan%2C+Kanglin&rft.aulast=Jiang&rft.aufirst=Yi&rft.date=2013-10-01&rft.volume=347&rft.issue=1&rft.spage=77&rft.isbn=&rft.btitle=&rft.title=FEMS+Microbiology+Letters&rft.issn=03781097&rft_id=info:doi/10.1111%2F1574-6968.12222 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-11-01 N1 - Number of references - 15 N1 - Last updated - 2014-05-29 N1 - SubjectsTermNotLitGenreText - Amino acid substitution; Single-nucleotide polymorphism; Gene polymorphism; Lymphocytes T; Genetic diversity; Tuberculosis; Pressure; Evolution; Epitopes; Mycobacterium tuberculosis DO - http://dx.doi.org/10.1111/1574-6968.12222 ER - TY - JOUR T1 - Cutaneous Infection Caused by a Novel Francisella sp. AN - 1448216216; 18651613 AB - A 69-year-old patient presented with a tender, thickly crusted skin lesion of 1 week's duration. A bacterial culture swab taken from the underlying granular tissue yielded a pure isolate of a Gram-negative coccobacillus, presumptively identified as a novel Francisella species via 16S rRNA and multilocus gene sequence analysis. JF - Journal of Clinical Microbiology AU - Respicio-Kingry, Laurel B AU - Byrd, Lori AU - Allison, Ashley AU - Brett, Meghan AU - Scott-Waldron, Christine AU - Galliher, Karen AU - Hannah, Paul AU - Mead, Paul AU - Petersen, Jeannine M Y1 - 2013/10// PY - 2013 DA - October 2013 SP - 3456 EP - 3460 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 51 IS - 10 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Skin diseases KW - Francisella KW - Infection KW - rRNA 16S KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1448216216?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Cutaneous+Infection+Caused+by+a+Novel+Francisella+sp.&rft.au=Respicio-Kingry%2C+Laurel+B%3BByrd%2C+Lori%3BAllison%2C+Ashley%3BBrett%2C+Meghan%3BScott-Waldron%2C+Christine%3BGalliher%2C+Karen%3BHannah%2C+Paul%3BMead%2C+Paul%3BPetersen%2C+Jeannine+M&rft.aulast=Respicio-Kingry&rft.aufirst=Laurel&rft.date=2013-10-01&rft.volume=51&rft.issue=10&rft.spage=3456&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.01105-13 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-10-01 N1 - Number of references - 18 N1 - Last updated - 2016-07-20 N1 - SubjectsTermNotLitGenreText - Skin diseases; Infection; rRNA 16S; Francisella DO - http://dx.doi.org/10.1128/JCM.01105-13 ER - TY - JOUR T1 - Hospitalizations, costs, and mortality among infants with critical congenital heart disease: how important is timely detection? AN - 1443995066; 24000201 AB - Critical congenital heart disease (CCHD) was recently added to the U.S. Recommended Uniform Screening Panel for newborns. States considering screening requirements may want more information about the potential impact of screening. This study examined potentially avoidable mortality among infants with late detected CCHD and assessed whether late detection was associated with increased hospital resource use during infancy. This was a state-wide, population-based, observational study of infants with CCHD (n = 3603) born 1998 to 2007 identified by the Florida Birth Defects Registry. We examined 12 CCHD conditions that are targets of newborn screening. Late detection was defined as CCHD diagnosis after the birth hospitalization. Deaths potentially avoidable through screening were defined as those that occurred outside a hospital following birth hospitalization discharge and those that occurred within 3 days of an emergency readmission. For 23% (n = 825) of infants, CCHD was not detected during the birth hospitalization. Death occurred among 20% (n = 568/2,778) of infants with timely detected CCHD and 8% (n = 66/825) of infants with late detected CCHD, unadjusted for clinical characteristics. Potentially preventable deaths occurred in 1.8% (n = 15/825) of infants with late detected CCHD (0.4% of all infants with CCHD). In multivariable models adjusted for selected characteristics, late CCHD detection was significantly associated with 52% more admissions, 18% more hospitalized days, and 35% higher inpatient costs during infancy. Increased CCHD detection at birth hospitals through screening may lead to decreased hospital costs and avoid some deaths during infancy. Additional studies conducted after screening implementation are needed to confirm these findings. Copyright © 2013 Wiley Periodicals, Inc. JF - Birth defects research. Part A, Clinical and molecular teratology AU - Peterson, Cora AU - Dawson, April AU - Grosse, Scott D AU - Riehle-Colarusso, Tiffany AU - Olney, Richard S AU - Tanner, Jean Paul AU - Kirby, Russell S AU - Correia, Jane A AU - Watkins, Sharon M AU - Cassell, Cynthia H AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia. Y1 - 2013/10// PY - 2013 DA - October 2013 SP - 664 EP - 672 VL - 97 IS - 10 KW - Index Medicus KW - congenital KW - pediatrics KW - birth defects surveillance KW - costs and cost analysis KW - heart defects KW - Infant KW - Critical Illness KW - Humans KW - Cost-Benefit Analysis KW - Retrospective Studies KW - Infant, Newborn KW - Hospital Costs KW - Neonatal Screening -- organization & administration KW - Delayed Diagnosis KW - Survival Analysis KW - Florida -- epidemiology KW - Registries KW - Heart Defects, Congenital -- economics KW - Heart Defects, Congenital -- epidemiology KW - Hospitalization -- economics KW - Heart Defects, Congenital -- mortality KW - Hospitalization -- statistics & numerical data KW - Heart Defects, Congenital -- diagnosis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1443995066?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Birth+defects+research.+Part+A%2C+Clinical+and+molecular+teratology&rft.atitle=Hospitalizations%2C+costs%2C+and+mortality+among+infants+with+critical+congenital+heart+disease%3A+how+important+is+timely+detection%3F&rft.au=Peterson%2C+Cora%3BDawson%2C+April%3BGrosse%2C+Scott+D%3BRiehle-Colarusso%2C+Tiffany%3BOlney%2C+Richard+S%3BTanner%2C+Jean+Paul%3BKirby%2C+Russell+S%3BCorreia%2C+Jane+A%3BWatkins%2C+Sharon+M%3BCassell%2C+Cynthia+H&rft.aulast=Peterson&rft.aufirst=Cora&rft.date=2013-10-01&rft.volume=97&rft.issue=10&rft.spage=664&rft.isbn=&rft.btitle=&rft.title=Birth+defects+research.+Part+A%2C+Clinical+and+molecular+teratology&rft.issn=1542-0760&rft_id=info:doi/10.1002%2Fbdra.23165 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2014-06-03 N1 - Date created - 2013-10-21 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Pediatrics. 2004 Nov;114(5):1341-7 [15520119] Pediatrics. 2013 May;131(5):e1502-8 [23610203] Health Technol Assess. 2005 Nov;9(44):1-152, iii-iv [16297355] Postgrad Med J. 2006 Jul;82(969):468-70 [16822925] Acta Paediatr. 2007 Aug;96(8):1146-9 [17590190] BMJ. 2009;338:a3037 [19131383] Cardiol Young. 2008 Dec;18 Suppl 2:92-100 [19063779] Arch Pediatr Adolesc Med. 2008 Oct;162(10):969-74 [18838650] BMC Pediatr. 2009;9:32 [19426556] J Pediatr. 2009 Jul;155(1):26-31, 31.e1 [19394031] Circulation. 2009 Aug 4;120(5):447-58 [19581492] Natl Vital Stat Rep. 2010 Mar 3;58(11):1-14, 16 [20575315] Congenit Heart Dis. 2010 May-Jun;5(3):292-6 [20576049] Arch Dis Child. 2012 Mar;97(3):221-6 [22247242] Natl Vital Stat Rep. 2011 Nov 3;60(1):1-70 [22670489] Public Health Rep. 2012 Jul-Aug;127(4):391-400 [22753982] MMWR Morb Mortal Wkly Rep. 2012 Oct 26;61(42):849-53 [23095953] Birth Defects Res A Clin Mol Teratol. 2010 Dec;88(12):1017-22 [20842648] Pediatrics. 2011 Nov;128(5):e1259-67 [21987707] J Registry Manag. 2011 Spring;38(1):30-8 [22097703] Pediatrics. 2012 Jan;129(1):190-2 [22201143] Health Technol Assess. 2012;16(2):v-xiii, 1-184 [22284744] Heart. 2012 Nov;98(22):1667-73 [22888161] Birth Defects Res A Clin Mol Teratol. 2012 Dec;94(12):965-9 [23184496] J Perinatol. 2005 Nov;25(11):737-42 [16163368] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1002/bdra.23165 ER - TY - JOUR T1 - Uptake and effectiveness of monovalent influenza A (H1N1) pandemic 2009 vaccine among healthcare personnel in Kenya, 2010 AN - 1464507827; 18807215 AB - Introduction: During April-June 2010, the Kenya Ministry of Public Health and Sanitation distributed free monovalent influenza A(H1N1)pdm09 vaccines to health care personnel (HCP) and other vulnerable groups. We conducted a prospective, cohort study among HCP to characterize influenza A(H1N1)pdm09 vaccine uptake, and to assess influenza A(H1N1)pdm09 vaccine effectiveness. Methods: We enrolled HCP from 5 hospitals and followed them for 6 months. At enrollment, we asked HCP if they had received the influenza A(H1N1)pdm09 vaccine and their reasons for their decision. We administered weekly questionnaires to participants about respiratory symptoms suffered during the previous week. Participants who had acute respiratory illness were asked to contact our surveillance clinician, and nasopharyngeal and oropharyngeal specimens were collected and later tested for influenza by real-time reverse-transcriptase polymerase-chain-reaction. Vaccine effectiveness was estimated by comparing the incidence of acute respiratory illness, absenteeism from work due to respiratory illness and laboratory-confirmed influenza among vaccinated and unvaccinated HCP. Results: We enrolled 3803 HCP from the five hospitals; 64% received influenza vaccine. Vaccinated HCP were more likely to develop acute respiratory illness (ARI) and more likely to report missed days of work due to respiratory illness compared to non-vaccinated HCP (adjusted incidence rate ratio (aIRR) 1.50, 95% confidence intervals (CI): 1.33-1.70) and (aIRR 2.02, 95% CI: 1.41-2.88), respectively. Of 531 samples collected from vaccinated and non-vaccinated HCP, 30 were influenza A and 3 were influenza B. Two influenza A(H1N1)pdm09 subtypes were isolated; one from vaccinated and the other from non-vaccinated HCP. Discussion and conclusions: A majority of Kenyan HCP surveyed reported receiving the influenza A(H1N1)pdm09 vaccine. Because of low circulation of influenza A(H1N1)pdm09 virus during the study period, vaccine effectiveness could not be determined. The findings of increased ARI events and missed days of work among vaccinated HCP were likely confounded by vaccine-seeking behavioral factors. JF - Vaccine AU - Njuguna, H AU - Ahmed, J AU - Oria, P A AU - Arunga, G AU - Williamson, J AU - Kosgey, A AU - Muthoka, P AU - Mott, JA AU - Breiman, R F AU - Katz, MA AD - KEMRI-CDC, Nairobi Kenya, 606, 00621 Village Market, Nairobi, Kenya, hnjuguna@ke.cdc.gov Y1 - 2013/09/23/ PY - 2013 DA - 2013 Sep 23 SP - 4662 EP - 4667 VL - 31 IS - 41 SN - 0264-410X, 0264-410X KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts; Immunology Abstracts KW - Health care KW - Influenza KW - Kenya KW - Vaccines KW - F 06905:Vaccines KW - H 1000:Occupational Safety and Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1464507827?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Uptake+and+effectiveness+of+monovalent+influenza+A+%28H1N1%29+pandemic+2009+vaccine+among+healthcare+personnel+in+Kenya%2C+2010&rft.au=Njuguna%2C+H%3BAhmed%2C+J%3BOria%2C+P+A%3BArunga%2C+G%3BWilliamson%2C+J%3BKosgey%2C+A%3BMuthoka%2C+P%3BMott%2C+JA%3BBreiman%2C+R+F%3BKatz%2C+MA&rft.aulast=Njuguna&rft.aufirst=H&rft.date=2013-09-23&rft.volume=31&rft.issue=41&rft.spage=4662&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-11-01 N1 - Last updated - 2014-03-20 N1 - SubjectsTermNotLitGenreText - Vaccines; Influenza; Kenya ER - TY - JOUR T1 - Differences in access to healthcare and utilisation of HIV and sexually transmissible infection services between men who have sex with men and men who have sex only with women: results of the 2006-10 National Survey of Family Growth in the United States AN - 1463071819; 201326569 AB - Background: Men who have sex with men (MSM) experience disparities in access to healthcare and have specific healthcare needs. Methods: We analysed data from the 2006-10 National Survey of Family Growth (NSFG) to examine differences in access to healthcare and HIV and sexually transmissible infection (STI) related health services by MSM and non-MSM among men in the United States aged 15-44 years who have ever had sex. MSM and sexually active MSM were identified in the NSFG as men who had ever had oral or anal sex with another man, or who had sex in the past 12 months with another man, respectively. Access was measured by the type of health insurance, having a usual place for receiving healthcare and type of usual place. Results: Of men aged 15-44 years who have ever had sex, there were no significant differences between MSM and non-MSM in the three access measures. MSM were more likely than non-MSM to receive HIV counselling (22.5% v. 8.3%) and STI testing (26.2% v. 15.6%) in the past 12 months, or to ever have had HIV testing (67.8% v. 44.6%). STI testing in the past 12 months was reported by 38.7% of sexually active MSM. Conclusion: Our findings show no significant differences in access to healthcare between MSM and non-MSM. MSM were more likely to receive HIV- and STI-related preventive services than non-MSM. However, the low STI testing rate among MSM highlights the need for interventions to increase STI testing, and HIV and STI counselling for MSM. Adapted from the source document. JF - Sexual Health AU - Tao, Guoyu AU - Hoover, Karen W AD - Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road NE, MS-E80, Atlanta, GA 30333, USA Y1 - 2013/09// PY - 2013 DA - September 2013 SP - 363 EP - 368 PB - CSIRO Publishing, Collingwood Australia VL - 10 IS - 4 SN - 1448-5028, 1448-5028 KW - Sexual behaviour KW - Health care KW - Men KW - HIV KW - Sexually transmitted diseases KW - Homosexuals KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1463071819?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Sexual+Health&rft.atitle=Differences+in+access+to+healthcare+and+utilisation+of+HIV+and+sexually+transmissible+infection+services+between+men+who+have+sex+with+men+and+men+who+have+sex+only+with+women%3A+results+of+the+2006-10+National+Survey+of+Family+Growth+in+the+United+States&rft.au=Tao%2C+Guoyu%3BHoover%2C+Karen+W&rft.aulast=Tao&rft.aufirst=Guoyu&rft.date=2013-09-01&rft.volume=10&rft.issue=4&rft.spage=363&rft.isbn=&rft.btitle=&rft.title=Sexual+Health&rft.issn=14485028&rft_id=info:doi/10.1071%2FSH13017 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2013-12-01 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Homosexuals; Sexually transmitted diseases; Health care; HIV; Men; Sexual behaviour DO - http://dx.doi.org/10.1071/SH13017 ER - TY - JOUR T1 - A Literature Review of Laboratory-Acquired Brucellosis AN - 1439224701; 18450165 AB - Brucellosis is a bacterial zoonotic disease which has been associated with laboratory-acquired infections. No recent reviews have addressed the characteristics of laboratory-acquired brucellosis (LAB). English-language literature was reviewed to identify reports of laboratory exposures to Brucella spp. and LAB cases between 1982 and 2007. Evaluation of 28 case reports identified 167 potentially exposed laboratory workers, of whom 71 had LAB. Nine reports were identified that summarized an additional 186 cases of LAB. Only 18 (11%) exposures were due to laboratory accidents, 147 (88%) exposures were due to aerosolization of organisms during routine identification activities, and the circumstances of 2 (1%) exposures were unknown. Brucella melitensis was the causative agent in 80% (135/167) of the exposures. Workers with high-risk exposures were 9.3 times more likely to develop LAB than workers with low-risk exposures (95% confidence interval [CI], 3.0 to 38.6; P < 0.0001); they were also 0.009 times likelier to develop LAB if they took antimicrobial PEP than if they did not (95% CI, 0 to 0.042; P < 0.0001). The median incubation period in case and summary reports was 8 weeks (range 1 to 40 weeks). Antimicrobial PEP is effective in preventing LAB. The incubation period may be used to identify appropriate serological and symptom surveillance time frames for exposed laboratory workers. JF - Journal of Clinical Microbiology AU - Traxler, Rita M AU - Lehman, Mark W AU - Bosserman, Elizabeth A AU - Guerra, Marta A AU - Smith, Theresa L Y1 - 2013/09// PY - 2013 DA - September 2013 SP - 3055 EP - 3062 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 51 IS - 9 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Workers KW - Accidents KW - Literature reviews KW - Case reports KW - Brucella melitensis KW - Reviews KW - Risk groups KW - Brucellosis KW - Infection KW - Occupational exposure KW - Antimicrobial agents KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1439224701?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=A+Literature+Review+of+Laboratory-Acquired+Brucellosis&rft.au=Traxler%2C+Rita+M%3BLehman%2C+Mark+W%3BBosserman%2C+Elizabeth+A%3BGuerra%2C+Marta+A%3BSmith%2C+Theresa+L&rft.aulast=Traxler&rft.aufirst=Rita&rft.date=2013-09-01&rft.volume=51&rft.issue=9&rft.spage=3055&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.00135-13 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-10-01 N1 - Number of references - 77 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Workers; Accidents; Case reports; Literature reviews; Reviews; Risk groups; Infection; Brucellosis; Occupational exposure; Antimicrobial agents; Brucella melitensis DO - http://dx.doi.org/10.1128/JCM.00135-13 ER - TY - JOUR T1 - Review of Brucellosis Cases from Laboratory Exposures in the United States in 2008 to 2011 and Improved Strategies for Disease Prevention AN - 1439223891; 18450178 AB - Five laboratory-acquired brucellosis (LAB) cases that occurred in the United States between 2008 and 2011 are presented. The Centers for Disease Control and Prevention (CDC) reviewed the recommendations published in 2008 and the published literature to identify strategies to further prevent LAB. The improved prevention strategies are described. JF - Journal of Clinical Microbiology AU - Traxler, R M AU - Guerra, M A AU - Morrow, M G AU - Haupt, T AU - Morrison, J AU - Saah, J R AU - Smith, C G AU - Williams, C AU - Fleischauer, A T AU - Lee, P A Y1 - 2013/09// PY - 2013 DA - September 2013 SP - 3132 EP - 3136 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 51 IS - 9 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Reviews KW - Disease control KW - Brucellosis KW - J 02300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1439223891?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Review+of+Brucellosis+Cases+from+Laboratory+Exposures+in+the+United+States+in+2008+to+2011+and+Improved+Strategies+for+Disease+Prevention&rft.au=Traxler%2C+R+M%3BGuerra%2C+M+A%3BMorrow%2C+M+G%3BHaupt%2C+T%3BMorrison%2C+J%3BSaah%2C+J+R%3BSmith%2C+C+G%3BWilliams%2C+C%3BFleischauer%2C+A+T%3BLee%2C+P+A&rft.aulast=Traxler&rft.aufirst=R&rft.date=2013-09-01&rft.volume=51&rft.issue=9&rft.spage=3132&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.00813-13 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-10-01 N1 - Number of references - 32 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Reviews; Disease control; Brucellosis DO - http://dx.doi.org/10.1128/JCM.00813-13 ER - TY - JOUR T1 - School-Based Programs Aimed at the Prevention and Treatment of Obesity: Evidence-Based Interventions for Youth in Latin America AN - 1430187900; 201318606 AB - Rapidly rising childhood obesity rates constitute a public health priority in Latin America which makes it imperative to develop evidence-based strategies. Schools are a promising setting but to date it is unclear how many school-based obesity interventions have been documented in Latin America and what level of evidence can be gathered from such interventions. We performed a systematic review of papers published between 1965 and December 2010. Interventions were considered eligible if they had a school-based component, were done in Latin America, evaluated an obesity related outcome (body mass index [BMI], weight, %body fat, waist circumference, BMIz-score), and compared youth exposed vs not exposed. Ten studies were identified as having a school-based component. Most interventions had a sample of normal and overweight children. The most successful interventions focused on prevention rather than treatment, had longer follow-ups, a multidisciplinary team, and fewer limitations in execution. Three prevention and 2 treatment interventions found sufficient improvements in obesity-related outcomes. We found sufficient evidence to recommend school-based interventions to prevent obesity among youth in Latin America. Evidence-based interventions in the school setting should be promoted as an important component for integrated programs, policies, and monitoring frameworks designed to reverse the childhood obesity in the region. Adapted from the source document. JF - Journal of School Health AU - Lobelo, Felipe AU - Garcia de Quevedo, Isabel AU - Holub, Christina K AU - Nagle, Brian J AU - Arredondo, Elva M AU - Barquera, Simon AU - Elder, John P AD - Global Health Promotion Office, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, NE, MS K-40 Atlanta, GA 30341 rlobelo@cdc.gov Y1 - 2013/09// PY - 2013 DA - September 2013 SP - 668 EP - 677 PB - Wiley-Blackwell, UK VL - 83 IS - 9 SN - 0022-4391, 0022-4391 KW - Obesity KW - Prevention KW - Interventions KW - Latin America KW - School based KW - Obese children KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1430187900?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+School+Health&rft.atitle=School-Based+Programs+Aimed+at+the+Prevention+and+Treatment+of+Obesity%3A+Evidence-Based+Interventions+for+Youth+in+Latin+America&rft.au=Lobelo%2C+Felipe%3BGarcia+de+Quevedo%2C+Isabel%3BHolub%2C+Christina+K%3BNagle%2C+Brian+J%3BArredondo%2C+Elva+M%3BBarquera%2C+Simon%3BElder%2C+John+P&rft.aulast=Lobelo&rft.aufirst=Felipe&rft.date=2013-09-01&rft.volume=83&rft.issue=9&rft.spage=668&rft.isbn=&rft.btitle=&rft.title=Journal+of+School+Health&rft.issn=00224391&rft_id=info:doi/10.1111%2Fjosh.12080 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2013-09-01 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Interventions; Obesity; School based; Latin America; Obese children; Prevention DO - http://dx.doi.org/10.1111/josh.12080 ER - TY - JOUR T1 - Updated US Public Health Service guidelines for the management of occupational exposures to human immunodeficiency virus and recommendations for postexposure prophylaxis. AN - 1418366784; 23917901 AB - This report updates US Public Health Service recommendations for the management of healthcare personnel (HCP) who experience occupational exposure to blood and/or other body fluids that might contain human immunodeficiency virus (HIV). Although the principles of exposure management remain unchanged, recommended HIV postexposure prophylaxis (PEP) regimens and the duration of HIV follow-up testing for exposed personnel have been updated. This report emphasizes the importance of primary prevention strategies, the prompt reporting and management of occupational exposures, adherence to recommended HIV PEP regimens when indicated for an exposure, expert consultation in management of exposures, follow-up of exposed HCP to improve adherence to PEP, and careful monitoring for adverse events related to treatment, as well as for virologic, immunologic, and serologic signs of infection. To ensure timely postexposure management and administration of HIV PEP, clinicians should consider occupational exposures as urgent medical concerns, and institutions should take steps to ensure that staff are aware of both the importance of and the institutional mechanisms available for reporting and seeking care for such exposures. The following is a summary of recommendations: (1) PEP is recommended when occupational exposures to HIV occur; (2) the HIV status of the exposure source patient should be determined, if possible, to guide need for HIV PEP; (3) PEP medication regimens should be started as soon as possible after occupational exposure to HIV, and they should be continued for a 4-week duration; (4) new recommendation-PEP medication regimens should contain 3 (or more) antiretroviral drugs (listed in Appendix A ) for all occupational exposures to HIV; (5) expert consultation is recommended for any occupational exposures to HIV and at a minimum for situations described in Box 1 ; (6) close follow-up for exposed personnel ( Box 2 ) should be provided that includes counseling, baseline and follow-up HIV testing, and monitoring for drug toxicity; follow-up appointments should begin within 72 hours of an HIV exposure; and (7) new recommendation-if a newer fourth-generation combination HIV p24 antigen-HIV antibody test is utilized for follow-up HIV testing of exposed HCP, HIV testing may be concluded 4 months after exposure ( Box 2 ); if a newer testing platform is not available, follow-up HIV testing is typically concluded 6 months after an HIV exposure. JF - Infection control and hospital epidemiology AU - Kuhar, David T AU - Henderson, David K AU - Struble, Kimberly A AU - Heneine, Walid AU - Thomas, Vasavi AU - Cheever, Laura W AU - Gomaa, Ahmed AU - Panlilio, Adelisa L AU - US Public Health Service Working Group AD - Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. jto7@cdc.gov ; US Public Health Service Working Group Y1 - 2013/09// PY - 2013 DA - September 2013 SP - 875 EP - 892 VL - 34 IS - 9 KW - Anti-HIV Agents KW - 0 KW - Index Medicus KW - Nursing KW - Anti-HIV Agents -- therapeutic use KW - Risk Factors KW - Humans KW - Occupational Diseases -- prevention & control KW - Emergency Medicine -- standards KW - Anti-HIV Agents -- adverse effects KW - Anti-HIV Agents -- administration & dosage KW - Female KW - Pregnancy KW - Occupational Exposure -- prevention & control KW - HIV Infections -- transmission KW - HIV Infections -- prevention & control KW - Health Personnel -- standards KW - Post-Exposure Prophylaxis -- standards UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1418366784?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Infection+control+and+hospital+epidemiology&rft.atitle=Updated+US+Public+Health+Service+guidelines+for+the+management+of+occupational+exposures+to+human+immunodeficiency+virus+and+recommendations+for+postexposure+prophylaxis.&rft.au=Kuhar%2C+David+T%3BHenderson%2C+David+K%3BStruble%2C+Kimberly+A%3BHeneine%2C+Walid%3BThomas%2C+Vasavi%3BCheever%2C+Laura+W%3BGomaa%2C+Ahmed%3BPanlilio%2C+Adelisa+L%3BUS+Public+Health+Service+Working+Group&rft.aulast=Kuhar&rft.aufirst=David&rft.date=2013-09-01&rft.volume=34&rft.issue=9&rft.spage=875&rft.isbn=&rft.btitle=&rft.title=Infection+control+and+hospital+epidemiology&rft.issn=1559-6834&rft_id=info:doi/10.1086%2F672271 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2014-03-20 N1 - Date created - 2013-08-06 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Comment In: Infect Control Hosp Epidemiol. 2014 Mar;35(3):328-9 [24521605] Infect Control Hosp Epidemiol. 2014 Mar;35(3):326-8 [24521604] Erratum In: Infect Control Hosp Epidemiol. 2013 Nov;34(11):1238 N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.1086/672271 ER - TY - JOUR T1 - Viral Hepatitis C Gets Personal - The Value of Human Genomics to Public Health AN - 1773905032; PQ0002707867 AB - About 180 million people worldwide are chronically infected with hepatitis C virus (HCV), with 3-4 million newly infected each year. Only 15-25% of acute HCV infections clear spontaneously, and the remainder persists as chronic HCV infection. More than 350,000 people die every year from hepatitis C-related liver failure and cancer. There is currently no vaccine and the standard-of-care therapies - peg-interferon alpha (pegIFN) plus ribavirin (RBV) - are expensive and have serious side effects. Also, they may be effective in only 40-50% of patients infected with HCV genotype 1, the most common HCV genotype in the US. Interleukin 28B (IL28B) genotype was recently and convincingly associated with response to pegIFN and RBV therapy. It has emerged as a robust pretreatment predictor of sustained virological response (SVR, i.e. virologic clearance) to pegIFN and RBV as well as to new triple therapy regimens that include a direct-acting antiviral agent with pegIFN and RBV and increase SVR rates as much as 75% in patients infected with HCV genotype 1. Testing for IL28B genotype may contribute to clinical decision-making and could inform clinical guidelines and public health policies. copyright 2013 S. Karger AG, Basel JF - Public Health Genomics AU - Zhang, L AU - Gwinn, M AU - Hu, D J AD - Division of Viral Hepatitis, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention Y1 - 2013/08// PY - 2013 DA - August 2013 SP - 192 EP - 197 PB - S. Karger AG, P.O. Box Basel CH-4009 Switzerland VL - 16 IS - 4 SN - 1662-4246, 1662-4246 KW - Virology & AIDS Abstracts; Genetics Abstracts; Health & Safety Science Abstracts KW - Hepatitis C KW - Host genetic predisposition to disease KW - IL28B polymorphism KW - Interferon response KW - Liver cancer KW - Ribavirin KW - Genotypes KW - Infection KW - Public health KW - Antiviral agents KW - genomics KW - Liver diseases KW - Guidelines KW - Cancer KW - Hepatitis KW - Decision making KW - Hepatitis C virus KW - Chronic infection KW - Liver KW - Vaccines KW - Side effects KW - G 07880:Human Genetics KW - V 22400:Human Diseases KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1773905032?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Public+Health+Genomics&rft.atitle=Viral+Hepatitis+C+Gets+Personal+-+The+Value+of+Human+Genomics+to+Public+Health&rft.au=Zhang%2C+L%3BGwinn%2C+M%3BHu%2C+D+J&rft.aulast=Zhang&rft.aufirst=L&rft.date=2013-08-01&rft.volume=16&rft.issue=4&rft.spage=192&rft.isbn=&rft.btitle=&rft.title=Public+Health+Genomics&rft.issn=16624246&rft_id=info:doi/10.1159%2F000352014 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-03-01 N1 - Last updated - 2016-09-14 N1 - SubjectsTermNotLitGenreText - Liver diseases; Liver cancer; Ribavirin; Genotypes; Cancer; Public health; Decision making; Antiviral agents; Chronic infection; genomics; Hepatitis C; Vaccines; Side effects; Hepatitis; Guidelines; Liver; Infection; Hepatitis C virus DO - http://dx.doi.org/10.1159/000352014 ER - TY - JOUR T1 - Outpatient colonoscopy complications in the CDC's Colorectal Cancer Screening Demonstration Program AN - 1434015805; 18487001 AB - BACKGROUND To the authors's knowledge, there are few published prospective cohort studies of colonoscopy complications in patients at average risk for colorectal cancer who received colorectal cancer screening from a community-based program. In this article, the authors report the rate of colonoscopy complications in the Centers for Disease Control and Prevention (CDC)'s Colorectal Cancer Screening Demonstration Program (CRCSDP), which provided colorectal cancer screening to a medically underserved population aged 50 years to 64 years for screening, diagnostic follow-up after positive stool blood tests, and surveillance purposes. METHODS Clinical data were collected prospectively from 5 community-based colorectal cancer screening programs. Complications were identified by reviewing the standardized clinical data and medical complication reporting forms submitted by the programs to the CDC. Serious complications were defined as conditions or symptoms that resulted in hospital admission within 30 days after the procedure, including perforation, gastrointestinal bleeding requiring or not requiring blood transfusion, cardiopulmonary events, postpolypectomy syndrome, excessive abdominal pain, or death. RESULTS A total of 3215 individuals underwent 3355 colonoscopies. Of these, 89% of the colonoscopies were conducted for screening, 9% were conducted for diagnostic follow-up, and 2% were conducted for surveillance purposes. The mean age of the individuals was 55.9 years. Eight individuals experienced serious complications, for an incidence of 2.38 per 1000 colonoscopies. Three patients experienced bowel perforations that required surgery, 1 patient was hospitalized for postpolypectomy bleeding, 3 patients experienced cardiopulmonary events, and 1 patient visited the emergency room for excessive abdominal pain and underwent surgery for an identified colorectal mass. No deaths were reported. CONCLUSIONS In the CDC's CRCSDP, in which a total of 3215 individuals underwent 3355 colonoscopies, the overall incidence of serious complications from colonoscopy was found to be low. Cancer 2013; 119(15 suppl):2849-54. [copy 2013 American Cancer Society. This article reports the rate of complications from colonoscopy in the Centers for Disease Control and Prevention's Colorectal Cancer Screening Demonstration Program. The overall incidence of serious complications from colonoscopy was 2.38 per 1000 procedures. JF - Cancer AU - Castro, Georgina AU - Azrak, MFuad AU - Seeff, Laura C AU - Royalty, Janet AD - Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia. Y1 - 2013/08// PY - 2013 DA - Aug 2013 SP - 2849 EP - 2854 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 119 SN - 0008-543X, 0008-543X KW - Risk Abstracts KW - Mortality KW - Prevention KW - Complications KW - Surgery KW - Community involvement KW - Disease control KW - Colorectal carcinoma KW - Pain KW - Hospitals KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1434015805?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cancer&rft.atitle=Outpatient+colonoscopy+complications+in+the+CDC%27s+Colorectal+Cancer+Screening+Demonstration+Program&rft.au=Castro%2C+Georgina%3BAzrak%2C+MFuad%3BSeeff%2C+Laura+C%3BRoyalty%2C+Janet&rft.aulast=Castro&rft.aufirst=Georgina&rft.date=2013-08-01&rft.volume=119&rft.issue=&rft.spage=2849&rft.isbn=&rft.btitle=&rft.title=Cancer&rft.issn=0008543X&rft_id=info:doi/10.1002%2Fcncr.28159 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-09-01 N1 - Last updated - 2013-10-04 N1 - SubjectsTermNotLitGenreText - Mortality; Prevention; Complications; Community involvement; Surgery; Disease control; Colorectal carcinoma; Pain; Hospitals DO - http://dx.doi.org/10.1002/cncr.28159 ER - TY - JOUR T1 - Sexual Violence Perpetration by Adolescents in Dating versus Same-Sex Peer Relationships: Differences in Associated Risk and Protective Factors AN - 1434014756; 18436659 AB - Introduction: Little is known about the risk and protective factors for youth sexual violence (SV) perpetration across different types of relationships. This study examined factors associated with perpetrating SV against a dating partner and a same-sex peer. Methods: Analyses were based on data from a survey conducted in 2004 with public school boys and girls in grades 7, 9, 11, and 12 (N = 4,131) in a high-risk, urban school district in the United States. SV perpetration was defined broadly to include forcing someone, about the same age and of the same or opposite sex as the respondent, to have sex or to do something sexual that they did not want to do. Analyses examined the associations between risk and protective factors and SV perpetration, adjusting for SV victimization and demographic characteristics. Results: Findings revealed that 2.1% of respondents reported perpetration against a same-sex peer and 3.2% reported perpetration against a date during the past 12 months. Victims of SV for each relationship type were more likely than non-victims to perpetrate SV. A combination of factors across the individual, relationship, and community level were significantly associated with SV perpetration and there were both shared and unique factors across the relationship types. Conclusion: Data suggest that programs to prevent SV perpetration for both relationship types should start when students are young, with particular focus on middle school boys. Prevention efforts should have slightly different foci to address these 2 types of SV perpetration. JF - Western Journal of Emergency Medicine AU - Basile, Kathleen C AU - Hamburger, Merle E AU - Swahn, Monica H AU - Choi, Colleen AD - Centers for Disease Control and Prevention, National Center for Injury Prevention and Control, Division of Violence Prevention, Atlanta, Georgia Y1 - 2013/08// PY - 2013 DA - Aug 2013 SP - 329 EP - 340 PB - California Digital Library, University of California Oakland CA 94612-2901 United States VL - 14 IS - 4 SN - 1936-900X, 1936-900X KW - Risk Abstracts; Health & Safety Science Abstracts KW - Demography KW - USA KW - Age KW - Prevention KW - Schools KW - Risk factors KW - Sexual assault KW - Adolescents KW - Victimization KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1434014756?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Western+Journal+of+Emergency+Medicine&rft.atitle=Sexual+Violence+Perpetration+by+Adolescents+in+Dating+versus+Same-Sex+Peer+Relationships%3A+Differences+in+Associated+Risk+and+Protective+Factors&rft.au=Basile%2C+Kathleen+C%3BHamburger%2C+Merle+E%3BSwahn%2C+Monica+H%3BChoi%2C+Colleen&rft.aulast=Basile&rft.aufirst=Kathleen&rft.date=2013-08-01&rft.volume=14&rft.issue=4&rft.spage=329&rft.isbn=&rft.btitle=&rft.title=Western+Journal+of+Emergency+Medicine&rft.issn=1936900X&rft_id=info:doi/10.5811%2Fwestjem.2013.3.15684 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-09-01 N1 - Last updated - 2013-10-04 N1 - SubjectsTermNotLitGenreText - Demography; Prevention; Age; Schools; Risk factors; Sexual assault; Victimization; Adolescents; USA DO - http://dx.doi.org/10.5811/westjem.2013.3.15684 ER - TY - JOUR T1 - Implementing the CDC's Colorectal Cancer Screening Demonstration Program: Wisdom from the field AN - 1434013692; 18487012 AB - BACKGROUND Colorectal cancer, as the second leading cause of cancer-related deaths among men and women in the United States, represents an important area for public health intervention. Although colorectal cancer screening can prevent cancer and detect disease early when treatment is most effective, few organized public health screening programs have been implemented and evaluated. From 2005 to 2009, the Centers for Disease Control and Prevention funded 5 sites to participate in the Colorectal Cancer Screening Demonstration Program (CRCSDP), which was designed to reach medically underserved populations. METHODS The authors conducted a longitudinal, multiple case study to analyze program implementation processes. Qualitative methods included interviews with 100 stakeholders, 125 observations, and review of 19 documents. Data were analyzed within and across cases. RESULTS Several themes related to CRCSDP implementation emerged from the cross-case analysis: the complexity of colorectal cancer screening, the need for teamwork and collaboration, integration of the program into existing systems, the ability of programs to use wisdom at the local level, and the influence of social norms. Although these themes were explored independently from 1 another, interaction across themes was evident. CONCLUSIONS Colorectal cancer screening is clinically complex, and its screening methods are not well accepted by the general public; both of these circumstances have implications for program implementation. Using patient navigation, engaging in transdisciplinary teamwork, assimilating new programs into existing clinical settings, and deferring to local-level wisdom together helped to address complexity and enhance program implementation. In addition, public health efforts must confront negative social norms around colorectal cancer screening. Cancer 2013; 119(15 suppl):2870-83. [copy 2013 American Cancer Society. Findings from this qualitative, multiple case study evaluation of program implementation processes highlight the following themes: the complexity of colorectal cancer screening, teamwork and collaboration, integration of the program into existing systems, the ability of programs to use wisdom at the local level, and the influence of social norms. Implications include using patient navigation, engaging in transdisciplinary teamwork, assimilating new programs into existing clinical settings, and deferring to local-level wisdom to help address complexity and enhance program implementation; public health efforts must confront negative social norms around colorectal cancer screening. JF - Cancer AU - Rohan, Elizabeth A AU - Boehm, Jennifer E AU - DeGroff, Amy AU - Glover-Kudon, Rebecca AU - Preissle, Judith AD - Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia. Y1 - 2013/08// PY - 2013 DA - Aug 2013 SP - 2870 EP - 2883 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 119 SN - 0008-543X, 0008-543X KW - Health & Safety Science Abstracts KW - Case studies KW - USA KW - Colorectal carcinoma KW - H 2000:Transportation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1434013692?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cancer&rft.atitle=Implementing+the+CDC%27s+Colorectal+Cancer+Screening+Demonstration+Program%3A+Wisdom+from+the+field&rft.au=Rohan%2C+Elizabeth+A%3BBoehm%2C+Jennifer+E%3BDeGroff%2C+Amy%3BGlover-Kudon%2C+Rebecca%3BPreissle%2C+Judith&rft.aulast=Rohan&rft.aufirst=Elizabeth&rft.date=2013-08-01&rft.volume=119&rft.issue=&rft.spage=2870&rft.isbn=&rft.btitle=&rft.title=Cancer&rft.issn=0008543X&rft_id=info:doi/10.1002%2Fcncr.28162 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-09-01 N1 - Last updated - 2014-03-10 N1 - SubjectsTermNotLitGenreText - Colorectal carcinoma; USA DO - http://dx.doi.org/10.1002/cncr.28162 ER - TY - JOUR T1 - Time-Lapse Analysis of Methane Quantity in the Mary Lee Group of Coal Seams Using Filter-Based Multiple-Point Geostatistical Simulation AN - 1427005128; 18326009 AB - Coal seam degasification and its success are important for controlling methane, and thus for the health and safety of coal miners. During the course of degasification, properties of coal seams change. Thus, the changes in coal reservoir conditions and in-place gas content as well as methane emission potential into mines should be evaluated by examining time-dependent changes and the presence of major heterogeneities and geological discontinuities in the field. In this work, time-lapsed reservoir and fluid storage properties of the New Castle coal seam, Mary Lee/Blue Creek seam, and Jagger seam of Black Warrior Basin, Alabama, were determined from gas and water production history matching and production forecasting of vertical degasification wellbores. These properties were combined with isotherm and other important data to compute gas-in-place (GIP) and its change with time at borehole locations. Time-lapsed training images (TIs) of GIP and GIP difference corresponding to each coal and date were generated by using these point-wise data and Voronoi decomposition on the TI grid, which included faults as discontinuities for expansion of Voronoi regions. Filter-based multiple-point geostatistical simulations, which were preferred in this study due to anisotropies and discontinuities in the area, were used to predict time-lapsed GIP distributions within the study area. Performed simulations were used for mapping spatial time-lapsed methane quantities as well as their uncertainties within the study area. The systematic approach presented in this paper is the first time in literature that history matching, TIs of GIPs and filter simulations are used for degasification performance evaluation and for assessing GIP for mining safety. Results from this study showed that using production history matching of coalbed methane wells to determine time-lapsed reservoir data could be used to compute spatial GIP and representative GIP TIs generated through Voronoi decomposition. Furthermore, performing filter simulations using point-wise data and TIs could be used to predict methane quantity in coal seams subjected to degasification. During the course of the study, it was shown that the material balance of gas produced by wellbores and the GIP reductions in coal seams predicted using filter simulations compared very well, showing the success of filter simulations for continuous variables in this case study. Quantitative results from filter simulations of GIP within the studied area briefly showed that GIP was reduced from an initial 73 Bcf (median) to 46 Bcf (2011), representing a 37 % decrease and varying spatially through degasification. It is forecasted that there will be an additional 2 Bcf reduction in methane quantity between 2011 and 2015. This study and presented results showed that the applied methodology and utilized techniques can be used to map GIP and its change within coal seams after degasification, which can further be used for ventilation design for methane control in coal mines. JF - Mathematical Geosciences AU - Oezgen Karacan, C AU - Olea, Ricardo A AD - NIOSH, Office of Mine Safety and Health Research, Pittsburgh, PA, 15236, USA, cok6@cdc.gov Y1 - 2013/08// PY - 2013 DA - Aug 2013 SP - 681 EP - 704 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 45 IS - 6 SN - 1874-8961, 1874-8961 KW - Water Resources Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Meteorological & Geoastrophysical Abstracts KW - Prediction KW - Methane KW - Reservoir KW - Anisotropy KW - Degradation KW - Safety KW - Simulation KW - Coal KW - Creek KW - Decomposition KW - Boreholes KW - Filters KW - USA, Alabama KW - Numerical simulations KW - History KW - Methane emission KW - Health and safety KW - Isotherms KW - Heterogeneity KW - Reservoirs KW - M2 556.55:Lakes, Reservoirs, Ponds (556.55) KW - Q2 09270:Seismology KW - SW 5080:Evaluation, processing and publication UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1427005128?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Mathematical+Geosciences&rft.atitle=Time-Lapse+Analysis+of+Methane+Quantity+in+the+Mary+Lee+Group+of+Coal+Seams+Using+Filter-Based+Multiple-Point+Geostatistical+Simulation&rft.au=Oezgen+Karacan%2C+C%3BOlea%2C+Ricardo+A&rft.aulast=Oezgen+Karacan&rft.aufirst=C&rft.date=2013-08-01&rft.volume=45&rft.issue=6&rft.spage=681&rft.isbn=&rft.btitle=&rft.title=Mathematical+Geosciences&rft.issn=18748961&rft_id=info:doi/10.1007%2Fs11004-013-9474-1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-01 N1 - Number of references - 38 N1 - Last updated - 2015-03-20 N1 - SubjectsTermNotLitGenreText - Prediction; Reservoir; Methane; Degradation; Health and safety; Simulation; Coal; Creek; Isotherms; Anisotropy; Numerical simulations; Methane emission; Reservoirs; Filters; History; Safety; Heterogeneity; Boreholes; Decomposition; USA, Alabama DO - http://dx.doi.org/10.1007/s11004-013-9474-1 ER - TY - JOUR T1 - Interpersonal- and Community-Level Predictors of Intimate Partner Violence Perpetration among African American Men AN - 1427001903; 18325982 AB - Intimate partner violence (IPV) has been associated with adverse physical, psychoemotional, and sexual health, and African American women are at higher risk for experiencing IPV. Considering African American women predominantly have African American male partners, it is essential to identify factors associated with IPV perpetration among African American men. The present study examined attitudes toward IPV, ineffective couple conflict resolution, exposure to neighborhood violence, and the interplay of these factors as predictors of IPV perpetration. A community sample of 80 single, heterosexual, African American men between 18 and 29 years completed measures assessing sociodemographics, attitudes towards IPV, perceived ineffective couple conflict resolution, exposure to neighborhood violence, and IPV perpetration during the past 3 months. Hierarchical multiple linear regression analyses, with age, education, and public assistance as covariates, were conducted on 65 men who reported being in a main relationship. Couple conflict resolution and exposure to neighborhood violence moderated the relation between attitudes supporting IPV and IPV perpetration. Among men who reported high ineffective couple conflict resolution and high exposure to neighborhood violence, IPV perpetration increased as attitudes supporting IPV increased. The findings indicated that interpersonal- and community-level factors interact with individual level factors to increase the risk of recent IPV perpetration among African American men. While IPV prevention should include individual-level interventions that focus on skills building, these findings also highlight the importance of couple-, community-, and structural-level interventions. JF - Journal of Urban Health AU - Raiford, Jerris Laverne AU - Seth, Puja AU - Braxton, Nikia D AU - DiClemente, Ralph J AD - Centers for Disease Control and Prevention, Atlanta, GA, USA, jraiford@cdc.gov Y1 - 2013/08// PY - 2013 DA - Aug 2013 SP - 784 EP - 795 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 90 IS - 4 SN - 1099-3460, 1099-3460 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Attitudes KW - Education KW - Perception KW - Males KW - Intervention KW - Domestic violence KW - Conflicts KW - Violence KW - Ethnic groups KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1427001903?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Urban+Health&rft.atitle=Interpersonal-+and+Community-Level+Predictors+of+Intimate+Partner+Violence+Perpetration+among+African+American+Men&rft.au=Raiford%2C+Jerris+Laverne%3BSeth%2C+Puja%3BBraxton%2C+Nikia+D%3BDiClemente%2C+Ralph+J&rft.aulast=Raiford&rft.aufirst=Jerris&rft.date=2013-08-01&rft.volume=90&rft.issue=4&rft.spage=784&rft.isbn=&rft.btitle=&rft.title=Journal+of+Urban+Health&rft.issn=10993460&rft_id=info:doi/10.1007%2Fs11524-012-9717-3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-01 N1 - Number of references - 57 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Education; Attitudes; Perception; Males; Intervention; Domestic violence; Conflicts; Violence; Ethnic groups DO - http://dx.doi.org/10.1007/s11524-012-9717-3 ER - TY - JOUR T1 - N-Linked Glycosylation of the Hemagglutinin Protein Influences Virulence and Antigenicity of the 1918 Pandemic and Seasonal H1N1 Influenza A Viruses AN - 1419372200; 18266713 AB - The hemagglutinin (HA) protein is a major virulence determinant for the 1918 pandemic influenza virus; however, it encodes no known virulence-associated determinants. In comparison to seasonal influenza viruses of lesser virulence, the 1918 H1N1 virus has fewer glycosylation sequons on the HA globular head region. Using site-directed mutagenesis, we found that a 1918 HA recombinant virus, of high virulence, could be significantly attenuated in mice by adding two additional glycosylation sites (asparagine [Asn] 71 and Asn 286) on the side of the HA head. The 1918 HA recombinant virus was further attenuated by introducing two additional glycosylation sites on the top of the HA head at Asn 142 and Asn 172. In a reciprocal experimental approach, deletion of HA glycosylation sites (Asn 142 and Asn 177, but not Asn 71 and Asn 104) from a seasonal influenza H1N1 virus, A/Solomon Islands/2006 (SI/06), led to increased virulence in mice. The addition of glycosylation sites to 1918 HA and removal of glycosylation sites from SI/06 HA imposed constraints on the theoretical structure surrounding the glycan receptor binding sites, which in turn led to distinct glycan receptor binding properties. The modification of glycosylation sites for the 1918 and SI/06 viruses also caused changes in viral antigenicity based on cross-reactive hemagglutinin inhibition antibody titers with antisera from mice infected with wild-type or glycan mutant viruses. These results demonstrate that glycosylation patterns of the 1918 and seasonal H1N1 viruses directly contribute to differences in virulence and are partially responsible for their distinct antigenicity. JF - Journal of Virology AU - Sun, Xiangjie AU - Jayaraman, Akila AU - Maniprasad, Pavithra AU - Raman, Rahul AU - Houser, Katherine V AU - Pappas, Claudia AU - Zeng, Hui AU - Sasisekharan, Ram AU - Katz, Jacqueline M AU - Tumpey, Terrence M Y1 - 2013/08// PY - 2013 DA - Aug 2013 SP - 8756 EP - 8766 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 87 IS - 15 SN - 0022-538X, 0022-538X KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Receptor mechanisms KW - Antigenicity KW - Influenza A KW - Hemagglutinins KW - Viruses KW - Glycosylation KW - Polysaccharides KW - Asparagine KW - Mutants KW - Influenza KW - Virulence KW - pandemics KW - Sulfur dioxide KW - Islands KW - Seasonal variations KW - Site-directed mutagenesis KW - Head KW - Mice KW - ISE, Pacific, Solomon Is. KW - Antibodies KW - Antisera KW - Influenza virus KW - Proteins KW - V 22410:Animal Diseases KW - H 14000:Toxicology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1419372200?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Virology&rft.atitle=N-Linked+Glycosylation+of+the+Hemagglutinin+Protein+Influences+Virulence+and+Antigenicity+of+the+1918+Pandemic+and+Seasonal+H1N1+Influenza+A+Viruses&rft.au=Sun%2C+Xiangjie%3BJayaraman%2C+Akila%3BManiprasad%2C+Pavithra%3BRaman%2C+Rahul%3BHouser%2C+Katherine+V%3BPappas%2C+Claudia%3BZeng%2C+Hui%3BSasisekharan%2C+Ram%3BKatz%2C+Jacqueline+M%3BTumpey%2C+Terrence+M&rft.aulast=Sun&rft.aufirst=Xiangjie&rft.date=2013-08-01&rft.volume=87&rft.issue=15&rft.spage=8756&rft.isbn=&rft.btitle=&rft.title=Journal+of+Virology&rft.issn=0022538X&rft_id=info:doi/10.1128%2FJVI.00593-13 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-01 N1 - Number of references - 44 N1 - Last updated - 2014-08-07 N1 - SubjectsTermNotLitGenreText - Site-directed mutagenesis; Head; Receptor mechanisms; Antigenicity; Hemagglutinins; Influenza A; Glycosylation; Polysaccharides; Asparagine; Virulence; pandemics; Antisera; Antibodies; Islands; Influenza; Sulfur dioxide; Viruses; Proteins; Mice; Seasonal variations; Mutants; Influenza virus; ISE, Pacific, Solomon Is. DO - http://dx.doi.org/10.1128/JVI.00593-13 ER - TY - JOUR T1 - Syphilis-related perceptions not associated with risk behaviors among men who have sex with men having regular male sex partner(s) in Nanjing, China AN - 1417859515; 4469601 AB - The prevalence of HIV among men who sex with men (MSM)has been increasing sharply in China. The prevalence of unprotected anal intercourse (UAI)among them is very high, especially when male regular sex partners are involved. Many MSM having regular sex partners are engaged in multiple sex partnerships, which often involved UAI. This study interviewed 168 MSM in Nanjing, China, having had anal intercourse with at least one male regular sex partner in the last six months. Amongst the participants, 52.4% reported having had UAI with male regular sex partners whilst 50.0% reported multiple male sex partnerships in the last six months. Multivariate analysis showed that monthly personal income higher than 2000 RMB (multivariate OR = 0.49, 95% CI: 0.26-0.96), HIV antibody testing in the last year (multivariate OR = 0.19, 95% CI: 0.06-0.60), sexual position being both insertive and receptive during anal sex with male sex partners in general (multivariate OR = 0.43, 95% CI: 0.18-0.99; reference group: with receptive position only) were associated with lower likelihoods of UAI. Syphilis-related perceptions, including knowledge, cognitions (perceived susceptibility, perceived severity, self-efficacy in avoiding syphilis infection and perceived infectivity and perceived syphilis-related norms among MSM in general)were not associated with risk behaviors (UAI and multiple male sex partnerships). Our sampled MSM are exposed to very high risk of HIV/STD transmission. We found no association between syphilis-related perceptions and the two types of risk behaviors. Future studies are warranted to understand such associations in the context of sexual intercourse with nonregular sex partners among MSM. Reprinted by permission of Routledge, Taylor & Francis Ltd. JF - AIDS care AU - Wang, Zixin AU - Lau, Joseph T.F. AU - Hao, Chun AU - Yang, Haitao AU - Huan, Xiping AU - Yan, Hongjing AU - Guan, Wenhui AD - Chinese University of Hong Kong ; Virginia Commonwealth University ; Jiangsu Provincial Center for Disease Control and Prevention Y1 - 2013/08// PY - 2013 DA - Aug 2013 SP - 1010 EP - 1017 VL - 25 IS - 8 SN - 0954-0121, 0954-0121 KW - Sociology KW - Men who have sex with men (MSM) KW - Syphilis KW - Risk KW - Sexual behaviour KW - Perception KW - HIV KW - Sexual intercourse KW - China KW - Sexually transmitted diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1417859515?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+care&rft.atitle=Syphilis-related+perceptions+not+associated+with+risk+behaviors+among+men+who+have+sex+with+men+having+regular+male+sex+partner%28s%29+in+Nanjing%2C+China&rft.au=Wang%2C+Zixin%3BLau%2C+Joseph+T.F.%3BHao%2C+Chun%3BYang%2C+Haitao%3BHuan%2C+Xiping%3BYan%2C+Hongjing%3BGuan%2C+Wenhui&rft.aulast=Wang&rft.aufirst=Zixin&rft.date=2013-08-01&rft.volume=25&rft.issue=8&rft.spage=1010&rft.isbn=&rft.btitle=&rft.title=AIDS+care&rft.issn=09540121&rft_id=info:doi/10.1080%2F09540121.2012.748166 LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-08-05 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 11581 3617 6220; 11567 11563 1025 1542 11325 6071; 9382; 5703 3617 6220; 11035; 11563 1025 1542 11325 6071; 93 116 30 DO - http://dx.doi.org/10.1080/09540121.2012.748166 ER - TY - JOUR T1 - Antibiotic Resistance of Helicobacter Pylori Isolated in the Southeast Coastal Region of China AN - 1399922745; 18224160 AB - The resistance of Helicobacter pylori (H. pylori) to antibiotics is increasing worldwide, lowering its efficacy in current eradication therapies. This study evaluated H. pylori resistance to antibiotics in the southeast coastal region of China and suggests appropriate alternatives. Seventeen thousand seven hundred and thirty one H. pylori strains were collected from eight areas of two provinces in coastal southeast China from 2010 to 2012. The resistance of these strains to six antibiotics was tested using the agar dilution method. The resistance rates to clarithromycin, metronidazole, levofloxacin, amoxicillin, gentamicin and furazolidone were 21.5, 95.4, 20.6, 0.1, 0.1 and 0.1%, respectively. Double, triple and quadruple antibacterial resistant percentages were 25.5, 7.5 and 0.1%, respectively. A positive association between the resistance to levofloxacin and to clarithromycin was found, but there was a negative correlation in the resistances to levofloxacin and to metronidazole. The prevalence of H. pylori resistance to clarithromycin, metronidazole, levofloxacin and multiple antibiotics in coastal southeast China is high. Choice of therapy should be individualized based on a susceptibility test in this region of the country. JF - Helicobacter AU - Su, Peng AU - Li, Youming AU - Li, Hongzhang AU - Zhang, Jiakun AU - Lin, Lang AU - Wang, Qunying AU - Guo, Feng AU - Ji, Zizhong AU - Mao, Jibo AU - Tang, Wuheng AU - Shi, Zhengchao AU - Shao, Wei AU - Mao, Junliang AU - Zhu, Xinjian AU - Zhang, Xiaofeng AU - Tong, Yuefeng AU - Tu, Huimin AU - Jiang, Mizu AU - Wang, Zhiyong AU - Jin, Fengzhe AU - Yang, Ningmin AU - Zhang, Jianzhong AD - State Key Laboratory for Infectious Disease Prevention and Control National Institute for Communicable Disease Control and Prevention. Chinese Center for Disease Control and Prevention Y1 - 2013/08// PY - 2013 DA - Aug 2013 SP - 274 EP - 279 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 18 IS - 4 SN - 1083-4389, 1083-4389 KW - Microbiology Abstracts B: Bacteriology KW - Gentamicin KW - Helicobacter pylori KW - Metronidazole KW - Clarithromycin KW - Agar KW - Amoxicillin KW - Furazolidone KW - Levofloxacin KW - Antibiotics KW - Antibiotic resistance KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1399922745?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Helicobacter&rft.atitle=Antibiotic+Resistance+of+Helicobacter+Pylori+Isolated+in+the+Southeast+Coastal+Region+of+China&rft.au=Su%2C+Peng%3BLi%2C+Youming%3BLi%2C+Hongzhang%3BZhang%2C+Jiakun%3BLin%2C+Lang%3BWang%2C+Qunying%3BGuo%2C+Feng%3BJi%2C+Zizhong%3BMao%2C+Jibo%3BTang%2C+Wuheng%3BShi%2C+Zhengchao%3BShao%2C+Wei%3BMao%2C+Junliang%3BZhu%2C+Xinjian%3BZhang%2C+Xiaofeng%3BTong%2C+Yuefeng%3BTu%2C+Huimin%3BJiang%2C+Mizu%3BWang%2C+Zhiyong%3BJin%2C+Fengzhe%3BYang%2C+Ningmin%3BZhang%2C+Jianzhong&rft.aulast=Su&rft.aufirst=Peng&rft.date=2013-08-01&rft.volume=18&rft.issue=4&rft.spage=274&rft.isbn=&rft.btitle=&rft.title=Helicobacter&rft.issn=10834389&rft_id=info:doi/10.1111%2Fhel.12046 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-07-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Gentamicin; Agar; Clarithromycin; Metronidazole; Furazolidone; Amoxicillin; Levofloxacin; Antibiotics; Antibiotic resistance; Helicobacter pylori DO - http://dx.doi.org/10.1111/hel.12046 ER - TY - JOUR T1 - Critical issues in implementing a national integrated all-vaccine preventable disease surveillance system AN - 1443370929; 18663027 AB - In 2007, the World Health Organization published the Global Framework for Immunization Monitoring and Surveillance (GF1MS) outlining measures to enhance national surveillance for vaccine preventable diseases (VPDs). The GFIMS emphasized that VPD surveillance should be integrated and placed in a 'unified framework' building upon the strengths of existing surveillance systems to prevent duplication of activities common to all surveillance systems and to minimize human resource and supply expenditures. Unfortunately, there was little experience in actually developing integrated VPD surveillance. We describe the process of developing operational guidance for ministries of health to implement such an integrated surveillance system for multiple VPDs. JF - Vaccine AU - Hyde, T B AU - Andrus, J K AU - Dietz, V J AU - Lee, CE AU - Widdowson, M-A AU - Verani, J R AU - Friedman, C AU - Azziz-Baumgartner, E AU - Lopez, A S AU - Jumaan, A AD - Global Immunization Division, US Centers for Disease Control and Prevention (CDC), 1600 Clifton Road NE, Atlanta, GA 30333, USA, thyde@cdc.gov Y1 - 2013/07/02/ PY - 2013 DA - 2013 Jul 02 SP - C94 EP - C98 VL - 31 SN - 0264-410X, 0264-410X KW - Health & Safety Science Abstracts; Immunology Abstracts KW - Immunization KW - Vaccines KW - F:06905 KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1443370929?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Critical+issues+in+implementing+a+national+integrated+all-vaccine+preventable+disease+surveillance+system&rft.au=Hyde%2C+T+B%3BAndrus%2C+J+K%3BDietz%2C+V+J%3BLee%2C+CE%3BWiddowson%2C+M-A%3BVerani%2C+J+R%3BFriedman%2C+C%3BAzziz-Baumgartner%2C+E%3BLopez%2C+A+S%3BJumaan%2C+A&rft.aulast=Hyde&rft.aufirst=T&rft.date=2013-07-02&rft.volume=31&rft.issue=&rft.spage=C94&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-10-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Vaccines ER - TY - JOUR T1 - What do policy makers need to know? Lessons from the decision to add pneumococcal conjugate and rotavirus vaccines to the US immunization program AN - 1443369477; 18663014 AB - The decisions to introduce pneumococcal conjugate and rotavirus vaccines into the US immunization programs were good ones. The vaccines have performed even better than expected, markedly reducing disease not only among young children who received them but also among unvaccinated persons in the community [1,2]. But when the US Centers for Disease Control and Prevention (CDC) first considered whether to recommend routine use of these vaccines, several pieces of information - such as data on disease burden and vaccine efficacy, safety, and cost-effectiveness -had to be gathered before the decision to use these vaccines became clear. JF - Vaccine AU - Whitney, C G AU - Parashar, U D AD - National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, United States, cwhitney@cdc.gov Y1 - 2013/07/02/ PY - 2013 DA - 2013 Jul 02 SP - C6 EP - C7 VL - 31 SN - 0264-410X, 0264-410X KW - Virology & AIDS Abstracts; Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Children KW - Rotavirus KW - Vaccines KW - F 06905:Vaccines KW - J 02350:Immunology KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1443369477?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=What+do+policy+makers+need+to+know%3F+Lessons+from+the+decision+to+add+pneumococcal+conjugate+and+rotavirus+vaccines+to+the+US+immunization+program&rft.au=Whitney%2C+C+G%3BParashar%2C+U+D&rft.aulast=Whitney&rft.aufirst=C&rft.date=2013-07-02&rft.volume=31&rft.issue=&rft.spage=C6&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-10-01 N1 - Last updated - 2014-03-10 N1 - SubjectsTermNotLitGenreText - Vaccines; Rotavirus ER - TY - JOUR T1 - Unusual Enterocytozoon bieneusi Genotypes and Cryptosporidium hominis Subtypes in HIV-Infected Patients on Highly Active Antiretroviral Therapy AN - 1647004293; 21172153 AB - Human immunodeficiency virus (HIV)-infected persons are commonly infected with Cryptosporidium species and Enterocytozoon bieneusi in both developed and developing countries, particularly patients with CD4+ cell counts below 200 cells/ mu L; 285 HIV-infected patients on highly active antiretroviral therapy (HAART) were enrolled in this study, and both stool and blood specimens were collected from participants. The stool specimens were analyzed and typed for E. bieneusi and Cryptosporidium spp. by polymerase chain reaction (PCR) and DNA sequencing. CD4 count was analyzed using flow cytometry. E. bieneusi and Cryptosporidium were detected in 18 (6.3%) and 4 (1.4%) patients, respectively. The E. bieneusi detected mostly belonged to a new genotype group that, thus far, has only been found in a few humans: genotype Nig4 in 2 patients and two new genotypes related to Nig4 in 12 patients. The Cryptosporidium detected included C. hominis (two patients), C. parvum (one patient), and C. felis (one patient), with the two C. hominis infections belonging to an unusual subtype family. Additional studies are required to determine whether some E. bieneusi genotypes and C. hominis subtypes are more prevalent in HIV patients on HAART. JF - American Journal of Tropical Medicine and Hygiene AU - Akinbo, Frederick O AU - Okaka, Christopher E AU - Omoregie, Richard AU - Adamu, Haileeyesus AU - Xiao, Lihua AD - Department of Medical Laboratory Science, University of Benin, Benin City, Nigeria; Department of Animal and Environmental Biology, University of Benin, Benin City, Nigeria; School of Medical Laboratory Sciences, University of Benin Teaching Hospital, Benin City, Nigeria; Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Diseases Control and Prevention, Atlanta, Georgia, lxiao@cdc.gov PY - 2013 SP - 157 EP - 161 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 89 IS - 1 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Felis KW - Enterocytozoon bieneusi KW - Genotypes KW - Infection KW - Flow cytometry KW - Blood KW - CD4 antigen KW - DNA sequencing KW - Human immunodeficiency virus KW - highly active antiretroviral therapy KW - Cryptosporidium KW - Polymerase chain reaction KW - Feces KW - Developing countries KW - V 22360:AIDS and HIV KW - K 03310:Genetics & Taxonomy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1647004293?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Unusual+Enterocytozoon+bieneusi+Genotypes+and+Cryptosporidium+hominis+Subtypes+in+HIV-Infected+Patients+on+Highly+Active+Antiretroviral+Therapy&rft.au=Akinbo%2C+Frederick+O%3BOkaka%2C+Christopher+E%3BOmoregie%2C+Richard%3BAdamu%2C+Haileeyesus%3BXiao%2C+Lihua&rft.aulast=Akinbo&rft.aufirst=Frederick&rft.date=2013-07-01&rft.volume=89&rft.issue=1&rft.spage=157&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.12-0635 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2016-01-06 N1 - SubjectsTermNotLitGenreText - Flow cytometry; Blood; DNA sequencing; CD4 antigen; highly active antiretroviral therapy; Polymerase chain reaction; Genotypes; Infection; Feces; Developing countries; Felis; Human immunodeficiency virus; Cryptosporidium; Enterocytozoon bieneusi DO - http://dx.doi.org/10.4269/ajtmh.12-0635 ER - TY - JOUR T1 - HIV Prevention Programs Delivered by Community-Based Organizations to Young Transgender Persons of Color: Lessons Learned to Improve Future Program Implementation AN - 1463025716; 201309348 AB - Transgender communities in the United States experience high rates of HIV infection. To address the HIV prevention needs of transgender persons of color aged 13 to 24, the Centers for Disease Control and Prevention funded community-based organizations (CBOs) to implement programs for this population. The purpose of this article is to identify programmatic successes and challenges encountered by 5 CBOs implementing programs in high-HIV-prevalence U.S. cities. Annual progress reports were analyzed using a qualitative content analysis approach. Seven themes were identified: collaborations/partnerships, engaging the community, expanded services, safe space, recruitment and retention, staffing, and social inequality and transphobia. Lessons learned are identified for improving future program implementation. Adapted from the source document. JF - International Journal of Transgenderism AU - Gelaude, Deborah J AU - Sovine, Melanie L AU - Swayzer, Robert, III AU - Herbst, Jeffrey H AD - Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia dgelaude@cdc.gov Y1 - 2013/07// PY - 2013 DA - July 2013 SP - 127 EP - 139 PB - Taylor & Francis, Philadelphia PA VL - 14 IS - 3 SN - 1553-2739, 1553-2739 KW - Attrition KW - Transsexuality KW - Program Implementation KW - Acquired Immune Deficiency Syndrome KW - Recruitment KW - Social Inequality KW - Community Services KW - Health Care Services KW - Community Organizations KW - article KW - 6126: acquired immune deficiency syndrome (AIDS) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1463025716?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocialservices&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Transgenderism&rft.atitle=HIV+Prevention+Programs+Delivered+by+Community-Based+Organizations+to+Young+Transgender+Persons+of+Color%3A+Lessons+Learned+to+Improve+Future+Program+Implementation&rft.au=Gelaude%2C+Deborah+J%3BSovine%2C+Melanie+L%3BSwayzer%2C+Robert%2C+III%3BHerbst%2C+Jeffrey+H&rft.aulast=Gelaude&rft.aufirst=Deborah&rft.date=2013-07-01&rft.volume=14&rft.issue=3&rft.spage=127&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Transgenderism&rft.issn=15532739&rft_id=info:doi/10.1080%2F15532739.2013.824846 LA - English DB - Social Services Abstracts N1 - Date revised - 2013-12-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Community Services; Acquired Immune Deficiency Syndrome; Transsexuality; Community Organizations; Program Implementation; Attrition; Social Inequality; Health Care Services; Recruitment DO - http://dx.doi.org/10.1080/15532739.2013.824846 ER - TY - JOUR T1 - Vaccinations for international travellers travelling from Greece AN - 1458547567; 18322511 AB - The aim of this prospective, questionnaire-based study is to assess pre-travel vaccinations for international travellers who receive pre-travel advice in Greece. A total of 2494 travellers were studied from January 1, 2009 through December 31, 2010. Travellers sought pre-travel advice at a median of 16 days (range: 0-349 days) before departure. Sub-Saharan Africa was the most common destination (34.7%). Most travellers (60.8%) travelled for <1 month, for recreation purposes (58.9%), stayed in hotels (65.3%), and in urban areas (53.6%). Yellow fever, tetravalent meningococcal, typhoid fever, cholera, and rabies vaccines were administered to 1629 (65.3%), 666 (26.7%), 615 (24.7%), 28 (1.1%), and/or 12 (0.5%) travellers, respectively. Of those who received Yellow fever vaccine, 737 (45.2%) travelled to sub-Saharan Africa, 332 (20.4%) travelled to South America, 949 (58.3%) stayed for short term, and 762 (46.8%) stayed in urban areas. Of the 1629 travellers vaccinated against Yellow fever, 150 (9.2%) and 226 (13.8%) travelled to areas of sub-Saharan Africa and South America respectively, where the vaccine is not or generally not recommended. Of those travellers who received meningococcal vaccine, 327 (49.1%) travelled to the Middle East for the Hajj, 251 (29%) travelled to sub-Saharan Africa, 410 (61.6%) for short term, and 540 (64.4%) stayed in urban areas. Of those travellers who received typhoid vaccine, 241 (39.2%) travelled to sub-Saharan Africa, 78 (12.7%) to the Indian subcontinent, 234 (38%) for short term, and 419 (68.1%) stayed in urban areas. Regarding routine vaccines, tetanus-diphtheria, poliomyelitis, and measles-mumps-rubella vaccines were administered to 707 (28.3%), 639 (25.6%) and/or 149 (6%) travellers, respectively. Of those to whom poliomyelitis vaccine was recommended, 295 (46.2%) and 137 (21.4%) travelled to sub-Saharan Africa and the Middle East, respectively, and 362 (56.7%) travelled for short term. In conclusion, this study revealed that there is a need for more selective vaccine recommendations for travellers to developing countries, taking under consideration travellers and travel characteristics as well. Strategies to target travel health consultants should be developed in order to increase awareness in travel health issues. JF - Travel Medicine and Infectious Disease AU - Pavli, Androula AU - Spilioti, Athina AU - Lymperi, Ioanna AU - Katerelos, Panagiotis AU - Maltezou, Helena C AD - Travel Medicine Office, Hellenic Center for Disease Control and Prevention, Athens, Greece Y1 - 2013/07// PY - 2013 DA - July 2013 SP - 225 EP - 230 PB - Elsevier VL - 11 IS - 4 SN - 1477-8939, 1477-8939 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources KW - Pre-travel KW - Vaccination KW - Yellow fever KW - Typhoid KW - Rabies KW - Poliovirus KW - Consultants KW - Pathogenic bacteria KW - Bacterial diseases KW - Disease control KW - Neisseria meningitidis KW - MED, Greece KW - ASW, South America KW - Recreation KW - Infectious diseases KW - Africa KW - Vaccines KW - Developing countries KW - Middle East KW - Q1 08604:Stock assessment and management KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1458547567?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Travel+Medicine+and+Infectious+Disease&rft.atitle=Vaccinations+for+international+travellers+travelling+from+Greece&rft.au=Pavli%2C+Androula%3BSpilioti%2C+Athina%3BLymperi%2C+Ioanna%3BKaterelos%2C+Panagiotis%3BMaltezou%2C+Helena+C&rft.aulast=Pavli&rft.aufirst=Androula&rft.date=2013-07-01&rft.volume=11&rft.issue=4&rft.spage=225&rft.isbn=&rft.btitle=&rft.title=Travel+Medicine+and+Infectious+Disease&rft.issn=14778939&rft_id=info:doi/10.1016%2Fj.tmaid.2012.11.007 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-11-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Consultants; Recreation; Pathogenic bacteria; Infectious diseases; Bacterial diseases; Disease control; Vaccines; Developing countries; Vaccination; Poliovirus; Neisseria meningitidis; MED, Greece; ASW, South America; Africa; Middle East DO - http://dx.doi.org/10.1016/j.tmaid.2012.11.007 ER - TY - JOUR T1 - Comparison of the Levels of Infectious Virus in Respirable Aerosols Exhaled by Ferrets Infected with Influenza Viruses Exhibiting Diverse Transmissibility Phenotypes AN - 1412519455; 18253709 AB - Influenza viruses pose a major public health burden to communities around the world by causing respiratory infections that can be highly contagious and spread rapidly through the population. Despite extensive research on influenza viruses, the modes of transmission occurring most often among humans are not entirely clear. Contributing to this knowledge gap is the lack of an understanding of the levels of infectious virus present in respirable aerosols exhaled from infected hosts. Here, we used the ferret model to evaluate aerosol shedding patterns and measure the amount of infectious virus present in exhaled respirable aerosols. By comparing these parameters among a panel of human and avian influenza viruses exhibiting diverse respiratory droplet transmission efficiencies, we are able to report that ferrets infected by highly transmissible influenza viruses exhale a greater number of aerosol particles and more infectious virus within respirable aerosols than ferrets infected by influenza viruses that do not readily transmit. Our findings improve our understanding of the ferret transmission model and provide support for the potential for influenza virus aerosol transmission. JF - Journal of Virology AU - Gustin, Kortney M AU - Katz, Jacqueline M AU - Tumpey, Terrence M AU - Maines, Taronna R Y1 - 2013/07// PY - 2013 DA - Jul 2013 SP - 7864 EP - 7873 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 87 IS - 14 SN - 0022-538X, 0022-538X KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Aerosols KW - Viruses KW - Particulates KW - Infection KW - Models KW - Public health KW - Influenza KW - Fowl plague KW - Influenza virus KW - Mustela KW - H 1000:Occupational Safety and Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1412519455?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Virology&rft.atitle=Comparison+of+the+Levels+of+Infectious+Virus+in+Respirable+Aerosols+Exhaled+by+Ferrets+Infected+with+Influenza+Viruses+Exhibiting+Diverse+Transmissibility+Phenotypes&rft.au=Gustin%2C+Kortney+M%3BKatz%2C+Jacqueline+M%3BTumpey%2C+Terrence+M%3BMaines%2C+Taronna+R&rft.aulast=Gustin&rft.aufirst=Kortney&rft.date=2013-07-01&rft.volume=87&rft.issue=14&rft.spage=7864&rft.isbn=&rft.btitle=&rft.title=Journal+of+Virology&rft.issn=0022538X&rft_id=info:doi/10.1128%2FJVI.00719-13 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-07-01 N1 - Number of references - 37 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Fowl plague; Aerosols; Infection; Public health; Models; Influenza; Viruses; Particulates; Influenza virus; Mustela DO - http://dx.doi.org/10.1128/JVI.00719-13 ER - TY - JOUR T1 - Chemical analysis of Alaskan Iq'mik smokeless tobacco. AN - 1369235314; 23288872 AB - Iq'mik, a form of smokeless tobacco (ST), is traditionally used by Cup'ik and Yup'ik Eskimo people of western Alaska. Iq'mik is sometimes incorrectly considered to be a healthier alternative to smoking because its ingredients are perceived as "natural." Our chemical characterization of iq'mik shows that iq'mik is not a safe alternative to smoking or other ST use. We measured nicotine and pH levels of tobacco and ash used to prepare iq'mik. We also characterized levels of toxins which are known to be present in ST including tobacco-specific nitrosamines (TSNAs) and polycyclic aromatic hydrocarbons (PAHs) using chromatographic separations coupled with isotope dilution mass spectrometry. Nicotine content in the iq'mik tobacco was very high, ranging from 35 to 43 mg/g, with a mean of 39 mg/g. The pH of the iq'mik tobacco-ash mixture was 11, an extremely high level compared with most ST products. High levels of PAHs were seen in the fire-cured tobacco samples with a benzo[a]pyrene level of 87 ng/g. Average TSNA levels in the tobacco were 34, 2,700, and 340 ng/g for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), N'-nitrosonornicotine (NNN), and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), respectively. Iq'mik contains high levels of the more easily absorbed unionized nicotine as well as known carcinogenic TSNAs and PAHs. The perception that iq'mik is less hazardous than other tobacco products due to the use of "natural" ingredients is not warranted. This chemical characterization of iq'mik gives a better understanding of the risk of possible adverse health effects of its use. JF - Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco AU - Hearn, Bryan A AU - Renner, Caroline C AU - Ding, Yan S AU - Vaughan-Watson, Christina AU - Stanfill, Stephen B AU - Zhang, Liqin AU - Polzin, Gregory M AU - Ashley, David L AU - Watson, Clifford H AD - Centers for Disease Control and Prevention, Office of Noncommunicable Diseases, Injury and Environmental Health, Atlanta, GA 30341, USA. bhearn@cdc.gov Y1 - 2013/07// PY - 2013 DA - July 2013 SP - 1283 EP - 1288 VL - 15 IS - 7 KW - Nitrosamines KW - 0 KW - Polycyclic Aromatic Hydrocarbons KW - Benzo(a)pyrene KW - 3417WMA06D KW - Nicotine KW - 6M3C89ZY6R KW - 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone KW - 7S395EDO61 KW - N'-nitrosonornicotine KW - X656TZ86DX KW - Index Medicus KW - Inuits KW - Benzo(a)pyrene -- analysis KW - Hydrogen-Ion Concentration KW - Humans KW - Alaska KW - Nicotine -- analysis KW - Polycyclic Aromatic Hydrocarbons -- analysis KW - Nitrosamines -- analysis KW - Tobacco, Smokeless -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1369235314?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Nicotine+%26+tobacco+research+%3A+official+journal+of+the+Society+for+Research+on+Nicotine+and+Tobacco&rft.atitle=Chemical+analysis+of+Alaskan+Iq%27mik+smokeless+tobacco.&rft.au=Hearn%2C+Bryan+A%3BRenner%2C+Caroline+C%3BDing%2C+Yan+S%3BVaughan-Watson%2C+Christina%3BStanfill%2C+Stephen+B%3BZhang%2C+Liqin%3BPolzin%2C+Gregory+M%3BAshley%2C+David+L%3BWatson%2C+Clifford+H&rft.aulast=Hearn&rft.aufirst=Bryan&rft.date=2013-07-01&rft.volume=15&rft.issue=7&rft.spage=1283&rft.isbn=&rft.btitle=&rft.title=Nicotine+%26+tobacco+research+%3A+official+journal+of+the+Society+for+Research+on+Nicotine+and+Tobacco&rft.issn=1469-994X&rft_id=info:doi/10.1093%2Fntr%2Fnts270 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2014-01-27 N1 - Date created - 2013-06-17 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1093/ntr/nts270 ER - TY - JOUR T1 - Factors associated with human papillomavirus vaccination among young adult women in the United States AN - 1443367214; 18663145 AB - Background: Human papillomavirus (HPV) vaccination is recommended to protect against HPV-related diseases. Objective: To estimate HPV vaccine coverage and assess factors associated with vaccine awareness, initiation and receipt of 3 doses among women age 18-30 years. Methods: Data from the 2010 National Health Interview Survey were analyzed to assess associations of HPV vaccination among women age 18-26 (n = 1866) and 27-30 years (n = 1028) with previous HPV exposure, cervical cancer screening and selected demographic, health care and behavioral characteristics using bivariate analysis and multivariable logistic regression. Results: Overall, 23.2% of women age 18-26 and 6.7% of women age 27-30 years reported receiving at least 1 dose of HPV vaccine. In multivariable analyses among women age 18-26 years, not being married, having a regular physician, seeing a physician or obstetrician/gynecologist in the past year, influenza vaccination in the past year, and receipt of other recommended vaccines were associated with HPV vaccination. One-third of unvaccinated women age 18-26 years (n = 490) were interested in receiving HPV vaccine. Among women who were not interested in receiving HPV vaccine (n = 920), the main reasons reported included: not needing the vaccine (41.3%); concerns about safety of the vaccine (12.5%); not knowing enough about the vaccine (11.9%); not being sexually active (8.2%); a doctor not recommending the vaccine (7.6%); and already having HPV (2.7%). Among women with health insurance, 10 or more physician contacts within the past year and no contraindications, 74.5% reported not receiving HPV vaccine. Conclusions: HPV vaccination coverage among women age 18-26 years remains low. Opportunities to vaccinate are missed. Healthcare providers can play an important role in educating young women about HPV and encouraging vaccination. Successful public health and educational interventions will need to address physician attitudes and practice patterns and other factors that influence vaccination behaviors. JF - Vaccine AU - Williams, W W AU - Lu, P-J AU - Saraiya, M AU - Yankey, D AU - Dorell, C AU - Rodriguez, J L AU - Kepka, D AU - Markowitz, LE AD - National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Mail Stop A-19, Atlanta, GA 30333, United States, www.1@cdc.gov Y1 - 2013/06/19/ PY - 2013 DA - 2013 Jun 19 SP - 2937 EP - 2946 VL - 31 IS - 28 SN - 0264-410X, 0264-410X KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts; Immunology Abstracts KW - Age KW - USA KW - Vaccines KW - Human papillomavirus KW - V:22400 KW - F:06915 KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1443367214?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Factors+associated+with+human+papillomavirus+vaccination+among+young+adult+women+in+the+United+States&rft.au=Williams%2C+W+W%3BLu%2C+P-J%3BSaraiya%2C+M%3BYankey%2C+D%3BDorell%2C+C%3BRodriguez%2C+J+L%3BKepka%2C+D%3BMarkowitz%2C+LE&rft.aulast=Williams&rft.aufirst=W&rft.date=2013-06-19&rft.volume=31&rft.issue=28&rft.spage=2937&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-10-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Vaccines; Human papillomavirus; USA ER - TY - JOUR T1 - Herpes simplex virus type 2 incidence and associated risk factors among female sex workers in a high HIV-prevalence area of China AN - 1712575757; PQ0001965656 AB - Herpes simplex virus type 2 (HSV-2) can contribute to the spread of HIV. From March 2006 to November 2009, female sex workers (FSWs) in Yunnan, China were recruited into an open cohort study to determine incidence and risk factors for HSV-2 acquisition. Participants were interviewed and tested for HSV-2 and other sexually transmitted infections (STIs) every six months. A multivariate Cox proportional hazards regression model with time-dependent variables was used to measure associations with HSV-2 acquisition. In 3.5 years, 83 incident cases of HSV-2 infection were diagnosed, yielding an overall incidence of 21.9 per 100 person years (PY) (95% confidence interval [CI], 17.8-26.3). Working in higher risk commercial sex venues, current Neisseria gonorrhoeae infection, age of sexual debut <18 years and lack of a regular sex partner were independent factors associated with HSV-2 acquisition. The high incidence of HSV-2 suggests that prevention methods for HIV/STI control are urgently needed. JF - International Journal of STD & AIDS AU - Wang, H AU - Reilly, K H AU - Smith, M K AU - Brown, K AU - Jin, X AU - Xu, J AU - Ding, G AU - Zang, C AU - Wang, J AU - Wang, N AD - Chinese Center for Disease Control and Prevention, 27 Nanwei Rd, Beijing 100050, wangnbj@163.com PY - 2013 SP - 441 EP - 446 PB - Sage Publications, Inc., 2455 Teller Road Thousand Oaks CA 91320 United States VL - 24 IS - 6 SN - 0956-4624, 0956-4624 KW - Health & Safety Science Abstracts; Risk Abstracts; Virology & AIDS Abstracts KW - HIV KW - sexually transmitted infections KW - Herpes simplex virus type 2 KW - HSV-2 incidence KW - female sex workers KW - Neisseria gonorrhoeae KW - China KW - Acquired immune deficiency syndrome KW - Age KW - Prostitution KW - Herpes simplex virus 2 KW - Infection KW - Models KW - Prevention KW - Currents KW - Infectious diseases KW - Human immunodeficiency virus KW - Risk factors KW - Regression analysis KW - China, People's Rep. KW - Females KW - Sexually transmitted diseases KW - Sex KW - V 22360:AIDS and HIV KW - H 1000:Occupational Safety and Health KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1712575757?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+STD+%26+AIDS&rft.atitle=Herpes+simplex+virus+type+2+incidence+and+associated+risk+factors+among+female+sex+workers+in+a+high+HIV-prevalence+area+of+China&rft.au=Wang%2C+H%3BReilly%2C+K+H%3BSmith%2C+M+K%3BBrown%2C+K%3BJin%2C+X%3BXu%2C+J%3BDing%2C+G%3BZang%2C+C%3BWang%2C+J%3BWang%2C+N&rft.aulast=Wang&rft.aufirst=H&rft.date=2013-06-01&rft.volume=24&rft.issue=6&rft.spage=441&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+STD+%26+AIDS&rft.issn=09564624&rft_id=info:doi/10.1177%2F0956462412472800 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-09-01 N1 - Last updated - 2015-12-23 N1 - SubjectsTermNotLitGenreText - Age; Risk factors; Regression analysis; Prostitution; Infection; Models; Sex; Currents; Prevention; Acquired immune deficiency syndrome; Infectious diseases; Human immunodeficiency virus; Females; Sexually transmitted diseases; Herpes simplex virus 2; Neisseria gonorrhoeae; China, People's Rep. DO - http://dx.doi.org/10.1177/0956462412472800 ER - TY - JOUR T1 - Prevalence of hearing loss in the United States by industry AN - 1560138258; 19416443 AB - Background Twenty-two million workers are exposed to hazardous noise in the United States. The purpose of this study is to estimate the prevalence of hearing loss among U.S. industries. Methods We examined 2000-2008 audiograms for male and female workers ages 18-65, who had higher occupational noise exposures than the general population. Prevalence and adjusted prevalence ratios (PRs) for hearing loss were estimated and compared across industries. Results In our sample, 18% of workers had hearing loss. When compared with the Couriers and Messengers industry sub-sector, workers employed in Mining (PR=1.65, CI=1.57-1.73), Wood Product Manufacturing (PR=1.65, CL=1.61-1.70), Construction of Buildings (PR=1.52, CI=1.45-1.59), and Real Estate and Rental and Leasing (PR=1.59, CL=1.51-1.68) had higher risks for hearing loss. Conclusions Workers in the Mining, Manufacturing, and Construction industries need better engineering controls for noise and stronger hearing conservation strategies. More hearing loss research is also needed within traditional "low-risk" industries like Real Estate. Am. J. Ind. Med. 56:670-681, 2013. copyright 2012 Wiley Periodicals, Inc. JF - American Journal of Industrial Medicine AU - Masterson, Elizabeth A AU - Tak, SangWoo AU - Themann, Christa L AU - Wall, David K AU - Groenewold, Matthew R AU - Deddens, James A AU - Calvert, Geoffrey M AD - Massachusetts Department of Public Health, Boston, Massachusetts., emasterson@cdc.gov Y1 - 2013/06// PY - 2013 DA - Jun 2013 SP - 670 EP - 681 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 56 IS - 6 SN - 0271-3586, 0271-3586 KW - Risk Abstracts; Health & Safety Science Abstracts KW - occupational hearing loss KW - hearing impairment KW - hazardous noise KW - noise-induced hearing loss KW - occupational noise exposure standard KW - USA KW - Age KW - Noise levels KW - Wood KW - Hearing loss KW - Mining KW - Buildings KW - Construction industry KW - H 1000:Occupational Safety and Health KW - R2 23050:Environment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1560138258?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Prevalence+of+hearing+loss+in+the+United+States+by+industry&rft.au=Masterson%2C+Elizabeth+A%3BTak%2C+SangWoo%3BThemann%2C+Christa+L%3BWall%2C+David+K%3BGroenewold%2C+Matthew+R%3BDeddens%2C+James+A%3BCalvert%2C+Geoffrey+M&rft.aulast=Masterson&rft.aufirst=Elizabeth&rft.date=2013-06-01&rft.volume=56&rft.issue=6&rft.spage=670&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=02713586&rft_id=info:doi/10.1002%2Fajim.22082 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Last updated - 2014-10-02 N1 - SubjectsTermNotLitGenreText - Age; Noise levels; Wood; Mining; Hearing loss; Buildings; Construction industry; USA DO - http://dx.doi.org/10.1002/ajim.22082 ER - TY - JOUR T1 - HIV Diagnoses and Prevalence in the Southern Region of the United States, 2007-2010 AN - 1429652956; 2011-482168 AB - On a number of leading health indicators, including HIV disease, individuals in the southern states of the United States fare worse than those in other regions. We analyzed data on adults and adolescents diagnosed with HIV infection through December 2010, and reported to the Centers for Disease Control and Prevention (CDC) through June 2011 from 46 states with confidential name-based HIV reporting since January 2007 to describe the impact of HIV in the South. In 2010 46.0 % of all new diagnoses of HIV infection occurred in the South. Compared to other regions, a higher percentage of diagnoses in the South were among women (23.8 %), blacks/African Americans (57.2 %), and among those in the heterosexual contact category (15.0 % for males; 88.5 % for females). From 2007 to 2010 the estimated number and rate of diagnoses of HIV infection decreased significantly in the South overall (estimated annual percentage change [EAPC] = -1.5 % [95 %CI -2.3 %, -0.7 %] and -2.1 % [95 % CI -4.0 %, -0.2 %], respectively) and among most groups of women, but there was no change in the number or rate of diagnoses of HIV infection among men overall. Significant decreases in men 30-39 and 40-49 years of age were offset by increases in young men 13-19 and 20-29 years of age. A continued focus on this area of high HIV burden is needed to yield success in the fight against HIV disease. Adapted from the source document. JF - Journal of Community Health AU - Prejean, Joseph AU - Tang, Tian AU - Irene Hall, H AD - Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention jprejean@cdc.gov Y1 - 2013/06// PY - 2013 DA - June 2013 SP - 414 EP - 426 PB - Springer, New York NY VL - 38 IS - 3 SN - 0094-5145, 0094-5145 KW - Health conditions and policy - Diseases and disorders KW - Population groups, population policy, and demographics - Men KW - Population groups, population policy, and demographics - Women KW - Population groups, population policy, and demographics - National, ethnic, and minority groups KW - Social conditions and policy - Social values KW - Population groups, population policy, and demographics - Demography and census KW - United States KW - Heterosexuals KW - Blacks KW - Men KW - Human immunodeficiency virus KW - Women KW - Adults KW - Diseases KW - Success KW - Fares KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1429652956?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Community+Health&rft.atitle=HIV+Diagnoses+and+Prevalence+in+the+Southern+Region+of+the+United+States%2C+2007-2010&rft.au=Prejean%2C+Joseph%3BTang%2C+Tian%3BIrene+Hall%2C+H&rft.aulast=Prejean&rft.aufirst=Joseph&rft.date=2013-06-01&rft.volume=38&rft.issue=3&rft.spage=414&rft.isbn=&rft.btitle=&rft.title=Journal+of+Community+Health&rft.issn=00945145&rft_id=info:doi/10.1007%2Fs10900-012-9633-1 LA - English DB - PAIS Index N1 - Date revised - 2013-09-01 N1 - Last updated - 2016-09-28 N1 - CODEN - JCMHBR N1 - SubjectsTermNotLitGenreText - Human immunodeficiency virus; Men; Diseases; Women; United States; Blacks; Fares; Success; Heterosexuals; Adults DO - http://dx.doi.org/10.1007/s10900-012-9633-1 ER - TY - JOUR T1 - Large-Scale Radiation Emergencies: What Can Medical Health Physicists Do? AN - 1419360828; 18278090 AB - In case of a large-scale radiation emergency, response agencies at all levels of government as well as healthcare systems will face many challenging issues trying to meet the needs of the affected population in every community. A critical scare resource in such a scenario is radiation safety expertise. Medical health physicists can play a pivotal role in preparing their hospitals and their communities, and they can contribute significantly during response to such emergencies. To that end, medical health physicists need to have an awareness of the overall public health and medical response to radiation emergencies, know their roles within their organization's emergency response plan, and know what training and planning resources are available to them. Furthermore, radiation protection professionals should be aware of and participate in health volunteer opportunities in their communities and contribute their expertise to improve their community's resiliency and radiation emergency preparedness. JF - Transactions of the American Nuclear Society AU - Ansari, Armin AD - Centers for Disease Control and Prevention, 4770 Buford Highway NE, Atlanta, GA, 30341, aansari@cdc.gov Y1 - 2013/06// PY - 2013 DA - Jun 2013 SP - 38 EP - 39 PB - American Nuclear Society, Inc. VL - 108 SN - 0003-018X, 0003-018X KW - Health & Safety Science Abstracts KW - Health care KW - Training KW - Emergency preparedness KW - Public health KW - Hospitals KW - H 6000:Natural Disasters/Civil Defense/Emergency Management UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1419360828?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Transactions+of+the+American+Nuclear+Society&rft.atitle=Large-Scale+Radiation+Emergencies%3A+What+Can+Medical+Health+Physicists+Do%3F&rft.au=Ansari%2C+Armin&rft.aulast=Ansari&rft.aufirst=Armin&rft.date=2013-06-01&rft.volume=108&rft.issue=&rft.spage=38&rft.isbn=&rft.btitle=&rft.title=Transactions+of+the+American+Nuclear+Society&rft.issn=0003018X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-08-01 N1 - Number of references - 8 N1 - Last updated - 2015-04-09 N1 - SubjectsTermNotLitGenreText - Health care; Training; Emergency preparedness; Hospitals; Public health ER - TY - JOUR T1 - Real-time modelling used for outbreak management during a cholera epidemic, Haiti, 2010-2011 AN - 1372056894; 18144552 AB - The emergence of epidemic cholera in post-earthquake Haiti portended a public health disaster of uncertain magnitude. In order to coordinate relief efforts in an environment with limited healthcare infrastructure and stretched resources, timely and realistic projections of the extent of the cholera outbreak were crucial. Projections were shared with Government and partner organizations beginning 5 days after the first reported case and were updated using progressively more advanced methods as more surveillance data became available. The first projection estimated that 105 000 cholera cases would occur in the first year. Subsequent projections using different methods estimated up to 652 000 cases and 163 000-247 000 hospitalizations during the first year. Current surveillance data show these projections to have provided reasonable approximations of the observed epidemic. Providing the real-time projections allowed Haitian ministries and external aid organizations to better plan and implement response measures during the evolving epidemic. JF - Epidemiology and Infection AU - Abrams, J Y AU - Copeland, J R AU - Tauxe, R V AU - Date, Ka AU - Belay, Ed AU - Mody, R K AU - Mintz, Ed AD - Centers for Disease Control and Prevention, Atlanta, GA, USA, JAbrams@cdc.gov Y1 - 2013/06// PY - 2013 DA - June 2013 SP - 1276 EP - 1285 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 141 IS - 6 SN - 0950-2688, 0950-2688 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts KW - New records KW - Data processing KW - Epidemics KW - Pathogenic bacteria KW - Bacterial diseases KW - Surveillance and enforcement KW - Disasters KW - Public health KW - Infrastructure KW - Health care KW - Epidemiology KW - Cholera KW - Outbreaks KW - ASW, Caribbean Sea, Greater Antilles, Haiti KW - Modelling KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - Q1 08604:Stock assessment and management KW - J 02400:Human Diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1372056894?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Real-time+modelling+used+for+outbreak+management+during+a+cholera+epidemic%2C+Haiti%2C+2010-2011&rft.au=Abrams%2C+J+Y%3BCopeland%2C+J+R%3BTauxe%2C+R+V%3BDate%2C+Ka%3BBelay%2C+Ed%3BMody%2C+R+K%3BMintz%2C+Ed&rft.aulast=Abrams&rft.aufirst=J&rft.date=2013-06-01&rft.volume=141&rft.issue=6&rft.spage=1276&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268812001793 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-06-01 N1 - Number of references - 28 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - New records; Epidemics; Epidemiology; Pathogenic bacteria; Bacterial diseases; Disasters; Surveillance and enforcement; Modelling; Public health; Data processing; Cholera; Infrastructure; Health care; Outbreaks; ASW, Caribbean Sea, Greater Antilles, Haiti DO - http://dx.doi.org/10.1017/S0950268812001793 ER - TY - JOUR T1 - HIV Transmission in the United States: Considerations of Viral Load, Risk Behavior, and Health Disparities AN - 1367493739; 18090585 AB - Ongoing HIV transmission is related to prevalence, risk behavior and viral load among persons with HIV. We assessed the contribution of these factors to HIV transmission with transmission rate models and data reported to National HIV Surveillance and published rates of risk behavior. We also estimated numbers of persons with risk behaviors and unsuppressed viral load among sexual risk groups. The transmission rate is higher considering risk behavior (18.5 infections per 100 people with HIV) than that attributed to unsuppressed viral load (4.6). Since persons without risk behavior or suppressed viral load presumably transmit HIV at very low rates, transmission can be attributed to a combination of these factors (28.9). Service needs are greatest for MSM; their number with unsuppressed viral load engaging in unprotected discordant sex was 8 times the number of male heterosexuals and more than twice the number of female heterosexuals with high-risk transmission potential. While all persons with HIV need optimal care, treatment as prevention is most relevant when risk behavior is present among persons with unsuppressed HIV viral load. JF - AIDS and Behavior AU - Hall, HIrene AU - Holtgrave, David R AU - Tang, Tian AU - Rhodes, Philip AD - Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control & Prevention, 1600 Clifton Road NE, MS E-47, Atlanta, GA, 30333, USA, ixh1@cdc.gov Y1 - 2013/06// PY - 2013 DA - Jun 2013 SP - 1632 EP - 1636 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 17 IS - 5 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - Acquired immune deficiency syndrome KW - Data processing KW - Infection KW - Disease transmission KW - Models KW - USA KW - Prevention KW - Behavior KW - Human immunodeficiency virus KW - Risk factors KW - Risk groups KW - Sex KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1367493739?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=HIV+Transmission+in+the+United+States%3A+Considerations+of+Viral+Load%2C+Risk+Behavior%2C+and+Health+Disparities&rft.au=Hall%2C+HIrene%3BHoltgrave%2C+David+R%3BTang%2C+Tian%3BRhodes%2C+Philip&rft.aulast=Hall&rft.aufirst=HIrene&rft.date=2013-06-01&rft.volume=17&rft.issue=5&rft.spage=1632&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-013-0426-z LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-06-01 N1 - Number of references - 25 N1 - Last updated - 2013-07-26 N1 - SubjectsTermNotLitGenreText - Data processing; Risk factors; Risk groups; Infection; Models; Sex; Disease transmission; Prevention; Acquired immune deficiency syndrome; Behavior; Human immunodeficiency virus; USA DO - http://dx.doi.org/10.1007/s10461-013-0426-z ER - TY - JOUR T1 - Performance of Cepheid super( registered ) Xpert MTB/RIF super( registered ) and TB-Biochip super( registered ) MDR in two regions of Russia with a high prevalence of drug-resistant tuberculosis AN - 1367489275; 18062152 AB - The purpose of this study was to assess the performance of Cepheid registered Xpert MTB/RIF registered ("Xpert") and TB-Biochip registered MDR ("TB-Biochip"). Sputum specimens from adults with presumptive tuberculosis (TB) were homogenized and split for: (1) direct Xpert and microscopy, and (2) concentration for Xpert, microscopy, culture [Lowenstein-Jensen (LJ) solid media and Mycobacteria Growth Indicator Tube registered (MGIT)], indirect drug susceptibility testing (DST) using the absolute concentration method and MGIT, and TB-Biochip. In total, 109 of 238 (45.8 %) specimens were culture-positive for Mycobacterium tuberculosis complex (MTBC), and, of these, 67 isolates were rifampicin resistant (RIF-R) by phenotypic DST and 64/67 (95.5 %) were isoniazid resistant (INH-R). Compared to culture of the same specimen, a single direct Xpert was more sensitive for detecting MTBC [95.3 %, 95 % confidence interval (CI), 90.0-98.3 %] than direct (59.6 %, 95 % CI, 50.2-68.5 %) or concentrated smear (85.3 %, 95 % CI, 77.7-91.1 %) or LJ culture (80.8 %, 95 % CI, 72.4-87.5 %); the specificity was 86.0 % (95 % CI, 78.9-91.3 %). Compared with MGIT DST, Xpert correctly identified 98.2 % (95 % CI, 91.5-99.9 %) of RIF-R and 95.5 % (95 % CI, 85.8-99.2 %) of RIF-susceptible (RIF-S) specimens. In a subset of 104 specimens, the sensitivity of TB-Biochip for MTBC detection compared to culture was 97.3 % (95 % CI, 91.0-99.5 %); the specificity was 78.1 % (95 % CI, 61.5-89.9 %). TB-Biochip correctly identified 100 % (95 % CI, 94.2-100 %) of RIF-R, 94.7 % (95 % CI, 76.7-99.7 %) of RIF-S, 98.2 % (95 % CI, 91.4-99.9 %) of INH-R, and 78.6 % (95 % CI, 52.1-94.2 %) of INH-S specimens compared to MGIT DST. Xpert and Biochip were similar in accuracy for detecting MTBC and RIF resistance compared to conventional culture methods. JF - European Journal of Clinical Microbiology & Infectious Diseases AU - Kurbatova, E V AU - Kaminski, DA AU - Erokhin, V V AU - Volchenkov, G V AU - Andreevskaya, S N AU - Chernousova, L N AU - Demikhova, O V AU - Ershova, J V AU - Kaunetis, N V AU - Kuznetsova, T A AU - Larionova, EE AU - Smirnova, T G AU - Somova, T R AU - Vasilieva, IA AU - Vorobieva, A V AU - Zolkina, S S AU - Cegielski, J P AD - The U.S. Centers for Disease Control and Prevention, CDC, Atlanta, GA, USA, dkaminski@cdc.gov Y1 - 2013/06// PY - 2013 DA - Jun 2013 SP - 735 EP - 743 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 32 IS - 6 SN - 0934-9723, 0934-9723 KW - Microbiology Abstracts B: Bacteriology KW - Rifampin KW - biochips KW - Drug resistance KW - Microscopy KW - Tuberculosis KW - Sputum KW - Drugs KW - Media (culture) KW - Mycobacterium tuberculosis KW - Isoniazid KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1367489275?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=European+Journal+of+Clinical+Microbiology+%26+Infectious+Diseases&rft.atitle=Performance+of+Cepheid+super%28+registered+%29+Xpert+MTB%2FRIF+super%28+registered+%29+and+TB-Biochip+super%28+registered+%29+MDR+in+two+regions+of+Russia+with+a+high+prevalence+of+drug-resistant+tuberculosis&rft.au=Kurbatova%2C+E+V%3BKaminski%2C+DA%3BErokhin%2C+V+V%3BVolchenkov%2C+G+V%3BAndreevskaya%2C+S+N%3BChernousova%2C+L+N%3BDemikhova%2C+O+V%3BErshova%2C+J+V%3BKaunetis%2C+N+V%3BKuznetsova%2C+T+A%3BLarionova%2C+EE%3BSmirnova%2C+T+G%3BSomova%2C+T+R%3BVasilieva%2C+IA%3BVorobieva%2C+A+V%3BZolkina%2C+S+S%3BCegielski%2C+J+P&rft.aulast=Kurbatova&rft.aufirst=E&rft.date=2013-06-01&rft.volume=32&rft.issue=6&rft.spage=735&rft.isbn=&rft.btitle=&rft.title=European+Journal+of+Clinical+Microbiology+%26+Infectious+Diseases&rft.issn=09349723&rft_id=info:doi/10.1007%2Fs10096-012-1798-0 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-06-01 N1 - Number of references - 27 N1 - Last updated - 2013-06-28 N1 - SubjectsTermNotLitGenreText - Rifampin; Drug resistance; biochips; Microscopy; Tuberculosis; Sputum; Drugs; Media (culture); Isoniazid; Mycobacterium tuberculosis DO - http://dx.doi.org/10.1007/s10096-012-1798-0 ER - TY - JOUR T1 - The effect of multiple primary rules on population-based cancer survival AN - 1356928709; 18007040 AB - Purpose: Different rules for registering multiple primary (MP) cancers are used by cancer registries throughout the world, making international data comparisons difficult. This study evaluates the effect of Surveillance, Epidemiology, and End Results (SEER) and International Association of Cancer Registries (IACR) MP rules on population-based cancer survival estimates. Methods: Data from five US states and six metropolitan area cancer registries participating in the SEER Program were used to estimate age-standardized relative survival (RS%) for first cancers-only and all first cancers matching the selection criteria according to SEER and IACR MP rules for all cancer sites combined and for the top 25 cancer site groups among men and women. Results: During 1995-2008, the percentage of MP cancers (all sites, both sexes) increased 25.4 % by using SEER rules (from 14.6 to 18.4 %) and 20.1 % by using IACR rules (from 13.2 to 15.8 %). More MP cancers were registered among females than among males, and SEER rules registered more MP cancers than IACR rules (15.8 vs. 14.4 % among males; 17.2 vs. 14.5 % among females). The top 3 cancer sites with the largest differences were melanoma (5.8 %), urinary bladder (3.5 %), and kidney and renal pelvis (2.9 %) among males, and breast (5.9 %), melanoma (3.9 %), and urinary bladder (3.4 %) among females. Five-year survival estimates (all sites combined) restricted to first primary cancers-only were higher than estimates by using first site-specific primaries (SEER or IACR rules), and for 11 of 21 sites among males and 11 of 23 sites among females. SEER estimates are comparable to IACR estimates for all site-specific cancers and marginally higher for all sites combined among females (RS 62.28 vs. 61.96 %). Conclusion: Survival after diagnosis has improved for many leading cancers. However, cancer patients remain at risk of subsequent cancers. Survival estimates based on first cancers-only exclude a large and increasing number of MP cancers. To produce clinically and epidemiologically relevant and less biased cancer survival estimates, data on all cancers should be included in the analysis. The multiple primary rules (SEER or IACR) used to identify primary cancers do not affect survival estimates if all first cancers matching the selection criteria are used to produce site-specific survival estimates. JF - Cancer Causes & Control AU - Weir, Hannah K AU - Johnson, Christopher J AU - Thompson, Trevor D AD - Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Hwy. MS-K55, Atlanta, GA, 30341, USA, hbw4@cdc.gov Y1 - 2013/06// PY - 2013 DA - Jun 2013 SP - 1231 EP - 1242 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 24 IS - 6 SN - 0957-5243, 0957-5243 KW - Risk Abstracts KW - Renal KW - Urinary bladder KW - Kidney KW - Survival KW - Cancer KW - Metropolitan areas KW - Melanoma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1356928709?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cancer+Causes+%26+Control&rft.atitle=The+effect+of+multiple+primary+rules+on+population-based+cancer+survival&rft.au=Weir%2C+Hannah+K%3BJohnson%2C+Christopher+J%3BThompson%2C+Trevor+D&rft.aulast=Weir&rft.aufirst=Hannah&rft.date=2013-06-01&rft.volume=24&rft.issue=6&rft.spage=1231&rft.isbn=&rft.btitle=&rft.title=Cancer+Causes+%26+Control&rft.issn=09575243&rft_id=info:doi/10.1007%2Fs10552-013-0203-3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-05-01 N1 - Number of references - 34 N1 - Last updated - 2013-06-14 N1 - SubjectsTermNotLitGenreText - Renal; Urinary bladder; Kidney; Survival; Metropolitan areas; Cancer; Melanoma DO - http://dx.doi.org/10.1007/s10552-013-0203-3 ER - TY - JOUR T1 - Use of expedited partner therapy among chlamydia cases diagnosed at an urban Indian health centre, Arizona AN - 1712569614; PQ0001965643 AB - Chlamydia cases diagnosed in the women's clinic were more likely to receive expedited partner therapy (EPT) and to be re-tested as compared with urgent and emergent care settings. Fewer re-infections occurred among patients who received EPT. Disproportionate rates of chlamydia occur among American Indian (Al) populations. To describe use of EPT among chlamydia cases diagnosed at an urban Indian Health Service (IHS) facility in Arizona, health records were used to extract confirmed cases of chlamydia diagnosed between January 2009 and August 2011. Medical records of 492 patients diagnosed with chlamydia were reviewed. Among the 472 cases who received treatment, 246 (52%) received EPT. Receipt of EPT was significantly associated with being female (odds ratio (OR) 2.1, 1.03-4.4, P < 0.001) and receipt of care in the women's clinic (OR 9.9, 95% CI 6.0-16.2) or in a primary care clinic (OR 2.4, 95% CI 1.1-5.1). Compared with those receiving care in the women's clinic, the odds of receipt of EPT were significantly less in those attending the urgent/express care clinic (OR 0.1, 95% CI 0.06-0.2), and the emergency department (OR 0.1, 95% CI 0.05-0.2). Among treated patients who underwent re-testing (N = 323, 68% total treated) re-infection was less common among those that received EPT (13% versus 27%; OR 0.5, 95% CI 0.3-0.9). In this IHS facility, EPT was protective in preventing chlamydia re-infection. Opportunities to expand the use of EPT were identified in urgent and emergent care settings. JF - International Journal of STD & AIDS AU - Taylor, M M AU - Reilley, B AU - Yellowman, M AU - Anderson, L AU - de Ravello, L AU - Tulloch, S AD - Centers for Disease Control and Prevention, Division of STD Prevention, Atlanta, GA, MDT7@CDC.GOV Y1 - 2013/05// PY - 2013 DA - May 2013 SP - 371 EP - 374 PB - Sage Publications, Inc., 2455 Teller Road Thousand Oaks CA 91320 United States VL - 24 IS - 5 SN - 0956-4624, 0956-4624 KW - Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts KW - chlamydia KW - sexually transmitted infection KW - STD KW - expedited partner therapy (EPT) KW - women's health KW - screening KW - treatment KW - patient delivered partner therapy KW - American Indian/Alaska Native KW - medical records KW - Chlamydia KW - V 22360:AIDS and HIV KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1712569614?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+STD+%26+AIDS&rft.atitle=Use+of+expedited+partner+therapy+among+chlamydia+cases+diagnosed+at+an+urban+Indian+health+centre%2C+Arizona&rft.au=Taylor%2C+M+M%3BReilley%2C+B%3BYellowman%2C+M%3BAnderson%2C+L%3Bde+Ravello%2C+L%3BTulloch%2C+S&rft.aulast=Taylor&rft.aufirst=M&rft.date=2013-05-01&rft.volume=24&rft.issue=5&rft.spage=371&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+STD+%26+AIDS&rft.issn=09564624&rft_id=info:doi/10.1177%2F0956462412472825 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-09-01 N1 - Last updated - 2015-11-16 N1 - SubjectsTermNotLitGenreText - medical records; Chlamydia DO - http://dx.doi.org/10.1177/0956462412472825 ER - TY - JOUR T1 - Molecular Characterization of Streptococcus pneumoniae Serotype 12F Isolates Associated with Rural Community Outbreaks in Alaska AN - 1448224356; 18643030 AB - Outbreaks of invasive pneumococcal disease (IPD) caused by Streptococcus pneumoniae serotype 12F were observed in two neighboring regions of rural Alaska in 2003 to 2006 and 2006 to 2008. IPD surveillance data from 1986 to 2009 and carriage survey data from 1998 to 2004 and 2008 to 2009 were reviewed to identify patterns of serotype 12F transmission. Pulsed-field gel electrophoresis was performed on all available isolates, and selected isolates were characterized by additional genetic subtyping methods. Serotype 12F IPD occurred in two waves in Alaska between 1986 and 2008. While cases of disease occurred nearly every year in Anchorage, in rural regions, 12F IPD occurred with rates 10- to 20-fold higher than those in Anchorage, often with many years between disease peaks and generally caused by a single predominant genetic clone. Carriage occurred predominantly in adults, except early in the rural outbreaks, when most carriage was in persons <18 years old. In rural regions, carriage of 12F disappeared completely after outbreaks. Different 12F clones appear to have been introduced episodically into rural populations, spread widely in young, immunologically naive populations (leading to outbreaks of IPD lasting 1 to 3 years), and then disappeared rapidly from the population. Larger population centers might have been the reservoir for these clones. This epidemiologic pattern is consistent with a highly virulent, but immunogenic, form of pneumococcus. JF - Journal of Clinical Microbiology AU - Zulz, Tammy AU - Wenger, Jay D AU - Rudolph, Karen AU - Robinson, D Ashley AU - Rakov, Alexey V AU - Bruden, Dana AU - Singleton, Rosalyn J AU - Bruce, Michael G AU - Hennessy, Thomas W Y1 - 2013/05// PY - 2013 DA - May 2013 SP - 1402 EP - 1407 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 51 IS - 5 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts KW - USA, Alaska KW - Electrophoresis KW - Serotypes KW - Data processing KW - Rural populations KW - Disease transmission KW - Streptococcus pneumoniae KW - Immunogenicity KW - Reviews KW - Pulsed-field gel electrophoresis KW - Waves KW - Outbreaks KW - Reservoirs KW - USA, Alaska, Anchorage KW - Rural areas KW - J 02310:Genetics & Taxonomy KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1448224356?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Molecular+Characterization+of+Streptococcus+pneumoniae+Serotype+12F+Isolates+Associated+with+Rural+Community+Outbreaks+in+Alaska&rft.au=Zulz%2C+Tammy%3BWenger%2C+Jay+D%3BRudolph%2C+Karen%3BRobinson%2C+D+Ashley%3BRakov%2C+Alexey+V%3BBruden%2C+Dana%3BSingleton%2C+Rosalyn+J%3BBruce%2C+Michael+G%3BHennessy%2C+Thomas+W&rft.aulast=Zulz&rft.aufirst=Tammy&rft.date=2013-05-01&rft.volume=51&rft.issue=5&rft.spage=1402&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.02880-12 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-10-01 N1 - Number of references - 30 N1 - Last updated - 2016-07-20 N1 - SubjectsTermNotLitGenreText - Data processing; Serotypes; Immunogenicity; Reviews; Pulsed-field gel electrophoresis; Rural populations; Waves; Disease transmission; Electrophoresis; Outbreaks; Reservoirs; Rural areas; Streptococcus pneumoniae; USA, Alaska; USA, Alaska, Anchorage DO - http://dx.doi.org/10.1128/JCM.02880-12 ER - TY - JOUR T1 - Detection of Fungal DNA in Human Body Fluids and Tissues during a Multistate Outbreak of Fungal Meningitis and Other Infections AN - 1443379335; 18642485 AB - Exserohilum rostratum was the major cause of an outbreak of fungal infections linked to injections of contaminated methylprednisolone acetate. Because almost 14,000 persons were exposed to product that was possibly contaminated with multiple fungal pathogens, there was unprecedented need for a rapid throughput diagnostic test that could detect both E. rostratum and other unusual agents of fungal infection. Here we report development of a novel PCR test that allowed for rapid and specific detection of fungal DNA in cerebrospinal fluid (CSF), other body fluids and tissues of infected individuals. The test relied on direct purification of free-circulating fungal DNA from fluids and subsequent PCR amplification and sequencing. Using this method, we detected Exserohilum rostratum DNA in 123 samples from 114 case-patients (28% of 413 case-patients for whom 627 samples were available), and Cladosporium DNA in one sample from one case-patient. PCR with novel Exserohilum-specific ITS-2 region primers detected 25 case-patients with samples that were negative using broad-range ITS primers. Compared to fungal culture, this molecular test was more sensitive: of 139 case-patients with an identical specimen tested by culture and PCR, E. rostratum was recovered in culture from 19 (14%), but detected by PCR in 41 (29%), showing a diagnostic sensitivity of 29% for PCR compared to 14% for culture in this patient group. The ability to rapidly confirm the etiologic role of E. rostratum in these infections provided an important contribution in the public health response to this outbreak. JF - Eukaryotic Cell AU - Gade, Lalitha AU - Scheel, Christina M AU - Pham, Cau D AU - Lindsley, Mark D AU - Iqbal, Naureen AU - Cleveland, Angela Ahlquist AU - Whitney, Anne M AU - Lockhart, Shawn R AU - Brandt, Mary E AU - Litvintseva, Anastasia P AD - National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, frq8@cdc.gov. Y1 - 2013/05// PY - 2013 DA - May 2013 SP - 677 EP - 683 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 12 IS - 5 SN - 1535-9786, 1535-9786 KW - Biochemistry Abstracts 2: Nucleic Acids; Health & Safety Science Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Acetic acid KW - DNA KW - Polymerase chain reaction KW - Cladosporium KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - N:14810 KW - K:03400 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1443379335?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Eukaryotic+Cell&rft.atitle=Detection+of+Fungal+DNA+in+Human+Body+Fluids+and+Tissues+during+a+Multistate+Outbreak+of+Fungal+Meningitis+and+Other+Infections&rft.au=Gade%2C+Lalitha%3BScheel%2C+Christina+M%3BPham%2C+Cau+D%3BLindsley%2C+Mark+D%3BIqbal%2C+Naureen%3BCleveland%2C+Angela+Ahlquist%3BWhitney%2C+Anne+M%3BLockhart%2C+Shawn+R%3BBrandt%2C+Mary+E%3BLitvintseva%2C+Anastasia+P&rft.aulast=Gade&rft.aufirst=Lalitha&rft.date=2013-05-01&rft.volume=12&rft.issue=5&rft.spage=677&rft.isbn=&rft.btitle=&rft.title=Eukaryotic+Cell&rft.issn=15359786&rft_id=info:doi/10.1128%2FEC.00046-13 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-10-01 N1 - Number of references - 1 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Polymerase chain reaction; DNA; Cladosporium DO - http://dx.doi.org/10.1128/EC.00046-13 ER - TY - JOUR T1 - Multiple Independent Emergences of Type 2 Vaccine-Derived Polioviruses during a Large Outbreak in Northern Nigeria AN - 1443373168; 18643205 AB - Since 2005, a large poliomyelitis outbreak associated with type 2 circulating vaccine-derived poliovirus (cVDPV2) has occurred in northern Nigeria, where immunization coverage with trivalent oral poliovirus vaccine (tOPV) has been low. Phylogenetic analysis of P1/capsid region sequences of isolates from each of the 403 cases reported in 2005 to 2011 resolved the outbreak into 23 independent type 2 vaccine-derived poliovirus (VDPV2) emergences, at least 7 of which established circulating lineage groups. Virus from one emergence (lineage group 2005-8; 361 isolates) was estimated to have circulated for over 6 years. The population of the major cVDPV2 lineage group expanded rapidly in early 2009, fell sharply after two tOPV rounds in mid-2009, and gradually expanded again through 2011. The two major determinants of attenuation of the Sabin 2 oral poliovirus vaccine strain (A481 in the 5'-untranslated region [5'-UTR] and VP1-Ile143) had been replaced in all VDPV2 isolates; most A481 5'-UTR replacements occurred by recombination with other enteroviruses. cVDPV2 isolates representing different lineage groups had biological properties indistinguishable from those of wild polioviruses, including efficient growth in neuron-derived HEK293 cells, the capacity to cause paralytic disease in both humans and PVR-Tg21 transgenic mice, loss of the temperature-sensitive phenotype, and the capacity for sustained person-to-person transmission. We estimate from the poliomyelitis case count and the paralytic case-to-infection ratio for type 2 wild poliovirus infections that similar to 700,000 cVDPV2 infections have occurred during the outbreak. The detection of multiple concurrent cVDPV2 outbreaks in northern Nigeria highlights the risks of cVDPV emergence accompanying tOPV use at low rates of coverage in developing countries. JF - Journal of Virology AU - Burns, Cara C AU - Shaw, Jing AU - Jorba, Jaume AU - Bukbuk, David AU - Adu, Festus AU - Gumede, Nicksy AU - Pate, Muhammed Ali AU - Abanida, Emmanuel Ade AU - Gasasira, Alex AU - Iber, Jane AD - Centers for Disease Control and Prevention, Atlanta, Georgia, USA, CBurns@cdc.gov. Y1 - 2013/05// PY - 2013 DA - May 2013 SP - 4907 EP - 4922 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 87 IS - 9 SN - 0022-538X, 0022-538X KW - Immunology Abstracts; Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - 5' Untranslated Regions KW - Nigeria KW - Poliovirus KW - Vaccines KW - V:22310 KW - F:06910 KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1443373168?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Virology&rft.atitle=Multiple+Independent+Emergences+of+Type+2+Vaccine-Derived+Polioviruses+during+a+Large+Outbreak+in+Northern+Nigeria&rft.au=Burns%2C+Cara+C%3BShaw%2C+Jing%3BJorba%2C+Jaume%3BBukbuk%2C+David%3BAdu%2C+Festus%3BGumede%2C+Nicksy%3BPate%2C+Muhammed+Ali%3BAbanida%2C+Emmanuel+Ade%3BGasasira%2C+Alex%3BIber%2C+Jane&rft.aulast=Burns&rft.aufirst=Cara&rft.date=2013-05-01&rft.volume=87&rft.issue=9&rft.spage=4907&rft.isbn=&rft.btitle=&rft.title=Journal+of+Virology&rft.issn=0022538X&rft_id=info:doi/10.1128%2FJVI.02954-12 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-10-01 N1 - Number of references - 1 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Vaccines; Poliovirus; Nigeria DO - http://dx.doi.org/10.1128/JVI.02954-12 ER - TY - JOUR T1 - Paediatric malaria in Greece in the era of global population mobility AN - 1430858060; 18286835 AB - We reviewed the medical records of children admitted because of malaria to four tertiary-care hospitals in Greece during 1972-2002. A total of 21 cases were found, including 20 (95.2%) diagnosed during 2003-2012. Sixteen (76.2%) children had been in a malaria-endemic country within a median of 50 days before the onset of their symptoms. Main causes of travel were immigration to Greece and to visit friends and relatives (VFRs). A considerable epidemiological shift of paediatric malaria occurred in Greece during the past decade, which is attributed almost exclusively to the increase of immigrants and travellers VFRs. JF - Travel Medicine and Infectious Disease AU - Maltezou, Helena C AU - Tsolia, Maria AU - Polymerou, Ioannis AU - Theodoridou, Maria AD - Department for Interventions in Health-Care Facilities, Hellenic Center for Disease Control and Prevention, 3-5 Agrafon Street, Athens, Greece Y1 - 2013/05// PY - 2013 DA - May 2013 SP - 178 EP - 180 PB - Elsevier VL - 11 IS - 3 SN - 1477-8939, 1477-8939 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Health & Safety Science Abstracts KW - Malaria KW - Children KW - Travel KW - Immigrants KW - Greece KW - Symptoms KW - Human diseases KW - Mobility KW - Population dynamics KW - Public health KW - Infectious diseases KW - Immigration KW - Pediatrics KW - medical records KW - Travellers KW - Reviews KW - Hospitals KW - K 03400:Human Diseases KW - Q1 08484:Species interactions: parasites and diseases KW - H 12000:Epidemiology and Public Health KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1430858060?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Travel+Medicine+and+Infectious+Disease&rft.atitle=Paediatric+malaria+in+Greece+in+the+era+of+global+population+mobility&rft.au=Maltezou%2C+Helena+C%3BTsolia%2C+Maria%3BPolymerou%2C+Ioannis%3BTheodoridou%2C+Maria&rft.aulast=Maltezou&rft.aufirst=Helena&rft.date=2013-05-01&rft.volume=11&rft.issue=3&rft.spage=178&rft.isbn=&rft.btitle=&rft.title=Travel+Medicine+and+Infectious+Disease&rft.issn=14778939&rft_id=info:doi/10.1016%2Fj.tmaid.2013.02.007 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-09-01 N1 - Last updated - 2015-10-28 N1 - SubjectsTermNotLitGenreText - Symptoms; Human diseases; Infectious diseases; Malaria; Public health; Travel; Immigration; Mobility; medical records; Pediatrics; Reviews; Immigrants; Travellers; Children; Hospitals; Population dynamics; Greece DO - http://dx.doi.org/10.1016/j.tmaid.2013.02.007 ER - TY - JOUR T1 - OUTBREAK OF NOROVIRUS GASTROENTERITIS INFECTION, THAILAND AN - 1412552087; 18229512 AB - Norovirus is a leading cause of gastrointestinal illness worldwide. We investigated an outbreak of gastrointestinal illness in Pattaya, Thailand, among participants of a course. We asked participants and family members to complete a questionnaire asking about symptoms, meals eaten, and foods consumed during the course. We collected stool samples from persons reporting illness and analyzed specimens for several viruses and enteropathogenic bacteria. We defined a case as a person having one or more episodes of diarrhea, with onset between 30 August and 1 September 2010, in a participant or family member who attended the course. Of 56 people who attended, 95% completed the questionnaire: nine met the case definition (attack rate, 17%). Common symptoms included abdominal cramps, nausea, fatigue, headache, and vomiting. Food items with elevated risk ratios included: crispy fish maw, dried squid, and cashew nut salad [risk ratio (RR) 5.1; 95% confidence interval (CI) 0.7-37]; assorted salad bar with dressing (RR 3.0; 95% CI 0.9-11); and seafood kebab (RR 5.8; 95% CI 0.8-43). Among ill persons, four (44%) provided stool samples and two (50%) were positive for norovirus. Our data suggest a foodborne outbreak of norovirus. Increased use of norovirus diagnostics as well as measures to prevent transmission may help identify additional outbreaks and improve control measures to limit the spread of outbreaks. JF - Southeast Asian Journal of Tropical Medicine & Public Health AU - McCarthy, K S AU - Guntapong, R AU - Thattiyaphong, A AU - Wangroongsarb, P AU - Hall, A J AU - Olsen, S J AU - Holtz, TH AD - Thailand MOPH - US CDC Collaboration, DDC7 Building, 4th Floor, Ministry of Public Health, Nonthaburi, 11000, Thailand, tkh3@cdc.gov Y1 - 2013/05// PY - 2013 DA - May 2013 SP - 409 EP - 416 VL - 44 IS - 3 SN - 0125-1562, 0125-1562 KW - Virology & AIDS Abstracts; ASFA 1: Biological Sciences & Living Resources; Risk Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts KW - Symptoms KW - Dressings KW - Vomiting KW - Thailand KW - Food KW - Dressing KW - Viruses KW - Infection KW - Anacardium KW - Food-borne diseases KW - Disease transmission KW - Public health KW - Headache KW - Nausea KW - Seafood KW - ISEW, Thailand KW - Feces KW - Inventories KW - Fatigue KW - Data processing KW - Diarrhea KW - Norovirus KW - Food contamination KW - Fish KW - Outbreaks KW - Gastroenteritis KW - Q1 08485:Species interactions: pests and control KW - H 12000:Epidemiology and Public Health KW - R2 23060:Medical and environmental health KW - Q5 08524:Public health, medicines, dangerous organisms KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1412552087?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Southeast+Asian+Journal+of+Tropical+Medicine+%26+Public+Health&rft.atitle=OUTBREAK+OF+NOROVIRUS+GASTROENTERITIS+INFECTION%2C+THAILAND&rft.au=McCarthy%2C+K+S%3BGuntapong%2C+R%3BThattiyaphong%2C+A%3BWangroongsarb%2C+P%3BHall%2C+A+J%3BOlsen%2C+S+J%3BHoltz%2C+TH&rft.aulast=McCarthy&rft.aufirst=K&rft.date=2013-05-01&rft.volume=44&rft.issue=3&rft.spage=409&rft.isbn=&rft.btitle=&rft.title=Southeast+Asian+Journal+of+Tropical+Medicine+%26+Public+Health&rft.issn=01251562&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-07-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Symptoms; Dressing; Viruses; Seafood; Public health; Inventories; Diarrhea; Vomiting; Data processing; Fatigue; Dressings; Food; Infection; Disease transmission; Headache; Nausea; Feces; Gastroenteritis; Fish; Outbreaks; Food contamination; Food-borne diseases; Norovirus; Anacardium; Thailand; ISEW, Thailand ER - TY - JOUR T1 - Modelling fortification of corn masa flour with folic acid and the potential impact on Mexican-American women with lower acculturation AN - 1372057699; 18146752 AB - Hispanics with lower acculturation may be at higher risk for neural tube defects compared with those with higher acculturation due to lower total folic acid intake or other undetermined factors. Modelling has indicated that fortification of corn masa flour with folic acid could selectively target Mexican Americans more than other race/ethnicities. We assessed whether fortification of corn masa flour with folic acid could selectively increase folic acid intake among Mexican-American women with lower acculturation, as indicated by specific factors (language preference, country of origin, time living in the USA). We used dietary intake and dietary supplement data from the National Health and Nutrition Examination Survey 2001-2008, to estimate the amount of additional total folic acid that could be consumed if products considered to contain corn masa flour were fortified at 140 mu g of folic acid per 100 g of corn masa flour. USA. Non-pregnant women aged 15-44 years (n 5369). Mexican-American women who reported speaking Spanish had a relative percentage change in usual daily total folic acid intake of 30.5 (95 % CI 27.8, 33.4) %, compared with 8.3 (95 % CI 7.3, 9.4) % for Mexican-American women who reported speaking English. We observed similar results for other acculturation factors. An increase of 6.0 percentage points in the number of Mexican-American women who would achieve the recommended intake of greater than or equal to 400 mu g folic acid/d occurred with fortification of corn masa flour; compared with increases of 1.1 percentage points for non-Hispanic whites and 1.3 percentage points for non-Hispanic blacks. An even greater percentage point increase was observed among Mexican-American women who reported speaking Spanish (8.2). Fortification of corn masa flour could selectively increase total folic acid intake among Mexican-American women, especially targeting Mexican-American women with lower acculturation, and result in a decrease in the number of pregnancies affected by neural tube defects. JF - Public Health Nutrition AU - Hamner, Heather C AU - Tinker, Sarah C AU - Flores, Alina L AU - Mulinare, Joe AU - Weakland, Aliki P AU - Dowling, Nicole F AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention (CDC), 1600 Clifton Road NE, MS E-86, Atlanta, GA 30033, USA, hfc2@cdc.gov Y1 - 2013/05// PY - 2013 DA - May 2013 SP - 912 EP - 921 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 16 IS - 5 SN - 1368-9800, 1368-9800 KW - Risk Abstracts KW - Corn KW - USA KW - Folic acid KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1372057699?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Public+Health+Nutrition&rft.atitle=Modelling+fortification+of+corn+masa+flour+with+folic+acid+and+the+potential+impact+on+Mexican-American+women+with+lower+acculturation&rft.au=Hamner%2C+Heather+C%3BTinker%2C+Sarah+C%3BFlores%2C+Alina+L%3BMulinare%2C+Joe%3BWeakland%2C+Aliki+P%3BDowling%2C+Nicole+F&rft.aulast=Hamner&rft.aufirst=Heather&rft.date=2013-05-01&rft.volume=16&rft.issue=5&rft.spage=912&rft.isbn=&rft.btitle=&rft.title=Public+Health+Nutrition&rft.issn=13689800&rft_id=info:doi/10.1017%2FS1368980012004582 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-06-01 N1 - Number of references - 1 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Folic acid; USA DO - http://dx.doi.org/10.1017/S1368980012004582 ER - TY - JOUR T1 - Determination of 16 typical chlorinated persistent organic pollutants in groundwater by gas chromatography-high resolution mass spectrometry AN - 1832652715; 740929-21 AB - 9 kinds of organochlorine pesticides(alpha -HCH, beta -HCH, gamma -HCH, delta -HCH, hexachlorobenzene, p,p?DDE, p,p?DDD, o, p?DDT and p,p?DDT) and 7 kinds of polychlorinated biphenyls (PCB 28, PCB 52, PCB 101, PCB 118 , PCB 138, PCB 153 and PCB 180) were the target compounds of national ground water quality investigation. Until now, the low sensitivity of Gas Chromatography with Electron Capture Detector(GC-ECD) and Gas Chromatography-Mass Spectrometry/Selected Ion Monitoring(GC-MS/SIM) technique have been applied to monitor the quality of ground water, however, these analysis methods are unable to monitor trace and ultra-trace the persistent organic pollutants targeted in ground water. In this paper, a high sensitivity analysis method of the target compounds in groundwater by solid phase disk extraction coupled with Gas Chromatography-High Resolution Mass Spectrometry(GC-HRMS) is described. The detection limits for the target compounds were 0.10-0.20 ng/L, the recovery with standards were 61.9%-93.3% and RSD(n=5) were 2.41%-20.0%. The method was applied for detection of the target compounds in groundwater using samples from two different areas of China. The analytical results show that no PCBs were detected in any of the samples, but two water samples may be contaminated with a new gamma -hexachlorocyclohexane emission source according to the detection of alpha -hexachlorocyclohexane and gamma -hexachlorocyclohexane and their residual concentration ratios. JF - Yankuang Ceshi = Rock and Mineral Analysis AU - Song, Shuling AU - Guo, Xiaochen AU - Hu, Xiaojian AU - Li, Hongzhi Y1 - 2013/04// PY - 2013 DA - April 2013 SP - 319 EP - 324 PB - Dizhi Chubanshe, Beijing VL - 32 IS - 2 SN - 0254-5357, 0254-5357 KW - chlorinated hydrocarbons KW - chromatography KW - pollutants KW - pollution KW - organochlorine pesticides KW - mass spectroscopy KW - ground water KW - gas chromatography KW - sample preparation KW - organic compounds KW - halogenated hydrocarbons KW - pesticides KW - water pollution KW - spectroscopy KW - geochemistry KW - 22:Environmental geology KW - 02A:General geochemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1832652715?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefinprocess&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Yankuang+Ceshi+%3D+Rock+and+Mineral+Analysis&rft.atitle=Determination+of+16+typical+chlorinated+persistent+organic+pollutants+in+groundwater+by+gas+chromatography-high+resolution+mass+spectrometry&rft.au=Song%2C+Shuling%3BGuo%2C+Xiaochen%3BHu%2C+Xiaojian%3BLi%2C+Hongzhi&rft.aulast=Song&rft.aufirst=Shuling&rft.date=2013-04-01&rft.volume=32&rft.issue=2&rft.spage=319&rft.isbn=&rft.btitle=&rft.title=Yankuang+Ceshi+%3D+Rock+and+Mineral+Analysis&rft.issn=02545357&rft_id=info:doi/ LA - Chinese DB - GeoRef N1 - Copyright - GeoRef in Process, Copyright 2017, American Geosciences Institute. After editing and indexing, this record will be added to Georef. N1 - Number of references - 25 N1 - Document feature - illus. incl. 2 tables N1 - Last updated - 2017-01-24 N1 - SubjectsTermNotLitGenreText - chlorinated hydrocarbons; chromatography; gas chromatography; geochemistry; ground water; halogenated hydrocarbons; mass spectroscopy; organic compounds; organochlorine pesticides; pesticides; pollutants; pollution; sample preparation; spectroscopy; water pollution ER - TY - JOUR T1 - Short Report: Origin of the St. Elizabeth Strain of Plasmodium vivax AN - 1647004891; 21172050 AB - The St. Elizabeth strain of Plasmodium vivax originated in the South Carolina State Hospital instead of the St. Elizabeth Hospital in Washington, DC. JF - American Journal of Tropical Medicine and Hygiene AU - Collins, William AD - Center for Disease Control and Prevention, Division of Parasitic Diseases, Atlanta, Georgia, wec1@cdc.gov Y1 - 2013/04// PY - 2013 DA - April 2013 SP - 726 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 United States VL - 88 IS - 4 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts C: Algology, Mycology & Protozoology; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Health & Safety Science Abstracts KW - ANW, USA, South Carolina KW - Plasmodium vivax KW - Hygiene KW - USA, Washington, D.C. KW - Hospitals KW - K 03400:Human Diseases KW - Q1 08484:Species interactions: parasites and diseases KW - H 13000:Medical Safety KW - J 02400:Human Diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1647004891?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Short+Report%3A+Origin+of+the+St.+Elizabeth+Strain+of+Plasmodium+vivax&rft.au=Collins%2C+William&rft.aulast=Collins&rft.aufirst=William&rft.date=2013-04-01&rft.volume=88&rft.issue=4&rft.spage=726&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.12-0351 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2016-10-26 N1 - SubjectsTermNotLitGenreText - Hygiene; Hospitals; Plasmodium vivax; ANW, USA, South Carolina; USA, Washington, D.C. DO - http://dx.doi.org/10.4269/ajtmh.12-0351 ER - TY - JOUR T1 - Persistence of the 2009 Pandemic Influenza A (H1N1) Virus on N95 Respirators AN - 1443376471; 18642682 AB - In the United States, the 2009 pandemic influenza A (H1N1) virus (pH1N1) infected almost 20% of the population and caused >200,000 hospitalizations and >10,000 deaths from April 2009 to April 2010. On 24 April 2009, the CDC posted interim guidance on infection control measures in health care settings explicitly for pH1N1 and recommended using filtering face respirators (FFRs) when in close contact with a suspected- or confirmed-to-be-infected individual, particularly when performing aerosol-generating procedures. The persistence and infectivity of pH1N1 were evaluated on FFRs, specifically N95 respirators, under various conditions of absolute humidity (AH) (4.1 105 mPa, 6.5 105 mPa, and 14.6 105 mPa), sample matrices (2% fetal bovine serum [FBS], 5 mg/ml mucin, and viral medium), and times (4, 12, 24, 48, 72, and 144 h). pH1N1 was distributed onto N95 coupons (3.8 to 4.2 cm2) and extracted by a vortex-centrifugation-filtration process, and the ability of the remaining virus to replicate was quantified using an enzyme-linked immunosorbent assay (ELISA) to determine the log10 concentration of the infectious virus per coupon. Overall, pH1N1 remained infectious for 6 days, with an approximately 1-log10 loss of virus concentrations over this time period. Time and AH both affected virus survival. We found significantly higher (P less than or equal to 0.01) reductions in virus concentrations at time points beyond 24 to 72 h (-0.52-log10 reduction) and 144 h (-0.74) at AHs of 6.5 105 mPa (-0.53) and 14.6 105 mPa (-0.47). This research supports discarding respirators after close contact with a person with suspected or confirmed influenza infection due to the virus's demonstrated ability to persist and remain infectious. JF - Applied and Environmental Microbiology AU - Coulliette, A D AU - Perry, K A AU - Edwards, J R AU - Noble-Wang, J A Y1 - 2013/04// PY - 2013 DA - Apr 2013 SP - 2148 EP - 2155 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 79 IS - 7 SN - 0099-2240, 0099-2240 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Absolute humidity KW - USA KW - Respirators KW - V:22400 KW - A:01340 KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1443376471?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Persistence+of+the+2009+Pandemic+Influenza+A+%28H1N1%29+Virus+on+N95+Respirators&rft.au=Coulliette%2C+A+D%3BPerry%2C+K+A%3BEdwards%2C+J+R%3BNoble-Wang%2C+J+A&rft.aulast=Coulliette&rft.aufirst=A&rft.date=2013-04-01&rft.volume=79&rft.issue=7&rft.spage=2148&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/10.1128%2FAEM.03850-12 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-10-01 N1 - Number of references - 1 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Respirators; USA DO - http://dx.doi.org/10.1128/AEM.03850-12 ER - TY - JOUR T1 - Disparities Between Black and White Children in Hospitalizations Associated With Acute Respiratory Illness and Laboratory-confirmed Influenza and Respiratory Syncytial Virus in 3 US Counties-2002-2009 AN - 1348487693; 17910802 AB - Few US studies have assessed racial disparities in viral respiratory hospitalizations among children. This study enrolled black and white children under 5 years of age who were hospitalized for acute respiratory illness (ARI) in 3 US counties during October-May 2002-2009. Population-based rates of hospitalization were calculated by race for ARI and laboratory-confirmed influenza and respiratory syncytial virus (RSV), using US Census denominators. Relative rates of hospitalization between racial groups were estimated. Of 1,415 hospitalized black children and 1,824 hospitalized white children with ARI enrolled in the study, 108 (8%) black children and 111 (6%) white children had influenza and 230 (19%) black children and 441 (29%) white children had RSV. Hospitalization rates were higher among black children than among white children for ARI (relative rate (RR) = 1.7, 95% confidence interval (CI): 1.6, 1.8) and influenza (RR = 2.1, 95% CI: 1.6, 2.9). For RSV, rates were similar among black and white children under age 12 months but higher for black children aged 12 months or more (for ages 12-23 months, RR = 1.7, 95% CI: 1.1, 2.5; for ages 24-59 months, RR = 2.2, 95% CI: 1.3, 3.6). Black children versus white children were significantly more likely to have public insurance or no insurance (85% vs. 43%) and a history of asthma/wheezing (28% vs. 18%) but not more severe illness. The observed racial disparities require further study. JF - American Journal of Epidemiology AU - Iwane, Marika K AU - Chaves, Sandra S AU - Szilagyi, Peter G AU - Edwards, Kathryn M AU - Hall, Caroline B AU - Staat, Mary A AU - Brown, Cedric J AU - Griffin, Marie R AU - Weinberg, Geoffrey A AU - Poehling, Katherine A AU - Prill, Mila M AU - Williams, John V AU - Bridges, Carolyn B AD - Correspondence to Dr. Marika K. Iwane, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Mailstop A34, Atlanta, GA 30333., miwane@cdc.gov Y1 - 2013/04/01/ PY - 2013 DA - 2013 Apr 01 SP - 656 EP - 665 PB - Oxford University Press, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 177 IS - 7 SN - 0002-9262, 0002-9262 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Age KW - Respiratory syncytial virus KW - USA KW - Children KW - H 1000:Occupational Safety and Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1348487693?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Epidemiology&rft.atitle=Disparities+Between+Black+and+White+Children+in+Hospitalizations+Associated+With+Acute+Respiratory+Illness+and+Laboratory-confirmed+Influenza+and+Respiratory+Syncytial+Virus+in+3+US+Counties-2002-2009&rft.au=Iwane%2C+Marika+K%3BChaves%2C+Sandra+S%3BSzilagyi%2C+Peter+G%3BEdwards%2C+Kathryn+M%3BHall%2C+Caroline+B%3BStaat%2C+Mary+A%3BBrown%2C+Cedric+J%3BGriffin%2C+Marie+R%3BWeinberg%2C+Geoffrey+A%3BPoehling%2C+Katherine+A%3BPrill%2C+Mila+M%3BWilliams%2C+John+V%3BBridges%2C+Carolyn+B&rft.aulast=Iwane&rft.aufirst=Marika&rft.date=2013-04-01&rft.volume=177&rft.issue=7&rft.spage=656&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Epidemiology&rft.issn=00029262&rft_id=info:doi/10.1093%2Faje%2Fkws299 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-05-01 N1 - Last updated - 2014-03-10 N1 - SubjectsTermNotLitGenreText - Children; Respiratory syncytial virus; USA DO - http://dx.doi.org/10.1093/aje/kws299 ER - TY - JOUR T1 - A Systematic Qualitative Review of Risk and Protective Factors for Sexual Violence Perpetration AN - 1323800894; 17782625 AB - The current review summarized results of 191 published empirical studies that examined the risk and protective factors for sexual violence perpetration. Studies in the review examined factors for perpetration by and against adolescents and adults, by male and female perpetrators, and by those who offended against individuals of the same sex or opposite sex. Factors associated with child sexual abuse (CSA) perpetration were not included. In all, 2 societal and community factors, 23 relationship factors, and 42 individual-level factors were identified. Of these 67 factors, consistent significant support for their association with SV was found for 35, nonsignificant effects were found for 10, 7 factors had limited or sample-specific evidence that they were associated with SV but were in need of further study, and 15 demonstrated mixed results. The factors identified in the review underscore the need for comprehensive prevention programs that target multiple risk and protective factors as well as factors that occur across the social ecology. Moreover, we identified two domains of factors-the presence and acceptance of violence and unhealthy sexual behaviors, experiences, or attitudes-that had consistent significant associations with SV but are not typically addressed in prevention programs. Therefore, SV prevention may also benefit from learning from effective strategies in other areas of public health, namely sexual health and youth violence prevention. JF - Trauma, Violence & Abuse AU - Tharp, Andra Teten AU - DeGue, Sarah AU - Valle, Linda Anne AU - Brookmeyer, Kathryn A AU - Massetti, Greta M AU - Matjasko, Jennifer L AD - Centers for Disease Control and Prevention, Atlanta, GA, USA, atharp@cdc.gov Y1 - 2013/04// PY - 2013 DA - Apr 2013 SP - 133 EP - 167 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU United Kingdom VL - 14 IS - 2 SN - 1524-8380, 1524-8380 KW - Health & Safety Science Abstracts; Risk Abstracts KW - Adolescents KW - Child abuse KW - Prevention KW - Public health KW - Reviews KW - Sexual assault KW - Sexual behavior KW - Violence KW - H 11000:Diseases/Injuries/Trauma KW - R2 23050:Environment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1323800894?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Trauma%2C+Violence+%26+Abuse&rft.atitle=A+Systematic+Qualitative+Review+of+Risk+and+Protective+Factors+for+Sexual+Violence+Perpetration&rft.au=Tharp%2C+Andra+Teten%3BDeGue%2C+Sarah%3BValle%2C+Linda+Anne%3BBrookmeyer%2C+Kathryn+A%3BMassetti%2C+Greta+M%3BMatjasko%2C+Jennifer+L&rft.aulast=Tharp&rft.aufirst=Andra&rft.date=2013-04-01&rft.volume=14&rft.issue=2&rft.spage=133&rft.isbn=&rft.btitle=&rft.title=Trauma%2C+Violence+%26+Abuse&rft.issn=15248380&rft_id=info:doi/10.1177%2F1524838012470031 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-04-01 N1 - Number of references - 259 N1 - Last updated - 2013-05-06 N1 - SubjectsTermNotLitGenreText - Prevention; Reviews; Child abuse; Sexual assault; Sexual behavior; Violence; Adolescents; Public health DO - http://dx.doi.org/10.1177/1524838012470031 ER - TY - JOUR T1 - Passive multistate surveillance for neutropenia after use of cocaine or heroin possibly contaminated with levamisole. AN - 1319618007; 23374417 AB - To characterize the demographic, clinical, and epidemiologic features of levamisole-associated neutropenia in cocaine or heroin users. State health departments were recruited for participation when the Centers for Disease Control and Prevention (CDC) was notified of potential cases by a clinician, a health department official, or a poison center between October 15, 2009, and May 31, 2010. A case was defined as a person with an absolute neutrophil count less than 1,000 cells/μL (or a WBC count <2,000 cells/μL) and a self-reported history or laboratory confirmation of cocaine or heroin use. Health department officials abstracted data from medical charts, attempted a patient interview, and submitted data to CDC for descriptive analysis. Of the 46 potential cases reported from 6 states, half met eligibility criteria and had medical chart abstractions completed (n=23; 50%). Of these, close to half of the patients were interviewed (n=10; 43%). The average age was 44.4 years; just over half were men (n=12; 52%). The majority of patients presented to emergency departments (n=19; 83%). More than half presented with infectious illnesses (n=12; 52%), and nearly half reported active skin lesions (n=10; 44%). The majority of interview respondents used cocaine greater than 2 to 3 times a week (n=9; 90%), used cocaine more than 2 years (n=6; 60%), and preferred crack cocaine (n=6; 60%). All were unaware of exposure to levamisole through cocaine and of levamisole's inherent toxicity (n=10; 100%). Physicians should suspect levamisole exposure in patients using illicit drugs, cocaine in particular, who present with unexplained neutropenia. Most patients reported chronic cocaine use and were unaware of levamisole exposure. Cocaine use is more prevalent among men; however, our results identified a higher-than-expected proportion of female users with neutropenia, suggesting women may be at higher risk. Emergency physicians and practitioners are uniquely positioned to recognize these patients early during their hospital course, elucidate a history of cocaine or other drug exposure, and optimize the likelihood of confirming exposure by arranging for appropriate drug testing. Copyright © 2012. Published by Mosby, Inc. JF - Annals of emergency medicine AU - Vagi, Sara J AU - Sheikh, Sophia AU - Brackney, Monica AU - Smolinske, Susan AU - Warrick, Brandon AU - Reuter, Nicholas AU - Schier, Joshua G AD - Centers for Disease Control and Prevention. svagi@cdc.gov Y1 - 2013/04// PY - 2013 DA - April 2013 SP - 468 EP - 474 VL - 61 IS - 4 KW - Levamisole KW - 2880D3468G KW - Heroin KW - 70D95007SX KW - Cocaine KW - I5Y540LHVR KW - Abridged Index Medicus KW - Index Medicus KW - Heroin -- adverse effects KW - Humans KW - Adult KW - Interviews as Topic KW - Middle Aged KW - United States -- epidemiology KW - Cocaine -- adverse effects KW - Male KW - Female KW - Population Surveillance KW - Neutropenia -- epidemiology KW - Drug Contamination -- statistics & numerical data KW - Neutropenia -- chemically induced KW - Levamisole -- adverse effects KW - Heroin Dependence -- complications KW - Cocaine-Related Disorders -- complications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1319618007?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annals+of+emergency+medicine&rft.atitle=Passive+multistate+surveillance+for+neutropenia+after+use+of+cocaine+or+heroin+possibly+contaminated+with+levamisole.&rft.au=Vagi%2C+Sara+J%3BSheikh%2C+Sophia%3BBrackney%2C+Monica%3BSmolinske%2C+Susan%3BWarrick%2C+Brandon%3BReuter%2C+Nicholas%3BSchier%2C+Joshua+G&rft.aulast=Vagi&rft.aufirst=Sara&rft.date=2013-04-01&rft.volume=61&rft.issue=4&rft.spage=468&rft.isbn=&rft.btitle=&rft.title=Annals+of+emergency+medicine&rft.issn=1097-6760&rft_id=info:doi/10.1016%2Fj.annemergmed.2012.10.036 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2013-12-11 N1 - Date created - 2013-03-25 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.annemergmed.2012.10.036 ER - TY - JOUR T1 - A Cluster of Patients Infected With I221V Influenza B Virus Variants With Reduced Oseltamivir Susceptibility-North Carolina and South Carolina, 2010-2011 AN - 1642623576; 20900157 AB - Background. During 2010-2011, influenza B viruses with a novel neuraminidase substitution, denoted I221V (B/I221V), associated with reduced in vitro oseltamivir susceptibility were detected in North Carolina. Methods. We determined the prevalence of I221V among B viruses submitted to the Centers for Disease Control and Prevention for antiviral resistance surveillance, including all B viruses submitted to North Carolina and South Carolina state laboratories, during October 2010-September 2011. We conducted chart reviews and telephone interviews to characterize North Carolina and South Carolina patients with B/I221V vs wild-type B virus infection (B/WT). Results. We detected I221V in 45 (22%) of 209 B viruses from North Carolina and 8 (10%) of 82 B viruses from South Carolina. We detected I221V in 3 (0.3%) of 881 B viruses tested from 45 other states. B/I221V infection was not associated with differences in underlying conditions or illness severity, compared with B/WT infection. No patients with B/I221V infection received oseltamivir prior to specimen collection. Among patients who completed oseltamivir, those with B/I221V infection reported a longer duration until illness resolution (5 vs 3 days; P = .02). Conclusions. B/I221V cocirculated with B/WT in North Carolina and South Carolina during 2010-2011. I221V did not alter illness severity but may have reduced oseltamivir effectiveness. Thus, global surveillance for I221V is important. JF - Journal of Infectious Diseases AU - Garg, Shikha AU - Moore, Zack AU - Lee, Nicole AU - McKenna, John AU - Bishop, Amber AU - Fleischauer, Aaron AU - Springs, Chasisity B AU - Nguyen, Ha T AU - Sheu, Tiffany G AU - Sleeman, Katrina AU - Finelli, Lyn AU - Gubareva, Larisa AU - Fry, Alicia M AD - Epidemic Intelligence Service; Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, sGarg1@cdc.gov Y1 - 2013/03/15/ PY - 2013 DA - 2013 Mar 15 SP - 966 EP - 973 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 207 IS - 6 SN - 0022-1899, 0022-1899 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - influenza B virus KW - neuraminidase substitution KW - oseltamivir KW - antiviral resistance KW - USA, North Carolina KW - Influenza B KW - Viruses KW - Disease control KW - Infection KW - Influenza B virus KW - Oseltamivir KW - Influenza KW - Prevention KW - USA, South Carolina KW - Infectious diseases KW - Reviews KW - Exo- alpha -sialidase KW - H 0500:General KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1642623576?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=A+Cluster+of+Patients+Infected+With+I221V+Influenza+B+Virus+Variants+With+Reduced+Oseltamivir+Susceptibility-North+Carolina+and+South+Carolina%2C+2010-2011&rft.au=Garg%2C+Shikha%3BMoore%2C+Zack%3BLee%2C+Nicole%3BMcKenna%2C+John%3BBishop%2C+Amber%3BFleischauer%2C+Aaron%3BSprings%2C+Chasisity+B%3BNguyen%2C+Ha+T%3BSheu%2C+Tiffany+G%3BSleeman%2C+Katrina%3BFinelli%2C+Lyn%3BGubareva%2C+Larisa%3BFry%2C+Alicia+M&rft.aulast=Garg&rft.aufirst=Shikha&rft.date=2013-03-15&rft.volume=207&rft.issue=6&rft.spage=966&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjis776 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Influenza B; Reviews; Disease control; Exo- alpha -sialidase; Infection; Oseltamivir; Influenza; Prevention; Infectious diseases; Viruses; Influenza B virus; USA, North Carolina; USA, South Carolina DO - http://dx.doi.org/10.1093/infdis/jis776 ER - TY - JOUR T1 - Recent Advances in Research of HIV Infection: Implications of Viral and Host Genetics on Treatment and Prevention AN - 1773913906; PQ0002709484 AB - The genetic diversity among human immunodeficiency virus (HIV) subtypes as well as the variability of viral sequences found in HIV-infected individuals presents a number of difficult obstacles for the development of universally effective HIV treatment and prevention methods. Here, we present a brief summary of recent developments in the analysis of viral genetics and human genomics to provide insight into future methods for HIV treatment and prevention. Recent studies have mined viral sequences found in newly infected individuals to identify common features of all transmitted viruses that could provide potential targets for HIV vaccine development. Analysis of human immunogenetics has identified specific alleles associated with reduced virus loads in HIV-infected individuals providing valuable information that may influence individual responses to treatment and prevention methods. Increased sensitivity of antiretroviral drug resistance testing has improved the detection of hidden drug resistant virus but also highlighted the potential for drug resistant viruses to reduce the effectiveness of clinical treatment regimens. The rapidly expanding amount of data generated by studies of viral genetics and human immunogenetics will provide valuable information to guide the design of new strategies to improve clinical treatment and enhance HIV vaccine development. Copyright copyright 2013 S. Karger AG, Basel JF - Public Health Genomics AU - Haaland, R E AU - Johnson, JA AU - Tang, J AD - Laboratory Branch, Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Ga. Y1 - 2013/03// PY - 2013 DA - March 2013 SP - 31 EP - 36 PB - S. Karger AG, P.O. Box Basel CH-4009 Switzerland VL - 16 IS - 1-2 SN - 1662-4246, 1662-4246 KW - Virology & AIDS Abstracts; Genetics Abstracts; Health & Safety Science Abstracts KW - AIDS KW - Antiretroviral drug resistance KW - Human immunodeficiency virus KW - Immunogenetics KW - Transmission KW - Sensitivity KW - Data processing KW - Drug resistance KW - Viruses KW - Genetic diversity KW - Infection KW - Public health KW - Disease transmission KW - Prevention KW - Antiviral agents KW - Vaccines KW - genomics KW - Drugs KW - V 22360:AIDS and HIV KW - G 07730:Development & Cell Cycle KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1773913906?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Public+Health+Genomics&rft.atitle=Recent+Advances+in+Research+of+HIV+Infection%3A+Implications+of+Viral+and+Host+Genetics+on+Treatment+and+Prevention&rft.au=Haaland%2C+R+E%3BJohnson%2C+JA%3BTang%2C+J&rft.aulast=Haaland&rft.aufirst=R&rft.date=2013-03-01&rft.volume=16&rft.issue=1-2&rft.spage=31&rft.isbn=&rft.btitle=&rft.title=Public+Health+Genomics&rft.issn=16624246&rft_id=info:doi/10.1159%2F000345935 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-03-01 N1 - Last updated - 2016-09-14 N1 - SubjectsTermNotLitGenreText - Data processing; Immunogenetics; Antiviral agents; Drug resistance; Genetic diversity; genomics; Vaccines; Infection; Disease transmission; Public health; Sensitivity; Prevention; Human immunodeficiency virus; Viruses; Drugs DO - http://dx.doi.org/10.1159/000345935 ER - TY - JOUR T1 - Evaluation of an HIV Prevention Intervention Designed for African American Women: Results from the SISTA Community-Based Organization Behavioral Outcomes Project AN - 1642621828; 21178827 AB - One of the Centers for Disease Control and Prevention's strategies for addressing racial disparities within the HIV epidemic is to support the implementation of HIV prevention behavioral interventions designed for African Americans. One such intervention is Sisters Informing Sisters about Topics on AIDS (SISTA), a culturally relevant and gender-specific, five-session, group-level, HIV prevention intervention designed for African American women. In 2008, the Centers for Disease Control and Prevention funded five community-based organizations to conduct outcome monitoring of SISTA to assess the outcomes associated with implementation in the field. Using a 90-day recall, demographic and sexual risk data were collected from participants at baseline and at 90 and 180 days post-intervention. Findings reveal that women participating in SISTA (n = 432) demonstrated a significant reduction in sexual risk between baseline and both follow-up time points for each of the six outcomes being measured (e.g., any unprotected sex, all protected sex). JF - AIDS and Behavior AU - Sapiano, Tobey N AU - Moore, A AU - Kalayil, E J AU - Zhang, X AU - Chen, B AU - Uhl, G AU - Patel-Larson, A AU - Williams, W AD - Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road, MS-E59, Atlanta, GA, 30333, US, gvf8@cdc.gov Y1 - 2013/03// PY - 2013 DA - Mar 2013 SP - 1052 EP - 1067 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 17 IS - 3 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Risk Abstracts KW - Risk assessment KW - Acquired immune deficiency syndrome KW - Data processing KW - Epidemics KW - Community involvement KW - Disease control KW - Intervention KW - Demography KW - Prevention KW - Human immunodeficiency virus KW - Gender KW - Females KW - Ethnic groups KW - Sex KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1642621828?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Evaluation+of+an+HIV+Prevention+Intervention+Designed+for+African+American+Women%3A+Results+from+the+SISTA+Community-Based+Organization+Behavioral+Outcomes+Project&rft.au=Sapiano%2C+Tobey+N%3BMoore%2C+A%3BKalayil%2C+E+J%3BZhang%2C+X%3BChen%2C+B%3BUhl%2C+G%3BPatel-Larson%2C+A%3BWilliams%2C+W&rft.aulast=Sapiano&rft.aufirst=Tobey&rft.date=2013-03-01&rft.volume=17&rft.issue=3&rft.spage=1052&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-012-0292-0 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Number of references - 32 N1 - Last updated - 2015-03-04 N1 - SubjectsTermNotLitGenreText - Demography; Acquired immune deficiency syndrome; Epidemics; Data processing; Disease control; Sex; Risk assessment; Prevention; Human immunodeficiency virus; Community involvement; Gender; Intervention; Females; Ethnic groups DO - http://dx.doi.org/10.1007/s10461-012-0292-0 ER - TY - JOUR T1 - Prevalence and Predictors of Drug Use Among Adolescents with HIV Infection Acquired Perinatally or Later in Life AN - 1642614663; 21178812 AB - We examined the prevalence and predictors of drug use among a diverse group of adolescents living with HIV infection acquired perinatally or through sexual risk behaviors ("behaviorally acquired"). Adolescents ages 13-21 (n = 166) who were receiving care at one of five pediatric/adolescent HIV clinics in three US cities (Baltimore MD, Washington DC, and New York NY) and were enrolled in a behavioral intervention were interviewed at baseline regarding lifetime drug use experiences and depression symptoms. A majority of study participants reported using alcohol (57.2%) and marijuana (51.2%); 48.8% reported tobacco/cigarette use. The mean age of onset of use for each type of drug was 14 years or younger. A larger proportion of participants with behaviorally acquired HIV than adolescents with perinatally acquired HIV reported lifetime use of alcohol (76.1 vs. 44.4%), marijuana (73.1 vs. 36.4%), tobacco (70.2 vs. 34.3%), and club drugs (22.4 vs. 3%) (all p < 0.001).Original Abstract: Examinamos la prevalencia y los factores de prediccion del consumo de drogas en un grupo diverso de adolescentes que tienen infeccion por el VIH, adquirida en la etapa perinatal o a traves de conductas de riesgo sexuales ("adquisicion conductual"). Al inicio del estudio se entrevisto a adolescentes de 13 a 21 de edad (n = 166) que recibian atencion medica en una de cinco clinicas de VIH pediatricas o para adolescentes en tres ciudades de los EE. UU. (Baltimore MD, Washington DC y la Ciudad de Nueva York) y que participaban en una intervencion conductual, con relacion a sus experiencias con el consumo de drogas durante gran parte de su vida y los sintomas de depresion. Una mayoria de los participantes del estudio reporto consumir alcohol (57.2%) y marihuana (51.2%); 48.8% reporto consumo de cigarrillos o tabaco. La media de edad del comienzo del consumo para cada tipo de droga fue 14 anos o menos. Una mayor proporcion de participantes con VIH adquirido en forma conductual en comparacion con los que adquirieron el VIH en la etapa perinatal reporto gran parte de su vida consumo de alcohol (76.1 frente a 44.4%), marihuana (73.1 frente a 36.4%), tabaco (70.2 frente a 34.3%) y drogas de club (22.4 frente a 3%) (toda p < 0.001). JF - AIDS and Behavior AU - Conner, Latoya C AU - Wiener, Jeffrey AU - Lewis, Jennifer V AU - Phill, Rhonda AU - Peralta, Ligia AU - Chandwani, Sulachni AU - Koenig, Linda J AD - Children's National Medical Center, Washington, DC, USA, lek5@cdc.gov Y1 - 2013/03// PY - 2013 DA - Mar 2013 SP - 976 EP - 986 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 17 IS - 3 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - Acquired immune deficiency syndrome KW - Age KW - Cigarettes KW - Intervention KW - USA, Maryland, Baltimore KW - Drug abuse KW - Infection KW - Sexual behavior KW - Cities KW - Tobacco KW - Cannabis KW - alcohols KW - Drugs KW - Adolescents KW - Alcohol KW - Depression KW - Pediatrics KW - Adolescence KW - USA, New York KW - Human immunodeficiency virus KW - USA, Washington, D.C. KW - V 22360:AIDS and HIV KW - H 4000:Food and Drugs KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1642614663?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Prevalence+and+Predictors+of+Drug+Use+Among+Adolescents+with+HIV+Infection+Acquired+Perinatally+or+Later+in+Life&rft.au=Conner%2C+Latoya+C%3BWiener%2C+Jeffrey%3BLewis%2C+Jennifer+V%3BPhill%2C+Rhonda%3BPeralta%2C+Ligia%3BChandwani%2C+Sulachni%3BKoenig%2C+Linda+J&rft.aulast=Conner&rft.aufirst=Latoya&rft.date=2013-03-01&rft.volume=17&rft.issue=3&rft.spage=976&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-011-9950-x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Number of references - 54 N1 - Last updated - 2015-04-02 N1 - SubjectsTermNotLitGenreText - Age; Depression; Cigarettes; Pediatrics; Adolescence; alcohols; Cannabis; Tobacco; Infection; Sexual behavior; Drugs; Alcohol; Acquired immune deficiency syndrome; Intervention; Drug abuse; Cities; Human immunodeficiency virus; Adolescents; USA, Maryland, Baltimore; USA, Washington, D.C.; USA, New York DO - http://dx.doi.org/10.1007/s10461-011-9950-x ER - TY - JOUR T1 - HIV risk perception among men who have sex with men in two municipalities of China- implications for education and intervention AN - 1355850537; 4441764 AB - Men who have sex with men (MSM) are recognized as being at high risk for HIV infection. While studies have found that the prevalence of risky behaviors routinely remained high among MSM, few have focused on reasons why MSM may perceive they were or were not at risk for HIV infection. The objective of this study was to examine HIV risk perception among MSM in Beijing and Chongqing, China. A qualitative study consisting of eight focus group discussions and 65 in-depth interviews were conducted with MSM in the two cities. Participants felt that most MSM were aware of the high prevalence of HIV infection among MSM. Yet despite this awareness, most participants thought it was unlikely they would become infected with HIV. The reasons raised by participants included: AIDS was a foreign disease, cleaning after sex prevented transmission, being the insertive partner during sex was not risky, their partner(s) could be trusted, and feeling lucky made HIV/AIDS acquisition unlikely. The findings of this study suggest that a multi-pronged and tailored approach is needed to increase risk perception and safe sex behaviors among MSM in China. This may be achieved through HIV/AIDS interventions that use MSM-friendly media targeting misconceptions of HIV risk, stigma, and discrimination rather than simply distributing condoms. Reprinted by permission of Routledge, Taylor & Francis Ltd. JF - AIDS care AU - Ma, Wei AU - Ding, Xianbin AU - Lu, Hongyan AU - Ma, Xiaoyan AU - Xia, Dongyan AU - Lu, Rongrong AU - Xu, Jing AU - He, Xiong AU - Feng, Liangui AU - Fan, Song AU - Sun, Jiangping AU - Wilson, Erin C AU - Raymond, H Fisher AU - McFarland, Willi AU - Jia, Yujiang AU - Shao, Yiming AU - Xiao, Yan AU - Ruan, Yuhua AD - Shandong University ; Institute of AIDS Prevention and Control, Chongqing ; Beijing Municipal Center for Disease Control and Prevention ; Chinese Center for Disease Control and Prevention ; San Francisco Department of Public Health ; Vanderbilt University Y1 - 2013/03// PY - 2013 DA - Mar 2013 SP - 385 EP - 389 VL - 25 IS - 3 SN - 0954-0121, 0954-0121 KW - Sociology KW - Qualitative analysis KW - Risk KW - Education KW - Prevention KW - AIDS KW - HIV KW - Sexual intercourse KW - China KW - Sexually transmitted diseases KW - Homosexuals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1355850537?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+care&rft.atitle=HIV+risk+perception+among+men+who+have+sex+with+men+in+two+municipalities+of+China-+implications+for+education+and+intervention&rft.au=Ma%2C+Wei%3BDing%2C+Xianbin%3BLu%2C+Hongyan%3BMa%2C+Xiaoyan%3BXia%2C+Dongyan%3BLu%2C+Rongrong%3BXu%2C+Jing%3BHe%2C+Xiong%3BFeng%2C+Liangui%3BFan%2C+Song%3BSun%2C+Jiangping%3BWilson%2C+Erin+C%3BRaymond%2C+H+Fisher%3BMcFarland%2C+Willi%3BJia%2C+Yujiang%3BShao%2C+Yiming%3BXiao%2C+Yan%3BRuan%2C+Yuhua&rft.aulast=Ma&rft.aufirst=Wei&rft.date=2013-03-01&rft.volume=25&rft.issue=3&rft.spage=385&rft.isbn=&rft.btitle=&rft.title=AIDS+care&rft.issn=09540121&rft_id=info:doi/10.1080%2F09540121.2012.701727 LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 482 3617 6220; 5703 3617 6220; 5971; 11567 11563 1025 1542 11325 6071; 11581 3617 6220; 10072; 4049; 11035; 10519 3279 971 3286; 93 116 30 DO - http://dx.doi.org/10.1080/09540121.2012.701727 ER - TY - JOUR T1 - Broadening access to medical care during a severe influenza pandemic: the CDC nurse triage line project. AN - 1349399056; 23458098 AB - The impact of a severe influenza pandemic could be overwhelming to hospital emergency departments, clinics, and medical offices if large numbers of ill people were to simultaneously seek care. While current planning guidance to reduce surge on hospitals and other medical facilities during a pandemic largely focuses on improving the "supply" of medical care services, attention on reducing "demand" for such services is needed by better matching patient needs with alternative types and sites of care. Based on lessons learned during the 2009 H1N1 pandemic, the Centers for Disease Control and Prevention and its partners are currently exploring the acceptability and feasibility of using a coordinated network of nurse triage telephone lines during a pandemic to assess the health status of callers, help callers determine the most appropriate site for care (eg, hospital ED, outpatient center, home), disseminate information, provide clinical advice, and provide access to antiviral medications for ill people, if appropriate. As part of this effort, the integration and coordination of poison control centers, existing nurse advice lines, 2-1-1 information lines, and other hotlines are being investigated. JF - Biosecurity and bioterrorism : biodefense strategy, practice, and science AU - Koonin, Lisa M AU - Hanfling, Dan AD - Pandemic Medical Care and Countermeasures Task Force, Influenza Coordination Unit, Office of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA. LKoonin@cdc.gov Y1 - 2013/03// PY - 2013 DA - March 2013 SP - 75 EP - 80 VL - 11 IS - 1 KW - Index Medicus KW - United States KW - Public-Private Sector Partnerships KW - Centers for Disease Control and Prevention (U.S.) KW - Humans KW - Poison Control Centers -- organization & administration KW - Information Dissemination KW - Nurse's Role KW - Hotlines -- organization & administration KW - Influenza, Human -- epidemiology KW - Triage -- organization & administration KW - Pandemics KW - Health Services Accessibility -- organization & administration KW - Influenza, Human -- therapy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1349399056?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biosecurity+and+bioterrorism+%3A+biodefense+strategy%2C+practice%2C+and+science&rft.atitle=Broadening+access+to+medical+care+during+a+severe+influenza+pandemic%3A+the+CDC+nurse+triage+line+project.&rft.au=Koonin%2C+Lisa+M%3BHanfling%2C+Dan&rft.aulast=Koonin&rft.aufirst=Lisa&rft.date=2013-03-01&rft.volume=11&rft.issue=1&rft.spage=75&rft.isbn=&rft.btitle=&rft.title=Biosecurity+and+bioterrorism+%3A+biodefense+strategy%2C+practice%2C+and+science&rft.issn=1557-850X&rft_id=info:doi/10.1089%2Fbsp.2013.0012 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2013-11-14 N1 - Date created - 2013-03-29 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1089/bsp.2013.0012 ER - TY - JOUR T1 - Relative Importance of Emotional Dysregulation, Hostility, and Impulsiveness in Predicting Intimate Partner Violence Perpetrated by Men in Alcohol Treatment AN - 1347818610; 201307691 AB - The current study employs dominance analysis to assess the relative importance of three constructs -- hostility, impulsiveness, and emotional dysregulation (difficulties managing one's emotions when experiencing negative emotion or distress) -- in explaining psychological, physical, and sexual intimate partner violence (IPV) perpetration by men seeking alcohol treatment. A sample of 121 predominantly White, heterosexual men (average age 33.28, range = 18-62) enrolled in residential substance abuse treatment completed measures of emotional dysregulation, hostility, and impulsiveness, which are three highly related constructs identified as risk factors for both substance use disorders and IPV. The constructs collectively accounted for 20-25% of the variance in each form of IPV. Because impulsiveness, hostility, and emotional dysregulation are highly correlated, dominance analysis was used to examine which factor most strongly predicted each form of IPV. Dominance analysis findings favored hostility as a predictor of physical IPV perpetration and impulsiveness as a predictor of sexual and psychological IPV perpetration. Differential associations between the constructs and each form of IPV may be used to inform assessment and treatment planning of men who abuse alcohol. Better understanding, preventing, and treating male-to-female IPV will protect women from the far-reaching consequences of this violence. Adapted from the source document. JF - Psychology of Women Quarterly AU - Tharp, Andra Teten AU - Schumacher, Julie A AU - Samper, Rita E AU - McLeish, Alison C AU - Coffey, Scott F AD - National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA, USA atharp@cdc.gov Y1 - 2013/03// PY - 2013 DA - March 2013 SP - 51 EP - 60 PB - Sage Publications Inc, CA VL - 37 IS - 1 SN - 0361-6843, 0361-6843 KW - intimate partner violence hostility impulsiveness emotional dysregulation alcohol abuse KW - Hostility KW - Men KW - Abusive relationships KW - Emotional regulation KW - Impulsivity KW - Dominance KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1347818610?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Psychology+of+Women+Quarterly&rft.atitle=Relative+Importance+of+Emotional+Dysregulation%2C+Hostility%2C+and+Impulsiveness+in+Predicting+Intimate+Partner+Violence+Perpetrated+by+Men+in+Alcohol+Treatment&rft.au=Tharp%2C+Andra+Teten%3BSchumacher%2C+Julie+A%3BSamper%2C+Rita+E%3BMcLeish%2C+Alison+C%3BCoffey%2C+Scott+F&rft.aulast=Tharp&rft.aufirst=Andra&rft.date=2013-03-01&rft.volume=37&rft.issue=1&rft.spage=51&rft.isbn=&rft.btitle=&rft.title=Psychology+of+Women+Quarterly&rft.issn=03616843&rft_id=info:doi/10.1177%2F0361684312461138 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2013-05-01 N1 - Last updated - 2016-09-27 N1 - CODEN - PWOQDY N1 - SubjectsTermNotLitGenreText - Abusive relationships; Impulsivity; Hostility; Men; Emotional regulation; Dominance DO - http://dx.doi.org/10.1177/0361684312461138 ER - TY - JOUR T1 - Does discussing sexually transmissible infections or HIV with a parent increase condom use among young women using other contraceptive methods? AN - 1347818206; 201305667 AB - Background: Young people may be more likely to use condoms if they discuss sexual risks with their parents. However, no previous study has examined whether discussing sexual risks with a parent is differently associated with condom use among women using and not using other contraceptive methods. Methods: Using weighted data from the 2006-2008 National Survey of Family Growth, we examined condom use at last sex among 1206 sexually active unmarried women aged 15-24 years. Using logistic regression, we examined the association between condom use and discussing sexually transmissible infections (STIs) with parents before the age of 18 years, adjusted for women's characteristics (age, ethnicity, income and condom use at first sex). We estimated the predicted probability of condom use by whether women discussed STIs with parents, stratified by use of other contraceptive methods. Results: Overall, 53% of women used condoms at last sex. Among 564 women using other contraceptives, 42% used condoms, versus 64% of 642 women not using other contraceptive methods (P < 0.01). After adjustment for covariates, the predicted probability of condom use among women using other contraceptives was 47% among women who discussed STIs with their parents (v. 31% of those not discussing STIs; P < 0.01). Among women not using other contraceptives, the predicted probability of condom use remained 64% regardless of whether they discussed STIs with their parents. Conclusions: Young women who use other contraceptive methods are less likely to use condoms, but discussing STIs with parents is associated with increased condom use among these women. Adapted from the source document. JF - Sexual Health AU - Bradley, Heather AU - Leichliter, Jami S AU - Gift, Thomas L AD - Centers for Disease Control and Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, Division of STD Prevention, 1600 Clifton Rd, Atlanta, GA 30333, USA Y1 - 2013/03// PY - 2013 DA - March 2013 SP - 82 EP - 90 PB - CSIRO Publishing, Collingwood Australia VL - 10 IS - 1 SN - 1448-5028, 1448-5028 KW - birth control, oral contraceptive pill, United States KW - Condoms KW - Young women KW - Women KW - Parents KW - Sexually transmitted diseases KW - Contraceptives KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1347818206?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Sexual+Health&rft.atitle=Does+discussing+sexually+transmissible+infections+or+HIV+with+a+parent+increase+condom+use+among+young+women+using+other+contraceptive+methods%3F&rft.au=Bradley%2C+Heather%3BLeichliter%2C+Jami+S%3BGift%2C+Thomas+L&rft.aulast=Bradley&rft.aufirst=Heather&rft.date=2013-03-01&rft.volume=10&rft.issue=1&rft.spage=82&rft.isbn=&rft.btitle=&rft.title=Sexual+Health&rft.issn=14485028&rft_id=info:doi/10.1071%2FSH12091 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2013-05-01 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Condoms; Women; Parents; Contraceptives; Young women; Sexually transmitted diseases DO - http://dx.doi.org/10.1071/SH12091 ER - TY - JOUR T1 - Comparison of the Sensitivity of Laboratory Diagnostic Methods from a Well-Characterized Outbreak of Mumps in New York City in 2009 AN - 1323809603; 17819216 AB - A mumps outbreak in upstate New York in 2009 at a summer camp for Orthodox Jewish boys spread into Orthodox Jewish communities in the Northeast, including New York City. The availability of epidemiologic information, including vaccination records and parotitis onset dates, allowed an enhanced analysis of laboratory methods for mumps testing. Serum and buccal swab samples were collected from 296 confirmed cases with onsets from September through December 2009. All samples were tested using the Centers for Disease Control and Prevention (CDC) capture IgM enzyme immunoassay (EIA) and a real-time reverse transcription-PCR (rRT-PCR) that targets the short hydrophobic gene. A subset of the samples (n = 205) was used to evaluate 3 commercial mumps IgM assays and to assess the sensitivity of using an alternative target gene (nucleoprotein) in the rRT-PCR protocol. Among 115 cases of mumps with 2 documented doses of measles, mumps, and rubella (MMR) vaccine, the CDC capture IgM EIA detected IgM in 51% of serum samples compared to 9% to 24% using three commercial IgM assays. The rRT-PCR that targeted the nucleoprotein gene increased RNA detection by 14% compared to that obtained with the original protocol. The ability to detect IgM improved when serum was collected 3 days or more after symptom onset, whereas sensitivity of RNA detection by rRT-PCR declined when buccal swabs were collected later than 2 days after onset. Selection of testing methods and timing of sample collection are important factors in the ability to confirm infection among vaccinated persons. These results reinforce the need to use virus detection assays in addition to serologic tests. JF - Clinical and Vaccine Immunology AU - Rota, Jennifer S AU - Rosen, Jennifer B AU - Doll, Margaret K AU - McNall, Rebecca J AU - McGrew, Marcia AU - Williams, Nobia AU - Lopareva, Elena N AU - Barskey, Albert E AU - Punsalang, Amado Jr AU - Rota, Paul A AD - Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, JenniferS.Rota,jrota{at}cdc.gov. Y1 - 2013/03// PY - 2013 DA - March 2013 SP - 391 EP - 396 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 20 IS - 3 SN - 1556-6811, 1556-6811 KW - Environment Abstracts; Health & Safety Science Abstracts; Virology & AIDS Abstracts; Immunology Abstracts KW - Measles KW - Nucleoproteins KW - Disease control KW - Summer KW - Hydrophobicity KW - Infection KW - Rubella KW - USA, New York, New York City KW - Laboratory methods KW - Urban areas KW - Sensitivity KW - Immunology KW - Cyclic AMP KW - Enzymes KW - Vaccination KW - Enzyme immunoassay KW - Prevention KW - RNA KW - Outbreaks KW - Vaccines KW - Immunoassays KW - Parotitis KW - Immunoglobulin M KW - Mumps KW - V 22350:Immunology KW - F 06905:Vaccines KW - H 4000:Food and Drugs KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1323809603?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+and+Vaccine+Immunology&rft.atitle=Comparison+of+the+Sensitivity+of+Laboratory+Diagnostic+Methods+from+a+Well-Characterized+Outbreak+of+Mumps+in+New+York+City+in+2009&rft.au=Rota%2C+Jennifer+S%3BRosen%2C+Jennifer+B%3BDoll%2C+Margaret+K%3BMcNall%2C+Rebecca+J%3BMcGrew%2C+Marcia%3BWilliams%2C+Nobia%3BLopareva%2C+Elena+N%3BBarskey%2C+Albert+E%3BPunsalang%2C+Amado+Jr%3BRota%2C+Paul+A&rft.aulast=Rota&rft.aufirst=Jennifer&rft.date=2013-03-01&rft.volume=20&rft.issue=3&rft.spage=391&rft.isbn=&rft.btitle=&rft.title=Clinical+and+Vaccine+Immunology&rft.issn=15566811&rft_id=info:doi/10.1128%2FCVI.00660-12 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-04-01 N1 - Number of references - 23 N1 - Last updated - 2016-07-07 N1 - SubjectsTermNotLitGenreText - Measles; Nucleoproteins; Cyclic AMP; Disease control; Hydrophobicity; Infection; Rubella; Vaccination; Enzyme immunoassay; RNA; Vaccines; Mumps; Immunoglobulin M; Parotitis; Sensitivity; Prevention; Laboratory methods; Immunology; Enzymes; Summer; Outbreaks; Immunoassays; Urban areas; USA, New York, New York City DO - http://dx.doi.org/10.1128/CVI.00660-12 ER - TY - JOUR T1 - Detection of the A2058G and A2059G 23S rRNA Gene Point Mutations Associated with Azithromycin Resistance in Treponema pallidum by Use of a TaqMan Real-Time Multiplex PCR Assay AN - 1323800646; 17760261 AB - Macrolide treatment failure in syphilis patients is associated with a single point mutation (either A2058G or A2059G) in both copies of the 23S rRNA gene in Treponema pallidum strains. The conventional method for the detection of both point mutations uses nested PCR combined with restriction enzyme digestions, which is laborious and time-consuming. We initially developed a TaqMan-based real-time duplex PCR assay for detection of the A2058G mutation, and upon discovery of the A2059G mutation, we modified the assay into a triplex format to simultaneously detect both mutations. The point mutations detected by the real-time triplex PCR were confirmed by pyrosequencing. A total of 129 specimens PCR positive for T. pallidum that were obtained from an azithromycin resistance surveillance study conducted in the United States were analyzed. Sixty-six (51.2%) of the 129 samples with the A2058G mutation were identified by both real-time PCR assays. Of the remaining 63 samples that were identified as having a macrolide-susceptible genotype by the duplex PCR assay, 17 (27%) were found to contain the A2059G mutation by the triplex PCR. The proportions of macrolide-susceptible versus -resistant genotypes harboring either the A2058G or the A2059G mutation among the T. pallidum strains were 35.6, 51.2, and 13.2%, respectively. None of the T. pallidum strains examined had both point mutations. The TaqMan-based real-time triplex PCR assay offers an alternative to conventional nested PCR and restriction fragment length polymorphism analyses for the rapid detection of both point mutations associated with macrolide resistance in T. pallidum. JF - Journal of Clinical Microbiology AU - Chen, Cheng-Yen AU - Chi, Kai-Hua AU - Pillay, Allan AU - Nachamkin, Eli AU - Su, John R AU - Ballard, Ronald C AD - Laboratory Reference and Research Branch, Cheng-YenChen,cychen{at}cdc.gov. Y1 - 2013/03// PY - 2013 DA - Mar 2013 SP - 908 EP - 913 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 51 IS - 3 SN - 0095-1137, 0095-1137 KW - Genetics Abstracts; Microbiology Abstracts B: Bacteriology KW - rRNA KW - rRNA 23S KW - Azithromycin KW - Treponema pallidum KW - Globus pallidus KW - Point mutation KW - Restriction fragment length polymorphism KW - Polymerase chain reaction KW - Enzymes KW - Syphilis KW - G 07880:Human Genetics KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1323800646?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Detection+of+the+A2058G+and+A2059G+23S+rRNA+Gene+Point+Mutations+Associated+with+Azithromycin+Resistance+in+Treponema+pallidum+by+Use+of+a+TaqMan+Real-Time+Multiplex+PCR+Assay&rft.au=Chen%2C+Cheng-Yen%3BChi%2C+Kai-Hua%3BPillay%2C+Allan%3BNachamkin%2C+Eli%3BSu%2C+John+R%3BBallard%2C+Ronald+C&rft.aulast=Chen&rft.aufirst=Cheng-Yen&rft.date=2013-03-01&rft.volume=51&rft.issue=3&rft.spage=908&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.02770-12 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-04-01 N1 - Number of references - 27 N1 - Last updated - 2013-11-15 N1 - SubjectsTermNotLitGenreText - rRNA; rRNA 23S; Azithromycin; Point mutation; Globus pallidus; Restriction fragment length polymorphism; Enzymes; Polymerase chain reaction; Syphilis; Treponema pallidum DO - http://dx.doi.org/10.1128/JCM.02770-12 ER - TY - JOUR T1 - Presence and Persistence of Coxiella burnetii in the Environments of Goat Farms Associated with a Q Fever Outbreak AN - 1315611367; 17709862 AB - Q fever is a zoonotic disease caused by inhalation of the bacterium Coxiella burnetii. Ruminant livestock are common reservoirs for C. burnetii, and bacteria present in aerosols derived from the waste of infected animals can infect humans. The significance of infection from material deposited in the environment versus transmission directly from infected animals is not known. In 2011, an outbreak of Q fever cases on farms in Washington and Montana was associated with infected goats. A study was undertaken to investigate the quantity and spatial distribution of C. burnetii in the environment of these goat farms. Soil, vacuum, and sponge samples collected on seven farms epidemiologically linked to the outbreak were tested for the presence of C. burnetii DNA by quantitative PCR. Overall, 70.1% of the samples were positive for C. burnetii. All farms had positive samples, but the quantity of C. burnetii varied widely between samples and between farms. High quantities of C. burnetii DNA were in goat housing/birthing areas, and only small quantities were found in samples collected more than 50 m from these areas. Follow-up sampling at one of the farms 1 year after the outbreak found small quantities of C. burnetii DNA in air samples and large quantities of C. burnetii persisting in soil and vacuum samples. The results suggest that the highest concentrations of environmental C. burnetii are found in goat birthing areas and that contamination of other areas is mostly associated with human movement. JF - Applied and Environmental Microbiology AU - Kersh, Gilbert J AU - Fitzpatrick, Kelly A AU - Self, Joshua S AU - Priestley, Rachael A AU - Kelly, Aubree J AU - Lash, R Ryan AU - Marsden-Haug, Nicola AU - Nett, Randall J AU - Bjork, Adam AU - Massung, Robert F AD - Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, USA, GilbertJ.Kersh,gkersh{at}cdc.gov. Y1 - 2013/03// PY - 2013 DA - Mar 2013 SP - 1697 EP - 1703 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 79 IS - 5 SN - 0099-2240, 0099-2240 KW - Health & Safety Science Abstracts; Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Aerosols KW - Coxiella burnetii KW - Farms KW - USA, Montana KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - A:01330 KW - J:02400 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1315611367?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Presence+and+Persistence+of+Coxiella+burnetii+in+the+Environments+of+Goat+Farms+Associated+with+a+Q+Fever+Outbreak&rft.au=Kersh%2C+Gilbert+J%3BFitzpatrick%2C+Kelly+A%3BSelf%2C+Joshua+S%3BPriestley%2C+Rachael+A%3BKelly%2C+Aubree+J%3BLash%2C+R+Ryan%3BMarsden-Haug%2C+Nicola%3BNett%2C+Randall+J%3BBjork%2C+Adam%3BMassung%2C+Robert+F&rft.aulast=Kersh&rft.aufirst=Gilbert&rft.date=2013-03-01&rft.volume=79&rft.issue=5&rft.spage=1697&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/10.1128%2FAEM.03472-12 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-03-01 N1 - Number of references - 1 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Farms; Coxiella burnetii; USA, Montana DO - http://dx.doi.org/10.1128/AEM.03472-12 ER - TY - JOUR T1 - Relationship between adverse childhood experiences and unemployment among adults from five US states AN - 1315607801; 17688692 AB - Purpose: Our study assesses the relationships between self-reported adverse childhood experiences (ACEs) (including sexual, physical, or verbal abuse, along with household dysfunction including parental separation or divorce, domestic violence, mental illness, substance abuse, or incarcerated household member) and unemployment status in five US states in 2009. Methods: We examined these relationships using the 2009 Behavioral Risk Factor Surveillance System survey data from 17,469 respondents (aged 18-64 years) who resided in five states, completed the ACE Questionnaire, and provided socio-demographic and social support information. We also assessed the mediation of these relationships by respondents' educational attainment, marital status, and social support. Results: About two-third of respondents reported having had at least one ACEs, while 15.1 % of men and 19.3 % of women reported having had greater than or equal to 4 ACEs. Among both men and women, the unemployment rate in 2009 was significantly higher among those who reported having had any ACE than among those who reported no ACEs (p < 0.05). Educational attainment, marital status, and social support mediated the relationship between ACEs and unemployment, particularly among women. Conclusions: ACEs appear to be associated with increased risk for unemployment among men and women. Further studies may be needed to better understand how education, marital status, and social support mediate the association between multiple ACEs and unemployment. JF - Social Psychiatry and Psychiatric Epidemiology AU - Liu, Yong AU - Croft, Janet B AU - Chapman, Daniel P AU - Perry, Geraldine S AU - Greenlund, Kurt J AU - Zhao, Guixiang AU - Edwards, Valerie J AD - Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention (CDC), 4770 Buford Highway, NE, Mail-Stop K-67, Atlanta, GA, 30341, USA, ikd8@cdc.gov Y1 - 2013/03// PY - 2013 DA - Mar 2013 SP - 357 EP - 369 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 48 IS - 3 SN - 0933-7954, 0933-7954 KW - Risk Abstracts KW - Children KW - Domestic violence KW - Education KW - Households KW - Marriage KW - Prisons KW - Risk factors KW - Substance abuse KW - Unemployment KW - USA KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1315607801?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Social+Psychiatry+and+Psychiatric+Epidemiology&rft.atitle=Relationship+between+adverse+childhood+experiences+and+unemployment+among+adults+from+five+US+states&rft.au=Liu%2C+Yong%3BCroft%2C+Janet+B%3BChapman%2C+Daniel+P%3BPerry%2C+Geraldine+S%3BGreenlund%2C+Kurt+J%3BZhao%2C+Guixiang%3BEdwards%2C+Valerie+J&rft.aulast=Liu&rft.aufirst=Yong&rft.date=2013-03-01&rft.volume=48&rft.issue=3&rft.spage=357&rft.isbn=&rft.btitle=&rft.title=Social+Psychiatry+and+Psychiatric+Epidemiology&rft.issn=09337954&rft_id=info:doi/10.1007%2Fs00127-012-0554-1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-03-01 N1 - Number of references - 59 N1 - Last updated - 2013-03-22 N1 - SubjectsTermNotLitGenreText - Prisons; Education; Unemployment; Risk factors; Households; Marriage; Domestic violence; Children; Substance abuse; USA DO - http://dx.doi.org/10.1007/s00127-012-0554-1 ER - TY - JOUR T1 - Fatal unintentional injuries in the home in the U.S., 2000-2008. AN - 1288993091; 23415120 AB - From 1992 to 1999, an average of more than 18,000 unintentional home injury deaths occurred in the U.S. annually. The objective of this study was to provide current prevalence estimates of fatal unintentional injury in the home. Data from the 2000-2008 National Vital Statistics System were used in 2011 to calculate average annual rates for unintentional home injury deaths for the U.S. overall, and by mechanism of injury, gender, and age group. From 2000 to 2008, there was an annual average of 30,569 unintentional injury deaths occurring in the home environment in the U.S. (10.3 deaths per 100,000). Poisonings (4.5 per 100,000) and falls (3.5 per 100,000) were the leading causes of home injury deaths. Men/boys had higher rates of home injury death than women/girls (12.7 vs 8.2 per 100,000), and older adults (≥80 years) had higher rates than other age groups. Home injury deaths and rates increased significantly from 2000 to 2008. More than 30,000 people die annually in the U.S. from unintentional injuries at home, with the trend rising since the year 2000. The overall rise is due in large part to the dramatic increase in deaths due to poisonings, and to a lesser degree falls at home. Unintentional home injuries are both predictable and preventable. Through a multifaceted approach combining behavioral change, adequate supervision of children, installation and maintenance of safety devices, and adherence to building codes, safety regulations and legislation, home injuries can be reduced. Published by Elsevier Inc. JF - American journal of preventive medicine AU - Mack, Karin A AU - Rudd, Rose A AU - Mickalide, Angela D AU - Ballesteros, Michael F AD - Division of Unintentional Injury Prevention, National Center for Injury Prevention and Control, CDC, Atlanta, GA 30341, USA. kmack@cdc.gov Y1 - 2013/03// PY - 2013 DA - March 2013 SP - 239 EP - 246 VL - 44 IS - 3 KW - Index Medicus KW - Young Adult KW - Age Factors KW - Sex Factors KW - Humans KW - Aged KW - Child KW - Child, Preschool KW - Infant KW - Aged, 80 and over KW - Adult KW - Middle Aged KW - Adolescent KW - Female KW - Male KW - Prevalence KW - Wounds and Injuries -- epidemiology KW - Accidents, Home -- prevention & control KW - Wounds and Injuries -- classification KW - Accidents, Home -- classification KW - Accidents, Home -- mortality KW - Wounds and Injuries -- mortality UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1288993091?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+journal+of+preventive+medicine&rft.atitle=Fatal+unintentional+injuries+in+the+home+in+the+U.S.%2C+2000-2008.&rft.au=Mack%2C+Karin+A%3BRudd%2C+Rose+A%3BMickalide%2C+Angela+D%3BBallesteros%2C+Michael+F&rft.aulast=Mack&rft.aufirst=Karin&rft.date=2013-03-01&rft.volume=44&rft.issue=3&rft.spage=239&rft.isbn=&rft.btitle=&rft.title=American+journal+of+preventive+medicine&rft.issn=1873-2607&rft_id=info:doi/10.1016%2Fj.amepre.2012.10.022 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2013-08-13 N1 - Date created - 2013-02-18 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Am J Prev Med. 2005 Jan;28(1):73-9 [15626560] Inj Prev. 2006 Dec;12 Suppl 2:ii49-ii54 [17170172] J Public Health Manag Pract. 2010 Sep-Oct;16(5 Suppl):S34-43 [20689373] MMWR Morb Mortal Wkly Rep. 2011 Nov 4;60(43):1487-92 [22048730] NCHS Data Brief. 2011 Dec;(81):1-8 [22617462] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.amepre.2012.10.022 ER - TY - JOUR T1 - Localization of pandemic 2009 H1N1 influenza A virus RNA in lung and lymph nodes of fatal influenza cases by in situ hybridization: New insights on virus replication and pathogenesis AN - 1285095203; 17612109 AB - Pandemic 2009 H1N1 influenza A (pH1N1) virus has caused substantial morbidity and mortality globally and continues to circulate. Although pH1N1 viral antigens have been demonstrated in various human tissues by immunohistochemistry (IHC), cellular localization of pH1N1 RNA in these tissues has largely remained uninvestigated. To examine the distribution of pH1N1 RNA in tissues of fatal cases in order to understand the virus tissue tropism, replication and disease pathogenesis. Formalin-fixed, paraffin embedded autopsy tissues from 21 patients with confirmed pH1N1 infection were analyzed by influenza A IHC and by in situ hybridization (ISH) using DIG-labeled sense (detects viral RNA) and antisense probes (detects positive-stranded mRNA and cRNA) targeting the nucleoprotein gene of pH1N1 virus. pH1N1 RNA was localized by ISH in 57% of cases while viral antigens were detected by IHC in 76%. However, in cases with a short duration of illness (1-3 days), more cases (69%) were positive by ISH than IHC (62%). Strong ISH staining was detected by antisense probes in the alveolar pneumocytes of the lungs, mucous glands and in lymph nodes. IHC staining of viral antigens was demonstrated in the lung pneumocytes and mucous glands, but no immunostaining was detected in any of the lymph nodes examined. This study demonstrates cellular localization of positive-stranded pH1N1 RNA in the lungs, mucous glands and lymph nodes that suggests viral replication in these tissues. The novel ISH assay can be a useful adjunct for the detection of pH1N1 virus in tissues and for pathogenesis studies. JF - Journal of Clinical Virology AU - Bhatnagar, Julu AU - Jones, Tara AU - Blau, Dianna M AU - Shieh, Wun-Ju AU - Paddock, Christopher D AU - Drew, Clifton AU - Denison, Amy M AU - Rollin, Dominique C AU - Patel, Mitesh AU - Zaki, Sherif R AD - Infectious Diseases Pathology Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA, JBhatnagar@cdc.gov Y1 - 2013/03// PY - 2013 DA - Mar 2013 SP - 316 EP - 321 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 56 IS - 3 SN - 1386-6532, 1386-6532 KW - Health & Safety Science Abstracts; Biochemistry Abstracts 2: Nucleic Acids; Virology & AIDS Abstracts KW - Autopsy KW - DNA probes KW - pneumocytes KW - Influenza A KW - Nucleoproteins KW - RNA viruses KW - Infection KW - Morbidity KW - Influenza KW - pandemics KW - Antisense KW - RNA probes KW - Influenza A virus KW - Glands KW - Mortality KW - Paraffin KW - Replication KW - Tropism KW - Antisense RNA KW - Alveoli KW - Lymph nodes KW - mRNA KW - Lung KW - Immunohistochemistry KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - V 22320:Replication KW - N 14830:RNA UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1285095203?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Virology&rft.atitle=Localization+of+pandemic+2009+H1N1+influenza+A+virus+RNA+in+lung+and+lymph+nodes+of+fatal+influenza+cases+by+in+situ+hybridization%3A+New+insights+on+virus+replication+and+pathogenesis&rft.au=Bhatnagar%2C+Julu%3BJones%2C+Tara%3BBlau%2C+Dianna+M%3BShieh%2C+Wun-Ju%3BPaddock%2C+Christopher+D%3BDrew%2C+Clifton%3BDenison%2C+Amy+M%3BRollin%2C+Dominique+C%3BPatel%2C+Mitesh%3BZaki%2C+Sherif+R&rft.aulast=Bhatnagar&rft.aufirst=Julu&rft.date=2013-03-01&rft.volume=56&rft.issue=3&rft.spage=316&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Virology&rft.issn=13866532&rft_id=info:doi/10.1016%2Fj.jcv.2012.11.014 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-01 N1 - Last updated - 2013-06-14 N1 - SubjectsTermNotLitGenreText - Autopsy; Mortality; Paraffin; Replication; Influenza A; pneumocytes; DNA probes; Nucleoproteins; Antisense RNA; Tropism; RNA viruses; Infection; Morbidity; Lymph nodes; Alveoli; mRNA; Antisense; pandemics; RNA probes; Lung; Glands; Immunohistochemistry; Influenza; Influenza A virus DO - http://dx.doi.org/10.1016/j.jcv.2012.11.014 ER - TY - JOUR T1 - Drug resistance and mecA gene analysis in foodborne Staphylococcus aureus AN - 1508761279; 19377791 AB - Objective: To investigate the drug resistance to 12 kinds of antibiotics and detect mecA gene simultaneously in foodborne Staphylococcus aureus strains, meanwhile compare the drug-resistance status between two different origins. Methods: The disk diffusion method was used to detect drug-resistance, and the genotype was analyzed by PCR method. Results: Seven strains in 75 foodborne S. aureus were MRSA strains, including five strains carrying mecA gene. A total of 66 strains were MSSA trains, accounted for 88.0%, with one strain carrying mecA gene. Two strains were intermediate strains to oxacillin, all of that carry mecA gene, accounted for 2.67%. A total of 73 strains were penicillin G resistance, with overall resistant rate of 7.33%. Meanwhile the resistant rate were respectively 20.00% for tetracycline, 2.67% for gentamicin, 9.33% for norfloxacin, 60.00% for erythrocin, 5.33% for Chloromycetin, 33.33% for clindamycin, and 17.33% for neomycin. There were no resistant strains to rifampicin, vancomycin or novobiocin. Conclusion: The foodborne S. aureus strains were generally resistant to penicillin G, and some MRSA strains were detected; The foodborne MSSA strains are sensitive to most of antibiotics, while most of foodborne MRSA strains are multi-drug resistant strains. JF - Journal of Environment and Health AU - Lu, Guo-Ping AU - Wang, Xian AU - Wei, Xiu-Ping AU - Li, Jin-Shan AU - Feng, Pei AD - Institute of Microbiology Inspection, Shijiazhuang Center for Disease Control and Prevention, Shijiazhuang, Hebei 050000 PY - 2013 SP - 1089 EP - 1091 PB - Chinese Preventive Medical Association, Hualong Road, Hedong District Tianjin 300011 China VL - 30 IS - 12 SN - 1001-5914, 1001-5914 KW - Genetics Abstracts; Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts; Environment Abstracts KW - Clindamycin KW - Norfloxacin KW - Food KW - Drug resistance KW - Novobiocin KW - Oxacillin KW - Antibiotics KW - Genotypes KW - Tetracyclines KW - Penicillin KW - Gentamicin KW - Rifampin KW - MecA protein KW - Polymerase chain reaction KW - Vancomycin KW - Multidrug resistance KW - Diffusion KW - Neomycin KW - Staphylococcus aureus KW - J 02310:Genetics & Taxonomy KW - G 07750:Ecological & Population Genetics KW - ENA 18:Transportation KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1508761279?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environment+and+Health&rft.atitle=Drug+resistance+and+mecA+gene+analysis+in+foodborne+Staphylococcus+aureus&rft.au=Lu%2C+Guo-Ping%3BWang%2C+Xian%3BWei%2C+Xiu-Ping%3BLi%2C+Jin-Shan%3BFeng%2C+Pei&rft.aulast=Lu&rft.aufirst=Guo-Ping&rft.date=2013-02-01&rft.volume=30&rft.issue=12&rft.spage=1089&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environment+and+Health&rft.issn=10015914&rft_id=info:doi/ LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-03-01 N1 - Last updated - 2016-01-21 N1 - SubjectsTermNotLitGenreText - Norfloxacin; Clindamycin; Drug resistance; Food; Novobiocin; Oxacillin; Antibiotics; Genotypes; Tetracyclines; Penicillin; Gentamicin; Rifampin; MecA protein; Vancomycin; Polymerase chain reaction; Diffusion; Multidrug resistance; Neomycin; Staphylococcus aureus ER - TY - JOUR T1 - Progress with rotavirus vaccines: summary of the Tenth International Rotavirus Symposium AN - 1464503147; 18778044 AB - Tenth International Rotavirus Symposium Bangkok, Thailand, 19-21 September 2012 Over 350 scientific, public and private sector experts from 47 countries convened at the Tenth International Rotavirus Symposium in Bangkok, Thailand on 19-21 September 2012 to discuss progress in the prevention and control of rotavirus, the leading cause of diarrhea hospitalizations and deaths among young children worldwide. Participants discussed data on the burden and epidemiology of rotavirus disease, results of trials of rotavirus vaccines, postmarketing data on vaccine impact and safety from countries that have implemented rotavirus vaccination programs, new insights in rotavirus pathogenesis, immunity and strain diversity, and key issues related to vaccine policy and introduction. JF - Expert Review of Vaccines AU - Parashar, Umesh AU - Steele, Duncan AU - Neuzil, Kathleen AU - Quadros, Ciro de AU - Tharmaphornpilas, Piyanit AU - Serhan, Fatima AU - Santosham, Mathu AU - Patel, Manish AU - Glass, Roger AD - super(1)CDC, Atlanta, GA, USA, uap2@cdc.gov Y1 - 2013/02// PY - 2013 DA - Feb 2013 SP - 113 EP - 117 PB - Future Science Group (FSG), Unitec House, 2 Albert Place London N3 1QB United Kingdom VL - 12 IS - 2 SN - 1476-0584, 1476-0584 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Children KW - Rotavirus KW - Thailand, Chacoengsao Prov., Bangkok KW - Vaccines KW - V:22400 KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1464503147?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Expert+Review+of+Vaccines&rft.atitle=Progress+with+rotavirus+vaccines%3A+summary+of+the+Tenth+International+Rotavirus+Symposium&rft.au=Parashar%2C+Umesh%3BSteele%2C+Duncan%3BNeuzil%2C+Kathleen%3BQuadros%2C+Ciro+de%3BTharmaphornpilas%2C+Piyanit%3BSerhan%2C+Fatima%3BSantosham%2C+Mathu%3BPatel%2C+Manish%3BGlass%2C+Roger&rft.aulast=Parashar&rft.aufirst=Umesh&rft.date=2013-02-01&rft.volume=12&rft.issue=2&rft.spage=113&rft.isbn=&rft.btitle=&rft.title=Expert+Review+of+Vaccines&rft.issn=14760584&rft_id=info:doi/10.1586%2Ferv.12.148 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-11-01 N1 - Number of references - 1 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Vaccines; Rotavirus; Thailand, Chacoengsao Prov., Bangkok DO - http://dx.doi.org/10.1586/erv.12.148 ER - TY - JOUR T1 - Basic health condition of some rural small-scaled centralized water supplies in Dalian AN - 1352287741; 17962416 AB - Objective: To know the basic health condition of the rural small-scaled centralized water supplies in Dalian. Methods: Random sampling was used to investigate the hygienic status of the 16 rural small-scaled centralized water supply works. After investigation and data collection, a unified questionnaire was filled in. Results: Water resource was mainly from the deep groundwater, accounting for 62.50%; Water supply which mainly adopted the mode of high pool (tower) water supply, accounting for 56.25%; Hygienic license holding rate was 18.75%; The holding rate of health certificate was 56.00%; 68.75% of the water plants wasn't treated by purification and disinfection. Conclusion: There is a serious problem in disinfection of drinking water in rural areas. The hidden danger of health in drinking water may result in the outbreak of water-borne diseases and poisoning incidents. The control in rural environmental pollution should be strengthened and the water source should be protected. The health sector should participate in the checks acceptance. Thus the construction of water plant in the rural will well be carried out. Rural drinking water security funds should be implemented. Some comprehensive measures should be taken to inspect the management of drinking water in rural areas and water should be sterilized regularly. JF - Chinese Journal of Public Health Engineering / Zhongguo Weisheng Gongcheng Xue AU - Sun, Ya-Hui AU - Wang, Min AU - Xu, Zhen-Jie AD - Department of Environmental Hygiene, Dalian Center for Disease Control and Prevention, Dalian Liaoning 116021 Y1 - 2013/02// PY - 2013 DA - Feb 2013 SP - 50 EP - 51 PB - Editorial Board of Chinese Journal of Public Health Engineering, No. 3145, Jingyang Road Changchun 130062 Changchun 130062 China VL - 12 IS - 1 SN - 1671-4199, 1671-4199 KW - Health & Safety Science Abstracts; Pollution Abstracts KW - Disinfection KW - Water-borne diseases KW - China, People's Rep., Liaoning Prov., Dalian KW - H 3000:Environment and Ecology KW - P 2000:FRESHWATER POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1352287741?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chinese+Journal+of+Public+Health+Engineering+%2F+Zhongguo+Weisheng+Gongcheng+Xue&rft.atitle=Basic+health+condition+of+some+rural+small-scaled+centralized+water+supplies+in+Dalian&rft.au=Sun%2C+Ya-Hui%3BWang%2C+Min%3BXu%2C+Zhen-Jie&rft.aulast=Sun&rft.aufirst=Ya-Hui&rft.date=2013-02-01&rft.volume=12&rft.issue=1&rft.spage=50&rft.isbn=&rft.btitle=&rft.title=Chinese+Journal+of+Public+Health+Engineering+%2F+Zhongguo+Weisheng+Gongcheng+Xue&rft.issn=16714199&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-05-01 N1 - Last updated - 2014-03-10 N1 - SubjectsTermNotLitGenreText - Water-borne diseases; China, People's Rep., Liaoning Prov., Dalian ER - TY - JOUR T1 - Anti-tuberculosis treatment outcomes in HIV-infected adults exposed to isoniazid preventive therapy in Botswana AN - 1323800194; 17717089 AB - SETTING: Eight public health clinics in Gaborone and Francistown, Botswana. OBJECTIVES: To describe the characteristics and outcomes of incident tuberculosis (TB) cases in human immunodeficiency virus (HFV) infected adults exposed to isoniazid preventive therapy (IPT) with access to anti-retroviral and anti-tuberculosis treatment. DESIGN: In 1995 HIV-infected adults, TB disease was excluded before commencing IPT. During and after receipt of 6 or 36 months of IPT, symptomatic participants were evaluated using chest radiographs, sputum microscopy, cultures and drug susceptibility testing (DST). Incident TB cases received greater than or equal to 6 months of anti-tuberculosis treatment. RESULTS: Seventy-five incident TB cases were identified among 619 symptomatic participants. The median duration of IPT in these cases was 6 months (range 1-35), and the median time to initiation of anti-tuberculosis treatment was 12 months after IPT cessation. Antiretroviral therapy (ART) was initiated before anti-tuberculosis treatment in 37 cases. Culture was positive in 43/58 (74%) TB cultures. DST was available for 38 cases, of which six (16%) were resistant to isoniazid (INH); 67/75 (89%) cases, including four with INH-monoresistant TB, completed anti-tuberculosis treatment or were cured. CONCLUSIONS: With prompt initiation of anti-tuberculosis treatment and access to ART, excellent outcomes were achieved in a public health setting in HIV-infected adults who developed TB disease. JF - International Journal of Tuberculosis and Lung Disease AU - Sibanda, T AU - Tedla, Z AU - Nyirenda, S AU - Agizew, T AU - Marape, M AU - Miranda, A G AU - Reuter, H AU - Johnson, J L AU - Samandari, T AD - Division of Tuberculosis Elimination, CDC, 1600 Clifton Road NE, Mailstop E-45, Atlanta, GA 30333, USA, tts0@cdc.gov Y1 - 2013/02// PY - 2013 DA - Feb 2013 SP - 178 EP - 185 PB - International Union Against Tuberculosis and Lung Disease VL - 17 IS - 2 SN - 1027-3719, 1027-3719 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts; Microbiology Abstracts B: Bacteriology KW - Antiretroviral agents KW - Human immunodeficiency virus KW - Botswana KW - Tuberculosis KW - Public health KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - V 22360:AIDS and HIV KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1323800194?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Anti-tuberculosis+treatment+outcomes+in+HIV-infected+adults+exposed+to+isoniazid+preventive+therapy+in+Botswana&rft.au=Sibanda%2C+T%3BTedla%2C+Z%3BNyirenda%2C+S%3BAgizew%2C+T%3BMarape%2C+M%3BMiranda%2C+A+G%3BReuter%2C+H%3BJohnson%2C+J+L%3BSamandari%2C+T&rft.aulast=Sibanda&rft.aufirst=T&rft.date=2013-02-01&rft.volume=17&rft.issue=2&rft.spage=178&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-04-01 N1 - Last updated - 2014-03-10 N1 - SubjectsTermNotLitGenreText - Tuberculosis; Public health; Human immunodeficiency virus; Botswana ER - TY - JOUR T1 - A predictive model of Vibrio cholerae for combined temperature and organic nutrient in aquatic environments AN - 1285102034; 17628228 AB - The growth curves of V. cholerae NE-9 at different temperatures (range from 10 to 30 degree C) and chemical oxygen demand (COD) concentration (range from 5 to 40 mg l-1) were determined. The modified logistic model and Baranyi model were chosen to regress the growth curves. A new method for modelling effects of temperature and COD on the specific growth rate ( mu ) was successfully developed by a combination of modified square root-type equation and saturation growth rate model. The coefficient of determination (R2), bias factor (Bf) and accuracy factor (Af) were taken to assess the performance of the established model. Logistic model produced a good fit to the observed data (R2 = 0.952). However, the Baranyi model provided biologically plausible parameter estimates. The overall predictions for V. cholerae NE-9 growth agreed well with observed plate counts, and the average R2, Bf and Af values were 0.967, 1.198 and 1.201, respectively. The predicted model agreed well with observed data, and the result can be applied for the prediction of V. cholerae in actual environments. The results of this study provide the basis for the prediction of V. cholerae in sea water.Original Abstract: To develop a predictive model for Vibrio cholerae in sea water. JF - Journal of Applied Microbiology AU - Fu, S AU - Shen, J AU - Liu, Y AU - Chen, K AD - Nanchang Center for Disease Control and Prevention Y1 - 2013/02// PY - 2013 DA - February 2013 SP - 574 EP - 585 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 114 IS - 2 SN - 1364-5072, 1364-5072 KW - Microbiology Abstracts B: Bacteriology; ASFA 3: Aquatic Pollution & Environmental Quality; Oceanic Abstracts; ASFA 1: Biological Sciences & Living Resources; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Temperature effects KW - Growth rate KW - Prediction KW - Data processing KW - Mathematical models KW - Nutrients KW - Chemical oxygen demand KW - Aquatic environment KW - Models KW - Vibrio cholerae KW - Growth curves KW - Marine environment KW - Microbiology KW - Nutrients (mineral) KW - Abiotic factors KW - A 01450:Environmental Pollution & Waste Treatment KW - O 1090:Instruments/Methods KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms KW - J 02300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1285102034?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Microbiology&rft.atitle=A+predictive+model+of+Vibrio+cholerae+for+combined+temperature+and+organic+nutrient+in+aquatic+environments&rft.au=Fu%2C+S%3BShen%2C+J%3BLiu%2C+Y%3BChen%2C+K&rft.aulast=Fu&rft.aufirst=S&rft.date=2013-02-01&rft.volume=114&rft.issue=2&rft.spage=574&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Microbiology&rft.issn=13645072&rft_id=info:doi/10.1111%2Fjam.12058 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-01 N1 - Last updated - 2016-03-30 N1 - SubjectsTermNotLitGenreText - Prediction; Growth rate; Temperature effects; Mathematical models; Growth curves; Microbiology; Chemical oxygen demand; Nutrients (mineral); Abiotic factors; Data processing; Marine environment; Nutrients; Aquatic environment; Models; Vibrio cholerae DO - http://dx.doi.org/10.1111/jam.12058 ER - TY - JOUR T1 - Phylogenetic evidence for multiple and secondary introductions of invasive snails: Pomacea species in the People's Republic of China AN - 1272733573; 17564342 AB - To determine the genetic diversity of invasive snails (Pomacea spp.) that are implicated in crop damage, environmental degradation and human disease, and to determine their distribution pattern in a large part of eastern Asia. We collected Pomacea snails in a national survey using a grid sampling approach. Overall, 544 snails from 54 sites were used for the present investigation. The mitochondrial cox1 gene was amplified and sequenced from all the snails. We determined and classified the haplotypes using network analyses and mapped them within P.R. China. Haplotypes from this study, together with sequences available from GenBank, were used to reveal the global distribution of Pomacea canaliculata and P. insularum. We obtained 521 cox1 sequences and identified 24 unique haplotypes. Six haplotypes were commonly found in P.R. China. Two species, P. canaliculata and P. insularum, and one cryptic group were observed. The distribution of the 24 haplotypes across P.R. China shows a mosaic pattern. Globally, only six of 112 haplotypes of P. canaliculata, P. insularum, P. dolioides, P. lineata and P. paludosa are shared between introduced and native snail populations. We found 16 haplotype clusters, five of which occur in mainland P.R. China. Three of the five clusters could be traced back to South America. The remaining two clusters were unique to P.R. China. Phylogenetic analyses indicate that P. canaliculata, P. insularum and two cryptic groups, discovered by the present and previous studies, coexist in the mainland of P.R. China. The mosaic distribution and the high diversity found in the collection sites suggests multiple and secondary introductions. The findings indicate the importance of preventing further intentional introductions and call for appraisal of the risk posed by these snails in vulnerable areas. Discrimination of the ecological impacts of the different species or genotypes will help to develop setting-specific management strategies.Original Abstract: People's Republic of China (P.R. China). JF - Diversity and Distributions AU - Lv, Shan AU - Zhang, Yi AU - Liu, He-Xiang AU - Hu, Ling AU - Liu, Qin AU - Wei, Fu-Rong AU - Guo, Yun-Hai AU - Steinmann, Peter AU - Hu, Wei AU - Zhou, Xiao-Nong AU - Utzinger, Juerg AD - National Institute of Parasitic Diseases. Chinese Center for Disease Control and Prevention Y1 - 2013/02// PY - 2013 DA - Feb 2013 SP - 147 EP - 156 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 19 IS - 2 SN - 1366-9516, 1366-9516 KW - ASFA 1: Biological Sciences & Living Resources; Ecology Abstracts KW - Environmental degradation KW - Nucleotide sequence KW - Ecological distribution KW - Mitochondria KW - Genetic diversity KW - Genotypes KW - Crops KW - Evaluation KW - Population genetics KW - Haplotypes KW - Sampling KW - Vulnerability KW - Phylogenetics KW - Phylogeny KW - Pomacea canaliculata KW - Pomacea KW - Cyclooxygenase-1 KW - South America KW - Mosaics KW - China, People's Rep. KW - Introduced species KW - Evolution KW - Dispersion KW - D 04040:Ecosystem and Ecology Studies KW - Q1 08484:Species interactions: parasites and diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1272733573?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Diversity+and+Distributions&rft.atitle=Phylogenetic+evidence+for+multiple+and+secondary+introductions+of+invasive+snails%3A+Pomacea+species+in+the+People%27s+Republic+of+China&rft.au=Lv%2C+Shan%3BZhang%2C+Yi%3BLiu%2C+He-Xiang%3BHu%2C+Ling%3BLiu%2C+Qin%3BWei%2C+Fu-Rong%3BGuo%2C+Yun-Hai%3BSteinmann%2C+Peter%3BHu%2C+Wei%3BZhou%2C+Xiao-Nong%3BUtzinger%2C+Juerg&rft.aulast=Lv&rft.aufirst=Shan&rft.date=2013-02-01&rft.volume=19&rft.issue=2&rft.spage=147&rft.isbn=&rft.btitle=&rft.title=Diversity+and+Distributions&rft.issn=13669516&rft_id=info:doi/10.1111%2Fj.1472-4642.2012.00924.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-01-01 N1 - Last updated - 2014-09-18 N1 - SubjectsTermNotLitGenreText - Evaluation; Population genetics; Ecological distribution; Nucleotide sequence; Genetic diversity; Vulnerability; Introduced species; Phylogenetics; Dispersion; Environmental degradation; Phylogeny; Haplotypes; Mosaics; Mitochondria; Genotypes; Sampling; Crops; Evolution; Cyclooxygenase-1; Pomacea canaliculata; Pomacea; South America; China, People's Rep. DO - http://dx.doi.org/10.1111/j.1472-4642.2012.00924.x ER - TY - JOUR T1 - Patterns of condom use among students at historically Black colleges and universities: Implications for HIV prevention efforts among college-age young adults AN - 1272713256; 17528205 AB - Over 1.1 million Americans are living with human immunodeficiency virus (HIV), and African-American youth and young adults are disproportionately affected. Condoms are the most effective prevention tool, yet data regarding condom use patterns for African-American college youth are lacking. To inform and strengthen HIV prevention strategies with African-American college-age youth, we surveyed students attending 24 historically Black colleges and universities regarding condom use patterns. Students were administered anonymous questionnaires online to explore knowledge, attitudes, and practices related to condom use during last sexual intercourse (LSI). Among 824 sexually active respondents (51.8% female, median age 20 years, 90.6% heterosexuals), 526 (63.8%) reported condom use during LSI. Students who used condoms for disease prevention, whose mothers completed high school or had some college education or completed college were more likely to have used a condom during LSI. Spontaneity of sexual encounters, not feeling at risk of HIV, and partner-related perceptions were associated with condom non-use during LSI (p<0.05). Over a third of our college youth sample did not use a condom during LSI and may benefit from increased condom education efforts. These efforts should highlight condoms' effectiveness in protection from HIV. Future HIV education and prevention strategies with similar groups of young adults should explore the implications of maternal education, clarify perceptions of HIV risk, and consider strategies that increase consistent condom use to interrupt sexual transmission of HIV. JF - AIDS Care AU - El Bcheraoui, Charbel AU - Sutton, Madeline Y AU - Hardnett, Felicia P AU - Jones, Sandra B AD - Fulton County Health Services, Health and Wellness, Atlanta, GA, USA, igj4@cdc.gov Y1 - 2013/02/01/ PY - 2013 DA - 2013 Feb 01 SP - 186 EP - 193 PB - Taylor & Francis Group Ltd., 2 Park Square Oxford OX14 4RN United Kingdom VL - 25 IS - 2 SN - 0954-0121, 0954-0121 KW - Risk Abstracts; Virology & AIDS Abstracts KW - Age KW - Condoms KW - Human immunodeficiency virus KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1272713256?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+Care&rft.atitle=Patterns+of+condom+use+among+students+at+historically+Black+colleges+and+universities%3A+Implications+for+HIV+prevention+efforts+among+college-age+young+adults&rft.au=El+Bcheraoui%2C+Charbel%3BSutton%2C+Madeline+Y%3BHardnett%2C+Felicia+P%3BJones%2C+Sandra+B&rft.aulast=El+Bcheraoui&rft.aufirst=Charbel&rft.date=2013-02-01&rft.volume=25&rft.issue=2&rft.spage=186&rft.isbn=&rft.btitle=&rft.title=AIDS+Care&rft.issn=09540121&rft_id=info:doi/10.1080%2F09540121.2012.687864 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-01-01 N1 - Last updated - 2014-03-10 N1 - SubjectsTermNotLitGenreText - Condoms; Human immunodeficiency virus DO - http://dx.doi.org/10.1080/09540121.2012.687864 ER - TY - JOUR T1 - Properties of sediment NOM collected from a drinking water reservoir in south China, and its association with THMs and HAAs formation AN - 1312834418; 2013-023559 AB - The natural organic matter (NOM) from the sediment elutriate, which was obtained from a drinking water reservoir in South China, was fractionated into four fractions by using XAD-8 and XAD-4 resin. Dissolved organic carbon (DOC) as well as UV absorbance at 254 nm (UV (sub 254) ) and specific UV (sub 254) (SUV (sub 254) ) were used to quantify and characterize the NOM of raw sediment elutriate and the fractions. Formation of disinfection by-products (DBPs), i.e. trihalomethanes (THMs) and haloacetic acids (HAAs) were also investigated. Results showed that lots of organic matter can be liberated from the sediment during suspension. Hydrophilic organic matter (HiM) accounted for 50.7% of the DOC, followed by hydrophobic acid (HoA) (21.3%), transphilic organic matter (TPH) (15.2%) and other hydrophobic substances (HoS) (12.9%). Different from DOC distribution, the highest UV (sub 254) and SUV (sub 254) were detected in HoA, while the least were observed in HiM. All the organic fractions were good DBPs precursors. The hydrophobic fractions (HoS and HoA) were more important precursors of CHCl (sub 3) and TCAA as compared to other fractions, and UV (sub 254) was a good indicator for trichloroacetic acid (TCAA) formation. While for the hydrophilic fraction, relative higher dichloroacetic acid (DCAA) yields were observed, and DOC were good index for its formation. Abstract Copyright (2013) Elsevier, B.V. JF - Journal of Hydrology AU - Hong, H C AU - Huang, F Q AU - Wang, F Y AU - Ding, L X AU - Lin, H J AU - Liang, Y Y1 - 2013/01/07/ PY - 2013 DA - 2013 Jan 07 SP - 274 EP - 279 PB - Elsevier, Amsterdam VL - 476 SN - 0022-1694, 0022-1694 KW - water quality KW - methane KW - Far East KW - southern China KW - reservoirs KW - pollutants KW - statistical analysis KW - aliphatic hydrocarbons KW - pollution KW - trihalomethane KW - alkanes KW - hydrochemistry KW - environmental analysis KW - drinking water KW - organic acids KW - organic compounds KW - hydrocarbons KW - halocetic acid KW - chemical composition KW - Asia KW - water resources KW - water pollution KW - China KW - 02B:Hydrochemistry KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312834418?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Hydrology&rft.atitle=Properties+of+sediment+NOM+collected+from+a+drinking+water+reservoir+in+south+China%2C+and+its+association+with+THMs+and+HAAs+formation&rft.au=Hong%2C+H+C%3BHuang%2C+F+Q%3BWang%2C+F+Y%3BDing%2C+L+X%3BLin%2C+H+J%3BLiang%2C+Y&rft.aulast=Hong&rft.aufirst=H&rft.date=2013-01-07&rft.volume=476&rft.issue=&rft.spage=274&rft.isbn=&rft.btitle=&rft.title=Journal+of+Hydrology&rft.issn=00221694&rft_id=info:doi/10.1016%2Fj.jhydrol.2012.10.040 L2 - http://www.sciencedirect.com/science/journal/00221694 LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2013, American Geosciences Institute. Reference includes data from CAPCAS, Elsevier Scientific Publishers, Amsterdam, Netherlands N1 - Date revised - 2013-01-01 N1 - Number of references - 34 N1 - Document feature - illus. N1 - Last updated - 2013-07-18 N1 - CODEN - JHYDA7 N1 - SubjectsTermNotLitGenreText - aliphatic hydrocarbons; alkanes; Asia; chemical composition; China; drinking water; environmental analysis; Far East; halocetic acid; hydrocarbons; hydrochemistry; methane; organic compounds; organic acids; pollutants; pollution; reservoirs; southern China; statistical analysis; trihalomethane; water pollution; water quality; water resources DO - http://dx.doi.org/10.1016/j.jhydrol.2012.10.040 ER - TY - JOUR T1 - Theoretical relationship between vibration transmissibility and driving-point response functions of the human body AN - 1458532945; 18697876 AB - The relationship between the vibration transmissibility and driving-point response functions (DPRFs) of the human body is important for understanding vibration exposures of the system and for developing valid models. This study identified their theoretical relationship and demonstrated that the sum of the DPRFs can be expressed as a linear combination of the transmissibility functions of the individual mass elements distributed throughout the system. The relationship is verified using several human vibration models. This study also clarified the requirements for reliably quantifying transmissibility values used as references for calibrating the system models. As an example application, this study used the developed theory to perform a preliminary analysis of the method for calibrating models using both vibration transmissibility and DPRFs. The results of the analysis show that the combined method can theoretically result in a unique and valid solution of the model parameters, at least for linear systems. However, the validation of the method itself does not guarantee the validation of the calibrated model, because the validation of the calibration also depends on the model structure and the reliability and appropriate representation of the reference functions. The basic theory developed in this study is also applicable to the vibration analyses of other structures. JF - Journal of Sound and Vibration AU - Dong, R G AU - Welcome, DE AU - McDowell, T W AU - Wu, J Z AD - ECTB/HELD/NIOSH/CDC. 1095 Willowdale Road, MS L-2027, Morgantown, WV 26505, USA, rkd6@cdc.gov PY - 2013 SP - 6193 EP - 6202 PB - Elsevier B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 332 IS - 24 SN - 0022-460X, 0022-460X KW - Health & Safety Science Abstracts KW - Vibration KW - H 6000:Natural Disasters/Civil Defense/Emergency Management UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1458532945?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Sound+and+Vibration&rft.atitle=Theoretical+relationship+between+vibration+transmissibility+and+driving-point+response+functions+of+the+human+body&rft.au=Dong%2C+R+G%3BWelcome%2C+DE%3BMcDowell%2C+T+W%3BWu%2C+J+Z&rft.aulast=Dong&rft.aufirst=R&rft.date=2013-01-02&rft.volume=332&rft.issue=24&rft.spage=6193&rft.isbn=&rft.btitle=&rft.title=Journal+of+Sound+and+Vibration&rft.issn=0022460X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-11-01 N1 - Last updated - 2016-01-21 N1 - SubjectsTermNotLitGenreText - Vibration ER - TY - JOUR T1 - Nutrition in pregnancy and early childhood and associations with obesity in developing countries AN - 1837305635; 17423592 AB - Concerns about the increasing rates of obesity in developing countries have led many policy makers to question the impacts of maternal and early child nutrition on risk of later obesity. The purposes of the review are to summarise the studies on the associations between nutrition during pregnancy and infant feeding practices with later obesity from childhood through adulthood and to identify potential ways for preventing obesity in developing countries. As few studies were identified in developing countries, key studies in developed countries were included in the review. Poor prenatal dietary intakes of energy, protein and micronutrients were shown to be associated with increased risk of adult obesity in offspring. Female offspring seem to be more vulnerable than male offspring when their mothers receive insufficient energy during pregnancy. By influencing birthweight, optimal prenatal nutrition might reduce the risk of obesity in adults. While normal birthweights (2500-3999 g) were associated with higher body mass index (BMI) as adults, they generally were associated with higher fat-free mass and lower fat mass compared with low birthweights (<2500 g). Low birthweight was associated with higher risk of metabolic syndrome and central obesity in adults. Breastfeeding and timely introduction of complementary foods were shown to protect against obesity later in life in observational studies. High-protein intake during early childhood however was associated with higher body fat mass and obesity in adulthood. In developed countries, increased weight gain during the first 2 years of life was associated with a higher BMI in adulthood. However, recent studies in developing countries showed that higher BMI was more related to greater lean body mass than fat mass. It appears that increased length at 2 years of age was positively associated with height, weight and fat-free mass, and was only weakly associated with fat mass. The protective associations between breastfeeding and obesity may differ in developing countries compared to developed countries because many studies in developed countries used formula feeding as a control. Future research on the relationship between breastfeeding, timely introduction of complementary feeding or rapid weight gain and obesity are warranted in developing countries. The focus of interventions to reduce risk of obesity in later life in developing countries could include:improving maternal nutritional status during pregnancy to reduce low birthweight; enhancing breastfeeding (including durations of exclusive and total breastfeeding); timely introduction of high-quality complementary foods (containing micronutrients and essential fats) but not excessive in protein; further evidence is needed to understand the extent of weight gain and length gain during early childhood are related to body composition in later life. JF - Maternal and Child Nutrition AU - Yang, Zhenyu AU - Huffman, Sandra L AD - National Institute of Nutrition and Food Safety. Chinese Center for Disease Control and Prevention Y1 - 2013/01// PY - 2013 DA - January 2013 SP - 105 EP - 119 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 9 SN - 1740-8695, 1740-8695 KW - Physical Education Index KW - Obesity KW - Body mass KW - Diet (weight control) KW - Height KW - Breasts KW - Adults KW - Nutrition KW - Pregnancy KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1837305635?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Maternal+and+Child+Nutrition&rft.atitle=Nutrition+in+pregnancy+and+early+childhood+and+associations+with+obesity+in+developing+countries&rft.au=Yang%2C+Zhenyu%3BHuffman%2C+Sandra+L&rft.aulast=Yang&rft.aufirst=Zhenyu&rft.date=2013-01-01&rft.volume=9&rft.issue=&rft.spage=105&rft.isbn=&rft.btitle=&rft.title=Maternal+and+Child+Nutrition&rft.issn=17408695&rft_id=info:doi/10.1111%2Fmcn.12010 LA - English DB - Physical Education Index N1 - Date revised - 2016-11-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Obesity; Body mass; Diet (weight control); Height; Breasts; Adults; Nutrition; Pregnancy DO - http://dx.doi.org/10.1111/mcn.12010 ER - TY - JOUR T1 - Effects of Low-Temperature Flea Maintenance on the Transmission of Yersinia pestis by Oropsylla montana AN - 1668248871; PQ0001216807 AB - Yersinia pestis, the causative agent of plague, is primarily a rodent-associated, flea-borne zoonosis maintained in sylvatic foci throughout western North America. We examined whether holding fleas at subambient temperatures affected the transmissibility of Y. pestis by this vector. An infectious blood meal containing a virulent Y. pestis strain (CO96-3188) was given to colony-reared O. montana fleas. Potentially infected fleas were maintained at different temperatures (6 degree C, 10 degree C, 15 degree C, or 23 degree C). Mice were monitored for signs of infection for 21 days after exposure to infectious fleas. Fleas held at 6 degree C, 10 degree C, and 15 degree C were able to effectively transmit at every time point p.i. The percentage of transmission to naive mice by fleas maintained at low temperatures (46.0% at 6 degree C, 71.4% at 10 degree C, 66.7% at 15 degree C) was higher than for fleas maintained at 23 degree C (25.4%) and indicates that O. montana fleas efficiently transmit Y. pestis at low temperatures. JF - Vector Borne and Zoonotic Diseases AU - Williams, Shanna K AU - Schotthoefer, Anna M AU - Montenieri, John A AU - Holmes, Jennifer L AU - Vetter, Sara M AU - Gage, Kenneth L AU - Bearden, Scott W AD - Bacterial Diseases Branch, Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado PY - 2013 SP - 468 EP - 478 PB - Mary Ann Liebert, Inc., 2 Madison Ave Larchmont NY 10538-1962 United States VL - 13 IS - 7 SN - 1530-3667, 1530-3667 KW - Microbiology Abstracts B: Bacteriology; Entomology Abstracts KW - Yersinia pestis KW - Oropsylla montana KW - Low-temperature transmission KW - Plague KW - Temperature effects KW - Vectors KW - Blood meals KW - Infection KW - Disease transmission KW - J 02410:Animal Diseases KW - Z 05350:Medical, Veterinary, and Agricultural Entomology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1668248871?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vector+Borne+and+Zoonotic+Diseases&rft.atitle=Effects+of+Low-Temperature+Flea+Maintenance+on+the+Transmission+of+Yersinia+pestis+by+Oropsylla+montana&rft.au=Williams%2C+Shanna+K%3BSchotthoefer%2C+Anna+M%3BMontenieri%2C+John+A%3BHolmes%2C+Jennifer+L%3BVetter%2C+Sara+M%3BGage%2C+Kenneth+L%3BBearden%2C+Scott+W&rft.aulast=Williams&rft.aufirst=Shanna&rft.date=2013-01-01&rft.volume=13&rft.issue=7&rft.spage=468&rft.isbn=&rft.btitle=&rft.title=Vector+Borne+and+Zoonotic+Diseases&rft.issn=15303667&rft_id=info:doi/10.1089%2Fvbz.2012.1017 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Last updated - 2015-12-09 N1 - SubjectsTermNotLitGenreText - Temperature effects; Vectors; Plague; Blood meals; Infection; Disease transmission; Yersinia pestis DO - http://dx.doi.org/10.1089/vbz.2012.1017 ER - TY - JOUR T1 - Perceptions about the harm of secondhand smoke exposure among U.S. middle and high school students: findings from the 2012 National Youth Tobacco Survey AN - 1660408494; 18273282 AB - Background: Increased knowledge of the harmful effects of SHS is an evidence-based key indicator for eliminating nonsmokers' exposure to SHS. This study assessed the prevalence and predictors of perceptions about the harm of secondhand smoke (SHS) exposure among U.S. middle and high school students. Findings: Data were obtained from the 2012 National Youth Tobacco Survey, a nationally representative school-based survey of U.S. students in grades 6-12. Respondents who reported that they thought breathing smoke from other people's cigarettes or other tobacco products causes "some" or "a lot" of harm were considered to have the perception that SHS is harmful. Multivariate logistic regression was used to identify predictors of the perception that SHS is harmful. Predictors included sex, race/ethnicity, school grade level, current tobacco use, and whether the respondent currently lived with a tobacco user. Overall, 75.4% of students perceived SHS exposure as harmful. The adjusted odds of perceiving SHS exposure as harmful were higher among non-Hispanic Asians than among non-Hispanic whites, and among students in 10 super(th)-12 super(th) grades than among students in 8 super(th) grade. Adjusted odds were lower among boys than among girls, among non-Hispanic blacks than among non-Hispanic whites, among students living with a tobacco user than among those not, and among those who use combustible tobacco only or both combustible and non-combustible tobacco than among those who use no tobacco. Conclusions: Most middle and high school students perceive SHS exposure as harmful, but efforts are needed to increase the prevalence of this perception in certain subpopulations, particularly tobacco users. JF - Tobacco Induced Diseases AU - King, Brian A AU - Dube, Shanta R AU - Babb, Stephen D AD - Office on Smoking and Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway, MS K-79, Atlanta, GA 30341, USA Y1 - 2013 PY - 2013 DA - 2013 SP - 16 PB - International Society for the Prevention of Tobacco Induced Diseases, Postfach 185431 Essen D-45204 Germany VL - 11 IS - 1 SN - 1617-9625, 1617-9625 KW - Toxicology Abstracts KW - Tobacco KW - Tobacco smoke pollution KW - Adolescent KW - Perception KW - Risk KW - Students KW - Smoke KW - Data processing KW - Cigarettes KW - Respiration KW - Subpopulations KW - Ethnic groups KW - Races KW - Sex KW - X 24380:Social Poisons & Drug Abuse UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1660408494?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Tobacco+Induced+Diseases&rft.atitle=Perceptions+about+the+harm+of+secondhand+smoke+exposure+among+U.S.+middle+and+high+school+students%3A+findings+from+the+2012+National+Youth+Tobacco+Survey&rft.au=King%2C+Brian+A%3BDube%2C+Shanta+R%3BBabb%2C+Stephen+D&rft.aulast=King&rft.aufirst=Brian&rft.date=2013-01-01&rft.volume=11&rft.issue=1&rft.spage=16&rft.isbn=&rft.btitle=&rft.title=Tobacco+Induced+Diseases&rft.issn=16179625&rft_id=info:doi/10.1186%2F1617-9625-11-16 L2 - http://www.tobaccoinduceddiseases.com/content/11/1/16 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Number of references - 14 N1 - Last updated - 2015-03-04 N1 - SubjectsTermNotLitGenreText - Smoke; Data processing; Cigarettes; Perception; Subpopulations; Respiration; Tobacco; Races; Ethnic groups; Sex DO - http://dx.doi.org/10.1186/1617-9625-11-16 ER - TY - JOUR T1 - Vasoactive exposures during pregnancy and risk of microtia AN - 1660406119; 18483470 AB - BACKGROUND Little is known about the etiology of nonsyndromic microtia. This study investigated the hypothesis that microtia is caused by vascular disruption. METHODS The study analyzed data from the population-based National Birth Defects Prevention Study (NBDPS) for deliveries between 1997 and 2005. Four hundred eleven nonsyndromic cases of microtia, with or without additional defects, were compared to 6560 nonmalformed infants with respect to maternal exposures to vasoactive medications and smoking during the periconceptional period and conditions that have previously been associated with vascular events (multiple gestation, maternal history of type 1, type 2, or gestational diabetes, and hypertension). Odds ratios (ORs) were estimated with multivariable models, controlling for the effects of race/ethnicity, education, periconceptional folic acid use, and study center. RESULTS Risk estimates for vasoactive medications and smoking were not meaningfully increased. Maternal type 1/2 diabetes was diagnosed before or during the index pregnancy in 4% and 1% of cases, respectively, compared to 1% and 0.05% of controls; the adjusted OR for these two groups combined was 7.2 (95% confidence interval [CI], 3.9-13.1). Gestational diabetes was observed for 9% of cases and 6% of controls; the OR was moderately elevated (OR, 1.4; 95% CI, 0.9-2.0). ORs were also increased for multiple gestations (OR, 2.5; 95% CI, 1.5-4.2) and pre-existing hypertension (OR, 1.6; 95% CI, 1.0-2.5). CONCLUSIONS Because ORs were only elevated for diabetes and not for vasoactive exposures or other potential vascular events, findings suggest that some microtia occurrences may be part of the diabetic embryopathy rather than manifestations of vascular disruption. Birth Defects Research (Part A), 2013. [copy 2012 Wiley Periodicals, Inc. JF - Birth Defects Research Part A: Clinical and Molecular Teratology AU - Van Bennekom, Carla M AU - Mitchell, Allen A AU - Moore, Cynthia A AU - Werler, Martha M AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia., cvanben@bu.edu Y1 - 2013/01// PY - 2013 DA - Jan 2013 SP - 53 EP - 59 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 97 IS - 1 SN - 1542-0752, 1542-0752 KW - Toxicology Abstracts KW - birth defect KW - microtia KW - anotia KW - ear KW - epidemiology KW - diabetes mellitus KW - pregnancy KW - medication KW - Etiology KW - Data processing KW - Models KW - Pregnancy KW - Vasoactive agents KW - Microtia KW - Diabetes mellitus KW - Smoking KW - Gestation KW - Congenital defects KW - Folic acid KW - Ethnic groups KW - Races KW - Infants KW - Hypertension KW - X 24380:Social Poisons & Drug Abuse UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1660406119?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Birth+Defects+Research+Part+A%3A+Clinical+and+Molecular+Teratology&rft.atitle=Vasoactive+exposures+during+pregnancy+and+risk+of+microtia&rft.au=Van+Bennekom%2C+Carla+M%3BMitchell%2C+Allen+A%3BMoore%2C+Cynthia+A%3BWerler%2C+Martha+M&rft.aulast=Van+Bennekom&rft.aufirst=Carla&rft.date=2013-01-01&rft.volume=97&rft.issue=1&rft.spage=53&rft.isbn=&rft.btitle=&rft.title=Birth+Defects+Research+Part+A%3A+Clinical+and+Molecular+Teratology&rft.issn=15420752&rft_id=info:doi/10.1002%2Fbdra.23101 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-03-01 N1 - Last updated - 2015-03-04 N1 - SubjectsTermNotLitGenreText - Etiology; Data processing; Microtia; Vasoactive agents; Pregnancy; Models; Diabetes mellitus; Smoking; Gestation; Congenital defects; Folic acid; Races; Ethnic groups; Hypertension; Infants DO - http://dx.doi.org/10.1002/bdra.23101 ER - TY - JOUR T1 - Efficacy of Various Larvicides against Aedes aegypti Immatures in the Laboratory AN - 1618156251; 19845801 AB - We conducted a laboratory study to evaluate the efficacy of control agents against small larvae, large larvae, and pupae of Aedes aegypti to determine an appropriate larvicide regime to employ in emergency dengue control programs. The control agents included Bacillus thuringiensis var. israelensis (Bti), pyriproxyfen (an insect growth regulator), a larvicidal oil, Aquatain AMF (polydimethylsiloxane, a monomolecular film), and temephos at the recommend application dosages and rates. Our results showed that Bti, pyriproxyfen, and temephos were efficacious (100% mortality) against larvae, irrespective of the instar stage, but not against pupae of Ae. aegypti (1.5-7.8% mortality). Aquatain AMF, on the other hand, was very effective at controlling the pupal stage (100% mortality), but had limited efficacy against small larvae (38.0% mortality) and large larvae (78.0% mortality). The larvicidal oil was effective against all immature stages (93.3-100% mortality). Therefore, we concluded that for effectively interrupting the dengue transmission cycle, larvicides that kill the pupal stage (Aquatain AMF or larvicidal oil) should be included in an emergency dengue control program in addition to Bti, pyriproxyfen, or temephos. JF - Japanese Journal of Infectious Diseases AU - Wang, Chih-Yuan AU - Teng, Hwa-Jen AU - Lee, Si-Jia AU - Lin, Cheo AU - Wu, Jhy-Wen AU - Wu, Ho-Sheng AD - Research and Diagnostic Center, hjteng@cdc.gov.tw Y1 - 2013///0, PY - 2013 DA - 0, 2013 SP - 341 EP - 344 PB - National Institute of Infectious Diseases VL - 66 IS - 4 SN - 1344-6304, 1344-6304 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources KW - Aedes aegypti KW - Human diseases KW - Insect larvae KW - Bacillus thuringiensis KW - Pesticides KW - Larvae KW - Disease control KW - Pest control KW - Aquatic insects KW - Mortality causes KW - Public health KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1618156251?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Japanese+Journal+of+Infectious+Diseases&rft.atitle=Efficacy+of+Various+Larvicides+against+Aedes+aegypti+Immatures+in+the+Laboratory&rft.au=Wang%2C+Chih-Yuan%3BTeng%2C+Hwa-Jen%3BLee%2C+Si-Jia%3BLin%2C+Cheo%3BWu%2C+Jhy-Wen%3BWu%2C+Ho-Sheng&rft.aulast=Wang&rft.aufirst=Chih-Yuan&rft.date=2013-01-01&rft.volume=66&rft.issue=4&rft.spage=341&rft.isbn=&rft.btitle=&rft.title=Japanese+Journal+of+Infectious+Diseases&rft.issn=13446304&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-10-01 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Human diseases; Insect larvae; Pesticides; Disease control; Larvae; Pest control; Aquatic insects; Mortality causes; Public health; Aedes aegypti; Bacillus thuringiensis ER - TY - JOUR T1 - Phytoremediation of Heavy Metals Contamination in Sediments of Baihua Lake by Two Plants AN - 1524436599; 19759824 AB - A pot experiment was conducted to study the phytoremediation of Lolium multiflorum and Medicagosativa to heavy metals ( Cu, Zn, Cd) contamination in the sediments of Baihua Lake. Results: 1) the overground parts of the two plants accumulated less heavy metals than the underground parts, enrichment coefficient and transfer coefficient of the overground part were of the same order, Zn>Cd>Cu (L. multiflorum) and Cu>Cd>Zn(M. sativa), of which L. multiflorum was better than M. sativa. 2) The remediation effects of L. multiflorum and M. sativa were Cd > Zn > Cu and Cu > Cd > Zn respectively. JF - Guizhou Agricultural Sciences AU - GAO, Jing AU - LIANG, Longchao AU - CHEN, Zhuo AD - School of Chemistry and Material Science, Guizhou Normal University, Guiyang, Guizhou 550001; Guizhou Provincial Center for Disease Control and Prevention, Guiyang, Guizhou 550004, Chinai, gaojing1031@163.com PY - 2013 SP - 184 EP - 187 PB - Guizhou Sheng Nongye Kexueyuan, Jinzhuzhen Guiyang 550006 China VL - 41 IS - 9 SN - 1001-3601, 1001-3601 KW - Pollution Abstracts KW - phytoremediation KW - Lolium multi florum KW - Medicago sativa KW - heavy metals KW - sediments KW - Lakes KW - Bioremediation KW - Contamination KW - China, People's Rep., Guizhou Prov., Guiyang, Baihua L. KW - Lolium multiflorum KW - Heavy metals KW - Phytoremediation KW - Zinc KW - Cadmium KW - Copper KW - Sediments KW - P 2000:FRESHWATER POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1524436599?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Guizhou+Agricultural+Sciences&rft.atitle=Phytoremediation+of+Heavy+Metals+Contamination+in+Sediments+of+Baihua+Lake+by+Two+Plants&rft.au=GAO%2C+Jing%3BLIANG%2C+Longchao%3BCHEN%2C+Zhuo&rft.aulast=GAO&rft.aufirst=Jing&rft.date=2013-01-01&rft.volume=41&rft.issue=9&rft.spage=184&rft.isbn=&rft.btitle=&rft.title=Guizhou+Agricultural+Sciences&rft.issn=10013601&rft_id=info:doi/ LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-05-01 N1 - Last updated - 2015-12-23 N1 - SubjectsTermNotLitGenreText - Lakes; Bioremediation; Contamination; Phytoremediation; Heavy metals; Zinc; Cadmium; Copper; Sediments; Lolium multiflorum; China, People's Rep., Guizhou Prov., Guiyang, Baihua L. ER - TY - JOUR T1 - Typig of Vibrio parahaemolyticus by Repetitive Element Sequence-based PCR AN - 1505332898; 19006621 AB - Objective: REP-PCR method was used on typing research and genetic relationship research for Vibrio parahaemolyticus pathogens. Methods: REP sequences used as the PCR primers. Twenty Vibrio parahaemolyticus strains were amplified and DNA fingerprints were gained. The dendrograms were made by the computer software SPSS 11.5. And compared with serum typing. Results: According to REP-PCR fingerprints, 20 Vibrio parahaemolyticus strains could be grouped into 7 patterns by computer analysis and A type was predominant. Discriminative index was 0.932. Conclusion: REP-PCR is feasible for typing Vibrio parahaemolyticus strains. Vibrio parahaemolyticus strains, and indicate that the genetype of serovar 03 and 01 are closely related. JF - Chinese Journal of Microecology AU - Li, Xue AU - Ma, Jing-Hong AU - Zhao, Hong AU - Zhang, Xu AD - Liaoning Center for Disease Control and Prevention, Liaoning Shenyang 110005, 812626707@qq.com PY - 2013 SP - 1279 EP - 1281 PB - Editorial Department of Chinese Journal of Microecology, 465 Zhongshan Road Dalian 116027 China VL - 25 IS - 11 SN - 1005-376X, 1005-376X KW - Microbiology Abstracts B: Bacteriology KW - Genetic relationship KW - Computer programs KW - software KW - Typing KW - Vibrio parahaemolyticus KW - Computers KW - Polymerase chain reaction KW - Primers KW - Pathogens KW - Computer applications KW - J 02450:Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1505332898?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chinese+Journal+of+Microecology&rft.atitle=Typig+of+Vibrio+parahaemolyticus+by+Repetitive+Element+Sequence-based+PCR&rft.au=Li%2C+Xue%3BMa%2C+Jing-Hong%3BZhao%2C+Hong%3BZhang%2C+Xu&rft.aulast=Li&rft.aufirst=Xue&rft.date=2013-01-01&rft.volume=25&rft.issue=11&rft.spage=1279&rft.isbn=&rft.btitle=&rft.title=Chinese+Journal+of+Microecology&rft.issn=1005376X&rft_id=info:doi/ LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-03-01 N1 - Last updated - 2016-01-21 N1 - SubjectsTermNotLitGenreText - Genetic relationship; Computer programs; software; Typing; Computers; Polymerase chain reaction; Primers; Pathogens; Computer applications; Vibrio parahaemolyticus ER - TY - JOUR T1 - Trends in adult current asthma prevalence and contributing risk factors in the United States by state: 2000-2009 AN - 1492640574; 18960795 AB - Background: Current asthma prevalence among adults in the United States has reached historically high levels. Although national-level estimates indicate that asthma prevalence among adults increased by 33% from 2000 to 2009, state-specific temporal trends of current asthma prevalence and their contributing risk factors have not been explored. Methods: We used 2000-2009 Behavioral Risk Factor Surveillance System data from all 50 states and the District of Columbia (D.C.) to estimate state-specific current asthma prevalence by 2-year periods (2000-2001, 2002-2003, 2004-2005, 2006-2007, 2008-2009). We fitted a series of four logistic-regression models for each state to evaluate whether there was a statistically significant linear change in the current asthma prevalence over time, accounting for sociodemographic factors, smoking status, and weight status (using body mass index as the indicator). Results: During 2000-2009, current asthma prevalence increased in all 50 states and D.C., with significant increases in 46/50 (92%) states and D.C. After accounting for weight status in the model series with sociodemographic factors, and smoking status, 10 states (AR, AZ, IA, IL, KS, ME, MT, UT, WV, and WY) that had previously shown a significant increase did not show a significant increase in current asthma prevalence. Conclusions: There was a significant increasing trend in state-specific current asthma prevalence among adults from 2000 to 2009 in most states in the United States. Obesity prevalence appears to contribute to increased current asthma prevalence in some states. JF - BMC Public Health AU - Zhang, Xingyou AU - Morrison-Carpenter, Teresa AU - Holt, James B AU - Callahan, David B AD - Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway, Mailstop F78, Atlanta 30341, GA USA Y1 - 2013 PY - 2013 DA - 2013 SP - 1156 PB - BioMed Central Ltd., Middlesex House London W1T 4LB United Kingdom VL - 13 IS - 1 SN - 1471-2458, 1471-2458 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Smoking KW - Obesity KW - Historical account KW - USA KW - Risk factors KW - Body mass KW - Asthma KW - Respiratory diseases KW - R2 23060:Medical and environmental health KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1492640574?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=BMC+Public+Health&rft.atitle=Trends+in+adult+current+asthma+prevalence+and+contributing+risk+factors+in+the+United+States+by+state%3A+2000-2009&rft.au=Zhang%2C+Xingyou%3BMorrison-Carpenter%2C+Teresa%3BHolt%2C+James+B%3BCallahan%2C+David+B&rft.aulast=Zhang&rft.aufirst=Xingyou&rft.date=2013-01-01&rft.volume=13&rft.issue=1&rft.spage=1156&rft.isbn=&rft.btitle=&rft.title=BMC+Public+Health&rft.issn=14712458&rft_id=info:doi/10.1186%2F1471-2458-13-1156 L2 - http://www.biomedcentral.com/1471-2458/13/1156 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-01-01 N1 - Number of references - 68 N1 - Last updated - 2014-05-15 N1 - SubjectsTermNotLitGenreText - Historical account; Obesity; Smoking; Body mass; Risk factors; Asthma; Respiratory diseases; USA DO - http://dx.doi.org/10.1186/1471-2458-13-1156 ER - TY - JOUR T1 - Pulmonary function, chronic respiratory symptoms, and health-related quality of life among adults in the United States - National Health and Nutrition Examination Survey 2007-2010 AN - 1439228446; 18616087 AB - Background: We examined the association of impaired lung function and respiratory symptoms with measures of health status and health-related quality of life (HRQOL) among US adults. Methods: The sample included 5139 participants aged 40-79 years in the National Health and Nutrition Examination Survey 2007-2010 who underwent spirometric testing and responded to questions about respiratory symptoms, health status, and number of physically unhealthy, mentally unhealthy, or activity limitation days in the prior 30 days. Results: Among these adults, 7.2% had restrictive impairment (FEV sub(1)/FVC greater than or equal to 70%; FVC or =14 mentally unhealthy days), frequent physical distress (FPD; > or =14 physically unhealthy days), and frequent activity limitation (FAL; > or =14 activity limitation days) did not differ by lung function status. Adults who reported any respiratory symptoms (frequent cough, frequent phlegm, or past year wheeze) were more likely to report fair/poor health (PR = 1.5 [1.3-1.7]), FPD (PR = 1.6 [1.4-1.9]), FMD (PR = 1.8 [1.4-2.2]), and FAL (PR = 1.4 [1.1-1.9]) than those with no symptoms. Conclusions: These results suggest the importance of chronic respiratory symptoms as potential risk factors for poor HRQOL and suggest improved symptom treatment and prevention efforts would likely improve HRQOL. JF - BMC Public Health AU - Wheaton, Anne G AU - Ford, Earl S AU - Thompson, William W AU - Greenlund, Kurt J AU - Presley-Cantrell, Letitia R AU - Croft, Janet B AD - Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway, Mailstop K67, Atlanta, GA, 30341, USA Y1 - 2013 PY - 2013 DA - 2013 SP - 854 PB - BioMed Central Ltd., Middlesex House London W1T 4LB United Kingdom VL - 13 IS - 1 SN - 1471-2458, 1471-2458 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Smoking KW - USA KW - Prevention KW - Body mass KW - Risk factors KW - Respiratory function KW - Nutrition KW - Quality of life KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1439228446?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=BMC+Public+Health&rft.atitle=Pulmonary+function%2C+chronic+respiratory+symptoms%2C+and+health-related+quality+of+life+among+adults+in+the+United+States+-+National+Health+and+Nutrition+Examination+Survey+2007-2010&rft.au=Wheaton%2C+Anne+G%3BFord%2C+Earl+S%3BThompson%2C+William+W%3BGreenlund%2C+Kurt+J%3BPresley-Cantrell%2C+Letitia+R%3BCroft%2C+Janet+B&rft.aulast=Wheaton&rft.aufirst=Anne&rft.date=2013-01-01&rft.volume=13&rft.issue=1&rft.spage=854&rft.isbn=&rft.btitle=&rft.title=BMC+Public+Health&rft.issn=14712458&rft_id=info:doi/10.1186%2F1471-2458-13-854 L2 - http://www.biomedcentral.com/1471-2458/13/854 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-10-01 N1 - Number of references - 27 N1 - Last updated - 2013-10-21 N1 - SubjectsTermNotLitGenreText - Smoking; Prevention; Risk factors; Body mass; Respiratory function; Nutrition; Quality of life; USA DO - http://dx.doi.org/10.1186/1471-2458-13-854 ER - TY - JOUR T1 - Excess Frequent Insufficient Sleep in American Indians/Alaska Natives AN - 1434024016; 18541601 AB - Objective . Frequent insufficient sleep, defined as > or =14 days/past 30 days in which an adult did not get enough rest or sleep, is associated with adverse mental and physical health outcomes. Little is known about the prevalence of frequent insufficient sleep among American Indians/Alaska Natives (AI/AN). Methods . We assessed racial/ethnic differences in the prevalence of frequent insufficient sleep from the combined 2009-2010 Behavioral Risk Factor Surveillance Survey among 810,168 respondents who self-identified as non-Hispanic white (NHW, n=671,448 ), non-Hispanic black (NHB, n=67,685 ), Hispanic ( n=59,528 ), or AI/AN ( n=11,507 ). Results . We found significantly higher unadjusted prevalences (95% CI) of frequent insufficient sleep among AI/AN (34.2% [32.1-36.4]) compared to NHW (27.4% [27.1-27.6]). However, the age-adjusted excess prevalence of frequent insufficient sleep in AI/AN compared to NHW was decreased but remained significant with the addition of sex, education, and employment status; this latter relationship was further attenuated by the separate additions of obesity and lifestyle indicators, but was no longer significant with the addition of frequent mental distress to the model (PR = 1.05; 95% CI : 0.99-1.13). This is the first report of a high prevalence of frequent insufficient sleep among AI/AN. These results further suggest that investigation of sleep health interventions addressing frequent mental distress may benefit AI/AN populations. JF - Journal of Environmental and Public Health AU - Chapman, Daniel P AU - Croft, Janet B AU - Liu, Yong AU - Perry, Geraldine S AU - Presley-Cantrell, Letitia R AU - Ford, Earl S AD - Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Mailstop K-67, Atlanta, GA 30041, USA, dpc2@cdc.gov Y1 - 2013/01// PY - 2013 DA - Jan 2013 PB - Hindawi Publishing Corporation, P.O. Box 3079 Cuyahoga Falls OH 44223 United States VL - 2013 SN - 1687-9805, 1687-9805 KW - Risk Abstracts; Health & Safety Science Abstracts KW - USA, Alaska KW - Obesity KW - Education KW - Risk factors KW - Employment KW - Ethnic groups KW - Health promotion KW - R2 23060:Medical and environmental health KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1434024016?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+and+Public+Health&rft.atitle=Excess+Frequent+Insufficient+Sleep+in+American+Indians%2FAlaska+Natives&rft.au=Chapman%2C+Daniel+P%3BCroft%2C+Janet+B%3BLiu%2C+Yong%3BPerry%2C+Geraldine+S%3BPresley-Cantrell%2C+Letitia+R%3BFord%2C+Earl+S&rft.aulast=Chapman&rft.aufirst=Daniel&rft.date=2013-01-01&rft.volume=2013&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+and+Public+Health&rft.issn=16879805&rft_id=info:doi/10.1155%2F2013%2F259645 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-09-01 N1 - Number of references - 2 N1 - Last updated - 2014-10-02 N1 - SubjectsTermNotLitGenreText - Obesity; Education; Risk factors; Employment; Ethnic groups; Health promotion; USA, Alaska DO - http://dx.doi.org/10.1155/2013/259645 ER - TY - JOUR T1 - Analysis of monitoring data of iodine nutrition among population in Jiangxi province from 1995 to 2010 AN - 1430855809; 18438066 AB - Objective To master the level of iodine nutrition among population in Jiangxi province, and to provide a scientific basis for establishing the strategy for prevention and control of iodine deficiency disorders (IDD). Methods Retrospective method was adopted to analyze the goiter rate and frequency distribution of urinary iodine of children aged 8-10, the qualified rate of iodized salt, the coverage rate of iodized salt and the consumption rate of qualified iodized salt in residents of Jiangxi province from 1995 to 2010. The method of correlation analysis was used to analyze the relationship between goiter rate of children (by palpation) and the qualified rate of iodized salt, iodized salt coverage rate and residents consumption rate of qualified iodized salt. Results The goiter rates (measured by the method of palpation) of children aged 8-10 were down from 40.17% (482/1200) in 1995 to 0.80% (16/2000) in 2010 ( chi super(2) = 4.864, P < 0.05). The median of urinary iodine of children was higher than 200 mu g/L; the proportion of people whose urinary iodine content higher than 300 mu g/L was above 25.00% and the highest proportion was up to 58.01% (210/362) between 1995 - 2010. The minimum median of salt iodine was 17.77 mg/kg in 1995, and 29.30 - 39.10 mg/kg in other years. The qualified rates of iodized salt, the iodized salt coverage rates and the consumption rates of qualified iodized salt increased from 43.58% (452/1037), 86.42% (1037/1200) and 37.67% (452/1200) in 1995 to 97.95% (1916/1956), 99.95% (1956/1957) and 97.90% (1916/1957) in 2010, respectively; there was a growth trend over the years ( chi super(2) = 5.240, 6.118, 5.631, all P < 0.05). The goiter rates of children were related to the qualified rates of iodized salt, the iodized salt coverage rates and the consumption rates of qualified iodized salt, and the correlation coefficient (r) was - 0.833, - 0.881 and - 0.918 (all P < 0.05), respectively. Conclusions The level of iodine nutrition among residents in Jiangxi province has already gone beyond the appropriate level, and the iodine concentration in salt should be cut to ensure the appropriate iodine nutrition level among people. JF - Chinese Journal of Endemiology AU - Xiong, X-L AU - Liu, W AU - Li, Z-H AU - Wan, J-P AU - Qiu, H-Q AU - Chen, D AU - Shangguan, J AD - Institute of Endemic Disease, Jiangxi Center for Disease Control and Prevention, Nanchang 330029, jxlizhihong_88@126.com Y1 - 2013/01// PY - 2013 DA - Jan 2013 SP - 77 EP - 80 VL - 32 IS - 1 SN - 2095-4255, 2095-4255 KW - Ecology Abstracts KW - Salts KW - Goiter KW - Data processing KW - Iodine KW - Correlation analysis KW - Children KW - Nutrition KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1430855809?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chinese+Journal+of+Endemiology&rft.atitle=Analysis+of+monitoring+data+of+iodine+nutrition+among+population+in+Jiangxi+province+from+1995+to+2010&rft.au=Xiong%2C+X-L%3BLiu%2C+W%3BLi%2C+Z-H%3BWan%2C+J-P%3BQiu%2C+H-Q%3BChen%2C+D%3BShangguan%2C+J&rft.aulast=Xiong&rft.aufirst=X-L&rft.date=2013-01-01&rft.volume=32&rft.issue=1&rft.spage=77&rft.isbn=&rft.btitle=&rft.title=Chinese+Journal+of+Endemiology&rft.issn=20954255&rft_id=info:doi/10.3760%2Fcma.j.issn.2095-4255.2013.01.021 LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-09-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Salts; Goiter; Data processing; Iodine; Correlation analysis; Children; Nutrition DO - http://dx.doi.org/10.3760/cma.j.issn.2095-4255.2013.01.021 ER - TY - JOUR T1 - Nodding syndrome. AN - 1427746104; 23965548 AB - An epidemic illness characterized by head nodding associated with onchocerciasis has been described in eastern Africa since the early 1960s; we summarize published reports and recent studies. Onset of nodding occurs in previously healthy 5-15-year-old children and is often triggered by eating or cold temperatures and accompanied by cognitive impairment. Its incidence has increased in Uganda and South Sudan over the past 10 years. Four case-control studies identified modest and inconsistent associations. There were nonspecific lesions seen by magnetic resonance imaging, no cerebrospinal fluid inflammation, and markedly abnormal electroencephalography results. Nodding episodes are atonic seizures. Testing has failed to demonstrate associations with trypanosomiasis, cysticercosis, loiasis, lymphatic filariasis, cerebral malaria, measles, prion disease, or novel pathogens; or deficiencies of folate, cobalamin, pyridoxine, retinol, or zinc; or toxicity from mercury, copper, or homocysteine. There is a consistent enigmatic association with onchocerciasis detected by skin snip or serologic analysis. Nodding syndrome is an unexplained epidemic epilepsy. JF - Emerging infectious diseases AU - Dowell, Scott F AU - Sejvar, James J AU - Riek, Lul AU - Vandemaele, Katelijn A H AU - Lamunu, Margaret AU - Kuesel, Annette C AU - Schmutzhard, Erich AU - Matuja, William AU - Bunga, Sudhir AU - Foltz, Jennifer AU - Nutman, Thomas B AU - Winkler, Andrea S AU - Mbonye, Anthony K AD - Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. sfd2@cdc.gov Y1 - 2013 PY - 2013 DA - 2013 SP - 1374 EP - 1384 VL - 19 IS - 9 KW - Index Medicus KW - epilepsy KW - parasites KW - onchocerciasis KW - seizures KW - idiopathic KW - Africa KW - Uganda KW - South Sudan KW - Nodding syndrome KW - head nodding KW - epidemic KW - Magnetic Resonance Imaging KW - Young Adult KW - Age Factors KW - Africa -- epidemiology KW - Humans KW - Electroencephalography KW - Child KW - Geography, Medical KW - Child, Preschool KW - Infant KW - Adult KW - Case-Control Studies KW - Incidence KW - Adolescent KW - Male KW - Female KW - Nodding Syndrome -- diagnosis KW - Nodding Syndrome -- epidemiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1427746104?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Emerging+infectious+diseases&rft.atitle=Nodding+syndrome.&rft.au=Dowell%2C+Scott+F%3BSejvar%2C+James+J%3BRiek%2C+Lul%3BVandemaele%2C+Katelijn+A+H%3BLamunu%2C+Margaret%3BKuesel%2C+Annette+C%3BSchmutzhard%2C+Erich%3BMatuja%2C+William%3BBunga%2C+Sudhir%3BFoltz%2C+Jennifer%3BNutman%2C+Thomas+B%3BWinkler%2C+Andrea+S%3BMbonye%2C+Anthony+K&rft.aulast=Dowell&rft.aufirst=Scott&rft.date=2013-01-01&rft.volume=19&rft.issue=9&rft.spage=1374&rft.isbn=&rft.btitle=&rft.title=Emerging+infectious+diseases&rft.issn=1080-6059&rft_id=info:doi/10.3201%2Feid1909.130401 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2014-03-26 N1 - Date created - 2013-08-22 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Bull Soc Pathol Exot. 2000 Nov;93(4):255-9 [11204726] Afr Health Sci. 2012 Sep;12(3):242-8 [23382736] J Trop Pediatr. 2002 Aug;48(4):234-8 [12200986] AJNR Am J Neuroradiol. 2003 Sep;24(8):1560-9 [13679271] Lancet Neurol. 2003 Dec;2(12):714 [14649236] Epilepsia. 1979 Dec;20(6):613-22 [499114] Lancet. 1999 Jul 24;354(9175):306-7 [10440315] Autoimmunity. 2006 Feb;39(1):21-9 [16455579] Acta Neurol Taiwan. 2006 Mar;15(1):38-42 [16599284] J Child Neurol. 2007 May;22(5):550-4 [17690060] Am J Trop Med Hyg. 2008 Mar;78(3):400-1 [18337333] Lancet Infect Dis. 2008 May;8(5):310-22 [18471776] Ann Neurol. 2008 Jul;64(1):97-108 [18668637] Ann Trop Med Parasitol. 2008 Sep;102 Suppl 1:25-9 [18718151] Epilepsia. 2008 Dec;49(12):2008-15 [18503562] Am J Trop Med Hyg. 2009 Apr;80(4):619-24 [19346388] PLoS Negl Trop Dis. 2009;3(6):e461 [19529767] Vaccine. 2009 Oct 19;27(44):6186-95 [19815120] Chang Gung Med J. 2010 Jan-Feb;33(1):1-12 [20184790] Trop Doct. 2010 Jul;40(3):173-5 [20555049] Parasitology. 2010 Sep;137(10):1559-68 [20388236] N Engl J Med. 2010 Dec 23;363(26):2522-9 [21175314] Clin Exp Rheumatol. 2011 Jan-Feb;29(1):111-6 [21269582] Am J Trop Med Hyg. 2011 Aug;85(2):225-8 [21813839] West Afr J Med. 2011 Jan-Feb;30(1):62-5 [21863592] Mol Genet Metab. 2011 Sep-Oct;104(1-2):48-60 [21704546] BMJ. 2012;344:e349 [22246270] MMWR Morb Mortal Wkly Rep. 2012 Jan 27;61(3):52-4 [22278159] Lancet. 2012 Jan 28;379(9813):299 [22292160] Nat Med. 2012 Mar;18(3):334 [22395686] Arch Neurol. 2012 May;69(5):582-93 [22451162] Lancet Neurol. 2013 Feb;12(2):166-74 [23305742] Ann Trop Med Parasitol. 2002 Mar;96 Suppl 1:S29-39 [12081248] N1 - Last updated - 2017-01-19 DO - http://dx.doi.org/10.3201/eid1909.130401 ER - TY - JOUR T1 - Rice-eating pattern and the risk of metabolic syndrome especially waist circumference in Korean Genome and Epidemiology Study (KoGES) AN - 1399918082; 18172663 AB - Background: Metabolic syndrome poses a serious health threat in Asian countries. Rice is a staple food in Korea, and carbohydrate intake is associated with the risk of MetS. We hypothesized that various rice-eating patterns in a carbohydrate-based diet would have different effects on the risk of MetS. Methods: Participants were 26,006 subjects enrolled in the Korean Genome and Epidemiology Study between 2004 and 2006. They were classified into four dietary patterns - white rice, rice with beans, rice with multi-grains, and mixed based on their food frequency questionnaire responses. We compared metabolic risk traits according to the rice-eating patterns. Results: Nutrients consumption and the presence of MetS risk factors differed according to rice-eating patterns. In men odds ratio(OR) for central obesity was slightly elevated in mixed group(1.18). In women, the risk for central obesity and abnormal fasting glucose were lower in the rice with beans group (adjusted OR =0.79, 0.83 respectively) and central obesity in rice with multi-grains(adjusted OR=0.91) than the white rice group. In postmenopausal women, ORs for central obesity (0.78) and abnormal fasting glucose (0.75) in the rice with beans group and ORs for central obesity (0.83), abnormal HDL-cholesterol (0.87) and MetS(0.85) in the rice with multi-grains group was lower than those in white rice group. In premenopausal women, the risk for central obesity (OR=0.77) was reduced in the rice with beans group. Conclusion: The risk for MetS was lower in the rice with beans and rice with multi-grains groups compared with the white rice group, particularly in postmenopausal women. JF - BMC Public Health AU - Ahn, Younjhin AU - Park, Seon-Joo AU - Kwack, Hye-kyoung AU - Kim, Mi Kyung AU - Ko, Kwang-Pil AU - Kim, Sung Soo AD - Division of Epidemiology and Health Index, Center for Genome Science, National Institute of Health, Center for Disease Control and Prevention, Chungcheongbuk-do, South Korea Y1 - 2013 PY - 2013 DA - 2013 SP - 61 PB - BioMed Central Ltd., Middlesex House London W1T 4LB United Kingdom VL - 13 IS - 1 SN - 1471-2458, 1471-2458 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Diets KW - Obesity KW - Epidemiology KW - Post-menopause KW - Metabolic disorders KW - Risk factors KW - Glucose KW - Oryza sativa KW - Korea, Rep. KW - Carbohydrates KW - R2 23060:Medical and environmental health KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1399918082?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=BMC+Public+Health&rft.atitle=Rice-eating+pattern+and+the+risk+of+metabolic+syndrome+especially+waist+circumference+in+Korean+Genome+and+Epidemiology+Study+%28KoGES%29&rft.au=Ahn%2C+Younjhin%3BPark%2C+Seon-Joo%3BKwack%2C+Hye-kyoung%3BKim%2C+Mi+Kyung%3BKo%2C+Kwang-Pil%3BKim%2C+Sung+Soo&rft.aulast=Ahn&rft.aufirst=Younjhin&rft.date=2013-01-01&rft.volume=13&rft.issue=1&rft.spage=61&rft.isbn=&rft.btitle=&rft.title=BMC+Public+Health&rft.issn=14712458&rft_id=info:doi/10.1186%2F1471-2458-13-61 L2 - http://www.biomedcentral.com/1471-2458/13/61 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-07-01 N1 - Number of references - 39 N1 - Last updated - 2013-07-26 N1 - SubjectsTermNotLitGenreText - Diets; Obesity; Epidemiology; Post-menopause; Risk factors; Metabolic disorders; Glucose; Carbohydrates; Oryza sativa; Korea, Rep. DO - http://dx.doi.org/10.1186/1471-2458-13-61 ER - TY - JOUR T1 - Gestational Diabetes Mellitus and Postpartum Care Practices of Nurse-Midwives AN - 1364765675; 201309993 AB - Introduction: Postpartum screening for glucose intolerance among women with recent histories of gestational diabetes mellitus (GDM) is important for identifying women with continued glucose intolerance after birth, yet screening rates are suboptimal. In a thorough review of the literature, we found no studies of screening practices among certified nurse-midwives (CNMs). The objectives of our study were to estimate the prevalence of postpartum screening for abnormal glucose tolerance and related care by CNMs for women with recent histories of GDM and to identify strategies for improvement. Methods: From October through December 2010, the Ohio Department of Health sent a survey by mail and Internet to all licensed CNMs practicing in Ohio. We calculated prevalence estimates for knowledge, attitudes, clinical practices, and behaviors related to postpartum diabetes screening. Chi-square statistics were used to assess differences in self-reported clinical behaviors by frequency of postpartum screening. Results: Of the 146 CNMs who provided postpartum care and responded to the survey (62.2% response rate), 50.4% reported screening women with GDM-affected pregnancies for abnormal glucose tolerance at the postpartum visit. Of CNMs who screened postpartum, only 48.4% used fasting blood sugar or the 2-hour oral glucose tolerance test. Although 86.2% of all responding CNMs reported that they inform women with recent histories of GDM of their increased risk for type 2 diabetes mellitus, only 63.1% counseled these women to exercise regularly and 23.3% reported referring overweight/obese women to a diet support group or other nutrition counseling. CNMs reported that identification of community resources for lifestyle interventions and additional training in postpartum screening guidelines may help to improve postpartum care. Discussion: CNMs in Ohio reported suboptimal levels of postpartum diabetes testing and use of a recommended postpartum test. Providing CNMs with additional training and identifying community resources to support needed lifestyle behavior change may improve care for women with recent GDM-affected pregnancies. [Copyright Elsevier B.V.] JF - Journal of Midwifery & Women's Health AU - Ko, Jean Y AU - Dietz, Patricia M AU - Conrey, Elizabeth J AU - Rodgers, Loren AU - Shellhaas, Cynthia AU - Farr, Sherry L AU - Robbins, Cheryl L AD - Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA Y1 - 2013/01// PY - 2013 DA - January 2013 SP - 33 EP - 40 PB - John Wiley & Sons, Inc. VL - 58 IS - 1 SN - 1526-9523, 1526-9523 KW - gestational diabetes mellitus, glucose tolerance test, postpartum care, nurse-midwives, women's health KW - Screening KW - Tolerance KW - Postpartum women KW - Women KW - Glucose KW - Gestational diabetes mellitus KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1364765675?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Midwifery+%26+Women%27s+Health&rft.atitle=Gestational+Diabetes+Mellitus+and+Postpartum+Care+Practices+of+Nurse-Midwives&rft.au=Ko%2C+Jean+Y%3BDietz%2C+Patricia+M%3BConrey%2C+Elizabeth+J%3BRodgers%2C+Loren%3BShellhaas%2C+Cynthia%3BFarr%2C+Sherry+L%3BRobbins%2C+Cheryl+L&rft.aulast=Ko&rft.aufirst=Jean&rft.date=2013-01-01&rft.volume=58&rft.issue=1&rft.spage=33&rft.isbn=&rft.btitle=&rft.title=Journal+of+Midwifery+%26+Women%27s+Health&rft.issn=15269523&rft_id=info:doi/10.1111%2Fj.1542-2011.2012.00261.x LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2013-06-01 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Postpartum women; Screening; Women; Glucose; Tolerance; Gestational diabetes mellitus DO - http://dx.doi.org/10.1111/j.1542-2011.2012.00261.x ER - TY - JOUR T1 - Determination of four rodenticides in foods by gas chromatography-tandem mass spectrometry AN - 1323807601; 17755836 AB - A method was developed for determining four rodenticides fluoroacetamide, crimidine, tetramine and pindone in some foods matrices by GC-MS/MS. The drinking water and vinegar, soy sauce were extracted and cleanup using SPE and liquid-liquid extraction respectively. They were separated by an INNOWAX (30 m x 0.25 mm x 0.25 mu m) chromatographic column. The results showed that the method had good accuracy and precision, the recoveries and relative standard deviations(RSDs) of them were 57.2%~102.2% and 1.9%~9.5% in selected matrices; the minimum detection concentration of pindone was 2.0 mu g/L, and others were less than 0.5 mu g/L in water; the minimum detection concentration of pindone was 0.1 mg/kg, and others were less than 0.025 mg/kg in vinegar and soy sauce. The developed method was valid and provided the simultaneous confirmation and quantification of the four rodenticides in poisoning cases. JF - Chinese Journal of Analysis Laboratory AU - Rong, Wei-Guang AU - Liu, Hua-Liang AU - Chen, Bei AU - Zhu, Feng AU - Ji, Wen-Liang AU - Ma, Yong-Jian AD - Jiangsu Provincial Center for Disease Control, Nanjing 210009, rongweiguang@sohu.com Y1 - 2013/01// PY - 2013 DA - Jan 2013 SP - 73 EP - 77 PB - Fenxi Shiyanshi Editorial Board, No. 2 Beijing 100088 China VL - 32 IS - 1 SN - 1000-0720, 1000-0720 KW - Water Resources Abstracts; Aqualine Abstracts KW - Indexing in process UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1323807601?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chinese+Journal+of+Analysis+Laboratory&rft.atitle=Determination+of+four+rodenticides+in+foods+by+gas+chromatography-tandem+mass+spectrometry&rft.au=Rong%2C+Wei-Guang%3BLiu%2C+Hua-Liang%3BChen%2C+Bei%3BZhu%2C+Feng%3BJi%2C+Wen-Liang%3BMa%2C+Yong-Jian&rft.aulast=Rong&rft.aufirst=Wei-Guang&rft.date=2013-01-01&rft.volume=32&rft.issue=1&rft.spage=73&rft.isbn=&rft.btitle=&rft.title=Chinese+Journal+of+Analysis+Laboratory&rft.issn=10000720&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-04-01 N1 - Number of references - 6 N1 - Last updated - 2013-04-05 ER - TY - JOUR T1 - Accuracy of real-time PCR, Gram stain and culture for Streptococcus pneumoniae, Neisseria meningitidis and Haemophilus influenzae meningitis diagnosis AN - 1315608289; 17622695 AB - Background: Although cerebrospinal fluid (CSF) culture is the diagnostic reference standard for bacterial meningitis, its sensitivity is limited, particularly when antibiotics were previously administered. CSF Gram staining and real-time PCR are theoretically less affected by antibiotics; however, it is difficult to evaluate these tests with an imperfect reference standard. Methods and findings: CSF from patients with suspected meningitis from Salvador, Brazil were tested with culture, Gram stain, and real-time PCR using S. pneumoniae, N. meningitidis, and H. influenzae specific primers and probes. An antibiotic detection disk bioassay was used to test for the presence of antibiotic activity in CSF. The diagnostic accuracy of tests were evaluated using multiple methods, including direct evaluation of Gram stain and real-time PCR against CSF culture, evaluation of real-time PCR against a composite reference standard, and latent class analysis modeling to evaluate all three tests simultaneously. Results: Among 451 CSF specimens, 80 (17.7%) had culture isolation of one of the three pathogens (40 S. pneumoniae, 36 N. meningitidis, and 4 H. influenzae), and 113 (25.1%) were real-time PCR positive (51 S. pneumoniae, 57 N. meningitidis, and 5 H. influenzae). Compared to culture, real-time PCR sensitivity and specificity were 95.0% and 90.0%, respectively. In a latent class analysis model, the sensitivity and specificity estimates were: culture, 81.3% and 99.7%; Gram stain, 98.2% and 98.7%; and real-time PCR, 95.7% and 94.3%, respectively. Gram stain and real-time PCR sensitivity did not change significantly when there was antibiotic activity in the CSF. Conclusion: Real-time PCR and Gram stain were highly accurate in diagnosing meningitis caused by S. pneumoniae, N. meningitidis, and H. influenzae, though there were few cases of H. influenzae. Furthermore, real-time PCR and Gram staining were less affected by antibiotic presence and might be useful when antibiotics were previously administered. Gram staining, which is inexpensive and commonly available, should be encouraged in all clinical settings. JF - BMC Infectious Diseases AU - Wu, Henry M AU - Cordeiro, Soraia M AU - Harcourt, Brian H AU - Carvalho, MariadaGloriaS AU - Azevedo, Jailton AU - Oliveira, Tainara Q AU - Leite, Mariela C AU - Salgado, Katia AU - Reis, Mitermayer G AU - Plikaytis, Brian D AU - Clark, Thomas A AU - Mayer, Leonard W AU - Ko, Albert I AU - Martin, Stacey W AU - Reis, Joice N AD - Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, CDC, 1600 Clifton Road, Atlanta, GA, 30333, USA Y1 - 2013 PY - 2013 DA - 2013 SP - 26 PB - BioMed Central Ltd., Middlesex House London W1T 4LB United Kingdom VL - 13 IS - 1 KW - Microbiology Abstracts B: Bacteriology KW - Antibiotics KW - Haemophilus influenzae KW - Polymerase chain reaction KW - J:02400 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1315608289?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=BMC+Infectious+Diseases&rft.atitle=Accuracy+of+real-time+PCR%2C+Gram+stain+and+culture+for+Streptococcus+pneumoniae%2C+Neisseria+meningitidis+and+Haemophilus+influenzae+meningitis+diagnosis&rft.au=Wu%2C+Henry+M%3BCordeiro%2C+Soraia+M%3BHarcourt%2C+Brian+H%3BCarvalho%2C+MariadaGloriaS%3BAzevedo%2C+Jailton%3BOliveira%2C+Tainara+Q%3BLeite%2C+Mariela+C%3BSalgado%2C+Katia%3BReis%2C+Mitermayer+G%3BPlikaytis%2C+Brian+D%3BClark%2C+Thomas+A%3BMayer%2C+Leonard+W%3BKo%2C+Albert+I%3BMartin%2C+Stacey+W%3BReis%2C+Joice+N&rft.aulast=Wu&rft.aufirst=Henry&rft.date=2013-01-01&rft.volume=13&rft.issue=1&rft.spage=26&rft.isbn=&rft.btitle=&rft.title=BMC+Infectious+Diseases&rft.issn=1471-2334&rft_id=info:doi/10.1186%2F1471-2334-13-26 L2 - http://www.biomedcentral.com/1471-2334/13/26 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-03-01 N1 - Number of references - 1 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Polymerase chain reaction; Haemophilus influenzae DO - http://dx.doi.org/10.1186/1471-2334-13-26 ER - TY - JOUR T1 - Immunotoxicity and allergic potential induced by topical application of dimethyl carbonate (DMC) in a murine model. AN - 1312173792; 22953780 AB - Dimethyl carbonate (DMC) is an industrial chemical, used as a paint and adhesive solvent, with the potential for significant increases in production. Using select immune function assays, the purpose of these studies was to evaluate the immunotoxicity of DMC following dermal exposure using a murine model. Following a 28-day exposure, DMC produced a significant decrease in thymus weight at concentrations of 75% and greater. No effects on body weight, hematological parameters (erythrocytes, leukocytes, and their differentials), or immune cell phenotyping (B-cells, T-cells, and T-cell sub-sets) were identified. The IgM antibody response to sheep red blood cell (SRBC) was significantly reduced in the spleen but not the serum. DMC was not identified to be an irritant and evaluation of the sensitization potential, conducted using the local lymph node assay (LLNA) at concentrations ranging from 50-100%, did not identify increases in lymphocyte proliferation. These results demonstrate that dermal exposure to DMC induces immune suppression in a murine model and raise concern about potential human exposure and the need for occupational exposure regulations. JF - Journal of immunotoxicology AU - Anderson, Stacey E AU - Franko, Jennifer AU - Anderson, Katie L AU - Munson, Albert E AU - Lukomska, Ewa AU - Meade, B Jean AD - National Institute for Occupational Safety and Health-NIOSH, 1095 Willowdale Drive, Morgantown, WV 26505, USA. sanderson4@cdc.gov PY - 2013 SP - 59 EP - 66 VL - 10 IS - 1 KW - Formates KW - 0 KW - methyl carbonate KW - KE9J097SPN KW - Index Medicus KW - Cell Proliferation -- drug effects KW - Animals KW - Cells, Cultured KW - Humans KW - Disease Models, Animal KW - Mice KW - Mice, Inbred BALB C KW - Female KW - Antibody Formation -- drug effects KW - Organ Size -- drug effects KW - Immunosuppression KW - Occupational Exposure KW - Formates -- toxicity KW - Dermatitis, Contact -- immunology KW - Thymus Gland -- pathology KW - Formates -- administration & dosage KW - Thymus Gland -- drug effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312173792?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+immunotoxicology&rft.atitle=Immunotoxicity+and+allergic+potential+induced+by+topical+application+of+dimethyl+carbonate+%28DMC%29+in+a+murine+model.&rft.au=Anderson%2C+Stacey+E%3BFranko%2C+Jennifer%3BAnderson%2C+Katie+L%3BMunson%2C+Albert+E%3BLukomska%2C+Ewa%3BMeade%2C+B+Jean&rft.aulast=Anderson&rft.aufirst=Stacey&rft.date=2013-01-01&rft.volume=10&rft.issue=1&rft.spage=59&rft.isbn=&rft.btitle=&rft.title=Journal+of+immunotoxicology&rft.issn=1547-6901&rft_id=info:doi/10.3109%2F1547691X.2012.691124 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2013-09-04 N1 - Date created - 2013-02-22 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Toxicology. 2000 May 5;146(2-3):221-7 [10814854] Toxicology. 2000 Dec 7;156(1):1-11 [11162871] Chemosphere. 2001 Apr;43(1):115-21 [11233818] Food Chem Toxicol. 2001 Aug;39(8):877-86 [11434995] Toxicol Sci. 2003 Sep;75(1):89-98 [12832659] Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2002 Oct;20(5):362-4 [14694727] Regul Toxicol Pharmacol. 2004 Oct;40(2):168-76 [15450719] Arch Toxicol. 1990;64(4):320-8 [2143647] Fundam Appl Toxicol. 1992 Feb;18(2):200-10 [1534777] Toxicol Lett. 1992 Dec;64-65 Spec No:71-8 [1471226] Teratology. 1993 Mar;47(3):175-88 [8475461] Fundam Appl Toxicol. 1993 Nov;21(4):412-9 [8253294] Toxicol Sci. 1999 Apr;48(2):206-17 [10353312] Science. 1963 Apr 26;140(3565):405 [13957684] J Chromatogr A. 2005 Feb 18;1065(2):257-64 [15782972] Am J Ind Med. 2006 Dec;49(12):1046-55 [17036363] J Appl Toxicol. 2007 Jan-Feb;27(1):32-42 [17177173] Toxicol Sci. 2007 Jun;97(2):355-63 [17347135] ChemSusChem. 2008;1(10):813-6 [18792036] J Hazard Mater. 2009 Jan 30;161(2-3):1193-201 [18513858] Chem Commun (Camb). 2012 Mar 18;48(23):2912-4 [22301882] Environ Res. 1989 Jun;49(1):93-103 [2785914] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.3109/1547691X.2012.691124 ER - TY - JOUR T1 - Association between perceived insufficient sleep, frequent mental distress, obesity and chronic diseases among US adults, 2009 behavioral risk factor surveillance system AN - 1291612962; 17648570 AB - Background: Although evidence suggests that poor sleep is associated with chronic disease, little research has been conducted to assess the relationships between insufficient sleep, frequent mental distress (FMD > or =14 days during the past 30 days), obesity, and chronic disease including diabetes mellitus, coronary heart disease, stroke, high blood pressure, asthma, and arthritis. Methods: Data from 375,653 US adults aged greater than or equal to 18 years in the 2009 Behavioral Risk Factor Surveillance System were used to assess the relationships between insufficient sleep and chronic disease. The relationships were further examined using a multivariate logistic regression model after controlling for age, sex, race/ethnicity, education, and potential mediators (FMD and obesity). Results: The overall prevalence of insufficient sleep during the past 30 days was 10.4% for all 30 days, 17.0% for 14-29 days, 42.0% for 1-13 days, and 30.6% for zero day. The positive relationships between insufficient sleep and each of the six chronic disease were significant (p < 0.0001) after adjustment for covariates and were modestly attenuated but not fully explained by FMD. The relationships between insufficient sleep and both diabetes and high blood pressure were also modestly attenuated but not fully explained by obesity. Conclusions: Assessment of sleep quantity and quality and additional efforts to encourage optimal sleep and sleep health should be considered in routine medical examinations. Ongoing research designed to test treatments for obesity, mental distress, or various chronic diseases should also consider assessing the impact of these treatments on sleep health. JF - BMC Public Health AU - Liu, Yong AU - Croft, Janet B AU - Wheaton, Anne G AU - Perry, Geraldine S AU - Chapman, Daniel P AU - Strine, Tara W AU - McKnight-Eily, Lela R AU - Presley-Cantrell, Letitia AD - Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention (CDC), 4770 Buford Highway, NE, Mail-Stop K-67, Atlanta, GA, 30341, USA Y1 - 2013 PY - 2013 DA - 2013 SP - 84 PB - BioMed Central Ltd., Middlesex House London W1T 4LB United Kingdom VL - 13 IS - 1 SN - 1471-2458, 1471-2458 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Cardiovascular diseases KW - Education KW - Ethnic groups KW - Hypertension KW - Obesity KW - Perception KW - Respiratory diseases KW - Risk factors KW - Stroke KW - USA KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1291612962?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=BMC+Public+Health&rft.atitle=Association+between+perceived+insufficient+sleep%2C+frequent+mental+distress%2C+obesity+and+chronic+diseases+among+US+adults%2C+2009+behavioral+risk+factor+surveillance+system&rft.au=Liu%2C+Yong%3BCroft%2C+Janet+B%3BWheaton%2C+Anne+G%3BPerry%2C+Geraldine+S%3BChapman%2C+Daniel+P%3BStrine%2C+Tara+W%3BMcKnight-Eily%2C+Lela+R%3BPresley-Cantrell%2C+Letitia&rft.aulast=Liu&rft.aufirst=Yong&rft.date=2013-01-01&rft.volume=13&rft.issue=1&rft.spage=84&rft.isbn=&rft.btitle=&rft.title=BMC+Public+Health&rft.issn=14712458&rft_id=info:doi/10.1186%2F1471-2458-13-84 L2 - http://www.biomedcentral.com/1471-2458/13/84 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-01 N1 - Number of references - 53 N1 - Last updated - 2013-03-11 N1 - SubjectsTermNotLitGenreText - Obesity; Education; Perception; Risk factors; Stroke; Cardiovascular diseases; Respiratory diseases; Ethnic groups; Hypertension; USA DO - http://dx.doi.org/10.1186/1471-2458-13-84 ER - TY - JOUR T1 - Adverse childhood experiences and frequent insufficient sleep in 5 U.S. States, 2009: a retrospective cohort study AN - 1285099925; 17620679 AB - Background: Although adverse childhood experiences (ACEs) have previously been demonstrated to be adversely associated with a variety of health outcomes in adulthood, their specific association with sleep among adults has not been examined. To better address this issue, this study examines the relationship between eight self-reported ACEs and frequent insufficient sleep among community-dwelling adults residing in 5 U.S. states in 2009. Methods: To assess whether ACEs were associated with frequent insufficient sleep (respondent did not get sufficient rest or sleep > or =14 days in past 30 days) in adulthood, we analyzed ACE data collected in the 2009 Behavioral Risk Factor Surveillance System, a random-digit-dialed telephone survey in Arkansas, Louisiana, New Mexico, Tennessee, and Washington. ACEs included physical abuse, sexual abuse, verbal abuse, household mental illness, incarcerated household members, household substance abuse, parental separation/divorce, and witnessing domestic violence before age 18. Smoking status and frequent mental distress (FMD) (> or =14 days in past 30 days when self-perceived mental health was not good) were assessed as potential mediators in multivariate logistic regression analyses of frequent insufficient sleep by ACEs adjusted for race/ethnicity, gender, education, and body mass index. Results: Overall, 28.8% of 25,810 respondents reported frequent insufficient sleep, 18.8% were current smokers, 10.8% reported frequent mental distress, 59.5% percent reported > or =1 ACE, and 8.7% reported > or = 5 ACEs. Each ACE was associated with frequent insufficient sleep in multivariate analyses. Odds of frequent insufficient sleep were 2.5 (95% CI, 2.1-3.1) times higher in persons with > or =5 ACEs compared to those with no ACEs. Most relationships were modestly attenuated by smoking and FMD, but remained significant. Conclusions: Childhood exposures to eight indicators of child maltreatment and household dysfunction were significantly associated with frequent insufficient sleep during adulthood in this population. ACEs could be potential indicators promoting further investigation of sleep insufficiency, along with consideration of FMD and smoking. JF - BMC Public Health AU - Chapman, Daniel P AU - Liu, Yong AU - Presley-Cantrell, Letitia R AU - Edwards, Valerie J AU - Wheaton, Anne G AU - Perry, Geraldine S AU - Croft, Janet B AD - Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Mailstop K-67, Atlanta, GA, 30041, USA Y1 - 2013 PY - 2013 DA - 2013 SP - 3 PB - BioMed Central Ltd., Middlesex House London W1T 4LB United Kingdom VL - 13 IS - 1 SN - 1471-2458, 1471-2458 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Child abuse KW - Children KW - Education KW - Households KW - Mental disorders KW - Sexual assault KW - Sleep KW - Smoking KW - Substance abuse KW - USA, Washington KW - USA, Louisiana KW - USA, New Mexico KW - USA, Tennessee KW - USA, Arkansas KW - R2 23110:Psychological aspects KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1285099925?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=BMC+Public+Health&rft.atitle=Adverse+childhood+experiences+and+frequent+insufficient+sleep+in+5+U.S.+States%2C+2009%3A+a+retrospective+cohort+study&rft.au=Chapman%2C+Daniel+P%3BLiu%2C+Yong%3BPresley-Cantrell%2C+Letitia+R%3BEdwards%2C+Valerie+J%3BWheaton%2C+Anne+G%3BPerry%2C+Geraldine+S%3BCroft%2C+Janet+B&rft.aulast=Chapman&rft.aufirst=Daniel&rft.date=2013-01-01&rft.volume=13&rft.issue=1&rft.spage=3&rft.isbn=&rft.btitle=&rft.title=BMC+Public+Health&rft.issn=14712458&rft_id=info:doi/10.1186%2F1471-2458-13-3 L2 - http://www.biomedcentral.com/1471-2458/13/3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-01 N1 - Number of references - 38 N1 - Last updated - 2013-03-11 N1 - SubjectsTermNotLitGenreText - Smoking; Education; Mental disorders; Households; Sleep; Child abuse; Sexual assault; Children; Substance abuse; USA, Washington; USA, Tennessee; USA, New Mexico; USA, Louisiana; USA, Arkansas DO - http://dx.doi.org/10.1186/1471-2458-13-3 ER - TY - JOUR T1 - National surveillance for radiological exposures and intentional potassium iodide and iodine product ingestions in the United States associated with the 2011 Japan radiological incident. AN - 1273497369; 23043524 AB - In March of 2011, an earthquake struck Japan causing a tsunami that resulted in a radiological release from the damaged Fukushima Daiichi nuclear power plant. Surveillance for potential radiological and any iodine/iodide product exposures was initiated on the National Poison Data System (NPDS) to target public health messaging needs within the United States (US). Our objectives are to describe self-reported exposures to radiation, potassium iodide (KI) and other iodine/iodide products which occurred during the US federal response and discuss its public health impact. All calls to poison centers associated with the Japan incident were identified from March 11, 2011 to April 18, 2011 in NPDS. Exposure, demographic and health outcome information were collected. Calls about reported radiation exposures and KI or other iodine/iodide product ingestions were then categorized with regard to exposure likelihood based on follow-up information obtained from the PC where each call originated. Reported exposures were subsequently classified as probable exposures (high likelihood of exposure), probable non-exposures (low likelihood of exposure), and suspect exposure (unknown likelihood of exposure). We identified 400 calls to PCs associated with the incident, with 340 information requests (no exposure reported) and 60 reported exposures. The majority (n = 194; 57%) of the information requests mentioned one or more substances. Radiation was inquired about most frequently (n = 88; 45%), followed by KI (n = 86; 44%) and other iodine/iodide products (n = 47; 24%). Of the 60 reported exposures, KI was reported most frequently (n = 25; 42%), followed by radiation (n = 22; 37%) and other iodine/iodide products (n = 13; 22%). Among reported KI exposures, most were classified as probable exposures (n = 24; 96%); one was a probable non-exposure. Among reported other iodine/iodide product exposures, most were probable exposures (n = 10, 77%) and the rest were suspect exposures (n = 3; 23%). The reported radiation exposures were classified as suspect exposures (n = 16, 73%) or probable non-exposures (n = 6; 27%). No radiation exposures were classified as probable exposures. A small number of the probable exposures to KI and other iodide/iodine products reported adverse signs or symptoms (n = 9; 26%). The majority of probable exposures had no adverse outcomes (n = 28; 82%). These data identified a potential public health information gap regarding KI and other iodine/iodide products which was then addressed through public health messaging activities. During the Japan incident response, surveillance activities using NPDS identified KI and other iodine/iodide products as potential public health concerns within the US, which guided CDC's public health messaging and communication activities. Regional PCs can provide timely and additional information during a public health emergency to enhance data collected from surveillance activities, which in turn can be used to inform public health decision-making. JF - Clinical toxicology (Philadelphia, Pa.) AU - Law, Royal K AU - Schier, Josh G AU - Martin, Colleen A AU - Olivares, Dagny E AU - Thomas, Richard G AU - Bronstein, Alvin C AU - Chang, Arthur S AD - National Center for Environmental Health/Agency for Toxic Substances and Disease Registry, CDC, Atlanta, GA 30341, USA. Rlaw@cdc.gov Y1 - 2013/01// PY - 2013 DA - January 2013 SP - 41 EP - 46 VL - 51 IS - 1 KW - Iodides KW - 0 KW - Potassium Iodide KW - 1C4QK22F9J KW - Iodine KW - 9679TC07X4 KW - Abridged Index Medicus KW - Index Medicus KW - United States KW - Self Report KW - Patient Acceptance of Health Care KW - Centers for Disease Control and Prevention (U.S.) KW - Humans KW - Environmental Exposure KW - Follow-Up Studies KW - Poison Control Centers KW - Male KW - Female KW - Population Surveillance KW - Health Promotion KW - Radiation Dosage KW - Potassium Iodide -- toxicity KW - Fukushima Nuclear Accident KW - Iodine -- toxicity KW - Radiation Effects KW - Iodides -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1273497369?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+toxicology+%28Philadelphia%2C+Pa.%29&rft.atitle=National+surveillance+for+radiological+exposures+and+intentional+potassium+iodide+and+iodine+product+ingestions+in+the+United+States+associated+with+the+2011+Japan+radiological+incident.&rft.au=Law%2C+Royal+K%3BSchier%2C+Josh+G%3BMartin%2C+Colleen+A%3BOlivares%2C+Dagny+E%3BThomas%2C+Richard+G%3BBronstein%2C+Alvin+C%3BChang%2C+Arthur+S&rft.aulast=Law&rft.aufirst=Royal&rft.date=2013-01-01&rft.volume=51&rft.issue=1&rft.spage=41&rft.isbn=&rft.btitle=&rft.title=Clinical+toxicology+%28Philadelphia%2C+Pa.%29&rft.issn=1556-9519&rft_id=info:doi/10.3109%2F15563650.2012.732701 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2013-03-07 N1 - Date created - 2013-01-14 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Ann Emerg Med. 2006 Feb;47(2):170-6 [16431230] Ann Emerg Med. 2012 Jan;59(1):56-61 [21937144] Am J Med. 1993 May;94(5):524-32 [8498398] Comment In: Clin Toxicol (Phila). 2013 Jul;51(6):521 [23697456] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.3109/15563650.2012.732701 ER - TY - JOUR T1 - Assays for monitoring susceptibility of influenza viruses to neuraminidase inhibitors AN - 1272744236; 17562640 AB - Please cite this paper as: Okomo-Adhiambo et al. (2012) Assays for monitoring susceptibility of influenza viruses to neuraminidase inhibitors. Influenza and Other Respiratory Viruses 7(Suppl. 1), 44-49. Close monitoring of drug susceptibility among human influenza viruses was necessitated by widespread resistance to M2 inhibitors in influenza H1N1 (pre-pandemic and 2009 pandemic) and H3N2 viruses, and of oseltamivir resistance in pre-pandemic H1N1 viruses. The FDA-approved neuraminidase (NA) inhibitors (NAIs), oseltamivir and zanamivir, as well as investigational NAIs, peramivir and laninamivir, are currently the principal treatment options for managing influenza infection. However, there are challenges associated with assessing virus susceptibility to this class of drugs. Traditional cell culture-based assays are not reliable for phenotypic testing of NAI susceptibility due to complexity in interpretation. Two types of laboratory assays are currently available for monitoring NAI susceptibility, phenotypic such as the neuraminidase inhibition (NI) assay and genotypic. The NI assay's requirement for propagated virus lengthens testing turnaround; therefore, the need for timely detection of molecular markers associated with NAI resistance (e.g., H275Y in H1N1) has spurred the development of rapid, high-throughput assays, such as real-time RT-PCR and pyrosequencing. The high sensitivity of genotypic assays allows testing of clinical specimens thus eliminating the need for virus propagation in cell culture. The NI assays are especially valuable when a novel virus emerges or a new NAI becomes available. Modifications continue to be introduced into NI assays, including optimization and data analysis criteria. The optimal assay of choice for monitoring influenza drug susceptibility varies widely depending on the needs of laboratories (e.g., surveillance purposes, clinical settings). Optimally, it is desirable to combine functional and genetic analyses of virus isolates and, when possible, the respective clinical specimens. JF - Influenza and Other Respiratory Viruses AU - Okomo-Adhiambo, Margaret AU - Sheu, Tiffany G AU - Gubareva, Larisa V AD - Virus Surveillance and Diagnosis Branch, Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA. Y1 - 2013/01// PY - 2013 DA - Jan 2013 SP - 44 EP - 49 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 7 SN - 1750-2640, 1750-2640 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Sensitivity KW - Data processing KW - Viruses KW - Genetic analysis KW - Assays KW - Cell culture KW - Disease resistance KW - Infection KW - Zanamivir KW - Oseltamivir KW - Influenza KW - pandemics KW - Polymerase chain reaction KW - Exo- alpha -sialidase KW - Drugs KW - H 1000:Occupational Safety and Health KW - V 22310:Genetics, Taxonomy & Structure UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1272744236?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Influenza+and+Other+Respiratory+Viruses&rft.atitle=Assays+for+monitoring+susceptibility+of+influenza+viruses+to+neuraminidase+inhibitors&rft.au=Okomo-Adhiambo%2C+Margaret%3BSheu%2C+Tiffany+G%3BGubareva%2C+Larisa+V&rft.aulast=Okomo-Adhiambo&rft.aufirst=Margaret&rft.date=2013-01-01&rft.volume=7&rft.issue=&rft.spage=44&rft.isbn=&rft.btitle=&rft.title=Influenza+and+Other+Respiratory+Viruses&rft.issn=17502640&rft_id=info:doi/10.1111%2Firv.12051 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-01-01 N1 - Document feature - figure 0 N1 - Last updated - 2015-09-30 N1 - SubjectsTermNotLitGenreText - Influenza; pandemics; Data processing; Genetic analysis; Polymerase chain reaction; Cell culture; Disease resistance; Exo- alpha -sialidase; Infection; Drugs; Zanamivir; Oseltamivir; Sensitivity; Viruses; Assays DO - http://dx.doi.org/10.1111/irv.12051 ER - TY - JOUR T1 - Characteristics of non-fatal abusive head trauma among children in the USA, 2003-2008: application of the CDC operational case definition to national hospital inpatient data AN - 1551630345; 20347909 AB - ObjectiveAn International Classification of Diseases code-based case definition for non-fatal abusive head trauma (AHT) in children <5years of age was developed in March 2008 by an expert panel convened at the Centers for Disease Control and Prevention (CDC). This study presents an application of the CDC recommended operational case definition of AHT to US hospital inpatient data to characterise the AHT hospitalisation rate for children <5years of age.MethodsNationwide Inpatient Sample (NIS) data from the Healthcare Cost and Utilisation Project from 2003 to 2008 were examined.ResultsInspection of the NIS data resulted in the identification of an estimated 10[puncsp]555 non-fatal AHT hospitalisations with 9595 classified as definite/presumptive AHT and 960 classified as probable AHT. The non-fatal AHT rate was highest among children aged <1year (32.3 per 100[puncsp]000) with a peak in hospitalisations between 1 and 3months of age. Non-fatal AHT hospitalisation rates for children <2years of age were higher for boys (21.9 per 100[puncsp]000) than girls (15.3 per 100[puncsp]000). The non-fatal AHT hospitalisation rate showed little variation across seasons.ConclusionsTo reduce the burden of AHT in the USA, a preventable public health problem, concerted prevention efforts targeting populations at risk should be implemented. This report demonstrates a model procedure for using the new CDC definition for public health surveillance and research purposes. Such findings can be used to inform parents and providers about AHT (eg, dangers of shaking, strategies for managing infant crying) as well as to monitor better the impact of prevention strategies over time. JF - Injury Prevention AU - Parks, Sharyn AU - Sugerman, David AU - Xu, Likang AU - Coronado, Victor AD - National Center for Injury Prevention and Control-Division of Violence Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA Y1 - 2012/12/13/ PY - 2012 DA - 2012 Dec 13 SP - 392 EP - 398 PB - B M J Publishing Group, B.M.A. House London WC1H 9JR United Kingdom VL - 18 IS - 6 SN - 1353-8047, 1353-8047 KW - Risk Abstracts; Health & Safety Science Abstracts KW - USA KW - Prevention KW - Age KW - Classification KW - Health care KW - Injuries KW - Disease control KW - Children KW - Public health KW - Hospitals KW - Infants KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1551630345?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Injury+Prevention&rft.atitle=Characteristics+of+non-fatal+abusive+head+trauma+among+children+in+the+USA%2C+2003-2008%3A+application+of+the+CDC+operational+case+definition+to+national+hospital+inpatient+data&rft.au=Parks%2C+Sharyn%3BSugerman%2C+David%3BXu%2C+Likang%3BCoronado%2C+Victor&rft.aulast=Parks&rft.aufirst=Sharyn&rft.date=2012-12-13&rft.volume=18&rft.issue=6&rft.spage=392&rft.isbn=&rft.btitle=&rft.title=Injury+Prevention&rft.issn=13538047&rft_id=info:doi/10.1136%2Finjuryprev-2011-040234 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-08-01 N1 - Last updated - 2014-08-21 N1 - SubjectsTermNotLitGenreText - Age; Prevention; Injuries; Health care; Classification; Disease control; Children; Infants; Hospitals; Public health; USA DO - http://dx.doi.org/10.1136/injuryprev-2011-040234 ER - TY - JOUR T1 - Applying the Interactive Systems Framework to the Dissemination and Adoption of National and State Recommendations for Hypertension AN - 1494299059; 201400176 AB - The Centers for Disease Control and Prevention (CDC), Division for Heart Disease and Stroke Prevention (DHDSP), commissioned an Institute of Medicine (IOM) report to identify the highest priority action areas for CDC, state health departments, and other public health partners in their efforts to reduce and control hypertension. To assess the dissemination and adoption of the IOM report recommendations, DHDSP developed an evaluation based on the Interactive Systems Framework for Dissemination and Implementation (ISF). The evaluation incorporates data collection at critical points across 3 years. In this article, we focus on the ISF systems to describe the role of funded state partners and their relationship with CDC in implementing public health recommendations. We describe baseline results for three data collection activities: (1) key informant interviews, (2) a Web-based survey, and (3) content analysis of state workplans to determine the degree of alignment with IOM recommendations. For example, currently 30 % of surveyed programs are implementing most (or all) of the recommendations in the IOM report, however 76 % intend to change hypertension program priorities based on the recommendations of the IOM report. Qualitative data suggest that there are several facilitators and barriers in implementing public health policy recommendations. DHDSP will use these baseline results to provide additional technical assistance and support to state health departments in their efforts to implement the IOM report's recommendations. Adapted from the source document. JF - American Journal of Community Psychology AU - Lane, Rashon I AU - Berkowitz, Judy M AU - Sullivan, Steven T AU - Rose, John AU - Bernichon, Tiffiny AU - Favoretto, Alessandra AU - Shifflett, Pat AU - Miles, Eileen AU - Jones, MaryCatherine AD - National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway, M/S-K-72, Atlanta, GA, 30341, USA rlane@cdc.gov Y1 - 2012/12// PY - 2012 DA - December 2012 SP - 541 EP - 552 PB - Springer, Dordrecht The Netherlands VL - 50 IS - 3-4 SN - 0091-0562, 0091-0562 KW - Prevention KW - Methodology (Data Collection) KW - Heart Diseases KW - Public Health KW - Blood Pressure KW - Health Problems KW - State Role KW - Implementation KW - Health Care Services KW - article KW - 6111: social work theory/research UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1494299059?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocialservices&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Community+Psychology&rft.atitle=Applying+the+Interactive+Systems+Framework+to+the+Dissemination+and+Adoption+of+National+and+State+Recommendations+for+Hypertension&rft.au=Lane%2C+Rashon+I%3BBerkowitz%2C+Judy+M%3BSullivan%2C+Steven+T%3BRose%2C+John%3BBernichon%2C+Tiffiny%3BFavoretto%2C+Alessandra%3BShifflett%2C+Pat%3BMiles%2C+Eileen%3BJones%2C+MaryCatherine&rft.aulast=Lane&rft.aufirst=Rashon&rft.date=2012-12-01&rft.volume=50&rft.issue=3-4&rft.spage=541&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Community+Psychology&rft.issn=00910562&rft_id=info:doi/10.1007%2Fs10464-012-9511-0 LA - English DB - Social Services Abstracts N1 - Date revised - 2014-02-01 N1 - Last updated - 2016-09-28 N1 - CODEN - AJCPCK N1 - SubjectsTermNotLitGenreText - Blood Pressure; Public Health; Methodology (Data Collection); Prevention; Heart Diseases; Health Care Services; Health Problems; Implementation; State Role DO - http://dx.doi.org/10.1007/s10464-012-9511-0 ER - TY - JOUR T1 - Navigating the Road Ahead: Public Health Challenges and the Interactive Systems Framework for Dissemination and Implementation AN - 1434016023; 18526380 AB - Public health is currently faced with an array of critical challenges and disconnects. Research and evaluation have identified a number of evidence-based strategies for effecting behavior change at individual, group, organizational, and environmental levels, all of which hold promise for leading to substantial reductions in morbidity and mortality, and increased quality of life. Unfortunately, there is huge variability across the public health system in awareness of the value of using evidence to inform decision making, let alone in capacity to locate, assess, compare, select, justify, adapt, implement, and evaluate evidence-based strategies, or to participate in building the evidence base for practice-based innovations. As a result, many communities may not be benefitting from research-tested and practice-based strategies that could help them to meet their public health goals more efficiently and effectively. CDC's Interactive Systems Framework for Dissemination and Implementation (ISF), released in 2008, was designed to help close this gap between research and practice. This commentary identifies the ways in which the ISF framework is useful in addressing the research practice gap; revisits the elements of the framework that have continued to guide research and practice in fruitful ways; and highlights areas that need further development to meet current public health challenges. JF - American Journal of Community Psychology AU - Noonan, Rita K AU - Wilson, Katherine M AU - Mercer, Shawna L AD - National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Mailstop F-63, Atlanta, GA, 30341, USA, RNoonan@cdc.gov Y1 - 2012/12// PY - 2012 DA - Dec 2012 SP - 572 EP - 580 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 50 IS - 3-4 SN - 0091-0562, 0091-0562 KW - Health & Safety Science Abstracts KW - Mortality KW - Decision making KW - Morbidity KW - Public health KW - Innovations KW - Quality of life KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1434016023?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Community+Psychology&rft.atitle=Navigating+the+Road+Ahead%3A+Public+Health+Challenges+and+the+Interactive+Systems+Framework+for+Dissemination+and+Implementation&rft.au=Noonan%2C+Rita+K%3BWilson%2C+Katherine+M%3BMercer%2C+Shawna+L&rft.aulast=Noonan&rft.aufirst=Rita&rft.date=2012-12-01&rft.volume=50&rft.issue=3-4&rft.spage=572&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Community+Psychology&rft.issn=00910562&rft_id=info:doi/10.1007%2Fs10464-012-9534-6 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-09-01 N1 - Last updated - 2013-10-04 N1 - SubjectsTermNotLitGenreText - Decision making; Mortality; Morbidity; Quality of life; Innovations; Public health DO - http://dx.doi.org/10.1007/s10464-012-9534-6 ER - TY - JOUR T1 - Recovery of diverse microbes in high turbidity surface water samples using dead-end ultrafiltration AN - 1328510393; 17392253 AB - Dead-end ultrafiltration (DEUF) has been reported to be a simple, field-deployable technique for recovering bacteria, viruses, and parasites from large-volume water samples for water quality testing and waterborne disease investigations. While DEUF has been reported for application to water samples having relatively low turbidity, little information is available regarding recovery efficiencies for this technique when applied to sampling turbid water samples such as those commonly found in lakes and rivers. This study evaluated the effectiveness of a DEUF technique for recovering MS2 bacteriophage, enterococci, Escherichia coli, Clostridium perfringens, and Cryptosporidium parvum oocysts in surface water samples having elevated turbidity. Average recovery efficiencies for each study microbe across all turbidity ranges were: MS2 (66%), C. parvum (49%), enterococci (85%), E. coli (81%), and C. perfringens (63%). The recovery efficiencies for MS2 and C. perfringens exhibited an inversely proportional relationship with turbidity, however no significant differences in recovery were observed for C. parvum, enterococci, or E. coli. Although ultrafilter clogging was observed, the DEUF method was able to process 100-L surface water samples at each turbidity level within 60min. This study supports the use of the DEUF method for recovering a wide array of microbes in large-volume surface water samples having medium to high turbidity. JF - Journal of Microbiological Methods AU - Mull, Bonnie AU - Hill, Vincent R AD - Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases, Division of Foodborne, Waterborne and Environmental Diseases, Atlanta, GA, USA, BMull@cdc.gov Y1 - 2012/12// PY - 2012 DA - Dec 2012 SP - 429 EP - 433 PB - Elsevier B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 91 IS - 3 SN - 0167-7012, 0167-7012 KW - ASFA 1: Biological Sciences & Living Resources; Aqualine Abstracts; Water Resources Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Dead-end ultrafiltration KW - Microbial recovery KW - Turbid water KW - Ultrafiltration KW - Phages KW - Parasites KW - Water Analysis KW - Surface water KW - Water Sampling KW - Viruses KW - Surface Water KW - Water quality KW - Lakes KW - Escherichia coli KW - Diseases KW - Sampling KW - Bacteria (Enterobacteriaceae) (Escherichia) KW - Rivers KW - Bacteriophages KW - Oocysts KW - Clostridium perfringens KW - Endoparasites KW - Cryptosporidium parvum KW - Recovery KW - Turbidity KW - SW 5040:Data acquisition KW - Q1 08484:Species interactions: parasites and diseases KW - AQ 00008:Effects of Pollution KW - A 01300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1328510393?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Microbiological+Methods&rft.atitle=Recovery+of+diverse+microbes+in+high+turbidity+surface+water+samples+using+dead-end+ultrafiltration&rft.au=Mull%2C+Bonnie%3BHill%2C+Vincent+R&rft.aulast=Mull&rft.aufirst=Bonnie&rft.date=2012-12-01&rft.volume=91&rft.issue=3&rft.spage=429&rft.isbn=&rft.btitle=&rft.title=Journal+of+Microbiological+Methods&rft.issn=01677012&rft_id=info:doi/10.1016%2Fj.mimet.2012.10.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-04-01 N1 - Last updated - 2014-09-18 N1 - SubjectsTermNotLitGenreText - Bacteriophages; Parasites; Recovery; Surface water; Viruses; Water quality; Endoparasites; Turbidity; Rivers; Phages; Ultrafiltration; Lakes; Oocysts; Sampling; Bacteria (Enterobacteriaceae) (Escherichia); Water Analysis; Water Sampling; Escherichia coli; Diseases; Surface Water; Clostridium perfringens; Cryptosporidium parvum DO - http://dx.doi.org/10.1016/j.mimet.2012.10.001 ER - TY - JOUR T1 - Mercury exposure among artisanal gold miners in Madre de Dios, Peru: a cross-sectional study. AN - 1221133855; 22926732 AB - Exposure to mercury, a toxic metal, occurs primarily from inhaling mercury vapors or consuming methylmercury-contaminated fish. One third of all anthropogenic mercury emissions worldwide are from artisanal gold mining, which uses mercury to extract gold. Although recent reports suggest that the Madre de Dios region in Peru (with >30,000 artisanal miners) has extensive mercury contamination, residents had never been assessed for mercury exposure. Thus, our objective was to quantify mercury exposure among residents of an artisanal mining town in Madre de Dios and to assess risk factors for exposure. We conducted a cross-sectional assessment of 103 residents of an artisanal gold mining town in July 2010. Each participant provided a urine and blood sample and completed a questionnaire assessing potential exposures and health outcomes. We calculated geometric mean (GM) urine total mercury and blood methylmercury concentrations and compared log-transformed concentrations between subgroups using linear regression. One third (34.0 %) of participants were gold miners. All participants had detectable urine total mercury (GM, 5.5 μg/g creatinine; range, 0.7-151 μg/g creatinine) and 91 % had detectable blood methylmercury (GM, 2.7 μg/L; range, 0.6-10 μg/L); 13 participants (13 %) reported having kidney dysfunction or a neurological disorder. Urine total mercury concentrations were higher among people who heated gold-mercury amalgams compared with people who never heated amalgams (p < 0.05); methylmercury concentrations were higher among fish consumers compared with nonfish consumers (p < 0.05). Our findings suggest that mercury exposure may be widespread in Huaypetue. JF - Journal of medical toxicology : official journal of the American College of Medical Toxicology AU - Yard, Ellen E AU - Horton, Jane AU - Schier, Joshua G AU - Caldwell, Kathleen AU - Sanchez, Carlos AU - Lewis, Lauren AU - Gastaňaga, Carmen AD - Centers for Disease Control and Prevention, Epidemic Intelligence Service, Atlanta, GA 30333, USA. eyard@cdc.gov Y1 - 2012/12// PY - 2012 DA - December 2012 SP - 441 EP - 448 VL - 8 IS - 4 KW - Biomarkers KW - 0 KW - Methylmercury Compounds KW - Gold KW - 7440-57-5 KW - Creatinine KW - AYI8EX34EU KW - dimethyl mercury KW - C60TQU15XY KW - Index Medicus KW - Young Adult KW - Creatinine -- urine KW - Humans KW - Linear Models KW - Aged KW - Biomarkers -- urine KW - Child KW - Multivariate Analysis KW - Child, Preschool KW - Cross-Sectional Studies KW - Risk Factors KW - Adult KW - Peru KW - Middle Aged KW - Adolescent KW - Biomarkers -- blood KW - Male KW - Environmental Monitoring -- methods KW - Female KW - Occupational Exposure KW - Methylmercury Compounds -- urine KW - Methylmercury Compounds -- blood KW - Mining UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1221133855?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+medical+toxicology+%3A+official+journal+of+the+American+College+of+Medical+Toxicology&rft.atitle=Mercury+exposure+among+artisanal+gold+miners+in+Madre+de+Dios%2C+Peru%3A+a+cross-sectional+study.&rft.au=Yard%2C+Ellen+E%3BHorton%2C+Jane%3BSchier%2C+Joshua+G%3BCaldwell%2C+Kathleen%3BSanchez%2C+Carlos%3BLewis%2C+Lauren%3BGasta%C5%88aga%2C+Carmen&rft.aulast=Yard&rft.aufirst=Ellen&rft.date=2012-12-01&rft.volume=8&rft.issue=4&rft.spage=441&rft.isbn=&rft.btitle=&rft.title=Journal+of+medical+toxicology+%3A+official+journal+of+the+American+College+of+Medical+Toxicology&rft.issn=1937-6995&rft_id=info:doi/10.1007%2Fs13181-012-0252-0 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2013-05-02 N1 - Date created - 2012-11-30 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Bull Environ Contam Toxicol. 2011 May;86(5):484-9 [21424574] Sci Total Environ. 2010 Jan 15;408(4):796-805 [19945738] PLoS One. 2012;7(3):e33305 [22438911] Sci Total Environ. 2001 Feb 21;267(1-3):151-68 [11286210] Int Arch Occup Environ Health. 2001 Apr;74(3):206-12 [11355295] Bull Environ Contam Toxicol. 2001 Sep;67(3):317-23 [11479659] Med Lav. 2002 May-Jun;93(3):139-47 [12197264] Med Lav. 2002 May-Jun;93(3):202-14 [12197270] Sci Total Environ. 1995 May 19;168(1):63-9 [7610384] Environ Health Perspect. 1995 Sep;103 Suppl 6:135-42 [8549462] Int J Occup Environ Health. 2005 Apr-Jun;11(2):132-7 [15875888] Braz J Med Biol Res. 2006 Mar;39(3):411-4 [16501821] Int J Occup Environ Health. 2006 Oct-Dec;12(4):340-5 [17168221] Environ Res. 2008 May;107(1):89-97 [18321481] Environ Sci Technol. 2009 Oct 1;43(19):7162-4 [19848116] Sci Total Environ. 2010 Jan 15;408(4):713-25 [19945736] PLoS One. 2011;6(4):e18875 [21526143] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1007/s13181-012-0252-0 ER - TY - JOUR T1 - Genetic diversity among Clostridium botulinum strains harboring bont/A2 and bont/A3 genes. AN - 1178673735; 23042179 AB - Clostridium botulinum type A strains are known to be genetically diverse and widespread throughout the world. Genetic diversity studies have focused mainly on strains harboring one type A botulinum toxin gene, bont/A1, although all reported bont/A gene variants have been associated with botulism cases. Our study provides insight into the genetic diversity of C. botulinum type A strains, which contain bont/A2 (n = 42) and bont/A3 (n = 4) genes, isolated from diverse samples and geographic origins. Genetic diversity was assessed by using bont nucleotide sequencing, content analysis of the bont gene clusters, multilocus sequence typing (MLST), and pulsed-field gel electrophoresis (PFGE). Sequences of bont genes obtained in this study showed 99.9 to 100% identity with other bont/A2 or bont/A3 gene sequences available in public databases. The neurotoxin gene clusters of the subtype A2 and A3 strains analyzed in this study were similar in gene content. C. botulinum strains harboring bont/A2 and bont/A3 genes were divided into six and two MLST profiles, respectively. Four groups of strains shared a similarity of at least 95% by PFGE; the largest group included 21 out of 46 strains. The strains analyzed in this study showed relatively limited genetic diversity using either MLST or PFGE. JF - Applied and environmental microbiology AU - Lúquez, Carolina AU - Raphael, Brian H AU - Joseph, Lavin A AU - Meno, Sarah R AU - Fernández, Rafael A AU - Maslanka, Susan E AD - Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. CLuquez@cdc.gov Y1 - 2012/12// PY - 2012 DA - December 2012 SP - 8712 EP - 8718 VL - 78 IS - 24 KW - DNA, Bacterial KW - 0 KW - Botulinum Toxins, Type A KW - EC 3.4.24.69 KW - Index Medicus KW - Animals KW - Humans KW - Multigene Family KW - DNA Fingerprinting KW - Sequence Homology KW - Sequence Analysis, DNA KW - Botulism -- veterinary KW - Multilocus Sequence Typing KW - Genotype KW - Botulism -- microbiology KW - DNA, Bacterial -- chemistry KW - DNA, Bacterial -- genetics KW - Electrophoresis, Gel, Pulsed-Field KW - Molecular Sequence Data KW - Environmental Microbiology KW - Genetic Variation KW - Clostridium botulinum -- classification KW - Botulinum Toxins, Type A -- genetics KW - Clostridium botulinum -- isolation & purification KW - Clostridium botulinum -- genetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1178673735?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+environmental+microbiology&rft.atitle=Genetic+diversity+among+Clostridium+botulinum+strains+harboring+bont%2FA2+and+bont%2FA3+genes.&rft.au=L%C3%BAquez%2C+Carolina%3BRaphael%2C+Brian+H%3BJoseph%2C+Lavin+A%3BMeno%2C+Sarah+R%3BFern%C3%A1ndez%2C+Rafael+A%3BMaslanka%2C+Susan+E&rft.aulast=L%C3%BAquez&rft.aufirst=Carolina&rft.date=2012-12-01&rft.volume=78&rft.issue=24&rft.spage=8712&rft.isbn=&rft.btitle=&rft.title=Applied+and+environmental+microbiology&rft.issn=1098-5336&rft_id=info:doi/10.1128%2FAEM.02428-12 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2013-04-22 N1 - Date created - 2012-11-19 N1 - Date revised - 2017-01-13 N1 - Genetic sequence - JX110946; GENBANK; JX110947; JX110948; JX110949; JX110967; JX110968; JX110969; JX110963; JX110964; JX110965; JX110966; JX110960; JX110961; JX110962; JX110973; JX110972; JX110971; JX110970; JX110958; JX110959; JX110975; JX110956; JX110974; JX110957; JX110954; JX110955; JX110952; JX110953; JX110950; JX110951 N1 - SuppNotes - Cited By: Infect Immun. 2005 Sep;73(9):5450-7 [16113261] J Clin Microbiol. 2005 Jun;43(6):2602-7 [15956371] FEBS Lett. 2012 Jan 20;586(2):109-15 [22172278] FEMS Microbiol Lett. 2006 Aug;261(1):88-94 [16842364] J Bacteriol. 2007 Feb;189(3):818-32 [17114256] Mol Biol Evol. 2007 Aug;24(8):1596-9 [17488738] J Bacteriol. 2007 Dec;189(23):8643-50 [17905976] Appl Environ Microbiol. 2008 Feb;74(3):875-82 [18083878] Appl Environ Microbiol. 2008 May;74(9):2778-86 [18326685] Pediatrics. 2008 Jul;122(1):e73-82 [18595978] Appl Environ Microbiol. 2008 Jul;74(14):4390-7 [18502928] BMC Genomics. 2009;10:115 [19298644] J Clin Microbiol. 2009 Jul;47(7):2349-50 [19420169] Appl Environ Microbiol. 2009 Oct;75(19):6094-101 [19684172] BMC Biol. 2009;7:66 [19804621] Appl Environ Microbiol. 2010 Jul;76(14):4805-12 [20511432] J Appl Microbiol. 1998 Jan;84(1):5-17 [15244052] BMC Bioinformatics. 2004 Jul 1;5:86 [15230973] Appl Environ Microbiol. 1995 Dec;61(12):4441-7 [8534108] Appl Environ Microbiol. 1998 Feb;64(2):703-8 [9464411] Appl Environ Microbiol. 2004 Dec;70(12):7192-9 [15574917] Appl Environ Microbiol. 2005 Mar;71(3):1148-54 [15746312] Appl Environ Microbiol. 2005 Mar;71(3):1311-7 [15746333] Appl Environ Microbiol. 2011 Dec;77(24):8625-34 [22003031] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1128/AEM.02428-12 ER - TY - JOUR T1 - Obesity, Assisted Reproductive Technology, and Early Preterm Birth-Florida, 2004-2006 AN - 1291607828; 17591395 AB - Florida resident birth certificates for 2004-2006 were linked to the Centers for Disease Control and Prevention's National ART Surveillance System and were used to investigate 1) whether the association of assisted reproductive technology (ART) with preterm birth varies by prepregnancy body mass index and 2) whether the association varies by plurality. Preterm birth was defined as early preterm birth (gestation <34 weeks) and late preterm birth (gestation 34-36 weeks). Descriptive statistics and multinomial logistic regression were used to explore maternal and infant differences by ART status and plurality. Of 581,403 women included in the study, 24.0% were overweight, 18.6% were obese, 7.3% had late preterm birth, 2.6% had early preterm birth, and 0.67% conceived through ART. Among singleton births, ART was associated with increased early preterm birth risk among underweight (odds ratio (OR) = 2.94, 95% confidence interval (CI): 1.27, 6.81), overweight (OR = 1.75, 95% CI: 1.12, 2.72), and obese (OR = 2.37, 95% CI: 1.51, 3.71) women. Among twins, ART was significantly associated with increased risk among overweight (OR = 1.61, 95% CI: 1.12, 2.32) and obese (OR = 1.85, 95% CI: 1.18, 2.90) women. Differences in the associations between ART and early preterm birth by body mass index and plurality warrant further investigation. JF - American Journal of Epidemiology AU - Sauber-Schatz, Erin K AU - Sappenfield, William AU - Grigorescu, Violanda AU - Kulkarni, Aniket AU - Zhang, Yujia AU - Salihu, Hamisu M AU - Rubin, Lewis P AU - Kirby, Russell S AU - Jamieson, Denise J AU - Macaluso, Maurizio Y1 - 2012/11/15/ PY - 2012 DA - 2012 Nov 15 SP - 886 EP - 896 PB - Oxford University Press, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 176 IS - 10 SN - 0002-9262, 0002-9262 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Obesity KW - Prevention KW - USA, Florida KW - Body mass KW - Disease control KW - Reproductive technology KW - Pregnancy KW - Infants KW - R2 23060:Medical and environmental health KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1291607828?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Epidemiology&rft.atitle=Obesity%2C+Assisted+Reproductive+Technology%2C+and+Early+Preterm+Birth-Florida%2C+2004-2006&rft.au=Sauber-Schatz%2C+Erin+K%3BSappenfield%2C+William%3BGrigorescu%2C+Violanda%3BKulkarni%2C+Aniket%3BZhang%2C+Yujia%3BSalihu%2C+Hamisu+M%3BRubin%2C+Lewis+P%3BKirby%2C+Russell+S%3BJamieson%2C+Denise+J%3BMacaluso%2C+Maurizio&rft.aulast=Sauber-Schatz&rft.aufirst=Erin&rft.date=2012-11-15&rft.volume=176&rft.issue=10&rft.spage=886&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Epidemiology&rft.issn=00029262&rft_id=info:doi/10.1093%2Faje%2Fkws155 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-01 N1 - Last updated - 2013-11-04 N1 - SubjectsTermNotLitGenreText - Obesity; Prevention; Body mass; Disease control; Reproductive technology; Infants; Pregnancy; USA, Florida DO - http://dx.doi.org/10.1093/aje/kws155 ER - TY - JOUR T1 - Neurodegenerative causes of death among retired National Football League players AN - 1291611445; 17686170 AB - Objective: To analyze neurodegenerative causes of death, specifically Alzheimer disease (AD), Parkinson disease, and amyotrophic lateral sclerosis (ALS), among a cohort of professional football players. Methods: This was a cohort mortality study of 3,439 National Football League players with at least 5 pension-credited playing seasons from 1959 to 1988. Vital status was ascertained through 2007. For analysis purposes, players were placed into 2 strata based on characteristics of position played; nonspeed players (linemen) and speed players (all other positions except punter/kicker). External comparisons with the US population used standardized mortality ratios (SMRs); internal comparisons between speed and nonspeed player positions used standardized rate ratios (SRRs). Results: Overall player mortality compared with that of the US population was reduced (SMR 0.53, 95% confidence interval [CI] 0.48-0.59). Neurodegenerative mortality was increased using both underlying cause of death rate files (SMR 2.83, 95% CI 1.36-5.21) and multiple cause of death (MCOD) rate files (SMR 3.26, 95% CI 1.90-5.22). Of the neurodegenerative causes, results were elevated (using MCOD rates) for both ALS (SMR 4.31, 95% CI 1.73-8.87) and AD (SMR 3.86, 95% CI 1.55-7.95). In internal analysis (using MCOD rates), higher neurodegenerative mortality was observed among players in speed positions compared with players in nonspeed positions (SRR 3.29, 95% CI 0.92-11.7). Conclusions: The neurodegenerative mortality of this cohort is 3 times higher than that of the general US population; that for 2 of the major neurodegenerative subcategories, AD and ALS, is 4 times higher. These results are consistent with recent studies that suggest an increased risk of neurodegenerative disease among football players. JF - Neurology AU - Lehman, E J AU - Hein, MJ AU - Baron, S L AU - Gersic, C M Y1 - 2012/11/06/ PY - 2012 DA - 2012 Nov 06 SP - 1970 EP - 1974 VL - 79 IS - 19 SN - 0028-3878, 0028-3878 KW - Physical Education Index; CSA Neurosciences Abstracts KW - Football (American KW - Mortality KW - Death KW - Parkinson's disease KW - Alzheimer's disease KW - Professional sports KW - Neurodegenerative diseases KW - Speed KW - Amyotrophic lateral sclerosis KW - Movement disorders KW - Analysis KW - Objectives KW - Associations KW - Diseases KW - Athletes KW - players) KW - PE 040:Sports & Athletics KW - N3 11027:Neurology & neuropathology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1291611445?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurology&rft.atitle=Neurodegenerative+causes+of+death+among+retired+National+Football+League+players&rft.au=Lehman%2C+E+J%3BHein%2C+MJ%3BBaron%2C+S+L%3BGersic%2C+C+M&rft.aulast=Lehman&rft.aufirst=E&rft.date=2012-11-06&rft.volume=79&rft.issue=19&rft.spage=1970&rft.isbn=&rft.btitle=&rft.title=Neurology&rft.issn=00283878&rft_id=info:doi/10.1212%2FWNL.0b013e31826daf50 LA - English DB - Physical Education Index N1 - Date revised - 2013-02-01 N1 - Last updated - 2013-08-12 N1 - SubjectsTermNotLitGenreText - Football (American; Speed; Death; Objectives; Analysis; Associations; Diseases; Professional sports; players); Athletes; Mortality; Neurodegenerative diseases; Movement disorders; Amyotrophic lateral sclerosis; Parkinson's disease; Alzheimer's disease DO - http://dx.doi.org/10.1212/WNL.0b013e31826daf50 ER - TY - JOUR T1 - Direct healthcare costs of selected diseases primarily or partially transmitted by water AN - 1560128770; 18059254 AB - Despite US sanitation advancements, millions of waterborne disease cases occur annually, although the precise burden of disease is not well quantified. Estimating the direct healthcare cost of specific infections would be useful in prioritizing waterborne disease prevention activities. Hospitalization and outpatient visit costs per case and total US hospitalization costs for ten waterborne diseases were calculated using large healthcare claims and hospital discharge databases. The five primarily waterborne diseases in this analysis (giardiasis, cryptosporidiosis, Legionnaires' disease, otitis externa, and non-tuberculous mycobacterial infection) were responsible for over 40 000 hospitalizations at a cost of $970 million per year, including at least $430 million in hospitalization costs for Medicaid and Medicare patients. An additional 50 000 hospitalizations for campylobacteriosis, salmonellosis, shigellosis, haemolytic uraemic syndrome, and toxoplasmosis cost $860 million annually ($390 million in payments for Medicaid and Medicare patients), a portion of which can be assumed to be due to waterborne transmission. JF - Epidemiology and Infection AU - Collier, Sa AU - Stockman, L J AU - Hicks, La AU - Garrison, Le AU - Zhou, F J AU - Beach, MJ AD - International Health Resources Consulting, Inc., Atlanta, GA, USA, scollier@cdc.gov Y1 - 2012/11// PY - 2012 DA - Nov 2012 SP - 2003 EP - 2013 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 140 IS - 11 SN - 0950-2688, 0950-2688 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources KW - Costs KW - Symptoms KW - Epidemiology KW - Mycobacterium KW - Anadromous species KW - Tuberculosis KW - Salmonidae KW - Disease transmission KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1560128770?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Direct+healthcare+costs+of+selected+diseases+primarily+or+partially+transmitted+by+water&rft.au=Collier%2C+Sa%3BStockman%2C+L+J%3BHicks%2C+La%3BGarrison%2C+Le%3BZhou%2C+F+J%3BBeach%2C+MJ&rft.aulast=Collier&rft.aufirst=Sa&rft.date=2012-11-01&rft.volume=140&rft.issue=11&rft.spage=2003&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268811002858 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-09-01 N1 - Number of references - 38 N1 - Last updated - 2014-12-11 N1 - SubjectsTermNotLitGenreText - Costs; Symptoms; Epidemiology; Anadromous species; Tuberculosis; Disease transmission; Mycobacterium; Salmonidae DO - http://dx.doi.org/10.1017/S0950268811002858 ER - TY - JOUR T1 - Eight years of Legionnaires' disease transmission in travellers to a condominium complex in Las Vegas, Nevada AN - 1367488140; 18059256 AB - Travel is a risk factor for Legionnaires' disease. In 2008, two cases were reported in condominium guests where we investigated a 2001 outbreak. We reinvestigated to identify additional cases and determine whether ongoing transmission resulted from persistent colonization of potable water. Exposures were assessed by matched case-control analyses (2001) and case-series interviews (2008). We sampled potable water and other water sources. Isolates were compared using sequence-based typing. From 2001 to 2008, 35 cases were identified. Confirmed cases reported after the cluster in 2001-2002 were initially considered sporadic, but retrospective case-finding identified five additional cases. Cases were more likely than controls to stay in tower 2 of the condominium [matched odds ratio (mOR) 6.1, 95% confidence interval (CI) 1.6-22.9]; transmission was associated with showering duration (mOR 23.0, 95% CI 1.4-384). We characterized a clinical isolate as sequence type 35 (ST35) and detected ST35 in samples of tower 2's potable water in 2001, 2002, and 2008. This prolonged outbreak illustrates the importance of striving for permanent Legionella eradication from potable water. JF - Epidemiology and Infection AU - Silk, B J AU - Moore, M R AU - BERGTHOLDT, M AU - GORWITZ, R J AU - Kozak, Na AU - Tha, M M AU - Brown, E W AU - Winchester, J L AU - Labus, B J AU - Rowley, P AU - Middaugh, J P AU - Fields, B S AU - Hicks, La AD - Respiratory Diseases Branch, Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA, bsilk@cdc.gov Y1 - 2012/11// PY - 2012 DA - Nov 2012 SP - 1993 EP - 2002 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 140 IS - 11 SN - 0950-2688, 0950-2688 KW - Microbiology Abstracts B: Bacteriology; Risk Abstracts KW - Clinical isolates KW - Travel KW - Travellers KW - USA, Nevada, Las Vegas KW - USA, Nevada KW - Legionnaire's disease KW - Disease transmission KW - Colonization KW - Typing KW - Risk factors KW - Outbreaks KW - Drinking water KW - Legionella KW - R2 23060:Medical and environmental health KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1367488140?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Eight+years+of+Legionnaires%27+disease+transmission+in+travellers+to+a+condominium+complex+in+Las+Vegas%2C+Nevada&rft.au=Silk%2C+B+J%3BMoore%2C+M+R%3BBERGTHOLDT%2C+M%3BGORWITZ%2C+R+J%3BKozak%2C+Na%3BTha%2C+M+M%3BBrown%2C+E+W%3BWinchester%2C+J+L%3BLabus%2C+B+J%3BRowley%2C+P%3BMiddaugh%2C+J+P%3BFields%2C+B+S%3BHicks%2C+La&rft.aulast=Silk&rft.aufirst=B&rft.date=2012-11-01&rft.volume=140&rft.issue=11&rft.spage=1993&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268811002779 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-06-01 N1 - Number of references - 25 N1 - Last updated - 2013-07-26 N1 - SubjectsTermNotLitGenreText - Travel; Clinical isolates; Colonization; Typing; Risk factors; Travellers; Drinking water; Disease transmission; Outbreaks; Legionnaire's disease; Legionella; USA, Nevada, Las Vegas; USA, Nevada DO - http://dx.doi.org/10.1017/S0950268811002779 ER - TY - JOUR T1 - Multistate outbreak of Salmonella serotype Typhimurium infections associated with consumption of restaurant tomatoes, USA, 2006: hypothesis generation through case exposures in multiple restaurant clusters AN - 1367487535; 18059248 AB - Multiple salmonellosis outbreaks have been linked to contaminated tomatoes. We investigated a multistate outbreak of Salmonella Typhimurium infections among 190 cases. For hypothesis generation, review of patients' food histories from four restaurant-associated clusters in four states revealed that large tomatoes were the only common food consumed by patients. Two case-control studies were conducted to identify food exposures associated with infections. In a study conducted in nine states illness was significantly associated with eating raw, large, round tomatoes in a restaurant [matched odds ratio (mOR) 3.1, 95% confidence interval (CI) 1.3-7.3]. In a Minnesota study, illness was associated with tomatoes eaten at a restaurant (OR 6.3, mid-P 95% CI 1.05-50.4, P=0.046). State, local and federal regulatory officials traced the source of tomatoes to Ohio tomato fields, a growing area not previously identified in past tomato-associated outbreaks. Because tomatoes are commonly eaten raw, prevention of tomato contamination should include interventions on the farm, during packing, and at restaurants. JF - Epidemiology and Infection AU - BEHRAVESH, CBARTON AU - Blaney, D AU - MEDUS, C AU - BIDOL, SA AU - Phan, Q AU - SOLIVA, S AU - Daly, E R AU - Smith, K AU - Miller, B AU - Taylor, T AU - Nguyen, T AU - Perry, C AU - Hill, T A AU - Fogg, N AU - KLEIZA, A AU - Moorhead, D AU - Al-Khaldi, S AU - Braden, C AU - Lynch, M F AD - Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA, CBartonBehravesh@cdc.gov Y1 - 2012/11// PY - 2012 DA - Nov 2012 SP - 2053 EP - 2061 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 140 IS - 11 SN - 0950-2688, 0950-2688 KW - Pollution Abstracts; Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts KW - Farms KW - Lycopersicon esculentum KW - Outbreaks KW - Infection KW - USA, Minnesota KW - H 12000:Epidemiology and Public Health KW - J 02400:Human Diseases KW - P 6000:TOXICOLOGY AND HEALTH UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1367487535?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Multistate+outbreak+of+Salmonella+serotype+Typhimurium+infections+associated+with+consumption+of+restaurant+tomatoes%2C+USA%2C+2006%3A+hypothesis+generation+through+case+exposures+in+multiple+restaurant+clusters&rft.au=BEHRAVESH%2C+CBARTON%3BBlaney%2C+D%3BMEDUS%2C+C%3BBIDOL%2C+SA%3BPhan%2C+Q%3BSOLIVA%2C+S%3BDaly%2C+E+R%3BSmith%2C+K%3BMiller%2C+B%3BTaylor%2C+T%3BNguyen%2C+T%3BPerry%2C+C%3BHill%2C+T+A%3BFogg%2C+N%3BKLEIZA%2C+A%3BMoorhead%2C+D%3BAl-Khaldi%2C+S%3BBraden%2C+C%3BLynch%2C+M+F&rft.aulast=BEHRAVESH&rft.aufirst=CBARTON&rft.date=2012-11-01&rft.volume=140&rft.issue=11&rft.spage=2053&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268811002895 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-06-01 N1 - Number of references - 1 N1 - Last updated - 2014-03-10 N1 - SubjectsTermNotLitGenreText - Infection; Outbreaks; Lycopersicon esculentum; USA, Minnesota DO - http://dx.doi.org/10.1017/S0950268811002895 ER - TY - JOUR T1 - Pulmonary exposure of rats to ultrafine titanium dioxide enhances cardiac protein phosphorylation and substance P synthesis in nodose ganglia AN - 1328522164; 17904310 AB - The inhalation of engineered nanoparticles stimulates the development of atherosclerosis and impairs vascular function. However, the cardiac effects of inhaled engineered nanoparticles are unknown. Here, we investigate the effects of ultrafine titanium dioxide (UFTiO sub(2)) on the heart, and we define the possible mechanisms underlying the measured effects. Pulmonary exposure of rats to UFTiO sub(2) increased the phosphorylation levels of p38 mitogen-activated protein kinase and cardiac troponin I, but not Akt, in the heart and substance P synthesis in nodose ganglia. Circulatory levels of pro-inflammatory cytokines, and blood cell counts and differentials were not significantly changed after pulmonary exposure. Separately, the incubation of cardiac myocytes isolated from naive adult rat hearts in vitro with UFTiO sub(2) did not alter the phosphorylation status of the same cardiac proteins. In conclusion, the inhalation of UFTiO sub(2) enhanced the phosphorylation levels of cardiac proteins. Such responses are likely independent of systemic inflammation, but may involve a lung-neuron-regulated pathway. JF - Nanotoxicology AU - Kan, H AU - Wu, Z AU - Young, S-H AU - Chen, T-H AU - Cumpston, J L AU - Chen, F AU - Kashon, M L AU - Castranova, V AD - PPRB/NIOSH, 1095 Willowdale Road, Morgantown, WV 26505, USA, hvn4@cdc.gov Y1 - 2012/11// PY - 2012 DA - Nov 2012 SP - 736 EP - 745 VL - 6 IS - 7 SN - 1743-5390, 1743-5390 KW - CSA Neurosciences Abstracts; Toxicology Abstracts KW - AKT protein KW - Heart KW - N3:11003 KW - X:24490 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1328522164?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Nanotoxicology&rft.atitle=Pulmonary+exposure+of+rats+to+ultrafine+titanium+dioxide+enhances+cardiac+protein+phosphorylation+and+substance+P+synthesis+in+nodose+ganglia&rft.au=Kan%2C+H%3BWu%2C+Z%3BYoung%2C+S-H%3BChen%2C+T-H%3BCumpston%2C+J+L%3BChen%2C+F%3BKashon%2C+M+L%3BCastranova%2C+V&rft.aulast=Kan&rft.aufirst=H&rft.date=2012-11-01&rft.volume=6&rft.issue=7&rft.spage=736&rft.isbn=&rft.btitle=&rft.title=Nanotoxicology&rft.issn=17435390&rft_id=info:doi/10.3109%2F17435390.2011.611915 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-04-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Heart DO - http://dx.doi.org/10.3109/17435390.2011.611915 ER - TY - JOUR T1 - Mosquitoes of Western Uganda AN - 1328514831; 17396412 AB - The mosquito fauna in many areas of western Uganda has never been studied and is currently unknown. One area, Bwamba County, has been previously studied and documented but the species lists have not been updated for >40 yr. This paucity of data makes it difficult to determine which arthropod-borne viruses pose a risk to human or animal populations. Using CO2 baited-light traps, from 2008 through 2010, 67,731 mosquitoes were captured at five locations in western Uganda including Mweya, Sempaya, Maramagambo, Bwindi (BINP), and Kibale (KNP). Overall, 88 mosquito species, 7 subspecies, and 7 species groups in 10 genera were collected. The largest number of species was collected at Sempaya (65 species), followed by Maramagambo (45), Mweya (34), BINP (33), and KNP (22). However, species diversity was highest in BINP (Simpson's Diversity Index 1-D = 0.85), followed by KNP (0.80), Maramagambo (0.79), Sempaya (0.67), and Mweya (0.56). Only six species Aedes (Aedimorphus) cumminsii (Theobald), Aedes (Neomelaniconion) circumluteolus (Theobald), Culex (Culex) antennatus (Becker), Culex (Culex) decens group, Culex (Lutzia) tigripes De Grandpre and De Charmoy, and Culex (Oculeomyia) annulions (Theobald), were collected from all five sites suggesting large differences in species composition among sites. Four species (Aedes (Stegomyia) metallicus (Edwards), Anopheles (Cellia) rivulorum Leeson, Uranotaenia (Uranotaenia) chorleyi (Edwards), and Uranotaenia (Uranotaenia) pallidocephala (Theobald) and one subspecies (Aedes (Stegomyia) aegypti formosus (Walker)) were collected in Bwamba County for the first time. This study represents the first description of the mosquito species composition of Mweya, Maramagambo, BINP, and KNP. A number of morphological variations were noted regarding the postspiracular scales, hind tibia, and sternites that make Culex (Culex) neavei (Theobald) challenging to identify. At least 50 species collected in this study have previously been implicated in the transmission of arboviruses of public health importance suggesting a high potential for maintenance and transmission of a wide variety of arboviruses in western Uganda. JF - Journal of Medical Entomology AU - Mutebi, J-P AU - Crabtree, M B AU - Kading, R C AU - Powers, A M AU - Lutwama, J J AU - Miller, B R AD - Centers for Disease Control and Prevention (CDC), 3150 Rampart Road, Fort Collins, CO 80521., jmutebi@cdc.gov Y1 - 2012/11// PY - 2012 DA - Nov 2012 SP - 1289 EP - 1306 PB - Entomological Society of America, 9301 Annapolis Rd. Lanham MD 20706 United States VL - 49 IS - 6 SN - 0022-2585, 0022-2585 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Entomology Abstracts KW - mosquito KW - species composition KW - Uganda KW - Mweya KW - Sempaya KW - Aedes KW - Data processing KW - Chromium KW - Anopheles KW - Animal populations KW - Viruses KW - Check lists KW - Uranotaenia KW - Species Composition KW - Public health KW - Tibia KW - Culex KW - Animal morphology KW - Species diversity KW - Traps KW - Species composition KW - Carbon dioxide KW - Aquatic insects KW - Q1 08484:Species interactions: parasites and diseases KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1328514831?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Medical+Entomology&rft.atitle=Mosquitoes+of+Western+Uganda&rft.au=Mutebi%2C+J-P%3BCrabtree%2C+M+B%3BKading%2C+R+C%3BPowers%2C+A+M%3BLutwama%2C+J+J%3BMiller%2C+B+R&rft.aulast=Mutebi&rft.aufirst=J-P&rft.date=2012-11-01&rft.volume=49&rft.issue=6&rft.spage=1289&rft.isbn=&rft.btitle=&rft.title=Journal+of+Medical+Entomology&rft.issn=00222585&rft_id=info:doi/10.1603%2FME10243 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-04-01 N1 - Number of references - 57 N1 - Last updated - 2014-11-12 N1 - SubjectsTermNotLitGenreText - Animal morphology; Animal populations; Species diversity; Viruses; Check lists; Carbon dioxide; Aquatic insects; Species Composition; Public health; Tibia; Data processing; Chromium; Traps; Species composition; Culex; Aedes; Anopheles; Uranotaenia; Uganda DO - http://dx.doi.org/10.1603/ME10243 ER - TY - JOUR T1 - Maternity Care Practices and Breastfeeding Experiences of Women in Different Racial and Ethnic Groups: Pregnancy Risk Assessment and Monitoring System (PRAMS) AN - 1272709718; 17447961 AB - Research shows that maternity care practices are important to promoting breastfeeding in the early post partum period; however, little is known about the association between maternity care practices and breastfeeding among different racial and ethnic groups. We examined the association between maternity care practices and breastfeeding duration to greater than or equal to 10 weeks overall and among various racial and ethnic groups using data from the Pregnancy Risk Assessment and Monitoring System (PRAMS). PRAMS is a state, population-based surveillance system that collects information on maternal behaviors. We used maternity care practices data from 11 states and New York City with response rates greater than or equal to 70% from 2004 to 2006. Multiple maternity care practices were examined and the analysis adjusted for demographic characteristics, participation in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC), lifestyle, and infant variables. The outcome variable for multivariable analysis was breastfeeding duration to <10 weeks or greater than or equal to 10 weeks. PRAMS data show that 22.1% of women did not breastfeed, about 27.7% breastfed for <10 weeks and 50.2% breastfed for greater than or equal to 10 weeks. Breastfeeding patterns varied with white and Hispanic women reporting highest breastfeeding initiation and duration prevalence. Overall, practices positively associated with greater than or equal to 10 duration were: breastfeeding initiated within the first hour after birth (adjusted OR [AOR] = 1.29; 95% CI: 1.16-1.45); fed breast milk only (AOR = 2.40; 95% CI: 2.15-2.68); breastfed on demand (AOR = 1.23; 95% CI 1.08-1.40) and receiving telephone support (AOR = 1.20; 95% CI: 1.03-1.39). Maternity care practices associated with breastfeeding to greater than or equal to 10 weeks varied across three racial/ethnic groups. One practice, that of giving newborns breast milk only, was positively associated with breastfeeding duration of greater than or equal to 10 weeks across all three groups. Maternity care practices associated with breastfeeding continuation to greater than or equal to 10 weeks varied by race/ethnicity. For example: breastfeeding within the first hour, baby given a pacifier, and assistance from hospital staff, were significantly associated with breastfeeding duration among black and white women and not Hispanics. The practice of breastfeeding on demand was significantly associated with breastfeeding to greater than or equal to 10 weeks for black and Hispanic women and not for whites. Hospitals may want to examine the implementation of specific practices in relation to the cultural backgrounds of women to promote breastfeeding. JF - Maternal and Child Health Journal AU - Ahluwalia, Indu B AU - Morrow, Brian AU - D'Angelo, Denise AU - Li, Ruowei AD - Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, Mail-stop K-22, Atlanta, GA, 30341-3724, USA, Iahluwalia@cdc.gov Y1 - 2012/11// PY - 2012 DA - Nov 2012 SP - 1672 EP - 1678 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 16 IS - 8 SN - 1092-7875, 1092-7875 KW - Risk Abstracts KW - Breast feeding KW - Breast milk KW - Culture KW - Ethnic groups KW - Hospitals KW - Infants KW - Medical personnel KW - Pregnancy KW - Risk assessment KW - USA, New York, New York City KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1272709718?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Maternal+and+Child+Health+Journal&rft.atitle=Maternity+Care+Practices+and+Breastfeeding+Experiences+of+Women+in+Different+Racial+and+Ethnic+Groups%3A+Pregnancy+Risk+Assessment+and+Monitoring+System+%28PRAMS%29&rft.au=Ahluwalia%2C+Indu+B%3BMorrow%2C+Brian%3BD%27Angelo%2C+Denise%3BLi%2C+Ruowei&rft.aulast=Ahluwalia&rft.aufirst=Indu&rft.date=2012-11-01&rft.volume=16&rft.issue=8&rft.spage=1672&rft.isbn=&rft.btitle=&rft.title=Maternal+and+Child+Health+Journal&rft.issn=10927875&rft_id=info:doi/10.1007%2Fs10995-011-0871-0 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-01-01 N1 - Last updated - 2013-01-25 N1 - SubjectsTermNotLitGenreText - Risk assessment; Culture; Breast milk; Breast feeding; Medical personnel; Ethnic groups; Hospitals; Pregnancy; Infants; USA, New York, New York City DO - http://dx.doi.org/10.1007/s10995-011-0871-0 ER - TY - JOUR T1 - Empathy and avoidance in treating patients living with HIV/AIDS (PLWHA) among service providers in China AN - 1230593692; 4371691 AB - This study aims to investigate health care providers' empathy levels and its association with avoidance in providing service to patients living with HIV/AIDS (PLWHA) in China. A total of 1760 health service providers were randomly sampled from 40 county hospitals in two provinces of China. Using a self-administered questionnaire, participants' demographic characteristics, work history, empathy level, and avoidance attitudes toward PLWHA were collected in a cross-sectional survey. Empathy was higher among participants aged 31-40 years, those who had an associated medical degree, and those who had served in the medical profession for less than 20 years. Nurses, younger providers, and providers with lower education tended to avoid contact with PLWHA. Multiple linear regression model showed that a higher level of empathic attitude toward patients was significantly negatively associated with avoidance attitude toward PLWHA. Service providers' empathy level plays an important role in providing quality care to HIV-infected patients. Future stigma reduction interventions should cultivate empathy as a platform for understanding, effective communication, and trusting provider-patient relationships. PLWHA could potentially benefit from attitudinal change in medical settings. Reprinted by permission of Routledge, Taylor & Francis Ltd. JF - AIDS care AU - Lin, Chunqing AU - Li, Li AU - Wan, Dai AU - Wu, Zunyou AU - Yan, Zhihua AD - University of California, Los Angeles ; Chinese Center for Disease Control and Prevention Y1 - 2012/11// PY - 2012 DA - Nov 2012 SP - 1341 EP - 1348 VL - 24 IS - 11 SN - 0954-0121, 0954-0121 KW - Sociology KW - Attitudes KW - Avoidance KW - AIDS KW - Cross-sectional analysis KW - Patients KW - HIV KW - Health services KW - Stigma KW - China KW - Medical personnel KW - Empathy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1230593692?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+care&rft.atitle=Empathy+and+avoidance+in+treating+patients+living+with+HIV%2FAIDS+%28PLWHA%29+among+service+providers+in+China&rft.au=Lin%2C+Chunqing%3BLi%2C+Li%3BWan%2C+Dai%3BWu%2C+Zunyou%3BYan%2C+Zhihua&rft.aulast=Lin&rft.aufirst=Chunqing&rft.date=2012-11-01&rft.volume=24&rft.issue=11&rft.spage=1341&rft.isbn=&rft.btitle=&rft.title=AIDS+care&rft.issn=09540121&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 4197 4196; 12258 11762 11859 11856; 9271 7890 5792 10484; 5703 3617 6220; 482 3617 6220; 5792 10484; 1378 10404; 3063 971; 7884 13682; 1427; 93 116 30 ER - TY - JOUR T1 - Demographic and behavioral determinants of self-reported history of sexually-transmitted diseases (STDs) among young migrant men who have sex with men (MSM) in Beijing, China AN - 1230590084; 4371383 AB - Background: Sexually-transmitted disease (STD) is a facilitating cofactor that contributes to human immunodeficiency virus (HIV) transmission. Previous studies indicated a high prevalence of STDs among men who have sex with men (MSM) in China. To date, limited data are available for correlates of STD infection among young migrant MSM in China. The current study intends to examine the association between demographic and behavioral factors and STD infection. Methods: Data were collected from a sample of 307 migrant MSM aged 1829 years in Beijing in 2009. Multivariate logistic regression analysis was employed to examine the factors associated with a history of STDs. Results: Results showed that about 13% of MSM reported a history of STDs. The average number of lifetime sexual partners was 15.0. About 56.7% of MSM did not use a condom at the first sexual encounter. The percentage of MSM who used a condom consistently was 47.4%. Multivariate logistic regression results showed that STD history was positively associated with education, income, the number of lifetime male sexual partners, and negatively associated with the frequency of properly using a condom. Conclusion: STD history was associated with socioeconomic status and sexual risk behaviors. The results suggested that HIV prevention intervention programs need to educate MSM to reduce the number of sexual partners and to use a condom properly. Furthermore, HIV prevention intervention programs among MSM need to be tailored to meet the needs of different socioeconomic groups of MSM. Reprinted by permission of Sage Publications Ltd JF - Health education journal AU - Song, Yan AU - Li, Xiaoming AU - Zhang, Liying AU - Liu, Yingjie AU - Jiang, Shulin AU - Stanton, Bonita AD - Fudan University ; Wayne State University ; Chaoyang District Center for Disease Control and Prevention Y1 - 2012/11// PY - 2012 DA - Nov 2012 SP - 699 EP - 708 VL - 71 IS - 6 SN - 0017-8969, 0017-8969 KW - Sociology KW - Prevention KW - Men KW - AIDS KW - Regression analysis KW - Homosexuality KW - HIV KW - China KW - Sexually transmitted diseases KW - Migrants KW - Homosexuals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1230590084?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+education+journal&rft.atitle=Demographic+and+behavioral+determinants+of+self-reported+history+of+sexually-transmitted+diseases+%28STDs%29+among+young+migrant+men+who+have+sex+with+men+%28MSM%29+in+Beijing%2C+China&rft.au=Song%2C+Yan%3BLi%2C+Xiaoming%3BZhang%2C+Liying%3BLiu%2C+Yingjie%3BJiang%2C+Shulin%3BStanton%2C+Bonita&rft.aulast=Song&rft.aufirst=Yan&rft.date=2012-11-01&rft.volume=71&rft.issue=6&rft.spage=699&rft.isbn=&rft.btitle=&rft.title=Health+education+journal&rft.issn=00178969&rft_id=info:doi/10.1177%2F0017896911422776 LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 8037; 10072; 7931 5421 6091; 5969 11579 11538; 5971; 10739 12228 10919; 11581 3617 6220; 5703 3617 6220; 482 3617 6220; 93 116 30 DO - http://dx.doi.org/10.1177/0017896911422776 ER - TY - JOUR T1 - Rash, hepatotoxicity and hyperbilirubinemia among Kenyan infants born to HIV-infected women receiving triple-antiretroviral drugs for the prevention of mother-to-child HIV transmission. AN - 1112678929; 22772167 AB - We compared adverse events among breast-feeding neonates born to Kenyan mothers receiving triple-antiretroviral therapy, including either nevirapine or nelfinavir. Nevirapine-exposed infants had an absolute increase in the risk of rash but no significant risk differences for hepatotoxicity or high-risk hyperbilirubinemia compared with nelfinavir-exposed infants. From an infant-safety perspective, nevirapine-based regimens given during pregnancy and breast-feeding are viable options where alternatives to breast milk are not safe, affordable or feasible. JF - The Pediatric infectious disease journal AU - Minniear, Timothy D AU - Zeh, Clement AU - Polle, Nicholas AU - Masaba, Rose AU - Peters, Philip J AU - Oyaro, Boaz AU - Akoth, Benta AU - Ndivo, Richard AU - Angira, Frank AU - Mills, Lisa A AU - Thomas, Timothy K AD - Epidemic Intelligence Service and †Division of HIV/AIDS Prevention, CDC, Atlanta, GA, USA. iyo4@cdc.gov Y1 - 2012/11// PY - 2012 DA - November 2012 SP - 1155 EP - 1157 VL - 31 IS - 11 KW - Anti-HIV Agents KW - 0 KW - Nevirapine KW - 99DK7FVK1H KW - Nelfinavir KW - HO3OGH5D7I KW - Index Medicus KW - Nevirapine -- adverse effects KW - Nelfinavir -- adverse effects KW - Aging, Premature KW - Drug Eruptions -- etiology KW - Nevirapine -- therapeutic use KW - Humans KW - Adult KW - Infant, Newborn KW - Drug Eruptions -- pathology KW - Nelfinavir -- therapeutic use KW - Kenya -- epidemiology KW - Female KW - Pregnancy KW - Infectious Disease Transmission, Vertical -- prevention & control KW - Chemical and Drug Induced Liver Injury -- blood KW - Hyperbilirubinemia -- chemically induced KW - Anti-HIV Agents -- therapeutic use KW - Chemical and Drug Induced Liver Injury -- pathology KW - HIV Infections -- drug therapy KW - Anti-HIV Agents -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1112678929?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Pediatric+infectious+disease+journal&rft.atitle=Rash%2C+hepatotoxicity+and+hyperbilirubinemia+among+Kenyan+infants+born+to+HIV-infected+women+receiving+triple-antiretroviral+drugs+for+the+prevention+of+mother-to-child+HIV+transmission.&rft.au=Minniear%2C+Timothy+D%3BZeh%2C+Clement%3BPolle%2C+Nicholas%3BMasaba%2C+Rose%3BPeters%2C+Philip+J%3BOyaro%2C+Boaz%3BAkoth%2C+Benta%3BNdivo%2C+Richard%3BAngira%2C+Frank%3BMills%2C+Lisa+A%3BThomas%2C+Timothy+K&rft.aulast=Minniear&rft.aufirst=Timothy&rft.date=2012-11-01&rft.volume=31&rft.issue=11&rft.spage=1155&rft.isbn=&rft.btitle=&rft.title=The+Pediatric+infectious+disease+journal&rft.issn=1532-0987&rft_id=info:doi/10.1097%2FINF.0b013e318267ef6a LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2013-03-12 N1 - Date created - 2012-10-16 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1097/INF.0b013e318267ef6a ER - TY - CPAPER T1 - Role of emotion dysregulation in sexual risk-taking among African American adolescent girls in juvenile detention T2 - 140th American Public Health Association Annual Meeting and Exposition (APHA 2012) AN - 1313096715; 6157303 JF - 140th American Public Health Association Annual Meeting and Exposition (APHA 2012) AU - Abad, Neetu Y1 - 2012/10/27/ PY - 2012 DA - 2012 Oct 27 KW - Africa KW - Adolescents KW - Ethnic groups KW - Sexual behavior KW - Emotions UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313096715?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=140th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2012%29&rft.atitle=Role+of+emotion+dysregulation+in+sexual+risk-taking+among+African+American+adolescent+girls+in+juvenile+detention&rft.au=Abad%2C+Neetu&rft.aulast=Abad&rft.aufirst=Neetu&rft.date=2012-10-27&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=140th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2012%29&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/140am/webprogram/start.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Determinants of Timely versus Late Postnatal Detection of Infants with Critical Congenital Heart Disease T2 - 140th American Public Health Association Annual Meeting and Exposition (APHA 2012) AN - 1313086483; 6157370 JF - 140th American Public Health Association Annual Meeting and Exposition (APHA 2012) AU - Dawson, April AU - Cassell, Cynthia AU - Peterson, Cora AU - Colarusso, Tiffany AU - Grosse, Scott AU - Tanner, Jean AU - Kirby, Russell AU - Correia, Jane AU - Watkins, Sharon AU - Olney, Richard Y1 - 2012/10/27/ PY - 2012 DA - 2012 Oct 27 KW - Heart diseases KW - Infants KW - Disease detection UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313086483?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=140th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2012%29&rft.atitle=Determinants+of+Timely+versus+Late+Postnatal+Detection+of+Infants+with+Critical+Congenital+Heart+Disease&rft.au=Dawson%2C+April%3BCassell%2C+Cynthia%3BPeterson%2C+Cora%3BColarusso%2C+Tiffany%3BGrosse%2C+Scott%3BTanner%2C+Jean%3BKirby%2C+Russell%3BCorreia%2C+Jane%3BWatkins%2C+Sharon%3BOlney%2C+Richard&rft.aulast=Dawson&rft.aufirst=April&rft.date=2012-10-27&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=140th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2012%29&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/140am/webprogram/start.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Motor Vehicle Safety T2 - 140th American Public Health Association Annual Meeting and Exposition (APHA 2012) AN - 1313085098; 6157504 JF - 140th American Public Health Association Annual Meeting and Exposition (APHA 2012) AU - Dellinger, Ann Y1 - 2012/10/27/ PY - 2012 DA - 2012 Oct 27 KW - Motor vehicles UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313085098?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=140th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2012%29&rft.atitle=Motor+Vehicle+Safety&rft.au=Dellinger%2C+Ann&rft.aulast=Dellinger&rft.aufirst=Ann&rft.date=2012-10-27&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=140th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2012%29&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/140am/webprogram/start.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Putting science into action to prevent violence against children and youth T2 - 140th American Public Health Association Annual Meeting and Exposition (APHA 2012) AN - 1313085002; 6157503 JF - 140th American Public Health Association Annual Meeting and Exposition (APHA 2012) AU - Simon, Thomas Y1 - 2012/10/27/ PY - 2012 DA - 2012 Oct 27 KW - Violence KW - Children KW - Aggression UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313085002?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=140th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2012%29&rft.atitle=Putting+science+into+action+to+prevent+violence+against+children+and+youth&rft.au=Simon%2C+Thomas&rft.aulast=Simon&rft.aufirst=Thomas&rft.date=2012-10-27&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=140th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2012%29&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/140am/webprogram/start.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Association between Severity of Vision Impairment and Falls among People Aged 65 Years and Older Living in the Community: Findings from the BRFSS T2 - 140th American Public Health Association Annual Meeting and Exposition (APHA 2012) AN - 1313084763; 6158521 JF - 140th American Public Health Association Annual Meeting and Exposition (APHA 2012) AU - Crews, John Y1 - 2012/10/27/ PY - 2012 DA - 2012 Oct 27 KW - Vision UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313084763?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=140th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2012%29&rft.atitle=Association+between+Severity+of+Vision+Impairment+and+Falls+among+People+Aged+65+Years+and+Older+Living+in+the+Community%3A+Findings+from+the+BRFSS&rft.au=Crews%2C+John&rft.aulast=Crews&rft.aufirst=John&rft.date=2012-10-27&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=140th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2012%29&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/140am/webprogram/start.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Annual Exploration of Injury and Emergency Health Data Issues T2 - 140th American Public Health Association Annual Meeting and Exposition (APHA 2012) AN - 1313082657; 6155861 JF - 140th American Public Health Association Annual Meeting and Exposition (APHA 2012) AU - Annest, Joseph AU - Hedegaard, Holly AU - Warner, Margaret AU - Cook, Larry Y1 - 2012/10/27/ PY - 2012 DA - 2012 Oct 27 KW - Injuries KW - Data processing KW - Emergencies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313082657?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=140th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2012%29&rft.atitle=Annual+Exploration+of+Injury+and+Emergency+Health+Data+Issues&rft.au=Annest%2C+Joseph%3BHedegaard%2C+Holly%3BWarner%2C+Margaret%3BCook%2C+Larry&rft.aulast=Annest&rft.aufirst=Joseph&rft.date=2012-10-27&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=140th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2012%29&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/140am/webprogram/start.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Social determinants of health and disability status: Double jeopardy for health disparities T2 - 140th American Public Health Association Annual Meeting and Exposition (APHA 2012) AN - 1313074984; 6158753 JF - 140th American Public Health Association Annual Meeting and Exposition (APHA 2012) AU - Campbell, Vincent AU - Courtney-Long, Elizabeth Y1 - 2012/10/27/ PY - 2012 DA - 2012 Oct 27 KW - Disabilities UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313074984?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=140th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2012%29&rft.atitle=Social+determinants+of+health+and+disability+status%3A+Double+jeopardy+for+health+disparities&rft.au=Campbell%2C+Vincent%3BCourtney-Long%2C+Elizabeth&rft.aulast=Campbell&rft.aufirst=Vincent&rft.date=2012-10-27&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=140th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2012%29&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/140am/webprogram/start.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - "Learn the Signs. Act Early" CDC's Public Health Approach to Early Identification T2 - 140th American Public Health Association Annual Meeting and Exposition (APHA 2012) AN - 1313053995; 6158663 JF - 140th American Public Health Association Annual Meeting and Exposition (APHA 2012) AU - Smith, Donna Y1 - 2012/10/27/ PY - 2012 DA - 2012 Oct 27 KW - Public health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313053995?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=140th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2012%29&rft.atitle=%22Learn+the+Signs.+Act+Early%22+CDC%27s+Public+Health+Approach+to+Early+Identification&rft.au=Smith%2C+Donna&rft.aulast=Smith&rft.aufirst=Donna&rft.date=2012-10-27&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=140th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2012%29&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/140am/webprogram/start.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Healthy Aging - Introduction T2 - 140th American Public Health Association Annual Meeting and Exposition (APHA 2012) AN - 1313032191; 6157808 JF - 140th American Public Health Association Annual Meeting and Exposition (APHA 2012) AU - Anderson, Lynda Y1 - 2012/10/27/ PY - 2012 DA - 2012 Oct 27 KW - Aging UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313032191?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=140th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2012%29&rft.atitle=Healthy+Aging+-+Introduction&rft.au=Anderson%2C+Lynda&rft.aulast=Anderson&rft.aufirst=Lynda&rft.date=2012-10-27&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=140th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2012%29&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/140am/webprogram/start.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - New Directions to Healthy Aging in the 21st Century T2 - 140th American Public Health Association Annual Meeting and Exposition (APHA 2012) AN - 1313032158; 6157807 JF - 140th American Public Health Association Annual Meeting and Exposition (APHA 2012) AU - Anderson, Lynda Y1 - 2012/10/27/ PY - 2012 DA - 2012 Oct 27 KW - Aging UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313032158?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=140th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2012%29&rft.atitle=New+Directions+to+Healthy+Aging+in+the+21st+Century&rft.au=Anderson%2C+Lynda&rft.aulast=Anderson&rft.aufirst=Lynda&rft.date=2012-10-27&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=140th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2012%29&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/140am/webprogram/start.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - CDC progress on male reproductive health and men's health T2 - 140th American Public Health Association Annual Meeting and Exposition (APHA 2012) AN - 1313021500; 6157388 JF - 140th American Public Health Association Annual Meeting and Exposition (APHA 2012) AU - Warner, Lee Y1 - 2012/10/27/ PY - 2012 DA - 2012 Oct 27 KW - Reproduction UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313021500?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=140th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2012%29&rft.atitle=CDC+progress+on+male+reproductive+health+and+men%27s+health&rft.au=Warner%2C+Lee&rft.aulast=Warner&rft.aufirst=Lee&rft.date=2012-10-27&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=140th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2012%29&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/140am/webprogram/start.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Depression and Vision Loss Are Associated in Young, Middle-aged, and Older Adults in the United States, NHANES 2005-2008 T2 - 140th American Public Health Association Annual Meeting and Exposition (APHA 2012) AN - 1313020593; 6155650 JF - 140th American Public Health Association Annual Meeting and Exposition (APHA 2012) AU - Zhang, Xinzhi AU - Bullard, Kai AU - Cotch, Mary AU - Rovner, Barry AU - McGwin, Gerald AU - Owsley, Cynthia AU - Barker, Lawrence AU - Crews, John AU - Saaddine, Jinan Y1 - 2012/10/27/ PY - 2012 DA - 2012 Oct 27 KW - USA KW - Vision KW - Depression UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313020593?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=140th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2012%29&rft.atitle=Depression+and+Vision+Loss+Are+Associated+in+Young%2C+Middle-aged%2C+and+Older+Adults+in+the+United+States%2C+NHANES+2005-2008&rft.au=Zhang%2C+Xinzhi%3BBullard%2C+Kai%3BCotch%2C+Mary%3BRovner%2C+Barry%3BMcGwin%2C+Gerald%3BOwsley%2C+Cynthia%3BBarker%2C+Lawrence%3BCrews%2C+John%3BSaaddine%2C+Jinan&rft.aulast=Zhang&rft.aufirst=Xinzhi&rft.date=2012-10-27&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=140th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2012%29&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/140am/webprogram/start.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Severity of Vision Impairment and Health-Related Quality of Life among Community Residents aged >=40 Years: Findings from the 2006-2010 Behavioral Risk Factor Surveillance System T2 - 140th American Public Health Association Annual Meeting and Exposition (APHA 2012) AN - 1313020559; 6155649 JF - 140th American Public Health Association Annual Meeting and Exposition (APHA 2012) AU - Crews, John AU - Chou, Chiu-Fang AU - Zhang, Xinzhi AU - Zack, Matthew AU - Saaddine, Jinan Y1 - 2012/10/27/ PY - 2012 DA - 2012 Oct 27 KW - Vision KW - Quality of life KW - Risk factors KW - Biological surveys UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313020559?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=140th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2012%29&rft.atitle=Severity+of+Vision+Impairment+and+Health-Related+Quality+of+Life+among+Community+Residents+aged+%26gt%3B%3D40+Years%3A+Findings+from+the+2006-2010+Behavioral+Risk+Factor+Surveillance+System&rft.au=Crews%2C+John%3BChou%2C+Chiu-Fang%3BZhang%2C+Xinzhi%3BZack%2C+Matthew%3BSaaddine%2C+Jinan&rft.aulast=Crews&rft.aufirst=John&rft.date=2012-10-27&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=140th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2012%29&rft.issn=&rft_id=info:doi/ L2 - https://apha.confex.com/apha/140am/webprogram/start.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - JOUR T1 - A STUDY ON THE EPIDEMIOLOGICAL CHARACTERISTICS OF OVERWEIGHT AND OBESITY AND ITS RELATIONSHIP WITH THE HYPERTENSION AMONG ADULT RESIDENTS IN SHANDONG PROVINCE AN - 1680438774; 20344704 AB - ObjectivesTo describe the epidemiological distribution of overweight and obesity and explore its relationship with hypertension among adult residents in Shandong province.MethodsA cross-sectional survey was conducted among 15350 permanent residents aged between 18-69years old with stratified multistage sampling during July to August 2011, in Shandong province. All participants were interviewed with a standard questionnaire. Anthropometric indicators including height, weight and waist circumference (WC) were measured.ResultsThe general prevalence rate of overweight, obesity and central obesity was 32.77%, 16.60% and 50.33% among adult residents in Shandong province. There is no difference of the epidemiological distribution between different groups classified by gender, region and city. The average levels of blood pressure gradually increased with the increasing of BMI and WC, while the rate of hypertension also increased. The prevalence rate of hypertension was 8.56%, 13.42% and 28.20% among normal BMI, overweight and obesity people. After adjusting age and gender, the prevalence rates were 2.34 times and 5.92 times higher among overweight and obesity people than those among normal BMI people.ConclusionsNearly half of Shandong adult residents are overweight or obesity. Overweight and obesity have become important public health problems in Shandong province and they are major risk factors to cause hypertension. Health education and health promotion should be strengthened to prevent and control overweight and obesity. JF - Heart AU - Jing, Dong AU - Xiaolei, Guo AU - Jiyu, Zhang AU - Junli, Tang AU - Zilong, Lu AU - Jie, Chu AU - Aiqiang, Xu AD - Shandong Center for Disease Control and Prevention Y1 - 2012/10// PY - 2012 DA - Oct 2012 SP - E156 PB - British Medical Association, BMA House Square London WC1H 9JP United Kingdom VL - 98 IS - Suppl 2 SN - 1468-201X, 1468-201X KW - Physical Education Index KW - Obesity KW - Preventive health KW - Body mass KW - Gender KW - Surveys KW - Adults KW - Health (education) KW - Hypertension KW - Public health KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1680438774?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Heart&rft.atitle=A+STUDY+ON+THE+EPIDEMIOLOGICAL+CHARACTERISTICS+OF+OVERWEIGHT+AND+OBESITY+AND+ITS+RELATIONSHIP+WITH+THE+HYPERTENSION+AMONG+ADULT+RESIDENTS+IN+SHANDONG+PROVINCE&rft.au=Jing%2C+Dong%3BXiaolei%2C+Guo%3BJiyu%2C+Zhang%3BJunli%2C+Tang%3BZilong%2C+Lu%3BJie%2C+Chu%3BAiqiang%2C+Xu&rft.aulast=Jing&rft.aufirst=Dong&rft.date=2012-10-01&rft.volume=98&rft.issue=Suppl+2&rft.spage=E156&rft.isbn=&rft.btitle=&rft.title=Heart&rft.issn=1468201X&rft_id=info:doi/10.1136%2Fheartjnl-2012-302920h.4 LA - English DB - Physical Education Index N1 - Date revised - 2015-05-01 N1 - Last updated - 2015-06-12 N1 - SubjectsTermNotLitGenreText - Obesity; Preventive health; Body mass; Gender; Surveys; Adults; Health (education); Public health; Hypertension DO - http://dx.doi.org/10.1136/heartjnl-2012-302920h.4 ER - TY - JOUR T1 - Coordination Costs for School-Located Influenza Vaccination Clinics, Maine, 2009 H1N1 Pandemic AN - 1551640021; 20379339 AB - School nurses played a key role in Maine's school-located influenza vaccination (SLV) clinics during the 2009-2010 pandemic season. The objective of this study was to determine, from the school district perspective, the labor hours and costs associated with outside-clinic coordination activities (OCA). The authors defined OCA as labor hours spent by staff outside of clinic operations. The authors surveyed a convenience sample of 10 school nurses from nine school districts. Eight nurses responded to the survey, representing seven districts, 45 schools and 84 SLV clinics that provided a total of 22,596 vaccine doses (H1N1 and seasonal combined) to children and adolescents. The mean total OCA time per clinic was 69 hours: out of total hours, 22 (36%) were spent outside regular clinic operation time. The authors estimated the mean cost of OCA to be $15.36 per dose. Survey respondents reported that costs would be lower during non-pandemic seasons and as schools become more proficient at planning clinics. JF - The Journal of School Nursing AU - Asay, Garrett RBeeler AU - Cho, Bo-Hyun AU - Lorick, Suchita A AU - Tipton, Meredith L AU - Dube, Nancy L AU - Messonnier, Mark L AD - Health Services Research and Evaluation Branch, Immunization Services Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USAc, hrp9@cdc.gov Y1 - 2012/10// PY - 2012 DA - Oct 2012 SP - 328 EP - 335 VL - 28 IS - 5 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - influenza KW - vaccination KW - pandemic KW - H1N1 KW - school nurse KW - economic evaluation KW - school-located vaccination clinics KW - Adolescence KW - Children KW - Vaccination KW - Medical personnel KW - Influenza KW - pandemics KW - Schools KW - Sulfur dioxide KW - Combined vaccines KW - Nursing KW - USA, Maine KW - Vaccines KW - Seasonal variations KW - Adolescents KW - H 4000:Food and Drugs KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1551640021?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+School+Nursing&rft.atitle=Coordination+Costs+for+School-Located+Influenza+Vaccination+Clinics%2C+Maine%2C+2009+H1N1+Pandemic&rft.au=Asay%2C+Garrett+RBeeler%3BCho%2C+Bo-Hyun%3BLorick%2C+Suchita+A%3BTipton%2C+Meredith+L%3BDube%2C+Nancy+L%3BMessonnier%2C+Mark+L&rft.aulast=Asay&rft.aufirst=Garrett&rft.date=2012-10-01&rft.volume=28&rft.issue=5&rft.spage=328&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+School+Nursing&rft.issn=&rft_id=info:doi/10.1177%2F1059840512448676 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-08-01 N1 - Last updated - 2014-10-02 N1 - SubjectsTermNotLitGenreText - Influenza; pandemics; Combined vaccines; Nursing; Adolescence; Children; Vaccination; Sulfur dioxide; Schools; Vaccines; Seasonal variations; Adolescents; Medical personnel; USA, Maine DO - http://dx.doi.org/10.1177/1059840512448676 ER - TY - JOUR T1 - Costs of School-Located Influenza Vaccination Clinics in Maine During the 2009-2010 H1N1 Pandemic AN - 1551637795; 20379342 AB - This study retrospectively estimated costs for a convenience sample of school-located vaccination (SLV) clinics conducted in Maine during the 2009-2010 influenza season. Surveys were developed to capture the cost of labor including unpaid volunteers as well as supplies and materials used in SLV clinics. Six nurses from different school districts completed a clinic day survey on staff time; four of the six also provided data for materials and supplies. For all clinics, average per-dose labor cost was estimated at $5.95. Average per-dose material cost, excluding vaccine, was $5.76. From the four complete clinic survey responses, total per-dose cost was estimated to be an average of $13.51 (range = $4.91-$32.39). Use of donated materials and uncompensated volunteer staff could substantially reduce per-dose cost. Average per-dose cost could also be lowered by increasing the number of doses administered in a clinic. JF - The Journal of School Nursing AU - Cho, Bo-Hyun AU - Asay, Garrett RBeeler AU - Lorick, Suchita A AU - Tipton, Meredith L AU - Dube, Nancy L AU - Messonnier, Mark L AD - Carter Consulting Inc, Atlanta, GA, USA, bcho@cdc.gov Y1 - 2012/10// PY - 2012 DA - Oct 2012 SP - 336 EP - 343 VL - 28 IS - 5 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - influenza vaccination KW - 2009 H1N1 KW - pandemic KW - influenza KW - school nurse KW - cost evaluation KW - school-located vaccination clinics KW - Labor costs KW - Data processing KW - Vaccination KW - Medical personnel KW - Influenza KW - pandemics KW - Schools KW - Nursing KW - USA, Maine KW - Vaccines KW - H 4000:Food and Drugs KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1551637795?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+School+Nursing&rft.atitle=Costs+of+School-Located+Influenza+Vaccination+Clinics+in+Maine+During+the+2009-2010+H1N1+Pandemic&rft.au=Cho%2C+Bo-Hyun%3BAsay%2C+Garrett+RBeeler%3BLorick%2C+Suchita+A%3BTipton%2C+Meredith+L%3BDube%2C+Nancy+L%3BMessonnier%2C+Mark+L&rft.aulast=Cho&rft.aufirst=Bo-Hyun&rft.date=2012-10-01&rft.volume=28&rft.issue=5&rft.spage=336&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+School+Nursing&rft.issn=&rft_id=info:doi/10.1177%2F1059840512457049 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-08-01 N1 - Last updated - 2014-10-02 N1 - SubjectsTermNotLitGenreText - Influenza; pandemics; Data processing; Nursing; Vaccines; Vaccination; Labor costs; Schools; Medical personnel; USA, Maine DO - http://dx.doi.org/10.1177/1059840512457049 ER - TY - JOUR T1 - Fifty Communities Putting Prevention to Work: Accelerating Chronic Disease Prevention Through Policy, Systems and Environmental Change AN - 1500780981; 17156450 AB - The burden of preventable chronic diseases is straining our nation's health and economy. Diseases caused by obesity and tobacco use account for the largest portions of this preventable burden. CDC funded 50 communities in 2010 to implement policy, systems, and environmental (PSE) interventions in a 2-year initiative. Funded communities developed PSE plans to reduce obesity, tobacco use, and second-hand smoke exposure for their combined 55 million residents. Community outcome objectives and milestones were categorized by PSE interventions as they related to media, access, promotion, pricing, and social support. Communities estimated population reach based on their jurisdiction's census data and target populations. The average proportion of each community's population that was reached was calculated for each intervention category. Outcome objectives that were achieved within 12 months of program initiation were identified from routine program records. The average proportion of a community's jurisdictional population reached by a specific intervention varied across interventions. Mean population reach for obesity-prevention interventions was estimated at 35%, with 14 (26%) interventions covering over 50% of the jurisdictional populations. For tobacco prevention, mean population reach was estimated at 67%, with 16 (84%) interventions covering more than 50% of the jurisdictional populations. Within 12 months, communities advanced over one-third of their obesity and tobacco-use prevention strategies. Tobacco interventions appeared to have higher potential population reach than obesity interventions within this initiative. Findings on the progress and potential reach of this major initiative may help inform future chronic disease prevention efforts. JF - Journal of Community Health AU - Bunnell, Rebecca AU - O'Neil, Dara AU - Soler, Robin AU - Payne, Rebecca AU - Giles, Wayne H AU - Collins, Janet AU - Bauer, Ursula AD - Division of Community Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Hwy., MS-K45, Atlanta, GA, 30341, USA, rrb7@cdc.gov Y1 - 2012/10// PY - 2012 DA - Oct 2012 SP - 1081 EP - 1090 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 37 IS - 5 SN - 0094-5145, 0094-5145 KW - Environment Abstracts KW - Census KW - Intervention KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1500780981?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Community+Health&rft.atitle=Fifty+Communities+Putting+Prevention+to+Work%3A+Accelerating+Chronic+Disease+Prevention+Through+Policy%2C+Systems+and+Environmental+Change&rft.au=Bunnell%2C+Rebecca%3BO%27Neil%2C+Dara%3BSoler%2C+Robin%3BPayne%2C+Rebecca%3BGiles%2C+Wayne+H%3BCollins%2C+Janet%3BBauer%2C+Ursula&rft.aulast=Bunnell&rft.aufirst=Rebecca&rft.date=2012-10-01&rft.volume=37&rft.issue=5&rft.spage=1081&rft.isbn=&rft.btitle=&rft.title=Journal+of+Community+Health&rft.issn=00945145&rft_id=info:doi/10.1007%2Fs10900-012-9542-3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-02-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Intervention DO - http://dx.doi.org/10.1007/s10900-012-9542-3 ER - TY - JOUR T1 - The Study to Explore Early Development (SEED): A Multisite Epidemiologic Study of Autism by the Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) Network AN - 1323338064; 201304939 AB - The Study to Explore Early Development (SEED), a multisite investigation addressing knowledge gaps in autism phenotype and etiology, aims to: (1) characterize the autism behavioral phenotype and associated developmental, medical, and behavioral conditions and (2) investigate genetic and environmental risks with emphasis on immunologic, hormonal, gastrointestinal, and sociodemographic characteristics. SEED uses a case-control design with population-based ascertainment of children aged 2-5 years with an autism spectrum disorder (ASD) and children in two control groups-one from the general population and one with non-ASD developmental problems. Data from parent-completed questionnaires, interviews, clinical evaluations, biospecimen sampling, and medical record abstraction focus on the prenatal and early postnatal periods. SEED is a valuable resource for testing hypotheses regarding ASD characteristics and causes. Adapted from the source document. JF - Journal of Autism and Developmental Disorders AU - Schendel, Diana E AU - DiGuiseppi, Carolyn AU - Croen, Lisa A AU - Fallin, M Daniele AU - Reed, Philip L AU - Schieve, Laura A AU - Wiggins, Lisa D AU - Daniels, Julie AU - Grether, Judith AU - Levy, Susan E AU - Miller, Lisa AU - Newschaffer, Craig AU - Pinto-Martin, Jennifer AU - Robinson, Cordelia AU - Windham, Gayle C AU - Alexander, Aimee AU - Aylsworth, Arthur S AU - Bernal, Pilar AU - Bonner, Joseph D AU - Blaskey, Lisa AU - Bradley, Chyrise AU - Collins, Jack AU - Ferretti, Casara J AU - Farzadegan, Homayoon AU - Giarelli, Ellen AU - Harvey, Marques AU - Hepburn, Susan AU - Herr, Matthew AU - Kaparich, Kristina AU - Landa, Rebecca AU - Lee, Li-Ching AU - Levenseller, Brooke AU - Meyerer, Stacey AU - Rahbar, Mohammad H AU - Ratchford, Andria AU - Reynolds, Ann AU - Rosenberg, Steven AU - Rusyniak, Julie AU - Shapira, Stuart K AU - Smith, Karen AU - Souders, Margaret AU - Thompson, Patrick Aaron AU - Young, Lisa AU - Yeargin-Allsopp, Marshalyn AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 1600 Clifton Road, MS E-86, Atlanta, GA, 30333, USA dschendel@cdc.gov Y1 - 2012/10// PY - 2012 DA - October 2012 SP - 2121 EP - 2140 PB - Springer, Dordrecht The Netherlands VL - 42 IS - 10 SN - 0162-3257, 0162-3257 KW - Seeds KW - Antenatal KW - Environmental aspects KW - Autistic children KW - Phenotypes KW - Autistic spectrum disorders KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1323338064?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Autism+and+Developmental+Disorders&rft.atitle=The+Study+to+Explore+Early+Development+%28SEED%29%3A+A+Multisite+Epidemiologic+Study+of+Autism+by+the+Centers+for+Autism+and+Developmental+Disabilities+Research+and+Epidemiology+%28CADDRE%29+Network&rft.au=Schendel%2C+Diana+E%3BDiGuiseppi%2C+Carolyn%3BCroen%2C+Lisa+A%3BFallin%2C+M+Daniele%3BReed%2C+Philip+L%3BSchieve%2C+Laura+A%3BWiggins%2C+Lisa+D%3BDaniels%2C+Julie%3BGrether%2C+Judith%3BLevy%2C+Susan+E%3BMiller%2C+Lisa%3BNewschaffer%2C+Craig%3BPinto-Martin%2C+Jennifer%3BRobinson%2C+Cordelia%3BWindham%2C+Gayle+C%3BAlexander%2C+Aimee%3BAylsworth%2C+Arthur+S%3BBernal%2C+Pilar%3BBonner%2C+Joseph+D%3BBlaskey%2C+Lisa%3BBradley%2C+Chyrise%3BCollins%2C+Jack%3BFerretti%2C+Casara+J%3BFarzadegan%2C+Homayoon%3BGiarelli%2C+Ellen%3BHarvey%2C+Marques%3BHepburn%2C+Susan%3BHerr%2C+Matthew%3BKaparich%2C+Kristina%3BLanda%2C+Rebecca%3BLee%2C+Li-Ching%3BLevenseller%2C+Brooke%3BMeyerer%2C+Stacey%3BRahbar%2C+Mohammad+H%3BRatchford%2C+Andria%3BReynolds%2C+Ann%3BRosenberg%2C+Steven%3BRusyniak%2C+Julie%3BShapira%2C+Stuart+K%3BSmith%2C+Karen%3BSouders%2C+Margaret%3BThompson%2C+Patrick+Aaron%3BYoung%2C+Lisa%3BYeargin-Allsopp%2C+Marshalyn&rft.aulast=Schendel&rft.aufirst=Diana&rft.date=2012-10-01&rft.volume=42&rft.issue=10&rft.spage=2121&rft.isbn=&rft.btitle=&rft.title=Journal+of+Autism+and+Developmental+Disorders&rft.issn=01623257&rft_id=info:doi/10.1007%2Fs10803-012-1461-8 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2013-04-01 N1 - Last updated - 2016-09-27 N1 - CODEN - JADDDQ N1 - SubjectsTermNotLitGenreText - Autistic spectrum disorders; Seeds; Phenotypes; Autistic children; Environmental aspects; Antenatal DO - http://dx.doi.org/10.1007/s10803-012-1461-8 ER - TY - JOUR T1 - Effect of policy changes on cigarette sales: the case of Turkey AN - 1284077646; 2011-342697 AB - Background: In 1996, Turkey made tobacco control a health priority. The tobacco control effort was extended in July 2009 with the expansion of the smoke-free law to include all enclosed workplaces and public places and, in January 2010, with a 20% increase in the Special Consumption Tax on Tobacco. Methods: Sales data were averaged, by month, for the period January 2005 through June 2009 to establish an 'expected' monthly sales pattern. This was the period when no new tobacco control measures were implemented. The overall monthly average was then calculated for the same period. The expected monthly sales pattern was then graphed against the overall monthly sales average to delineate a seasonal sales pattern that was used to evaluate the divergence of actual monthly sales from the 'expected' pattern. Results: A distinct seasonal pattern was found with sales above average from May through August. Comparison of actual cigarette sales to the 'expected' monthly sales pattern following the implementation of the expanded smoke-free law in July resulted in a 5.2% decrease. Cigarettes sales decreased by 13.6% following the January 2010 Special Consumption Tax. Since the implementation of the expanded smoke-free law in July 2009 and the tax increase in January 2010, cigarette sales in Turkey decreased by 10.7%. Conclusion: The effect of recent Turkish tobacco control policies could contribute to a reduction in the number of premature deaths related to tobacco use. Evidence has shown that periodic tax increases and strong enforcement of all tobacco control policies are essential to further decrease tobacco consumption. Adapted from the source document. JF - European Journal of Public Health AU - Warren, Charles W AU - Erguder, Toker AU - Lee, Juliette AU - Lea, Veronica AU - Sauer, Ann Goding AU - Jones, Nathan R AU - Bilir, Nazmi AD - Centers for Disease Control and Prevention, Atlanta GA, USA wwarren@cdc.gov Y1 - 2012/10// PY - 2012 DA - October 2012 SP - 712 EP - 716 PB - Oxford University Press. UK VL - 22 IS - 5 SN - 1101-1262, 1101-1262 KW - Health conditions and policy - Health and health policy KW - Social conditions and policy - Drinking, smoking, and drug addiction KW - Law and ethics - Law and jurisprudence KW - Economic conditions and policy - Consumers and consumption KW - Business and service sector - Business operations, practices, and workplaces KW - Smoking KW - Consumption KW - Turkey KW - Law KW - Health policy KW - Workplaces KW - Public health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1284077646?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=European+Journal+of+Public+Health&rft.atitle=Effect+of+policy+changes+on+cigarette+sales%3A+the+case+of+Turkey&rft.au=Warren%2C+Charles+W%3BErguder%2C+Toker%3BLee%2C+Juliette%3BLea%2C+Veronica%3BSauer%2C+Ann+Goding%3BJones%2C+Nathan+R%3BBilir%2C+Nazmi&rft.aulast=Warren&rft.aufirst=Charles&rft.date=2012-10-01&rft.volume=22&rft.issue=5&rft.spage=712&rft.isbn=&rft.btitle=&rft.title=European+Journal+of+Public+Health&rft.issn=11011262&rft_id=info:doi/10.1093%2Feurpub%2Fckr157 LA - English DB - PAIS Index N1 - Date revised - 2013-02-01 N1 - Last updated - 2016-09-28 N1 - CODEN - EJPHF6 N1 - SubjectsTermNotLitGenreText - Public health; Health policy; Smoking; Law; Consumption; Turkey; Workplaces DO - http://dx.doi.org/10.1093/eurpub/ckr157 ER - TY - JOUR T1 - 2011: The year in review. Part II: Tuberculosis and lung disease AN - 1171870644; 17342648 AB - IN THIS YEAR-IN-REVIEW ARTICLE, we review 52 of 55 articles published on tuberculosis (TB) in the International Journal of Tuberculosis and Lung Disease from August through December 2011, complementing the 104 summarized by Chang and Nuermberger, super(1) and using the same categories (Table 1). We also summarize 33 of 36 non-TB articles for the entire year (Table 2). JF - International Journal of Tuberculosis and Lung Disease AU - Iademarco, M F AU - Koh, W J AD - Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, GA, USA, mai9@cdc.gov Y1 - 2012/10// PY - 2012 DA - Oct 2012 SP - 1291 EP - 1299 PB - International Union Against Tuberculosis and Lung Disease VL - 16 IS - 10 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology KW - Mycobacterium KW - Reviews KW - Lung diseases KW - Tuberculosis KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1171870644?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=2011%3A+The+year+in+review.+Part+II%3A+Tuberculosis+and+lung+disease&rft.au=Iademarco%2C+M+F%3BKoh%2C+W+J&rft.aulast=Iademarco&rft.aufirst=M&rft.date=2012-10-01&rft.volume=16&rft.issue=10&rft.spage=1291&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-11-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Reviews; Lung diseases; Tuberculosis; Mycobacterium ER - TY - JOUR T1 - Associations between maternal prepregnancy body mass index and child neurodevelopment at 2 years of age AN - 1113218896; 17253624 AB - Objective: Both underweight and obese mothers have an increased risk for adverse offspring outcomes. Few studies have examined the association between prepregnancy body mass index (BMI) and children's neurodevelopment.Subjects:We used data from the nationally representative Early Childhood Longitudinal Study-Birth Cohort (ECLS-B; n=6850). Children were classified according to their mother's prepregnancy BMI (kg m super(-2)) status: underweight (BMI 1 s.d.) mental or motor development, relative to children of normal weight mothers. Results: Compared with children of normal weight mothers, MDI scores were lower among children of mothers of all other prepregnancy BMI categories, with the greatest adjusted difference among children of class II and III obese mothers (-2.13 (95% CI -3.32, -0.93)). The adjusted risk of delayed mental development was increased among children of underweight (risk ratio (RR) 1.36 (95% CI 1.04, 1.78)) and class II and III obese (RR 1.38 (95% CI 1.03, 1.84)) mothers. Children's PDI scores or motor delay did not differ by maternal prepregnancy BMI. Conclusion: In this nationally representative sample of 2-year-old US children, low and very-high maternal prepregnancy BMI were associated with increased risk of delayed mental development but not motor development. JF - International Journal of Obesity AU - Hinkle, S N AU - Schieve, L A AU - Stein, A D AU - Swan, D W AU - Ramakrishnan, U AU - Sharma, A J AD - 1] Nutrition and Health Sciences, Division of Biological and Biomedical Sciences, Emory University, Atlanta, GA, USA [2] Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA Y1 - 2012/10// PY - 2012 DA - Oct 2012 SP - 1312 EP - 1319 PB - Nature Publishing Group, The Macmillan Building London N1 9XW United Kingdom VL - 36 IS - 10 SN - 0307-0565, 0307-0565 KW - Physical Education Index; CSA Neurosciences Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - Obesity KW - Age KW - Body mass KW - Underweight KW - Offspring KW - Children KW - Body weight KW - Weight KW - Objectives KW - Progeny KW - Body mass index KW - Motor development KW - Mental development KW - Infants KW - N3 11003:Developmental neuroscience KW - R2 23060:Medical and environmental health KW - H 12000:Epidemiology and Public Health KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1113218896?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Obesity&rft.atitle=Associations+between+maternal+prepregnancy+body+mass+index+and+child+neurodevelopment+at+2+years+of+age&rft.au=Hinkle%2C+S+N%3BSchieve%2C+L+A%3BStein%2C+A+D%3BSwan%2C+D+W%3BRamakrishnan%2C+U%3BSharma%2C+A+J&rft.aulast=Hinkle&rft.aufirst=S&rft.date=2012-10-01&rft.volume=36&rft.issue=10&rft.spage=1312&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Obesity&rft.issn=03070565&rft_id=info:doi/10.1038%2Fijo.2012.143 LA - English DB - Physical Education Index; ProQuest Environmental Science Collection N1 - Date revised - 2012-10-01 N1 - Last updated - 2013-08-12 N1 - SubjectsTermNotLitGenreText - Obesity; Age; Weight; Objectives; Body mass; Children; Motor development; Body weight; Progeny; Underweight; Body mass index; Mental development; Infants; Offspring DO - http://dx.doi.org/10.1038/ijo.2012.143 ER - TY - JOUR T1 - Preventing maritime transfer of toxigenic Vibrio cholerae. AN - 1081435750; 23017338 AB - Organisms, including Vibrio cholerae, can be transferred between harbors in the ballast water of ships. Zones in the Caribbean region where distance from shore and water depth meet International Maritime Organization guidelines for ballast water exchange are extremely limited. Use of ballast water treatment systems could mitigate the risk for organism transfer. JF - Emerging infectious diseases AU - Cohen, Nicole J AU - Slaten, Douglas D AU - Marano, Nina AU - Tappero, Jordan W AU - Wellman, Michael AU - Albert, Ryan J AU - Hill, Vincent R AU - Espey, David AU - Handzel, Thomas AU - Henry, Ariel AU - Tauxe, Robert V AD - Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. hei1@cdc.gov Y1 - 2012/10// PY - 2012 DA - October 2012 SP - 1680 EP - 1682 VL - 18 IS - 10 KW - DNA, Bacterial KW - 0 KW - Cholera Toxin KW - 9012-63-9 KW - Index Medicus KW - Virulence KW - Haiti KW - Cholera -- transmission KW - DNA, Bacterial -- genetics KW - Cholera -- prevention & control KW - Waste Disposal, Fluid -- methods KW - Caribbean Region KW - Ships KW - Vibrio cholerae -- genetics KW - Vibrio cholerae -- pathogenicity KW - Vibrio cholerae -- isolation & purification KW - Seawater -- microbiology KW - Water Microbiology KW - Environmental Monitoring -- methods KW - Cholera Toxin -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1081435750?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Emerging+infectious+diseases&rft.atitle=Preventing+maritime+transfer+of+toxigenic+Vibrio+cholerae.&rft.au=Cohen%2C+Nicole+J%3BSlaten%2C+Douglas+D%3BMarano%2C+Nina%3BTappero%2C+Jordan+W%3BWellman%2C+Michael%3BAlbert%2C+Ryan+J%3BHill%2C+Vincent+R%3BEspey%2C+David%3BHandzel%2C+Thomas%3BHenry%2C+Ariel%3BTauxe%2C+Robert+V&rft.aulast=Cohen&rft.aufirst=Nicole&rft.date=2012-10-01&rft.volume=18&rft.issue=10&rft.spage=1680&rft.isbn=&rft.btitle=&rft.title=Emerging+infectious+diseases&rft.issn=1080-6059&rft_id=info:doi/10.3201%2Feid1810.120676 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2013-02-19 N1 - Date created - 2012-09-28 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Nature. 2000 Nov 2;408(6808):49-50 [11081499] MMWR Morb Mortal Wkly Rep. 1993 Feb 12;42(5):91-3 [8429813] Emerg Infect Dis. 2011 Nov;17(11):2147-50 [22099121] Int J Environ Res Public Health. 2010 Oct;7(10):3657-703 [21139855] Emerg Infect Dis. 2011 Nov;17(11):2087-93 [22099111] Appl Environ Microbiol. 1994 Jul;60(7):2597-601 [8074532] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.3201/eid1810.120676 ER - TY - JOUR T1 - The Burden and Severity of Illness Due to 2009 Pandemic Influenza A (H1N1) in a Large US City During the Late Summer and Early Fall of 2009 AN - 1125237337; 17317169 AB - In estimates of illness severity from the spring wave of the 2009 influenza A (H1N1) pandemic, reported case fatality proportions were less than 0.05%. In prior pandemics, subsequent waves of illness were associated with higher mortality. The authors evaluated the burden of the pandemic H1N1 (pH1N1) outbreak in metropolitan Atlanta, Georgia, in the fall of 2009, when increased influenza activity heralded the second wave of the pandemic in the United States. Using data from a community survey, existing surveillance systems, public health laboratories, and local hospitals, they estimated numbers of pH1N1-associated illnesses, emergency department (ED) visits, hospitalizations, intensive care unit (ICU) admissions, and deaths occurring in metropolitan Atlanta during the period August 16, 2009-September 26, 2009. The authors estimated 132,140 pediatric and 132,110 adult symptomatic cases of pH1N1 in metropolitan Atlanta during the investigation time frame. Among children, these cases were associated with 4,560 ED visits, 190 hospitalizations, 51 ICU admissions, and 4 deaths. Among adults, they were associated with 1,130 ED visits, 590 hospitalizations, 140 ICU admissions, and 63 deaths. The combined symptomatic case hospitalization proportion, case ICU admission proportion, and case fatality proportion were 0.281%, 0.069%, and 0.024%, respectively. Influenza burden can be estimated using existing data and local surveys. The increased severity reported for subsequent waves in past pandemics was not evident in this investigation. Nevertheless, the second pH1N1 pandemic wave led to substantial numbers of ED visits, hospitalizations, and deaths in metropolitan Atlanta. JF - American Journal of Epidemiology AU - Doshi, Saumil S AU - Stauffer, Kendra E AU - Parker Fiebelkorn, Amy AU - Lafond, Kathryn E AU - Davidson, Heidi A AU - Apostolou, Andria AU - Taylor, Thomas H AU - Smith, Wendy AU - Karcz, Adam N AU - Watson, JRenee AU - Openo, Kyle P AU - Brooks, Joy G AU - Zheteyeva, Yenlik AU - Schrag, Stephanie J AU - Fry, Alicia M Y1 - 2012/09/15/ PY - 2012 DA - 2012 Sep 15 SP - 519 EP - 526 PB - Oxford University Press, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 176 IS - 6 SN - 0002-9262, 0002-9262 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Mortality KW - Data processing KW - Pediatrics KW - Influenza A KW - Summer KW - Children KW - Public health KW - Influenza KW - pandemics KW - Intensive care units KW - USA, Georgia, Atlanta KW - Waves KW - Outbreaks KW - Emergency medical services KW - Hospitals KW - H 12000:Epidemiology and Public Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1125237337?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Epidemiology&rft.atitle=The+Burden+and+Severity+of+Illness+Due+to+2009+Pandemic+Influenza+A+%28H1N1%29+in+a+Large+US+City+During+the+Late+Summer+and+Early+Fall+of+2009&rft.au=Doshi%2C+Saumil+S%3BStauffer%2C+Kendra+E%3BParker+Fiebelkorn%2C+Amy%3BLafond%2C+Kathryn+E%3BDavidson%2C+Heidi+A%3BApostolou%2C+Andria%3BTaylor%2C+Thomas+H%3BSmith%2C+Wendy%3BKarcz%2C+Adam+N%3BWatson%2C+JRenee%3BOpeno%2C+Kyle+P%3BBrooks%2C+Joy+G%3BZheteyeva%2C+Yenlik%3BSchrag%2C+Stephanie+J%3BFry%2C+Alicia+M&rft.aulast=Doshi&rft.aufirst=Saumil&rft.date=2012-09-15&rft.volume=176&rft.issue=6&rft.spage=519&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Epidemiology&rft.issn=00029262&rft_id=info:doi/10.1093%2Faje%2Fkws137 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-10-01 N1 - Last updated - 2013-11-04 N1 - SubjectsTermNotLitGenreText - Mortality; pandemics; Data processing; Intensive care units; Pediatrics; Influenza A; Waves; Children; Hospitals; Public health; Influenza; Summer; Outbreaks; Emergency medical services; USA, Georgia, Atlanta DO - http://dx.doi.org/10.1093/aje/kws137 ER - TY - JOUR T1 - Completeness of West Nile virus testing in patients with meningitis and encephalitis during an outbreak in Arizona, USA AN - 1367488222; 18059216 AB - Accurate data on West Nile virus (WNV) cases help guide public health education and control activities, and impact regional WNV blood product screening procedures. During an outbreak of WNV disease in Arizona, records from patients with meningitis or encephalitis were reviewed to determine the proportion tested for WNV. Of 60 patients identified with meningitis or encephalitis, 24 (40%) were tested for WNV. Only 12 (28%) of 43 patients aged <50 years were tested for WNV compared to 12 (71%) of 17 patients aged 50 years (P<0.01). Patients with clinical signs of weakness or paralysis, elevated CSF protein, admitted to an inpatient facility, or discharged to a rehabilitation facility were also more likely to have WNV testing performed. The lack of testing in younger age groups and in those with less severe disease probably resulted in substantial underestimates of WNV neuroinvasive disease burden. JF - Epidemiology and Infection AU - Weber, Ib AU - Lindsey, N P AU - BUNKO-PATTERSON, A M AU - Briggs, G AU - Wadleigh, T J AU - Sylvester, T L AU - Levy, C AU - Komatsu, K K AU - Lehman, Ja AU - Fischer, M AU - Staples, Je AD - Arboviral Diseases Branch, Centers for Disease Control and Prevention, Fort Collins, CO, USA, ggv8@cdc.gov Y1 - 2012/09// PY - 2012 DA - Sep 2012 SP - 1632 EP - 1636 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 140 IS - 9 SN - 0950-2688, 0950-2688 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Age KW - USA, Arizona KW - Outbreaks KW - West Nile virus KW - Encephalitis KW - H 12000:Epidemiology and Public Health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1367488222?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Completeness+of+West+Nile+virus+testing+in+patients+with+meningitis+and+encephalitis+during+an+outbreak+in+Arizona%2C+USA&rft.au=Weber%2C+Ib%3BLindsey%2C+N+P%3BBUNKO-PATTERSON%2C+A+M%3BBriggs%2C+G%3BWadleigh%2C+T+J%3BSylvester%2C+T+L%3BLevy%2C+C%3BKomatsu%2C+K+K%3BLehman%2C+Ja%3BFischer%2C+M%3BStaples%2C+Je&rft.aulast=Weber&rft.aufirst=Ib&rft.date=2012-09-01&rft.volume=140&rft.issue=9&rft.spage=1632&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268811002494 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-06-01 N1 - Number of references - 1 N1 - Last updated - 2014-03-10 N1 - SubjectsTermNotLitGenreText - Encephalitis; Outbreaks; West Nile virus; USA, Arizona DO - http://dx.doi.org/10.1017/S0950268811002494 ER - TY - JOUR T1 - Genotyping characteristic and drug resistance of Mycobacterium tuberculosis isolated in Weishi county of Henan province AN - 1285099643; 17544667 AB - Aim: To investigate the genotyping characteristic and drug resistance of the variable number tandem repeats (VNTR) of Mycobacterium tuberculosis clinical isolates in Weishi, Henan province with multi-locus VNTR analysis preliminarily. Methods: A total of 257 Mycobacterium tuberculosis clinical isolates selected from Weishi county randomly were cultured with Lowenstein-Jensen medium from June 2009 to June 2011. The drug susceptibility of Mycobacterium tuberculosis was determined by proportion method. The genotypes were identified by RD105 detection test and the polymorphism of 7 VNTR locus. The clustering of genotype was analyzed with BioNumerics. Results: Beijing family genotype accounted for 90.7% (233/257) by RD105 detection test. The VNTR genotypes showed obvious polymorphisms. The clustering of genotype showed that these strains could be categorized into 4 gene clusters (I, II, III and IV) and 230 genotypes. Among them, 59.1% were cluster III including 152 genotypes, which was the dominant genotype. The drug resistant result showed that there were 23 MDR-TB strains, accounting for 8.9% (23/257), any there were 63 drug resistant strains, accounting for 24.5% (63/257). The drug resistant strains distribution between Beijing family genotype and non-Beijing family genotype, as well as major population and non-major population had significant differences ( chi sub(2)=2.412 and 1.954, P>0.05). Conclusion: There are at least 4 clusters of VNTR genotype and cluster III is the predominant prevalent strain in Weishi county. The drug resistance is still not optimistic. JF - Zhengzhou Daxue Xuebao (Yixue Ban) - Journal of Zhengzhou University. Medical sciences AU - Zhao, Y AU - Ma, X AU - Li, H AU - Xu, J AU - Yan, G AU - Shi, J AD - Institution of Tuberculosis Prevention and Control, Henan Provincial Center for Disease Control and Prevention, Zhengzhou 450016, xjy3115@sohu.com Y1 - 2012/09// PY - 2012 DA - Sep 2012 SP - 691 EP - 693 VL - 47 IS - 5 SN - 1671-6825, 1671-6825 KW - Genetics Abstracts; Microbiology Abstracts B: Bacteriology KW - Clinical isolates KW - Drug resistance KW - Gene clusters KW - Gene polymorphism KW - Genotyping KW - Mycobacterium tuberculosis KW - G 07770:Bacteria KW - J 02450:Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1285099643?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Zhengzhou+Daxue+Xuebao+%28Yixue+Ban%29+-+Journal+of+Zhengzhou+University.+Medical+sciences&rft.atitle=Genotyping+characteristic+and+drug+resistance+of+Mycobacterium+tuberculosis+isolated+in+Weishi+county+of+Henan+province&rft.au=Zhao%2C+Y%3BMa%2C+X%3BLi%2C+H%3BXu%2C+J%3BYan%2C+G%3BShi%2C+J&rft.aulast=Zhao&rft.aufirst=Y&rft.date=2012-09-01&rft.volume=47&rft.issue=5&rft.spage=691&rft.isbn=&rft.btitle=&rft.title=Zhengzhou+Daxue+Xuebao+%28Yixue+Ban%29+-+Journal+of+Zhengzhou+University.+Medical+sciences&rft.issn=16716825&rft_id=info:doi/10.3969%2Fj.issn.1671-6825.2012.05.030 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-01 N1 - Last updated - 2013-03-11 N1 - SubjectsTermNotLitGenreText - Clinical isolates; Gene polymorphism; Genotyping; Drug resistance; Gene clusters; Mycobacterium tuberculosis DO - http://dx.doi.org/10.3969/j.issn.1671-6825.2012.05.030 ER - TY - JOUR T1 - Frequency-dependent Effects of Vibration on Physiological Systems: Experiments with Animals and other Human Surrogates AN - 1171880114; 17349859 AB - Occupational exposure to vibration through the use of power- and pneumatic hand-tools results in cold-induced vasospasms, finger blanching, and alterations in sensorineural function. Collectively, these symptoms are referred to as hand-arm vibration syndrome (HAVS). Currently the International Standards Organization (ISO) standard ISO 5349-1 contains a frequency-weighting curve to help workers and employers predict the risk of developing HAVS with exposure to vibration of different frequencies. However, recent epidemiological and experimental evidence suggests that this curve under-represents the risk of injuries to the hands and fingers induced by exposure to vibration at higher frequencies (>100 Hz). To improve the curve, better exposure-response data need to be collected. The goal of this review is to summarize the results of animal and computational modeling studies that have examined the frequency-dependent effects of vibration, and discuss where additional research would be beneficial to fill these research gaps. JF - Industrial Health AU - Krajnak, K AU - Riley, DA AU - Wu, J AU - McDowell, T AU - Welcome, DE AU - Xu, X S AU - Dong, R G AD - Engineering and Controls Technology Branch, National Institute for Occupational Safety and Health, USA, kkrajnak@cdc.gov Y1 - 2012/09// PY - 2012 DA - Sep 2012 SP - 343 EP - 353 VL - 50 IS - 5 SN - 0019-8366, 0019-8366 KW - Health & Safety Science Abstracts; Risk Abstracts KW - Animals KW - Dose-response effects KW - Hand-arm vibration syndrome KW - Injuries KW - International standardization KW - Occupational exposure KW - Physiology KW - Reviews KW - Vibration KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1171880114?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Industrial+Health&rft.atitle=Frequency-dependent+Effects+of+Vibration+on+Physiological+Systems%3A+Experiments+with+Animals+and+other+Human+Surrogates&rft.au=Krajnak%2C+K%3BRiley%2C+DA%3BWu%2C+J%3BMcDowell%2C+T%3BWelcome%2C+DE%3BXu%2C+X+S%3BDong%2C+R+G&rft.aulast=Krajnak&rft.aufirst=K&rft.date=2012-09-01&rft.volume=50&rft.issue=5&rft.spage=343&rft.isbn=&rft.btitle=&rft.title=Industrial+Health&rft.issn=00198366&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-11-01 N1 - Last updated - 2012-12-14 N1 - SubjectsTermNotLitGenreText - Animals; Hand-arm vibration syndrome; Injuries; Dose-response effects; Reviews; Vibration; Physiology; Occupational exposure; International standardization ER - TY - JOUR T1 - Nutritional Risk Factors for Tuberculosis Among Adults in the United States, 1971-1992 AN - 1125237202; 17317154 AB - The risk of developing tuberculosis (TB) may be related to nutritional status. To determine the impact of nutritional status on TB incidence, the authors analyzed data from the First National Health and Nutrition Examination Survey (NHANES I) Epidemiologic Follow-up Study (NHEFS). NHANES I collected information on a probability sample of the US population in 1971-1975. Adults were followed up in 1982-1992. Incident TB cases were ascertained through interviews, medical records, and death certificates. TB incidences were compared across different levels of nutritional status after controlling for potential confounding using proportional hazards regression appropriate to the complex sample design. TB incidence among adults with normal body mass index was 24.7 per 100,000 person-years (95% confidence interval (CI): 13.0, 36.3). In contrast, among persons who were underweight, overweight, and obese, estimated TB incidence rates were 260.2 (95% CI: 98.6, 421.8), 8.9 (95% CI: 2.2, 15.6), and 5.1 (95% CI: 0.0, 10.5) per 100,000 person-years, respectively. Adjusted hazard ratios were 12.43 (95% CI: 5.75, 26.95), 0.28 (95% CI: 0.13, 0.63), and 0.20 (95% CI: 0.07, 0.62), respectively, after controlling for demographic, socioeconomic, and medical characteristics. A low serum albumin level also increased the risk of TB, but low vitamin A, thiamine, riboflavin, and iron status did not. A population's nutritional profile is an important determinant of its TB incidence. JF - American Journal of Epidemiology AU - Cegielski, JPeter AU - Arab, Lenore AU - Cornoni-Huntley, Joan Y1 - 2012/09/01/ PY - 2012 DA - 2012 Sep 01 SP - 409 EP - 422 PB - Oxford University Press, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 176 IS - 5 SN - 0002-9262, 0002-9262 KW - Microbiology Abstracts B: Bacteriology; Risk Abstracts; Health & Safety Science Abstracts KW - Mycobacterium KW - Socioeconomics KW - Underweight KW - Nutrition KW - Demography KW - Body weight KW - Vitamins KW - Risk factors KW - Tuberculosis KW - Nutritional status KW - Mortality KW - Obesity KW - Data processing KW - medical records KW - Thiamine KW - Socio-economic aspects KW - USA KW - Riboflavin KW - Vitamin A KW - Albumin KW - Body mass index KW - Iron KW - J 02400:Human Diseases KW - R2 23060:Medical and environmental health KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1125237202?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Epidemiology&rft.atitle=Nutritional+Risk+Factors+for+Tuberculosis+Among+Adults+in+the+United+States%2C+1971-1992&rft.au=Cegielski%2C+JPeter%3BArab%2C+Lenore%3BCornoni-Huntley%2C+Joan&rft.aulast=Cegielski&rft.aufirst=JPeter&rft.date=2012-09-01&rft.volume=176&rft.issue=5&rft.spage=409&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Epidemiology&rft.issn=00029262&rft_id=info:doi/10.1093%2Faje%2Fkws007 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-10-01 N1 - Last updated - 2013-11-04 N1 - SubjectsTermNotLitGenreText - Nutritional status; Obesity; Data processing; medical records; Thiamine; Underweight; Nutrition; Demography; Socio-economic aspects; Body weight; Riboflavin; Vitamin A; Risk factors; Albumin; Tuberculosis; Body mass index; Iron; Mortality; Vitamins; Socioeconomics; Mycobacterium; USA DO - http://dx.doi.org/10.1093/aje/kws007 ER - TY - JOUR T1 - Epidemiology of Ehrlichiosis and Anaplasmosis among American Indians in the United States, 2000-2007 AN - 1113221654; 17254215 AB - Ehrlichiosis and anaplasmosis infections among American Indians (AIs) have never been specifically examined, despite high rates of other tick-borne rickettsial diseases among AIs. The epidemiology of ehrlichiosis and anaplasmosis among AIs was analyzed using the National Electronic Telecommunications System for Surveillance (NETSS), Case Report Forms (CRFs), and Indian Health Service (IHS) inpatient and outpatient visits. The 2000-2007 average annual ehrlichiosis and anaplasmosis incidence among AIs reported to NETSS was almost 4-fold lower (4.0/1,000,000) than that using IHS data (14.9). American Indian cases reported from CRFs had a higher proportion of hospitalization (44%) compared with IHS (10%). American Indian incidence of ehrlichiosis and anaplasmosis was higher and showed a different age and geographical distribution than other races. These results highlight the need to improve collaboration between the ehrlichiosis and anaplasmosis surveillance systems for AIs so as to develop interventions that target the unique epidemiology and mitigate the burden of disease among this high-risk population. JF - American Journal of Tropical Medicine and Hygiene AU - Folkema, A M AU - Holman, R C AU - Dahlgren, F S AU - Cheek, JE AU - McQuiston, J H AD - Division of Vector-Borne Diseases (DVBD), National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), Centers for Disease Control and Prevention (CDC), 1600 Clifton Rd. NE, Mailstop A-30, Atlanta, GA 30329, USA, JMcquiston@cdc.gov Y1 - 2012/09// PY - 2012 DA - September 2012 SP - 529 EP - 537 VL - 87 IS - 3 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; Risk Abstracts KW - Age KW - Geographical distribution KW - Age composition KW - Data processing KW - Intervention KW - Ehrlichiosis KW - Infection KW - USA KW - telecommunications KW - Anaplasmosis KW - Epidemiology KW - Case reports KW - Risk groups KW - Ethnic groups KW - Races KW - K 03400:Human Diseases KW - J 02400:Human Diseases KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1113221654?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Epidemiology+of+Ehrlichiosis+and+Anaplasmosis+among+American+Indians+in+the+United+States%2C+2000-2007&rft.au=Folkema%2C+A+M%3BHolman%2C+R+C%3BDahlgren%2C+F+S%3BCheek%2C+JE%3BMcQuiston%2C+J+H&rft.aulast=Folkema&rft.aufirst=A&rft.date=2012-09-01&rft.volume=87&rft.issue=3&rft.spage=529&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.2012.12-0060 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-10-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Age composition; Geographical distribution; Data processing; Anaplasmosis; Case reports; Epidemiology; Risk groups; Ehrlichiosis; Infection; Races; Age; telecommunications; Intervention; Ethnic groups; USA DO - http://dx.doi.org/10.4269/ajtmh.2012.12-0060 ER - TY - JOUR T1 - Survival and persistence of nonspore-forming biothreat agents in water AN - 1038600482; 17105629 AB - Aims: To determine whether nonspore-forming biothreat agents can survive and persist in potable water that does not contain a disinfectant. Methods and Results: Autoclaved, de-chlorinated Atlanta municipal water was inoculated with eight isolates of bacterial biothreat agents (106CFUml-1). The inoculated water samples were incubated at 5, 8 (Francisella tularensis only) or 25 degree C and assayed for viability by culture and by the presence of metabolic activity as measured by esterase activity (ScanRDI, AES Chemunex). Viability as determined by culture varied from 1 to 30days, depending upon the organism and the temperature of the water. All organisms were determined viable as measured by esterase activity for the entire 30days, regardless of the incubation temperature. Conclusion:Francisella tularensis was culturable for at least 21days if held at 8 degree C. The remaining nonspore-forming bacterial biothreat agents were found to be metabolically active for at least 30days in water held at 5 or 25 degree C. Significance and Impact of the Study: The data can assist public health officials to determine the safety of drinking water after contamination with a biothreat agent. JF - Letters in Applied Microbiology AU - Gilbert, SE AU - Rose, L J AD - Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA Y1 - 2012/09// PY - 2012 DA - Sep 2012 SP - 189 EP - 194 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 55 IS - 3 SN - 0266-8254, 0266-8254 KW - Microbiology Abstracts A: Industrial & Applied Microbiology KW - Temperature effects KW - Disinfectants KW - Data processing KW - Contamination KW - esterase KW - Survival KW - Francisella tularensis KW - Water temperature KW - Drinking water KW - Public health KW - A 01450:Environmental Pollution & Waste Treatment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1038600482?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Letters+in+Applied+Microbiology&rft.atitle=Survival+and+persistence+of+nonspore-forming+biothreat+agents+in+water&rft.au=Gilbert%2C+SE%3BRose%2C+L+J&rft.aulast=Gilbert&rft.aufirst=SE&rft.date=2012-09-01&rft.volume=55&rft.issue=3&rft.spage=189&rft.isbn=&rft.btitle=&rft.title=Letters+in+Applied+Microbiology&rft.issn=02668254&rft_id=info:doi/10.1111%2Fj.1472-765X.2012.03277.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-09-01 N1 - Document feature - figure 2 N1 - Last updated - 2013-07-26 N1 - SubjectsTermNotLitGenreText - Temperature effects; Disinfectants; Data processing; Contamination; esterase; Survival; Water temperature; Drinking water; Public health; Francisella tularensis DO - http://dx.doi.org/10.1111/j.1472-765X.2012.03277.x ER - TY - JOUR T1 - Ultrafiltration improves ELISA and Endopep MS analysis of botulinum neurotoxin type A in drinking water. AN - 1027836635; 22677607 AB - The objective of this study was to adapt and evaluate two in vitro botulinum neurotoxin (BoNT) detection methods, including the Botulinum Toxin ELISA and the Endopep MS (a mass spectrometric-based endopeptidase method), for use with drinking water samples. The method detection limits (MDL) of the ELISA and Endopep MS were 260 pg/mL and 21 pg/mL of BoNT/A complex toxin, respectively. Since toxin could be present in water samples at highly dilute concentrations, large volume (100-L) samples of municipal tap water from five US municipalities having distinct water compositions were dechlorinated, spiked with 5 μg BoNT/A, and subjected to tangential-flow ultrafiltration (UF) using hollow fiber dialyzers. The recovery efficiency of BoNT/A using UF and quantified by ELISA ranged from 11% to 36% while efficiencies quantified by MS ranged from 26% to 55%. BoNT/A was shown to be stable in dechlorinated municipal tap water stored at 4°C for up to four weeks. In addition, toxin present in UF-concentrated water samples was also shown to be stable at 4°C for up to four weeks, allowing holding of samples prior to analysis. Finally, UF was used to concentrate a level of toxin (7 pg/mL) which is below the MDL for direct analysis by both ELISA and Endopep MS. Following UF, toxin was detectable in these samples using both in vitro analysis methods. These data demonstrate that UF-concentration of toxin from large volume water samples followed by use of existing analytical methods for detection of BoNT/A can be used in support of a monitoring program for contaminants in drinking water. Published by Elsevier B.V. JF - Journal of microbiological methods AU - Raphael, Brian H AU - Lautenschlager, Matthew AU - Kahler, Amy AU - Pai, Suresh AU - Parks, Bryan A AU - Kalb, Suzanne R AU - Maslanka, Susan E AU - Shah, Sanjiv AU - Magnuson, Matthew AU - Hill, Vincent R AD - Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. BRaphael@cdc.gov Y1 - 2012/09// PY - 2012 DA - September 2012 SP - 267 EP - 272 VL - 90 IS - 3 KW - Drinking Water KW - 0 KW - Botulinum Toxins, Type A KW - EC 3.4.24.69 KW - Index Medicus KW - Ultrafiltration KW - Mass Spectrometry KW - Animals KW - Mice, Inbred ICR KW - Enzyme-Linked Immunosorbent Assay -- standards KW - Enzyme Stability KW - Reference Standards KW - Linear Models KW - Calibration KW - Mice KW - Limit of Detection KW - Water Microbiology KW - Drinking Water -- analysis KW - Enzyme Assays KW - Botulinum Toxins, Type A -- analysis KW - Botulinum Toxins, Type A -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1027836635?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+microbiological+methods&rft.atitle=Ultrafiltration+improves+ELISA+and+Endopep+MS+analysis+of+botulinum+neurotoxin+type+A+in+drinking+water.&rft.au=Raphael%2C+Brian+H%3BLautenschlager%2C+Matthew%3BKahler%2C+Amy%3BPai%2C+Suresh%3BParks%2C+Bryan+A%3BKalb%2C+Suzanne+R%3BMaslanka%2C+Susan+E%3BShah%2C+Sanjiv%3BMagnuson%2C+Matthew%3BHill%2C+Vincent+R&rft.aulast=Raphael&rft.aufirst=Brian&rft.date=2012-09-01&rft.volume=90&rft.issue=3&rft.spage=267&rft.isbn=&rft.btitle=&rft.title=Journal+of+microbiological+methods&rft.issn=1872-8359&rft_id=info:doi/10.1016%2Fj.mimet.2012.05.020 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-11-26 N1 - Date created - 2012-07-24 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.mimet.2012.05.020 ER - TY - JOUR T1 - Outbreak of Human Trichinellosis in Northern California Caused by Trichinella murrelli AN - 1753466218; 17254179 AB - In October of 2008, an outbreak of trichinellosis occurred in northern California that sickened 30 of 38 attendees of an event at which meat from a black bear was served. Morphologic and molecular testing of muscle from the leftover portion of bear meat revealed that the bear was infected with Trichinella murrelli, a sylvatic species of Trichinella found in temperate North America. Clinical records revealed a high attack rate for this outbreak: 78% for persons consuming any bear meat and 100% for persons consuming raw or undercooked bear meat. To our knowledge, this report is the first published report of a human trichinellosis outbreak in the United States attributed to T. murrelli, and it is the second such outbreak reported worldwide. JF - American Journal of Tropical Medicine and Hygiene AU - Hall, R L AU - Lindsay, A AU - Hammond, C AU - Montgomery, S P AU - Wilkins, P P AU - da Silva, AJ AU - McAuliffe, I AU - de Almeida, M AU - Bishop, H AU - Mathison, B AU - Sun, B AU - Largusa, R AU - Jones, J L AD - 1600 Clifton Road, NE, Mailstop A-06, Atlanta, CA 30333, USA, bqu5@cdc.gov Y1 - 2012/08// PY - 2012 DA - August 2012 SP - 297 EP - 302 VL - 87 IS - 2 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology KW - Meat KW - Muscles KW - trichinellosis KW - Trichinella KW - K 03300:Methods KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1753466218?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Outbreak+of+Human+Trichinellosis+in+Northern+California+Caused+by+Trichinella+murrelli&rft.au=Hall%2C+R+L%3BLindsay%2C+A%3BHammond%2C+C%3BMontgomery%2C+S+P%3BWilkins%2C+P+P%3Bda+Silva%2C+AJ%3BMcAuliffe%2C+I%3Bde+Almeida%2C+M%3BBishop%2C+H%3BMathison%2C+B%3BSun%2C+B%3BLargusa%2C+R%3BJones%2C+J+L&rft.aulast=Hall&rft.aufirst=R&rft.date=2012-08-01&rft.volume=87&rft.issue=2&rft.spage=297&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/10.4269%2Fajtmh.2012.12-0075 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-01-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - Meat; Muscles; trichinellosis; Trichinella DO - http://dx.doi.org/10.4269/ajtmh.2012.12-0075 ER - TY - JOUR T1 - Trends in National Surveillance Data for Bat Rabies in the United States: 2001-2009 AN - 1315613906; 17718355 AB - Rabies remains an important public health concern in the United States, with most human cases associated with bat rabies virus variants. Cases of rabies virus (RV) infection in bats are widely distributed across the continental United States and elsewhere in the Americas. In this retrospective study, data on bats submitted to state laboratories for RV diagnosis between 2001 and 2009 were analyzed to investigate epidemiological trends in the United States. Season, region, and roosting habits were the primary risk factors of interest. During the study interval, more than 205,439 bats were submitted for RV diagnosis, and 6.7% of these bats were rabid. Increased odds of a submitted bat being rabid were associated with species that exhibit inconspicuous roosting habits, bats originating in the Southwest, and bats submitted for diagnosis during the fall. Periodic analysis of zoonotic disease surveillance is recommended to detect changes in trends regarding geographic distribution, seasonal fluctuations, and host associations; this is particularly necessary, as existing trends may be influenced by climate change or other emerging factors. JF - Vector Borne and Zoonotic Diseases AU - Patyk, K AU - Turmelle, A AU - Blanton, J D AU - Rupprecht, CE AD - National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road N.E., Mailstop G33, Atlanta, GA 30333, USA, asi5@cdc.gov Y1 - 2012/08// PY - 2012 DA - August 2012 SP - 666 EP - 673 VL - 12 IS - 8 SN - 1530-3667, 1530-3667 KW - Risk Abstracts; Health & Safety Science Abstracts; Sustainability Science Abstracts; Virology & AIDS Abstracts KW - Geographical distribution KW - Data processing KW - Climate change KW - Climatic changes KW - Vectors KW - Infection KW - Public health KW - USA KW - Sulfur dioxide KW - Rabies KW - Risk factors KW - Rabies virus KW - Seasonal variations KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - M3 1010:Issues in Sustainable Development KW - R2 23060:Medical and environmental health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1315613906?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vector+Borne+and+Zoonotic+Diseases&rft.atitle=Trends+in+National+Surveillance+Data+for+Bat+Rabies+in+the+United+States%3A+2001-2009&rft.au=Patyk%2C+K%3BTurmelle%2C+A%3BBlanton%2C+J+D%3BRupprecht%2C+CE&rft.aulast=Patyk&rft.aufirst=K&rft.date=2012-08-01&rft.volume=12&rft.issue=8&rft.spage=666&rft.isbn=&rft.btitle=&rft.title=Vector+Borne+and+Zoonotic+Diseases&rft.issn=15303667&rft_id=info:doi/10.1089%2Fvbz.2011.0839 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-03-01 N1 - Last updated - 2016-07-07 N1 - SubjectsTermNotLitGenreText - Geographical distribution; Data processing; Risk factors; Rabies; Climatic changes; Vectors; Infection; Public health; Sulfur dioxide; Climate change; Seasonal variations; Rabies virus; USA DO - http://dx.doi.org/10.1089/vbz.2011.0839 ER - TY - JOUR T1 - Systematic review of behavior change research on point-of-use water treatment interventions in countries categorized as low- to medium-development on the human development index AN - 1171881358; 16867401 AB - Point-of-use water treatment (i.e., water purification at the point of consumption) has proven effective in preventing diarrhea in developing countries. However, widespread adoption has not occurred, suggesting that implementation strategies have not motivated sustained behavior change. We conducted a systematic literature review of published behavioral research on factors influencing adoption of point-of-use water treatment in countries categorized as low- to medium-development on the United Nations Development Programme Human Development Index. We used 22 key words to search peer-reviewed literature from 1950 to 2010 from OVID Medline, CINAHL, and PsycINFO. Twenty-six (1.7%) of 1551 papers met our four inclusion criteria: 1) implemented a point-of-use water treatment intervention, 2) applied a behavioral intervention, 3) evaluated behavior change as the outcome, and 4) occurred in a low- or medium-development country. We reviewed these 26 publications for detailed descriptions of the water treatment intervention, theoretical rationales for the behavioral intervention, and descriptions of the evaluation. In 5 (19%) papers, details of the behavioral intervention were fully specified. Seven (27%) papers reported using a behavioral theory in the design of the intervention and evaluation of its impact. Ten (38%) studies used a comparison or control group; 5 provided detailed descriptions. Seven (27%) papers reported high sustained use of point-of-use water treatment with rates >50% at the last recorded follow-up. Despite documented health benefits of point-of-use water treatment interventions in reducing diarrheal diseases, we found limited peer-reviewed behavioral research on the topic. In addition, we found the existing literature often lacked detailed descriptions of the intervention for replication, seldom described the theoretical and empirical rationale for the implementation and evaluation of the intervention, and often had limitations in the evaluation methodology. The scarcity of papers on behavior change with respect to point-of-use water treatment technologies suggests that this field is underdeveloped. JF - Social Science and Medicine AU - Parker Fiebelkorn, Amy AU - Person, Bobbie AU - Quick, Robert E AU - Vindigni, Stephen M AU - Jhung, Michael AU - Bowen, Anna AU - Riley, Patricia L AD - Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention (CDC), 1600 Clifton Road, MS A-34, Atlanta, GA 30333, USA, Afiebelkorn@cdc.gov Y1 - 2012/08// PY - 2012 DA - Aug 2012 SP - 622 EP - 633 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 75 IS - 4 SN - 0277-9536, 0277-9536 KW - Pollution Abstracts; Environment Abstracts KW - Behavior KW - Developing countries KW - Intervention KW - Literature reviews KW - Technology KW - United Nations KW - Water purification KW - Water treatment KW - P 2000:FRESHWATER POLLUTION KW - ENA 16:Renewable Resources-Water UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1171881358?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Social+Science+and+Medicine&rft.atitle=Systematic+review+of+behavior+change+research+on+point-of-use+water+treatment+interventions+in+countries+categorized+as+low-+to+medium-development+on+the+human+development+index&rft.au=Parker+Fiebelkorn%2C+Amy%3BPerson%2C+Bobbie%3BQuick%2C+Robert+E%3BVindigni%2C+Stephen+M%3BJhung%2C+Michael%3BBowen%2C+Anna%3BRiley%2C+Patricia+L&rft.aulast=Parker+Fiebelkorn&rft.aufirst=Amy&rft.date=2012-08-01&rft.volume=75&rft.issue=4&rft.spage=622&rft.isbn=&rft.btitle=&rft.title=Social+Science+and+Medicine&rft.issn=02779536&rft_id=info:doi/10.1016%2Fj.socscimed.2012.02.011 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-11-01 N1 - Last updated - 2012-12-28 N1 - SubjectsTermNotLitGenreText - Behavior; Literature reviews; Water treatment; Intervention; United Nations; Developing countries; Water purification; Technology DO - http://dx.doi.org/10.1016/j.socscimed.2012.02.011 ER - TY - JOUR T1 - Characterization of Frequency-Dependent Responses of the Vascular System to Repetitive Vibration AN - 1069194397; 17126147 AB - Objective: Occupational exposure to hand-transmitted vibration can result in damage to nerves and sensory loss. The goal of this study was to assess the frequency-dependent effects of repeated bouts of vibration on sensory nerve function and associated changes in nerves. Methods: The tails of rats were exposed to vibration at 62.5, 125, or 250 Hz (constant acceleration of 49 m/s super(2)) for 10 days. The effects on sensory nerve function, nerve morphology, and transcript expression in ventral tail nerves were measured. Results: Vibration at all frequencies had effects on nerve function and physiology. However, the effects tended to be more prominent with exposure at 250 Hz. Conclusion: Exposure to vibration has detrimental effects on sensory nerve function and physiology. However, many of these changes are more prominent at 250-Hz exposure than at lower frequencies. JF - Journal of Occupational and Environmental Medicine AU - Krajnak, K AU - Miller, G R AU - Waugh, S AU - Johnson, C AU - Kashon, M L AD - NIOSH, 1095 Willowdale Rd, MS2027, Morgantown, WV 26505, USA, ksk1@cdc.gov Y1 - 2012/08// PY - 2012 DA - Aug 2012 SP - 1010 EP - 1016 VL - 54 IS - 8 SN - 1076-2752, 1076-2752 KW - Health & Safety Science Abstracts KW - Morphology KW - Occupational exposure KW - Physiology KW - Rats KW - Vibration KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1069194397?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Characterization+of+Frequency-Dependent+Responses+of+the+Vascular+System+to+Repetitive+Vibration&rft.au=Krajnak%2C+K%3BMiller%2C+G+R%3BWaugh%2C+S%3BJohnson%2C+C%3BKashon%2C+M+L&rft.aulast=Krajnak&rft.aufirst=K&rft.date=2012-08-01&rft.volume=54&rft.issue=8&rft.spage=1010&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e318255ba74 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-09-01 N1 - Last updated - 2012-10-08 N1 - SubjectsTermNotLitGenreText - Rats; Vibration; Morphology; Physiology; Occupational exposure DO - http://dx.doi.org/10.1097/JOM.0b013e318255ba74 ER - TY - JOUR T1 - Estimated prevalence of dengue viremia in Puerto Rican blood donations, 1995 through 2010 AN - 1038606956; 17090339 AB - BACKGROUND: Dengue virus (DENV) nucleic acid amplification testing of blood donations during epidemics in endemic locations, including Puerto Rico, has suggested possible sizable transfusion transmission risk. Estimates of the long-term prevalence of DENV viremic donations will help evaluate the potential magnitude of this risk in Puerto Rico. STUDY DESIGN AND METHODS: Estimates of the prevalence of DENV viremia in the Puerto Rican population at large from 1995 through 2010 were derived from dengue case reports and their onset dates obtained from islandwide surveillance, estimates of case underreporting, and extant data on the duration of DENV viremia and the unapparent-to-apparent dengue infection ratio. Under the assumptions that viremia prevalence in blood donors was similar to that of the population at large and that symptomatic persons do not donate, statistical resampling methods were used to estimate the prevalence of dengue viremia in blood donations. RESULTS: Over the 16-year period, the maximum and mean daily prevalences of dengue viremia (per 10,000) in blood donations in Puerto Rico were estimated at 45.0 (95% confidence interval [CI], 36.5-55.4) and 7.0 (95% CI, 3.9-10.1), respectively. Prevalence varied considerably by season and year. CONCLUSION: These data suggest a substantial prevalence of DENV viremia in Puerto Rican blood donations, particularly during outbreaks. JF - Transfusion AU - Petersen, Lyle R AU - Tomashek, Kay M AU - Biggerstaff, Brad J AD - From the Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado. Y1 - 2012/08// PY - 2012 DA - August 2012 SP - 1647 EP - 1651 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 52 IS - 8 SN - 0041-1132, 0041-1132 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Virology & AIDS Abstracts; Risk Abstracts KW - Dengue virus KW - Blood donors KW - Data processing KW - Statistics KW - Epidemics KW - Surveillance and enforcement KW - transfusion KW - Infection KW - Transfusion KW - Disease transmission KW - Blood KW - Endemic species KW - nucleic acids KW - Case reports KW - ASW, Caribbean Sea, Greater Antilles, Puerto Rico KW - Dengue KW - Outbreaks KW - Viremia KW - Nucleic acids KW - Q1 08604:Stock assessment and management KW - R2 23060:Medical and environmental health KW - Q5 08524:Public health, medicines, dangerous organisms KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1038606956?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Transfusion&rft.atitle=Estimated+prevalence+of+dengue+viremia+in+Puerto+Rican+blood+donations%2C+1995+through+2010&rft.au=Petersen%2C+Lyle+R%3BTomashek%2C+Kay+M%3BBiggerstaff%2C+Brad+J&rft.aulast=Petersen&rft.aufirst=Lyle&rft.date=2012-08-01&rft.volume=52&rft.issue=8&rft.spage=1647&rft.isbn=&rft.btitle=&rft.title=Transfusion&rft.issn=00411132&rft_id=info:doi/10.1111%2Fj.1537-2995.2011.03529.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-09-01 N1 - Document feature - figure 1 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Blood; Endemic species; Epidemics; Surveillance and enforcement; Nucleic acids; Blood donors; nucleic acids; Statistics; Data processing; Case reports; Dengue; Viremia; Transfusion; Infection; Disease transmission; transfusion; Outbreaks; Dengue virus; ASW, Caribbean Sea, Greater Antilles, Puerto Rico DO - http://dx.doi.org/10.1111/j.1537-2995.2011.03529.x ER - TY - JOUR T1 - Lessons learned during tuberculosis screening in public medical clinics in Francistown, Botswana AN - 1034820338; 16979570 AB - In Botswana, where one quarter of the adult population is infected with the human immunodeficiency virus and the annual tuberculosis (TB) incidence is among the highest globally, intensified TB case finding is needed in health care facilities to detect and treat TB cases early and prevent transmission. During August-December 2009, TB screening was implemented among adults at patient intake in five clinics in Francistown. Among 11 779 TB screenings at intake, 926 were positive. Nineteen patients were diagnosed with TB. Routine TB screening at intake was operationally feasible, but had low yield. Innovative case-finding strategies are needed in Botswana. JF - International Journal of Tuberculosis and Lung Disease AU - Bloss, E AU - Makombe, R AU - Kip, E AU - Smit, M AU - Chirenda, J AU - Gammino, V M AU - Creek, T AU - Oeltmann, JE AD - Division of Tuberculosis Elimination, International Research and Programs Branch, CDC, 1600 Clifton Road, MS E-10, Atlanta, GA 30333, USA, dpu2@cdc.gov Y1 - 2012/08// PY - 2012 DA - Aug 2012 SP - 1030 EP - 1032 PB - International Union Against Tuberculosis and Lung Disease VL - 16 IS - 8 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts KW - Health care KW - Human immunodeficiency virus KW - Mycobacterium KW - Lung KW - Lung diseases KW - Botswana KW - Tuberculosis KW - Innovations KW - Disease transmission KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1034820338?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Lessons+learned+during+tuberculosis+screening+in+public+medical+clinics+in+Francistown%2C+Botswana&rft.au=Bloss%2C+E%3BMakombe%2C+R%3BKip%2C+E%3BSmit%2C+M%3BChirenda%2C+J%3BGammino%2C+V+M%3BCreek%2C+T%3BOeltmann%2C+JE&rft.aulast=Bloss&rft.aufirst=E&rft.date=2012-08-01&rft.volume=16&rft.issue=8&rft.spage=1030&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-08-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Lung diseases; Tuberculosis; Disease transmission; Health care; Lung; Innovations; Mycobacterium; Human immunodeficiency virus; Botswana ER - TY - JOUR T1 - Recent Advance on the Detection of Staphylococcus Aureus Enterotoxins AN - 1125225869; 17226795 AB - Staphylococcus aureus is a major human and zoonotic pathogen widely spreading in the nature. It can produce staphylococcal enterotoxins (SE) and induce food poisoning. Detection of SE is listed in food safety inspection regulations with the improving of people's awareness about food safety. It is necessary to establish a rapid and sensitive method for detection of SE to insure food safety. JF - Progress In Modern Biomedicine AU - Yun, S AU - Suo, X-M AU - Xu, Z-T AU - Yang, J-P AU - Li, Y-X AD - Bayannaoer Center For Disease Control And Prevention in Inner, Mongolia, Linhe, 015000, yunsheng8585@163.com Y1 - 2012/07// PY - 2012 DA - Jul 2012 SP - 3756 EP - 3758 VL - 12 IS - 19 SN - 1673-6273, 1673-6273 KW - Microbiology Abstracts B: Bacteriology KW - Indexing in process UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1125225869?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Progress+In+Modern+Biomedicine&rft.atitle=Recent+Advance+on+the+Detection+of+Staphylococcus+Aureus+Enterotoxins&rft.au=Yun%2C+S%3BSuo%2C+X-M%3BXu%2C+Z-T%3BYang%2C+J-P%3BLi%2C+Y-X&rft.aulast=Yun&rft.aufirst=S&rft.date=2012-07-01&rft.volume=12&rft.issue=19&rft.spage=3756&rft.isbn=&rft.btitle=&rft.title=Progress+In+Modern+Biomedicine&rft.issn=16736273&rft_id=info:doi/ LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-10-01 N1 - Last updated - 2012-11-02 ER - TY - JOUR T1 - Survey of isoniazid preventive therapy in South Africa, 2011 AN - 1032895155; 16910243 AB - SETTING: Public health facilities in South Africa. OBJECTIVE: To assess the implementation of isoniazid preventive treatment (IPT) in South Africa in 2011. DESIGN: Cross-sectional study of 50 randomly selected facilities in South Africa. Trained interviewers administered a standardised questionnaire at each facility on aspects of IPT policy, implementation and recording and reporting. We calculated and compared descriptive statistics by province and facility type. RESULTS: Of the 49 participating sites, 35 provided IPT (71%). IPT was not available in any Western Cape facility (0%), and it was available at a few Mpumalanga (40%) and Limpopo (20%) sites. In February 2011, 46% of eligible human immunodeficiency virus (HIV) infected patients at IPT-providing sites had been initiated on IPT. Implementation by facility type was 27% among community health centres. Of all facilities with integrated tuberculosis (TB) and HIV committees (TB-HIV), 85% offered IPT compared to 59% of those without TB-HTV committees (P = 0.12). Availability of the 2010 South African National IPT guidelines was statistically significantly associated with sites providing IPT (84% vs. 29%, P = 0.006). CONCLUSION: IPT implementation in South Africa began in February 2011. The availability of IPT guidelines was strongly associated with IPT uptake. More operational studies are needed to improve IPT implementation among HIV-infected patients in South Africa. JF - International Journal of Tuberculosis and Lung Disease AU - Chehab, J C AU - Vilakazi-Nhlapo, K AU - Vranken, P AU - Peters, A AU - Klausner, J D AD - CDC South Africa, 2nd Floor, CBE Building, Brooklyn, P O Box 9536 0001, Pretoria, South Africa, ChehabJ@sa.cdc.gov Y1 - 2012/07// PY - 2012 DA - Jul 2012 SP - 903 EP - 907 PB - International Union Against Tuberculosis and Lung Disease VL - 16 IS - 7 SN - 1027-3719, 1027-3719 KW - Health & Safety Science Abstracts KW - Mycobacterium KW - Human immunodeficiency virus KW - Lung KW - South Africa, Western Cape KW - Committees KW - Guidelines KW - Tuberculosis KW - South Africa, Mpumalanga KW - Public health KW - H 6000:Natural Disasters/Civil Defense/Emergency Management UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1032895155?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Survey+of+isoniazid+preventive+therapy+in+South+Africa%2C+2011&rft.au=Chehab%2C+J+C%3BVilakazi-Nhlapo%2C+K%3BVranken%2C+P%3BPeters%2C+A%3BKlausner%2C+J+D&rft.aulast=Chehab&rft.aufirst=J&rft.date=2012-07-01&rft.volume=16&rft.issue=7&rft.spage=903&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-08-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Lung; Human immunodeficiency virus; Committees; Guidelines; Tuberculosis; Public health; Mycobacterium; South Africa, Western Cape; South Africa, Mpumalanga ER - TY - JOUR T1 - UC781 Microbicide Gel Retains Anti-HIV Activity in Cervicovaginal Lavage Fluids Collected following Twice-Daily Vaginal Application AN - 1028031907; 16873929 AB - The potent nonnucleoside reverse transcriptase inhibitor UC781 has been safety tested as a vaginal microbicide gel formulation for prevention of HIV-1 sexual transmission. To investigate whether UC781 retained anti-infective activity following exposure to the female genital tract, we conducted an ex vivo analysis of the UC781 levels and antiviral activity in cervicovaginal lavage (CVL) fluids from 25 Thai women enrolled in a 14-day safety trial of twice-daily vaginal application of two concentrations of the UC781 microbicide gel. CVL samples were collected from women in the 0.1% (n = 5), 0.25% (n = 15), and placebo (n = 5) gel arms following the first application of gel (T15 min) and 8 to 24 h after the final application (T8-24 h) and separated into cell-free (CVL-s) and pelletable (CVL-p) fractions. As UC781 is highly hydrophobic, there were significantly higher levels of UC781 in the CVL-p samples than in the CVL-s samples for the UC781 gel arms. In T8-24 h CVL-p samples, 2/5 and 13/15 samples collected from the 0.1% and 0.25% UC781 gel arms, respectively, efficiently blocked infection with greater than or equal to 4 log10 50% tissue culture infective dose (TCID50) of a CCR5-tropic CRF01_AE HIV-1 virus stock. Independent of the arm, the 11 CVL-p samples with UC781 levels of greater than or equal to 5 mu g/CVL sample reduced infectious HIV by greater than or equal to 4 log10 TCID50. Our results suggest that the levels and anti-infective activities of UC781 gel formulations are likely to be associated with a cellular or pelletable component in CVL samples. Therefore, cellular and pelletable fractions should be assayed for drug levels and anti-infective activity in preclinical studies of candidate microbicides. JF - Antimicrobial Agents & Chemotherapy AU - Haaland, Richard E AU - Evans-Strickfaden, Tammy AU - Holder, Angela AU - Pau, Chou-Pong AU - McNicholl, Janet M AU - Chaikummao, Supraporn AU - Chonwattana, Wannee AU - Hart, Clyde E AD - Laboratory Branch, Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, RichardE.Haaland,hyw9{at}cdc.gov. Y1 - 2012/07// PY - 2012 DA - Jul 2012 SP - 3592 EP - 3596 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 56 IS - 7 SN - 0066-4804, 0066-4804 KW - Virology & AIDS Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Antiviral activity KW - Antiviral agents KW - Corticotropin-releasing hormone KW - Disease transmission KW - Drug development KW - Genital tract KW - Hydrophobicity KW - Infection KW - Tissue culture KW - Vagina KW - microbicides KW - non-nucleoside reverse transcriptase inhibitors KW - Human immunodeficiency virus KW - Human immunodeficiency virus 1 KW - A 01340:Antibiotics & Antimicrobials KW - V 22360:AIDS and HIV UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1028031907?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=UC781+Microbicide+Gel+Retains+Anti-HIV+Activity+in+Cervicovaginal+Lavage+Fluids+Collected+following+Twice-Daily+Vaginal+Application&rft.au=Haaland%2C+Richard+E%3BEvans-Strickfaden%2C+Tammy%3BHolder%2C+Angela%3BPau%2C+Chou-Pong%3BMcNicholl%2C+Janet+M%3BChaikummao%2C+Supraporn%3BChonwattana%2C+Wannee%3BHart%2C+Clyde+E&rft.aulast=Haaland&rft.aufirst=Richard&rft.date=2012-07-01&rft.volume=56&rft.issue=7&rft.spage=3592&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.00452-12 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-07-01 N1 - Number of references - 31 N1 - Last updated - 2012-09-10 N1 - SubjectsTermNotLitGenreText - non-nucleoside reverse transcriptase inhibitors; Antiviral agents; Vagina; Genital tract; Hydrophobicity; Drug development; Tissue culture; Infection; Antiviral activity; Corticotropin-releasing hormone; Disease transmission; microbicides; Human immunodeficiency virus; Human immunodeficiency virus 1 DO - http://dx.doi.org/10.1128/AAC.00452-12 ER - TY - JOUR T1 - Investigation of the first laboratory-acquired human cowpox virus infection in the United States. AN - 1017621943; 22539811 AB - Cowpox virus is an Orthopoxvirus that can cause infections in humans and a variety of animals. Infections occur in Eurasia; infections in humans and animals have not been reported in the United States. This report describes the occurrence of the first known human case of laboratory-acquired cowpox virus infection in the United States and the ensuing investigation. The patient and laboratory personnel were interviewed, and laboratory activities were reviewed. Real-time polymerase chain reaction (PCR) and serologic assays were used to test the patient's specimens. PCR assays were used to test specimens obtained during the investigation. A specimen from the patient's lesion tested positive for cowpox virus DNA. Genome sequencing revealed a recombinant region consistent with a strain of cowpox virus stored in the research laboratory's freezer. Cowpox virus contamination was detected in 6 additional laboratory stocks of viruses. Orthopoxvirus DNA was present in 3 of 20 environmental swabs taken from laboratory surfaces. The handling of contaminated reagents or contact with contaminated surfaces was likely the mode of transmission. Delays in recognition and diagnosis of this infection in a laboratory researcher underscore the importance of a thorough patient history-including occupational information-and laboratory testing in facilitating a prompt investigation and application of control and remediation measures. JF - The Journal of infectious diseases AU - McCollum, Andrea M AU - Austin, Connie AU - Nawrocki, John AU - Howland, Julia AU - Pryde, Julie AU - Vaid, Awais AU - Holmes, David AU - Weil, M Ryan AU - Li, Yu AU - Wilkins, Kimberly AU - Zhao, Hui AU - Smith, Scott K AU - Karem, Kevin AU - Reynolds, Mary G AU - Damon, Inger K AD - Poxvirus Team, Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. amccollum@cdc.gov Y1 - 2012/07/01/ PY - 2012 DA - 2012 Jul 01 SP - 63 EP - 68 VL - 206 IS - 1 KW - DNA, Viral KW - 0 KW - Abridged Index Medicus KW - Index Medicus KW - Humans KW - DNA Contamination KW - United States -- epidemiology KW - Cowpox virus -- genetics KW - Laboratory Infection -- epidemiology KW - Laboratory Personnel KW - Infectious Disease Transmission, Patient-to-Professional KW - Cowpox -- virology KW - Laboratory Infection -- virology KW - DNA, Viral -- isolation & purification KW - Cowpox virus -- isolation & purification KW - Cowpox -- transmission KW - DNA, Viral -- genetics KW - Laboratory Infection -- transmission KW - Cowpox -- epidemiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1017621943?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+infectious+diseases&rft.atitle=Investigation+of+the+first+laboratory-acquired+human+cowpox+virus+infection+in+the+United+States.&rft.au=McCollum%2C+Andrea+M%3BAustin%2C+Connie%3BNawrocki%2C+John%3BHowland%2C+Julia%3BPryde%2C+Julie%3BVaid%2C+Awais%3BHolmes%2C+David%3BWeil%2C+M+Ryan%3BLi%2C+Yu%3BWilkins%2C+Kimberly%3BZhao%2C+Hui%3BSmith%2C+Scott+K%3BKarem%2C+Kevin%3BReynolds%2C+Mary+G%3BDamon%2C+Inger+K&rft.aulast=McCollum&rft.aufirst=Andrea&rft.date=2012-07-01&rft.volume=206&rft.issue=1&rft.spage=63&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+infectious+diseases&rft.issn=1537-6613&rft_id=info:doi/10.1093%2Finfdis%2Fjis302 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-10-01 N1 - Date created - 2012-05-28 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1093/infdis/jis302 ER - TY - JOUR T1 - Single-walled carbon nanotube-induced mitotic disruption AN - 1017977316; 16729564 AB - Carbon nanotubes were among the earliest products of nanotechnology and have many potential applications in medicine, electronics, and manufacturing. The low density, small size, and biological persistence of carbon nanotubes create challenges for exposure control and monitoring and make respiratory exposures to workers likely. We have previously shown mitotic spindle aberrations in cultured primary and immortalized human airway epithelial cells exposed to 24, 48 and 96 mu g/cm2 single-walled carbon nanotubes (SWCNT). To investigate mitotic spindle aberrations at concentrations anticipated in exposed workers, primary and immortalized human airway epithelial cells were exposed to SWCNT for 24-72h at doses equivalent to 20 weeks of exposure at the Permissible Exposure Limit for particulates not otherwise regulated. We have now demonstrated fragmented centrosomes, disrupted mitotic spindles and aneuploid chromosome number at those doses. The data further demonstrated multipolar mitotic spindles comprised 95% of the disrupted mitoses. The increased multipolar mitotic spindles were associated with an increased number of cells in the G2 phase of mitosis, indicating a mitotic checkpoint response. Nanotubes were observed in association with mitotic spindle microtubules, the centrosomes and condensed chromatin in cells exposed to 0.024, 0.24, 2.4 and 24 mu g/cm2 SWCNT. Three-dimensional reconstructions showed carbon nanotubes within the centrosome structure. The lower doses did not cause cytotoxicity or reduction in colony formation after 24h; however, after three days, significant cytotoxicity was observed in the SWCNT-exposed cells. Colony formation assays showed an increased proliferation seven days after exposure. Our results show significant disruption of the mitotic spindle by SWCNT at occupationally relevant doses. The increased proliferation that was observed in carbon nanotube-exposed cells indicates a greater potential to pass the genetic damage to daughter cells. Disruption of the centrosome is common in many solid tumors including lung cancer. The resulting aneuploidy is an early event in the progression of many cancers, suggesting that it may play a role in both tumorigenesis and tumor progression. These results suggest caution should be used in the handling and processing of carbon nanotubes. JF - Mutation Research/Genetic Toxicology and Environmental Mutagenesis AU - Sargent, L M AU - Hubbs, A F AU - Young, S-H AU - Kashon, M L AU - Dinu, C Z AU - Salisbury, J L AU - Benkovic, SA AU - Lowry, D T AU - Murray, A R AU - Kisin, E R AU - Siegrist, K J AU - Battelli, L AU - Mastovich, J AU - Sturgeon, J L AU - Bunker, K L AU - Shvedova, A A AU - Reynolds, SH AD - National Institute for Occupational Safety and Health, Morgantown, WV 26505, United States, lqs1@cdc.gov Y1 - 2012/06/14/ PY - 2012 DA - 2012 Jun 14 SP - 28 EP - 37 PB - Elsevier B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 745 IS - 1-2 SN - 1383-5718, 1383-5718 KW - Genetics Abstracts; Toxicology Abstracts KW - Aneuploidy KW - Carbon KW - Cell proliferation KW - Centrosomes KW - Chromatin KW - Chromosome number KW - Colonies KW - Cytotoxicity KW - Epithelial cells KW - G2 phase KW - Lung cancer KW - Microtubules KW - Occupational exposure KW - Respiratory tract KW - Solid tumors KW - Spindles KW - Tumorigenesis KW - nanotechnology KW - nanotubes KW - G 07710:Chemical Mutagenesis & Radiation KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1017977316?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Mutation+Research%2FGenetic+Toxicology+and+Environmental+Mutagenesis&rft.atitle=Single-walled+carbon+nanotube-induced+mitotic+disruption&rft.au=Sargent%2C+L+M%3BHubbs%2C+A+F%3BYoung%2C+S-H%3BKashon%2C+M+L%3BDinu%2C+C+Z%3BSalisbury%2C+J+L%3BBenkovic%2C+SA%3BLowry%2C+D+T%3BMurray%2C+A+R%3BKisin%2C+E+R%3BSiegrist%2C+K+J%3BBattelli%2C+L%3BMastovich%2C+J%3BSturgeon%2C+J+L%3BBunker%2C+K+L%3BShvedova%2C+A+A%3BReynolds%2C+SH&rft.aulast=Sargent&rft.aufirst=L&rft.date=2012-06-14&rft.volume=745&rft.issue=1-2&rft.spage=28&rft.isbn=&rft.btitle=&rft.title=Mutation+Research%2FGenetic+Toxicology+and+Environmental+Mutagenesis&rft.issn=13835718&rft_id=info:doi/10.1016%2Fj.mrgentox.2011.11.017 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2013-01-25 N1 - SubjectsTermNotLitGenreText - Epithelial cells; Microtubules; Aneuploidy; Chromatin; Solid tumors; Tumorigenesis; Chromosome number; Spindles; Cytotoxicity; Colonies; Carbon; Centrosomes; nanotubes; Cell proliferation; Occupational exposure; Lung cancer; nanotechnology; Respiratory tract; G2 phase DO - http://dx.doi.org/10.1016/j.mrgentox.2011.11.017 ER - TY - CPAPER T1 - CDC's Role in Understanding and Preventing Waterborne Infectious Disease T2 - 131st Annual Conference and Exposition of the American Water Works Association (ACE12) AN - 1313028519; 6119942 JF - 131st Annual Conference and Exposition of the American Water Works Association (ACE12) AU - Gargano, Julia Y1 - 2012/06/10/ PY - 2012 DA - 2012 Jun 10 KW - water-borne diseases KW - Infectious diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313028519?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=131st+Annual+Conference+and+Exposition+of+the+American+Water+Works+Association+%28ACE12%29&rft.atitle=CDC%27s+Role+in+Understanding+and+Preventing+Waterborne+Infectious+Disease&rft.au=Gargano%2C+Julia&rft.aulast=Gargano&rft.aufirst=Julia&rft.date=2012-06-10&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=131st+Annual+Conference+and+Exposition+of+the+American+Water+Works+Association+%28ACE12%29&rft.issn=&rft_id=info:doi/ L2 - http://apps.awwa.org/ebusmain/default.aspx?tabid=265&viewer=dates&meetingid=A12 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - JOUR T1 - The influence of perceptions of HIV infection, care, and identity on care entry AN - 1315886617; 201302336 AB - The benefits of accessing HIV care after diagnosis (e.g., improved clinical outcomes and reduced transmission) are well established. However, many persons who are aware that they are HIV infected have never received HIV medical care. During 2008-2010, we conducted 43 in-depth interviews in three health department jurisdictions among adults who had received an HIV diagnosis but who had never accessed HIV medical care. Respondents were selected from the HIV/AIDS Reporting System, a population-based surveillance system. We explored how respondents perceived HIV infection and HIV medical care. Most respondents associated HIV with death. Many respondents said that HIV medical care was not necessary until one is sick. Further, we explored how these perceptions may have conflicted with one's identity and thus served as barriers to timely care entry. Most respondents perceived themselves as healthy. All respondents acknowledged their HIV serostatus, but many did not self-identify as HIV-positive. Several respondents expressed that they were not ready to receive HIV care immediately but felt that they would eventually attempt to access care. Some stated that they needed time to accept their HIV diagnosis before entering care. To improve timely linkage to care, we suggest that during the posttest counseling session and subsequent linkage-to-care activities, counselors and service providers discuss patient perceptions of HIV, particularly to address beliefs that HIV infection is a "death sentence" or that HIV care is necessary only for those who exhibit symptoms. Adapted from the source document. JF - AIDS Care AU - Fagan, Jennifer L AU - Beer, Linda AU - Garland, Pamela AU - Valverde, Eduardo AU - Courogen, Maria AU - Hillman, Daniel AU - Brady, Kathleen AU - Bertolli, Jeanne AD - Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA jfagan@cdc.gov Y1 - 2012/06// PY - 2012 DA - June 2012 SP - 737 EP - 743 PB - Taylor & Francis, Abingdon UK VL - 24 IS - 6 SN - 0954-0121, 0954-0121 KW - Perceptions KW - Diagnosis KW - Health care KW - Identity KW - Infection KW - HIV KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1315886617?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+Care&rft.atitle=The+influence+of+perceptions+of+HIV+infection%2C+care%2C+and+identity+on+care+entry&rft.au=Fagan%2C+Jennifer+L%3BBeer%2C+Linda%3BGarland%2C+Pamela%3BValverde%2C+Eduardo%3BCourogen%2C+Maria%3BHillman%2C+Daniel%3BBrady%2C+Kathleen%3BBertolli%2C+Jeanne&rft.aulast=Fagan&rft.aufirst=Jennifer&rft.date=2012-06-01&rft.volume=24&rft.issue=6&rft.spage=737&rft.isbn=&rft.btitle=&rft.title=AIDS+Care&rft.issn=09540121&rft_id=info:doi/10.1080%2F09540121.2011.630360 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2013-03-01 N1 - Last updated - 2016-09-27 N1 - CODEN - AIDCEF N1 - SubjectsTermNotLitGenreText - HIV; Health care; Perceptions; Diagnosis; Infection; Identity DO - http://dx.doi.org/10.1080/09540121.2011.630360 ER - TY - JOUR T1 - Characteristics of parents receiving counseling from child's doctor to limit child's sugar drink consumption AN - 1038112393; 201223243 AB - Background Due to limited information on sugar drink counseling, characteristics of parents who reported ever receiving counseling from a child's doctor to limit a child's sugar drink intake were examined. Methods This cross-sectional analysis was conducted on a convenient sample of 1570 US parents (aged >=18 years) using the 2009 HealthStyles Survey. The outcome measure was parents with children aged =$60 000, OR = 2.12; 95% CI = 1.33, 3.38) and parents who agreed with 'enjoying learning about health issues' (versus disagree, OR = 2.43; 95% CI = 1.36, 4.36). Age, race/ethnicity, education and marital status were not significantly associated with receiving counseling. Conclusions Few parents reported ever receiving counseling from a child's doctor, and we found a few differences among those reporting sugar drink counseling. Adapted from the source document. JF - Journal of Public Health AU - Park, Sohyun AU - Sherry, Bettylou AU - Blanck, Heidi M AD - Division of Nutrition, Physical Activity and Obesity, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA spark3@cdc.gov Y1 - 2012/06// PY - 2012 DA - June 2012 SP - 228 EP - 235 PB - Oxford University Press VL - 34 IS - 2 SN - 1741-3842, 1741-3842 KW - children doctor nutrition counseling parents sugar drinks KW - Sugar KW - Drinks KW - Doctors KW - Counselling KW - Parents KW - Confidence intervals KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1038112393?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Public+Health&rft.atitle=Characteristics+of+parents+receiving+counseling+from+child%27s+doctor+to+limit+child%27s+sugar+drink+consumption&rft.au=Park%2C+Sohyun%3BSherry%2C+Bettylou%3BBlanck%2C+Heidi+M&rft.aulast=Park&rft.aufirst=Sohyun&rft.date=2012-06-01&rft.volume=34&rft.issue=2&rft.spage=228&rft.isbn=&rft.btitle=&rft.title=Journal+of+Public+Health&rft.issn=17413842&rft_id=info:doi/10.1093%2Fpubmed%2Ffdr071 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2012-09-01 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Counselling; Parents; Drinks; Doctors; Sugar; Confidence intervals DO - http://dx.doi.org/10.1093/pubmed/fdr071 ER - TY - JOUR T1 - Guillain-Barre Syndrome During the 2009-2010 H1N1 Influenza Vaccination Campaign: Population-based Surveillance Among 45 Million Americans AN - 1028035849; 16838102 AB - Because of widespread distribution of the influenza A (H1N1) 2009 monovalent vaccine (pH1N1 vaccine) and the prior association between Guillain-Barre syndrome (GBS) and the 1976 H1N1 influenza vaccine, enhanced surveillance was implemented to estimate the magnitude of any increased GBS risk following administration of pH1N1 vaccine. The authors conducted active, population-based surveillance for incident cases of GBS among 45 million persons residing at 10 Emerging Infections Program sites during October 2009-May 2010; GBS was defined according to published criteria. The authors determined medical and vaccine history for GBS cases through medical record review and patient interviews. The authors used vaccine coverage data to estimate person-time exposed and unexposed to pH1N1 vaccine and calculated age- and sex-adjusted rate ratios comparing GBS incidence in these groups, as well as age- and sex-adjusted numbers of excess GBS cases. The authors received 411 reports of confirmed or probable GBS. The rate of GBS immediately following pH1N1 vaccination was 57% higher than in person-time unexposed to vaccine (adjusted rate ratio = 1.57, 95% confidence interval: 1.02, 2.21), corresponding to 0.74 excess GBS cases per million pH1N1 vaccine doses (95% confidence interval: 0.04, 1.56). This excess risk was much smaller than that observed during the 1976 vaccine campaign and was comparable to some previous seasonal influenza vaccine risk assessments. JF - American Journal of Epidemiology AU - Wise, Matthew E AU - Viray, Melissa AU - Sejvar, James J AU - Lewis, Paige AU - Baughman, Andrew L AU - Connor, Walter AU - Danila, Richard AU - Giambrone, Greg P AU - Hale, Christa AU - Hogan, Brenna C AU - Meek, James I AU - Murphree, Rendi AU - Oh, John Y AU - Reingold, Arthur AU - Tellman, Norisse AU - Conner, Susan M AU - Singleton, James A AU - Lu, Peng-Jun AU - DeStefano, Frank AU - Fridkin, Scott K AU - Vellozzi, Claudia AU - Morgan, Oliver W Y1 - 2012/06/01/ PY - 2012 DA - 2012 Jun 01 SP - 1110 EP - 1119 PB - Oxford University Press, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 175 IS - 11 SN - 0002-9262, 0002-9262 KW - Virology & AIDS Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - Risk assessment KW - Historical account KW - vaccines KW - Data processing KW - medical records KW - Influenza A KW - Infection KW - Vaccination KW - Influenza KW - Sulfur dioxide KW - Guillain-Barre syndrome KW - Reviews KW - Vaccines KW - Seasonal variations KW - V 22490:Miscellaneous KW - R2 23060:Medical and environmental health KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1028035849?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Epidemiology&rft.atitle=Guillain-Barre+Syndrome+During+the+2009-2010+H1N1+Influenza+Vaccination+Campaign%3A+Population-based+Surveillance+Among+45+Million+Americans&rft.au=Wise%2C+Matthew+E%3BViray%2C+Melissa%3BSejvar%2C+James+J%3BLewis%2C+Paige%3BBaughman%2C+Andrew+L%3BConnor%2C+Walter%3BDanila%2C+Richard%3BGiambrone%2C+Greg+P%3BHale%2C+Christa%3BHogan%2C+Brenna+C%3BMeek%2C+James+I%3BMurphree%2C+Rendi%3BOh%2C+John+Y%3BReingold%2C+Arthur%3BTellman%2C+Norisse%3BConner%2C+Susan+M%3BSingleton%2C+James+A%3BLu%2C+Peng-Jun%3BDeStefano%2C+Frank%3BFridkin%2C+Scott+K%3BVellozzi%2C+Claudia%3BMorgan%2C+Oliver+W&rft.aulast=Wise&rft.aufirst=Matthew&rft.date=2012-06-01&rft.volume=175&rft.issue=11&rft.spage=1110&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Epidemiology&rft.issn=00029262&rft_id=info:doi/10.1093%2Faje%2Fkws196 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-07-01 N1 - Last updated - 2013-11-04 N1 - SubjectsTermNotLitGenreText - Risk assessment; Data processing; Guillain-Barre syndrome; medical records; Influenza A; Vaccines; Infection; Vaccination; Influenza; Historical account; vaccines; Sulfur dioxide; Reviews; Seasonal variations DO - http://dx.doi.org/10.1093/aje/kws196 ER - TY - JOUR T1 - Estimating Design Effect and Calculating Sample Size for Respondent-Driven Sampling Studies of Injection Drug Users in the United States AN - 1373428904; 201305569 AB - Respondent-driven sampling (RDS) has become increasingly popular for sampling hidden populations, including injecting drug users (IDU). However, RDS data are unique and require specialized analysis techniques, many of which remain underdeveloped. RDS sample size estimation requires knowing design effect (DE), which can only be calculated post hoc. Few studies have analyzed RDS DE using real world empirical data. We analyze estimated DE from 43 samples of IDU collected using a standardized protocol. We find the previous recommendation that sample size be at least doubled, consistent with DE = 2, underestimates true DE and recommend researchers use DE = 4 as an alternate estimate when calculating sample size. A formula for calculating sample size for RDS studies among IDU is presented. Researchers faced with limited resources may wish to accept slightly higher standard errors to keep sample size requirements low. Our results highlight dangers of ignoring sampling design in analysis. Adapted from the source document. JF - AIDS and Behavior AU - Wejnert, Cyprian AU - Pham, Huong AU - Krishna, Nevin AU - Le, Binh AU - DiNenno, Elizabeth AD - Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Mailstop E-46, Atlanta, GA, 30333, USA cwejnert@cdc.gov Y1 - 2012/05// PY - 2012 DA - May 2012 SP - 797 EP - 806 PB - Springer, Dordrecht, The Netherlands VL - 16 IS - 4 SN - 1090-7165, 1090-7165 KW - Drug Injection KW - Acquired Immune Deficiency Syndrome KW - United States of America KW - Threat KW - Drug Abuse KW - article KW - 6126: acquired immune deficiency syndrome (AIDS) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1373428904?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocialservices&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Estimating+Design+Effect+and+Calculating+Sample+Size+for+Respondent-Driven+Sampling+Studies+of+Injection+Drug+Users+in+the+United+States&rft.au=Wejnert%2C+Cyprian%3BPham%2C+Huong%3BKrishna%2C+Nevin%3BLe%2C+Binh%3BDiNenno%2C+Elizabeth&rft.aulast=Wejnert&rft.aufirst=Cyprian&rft.date=2012-05-01&rft.volume=16&rft.issue=4&rft.spage=797&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-012-0147-8 LA - English DB - Social Services Abstracts N1 - Date revised - 2013-07-01 N1 - Last updated - 2016-09-28 N1 - CODEN - AIBEFC N1 - SubjectsTermNotLitGenreText - Acquired Immune Deficiency Syndrome; Drug Abuse; United States of America; Drug Injection; Threat DO - http://dx.doi.org/10.1007/s10461-012-0147-8 ER - TY - JOUR T1 - From SARS to 2009 H1N1 Influenza: The Evolution of a Public Health Incident Management System at CDC AN - 1151042662; 2011-307725 AB - The organization of the response to infectious disease outbreaks by public health agencies at the federal, state, and local levels has historically been based on traditional public health functions (e.g., epidemiology, surveillance, laboratory, infection control, and health communications). Federal guidance has established a framework for the management of domestic incidents, including public health emergencies. Therefore, public health agencies have had to find a way to incorporate traditional public health functions into the common response framework of the National Incident Management System. One solution is the development of a Science Section, containing public health functions, that is equivalent to the traditional incident command system sections. Public health agencies experiencing difficulties in developing incident management systems should consider the feasibility and suitability of creating a Science Section to allow a more seamless and effective coordination of a public health response, while remaining consistent with current federal guidance. Adapted from the source document. JF - Public Health Reports AU - Papagiotas, Stephen S AU - Frank, Mark AU - Bruce, Sherrie AU - Posid, Joseph M AD - Centers for Disease Control and Prevention, Office of Infectious Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Division of Preparedness and Emerging Infections spapagiotas@cdc.gov Y1 - 2012/05// PY - 2012 DA - May 2012 SP - 267 EP - 274 PB - Association of Schools of Public Health, Washington DC VL - 127 IS - 3 SN - 0033-3549, 0033-3549 KW - Health conditions and policy - Health and health policy KW - Health conditions and policy - Diseases and disorders KW - Science and technology policy - Science and science policy and research KW - Government - Local and municipal government KW - Law and ethics - Criminal law KW - Government - Internal security KW - Health conditions and policy - Medicine and health care KW - Social conditions and policy - Communication KW - Government - State or regional government KW - Influenza KW - Epidemiology KW - State government KW - Local government KW - Communication KW - Communicable diseases KW - Science KW - Surveillance KW - Public health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1151042662?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Public+Health+Reports&rft.atitle=From+SARS+to+2009+H1N1+Influenza%3A+The+Evolution+of+a+Public+Health+Incident+Management+System+at+CDC&rft.au=Papagiotas%2C+Stephen+S%3BFrank%2C+Mark%3BBruce%2C+Sherrie%3BPosid%2C+Joseph+M&rft.aulast=Papagiotas&rft.aufirst=Stephen&rft.date=2012-05-01&rft.volume=127&rft.issue=3&rft.spage=267&rft.isbn=&rft.btitle=&rft.title=Public+Health+Reports&rft.issn=00333549&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2012-11-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Public health; Influenza; Science; Local government; Surveillance; Communicable diseases; Epidemiology; Communication; State government ER - TY - JOUR T1 - Contact and Fumigant Toxicity of Cyperus rotundus Steam Distillate Constituents and Related Compounds to Insecticide-Susceptible and -Resistant Blattella germanica AN - 1028027898; 16825636 AB - We assessed the toxicity of 17 steam distillate constituents of Cyperus rotundus (L.) rhizome, another seven known compounds of C. rotundus rhizome, and 14 structurally related compounds to females from an insecticide-susceptible KSS strain and two field-collected SEL and DJN colonies of Blattella germanica (L.). High contact + fumigant toxicity to KSS females was produced by p-cymene, nerol, linalool, o-cymene, (S)-(-)-citronellal, (1S)-(-)-camphor, terpinolene, and m-cymene (LD50, 0.29-0.47 mg/cm2). The toxicity of these compounds was virtually identical against females from any of the three strains, even though SEL and DJN females were resistant to six acetylcholinesterase inhibitors and three pyrethroids (resistance ratio, 9-154 and 12-195). These results indicate that the compounds and insecticides do not share a common mode of action or elicit cross-resistance. The test compounds were effective in closed but not in open containers against SEL females, indicating that their route of insecticidal action was largely a result of vapor action. Structure-activity relationship indicates that structural characteristics, such as types of functional groups, appear to play a role in determining the terpenoid toxicities to B. germanica. C. rotundus rhizome steam distillate constituents and related compounds described merit further study as potential fumigants for the control of resistant cockroach populations in light of global efforts to reduce the level of highly toxic synthetic insecticides in indoor environments. JF - Journal of Medical Entomology AU - Chang, Kyu-Sik AU - Shin, E-Hyun AU - Park, Chan AU - Ahn, Young-Joon AD - Division of Medical Entomology, National Institute of Health, Korea Center for Disease Control and Prevention, Osong 363-ungbuk, Republic of Korea., yjahn@snu.ac.kr Y1 - 2012/05// PY - 2012 DA - May 2012 SP - 631 EP - 639 PB - Entomological Society of America, 9301 Annapolis Rd. Lanham MD 20706 United States VL - 49 IS - 3 SN - 0022-2585, 0022-2585 KW - Toxicology Abstracts; Entomology Abstracts KW - terpinolene KW - Linalool KW - Acetylcholinesterase KW - Fumigants KW - Rhizomes KW - Steam KW - Blattella germanica KW - p-Cymene KW - Toxicity KW - Colonies KW - Vapors KW - Insecticides KW - Cyperus rotundus KW - Pyrethroids KW - Structure-activity relationships KW - Cross-resistance KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - X 24330:Agrochemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1028027898?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Medical+Entomology&rft.atitle=Contact+and+Fumigant+Toxicity+of+Cyperus+rotundus+Steam+Distillate+Constituents+and+Related+Compounds+to+Insecticide-Susceptible+and+-Resistant+Blattella+germanica&rft.au=Chang%2C+Kyu-Sik%3BShin%2C+E-Hyun%3BPark%2C+Chan%3BAhn%2C+Young-Joon&rft.aulast=Chang&rft.aufirst=Kyu-Sik&rft.date=2012-05-01&rft.volume=49&rft.issue=3&rft.spage=631&rft.isbn=&rft.btitle=&rft.title=Journal+of+Medical+Entomology&rft.issn=00222585&rft_id=info:doi/10.1603%2FME11060 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-07-01 N1 - Number of references - 30 N1 - Last updated - 2013-08-12 N1 - SubjectsTermNotLitGenreText - terpinolene; Fumigants; Acetylcholinesterase; Linalool; Rhizomes; Steam; Toxicity; p-Cymene; Vapors; Colonies; Insecticides; Pyrethroids; Cross-resistance; Structure-activity relationships; Cyperus rotundus; Blattella germanica DO - http://dx.doi.org/10.1603/ME11060 ER - TY - JOUR T1 - Vector Competence of Culex restuans (Diptera: Culicidae) from Two Regions of Chicago with Low and High Prevalence of West Nile Virus Human Infections AN - 1028022590; 16825653 AB - Vector competence studies for West Nile virus (WNV) were conducted for two Culex (Culex) restuans Theobald populations Edison Park (EP) and Illinois Medical District (IMD), in Chicago, IL. The aim was to determine if there were differences between mosquito populations that contributed to the observed differences in the prevalence of WNV. Percentages of orally infected, disseminated, and transmitting mosquitoes were estimated using a generalized linear mixed effects model including a random effect for family to account for anticipated within-family correlation. Analysis indicated that percentages of infected, disseminated, and transmitting mosquitoes were not significantly different between EP and IMD. The within-family correlation was 0.46 (95% CI 0.28, 0.67), indicating reasonably strong tendency for WNV titers of bodies, saliva, and legs within families to be similar. Overall, our results show that vector competence of Cx. restuans for WNV is not a contributing factor to the observed differences in WNV human cases between the EP and IMD areas of Chicago. JF - Journal of Medical Entomology AU - Mutebi, J-P AU - Swope, B N AU - Doyle AU - Biggerstaff, B J AD - Division of Vector-Borne Diseases (DVBD), Centers for Diseases Control and Prevention (CDC), 3150 Rampart Road, Fort Collins, CO 80521, jmutebi@cdc.gov Y1 - 2012/05// PY - 2012 DA - May 2012 SP - 678 EP - 686 PB - Entomological Society of America, 9301 Annapolis Rd. Lanham MD 20706 United States VL - 49 IS - 3 SN - 0022-2585, 0022-2585 KW - ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Virology & AIDS Abstracts; Entomology Abstracts KW - Culex restuans KW - vector competence KW - WNV KW - Chicago KW - USA, Illinois, Chicago KW - USA, Illinois KW - Vectors KW - Culicidae KW - Hosts KW - Infection KW - Entomology KW - Models KW - Public health KW - Disease transmission KW - Leg KW - Parks KW - Saliva KW - Diptera KW - Aquatic insects KW - West Nile virus KW - Q1 08205:Genetics and evolution KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - Q5 08524:Public health, medicines, dangerous organisms KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1028022590?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Medical+Entomology&rft.atitle=Vector+Competence+of+Culex+restuans+%28Diptera%3A+Culicidae%29+from+Two+Regions+of+Chicago+with+Low+and+High+Prevalence+of+West+Nile+Virus+Human+Infections&rft.au=Mutebi%2C+J-P%3BSwope%2C+B+N%3BDoyle%3BBiggerstaff%2C+B+J&rft.aulast=Mutebi&rft.aufirst=J-P&rft.date=2012-05-01&rft.volume=49&rft.issue=3&rft.spage=678&rft.isbn=&rft.btitle=&rft.title=Journal+of+Medical+Entomology&rft.issn=00222585&rft_id=info:doi/10.1603%2FME11193 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-07-01 N1 - Number of references - 43 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Hosts; Aquatic insects; Entomology; Disease transmission; Public health; Leg; Parks; Vectors; Saliva; Infection; Models; Culicidae; Culex restuans; Diptera; West Nile virus; USA, Illinois, Chicago; USA, Illinois DO - http://dx.doi.org/10.1603/ME11193 ER - TY - JOUR T1 - Medical expenditures attributable to cerebral palsy and intellectual disability among Medicaid-enrolled children AN - 1023094702; 201215547 AB - This study estimated medical expenditures attributable to cerebral palsy (CP) among children enrolled in Medicaid, stratified by the presence of co-occurring intellectual disability (ID), relative to children without CP or ID. The MarketScan Medicaid Multi-State database was used to identify children with CP for 2003-2005 by using the International Classification of Diseases, Ninth Revision; Clinical Modification (ICD-9-CM) code 343.xx. Children with ID were identified for 2005 by using ICD-9-CM code 317.xx-319.xx. Children without CP or ID during the same period served as control subjects. Medical expenditures were estimated for case and control children for 2005. The difference between the average expenditures for children with and without CP was used as a proxy for attributable expenditures for the condition. The attributable expenditures of co-occurring ID were calculated similarly as the difference in average expenditures among children with CP with and without ID. A total of 9927 children with CP were identified. Among them, 2022 (20.3%) children had co-occurring ID recorded in medical claims. Children with CP but without ID incurred medical expenditures that were $15,047 higher than those of control children without CP or ID. By contrast, children with CP and co-occurring ID incurred costs that were $41,664 higher, compared with control children, and $26,617 more than children with CP but without ID. Administrative data from a large, multistate database demonstrated high medical expenditures for publicly insured children with CP. Expenditures approximately tripled for children with CP and co-occurring ID. [Copyright Elsevier B.V.] JF - Research in Developmental Disabilities AU - Kancherla, Vijaya AU - Amendah, Djesika D AU - Grosse, Scott D AU - Yeargin-Allsopp, Marshalyn AU - Braun, Kim Van Naarden AD - Developmental Disabilities Branch, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention Y1 - 2012/05// PY - 2012 DA - May 2012 SP - 832 EP - 840 PB - Elsevier Ltd, The Netherlands VL - 33 IS - 3 SN - 0891-4222, 0891-4222 KW - Cost and cost analysis KW - Cerebral palsy KW - Delivery of health care KW - Intellectual disability KW - Health expenditures KW - Medicaid KW - Databases KW - Expenditure KW - Learning disabilities KW - Children KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1023094702?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Research+in+Developmental+Disabilities&rft.atitle=Medical+expenditures+attributable+to+cerebral+palsy+and+intellectual+disability+among+Medicaid-enrolled+children&rft.au=Kancherla%2C+Vijaya%3BAmendah%2C+Djesika+D%3BGrosse%2C+Scott+D%3BYeargin-Allsopp%2C+Marshalyn%3BBraun%2C+Kim+Van+Naarden&rft.aulast=Kancherla&rft.aufirst=Vijaya&rft.date=2012-05-01&rft.volume=33&rft.issue=3&rft.spage=832&rft.isbn=&rft.btitle=&rft.title=Research+in+Developmental+Disabilities&rft.issn=08914222&rft_id=info:doi/10.1016%2Fj.ridd.2011.12.001 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2012-08-01 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Children; Expenditure; Cerebral palsy; Databases; Medicaid; Learning disabilities DO - http://dx.doi.org/10.1016/j.ridd.2011.12.001 ER - TY - JOUR T1 - Association between Acculturation and Breastfeeding among Hispanic Women: Data from the Pregnancy Risk Assessment and Monitoring System AN - 1020837734; 16598010 AB - Background: Breastfeeding rates are typically higher among Hispanic women; however, they vary by acculturation status in that those more acculturated are less likely to breastfeed than those who are less acculturated. This study examined the association between acculturation and breastfeeding behaviors using population-based data.Methods: Data (N = 8942) from the Pregnancy Risk Assessment Monitoring System (PRAMS) were used for analysis. Acculturation status was determined using self-reported Hispanic ethnicity and the language in which the women responded to the PRAMS survey, either English or Spanish. Hispanic women who responded to the survey in Spanish were categorized as less acculturated than those who responded in English. Breastfeeding indicators used were: initiation, duration to greater than or equal to 10 weeks, and exclusive breastfeeding to greater than or equal to 10 weeks.Results: The prevalence rates of breastfeeding initiation, duration, and exclusive breastfeeding to greater than or equal to 10 weeks were significantly higher among less acculturated than among highly acculturated. More acculturated were less likely to initiate breastfeeding (prevalence ratio [PR] = 0.88; 95% CI, 0.86-0.90), less likely to breastfeed greater than or equal to 10 weeks (PR = 0.77; 95% CI, 0.72-0.82), and less likely to report exclusive breastfeeding to greater than or equal to 10 weeks (PR =,0.70; 95% CI, 0.58-0.85). The relationship between breastfeeding continuation and acculturation persisted after adjusting for covariates in that more acculturated were less likely to breastfeed to greater than or equal to 10 weeks (adjusted prevalence ratio [APR] = 0.81; 95% CI, 0.75-0.87), as did the relationship between exclusivity and acculturation; more acculturated were less likely to report exclusive breastfeeding (APR = 0.69; 95% CI, 0.55-0.87).Conclusions: Breastfeeding promotion efforts must include culturally/linguistically supportive services to assure that women are able to make optimal infant feeding decisions. JF - Journal of Human Lactation AU - Ahluwalia, Indu B AU - D'Angelo, Denise AU - Morrow, Brian AU - McDonald, Jill A AD - Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA Y1 - 2012/05// PY - 2012 DA - May 2012 SP - 167 EP - 173 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU United Kingdom VL - 28 IS - 2 SN - 0890-3344, 0890-3344 KW - Risk Abstracts KW - Breast feeding KW - Ethnic groups KW - Feeding KW - Females KW - Infants KW - Pregnancy KW - Risk assessment KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1020837734?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Human+Lactation&rft.atitle=Association+between+Acculturation+and+Breastfeeding+among+Hispanic+Women%3A+Data+from+the+Pregnancy+Risk+Assessment+and+Monitoring+System&rft.au=Ahluwalia%2C+Indu+B%3BD%27Angelo%2C+Denise%3BMorrow%2C+Brian%3BMcDonald%2C+Jill+A&rft.aulast=Ahluwalia&rft.aufirst=Indu&rft.date=2012-05-01&rft.volume=28&rft.issue=2&rft.spage=167&rft.isbn=&rft.btitle=&rft.title=Journal+of+Human+Lactation&rft.issn=08903344&rft_id=info:doi/10.1177%2F0890334412438403 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-06-01 N1 - Number of references - 27 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - Risk assessment; Feeding; Breast feeding; Females; Ethnic groups; Infants; Pregnancy DO - http://dx.doi.org/10.1177/0890334412438403 ER - TY - JOUR T1 - Rapid molecular identification of Listeria species by use of real-time PCR and high-resolution melting analysis AN - 1011209911; 16548596 AB - Identification of Listeria species via a molecular method is critical for food safety and clinical diagnosis. In this study, an assay integrating real-time quantitative PCR (Q-PCR) with high-resolution melting (HRM) curve analysis was developed and assessed for rapid identification of six Listeria species. The ssrA gene, which encodes a transfer-messenger RNA (tmRNA) is conserved and common to all bacterial phyla, contains a variable domain in Listeria spp. Therefore, Q-PCR and a HRM profile were applied to characterize this gene. Fifty-three Listeria species and 45 non-Listeria species were detected using one primer set, with an accuracy of 100% in reference to conventional methods. There was a 93.3% correction rate to 30 artificially contaminated samples. Thus, Q-PCR with melting profiling analysis proved able to identify Listeria species accurately. Consequently, this study demonstrates that the assay we developed is a functional tool for rapidly identifying six Listeria species, and has the potential for discriminating novel species food safety and epidemiological research. JF - FEMS Microbiology Letters AU - Jin, Dazhi AU - Luo, Yun AU - Zhang, Zheng AU - Fang, Weijia AU - Ye, Julian AU - Wu, Fang AU - Ding, Gangqiang AD - Zhejiang Provincial Center for Disease Control and Prevention Y1 - 2012/05// PY - 2012 DA - May 2012 SP - 72 EP - 80 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 330 IS - 1 SN - 0378-1097, 0378-1097 KW - Microbiology Abstracts B: Bacteriology; Environment Abstracts KW - Melting KW - RNA KW - tmRNA KW - Food KW - Polymerase chain reaction KW - Primers KW - Food contamination KW - Listeria KW - ssrA gene KW - J 02310:Genetics & Taxonomy KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1011209911?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=FEMS+Microbiology+Letters&rft.atitle=Rapid+molecular+identification+of+Listeria+species+by+use+of+real-time+PCR+and+high-resolution+melting+analysis&rft.au=Jin%2C+Dazhi%3BLuo%2C+Yun%3BZhang%2C+Zheng%3BFang%2C+Weijia%3BYe%2C+Julian%3BWu%2C+Fang%3BDing%2C+Gangqiang&rft.aulast=Jin&rft.aufirst=Dazhi&rft.date=2012-05-01&rft.volume=330&rft.issue=1&rft.spage=72&rft.isbn=&rft.btitle=&rft.title=FEMS+Microbiology+Letters&rft.issn=03781097&rft_id=info:doi/10.1111%2Fj.1574-6968.2012.02535.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2013-07-15 N1 - SubjectsTermNotLitGenreText - Melting; RNA; tmRNA; Food; Polymerase chain reaction; Primers; ssrA gene; Food contamination; Listeria DO - http://dx.doi.org/10.1111/j.1574-6968.2012.02535.x ER - TY - JOUR T1 - Characterization of human clinical isolates of Dietzia species previously misidentified as Rhodococcus equi AN - 1011209586; 16540809 AB - In this study, 16 human clinical isolates of Dietzia species previously misidentified as Rhodococcus equi were evaluated using phenotypic methods, including traditional and commercial (API Coryne) biochemical tests, antimicrobial susceptibility testing, and 16S rRNA gene and gyrB gene sequencing. Positive results for both the hydrolysis of adenine and Christie-Atkins-Munch-Petersen (CAMP) reaction allowed for differentiation between the Dietzia isolates and the type strain of Rhodococcus equi; however, traditional and commercial phenotypic profiles could not be used to reliably identify Dietzia species. The analysis of 16S rRNA gene and gyrB gene sequences could discriminate all Dietzia strains from the type strain of R. equi. Most Dietzia species had distinct 16S rRNA gene and gyrB gene sequences; however, the 16S rRNA gene sequences of the type strains of D. schimae and D. cercidiphylli were identical to D. maris and D. natronolimnaea, respectively. Based on comparative sequence analysis, five clinical isolates clustered with D. maris/D. schimae and nine with D. natronolimnaea/D. cercidiphylli. The two remaining isolates were found to be most closely related to the D. cinnamea/D. papillomatosis clade. Even though molecular analyses were not sufficiently discriminative to accurately identify all Dietzia species, the method was able to reliably identify isolates that were previously misidentified by phenotypic methods to the genus level. JF - European Journal of Clinical Microbiology & Infectious Diseases AU - Niwa, H AU - Lasker, BA AU - Hinrikson, H P AU - Franzen, C G AU - Steigerwalt, A G AU - Whitney, A M AU - Brown, J M AD - Bacterial Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention (CDC), Mail Stop G-34, 1600 Clifton Road NE, Atlanta, GA, 30333, USA, jmb6@cdc.gov Y1 - 2012/05// PY - 2012 DA - May 2012 SP - 811 EP - 820 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 31 IS - 5 SN - 0934-9723, 0934-9723 KW - Microbiology Abstracts B: Bacteriology KW - Adenine KW - Antimicrobial agents KW - Clinical isolates KW - Cyclic AMP KW - DNA topoisomerase KW - Differentiation KW - Hydrolysis KW - Papilloma KW - rRNA 16S KW - Dietzia KW - Coryne KW - Rhodococcus equi KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1011209586?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=European+Journal+of+Clinical+Microbiology+%26+Infectious+Diseases&rft.atitle=Characterization+of+human+clinical+isolates+of+Dietzia+species+previously+misidentified+as+Rhodococcus+equi&rft.au=Niwa%2C+H%3BLasker%2C+BA%3BHinrikson%2C+H+P%3BFranzen%2C+C+G%3BSteigerwalt%2C+A+G%3BWhitney%2C+A+M%3BBrown%2C+J+M&rft.aulast=Niwa&rft.aufirst=H&rft.date=2012-05-01&rft.volume=31&rft.issue=5&rft.spage=811&rft.isbn=&rft.btitle=&rft.title=European+Journal+of+Clinical+Microbiology+%26+Infectious+Diseases&rft.issn=09349723&rft_id=info:doi/10.1007%2Fs10096-011-1379-7 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2012-05-18 N1 - SubjectsTermNotLitGenreText - Clinical isolates; Differentiation; Cyclic AMP; Adenine; DNA topoisomerase; Papilloma; Hydrolysis; rRNA 16S; Antimicrobial agents; Coryne; Dietzia; Rhodococcus equi DO - http://dx.doi.org/10.1007/s10096-011-1379-7 ER - TY - JOUR T1 - Dengue Deaths in Puerto Rico: Lessons Learned from the 2007 Epidemic AN - 1020837529; 16665314 AB - Dengue is a major public health problem in the tropics and subtropics; an estimated 50 million cases occur annually and 40 percent of the world's population lives in areas with dengue virus (DENV) transmission. Dengue has a wide range of clinical presentations from an undifferentiated acute febrile illness, classic dengue fever, to severe dengue (i.e., dengue hemorrhagic fever or dengue shock syndrome). About 5% of patients develop severe dengue, which is more common with second or subsequent infections. No vaccines are available to prevent dengue, and there are no specific antiviral treatments for patients with dengue. However, early recognition of shock and intensive supportive therapy can reduce risk of death from similar to 10% to less than 1% among severe dengue cases. Reviewing dengue deaths is one means to identify issues in clinical management. These findings can be used to develop healthcare provider education to minimize dengue morbidity and mortality. JF - PLoS Neglected Tropical Diseases AU - Tomashek, Kay M AU - Gregory, Christopher J AU - Rivera Sanchez, Aidsa AU - Bartek, Matthew A AU - Garcia Rivera, Enid J AU - Hunsperger, Elizabeth AU - Munoz-Jordan, Jorge L AU - Sun, Wellington AD - Dengue Branch, Division of Vector-Borne Diseases (DVBD), National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), Centers for Disease Control and Prevention (CDC), San Juan, Puerto Rico Y1 - 2012/04/17/ PY - 2012 DA - 2012 Apr 17 PB - Public Library of Science, 185 Berry Street San Francisco CA 94107 United States VL - 6 IS - 4 SN - 1935-2727, 1935-2727 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Virology & AIDS Abstracts KW - Dengue virus KW - Mortality KW - Symptoms KW - Human diseases KW - Epidemics KW - Disease control KW - Therapy KW - Infection KW - Morbidity KW - Public health KW - Dengue hemorrhagic fever KW - Education KW - Shock KW - ASW, Caribbean Sea, Greater Antilles, Puerto Rico KW - Dengue KW - Vaccines KW - Mortality causes KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1020837529?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=PLoS+Neglected+Tropical+Diseases&rft.atitle=Dengue+Deaths+in+Puerto+Rico%3A+Lessons+Learned+from+the+2007+Epidemic&rft.au=Tomashek%2C+Kay+M%3BGregory%2C+Christopher+J%3BRivera+Sanchez%2C+Aidsa%3BBartek%2C+Matthew+A%3BGarcia+Rivera%2C+Enid+J%3BHunsperger%2C+Elizabeth%3BMunoz-Jordan%2C+Jorge+L%3BSun%2C+Wellington&rft.aulast=Tomashek&rft.aufirst=Kay&rft.date=2012-04-17&rft.volume=6&rft.issue=4&rft.spage=&rft.isbn=&rft.btitle=&rft.title=PLoS+Neglected+Tropical+Diseases&rft.issn=19352727&rft_id=info:doi/10.1371%2Fjournal.pntd.0001614 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-06-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Symptoms; Education; Human diseases; Epidemics; Therapy; Disease control; Vaccines; Mortality causes; Public health; Mortality; Dengue hemorrhagic fever; Shock; Dengue; Infection; Morbidity; Dengue virus; ASW, Caribbean Sea, Greater Antilles, Puerto Rico DO - http://dx.doi.org/10.1371/journal.pntd.0001614 ER - TY - JOUR T1 - Caught Between the "Soft" and "Hard" Arms of the State: A Conceptual Apparatus for Situating the Formative Role of Drug User Organizations in National Policy-Making and Local Service Delivery -A Commentary AN - 1449098107; 201325427 AB - Comments on a series of papers in the same journal issue, 'Drug user organizations in the Nordic countries--local, national, and international dimensions.'; 'The Injection Support Team: a peer-driven program to address unsafe injecting in a Canadian setting.'; 'Collective empowerment while creating knowledge: a description of a community-based participatory research project with drug users in Bangkok, Thailand.'; and 'Implementation of harm reduction toward crack users in Brazil: barriers and achievements.'. Adapted from the source document. JF - Substance Use & Misuse AU - Zibbell, Jon E Y1 - 2012/04// PY - 2012 DA - April 2012 SP - 558 EP - 565 PB - Informa Healthcare, New York NY VL - 47 IS - 5 SN - 1082-6084, 1082-6084 KW - Thailand KW - Brazil KW - Drug addicts KW - Policy making KW - Empowerment KW - Harm reduction KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1449098107?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Substance+Use+%26+Misuse&rft.atitle=Caught+Between+the+%22Soft%22+and+%22Hard%22+Arms+of+the+State%3A+A+Conceptual+Apparatus+for+Situating+the+Formative+Role+of+Drug+User+Organizations+in+National+Policy-Making+and+Local+Service+Delivery+-A+Commentary&rft.au=Zibbell%2C+Jon+E&rft.aulast=Zibbell&rft.aufirst=Jon&rft.date=2012-04-01&rft.volume=47&rft.issue=5&rft.spage=558&rft.isbn=&rft.btitle=&rft.title=Substance+Use+%26+Misuse&rft.issn=10826084&rft_id=info:doi/10.3109%2F10826084.2012.644125 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2013-11-01 N1 - Last updated - 2016-09-27 N1 - CODEN - SUMIFL N1 - SubjectsTermNotLitGenreText - Drug addicts; Empowerment; Brazil; Policy making; Thailand; Harm reduction DO - http://dx.doi.org/10.3109/10826084.2012.644125 ER - TY - JOUR T1 - Low Influenza Vaccination Rates Among Child Care Workers in the United States: Assessing Knowledge, Attitudes, and Behaviors AN - 1023035268; 2011-230330 AB - Influenza can spread quickly among children and caregivers in child day care settings. Vaccination is the most effective method to prevent influenza. We determined 2009 pandemic influenza A (H1N1) (pH1N1) and seasonal influenza vaccination rates during the 2009-2010 influenza season among child care center employees, assessed knowledge and attitudes regarding the vaccines, and determined factors associated with vaccine receipt. Using a cross-sectional study design, from January 30-March 1, 2010, we surveyed 384 (95%) of 403 employees at 32 licensed child centers in the United States about personal and work characteristics, vaccine receipt, and knowledge and attitudes regarding each vaccine. Forty-five (11%) and eighty five (22%) respondents reported receiving the pH1N1 and seasonal influenza vaccines, respectively. The most common reasons cited for not getting either vaccine were "I don't think I need the vaccine," "I don't think the vaccine will keep me from getting the flu," and "the vaccine is not safe." Factors independently associated with receipt of either vaccine included belief in its efficacy, having positive attitudes towards it, and feeling external pressure to get it. Child care center employees had low rates of pH1N1 and seasonal influenza vaccination largely due to misconceptions about the need for and efficacy of the vaccine. Public health messages should address misconceptions about vaccines, and employers should consider methods to maximize influenza vaccination of employees as part of a comprehensive influenza prevention program. Adapted from the source document. JF - Journal of Community Health AU - Perio, Marie A AU - Wiegand, Douglas M AU - Evans, Stefanie M AD - Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health mdeperio@cdc.gov Y1 - 2012/04// PY - 2012 DA - April 2012 SP - 272 EP - 281 PB - Springer, New York NY VL - 37 IS - 2 SN - 0094-5145, 0094-5145 KW - Health conditions and policy - Health and health policy KW - Health conditions and policy - Medicine and health care KW - Health conditions and policy - Diseases and disorders KW - Labor conditions and policy - Work and labor KW - Social conditions and policy - Marriage and family life KW - Business and service sector - Personal and housekeeping services KW - Population groups, population policy, and demographics - Children and youth KW - United States KW - Influenza KW - Caregivers KW - Employees KW - Children KW - Child care KW - Vaccination and vaccines KW - Public health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1023035268?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Community+Health&rft.atitle=Low+Influenza+Vaccination+Rates+Among+Child+Care+Workers+in+the+United+States%3A+Assessing+Knowledge%2C+Attitudes%2C+and+Behaviors&rft.au=Perio%2C+Marie+A%3BWiegand%2C+Douglas+M%3BEvans%2C+Stefanie+M&rft.aulast=Perio&rft.aufirst=Marie&rft.date=2012-04-01&rft.volume=37&rft.issue=2&rft.spage=272&rft.isbn=&rft.btitle=&rft.title=Journal+of+Community+Health&rft.issn=00945145&rft_id=info:doi/10.1007%2Fs10900-011-9478-z LA - English DB - PAIS Index N1 - Date revised - 2012-07-01 N1 - Last updated - 2016-09-28 N1 - CODEN - JCMHBR N1 - SubjectsTermNotLitGenreText - Public health; Vaccination and vaccines; Influenza; Employees; Child care; United States; Caregivers; Children DO - http://dx.doi.org/10.1007/s10900-011-9478-z ER - TY - JOUR T1 - Nevirapine-Associated Hepatotoxicity and Rash among HIV-Infected Pregnant Women in Kenya AN - 1017968812; 16577611 AB - Background: Few studies have evaluated the risk of nevirapine (NVP)-associated hepatotoxicity among HIV-infected pregnant women with a CD4 count greater than or equal to 250 cells/mm3. Methods: We enrolled HIV-infected pregnant Kenyan women who initiated triple antiretroviral therapy (ART) at 34 weeks gestation. We compared the rates of severe hepatotoxicity (grades 3-4 hepatotoxicity) and rash-associated hepatotoxicity (rash with greater than or equal to grade 2 hepatotoxicity) with NVP and nelfinavir (NFV), respectively. Results: We initiated triple ART in 522 pregnant women; severe hepatotoxicity and rash-associated hepatotoxicity occurred in 14 (3%) and 9 (2%) women, respectively. Women who initiated NVP had higher rates of severe hepatotoxicity (5% vs 1%; P = .03) and rash-associated hepatotoxicity (4% vs 0%; P = .003) when compared with NFV. Among women who initiated NVP (n = 254), a baseline CD4 count greater than or equal to 250 cells/mm3 was not associated with severe hepatotoxicity (5% vs 3%; P = .52) or rash-associated hepatotoxicity (4% vs 3%; P = .69). Conclusion: Nevirapine use but not CD4 count greater than or equal to 250 cells/mm3 was associated with hepatotoxicity. JF - Journal of the International Association of Physicians in AIDS Care (JIAPAC) AU - Peters, Philip J AU - Polle, Nicholas AU - Zeh, Clement AU - Masaba, Rose AU - Borkowf, Craig B AU - Oyaro, Boaz AU - Omolo, Paul AU - Ogindo, Paul AU - Ndivo, Richard AU - Angira, Frank AU - Lando, Richard AU - Fowler, Mary Glenn AU - Weidle, Paul J AU - Thomas, Timothy K AD - Centers for Disease Control and Prevention, Atlanta, GA, USA, pjpeters@cdc.gov Y1 - 2012/04// PY - 2012 DA - Apr 2012 SP - 142 EP - 149 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU United Kingdom VL - 11 IS - 2 SN - 1545-1097, 1545-1097 KW - Virology & AIDS Abstracts; Risk Abstracts KW - Acquired immune deficiency syndrome KW - CD4 antigen KW - Exanthema KW - Females KW - Gestation KW - Nelfinavir KW - Nevirapine KW - Pregnancy KW - antiretroviral agents KW - antiretroviral therapy KW - hepatotoxicity KW - Kenya KW - Human immunodeficiency virus KW - V 22360:AIDS and HIV KW - R2 23010:General: Models, forecasting UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1017968812?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+International+Association+of+Physicians+in+AIDS+Care+%28JIAPAC%29&rft.atitle=Nevirapine-Associated+Hepatotoxicity+and+Rash+among+HIV-Infected+Pregnant+Women+in+Kenya&rft.au=Peters%2C+Philip+J%3BPolle%2C+Nicholas%3BZeh%2C+Clement%3BMasaba%2C+Rose%3BBorkowf%2C+Craig+B%3BOyaro%2C+Boaz%3BOmolo%2C+Paul%3BOgindo%2C+Paul%3BNdivo%2C+Richard%3BAngira%2C+Frank%3BLando%2C+Richard%3BFowler%2C+Mary+Glenn%3BWeidle%2C+Paul+J%3BThomas%2C+Timothy+K&rft.aulast=Peters&rft.aufirst=Philip&rft.date=2012-04-01&rft.volume=11&rft.issue=2&rft.spage=142&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+International+Association+of+Physicians+in+AIDS+Care+%28JIAPAC%29&rft.issn=15451097&rft_id=info:doi/10.1177%2F1545109711423445 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Number of references - 35 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - Exanthema; Nevirapine; CD4 antigen; Gestation; antiretroviral therapy; Nelfinavir; hepatotoxicity; Pregnancy; Acquired immune deficiency syndrome; antiretroviral agents; Females; Human immunodeficiency virus; Kenya DO - http://dx.doi.org/10.1177/1545109711423445 ER - TY - JOUR T1 - Increasing directly observed therapy related to improved tuberculosis treatment outcomes in Taiwan AN - 1011216558; 16564181 AB - SETTING: Directly observed therapy (DOT) is a core element of tuberculosis (TB) care and control efforts. In Taiwan, DOT was implemented in 2006, when the Stop TB Strategy was adopted as a national policy. OBJECTIVE: To quantify DOT among patients on anti-tuberculosis treatment and measure the association between proportion of DOT and TB treatment outcomes at a national level in Taiwan. DESIGN: We analyzed data prospectively collected on all new pulmonary TB cases reported to the national Web-based registry between 1 January 2007 and 30 June 2008. We compared treatment outcomes and proportion of DOT in multivariable analyses. RESULTS: Among 11528 patients initiating anti-tuberculosis treatment, the proportion of days during which an official DOT observer witnessed treatment was >60% for 5150 (45%) patients and less than or equal to =60% for 4601 (40%) patients, whereas for 1777 (15%) patients no days of DOT were recorded. Being older, male, having positive bacteriology results and a non-World Health Organization recommended treatment regimen at baseline were independently related to unsuccessful treatment outcomes and mortality. A dose-response effect was found between proportion of DOT and these outcomes. CONCLUSION: These findings highlight the importance of ensuring universal DOT in improving treatment outcomes among new pulmonary TB patients. JF - International Journal of Tuberculosis and Lung Disease AU - Bloss, E AU - Chan, P-C AU - Cheng, N-W AU - Wang, K-F AU - Yang, S-L AU - Cegielski, P AD - Division of Tuberculosis Elimination, International Research and Programs Branch, CDC, 1600 Clifton Road, MS E-10, Atlanta, GA 30333, USA, dpu2@cdc.gov Y1 - 2012/04// PY - 2012 DA - Apr 2012 SP - 462 EP - 467 PB - International Union Against Tuberculosis and Lung Disease VL - 16 IS - 4 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology KW - Mortality KW - Data processing KW - Mycobacterium KW - Dose-response effects KW - Lung diseases KW - Tuberculosis KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1011216558?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Increasing+directly+observed+therapy+related+to+improved+tuberculosis+treatment+outcomes+in+Taiwan&rft.au=Bloss%2C+E%3BChan%2C+P-C%3BCheng%2C+N-W%3BWang%2C+K-F%3BYang%2C+S-L%3BCegielski%2C+P&rft.aulast=Bloss&rft.aufirst=E&rft.date=2012-04-01&rft.volume=16&rft.issue=4&rft.spage=462&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Mortality; Data processing; Dose-response effects; Lung diseases; Tuberculosis; Mycobacterium ER - TY - JOUR T1 - Household Demographics and Perceived Insufficient Sleep Among US Adults AN - 1008832900; 16433527 AB - It has become increasingly recognized that insufficient sleep is associated with adverse health outcomes. Studies have observed that sleep duration and daytime sleepiness varies by sex and marital status. Few studies have examined the impact of the number of children on sleep. To evaluate the association of marital status and number of children with insufficient sleep and in a large national sample. We analyzed data from the 2008 Behavioral Risk Factor Surveillance System (BRFSS) survey, a population-based telephone survey of non-institutionalized US adults (N = 395,407), in which respondents were asked, "During the past 30 days, for about how many days have you felt you did not get enough rest or sleep?" We used sex-specific, multivariate logistic regression analyses to assess the associations of marital status (married, previously married, never married) and the number of children in the household with frequent insufficient sleep ( greater than or equal to 14 days in past 30 days) after adjusting for age, race/ethnicity, and education. In this study population, 23% were never married, 60% were married, and 17% were previously married. Forty-three percent reported having children aged <18 years in the household. Married men (24.3%) were less likely to report frequent insufficient sleep than never married men (28.0%) or previously married men (28.8%). Never married women (33.4%) were more likely to report frequent insufficient sleep than currently married (29.0%) or previously married women (29.0%). The likelihood of frequent insufficient sleep increased in a linear fashion with the number of children in the household for all subgroups (P < 0.05) except among never married men. These findings suggest that the presence of children in the household often increases the frequency of insufficient rest or sleep among the adults with whom they reside. Thus, health care providers may wish to consider the presence of children under 18 years of age a potential "risk factor" for insufficient sleep when counseling adults in the household about the importance of sleep to overall health. JF - Journal of Community Health AU - Chapman, Daniel P AU - Wheaton, Anne G AU - Perry, Geraldine S AU - Sturgis, Stephanie L AU - Strine, Tara W AU - Croft, Janet B AD - Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway NE Mailstop K-67, Atlanta, GA, 30041, USA, DChapman@cdc.gov Y1 - 2012/04// PY - 2012 DA - Apr 2012 SP - 344 EP - 349 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 37 IS - 2 SN - 0094-5145, 0094-5145 KW - Health & Safety Science Abstracts; Risk Abstracts KW - Age KW - Children KW - Education KW - Ethnic groups KW - Health care KW - Households KW - Perception KW - Risk factors KW - households KW - marriage KW - USA KW - R2 23060:Medical and environmental health KW - H 0500:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1008832900?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Community+Health&rft.atitle=Household+Demographics+and+Perceived+Insufficient+Sleep+Among+US+Adults&rft.au=Chapman%2C+Daniel+P%3BWheaton%2C+Anne+G%3BPerry%2C+Geraldine+S%3BSturgis%2C+Stephanie+L%3BStrine%2C+Tara+W%3BCroft%2C+Janet+B&rft.aulast=Chapman&rft.aufirst=Daniel&rft.date=2012-04-01&rft.volume=37&rft.issue=2&rft.spage=344&rft.isbn=&rft.btitle=&rft.title=Journal+of+Community+Health&rft.issn=00945145&rft_id=info:doi/10.1007%2Fs10900-011-9451-x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-01 N1 - Last updated - 2012-06-29 N1 - SubjectsTermNotLitGenreText - Education; Age; households; Health care; Perception; Households; Risk factors; marriage; Children; Ethnic groups; USA DO - http://dx.doi.org/10.1007/s10900-011-9451-x ER - TY - JOUR T1 - Homophobia and Racism Experienced by Latino Men Who Have Sex with Men in the United States: Correlates of Exposure and Associations with HIV Risk Behaviors AN - 1008829575; 16505616 AB - Using cross-sectional data collected from 1081 Latino men who have sex with men (MSM) recruited with respondent-driven sampling (RDS) techniques from Los Angeles and New York, we examined the extent to which Latino MSM reported exposure to social discrimination (i.e., experienced both homophobia and racism, homophobia only, racism only, or neither homophobia nor racism). More than 40% of respondents experienced both homophobia and racism in the past 12 months. Los Angeles participants, those with lower income, and those who reported being HIV-positive were more likely to report experiencing both types of social discrimination. Adjusting for potential confounders, men exposed to both homophobia and racism were more likely than men exposed to neither form of discrimination to report unprotected receptive anal intercourse with a casual sex partner (AOR = 1.92, 95% CI, 1.18-3.24) and binge drinking (AOR = 1.42, 95% CI, 1.02-1.98). Our findings suggest the presence of a syndemic of adverse social experiences and call for more intervention research to address both homophobia and racism experienced among Latino MSM in the United States. JF - AIDS and Behavior AU - Mizuno, Yuko AU - Borkowf, Craig AU - Millett, Gregorio A AU - Bingham, Trista AU - Ayala, George AU - Stueve, Ann AD - Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road, NE Mail Stop E37, Atlanta, GA, 30333, USA, ymizuno@cdc.gov Y1 - 2012/04// PY - 2012 DA - Apr 2012 SP - 724 EP - 735 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 16 IS - 3 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - Acquired immune deficiency syndrome KW - Anal sex KW - Binge drinking KW - Data processing KW - Discrimination KW - Drinking KW - Ethnic groups KW - Homosexuality KW - Human immunodeficiency virus KW - Income KW - Intervention KW - Sampling KW - Sex KW - Sexual behavior KW - Social interactions KW - USA, California, Los Angeles KW - USA, New York KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1008829575?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Homophobia+and+Racism+Experienced+by+Latino+Men+Who+Have+Sex+with+Men+in+the+United+States%3A+Correlates+of+Exposure+and+Associations+with+HIV+Risk+Behaviors&rft.au=Mizuno%2C+Yuko%3BBorkowf%2C+Craig%3BMillett%2C+Gregorio+A%3BBingham%2C+Trista%3BAyala%2C+George%3BStueve%2C+Ann&rft.aulast=Mizuno&rft.aufirst=Yuko&rft.date=2012-04-01&rft.volume=16&rft.issue=3&rft.spage=724&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-011-9967-1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-01 N1 - Last updated - 2012-05-18 N1 - SubjectsTermNotLitGenreText - Drinking; Data processing; Sampling; Social interactions; Sex; Binge drinking; Acquired immune deficiency syndrome; Human immunodeficiency virus; Intervention; Discrimination; Anal sex; Homosexuality; Sexual behavior; Ethnic groups; Income; USA, California, Los Angeles; USA, New York DO - http://dx.doi.org/10.1007/s10461-011-9967-1 ER - TY - CPAPER T1 - Prenatal Cytogenetic Diagnosis, Elective Termination, and Prevalence of Trisomy 21 by Maternal Race- Ethnicity, Metropolitan Atlanta, 1996-2005 T2 - 2012 ACMG Annual Clinical Genetics Meeting AN - 1313019726; 6108088 JF - 2012 ACMG Annual Clinical Genetics Meeting AU - Jackson, Jodi AU - Crider, Krista AU - Rasmussen, Sonja AU - Cragan, Janet AU - Olney, Richard Y1 - 2012/03/27/ PY - 2012 DA - 2012 Mar 27 KW - USA, Georgia, Atlanta KW - Prenatal experience KW - Ethnic groups KW - Trisomy KW - Cytogenetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313019726?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2012+ACMG+Annual+Clinical+Genetics+Meeting&rft.atitle=Prenatal+Cytogenetic+Diagnosis%2C+Elective+Termination%2C+and+Prevalence+of+Trisomy+21+by+Maternal+Race-+Ethnicity%2C+Metropolitan+Atlanta%2C+1996-2005&rft.au=Jackson%2C+Jodi%3BCrider%2C+Krista%3BRasmussen%2C+Sonja%3BCragan%2C+Janet%3BOlney%2C+Richard&rft.aulast=Jackson&rft.aufirst=Jodi&rft.date=2012-03-27&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2012+ACMG+Annual+Clinical+Genetics+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://submissions.miracd.com/acmg2012/Itinerary/SearchResultsProgram.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - JOUR T1 - Human teratogens update 2011: can we ensure safety during pregnancy? AN - 927991084; 22328359 AB - Anniversaries of the identification of three human teratogens (i.e., rubella virus in 1941, thalidomide in 1961, and diethylstilbestrol in 1971) occurred in 2011. These experiences highlight the critical role that scientists with an interest in teratology play in the identification of teratogenic exposures as the basis for developing strategies for prevention of those exposures and the adverse outcomes associated with them. However, an equally important responsibility for teratologists is to evaluate whether medications and vaccines are safe for use during pregnancy so informed decisions about disease treatment and prevention during pregnancy can be made. Several recent studies have examined the safety of medications during pregnancy, including antiviral medications used to treat herpes simplex and zoster, proton pump inhibitors used to treat gastroesophageal reflux, and newer-generation antiepileptic medications used to treat seizures and other conditions. Despite the large numbers of pregnant women included in these studies and the relatively reassuring results, the question of whether these medications are teratogens remains. In addition, certain vaccines are recommended during pregnancy to prevent infections in mothers and infants, but clinical trials to test these vaccines typically exclude pregnant women; thus, evaluation of their safety depends on observational studies. For pregnant women to receive optimal care, we need to define the data needed to determine whether a medication or vaccine is "safe" for use during pregnancy. In the absence of adequate, well-controlled data, it will often be necessary to weigh the benefits of medications or vaccines with potential risks to the embryo or fetus. Copyright © 2012 Wiley Periodicals, Inc. JF - Birth defects research. Part A, Clinical and molecular teratology AU - Rasmussen, Sonja A AD - Centers for Disease Control and Prevention, Atlanta, Georgia 300333, USA. skr9@cdc.gov Y1 - 2012/03// PY - 2012 DA - March 2012 SP - 123 EP - 128 VL - 94 IS - 3 KW - Pharmaceutical Preparations KW - 0 KW - Teratogens KW - Vaccines KW - Index Medicus KW - Pharmaceutical Preparations -- administration & dosage KW - Humans KW - Teratology KW - Infant, Newborn KW - Female KW - Risk Assessment KW - Pregnancy Outcome KW - Pregnancy KW - Vaccines -- adverse effects KW - Prenatal Exposure Delayed Effects -- prevention & control KW - Prenatal Exposure Delayed Effects -- chemically induced KW - Pregnancy Complications -- prevention & control KW - Drug-Related Side Effects and Adverse Reactions KW - Pregnancy Complications -- drug therapy KW - Teratogens -- toxicity KW - Abnormalities, Drug-Induced -- etiology KW - Vaccines -- therapeutic use KW - Abnormalities, Drug-Induced -- prevention & control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/927991084?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Birth+defects+research.+Part+A%2C+Clinical+and+molecular+teratology&rft.atitle=Human+teratogens+update+2011%3A+can+we+ensure+safety+during+pregnancy%3F&rft.au=Rasmussen%2C+Sonja+A&rft.aulast=Rasmussen&rft.aufirst=Sonja&rft.date=2012-03-01&rft.volume=94&rft.issue=3&rft.spage=123&rft.isbn=&rft.btitle=&rft.title=Birth+defects+research.+Part+A%2C+Clinical+and+molecular+teratology&rft.issn=1542-0760&rft_id=info:doi/10.1002%2Fbdra.22887 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-07-10 N1 - Date created - 2012-03-13 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1002/bdra.22887 ER - TY - JOUR T1 - Blood mercury levels among fish consumers residing in areas with high environmental burden. AN - 919649802; 22153999 AB - Mercury is a ubiquitous, persistent toxicant found in the environment. In water, mercury bioaccumulates up the food chain and leads to high concentrations in fish. Consumption of contaminated fish is the major source of exposure to mercury in the US. The objective of this study was to enroll persons living in areas selected by the Environmental Protection Agency (EPA) to have high mercury concentrations and who consume at least 6o z of locally caught fish per week to determine the feasibility of monitoring future trends among a population identified as highly exposed. Blood samples were collected at time of interview and analyzed for mercury. Participants (n=287) were enrolled from North Carolina, Maryland, and South Dakota. Participants reported eating an average of five servings of fish per week. The overall geometric mean for total mercury was 0.75 μg L(-1), with North Carolina having the highest mean level (2.02 μg L(-1)). Overall, 42% of the study population had levels greater than the US geometric mean 0.83 μg L(-1). The number of servings of fish consumed was not found to be associated with blood mercury levels. We were able to identify some persons with elevated mercury concentrations living in areas identified by EPA; however, identifying and monitoring a highly exposed population over time would be challenging. Published by Elsevier Ltd. JF - Chemosphere AU - Wolkin, Amy AU - Hunt, Danielle AU - Martin, Colleen AU - Caldwell, Kathleen L AU - McGeehin, Michael A AD - National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA. ajf9@cdc.gov Y1 - 2012/03// PY - 2012 DA - March 2012 SP - 967 EP - 971 VL - 86 IS - 9 KW - Water Pollutants, Chemical KW - 0 KW - Mercury KW - FXS1BY2PGL KW - Index Medicus KW - Animals KW - Age Factors KW - Aged, 80 and over KW - Humans KW - North Carolina KW - Adult KW - Aged KW - Middle Aged KW - Maryland KW - Adolescent KW - Male KW - Female KW - South Dakota KW - Environmental Monitoring KW - Mercury -- blood KW - Fishes KW - Food Contamination KW - Water Pollutants, Chemical -- blood UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/919649802?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemosphere&rft.atitle=Blood+mercury+levels+among+fish+consumers+residing+in+areas+with+high+environmental+burden.&rft.au=Wolkin%2C+Amy%3BHunt%2C+Danielle%3BMartin%2C+Colleen%3BCaldwell%2C+Kathleen+L%3BMcGeehin%2C+Michael+A&rft.aulast=Wolkin&rft.aufirst=Amy&rft.date=2012-03-01&rft.volume=86&rft.issue=9&rft.spage=967&rft.isbn=&rft.btitle=&rft.title=Chemosphere&rft.issn=1879-1298&rft_id=info:doi/10.1016%2Fj.chemosphere.2011.11.026 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-10-02 N1 - Date created - 2012-02-01 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.chemosphere.2011.11.026 ER - TY - JOUR T1 - Multilevel Measurement of Dimensions of Collaborative Functioning in a Network of Collaboratives that Promote Child and Family Well-Being AN - 1257881369; 16398940 AB - Evaluating collaboration between community partners presents a series of methodological challenges (Roussos and Fawcett in Annu Rev Public Health 21:369-402, 2000; Yin and Kaftarian 1997), one of which is selection of the appropriate level of analysis. When data are collected from multiple members of multiple settings, multilevel analysis techniques should be used. Multilevel confirmatory factor analysis (MCFA) is an analytic approach that incorporates the advantages of latent variable measurement modeling and multilevel modeling for nested data. This study utilizes MCFA on data obtained from an evaluation survey of collaborative functioning provided to members of 157 community collaboratives in Georgia. This study presents a well-fitting measurement model that includes five dimensions of collaborative functioning, and a structural component with individual- and collaborative-level covariates. Findings suggest that members' role and meeting attendance significantly predicted their assessment of collaboration at the individual level, and that tenure of collaborative leaders predicted the overall functioning of the collaborative at the collaborative level. Dimensionality of collaborative functioning and implications of potentially substantial measurement biases associated with selection of respondents are addressed. JF - American Journal of Community Psychology AU - Barile, John P AU - Darnell, Adam J AU - Erickson, Steve W AU - Weaver, Scott R AD - Department of Psychology, Georgia State University, Atlanta, GA, USA, jbarile@cdc.gov Y1 - 2012/03// PY - 2012 DA - Mar 2012 SP - 270 EP - 282 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 49 IS - 1-2 SN - 0091-0562, 0091-0562 KW - Health & Safety Science Abstracts KW - Public health KW - USA, Georgia KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1257881369?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Community+Psychology&rft.atitle=Multilevel+Measurement+of+Dimensions+of+Collaborative+Functioning+in+a+Network+of+Collaboratives+that+Promote+Child+and+Family+Well-Being&rft.au=Barile%2C+John+P%3BDarnell%2C+Adam+J%3BErickson%2C+Steve+W%3BWeaver%2C+Scott+R&rft.aulast=Barile&rft.aufirst=John&rft.date=2012-03-01&rft.volume=49&rft.issue=1-2&rft.spage=270&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Community+Psychology&rft.issn=00910562&rft_id=info:doi/10.1007%2Fs10464-011-9455-9 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-12-01 N1 - Last updated - 2013-01-11 N1 - SubjectsTermNotLitGenreText - Public health; USA, Georgia DO - http://dx.doi.org/10.1007/s10464-011-9455-9 ER - TY - JOUR T1 - Concurrent medical conditions and health care use and needs among children with learning and behavioral developmental disabilities, National Health Interview Survey, 2006-2010 AN - 1023093386; 201218054 AB - Studies document various associated health risks for children with developmental disabilities (DDs). Further study is needed by disability type. Using the 2006-2010 National Health Interview Surveys, we assessed the prevalence of numerous medical conditions (e.g. asthma, frequent diarrhea/colitis, seizures), health care use measures (e.g. seeing a medical specialist and >9 office visits in past year), health impact measures (e.g. needing help with personal care), and selected indicators of unmet health needs (e.g. unable to afford needed prescription medications) among a nationally representative sample of children ages 3-17 years, with and without DDs. Children in four mutually exclusive developmental disability groups: autism (N = 375), intellectual disability (ID) without autism (N = 238); attention-deficit/hyperactivity disorder (ADHD) without autism or ID (N = 2901); and learning disability (LD) or other developmental delay without ADHD, autism, or ID (N = 1955); were compared to children without DDs (N = 35,775) on each condition or health care measure of interest. Adjusted odds ratios (aORs) were calculated from weighted logistic regression models that accounted for the complex sample design. Prevalence estimates for most medical conditions examined were moderately to markedly higher for children in all four DD groups than children without DDs. Most differences were statistically significant after adjustment for child sex, age, race/ethnicity, and maternal education. Children in all DD groups also had significantly higher estimates for health care use, impact, and unmet needs measures than children without DDs. This study provides empirical evidence that children with DDs require increased pediatric and specialist services, both for their core functional deficits and concurrent medical conditions. [Copyright Elsevier B.V.] JF - Research in Developmental Disabilities AU - Schieve, Laura A AU - Gonzalez, Vanessa AU - Boulet, Sheree L AU - Visser, Susanna N AU - Rice, Catherine E AU - Braun, Kim Van Naarden AU - Boyle, Coleen A AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention Y1 - 2012/03// PY - 2012 DA - March 2012 SP - 467 EP - 476 PB - Elsevier Ltd, The Netherlands VL - 33 IS - 2 SN - 0891-4222, 0891-4222 KW - Developmental disabilities KW - Health services research KW - Chronic diseases KW - Epidemiology KW - Medical conditions KW - Health care KW - Health KW - Learning disabilities KW - Autistic children KW - Children KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1023093386?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Research+in+Developmental+Disabilities&rft.atitle=Concurrent+medical+conditions+and+health+care+use+and+needs+among+children+with+learning+and+behavioral+developmental+disabilities%2C+National+Health+Interview+Survey%2C+2006-2010&rft.au=Schieve%2C+Laura+A%3BGonzalez%2C+Vanessa%3BBoulet%2C+Sheree+L%3BVisser%2C+Susanna+N%3BRice%2C+Catherine+E%3BBraun%2C+Kim+Van+Naarden%3BBoyle%2C+Coleen+A&rft.aulast=Schieve&rft.aufirst=Laura&rft.date=2012-03-01&rft.volume=33&rft.issue=2&rft.spage=467&rft.isbn=&rft.btitle=&rft.title=Research+in+Developmental+Disabilities&rft.issn=08914222&rft_id=info:doi/10.1016%2Fj.ridd.2011.10.008 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2012-07-01 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Children; Autistic children; Medical conditions; Health; Health care; Learning disabilities DO - http://dx.doi.org/10.1016/j.ridd.2011.10.008 ER - TY - JOUR T1 - Mutations of rpoB gene in multidrug resistant Mycobacterium tuberculosis clinical isolates from Henan province AN - 1020855562; 16735934 AB - Aim: To analyze the characteristics of the mutations of rpoB genes in multidrug resistant Mycobacterium tuberculosis (MDR-TB) clinical isolates from Henan province. Methods: A total of 150 MDR-TB clinical strains were collected and the mutation patterns of rpoB full ORF was detected by PCR and sequencing with H37Rv as control. Results: 97.2% (140/144) isolates carried mutations in the full ORF of rpoB gene, and 96.5% (139/144) isolates carried mutations in RRDR.99% (139/140) isolates showed mutations both in the RRDR and outside the RRDR. The top 3 loci with high mutation frequency were rpoB531, rpoB526 and rpoB516. Discovered 15 mutation loci and 4 mutation types that had not been recorded previously. Among them, rpoB1284 probably was polymorphism locus and had nothing to do with rifampcin resistance. Conclusion: It is of high sensitivity to discover MDR-TB by detecting mutation loci within RRDR. JF - Zhengzhou Daxue Xuebao (Yixue Ban) - Journal of Zhengzhou University. Medical sciences AU - Zhao, Y AU - Yang, H AU - Ma, X AU - Shi, J AU - Li, H AU - Zhao, D AD - Institution of Tuberculosis Prevention and Control, Center for Disease Control and Prevention of Henan Province, Zhengzhou 450016, wbb558@hotmail.com Y1 - 2012/03// PY - 2012 DA - Mar 2012 SP - 166 EP - 169 VL - 47 IS - 2 SN - 1671-6825, 1671-6825 KW - Genetics Abstracts; Microbiology Abstracts B: Bacteriology KW - Clinical isolates KW - Multidrug resistance KW - Mutation KW - Open reading frames KW - Polymerase chain reaction KW - RpoB protein KW - Mycobacterium tuberculosis KW - J 02310:Genetics & Taxonomy KW - G 07770:Bacteria UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1020855562?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Zhengzhou+Daxue+Xuebao+%28Yixue+Ban%29+-+Journal+of+Zhengzhou+University.+Medical+sciences&rft.atitle=Mutations+of+rpoB+gene+in+multidrug+resistant+Mycobacterium+tuberculosis+clinical+isolates+from+Henan+province&rft.au=Zhao%2C+Y%3BYang%2C+H%3BMa%2C+X%3BShi%2C+J%3BLi%2C+H%3BZhao%2C+D&rft.aulast=Zhao&rft.aufirst=Y&rft.date=2012-03-01&rft.volume=47&rft.issue=2&rft.spage=166&rft.isbn=&rft.btitle=&rft.title=Zhengzhou+Daxue+Xuebao+%28Yixue+Ban%29+-+Journal+of+Zhengzhou+University.+Medical+sciences&rft.issn=16716825&rft_id=info:doi/10.3969%2Fj.issn.1671-6825.2012.02.009 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-06-01 N1 - Last updated - 2012-10-19 N1 - SubjectsTermNotLitGenreText - Clinical isolates; Polymerase chain reaction; Multidrug resistance; Mutation; Open reading frames; RpoB protein; Mycobacterium tuberculosis DO - http://dx.doi.org/10.3969/j.issn.1671-6825.2012.02.009 ER - TY - JOUR T1 - Use of parks or playgrounds: reported access to drinking water fountains among US adults, 2009 AN - 1008825586; 16422757 AB - Background As a first step to determining the public availability of drinking water, self-reported access to water fountains in parks and playgrounds was examined. Methods A cross-sectional analysis was conducted on a convenience sample of 4163 US adults (aged greater than or equal to 18 years) using the 2009 HealthStyles Survey. The outcome measure was reported access to water fountains in parks/playgrounds. Among those who reported using parks/playgrounds, multivariable logistic regression was used to examine the associations between sociodemographic variables and reported access to water fountains. Results About half (54.7%) of participants used parks/playgrounds. Among those, 55.0% reported access to water fountains. Factors significantly associated with reported access to water fountains were being male [odds ratio (OR) = 1.42; 95% confidence interval (CI) = 1.09, 1.85] and living in the Pacific region (versus East North Central region, OR = 2.56; 95% CI = 1.61, 4.06). Age, race/ethnicity, household income, marital status, education, smoking and physical activity were not significantly associated with reported access to water fountains. Conclusions Among 54.7% of adults using parks/playgrounds, reported access to water fountains was significantly differed by sex and region. This study provides information that can be considered when developing interventions to increase access to drinking water in public facilities. JF - Journal of Public Health AU - Park, Sohyun AU - Sherry, Bettylou AU - Wethington, Holly AU - Pan, Liping AD - Division of Nutrition, Physical Activity, and Obesity, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Mailstop K26, 4770 Buford Highway, NE, Atlanta, GA 30341, USA, spark3@cdc.gov Y1 - 2012/03// PY - 2012 DA - Mar 2012 SP - 65 EP - 72 PB - Oxford University Press, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 34 IS - 1 SN - 1741-3842, 1741-3842 KW - Environment Abstracts KW - marriage KW - USA, North Central Region KW - USA KW - Education KW - households KW - Recreation areas KW - income KW - intervention KW - IN, Pacific KW - Drinking water KW - physical activity KW - Ethnic groups KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1008825586?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Public+Health&rft.atitle=Use+of+parks+or+playgrounds%3A+reported+access+to+drinking+water+fountains+among+US+adults%2C+2009&rft.au=Park%2C+Sohyun%3BSherry%2C+Bettylou%3BWethington%2C+Holly%3BPan%2C+Liping&rft.aulast=Park&rft.aufirst=Sohyun&rft.date=2012-03-01&rft.volume=34&rft.issue=1&rft.spage=65&rft.isbn=&rft.btitle=&rft.title=Journal+of+Public+Health&rft.issn=17413842&rft_id=info:doi/10.1093%2Fpubmed%2Ffdr047 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-01 N1 - Last updated - 2012-05-07 N1 - SubjectsTermNotLitGenreText - households; Education; Recreation areas; intervention; income; physical activity; marriage; Drinking water; Ethnic groups; USA; IN, Pacific; USA, North Central Region DO - http://dx.doi.org/10.1093/pubmed/fdr047 ER - TY - JOUR T1 - Comparison of digital with film radiographs for the classification of pneumoconiotic pleural abnormalities. AN - 913718170; 22098943 AB - Analog film radiographs are typically used to classify pneumoconiosis to allow comparison with standard film radiographs. The aim of this study was to determine if digital radiography is comparable to film for the purpose of classifying pneumoconiotic pleural abnormalities. Subjects were 200 asbestos-exposed patients, from whom digital and film chest radiographs were obtained along with chest high-resolution computed tomographic scans. Using a crossover design, radiographs were independently read on two occasions by seven readers, using conventional International Labour Organization standards for film and digitized standards for digital. High-resolution computed tomographic scans were read independently by three readers. Areas under the receiver-operating characteristic curves were calculated using high-resolution computed tomographic ratings as the gold standard for disease status. Mixed linear models were fit to estimate the effects of order of presentation, occasion, and modality, treating the seven readers as a random effect. Comparing digital and film radiography for each reader and occasion, crude agreement and agreement beyond chance (κ) were also calculated. The linear models showed no statistically significant sequence effect for order of presentation (P = .73) or occasion (P = .28). Most important, the difference between modalities was not statistically significant (digital vs film, P = .54). The mean area under the curve for film was 0.736 and increased slightly to 0.741 for digital. Mean crude agreement for the presence of pleural abnormalities consistent with pneumoconiosis across all readers and occasions was 78.3%, while the mean κ value was 0.49. These results indicate that digital radiography is not statistically different from analog film for the purpose of classifying pneumoconiotic pleural abnormalities, when appropriate standards are used. Published by Elsevier Inc. JF - Academic radiology AU - Larson, Theodore C AU - Holiday, David B AU - Antao, Vinicius C AU - Thomas, Jerry AU - Pinheiro, Germania AU - Kapil, Vikas AU - Franzblau, Alfred AD - Division of Health Studies, Agency for Toxic Substances and Disease Registry, Atlanta, GA 30341, USA. tlarson@cdc.gov Y1 - 2012/02// PY - 2012 DA - February 2012 SP - 131 EP - 140 VL - 19 IS - 2 KW - Index Medicus KW - Reproducibility of Results KW - ROC Curve KW - Area Under Curve KW - Humans KW - Linear Models KW - Cross-Over Studies KW - Middle Aged KW - Male KW - Female KW - Tomography, X-Ray Computed -- methods KW - Pneumoconiosis -- diagnostic imaging KW - Radiography, Thoracic -- methods KW - X-Ray Film KW - Radiographic Image Enhancement -- methods KW - Pneumoconiosis -- classification KW - Radiography, Thoracic -- classification KW - Pleural Diseases -- diagnostic imaging UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/913718170?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Academic+radiology&rft.atitle=Comparison+of+digital+with+film+radiographs+for+the+classification+of+pneumoconiotic+pleural+abnormalities.&rft.au=Larson%2C+Theodore+C%3BHoliday%2C+David+B%3BAntao%2C+Vinicius+C%3BThomas%2C+Jerry%3BPinheiro%2C+Germania%3BKapil%2C+Vikas%3BFranzblau%2C+Alfred&rft.aulast=Larson&rft.aufirst=Theodore&rft.date=2012-02-01&rft.volume=19&rft.issue=2&rft.spage=131&rft.isbn=&rft.btitle=&rft.title=Academic+radiology&rft.issn=1878-4046&rft_id=info:doi/10.1016%2Fj.acra.2011.10.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-04-27 N1 - Date created - 2012-01-03 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.acra.2011.10.002 ER - TY - JOUR T1 - Characteristics, Services, and Infection Control Practices of New York City Assisted Living Facilities, 2010 AN - 1257881692; 16384861 AB - To describe New York City (NYC) assisted living facility (ALF) characteristics, services offered, and infection control practices and to identify infection control barriers and unmet needs. ALFs licensed or applying to be licensed in NYC. Seventy ALFs; 70 of 77 eligible facilities participated (91% participation rate). Telephone interview questions assessed ALF characteristics, services offered, and infection control practices, including glucometry practices. ALFs provided a broad range of services, such as vaccination (90%), assistance with taking medication (75%), bathing and showering (33%), and blood glucose monitoring (90%). Ninety percent of the facilities had nurses on site (directly employed or through a contract agency). Five facilities reported that residents sometimes shared glucometers, and one reported that fingerstick devices were sometimes shared. The majority of facilities wanted educational materials for staff (83%) and residents (77%) on topics including influenza, respiratory illness, norovirus, standard precautions, and general infection control. ALFs had a range of sick leave policies and infection control training requirements. Eighty-nine percent of the facilities reported having designated staff responsible for infection control, although 50% had nonclinical job titles. NYC ALFs were varied in terms of nursing services offered, characteristics, and residents' needs; therefore, public health agencies may need to be flexible in their assistance. Public health agencies should consider strengthening relationships with ALFs to identify unmet needs and gaps in services.Original Abstract: Cross-sectional. JF - Journal of the American Geriatrics Society AU - Stachel, Anna G AU - Bornschlegel, Katherine AU - Balter, Sharon AD - Center for Disease Control and Prevention. Council of State and Territorial Epidemiologists Y1 - 2012/02// PY - 2012 DA - Feb 2012 SP - 284 EP - 289 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 60 IS - 2 SN - 0002-8614, 0002-8614 KW - Health & Safety Science Abstracts KW - Influenza KW - USA, New York, New York City KW - Contracts KW - Training KW - Nursing KW - Glucose KW - Norovirus KW - Infection KW - Medical personnel KW - Public health KW - Urban areas KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1257881692?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+American+Geriatrics+Society&rft.atitle=Characteristics%2C+Services%2C+and+Infection+Control+Practices+of+New+York+City+Assisted+Living+Facilities%2C+2010&rft.au=Stachel%2C+Anna+G%3BBornschlegel%2C+Katherine%3BBalter%2C+Sharon&rft.aulast=Stachel&rft.aufirst=Anna&rft.date=2012-02-01&rft.volume=60&rft.issue=2&rft.spage=284&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+American+Geriatrics+Society&rft.issn=00028614&rft_id=info:doi/10.1111%2Fj.1532-5415.2011.03817.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-12-01 N1 - Number of references - 17 N1 - Last updated - 2013-06-28 N1 - SubjectsTermNotLitGenreText - Influenza; Contracts; Training; Nursing; Glucose; Infection; Medical personnel; Urban areas; Public health; Norovirus; USA, New York, New York City DO - http://dx.doi.org/10.1111/j.1532-5415.2011.03817.x ER - TY - JOUR T1 - The economic burden of child maltreatment in the United States and implications for prevention AN - 1023031496; 201204716 AB - To present new estimates of the average lifetime costs per child maltreatment victim and aggregate lifetime costs for all new child maltreatment cases incurred in 2008 using an incidence-based approach. This study used the best available secondary data to develop cost per case estimates. For each cost category, the paper used attributable costs whenever possible. For those categories that attributable cost data were not available, costs were estimated as the product of incremental effect of child maltreatment on a specific outcome multiplied by the estimated cost associated with that outcome. The estimate of the aggregate lifetime cost of child maltreatment in 2008 was obtained by multiplying per-victim lifetime cost estimates by the estimated cases of new child maltreatment in 2008. The estimated average lifetime cost per victim of nonfatal child maltreatment is $210,012 in 2010 dollars, including $32,648 in childhood health care costs; $10,530 in adult medical costs; $144,360 in productivity losses; $7,728 in child welfare costs; $6,747 in criminal justice costs; and $7,999 in special education costs. The estimated average lifetime cost per death is $1,272,900, including $14,100 in medical costs and $1,258,800 in productivity losses. The total lifetime economic burden resulting from new cases of fatal and nonfatal child maltreatment in the United States in 2008 is approximately $124 billion. In sensitivity analysis, the total burden is estimated to be as large as $585 billion. Compared with other health problems, the burden of child maltreatment is substantial, indicating the importance of prevention efforts to address the high prevalence of child maltreatment. [Copyright Elsevier Ltd.] JF - Child Abuse & Neglect AU - Fang, Xiangming AU - Brown, Derek S AU - Florence, Curtis S AU - Mercy, James A AD - National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA, USA Y1 - 2012/02// PY - 2012 DA - February 2012 SP - 156 EP - 165 PB - Elsevier Science, Amsterdam The Netherlands VL - 36 IS - 2 SN - 0145-2134, 0145-2134 KW - Child maltreatment Economic burden Lifelong consequences KW - Prevention KW - Health Problems KW - Victims KW - Child Neglect KW - United States of America KW - Medicine KW - Criminal Justice KW - Productivity KW - Health Care Costs KW - article KW - 6143: child & family welfare UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1023031496?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocialservices&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Child+Abuse+%26+Neglect&rft.atitle=The+economic+burden+of+child+maltreatment+in+the+United+States+and+implications+for+prevention&rft.au=Fang%2C+Xiangming%3BBrown%2C+Derek+S%3BFlorence%2C+Curtis+S%3BMercy%2C+James+A&rft.aulast=Fang&rft.aufirst=Xiangming&rft.date=2012-02-01&rft.volume=36&rft.issue=2&rft.spage=156&rft.isbn=&rft.btitle=&rft.title=Child+Abuse+%26+Neglect&rft.issn=01452134&rft_id=info:doi/10.1016%2Fj.chiabu.2011.10.006 LA - English DB - Social Services Abstracts N1 - Date revised - 2012-07-01 N1 - Last updated - 2016-09-28 N1 - CODEN - CABND3 N1 - SubjectsTermNotLitGenreText - Child Neglect; Health Care Costs; Productivity; Prevention; Victims; Medicine; United States of America; Criminal Justice; Health Problems DO - http://dx.doi.org/10.1016/j.chiabu.2011.10.006 ER - TY - JOUR T1 - Retaining clients in an outcome monitoring evaluation study: HIV prevention efforts in community settings AN - 1023027339; 201203993 AB - The Centers for Disease Control and Prevention (CDC), Division of HIV/AIDS Prevention (DHAP) conducted outcome monitoring studies on evidence-based interventions (EBIs) provided by CDC-funded community-based organizations (CBOs). Critical to the success of outcome monitoring was the ability of CBOs to recruit and retain clients in evaluation studies. Two EBIs, Video Opportunities for Innovative Condom Education and Safer Sex (VOICES/VOCES) and Healthy Relationships, were evaluated using repeated measure studies, which require robust follow-up retention rates to increase the validity and usefulness of the findings. The retention rates were high for both VOICES/VOCES CBOs (95.8% at 30 days and 91.1% at 120 days), and Healthy Relationships CBOs (89.5% at 90 days and 83.5% at 180 days). This paper presents an overview of the retention of clients, challenges to follow-up, and strategies developed by CBOs to achieve high retention rates. These strategies and rates are discussed within the context of the CBOs' target populations and communities. [Copyright Elsevier Ltd.] JF - Evaluation and Program Planning AU - Smith, Bryce D AU - Kalayil, Elizabeth J AU - Patel-Larson, Alpa AU - Chen, Brenda AU - Vaughan, Marla AD - Program Evaluation Branch, Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Mail Stop E-37. 1600 Clifton Road NE, Atlanta, GA 30333, USA Tel.: +1 404 639 6277: Fax: +1 718 8595 bsmith6@cdc.gov Y1 - 2012/02// PY - 2012 DA - February 2012 SP - 16 EP - 24 PB - Elsevier Ltd., Amsterdam The Netherlands VL - 35 IS - 1 SN - 0149-7189, 0149-7189 KW - HIV/AIDS prevention, Evidence-based interventions, Evaluation, Outcome monitoring, Retention strategies KW - Condoms KW - Prevention KW - Attrition KW - Acquired Immune Deficiency Syndrome KW - Sex Education KW - Intervention KW - Community Services KW - Community Organizations KW - Health Care Services KW - article KW - 6126: acquired immune deficiency syndrome (AIDS) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1023027339?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocialservices&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Evaluation+and+Program+Planning&rft.atitle=Retaining+clients+in+an+outcome+monitoring+evaluation+study%3A+HIV+prevention+efforts+in+community+settings&rft.au=Smith%2C+Bryce+D%3BKalayil%2C+Elizabeth+J%3BPatel-Larson%2C+Alpa%3BChen%2C+Brenda%3BVaughan%2C+Marla&rft.aulast=Smith&rft.aufirst=Bryce&rft.date=2012-02-01&rft.volume=35&rft.issue=1&rft.spage=16&rft.isbn=&rft.btitle=&rft.title=Evaluation+and+Program+Planning&rft.issn=01497189&rft_id=info:doi/10.1016%2Fj.evalprogplan.2011.06.002 LA - English DB - Social Services Abstracts N1 - Date revised - 2012-07-01 N1 - Last updated - 2016-09-28 N1 - CODEN - EPPLDO N1 - SubjectsTermNotLitGenreText - Attrition; Acquired Immune Deficiency Syndrome; Prevention; Community Services; Condoms; Health Care Services; Community Organizations; Intervention; Sex Education DO - http://dx.doi.org/10.1016/j.evalprogplan.2011.06.002 ER - TY - JOUR T1 - The Good Enough Home? Home Environment and Outcomes of Young Maltreated Children AN - 1008848143; 16381033 AB - Background: Mixed results in the literature related to type of permanent placement and developmental outcomes of maltreated children suggest differences in postmaltreatment placement environments may be an important mechanism to consider. Objective: The goal of this study was to identify how home environment variables mediate risk in maltreated children in different types of placements. Methods: Participants included 71 maltreated and 70 non-maltreated (mean age = 7.14). Child outcomes were caregiver report of behavior problems (Child Behavior Checklist, CBCL) and cognitive assessment (Peabody Picture Vocabulary Test, PPVT, and Kaufman Brief Intelligence Test, KBIT). The home environment was examined using the Home Observation for Measurement of the Environment (HOME). Results: The maltreated and non-maltreated groups differed significantly on cognitive scores, F(6, 268) = 3.05, p < .01, behavior problems, F(18, 258) = 2.64, p < .001, and their home environments, F(14, 264) = 6.01, p < .001. Partial F tests predicting cognitive scores by group after controlling for HOME academic resources revealed mediation of cognitive scores for the bio-kin group only and mediation of CBCL Withdrawal, Social Problems, and Attention Problems by HOME emotional resources within the bio-kin group only. After controlling for SES in meditational analyses, within group differences were only found for the bio-kin group and Attention problems. Conclusions: Results suggest that maltreated children returned to biological parents or placed with relatives may have greater need for continued parenting support and academic resources; enhancing home environments so that they are both stimulating and cohesive is necessary. JF - Child and Youth Care Forum AU - Robinson, Lara R AU - Boris, Neil W AU - Heller, Sherryl Scott AU - Rice, Janet AU - Zeanah, Charles H AU - Clark, Cinda AU - Hawkins, Shantice AD - Department of Psychology, Pennsylvania State University, University Park, PA, USA, lpr0@cdc.gov Y1 - 2012/02// PY - 2012 DA - Feb 2012 SP - 73 EP - 88 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 41 IS - 1 SN - 1053-1890, 1053-1890 KW - Environment Abstracts KW - Age KW - Children KW - intelligence KW - social conditions KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1008848143?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Child+and+Youth+Care+Forum&rft.atitle=The+Good+Enough+Home%3F+Home+Environment+and+Outcomes+of+Young+Maltreated+Children&rft.au=Robinson%2C+Lara+R%3BBoris%2C+Neil+W%3BHeller%2C+Sherryl+Scott%3BRice%2C+Janet%3BZeanah%2C+Charles+H%3BClark%2C+Cinda%3BHawkins%2C+Shantice&rft.aulast=Robinson&rft.aufirst=Lara&rft.date=2012-02-01&rft.volume=41&rft.issue=1&rft.spage=73&rft.isbn=&rft.btitle=&rft.title=Child+and+Youth+Care+Forum&rft.issn=10531890&rft_id=info:doi/10.1007%2Fs10566-011-9157-3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-01 N1 - Last updated - 2012-05-18 N1 - SubjectsTermNotLitGenreText - Age; social conditions; Children; intelligence DO - http://dx.doi.org/10.1007/s10566-011-9157-3 ER - TY - JOUR T1 - Vaccination and risk of type 1 diabetes mellitus in active component U.S. Military, 2002-2008 AN - 920802276; 16262566 AB - Aims/hypothesis: To evaluate whether vaccination increases the risk of type 1 diabetes mellitus in active component U.S. military personnel. Methods: We conducted a retrospective cohort study among active component U.S. military personnel age 17-35 years. Individuals with first time diagnoses of type 1 diabetes between January 1, 2002 and December 31, 2008 were identified using International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes. We used Poisson regression to estimate risk ratios between individual vaccine exposures and type 1 diabetes. Secondary analyses were performed controlling for receipt of multiple vaccines and available demographic variables. Results: Our study population consisted of 2,385,102 individuals followed for approximately 7,644,098 person-years of service. This included 1074 incident type 1 diabetes cases. We observed no significant increased risk of type 1 diabetes after vaccination with anthrax vaccine adsorbed (AVA) [RR = 1.00; 95% CI (0.85, 1.17)], smallpox vaccine [RR = 0.84; 95% (CI 0.70, 1.01)], typhoid vaccine [RR = 1.03; 95% CI (0.87, 1.22)], hepatitis B vaccine [RR = 0.83; 95% CI (0.72, 0.95)], measles mumps rubella vaccine (MMR) [RR = 0.71, 95% CI (0.61, 0.83)], or yellow fever vaccine [RR = 0.70; 95% CI (0.59, 0.82)]. Conclusions: We did not find an increased risk of diagnosed type 1 diabetes and any of the study vaccines. We recommend that follow-up studies using medical record review to confirm case status should be considered to corroborate these findings. JF - Vaccine AU - Duderstadt, Susan K AU - Rose, Charles E AU - Real, Theresa M AU - Sabatier, Jennifer F AU - Stewart, Brock AU - Ma, Guihua AU - Yerubandi, Uma D AU - Eick, Angelia A AU - Tokars, Jerome I AU - McNeil, Michael M AD - Immunization Safety Office, Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, United States, mmm2@cdc.gov Y1 - 2012/01/17/ PY - 2012 DA - 2012 Jan 17 SP - 813 EP - 819 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 30 IS - 4 SN - 0264-410X, 0264-410X KW - Risk Abstracts; Health & Safety Science Abstracts; Immunology Abstracts KW - Age KW - Measles KW - Rubella KW - Demography KW - Classification KW - Yellow fever KW - Hepatitis B KW - Anthrax KW - Military KW - medical records KW - Population studies KW - Diabetes mellitus KW - Smallpox KW - USA KW - Secondary analysis KW - Reviews KW - Vaccines KW - Mumps KW - Military personnel KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health KW - F 06930:Autoimmunity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/920802276?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Vaccination+and+risk+of+type+1+diabetes+mellitus+in+active+component+U.S.+Military%2C+2002-2008&rft.au=Duderstadt%2C+Susan+K%3BRose%2C+Charles+E%3BReal%2C+Theresa+M%3BSabatier%2C+Jennifer+F%3BStewart%2C+Brock%3BMa%2C+Guihua%3BYerubandi%2C+Uma+D%3BEick%2C+Angelia+A%3BTokars%2C+Jerome+I%3BMcNeil%2C+Michael+M&rft.aulast=Duderstadt&rft.aufirst=Susan&rft.date=2012-01-17&rft.volume=30&rft.issue=4&rft.spage=813&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/10.1016%2Fj.vaccine.2011.10.087 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-02-01 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - Age; medical records; Measles; Population studies; Rubella; Smallpox; Diabetes mellitus; Demography; Classification; Yellow fever; Hepatitis B; Anthrax; Vaccines; Military personnel; Mumps; Secondary analysis; Reviews; Military; USA DO - http://dx.doi.org/10.1016/j.vaccine.2011.10.087 ER - TY - CPAPER T1 - Clinical ICP-MS I T2 - 2012 European Winter Conference on Plasma Spectrochemistry AN - 1313056768; 6107915 JF - 2012 European Winter Conference on Plasma Spectrochemistry AU - Jones, Robert AU - Caldwell, Kathleen AU - Jarrett, Jeff AU - Verdon, Carl Y1 - 2012/01/09/ PY - 2012 DA - 2012 Jan 09 KW - Plasma KW - Spectrochemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313056768?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2012+European+Winter+Conference+on+Plasma+Spectrochemistry&rft.atitle=Clinical+ICP-MS+I&rft.au=Jones%2C+Robert%3BCaldwell%2C+Kathleen%3BJarrett%2C+Jeff%3BVerdon%2C+Carl&rft.aulast=Jones&rft.aufirst=Robert&rft.date=2012-01-09&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2012+European+Winter+Conference+on+Plasma+Spectrochemistry&rft.issn=&rft_id=info:doi/ L2 - http://icpinformation.org/uploads/2012_Winter_Conference.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Sample Preparation Problem Solving for Atomic Mass Spectrometry T2 - 2012 European Winter Conference on Plasma Spectrochemistry AN - 1312980352; 6107959 JF - 2012 European Winter Conference on Plasma Spectrochemistry AU - Pappas, R Y1 - 2012/01/09/ PY - 2012 DA - 2012 Jan 09 KW - Mass spectroscopy KW - Problem solving UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312980352?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2012+European+Winter+Conference+on+Plasma+Spectrochemistry&rft.atitle=Sample+Preparation+Problem+Solving+for+Atomic+Mass+Spectrometry&rft.au=Pappas%2C+R&rft.aulast=Pappas&rft.aufirst=R&rft.date=2012-01-09&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2012+European+Winter+Conference+on+Plasma+Spectrochemistry&rft.issn=&rft_id=info:doi/ L2 - http://icpinformation.org/uploads/2012_Winter_Conference.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - JOUR T1 - What Do We Need to Know about Disease Ecology to Prevent Lyme Disease in the Northeastern United States? AN - 954640622; 16388417 AB - Lyme disease is the most commonly reported vector-borne disease in the United States, with the majority of cases occurring in the Northeast. It has now been three decades since the etiological agent of the disease in North America, the spirochete Borrelia burgdorferi, and its primary North American vectors, the ticks Ixodes scapularis Say and I. pacificus Cooley & Kohls, were identified. Great strides have been made in our understanding of the ecology of the vectors and disease agent, and this knowledge has been used to design a wide range of prevention and control strategies. However, despite these advances, the number of Lyme disease cases have steadily increased. In this article, we assess potential reasons for the continued lack of success in prevention and control of Lyme disease in the northeastern United States, and identify conceptual areas where additional knowledge could be used to improve Lyme disease prevention and control strategies. Some of these areas include: 1) identifying critical host infestation rates required to maintain enzootic transmission of B. burgdorferi, 2) understanding how habitat diversity and forest fragmentation impacts acarological risk of exposure to B. burgdorferi and the ability of interventions to reduce risk, 3) quantifying the epidemiological outcomes of interventions focusing on ticks or vertebrate reservoirs, and 4) refining knowledge of how human behavior influences Lyme disease risk and identifying barriers to the adoption of personal protective measures and environmental tick management. JF - Journal of Medical Entomology AU - Eisen, Rebecca J AU - Piesman, Joseph AU - Zielinski-Gutierrez, Emily AU - Eisen, Lars AD - Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, 3150 Rampart Road, Fort Collins, CO 80522., dyn2@cdc.gov Y1 - 2012/01// PY - 2012 DA - Jan 2012 SP - 11 EP - 22 PB - Entomological Society of America, 9301 Annapolis Rd. Lanham MD 20706 United States VL - 49 IS - 1 SN - 0022-2585, 0022-2585 KW - Microbiology Abstracts B: Bacteriology; Entomology Abstracts KW - Adoption KW - Disease transmission KW - Forests KW - Habitat KW - Habitat fragmentation KW - Infestation KW - Lyme disease KW - Spirochetes KW - Vector-borne diseases KW - Vectors KW - Borrelia burgdorferi KW - Ixodidae KW - Ixodes scapularis KW - Z 05340:Ecology and Behavior KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/954640622?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Medical+Entomology&rft.atitle=What+Do+We+Need+to+Know+about+Disease+Ecology+to+Prevent+Lyme+Disease+in+the+Northeastern+United+States%3F&rft.au=Eisen%2C+Rebecca+J%3BPiesman%2C+Joseph%3BZielinski-Gutierrez%2C+Emily%3BEisen%2C+Lars&rft.aulast=Eisen&rft.aufirst=Rebecca&rft.date=2012-01-01&rft.volume=49&rft.issue=1&rft.spage=11&rft.isbn=&rft.btitle=&rft.title=Journal+of+Medical+Entomology&rft.issn=00222585&rft_id=info:doi/10.1603%2FME11138 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Number of references - 113 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - Spirochetes; Infestation; Vector-borne diseases; Forests; Vectors; Adoption; Habitat; Habitat fragmentation; Disease transmission; Lyme disease; Borrelia burgdorferi; Ixodidae; Ixodes scapularis DO - http://dx.doi.org/10.1603/ME11138 ER - TY - JOUR T1 - Smokeless and Flavored Tobacco Products in the U.S.: 2009 Styles Survey Results AN - 925740184; 201205386 AB - A number of noncigarette tobacco products, including some novel products, recently have been marketed by the tobacco industry, which raises concerns from tobacco control authorities. Purpose: This study aimed to assess current popularity of several noncigarette tobacco products in the U.S. Methods: In 2009, a total of 10,587 adults completed a consumer mail-in survey (ConsumerStyles). Based on survey results, the weighted percentages of adults who heard and tried snus, dissolvable tobacco products, flavored little cigars, and flavored cigarettes were computed in 2010. A subset of this sample (n=4556) completed the HealthStyles survey, which included items about health perceptions of these products and use in the past 30 days. Results: The percentage of U.S. adults in the sample who were aware of these products ranged from 10.4% (dissolvable tobacco) to 44.6% (flavored little cigars). One third of adults who had heard of flavored little cigars tried them and 10.1% had used them in the past 30 days; among those who had heard of them, 27.4% tried flavored cigarettes and 12.6% tried snus. In general, young adults, men, and smokers were most likely to have heard of each product. At least one third of adults were uncertain if these products were as harmful as cigarettes (range=37.3% [snus] to 50.3% [dissolvable tobacco]). Conclusions: The awareness of these tobacco products in this sample varied. Groups with a higher prevalence of smoking and tobacco use (e.g., men, people with low levels of education) may be a target audience for marketing and promotions. As availability of products change, continued surveillance is warranted in the U.S. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Regan, Annette K AU - Dube, Shanta R AU - Arrazola, Rene AD - Office on Smoking and Health, National Center for Chronic Disease Prevention and Health Promotion, CDC, Atlanta, Georgia Y1 - 2012///0, PY - 2012 DA - 0, 2012 SP - 29 EP - 36 PB - Elsevier Science, New York NY VL - 42 IS - 1 SN - 0749-3797, 0749-3797 KW - Smoking KW - Men KW - Tobacco products KW - Cigars KW - Surveillance KW - Prevalence KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/925740184?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Smokeless+and+Flavored+Tobacco+Products+in+the+U.S.%3A+2009+Styles+Survey+Results&rft.au=Regan%2C+Annette+K%3BDube%2C+Shanta+R%3BArrazola%2C+Rene&rft.aulast=Regan&rft.aufirst=Annette&rft.date=2012-01-01&rft.volume=42&rft.issue=1&rft.spage=29&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2011.08.019 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2012-03-01 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Smoking; Tobacco products; Cigars; Men; Prevalence; Surveillance DO - http://dx.doi.org/10.1016/j.amepre.2011.08.019 ER - TY - JOUR T1 - A History of Being Prescribed Controlled Substances and Risk of Drug Overdose Death AN - 920800193; 16240016 AB - Objective. The abuse of prescription drugs has increased dramatically since 1990. Persons who overdose on such drugs frequently consume large doses and visit multiple providers. The risk of fatal overdose for different patterns of use of opioid analgesics and sedative/hypnotics has not been fully quantified. Design. Matched case-control study. Cases were 300 persons who died of unintentional drug overdoses in New Mexico during 2006-2008, and controls were 5,993 patients identified through the state prescription monitoring program with matching 6-month exposure periods. Outcome Measures. Death from drug overdose or death from opioid overdose. Exposures were demographic variables and characteristics of prescription history. Crude and adjusted odds ratios (AOR) were calculated. Results. Increased risk was associated with male sex (AOR 2.4, 95% confidence interval [CI] 1.8-3.1), one or more sedative/hypnotic prescriptions (AOR 3.0, CI 2.2-4.2), greater age (AOR 1.3, CI 1.2-1.4 for each 10-year increment), number of prescriptions (AOR 1.1, CI 1.1-1.1 for each additional prescription), and a prescription for buprenorphine (AOR 9.5, CI 3.0-30.0), fentanyl (AOR 3.5, CI 1.7-7.0), hydromorphone (AOR 3.3, CI 1.4-7.5), methadone (AOR 4.9, CI 2.5-9.6), or oxycodone (AOR 1.9, CI 1.4-2.6). Patients receiving a daily average of >40 morphine milligram equivalents had an OR of 12.2 (CI 9.2-16.0). Conclusions. Patients being prescribed opioid analgesics frequently or at high dosage face a substantial overdose risk. Prescription monitoring programs might be the best way for prescribers to know their patients' prescription histories and accurately assess overdose risk. JF - Pain Medicine AU - Paulozzi, Leonard J AU - Kilbourne, Edwin M AU - Shah, Nina G AU - Nolte, Kurt B AU - Desai, Hema A AU - Landen, Michael G AU - Harvey, William AU - Loring, Larry D AD - Division of Unintentional Injury Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia Y1 - 2012/01// PY - 2012 DA - Jan 2012 SP - 87 EP - 95 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 13 IS - 1 SN - 1526-2375, 1526-2375 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Age KW - Demography KW - Drugs KW - Historical account KW - Mortality KW - Overdose KW - Pain KW - demography KW - overdose KW - pain KW - USA, New Mexico KW - R2 23060:Medical and environmental health KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/920800193?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Pain+Medicine&rft.atitle=A+History+of+Being+Prescribed+Controlled+Substances+and+Risk+of+Drug+Overdose+Death&rft.au=Paulozzi%2C+Leonard+J%3BKilbourne%2C+Edwin+M%3BShah%2C+Nina+G%3BNolte%2C+Kurt+B%3BDesai%2C+Hema+A%3BLanden%2C+Michael+G%3BHarvey%2C+William%3BLoring%2C+Larry+D&rft.aulast=Paulozzi&rft.aufirst=Leonard&rft.date=2012-01-01&rft.volume=13&rft.issue=1&rft.spage=87&rft.isbn=&rft.btitle=&rft.title=Pain+Medicine&rft.issn=15262375&rft_id=info:doi/10.1111%2Fj.1526-4637.2011.01260.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-02-01 N1 - Document feature - figure 3 N1 - Last updated - 2012-10-19 N1 - SubjectsTermNotLitGenreText - Demography; demography; Mortality; Historical account; Overdose; Age; pain; overdose; Pain; Drugs; USA, New Mexico DO - http://dx.doi.org/10.1111/j.1526-4637.2011.01260.x ER - TY - JOUR T1 - Mixing in age-structured population models of infectious diseases AN - 915494892; 16148826 AB - Infectious diseases are controlled by reducing pathogen replication within or transmission between hosts. Models can reliably evaluate alternative strategies for curtailing transmission, but only if interpersonal mixing is represented realistically. Compartmental modelers commonly use convex combinations of contacts within and among groups of similarly aged individuals, respectively termed preferential and proportionate mixing. Recently published face-to-face conversation and time-use studies suggest that parents and children and co-workers also mix preferentially. As indirect effects arise from the off-diagonal elements of mixing matrices, these observations are exceedingly important. Accordingly, we refined the formula published by Jacquez et al. to account for these newly-observed patterns and estimated age-specific fractions of contacts with each preferred group. As the ages of contemporaries need not be identical nor those of parents and children to differ by exactly the generation time, we also estimated the variances of the Gaussian distributions with which we replaced the Kronecker delta commonly used in theoretical studies. Our formulae reproduce observed patterns and can be used, given contacts, to estimate probabilities of infection on contact, infection rates, and reproduction numbers. As examples, we illustrate these calculations for influenza based on "attack rates" from a prospective household study during the 1957 pandemic and for varicella based on cumulative incidence estimated from a cross-sectional serological survey conducted from 1988-94, together with contact rates from the several face-to-face conversation and time-use studies. Susceptibility to infection on contact generally declines with age, but may be elevated among adolescents and adults with young children. JF - Mathematical Biosciences AU - Glasser, John AU - Feng, Zhilan AU - Moylan, Andrew AU - Del Valle, Sara AU - Castillo-Chavez, Carlos AD - Centers for Disease Control and Prevention, Atlanta, GA, USA, jglasser@cdc.gov Y1 - 2012/01// PY - 2012 DA - Jan 2012 SP - 1 EP - 7 PB - Elsevier B.V., Box 882 New York NY 10159 United States VL - 235 IS - 1 SN - 0025-5564, 0025-5564 KW - Ecology Abstracts; Biotechnology and Bioengineering Abstracts KW - Adolescence KW - Infection KW - W 30910:Imaging KW - D:04030 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/915494892?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Mathematical+Biosciences&rft.atitle=Mixing+in+age-structured+population+models+of+infectious+diseases&rft.au=Glasser%2C+John%3BFeng%2C+Zhilan%3BMoylan%2C+Andrew%3BDel+Valle%2C+Sara%3BCastillo-Chavez%2C+Carlos&rft.aulast=Glasser&rft.aufirst=John&rft.date=2012-01-01&rft.volume=235&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Mathematical+Biosciences&rft.issn=00255564&rft_id=info:doi/10.1016%2Fj.mbs.2011.10.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-01-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Infection DO - http://dx.doi.org/10.1016/j.mbs.2011.10.001 ER - TY - JOUR T1 - Human Papillomavirus Vaccine and Sexual Behavior Among Adolescent and Young Women AN - 915483093; 16148909 AB - Vaccines to prevent certain types of human papillomavirus (HPV) and associated cancers are recommended for routine use among young women. Nationally representative reports of vaccine uptake have not explored the relationship between HPV vaccine initiation and various sexual behaviors. Purpose: Explore sexual behavior and demographic correlates of HPV vaccine initiation from a nationally representative survey of adolescent and young adult women. Methods: In 2007-2008, a total of 1243 girls/women aged 15-24 years responded to questions about receiving HPV vaccine in the National Survey of Family Growth (NSFG). In 2010, demographic and sexual behavior correlates were evaluated in bivariate and multivariate analyses by age. Results: HPV vaccine initiation was higher among those aged 15-19 years than those aged 20-24 years (30.3% vs 15.9%, p19 years. No association was found between HPV vaccination and risky sexual behavior. JF - American Journal of Preventive Medicine AU - Liddon, Nicole C AU - Leichliter, Jami S AU - Markowitz, Lauri E AD - Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, CDC, Atlanta, Georgia, nliddon@cdc.gov Y1 - 2012/01// PY - 2012 DA - Jan 2012 SP - 44 EP - 52 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 42 IS - 1 SN - 0749-3797, 0749-3797 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts; Risk Abstracts KW - demography KW - sexual behavior KW - vaccines KW - Age KW - Sexual behavior KW - Demography KW - Condoms KW - Multivariate analysis KW - Adolescents KW - Ethnic groups KW - Races KW - Sex KW - Adolescence KW - Race differences KW - Insurance KW - Cancer KW - Vaccines KW - wear KW - Human papillomavirus KW - R2 23060:Medical and environmental health KW - V 22400:Human Diseases KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/915483093?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Human+Papillomavirus+Vaccine+and+Sexual+Behavior+Among+Adolescent+and+Young+Women&rft.au=Liddon%2C+Nicole+C%3BLeichliter%2C+Jami+S%3BMarkowitz%2C+Lauri+E&rft.aulast=Liddon&rft.aufirst=Nicole&rft.date=2012-01-01&rft.volume=42&rft.issue=1&rft.spage=44&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2011.09.024 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-01-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Condoms; Demography; Age; Multivariate analysis; Adolescence; Race differences; Vaccines; Sexual behavior; Races; Cancer; Ethnic groups; Sex; demography; sexual behavior; vaccines; wear; Insurance; Adolescents; Human papillomavirus DO - http://dx.doi.org/10.1016/j.amepre.2011.09.024 ER - TY - JOUR T1 - Use of Family History in Clinical Guidelines for Diabetes and Colorectal Cancer AN - 915483091; 16148903 AB - Family history is a risk factor for many chronic diseases and as such is often incorporated into clinical practice guidelines. Purpose: To assess the consistency of the use of family history in selected guidelines for colorectal cancer (CRC) and type 2 diabetes mellitus (T2DM) and to examine how these definitions influence their screening recommendations. Methods: Using a web-based search, guidelines issued between 2001 and 2011 from Australia, Canada, the United Kingdom, the U.S., and the WHO were reviewed. In total, 21 guidelines were found that included family history information (14 for CRC and seven for T2DM). For each guideline, the definition of family history and the way this definition influenced screening recommendations was recorded. Analyses were completed on May 2011. Results: Family history was defined most often as the presence of affected first-degree relatives; the number of such relatives and their ages at diagnosis were considered sometimes in making specific recommendations. The definition of family history and its impact on recommendations varied substantially, even for the same disease. Conclusions: Despite the importance of family history as a risk factor for CRC and T2DM, its use in screening recommendations is inconsistent among guidelines from major organizations; however, differences do not appear large enough to prevent achieving consensus among the guidelines for each disease. More standardized recommendations for use of family history in CRC and T2DM screening guidelines could enhance their utility for prevention. JF - American Journal of Preventive Medicine AU - Peterson, Brent A AU - Gwinn, Marta L AU - Valdez, Rodolfo A AD - Biology Department, Wisconsin Lutheran College, Milwaukee, Wisconsin, rvaldez@cdc.gov Y1 - 2012/01// PY - 2012 DA - Jan 2012 SP - 65 EP - 70 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 42 IS - 1 SN - 0749-3797, 0749-3797 KW - Health & Safety Science Abstracts; Risk Abstracts KW - Age KW - Colorectal carcinoma KW - Diabetes mellitus KW - Genetics KW - Guidelines KW - Prevention KW - Reviews KW - Risk factors KW - Standards KW - colorectal carcinoma KW - diabetes mellitus KW - guidelines KW - prevention KW - Australia KW - USA KW - Canada UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/915483091?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Use+of+Family+History+in+Clinical+Guidelines+for+Diabetes+and+Colorectal+Cancer&rft.au=Peterson%2C+Brent+A%3BGwinn%2C+Marta+L%3BValdez%2C+Rodolfo+A&rft.aulast=Peterson&rft.aufirst=Brent&rft.date=2012-01-01&rft.volume=42&rft.issue=1&rft.spage=65&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2011.08.017 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-01-01 N1 - Last updated - 2012-09-24 N1 - SubjectsTermNotLitGenreText - Age; Guidelines; Diabetes mellitus; Genetics; diabetes mellitus; Prevention; guidelines; colorectal carcinoma; Risk factors; Reviews; prevention; Colorectal carcinoma; Standards; USA; Canada; Australia DO - http://dx.doi.org/10.1016/j.amepre.2011.08.017 ER - TY - JOUR T1 - Using poison center data for national public health surveillance for chemical and poison exposure and associated illness. AN - 912108790; 21937144 AB - The National Poison Data System (NPDS) is a national near-real-time surveillance system that improves situational awareness for chemical and poison exposures, according to data from US poison centers. NPDS is the successor to the Toxic Exposure Surveillance System. The Centers for Disease Control and Prevention (CDC) use these data, which are owned and managed by the American Association of Poison Control Centers, to improve public health surveillance for chemical and poison exposures and associated illness, identify early markers of chemical events, and enhance situational awareness during outbreaks. Information recorded in this database is from self-reported calls from the public or health care professionals. In 2009, NPDS detected 22 events of public health significance and CDC used the system to monitor several multistate outbreaks. One of the limitations of the system is that exposures do not necessarily represent a poisoning. Incorporating NPDS data into the public health surveillance network and subsequently using NPDS to rapidly identify chemical and poison exposures exemplifies the importance of the poison centers and NPDS to public health surveillance. This integration provides the opportunity to improve the public health response to chemical and poison exposures, minimizes morbidity and mortality, and serves as an important step forward in surveillance technology and integration. Copyright © 2011 American College of Emergency Physicians. Published by Mosby, Inc. All rights reserved. JF - Annals of emergency medicine AU - Wolkin, Amy F AU - Martin, Colleen A AU - Law, Royal K AU - Schier, Josh G AU - Bronstein, Alvin C AD - National Center for Environmental Health/Agency for Toxic Substances and Disease Registry, Centers for Disease Control and Prevention, Atlanta, GA, USA. awolkin@cdc.gov Y1 - 2012/01// PY - 2012 DA - January 2012 SP - 56 EP - 61 VL - 59 IS - 1 KW - Abridged Index Medicus KW - Index Medicus KW - Environmental Exposure -- statistics & numerical data KW - Humans KW - Biosurveillance -- methods KW - Salmonella Food Poisoning -- epidemiology KW - Disease Outbreaks -- statistics & numerical data KW - United States -- epidemiology KW - Poison Control Centers -- statistics & numerical data KW - Poisoning -- epidemiology KW - Poisoning -- etiology KW - Population Surveillance -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/912108790?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annals+of+emergency+medicine&rft.atitle=Using+poison+center+data+for+national+public+health+surveillance+for+chemical+and+poison+exposure+and+associated+illness.&rft.au=Wolkin%2C+Amy+F%3BMartin%2C+Colleen+A%3BLaw%2C+Royal+K%3BSchier%2C+Josh+G%3BBronstein%2C+Alvin+C&rft.aulast=Wolkin&rft.aufirst=Amy&rft.date=2012-01-01&rft.volume=59&rft.issue=1&rft.spage=56&rft.isbn=&rft.btitle=&rft.title=Annals+of+emergency+medicine&rft.issn=1097-6760&rft_id=info:doi/10.1016%2Fj.annemergmed.2011.08.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-02-15 N1 - Date created - 2011-12-19 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Comment In: Ann Emerg Med. 2012 Jan;59(1):62-6 [22177679] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.annemergmed.2011.08.004 ER - TY - JOUR T1 - Maternal smokeless tobacco use in Alaska Native women and singleton infant birth size. AN - 911930086; 21902677 AB - To examine the effects of maternal prenatal smokeless tobacco use on infant birth size. A retrospective medical record review of 502 randomly selected deliveries. Singleton deliveries to Alaska Native women residing in a defined geographical region in western Alaska, 1997-2005. A regional medical center's electronic records were used to identify singleton deliveries. Data on maternal tobacco exposure and pregnancy outcomes were abstracted from medical records. Logistic models were used to estimate adjusted mean birthweight, length and head circumference for deliveries to women who used no tobacco (n=121), used smokeless tobacco (n=237) or smoked cigarettes (n=59). Differences in mean birthweight, length and head circumference, 95% confidence intervals and p-values were calculated using non-users as the reference group. Infant birthweight, crown-heel length and head circumference. After adjustment for gestational age and other potential confounders, the mean birthweight of infants of smokeless tobacco users was reduced by 78 g compared with that of infants of non-users (p=0.18) and by 331 g in infants of smokers (p<0.01). No association was found between maternal smokeless tobacco use and infant length or infant head circumference. We found a modest but non-significant reduction in the birthweight of infants of smokeless tobacco users compared with infants of tobacco non-users. Because smokeless tobacco contains many toxic compounds that could affect other pregnancy outcomes, results of this study should not be construed to mean that smokeless tobacco use is safe during pregnancy. © 2011 Nordic Federation of Societies of Obstetrics and Gynecology No claim to original US government works. JF - Acta obstetricia et gynecologica Scandinavica AU - England, Lucinda J AU - Kim, Shin Y AU - Shapiro-Mendoza, Carrie K AU - Wilson, Hoyt G AU - Kendrick, Juliette S AU - Satten, Glen A AU - Lewis, Claire A AU - Whittern, Persenia AU - Tucker, Myra J AU - Callaghan, William M AD - Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA 30030, USA. lbe9@cdc.gov Y1 - 2012/01// PY - 2012 DA - January 2012 SP - 93 EP - 103 VL - 91 IS - 1 KW - Index Medicus KW - Dose-Response Relationship, Drug KW - Humans KW - Infant, Newborn KW - Retrospective Studies KW - Smoking -- adverse effects KW - Cephalometry KW - Pregnancy KW - Logistic Models KW - Adult KW - Smoking -- ethnology KW - Alaska KW - Female KW - Male KW - Indians, North American KW - Tobacco, Smokeless -- adverse effects KW - Birth Weight -- drug effects KW - Body Height -- drug effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/911930086?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Acta+obstetricia+et+gynecologica+Scandinavica&rft.atitle=Maternal+smokeless+tobacco+use+in+Alaska+Native+women+and+singleton+infant+birth+size.&rft.au=England%2C+Lucinda+J%3BKim%2C+Shin+Y%3BShapiro-Mendoza%2C+Carrie+K%3BWilson%2C+Hoyt+G%3BKendrick%2C+Juliette+S%3BSatten%2C+Glen+A%3BLewis%2C+Claire+A%3BWhittern%2C+Persenia%3BTucker%2C+Myra+J%3BCallaghan%2C+William+M&rft.aulast=England&rft.aufirst=Lucinda&rft.date=2012-01-01&rft.volume=91&rft.issue=1&rft.spage=93&rft.isbn=&rft.btitle=&rft.title=Acta+obstetricia+et+gynecologica+Scandinavica&rft.issn=1600-0412&rft_id=info:doi/10.1111%2Fj.1600-0412.2011.01273.x LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-02-06 N1 - Date created - 2011-12-13 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1111/j.1600-0412.2011.01273.x ER - TY - JOUR T1 - Past and current alcohol consumption patterns and elevations in serum hepatic enzymes among US adults AN - 902376768; 15913660 AB - Objective: The aim of this study was to examine the association between patterns of past and current alcohol consumption and elevations in serum hepatic enzymes among a nationally representative sample of adults in the United States. Methods: We estimated the age-adjusted prevalence of elevated serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), and gamma-glutamyltransferase (GGT) among 8993 adults aged 20 years or older who participated in the 2005-2008 National Health and Nutrition Examination Survey (NHANES). We produced prevalence ratios by using patterns of alcohol consumption as a predictor; elevations in serum ALT, AST, and GGT were used as an outcome variable while adjusting for covariates in multivariate regression models. Results: The age-adjusted prevalence of elevated serum ALT, AST, and GGT in adults was 9.7%, 16.0%, and 8.6%, respectively. Male excessive current drinkers had 50%-71% and 75%-314% increased likelihoods of having elevated serum AST and GGT, respectively; female excessive drinkers with a history of consuming 5 or more drinks almost daily had a 226% increased likelihood of having elevated serum GGT, when compared to their respective counterparts who were lifetime abstainers. Conclusions: The results of this study indicate that elevations in serum hepatic enzymes, especially AST and GGT, are common in adults who are excessive current drinkers. There is evidence to suggest that excessive current drinkers with a history of protracted drinking are especially vulnerable to potential liver injury. These findings lend further support to the early identification of excessive drinkers who may have an increased risk for alcohol-related morbidity and mortality in health care settings. JF - Addictive Behaviors AU - Tsai, James AU - Ford, Earl S AU - Li, Chaoyang AU - Zhao, Guixiang AD - Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion Centers for Disease Control and Prevention, Atlanta, GA 30341, United States, jxt9@cdc.gov Y1 - 2012/01// PY - 2012 DA - Jan 2012 SP - 78 EP - 84 PB - Elsevier B.V., P.O. Box 800 Kidlington Oxford OX5 1DX United Kingdom VL - 37 IS - 1 SN - 0306-4603, 0306-4603 KW - Risk Abstracts KW - Alcohol KW - Historical account KW - Mortality KW - Enzymes KW - Nutrition KW - Morbidity KW - USA KW - Health care KW - Liver KW - vulnerability KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/902376768?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Addictive+Behaviors&rft.atitle=Past+and+current+alcohol+consumption+patterns+and+elevations+in+serum+hepatic+enzymes+among+US+adults&rft.au=Tsai%2C+James%3BFord%2C+Earl+S%3BLi%2C+Chaoyang%3BZhao%2C+Guixiang&rft.aulast=Tsai&rft.aufirst=James&rft.date=2012-01-01&rft.volume=37&rft.issue=1&rft.spage=78&rft.isbn=&rft.btitle=&rft.title=Addictive+Behaviors&rft.issn=03064603&rft_id=info:doi/10.1016%2Fj.addbeh.2011.09.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Mortality; Historical account; Alcohol; Health care; Liver; Enzymes; vulnerability; Nutrition; Morbidity; USA DO - http://dx.doi.org/10.1016/j.addbeh.2011.09.002 ER - TY - JOUR T1 - Some important oversights in the assessment of whole-body vibration exposure based on ISO-2631-1 AN - 899158641; 15705624 JF - Applied Ergonomics AU - Dong, Ren G AU - Welcome, Daniel E AU - McDowell, Thomas W Y1 - 2012/01// PY - 2012 DA - Jan 2012 SP - 268 EP - 269 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 43 IS - 1 SN - 0003-6870, 0003-6870 KW - Health & Safety Science Abstracts KW - Ergonomics KW - Vibration KW - H 10000:Ergonomics/Human Factors UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/899158641?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+Ergonomics&rft.atitle=Some+important+oversights+in+the+assessment+of+whole-body+vibration+exposure+based+on+ISO-2631-1&rft.au=Dong%2C+Ren+G%3BWelcome%2C+Daniel+E%3BMcDowell%2C+Thomas+W&rft.aulast=Dong&rft.aufirst=Ren&rft.date=2012-01-01&rft.volume=43&rft.issue=1&rft.spage=268&rft.isbn=&rft.btitle=&rft.title=Applied+Ergonomics&rft.issn=00036870&rft_id=info:doi/10.1016%2Fj.apergo.2011.05.005 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Vibration DO - http://dx.doi.org/10.1016/j.apergo.2011.05.005 ER - TY - JOUR T1 - Borrelia burgdorferi Visualized in Ixodes scapularis Tick Excrement by Immunofluorescence AN - 1717490265; PQ0001969632 AB - The enzootic cycle of Borrelia burgdorferi, the etiologic agent of Lyme disease, involves Ixodes spp. ticks and vertebrates. Resident tick Borrelia, harbored inside the midgut, are eventually expelled with the tick's saliva into the vertebrate host when a tick consumes a blood meal. During this 4- to 5-day feeding period I. scapularis will defecate onto the host's skin. Previously we detected borrelial DNA in tick feces throughout engorgement. In this study we report the microscopic examination for B. burgdorferi in nymphal excrement. Using immunofluorescence assays, we observed Borrelia in all mouse skin and capsule fecal swabs tested, although we could not culture the spirochetes. These results update our previous analysis by revealing that spirochetes can also be visualized in tick excrement. Furthermore, the results emphasize that borrelial contamination by defecation is a possibility, and that caution should be exercised by researchers investigating pathogen/host/vector interactions. The biological significance of the presence of non-culturable Borrelia in tick feces during engorgement is unclear. JF - Vector Borne and Zoonotic Diseases AU - Patton, Toni G AU - Brandt, Kevin S AU - Gilmore, Robert D, Jr AD - Microbiology and Pathogenesis Activity, Bacterial Diseases Branch, Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado. PY - 2012 SP - 1000 EP - 1003 PB - Mary Ann Liebert, Inc., 2 Madison Ave Larchmont NY 10538-1962 United States VL - 12 IS - 11 SN - 1530-3667, 1530-3667 KW - Microbiology Abstracts B: Bacteriology; Entomology Abstracts KW - Borrelia burgdorferi KW - Immunofluorescence KW - Ixodes scapularis KW - Tick feces KW - Ixodes KW - Feeding KW - Skin KW - Contamination KW - Defecation KW - Ixodidae KW - Vectors KW - Pathogens KW - Blood meals KW - Spirochetes KW - DNA KW - Saliva KW - Midgut KW - Feces KW - Lyme disease KW - Engorgement KW - J 02410:Animal Diseases KW - Z 05350:Medical, Veterinary, and Agricultural Entomology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1717490265?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vector+Borne+and+Zoonotic+Diseases&rft.atitle=Borrelia+burgdorferi+Visualized+in+Ixodes+scapularis+Tick+Excrement+by+Immunofluorescence&rft.au=Patton%2C+Toni+G%3BBrandt%2C+Kevin+S%3BGilmore%2C+Robert+D%2C+Jr&rft.aulast=Patton&rft.aufirst=Toni&rft.date=2012-01-01&rft.volume=12&rft.issue=11&rft.spage=1000&rft.isbn=&rft.btitle=&rft.title=Vector+Borne+and+Zoonotic+Diseases&rft.issn=15303667&rft_id=info:doi/10.1089%2Fvbz.2011.0922 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-09-01 N1 - Number of references - 10 N1 - Last updated - 2016-01-21 N1 - SubjectsTermNotLitGenreText - Feeding; Skin; Contamination; Defecation; Vectors; Blood meals; Immunofluorescence; Pathogens; Spirochetes; DNA; Midgut; Saliva; Feces; Engorgement; Lyme disease; Ixodes; Borrelia burgdorferi; Ixodidae; Ixodes scapularis DO - http://dx.doi.org/10.1089/vbz.2011.0922 ER - TY - JOUR T1 - Elevated cardiovascular risk among adults with obstructive and restrictive airway functioning in the United States: a cross-sectional study of the National Health and Nutrition Examination Survey from 2007-2010 AN - 1323817054; 17592539 AB - Background: Reasons for the excess risk for cardiovascular disease among people with chronic obstructive pulmonary disease remain unclear. Our objective was to examine the cardiovascular risk profile for adults with obstructive and restrictive impairments of lung functioning in a representative sample of adults from the United States. Methods: We used data from adults aged 20-79 years who participated in the National Health and Nutrition Examination Survey from 2007 to 2010 and had a pulmonary function test. The severity of obstructive impairment was defined by adapting the Global Initiative for Chronic Obstructive Lung Disease criteria. Results: Among 7249 participants, 80.9% had a normal pulmonary function test, 5.7% had a restrictive impairment, 7.9% had mild obstructive impairment, and 5.5% had moderate or severe/very severe obstructive impairment. Participants with obstructive impairment had high rates of smoking and increased serum concentrations of cotinine. Compared to participants with normal pulmonary functioning, participants with at least moderate obstructive impairment had elevated concentrations of C-reactive protein but lower concentrations of total cholesterol and non-high-density lipoprotein cholesterol. Among participants aged 50-74 years, participants with at least a moderate obstructive impairment or a restrictive impairment had an elevated predicted 10-year risk for cardiovascular disease. Conclusions: The high rates of smoking among adults with impaired pulmonary functioning, particularly those with obstructive impairment, point to a need for aggressive efforts to promote smoking cessation in these adults. In addition, adults with restrictive impairment may require increased attention to and fine-tuning of their cardiovascular risk profile. JF - Respiratory Research AU - Ford, Earl S AU - Wheaton, Anne G AU - Mannino, David M AU - Presley-Cantrell, Letitia AU - Li, Chaoyang AU - Croft, Janet B AD - Division of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA Y1 - 2012 PY - 2012 DA - 2012 SP - 115 PB - BioMed Central Ltd., Middlesex House London W1T 4LB United Kingdom VL - 13 IS - 1 SN - 1465-9921, 1465-9921 KW - Health & Safety Science Abstracts; Risk Abstracts KW - Smoking KW - Health risks KW - USA KW - Adaptability KW - Lung KW - Proteins KW - Respiratory function KW - Cardiovascular diseases KW - Cholesterol KW - Nutrition KW - Chronic obstructive pulmonary disease KW - H 1000:Occupational Safety and Health KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1323817054?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Respiratory+Research&rft.atitle=Elevated+cardiovascular+risk+among+adults+with+obstructive+and+restrictive+airway+functioning+in+the+United+States%3A+a+cross-sectional+study+of+the+National+Health+and+Nutrition+Examination+Survey+from+2007-2010&rft.au=Ford%2C+Earl+S%3BWheaton%2C+Anne+G%3BMannino%2C+David+M%3BPresley-Cantrell%2C+Letitia%3BLi%2C+Chaoyang%3BCroft%2C+Janet+B&rft.aulast=Ford&rft.aufirst=Earl&rft.date=2012-01-01&rft.volume=13&rft.issue=1&rft.spage=115&rft.isbn=&rft.btitle=&rft.title=Respiratory+Research&rft.issn=14659921&rft_id=info:doi/10.1186%2F1465-9921-13-115 L2 - http://respiratory-research.com/content/13/1/115 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-04-01 N1 - Number of references - 69 N1 - Last updated - 2013-12-04 N1 - SubjectsTermNotLitGenreText - Health risks; Smoking; Adaptability; Lung; Proteins; Cholesterol; Cardiovascular diseases; Respiratory function; Nutrition; Chronic obstructive pulmonary disease; USA DO - http://dx.doi.org/10.1186/1465-9921-13-115 ER - TY - JOUR T1 - Molecular surveillance of hepatitis C AN - 1285094591; 17592260 AB - With public health focusing on reduction of morbidity and mortality in the human population, transmission and virulence are major targets of molecular disease surveillance. Current molecular approaches to the detection of HCV transmission are based on phylogenetic analysis of intra-host HCV variants. Next-generation sequencing and mass spectrometry offer significant improvements in accuracy, throughput and cost of the transmission identification. Resistance to interferon (IFN) is an important virulence factor as it is essential for establishment of HCV infection and development of disease. IFN resistance has been shown to be associated quantitatively with epistatic connectivity among sites in the HCV genome, thus paving the way for genetic detection of virulence. Integration of genetic testing with computational models that automatically interpret the complex genetic parameters into transmission events and virulence is fundamental to comprehensive molecular surveillance of hepatitis C. JF - Antiviral Therapy AU - Khudyakov, Y Y1 - 2012 PY - 2012 DA - 2012 SP - 1465 EP - 1470 VL - 17 IS - 7 SN - 1359-6535, 1359-6535 KW - Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Genomes KW - virulence factors KW - Mass spectrometry KW - Disease resistance KW - Infection KW - Morbidity KW - Mass spectroscopy KW - Disease transmission KW - Public health KW - Integration KW - Epistasis KW - Genetic screening KW - Hepatitis C KW - Phylogeny KW - Mortality KW - Mathematical models KW - Human populations KW - Interferon KW - Hepatitis C virus KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - V 22310:Genetics, Taxonomy & Structure UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1285094591?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antiviral+Therapy&rft.atitle=Molecular+surveillance+of+hepatitis+C&rft.au=Khudyakov%2C+Y&rft.aulast=Khudyakov&rft.aufirst=Y&rft.date=2012-01-01&rft.volume=17&rft.issue=7&rft.spage=1465&rft.isbn=&rft.btitle=&rft.title=Antiviral+Therapy&rft.issn=13596535&rft_id=info:doi/10.3851%2FIMP2476 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-01 N1 - Last updated - 2013-12-04 N1 - SubjectsTermNotLitGenreText - Genomes; Phylogeny; Mortality; Mathematical models; virulence factors; Disease resistance; Infection; Mass spectroscopy; Morbidity; Public health; Integration; Interferon; Epistasis; Genetic screening; Hepatitis C; Human populations; Mass spectrometry; Disease transmission; Hepatitis C virus DO - http://dx.doi.org/10.3851/IMP2476 ER - TY - JOUR T1 - Trends in HIV Diagnoses and Testing Among U.S. Adolescents and Young Adults AN - 1081869689; 201206459 AB - The Centers for Disease Control and Prevention recommends routine HIV screening in health care settings. Using national surveillance data, we assessed trends in HIV diagnoses and testing frequency in youth aged 13-24 diagnosed with HIV in 2005-2008. Diagnosis rates increased among black (17.0% per year), Hispanic (13.5%), and white males (8.8%), with increases driven by men who have sex with men (MSM). A higher percentage of white males and MSM had previously been tested than their counterparts. No increases in diagnoses or differences in testing were observed among females. Intensified interventions are needed to reduce HIV infections and racial/ethnic disparities. Adapted from the source document. JF - AIDS and Behavior AU - Hall, H Irene AU - Walker, Frances AU - Shah, Daxa AU - Belle, Eboni AD - Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, MS E-47, 1600 Clifton Road NE, Atlanta, GA, 30333, USA Y1 - 2012/01// PY - 2012 DA - January 2012 SP - 36 EP - 43 PB - Springer, Dordrecht, The Netherlands VL - 16 IS - 1 SN - 1090-7165, 1090-7165 KW - Whites KW - Hispanic Americans KW - Males KW - Acquired Immune Deficiency Syndrome KW - Intervention KW - Racial Differences KW - Homosexuality KW - Adolescents KW - Health Care Services KW - article KW - 6126: acquired immune deficiency syndrome (AIDS) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1081869689?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocialservices&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Trends+in+HIV+Diagnoses+and+Testing+Among+U.S.+Adolescents+and+Young+Adults&rft.au=Hall%2C+H+Irene%3BWalker%2C+Frances%3BShah%2C+Daxa%3BBelle%2C+Eboni&rft.aulast=Hall&rft.aufirst=H&rft.date=2012-01-01&rft.volume=16&rft.issue=1&rft.spage=36&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-011-9944-8 LA - English DB - Social Services Abstracts N1 - Date revised - 2012-10-01 N1 - Last updated - 2016-09-28 N1 - CODEN - AIBEFC N1 - SubjectsTermNotLitGenreText - Acquired Immune Deficiency Syndrome; Homosexuality; Health Care Services; Males; Racial Differences; Intervention; Whites; Hispanic Americans; Adolescents DO - http://dx.doi.org/10.1007/s10461-011-9944-8 ER - TY - JOUR T1 - Combined television viewing and computer use and mortality from all-causes and diseases of the circulatory system among adults in the United States AN - 1028022805; 16858104 AB - Background: Watching television and using a computer are increasingly common sedentary behaviors. Whether or not prolonged screen time increases the risk for mortality remains uncertain. Methods: Mortality for 7,350 adults aged > or = 20 years who participated in the National Health and Nutrition Examination Survey during 1999-2002 and were followed through 2006 was examined. Participants were asked a single question about the amount of time they spent watching television or videos or using a computer during the past 30 days. Results: During a median follow-up of 5.8 years, 542 participants died. At baseline, 12.7% of participants reported watching television or using a computer less than 1 h per day, 16.4% did so for 1 h, 27.8% for 2 h, 18.7% for 3 h, 10.9% for 4 h, and 13.5% for 5 or more h. After extensive adjustment, the hazard ratio for all-cause mortality for the top category of exposure was 1.30 (95% confidence interval: 0.82, 2.05). No significant trend across categories of exposure was noted. The amount of screen time was also not significantly related to mortality from diseases of the circulatory system. Conclusions: In the present study, screen time did not significantly predict mortality from all-causes and diseases of the circulatory system. JF - BMC Public Health AU - Ford, Earl S AD - Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA Y1 - 2012 PY - 2012 DA - 2012 SP - 70 PB - BioMed Central Ltd., Middlesex House London W1T 4LB United Kingdom VL - 12 IS - 1 SN - 1471-2458, 1471-2458 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Mortality KW - USA KW - Television KW - Nutrition KW - H 12000:Epidemiology and Public Health KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1028022805?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=BMC+Public+Health&rft.atitle=Combined+television+viewing+and+computer+use+and+mortality+from+all-causes+and+diseases+of+the+circulatory+system+among+adults+in+the+United+States&rft.au=Ford%2C+Earl+S&rft.aulast=Ford&rft.aufirst=Earl&rft.date=2012-01-01&rft.volume=12&rft.issue=1&rft.spage=70&rft.isbn=&rft.btitle=&rft.title=BMC+Public+Health&rft.issn=14712458&rft_id=info:doi/10.1186%2F1471-2458-12-70 L2 - http://www.biomedcentral.com/1471-2458/12/70 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-07-01 N1 - Number of references - 22 N1 - Last updated - 2013-06-28 N1 - SubjectsTermNotLitGenreText - Mortality; Television; Nutrition; USA DO - http://dx.doi.org/10.1186/1471-2458-12-70 ER - TY - JOUR T1 - Adult Current Smoking: Differences in Definitions and Prevalence Estimates-NHIS and NSDUH, 2008 AN - 1022571033; 16809010 AB - Objectives . To compare prevalence estimates and assess issues related to the measurement of adult cigarette smoking in the National Health Interview Survey (NHIS) and the National Survey on Drug Use and Health (NSDUH). Methods . 2008 data on current cigarette smoking and current daily cigarette smoking among adults > or =18 years were compared. The standard NHIS current smoking definition, which screens for lifetime smoking > or =100 cigarettes, was used. For NSDUH, both the standard current smoking definition, which does not screen, and a modified definition applying the NHIS current smoking definition (i.e., with screen) were used. Results . NSDUH consistently yielded higher current cigarette smoking estimates than NHIS and lower daily smoking estimates. However, with use of the modified NSDUH current smoking definition, a notable number of subpopulation estimates became comparable between surveys. Younger adults and racial/ethnic minorities were most impacted by the lifetime smoking screen, with Hispanics being the most sensitive to differences in smoking variable definitions among all subgroups. Conclusions . Differences in current cigarette smoking definitions appear to have a greater impact on smoking estimates in some sub-populations than others. Survey mode differences may also limit intersurvey comparisons and trend analyses. Investigators are cautioned to use data most appropriate for their specific research questions. JF - Journal of Environmental and Public Health AU - Ryan, Heather AU - Trosclair, Angela AU - Gfroerer, Joe AD - Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Atlanta, GA 30341, USA, hryan@cdc.gov Y1 - 2012/01// PY - 2012 DA - Jan 2012 PB - Hindawi Publishing Corporation, P.O. Box 3079 Cuyahoga Falls OH 44223 United States VL - 2012 SN - 1687-9805, 1687-9805 KW - Environment Abstracts KW - subpopulations KW - Cigarette smoking KW - Drug abuse KW - Ethnic groups KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1022571033?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+and+Public+Health&rft.atitle=Adult+Current+Smoking%3A+Differences+in+Definitions+and+Prevalence+Estimates-NHIS+and+NSDUH%2C+2008&rft.au=Ryan%2C+Heather%3BTrosclair%2C+Angela%3BGfroerer%2C+Joe&rft.aulast=Ryan&rft.aufirst=Heather&rft.date=2012-01-01&rft.volume=2012&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+and+Public+Health&rft.issn=16879805&rft_id=info:doi/10.1155%2F2012%2F918368 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-06-01 N1 - Number of references - 47 N1 - Last updated - 2014-10-02 N1 - SubjectsTermNotLitGenreText - subpopulations; Cigarette smoking; Drug abuse; Ethnic groups DO - http://dx.doi.org/10.1155/2012/918368 ER - TY - JOUR T1 - Risk of Bottle-feeding for Rapid Weight Gain During the First Year of Life AN - 1017965202; 16669204 AB - OBJECTIVE: To better understand the mechanisms behind breastfeeding and childhood obesity, we assessed the association of weight gain with the mode of milk delivery aside from the type of milk given to infants. DESIGN: A longitudinal study of infants followed up from birth to age 1 year. Multilevel analyses were conducted to estimate infant weight gain by type of milk and feeding mode. SETTING: Pregnant women were recruited from a consumer mail panel throughout the United States between May 2005 and June 2007. PARTICIPANTS: One thousand eight hundred ninety nine infants with at least 3 weight measurements reported during the first year. Main Exposures Six mutually exclusive feeding categories and proportions of milk feedings given as breastmilk or by bottle. MAIN OUTCOME MEASURES: Weight measurements reported on 3-, 5-, 7-, and 12-month surveys. RESULTS: Compared with infants fed at the breast, infants fed only by bottle gained 71 or 89 g more per month when fed nonhuman milk only (P < .001) or human milk only (P = .02), respectively. Weight gain was negatively associated with proportion of breastmilk feedings, but it was positively associated with proportion of bottle-feedings among those who received mostly breastmilk. Among infants fed only breastmilk, monthly weight gain increased from 729 g when few feedings were by bottle to 780 g when most feedings were by bottle. CONCLUSIONS: Infant weight gain might be associated not only with type of milk consumed but also with mode of milk delivery. Regardless of milk type in the bottle, bottle-feeding might be distinct from feeding at the breast in its effect on infants' weight gain. JF - Archives of Pediatrics & Adolescent Medicine AU - Li, Ruowei AU - Magadia, Joselito AU - Fein, Sara B AU - Grummer-Strawn, Laurence M AD - Author Affiliations: National Center for Chronic Disease Prevention and Health Promotion Y1 - 2012 PY - 2012 DA - 2012 SP - 431 EP - 436 PB - American Medical Association, 515 N. State St. Chicago IL 60610 United States VL - 166 IS - 5 SN - 1072-4710, 1072-4710 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Adolescents KW - Breast feeding KW - Breast milk KW - Infants KW - Milk KW - body weight KW - feeding KW - longitudinal studies KW - obesity KW - USA KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1017965202?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Archives+of+Pediatrics+%26+Adolescent+Medicine&rft.atitle=Risk+of+Bottle-feeding+for+Rapid+Weight+Gain+During+the+First+Year+of+Life&rft.au=Li%2C+Ruowei%3BMagadia%2C+Joselito%3BFein%2C+Sara+B%3BGrummer-Strawn%2C+Laurence+M&rft.aulast=Li&rft.aufirst=Ruowei&rft.date=2012-01-01&rft.volume=166&rft.issue=5&rft.spage=431&rft.isbn=&rft.btitle=&rft.title=Archives+of+Pediatrics+%26+Adolescent+Medicine&rft.issn=10724710&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2012-06-01 N1 - SubjectsTermNotLitGenreText - Milk; obesity; Breast milk; feeding; Breast feeding; body weight; Adolescents; longitudinal studies; Infants; USA ER - TY - JOUR T1 - Utilization of two web-based continuing education courses evaluated by Markov chain model AN - 1014109775; 16559516 AB - OBJECTIVES: To evaluate the web structure of two web-based continuing education courses, identify problems and assess the effects of web site modifications. DESIGN: Markov chain models were built from 2008 web usage data to evaluate the courses' web structure and navigation patterns. The web site was then modified to resolve identified design issues and the improvement in user activity over the subsequent 12 months was quantitatively evaluated. MEASUREMENTS: Web navigation paths were collected between 2008 and 2010. The probability of navigating from one web page to another was analyzed. RESULTS: The continuing education courses' sequential structure design was clearly reflected in the resulting actual web usage models, and none of the skip transitions provided was heavily used. The web navigation patterns of the two different continuing education courses were similar. Two possible design flaws were identified and fixed in only one of the two courses. Over the following 12 months, the drop-out rate in the modified course significantly decreased from 41% to 35%, but remained unchanged in the unmodified course. The web improvement effects were further verified via a second-order Markov chain model. CONCLUSIONS: The results imply that differences in web content have less impact than web structure design on how learners navigate through continuing education courses. Evaluation of user navigation can help identify web design flaws and guide modifications. This study showed that Markov chain models provide a valuable tool to evaluate web-based education courses. Both the results and techniques in this study would be very useful for public health education and research specialists. JF - Journal of the American Medical Informatics Association AU - Tian, Hao AU - Lin, Jin-Mann S AU - Reeves, William C AD - Chronic Viral Diseases Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, Georgia, USA Y1 - 2012 PY - 2012 DA - 2012 SP - 489 EP - 494 PB - American Medical Informatics Association, 4915 St. Elmo Ave. Bethesda MD 20814 United States VL - 19 IS - 3 SN - 1067-5027, 1067-5027 KW - Biotechnology and Bioengineering Abstracts KW - Data processing KW - Informatics KW - Mathematical models KW - Models KW - Public health KW - W 30960:Bioinformatics & Computer Applications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1014109775?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+American+Medical+Informatics+Association&rft.atitle=Utilization+of+two+web-based+continuing+education+courses+evaluated+by+Markov+chain+model&rft.au=Tian%2C+Hao%3BLin%2C+Jin-Mann+S%3BReeves%2C+William+C&rft.aulast=Tian&rft.aufirst=Hao&rft.date=2012-01-01&rft.volume=19&rft.issue=3&rft.spage=489&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+American+Medical+Informatics+Association&rft.issn=10675027&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - Data processing; Mathematical models; Informatics; Models; Public health ER - TY - JOUR T1 - Moraxella catarrhalis as a respiratory pathogen AN - 926892233; 16373333 AB - Background: Moraxella catarrhalis is gaining significance as a pathogen over few decades because of increased rate of isolation in respiratory specimens and due to emergence of multidrug resistant strains. Therefore, appropriate antimicrobial agents are required for eradication and prevention of spread of the organism. Material and Methods: -The study was conducted over 1-year period inpatients of lower respiratory tract infections (L.R.T.I.) in P.G.I.M.S. Rohtak (Haryana). Assessment of clinical significance of M. catarrhalis was ascertained on the basis of preformed criteria. Results: A total of 63 clinically significant M. catarrhalis were isolated from a tertiary care hospital. The isolates showed maximum resistance to cotrimoxazole (82.5%), pencillin (77.7%), and ampicillin (71.4%) while susceptibility was maximum to cefotaxime (87.3%) followed by tetracycline (85.7%) ciprofloxacin (84.1%), erythromycin (80.9%) amikacin (79.3%), gentamycin (77.7%), and cefazolin (76.2%). Multidrug resistance to >3 antimicrobials was seen in 22 (34.9%) of cases. Conclusions: Predominant or pure growth of M. catarrhalis in throat swabs from cases of L.R.T.I. should be reported and treated by microbiologist and clinician respectively. Antibiotic therapy should be decided based on sensitivity report for rapid respose and recovery of patients. JF - Indian Journal of Pathology and Microbiology AU - Gupta, N AU - Arora, S AU - Kundra, S AD - Zoonosis Divison, National Center for Disease Control (NCDC), 22 Shamnath Marg, Delhi, India Y1 - 2011/12// PY - 2011 DA - Dec 2011 SP - 769 EP - 771 VL - 54 IS - 4 SN - 0377-4929, 0377-4929 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology KW - Cefotaxime KW - Pharynx KW - Amikacin KW - Moraxella catarrhalis KW - Ampicillin KW - Antibiotics KW - cotrimoxazole KW - Pathogens KW - Infection KW - Erythromycin KW - Tetracyclines KW - Antimicrobial agents KW - Respiratory tract diseases KW - Ciprofloxacin KW - Cefazolin KW - Multidrug resistance KW - Hospitals KW - A 01340:Antibiotics & Antimicrobials KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/926892233?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Indian+Journal+of+Pathology+and+Microbiology&rft.atitle=Moraxella+catarrhalis+as+a+respiratory+pathogen&rft.au=Gupta%2C+N%3BArora%2C+S%3BKundra%2C+S&rft.aulast=Gupta&rft.aufirst=N&rft.date=2011-12-01&rft.volume=54&rft.issue=4&rft.spage=769&rft.isbn=&rft.btitle=&rft.title=Indian+Journal+of+Pathology+and+Microbiology&rft.issn=03774929&rft_id=info:doi/10.4103%2F0377-4929.91496 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2012-04-06 N1 - SubjectsTermNotLitGenreText - Pharynx; Cefotaxime; Amikacin; Ampicillin; cotrimoxazole; Antibiotics; Pathogens; Tetracyclines; Erythromycin; Infection; Antimicrobial agents; Ciprofloxacin; Respiratory tract diseases; Cefazolin; Multidrug resistance; Hospitals; Moraxella catarrhalis DO - http://dx.doi.org/10.4103/0377-4929.91496 ER - TY - JOUR T1 - Impact of hysterectomy and bilateral oophorectomy prevalence on rates of cervical, uterine, and ovarian cancer among American Indian and Alaska Native women, 1999-2004 AN - 926892044; 16333536 AB - Objective: To present more accurate incidence rates of cervical, uterine, and ovarian cancer by geographic region in American Indian/Alaska Native (AI/AN) women. Methods: The authors used data from central cancer registries linked to Indian Health Service (IHS) patient registration database, the Behavioral Risk Factor Surveillance System, IHS National Data Warehouse, and the National Hospital Discharge Survey. Cancer incidence rates were adjusted for hysterectomy and oophorectomy prevalence and presented by region for non-Hispanic White (NHW) and AI/AN women. Results: AI/AN women had a higher prevalence of hysterectomy (23.1%) compared with NHW women (20.9%). Correcting cancer rates for population-at-risk significantly increased the cancer incidence rates among AI/AN women: 43% for cervical cancer, 67% for uterine cancer, and 37% for ovarian cancer. Risk-correction led to increased differences in cervical cancer incidence between AI/AN and NHW women in certain regions. Conclusions: Current reporting of cervical, uterine, and ovarian cancer underestimates the incidence in women at risk and can affect the measure of cancer disparities. Improved cancer surveillance using methodology to correct for population-at-risk may better inform disease control priorities for AI/AN populations. JF - Cancer Causes & Control AU - Wong, Charlene A AU - Jim, Melissa A AU - King, Jessica AU - Tom-Orme, Lillian AU - Henderson, Jeffrey A AU - Saraiya, Mona AU - Richardson, Lisa C AU - Layne, Larry AU - Suryaprasad, Anil AU - Espey, David K AD - Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers of Disease Control and Prevention, Atlanta, GA, USA, david.espey@ihs.gov Y1 - 2011/12// PY - 2011 DA - Dec 2011 SP - 1681 EP - 1689 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 22 IS - 12 SN - 0957-5243, 0957-5243 KW - Health & Safety Science Abstracts; Risk Abstracts KW - Cancer KW - Disease control KW - Ethnic groups KW - Females KW - Hospitals KW - Ovarian carcinoma KW - Risk factors KW - disease control KW - ovarian carcinoma KW - INE, USA, Alaska KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/926892044?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cancer+Causes+%26+Control&rft.atitle=Impact+of+hysterectomy+and+bilateral+oophorectomy+prevalence+on+rates+of+cervical%2C+uterine%2C+and+ovarian+cancer+among+American+Indian+and+Alaska+Native+women%2C+1999-2004&rft.au=Wong%2C+Charlene+A%3BJim%2C+Melissa+A%3BKing%2C+Jessica%3BTom-Orme%2C+Lillian%3BHenderson%2C+Jeffrey+A%3BSaraiya%2C+Mona%3BRichardson%2C+Lisa+C%3BLayne%2C+Larry%3BSuryaprasad%2C+Anil%3BEspey%2C+David+K&rft.aulast=Wong&rft.aufirst=Charlene&rft.date=2011-12-01&rft.volume=22&rft.issue=12&rft.spage=1681&rft.isbn=&rft.btitle=&rft.title=Cancer+Causes+%26+Control&rft.issn=09575243&rft_id=info:doi/10.1007%2Fs10552-011-9844-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2012-08-10 N1 - SubjectsTermNotLitGenreText - Risk factors; ovarian carcinoma; Disease control; Ovarian carcinoma; Females; disease control; Ethnic groups; Cancer; Hospitals; INE, USA, Alaska DO - http://dx.doi.org/10.1007/s10552-011-9844-2 ER - TY - JOUR T1 - A Qualitative Analysis of Lung Cancer Screening Practices by Primary Care Physicians AN - 926883552; 16332479 AB - Lung cancer is the leading cause of cancer death in the United States, but no scientific organization currently recommends screening because of limited evidence for its effectiveness. Despite this, physicians often order screening tests such as chest X-rays and computerized tomography scans for their patients. Limited information is available about how physicians decide when to order these tests. To identify factors that affect whether physicians' screen patients for lung cancer, we conducted five 75-min telephone-based focus groups with 28 US primary care physicians and used inductive qualitative research methods to analyze their responses. We identified seven factors that influenced these physicians' decisions about screening patients for lung cancer: (1) their perception of a screening test's effectiveness, (2) their attitude toward recommended screening guidelines, (3) their practice experience, (4) their perception of a patient's risk for lung cancer, (5) reimbursement and payment for screening, (6) their concern about litigation, and (7) whether a patient requested screening. Because these factors may have conflicting effects on physicians' decisions to order screening tests, physicians may struggle in determining when screening for lung cancer is appropriate. We recommend (1) more clinician education, beginning in medical school, about the existing evidence related to lung cancer screening, with emphasis on the benefit of and training in tobacco use prevention and cessation, (2) more patient education about the benefits and limitations of screening, (3) further studies about the effect of patients' requests to be screened on physicians' decisions to order screening tests, and (4) larger, quantitative studies to follow up on our formative data. JF - Journal of Community Health AU - Henderson, Susan AU - DeGroff, Amy AU - Richards, Thomas B AU - Kish-Doto, Julia AU - Soloe, Cindy AU - Heminger, Christina AU - Rohan, Elizabeth AD - Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, CDC, 4770 Buford Hwy, NE, MS K-57, Atlanta, GA, 30341, USA, IRV5@cdc.gov Y1 - 2011/12// PY - 2011 DA - Dec 2011 SP - 949 EP - 956 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 36 IS - 6 SN - 0094-5145, 0094-5145 KW - Risk Abstracts KW - Cancer KW - Education KW - Litigation KW - Lung cancer KW - Mortality KW - Perception KW - Tobacco KW - attitudes KW - schools KW - USA KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/926883552?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Community+Health&rft.atitle=A+Qualitative+Analysis+of+Lung+Cancer+Screening+Practices+by+Primary+Care+Physicians&rft.au=Henderson%2C+Susan%3BDeGroff%2C+Amy%3BRichards%2C+Thomas+B%3BKish-Doto%2C+Julia%3BSoloe%2C+Cindy%3BHeminger%2C+Christina%3BRohan%2C+Elizabeth&rft.aulast=Henderson&rft.aufirst=Susan&rft.date=2011-12-01&rft.volume=36&rft.issue=6&rft.spage=949&rft.isbn=&rft.btitle=&rft.title=Journal+of+Community+Health&rft.issn=00945145&rft_id=info:doi/10.1007%2Fs10900-011-9394-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2012-05-18 N1 - SubjectsTermNotLitGenreText - Mortality; Education; schools; Perception; Tobacco; Litigation; attitudes; Cancer; Lung cancer; USA DO - http://dx.doi.org/10.1007/s10900-011-9394-2 ER - TY - JOUR T1 - Is Injection Serosorting Occurring among HIV-Positive Injection Drug Users? Comparison by Injection Partner's HIV Status AN - 926882751; 16357246 AB - Research needs to build evidence for the roles that HIV status of injection partners may or may not play in injection risk behaviors of injection drug users (IDUs). Using baseline data collected from a randomized controlled study (INSPIRE) conducted in four cities (Baltimore, Miami, New York, and San Francisco) from 2001 to 2005, we categorized 759 primarily heterosexual HIV-positive IDUs into four groups based on HIV serostatus of drug injection partners. Thirty-two percent of the sample injected exclusively with HIV-positive partners in the past 3 months and more than 60% had risky injection behavior with these partners. Eight percent injected exclusively with HIV-negative partners and 49% injected with any unknown status partners. The remaining 11% reported having both HIV-positive and -negative injection partners, but no partners of unknown HIV status. Riskier injection behavior was found among the group with mixed status partners. The risk among the group with any unknown status partners appeared to be driven by the greater number of injection partners. No major group differences were observed in socio-demographic and psychosocial factors. Our analysis suggests that serosorting appeared to be occurring among some, but not an overwhelming majority of HIV-positive IDUs, and knowledge of HIV status of all injection partners per se did not appear to be as important as knowledge of sexual partner's HIV status in its association with risk behavior. JF - Journal of Urban Health AU - Mizuno, Yuko AU - Purcell, David W AU - Metsch, Lisa R AU - Gomez, Cynthia A AU - Knowlton, Amy R AU - Latka, Mary H AD - Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA, ymizuno@cdc.gov Y1 - 2011/12// PY - 2011 DA - Dec 2011 SP - 1031 EP - 1043 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 88 IS - 6 SN - 1099-3460, 1099-3460 KW - Risk Abstracts KW - sexual behavior KW - Human immunodeficiency virus KW - USA, Maryland, Baltimore KW - USA, California, San Francisco KW - Drug abuse KW - Drugs KW - USA, Florida, Miami KW - USA, New York KW - Urban areas KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/926882751?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Urban+Health&rft.atitle=Is+Injection+Serosorting+Occurring+among+HIV-Positive+Injection+Drug+Users%3F+Comparison+by+Injection+Partner%27s+HIV+Status&rft.au=Mizuno%2C+Yuko%3BPurcell%2C+David+W%3BMetsch%2C+Lisa+R%3BGomez%2C+Cynthia+A%3BKnowlton%2C+Amy+R%3BLatka%2C+Mary+H&rft.aulast=Mizuno&rft.aufirst=Yuko&rft.date=2011-12-01&rft.volume=88&rft.issue=6&rft.spage=1031&rft.isbn=&rft.btitle=&rft.title=Journal+of+Urban+Health&rft.issn=10993460&rft_id=info:doi/10.1007%2Fs11524-011-9578-1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - sexual behavior; Human immunodeficiency virus; Drug abuse; Drugs; Urban areas; USA, Maryland, Baltimore; USA, California, San Francisco; USA, Florida, Miami; USA, New York DO - http://dx.doi.org/10.1007/s11524-011-9578-1 ER - TY - JOUR T1 - Epidemic Assistance by the Centers for Disease Control and Prevention: Role of the Epidemic Intelligence Service, 1946-2005 AN - 926880810; 16123505 AB - Since 1946, the Centers for Disease Control and Prevention has responded to urgent requests from US states, federal agencies, and international organizations through epidemic-assistance investigations (Epi-Aids). The authors describe the first 60 years of Epi-Aids, breadth of problems addressed, evolution of methodologies, scope of activities, and impact of investigations on population health. They reviewed Epi-Aid reports and EIS Bulletins, contacted current and former Epidemic Intelligence Service staff, and systematically searched the PubMed and Web of Science databases. They abstracted information on dates, location, staff involved, health problems, methods, and impacts of investigations according to a preplanned protocol. They assessed the methods presented as well as the quality of reports. During 1946-2005, a total of 4,484 investigations of health events were initiated by 2,815 Epidemic Intelligence Service officers. In the early years, the majority were in response to infectious agents, although environmental problems emerged. Investigations in subsequent years focused on occupational conditions, birth defects, reproductive health, tobacco use, cancer, violence, legal debate, and terrorism. These Epi-Aids heralded expansion of the agency's mission and presented new methods in statistics and epidemiology. Recommendations from Epi-Aids led to policy implementation, evaluation, or modification. Epi-Aids provide the Centers for Disease Control and Prevention with the agility to respond rapidly to public health crises. JF - American Journal of Epidemiology AU - Thacker, Stephen B AU - Stroup, Donna F AU - Sencer, David J Y1 - 2011/12/01/ PY - 2011 DA - 2011 Dec 01 SP - S4 EP - S15 PB - Oxford University Press, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 174 IS - suppl_11 SN - 0002-9262, 0002-9262 KW - Health & Safety Science Abstracts KW - prevention KW - Tobacco KW - Congenital defects KW - Reproduction KW - disease control KW - Cancer KW - international organizations KW - intelligence KW - Public health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/926880810?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Epidemiology&rft.atitle=Epidemic+Assistance+by+the+Centers+for+Disease+Control+and+Prevention%3A+Role+of+the+Epidemic+Intelligence+Service%2C+1946-2005&rft.au=Thacker%2C+Stephen+B%3BStroup%2C+Donna+F%3BSencer%2C+David+J&rft.aulast=Thacker&rft.aufirst=Stephen&rft.date=2011-12-01&rft.volume=174&rft.issue=suppl_11&rft.spage=S4&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Epidemiology&rft.issn=00029262&rft_id=info:doi/10.1093%2Faje%2Fkwr307 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2013-11-04 N1 - SubjectsTermNotLitGenreText - Tobacco; prevention; Congenital defects; Reproduction; disease control; international organizations; Cancer; Public health; intelligence DO - http://dx.doi.org/10.1093/aje/kwr307 ER - TY - JOUR T1 - Experimental infection of Swiss Webster mice with four rat bartonella strains: Host specificity, bacteremia kinetics, dose dependent response, and histopathology AN - 918067057; 16091692 AB - Groups of Swiss Webster outbred mice were each inoculated with one of four bartonella strains originally isolated from Rattus spp. at doses ranging from 10 super(1 to 10) super(7) bacteria per mouse. One strain, Rn1691yn (Bartonella coopersplainensis-like), infected mice and produced bacteremias at levels up to 10 super(5 bacteria/ml of blood and from 3 to 8 weeks duration. A dose dependent response was also observed with differing proportions of mice bacteremic following inoculation at different doses. In addition weeks-to-months long lags in bacteremia manifestation occurred following lower dose exposures. The possibility of bacterial transmission from bacteremic mice to uninfected cagemates was assessed and no naive mice became infected from contacts with infected mice. Finally, a subset of bacteremic mice inoculated with high doses of Rn1691yn were examined histopathologically and multifocal, granulomatous lesions were detected in both liver and kidneys. The host specificity and infectivity of the strains is discussed in relation to their potential for zoonotic transmission to incidental hosts.) JF - Comparative Immunology, Microbiology and Infectious Diseases AU - Colton, Leah AU - Zeidner, Nordin AU - Kosoy, Michael Y AD - Bacterial Diseases Branch, Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, 3150 Rampart Road, Fort Collins, CO 80521, USA, ant6@cdc.gov Y1 - 2011/12// PY - 2011 DA - Dec 2011 SP - 465 EP - 473 PB - Elsevier B.V., P.O. Box 800 Kidlington Oxford OX5 1DX United Kingdom VL - 34 IS - 6 SN - 0147-9571, 0147-9571 KW - Microbiology Abstracts B: Bacteriology KW - Host specificity KW - Experimental infection KW - Bartonella KW - Bacteremia KW - Disease transmission KW - Rattus KW - Blood KW - Infectivity KW - Kinetics KW - Kidney KW - Liver KW - Inoculation KW - J 02410:Animal Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/918067057?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Comparative+Immunology%2C+Microbiology+and+Infectious+Diseases&rft.atitle=Experimental+infection+of+Swiss+Webster+mice+with+four+rat+bartonella+strains%3A+Host+specificity%2C+bacteremia+kinetics%2C+dose+dependent+response%2C+and+histopathology&rft.au=Colton%2C+Leah%3BZeidner%2C+Nordin%3BKosoy%2C+Michael+Y&rft.aulast=Colton&rft.aufirst=Leah&rft.date=2011-12-01&rft.volume=34&rft.issue=6&rft.spage=465&rft.isbn=&rft.btitle=&rft.title=Comparative+Immunology%2C+Microbiology+and+Infectious+Diseases&rft.issn=01479571&rft_id=info:doi/10.1016%2Fj.cimid.2011.08.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-01-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Blood; Host specificity; Experimental infection; Infectivity; Kinetics; Inoculation; Liver; Kidney; Bacteremia; Disease transmission; Rattus; Bartonella DO - http://dx.doi.org/10.1016/j.cimid.2011.08.001 ER - TY - JOUR T1 - Environmental- and Injury-related Epidemic-Assistance Investigations, 1946-2005 AN - 918066800; 16123510 AB - This paper summarizes environmental investigations (n = 458) conducted during the first 60 years of the epidemic-assistance investigation program at the Centers for Disease Control and Prevention. These investigations were grouped into 10 categories: toxic chemicals (n = 102), indoor air quality and outdoor air toxics (n = 21), new or rare epidemic diseases and unexplained syndromes (n = 29), natural disasters (n = 81), terrorism and unintentional human-made disasters (n = 9), substance use and abuse (n = 13), environmental aspects of infectious disease (n = 132), those affecting neonates and infants (n = 11), violence and injuries (n = 51), and miscellaneous (n = 9). Among the most important or prominent were studies of lead and arsenic toxicity at smelters, mercury in paint and beauty creams, dioxin in waste oil in Missouri, polychlorinated biphenyls and multiple other toxic chemicals, global pesticide poisoning outbreaks, hepatic angiosarcoma among vinyl chloride workers, toxic oil syndrome in Spain, eosinophilia-myalgia syndrome from contaminated L-tryptophan, diethylene glycol poisoning in Haiti, aflatoxicosis in Kenya, Gulf War illness among veterans, impact and needs assessments during natural disasters (e.g., Hurricane Katrina (2005) and the Mount St. Helens volcano eruptions (1980)), risk factors for heat-related mortality, domestic and international terrorist attacks, Parkinsonism related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in California, and unintentional injury- and violence-related events. JF - American Journal of Epidemiology AU - Falk, Henry AU - Briss, Peter Y1 - 2011/12/01/ PY - 2011 DA - 2011 Dec 01 SP - S65 EP - S79 PB - Oxford University Press, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 174 IS - suppl_11 SN - 0002-9262, 0002-9262 KW - Risk Abstracts KW - Chemicals KW - terrorism KW - natural disasters KW - Spain KW - Poisoning KW - Toxicity KW - disease control KW - Lead KW - USA, Washington, Mount St. Helens KW - Kenya KW - INE, USA, California KW - prevention KW - USA, Missouri KW - ASW, Caribbean Sea, Greater Antilles, Haiti KW - Paints KW - Infants KW - R2 23050:Environment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/918066800?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Epidemiology&rft.atitle=Environmental-+and+Injury-related+Epidemic-Assistance+Investigations%2C+1946-2005&rft.au=Falk%2C+Henry%3BBriss%2C+Peter&rft.aulast=Falk&rft.aufirst=Henry&rft.date=2011-12-01&rft.volume=174&rft.issue=suppl_11&rft.spage=S65&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Epidemiology&rft.issn=00029262&rft_id=info:doi/10.1093%2Faje%2Fkwr313 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-01-01 N1 - Last updated - 2013-11-04 N1 - SubjectsTermNotLitGenreText - Chemicals; terrorism; natural disasters; prevention; Poisoning; Toxicity; disease control; Lead; Infants; Paints; USA, Washington, Mount St. Helens; Kenya; Spain; INE, USA, California; USA, Missouri; ASW, Caribbean Sea, Greater Antilles, Haiti DO - http://dx.doi.org/10.1093/aje/kwr313 ER - TY - JOUR T1 - Epidemic Intelligence Service Investigations of Respiratory Illness, 1946-2005 AN - 918066791; 16123508 AB - Infectious respiratory pathogens were the suspected cause of 480 outbreaks investigated by the Centers for Disease Control and Prevention's Epidemic Intelligence Service officers during 1946-2005. All epidemic-assistance investigation reports and associated articles from scientific journals were reviewed. Investigations identified 25 different infectious respiratory pathogens including, most frequently, tuberculosis, influenza, and legionellosis. Other bacterial-, viral-, and fungal-related pathogens also were identified. Epidemic-assistance investigations were notable for first identifying Legionnaires disease and Pontiac fever, hantavirus pulmonary syndrome, and new strains of human and avian influenza, as well as emerging challenges (e.g., multidrug-resistant tuberculosis and pneumococcus). The investigations provided clinical insights into such diseases as pulmonary anthrax and identified high risks of serious respiratory illnesses for persons infected with human immunodeficiency virus, other immunocompromised persons, and persons with diabetes. They identified settings placing persons at high risk of acquiring disease, including nursing homes, prisons, homeless shelters, and hospitals. Travel also placed persons at risk. Key environmental factors related to spread of diseases and occupational risks for brucellosis and psittacosis were identified. The outbreak investigations constitute a wealth of prevention experience and provide the basis for recommendations to mitigate outbreaks and reduce future risks. JF - American Journal of Epidemiology AU - Hadler, Stephen C AU - Castro, Kenneth G AU - Dowdle, Walter AU - Hicks, Lauri AU - Noble, Gary AU - Ridzon, Renee Y1 - 2011/12/01/ PY - 2011 DA - 2011 Dec 01 SP - S36 EP - S46 PB - Oxford University Press, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 174 IS - suppl_11 SN - 0002-9262, 0002-9262 KW - Environment Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - environmental factors KW - Mycobacterium KW - Pathogens KW - outbreaks KW - Legionnaire's disease KW - influenza KW - tuberculosis KW - Human immunodeficiency virus KW - prevention KW - Hantavirus KW - intelligence KW - Hospitals KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/918066791?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Epidemiology&rft.atitle=Epidemic+Intelligence+Service+Investigations+of+Respiratory+Illness%2C+1946-2005&rft.au=Hadler%2C+Stephen+C%3BCastro%2C+Kenneth+G%3BDowdle%2C+Walter%3BHicks%2C+Lauri%3BNoble%2C+Gary%3BRidzon%2C+Renee&rft.aulast=Hadler&rft.aufirst=Stephen&rft.date=2011-12-01&rft.volume=174&rft.issue=suppl_11&rft.spage=S36&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Epidemiology&rft.issn=00029262&rft_id=info:doi/10.1093%2Faje%2Fkwr309 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-01-01 N1 - Last updated - 2013-11-04 N1 - SubjectsTermNotLitGenreText - tuberculosis; environmental factors; prevention; outbreaks; Pathogens; Legionnaire's disease; Hospitals; influenza; intelligence; Mycobacterium; Human immunodeficiency virus; Hantavirus DO - http://dx.doi.org/10.1093/aje/kwr309 ER - TY - JOUR T1 - Quadriplex real-time polymerase chain reaction (lytA, mef, erm, pbp2bwt) for pneumococcal detection and assessment of antibiotic susceptibility AN - 918061396; 16058061 AB - A quadriplex real-time polymerase chain reaction assay was developed for detecting pneumococci, penicillin susceptibility, and macrolide/lincosamide resistance. The assay was sensitive for all 4 targets (<10 copies) and correlated with antimicrobial susceptibilities in 172/180 isolates and 28/29 culture-positive clinical specimens. For 29 lytA-positive culture-negative specimens, the assay allowed interpretation of antimicrobial susceptibility. JF - Diagnostic Microbiology and Infectious Disease AU - Srinivasan, Velusamy AU - du Plessis, Mignon AU - Beall, Bernard W AU - McGee, Lesley AD - Respiratory Diseases Branch, Division of Bacterial Disease, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA, lmcgee@cdc.gov Y1 - 2011/12// PY - 2011 DA - December 2011 SP - 453 EP - 456 PB - Elsevier B.V., Box 882 New York NY 10159 United States VL - 71 IS - 4 SN - 0732-8893, 0732-8893 KW - Microbiology Abstracts B: Bacteriology KW - S. pneumoniae KW - Antibiotic resistance KW - Real-time PCR KW - Streptococcus pneumoniae KW - Polymerase chain reaction KW - Antibiotics KW - Penicillin KW - lincosamides KW - Antimicrobial agents KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/918061396?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Diagnostic+Microbiology+and+Infectious+Disease&rft.atitle=Quadriplex+real-time+polymerase+chain+reaction+%28lytA%2C+mef%2C+erm%2C+pbp2bwt%29+for+pneumococcal+detection+and+assessment+of+antibiotic+susceptibility&rft.au=Srinivasan%2C+Velusamy%3Bdu+Plessis%2C+Mignon%3BBeall%2C+Bernard+W%3BMcGee%2C+Lesley&rft.aulast=Srinivasan&rft.aufirst=Velusamy&rft.date=2011-12-01&rft.volume=71&rft.issue=4&rft.spage=453&rft.isbn=&rft.btitle=&rft.title=Diagnostic+Microbiology+and+Infectious+Disease&rft.issn=07328893&rft_id=info:doi/10.1016%2Fj.diagmicrobio.2011.08.017 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-01-01 N1 - Last updated - 2016-07-07 N1 - SubjectsTermNotLitGenreText - Polymerase chain reaction; Antibiotics; lincosamides; Penicillin; Antimicrobial agents; Streptococcus pneumoniae DO - http://dx.doi.org/10.1016/j.diagmicrobio.2011.08.017 ER - TY - JOUR T1 - Assessment of Differential Item Functioning in the Experiences of Discrimination Index AN - 918048862; 16099515 AB - The psychometric properties of instruments used to measure self-reported experiences of discrimination in epidemiologic studies are rarely assessed, especially regarding construct validity. The authors used 2000-2001 data from the Coronary Artery Risk Development in Young Adults (CARDIA) Study to examine differential item functioning (DIF) in 2 versions of the Experiences of Discrimination (EOD) Index, an index measuring self-reported experiences of racial/ethnic and gender discrimination. DIF may confound interpretation of subgroup differences. Large DIF was observed for 2 of 7 racial/ethnic discrimination items: White participants reported more racial/ethnic discrimination for the "at school" item, and black participants reported more racial/ethnic discrimination for the "getting housing" item. The large DIF by race/ethnicity in the index for racial/ethnic discrimination probably reflects item impact and is the result of valid group differences between blacks and whites regarding their respective experiences of discrimination. The authors also observed large DIF by race/ethnicity for 3 of 7 gender discrimination items. This is more likely to have been due to item bias. Users of the EOD Index must consider the advantages and disadvantages of DIF adjustment (omitting items, constructing separate measures, and retaining items). The EOD Index has substantial usefulness as an instrument that can assess self-reported experiences of discrimination. JF - American Journal of Epidemiology AU - Cunningham, Timothy J AU - Berkman, Lisa F AU - Gortmaker, Steven L AU - Kiefe, Catarina I AU - Jacobs, David R AU - Seeman, Teresa E AU - Kawachi, Ichiro Y1 - 2011/12/01/ PY - 2011 DA - 2011 Dec 01 SP - 1266 EP - 1274 PB - Oxford University Press, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 174 IS - 11 SN - 0002-9262, 0002-9262 KW - Risk Abstracts KW - discrimination KW - Housing KW - schools KW - Gender KW - young adults KW - Ethnic groups KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/918048862?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Epidemiology&rft.atitle=Assessment+of+Differential+Item+Functioning+in+the+Experiences+of+Discrimination+Index&rft.au=Cunningham%2C+Timothy+J%3BBerkman%2C+Lisa+F%3BGortmaker%2C+Steven+L%3BKiefe%2C+Catarina+I%3BJacobs%2C+David+R%3BSeeman%2C+Teresa+E%3BKawachi%2C+Ichiro&rft.aulast=Cunningham&rft.aufirst=Timothy&rft.date=2011-12-01&rft.volume=174&rft.issue=11&rft.spage=1266&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Epidemiology&rft.issn=00029262&rft_id=info:doi/10.1093%2Faje%2Fkwr253 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-01-01 N1 - Last updated - 2013-11-04 N1 - SubjectsTermNotLitGenreText - discrimination; schools; Housing; Gender; young adults; Ethnic groups DO - http://dx.doi.org/10.1093/aje/kwr253 ER - TY - JOUR T1 - Closing the Gap: A Research Agenda to Accelerate the Adoption and Effective Use of Proven Older Adult Fall Prevention Strategies AN - 915492484; 16146379 AB - Introduction: To make an impact on the public's health, evidence-based interventions must be disseminated broadly, supported by training and technical assistance, adopted widely, and implemented as designed. Many effective older adult fall prevention interventions have been identified, but too few have gained wide community acceptance and little is known about the best ways to encourage their broader use. Therefore, as in many other fields, fall prevention suffers from a wide gap between scientific discoveries and their everyday use. Method: This article articulates the key activities embedded in Step 4 of the public health model-specifically translation and dissemination to ensure widespread adoption and use-in order to illuminate critical research needs in older adult fall prevention. Conclusions: These needs, if addressed, will help close the gap between research and practice. JF - Journal of Safety Research AU - Noonan, Rita K AU - Sleet, David A AU - Stevens, Judy A AD - Division of Unintentional Injury Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, RNoonan@cdc.gov Y1 - 2011/12// PY - 2011 DA - Dec 2011 SP - 427 EP - 430 PB - Elsevier B.V., P.O. Box 800 Kidlington Oxford OX5 1DX United Kingdom VL - 42 IS - 6 SN - 0022-4375, 0022-4375 KW - Health & Safety Science Abstracts KW - Training KW - intervention KW - falls KW - technical assistance KW - Public health KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/915492484?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Safety+Research&rft.atitle=Closing+the+Gap%3A+A+Research+Agenda+to+Accelerate+the+Adoption+and+Effective+Use+of+Proven+Older+Adult+Fall+Prevention+Strategies&rft.au=Noonan%2C+Rita+K%3BSleet%2C+David+A%3BStevens%2C+Judy+A&rft.aulast=Noonan&rft.aufirst=Rita&rft.date=2011-12-01&rft.volume=42&rft.issue=6&rft.spage=427&rft.isbn=&rft.btitle=&rft.title=Journal+of+Safety+Research&rft.issn=00224375&rft_id=info:doi/10.1016%2Fj.jsr.2010.12.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-01-01 N1 - Last updated - 2014-07-24 N1 - SubjectsTermNotLitGenreText - Training; intervention; falls; technical assistance; Public health DO - http://dx.doi.org/10.1016/j.jsr.2010.12.002 ER - TY - JOUR T1 - Healthy People 2010 Objectives for Unintentional Injury and Violence Among Adolescents: Trends from the National Youth Risk Behavior Survey, 1999-2009 AN - 911159206; 16073662 AB - In 2000, the USDHHS released Healthy People 2010 (HP2010), a series of disease prevention and health promotion objectives for the nation. Thirty-nine of these objectives were dedicated to injury prevention and six of these objectives related to adolescents, who were tracked through CDC's National Youth Risk Behavior Survey (YRBS). Purpose: This paper uses national YRBS data from 1999 to 2009 to analyze overall and subgroup trends and determine progress toward targets for the following HP2010 objectives: seatbelt use (HP2010 objective 15-19); motorcycle helmet use (15-21); riding with a driver who had been drinking alcohol (26-6); physical fighting (15-38); weapon carrying on school property (15-39); and suicide attempts requiring medical attention (18-2). Methods: The CDC conducted the national YRBS biennially from 1999 to 2009 and used similar three-stage cluster-sample designs to obtain representative samples of high school students in the U.S. This study was conducted in 2010 and used linear and quadratic time variables simultaneously in logistic regression models while controlling for gender, race/ethnicity, and grade to test for secular trends over time. Results: Only two objectives met their HP2010 targets: riding with a driver who had been drinking alcohol (26-6) and physical fighting (15-38). Progress was seen for four additional objectives and within some subgroups. Conclusions: Substantial policy and practice changes must occur if the recently released Healthy People 2020 targets are to be met. School-, community-, and state-level policies and programs may be effective tools to prevent injuries and victimizations. JF - American Journal of Preventive Medicine AU - Olsen, Emily O& AU - PRIME AU - Malley AU - Hertz, Marci Feldman AU - Shults, Ruth A AU - Hamburger, Merle E AU - Lowry, Richard AD - Division of Adolescent and School Health, CDC, Atlanta, Georgia, dgx1@cdc.gov; PRIME Y1 - 2011/12// PY - 2011 DA - Dec 2011 SP - 551 EP - 558 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 41 IS - 6 SN - 0749-3797, 0749-3797 KW - Risk Abstracts KW - Alcohol KW - Injuries KW - USA KW - Weapons KW - schools KW - helmets KW - prevention KW - Adolescents KW - suicide KW - seat belts KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/911159206?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Healthy+People+2010+Objectives+for+Unintentional+Injury+and+Violence+Among+Adolescents%3A+Trends+from+the+National+Youth+Risk+Behavior+Survey%2C+1999-2009&rft.au=Olsen%2C+Emily+O%26amp%3B%3BPRIME%3BMalley%3BHertz%2C+Marci+Feldman%3BShults%2C+Ruth+A%3BHamburger%2C+Merle+E%3BLowry%2C+Richard&rft.aulast=Olsen&rft.aufirst=Emily&rft.date=2011-12-01&rft.volume=41&rft.issue=6&rft.spage=551&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2011.08.011 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-12-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Alcohol; Weapons; schools; Injuries; helmets; prevention; suicide; Adolescents; seat belts; USA DO - http://dx.doi.org/10.1016/j.amepre.2011.08.011 ER - TY - JOUR T1 - Blood Pressure and Cholesterol Screening Prevalence Among U.S. Women of Reproductive Age: Opportunities to Improve Screening AN - 911159166; 16073660 AB - Blood pressure and cholesterol screening among women of reproductive age are important for early disease detection and intervention, and because hypertension and dyslipidemia are associated with adverse pregnancy outcomes. Purpose: The objective of this study was to examine associations of sociodemographic characteristics, cardiovascular disease risk factors, and healthcare access indicators with blood pressure and cholesterol screening among women of reproductive age. Methods: In 2011, prevalence estimates for self-reported blood pressure screening within 2 years and cholesterol screening within 5 years and AORs for screenings were calculated for 4837 women aged 20-44 years, using weighted 2008 National Health Interview Survey data. Results: Overall, recommended blood pressure and cholesterol screening was received by 89.6% and 63.3% women, respectively. Those who were underinsured or uninsured had the lowest screening percentage at 76.6% for blood pressure (95% CI=73.4, 79.6) and 47.6% for cholesterol (95% CI=43.8, 51.5) screening. Suboptimal cholesterol screening prevalence was also found for women who smoke (54.5%, 95% CI=50.8, 58.2); obese women (69.8%, 95% CI=66.3, 73.0); and those with cardiovascular disease (70.3%, 95% CI=63.7, 76.1), prediabetes (73.3%, 95% CI= 64.1, 80.8), or hypertension (81.4%, 95% CI=76.6, 85.4). Conclusions: Most women received blood pressure screening, but many did not receive cholesterol screening. Universal healthcare access may improve screening prevalence. JF - American Journal of Preventive Medicine AU - Robbins, Cheryl L AU - Dietz, Patricia M AU - Bombard, Jennifer M AU - Gibbs, Falicia AU - Ko, Jean Y AU - Valderrama, Amy L AD - Division of Reproductive Health, CDC, Atlanta, Georgia, ggf9@cdc.gov Y1 - 2011/12// PY - 2011 DA - Dec 2011 SP - 588 EP - 595 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 41 IS - 6 SN - 0749-3797, 0749-3797 KW - Health & Safety Science Abstracts; Risk Abstracts KW - Obesity KW - Age KW - blood pressure KW - Intervention KW - Cholesterol KW - cholesterol KW - Blood pressure KW - USA KW - Health care KW - Risk factors KW - hypertension KW - Females KW - Cardiovascular diseases KW - Disease detection KW - disease detection KW - Hypertension KW - H 12000:Epidemiology and Public Health KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/911159166?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Blood+Pressure+and+Cholesterol+Screening+Prevalence+Among+U.S.+Women+of+Reproductive+Age%3A+Opportunities+to+Improve+Screening&rft.au=Robbins%2C+Cheryl+L%3BDietz%2C+Patricia+M%3BBombard%2C+Jennifer+M%3BGibbs%2C+Falicia%3BKo%2C+Jean+Y%3BValderrama%2C+Amy+L&rft.aulast=Robbins&rft.aufirst=Cheryl&rft.date=2011-12-01&rft.volume=41&rft.issue=6&rft.spage=588&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2011.08.010 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-12-01 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - Obesity; Age; blood pressure; Intervention; Cholesterol; cholesterol; Blood pressure; Health care; Risk factors; hypertension; Disease detection; Cardiovascular diseases; Females; disease detection; Hypertension; USA DO - http://dx.doi.org/10.1016/j.amepre.2011.08.010 ER - TY - JOUR T1 - Sufficient Sleep, Physical Activity, and Sedentary Behaviors AN - 911158567; 16073659 AB - Insufficient sleep among adolescents is common and has adverse health and behavior consequences. Understanding associations of physical activity and sedentary behaviors with sleep duration could shed light on ways to promote sufficient sleep. Purpose: The purpose of this study is to determine whether physical activity and sedentary behaviors are associated with sufficient sleep (8 or more hours of sleep on an average school night) among U.S. high school students. Methods: Data were from the 2009 national Youth Risk Behavior Survey and are representative of 9th-12th-grade students nationally (n=14,782). Associations of physical activity and sedentary behaviors with sufficient sleep were determined using logistic regression models controlling for confounders. Data were analyzed in October 2010. Results: Students who engaged in greater than or equal to 60 minutes of physical activity daily during the 7 days before the survey had higher odds of sufficient sleep than those who did not engage in greater than or equal to 60 minutes on any day. There was no association between the number of days students were vigorously active greater than or equal to 20 minutes and sufficient sleep. Compared to their respective referent groups of 0 hours on an average school day, students who watched TV greater than or equal to 4 hours/day had higher odds of sufficient sleep and students who played video or computer games or used a computer for something that was not school work greater than or equal to 2 hours/day had lower odds of sufficient sleep. Conclusions: Daily physical activity for greater than or equal to 60 minutes and limited computer use are associated with sufficient sleep among adolescents. JF - American Journal of Preventive Medicine AU - Foti, Kathryn E AU - Eaton, Danice K AU - Lowry, Richard AU - McKnight-Ely, Lela R AD - Division of Adolescent and School Health, National Center for Chronic Disease Prevention and Health Promotion, CDC, Atlanta, Georgia, htk7@cdc.gov Y1 - 2011/12// PY - 2011 DA - Dec 2011 SP - 596 EP - 602 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 41 IS - 6 SN - 0749-3797, 0749-3797 KW - Physical Education Index; Risk Abstracts KW - High school students KW - USA KW - schools KW - Behavior KW - Sleep KW - Computers KW - Adolescence KW - Health (behavior) KW - Exercise KW - physical activity KW - Adolescents KW - R2 23060:Medical and environmental health KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/911158567?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Sufficient+Sleep%2C+Physical+Activity%2C+and+Sedentary+Behaviors&rft.au=Foti%2C+Kathryn+E%3BEaton%2C+Danice+K%3BLowry%2C+Richard%3BMcKnight-Ely%2C+Lela+R&rft.aulast=Foti&rft.aufirst=Kathryn&rft.date=2011-12-01&rft.volume=41&rft.issue=6&rft.spage=596&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2011.08.009 LA - English DB - Physical Education Index; ProQuest Environmental Science Collection N1 - Date revised - 2011-12-01 N1 - Last updated - 2013-11-15 N1 - SubjectsTermNotLitGenreText - High school students; Adolescence; Computers; Sleep; Health (behavior); Exercise; Behavior; schools; physical activity; Adolescents; USA DO - http://dx.doi.org/10.1016/j.amepre.2011.08.009 ER - TY - JOUR T1 - Influenza A (H1N1) 2009 Monovalent Vaccination Among Adults with Asthma, U.S., 2010 AN - 911156830; 16073653 AB - The 2009 pandemic influenza A (H1N1) virus (2009 H1N1) was first identified in April 2009 and quickly spread around the world. The first doses of influenza A (H1N1) 2009 monovalent vaccine (2009 H1N1 vaccine) became available in the U.S. in early October 2009. Because people with asthma are at increased risk of complications from influenza, people with asthma were included among the initial prioritized groups. Purpose: To evaluate 2009 H1N1 vaccination coverage and identify factors independently associated with vaccination among adults with asthma in the U.S. Methods: Data from the 2009-2010 BRFSS (Behavioral Risk Factor Surveillance System) influenza supplemental survey were used; responses from March through June 2010 were analyzed to estimate vaccination levels of 2009 H1N1 vaccine among respondents aged 25-64 years with asthma. Multivariable logistic regression and predictive marginal models were performed to identify factors independently associated with vaccination. Results: Among adults aged 25-64 years with asthma, 25.5% (95% CI=23.9%, 27.2%) received the 2009 H1N1 vaccination. Vaccination coverage ranged from 9.9% (95% CI=6.4%, 15.1%) in Mississippi to 46.1% (95% CI=33.3%, 61.2%) in Maine. Characteristics independently associated with an increased likelihood of vaccination among adults with asthma were as follows: had a primary doctor, had other high-risk conditions, and received seasonal influenza vaccination in the 2009-2010 season. Conclusions: Vaccination coverage among adults aged 25-64 years with asthma was only 25.5% and varied widely by state and demographic characteristics. National and state-specific 2009 H1N1 vaccination coverage data for adults with asthma are useful for evaluating the vaccination campaign and for planning and implementing strategies for increasing vaccination coverage in possible future pandemics. JF - American Journal of Preventive Medicine AU - Lu, Peng-Jun AU - Callahan, David B AU - Ding, Helen AU - Euler, Gary L AD - Immunization Services Division, National Center for Immunization and Respiratory Diseases, CDC, Atlanta, Georgia, lhp8@cdc.gov Y1 - 2011/12// PY - 2011 DA - Dec 2011 SP - 619 EP - 626 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 41 IS - 6 SN - 0749-3797, 0749-3797 KW - Virology & AIDS Abstracts; Health & Safety Science Abstracts; Risk Abstracts KW - demography KW - vaccines KW - Influenza A KW - Respiratory diseases KW - influenza KW - Models KW - Influenza KW - Demography KW - pandemics KW - Sulfur dioxide KW - Risk factors KW - Regression analysis KW - Risk groups KW - Seasonal variations KW - Data processing KW - Complications KW - Asthma KW - Vaccination KW - complications KW - USA, Mississippi KW - USA, Maine KW - Vaccines KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/911156830?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Influenza+A+%28H1N1%29+2009+Monovalent+Vaccination+Among+Adults+with+Asthma%2C+U.S.%2C+2010&rft.au=Lu%2C+Peng-Jun%3BCallahan%2C+David+B%3BDing%2C+Helen%3BEuler%2C+Gary+L&rft.aulast=Lu&rft.aufirst=Peng-Jun&rft.date=2011-12-01&rft.volume=41&rft.issue=6&rft.spage=619&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2011.08.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-12-01 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - Demography; pandemics; Data processing; Risk factors; Influenza A; Regression analysis; Risk groups; Asthma; Vaccines; Vaccination; Models; demography; vaccines; Complications; Respiratory diseases; influenza; Influenza; Sulfur dioxide; complications; Seasonal variations; USA, Mississippi; USA, Maine DO - http://dx.doi.org/10.1016/j.amepre.2011.08.004 ER - TY - JOUR T1 - Comprehensive assessment of maize aflatoxin levels in Eastern Kenya, 2005-2007. AN - 908009266; 21843999 AB - Aflatoxin, a potent fungal toxin, contaminates 25% of crops worldwide. Since 2004, 477 aflatoxin poisonings associated with eating contaminated maize have been documented in Eastern Kenya, with a case-fatality rate of 40%. We characterized maize aflatoxin contamination during the high-risk season (April-June) after the major harvests in 2005, 2006 (aflatoxicosis outbreak years), and 2007 (a non-outbreak year). Households were randomly selected each year from the region in Kenya where outbreaks have consistently occurred. At each household, we obtained at least one maize sample (n = 716) for aflatoxin analysis using immunoaffinity methods and administered a questionnaire to determine the source (i.e., homegrown, purchased, or relief) and amount of maize in the household. During the years of outbreaks in 2005 and 2006, 41% and 51% of maize samples, respectively, had aflatoxin levels above the Kenyan regulatory limit of 20 ppb in grains that were for human consumption. In 2007 (non-outbreak year), 16% of samples were above the 20-ppb limit. In addition, geometric mean (GM) aflatoxin levels were significantly higher in 2005 (GM = 12.92, maximum = 48,000 ppb) and 2006 (GM = 26.03, maximum = 24,400 ppb) compared with 2007 (GM = 1.95, maximum = 2,500 ppb) (p-value < 0.001). In all 3 years combined, maize aflatoxin levels were significantly higher in homegrown maize (GM = 17.96) when compared with purchased maize (GM = 3.64) or relief maize (GM = 0.73) (p-value < 0.0001). Aflatoxin contamination is extreme within this region, and homegrown maize is the primary source of contamination. Prevention measures should focus on reducing homegrown maize contamination at the household level to avert future outbreaks. JF - Environmental health perspectives AU - Daniel, Johnni H AU - Lewis, Lauren W AU - Redwood, Yanique A AU - Kieszak, Stephanie AU - Breiman, Robert F AU - Flanders, W Dana AU - Bell, Carlos AU - Mwihia, John AU - Ogana, George AU - Likimani, Sopiato AU - Straetemans, Masja AU - McGeehin, Michael A AD - Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA. bez2@cdc.gov Y1 - 2011/12// PY - 2011 DA - December 2011 SP - 1794 EP - 1799 VL - 119 IS - 12 KW - Aflatoxins KW - 0 KW - Index Medicus KW - Family Characteristics KW - Cross-Sectional Studies KW - Humans KW - Surveys and Questionnaires KW - Fluorometry KW - Limit of Detection KW - Kenya -- epidemiology KW - Aflatoxins -- poisoning KW - Aflatoxins -- analysis KW - Zea mays -- microbiology KW - Foodborne Diseases -- epidemiology KW - Zea mays -- chemistry KW - Food Contamination -- statistics & numerical data KW - Food Contamination -- analysis KW - Aspergillus -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/908009266?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+health+perspectives&rft.atitle=Comprehensive+assessment+of+maize+aflatoxin+levels+in+Eastern+Kenya%2C+2005-2007.&rft.au=Daniel%2C+Johnni+H%3BLewis%2C+Lauren+W%3BRedwood%2C+Yanique+A%3BKieszak%2C+Stephanie%3BBreiman%2C+Robert+F%3BFlanders%2C+W+Dana%3BBell%2C+Carlos%3BMwihia%2C+John%3BOgana%2C+George%3BLikimani%2C+Sopiato%3BStraetemans%2C+Masja%3BMcGeehin%2C+Michael+A&rft.aulast=Daniel&rft.aufirst=Johnni&rft.date=2011-12-01&rft.volume=119&rft.issue=12&rft.spage=1794&rft.isbn=&rft.btitle=&rft.title=Environmental+health+perspectives&rft.issn=1552-9924&rft_id=info:doi/10.1289%2Fehp.1003044 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-03-27 N1 - Date created - 2011-12-02 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Environ Health Perspect. 2005 Dec;113(12):1779-83 [16330363] Environ Health Perspect. 2005 Dec;113(12):1763-7 [16330360] Food Nutr Bull. 2007 Jun;28(2 Suppl):S372-80 [17658084] Anal Bioanal Chem. 2007 Sep;389(1):147-57 [17508207] Food Addit Contam. 2007 Nov;24(11):1283-91 [17852397] Clin Dev Immunol. 2008;2008:790309 [18695741] East Afr Med J. 2008 Jul;85(7):311-7 [19133419] Cancer Lett. 2009 Dec 1;286(1):22-8 [19345001] Carcinogenesis. 2010 Jan;31(1):71-82 [19875698] MMWR Morb Mortal Wkly Rep. 2004 Sep 3;53(34):790-3 [15343146] Am J Trop Med Hyg. 1981 Mar;30(2):422-5 [7015891] Lancet. 1982 Jun 12;1(8285):1346-8 [6123648] World Health Stat Q. 1985;38(1):65-75 [4002731] Am J Clin Nutr. 2004 Nov;80(5):1106-22 [15531656] Appl Environ Microbiol. 2007 Apr;73(8):2762-4 [17308181] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1289/ehp.1003044 ER - TY - JOUR T1 - Have Secular Changes in Perinatal Risk Factors Contributed to the Recent Autism Prevalence Increase? Development and Application of a Mathematical Assessment Model AN - 907176318; 16051402 AB - A 57% increase in the U.S. prevalence of autism spectrum disorders (ASD) for 8-year-old children born in 1994 versus 1998 was recently reported. Methods: To quantify the possible contributions of given risk/predictive factors on the recent ASD prevalence increase, we formulated a mathematical model based on the baseline risk factor prevalence (RFP), the proportionate change in RFP (cRFP), and the magnitude of the association between the risk factor and ASD [estimated relative risk (RR)]. We applied this model to several pregnancy-related factors (preterm, very preterm, low and very low birth weight, multiple birth, cesarean delivery, breech presentation, and assisted reproductive technology use). RFP and cRFP estimates for each factor were obtained from U.S. population-based surveillance datasets. Estimated RRs were obtained from a series of systematic literature reviews. Results: We estimate that each risk factor examined, alone or in various combinations, accounted for a very small proportion (<1%) of the ASD increase. Additionally, hypothetical scenarios indicate RFP, cRFP, and RR all need to be sizable for a risk factor to appreciably influence ASD prevalence. Conclusions: Thus, although various pregnancy factors have been found to be associated with ASDs, the contribution of many of these factors to the recently observed ASD increase is likely minimal. JF - Annals of Epidemiology AU - Schieve, Laura A AU - Rice, Catherine AU - Devine, Owen AU - Maenner, Matthew J AU - Lee, Li-Ching AU - Fitzgerald, Robert AU - Wingate, Martha S AU - Schendel, Diana AU - Pettygrove, Sydney AU - Van, Kim AU - Durkin, Maureen AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA, LSchieve@cdc.gov Y1 - 2011/12// PY - 2011 DA - Dec 2011 SP - 930 EP - 945 PB - Elsevier B.V., Box 882 New York NY 10159 United States VL - 21 IS - 12 SN - 1047-2797, 1047-2797 KW - Risk Abstracts KW - Children KW - Mathematical models KW - Pregnancy KW - Reviews KW - Risk factors KW - low-birth-weight KW - reproductive technology KW - USA UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/907176318?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annals+of+Epidemiology&rft.atitle=Have+Secular+Changes+in+Perinatal+Risk+Factors+Contributed+to+the+Recent+Autism+Prevalence+Increase%3F+Development+and+Application+of+a+Mathematical+Assessment+Model&rft.au=Schieve%2C+Laura+A%3BRice%2C+Catherine%3BDevine%2C+Owen%3BMaenner%2C+Matthew+J%3BLee%2C+Li-Ching%3BFitzgerald%2C+Robert%3BWingate%2C+Martha+S%3BSchendel%2C+Diana%3BPettygrove%2C+Sydney%3BVan%2C+Kim%3BDurkin%2C+Maureen&rft.aulast=Schieve&rft.aufirst=Laura&rft.date=2011-12-01&rft.volume=21&rft.issue=12&rft.spage=930&rft.isbn=&rft.btitle=&rft.title=Annals+of+Epidemiology&rft.issn=10472797&rft_id=info:doi/10.1016%2Fj.annepidem.2011.08.009 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2012-09-24 N1 - SubjectsTermNotLitGenreText - reproductive technology; Mathematical models; Reviews; Risk factors; low-birth-weight; Children; Pregnancy; USA DO - http://dx.doi.org/10.1016/j.annepidem.2011.08.009 ER - TY - JOUR T1 - Rift Valley fever virus vaccine lacking the NSs and NSm genes is safe, nonteratogenic, and confers protection from viremia, pyrexia, and abortion following challenge in adult and pregnant sheep. AN - 905873464; 21976656 AB - Rift Valley fever virus (RVFV) is a mosquito-borne human and veterinary pathogen causing large outbreaks of severe disease throughout Africa and the Arabian Peninsula. Safe and effective vaccines are critically needed, especially those that can be used in a targeted one-health approach to prevent both livestock and human disease. We report here on the safety, immunogenicity, and efficacy of the ΔNSs-ΔNSm recombinant RVFV (rRVFV) vaccine (which lacks the NSs and NSm virulence factors) in a total of 41 sheep, including 29 timed-pregnant ewes. This vaccine was proven safe and immunogenic for adult animals at doses ranging from 1.0 × 10(3) to 1.0 × 10(5) PFU administered subcutaneously (s.c.). Pregnant animals were vaccinated with 1.0 × 10(4) PFU s.c. at day 42 of gestation, when fetal sensitivity to RVFV vaccine-induced teratogenesis is highest. No febrile reactions, clinical illness, or pregnancy loss was observed following vaccination. Vaccination resulted in a rapid increase in anti-RVFV IgM (day 4) and IgG (day 7) titers. No seroconversion occurred in cohoused control animals. A subset of 20 ewes progressed to full-term delivery after vaccination. All lambs were born without musculoskeletal, neurological, or histological birth defects. Vaccine efficacy was assessed in 9 pregnant animals challenged at day 122 of gestation with virulent RVFV (1.0 × 10(6) PFU intravenously). Following challenge, 100% (9/9) of the animals were protected, progressed to full term, and delivered healthy lambs. As expected, all 3 sham-vaccinated controls experienced viremia, fetal death, and abortion postchallenge. These results demonstrate that the ΔNSs-ΔNSm rRVFV vaccine is safe and nonteratogenic and confers high-level protection in sheep. JF - Journal of virology AU - Bird, Brian H AU - Maartens, Louis H AU - Campbell, Shelley AU - Erasmus, Baltus J AU - Erickson, Bobbie R AU - Dodd, Kimberly A AU - Spiropoulou, Christina F AU - Cannon, Deborah AU - Drew, Clifton P AU - Knust, Barbara AU - McElroy, Anita K AU - Khristova, Marina L AU - Albariño, César G AU - Nichol, Stuart T AD - Viral Special Pathogens Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, 1600 Clifton Road, MS G-14, Atlanta, GA 30329, USA. Y1 - 2011/12// PY - 2011 DA - December 2011 SP - 12901 EP - 12909 VL - 85 IS - 24 KW - Vaccines, Attenuated KW - 0 KW - Vaccines, Synthetic KW - Viral Nonstructural Proteins KW - Viral Vaccines KW - Index Medicus KW - Viremia -- prevention & control KW - Animals KW - Congenital Abnormalities -- veterinary KW - Vaccines, Attenuated -- administration & dosage KW - Congenital Abnormalities -- prevention & control KW - Humans KW - Sheep KW - Gene Deletion KW - Pregnancy KW - Viral Nonstructural Proteins -- genetics KW - Fever -- prevention & control KW - Fever -- veterinary KW - Vaccines, Synthetic -- immunology KW - Vaccines, Attenuated -- immunology KW - Vaccines, Attenuated -- genetics KW - Injections, Subcutaneous KW - Vaccines, Synthetic -- administration & dosage KW - Vaccines, Synthetic -- genetics KW - Viremia -- veterinary KW - Vaccines, Synthetic -- adverse effects KW - Vaccines, Attenuated -- adverse effects KW - Female KW - Viral Vaccines -- administration & dosage KW - Sheep Diseases -- immunology KW - Rift Valley Fever -- prevention & control KW - Viral Vaccines -- adverse effects KW - Viral Vaccines -- genetics KW - Sheep Diseases -- prevention & control KW - Rift Valley fever virus -- genetics KW - Viral Vaccines -- immunology KW - Rift Valley fever virus -- immunology KW - Rift Valley Fever -- veterinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/905873464?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+virology&rft.atitle=Rift+Valley+fever+virus+vaccine+lacking+the+NSs+and+NSm+genes+is+safe%2C+nonteratogenic%2C+and+confers+protection+from+viremia%2C+pyrexia%2C+and+abortion+following+challenge+in+adult+and+pregnant+sheep.&rft.au=Bird%2C+Brian+H%3BMaartens%2C+Louis+H%3BCampbell%2C+Shelley%3BErasmus%2C+Baltus+J%3BErickson%2C+Bobbie+R%3BDodd%2C+Kimberly+A%3BSpiropoulou%2C+Christina+F%3BCannon%2C+Deborah%3BDrew%2C+Clifton+P%3BKnust%2C+Barbara%3BMcElroy%2C+Anita+K%3BKhristova%2C+Marina+L%3BAlbari%C3%B1o%2C+C%C3%A9sar+G%3BNichol%2C+Stuart+T&rft.aulast=Bird&rft.aufirst=Brian&rft.date=2011-12-01&rft.volume=85&rft.issue=24&rft.spage=12901&rft.isbn=&rft.btitle=&rft.title=Journal+of+virology&rft.issn=1098-5514&rft_id=info:doi/10.1128%2FJVI.06046-11 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-01-23 N1 - Date created - 2011-11-22 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: J Am Vet Med Assoc. 2009 Apr 1;234(7):883-93 [19335238] PLoS Pathog. 2009 Feb;5(2):e1000287 [19197350] Virol J. 2009;6:125 [19678951] J Virol. 2010 Jan;84(2):928-39 [19889787] Am J Trop Med Hyg. 2010 Aug;83(2 Suppl):58-64 [20682907] Vet Res. 2010 Nov-Dec;41(6):61 [21188836] J Virol. 2011 Jul;85(13):6162-7 [21507967] Am J Trop Med Hyg. 2010 Aug;83(2 Suppl):14-21 [20682901] J Virol. 2000 Feb;74(3):1538-43 [10627566] J Virol. 2001 Feb;75(3):1371-7 [11152510] Onderstepoort J Vet Res. 2002 Mar;69(1):95-8 [12092782] Clin Infect Dis. 2003 Oct 15;37(8):1084-92 [14523773] Cell. 2004 Feb 20;116(4):541-50 [14980221] Am J Trop Med Hyg. 2010 Mar;82(3):371-5 [20207858] Vaccine. 2010 Jun 23;28(29):4581-7 [20470792] J Virol. 2004 Sep;78(18):9798-806 [15331713] Onderstepoort J Vet Res. 1977 Dec;44(4):205-11 [613292] Am J Vet Res. 1980 Oct;41(10):1559-64 [7224281] Virology. 1981 Jun;111(2):662-5 [7245612] Onderstepoort J Vet Res. 1982 Mar;49(1):11-7 [7122060] Am J Trop Med Hyg. 1995 Oct;53(4):405-11 [7485695] J Virol. 1999 Oct;73(10):8196-200 [10482570] J Med Virol. 2006 Jun;78(6):787-91 [16628582] J Virol. 2006 Aug;80(16):8274-8 [16873285] J Virol. 2007 Mar;81(6):2805-16 [17192303] Virology. 2007 Mar 15;359(2):459-65 [17070883] Virology. 2007 May 25;362(1):10-5 [17412386] J Clin Microbiol. 2007 Nov;45(11):3506-13 [17804663] J Virol. 2007 Dec;81(24):13335-45 [17913816] Br J Exp Pathol. 1949 Feb;30(1):1-16 [18128091] J Virol. 2008 Mar;82(6):2681-91 [18199647] J Virol. 2008 Nov;82(22):11152-66 [18786992] J Virol. 2009 May;83(9):4365-75 [19211744] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1128/JVI.06046-11 ER - TY - JOUR T1 - Psychopathy, reactive aggression, and precarious proclamations: A review of behavioral, cognitive, and biological research AN - 902366854; 15912079 AB - Psychopathic personality (psychopathy) is associated with a heightened risk for physical aggression, although the nature of this link remains unclear. Despite widespread claims that psychopathy is associated with reactive aggression, the evidence for this assertion is mixed. We provide a comprehensive review of behavioral, cognitive, and biological research on the relation between psychopathy and aggression, and conclude that although psychopathy is clearly associated with instrumental aggression, its association with reactive aggression is not robust. In fact, at least some research points to a potential protective role of psychopathy against reactive aggression. We conclude that future research must clarify the differential implications of the separable components of the broad psychopathy construct before the relations between psychopathy and physical aggression can be adequately understood. JF - Aggression and Violent Behavior AU - Reidy, Dennis E AU - Shelley-Tremblay, John F AU - Lilienfeld, Scott O AD - Centers for Disease Control & Prevention, Division of Violence Prevention, United States, dreidy@cdc.gov Y1 - 2011/12// PY - 2011 DA - Dec 2011 SP - 512 EP - 524 PB - Elsevier B.V., P.O. Box 800 Kidlington Oxford OX5 1DX United Kingdom VL - 16 IS - 6 SN - 1359-1789, 1359-1789 KW - Risk Abstracts KW - Reviews KW - aggressive behavior KW - personality KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/902366854?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aggression+and+Violent+Behavior&rft.atitle=Psychopathy%2C+reactive+aggression%2C+and+precarious+proclamations%3A+A+review+of+behavioral%2C+cognitive%2C+and+biological+research&rft.au=Reidy%2C+Dennis+E%3BShelley-Tremblay%2C+John+F%3BLilienfeld%2C+Scott+O&rft.aulast=Reidy&rft.aufirst=Dennis&rft.date=2011-12-01&rft.volume=16&rft.issue=6&rft.spage=512&rft.isbn=&rft.btitle=&rft.title=Aggression+and+Violent+Behavior&rft.issn=13591789&rft_id=info:doi/10.1016%2Fj.avb.2011.06.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Reviews; personality; aggressive behavior DO - http://dx.doi.org/10.1016/j.avb.2011.06.002 ER - TY - JOUR T1 - Sickle Cell Disease: The Need for a Public Health Agenda AN - 1221424278; 2011-331776 AB - Sickle cell disease (SCD) is a collection of inherited blood disorders that affect a substantial number of people in the U.S., particularly African Americans. People with SCD have an abnormal type of hemoglobin, Hb S, which polymerizes when deoxygenated, causing the red blood cells to become misshapen and rigid. Individuals with SCD are at higher risk of morbidity and mortality from infections, vaso-occlusive pain crises, acute chest syndrome, and other complications. Addressing the public health needs related to SCD is an important step toward improving outcomes and maintaining health for those affected by the disorder. The objective of this study was to review public health activities focusing on SCD and define the need to address it more comprehensively from a public health perspective. We found that there has been some progress in the development of SCD-related public health activities. Such activities include establishing newborn screening (NBS) for SCD with all states currently having universal NBS programs. However, additional areas needing focus include strengthening surveillance and monitoring of disease occurrence and health outcomes, enhancing adherence to health maintenance guidelines, increasing knowledge and awareness among those affected, and improving healthcare access and utilization. These and other activities discussed in this paper can help strengthen public health efforts to address SCD. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Yusuf, Hussain R AU - Lloyd-Puryear, Michele A AU - Grant, Althea M AU - Parker, Christopher S AU - Creary, Melissa S AU - Atrash, Hani K AD - Division of Blood Disorders, National Center on Birth Defects and Developmental Disabilities, CDC, 1600 Clifton Road NE, MS-E64, Atlanta GA 30333 hyusuf@cdc.gov Y1 - 2011/12// PY - 2011 DA - December 2011 SP - S376 EP - S383 PB - Elsevier Science, New York NY VL - 41 IS - 6 SN - 0749-3797, 0749-3797 KW - Health conditions and policy - Diseases and disorders KW - Health conditions and policy - Health and health policy KW - Population groups, population policy, and demographics - National, ethnic, and minority groups KW - Population groups, population policy, and demographics - Demography and census KW - Mortality KW - Blacks KW - Health policy KW - Diseases KW - Sickle cell anemia KW - Public health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1221424278?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Sickle+Cell+Disease%3A+The+Need+for+a+Public+Health+Agenda&rft.au=Yusuf%2C+Hussain+R%3BLloyd-Puryear%2C+Michele+A%3BGrant%2C+Althea+M%3BParker%2C+Christopher+S%3BCreary%2C+Melissa+S%3BAtrash%2C+Hani+K&rft.aulast=Yusuf&rft.aufirst=Hussain&rft.date=2011-12-01&rft.volume=41&rft.issue=6&rft.spage=S376&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2011.09.007 LA - English DB - PAIS Index N1 - Date revised - 2012-12-01 N1 - Last updated - 2016-09-28 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Sickle cell anemia; Public health; Diseases; Blacks; Health policy; Mortality DO - http://dx.doi.org/10.1016/j.amepre.2011.09.007 ER - TY - JOUR T1 - Disability Among Individuals with Sickle Cell Disease: Literature Review from a Public Health Perspective AN - 1125284736; 201227624 AB - Context: Young people with blood disorders face challenges in maintaining their physical health as they age. Sickle cell disease has well-documented complications in various organ systems. Increasingly, professionals, consumers, and advocates involved in blood disorders are concerned about the cumulative and ongoing effect of organ-specific complications on function and participation. Evidence acquisition: Publications were identified that looked at the relationship between sickle cell disease and associated impairments and restrictions in participation as defined by the International Classification of Function, Disability, and Health (ICF). Evidence synthesis: This article organizes a literature review in PubMed using ICF terms that define functional limitations and participation restrictions in sickle cell disease. Conclusions: Individuals with sickle cell disease experience complications in multiple organ systems that affect related functions and, consequently, participation in community living. The effects begin early in childhood and accumulate across the life course into adulthood. Intervention research is needed to understand how contextual factors can promote optimal function and participation in the face of mounting impairments. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Swanson, Mark E AU - Grosse, Scott D AU - Kulkarni, Roshni AD - Division of Human Development and Disability, National Center on Birth Defects and Developmental Disabilities, CDC, 1600 Clifton Road NE, MS E-87, Atlanta GA 30333 meswanson@cdc.gov Y1 - 2011/12// PY - 2011 DA - December 2011 SP - S390 EP - S397 PB - Elsevier Science, New York NY VL - 41 IS - 6 SN - 0749-3797, 0749-3797 KW - Advocacy services KW - Health KW - Disability KW - Sickle cell anaemia KW - Blood disorders KW - Biological organs KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1125284736?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Disability+Among+Individuals+with+Sickle+Cell+Disease%3A+Literature+Review+from+a+Public+Health+Perspective&rft.au=Swanson%2C+Mark+E%3BGrosse%2C+Scott+D%3BKulkarni%2C+Roshni&rft.aulast=Swanson&rft.aufirst=Mark&rft.date=2011-12-01&rft.volume=41&rft.issue=6&rft.spage=S390&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2011.09.006 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2012-11-01 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Sickle cell anaemia; Biological organs; Blood disorders; Disability; Advocacy services; Health DO - http://dx.doi.org/10.1016/j.amepre.2011.09.006 ER - TY - JOUR T1 - Iron Overload: What Is the Role of Public Health? AN - 1125284706; 201226502 AB - Hereditary hemochromatosis type 1, also known as hereditary hemochromatosis classical (HHC), is an iron overload disorder associated, in most cases, with mutations of the hemochromatosis (HFE) gene. Although suggested algorithms for diagnosing iron overload are available, there are still questions about options for genetic and biochemical screening for hemochromatosis and duration of treatment. This article provides a summary of an expert workgroup meeting convened on September 24-25, 2009, entitled "Iron Overload: What is the Role of Public Health?" The purpose of the meeting was to enable subject matter experts to share their most recent clinical and scientific iron overload information and to facilitate the discussion of future endeavors, with special emphasis on the role of public health in this field. The two main topics were the research priorities of the field, including clinical, genetic, and public health issues, and the concerns about the validity of current screening recommendations for the condition. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Hulihan, Mary M AU - Sayers, Cindy A AU - Grosse, Scott D AU - Garrison, Cheryl AU - Grant, Althea M AD - Division of Blood Disorders, National Center on Birth Defects and Developmental Disabilities, CDC, 1600 Clifton Road, NE MS- E64, Atlanta GA 30333 mhulihan@cdc.gov Y1 - 2011/12// PY - 2011 DA - December 2011 SP - S422 EP - S427 PB - Elsevier Science, New York NY VL - 41 IS - 6 SN - 0749-3797, 0749-3797 KW - Screening KW - Genes KW - Medical research KW - Haemochromatosis KW - Algorithms KW - Public health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1125284706?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Iron+Overload%3A+What+Is+the+Role+of+Public+Health%3F&rft.au=Hulihan%2C+Mary+M%3BSayers%2C+Cindy+A%3BGrosse%2C+Scott+D%3BGarrison%2C+Cheryl%3BGrant%2C+Althea+M&rft.aulast=Hulihan&rft.aufirst=Mary&rft.date=2011-12-01&rft.volume=41&rft.issue=6&rft.spage=S422&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2011.09.020 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2012-11-01 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Haemochromatosis; Public health; Screening; Genes; Algorithms; Medical research DO - http://dx.doi.org/10.1016/j.amepre.2011.09.020 ER - TY - JOUR T1 - Developing Public Health Surveillance for Deep Vein Thrombosis and Pulmonary Embolism AN - 1125283814; 201225601 AB - Deep vein thrombosis (DVT) and pulmonary embolism (PE), collectively known as venous thromboembolism (VTE), are an important and growing public health issue, associated with considerable morbidity and mortality. Presently, there is no national surveillance for DVT and PE. This article provides a summary of an expert workgroup meeting convened January 12, 2010, by the CDC. The purpose of the meeting was to inform CDC on the development of U.S. population-based public health surveillance activities for DVT/PE. Topics discussed included: (1) stakeholders, needs, gaps, and target populations; (2) requirements of surveillance systems; (3) challenges, limitations, and potential barriers to implementation of surveillance activities; and (4) integration of research and education with surveillance activities. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Beckman, Michele G AU - Grosse, Scott D AU - Kenney, Kristy M AU - Grant, Althea M AU - Atrash, Hani K AD - Division of Blood Disorders, National Center on Birth Defects and Developmental Disabilities, CDC, 1600 Clifton Road, NE, MS-E64, Atlanta GA 30333 mbeckman@cdc.gov Y1 - 2011/12// PY - 2011 DA - December 2011 SP - S428 EP - S434 PB - Elsevier Science, New York NY VL - 41 IS - 6 SN - 0749-3797, 0749-3797 KW - Deep vein thrombosis KW - Stakeholders KW - Pulmonary embolism KW - Surveillance KW - Morbidity-Mortality KW - Public health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1125283814?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Developing+Public+Health+Surveillance+for+Deep+Vein+Thrombosis+and+Pulmonary+Embolism&rft.au=Beckman%2C+Michele+G%3BGrosse%2C+Scott+D%3BKenney%2C+Kristy+M%3BGrant%2C+Althea+M%3BAtrash%2C+Hani+K&rft.aulast=Beckman&rft.aufirst=Michele&rft.date=2011-12-01&rft.volume=41&rft.issue=6&rft.spage=S428&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2011.09.011 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2012-11-01 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Surveillance; Public health; Pulmonary embolism; Morbidity-Mortality; Deep vein thrombosis; Stakeholders DO - http://dx.doi.org/10.1016/j.amepre.2011.09.011 ER - TY - JOUR T1 - Sickle Cell Disease in Africa: A Neglected Cause of Early Childhood Mortality AN - 1125283040; 201227137 AB - Sickle cell disease (SCD) is common throughout much of sub-Saharan Africa, affecting up to 3% of births in some parts of the continent. Nevertheless, it remains a low priority for many health ministries. The most common form of SCD is caused by homozygosity for the beta-globin S gene mutation (SS disease). It is widely believed that this condition is associated with very high child mortality, but reliable contemporary data are lacking. We have reviewed available African data on mortality associated with SS disease from published and unpublished sources, with an emphasis on two types of studies: cross-sectional population surveys and cohort studies. We have concluded that, although current data are inadequate to support definitive statements, they are consistent with an early-life mortality of 50%-90% among children born in Africa with SS disease. Inclusion of SCD interventions in child survival policies and programs in Africa could benefit from more precise estimates of numbers of deaths among children with SCD. A simple, representative, and affordable approach to estimate SCD child mortality is to test blood specimens already collected through large population surveys targeting conditions such as HIV, malaria, and malnutrition, and covering children of varying ages. Thus, although there is enough evidence to justify investments in screening, prophylaxis, and treatment for African children with SCD, better data are needed to estimate the numbers of child deaths preventable by such interventions and their cost effectiveness. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Odame, Isaac AU - Atrash, Hani K AU - Amendah, Djesika D AU - Piel, Frederic B AU - Williams, Thomas N AD - Division of Blood Disorders, National Center on Birth Defects and Developmental Disabilities, CDC, 1600 Clifton Road NE, Mail Stop E-64, Atlanta GA 30333 Y1 - 2011/12// PY - 2011 DA - December 2011 SP - S398 EP - S405 PB - Elsevier Science, New York NY VL - 41 IS - 6 SN - 0749-3797, 0749-3797 KW - Mortality KW - Child mortality KW - Interventions KW - Africa KW - Sickle cell anaemia KW - Children KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1125283040?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Sickle+Cell+Disease+in+Africa%3A+A+Neglected+Cause+of+Early+Childhood+Mortality&rft.au=Odame%2C+Isaac%3BAtrash%2C+Hani+K%3BAmendah%2C+Djesika+D%3BPiel%2C+Frederic+B%3BWilliams%2C+Thomas+N&rft.aulast=Odame&rft.aufirst=Isaac&rft.date=2011-12-01&rft.volume=41&rft.issue=6&rft.spage=S398&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2011.09.013 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2012-11-01 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Children; Mortality; Africa; Interventions; Child mortality; Sickle cell anaemia DO - http://dx.doi.org/10.1016/j.amepre.2011.09.013 ER - TY - JOUR T1 - Public Health Implications of Sickle Cell Trait: A Report of the CDC Meeting AN - 1125283024; 201226309 AB - Although the issue of whether sickle cell trait (SCT) is clinically benign or a significant health concern has not yet been resolved, the potential health risk to affected individuals is of vital importance and represents a tremendous challenge in protecting, promoting, and improving the health of the approximately 300 million people worldwide and 3 million people in the U.S. who possess the trait. In response to a request by the Sickle Cell Disease Association of America, in December 2009, the CDC convened a meeting of partners, stakeholders, and experts to identify the gaps in public health, clinical health services, epidemiologic research, and community-based outreach strategies and to develop an agenda for future initiatives. Through facilitated discussion and presentations in four topic areas, participants discussed pertinent issues, synthesized clinical research findings, and developed a coherent framework for establishing an agenda for future initiatives. A primary outcome of the meeting was to provide the first step of an iterative process to move toward agreement regarding appropriate counseling, care, and, potentially, treatment of people with SCT. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Grant, Althea M AU - Parker, Christopher S AU - Jordan, Lanetta B AU - Hulihan, Mary M AU - Creary, Melissa S AU - Lloyd-Puryear, Michele A AU - Goldsmith, Jonathan C AU - Atrash, Hani K AD - Branch Chief, Epidemiology and Surveillance Branch, Division of Blood Disorders, National Center on Birth Defects and Developmental Disabilities, CDC, 1600 Clifton Road, NE, MS-E64, Atlanta GA 30333 agrant@cdc.gov Y1 - 2011/12// PY - 2011 DA - December 2011 SP - S435 EP - S439 PB - Elsevier Science, New York NY VL - 41 IS - 6 SN - 0749-3797, 0749-3797 KW - Stakeholders KW - Health initiatives KW - Sickle cell anaemia KW - Health services KW - Health promotion KW - Public health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1125283024?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Public+Health+Implications+of+Sickle+Cell+Trait%3A+A+Report+of+the+CDC+Meeting&rft.au=Grant%2C+Althea+M%3BParker%2C+Christopher+S%3BJordan%2C+Lanetta+B%3BHulihan%2C+Mary+M%3BCreary%2C+Melissa+S%3BLloyd-Puryear%2C+Michele+A%3BGoldsmith%2C+Jonathan+C%3BAtrash%2C+Hani+K&rft.aulast=Grant&rft.aufirst=Althea&rft.date=2011-12-01&rft.volume=41&rft.issue=6&rft.spage=S435&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2011.09.012 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2012-11-01 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Public health; Health initiatives; Health services; Sickle cell anaemia; Health promotion; Stakeholders DO - http://dx.doi.org/10.1016/j.amepre.2011.09.012 ER - TY - JOUR T1 - Adverse events after Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis (Tdap) Vaccine administered to adults 65 years of age and older reported to the Vaccine Adverse Event Reporting System (VAERS), 2005-2010 AN - 907184547; 16049619 AB - Background: Tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine was not licensed for use in adults aged greater than or equal to 65 years due to lack of sufficient efficacy and safety data. Objective: To characterize reports to the Vaccine Adverse Event Reporting System (VAERS) among adults aged greater than or equal to 65 years who received Tdap vaccine 'off-label' to assess for potential vaccine safety concerns. Methods: We searched VAERS for US reports of adverse events (AEs) in subjects aged greater than or equal to 65 years who received Tdap vaccine from 9/1/2005 to 9/08/2010. Medical records were requested for all reports coded as serious (death, hospitalization, prolonged hospitalization, permanent disability, life-threatening-illness). Proportional reporting ratio (PRR) was used to assess for higher proportionate reporting for AEs after Tdap compared with Td reports in subjects aged greater than or equal to 65 years. Results: VAERS received 243 reports following Tdap administered to persons aged greater than or equal to 65 years. Eleven (4.5%) reports were serious, including two deaths. Most common AEs were local reactions in 100 (41.2%) reports. Seventy-eight (32.1%) reports contained coding terms that denoted inappropriate administration of vaccine. 'Cough' was the only term associated with disproportionately higher reporting after Tdap compared with Td. Six of seven Tdap reports containing the term 'Cough' were non-serious. Clinical review of serious reports identified no unusual patterns of AEs. Conclusion: Our VAERS review of the 'off-label' use of Tdap vaccine in adults greater than or equal to 65 years did not find any safety concerns that warrant further study. These data will provide useful baseline information to assist CDC and FDA with monitoring efforts as permissive recommendations for Tdap in older persons are adopted. JF - Vaccine AU - Moro, Pedro L AU - Yue, Xin AU - Lewis, Paige AU - Haber, Penina AU - Broder, Karen AD - Immunization Safety Office, Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), Centers for Disease Control and Prevention (CDC), Atlanta, GA 30333, United States, psm9@cdc.gov Y1 - 2011/11/21/ PY - 2011 DA - 2011 Nov 21 SP - 9404 EP - 9408 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 29 IS - 50 SN - 0264-410X, 0264-410X KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Pertussis KW - Data processing KW - medical records KW - Reviews KW - Geriatrics KW - Cough KW - Vaccines KW - Toxoids KW - Diphtheria KW - Tetanus KW - F 06905:Vaccines KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/907184547?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Adverse+events+after+Tetanus+Toxoid%2C+Reduced+Diphtheria+Toxoid+and+Acellular+Pertussis+%28Tdap%29+Vaccine+administered+to+adults+65+years+of+age+and+older+reported+to+the+Vaccine+Adverse+Event+Reporting+System+%28VAERS%29%2C+2005-2010&rft.au=Moro%2C+Pedro+L%3BYue%2C+Xin%3BLewis%2C+Paige%3BHaber%2C+Penina%3BBroder%2C+Karen&rft.aulast=Moro&rft.aufirst=Pedro&rft.date=2011-11-21&rft.volume=29&rft.issue=50&rft.spage=9404&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/10.1016%2Fj.vaccine.2011.05.100 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Pertussis; Data processing; medical records; Reviews; Geriatrics; Cough; Diphtheria; Toxoids; Vaccines; Tetanus DO - http://dx.doi.org/10.1016/j.vaccine.2011.05.100 ER - TY - JOUR T1 - Prepregnancy Body Mass Index and Gestational Weight Gain in Relation to Child Body Mass Index Among Siblings AN - 918062831; 16099503 AB - There is increasing evidence that in utero effects of excessive gestational weight gain may result in increased weight in children; however, studies have not controlled for shared genetic or environmental factors between mothers and children. Using 2,758 family groups from the Collaborative Perinatal Project, the authors examined the association of maternal prepregnancy body mass index (BMI) and gestational weight gain on child BMI at age 4 years using both conventional generalized estimating equations and fixed-effects models that account for shared familial factors. With generalized estimating equations, prepregnancy BMI and gestational weight gain had similar associations with the child BMI z score ( beta = 0.09 units, 95% confidence interval (CI): 0.08, 0.11; and beta = 0.07 units, 95% CI: 0.04, 0.11, respectively. However, fixed effects resulted in null associations for both prepregnancy BMI ( beta = 0.03 units, 95% CI: -0.01, 0.07) and gestational weight gain ( beta = 0.03 units, 95% CI: -0.02, 0.08) with child BMI z score at age 4 years. The positive association between gestational weight gain and child BMI at age 4 years may be explained by shared family characteristics (e.g., genetic, behavioral, and environmental factors) rather than in utero programming. Future studies should continue to evaluate the relative roles of important familial and environmental factors that may influence BMI and obesity in children. JF - American Journal of Epidemiology AU - Branum, Amy M AU - Parker, Jennifer D AU - Keim, Sarah A AU - Schempf, Ashley H Y1 - 2011/11/15/ PY - 2011 DA - 2011 Nov 15 SP - 1159 EP - 1165 PB - Oxford University Press, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 174 IS - 10 SN - 0002-9262, 0002-9262 KW - Physical Education Index; Health & Safety Science Abstracts KW - environmental factors KW - Obesity KW - Age KW - Programs KW - Body mass KW - obesity KW - siblings KW - Children KW - Genetics KW - Weight KW - Epidemiology KW - body mass KW - Family KW - body weight KW - H 12000:Epidemiology and Public Health KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/918062831?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Epidemiology&rft.atitle=Prepregnancy+Body+Mass+Index+and+Gestational+Weight+Gain+in+Relation+to+Child+Body+Mass+Index+Among+Siblings&rft.au=Branum%2C+Amy+M%3BParker%2C+Jennifer+D%3BKeim%2C+Sarah+A%3BSchempf%2C+Ashley+H&rft.aulast=Branum&rft.aufirst=Amy&rft.date=2011-11-15&rft.volume=174&rft.issue=10&rft.spage=1159&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Epidemiology&rft.issn=00029262&rft_id=info:doi/10.1093%2Faje%2Fkwr250 LA - English DB - Physical Education Index; ProQuest Environmental Science Collection N1 - Date revised - 2012-01-01 N1 - Last updated - 2013-11-04 N1 - SubjectsTermNotLitGenreText - Obesity; Genetics; Programs; Age; Epidemiology; Weight; Body mass; Family; Children; environmental factors; body mass; obesity; siblings; body weight DO - http://dx.doi.org/10.1093/aje/kwr250 ER - TY - CPAPER T1 - Laboratory evaluation of methanol extracts from three plant species as repellents against a vector of scrub typhus, Leptotrombidium pallidum (Acari: Trombiculidae) T2 - 59th Annual Meeting of the Entomological Society of America AN - 1312944440; 6062886 JF - 59th Annual Meeting of the Entomological Society of America AU - Chang, Kyu AU - Shin, E AU - Park, Chan AU - Kim, Hyun Y1 - 2011/11/13/ PY - 2011 DA - 2011 Nov 13 KW - Scrub typhus KW - Plant extracts KW - Vectors KW - Repellents KW - Methanol KW - Globus pallidus KW - Pest control KW - Leptotrombidium pallidum KW - Acari KW - Trombiculidae UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312944440?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=59th+Annual+Meeting+of+the+Entomological+Society+of+America&rft.atitle=Laboratory+evaluation+of+methanol+extracts+from+three+plant+species+as+repellents+against+a+vector+of+scrub+typhus%2C+Leptotrombidium+pallidum+%28Acari%3A+Trombiculidae%29&rft.au=Chang%2C+Kyu%3BShin%2C+E%3BPark%2C+Chan%3BKim%2C+Hyun&rft.aulast=Chang&rft.aufirst=Kyu&rft.date=2011-11-13&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=59th+Annual+Meeting+of+the+Entomological+Society+of+America&rft.issn=&rft_id=info:doi/ L2 - http://esa.confex.com/esa/2011/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - JOUR T1 - Reduced Sexual Risk Behaviors Among People Living with HIV: Results from the Healthy Relationships Outcome Monitoring Project AN - 926890262; 16350724 AB - In 2006, the Centers for Disease Control and Prevention funded seven community-based organizations (CBOs) to conduct outcome monitoring of Healthy Relationships. Healthy Relationships is an evidence-based behavioral intervention for people living with HIV. Demographic and sexual risk behaviors recalled by participants with a time referent of the past 90 days were collected over a 17-month project period using a repeated measures design. Data were collected at baseline, and at 3 and 6 months after the intervention. Generalized estimating equations were used to assess the changes in sexual risk behaviors after participation in Healthy Relationships. Our findings show that participants (n = 474) in the outcome monitoring project reported decreased sexual risk behaviors over time, such as fewer number of partners (RR = 0.55; 95% CI 0.41-0.73, P < 0.001) and any unprotected sex events (OR = 0.44; 95% CI 0.36-0.54, P < 0.001) at 6 months after the intervention. Additionally, this project demonstrates that CBOs can successfully collect and report longitudinal outcome monitoring data. JF - AIDS and Behavior AU - Heitgerd, Janet L AU - Kalayil, Elizabeth J AU - Patel-Larson, Alpa AU - Uhl, Gary AU - Williams, Weston O AU - Griffin, Tanesha AU - Smith, Bryce D AD - Program Evaluation Branch, Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road, MS-E59, Atlanta, GA, 30333, USA, JHeitgerd@cdc.gov Y1 - 2011/11// PY - 2011 DA - Nov 2011 SP - 1677 EP - 1690 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 15 IS - 8 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - demography KW - sexual behavior KW - Acquired immune deficiency syndrome KW - Data processing KW - Mathematical models KW - Disease control KW - disease control KW - community involvement KW - Sexual behavior KW - Demography KW - Human immunodeficiency virus KW - intervention KW - prevention KW - Sex KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/926890262?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Reduced+Sexual+Risk+Behaviors+Among+People+Living+with+HIV%3A+Results+from+the+Healthy+Relationships+Outcome+Monitoring+Project&rft.au=Heitgerd%2C+Janet+L%3BKalayil%2C+Elizabeth+J%3BPatel-Larson%2C+Alpa%3BUhl%2C+Gary%3BWilliams%2C+Weston+O%3BGriffin%2C+Tanesha%3BSmith%2C+Bryce+D&rft.aulast=Heitgerd&rft.aufirst=Janet&rft.date=2011-11-01&rft.volume=15&rft.issue=8&rft.spage=1677&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-011-9913-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Demography; Mathematical models; Data processing; Disease control; Sexual behavior; Sex; demography; sexual behavior; Acquired immune deficiency syndrome; Human immunodeficiency virus; intervention; prevention; disease control; community involvement DO - http://dx.doi.org/10.1007/s10461-011-9913-2 ER - TY - JOUR T1 - Evaluation of an HIV Prevention Intervention for African Americans and Hispanics: Findings from the VOICES/VOCES Community-Based Organization Behavioral Outcomes Project AN - 926889863; 16350734 AB - There is limited knowledge about whether the delivery of evidence-based, HIV prevention interventions in 'real world' settings will produce outcomes similar to efficacy trial outcomes. In this study, we describe longitudinal changes in sexual risk outcomes among African American and Hispanic participants in the Video Opportunities for Innovative Condom Education and Safer Sex (VOICES/VOCES) program at four CDC-funded agencies. VOICES/VOCES was delivered to 922 high-risk individuals in a variety of community settings such as substance abuse treatment centers, housing complex centers, private residences, shelters, clinics, and colleges. Significant risk reductions were consistently observed at 30- and 120-days post-intervention for all outcome measures (e.g., unprotected sex, self-reported STD infection). Risk reductions were strongest for African American participants, although Hispanic participants also reported reducing their risky behaviors. These results suggest that, over a decade after the first diffusion of VOICES/VOCES across the U.S. by CDC, this intervention remains an effective tool for reducing HIV risk behaviors among high-risk African American and Hispanic individuals. JF - AIDS and Behavior AU - Fisher, Holly H AU - Patel-Larson, A AU - Green, K AU - Shapatava, E AU - Uhl, G AU - Kalayil, E J AU - Moore, A AU - Williams, W AU - Chen, B AD - Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road, MS-E59, Atlanta, GA, 30333, USA, hfisher@cdc.gov Y1 - 2011/11// PY - 2011 DA - Nov 2011 SP - 1691 EP - 1706 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 15 IS - 8 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - Acquired immune deficiency syndrome KW - Housing KW - Shelter KW - Infection KW - Drug abuse KW - community involvement KW - Condoms KW - risk reduction KW - USA KW - Human immunodeficiency virus KW - intervention KW - Risk factors KW - prevention KW - condoms KW - Risk groups KW - Diffusion KW - Ethnic groups KW - Sex KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/926889863?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Evaluation+of+an+HIV+Prevention+Intervention+for+African+Americans+and+Hispanics%3A+Findings+from+the+VOICES%2FVOCES+Community-Based+Organization+Behavioral+Outcomes+Project&rft.au=Fisher%2C+Holly+H%3BPatel-Larson%2C+A%3BGreen%2C+K%3BShapatava%2C+E%3BUhl%2C+G%3BKalayil%2C+E+J%3BMoore%2C+A%3BWilliams%2C+W%3BChen%2C+B&rft.aulast=Fisher&rft.aufirst=Holly&rft.date=2011-11-01&rft.volume=15&rft.issue=8&rft.spage=1691&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-011-9961-7 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Condoms; Housing; Risk factors; Risk groups; Diffusion; Shelter; Drug abuse; Infection; Sex; risk reduction; Acquired immune deficiency syndrome; Human immunodeficiency virus; intervention; condoms; prevention; community involvement; Ethnic groups; USA DO - http://dx.doi.org/10.1007/s10461-011-9961-7 ER - TY - JOUR T1 - Drinking behaviour among men and women in China: the 2007 China Chronic Disease and Risk Factor Surveillance AN - 920056742; 4266338 AB - Aim To obtain information on drinking behaviour and to examine the associations between frequency of drinking, usual daily drinking quantity and binge drinking behaviour among Chinese residents aged 15-69 years. Design: A multi-stage clustering sampling method was used to select a nationally representative sample and data were collected as part of the China Chronic Disease and Risk Factor Surveillance by face-to-face interview. Setting: Respondents were selected randomly from 160 counties/districts scattered over 31 provinces/autonomous regions/municipalities between August and October, 2007. Participants: Weighted analyses included 49 527 Chinese residents (aged 15-69 years). Measurements: Prevalence of current drinking and usual daily quantity, median number of annual binge drinking episodes, proportions of excessive drinking, frequent drinking and binge drinking among current drinkers were the main measurements. Results: The prevalence of male, female and total current drinking was 55.6%, 15.0% and 35.7%, respectively. On average, male drinkers consumed 47.8 g alcohol per drinking day, whereas females consumed 19.1 g. The median numbers of annual binge drinking episodes were 5.6 for male drinkers and 2.4 for females. Among the current drinkers, proportions of excessive drinking, frequent dinking and binge drinking were 62.7%, 26.3%, 57.3% for men and 51.0%, 7.8%, 26.6% for women, respectively. Logistic regressions showed that binge drinking was associated strongly with drinking frequency and drinking quantity increased with drinking frequency for both genders. Conclusions: Excessive drinking, frequent drinking and binge drinking behaviour have reached epidemic proportions among current drinkers in China, and culturally appropriate public health strategies to reduce hazardous drinking behaviour are needed. Reprinted by permission of Blackwell Publishing JF - Addiction AU - Zhang, Mei AU - Yin, Peng AU - Wu, Fan AU - Zhao, Wenhua AU - Li, Yichong AU - Jiang, Yong AD - Chinese Center for Disease Control and Prevention ; Shanghai Center for Disease Control and Prevention Y1 - 2011/11// PY - 2011 DA - Nov 2011 SP - 1946 EP - 1956 VL - 106 IS - 11 SN - 0965-2140, 0965-2140 KW - Sociology KW - Alcohol KW - Epidemics KW - Males KW - Gender KW - Alcoholism KW - Females KW - Diseases KW - China KW - Drinkers KW - Surveillance KW - Public health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/920056742?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Addiction&rft.atitle=Drinking+behaviour+among+men+and+women+in+China%3A+the+2007+China+Chronic+Disease+and+Risk+Factor+Surveillance&rft.au=Zhang%2C+Mei%3BYin%2C+Peng%3BWu%2C+Fan%3BZhao%2C+Wenhua%3BLi%2C+Yichong%3BJiang%2C+Yong&rft.aulast=Zhang&rft.aufirst=Mei&rft.date=2011-11-01&rft.volume=106&rft.issue=11&rft.spage=1946&rft.isbn=&rft.btitle=&rft.title=Addiction&rft.issn=09652140&rft_id=info:doi/10.1111%2Fj.1360-0443.2011.03514.x LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 3617 6220; 12424 6608 6085; 909; 913 561 6220; 3736; 4356 3617 6220; 5421 6091; 10449 5772; 7616 11538; 4865 11538; 93 116 30 DO - http://dx.doi.org/10.1111/j.1360-0443.2011.03514.x ER - TY - JOUR T1 - Impact of cigarette smoking on Volatile Organic Compound (VOC) blood levels in the U.S. Population: NHANES 2003-2004 AN - 918046383; 15552719 AB - The impact of cigarette smoking on volatile organic compound (VOC) blood levels is studied using 2003-2004 National Health and Nutrition Examination Survey (NHANES) data. Cigarette smoke exposure is shown to be a predominant source of benzene, toluene, ethylbenzene, xylenes and styrene (BTEXS) measured in blood as determined by (1) differences in central tendency and interquartile VOC blood levels between daily smokers [ greater than or equal to 1 cigarette per day (CPD)] and less-than-daily smokers, (2) correlation among BTEXS and the 2,5-dimethylfuran (2,5-DMF) smoking biomarker in the blood of daily smokers, and (3) regression modeling of BTEXS blood levels versus categorized CPD. Smoking status was determined by 2,5-DMF blood level using a cutpoint of 0.014ng/ml estimated by regression modeling of the weighted data and confirmed with receiver operator curve (ROC) analysis. The BTEXS blood levels among daily smokers were moderately-to-strongly correlated with 2,5-DMF blood levels (correlation coefficient, r, ranging from 0.46 to 0.92). Linear regression of the geometric mean BTEXS blood levels versus categorized CPD showed clear dose-response relationship (correlation of determination, R2, ranging from 0.81 to 0.98). Furthermore, the pattern of VOCs in blood of smokers is similar to that reported in mainstream cigarette smoke. These results show that cigarette smoking is a primary source of benzene, toluene and styrene and an important source of ethylbenzene and xylene exposure for the U.S. population, as well as the necessity of determining smoking status and factors affecting dose (e.g., CPD, time since last cigarette) in assessments involving BTEXS exposure. JF - Environment International AU - Chambers, David M AU - Ocariz, Jessica M AU - McGuirk, Maureen F AU - Blount, Benjamin C Y1 - 2011/11// PY - 2011 DA - Nov 2011 SP - 1321 EP - 1328 PB - Elsevier B.V., P.O. Box 800 Kidlington Oxford OX5 1DX United Kingdom VL - 37 IS - 8 SN - 0160-4120, 0160-4120 KW - Toxicology Abstracts; Environment Abstracts KW - Benzene, Toluene, Ethylbenzene, Xylene (BTEX) KW - Blood KW - Cigarette smoke KW - National Health and Nutrition Examination Survey (NHANES) KW - Volatile organic compound (VOC) KW - Bioindicators KW - Styrene KW - Data processing KW - Cigarettes KW - Toluene KW - Nutrition KW - biomarkers KW - Benzene KW - Blood levels KW - Smoke KW - USA KW - Xylene KW - Dose-response effects KW - Cigarette smoking KW - volatile organic compounds KW - Ethylbenzene KW - Volatile organic compounds KW - X 24380:Social Poisons & Drug Abuse KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/918046383?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environment+International&rft.atitle=Impact+of+cigarette+smoking+on+Volatile+Organic+Compound+%28VOC%29+blood+levels+in+the+U.S.+Population%3A+NHANES+2003-2004&rft.au=Chambers%2C+David+M%3BOcariz%2C+Jessica+M%3BMcGuirk%2C+Maureen+F%3BBlount%2C+Benjamin+C&rft.aulast=Chambers&rft.aufirst=David&rft.date=2011-11-01&rft.volume=37&rft.issue=8&rft.spage=1321&rft.isbn=&rft.btitle=&rft.title=Environment+International&rft.issn=01604120&rft_id=info:doi/10.1016%2Fj.envint.2011.05.016 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-01-01 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Styrene; Data processing; Toluene; Cigarette smoke; biomarkers; Nutrition; Benzene; Blood levels; Xylene; Dose-response effects; Cigarette smoking; volatile organic compounds; Ethylbenzene; Bioindicators; Smoke; Cigarettes; Volatile organic compounds; USA DO - http://dx.doi.org/10.1016/j.envint.2011.05.016 ER - TY - JOUR T1 - Multiple health behaviors and serum hepatic enzymes among US adults with obesity AN - 907190444; 16035622 AB - Introduction: This study was to examine the cumulative number and clustering patterns of low-risk health behaviors (i.e., not currently smoking, not excessive drinking, and physically active) associated with elevation of serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), and gamma-glutamyltransferase (GGT) among adults with obesity in the United States. Methods: We estimated the age-adjusted prevalence of elevated ALT, AST, and GGT from 4547 adults with obesity aged greater than or equal to 20 years who participated in the 2005-2008 National Health and Nutrition Examination Survey. The associations between the cumulative number or clustering patterns of low-risk health behaviors and measures of serum ALT, AST, and GGT were assessed using multivariate regression models. Results: Adult men who reported having three low-risk health behaviors were 62%, 39%, and 48% less likely to have elevated serum ALT, AST, and GGT, respectively; adult women were 56% and 73% less likely to have elevated serum AST and GGT, respectively, when compared to their respective counterparts who reported having none of the low-risk health behaviors. Conclusions: The findings of this study indicate that, among adults with obesity, having multiple low-risk health behaviors is associated with decreased likelihoods of elevated hepatic enzymes, including ALT in men, AST and GGT in both men and women. JF - Preventive Medicine AU - Tsai, James AU - Ford, Earl S AU - Zhao, Guixiang AU - Croft, Janet B AD - Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion Centers for Disease Control and Prevention, Atlanta, GA 30341, USA, jxt9@cdc.gov Y1 - 2011/11// PY - 2011 DA - Nov 2011 SP - 278 EP - 283 PB - Elsevier B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 53 IS - 4-5 SN - 0091-7435, 0091-7435 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Smoking KW - USA KW - Behavior KW - obesity KW - Enzymes KW - Nutrition KW - H 12000:Epidemiology and Public Health KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/907190444?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Preventive+Medicine&rft.atitle=Multiple+health+behaviors+and+serum+hepatic+enzymes+among+US+adults+with+obesity&rft.au=Tsai%2C+James%3BFord%2C+Earl+S%3BZhao%2C+Guixiang%3BCroft%2C+Janet+B&rft.aulast=Tsai&rft.aufirst=James&rft.date=2011-11-01&rft.volume=53&rft.issue=4-5&rft.spage=278&rft.isbn=&rft.btitle=&rft.title=Preventive+Medicine&rft.issn=00917435&rft_id=info:doi/10.1016%2Fj.ypmed.2011.08.028 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Smoking; Behavior; obesity; Enzymes; Nutrition; USA DO - http://dx.doi.org/10.1016/j.ypmed.2011.08.028 ER - TY - JOUR T1 - Relationships between hours of sleep and health-risk behaviors in US adolescent students AN - 907189349; 16035606 AB - Objective: To examine associations between insufficient sleep ( 1 time/day (AOR, 1.14; 95% CI, 1.03-1.28). Conclusion: Two-thirds of adolescent students reported insufficient sleep, which was associated with many health-risk behaviors. Greater awareness of the impact of sleep insufficiency is vital. JF - Preventive Medicine AU - McKnight-Eily, Lela R AU - Eaton, Danice K AU - Lowry, Richard AU - Croft, Janet B AU - Presley-Cantrell, Letitia AU - Perry, Geraldine S AD - Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Hwy, NE, MS K-67, Atlanta, GA 30341, USA, dvn1@cdc.gov Y1 - 2011/11// PY - 2011 DA - Nov 2011 SP - 271 EP - 273 PB - Elsevier B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 53 IS - 4-5 SN - 0091-7435, 0091-7435 KW - Health & Safety Science Abstracts; Risk Abstracts KW - Alcohol KW - Cigarettes KW - USA KW - schools KW - Behavior KW - Adolescents KW - suicide KW - H 0500:General KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/907189349?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Preventive+Medicine&rft.atitle=Relationships+between+hours+of+sleep+and+health-risk+behaviors+in+US+adolescent+students&rft.au=McKnight-Eily%2C+Lela+R%3BEaton%2C+Danice+K%3BLowry%2C+Richard%3BCroft%2C+Janet+B%3BPresley-Cantrell%2C+Letitia%3BPerry%2C+Geraldine+S&rft.aulast=McKnight-Eily&rft.aufirst=Lela&rft.date=2011-11-01&rft.volume=53&rft.issue=4-5&rft.spage=271&rft.isbn=&rft.btitle=&rft.title=Preventive+Medicine&rft.issn=00917435&rft_id=info:doi/10.1016%2Fj.ypmed.2011.06.020 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Alcohol; Cigarettes; Behavior; schools; suicide; Adolescents; USA DO - http://dx.doi.org/10.1016/j.ypmed.2011.06.020 ER - TY - JOUR T1 - Risk of Cardiovascular Mortality in Relation to Optimal Low-Density Lipoprotein Cholesterol Combined with Hypertriglyceridemia: Is There a Difference by Gender? AN - 904493564; 15913909 AB - Purpose: The objectives of the present study were to determine whether an optimal low-density lipoprotein cholesterol (LDL-C) combined with hypertriglyceridemia was associated with cardiovascular disease (CVD) mortality and whether these associations differ by gender. Methods: A cohort of 2903 U.S. adults aged =45 years (men) and =55 years (women) at baseline (1988-1994) was followed through December 2006 for CVD mortality. Baseline data were collected through the Third National Health and Nutrition Examination Survey (NHANES III). The definitions of high LDL-C and high triglycerides (TG) (hypertriglyceridemia) levels were based on the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) guidelines. Cox proportional hazard models were used to estimate the hazard ratio (HR) with 95% confidence interval (CI) of death. Results: After adjusting for age, race/ethnicity, and traditional CVD risk factors, the risk of CVD death was approximately two times as high among women with optimal LDL-C/hypertriglyceridemia (2.42, 95% CI = 1.35-4.33) compared to women with optimal LDL-C/normal TG. In contrast, no significant difference was found among men on this comparison. Conclusions: Judging from this study, hypertriglyceridemia is associated with an increased risk of CVD mortality in women but not in men. The association is independent of abnormal LDL-C effect. JF - Annals of Epidemiology AU - Kuklina, Elena V AU - Keenan, Nora L AU - Callaghan, William M AU - Hong, Yuling AD - Division for Heart Disease and Stroke Prevention, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, ekuklina@cdc.gov Y1 - 2011/11// PY - 2011 DA - Nov 2011 SP - 807 EP - 814 PB - Elsevier B.V., Box 882 New York NY 10159 United States VL - 21 IS - 11 SN - 1047-2797, 1047-2797 KW - Risk Abstracts KW - Mortality KW - cholesterol KW - Nutrition KW - USA KW - Education KW - guidelines KW - Risk factors KW - Gender KW - Cardiovascular diseases KW - Ethnic groups KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/904493564?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annals+of+Epidemiology&rft.atitle=Risk+of+Cardiovascular+Mortality+in+Relation+to+Optimal+Low-Density+Lipoprotein+Cholesterol+Combined+with+Hypertriglyceridemia%3A+Is+There+a+Difference+by+Gender%3F&rft.au=Kuklina%2C+Elena+V%3BKeenan%2C+Nora+L%3BCallaghan%2C+William+M%3BHong%2C+Yuling&rft.aulast=Kuklina&rft.aufirst=Elena&rft.date=2011-11-01&rft.volume=21&rft.issue=11&rft.spage=807&rft.isbn=&rft.btitle=&rft.title=Annals+of+Epidemiology&rft.issn=10472797&rft_id=info:doi/10.1016%2Fj.annepidem.2011.08.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Mortality; Education; guidelines; Risk factors; Gender; Cardiovascular diseases; Nutrition; cholesterol; Ethnic groups; USA DO - http://dx.doi.org/10.1016/j.annepidem.2011.08.004 ER - TY - JOUR T1 - Spatial analysis of scrub typhus infection and its association with environmental and socioeconomic factors in Taiwan AN - 902362377; 15699909 AB - We analyzed the spatial distribution of human cases of scrub typhus on the main island of Taiwan from 2003 to 2008 and implemented an island-wide survey of scrub typhus vectors (trombiculid chiggers) in 2007 and 2008. The standardized incidence rate 'SIR' incorporating inter-district variations in population, gender and age was correlated with environmental and socioeconomic variables. Higher incidence and SIR rates were clustered in the less developed, mountainous regions of central and eastern Taiwan. Higher SIRs were also associated with a higher proportion of dry-field farmers in the population, a higher normalized difference vegetation index (NDVI) and lower mean annual temperature, but was not associated with rainfall. Small mammal hosts in high-SIR districts harbored more chiggers and had higher rates of seropositivity against Orientia tsutsugamushi Hyashi, the etiologic agent of scrub typhus, compared to low-SIR districts. The concurrence of a higher proportion of dry-field farmers and higher NDVI has likely led to the clustering of scrub typhus in the mountainous regions of Taiwan. Further individual-level study of the risk factors associated with scrub typhus, and a better understanding of the effect of environmental factors on chigger abundance, should help to prevent scrub typhus in Taiwan. JF - Acta Tropica AU - Kuo, Chi-Chien AU - Huang, Jing-Lun AU - Ko, Chia-Ying AU - Lee, Pei-Fen AU - Wang, Hsi-Chieh Y1 - 2011/11// PY - 2011 DA - November 2011 SP - 52 EP - 58 PB - Elsevier B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 120 IS - 1-2 SN - 0001-706X, 0001-706X KW - Entomology Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 1: Biological Sciences & Living Resources KW - Environment KW - Orientia tsutsugamushi KW - Scrub typhus KW - Socioeconomic factors KW - Taiwan KW - Trombiculidae KW - Temperature effects KW - Age KW - Spatial distribution KW - Rainfall KW - Abundance KW - Vegetation KW - Vectors KW - Infection KW - Environmental factors KW - Socio-economic aspects KW - Islands KW - Risk factors KW - Sex KW - Z 05300:General KW - K 03450:Ecology KW - Q1 08604:Stock assessment and management KW - J 02450:Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/902362377?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Acta+Tropica&rft.atitle=Spatial+analysis+of+scrub+typhus+infection+and+its+association+with+environmental+and+socioeconomic+factors+in+Taiwan&rft.au=Kuo%2C+Chi-Chien%3BHuang%2C+Jing-Lun%3BKo%2C+Chia-Ying%3BLee%2C+Pei-Fen%3BWang%2C+Hsi-Chieh&rft.aulast=Kuo&rft.aufirst=Chi-Chien&rft.date=2011-11-01&rft.volume=120&rft.issue=1-2&rft.spage=52&rft.isbn=&rft.btitle=&rft.title=Acta+Tropica&rft.issn=0001706X&rft_id=info:doi/10.1016%2Fj.actatropica.2011.05.018 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2016-09-29 N1 - SubjectsTermNotLitGenreText - Environmental factors; Sex; Temperature effects; Age; Spatial distribution; Rainfall; Abundance; Vectors; Vegetation; Infection; Scrub typhus; Socio-economic aspects; Islands; Risk factors; Orientia tsutsugamushi DO - http://dx.doi.org/10.1016/j.actatropica.2011.05.018 ER - TY - JOUR T1 - Communities near toluene diisocyanate sources: an investigation of exposure and health. AN - 900627614; 21343954 AB - Toluene diisocyanate (TDI) is a well-known cause of occupational asthma, but we know little about the potential for exposure and health effects among residents who live near facilities that release TDI. In the mid-1990's, the North Carolina Department of Health and Human Services and the Agency for Toxic Substances and Disease Registry investigated exposures to TDI and health outcomes in one community, which left some unanswered questions. This cross-sectional study evaluated the potential associations between living near a TDI source and the prevalence of three variables: asthma or asthma-like respiratory symptoms, antibodies specific to TDI, and verifiable levels of TDI in residential air. Results among North Carolina residents living near such facilities (five target communities) were compared with the results from residents living further away (five comparison communities). Overall, the prevalence of reporting either asthma or asthma-like respiratory symptoms was higher (odds ratio = 1.60; 95% confidence interval = 0.97-2.54) among residents in target communities than those in comparison communities. However, this difference was not statistically significant. Symptom prevalence varied greatly among the community populations. The prevalence of respiratory symptoms was higher near facilities with historically higher TDI emissions. Among the 351 participants who provided blood samples, only one had immunoglobulin G specific antibodies to TDI. This participant lived in a target area and may have had non-occupational exposure. TDI was detected at an extremely low level (1 ppt) in one of the 45 air samples from target communities. One ppt is one-tenth the EPA reference concentration. Overall, air sample and antibody test results are not consistent with recent or ongoing exposure to TDI. JF - Journal of exposure science & environmental epidemiology AU - Wilder, Lynn C AU - Langley, Ricky L AU - Middleton, Dan C AU - Ernst, Kathleen AU - Lummus, Zana L AU - Streicher, Robert P AU - Campbell, Douglas S AU - Wattigney, Wendy A AU - Bernstein, Jonathan A AU - Bernstein, David I AU - Dearwent, Steve M AD - Agency for Toxic Substances and Disease Registry, Division of Health Studies, Atlanta, Georgia 30341, USA. lwilder@cdc.gov PY - 2011 SP - 587 EP - 594 VL - 21 IS - 6 KW - Immunoglobulin G KW - 0 KW - Toluene 2,4-Diisocyanate KW - 17X7AFZ1GH KW - Index Medicus KW - Immunoglobulin G -- blood KW - Cross-Sectional Studies KW - Humans KW - Surveys and Questionnaires KW - North Carolina -- epidemiology KW - Immunoglobulin G -- immunology KW - Time Factors KW - Male KW - Female KW - Toluene 2,4-Diisocyanate -- toxicity KW - Toluene 2,4-Diisocyanate -- immunology KW - Asthma, Occupational -- blood KW - Asthma, Occupational -- immunology KW - Asthma, Occupational -- chemically induced KW - Occupational Exposure -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/900627614?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+exposure+science+%26+environmental+epidemiology&rft.atitle=Communities+near+toluene+diisocyanate+sources%3A+an+investigation+of+exposure+and+health.&rft.au=Wilder%2C+Lynn+C%3BLangley%2C+Ricky+L%3BMiddleton%2C+Dan+C%3BErnst%2C+Kathleen%3BLummus%2C+Zana+L%3BStreicher%2C+Robert+P%3BCampbell%2C+Douglas+S%3BWattigney%2C+Wendy+A%3BBernstein%2C+Jonathan+A%3BBernstein%2C+David+I%3BDearwent%2C+Steve+M&rft.aulast=Wilder&rft.aufirst=Lynn&rft.date=2011-11-01&rft.volume=21&rft.issue=6&rft.spage=587&rft.isbn=&rft.btitle=&rft.title=Journal+of+exposure+science+%26+environmental+epidemiology&rft.issn=1559-064X&rft_id=info:doi/10.1038%2Fjes.2011.5 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-02-15 N1 - Date created - 2011-10-20 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1038/jes.2011.5 ER - TY - JOUR T1 - Frequency and type of microbiological monitoring of multidrug-resistant tuberculosis treatment. AN - 900625058; 22008772 AB - Monthly culture is usually recommended to monitor treatment of multidrug-resistant tuberculosis (MDR-TB). As mycobacterial laboratory capacity is limited in many settings, TB programs need evidence to decide whether monthly cultures are necessary compared to other approaches. We simulated three alternative monitoring strategies (culture every 2 or 3 months, and monthly smears alone) in a cohort of MDR-TB patients in Estonia, Latvia, Philippines, Russia and Peru from 2000 to 2004. This retrospective analysis illustrated that less frequent testing delays confirmation of bacteriological conversion. This would prolong intensive treatment, hospitalization and respiratory isolation, increasing cost and toxicity. After conversion, less frequent testing could delay diagnosis of possible treatment failure. JF - The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease AU - Kurbatova, E V AU - Gammino, V M AU - Bayona, J AU - Becerra, M AU - Danilovitz, M AU - Falzon, D AU - Gelmanova, I AU - Keshavjee, S AU - Leimane, V AU - Mitnick, C D AU - Quelapio, M I D AU - Riekstina, V AU - Taylor, A AU - Viiklepp, P AU - Zignol, M AU - Cegielski, J P AD - US Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. EKurbatova@cdc.gov Y1 - 2011/11// PY - 2011 DA - November 2011 SP - 1553 EP - 5, i VL - 15 IS - 11 KW - Antitubercular Agents KW - 0 KW - Index Medicus KW - Treatment Failure KW - Sputum -- microbiology KW - Computer Simulation KW - Humans KW - Adult KW - Retrospective Studies KW - Predictive Value of Tests KW - Europe -- epidemiology KW - Time Factors KW - Philippines -- epidemiology KW - Male KW - Female KW - Peru -- epidemiology KW - Mycobacterium tuberculosis -- growth & development KW - Drug Monitoring -- methods KW - Tuberculosis, Multidrug-Resistant -- microbiology KW - Mycobacterium tuberculosis -- drug effects KW - Drug Resistance, Multiple, Bacterial KW - Mycobacterium tuberculosis -- isolation & purification KW - Bacteriological Techniques KW - Tuberculosis, Multidrug-Resistant -- epidemiology KW - Tuberculosis, Multidrug-Resistant -- drug therapy KW - Antitubercular Agents -- therapeutic use KW - Tuberculosis, Multidrug-Resistant -- diagnosis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/900625058?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+international+journal+of+tuberculosis+and+lung+disease+%3A+the+official+journal+of+the+International+Union+against+Tuberculosis+and+Lung+Disease&rft.atitle=Frequency+and+type+of+microbiological+monitoring+of+multidrug-resistant+tuberculosis+treatment.&rft.au=Kurbatova%2C+E+V%3BGammino%2C+V+M%3BBayona%2C+J%3BBecerra%2C+M%3BDanilovitz%2C+M%3BFalzon%2C+D%3BGelmanova%2C+I%3BKeshavjee%2C+S%3BLeimane%2C+V%3BMitnick%2C+C+D%3BQuelapio%2C+M+I+D%3BRiekstina%2C+V%3BTaylor%2C+A%3BViiklepp%2C+P%3BZignol%2C+M%3BCegielski%2C+J+P&rft.aulast=Kurbatova&rft.aufirst=E&rft.date=2011-11-01&rft.volume=15&rft.issue=11&rft.spage=1553&rft.isbn=&rft.btitle=&rft.title=The+international+journal+of+tuberculosis+and+lung+disease+%3A+the+official+journal+of+the+International+Union+against+Tuberculosis+and+Lung+Disease&rft.issn=1815-7920&rft_id=info:doi/10.5588%2Fijtld.11.0101 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-02-10 N1 - Date created - 2011-10-19 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.5588/ijtld.11.0101 ER - TY - JOUR T1 - Potential Risk Estimation Drowning Index for Children (PREDIC): A pilot study from Matlab, Bangladesh AN - 899145151; 15553637 AB - Childhood drowning is a major public health problem that has been neglected in many low- and middle-income countries. In Matlab, rural Bangladesh, more than 40% of child deaths aged 1-4 years are due to drowning. The main objective of this paper was to develop and evaluate a childhood drowning risk prediction index. A literature review was carried out to document risk factors identified for childhood drowning in Bangladesh. The Newacheck model for special health care needs for children was adapted and applied to construct a childhood drowning risk index called "Potential Risk Estimation Drowning Index for Children" (PREDIC). Finally, the proposed PREDIC Index was applied to childhood drowning deaths and compared with the comparison group from children living in Matlab, Bangladesh. This pilot study used t-tests and Receiver Operating Characteristic (ROC) curve to analyze the results. The PREDIC index was applied to 302 drowning deaths and 624 children 0-4 years old living in Matlab. The results of t-test indicate that the drowned children had a statistically (t=-8.58, p=0.0001) significant higher mean PREDIC score (6.01) than those in comparison group (5.26). Drowning cases had a PREDIC score of 6 or more for 68% of the children however, the comparison group had 43% of the children with score of 6 or more which was statistically significant (t=-7.36, p<0.001). The area under the curve for the Receiver Operating Characteristic curve was 0.662. Index score construction was scientifically plausible; and the index is relatively complete, fairly accurate, and practical. The risk index can help identify and target high risk children with drowning prevention programs. PREDIC index needs to be further tested for its accuracy, feasibility and effectiveness in drowning risk reduction in Bangladesh and other countries. JF - Accident Analysis & Prevention AU - Borse, N N AU - Hyder, A A AU - Bishai, D AU - Baker, T AU - Arifeen, SE Y1 - 2011/11// PY - 2011 DA - Nov 2011 SP - 1901 EP - 1906 PB - Elsevier B.V., P.O. Box 800 Kidlington Oxford OX5 1DX United Kingdom VL - 43 IS - 6 SN - 0001-4575, 0001-4575 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Drowning KW - Childhood injury KW - Risk analysis KW - Risk index KW - Bangladesh Low- and middle-income countries KW - Mortality KW - risk reduction KW - Health care KW - Reviews KW - Risk factors KW - prevention KW - Children KW - Bangladesh KW - drowning KW - Public health KW - R2 23060:Medical and environmental health KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/899145151?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Accident+Analysis+%26+Prevention&rft.atitle=Potential+Risk+Estimation+Drowning+Index+for+Children+%28PREDIC%29%3A+A+pilot+study+from+Matlab%2C+Bangladesh&rft.au=Borse%2C+N+N%3BHyder%2C+A+A%3BBishai%2C+D%3BBaker%2C+T%3BArifeen%2C+SE&rft.aulast=Borse&rft.aufirst=N&rft.date=2011-11-01&rft.volume=43&rft.issue=6&rft.spage=1901&rft.isbn=&rft.btitle=&rft.title=Accident+Analysis+%26+Prevention&rft.issn=00014575&rft_id=info:doi/10.1016%2Fj.aap.2011.04.029 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - risk reduction; Mortality; Health care; Risk factors; Reviews; prevention; Children; drowning; Public health; Bangladesh DO - http://dx.doi.org/10.1016/j.aap.2011.04.029 ER - TY - JOUR T1 - Improving immunogenicity and effectiveness of influenza vaccine in older adults AN - 1020846521; 16580036 AB - Aging is associated with a decline in immune function (immunosenescence) that leads to progressive deterioration in both innate and adaptive immune functions. These changes contribute to the subsequent increased risk for infectious diseases and their sequelae. Vaccination is the most effective and inexpensive public health strategy for prevention of infection, despite the decreased efficacy of vaccines in older adults due to immunosenescence. The rapid rise in the older adult population globally represents a great challenge for vaccination programs. This article first addresses the status of innate and adaptive immune functions in aging and then focuses on influenza vaccine. The development history of influenza vaccines, current status, and potential strategies to improve the immunogenicity and vaccine effectiveness in older adults are discussed. JF - Expert Review of Vaccines AU - Cao, Weiping AU - Kim, Jin Hyang AU - Chirkova, Tatiana AU - Reber, Adrian J AU - Biber, Renata AU - Shay, David K AU - Sambhara, Suryaprakash AD - super(1)Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Bldg 15, SSB 611 B, 1600 Clifton Road, Atlanta, GA, USA, ssambhara@cdc.gov Y1 - 2011/11// PY - 2011 DA - Nov 2011 SP - 1529 EP - 1537 PB - Future Science Group (FSG), Unitec House, 2 Albert Place London N3 1QB United Kingdom VL - 10 IS - 11 SN - 1476-0584, 1476-0584 KW - Immunology Abstracts; Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - Aging KW - Complications KW - Immune response KW - Immunogenicity KW - Immunosenescence KW - Infection KW - Infectious diseases KW - Influenza KW - Prevention KW - Public health KW - Reviews KW - Vaccines KW - V 22350:Immunology KW - F 06910:Microorganisms & Parasites KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1020846521?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Expert+Review+of+Vaccines&rft.atitle=Improving+immunogenicity+and+effectiveness+of+influenza+vaccine+in+older+adults&rft.au=Cao%2C+Weiping%3BKim%2C+Jin+Hyang%3BChirkova%2C+Tatiana%3BReber%2C+Adrian+J%3BBiber%2C+Renata%3BShay%2C+David+K%3BSambhara%2C+Suryaprakash&rft.aulast=Cao&rft.aufirst=Weiping&rft.date=2011-11-01&rft.volume=10&rft.issue=11&rft.spage=1529&rft.isbn=&rft.btitle=&rft.title=Expert+Review+of+Vaccines&rft.issn=14760584&rft_id=info:doi/10.1586%2Ferv.11.137 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-06-01 N1 - Number of references - 88 N1 - Last updated - 2013-01-11 N1 - SubjectsTermNotLitGenreText - Influenza; Infectious diseases; Immunosenescence; Complications; Immunogenicity; Reviews; Aging; Immune response; Vaccines; Infection; Public health; Prevention DO - http://dx.doi.org/10.1586/erv.11.137 ER - TY - CPAPER T1 - Public Health in Partnership: Working Across Sectors for Sustainable and Healthy Communities T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1313020343; 6050023 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Bunnell, Rebecca Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Sustainable development KW - Public health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313020343?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Public+Health+in+Partnership%3A+Working+Across+Sectors+for+Sustainable+and+Healthy+Communities&rft.au=Bunnell%2C+Rebecca&rft.aulast=Bunnell&rft.aufirst=Rebecca&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Multi-Sector Collaboration in Communities Putting Prevention to Work: A Necessity in Building Healthy Communities T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1313020115; 6050019 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Bauer, Ursula Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - prevention UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313020115?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Multi-Sector+Collaboration+in+Communities+Putting+Prevention+to+Work%3A+A+Necessity+in+Building+Healthy+Communities&rft.au=Bauer%2C+Ursula&rft.aulast=Bauer&rft.aufirst=Ursula&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Association between Severity of Vision Impairment and Falls among People Aged 65 and Older Living in the Community: Findings from the BRFSS T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1313016721; 6050279 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Crews, John AU - Chou, Chiu-Fang AU - Stevens, Judy AU - Zhang, Xinzhi AU - Saaddine, Jinan Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Vision UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313016721?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Association+between+Severity+of+Vision+Impairment+and+Falls+among+People+Aged+65+and+Older+Living+in+the+Community%3A+Findings+from+the+BRFSS&rft.au=Crews%2C+John%3BChou%2C+Chiu-Fang%3BStevens%2C+Judy%3BZhang%2C+Xinzhi%3BSaaddine%2C+Jinan&rft.aulast=Crews&rft.aufirst=John&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Work-related asthma- Analysis of the Asthma Call-Back Survey T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1313015638; 6049199 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Knoeller, Gretchen Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Respiratory diseases KW - Asthma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313015638?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Work-related+asthma-+Analysis+of+the+Asthma+Call-Back+Survey&rft.au=Knoeller%2C+Gretchen&rft.aulast=Knoeller&rft.aufirst=Gretchen&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - National Prevention Strategy: America's Plan for Better Health and Wellness T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1313001521; 6048266 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Graffunder, Corinne Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - prevention UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313001521?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=National+Prevention+Strategy%3A+America%27s+Plan+for+Better+Health+and+Wellness&rft.au=Graffunder%2C+Corinne&rft.aulast=Graffunder&rft.aufirst=Corinne&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Does the mode of delivery affect breastfeeding? T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1313000535; 6051174 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Ahluwalia, Indu AU - Li, Ruowei AU - Morrow, Brian Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Breast feeding UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1313000535?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Does+the+mode+of+delivery+affect+breastfeeding%3F&rft.au=Ahluwalia%2C+Indu%3BLi%2C+Ruowei%3BMorrow%2C+Brian&rft.aulast=Ahluwalia&rft.aufirst=Indu&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Leveraging advances in Informatics to support data exchange between Public Health and Clinical Care T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312995189; 6051762 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Cahill, Eric AU - Gaffney, Marcus AU - Deng, Xidong Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Public health KW - informatics KW - Data processing KW - Informatics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312995189?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Leveraging+advances+in+Informatics+to+support+data+exchange+between+Public+Health+and+Clinical+Care&rft.au=Cahill%2C+Eric%3BGaffney%2C+Marcus%3BDeng%2C+Xidong&rft.aulast=Cahill&rft.aufirst=Eric&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Essentials for Childhood: Preventing Child Maltreatment by ensuring safe, stable, nurturing relationships (SSNRs) for children T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312992754; 6050951 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Alexander, Sandra Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Children KW - child abuse KW - Child abuse UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312992754?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Essentials+for+Childhood%3A+Preventing+Child+Maltreatment+by+ensuring+safe%2C+stable%2C+nurturing+relationships+%28SSNRs%29+for+children&rft.au=Alexander%2C+Sandra&rft.aulast=Alexander&rft.aufirst=Sandra&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Evidence Project: A Comprehensive Framework for Evidence-Based Decision-Making T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312992710; 6050950 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Wilkins, Natalie AU - Singer, Helen AU - Thigpen, Sally AU - Puddy, Richard Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Decision making UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312992710?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Evidence+Project%3A+A+Comprehensive+Framework+for+Evidence-Based+Decision-Making&rft.au=Wilkins%2C+Natalie%3BSinger%2C+Helen%3BThigpen%2C+Sally%3BPuddy%2C+Richard&rft.aulast=Wilkins&rft.aufirst=Natalie&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Disparities in Obesity among People With and Without Disabilities by Race/Ethnicity -- United States, 2005--2009 T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312983854; 6051359 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Ramon, Ismaila AU - Courtney-Long, Elizabeth AU - Cyrus, Alissa AU - Armour, Brian Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - USA KW - disabilities KW - obesity KW - Ethnic groups KW - Races KW - Obesity KW - Subpopulations UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312983854?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Disparities+in+Obesity+among+People+With+and+Without+Disabilities+by+Race%2FEthnicity+--+United+States%2C+2005--2009&rft.au=Ramon%2C+Ismaila%3BCourtney-Long%2C+Elizabeth%3BCyrus%2C+Alissa%3BArmour%2C+Brian&rft.aulast=Ramon&rft.aufirst=Ismaila&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Gender-Based Violence and Mental Health in Urban Refugees and Asylum Seekers in Kampala, Uganda T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312982367; 6049382 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Morof, Diane AU - Sami, Samira AU - Mangeni, Maria AU - Blanton, Curtis AU - Tomczyk, Basia Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Uganda KW - Uganda, Kampala KW - mental disorders KW - Violence KW - refugees KW - Mental disorders KW - Aggression UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312982367?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Gender-Based+Violence+and+Mental+Health+in+Urban+Refugees+and+Asylum+Seekers+in+Kampala%2C+Uganda&rft.au=Morof%2C+Diane%3BSami%2C+Samira%3BMangeni%2C+Maria%3BBlanton%2C+Curtis%3BTomczyk%2C+Basia&rft.aulast=Morof&rft.aufirst=Diane&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Why We Need Public Health and Health Policy T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312976005; 6048888 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Degutis, Linda Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - health policy KW - Public health KW - Policies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312976005?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Why+We+Need+Public+Health+and+Health+Policy&rft.au=Degutis%2C+Linda&rft.aulast=Degutis&rft.aufirst=Linda&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Using a Health Equity Lens for Policy and Environmental Change T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312971710; 6051155 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Brooks, Carolyn Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Environmental changes KW - Policies KW - Climatic changes UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312971710?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Using+a+Health+Equity+Lens+for+Policy+and+Environmental+Change&rft.au=Brooks%2C+Carolyn&rft.aulast=Brooks&rft.aufirst=Carolyn&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Integrating and evaluating social media as a part of your communications package: The honeymoon is over T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312964965; 6049065 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Burnett, Garrett Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Communication KW - Packaging UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312964965?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Integrating+and+evaluating+social+media+as+a+part+of+your+communications+package%3A+The+honeymoon+is+over&rft.au=Burnett%2C+Garrett&rft.aulast=Burnett&rft.aufirst=Garrett&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Lessons Learned at NIOSH: Using the Tools of Social Media to Build our Community of Practice T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312964926; 6049064 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Lum, Max Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Public health KW - Nutrition KW - Sports KW - Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312964926?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Lessons+Learned+at+NIOSH%3A+Using+the+Tools+of+Social+Media+to+Build+our+Community+of+Practice&rft.au=Lum%2C+Max&rft.aulast=Lum&rft.aufirst=Max&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - National Health Interview Survey T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312959953; 6048186 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Dahlhamer, James Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Public health KW - Nutrition KW - Sports KW - Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312959953?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=National+Health+Interview+Survey&rft.au=Dahlhamer%2C+James&rft.aulast=Dahlhamer&rft.aufirst=James&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - A look at deep vein thrombosis and pulmonary embolism: Building a better tomorrow T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312948966; 6050888 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Simmons, Gretchen AU - Critchley, Sara AU - Beckman, Michelle Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - thromboembolism KW - Lung KW - Thrombosis KW - Veins KW - Embolism KW - Circulatory system KW - Heart UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312948966?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=A+look+at+deep+vein+thrombosis+and+pulmonary+embolism%3A+Building+a+better+tomorrow&rft.au=Simmons%2C+Gretchen%3BCritchley%2C+Sara%3BBeckman%2C+Michelle&rft.aulast=Simmons&rft.aufirst=Gretchen&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - DBD: Building a better tomorrow T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312948913; 6050887 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Simmons, Gretchen Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Public health KW - Nutrition KW - Sports KW - Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312948913?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=DBD%3A+Building+a+better+tomorrow&rft.au=Simmons%2C+Gretchen&rft.aulast=Simmons&rft.aufirst=Gretchen&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Building community capacity to address violence and physical activity: An update from the Centers for Disease Control & Prevention T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312944008; 6050584 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Noonan, Rita Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - disease control KW - physical activity KW - Violence KW - prevention KW - Physical activity KW - Aggression KW - Disease control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312944008?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Building+community+capacity+to+address+violence+and+physical+activity%3A+An+update+from+the+Centers+for+Disease+Control+%26amp%3B+Prevention&rft.au=Noonan%2C+Rita&rft.aulast=Noonan&rft.aufirst=Rita&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - A public health framework for chronic obstructive pulmonary disease (COPD) T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312928972; 6051603 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Presley-Cantrell, Letitia AU - Sturgis, Stephanie AU - Perry, Geraldine AU - Croft, Janet Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Public health KW - chronic obstructive pulmonary disease KW - Chronic obstructive pulmonary disease UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312928972?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=A+public+health+framework+for+chronic+obstructive+pulmonary+disease+%28COPD%29&rft.au=Presley-Cantrell%2C+Letitia%3BSturgis%2C+Stephanie%3BPerry%2C+Geraldine%3BCroft%2C+Janet&rft.aulast=Presley-Cantrell&rft.aufirst=Letitia&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Gaps and improvements in the public health surveillance of chronic obstructive pulmonary disease (COPD) T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312928959; 6051602 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Croft, Janet AU - Presley-Cantrell, Letitia AU - Liu, Yong AU - Holt, James AU - Liao, Winston AU - Ford, Earl Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Public health KW - chronic obstructive pulmonary disease KW - Chronic obstructive pulmonary disease UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312928959?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Gaps+and+improvements+in+the+public+health+surveillance+of+chronic+obstructive+pulmonary+disease+%28COPD%29&rft.au=Croft%2C+Janet%3BPresley-Cantrell%2C+Letitia%3BLiu%2C+Yong%3BHolt%2C+James%3BLiao%2C+Winston%3BFord%2C+Earl&rft.aulast=Croft&rft.aufirst=Janet&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Act early initiative: A public health approach to early identification of young children with autism and other developmental disabilities T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312926746; 6050491 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Rhodes, Cheryl AU - Peacock, Georgina AU - Rotholz, David AU - Griffen, Adriane Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - disabilities KW - Public health KW - Children KW - Autism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312926746?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Act+early+initiative%3A+A+public+health+approach+to+early+identification+of+young+children+with+autism+and+other+developmental+disabilities&rft.au=Rhodes%2C+Cheryl%3BPeacock%2C+Georgina%3BRotholz%2C+David%3BGriffen%2C+Adriane&rft.aulast=Rhodes&rft.aufirst=Cheryl&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Wash your hands T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312925146; 6049519 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Rubin, Alan Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Hand UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312925146?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Wash+your+hands&rft.au=Rubin%2C+Alan&rft.aulast=Rubin&rft.aufirst=Alan&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - CDC Use of child functioning and disability measures in surveys and surveillance T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312922378; 6049277 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Krahn, Gloria Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - disabilities UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312922378?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=CDC+Use+of+child+functioning+and+disability+measures+in+surveys+and+surveillance&rft.au=Krahn%2C+Gloria&rft.aulast=Krahn&rft.aufirst=Gloria&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Does food insecurity affect food and drink intake among toddlers in Oregon? T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312918902; 6048357 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Cunningham, Timothy AU - Barradas, Danielle AU - Rosenberg, Kenneth AU - May, Ashleigh AU - Kroelinger, Charlan AU - Ahluwalia, Indu Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - food security KW - Food intake KW - Food KW - Beverages UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312918902?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Does+food+insecurity+affect+food+and+drink+intake+among+toddlers+in+Oregon%3F&rft.au=Cunningham%2C+Timothy%3BBarradas%2C+Danielle%3BRosenberg%2C+Kenneth%3BMay%2C+Ashleigh%3BKroelinger%2C+Charlan%3BAhluwalia%2C+Indu&rft.aulast=Cunningham&rft.aufirst=Timothy&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Enhancing Health Surveys through Linkage with Administrative and Geographic Data T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312916283; 6048193 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Parker, Jennifer Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Data processing UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312916283?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Enhancing+Health+Surveys+through+Linkage+with+Administrative+and+Geographic+Data&rft.au=Parker%2C+Jennifer&rft.aulast=Parker&rft.aufirst=Jennifer&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Acute Global Response and Re-building a System T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312907943; 6049837 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Tappero, Jordan Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Public health KW - Nutrition KW - Sports KW - Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312907943?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Acute+Global+Response+and+Re-building+a+System&rft.au=Tappero%2C+Jordan&rft.aulast=Tappero&rft.aufirst=Jordan&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Overview of Mental Health and Public Health Integration in addressing Community Health T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312906918; 6051430 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Giles, Wayne Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - mental disorders KW - Public health KW - Integration KW - Reviews KW - Mental disorders UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312906918?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Overview+of+Mental+Health+and+Public+Health+Integration+in+addressing+Community+Health&rft.au=Giles%2C+Wayne&rft.aulast=Giles&rft.aufirst=Wayne&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - CPAPER T1 - Rationale for standardizing the recommended fluoridation level T2 - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AN - 1312900577; 6049428 JF - 139th American Public Health Association Annual Meeting and Exposition (APHA 2011) AU - Beltran, Eugenio Y1 - 2011/10/29/ PY - 2011 DA - 2011 Oct 29 KW - Fluoridation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1312900577?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.atitle=Rationale+for+standardizing+the+recommended+fluoridation+level&rft.au=Beltran%2C+Eugenio&rft.aulast=Beltran&rft.aufirst=Eugenio&rft.date=2011-10-29&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=139th+American+Public+Health+Association+Annual+Meeting+and+Exposition+%28APHA+2011%29&rft.issn=&rft_id=info:doi/ L2 - http://apha.confex.com/apha/139am/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-02-26 N1 - Last updated - 2013-02-28 ER - TY - JOUR T1 - A history of MMWR. AN - 896826229; 21976161 JF - MMWR supplements AU - Shaw, Frederic E AU - Goodman, Richard A AU - Lindegren, Mary Lou AU - Ward, John W AU - Centers for Disease Control and Prevention (CDC) AD - Public Health Surveillance Program Office, Office of Surveillance, Epidemiology and Laboratory Services, CDC, Atlanta, Georgia 30333, USA. fxs6@cdc.gov ; Centers for Disease Control and Prevention (CDC) Y1 - 2011/10/07/ PY - 2011 DA - 2011 Oct 07 SP - 7 EP - 14 VL - 60 IS - 4 KW - Index Medicus KW - United States KW - Publishing -- trends KW - Wounds and Injuries -- epidemiology KW - History, 21st Century KW - History, 20th Century KW - Disease Notification -- history KW - Environmental Health KW - Centers for Disease Control and Prevention (U.S.) KW - Humans KW - History, 19th Century KW - Chronic Disease -- epidemiology KW - Periodicals as Topic -- history KW - Public Health -- history KW - Population Surveillance UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/896826229?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=MMWR+supplements&rft.atitle=A+history+of+MMWR.&rft.au=Shaw%2C+Frederic+E%3BGoodman%2C+Richard+A%3BLindegren%2C+Mary+Lou%3BWard%2C+John+W%3BCenters+for+Disease+Control+and+Prevention+%28CDC%29&rft.aulast=Shaw&rft.aufirst=Frederic&rft.date=2011-10-07&rft.volume=60&rft.issue=4&rft.spage=7&rft.isbn=&rft.btitle=&rft.title=MMWR+supplements&rft.issn=2380-8942&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-11-14 N1 - Date created - 2011-10-06 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Disparities in the prevalence of smoke alarms in U.S. households: Conclusions drawn from published case studies AN - 912921983; 16128555 AB - Introduction: Deaths from fires and burns are a leading cause of fatal home injury in the United States. Smoke alarms are one of the most effective interventions to prevent residential fire deaths. Nationwide, more than 95% of homes are estimated to have at least one smoke alarm. There is evidence that homes at highest risk of fire deaths lag behind national averages in smoke alarm use and maintenance. Method: We compiled a comprehensive list of published studies that focus on smoke alarm prevalence in high-risk homes. Our findings show that there are substantial gaps in both smoke alarm presence and functional status between high-risk homes and national average estimates. Conclusions: To save more lives, improved efforts are needed to reduce the disparity in smoke alarm prevalence and functional use in the United States. JF - Journal of Safety Research AU - Liu, Ying AU - Holland, Amy E AU - Mack, Karin AU - Diekman, Shane AD - Centers for Disease Control and Prevention, National Center for Injury Prevention and Control, USA, aholland@cdc.gov Y1 - 2011/10// PY - 2011 DA - Oct 2011 SP - 409 EP - 413 PB - Elsevier B.V., P.O. Box 800 Kidlington Oxford OX5 1DX United Kingdom VL - 42 IS - 5 SN - 0022-4375, 0022-4375 KW - Health & Safety Science Abstracts KW - Burns KW - case studies KW - Fires KW - Mortality KW - USA KW - households KW - Injuries KW - Alarm systems KW - intervention KW - Maintenance KW - H 7000:Fire Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/912921983?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Safety+Research&rft.atitle=Disparities+in+the+prevalence+of+smoke+alarms+in+U.S.+households%3A+Conclusions+drawn+from+published+case+studies&rft.au=Liu%2C+Ying%3BHolland%2C+Amy+E%3BMack%2C+Karin%3BDiekman%2C+Shane&rft.aulast=Liu&rft.aufirst=Ying&rft.date=2011-10-01&rft.volume=42&rft.issue=5&rft.spage=409&rft.isbn=&rft.btitle=&rft.title=Journal+of+Safety+Research&rft.issn=00224375&rft_id=info:doi/10.1016%2Fj.jsr.2011.10.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-12-01 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - case studies; Burns; Mortality; Fires; households; Injuries; intervention; Alarm systems; Maintenance; USA DO - http://dx.doi.org/10.1016/j.jsr.2011.10.001 ER - TY - JOUR T1 - A Review of Physical and Mental Health Consequences of Child Abuse and Neglect and Implications for Practice AN - 899154290; 15620381 AB - This article provides an overview of mental and physical health outcomes of child maltreatment to help health care providers identify the consequences of maltreatment and consider treatment options. Child maltreatment is associated with a variety of negative physical and mental health outcomes that affect the individual throughout the lifespan and place a substantial burden on both victims and the population as a whole. The review begins with an overview of the role of physicians in identifying abuse and neglect in the clinic setting. Next, current research findings on physical and mental health outcomes in children, adolescents, and adults are reviewed. Finally, opportunities for primary prevention of abuse and neglect are discussed. Primary prevention strategies can avoid risk for maltreatment, and subsequent interventions for victims have the potential to greatly improve their health. JF - American Journal of Lifestyle Medicine AU - Leeb, Rebecca T AU - Lewis, Terri AU - Zolotor, Adam J AD -  , RLeeb@CDC.gov Y1 - 2011/10// PY - 2011 DA - Oct 2011 SP - 454 EP - 468 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU United Kingdom VL - 5 IS - 5 SN - 1559-8276, 1559-8276 KW - Risk Abstracts KW - Children KW - Health care KW - Reviews KW - intervention KW - prevention KW - mental disorders KW - Adolescents KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/899154290?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Lifestyle+Medicine&rft.atitle=A+Review+of+Physical+and+Mental+Health+Consequences+of+Child+Abuse+and+Neglect+and+Implications+for+Practice&rft.au=Leeb%2C+Rebecca+T%3BLewis%2C+Terri%3BZolotor%2C+Adam+J&rft.aulast=Leeb&rft.aufirst=Rebecca&rft.date=2011-10-01&rft.volume=5&rft.issue=5&rft.spage=454&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Lifestyle+Medicine&rft.issn=15598276&rft_id=info:doi/10.1177%2F1559827611410266 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Health care; intervention; Reviews; prevention; Children; mental disorders; Adolescents DO - http://dx.doi.org/10.1177/1559827611410266 ER - TY - JOUR T1 - Intimate Partner Violence and Adverse Health Consequences: Implications for Clinicians AN - 899154273; 15620380 AB - Nearly 1 in 4 women and 1 in 13 men experience intimate partner violence (IPV) at some time in their life. Victims of IPV suffer significant negative health consequences because of the physical, sexual, and emotional abuse they have experienced. Elevated risks have been observed for a wide range of adverse health outcomes. Research has substantially improved our understanding of the physiology that underlies the association between violence victimization and an array of adverse health outcomes. Given the high prevalence of IPV and the associated medical consequences and costs of IPV, it is critical to address this public health problem. IPV prevention and intervention can substantially decrease the public health burden of IPV and greatly improve the health of patients being seen in the medical system. Primary care and family physicians are in an ideal position to diagnose victims of IPV and provide the victims and their families the appropriate care that is needed. However, to accomplish this goal, there remains an urgent need to integrate information on IPV into medical and health care curricula, and to train future physicians and other health care providers about the pervasiveness of IPV and the far-reaching implications for patient health. JF - American Journal of Lifestyle Medicine AU - Black, Michele C AD - Centers for Disease Control and Prevention, Atlanta, Georgia  , mcl2@cdc.gov Y1 - 2011/10// PY - 2011 DA - Oct 2011 SP - 428 EP - 439 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU United Kingdom VL - 5 IS - 5 SN - 1559-8276, 1559-8276 KW - Risk Abstracts KW - Physiology KW - domestic violence KW - victimization KW - Violence KW - Public health KW - Health care KW - intervention KW - prevention KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/899154273?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Lifestyle+Medicine&rft.atitle=Intimate+Partner+Violence+and+Adverse+Health+Consequences%3A+Implications+for+Clinicians&rft.au=Black%2C+Michele+C&rft.aulast=Black&rft.aufirst=Michele&rft.date=2011-10-01&rft.volume=5&rft.issue=5&rft.spage=428&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Lifestyle+Medicine&rft.issn=15598276&rft_id=info:doi/10.1177%2F1559827611410265 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Health care; intervention; Physiology; prevention; domestic violence; victimization; Violence; Public health DO - http://dx.doi.org/10.1177/1559827611410265 ER - TY - JOUR T1 - Violence and Men's Health: Understanding the Etiological Underpinnings of Men's Experiences With Interpersonal Violence AN - 899154260; 15620379 AB - Although violence affects everyone, men's health is disproportionately affected. To better understand the etiology of men's violence, it is essential to comprehensively examine the factors influencing the development and trajectories of violence perpetration and victimization. This review offers a broad perspective on the burden of violence for men and the characteristics of individuals, relationships, communities, and society that combine to influence men's experience with interpersonal violence, including child maltreatment, youth violence, intimate partner violence, and sexual violence. Men's experience with violence is influenced by physiological, emotional, and behavioral factors; relationships with family and peers; and social norms. In collaboration with professionals from other sectors, health professionals can help prevent or intervene in male's perpetration of violence across the lifespan through identification of factors that place men at risk and referral of male patients to evidence-based prevention and intervention resources. JF - American Journal of Lifestyle Medicine AU - Haegerich, Tamara M AU - Hall, Jeffrey E Y1 - 2011/10// PY - 2011 DA - Oct 2011 SP - 440 EP - 453 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU United Kingdom VL - 5 IS - 5 SN - 1559-8276, 1559-8276 KW - Risk Abstracts KW - Reviews KW - intervention KW - child abuse KW - prevention KW - males KW - domestic violence KW - victimization KW - Violence KW - sexual assault KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/899154260?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Lifestyle+Medicine&rft.atitle=Violence+and+Men%27s+Health%3A+Understanding+the+Etiological+Underpinnings+of+Men%27s+Experiences+With+Interpersonal+Violence&rft.au=Haegerich%2C+Tamara+M%3BHall%2C+Jeffrey+E&rft.aulast=Haegerich&rft.aufirst=Tamara&rft.date=2011-10-01&rft.volume=5&rft.issue=5&rft.spage=440&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Lifestyle+Medicine&rft.issn=15598276&rft_id=info:doi/10.1177%2F1559827611410263 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Number of references - 170 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - child abuse; intervention; Reviews; prevention; domestic violence; males; victimization; sexual assault; Violence DO - http://dx.doi.org/10.1177/1559827611410263 ER - TY - JOUR T1 - Addressing Self-Directed Violence Prevention for Preventive Medicine Practitioners AN - 899154248; 15620378 AB - This article summarizes the field of self-directed violence and its prevention focusing on suicidal behavior. Then it describes ways in which health care practitioners, especially preventive medicine specialists, can play a role in preventing these injuries whether they practice in clinical or community based settings. A review of the importance of suicidal behavior as a public health problem, its epidemiology, and prevention approaches are discussed. Suicidal behavior results from an interaction of risk factors but much is known about these factors and many of the injuries due to this phenomenon are preventable. Prevention of suicidal behavior requires collaboration from many sectors, including health care practitioners. Preventive medicine specialists can address this problem that affects individuals, families, and communities by taking an active part as practitioners, researchers, advocates, and through education. JF - American Journal of Lifestyle Medicine AU - Crosby, Alex E AU - Buckner, Ayanna V AU - Taylor, Beverly D AD -  , aec1@cdc.gov Y1 - 2011/10// PY - 2011 DA - Oct 2011 SP - 418 EP - 427 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU United Kingdom VL - 5 IS - 5 SN - 1559-8276, 1559-8276 KW - Risk Abstracts KW - Injuries KW - Violence KW - community involvement KW - Public health KW - Education KW - Health care KW - Reviews KW - prevention KW - suicide KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/899154248?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Lifestyle+Medicine&rft.atitle=Addressing+Self-Directed+Violence+Prevention+for+Preventive+Medicine+Practitioners&rft.au=Crosby%2C+Alex+E%3BBuckner%2C+Ayanna+V%3BTaylor%2C+Beverly+D&rft.aulast=Crosby&rft.aufirst=Alex&rft.date=2011-10-01&rft.volume=5&rft.issue=5&rft.spage=418&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Lifestyle+Medicine&rft.issn=15598276&rft_id=info:doi/10.1177%2F1559827611410020 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Education; Injuries; Health care; Reviews; prevention; community involvement; Violence; suicide; Public health DO - http://dx.doi.org/10.1177/1559827611410020 ER - TY - JOUR T1 - Violence as a Public Health Risk AN - 899154230; 15620376 AB - Violence is a public health problem that affects people of all ages. In 2007, violence was one of the top 10 leading causes of death in the United States for people from birth to age 64 years. Violence takes many forms, such as child maltreatment, intimate partner violence, sexual violence, self-directed violence, and youth violence. Violence may be best understood and prevented through a public health approach. A focus is placed on preventing violence before it occurs (primary prevention), employing a scientific approach to understand the problem and what action can be taken to prevent it, taking a population perspective that places an emphasis on broad-based changes in communities and society that benefit the largest number of people, and working across sectors (eg, health, justice, education) and integrating knowledge from multiple disciplines (eg, epidemiology, psychology, sociology, medicine). In this article, the authors review the incidence and burden of different forms of violence and the factors that place people at risk for, or protect people from, experiencing violence either as a victim or as a perpetrator. The authors also review strategies based on the best available evidence that may be implemented to prevent violence from occurring, highlighting violence prevention tools for health practitioners. By understanding the burden of violence, the factors that place people at risk for and protect people from experiencing violence, and strategies that can prevent and interrupt violence, health practitioners can play a more active role in enhancing the health and safety of their patients. JF - American Journal of Lifestyle Medicine AU - Haegerich, Tamara M AU - Dahlberg, Linda L AD - Centers for Disease Control and Prevention, Atlanta, Georgia  , eqd4@cdc.gov Y1 - 2011/10// PY - 2011 DA - Oct 2011 SP - 392 EP - 406 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU United Kingdom VL - 5 IS - 5 SN - 1559-8276, 1559-8276 KW - Health & Safety Science Abstracts; Risk Abstracts KW - Mortality KW - Age KW - Sociology KW - domestic violence KW - Violence KW - Public health KW - USA KW - Education KW - Reviews KW - prevention KW - H 11000:Diseases/Injuries/Trauma KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/899154230?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Lifestyle+Medicine&rft.atitle=Violence+as+a+Public+Health+Risk&rft.au=Haegerich%2C+Tamara+M%3BDahlberg%2C+Linda+L&rft.aulast=Haegerich&rft.aufirst=Tamara&rft.date=2011-10-01&rft.volume=5&rft.issue=5&rft.spage=392&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Lifestyle+Medicine&rft.issn=15598276&rft_id=info:doi/10.1177%2F1559827611409127 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Mortality; Education; Sociology; Age; Reviews; prevention; domestic violence; Violence; Public health; USA DO - http://dx.doi.org/10.1177/1559827611409127 ER - TY - JOUR T1 - Poisoning hospitalisations among reproductive-aged women in the USA, 1998-2006. AN - 894040928; 21296799 AB - To describe poisoning hospitalisations among reproductive-aged women from 1998 to 2006. 1998-2006 data from the Nationwide Inpatient Sample of the Healthcare Cost and Utilisation Project were used to identify hospitalisations for poisonings among US women aged 15-44 years. Differences in hospitalisation characteristics were compared by intent using χ(2) statistics. Trends in poisoning hospitalisation rates were calculated overall and by subgroup. There were approximately 636,000 poisoning hospitalisations in women aged 15-44 years during 1998-2006. Hospitalisations for intentionally self-inflicted poisonings had a higher proportion of women aged 15-24 years and privately insured women than did unintentional poisonings (p<0.001). Poisoning hospitalisations in rural areas and those that resulted in death were more likely to be of undetermined intent than those for which intent was specified (p<0.001). Co-diagnoses of substance abuse (34.5%) or mental disorders (66.5%) were high. The rate of poisoning hospitalisations overall and unintentional poisoning hospitalisations increased 6% and 22%, respectively, during this period (p<0.001). The most frequently diagnosed poisoning agent was acetaminophen. Poisonings attributable to acetaminophen, opioids, central nervous system stimulants and benzodiazepines increased, while poisonings attributable to antidepressants decreased (p<0.05). The increase in unintentional poisoning hospitalisations among women aged 15-44 years and the changing profile of poisoning agents should inform the healthcare community's poisoning prevention strategies. Poisoning prevention strategies should include a component to address substance abuse and mental health disorders among reproductive-age women. JF - Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention AU - Cox, Shanna AU - Kuo, Cassie AU - Jamieson, Denise J AU - Kourtis, Athena P AU - McPheeters, Melissa L AU - Meikle, Susan F AU - Posner, Samuel F AD - Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway, Atlanta, GA 30341, USA. shanna.cox@cdc.hhs.gov Y1 - 2011/10// PY - 2011 DA - October 2011 SP - 332 EP - 337 VL - 17 IS - 5 KW - Index Medicus KW - Young Adult KW - Risk Factors KW - Mental Disorders -- epidemiology KW - Humans KW - Adult KW - Self-Injurious Behavior -- epidemiology KW - Adolescent KW - United States -- epidemiology KW - Female KW - Substance-Related Disorders -- epidemiology KW - Poisoning -- epidemiology KW - Hospitalization -- statistics & numerical data KW - Hospitalization -- trends UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/894040928?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Injury+prevention+%3A+journal+of+the+International+Society+for+Child+and+Adolescent+Injury+Prevention&rft.atitle=Poisoning+hospitalisations+among+reproductive-aged+women+in+the+USA%2C+1998-2006.&rft.au=Cox%2C+Shanna%3BKuo%2C+Cassie%3BJamieson%2C+Denise+J%3BKourtis%2C+Athena+P%3BMcPheeters%2C+Melissa+L%3BMeikle%2C+Susan+F%3BPosner%2C+Samuel+F&rft.aulast=Cox&rft.aufirst=Shanna&rft.date=2011-10-01&rft.volume=17&rft.issue=5&rft.spage=332&rft.isbn=&rft.btitle=&rft.title=Injury+prevention+%3A+journal+of+the+International+Society+for+Child+and+Adolescent+Injury+Prevention&rft.issn=1475-5785&rft_id=info:doi/10.1136%2Fip.2010.029793 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-12-12 N1 - Date created - 2011-09-23 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1136/ip.2010.029793 ER - TY - JOUR T1 - Accuracy and precision of Legionella isolation by US laboratories in the ELITE program pilot study AN - 883040203; 15381162 AB - A pilot study for the Environmental Legionella Isolation Techniques Evaluation (ELITE) Program, a proficiency testing scheme for US laboratories that culture Legionella from environmental samples, was conducted September 1, 2008 through March 31, 2009. Participants (n=20) processed panels consisting of six sample types: pure and mixed positive, pure and mixed negative, pure and mixed variable. The majority (93%) of all samples (n=286) were correctly characterized, with 88.5% of samples positive for Legionella and 100% of negative samples identified correctly. Variable samples were incorrectly identified as negative in 36.9% of reports. For all samples reported positive (n=128), participants underestimated the cfu/ml by a mean of 1.25 logs with standard deviation of 0.78 logs, standard error of 0.07 logs, and a range of 3.57 logs compared to the CDC re-test value. Centering results around the interlaboratory mean yielded a standard deviation of 0.65 logs, standard error of 0.06 logs, and a range of 3.22 logs. Sampling protocol, treatment regimen, culture procedure, and laboratory experience did not significantly affect the accuracy or precision of reported concentrations. Qualitative and quantitative results from the ELITE pilot study were similar to reports from a corresponding proficiency testing scheme available in the European Union, indicating these results are probably valid for most environmental laboratories worldwide. The large enumeration error observed suggests that the need for remediation of a water system should not be determined solely by the concentration of Legionella observed in a sample since that value is likely to underestimate the true level of contamination. JF - Water Research AU - Lucas, Claressa E AU - Taylor, Thomas H AU - Fields, Barry S Y1 - 2011/10/01/ PY - 2011 DA - 2011 Oct 01 SP - 4428 EP - 4436 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 45 IS - 15 SN - 0043-1354, 0043-1354 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Aqualine Abstracts; Water Resources Abstracts; Microbiology Abstracts B: Bacteriology; Environment Abstracts KW - Bioremediation KW - Contamination KW - Isolation KW - Standard Deviation KW - Sampling KW - Legionella KW - Testing Procedures KW - Environmental monitoring KW - Laboratories KW - Errors KW - USA KW - Bacteria (Legionellaceae) KW - European Union KW - Standard deviation KW - Colony-forming cells KW - Precision KW - Remediation KW - Cultures KW - Standards KW - AQ 00001:Water Resources and Supplies KW - Q5 08502:Methods and instruments KW - ENA 08:International KW - SW 7060:Research facilities KW - J 02300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/883040203?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Water+Research&rft.atitle=Accuracy+and+precision+of+Legionella+isolation+by+US+laboratories+in+the+ELITE+program+pilot+study&rft.au=Lucas%2C+Claressa+E%3BTaylor%2C+Thomas+H%3BFields%2C+Barry+S&rft.aulast=Lucas&rft.aufirst=Claressa&rft.date=2011-10-01&rft.volume=45&rft.issue=15&rft.spage=4428&rft.isbn=&rft.btitle=&rft.title=Water+Research&rft.issn=00431354&rft_id=info:doi/10.1016%2Fj.watres.2011.05.030 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-08-01 N1 - Number of references - 6 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Contamination; Remediation; Standard deviation; Colony-forming cells; Sampling; Environmental monitoring; Bioremediation; Testing Procedures; Bacteria (Legionellaceae); Standard Deviation; Laboratories; Precision; Cultures; Standards; Isolation; Errors; Legionella; USA; European Union DO - http://dx.doi.org/10.1016/j.watres.2011.05.030 ER - TY - JOUR T1 - Is geology risky to human health? How do we know? AN - 1473587783; 2013-005509 AB - For infectious disease, Koch's postulates showed that the tubercule bacillus caused tuberculosis. For environmental hazards and chronic disease, it is more complex: multiple risk factors, and weaker relationships require testing associations, not cause. Bradford-Hill's nine criteria were used to show the association between cigarette smoking and lung cancer. Such research requires large nationally representative datasets with both the risk factors and the outcomes. Statistical techniques include multivariate or multilevel models rather than direct experiments. Tests reveal associations, not cause. A natural experiment revealed an environmental effect on health when federal researchers used the National Health and Examination Survey to show that eliminating lead in gasoline resulted in a significant reduction in blood lead levels in the US population. The National Center for Health Statistics hosts many such health datasets, and can link in external datasets with environmental or geologic risk factors, such as air and water pollution data from the Environmental Protection Agency. Such hazards can be linked through geocoded variables of state, county, census tract, and latitude and longitude. Any kind of environmental hazard data can be linked, if coded by one or more such variables. If you have a hypothesis on a relationship between geology and human health, we have some data! JF - Abstracts with Programs - Geological Society of America AU - Rose, Deborah AU - Anonymous Y1 - 2011/10// PY - 2011 DA - October 2011 SP - 241 PB - Geological Society of America (GSA), Boulder, CO VL - 43 IS - 5 SN - 0016-7592, 0016-7592 KW - toxicity KW - geologic hazards KW - natural hazards KW - risk assessment KW - public health KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1473587783?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Abstracts+with+Programs+-+Geological+Society+of+America&rft.atitle=Is+geology+risky+to+human+health%3F+How+do+we+know%3F&rft.au=Rose%2C+Deborah%3BAnonymous&rft.aulast=Rose&rft.aufirst=Deborah&rft.date=2011-10-01&rft.volume=43&rft.issue=5&rft.spage=241&rft.isbn=&rft.btitle=&rft.title=Abstracts+with+Programs+-+Geological+Society+of+America&rft.issn=00167592&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Geological Society of America, 2011 annual meeting N1 - Copyright - GeoRef, Copyright 2013, American Geosciences Institute. Reference includes data supplied by the Geological Society of America, Boulder, CO, United States N1 - Date revised - 2013-01-01 N1 - PubXState - CO N1 - Last updated - 2014-01-02 N1 - CODEN - GAAPBC N1 - SubjectsTermNotLitGenreText - geologic hazards; natural hazards; public health; risk assessment; toxicity ER - TY - JOUR T1 - Primary Antibiotic Resistance of Helicobacter pylori Isolated from Beijing Children AN - 1328507438; 15929940 AB - Background: The antimicrobials resistance of Helicobacter pylori (H. pylori) was able to sharply decline the eradication rate of H. pylori both in adults and children, but there are limited studies about the primary antibiotic resistance and the related gene mutations, specifically in China. Materials and Methods: The primary resistance to 9 antibiotics of 73 H. pylori strains isolated from gastric biopsies of children recruited at Beijing Children's Hospital was assessed, and the mutations in 23S rRNA gene of 65 macrolide-resistant strains and in gyrA and gyrB of 12 quinolone-resistant strains were investigated. Results: The resistance rate to clarithromycin, azithromycin, metronidazole, levofloxacin, moxifloxacin, and rifampicin was 84.9%, 87.7%, 61.6%, 13.7%, 15.1%, and 6.8%, respectively. No resistance to amoxicillin, gentamicin, and tetracycline was observed. Dual, triple, and quadruple antibacterial resistant percentage was 46.6% (34/73), 15.1% (11/73), and 2.7% (2/73), respectively. The gene mutation rate of A2142C, A2142G, and A2143G in 23S rRNA gene was 1.5% (1/65), 6.2% (4/65), and 84.6% (55/65), respectively. The detection rate of mutations of Asn87, Asp91, and Met191 in GyrA was 41.7% (5/12), 25% (3/12), and 25% (3/12), respectively. Conclusion: The high prevalence of primary antibiotic resistance was out of expectation in H. pylori strains isolated from the children in Beijing. Antibiotic susceptibility should be made clear before the antibiotic was used in the anti-H. pylori therapy in this population. The A2143G was the most populated mutation in macrolide-resistant strains, and Asn87 and Asp91 of GyrA were the most common mutation points in quinolone resistance strains. JF - Helicobacter AU - Liu, Guodong AU - Xu, Xiwei AU - He, Lihua AU - Ding, Zhaolu AU - Gu, Yixin AU - Zhang, Jianzhong AU - Zhou, Liya AD - National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing Y1 - 2011/10// PY - 2011 DA - Oct 2011 SP - 356 EP - 362 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 16 IS - 5 SN - 1083-4389, 1083-4389 KW - Microbiology Abstracts B: Bacteriology KW - Helicobacter pylori KW - Metronidazole KW - Amoxicillin KW - rRNA 23S KW - Levofloxacin KW - Drug resistance KW - Point mutation KW - Quinolones KW - DNA topoisomerase KW - Biopsy KW - Antibiotics KW - Tetracyclines KW - Children KW - Gentamicin KW - Clarithromycin KW - Rifampin KW - rRNA KW - Moxifloxacin KW - Azithromycin KW - Antibiotic resistance KW - Hospitals KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1328507438?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Helicobacter&rft.atitle=Primary+Antibiotic+Resistance+of+Helicobacter+pylori+Isolated+from+Beijing+Children&rft.au=Liu%2C+Guodong%3BXu%2C+Xiwei%3BHe%2C+Lihua%3BDing%2C+Zhaolu%3BGu%2C+Yixin%3BZhang%2C+Jianzhong%3BZhou%2C+Liya&rft.aulast=Liu&rft.aufirst=Guodong&rft.date=2011-10-01&rft.volume=16&rft.issue=5&rft.spage=356&rft.isbn=&rft.btitle=&rft.title=Helicobacter&rft.issn=10834389&rft_id=info:doi/10.1111%2Fj.1523-5378.2011.00856.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-04-01 N1 - Document feature - figure 0 N1 - Last updated - 2013-05-17 N1 - SubjectsTermNotLitGenreText - Metronidazole; Amoxicillin; rRNA 23S; Drug resistance; Levofloxacin; Quinolones; Point mutation; DNA topoisomerase; Antibiotics; Biopsy; Children; Tetracyclines; Gentamicin; rRNA; Rifampin; Clarithromycin; Moxifloxacin; Azithromycin; Antibiotic resistance; Hospitals; Helicobacter pylori DO - http://dx.doi.org/10.1111/j.1523-5378.2011.00856.x ER - TY - JOUR T1 - Taxonomy for strengthening the identification of core elements for evidence-based behavioral interventions for HIV/AIDS prevention AN - 1023093605; 201214504 AB - The concept of core elements was developed to denote characteristics of an intervention, such as activities or delivery methods, presumed to be responsible for the efficacy of evidence-based behavioral interventions (EBIs) for HIV/AIDS prevention. This paper describes the development of a taxonomy of core elements based on a literature review of theoretical approaches and characteristics of EBIs. Sixty-one categories of core elements were identified from the literature and grouped into three distinct domains: implementation, content and pedagogy. The taxonomy was tested by categorizing core elements from 20 HIV prevention EBIs disseminated by Centers for Disease Control and Prevention. Results indicated that core elements represented all three domains but several were difficult to operationalize due to vague language or the inclusion of numerous activities or constructs. A process is proposed to describe core elements in a method that overcomes some of these challenges. The taxonomy of core elements can be used to identify core elements of EBIs, strengthen the translation of EBIs from research to practice and guide future research seeking to identify essential core elements in prevention interventions. Adapted from the source document. JF - Health Education Research AU - Galbraith, Jennifer S AU - Herbst, Jeffrey H AU - Whittier, David K AU - Jones, Patricia L AU - Smith, Bryce D AU - Uhl, Gary AU - Fisher, Holly H AD - Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA jgalbraith@cdc.gov Y1 - 2011/10// PY - 2011 DA - October 2011 SP - 872 EP - 885 PB - Oxford University Press, UK VL - 26 IS - 5 SN - 0268-1153, 0268-1153 KW - Evidence based KW - Classification KW - Interventions KW - Preventive health care KW - HIV KW - Preventive programmes KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1023093605?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+Education+Research&rft.atitle=Taxonomy+for+strengthening+the+identification+of+core+elements+for+evidence-based+behavioral+interventions+for+HIV%2FAIDS+prevention&rft.au=Galbraith%2C+Jennifer+S%3BHerbst%2C+Jeffrey+H%3BWhittier%2C+David+K%3BJones%2C+Patricia+L%3BSmith%2C+Bryce+D%3BUhl%2C+Gary%3BFisher%2C+Holly+H&rft.aulast=Galbraith&rft.aufirst=Jennifer&rft.date=2011-10-01&rft.volume=26&rft.issue=5&rft.spage=872&rft.isbn=&rft.btitle=&rft.title=Health+Education+Research&rft.issn=02681153&rft_id=info:doi/10.1093%2Fher%2Fcyr030 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2012-07-01 N1 - Last updated - 2016-09-27 N1 - CODEN - HRTPE2 N1 - SubjectsTermNotLitGenreText - HIV; Classification; Interventions; Evidence based; Preventive health care; Preventive programmes DO - http://dx.doi.org/10.1093/her/cyr030 ER - TY - JOUR T1 - Quit Attempt Correlates among Smokers by Race/Ethnicity AN - 1020840159; 16435146 AB - Introduction: Cigarette smoking is the leading preventable cause of premature deaths in the U.S., accounting for approximately 443,000 deaths annually. Although smoking prevalence in recent decades has declined substantially among all racial/ethnic groups, disparities in smoking-related behaviors among racial/ethnic groups continue to exist. Two of the goals of Healthy People 2020 are to reduce smoking prevalence among adults to 12% or less and to increase smoking cessation attempts by adult smokers from 41% to 80%. Our study assesses whether correlates of quit attempts vary by race/ethnicity among adult ( greater than or equal to 18 years) smokers in the U.S. Understanding racial/ethnic differences in how both internal and external factors affect quit attempts is important for targeting smoking-cessation interventions to decrease tobacco-use disparities. Methods: We used 2003 Tobacco Use Supplement to the Current Population Survey (CPS) data from 16,213 adults to examine whether the relationship between demographic characteristics, smoking behaviors, smoking policies and having made a quit attempt in the past year varied by race/ethnicity. Results: Hispanics and persons of multiple races were more likely to have made a quit attempt than whites. Overall, younger individuals and those with >high school education, who smoked fewer cigarettes per day and had smoked for fewer years were more likely to have made a quit attempt. Having a smoke-free home, receiving a doctor's advice to quit, smoking menthol cigarettes and having a greater time to when you smoked your first cigarette of the day were also associated with having made a quit attempt. The relationship between these four variables and quit attempts varied by race/ethnicity; most notably receiving a doctor's advice was not related to quit attempts among Asian American/Pacific Islanders and menthol use among whites was associated with a lower prevalence of quit attempts while black menthol users were more likely to have made a quit attempt than white non-menthol users. Conclusions: Most correlates of quit attempts were similar across all racial/ethnic groups. Therefore population-based comprehensive tobacco control programs that increase quit attempts and successful cessation among all racial/ethnic groups should be continued and expanded. Additional strategies may be needed to encourage quit attempts among less educated, older, and more addicted smokers. JF - International Journal of Environmental Research and Public Health AU - Kahende, J W AU - Malarcher, A M AU - Teplinskaya, A AU - Asman, K J AD - Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health, 4770 Buford Highway, Atlanta, GA 30341, USA Y1 - 2011/10// PY - 2011 DA - Oct 2011 SP - 3871 EP - 3888 VL - 8 IS - 10 SN - 1660-4601, 1660-4601 KW - Health & Safety Science Abstracts KW - demography KW - Mortality KW - USA KW - Education KW - intervention KW - Cigarette smoking KW - Tobacco KW - Intervention KW - Ethnic groups KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1020840159?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Environmental+Research+and+Public+Health&rft.atitle=Quit+Attempt+Correlates+among+Smokers+by+Race%2FEthnicity&rft.au=Kahende%2C+J+W%3BMalarcher%2C+A+M%3BTeplinskaya%2C+A%3BAsman%2C+K+J&rft.aulast=Kahende&rft.aufirst=J&rft.date=2011-10-01&rft.volume=8&rft.issue=10&rft.spage=3871&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Environmental+Research+and+Public+Health&rft.issn=16604601&rft_id=info:doi/10.3390%2Fijerph8103871 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-06-01 N1 - Last updated - 2013-06-28 N1 - SubjectsTermNotLitGenreText - demography; Mortality; Education; intervention; Cigarette smoking; Tobacco; Intervention; Ethnic groups; USA DO - http://dx.doi.org/10.3390/ijerph8103871 ER - TY - JOUR T1 - Injuries to hired crop workers in the United States-a descriptive analysis of a national probability survey AN - 1017960278; 16691513 AB - Background Little empirical data are available examining the injury experience of hired crop workers in the United States (US). This study analyzed work-related injury data collected on these workers from a national survey. Methods Data were collected through the National Agricultural Workers Survey (NAWS) for the federal fiscal years 1999, 2002, 2003, and 2004. These data provided descriptive injury characteristics and rate estimates from a sample of 13,604 crop farm workers. Results The injury rate was 4.3 injuries per 100 week-based full-time equivalents (FTEWB). The majority of the injuries occurred to male (84%) and Mexican born (72%) workers. Shuttle migrants had the highest injury rate at 7.2 injuries/100 FTEWB. Workers reporting one or more health conditions and workers reporting one or more musculoskeletal complaints had higher injury. The most common injury events were overexertion from lifting (20%), being struck by hand held objects (13%), and falls to a lower level (10%). Injuries due to falls to a lower level accounted for the highest average number of restricted workdays (45 days). Conclusions The use of hand tools, falls, and lifting overexertion injuries were identified as significant causes of injury among hired crop workers. Increased injury risk was also seen for crop workers with existing health or musculoskeletal complaints. These results are useful for targeting injury prevention efforts and future research needs for this unique worker population. Am. J. Ind. Med. 54:734-747, 2011. ? 2011 Wiley-Liss, Inc. JF - American Journal of Industrial Medicine AU - Wang, Shuhui AU - Myers, John R AU - Layne, Larry A Y1 - 2011/10// PY - 2011 DA - Oct 2011 SP - 734 EP - 747 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 54 IS - 10 SN - 1097-0274, 1097-0274 KW - Risk Abstracts; Health & Safety Science Abstracts KW - USA KW - Injuries KW - migrants KW - farms KW - prevention KW - lifting KW - Crops KW - musculoskeletal system KW - hand tools KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1017960278?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Injuries+to+hired+crop+workers+in+the+United+States-a+descriptive+analysis+of+a+national+probability+survey&rft.au=Wang%2C+Shuhui%3BMyers%2C+John+R%3BLayne%2C+Larry+A&rft.aulast=Wang&rft.aufirst=Shuhui&rft.date=2011-10-01&rft.volume=54&rft.issue=10&rft.spage=734&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=10970274&rft_id=info:doi/10.1002%2Fajim.20980 L2 - http://onlinelibrary.wiley.com/doi/10.1002/ajim.20980/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2013-08-12 N1 - SubjectsTermNotLitGenreText - migrants; Injuries; farms; prevention; lifting; hand tools; musculoskeletal system; Crops; USA DO - http://dx.doi.org/10.1002/ajim.20980 ER - TY - JOUR T1 - Surveillance for waterborne disease outbreaks and other health events associated with recreational water --- United States, 2007--2008. AN - 893978196; 21937976 AB - Since 1978, CDC, the U.S. Environmental Protection Agency, and the Council of State and Territorial Epidemiologists have collaborated on the Waterborne Disease and Outbreak Surveillance System (WBDOSS) for collecting and reporting data on waterborne disease outbreaks associated with recreational water. This surveillance system is the primary source of data concerning the scope and health effects of waterborne disease outbreaks in the United States. In addition, data are collected on other select recreational water--associated health events, including pool chemical--associated health events and single cases of Vibrio wound infection and primary amebic meningoencephalitis (PAM). Data presented summarize recreational water--associated outbreaks and other health events that occurred during January 2007--December 2008. Previously unreported data on outbreaks that have occurred since 1978 also are presented. The WBDOSS database includes data on outbreaks associated with recreational water, drinking water, water not intended for drinking (excluding recreational water), and water use of unknown intent. Public health agencies in the states, the District of Columbia, U.S. territories, and Freely Associated States are primarily responsible for detecting and investigating waterborne disease outbreaks and voluntarily reporting them to CDC using a standard form. Only data on outbreaks associated with recreational water are summarized in this report. Data on other recreational water--associated health events reported to CDC, the Agency for Toxic Substances and Disease Registry (ATSDR), and the U.S. Consumer Product Safety Commission (CPSC) also are summarized. A total of 134 recreational water--associated outbreaks were reported by 38 states and Puerto Rico for 2007--2008. These outbreaks resulted in at least 13,966 cases. The median outbreak size was 11 cases (range: 2--5,697 cases). A total of 116 (86.6%) outbreaks were associated with treated recreational water (e.g., pools and interactive fountains) and resulted in 13,480 (96.5%) cases. Of the 134 outbreaks, 81 (60.4%) were outbreaks of acute gastrointestinal illness (AGI); 24 (17.9%) were outbreaks of dermatologic illnesses, conditions, or symptoms; and 17 (12.7%) were outbreaks of acute respiratory illness. Outbreaks of AGI resulted in 12,477 (89.3%) cases. The etiology was laboratory-confirmed for 105 (78.4%) of the 134 outbreaks. Of the 105 outbreaks with a laboratory-confirmed etiology, 68 (64.8%) were caused by parasites, 22 (21.0%) by bacteria, five (4.8%) by viruses, nine (8.6%) by chemicals or toxins, and one (1.0%) by multiple etiology types. Cryptosporidium was confirmed as the etiologic agent of 60 (44.8%) of 134 outbreaks, resulting in 12,154 (87.0%) cases; 58 (96.7%) of these outbreaks, resulting in a total of 12,137 (99.9%) cases, were associated with treated recreational water. A total of 32 pool chemical--associated health events that occurred in a public or residential setting were reported to WBDOSS by Maryland and Michigan. These events resulted in 48 cases of illness or injury; 26 (81.3%) events could be attributed at least partially to chemical handling errors (e.g., mixing incompatible chemicals). ATSDR's Hazardous Substance Emergency Events Surveillance System received 92 reports of hazardous substance events that occurred at aquatic facilities. More than half of these events (55 [59.8%]) involved injured persons; the most frequently reported primary contributing factor was human error. Estimates based on CPSC's National Electronic Injury Surveillance System (NEISS) data indicate that 4,574 (95% confidence interval [CI]: 2,703--6,446) emergency department (ED) visits attributable to pool chemical--associated injuries occurred in 2008; the most frequent diagnosis was poisoning (1,784 ED visits [95% CI: 585--2,984]). NEISS data indicate that pool chemical--associated health events occur frequently in residential settings. A total of 236 Vibrio wound infections were reported to be associated with recreational water exposure; 36 (48.6%) of the 74 hospitalized vibriosis patients and six (66.7%) of the nine vibriosis patients who died had V. vulnificus infections. Eight fatal cases of PAM occurred after exposure to warm untreated freshwater. The 134 recreational water--associated outbreaks reported for 2007--2008 represent a substantial increase over the 78 outbreaks reported for 2005--2006 and the largest number of outbreaks ever reported to WBDOSS for a 2-year period. Outbreaks, especially the largest ones, were most frequently associated with treated recreational water and characterized by AGI. Cryptosporidium remains the leading etiologic agent. Pool chemical--associated health events occur frequently but are preventable. Data on other select recreational water--associated health events further elucidate the epidemiology of U.S. waterborne disease by highlighting less frequently implicated types of recreational water (e.g., oceans) and detected types of recreational water--associated illness (i.e., not AGI). CDC uses waterborne disease outbreak surveillance data to 1) identify the types of etiologic agents, recreational water venues, and settings associated with waterborne disease outbreaks; 2) evaluate the adequacy of regulations and public awareness activities to promote healthy and safe swimming; and 3) establish public health priorities to improve prevention efforts, guidelines, and regulations at the local, state, and federal levels. JF - Morbidity and mortality weekly report. Surveillance summaries (Washington, D.C. : 2002) AU - Hlavsa, Michele C AU - Roberts, Virginia A AU - Anderson, Ayana R AU - Hill, Vincent R AU - Kahler, Amy M AU - Orr, Maureen AU - Garrison, Laurel E AU - Hicks, Lauri A AU - Newton, Anna AU - Hilborn, Elizabeth D AU - Wade, Timothy J AU - Beach, Michael J AU - Yoder, Jonathan S AU - CDC AD - Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, CDC, Atlanta, GA 30333, USA. healthywater@cdc.gov ; CDC Y1 - 2011/09/23/ PY - 2011 DA - 2011 Sep 23 SP - 1 EP - 32 VL - 60 IS - 12 KW - Index Medicus KW - Acute Disease KW - Swimming KW - Humans KW - Child KW - Cryptosporidium -- isolation & purification KW - Child, Preschool KW - Infant KW - Swimming Pools KW - Cryptosporidiosis KW - Adult KW - Middle Aged KW - Adolescent KW - United States -- epidemiology KW - Female KW - Male KW - Recreation KW - Gastrointestinal Diseases -- parasitology KW - Gastrointestinal Diseases -- microbiology KW - Gastrointestinal Diseases -- virology KW - Disease Outbreaks KW - Water Microbiology KW - Gastrointestinal Diseases -- epidemiology KW - Population Surveillance UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/893978196?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Morbidity+and+mortality+weekly+report.+Surveillance+summaries+%28Washington%2C+D.C.+%3A+2002%29&rft.atitle=Surveillance+for+waterborne+disease+outbreaks+and+other+health+events+associated+with+recreational+water+---+United+States%2C+2007--2008.&rft.au=Hlavsa%2C+Michele+C%3BRoberts%2C+Virginia+A%3BAnderson%2C+Ayana+R%3BHill%2C+Vincent+R%3BKahler%2C+Amy+M%3BOrr%2C+Maureen%3BGarrison%2C+Laurel+E%3BHicks%2C+Lauri+A%3BNewton%2C+Anna%3BHilborn%2C+Elizabeth+D%3BWade%2C+Timothy+J%3BBeach%2C+Michael+J%3BYoder%2C+Jonathan+S%3BCDC&rft.aulast=Hlavsa&rft.aufirst=Michele&rft.date=2011-09-23&rft.volume=60&rft.issue=12&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Morbidity+and+mortality+weekly+report.+Surveillance+summaries+%28Washington%2C+D.C.+%3A+2002%29&rft.issn=1545-8636&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-10-28 N1 - Date created - 2011-09-22 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Erratum In: MMWR Surveill Summ. 2011 Oct 14;60(40):1395 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Hepatitis B vaccination coverage among high-risk adults 18-49 years, U.S., 2009 AN - 899158391; 15705335 AB - Approximately 43,000 new hepatitis B virus (HBV) infections occurred in 2007. Although hepB vaccination has been recommended for adults at high-risk for incident HBV infection for many years, coverage remains low. Methods: We used the 2009 National Health Interview Survey to assess self-reported HepB vaccine uptake (=1 dose), series completion (=3 dose), and independent predictors of vaccination among high-risk adults aged 18-49 years. High-risk adults were defined as those reporting male sex with men; injection drug use; hemophilia with receipt of clotting factors; sexually transmitted disease in prior five years; sex for money or drugs; HIV positive; sex with persons having any above risk factors; or who "felt they were at high risk for HIV". Persons with none of the aforementioned risk factors were considered non-high risk. Bivariate analysis was conducted to assess vaccination coverage. Independent predictors of vaccine uptake and series completion were determined using a logistic regression. Results: Overall, 7.0% adults aged 18-49 years had high-risk behaviors. Unadjusted coverage with =1 dose was 50.5% among high-risk compared to 40.5% among non-high-risk adults (p-values 0.001) while series completion (=3 doses) was 41.8% and 34.2%, respectively (p-values 0.001). On multivariable analysis, =1 dose coverage, but not series completion, was higher (Risk Ratio 1.1, 95% CI = 1.0-1.2, p-value = 0.021) among high-risk compared to non-high risk adults. Other characteristics independently associated with a higher likelihood of HepB vaccination among persons 18-49 years included younger age groups, females, higher education, =2 physician contacts in the past year, ever tested for HIV, health care personnel, received influenza vaccination in the previous year, and ever received hepatitis A vaccination. Vaccine uptake with =1 dose increased by 5.1% (p = 0.047) among high-risk adults between 2004 and 2009. Conclusions: A small increase in =1 dose HepB vaccination coverage among high-risk adults compared with non-high risk adults was documented for the first time in 2009. Higher coverage among persons 18-30 years may reflect aging of persons vaccinated when they were children and adolescents. To improve protection against hepatitis B among high-risk adults, healthcare providers should offer hepatitis B vaccination to persons at high risk and those who seek vaccination to protect themselves and facilitate timely completion of the three (3) dose HepB series. JF - Vaccine AU - Lu, Peng-Jun AU - Byrd, Kathy K AU - Murphy, Trudy V AU - Weinbaum, Cindy Y1 - 2011/09/16/ PY - 2011 DA - 2011 Sep 16 SP - 7049 EP - 7057 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 29 IS - 40 SN - 0264-410X, 0264-410X KW - Risk Abstracts; Virology & AIDS Abstracts; Health & Safety Science Abstracts; Immunology Abstracts KW - vaccines KW - Sexually-transmitted diseases KW - Aging KW - hepatitis B KW - Infection KW - Medical personnel KW - Influenza KW - Clotting KW - Personnel KW - Risk factors KW - infection KW - Hepatitis B KW - Hepatitis A KW - Risk groups KW - Drugs KW - sexually transmitted diseases KW - Adolescents KW - Sex KW - Hepatitis B virus KW - Adolescence KW - Children KW - Vaccination KW - Hemophilia KW - USA KW - Education KW - Human immunodeficiency virus KW - Vaccines KW - V 22360:AIDS and HIV KW - F 06905:Vaccines KW - R2 23060:Medical and environmental health KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/899158391?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Hepatitis+B+vaccination+coverage+among+high-risk+adults+18-49+years%2C+U.S.%2C+2009&rft.au=Lu%2C+Peng-Jun%3BByrd%2C+Kathy+K%3BMurphy%2C+Trudy+V%3BWeinbaum%2C+Cindy&rft.aulast=Lu&rft.aufirst=Peng-Jun&rft.date=2011-09-16&rft.volume=29&rft.issue=40&rft.spage=7049&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/10.1016%2Fj.vaccine.2011.07.030 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - Sexually-transmitted diseases; Adolescence; Aging; Infection; Children; Vaccination; Hemophilia; Influenza; Education; Clotting; Personnel; Risk factors; Hepatitis B; Risk groups; Hepatitis A; Vaccines; Drugs; Sex; vaccines; Human immunodeficiency virus; infection; hepatitis B; Adolescents; sexually transmitted diseases; Medical personnel; Hepatitis B virus; USA DO - http://dx.doi.org/10.1016/j.vaccine.2011.07.030 ER - TY - JOUR T1 - Relationship between pulmonary and systemic markers of exposure to multiple types of welding particulate matter AN - 899153500; 15553668 AB - Welding results in a unique and complex occupational exposure. Recent epidemiological studies have shown an increased risk of cardiovascular disease following welding fume exposure. In this study, we compared the induction of pulmonary and systemic inflammation following exposure to multiple types of welding fumes. Mice were exposed to 340 mu g of manual metal arc stainless steel (MMA-SS), gas metal arc-SS (GMA-SS) or GMA-mild steel (GMA-MS) by pharyngeal aspiration. Mice were sacrificed at 4 and 24h post-exposure to evaluate various parameters of pulmonary and systemic inflammation. Alterations in pulmonary gene expression by a custom designed TaqMan array showed minimal differences between the fumes at 4h. Conversely at 24h, gene expression changes were further increased by SS but not GMA-MS exposure.These findings were associated with the surrogate marker of systemic inflammation, liver acute phase gene induction. Interestingly, stress response genes in cardiovascular tissues were only increased following MMA-SS exposure. These effects were related to the initial level of pulmonary cytotoxicity, as measured by lactate dehydrogenase activity, which was greatest following MMA-SS exposure. In conclusion, varying types of welding fumes elicit quantitatively different systemic inflammatory and/or stress responses. JF - Toxicology AU - Erdely, Aaron AU - Salmen-Muniz, Rebecca AU - Liston, Angie AU - Hulderman, Tracy AU - Zeidler-Erdely, Patti C AU - Antonini, James M AU - Simeonova, Petia P Y1 - 2011/09/05/ PY - 2011 DA - 2011 Sep 05 SP - 153 EP - 159 PB - Elsevier B.V., P.O. Box 85 Limerick Ireland VL - 287 IS - 1-3 SN - 0300-483X, 0300-483X KW - Health & Safety Science Abstracts; Toxicology Abstracts KW - Pharynx KW - Particulate matter KW - Gene expression KW - Welding KW - Steel KW - Occupational exposure KW - Metals KW - Fumes KW - Stress KW - Mice KW - Inflammation KW - L-Lactate dehydrogenase KW - Cytotoxicity KW - Lung KW - Liver KW - Cardiovascular diseases KW - stainless steel KW - H 1000:Occupational Safety and Health KW - X 24360:Metals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/899153500?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology&rft.atitle=Relationship+between+pulmonary+and+systemic+markers+of+exposure+to+multiple+types+of+welding+particulate+matter&rft.au=Erdely%2C+Aaron%3BSalmen-Muniz%2C+Rebecca%3BListon%2C+Angie%3BHulderman%2C+Tracy%3BZeidler-Erdely%2C+Patti+C%3BAntonini%2C+James+M%3BSimeonova%2C+Petia+P&rft.aulast=Erdely&rft.aufirst=Aaron&rft.date=2011-09-05&rft.volume=287&rft.issue=1-3&rft.spage=153&rft.isbn=&rft.btitle=&rft.title=Toxicology&rft.issn=0300483X&rft_id=info:doi/10.1016%2Fj.tox.2011.06.008 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Metals; Pharynx; Fumes; Particulate matter; Stress; L-Lactate dehydrogenase; Inflammation; Gene expression; Cytotoxicity; Lung; Liver; Welding; Cardiovascular diseases; Steel; Occupational exposure; stainless steel; Mice DO - http://dx.doi.org/10.1016/j.tox.2011.06.008 ER - TY - JOUR T1 - Reversing the tide of obesity AN - 899158496; 15704327 JF - Lancet AU - Dietz, William H Y1 - 2011/09/02/ PY - 2011 DA - 2011 Sep 02 SP - 744 EP - 746 PB - The Lancet Ltd., 655 Ave. of the Americas New York NY 10011 United States VL - 378 IS - 9793 SN - 0140-6736, 0140-6736 KW - Health & Safety Science Abstracts KW - obesity KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/899158496?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Lancet&rft.atitle=Reversing+the+tide+of+obesity&rft.au=Dietz%2C+William+H&rft.aulast=Dietz&rft.aufirst=William&rft.date=2011-09-02&rft.volume=378&rft.issue=9793&rft.spage=744&rft.isbn=&rft.btitle=&rft.title=Lancet&rft.issn=01406736&rft_id=info:doi/10.1016%2FS0140-6736%2811%2961218-X LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Last updated - 2013-02-08 N1 - SubjectsTermNotLitGenreText - obesity DO - http://dx.doi.org/10.1016/S0140-6736(11)61218-X ER - TY - JOUR T1 - Maternal injuries during the periconceptional period and the risk of birth defects, National Birth Defects Prevention Study, 1997-2005 AN - 899166048; 15734578 AB - Tinker SC, Reefhuis J, Dellinger AM, Jamieson DJ, the National Birth Defects Prevention Study. Maternal injuries during the periconceptional period and the risk of birth defects, National Birth Defects Prevention Study, 1997-2005. Paediatric and Perinatal Epidemiology 2011; 25: 487-496. Maternal injuries during pregnancy are common ( similar to 7% prevalence). However, few studies have examined the association between maternal injuries and birth defects. The National Birth Defects Prevention Study is a population-based case-control study of birth defects in 10 US states. Cases were ascertained through surveillance; controls were randomly selected from infants delivered without major birth defects in the study regions. Mothers completed a telephone interview on exposures before and during pregnancy, including injuries. We assessed associations between periconceptional (month before until the end of the third month of pregnancy) maternal injuries and birth defects. We used logistic regression to estimate adjusted odds ratios (AORs) and 95% confidence intervals (CI). Periconceptional injuries were associated with interrupted aortic arch type B [AOR=5.2, 95% CI 1.2, 23.2]; atrioventricular septal defect [AOR=2.2, 95% CI 1.1, 4.4]; pulmonary atresia [AOR=3.2, 95% CI 1.6, 6.4]; tricuspid atresia [AOR=2.8, 95% CI 1.2, 6.7]; hypoplastic left heart syndrome [AOR=2.0, 95% CI 1.1, 3.4]; anorectal atresia/stenosis [AOR=1.7, 95% CI 1.0, 2.7]; longitudinal limb deficiency [AOR=2.1, 95% CI 1.1, 3.9]; and gastroschisis [AOR=1.8, 95% CI 1.2, 2.8]. Associations with longitudinal limb deficiency, gastroschisis and hypoplastic left heart syndrome were stronger for intentional injuries. Our results suggest maternal injury during the periconceptional period, particularly those inflicted intentionally, may be associated with select birth defects. This analysis was hypothesis-generating, with many associations tested. Further research is warranted. JF - Paediatric and Perinatal Epidemiology AU - Tinker, Sarah C AU - Reefhuis, Jennita AU - Dellinger, Ann M AU - Jamieson, Denise J AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention (CDC) Y1 - 2011/09// PY - 2011 DA - Sep 2011 SP - 487 EP - 496 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 25 IS - 5 SN - 0269-5022, 0269-5022 KW - Risk Abstracts KW - Congenital defects KW - Infants KW - Injuries KW - Pregnancy KW - prevention KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/899166048?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Paediatric+and+Perinatal+Epidemiology&rft.atitle=Maternal+injuries+during+the+periconceptional+period+and+the+risk+of+birth+defects%2C+National+Birth+Defects+Prevention+Study%2C+1997-2005&rft.au=Tinker%2C+Sarah+C%3BReefhuis%2C+Jennita%3BDellinger%2C+Ann+M%3BJamieson%2C+Denise+J&rft.aulast=Tinker&rft.aufirst=Sarah&rft.date=2011-09-01&rft.volume=25&rft.issue=5&rft.spage=487&rft.isbn=&rft.btitle=&rft.title=Paediatric+and+Perinatal+Epidemiology&rft.issn=02695022&rft_id=info:doi/10.1111%2Fj.1365-3016.2011.01215.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Document feature - figure 1 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - Injuries; prevention; Congenital defects; Infants; Pregnancy DO - http://dx.doi.org/10.1111/j.1365-3016.2011.01215.x ER - TY - JOUR T1 - Efficacy of the Revised NIOSH Lifting Equation to Predict Risk of Low Back Pain Due to Manual Lifting Expanded Cross-Sectional Analysis AN - 899164280; 15775772 AB - Objective: To evaluate whether the Revised NIOSH Lifting Equation (RNLE) is a valid tool for assessing risk of low back pain (LBP) due to manual lifting by using combined data from two cross-sectional studies of 1-year prevalence. Methods: Results from a symptom and occupational history questionnaire and RNLE analysis for 677 subjects employed in 125 manual lifting jobs at nine industrial sites were combined from two studies. Results: The odds of LBP increased as the lifting index (LI) increased from 1.0 to 3.0. A statistically significant odds ratio (OR) was found for both the 1 < LI less than or equal to 2 (OR = 1.81) and the 2 < LI less than or equal to 3 categories (OR = 2.26). For jobs with an LI value greater than 3.0, however, the OR remained nonsignificant. The 2 < LI less than or equal to 3 group remained statistically significant after adjusting for age, gender, body mass index, and psychosocial factors. Conclusions: It is clear that as the LI increases, the risk of LBP increases. Longitudinal studies are needed. JF - Journal of Occupational and Environmental Medicine AU - Waters, T R AU - Lu, M-L AU - Piacitelli, LA AU - Werren, D AU - Deddens, JA AD - NIOSH (C24), 4676 Columbia Parkway, Cincinnati, OH 45226, USA, trw1@cdc.gov Y1 - 2011/09// PY - 2011 DA - Sep 2011 SP - 1061 EP - 1067 VL - 53 IS - 9 SN - 1076-2752, 1076-2752 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Historical account KW - Age KW - low back pain KW - body mass KW - Gender KW - lifting KW - longitudinal studies KW - H 1000:Occupational Safety and Health KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/899164280?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Efficacy+of+the+Revised+NIOSH+Lifting+Equation+to+Predict+Risk+of+Low+Back+Pain+Due+to+Manual+Lifting+Expanded+Cross-Sectional+Analysis&rft.au=Waters%2C+T+R%3BLu%2C+M-L%3BPiacitelli%2C+LA%3BWerren%2C+D%3BDeddens%2C+JA&rft.aulast=Waters&rft.aufirst=T&rft.date=2011-09-01&rft.volume=53&rft.issue=9&rft.spage=1061&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e31822cfe5e LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Historical account; Age; body mass; Gender; low back pain; lifting; longitudinal studies DO - http://dx.doi.org/10.1097/JOM.0b013e31822cfe5e ER - TY - JOUR T1 - Adverse childhood experiences and smoking status in five states AN - 899161401; 15724354 AB - Objective: Our objective was to examine the associations between adverse childhood experiences (ACEs) and smoking behavior among a random sample of adults living in five U.S. states. Methods: We used data from 25,809 participants of the 2009 Behavioral Risk Factor Surveillance System to assess the relationship of each of the 8 adverse childhood experiences and the adverse childhood experience score to smoking status. Results and conclusions: Some 59.4% of men and women reported at least one adverse childhood experience. Each of the eight adverse childhood experiences measures was significantly associated with smoking status after adjustment for demographic variables. The prevalence ratios for current and ever smoking increased in a positive graded fashion as the adverse childhood experience score increased. Among adults who reported no adverse childhood experiences, 13.0% were currently smoking and 38.3% had ever smoked. Compared to participants with an adverse childhood experience score of 0, those with an adverse childhood experience score of 5 or more were more likely to be a current smoker (adjusted prevalence ratio (aPR): 2.22, 95% confidence interval [CI]: 1.92-2.57) and to have ever smoked (aPR: 1.80, 95% CI: 1.67-1.93). Further research is warranted to determine whether the prevention of and interventions for adverse childhood experiences might reduce the burden of smoking-related illness in the general population. JF - Preventive Medicine AU - Ford, Earl S AU - Anda, Robert F AU - Edwards, Valerie J AU - Perry, Geraldine S AU - Zhao, Guixiang AU - Li, Chaoyang AU - Croft, Janet B Y1 - 2011/09/01/ PY - 2011 DA - 2011 Sep 01 SP - 188 EP - 193 PB - Elsevier B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 53 IS - 3 SN - 0091-7435, 0091-7435 KW - Risk Abstracts KW - demography KW - Children KW - Smoking KW - USA KW - intervention KW - Risk factors KW - prevention KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/899161401?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Preventive+Medicine&rft.atitle=Adverse+childhood+experiences+and+smoking+status+in+five+states&rft.au=Ford%2C+Earl+S%3BAnda%2C+Robert+F%3BEdwards%2C+Valerie+J%3BPerry%2C+Geraldine+S%3BZhao%2C+Guixiang%3BLi%2C+Chaoyang%3BCroft%2C+Janet+B&rft.aulast=Ford&rft.aufirst=Earl&rft.date=2011-09-01&rft.volume=53&rft.issue=3&rft.spage=188&rft.isbn=&rft.btitle=&rft.title=Preventive+Medicine&rft.issn=00917435&rft_id=info:doi/10.1016%2Fj.ypmed.2011.06.015 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - demography; Smoking; Risk factors; intervention; prevention; Children; USA DO - http://dx.doi.org/10.1016/j.ypmed.2011.06.015 ER - TY - JOUR T1 - Cigarettes Smoked per Day Among High School Students in the U.S., 1991-2009 AN - 893275449; 15592896 AB - Nationally representative data from the 1991-2009 national Youth Risk Behavior Surveys (YRBS) were analyzed in 2010. The YRBS is a biennial, school-based survey representative of 9th- through 12th-grade students in the U.S. Each survey year, students completed anonymous, self-administered questionnaires that included identically worded questions about cigarette use. The number of cigarettes smoked per day on smoking days was categorized as light smoking (1-5 cigarettes per day); moderate smoking (6-10 cigarettes per day); and heavy smoking (=11 cigarettes per day). Sample sizes ranged from 10,904 to 16,410. Overall response rates ranged from 60% to 71%. Results: During 1991-2009, among current cigarette users overall, light smoking increased from 67.2% to 79.4% and heavy smoking decreased from 18.0% to 7.8%. These trends were found among female and male students overall and white students. Among Hispanic students, light smoking remained stable, but heavy smoking significantly increased from 3.1% in 1991 to 6.4% in 2009. The prevalence of light, moderate, and heavy smoking did not change during 1991-2009 among black students. Conclusions: The finding that during 1991-2009 light smoking increased and heavy smoking decreased among current cigarette users is encouraging; however, even light smoking is detrimental to health and efforts to reduce all cigarette use should continue. JF - American Journal of Preventive Medicine AU - Jones, Sherry E AU - Kann, Laura AU - Pechacek, Terry F Y1 - 2011/09// PY - 2011 DA - Sep 2011 SP - 297 EP - 299 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 41 IS - 3 SN - 0749-3797, 0749-3797 KW - Risk Abstracts KW - USA KW - Cigarettes KW - Adolescents KW - Ethnic groups KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/893275449?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Cigarettes+Smoked+per+Day+Among+High+School+Students+in+the+U.S.%2C+1991-2009&rft.au=Jones%2C+Sherry+E%3BKann%2C+Laura%3BPechacek%2C+Terry+F&rft.aulast=Jones&rft.aufirst=Sherry&rft.date=2011-09-01&rft.volume=41&rft.issue=3&rft.spage=297&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2011.05.018 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-09-01 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - Cigarettes; Ethnic groups; Adolescents; USA DO - http://dx.doi.org/10.1016/j.amepre.2011.05.018 ER - TY - JOUR T1 - The vibration transmissibility and driving-point biodynamic response of the hand exposed to vibration normal to the palm AN - 888111504; 15587025 AB - Prolonged, intensive exposure to vibrations from palm and orbital sanders could cause finger disorders. They are likely to be associated with the biodynamic responses of the fingers. Although the biodynamic responses of the hand-arm system have been studied by many researchers, the detailed biodynamic responses distributed in the hand substructures have not been sufficiently understood. To advance the knowledge in this aspect and to aid in the development of improved finite element models of the substructures, this study simultaneously measured the overall driving-point biodynamic response and the distribution of vibration transmissibility at the fingers and back of the hand exposed to a flat plate vibration (as an approximate simulation of the operations of the palm and orbital sanders) and examined the relationship between these two measures of biodynamic responses. ten subjects (five males and five females) participated in the experiment. A scanning laser vibrometer was used to measure the distributed vibration. This study confirmed that the distributed hand responses generally varied with locations on each finger, vibration frequencies, and applied hand force. Two major resonances were observed in the vibration transmissibility. At the first resonance, the transmitted vibrations at different locations were more or less in phase; hence, this resonance was also observed in the driving-point biodynamic response that measures the overall biodynamic response of the system. The second resonance was observed at the fingers. Because this resonant frequency varied greatly among the fingers and the specific segments of each finger, it is difficult to identify this resonance in the driving-point biodynamic response. The implications of the findings for further model developments and applications are discussed. Relevance to industry: This study enhanced the understanding of the biodynamic responses of the fingers and hand exposed to vibrations on a contact surface with a large effective radius such as that found on palm and orbital sanders. The results can also be used to develop and/or validate models of the substructures of the hand-arm system, which can be further used to help design and analyze these tools and associated anti-vibration devices. The results may also be applicable to help develop location-specific frequency weightings to assess the risks of the finger vibration exposure. JF - International Journal of Industrial Ergonomics AU - Xu, Xueyan S AU - Welcome, Daniel E AU - McDowell, Thomas W AU - Wu, John Z AU - Wimer, Bryan AU - Warren, Christopher AU - Dong, Ren G Y1 - 2011/09// PY - 2011 DA - Sep 2011 SP - 418 EP - 427 PB - Elsevier B.V., P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 41 IS - 5 SN - 0169-8141, 0169-8141 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Ergonomics KW - Vibration KW - H 10000:Ergonomics/Human Factors KW - R2 23010:General: Models, forecasting UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/888111504?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Industrial+Ergonomics&rft.atitle=The+vibration+transmissibility+and+driving-point+biodynamic+response+of+the+hand+exposed+to+vibration+normal+to+the+palm&rft.au=Xu%2C+Xueyan+S%3BWelcome%2C+Daniel+E%3BMcDowell%2C+Thomas+W%3BWu%2C+John+Z%3BWimer%2C+Bryan%3BWarren%2C+Christopher%3BDong%2C+Ren+G&rft.aulast=Xu&rft.aufirst=Xueyan&rft.date=2011-09-01&rft.volume=41&rft.issue=5&rft.spage=418&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Industrial+Ergonomics&rft.issn=01698141&rft_id=info:doi/10.1016%2Fj.ergon.2011.05.007 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-09-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Vibration DO - http://dx.doi.org/10.1016/j.ergon.2011.05.007 ER - TY - JOUR T1 - Mobilizing Communities and Building Capacity for Youth Violence Prevention: The National Academic Centers of Excellence for Youth Violence Prevention AN - 1417526877; 201334845 AB - Violence, including its occurrence among youth, results in considerable physical, emotional, social, and economic consequences in the US. Youth violence prevention work at the Division of Violence Prevention (DVP) at the Centers for Disease Control and Prevention (CDC) emphasizes preventing youth violence-related behaviors, injuries, and deaths by collaborating with academic and community partners and stakeholders. In 2000 and 2005, DVP funded the National Academic Centers of Excellence (ACE) for Youth Violence Prevention. Most ACE Centers focus on building community capacity and competence so that evidence-based programs for youth violence prevention can be successfully implemented through effective and supportive research-community partnerships. This commentary provides historical information about the ACE Program, including the development, goals, accomplishments of the Centers, and the utilization of a community-based participatory research approach to prevent youth violence. Adapted from the source document. JF - American Journal of Community Psychology AU - Vivolo, Alana M AU - Matjasko, Jennifer L AU - Massetti, Greta M AD - Division of Violence Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention Y1 - 2011/09// PY - 2011 DA - September 2011 SP - 141 EP - 145 PB - Springer, Dordrecht The Netherlands VL - 48 IS - 1-2 SN - 0091-0562, 0091-0562 KW - Development Programs KW - Prevention KW - Competence KW - Cooperation KW - United States of America KW - Academic Departments KW - Interest Groups KW - Youth KW - Health Care Services KW - article KW - 2317: community/regional development; sociology of communities & regions UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1417526877?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocabs&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Community+Psychology&rft.atitle=Mobilizing+Communities+and+Building+Capacity+for+Youth+Violence+Prevention%3A+The+National+Academic+Centers+of+Excellence+for+Youth+Violence+Prevention&rft.au=Vivolo%2C+Alana+M%3BMatjasko%2C+Jennifer+L%3BMassetti%2C+Greta+M&rft.aulast=Vivolo&rft.aufirst=Alana&rft.date=2011-09-01&rft.volume=48&rft.issue=1-2&rft.spage=141&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Community+Psychology&rft.issn=00910562&rft_id=info:doi/10.1007%2Fs10464-010-9419-5 LA - English DB - Sociological Abstracts N1 - Date revised - 2013-08-01 N1 - Last updated - 2016-09-28 N1 - CODEN - AJCPCK N1 - SubjectsTermNotLitGenreText - Youth; Prevention; Health Care Services; Competence; Interest Groups; Development Programs; Cooperation; Academic Departments; United States of America DO - http://dx.doi.org/10.1007/s10464-010-9419-5 ER - TY - JOUR T1 - Emerging issues in teratology: an introduction. AN - 878593941; 21766432 JF - American journal of medical genetics. Part C, Seminars in medical genetics AU - Rasmussen, Sonja A AU - Friedman, Jan M AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA. skr9@cdc.gov Y1 - 2011/08/15/ PY - 2011 DA - 2011 Aug 15 SP - 147 EP - 149 VL - 157C IS - 3 KW - Index Medicus KW - United States KW - United States Food and Drug Administration KW - Humans KW - Abnormalities, Drug-Induced -- metabolism KW - Teratology -- trends UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/878593941?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+journal+of+medical+genetics.+Part+C%2C+Seminars+in+medical+genetics&rft.atitle=Emerging+issues+in+teratology%3A+an+introduction.&rft.au=Rasmussen%2C+Sonja+A%3BFriedman%2C+Jan+M&rft.aulast=Rasmussen&rft.aufirst=Sonja&rft.date=2011-08-15&rft.volume=157C&rft.issue=3&rft.spage=147&rft.isbn=&rft.btitle=&rft.title=American+journal+of+medical+genetics.+Part+C%2C+Seminars+in+medical+genetics&rft.issn=1552-4876&rft_id=info:doi/10.1002%2Fajmg.c.30305 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-12-23 N1 - Date created - 2011-07-20 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1002/ajmg.c.30305 ER - TY - JOUR T1 - Molecular Typing of Salmonella Serotype O: 4(B) by Using Pulsed-field Gel Electrophoresis AN - 918056010; 16043045 AB - The objective of the present study was to document the polymorphism of PFGE molecular type of Salmonella enterica subsp. enterica serotype O: 4(B) which isolated from food-borne diseases and to explore theirs relationship of molecular epidemiological. In this research, 29 Salmonella stains were identified and the single colony was picked and enriched. Then the total genomic DNA of the isolates was digested with restriction enzyme Xba I, and run pulsed-field gel electrophoresis (PFGE). The DNA fingerprints of different stains were analyzed by Bionumerics5.1 software to perform clustering. The DNA fingerprints of 29 Salmonella were belonged to 24 PFGE pattern combinations. Similarity value of these strains was in the range of 56.31% similar to 100%. One serotype Salmonella could be found several PFGE pattern combinations. The PFGE technology is a good method for molecular typing of Salmonella serotype O: 4(B) and could be effectively apply on tracing the suspected source of food contamination and investigate the food-poisoning and also study the molecular epidemiological relationship of different Salmonella stains. JF - Genomics And Applied Biology AU - Wang, H AU - Huang, Y AU - Tang, Z AU - Sun, G AU - Li, X AU - Wei, C AD - Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning, 530028, huangyangx@163.com Y1 - 2011/08// PY - 2011 DA - Aug 2011 SP - 305 EP - 310 VL - 30 IS - 4 SN - 1674-568X, 1674-568X KW - Microbiology Abstracts B: Bacteriology KW - Serotypes KW - Food KW - Enzymes KW - Stains KW - Food contamination KW - Food-borne diseases KW - Computer programs KW - software KW - Colonies KW - Typing KW - Salmonella enterica KW - Pulsed-field gel electrophoresis KW - DNA KW - genomics KW - J 02310:Genetics & Taxonomy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/918056010?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Genomics+And+Applied+Biology&rft.atitle=Molecular+Typing+of+Salmonella+Serotype+O%3A+4%28B%29+by+Using+Pulsed-field+Gel+Electrophoresis&rft.au=Wang%2C+H%3BHuang%2C+Y%3BTang%2C+Z%3BSun%2C+G%3BLi%2C+X%3BWei%2C+C&rft.aulast=Wang&rft.aufirst=H&rft.date=2011-08-01&rft.volume=30&rft.issue=4&rft.spage=305&rft.isbn=&rft.btitle=&rft.title=Genomics+And+Applied+Biology&rft.issn=1674568X&rft_id=info:doi/10.3969%2Fgab.030.000305 LA - Chinese DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-01-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Serotypes; Food; Enzymes; Stains; Food contamination; Food-borne diseases; Computer programs; Colonies; software; Typing; DNA; Pulsed-field gel electrophoresis; genomics; Salmonella enterica DO - http://dx.doi.org/10.3969/gab.030.000305 ER - TY - JOUR T1 - Nonfatal bathroom injuries among persons aged greater than or equal to 15 years-United States, 2008 . AN - 904496041; 15938762 AB - Problem: Information about where nonfatal unintentional injuries occur is limited, but bathrooms commonly are believed to be a hazardous location. Methods: Data from a nationally representative sample of hospital emergency departments (ED) was used to quantify and characterize nonfatal unintentional bathroom injuries among people aged greater than or equal to 15 years. Results: In 2008, an estimated 234,094 nonfatal bathroom injuries were treated in EDs. Most injuries (81.1%) were caused by falls and 37.3% of injuries occurred when bathing, showering, or getting out of the tub or shower. Both injury and hospitalization rates increased with age. Summary: These results suggest that bathrooms tend to be most hazardous for persons in the oldest age groups. Impact on Industry: Bathroom injuries among all household members might be reduced by increasing awareness about potentially hazardous activities in the bathroom combined with simple environmental changes such as adding grab bars inside and outside the tub or shower. JF - Journal of Safety Research AU - Haas, Elizabeth N AU - Haileyesus, Tadesse AD - National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA, USA, jas2@cdc.gov Y1 - 2011/08// PY - 2011 DA - Aug 2011 SP - 311 EP - 315 PB - Elsevier B.V., P.O. Box 800 Kidlington Oxford OX5 1DX United Kingdom VL - 42 IS - 4 SN - 0022-4375, 0022-4375 KW - Health & Safety Science Abstracts KW - Age KW - Hospitals KW - Injuries KW - age groups KW - emergency medical services KW - environmental changes KW - households KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/904496041?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Safety+Research&rft.atitle=Nonfatal+bathroom+injuries+among+persons+aged+greater+than+or+equal+to+15+years-United+States%2C+2008+.&rft.au=Haas%2C+Elizabeth+N%3BHaileyesus%2C+Tadesse&rft.aulast=Haas&rft.aufirst=Elizabeth&rft.date=2011-08-01&rft.volume=42&rft.issue=4&rft.spage=311&rft.isbn=&rft.btitle=&rft.title=Journal+of+Safety+Research&rft.issn=00224375&rft_id=info:doi/10.1016%2Fj.jsr.2011.07.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2013-05-06 N1 - SubjectsTermNotLitGenreText - age groups; Age; households; Injuries; environmental changes; emergency medical services; Hospitals DO - http://dx.doi.org/10.1016/j.jsr.2011.07.001 ER - TY - JOUR T1 - Predictors of discordant tuberculin skin test and QuantiFERON registered -TB Gold In-Tube results in various high-risk groups AN - 893268447; 15631165 AB - SETTING: Persons in whom targeted testing for latent tuberculosis infection (LTBI) is recommended in Seattle, Washington; Atlanta, Georgia; and central North Carolina, United States. OBJECTIVE: To compare the performance of an inter-feron-gamma release assay (QuantiFERON registered -TB Gold In-Tube [QFT-GIT]) with the tuberculin skin test (TST) among foreign-born, homeless, human immunodeficiency virus (HIV) infected and substance abuse persons tested for LTBI. DESIGN: A cross-sectional study requiring participants to have a blood test, a TST and data collected. RESULTS: Of 1653 persons, 19.5% were TST-positive and 14.0% were QFT-GIT-positive. Overall concordance was moderate (kappa 0.53; 95%CI 0.47-0.58). Compared to concordant positive results, TST+/QFT-GIT-discordance was associated with HIV infection and sex, while TST-/QFT-GIT + discordance was associated with HIV and inversely associated with foreign birth. Compared to concordant negative results, TST-/QFT-GIT+ discordance was associated with foreign birth and age greater than or equal to 50 years, while TST+/QFT-GIT-discordance was associated with foreign birth, age 30-49 years, being Black and inversely associated with HIV. HIV infection was significantly associated with indeterminate QFT-GIT results. CONCLUSION: QFT-GIT may be an improvement over the TST for diagnosing LTBI in foreign-born and older persons, and may be as useful as the TST in HIV-infected persons. The sensitivity of both tests may be low in HIV-infected persons. JF - International Journal of Tuberculosis and Lung Disease AU - Weinfurter, P AU - Blumberg, H M AU - Goldbaum, G AU - Royce, R AU - Pang, J AU - Tapia, J AU - Bethel, J AU - Mazurek, G H AU - Toney, S AU - Albalak, R AD - Westat, 1650 Research Blvd, Rockville, MD 20850, USA, cwal@cdc.gov Y1 - 2011/08// PY - 2011 DA - Aug 2011 SP - 1056 EP - 1061 PB - International Union Against Tuberculosis and Lung Disease VL - 15 IS - 8 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology; Risk Abstracts; Health & Safety Science Abstracts KW - USA, North Carolina KW - Age KW - Mycobacterium KW - Infection KW - Drug abuse KW - substance abuse KW - Discordance KW - infection KW - Risk groups KW - Gold KW - Tuberculosis KW - Ethnic groups KW - Sex KW - Sensitivity KW - Data processing KW - Lung diseases KW - Skin tests KW - tuberculosis KW - Birth KW - Blood KW - Human immunodeficiency virus KW - homelessness KW - INE, USA, Washington, Seattle KW - USA, Georgia, Atlanta KW - Tuberculin KW - J 02400:Human Diseases KW - R2 23060:Medical and environmental health KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/893268447?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Predictors+of+discordant+tuberculin+skin+test+and+QuantiFERON+registered+-TB+Gold+In-Tube+results+in+various+high-risk+groups&rft.au=Weinfurter%2C+P%3BBlumberg%2C+H+M%3BGoldbaum%2C+G%3BRoyce%2C+R%3BPang%2C+J%3BTapia%2C+J%3BBethel%2C+J%3BMazurek%2C+G+H%3BToney%2C+S%3BAlbalak%2C+R&rft.aulast=Weinfurter&rft.aufirst=P&rft.date=2011-08-01&rft.volume=15&rft.issue=8&rft.spage=1056&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/10.5588%2Fijtld.10.0650 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-09-01 N1 - Last updated - 2013-12-16 N1 - SubjectsTermNotLitGenreText - Age; Data processing; Lung diseases; Drug abuse; Infection; Skin tests; Birth; Blood; Discordance; Gold; Risk groups; Tuberculosis; Tuberculin; Sex; substance abuse; tuberculosis; Sensitivity; Human immunodeficiency virus; infection; homelessness; Ethnic groups; Mycobacterium; USA, North Carolina; USA, Georgia, Atlanta; INE, USA, Washington, Seattle DO - http://dx.doi.org/10.5588/ijtld.10.0650 ER - TY - JOUR T1 - Ethical implications and practical considerations of ethnically targeted screening for genetic disorders: the case of hemoglobinopathy screening AN - 888116160; 15527831 AB - The prevalence of hemoglobinopathies differs among populations due to genetic differences and due to the protective effects of the heterozygote (carrier) state against malaria. Because of the difference in genetic distribution, public health programs have weighed the ethical versus practical implications of ethnically targeted versus universal newborn, and where applicable, prenatal screening. We examine newborn and prenatal screening for hemoglobinopathies in relation to the use of 'race' and ethnicity to assess risk for genetic conditions. First, categories of race/ethnicity are social constructs, therefore, observed or self-identified broad racial/ethnic categories are correlated but not necessarily reliable indicators of geographic ancestry or genetic risk. Second, targeting based on ethnicity poses serious issues of logistics and equity for public health programs and clinical services. In the past, newborn screening for hemoglobinopathies in the United States and United Kingdom was often selective, targeted to women of certain ethnic groups or areas with large concentrations of ethnic minority groups. Presently, newborn screening for hemoglobinopathies is universal in both countries and programs emphasize that individuals of all ethnic backgrounds are at risk for carrying a hemoglobin genetic variant. Reported race/ethnicity is still used as a criterion for offering prenatal carrier testing in the United States, where it is not a public health responsibility. In the United Kingdom, prenatal screening under the National Health Service is universal in high-prevalence areas and in low-prevalence areas is targeted based on reported ancestry. The continued use of targeted prenatal screening in both countries reflects the different purposes and modes of laboratory testing in newborn and prenatal screening. The ethical imperative to identify as many affected infants with life-threatening conditions as possible in newborn screening programs is not applicable to prenatal carrier testing. Because newborn screening dried blood spot specimens are tested for multiple disorders, targeted screening poses serious logistical challenges which is not the case in prenatal screening. JF - Ethnicity & Health AU - Hinton, Cynthia F AU - Grant, Althea M AU - Grosse, Scott D AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA, USA Y1 - 2011/08// PY - 2011 DA - Aug 2011 SP - 377 EP - 388 PB - Taylor & Francis Group Ltd., 2 Park Square Oxford OX14 4RN United Kingdom VL - 16 IS - 4-5 SN - 1355-7858, 1355-7858 KW - ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Risk Abstracts KW - hemoglobinopathies KW - newborn screening KW - prenatal carrier testing KW - ethics KW - ethnicity KW - Screening KW - Human diseases KW - Laboratory testing KW - Subpopulations KW - Malaria KW - Public health KW - Population genetics KW - USA KW - prenatal experience KW - Ethics KW - malaria KW - Ethnic groups KW - minority groups KW - Haemoglobins KW - Infants KW - responsibility KW - Q1 08484:Species interactions: parasites and diseases KW - R2 23060:Medical and environmental health KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/888116160?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ethnicity+%26+Health&rft.atitle=Ethical+implications+and+practical+considerations+of+ethnically+targeted+screening+for+genetic+disorders%3A+the+case+of+hemoglobinopathy+screening&rft.au=Hinton%2C+Cynthia+F%3BGrant%2C+Althea+M%3BGrosse%2C+Scott+D&rft.aulast=Hinton&rft.aufirst=Cynthia&rft.date=2011-08-01&rft.volume=16&rft.issue=4-5&rft.spage=377&rft.isbn=&rft.btitle=&rft.title=Ethnicity+%26+Health&rft.issn=13557858&rft_id=info:doi/10.1080%2F13557858.2010.541902 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-09-01 N1 - Last updated - 2015-10-28 N1 - SubjectsTermNotLitGenreText - Screening; Population genetics; Human diseases; Subpopulations; Malaria; Haemoglobins; Public health; prenatal experience; Laboratory testing; malaria; Ethics; minority groups; Ethnic groups; responsibility; Infants; USA DO - http://dx.doi.org/10.1080/13557858.2010.541902 ER - TY - JOUR T1 - Chlorine dioxide inactivation of bacterial threat agents AN - 888109177; 15452547 AB - Aims: To evaluate the efficacy of chlorine dioxide (ClO2) against seven species of bacterial threat (BT) agents in water. Methods and Results: Two strains of Bacillus anthracis spores, Yersinia pestis, Francisella tularensis, Burkholderia pseudomallei, Burkholderia mallei and Brucella species were each inoculated into a ClO2 solution with an initial concentration of 2.0 (spores only) and 0.25mgl-1 (all other bacteria) at pH 7 or 8, 5 or 25 degree C. At 0.25mgl-1 in potable water, six species were inactivated by at least three orders of magnitude within 10min. Bacillus anthracis spores required up to 7h at 5 degree C for the same inactivation with 2.0mgl-1 ClO2. Conclusions: Typical ClO2 doses used in water treatment facilities would be effective against all bacteria tested except B. anthracis spores that would require up to 7h with the largest allowable dose of 2mgl-1 ClO2. Other water treatment processes may be required in addition to ClO2 disinfection for effective spore removal or inactivation. Significance and Impact of Study: The data obtained from this study provide valuable information for water treatment facilities and public health officials in the event that a potable water supply is contaminated with these BT agents. JF - Letters in Applied Microbiology AU - Shams, A M AU - O'Connell, H AU - Arduino, MJ AU - Rose, L J AD - Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA Y1 - 2011/08// PY - 2011 DA - Aug 2011 SP - 225 EP - 230 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 53 IS - 2 SN - 0266-8254, 0266-8254 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology; Pollution Abstracts; Water Resources Abstracts; Aqualine Abstracts KW - Bacillus KW - inactivation KW - Bacillus anthracis KW - Spores KW - AQ 00001:Water Resources and Supplies KW - J:02400 KW - A:01380 KW - P 2000:FRESHWATER POLLUTION KW - SW 3060:Water treatment and distribution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/888109177?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Letters+in+Applied+Microbiology&rft.atitle=Chlorine+dioxide+inactivation+of+bacterial+threat+agents&rft.au=Shams%2C+A+M%3BO%27Connell%2C+H%3BArduino%2C+MJ%3BRose%2C+L+J&rft.aulast=Shams&rft.aufirst=A&rft.date=2011-08-01&rft.volume=53&rft.issue=2&rft.spage=225&rft.isbn=&rft.btitle=&rft.title=Letters+in+Applied+Microbiology&rft.issn=02668254&rft_id=info:doi/10.1111%2Fj.1472-765X.2011.03095.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-09-01 N1 - Document feature - figure 0 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Spores; inactivation; Bacillus anthracis DO - http://dx.doi.org/10.1111/j.1472-765X.2011.03095.x ER - TY - JOUR T1 - Racial and Ethnic Disparities in Hospitalizations and Deaths Associated with 2009 Pandemic Influenza A (H1N1) Virus Infections in the United States AN - 883030823; 15330848 AB - Using data from the Centers for Disease Control and Prevention's Behavioral Risk Factor Surveillance System, Emerging Infections Program Influenza-Associated Hospitalization Surveillance, and Influenza-Associated Pediatric Mortality Surveillance, we calculated race-ethnicity-specific, age-adjusted rates of self-reported influenza-like illness (ILI) and pH1N1-associated hospitalizations. We used [chi] super(2 tests to evaluate racial-ethnic disparities in ILI-associated health care-seeking behavior and pH1N1 hospitalization. To evaluate pediatric deaths, we compared racial-ethnic proportions of deaths against U.S. population distributions. Results: Prevalence of self-reported ILI was lower among Hispanics (6.5%), higher among American Indians/Alaska Natives (16.2%), and similar among non-Hispanic blacks (7.7%) compared with non-Hispanic whites (8.5%). No racial-ethnic differences were identified in ILI-associated health care-seeking behavior. Age-adjusted pH1N1-associated Emerging Infections Program hospitalization rates were higher among all minority populations (range: 8.1-10.9/100,000 population) compared with non-Hispanic whites (3.0/100,000). The proportion of pH1N1-associated pediatric deaths was higher than expected among Hispanics (31%) and lower than expected among non-Hispanic whites (45%) given the proportions of the U.S. population they comprise (22% and 58%, respectively). Conclusions: Racial-ethnic disparities in pH1N1-associated hospitalizations and pediatric deaths were identified. Vaccination remains the primary intervention for preventing influenza.) JF - Annals of Epidemiology AU - Dee, Deborah L AU - Bensyl, Diana M AU - Gindler, Jacqueline AU - Truman, Benedict I AU - Allen, Barbara G AU - D'Mello, Tiffany AU - Perez, Alejandro AU - Kamimoto, Laurie AU - Biggerstaff, Matthew AU - Blanton, Lenee AU - Fowlkes, Ashley AU - Glover, Maleeka J AU - Swerdlow, David L AU - Finelli, Lyn AD - Division of Reproductive Health, Centers for Disease Control and Prevention, ddee@cdc.gov ddee@cdc.gov ddee@cdc.gov ddee@cdc.gov ddee@cdc.gov Y1 - 2011/08// PY - 2011 DA - Aug 2011 SP - 623 EP - 630 PB - Elsevier B.V., Box 882 New York NY 10159 United States VL - 21 IS - 8 SN - 1047-2797, 1047-2797 KW - Virology & AIDS Abstracts; Risk Abstracts KW - Disease control KW - population distribution KW - disease control KW - Infection KW - influenza KW - pandemics KW - intervention KW - Risk factors KW - infection KW - prevention KW - Ethnic groups KW - USA, Alaska KW - Mortality KW - Data processing KW - Pediatrics KW - Vaccination KW - R2 23060:Medical and environmental health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/883030823?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annals+of+Epidemiology&rft.atitle=Racial+and+Ethnic+Disparities+in+Hospitalizations+and+Deaths+Associated+with+2009+Pandemic+Influenza+A+%28H1N1%29+Virus+Infections+in+the+United+States&rft.au=Dee%2C+Deborah+L%3BBensyl%2C+Diana+M%3BGindler%2C+Jacqueline%3BTruman%2C+Benedict+I%3BAllen%2C+Barbara+G%3BD%27Mello%2C+Tiffany%3BPerez%2C+Alejandro%3BKamimoto%2C+Laurie%3BBiggerstaff%2C+Matthew%3BBlanton%2C+Lenee%3BFowlkes%2C+Ashley%3BGlover%2C+Maleeka+J%3BSwerdlow%2C+David+L%3BFinelli%2C+Lyn&rft.aulast=Dee&rft.aufirst=Deborah&rft.date=2011-08-01&rft.volume=21&rft.issue=8&rft.spage=623&rft.isbn=&rft.btitle=&rft.title=Annals+of+Epidemiology&rft.issn=10472797&rft_id=info:doi/10.1016%2Fj.annepidem.2011.03.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-08-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Mortality; pandemics; Data processing; Pediatrics; Risk factors; Disease control; Infection; Vaccination; intervention; prevention; infection; population distribution; disease control; Ethnic groups; influenza; USA, Alaska DO - http://dx.doi.org/10.1016/j.annepidem.2011.03.002 ER - TY - JOUR T1 - The connection between human papillomavirus and oropharyngeal squamous cell carcinomas in the United States: implications for dentistry. AN - 880715079; 21804058 AB - Results from studies conducted in the past several years suggest that some oropharyngeal cancers, those of the base of the tongue and the tonsils, are associated with high-risk types of human papillomavirus (HPV). In this article, the authors summarize the available evidence regarding the epidemiology of HPV-associated oropharyngeal cancers in the United States, the available HPV vaccines and the implications of these for dentistry. They also examine the differences in HPV prevalence between cancers of the oral cavity and those of the oropharynx. The authors searched PubMed, Web of Science, The Cochrane Library and the National Guideline Clearinghouse to identify English-language systematic reviews and meta-analyses focused on HPV-associated oropharyngeal squamous cell cancers published from January 2005 through May 2011. Molecular and epidemiologic evidence suggest a strong etiologic association of HPV with oropharyngeal cancers. The incidence of oropharyngeal cancers in the United States has increased between 1973 and 2007, whereas that of cancers at other head and neck sites has decreased steadily. Compared with HPV-negative cancers, HPV-positive oropharyngeal cancers are associated with certain sexual behaviors, occur more often among white men and people who do not use tobacco or alcohol, and may occur in a population younger by about four years (median ages, 52-56 years). Despite often having a later stage of diagnosis, people with HPV-positive oropharyngeal cancers have a lower risk of dying or recurrence than do those with HPV-negative cancers. The effectiveness of the HPV vaccine in preventing oropharyngeal cancers is unknown. Dental health care personnel (DHCP) should be knowledgeable about the role of HPV in carcinogenesis, the association of HPV with oropharyngeal cancers and HPV vaccines, and they should be prompt in referring patients with suggestive symptoms for evaluation. DHCP can play an important role in increasing patients' knowledge about HPV and oropharyngeal cancers. Copyright © 2011 American Dental Association. All rights reserved. JF - Journal of the American Dental Association (1939) AU - Cleveland, Jennifer L AU - Junger, Michele L AU - Saraiya, Mona AU - Markowitz, Lauri E AU - Dunne, Eileen F AU - Epstein, Joel B AD - Division of Oral Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, MS F-10, 4770 Buford Highway, Atlanta, Ga. 30341, USA. JLCleveland@cdc.gov Y1 - 2011/08// PY - 2011 DA - August 2011 SP - 915 EP - 924 VL - 142 IS - 8 KW - Papillomavirus Vaccines KW - 0 KW - Dentistry KW - Index Medicus KW - Sexual Behavior KW - Neoplasm Recurrence, Local -- epidemiology KW - Age Factors KW - Risk Factors KW - Humans KW - Mouth Neoplasms -- virology KW - Incidence KW - United States -- epidemiology KW - Mouth Neoplasms -- epidemiology KW - Papillomavirus Infections -- epidemiology KW - Oropharyngeal Neoplasms -- virology KW - Carcinoma, Squamous Cell -- epidemiology KW - Oropharyngeal Neoplasms -- epidemiology KW - Alphapapillomavirus -- physiology KW - Carcinoma, Squamous Cell -- virology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/880715079?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+American+Dental+Association+%281939%29&rft.atitle=The+connection+between+human+papillomavirus+and+oropharyngeal+squamous+cell+carcinomas+in+the+United+States%3A+implications+for+dentistry.&rft.au=Cleveland%2C+Jennifer+L%3BJunger%2C+Michele+L%3BSaraiya%2C+Mona%3BMarkowitz%2C+Lauri+E%3BDunne%2C+Eileen+F%3BEpstein%2C+Joel+B&rft.aulast=Cleveland&rft.aufirst=Jennifer&rft.date=2011-08-01&rft.volume=142&rft.issue=8&rft.spage=915&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+American+Dental+Association+%281939%29&rft.issn=1943-4723&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-12-07 N1 - Date created - 2011-08-01 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Comment In: J Am Dent Assoc. 2012 May;143(5):440 [22547710] J Am Dent Assoc. 2011 Nov;142(11):1237-8 [22041408] Erratum In: J Am Dent Assoc. 2011 Sep;142(9):1005-6 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Sexual mixing patterns among social networks of HIV-positive and HIV-negative Beijing men who have sex with men: a multilevel comparison using roundtable network mapping AN - 880335959; 4218615 AB - Men who have sex with men (MSM) are of immediate concern in China's HIV epidemic. In 2008, approximately 2.5-6.5% of China's eight million MSM were HIV positive, while MSM represented 11% of all new HIV cases. Two factors that will in-part determine HIV-transmission dynamics among MSM, are sexual mixing patterns and the social networks which shape them. Sexual mixing patterns and social networks of Chinese MSM, however, remain poorly understood with little refined data available. One reason is that stigma discourages disclosure of names and identifiers to researchers. Using an alternative network-mapping approach, matched case-control design, and snowball sampling, this pilot study sought to compare characteristics of social networks of HIV-positive and HIV-negative Beijing MSM at the individual, dyad, and network levels. First, HIV-negative MSM controls were matched to HIV-positive MSM cases based on age, education, residency, and ethnicity. Then, each case or control and their MSM social network convened at a specific time and location with study investigators. Venues included health clinics, karaoke clubs, brothels, and community centers. Then, using arbitrarily assigned numbers in lieu of actual names, all participants simultaneously completed self-administered surveys regarding their sexual relationships with other participants of the same social network. These new findings indicate that cross-generational sex (anal or oral sex between men with >/=10 years age difference) was more prevalent among social networks of HIV-positive MSM, and was due to older age structure of the social network, rather than behavioral differences in sex-partner selection. Members of social networks of HIV-positive MSM were also less likely to have ever disclosed their MSM identity to non-MSM. Future studies should partner with MSM advocacy groups to explore behavioral and structural interventions as possible means of reducing the cross-generational sex and sexual identity-development issues elevating HIV risk for young Chinese MSM. Reprinted by permission of Routledge, Taylor & Francis Ltd. JF - AIDS care AU - Ruan, Yuhua AU - Pan, Stephen AU - Chamot, Eric AU - Qian, Han-zhu AU - Li, Dongliang AU - Li, Qing-chun AU - Liang, Hong-yuan AU - Spittal, Patricia AU - Shao, Yiming AU - Kristensen, Sibylle AD - Chinese Center for Disease Control and Prevention ; University of Alabama, Birmingham ; University of British Columbia Y1 - 2011/08// PY - 2011 DA - Aug 2011 SP - 1014 EP - 1025 VL - 23 IS - 8 SN - 0954-0121, 0954-0121 KW - Sociology KW - Risk KW - Social networks KW - Sexual behaviour KW - Interpersonal relations KW - Diseases KW - HIV KW - China KW - Homosexuals KW - Public health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/880335959?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+care&rft.atitle=Sexual+mixing+patterns+among+social+networks+of+HIV-positive+and+HIV-negative+Beijing+men+who+have+sex+with+men%3A+a+multilevel+comparison+using+roundtable+network+mapping&rft.au=Ruan%2C+Yuhua%3BPan%2C+Stephen%3BChamot%2C+Eric%3BQian%2C+Han-zhu%3BLi%2C+Dongliang%3BLi%2C+Qing-chun%3BLiang%2C+Hong-yuan%3BSpittal%2C+Patricia%3BShao%2C+Yiming%3BKristensen%2C+Sibylle&rft.aulast=Ruan&rft.aufirst=Yuhua&rft.date=2011-08-01&rft.volume=23&rft.issue=8&rft.spage=1014&rft.isbn=&rft.btitle=&rft.title=AIDS+care&rft.issn=09540121&rft_id=info:doi/10.1080%2F09540121.2010.542127 LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 5703 3617 6220; 11873 8634; 11563 1025 1542 11325 6071; 11035; 10449 5772; 3617 6220; 5971; 6823; 93 116 30 DO - http://dx.doi.org/10.1080/09540121.2010.542127 ER - TY - JOUR T1 - Effectiveness of home-based, multi-trigger, multicomponent interventions with an environmental focus for reducing asthma morbidity: a community guide systematic review. AN - 879484314; 21767736 AB - Asthma exacerbations are commonly triggered by exposure to allergens and irritants within the home. The purpose of this review was to evaluate evidence that interventions that target reducing these triggers through home visits may be beneficial in improving asthma outcomes. The interventions involve home visits by trained personnel to conduct two or more components that address asthma triggers in the home. Intervention components focus on reducing exposures to a range of asthma triggers (allergens and irritants) through environmental assessment, education, and remediation. Using methods previously developed for the Guide to Community Preventive Services, a systematic review was conducted to evaluate the evidence on effectiveness of home-based, multi-trigger, multicomponent interventions with an environmental focus to improve asthma-related morbidity outcomes. The literature search identified over 10,800 citations. Of these, 23 studies met intervention and quality criteria for inclusion in the final analysis. In the 20 studies targeting children and adolescents, the number of days with asthma symptoms (symptom-days) was reduced by 0.8 days per 2 weeks, which is equivalent to 21.0 symptom-days per year (range of values: reduction of 0.6 to 2.3 days per year); school days missed were reduced by 12.3 days per year (range of values: reduction of 3.4 to 31.2 days per year); and the number of asthma acute care visits were reduced by 0.57 visits per year (interquartile interval: reduction of 0.33 to 1.71 visits per year). Only three studies reported outcomes among adults with asthma, finding inconsistent results. Home-based, multi-trigger, multicomponent interventions with an environmental focus are effective in improving overall quality of life and productivity in children and adolescents with asthma. The effectiveness of these interventions in adults is inconclusive due to the small number of studies and inconsistent results. Additional studies are needed to (1) evaluate the effectiveness of these interventions in adults and (2) determine the individual contributions of the various intervention components. Published by Elsevier Inc. JF - American journal of preventive medicine AU - Crocker, Deidre D AU - Kinyota, Stella AU - Dumitru, Gema G AU - Ligon, Colin B AU - Herman, Elizabeth J AU - Ferdinands, Jill M AU - Hopkins, David P AU - Lawrence, Briana M AU - Sipe, Theresa A AU - Task Force on Community Preventive Services AD - Air Pollution and Respiratory Health Branch, Division of Environmental Hazards and Health Effects, National Center for Environmental Health, National Center for Immunization and Respiratory Diseases, CDC, Atlanta, Georgia 30333, USA. ; Task Force on Community Preventive Services Y1 - 2011/08// PY - 2011 DA - August 2011 SP - S5 EP - 32 VL - 41 IS - 2 Suppl 1 KW - Allergens KW - 0 KW - Index Medicus KW - House Calls KW - Environmental Restoration and Remediation -- methods KW - Efficiency KW - Housing KW - Humans KW - Adult KW - Quality of Life KW - Child KW - Allergens -- adverse effects KW - Adolescent KW - Asthma -- epidemiology KW - Asthma -- etiology KW - Asthma -- prevention & control KW - Home Care Services -- organization & administration KW - Environmental Exposure -- prevention & control KW - Environmental Exposure -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/879484314?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+journal+of+preventive+medicine&rft.atitle=Effectiveness+of+home-based%2C+multi-trigger%2C+multicomponent+interventions+with+an+environmental+focus+for+reducing+asthma+morbidity%3A+a+community+guide+systematic+review.&rft.au=Crocker%2C+Deidre+D%3BKinyota%2C+Stella%3BDumitru%2C+Gema+G%3BLigon%2C+Colin+B%3BHerman%2C+Elizabeth+J%3BFerdinands%2C+Jill+M%3BHopkins%2C+David+P%3BLawrence%2C+Briana+M%3BSipe%2C+Theresa+A%3BTask+Force+on+Community+Preventive+Services&rft.aulast=Crocker&rft.aufirst=Deidre&rft.date=2011-08-01&rft.volume=41&rft.issue=2+Suppl+1&rft.spage=S5&rft.isbn=&rft.btitle=&rft.title=American+journal+of+preventive+medicine&rft.issn=1873-2607&rft_id=info:doi/10.1016%2Fj.amepre.2011.05.012 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-11-21 N1 - Date created - 2011-07-19 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Comment In: Am J Prev Med. 2011 Aug;41(2 Suppl 1):S57-8 [21767739] Am J Prev Med. 2011 Aug;41(2 Suppl 1):S55-6 [21767738] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.amepre.2011.05.012 ER - TY - JOUR T1 - Israeli Adolescents Exposed to Community and Terror Violence: The Protective Role of Social Support AN - 876244779; 14993613 AB - This study investigates how social support may protect Israeli early adolescents who have witnessed community violence from engaging in violent behavior when they have also witnessed terror violence. The study examines how support from parents, school, and friends could serve as protective, despite the interactive risk effects of witnessing community and terror violence. In general, results indicate that support from parents operated as a protective factor, whereas support from friends acted as a risk by increasing the likelihood of violent behavior. Support from school has both a protective and risk effect, depending on the type of violence exposure witnessed. The extent to which these facets of social support operated as risk or protective factors is conditional on whether youth had also witnessed terror violence, and terror violence appear to moderate each of the three facets of support differently. The implications of these findings and intervention initiatives for Israeli youth are discussed. JF - Journal of Early Adolescence AU - Brookmeyer, Kathryn A AU - Henrich, Christopher C AU - Cohen, Guina AU - Shahar, Golan AD - Centers for Disease Control and Prevention, KBrookmeyer@cdc.gov Y1 - 2011/08// PY - 2011 DA - Aug 2011 SP - 577 EP - 603 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU UK VL - 31 IS - 4 SN - 0272-4316, 0272-4316 KW - Risk Abstracts KW - schools KW - intervention KW - Violence KW - Adolescents KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/876244779?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Early+Adolescence&rft.atitle=Israeli+Adolescents+Exposed+to+Community+and+Terror+Violence%3A+The+Protective+Role+of+Social+Support&rft.au=Brookmeyer%2C+Kathryn+A%3BHenrich%2C+Christopher+C%3BCohen%2C+Guina%3BShahar%2C+Golan&rft.aulast=Brookmeyer&rft.aufirst=Kathryn&rft.date=2011-08-01&rft.volume=31&rft.issue=4&rft.spage=577&rft.isbn=&rft.btitle=&rft.title=Journal+of+Early+Adolescence&rft.issn=02724316&rft_id=info:doi/10.1177%2F0272431610366247 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-07-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - schools; intervention; Violence; Adolescents DO - http://dx.doi.org/10.1177/0272431610366247 ER - TY - JOUR T1 - Trends in Tuberculosis in Taiwan, 2002-2008 AN - 1773823778; 15458649 JF - Journal of the Formosan Medical Association AU - Lo, Hsiu-Yun AU - Chou, Pesus AU - Yang, Shiang-Lin AU - Lee, Cheng-Yi AU - Kuo, Hsu-Sung Y1 - 2011/08// PY - 2011 DA - August 2011 SP - 501 EP - 510 PB - Excerpta Medica Asia Ltd., 19/F, Eight Commercial Tower Chai Wan Hong Kong China VL - 110 IS - 8 SN - 0929-6646, 0929-6646 KW - Microbiology Abstracts B: Bacteriology KW - incidence KW - mortality KW - Taiwan KW - tuberculosis KW - Mycobacterium KW - Tuberculosis KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1773823778?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+Formosan+Medical+Association&rft.atitle=Trends+in+Tuberculosis+in+Taiwan%2C+2002-2008&rft.au=Lo%2C+Hsiu-Yun%3BChou%2C+Pesus%3BYang%2C+Shiang-Lin%3BLee%2C+Cheng-Yi%3BKuo%2C+Hsu-Sung&rft.aulast=Lo&rft.aufirst=Hsiu-Yun&rft.date=2011-08-01&rft.volume=110&rft.issue=8&rft.spage=501&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+Formosan+Medical+Association&rft.issn=09296646&rft_id=info:doi/10.1016%2FS0929-6646%2811%2960076-4 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2016-03-01 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Tuberculosis; Mycobacterium DO - http://dx.doi.org/10.1016/S0929-6646(11)60076-4 ER - TY - JOUR T1 - Factors Associated with Low Drinking Water Intake among Adolescents: The Florida Youth Physical Activity and Nutrition Survey, 2007 AN - 1022563921; 15592699 AB - There is limited information on which characteristics are associated with water intake among adolescents. This cross-sectional study examined the association between demographic, dietary, and behavioral factors and low water intake as the outcome measure. Analyses were based on the 2007 Florida Youth Physical Activity and Nutrition Survey using a representative sample of 4,292 students in grades six through eight in 86 Florida public middle schools. Multivariable logistic regression was used to calculate adjusted odds ratios (ORs) and 95% confidence intervals for factors associated with low water intake (3 glasses water per day). About 64% of students had low water intake. Factors significantly associated with low water intake were Hispanic ethnicity and non-Hispanic other (vs non-Hispanic white; ORs 0.79 and 0.76, respectively), drinking no 100% juice, drinking it 1 time/day, and drinking it 1 to 2 times/day (vs drinking it =3 times/day; ORs 1.83, 1.91, and 1.32, respectively), drinking no milk and drinking 2 glasses of milk/day (vs drinking =2 glasses/day; ORs 1.42 and 1.41, respectively), drinking 1 soda/day (vs drinking none; OR 1.40), drinking fruit-flavored drinks/sports drinks 1 time/day and drinking it =1 time/day (vs drinking none; ORs 1.49 and 1.41, respectively), eating at a fast-food restaurant =3 days/week (vs none; OR 1.38, respectively), not participating on team sports or participating on 1 to 2 team sports in previous 12 months (vs participating on =3 teams; ORs 1.77 and 1.24, respectively), and consuming snack/soda while watching television/movies "sometimes" and "most/every time" (vs never; ORs 1.65 and 2.20, respectively). The strongest factor associated with low water intake was frequent consumption of snacks/sodas while watching television/movies. Although study findings should be corroborated in other states and in a nationally representative sample, they may be useful in targeting adolescents for increased water consumption. JF - Journal of the American Dietetic Association AU - Park, Sohyun AU - Sherry, Bettylou AU - O'Toole, Terrence AU - Huang, Youjie Y1 - 2011/08// PY - 2011 DA - Aug 2011 SP - 1211 EP - 1217 PB - Elsevier B.V., Box 882 New York NY 10159 United States VL - 111 IS - 8 SN - 0002-8223, 0002-8223 KW - Physical Education Index KW - Adolescence KW - Exercise KW - Nutrition KW - Students KW - Surveys KW - Team sports KW - Television KW - Water KW - Youth KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1022563921?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+American+Dietetic+Association&rft.atitle=Factors+Associated+with+Low+Drinking+Water+Intake+among+Adolescents%3A+The+Florida+Youth+Physical+Activity+and+Nutrition+Survey%2C+2007&rft.au=Park%2C+Sohyun%3BSherry%2C+Bettylou%3BO%27Toole%2C+Terrence%3BHuang%2C+Youjie&rft.aulast=Park&rft.aufirst=Sohyun&rft.date=2011-08-01&rft.volume=111&rft.issue=8&rft.spage=1211&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+American+Dietetic+Association&rft.issn=00028223&rft_id=info:doi/10.1016%2Fj.jada.2011.05.006 LA - English DB - Physical Education Index N1 - Date revised - 2012-06-01 N1 - Last updated - 2012-08-10 N1 - SubjectsTermNotLitGenreText - Adolescence; Television; Team sports; Surveys; Exercise; Students; Nutrition; Youth; Water DO - http://dx.doi.org/10.1016/j.jada.2011.05.006 ER - TY - JOUR T1 - Multi-City Assessment of Lifetime Pregnancy Involvement among Street Youth, Ukraine AN - 1008827393; 16469871 AB - Although street youth are at increased risk of lifetime pregnancy involvement (LPI), or ever becoming or getting someone pregnant, no reports to date describe the epidemiology of LPI among systematically sampled street youth from multiple cities outside of North America. The purpose of our assessment was to describe the prevalence of and risk factors associated with LPI among street youth from three Ukrainian cities. We used modified time-location sampling to conduct a cross-sectional assessment in Odesa, Kyiv, and Donetsk that included citywide mapping of 91 public venue locations frequented by street youth, random selection of 74 sites, and interviewing all eligible and consenting street youth aged 15-24 years found at sampled sites (n=929). Characteristics of youth and prevalence of LPI overall and by demographic, social, sexual, and substance use risk factors, were estimated separately for males and females. Adjusted odds ratios (AORs) were calculated with multivariable logistic regression and effect modification by gender was examined. Most (96.6%) eligible youth consented to participate. LPI was reported for 41.7% of females (93/223) and 23.5% of males (166/706). For females, LPI was significantly elevated and highest (>70%) among those initiating sexual activity at less than or equal to 12 years and for those reporting lifetime anal sex and exchanging sex for goods. For males, LPI was significantly elevated and highest (>40%) among those who reported lifetime anal sex and history of a sexually transmitted infection. Overall, risk factors associated with LPI were similar for females and males. Among the total sample (females and males combined), significant independent risk factors with AORs greater than or equal to 2.5 included female gender, being aged 20-24 years, having five to six total adverse childhood experiences, initiating sex at age less than or equal to 12 or 13-14 years, lifetime anal sex, most recent sex act unprotected, and lifetime exchange of sex for goods. Among street youth with LPI (n=259), the most recent LPI event was reported to be unintended by 63.3% and to have ended in abortion by 43.2%. In conclusion, our assessment documented high rates of LPI among Ukrainian street youth who, given the potential for negative outcomes and the challenges of raising a child on the streets, are in need of community-based pregnancy prevention programs and services. Promising preventive strategies are discussed, which are likely applicable to other urban populations of street-based youth as well. JF - Journal of Urban Health AU - Zapata, Lauren B AU - Kissin, Dmitry M AU - Robbins, Cheryl L AU - Finnerty, Erin AU - Skipalska, Halyna AU - Yorick, Roman V AU - Jamieson, Denise J AU - Marchbanks, Polly A AU - Hillis, Susan D AD - Division of Reproductive Health, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Atlanta, GA, USA, lzapata@cdc.gov Y1 - 2011/08// PY - 2011 DA - Aug 2011 SP - 779 EP - 792 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 88 IS - 4 SN - 1099-3460, 1099-3460 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Gender KW - Pregnancy KW - Risk factors KW - Urban areas KW - anal sex KW - community involvement KW - infectious diseases KW - sexually transmitted diseases KW - urban populations KW - North America KW - Ukraine KW - R2 23060:Medical and environmental health KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1008827393?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Urban+Health&rft.atitle=Multi-City+Assessment+of+Lifetime+Pregnancy+Involvement+among+Street+Youth%2C+Ukraine&rft.au=Zapata%2C+Lauren+B%3BKissin%2C+Dmitry+M%3BRobbins%2C+Cheryl+L%3BFinnerty%2C+Erin%3BSkipalska%2C+Halyna%3BYorick%2C+Roman+V%3BJamieson%2C+Denise+J%3BMarchbanks%2C+Polly+A%3BHillis%2C+Susan+D&rft.aulast=Zapata&rft.aufirst=Lauren&rft.date=2011-08-01&rft.volume=88&rft.issue=4&rft.spage=779&rft.isbn=&rft.btitle=&rft.title=Journal+of+Urban+Health&rft.issn=10993460&rft_id=info:doi/10.1007%2Fs11524-011-9596-z LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-01 N1 - Last updated - 2012-05-18 N1 - SubjectsTermNotLitGenreText - infectious diseases; anal sex; Risk factors; Gender; urban populations; community involvement; sexually transmitted diseases; Urban areas; Pregnancy; North America; Ukraine DO - http://dx.doi.org/10.1007/s11524-011-9596-z ER - TY - JOUR T1 - The reduction of selenite by bacillus licheniformis AN - 1366835364; 675794-1 AB - Bacillus Licheniformi, which can reduce the toxic selenite anion to red elemental selenium(Se (super 0) ), was isolated from a carbonaceous mudstone with high content of Se. The results showed that this strain can stand in 320 mM SeO (super 2-) (sub 3) and in more than 1000 mM SeO (super 2-) (sub 4) . However, the high concentration of SeO (super 2-) (sub 3) can inhibit the growth of the strain in liquid medium(YEG). No matter in aerobic culture or anaerobic culture that the strain was inoculated, it can reduce selenite anion to nanospheric elemental selenium granules, distributed around or within the cells. In the liquid YEG medium contains 5mM of selenite, the transformed efficiency of Se (super 4+) to Se (super 0) by Bacillus licheniformi was 42% approximately. Since no rigorous requirement for Bacillus licheniformi to live, it is suitable to be selected in microbial remediation techniques as the strains that cope with selenium pollutions, and to produce the nano-Se granules with bioavailability. At the same time, the phenomena of selenite anions reduced to elemental Se by the bacterial provides a chance to further understand the microbial mineralization of selenium in the environment. JF - Kuangwu Yanshi Diqiuhuaxue Tongbao = Bulletin of Mineralogy, Petrology and Geochemistry AU - Zhu, Jianming AU - Lei, Lei AU - Xiao, Xiang AU - Yuan, Yongqiang AU - Qin, Haibo AU - Su, Hui Y1 - 2011/07/10/ PY - 2011 DA - 2011 Jul 10 SP - 245 EP - 250 PB - Zhongguo Kuangwu Yanshi Diqiu Huaxue Xuehui, Guiyang VL - 30 IS - 3 SN - 1007-2802, 1007-2802 KW - biomineralization KW - experimental studies KW - sulfates KW - selenium KW - lichens KW - biochemistry KW - selenite KW - chemical reactions KW - Bacillus licheniformis KW - bacteria KW - reduction KW - geochemistry KW - Bacillus KW - 02A:General geochemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1366835364?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefinprocess&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Kuangwu+Yanshi+Diqiuhuaxue+Tongbao+%3D+Bulletin+of+Mineralogy%2C+Petrology+and+Geochemistry&rft.atitle=The+reduction+of+selenite+by+bacillus+licheniformis&rft.au=Zhu%2C+Jianming%3BLei%2C+Lei%3BXiao%2C+Xiang%3BYuan%2C+Yongqiang%3BQin%2C+Haibo%3BSu%2C+Hui&rft.aulast=Zhu&rft.aufirst=Jianming&rft.date=2011-07-10&rft.volume=30&rft.issue=3&rft.spage=245&rft.isbn=&rft.btitle=&rft.title=Kuangwu+Yanshi+Diqiuhuaxue+Tongbao+%3D+Bulletin+of+Mineralogy%2C+Petrology+and+Geochemistry&rft.issn=10072802&rft_id=info:doi/ L2 - http://www.ceps.com.tw/ec/ecJnlIntro.aspx?Jnliid=1270 LA - Chinese DB - GeoRef N1 - Copyright - GeoRef in Process, Copyright 2017, American Geosciences Institute. After editing and indexing, this record will be added to Georef. N1 - Number of references - 18 N1 - Document feature - illus. N1 - Last updated - 2017-01-24 N1 - SubjectsTermNotLitGenreText - Bacillus; Bacillus licheniformis; bacteria; biochemistry; biomineralization; chemical reactions; experimental studies; geochemistry; lichens; reduction; selenite; selenium; sulfates ER - TY - JOUR T1 - Vaccination Coverage Among U.S. Adolescents Aged 13-17 Years Eligible for the Vaccines for Children Program, 2009 AN - 925720437; 2011-170040 AB - Objectives. We compared (1) characteristics of adolescents who are and are not entitled to receive free vaccines from the Vaccines for Children (VFC) program and (2) vaccination coverage with meningococcal conjugate (MCV4), quadrivalent human papillomavirus (HPV4), and tetanus-diphtheria-acellular pertussis (Tdap) vaccines among VFC-eligible and non-VFC-eligible adolescents. Methods. We analyzed data from the 2009 National Immunization Survey-Teen, a nationally representative, random-digit-dialed survey of households with adolescents aged 13-17 years (n=20,066). Differences in sociodemographic characteristics and provider-reported vaccination coverage were evaluated using t-tests. Results. Overall, 32.1% (+/- 1.2%) of adolescents were VFC-eligible. VFC-eligible adolescents were significantly less likely than non-VFC-eligible adolescents to be white and to live in suburban areas, and more likely to live in poverty and to have younger and less educated mothers. Nationally, coverage among non-VFC-eligible adolescents was 57.1% (+/- 1.5%) for 1+ dose of Tdap, 55.4% (+/- 1.5%) for 1+ dose of MCV4, and 43.2% (+/- 2.2%) for 1+ dose of HPV4. Coverage among VFC-eligible adolescents was 52.5% (+/- 2.4%) for 1+ dose Tdap, 50.1% (+/- 2.4%) for 1+ dose of MCV4, and 46.6% (+/- 3.5%) for 1+ dose of HPV4. Only 27.5% (+/- 1.8%) of non-VFC-eligible adolescents and 25.0% (+/- 2.9%) of VFC-eligible adolescents received 3+ doses of HPV4. Vaccination coverage was significantly higher among non-VFC-eligible adolescents for Tdap and MCV4, but not for one-dose or three-dose HPV4. Conclusions. Coverage with some recommended vaccines is lower among VFC-eligible adolescents compared with non-VFC-eligible adolescents. Continued monitoring of adolescent vaccination rates, particularly among VFC-eligible populations, is needed to ensure that all adolescents receive all routinely recommended vaccines. Adapted from the source document. JF - Public Health Reports AU - Lindley, Megan C AU - Smith, Philip J AU - Rodewald, Lance E AD - Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases, 1600 Clifton Rd. NE, MS E-52, Atlanta, GA 30333; tel. 404-639-8717; fax 404-639-8614 Y1 - 2011/07// PY - 2011 DA - July 2011 SP - 124 EP - 134 PB - Association of Schools of Public Health, Washington DC VL - 126 IS - Supplement 2 SN - 0033-3549, 0033-3549 KW - Health conditions and policy - Medicine and health care KW - Population groups, population policy, and demographics - Children and youth KW - Population groups, population policy, and demographics - National, ethnic, and minority groups KW - Health conditions and policy - Diseases and disorders KW - Population groups, population policy, and demographics - Demography and census KW - Population groups, population policy, and demographics - Women KW - Social conditions and policy - Marriage and family life KW - Education and education policy - Statistics, research, research methods, and research support KW - Social conditions and policy - Social conditions and problems KW - Economic conditions and policy - Economic conditions KW - Whites KW - Poverty KW - Mothers KW - Households KW - Cervical cancer KW - Surveys KW - Population KW - Children KW - Vaccination and vaccines KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/925720437?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Public+Health+Reports&rft.atitle=Vaccination+Coverage+Among+U.S.+Adolescents+Aged+13-17+Years+Eligible+for+the+Vaccines+for+Children+Program%2C+2009&rft.au=Lindley%2C+Megan+C%3BSmith%2C+Philip+J%3BRodewald%2C+Lance+E&rft.aulast=Lindley&rft.aufirst=Megan&rft.date=2011-07-01&rft.volume=126&rft.issue=Supplement+2&rft.spage=124&rft.isbn=&rft.btitle=&rft.title=Public+Health+Reports&rft.issn=00333549&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2012-03-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Vaccination and vaccines; Children; Whites; Cervical cancer; Households; Mothers; Population; Surveys; Poverty ER - TY - JOUR T1 - Vaccination Coverage Among U.S. Children Aged 19-35 Months Entitled by the Vaccines for Children Program, 2009 AN - 925720435; 2011-170039 AB - Objectives. Following the measles outbreaks of the late 1980s and early 1990s, vaccination coverage was found to be low nationally, and there were pockets of underimmunized children primarily in inner cities. We described the percentage and demographics of children who were entitled to the Vaccines for Children (VFC) program in 2009 and evaluated whether Healthy People 2010 (HP 2010) vaccination coverage objectives of 90% were achieved among these children. Methods. We analyzed data from 16,967 children aged 19-35 months sampled by the National Immunization Survey in 2009. VFC-entitled children included children who were (1) on Medicaid, (2) not covered by health insurance, (3) of American Indian/Alaska Native race/ethnicity, or (4) covered by private health insurance that did not pay all of the costs of vaccines, but who were vaccinated at a Federally Qualified Health Center or a Rural Health Center. Results. An estimated 49.7% of all children aged 19-35 months were entitled to VFC vaccines. Compared with children who did not qualify for VFC, the VFC-entitled children were significantly more likely to be Hispanic or non-Hispanic black; to have a mother who was widowed, divorced, separated, or never married; and to live in a household with an annual income below the federal poverty level. Mothers of VFC-entitled children were significantly less likely to have some college experience or to be college graduates. Of nine vaccines analyzed, two vaccines -- polio at 91.7% and hepatitis B at 92.2% -- achieved the HP 2010 90% coverage objective for VFC-entitled children, and four others, including measles-mumps-rubella at 88.8%, achieved greater than 80% coverage. Conclusions. Today, children with demographic characteristics like those of children who were at the epicenter of the measles outbreaks two decades ago are entitled to VFC vaccines at no cost, and have achieved high vaccination coverage levels. Adapted from the source document. JF - Public Health Reports AU - Smith, Philip J AU - Lindley, Megan C AU - Rodewald, Lance E AD - Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases, 1600 Clifton Rd. NE, MS E-62, Atlanta, GA 30333; tel. 404-639-8729; fax 404-639-3266 Y1 - 2011/07// PY - 2011 DA - July 2011 SP - 109 EP - 123 PB - Association of Schools of Public Health, Washington DC VL - 126 IS - Supplement 2 SN - 0033-3549, 0033-3549 KW - Population groups, population policy, and demographics - Children and youth KW - Health conditions and policy - Medicine and health care KW - Health conditions and policy - Diseases and disorders KW - Economic conditions and policy - Economic theory KW - Business and service sector - Insurance KW - Health conditions and policy - Health and health policy KW - Population groups, population policy, and demographics - Women KW - Social conditions and policy - Marriage and family life KW - Population groups, population policy, and demographics - National, ethnic, and minority groups KW - Population groups, population policy, and demographics - Demography and census KW - Education and education policy - Education personnel and population KW - Social conditions and policy - Public welfare and social services KW - Education and education policy - Statistics, research, research methods, and research support KW - Population groups, population policy, and demographics - Native races KW - Business and service sector - Accounting KW - Social conditions and poli KW - Indians KW - Inner cities KW - Medicaid program KW - Blacks KW - Measles KW - Mothers KW - Surveys KW - Health insurance KW - Children KW - Hispanics KW - Demographics KW - Income KW - Hepatitis KW - Cost KW - Poverty KW - Households KW - College graduates KW - Native races KW - Alaska KW - Vaccination and vaccines KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/925720435?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Public+Health+Reports&rft.atitle=Vaccination+Coverage+Among+U.S.+Children+Aged+19-35+Months+Entitled+by+the+Vaccines+for+Children+Program%2C+2009&rft.au=Smith%2C+Philip+J%3BLindley%2C+Megan+C%3BRodewald%2C+Lance+E&rft.aulast=Smith&rft.aufirst=Philip&rft.date=2011-07-01&rft.volume=126&rft.issue=Supplement+2&rft.spage=109&rft.isbn=&rft.btitle=&rft.title=Public+Health+Reports&rft.issn=00333549&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2012-03-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Children; Vaccination and vaccines; Measles; Cost; Health insurance; Demographics; Mothers; Blacks; Households; College graduates; Medicaid program; Alaska; Hepatitis; Hispanics; Surveys; Native races; Income; Poverty; Indians; Inner cities ER - TY - JOUR T1 - Analysis on risk factors for critical hand, foot and mouth disease AN - 920789186; 16083062 AB - Aim: To explore the risk factors from severe type to critical type of hand, foot and mouth disease (HFMD), and provide the reference for the clinical diagnosis of HFMD. Methods: A total of 455 sick children with HFMD treated in some Zhengzhou children hospital from January to December in 2009, were recruited and diagnosed severe illness (n = 366) and the critical illness (n = 89) groups according to their status. The information on clinical manifestations between the two groups was summarized and analyzed. Results: There were no differences in the age and the gender structure between the two groups (x super(2) = 0.268 and 7.639, P > 0.05). Multiple logistic regression analysis showed that only 11 risk factors were statistically significantly associated with the changing from severe illness to critical illness groups. Conclusion: A total of 11 clinical risk factors are identified to help predict the children at risk of critical HFMD. JF - Zhengzhou Daxue Xuebao (Yixue Ban) - Journal of Zhengzhou University. Medical sciences AU - Ru, W AU - Wang, Y AU - Kang, K AU - Wang, H AU - You, A AD - Institute of Infectious Disease Prevention and Control, Center for Disease Control and Prevention of Henan Province, Zhengzhou 450016, ruwp@hncdc.com.cn Y1 - 2011/07// PY - 2011 DA - Jul 2011 SP - 608 EP - 610 VL - 46 IS - 4 SN - 1671-6825, 1671-6825 KW - Risk Abstracts KW - Age KW - Risk factors KW - Gender KW - Children KW - Hospitals KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/920789186?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Zhengzhou+Daxue+Xuebao+%28Yixue+Ban%29+-+Journal+of+Zhengzhou+University.+Medical+sciences&rft.atitle=Analysis+on+risk+factors+for+critical+hand%2C+foot+and+mouth+disease&rft.au=Ru%2C+W%3BWang%2C+Y%3BKang%2C+K%3BWang%2C+H%3BYou%2C+A&rft.aulast=Ru&rft.aufirst=W&rft.date=2011-07-01&rft.volume=46&rft.issue=4&rft.spage=608&rft.isbn=&rft.btitle=&rft.title=Zhengzhou+Daxue+Xuebao+%28Yixue+Ban%29+-+Journal+of+Zhengzhou+University.+Medical+sciences&rft.issn=16716825&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-02-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Age; Risk factors; Gender; Children; Hospitals ER - TY - JOUR T1 - Prospective predictors of quitting behaviours among adult smokers in six cities in China: findings from the International Tobacco Control (ITC) China Survey AN - 920063738; 4266449 AB - Aim: To examine predictors of quitting behaviours among adult smokers in China, in light of existing knowledge from previous research in four western countries and two southeast Asian countries. Design: Face-to-face interviews were carried out with smokers in 2006 using the International Tobacco Control (ITC) China Survey, with follow-up about 16 months later. A stratified multi-stage cluster sampling design was employed. Setting: Beijing and five other cities in China. Participants: A total of 4732 smokers were first surveyed in 2006. Of these, 3863 were re-contacted in 2007, with a retention rate of 81.6%. Measurements: Baseline measures of socio-demographics, dependence and interest in quitting were used prospectively to predict both making quit attempts and staying quit among those who attempted. Findings: Overall, 25.3% Chinese smokers reported having made at least one quit attempt between waves 1 and 2; of these, 21.7% were still stopped at wave 2. Independent predictors of making quit attempts included having higher quitting self-efficacy, previous quit attempts, more immediate intentions to quit, longer time to first cigarette upon waking, negative opinion of smoking and having smoking restrictions at home. Independent predictors of staying quit were being older, having longer previous abstinence from smoking and having more immediate quitting intentions. Conclusions: Predictors of Chinese smokers' quitting behaviours are somewhat different to those found in previous research from other countries. Nicotine dependence and self-efficacy seem to be more important for attempts than for staying quit in China, and quitting intentions are related to both attempts and staying quit. Reprinted by permission of Blackwell Publishing JF - Addiction AU - Yong, Hua-hie AU - Borland, Ron AU - Fong, Geoffrey T AU - Li, Lin AU - Feng, Guoze AU - Jiang, Yuan AD - Cancer Council Victoria ; Chinese Center for Disease Control and Prevention ; University of Waterloo Y1 - 2011/07// PY - 2011 DA - Jul 2011 SP - 1335 EP - 1345 VL - 106 IS - 7 SN - 0965-2140, 0965-2140 KW - Sociology KW - Smoking KW - Behavioural psychology KW - Tobacco KW - Surveys KW - Addiction KW - Adults KW - Drug addiction KW - China KW - Urban areas UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/920063738?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Addiction&rft.atitle=Prospective+predictors+of+quitting+behaviours+among+adult+smokers+in+six+cities+in+China%3A+findings+from+the+International+Tobacco+Control+%28ITC%29+China+Survey&rft.au=Yong%2C+Hua-hie%3BBorland%2C+Ron%3BFong%2C+Geoffrey+T%3BLi%2C+Lin%3BFeng%2C+Guoze%3BJiang%2C+Yuan&rft.aulast=Yong&rft.aufirst=Hua-hie&rft.date=2011-07-01&rft.volume=106&rft.issue=7&rft.spage=1335&rft.isbn=&rft.btitle=&rft.title=Addiction&rft.issn=09652140&rft_id=info:doi/10.1111%2Fj.1360-0443.2011.03444.x LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 12429; 603; 1540 1543 10404; 561 6220; 12766 3055 798 10286; 11755 5707 6071 1542 11325; 13161 1247; 3744 561 6220; 93 116 30 DO - http://dx.doi.org/10.1111/j.1360-0443.2011.03444.x ER - TY - JOUR T1 - Physical ergonomic hazards in highway tunnel construction: Overview from the Construction Occupational Health Program AN - 910638278; 14767532 AB - This report provides an overview of physical ergonomic exposures in highway construction work across trades and major operations. For each operation, the observational method "PATH" (Posture, Activity, Tools and Handling) was used to estimate the percentage of time that workers spent in specific tasks and with exposure to awkward postures and load handling. The observations were carried out on 73 different days, typically for about 4 h per day, covering 120 construction workers in 5 different trades: laborers, carpenters, ironworkers, plasterers, and tilers. Non-neutral trunk postures (forward or sideways flexion or twisting) were frequently observed, representing over 40% of observations for all trades except laborers (28%). Kneeling and squatting were common in all operations, especially tiling and underground utility relocation work. Handling loads was frequent, especially for plasterers and tilers, with a range of load weights but most often under 15 pounds. The results of this study provide quantitative evidence that workers in highway tunnel construction operations are exposed to ergonomic factors known to present significant health hazards. Numerous opportunities exist for the development and implementation of ergonomic interventions to protect the health and safety of construction workers. JF - Applied Ergonomics AU - Tak, SangWoo AU - Buchholz, Bryan AU - Punnett, Laura AU - Moir, Susan AU - Paquet, Victor AU - Fulmer, Scott AU - Marucci-Wellman, Helen AU - Wegman, David Y1 - 2011/07// PY - 2011 DA - Jul 2011 SP - 665 EP - 671 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 42 IS - 5 SN - 0003-6870, 0003-6870 KW - Health & Safety Science Abstracts KW - Construction industry KW - working conditions KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/910638278?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+Ergonomics&rft.atitle=Physical+ergonomic+hazards+in+highway+tunnel+construction%3A+Overview+from+the+Construction+Occupational+Health+Program&rft.au=Tak%2C+SangWoo%3BBuchholz%2C+Bryan%3BPunnett%2C+Laura%3BMoir%2C+Susan%3BPaquet%2C+Victor%3BFulmer%2C+Scott%3BMarucci-Wellman%2C+Helen%3BWegman%2C+David&rft.aulast=Tak&rft.aufirst=SangWoo&rft.date=2011-07-01&rft.volume=42&rft.issue=5&rft.spage=665&rft.isbn=&rft.btitle=&rft.title=Applied+Ergonomics&rft.issn=00036870&rft_id=info:doi/10.1016%2Fj.apergo.2010.10.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - working conditions DO - http://dx.doi.org/10.1016/j.apergo.2010.10.001 ER - TY - JOUR T1 - Methicillin-resistant Staphylococcus aureus colonization in HIV-infected outpatients is common and detection is enhanced by groin culture AN - 902354392; 15768930 AB - Although high rates of clinical infection with methicillin-resistant Staphylococcus aureus (MRSA) have been reported in HIV-infected adults, data on MRSA colonization are limited. We enrolled HIV-infected adults receiving care at the Atlanta VA Medical Center. Swabs from each participant's nares and groin were cultured with broth enrichment for S. aureus. Of 600 HIV-infected adults, 79 (13%) were colonized with MRSA and 180 (30%) with methicillin-susceptible S. aureus. MRSA pulsed-field gel electrophoresis types USA300 (n=44, 54%) and USA500/Iberian (n=29, 35%) predominated. Inclusion of groin swabs increased MRSA detection by 24% and USA300 detection by 38%. In multivariate analysis, MRSA colonization compared to no MRSA colonization was associated with a history of MRSA clinical infection, rarely or never using condoms, and contact with prisons and jails. In summary, the prevalence of MRSA colonization was high in this study of HIV-infected adults and detection of USA300 was enhanced by groin culture. JF - Epidemiology and Infection AU - Peters, P J AU - Brooks, J T AU - Limbago, B AU - Lowery, H K AU - McALLISTER, S K AU - MINDLEY, R AU - Fosheim, G AU - GORWITZ, R J AU - Guest, J L AU - Hageman, J AU - FRIDGE, J AU - Rimland, D AD - Centers for Disease Control and Prevention, Atlanta, GA, USA, pjpeters@cdc.gov pjpeters@cdc.gov pjpeters@cdc.gov pjpeters@cdc.gov pjpeters@cdc.gov pjpeters@cdc.gov pjpeters@cdc.gov pjpeters@cdc.gov pjpeters@cdc.gov pjpeters@cdc.gov pjpeters@cdc.gov Y1 - 2011/07// PY - 2011 DA - Jul 2011 SP - 998 EP - 1008 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU United Kingdom VL - 139 IS - 7 SN - 0950-2688, 0950-2688 KW - Microbiology Abstracts B: Bacteriology; Health & Safety Science Abstracts KW - Historical account KW - Prisons KW - Electrophoresis KW - Data processing KW - antibiotic resistance KW - Drug resistance KW - Infection KW - colonization KW - prisons KW - Condoms KW - Spain, Galicia KW - Colonization KW - Human immunodeficiency virus KW - Multivariate analysis KW - infection KW - condoms KW - Pulsed-field gel electrophoresis KW - USA, Georgia, Atlanta KW - Staphylococcus aureus KW - H 11000:Diseases/Injuries/Trauma KW - J 02300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/902354392?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Methicillin-resistant+Staphylococcus+aureus+colonization+in+HIV-infected+outpatients+is+common+and+detection+is+enhanced+by+groin+culture&rft.au=Peters%2C+P+J%3BBrooks%2C+J+T%3BLimbago%2C+B%3BLowery%2C+H+K%3BMcALLISTER%2C+S+K%3BMINDLEY%2C+R%3BFosheim%2C+G%3BGORWITZ%2C+R+J%3BGuest%2C+J+L%3BHageman%2C+J%3BFRIDGE%2C+J%3BRimland%2C+D&rft.aulast=Peters&rft.aufirst=P&rft.date=2011-07-01&rft.volume=139&rft.issue=7&rft.spage=998&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268810002013 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Number of references - 2 N1 - Last updated - 2013-07-26 N1 - SubjectsTermNotLitGenreText - Condoms; Prisons; Colonization; Data processing; Multivariate analysis; Drug resistance; Pulsed-field gel electrophoresis; Infection; prisons; Historical account; Electrophoresis; antibiotic resistance; condoms; infection; colonization; Human immunodeficiency virus; Staphylococcus aureus; Spain, Galicia; USA, Georgia, Atlanta DO - http://dx.doi.org/10.1017/S0950268810002013 ER - TY - JOUR T1 - Diabetes and tuberculosis, US National Health Interview Survey, 2000-2005 AN - 899153340; 15220563 AB - Blacks and Hispanics are disproportionately affected by diabetes, which may confound ethnic association with tuberculosis (TB). We analyzed 2000-2005 National Health Interview Survey data. We present adjusted odds ratios (aORs) and 99% confidence intervals (CIs) for the association of diabetes with history of TB disease, controlling for race/ethnicity and age. Diabetics had an aOR of 1.4 (99%CI 1.0-2.0) for history of TB, controlling for being foreign-born non-Hispanic (aOR 2.2, 99%CI 1.6-3.2), US-born Hispanic (aOR 2.1, 99%CI 1.4-3.2), age less than or equal to 65 years (aOR 2.0, 99%CI 1.5-2.6), and being Black (aOR 1.6, 99%CI 1.1-2.4). After controlling for race/ethnicity, self-identified diabetics had an increased aOR for history of TB. JF - International Journal of Tuberculosis and Lung Disease AU - Marks, S M AD - Centers for Disease Control and Prevention/National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention/Division of Tuberculosis Elimination, Mailstop E-10, 1600 Clifton Road NE, Atlanta, GA 30333, USA, Smarks@cdc.gov Y1 - 2011/07// PY - 2011 DA - Jul 2011 SP - 982 EP - 984 PB - International Union Against Tuberculosis and Lung Disease VL - 15 IS - 7 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology KW - Diabetes mellitus KW - Age KW - Data processing KW - Mycobacterium KW - Lung diseases KW - Tuberculosis KW - Ethnic groups KW - Races KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/899153340?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Diabetes+and+tuberculosis%2C+US+National+Health+Interview+Survey%2C+2000-2005&rft.au=Marks%2C+S+M&rft.aulast=Marks&rft.aufirst=S&rft.date=2011-07-01&rft.volume=15&rft.issue=7&rft.spage=982&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/10.5588%2Fijtld.10.0637 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Diabetes mellitus; Age; Data processing; Lung diseases; Tuberculosis; Races; Ethnic groups; Mycobacterium DO - http://dx.doi.org/10.5588/ijtld.10.0637 ER - TY - JOUR T1 - Transmission Efficiency of Francisella tularensis by Adult American Dog Ticks (Acari: Ixodidae) AN - 893275665; 15466578 AB - The American dog tick, Dermacentor variabilis (Say) (Acari: Ixodidae), has been implicated as a potential bridging vector to humans of Francisella tularensis, the etiological agent of tularemia. Since the initial studies evaluating vector competency of D. variabilis were conducted, F. tularensis has been subdivided into subspecies and clades that differ in their geographical distribution in the United States and in the severity of infections caused in humans. Here, we demonstrate that D. variabilis nymphs efficiently acquire, transtadially maintain, and transmit each of the strains tested (clades A1b and A2, and type B). Transmission efficiency by adult females was similarly high among infection groups and ranged from 58% for type B to 89% for A2 infections. In addition, we demonstrated that transmission can occur shortly after tick attachment. These findings support the concept that D. variabilis adults may play a significant role in epizootic transmission of F. tularensis, and as a bridging vector to humans. JF - Journal of Medical Entomology AU - Reese, Sara M AU - Petersen, Jeannine M AU - Sheldon, Sarah W AU - Dolan, Marc C AU - Dietrich, Gabrielle AU - Piesman, Joseph AU - Eisen, Rebecca J Y1 - 2011/07// PY - 2011 DA - Jul 2011 SP - 884 EP - 890 PB - Entomological Society of America, 9301 Annapolis Rd. Lanham MD 20706 United States VL - 48 IS - 4 SN - 0022-2585, 0022-2585 KW - Microbiology Abstracts B: Bacteriology; Entomology Abstracts KW - Disease transmission KW - Epizootics KW - Geographical distribution KW - Infection KW - Tularemia KW - Vectors KW - Ixodidae KW - Dermacentor variabilis KW - Francisella tularensis KW - Acari KW - J 02410:Animal Diseases KW - Z 05350:Medical, Veterinary, and Agricultural Entomology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/893275665?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Medical+Entomology&rft.atitle=Transmission+Efficiency+of+Francisella+tularensis+by+Adult+American+Dog+Ticks+%28Acari%3A+Ixodidae%29&rft.au=Reese%2C+Sara+M%3BPetersen%2C+Jeannine+M%3BSheldon%2C+Sarah+W%3BDolan%2C+Marc+C%3BDietrich%2C+Gabrielle%3BPiesman%2C+Joseph%3BEisen%2C+Rebecca+J&rft.aulast=Reese&rft.aufirst=Sara&rft.date=2011-07-01&rft.volume=48&rft.issue=4&rft.spage=884&rft.isbn=&rft.btitle=&rft.title=Journal+of+Medical+Entomology&rft.issn=00222585&rft_id=info:doi/10.1603%2FME11005 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-09-01 N1 - Number of references - 2 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - Geographical distribution; Tularemia; Vectors; Epizootics; Infection; Disease transmission; Ixodidae; Francisella tularensis; Dermacentor variabilis; Acari DO - http://dx.doi.org/10.1603/ME11005 ER - TY - JOUR T1 - Insecticide susceptibility and resistance of Culex tritaeniorhynchus (Diptera: Culicidae) larvae collected from Gwangju, Republic of Korea AN - 888113605; 15451093 AB - The susceptibility of Culex tritaeniorhynchus collected from Gwangju, Jeollabuk Province, Republic of Korea (ROK) to insecticides was evaluated under laboratory conditions using ten insecticides (7 pyrethroids and 3 organophosphates) that are currently applied by local public health centers in the ROK. Based on the values of median lethal concentration (LC50), Cx. tritaeniorhynchus larvae were most susceptible to chlorpyrifos (0.006ppm), fenitrothion (0.022ppm), fenthion (0.035ppm) and bifenthrin (0.038ppm), and were least susceptible to esbiol (1.722ppm). In comparative resistance tests, the resistance ratios (RRs) of seven insecticides were compared among each other using two strains of Cx. tritaeniorhynchus that were collected from the same locality during 1992 and 2010. Culex tritaeniorhynchus demonstrated significantly increased RRs to pyrethroids over time, while demonstrating decreased RRs among the organophosphates. Among the pyrethroids, permethrin had the highest RR values of 182.1- and 833.3-fold differences, followed by etofenprox with RRs of 138.4- and 224.1-fold differences in values of LC50 and concentration that produced 90% mortality (LC90), respectively. Culex tritaeniorhynchus strains demonstrated the least amount of change in susceptibility to the organophosphates, chlorpyrifos, fenitrothion and fenthion with 0.020-, 0.019- and 0.001-fold differences in resistance ratios (RRLC50), respectively. JF - Entomological Research AU - SHIN, E Hyun AU - KIM, Hyun Kyung AU - PARK, Chan AU - LEE, Dong-Kyu AU - KANG, Hyesook AU - CHANG, Kyu Sik AD - National Institute of Health, Korea Center for Disease Control and Prevention, Chungbuk, Korea Y1 - 2011/07// PY - 2011 DA - Jul 2011 SP - 157 EP - 160 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 41 IS - 4 SN - 1738-2297, 1738-2297 KW - Entomology Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Mortality KW - Permethrin KW - Culicidae KW - Pest control KW - organophosphates KW - Fenitrothion KW - Fenthion KW - Strains KW - Toxicity tests KW - Public health KW - Chlorpyrifos KW - Insecticides KW - Culex tritaeniorhynchus KW - Insect larvae KW - Pesticides KW - Korea, Rep. KW - Pyrethroids KW - Diptera KW - Aquatic insects KW - Mortality causes KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - Q1 08485:Species interactions: pests and control KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/888113605?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Entomological+Research&rft.atitle=Insecticide+susceptibility+and+resistance+of+Culex+tritaeniorhynchus+%28Diptera%3A+Culicidae%29+larvae+collected+from+Gwangju%2C+Republic+of+Korea&rft.au=SHIN%2C+E+Hyun%3BKIM%2C+Hyun+Kyung%3BPARK%2C+Chan%3BLEE%2C+Dong-Kyu%3BKANG%2C+Hyesook%3BCHANG%2C+Kyu+Sik&rft.aulast=SHIN&rft.aufirst=E&rft.date=2011-07-01&rft.volume=41&rft.issue=4&rft.spage=157&rft.isbn=&rft.btitle=&rft.title=Entomological+Research&rft.issn=17382297&rft_id=info:doi/10.1111%2Fj.1748-5967.2011.00328.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-09-01 N1 - Document feature - figure 0 N1 - Last updated - 2014-12-11 N1 - SubjectsTermNotLitGenreText - Insecticides; Insect larvae; Pesticides; Pest control; Strains; Toxicity tests; Aquatic insects; Mortality causes; Public health; Chlorpyrifos; Mortality; Permethrin; Fenitrothion; organophosphates; Fenthion; Pyrethroids; Culex tritaeniorhynchus; Culicidae; Diptera; Korea, Rep. DO - http://dx.doi.org/10.1111/j.1748-5967.2011.00328.x ER - TY - JOUR T1 - Smoking status and urine cadmium above levels associated with subclinical renal effects in U.S. adults without chronic kidney disease AN - 888102685; 15458634 AB - Tobacco smoke is a major source of adult exposure to cadmium (Cd). Urine Cd levels (CdU) above 1.0, 0.7, and 0.5 mu g Cd/g creatinine have been associated with increased rates of microproteinuria and reduction in glomerular filtration rate. The two study objectives were to determine the prevalence and relative risk (RR) by smoking status for CdU above 1.0, 0.7, and 0.5 mu g Cd/g creatinine in U.S. adults; and to describe geometric mean CdU by smoking status, age, and sex. NHANES 1999-2006 data for adults without chronic kidney disease were used to compute prevalence rates above the three CdU in current and former cigarette smokers, and non-smokers. RRs for smokers adjusted for age and sex were computed by logistic regression. Analysis of covariance was used to calculate geometric means of CdU adjusted for age, sex, smoking status, log urine creatinine, and interaction terms: age-smoking status and sex-smoking status. At selected ages, adjusted RR for exceeding each risk-associated CdU was highest for current smokers (3-13 times), followed by former smokers (2-3 times), compared to non-smokers. Adjusted RR for smokers increased with age and was higher in females than males. Adjusted geometric means of CdUs increased with age, were higher in females than in males regardless of smoking status, and were higher in current smokers than former smokers, who had higher levels than non-smokers at any age. Cigarette smoking greatly increases RR of exceeding renal risk-associated CdU. Former smokers retain significant risk of exceeding these levels compared to non-smokers. CdU increased with age, particularly in current smokers. JF - International Journal of Hygiene and Environmental Health AU - Mortensen, Mary Ellen AU - Wong, Lee-Yang AU - Osterloh, John D Y1 - 2011/07// PY - 2011 DA - Jul 2011 SP - 305 EP - 310 PB - Elsevier B.V., P.O. Box 100537 Jena D-07705 Germany VL - 214 IS - 4 SN - 1438-4639, 1438-4639 KW - Environment Abstracts; Risk Abstracts KW - Smoke KW - USA KW - Age KW - Filtration KW - Cigarettes KW - Urine KW - Kidney KW - Tobacco KW - R2 23060:Medical and environmental health KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/888102685?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Hygiene+and+Environmental+Health&rft.atitle=Smoking+status+and+urine+cadmium+above+levels+associated+with+subclinical+renal+effects+in+U.S.+adults+without+chronic+kidney+disease&rft.au=Mortensen%2C+Mary+Ellen%3BWong%2C+Lee-Yang%3BOsterloh%2C+John+D&rft.aulast=Mortensen&rft.aufirst=Mary&rft.date=2011-07-01&rft.volume=214&rft.issue=4&rft.spage=305&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Hygiene+and+Environmental+Health&rft.issn=14384639&rft_id=info:doi/10.1016%2Fj.ijheh.2011.03.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-09-01 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - Smoke; Filtration; Age; Cigarettes; Urine; Tobacco; Kidney; USA DO - http://dx.doi.org/10.1016/j.ijheh.2011.03.004 ER - TY - JOUR T1 - Genetic Evidence for Rift Valley Fever Outbreaks in Madagascar Resulting from Virus Introductions from the East African Mainland rather than Enzootic Maintenance AN - 888098230; 15404415 AB - Rift Valley fever virus (RVFV), a mosquito-borne phlebovirus, has been detected in Madagascar since 1979, with occasional outbreaks. In 2008 to 2009, a large RVFV outbreak was detected in Malagasy livestock and humans during two successive rainy seasons. To determine whether cases were due to enzootic maintenance of the virus within Madagascar or to importation from the East African mainland, nine RVFV whole genomic sequences were generated for viruses from the 1991 and 2008 Malagasy outbreaks. Bayesian coalescent analyses of available whole S, M, and L segment sequences were used to estimate the time to the most recent common ancestor for the RVFVs. The 1979 Madagascar isolate shared a common ancestor with strains on the mainland around 1972. The 1991 Madagascar isolates were in a clade distinct from that of the 1979 isolate and shared a common ancestor around 1987. Finally, the 2008 Madagascar viruses were embedded within a large clade of RVFVs from the 2006-2007 outbreak in East Africa and shared a common ancestor around 2003 to 2004. These results suggest that the most recent Madagascar outbreak was caused by a virus likely arriving in the country some time between 2003 and 2008 and that this outbreak may be an extension of the 2006-2007 East African outbreak. Clustering of the Malagasy sequences into subclades indicates that the viruses have continued to evolve during their short-term circulation within the country. These data are consistent with the notion that RVFV outbreaks in Madagascar result not from emergence from enzootic cycles within the country but from recurrent virus introductions from the East African mainland. JF - Journal of Virology AU - Carroll, Serena A AU - Reynes, Jean-Marc AU - Khristova, Marina L AU - Andriamandimby, Soa Fy AU - Rollin, Pierre E AU - Nichol, Stuart T AD - Viral Special Pathogens Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, 1600 Clifton Road, MS G-14, snichol@cdc.gov Y1 - 2011/07// PY - 2011 DA - July 2011 SP - 6162 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 85 IS - 13 SN - 0022-538X, 0022-538X KW - ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Genetics Abstracts; Virology & AIDS Abstracts KW - Virology KW - Data processing KW - Bayesian analysis KW - Viruses KW - Rift Valley fever KW - Importation KW - Strains KW - Phlebovirus KW - Livestock KW - Public health KW - Rainy season KW - ISW, Indian Ocean, Madagascar KW - Africa KW - Rift Valley fever virus KW - genomics KW - Rift valleys KW - Aquatic insects KW - Q1 08205:Genetics and evolution KW - Q5 08524:Public health, medicines, dangerous organisms KW - G 07760:Viruses & Phages KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/888098230?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Virology&rft.atitle=Genetic+Evidence+for+Rift+Valley+Fever+Outbreaks+in+Madagascar+Resulting+from+Virus+Introductions+from+the+East+African+Mainland+rather+than+Enzootic+Maintenance&rft.au=Carroll%2C+Serena+A%3BReynes%2C+Jean-Marc%3BKhristova%2C+Marina+L%3BAndriamandimby%2C+Soa+Fy%3BRollin%2C+Pierre+E%3BNichol%2C+Stuart+T&rft.aulast=Carroll&rft.aufirst=Serena&rft.date=2011-07-01&rft.volume=85&rft.issue=13&rft.spage=6162&rft.isbn=&rft.btitle=&rft.title=Journal+of+Virology&rft.issn=0022538X&rft_id=info:doi/10.1128%2FJVI.00335-11 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-09-01 N1 - Number of references - 31 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Virology; Rainy season; Viruses; Strains; Aquatic insects; Rift valleys; Public health; Data processing; Bayesian analysis; Rift Valley fever; genomics; Importation; Livestock; Rift Valley fever virus; Phlebovirus; ISW, Indian Ocean, Madagascar; Africa DO - http://dx.doi.org/10.1128/JVI.00335-11 ER - TY - JOUR T1 - HIV Prevention Among African American Youth: How Well Have Evidence-Based Interventions Addressed Key Theoretical Constructs? AN - 883044989; 15164926 AB - Certain constructs are demonstrated in the research literature to be related to HIV risk behaviors among African American adolescents. This study examines how well these constructs are addressed in evidence-based interventions (EBIs) developed for this population. A literature review on variables for sexual risk behaviors among African American adolescents was undertaken. Simultaneously, a review was conducted of the contents of HIV-prevention EBIs. To facilitate comparison, findings from both were organized into constructs from prominent behavior change theories. Analysis showed that environmental conditions and perceived norms were frequently associated with sexual risk behaviors in the literature, while EBIs devoted considerable time to knowledge, skills, and self-efficacy. Findings imply that (a) EBIs might be complemented with activities that focus on important constructs identified in the literature and (b) researchers should better assess the relationship between skill development and HIV risk behaviors. Implications for practice and research are discussed. JF - AIDS and Behavior AU - Romero, Lisa M AU - Galbraith, Jennifer S AU - Wilson-Williams, Lyndsey AU - Gloppen, Kari M AD - Research Application Branch, Division of Adolescent and School Health, CDC, 4770 Buford Highway, NE, Mailstop K-12, Atlanta, GA, 30341, USA, lmromero@cdc.gov Y1 - 2011/07// PY - 2011 DA - Jul 2011 SP - 976 EP - 991 PB - Springer Science+Business Media, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 15 IS - 5 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Risk Abstracts KW - sexual behavior KW - Acquired immune deficiency syndrome KW - Adolescence KW - Development KW - Sexual behavior KW - Literature reviews KW - Human immunodeficiency virus KW - Perception KW - Reviews KW - intervention KW - prevention KW - Environmental conditions KW - Ethnic groups KW - Adolescents KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/883044989?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=HIV+Prevention+Among+African+American+Youth%3A+How+Well+Have+Evidence-Based+Interventions+Addressed+Key+Theoretical+Constructs%3F&rft.au=Romero%2C+Lisa+M%3BGalbraith%2C+Jennifer+S%3BWilson-Williams%2C+Lyndsey%3BGloppen%2C+Kari+M&rft.aulast=Romero&rft.aufirst=Lisa&rft.date=2011-07-01&rft.volume=15&rft.issue=5&rft.spage=976&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-010-9745-5 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-08-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Literature reviews; Adolescence; Development; Environmental conditions; Sexual behavior; sexual behavior; Acquired immune deficiency syndrome; Perception; Human immunodeficiency virus; intervention; Reviews; prevention; Adolescents; Ethnic groups DO - http://dx.doi.org/10.1007/s10461-010-9745-5 ER - TY - JOUR T1 - Mycobacterium tuberculosis components stimulate production of the antimicrobial peptide hepcidin AN - 883035333; 15324514 AB - We investigated the in vitro production of the antimicrobial peptide hepcidin by cells of the innate immune system that harbor Mycobacterium tuberculosis. Stimulation of mouse lung macrophages with M. tuberculosis or IFN- gamma + M. tuberculosis induced hepcidin mRNA. In human alveolar A549 epithelial cells, lipoglycans of M. tuberculosis, in particular mannose-capped lipoarabinomannan and phosphatidyl-myo-inositol mannosides, were strong inducers of hepcidin mRNA. In mouse dendritic cells, hepcidin mRNA was increased by subcellular fractions and culture filtrate proteins of M. tuberculosis and by TLR2 and TLR4 agonists, but not by TLR9 agonists, IL-1 alpha , IL-6 or TNF- alpha . Flow cytometry evaluation of human peripheral blood mononuclear cells demonstrated that CD11c super(+ myeloid dendritic cells stimulated with killed M. tuberculosis or live M. bovis BCG produced hepcidin. The production of the antimicrobial peptide hepcidin by cells that interact with M. tuberculosis suggests a host defense mechanism against mycobacteria.) JF - Tuberculosis AU - Sow, Fatoumata B AU - Nandakumar, Subhadra AU - Velu, Vijayakumar AU - Kellar, Kathryn L AU - Schlesinger, Larry S AU - Amara, Rama R AU - Lafuse, William P AU - Shinnick, Thomas M AU - Sable, Suraj B AD - Division of TB Elimination, National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, Atlanta GA 30333, USA Y1 - 2011/07// PY - 2011 DA - Jul 2011 SP - 314 EP - 321 PB - Harcourt Publishers Ltd., Robert Stevenson House Edinburgh EH1 3AF United Kingdom VL - 91 IS - 4 SN - 1472-9792, 1472-9792 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology KW - Alveoli KW - Antimicrobial peptides KW - BCG KW - CD11c antigen KW - Cell culture KW - Defense mechanisms KW - Dendritic cells KW - Epithelial cells KW - Flow cytometry KW - Hepcidin KW - Immune system KW - Interleukin 1 KW - Interleukin 6 KW - Lipoarabinomannans KW - Lung KW - Macrophages KW - Peripheral blood mononuclear cells KW - TLR2 protein KW - TLR4 protein KW - TLR9 protein KW - Toll-like receptors KW - Tuberculosis KW - Tumor necrosis factor- alpha KW - gamma -Interferon KW - mRNA KW - Mycobacterium tuberculosis KW - A 01340:Antibiotics & Antimicrobials KW - J 02350:Immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/883035333?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Tuberculosis&rft.atitle=Mycobacterium+tuberculosis+components+stimulate+production+of+the+antimicrobial+peptide+hepcidin&rft.au=Sow%2C+Fatoumata+B%3BNandakumar%2C+Subhadra%3BVelu%2C+Vijayakumar%3BKellar%2C+Kathryn+L%3BSchlesinger%2C+Larry+S%3BAmara%2C+Rama+R%3BLafuse%2C+William+P%3BShinnick%2C+Thomas+M%3BSable%2C+Suraj+B&rft.aulast=Sow&rft.aufirst=Fatoumata&rft.date=2011-07-01&rft.volume=91&rft.issue=4&rft.spage=314&rft.isbn=&rft.btitle=&rft.title=Tuberculosis&rft.issn=14729792&rft_id=info:doi/10.1016%2Fj.tube.2011.03.003 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-08-01 N1 - Last updated - 2012-09-10 N1 - SubjectsTermNotLitGenreText - Macrophages; Interleukin 6; gamma -Interferon; Epithelial cells; Immune system; TLR2 protein; Interleukin 1; Cell culture; CD11c antigen; Flow cytometry; Dendritic cells; Peripheral blood mononuclear cells; Tuberculosis; Hepcidin; TLR4 protein; TLR9 protein; Alveoli; mRNA; Lung; BCG; Tumor necrosis factor- alpha; Defense mechanisms; Antimicrobial peptides; Lipoarabinomannans; Toll-like receptors; Mycobacterium tuberculosis DO - http://dx.doi.org/10.1016/j.tube.2011.03.003 ER - TY - JOUR T1 - High-Throughput Sample Preparation for the Quantitation of Acephate, Methamidophos, Omethoate, Dimethoate, Ethylenethiourea, and Propylenethiourea in Human Urine Using 96-Well-Plate Automated Extraction and High-Performance Liquid Chromatography-Tandem Mass Spectrometry AN - 876238240; 14992085 AB - Acephate, methamidophos, o-methoate, and dimethoate are organophosphorus pesticides, and ethylenethiouria and propylenethiourea are two metabolites from the bisdithiocarbamate fungicide family. They are some of the most widely used pesticides and fungicides in agriculture both domestically and abroad. The existing high-performance liquid chromatography (HPLC)-tandem mass spectrometry (MS/MS) method for the measurement of these compounds in human urine was improved by using a 96-well plate format sample preparation; the use of HPLC-MS/MS was comparable with a concentration range of 0.125 to 50ng/ml. Deuterium-labeled acephate, ethylenethiouria, and methamidophos were used as internal standards. The sample preparation procedure, in the 96-well format with a 0.8-ml urine sample size, uses lyophilization of samples, followed by extraction with dichloromethane. The analytes were chromatographed on a Zorbax SB-C3 (4.6150mm, 5.0- mu m) column with gradient elution by using 0.1% formic acid in aqueous solution (solvent A) and 0.1% formic acid in methanol (solvent B) mobile phase at a flow rate of 1ml/min. Quantitative analysis was performed by atmospheric pressure chemical ionization source in positive ion mode using multiple-reaction monitoring of the precursor-to-product ion pairs for the analytes on a TSQ Quantum Ultra HPLC-MS/MS. Repeated analyses of urine samples spiked with high (15ng/ml), medium (5ng/ml), and low (1ng/ml) concentrations of the analytes gave relative SDs of <13%. The limits of detection were in the range of 0.004-0.01ng/ml. The method also has high accuracy, high precision, and excellent extraction recovery. Furthermore, the improved sample preparation method decreased the cost and labor required while effectively doubling the analytic throughput with minimal matrix effect. JF - Archives of Environmental Contamination and Toxicology AU - Jayatilaka, Nayana K AU - Angela Montesano, M AU - Whitehead, Ralph D AU - Schloth, Sara J AU - Needham, Larry L AU - Barr, Dana Boyd AD - Centers for Disease Control and Prevention, Atlanta, GA, 30341, USA, AHM2@cdc.gov Y1 - 2011/07// PY - 2011 DA - July 2011 SP - 59 EP - 67 PB - Springer-Verlag, 175 Fifth Ave. New York NY 10010 USA VL - 61 IS - 1 SN - 0090-4341, 0090-4341 KW - Health & Safety Science Abstracts; Environment Abstracts; Pollution Abstracts; Toxicology Abstracts KW - Agriculture KW - High-performance liquid chromatography KW - Methanol KW - Mass spectrometry KW - Metabolites KW - Freeze-drying KW - omethoate KW - Mass spectroscopy KW - Quantitation KW - Pesticides (organophosphorus) KW - methamidophos KW - Quantitative analysis KW - Solvents KW - Formic acid KW - Dichloromethane KW - Urine KW - Fungicides KW - Pesticides KW - atmospheric pressure KW - Atmospheric pressure KW - Dimethoate KW - dimethoate KW - Ionization KW - P 0000:AIR POLLUTION KW - H 5000:Pesticides KW - X 24330:Agrochemicals KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/876238240?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Archives+of+Environmental+Contamination+and+Toxicology&rft.atitle=High-Throughput+Sample+Preparation+for+the+Quantitation+of+Acephate%2C+Methamidophos%2C+Omethoate%2C+Dimethoate%2C+Ethylenethiourea%2C+and+Propylenethiourea+in+Human+Urine+Using+96-Well-Plate+Automated+Extraction+and+High-Performance+Liquid+Chromatography-Tandem+Mass+Spectrometry&rft.au=Jayatilaka%2C+Nayana+K%3BAngela+Montesano%2C+M%3BWhitehead%2C+Ralph+D%3BSchloth%2C+Sara+J%3BNeedham%2C+Larry+L%3BBarr%2C+Dana+Boyd&rft.aulast=Jayatilaka&rft.aufirst=Nayana&rft.date=2011-07-01&rft.volume=61&rft.issue=1&rft.spage=59&rft.isbn=&rft.btitle=&rft.title=Archives+of+Environmental+Contamination+and+Toxicology&rft.issn=00904341&rft_id=info:doi/10.1007%2Fs00244-010-9593-3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-07-01 N1 - Last updated - 2016-02-04 N1 - SubjectsTermNotLitGenreText - High-performance liquid chromatography; Agriculture; Pesticides (organophosphorus); methamidophos; Methanol; Solvents; Metabolites; Freeze-drying; omethoate; Mass spectroscopy; Dichloromethane; Formic acid; Urine; Pesticides; Fungicides; Atmospheric pressure; Dimethoate; Ionization; Quantitation; Quantitative analysis; atmospheric pressure; Mass spectrometry; dimethoate DO - http://dx.doi.org/10.1007/s00244-010-9593-3 ER - TY - JOUR T1 - The International Collaboration on Air Pollution and Pregnancy Outcomes: initial results. AN - 874486429; 21306972 AB - The findings of prior studies of air pollution effects on adverse birth outcomes are difficult to synthesize because of differences in study design. The International Collaboration on Air Pollution and Pregnancy Outcomes was formed to understand how differences in research methods contribute to variations in findings. We initiated a feasibility study to a) assess the ability of geographically diverse research groups to analyze their data sets using a common protocol and b) perform location-specific analyses of air pollution effects on birth weight using a standardized statistical approach. Fourteen research groups from nine countries participated. We developed a protocol to estimate odds ratios (ORs) for the association between particulate matter ≤ 10 μm in aerodynamic diameter (PM₁₀) and low birth weight (LBW) among term births, adjusted first for socioeconomic status (SES) and second for additional location-specific variables. Among locations with data for the PM₁₀ analysis, ORs estimating the relative risk of term LBW associated with a 10-μg/m³ increase in average PM₁₀ concentration during pregnancy, adjusted for SES, ranged from 0.63 [95% confidence interval (CI), 0.30-1.35] for the Netherlands to 1.15 (95% CI, 0.61-2.18) for Vancouver, with six research groups reporting statistically significant adverse associations. We found evidence of statistically significant heterogeneity in estimated effects among locations. Variability in PM₁₀-LBW relationships among study locations remained despite use of a common statistical approach. A more detailed meta-analysis and use of more complex protocols for future analysis may uncover reasons for heterogeneity across locations. However, our findings confirm the potential for a diverse group of researchers to analyze their data in a standardized way to improve understanding of air pollution effects on birth outcomes. JF - Environmental health perspectives AU - Parker, Jennifer D AU - Rich, David Q AU - Glinianaia, Svetlana V AU - Leem, Jong Han AU - Wartenberg, Daniel AU - Bell, Michelle L AU - Bonzini, Matteo AU - Brauer, Michael AU - Darrow, Lyndsey AU - Gehring, Ulrike AU - Gouveia, Nelson AU - Grillo, Paolo AU - Ha, Eunhee AU - van den Hooven, Edith H AU - Jalaludin, Bin AU - Jesdale, Bill M AU - Lepeule, Johanna AU - Morello-Frosch, Rachel AU - Morgan, Geoffrey G AU - Slama, Rémy AU - Pierik, Frank H AU - Pesatori, Angela Cecilia AU - Sathyanarayana, Sheela AU - Seo, Juhee AU - Strickland, Matthew AU - Tamburic, Lillian AU - Woodruff, Tracey J AD - National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, Maryland 20782, USA. jdparker@cdc.gov Y1 - 2011/07// PY - 2011 DA - July 2011 SP - 1023 EP - 1028 VL - 119 IS - 7 KW - Particulate Matter KW - 0 KW - Index Medicus KW - Birth Weight KW - Infant, Low Birth Weight KW - Humans KW - Particle Size KW - Infant, Newborn KW - Pilot Projects KW - Research Design KW - Pregnancy KW - Socioeconomic Factors KW - Feasibility Studies KW - International Cooperation KW - Risk Factors KW - Cohort Studies KW - Female KW - Premature Birth -- chemically induced KW - Particulate Matter -- toxicity KW - Air Pollution -- statistics & numerical data KW - Air Pollution -- adverse effects KW - Particulate Matter -- analysis KW - Premature Birth -- epidemiology KW - Pregnancy Outcome UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/874486429?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+health+perspectives&rft.atitle=The+International+Collaboration+on+Air+Pollution+and+Pregnancy+Outcomes%3A+initial+results.&rft.au=Parker%2C+Jennifer+D%3BRich%2C+David+Q%3BGlinianaia%2C+Svetlana+V%3BLeem%2C+Jong+Han%3BWartenberg%2C+Daniel%3BBell%2C+Michelle+L%3BBonzini%2C+Matteo%3BBrauer%2C+Michael%3BDarrow%2C+Lyndsey%3BGehring%2C+Ulrike%3BGouveia%2C+Nelson%3BGrillo%2C+Paolo%3BHa%2C+Eunhee%3Bvan+den+Hooven%2C+Edith+H%3BJalaludin%2C+Bin%3BJesdale%2C+Bill+M%3BLepeule%2C+Johanna%3BMorello-Frosch%2C+Rachel%3BMorgan%2C+Geoffrey+G%3BSlama%2C+R%C3%A9my%3BPierik%2C+Frank+H%3BPesatori%2C+Angela+Cecilia%3BSathyanarayana%2C+Sheela%3BSeo%2C+Juhee%3BStrickland%2C+Matthew%3BTamburic%2C+Lillian%3BWoodruff%2C+Tracey+J&rft.aulast=Parker&rft.aufirst=Jennifer&rft.date=2011-07-01&rft.volume=119&rft.issue=7&rft.spage=1023&rft.isbn=&rft.btitle=&rft.title=Environmental+health+perspectives&rft.issn=1552-9924&rft_id=info:doi/10.1289%2Fehp.1002725 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-10-24 N1 - Date created - 2011-07-01 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Epidemiology. 2009 Sep;20(5):699-706 [19535987] Epidemiology. 2009 Sep;20(5):689-98 [19478670] Environ Res. 2010 Jan;110(1):55-61 [19878932] Environ Health. 2009;8:59 [20028508] Environ Health. 2010;9:6 [20113501] Int J Environ Res Public Health. 2010 Jun;7(6):2638-52 [20644693] Environ Health. 2010;9:44 [20667084] Environ Health Perspect. 2010 Oct;118(10):1483-9 [20472526] Environ Res. 2011 Jan;111(1):125-35 [21067713] Environ Health. 2007;6:16 [17553174] Environ Health Perspect. 2007 Jul;115(7):1118-24 [17637932] Environ Health Perspect. 2007 Sep;115(9):1283-92 [17805417] Basic Clin Pharmacol Toxicol. 2008 Feb;102(2):182-90 [18226073] Am J Epidemiol. 2000 Sep 1;152(5):397-406 [10981451] Ann Epidemiol. 2002 Aug;12(6):410-8 [12160600] J Expo Anal Environ Epidemiol. 2003 Mar;13(2):134-43 [12679793] Environ Health Perspect. 2003 Jun;111(7):942-6 [12782496] Environ Health Perspect. 2003 Dec;111(16):1861-70 [14644658] J Epidemiol Community Health. 2004 Jan;58(1):11-7 [14684720] Epidemiology. 2004 Jan;15(1):36-45 [14712145] J Expo Anal Environ Epidemiol. 2004 Sep;14(5):391-6 [15361898] Ann Epidemiol. 1994 Jul;4(4):271-8 [7921316] Environ Health Perspect. 2005 Apr;113(4):375-82 [15811825] Occup Environ Med. 2005 Aug;62(8):524-30 [16046604] Environ Health Perspect. 2005 Sep;113(9):1212-21 [16140630] Epidemiology. 2005 Nov;16(6):727-36 [16222161] Environ Health Perspect. 2007 Feb;115(2):176-81 [17384761] Environ Health Perspect. 2008 May;116(5):680-6 [18470315] J Air Waste Manag Assoc. 2008 May;58(5):711-20 [18512448] Environ Health Perspect. 2008 Jun;116(6):791-8 [18560536] BMC Pregnancy Childbirth. 2008;8:39 [18713457] BMC Pregnancy Childbirth. 2008;8:46 [18842145] Environ Res. 2009 Apr;109(3):311-20 [19215915] Int Arch Occup Environ Health. 2009 Apr;82(5):613-21 [18998152] J Epidemiol Community Health. 2009 Jun;63(6):500-4 [19228684] J Epidemiol Community Health. 2009 Jun;63(6):488-96 [19359274] Environ Health Perspect. 2009 Aug;117(8):1313-21 [19672414] Environ Res. 2010 Jan;110(1):118-22 [19863953] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1289/ehp.1002725 ER - TY - JOUR T1 - The need for health impact assessment in China: potential benefits for public health and steps forward AN - 869402134; 4199455 AB - Health impact assessment (HIA) is a useful tool to predict and estimate the potential health impact associated with programs, projects, and policies by comprehensively identifying relevant health determinants and their consequences. China is undergoing massive and rapid socio-economic changes leading to environment and population health challenges such as a large increase in non-communicable diseases, the emergence and re-emergence of infectious diseases, new health risks associated with environmental pollutants and escalating health inequality. These health issues are affected by multiple determinants which can be influenced by planned policies, programs, and projects. This paper discusses the needs for health impact assessment in China in order to minimize the negative health consequences from projects, programs and policies associated with rapid social and economic development. It first describes the scope of China's current impact assessment system and points out its inadequacy in meeting the requirements of population health protection and promotion. It then analyses the potential use of HIA and why China needs to develop and apply HIA as a tool to identify potential health impacts of proposed programs, projects and policies so as to influence decision-making early in the planning process. Thus, the paper recommends the development of HIA as a useful tool in China to enhance decision-making for the protection and promotion of population health. For this to happen, the paper outlines steps necessary for the establishment and successful implementation of HIA in China: beginning with the establishment of a HIA framework, followed by workforce capacity building, methodology design, and intersectoral collaboration and stakeholder engagement. All rights reserved, Elsevier JF - Environmental impact assessment review AU - Wu, Liming AU - Rutherford, S AU - Chu, C AD - Shanghai Municipal Center for Disease Control and Prevention Y1 - 2011/07// PY - 2011 DA - Jul 2011 SP - 420 EP - 424 VL - 31 IS - 4 SN - 0195-9255, 0195-9255 KW - Sociology KW - Environmental degradation KW - Environmental impact studies KW - Estimation KW - Health inequality KW - Health services KW - China KW - Methodology KW - Public health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/869402134?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+impact+assessment+review&rft.atitle=The+need+for+health+impact+assessment+in+China%3A+potential+benefits+for+public+health+and+steps+forward&rft.au=Wu%2C+Liming%3BRutherford%2C+S%3BChu%2C+C&rft.aulast=Wu&rft.aufirst=Liming&rft.date=2011-07-01&rft.volume=31&rft.issue=4&rft.spage=420&rft.isbn=&rft.btitle=&rft.title=Environmental+impact+assessment+review&rft.issn=01959255&rft_id=info:doi/10.1016%2Fj.eiar.2010.03.004 LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 10449 5772; 4325 3851 971; 7994; 4403 7854; 5792 10484; 4314 4313 4309; 5783 5772 6489; 93 116 30 DO - http://dx.doi.org/10.1016/j.eiar.2010.03.004 ER - TY - JOUR T1 - Toward Rubella Elimination in Poland: Need for Supplemental Immunization Activities, Enhanced Surveillance, and Further Integration with Measles Elimination Efforts AN - 1627970038; 20933481 AB - Background. All Member States of the World Health Organization (WHO) European Region have endorsed rubella elimination and congenital rubella syndrome (CRS) prevention. However, Poland has continued high levels of reported rubella. Methods. We reviewed rubella incidence in Poland since 1966 and analyzed national aggregated surveillance data from the period 2003-2008 and case-based data from 4 provinces from the period 2006-2008. We described CRS cases since 1997 and assessed maternal receipt of vaccine. We reviewed national vaccination coverage from 1992 through 2008. Results. Since 1966, rubella outbreaks have occurred every 4-6 years in Poland. Aggregate and case-based data from the period 2003-2008 indicate that rubella virus transmission has occurred across wide age ranges (from <1 year to 60 years), with disproportionately higher percentage of cases among adolescent boys. Of 18 children with reported CRS cases from 1997 through 2008, 15 (83%) of their mothers had not been vaccinated. Measles-mumps-rubella dose 1 vaccination coverage ranged from 97% to 99%. Conclusions. Poland had the highest incidence of rubella in the WHO European Region in 2007 and 2008. Rubella occurs predominantly in age and sex cohorts historically not included in vaccination recommendations. The risk for CRS continues. To achieve rubella elimination, supplemental immunization activities among adolescent boys are needed, as is integration with measles elimination efforts. JF - Journal of Infectious Diseases AU - Zimmerman, Laura AU - Rogalska, Justyna AU - Wannemuehler, Kathleen A AU - Haponiuk, Marzena AU - Kosek, Adam AU - Pauch, Ewa AU - Plonska, Elzbieta AU - Veltze, Daniel AU - Czarkowski, Miroslaw R AU - Buddh, Nilesh AU - Reef, Susan AU - Stefanoff, Pawel AD - Global Immunization Division, National Center for Immunization and Respiratory Diseases, Center for Disease Control and Prevention, 1600 Clifton Rd, MS E-61, Atlanta, GA 30333, laz5@cdc.gov Y1 - 2011/07/01/ PY - 2011 DA - 2011 Jul 01 SP - S389 EP - S395 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 204 SN - 0022-1899, 0022-1899 KW - Immunology Abstracts; Virology & AIDS Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - Risk assessment KW - Historical account KW - Age KW - Measles KW - Rubella KW - Disease transmission KW - Integration KW - Infectious diseases KW - Congenital rubella KW - Adolescents KW - Sex KW - Data processing KW - Adolescence KW - Children KW - Vaccination KW - Immunization KW - Rubella virus KW - Prevention KW - Poland KW - Reviews KW - Outbreaks KW - Vaccines KW - R2 23060:Medical and environmental health KW - F 06910:Microorganisms & Parasites KW - V 22400:Human Diseases KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1627970038?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Toward+Rubella+Elimination+in+Poland%3A+Need+for+Supplemental+Immunization+Activities%2C+Enhanced+Surveillance%2C+and+Further+Integration+with+Measles+Elimination+Efforts&rft.au=Zimmerman%2C+Laura%3BRogalska%2C+Justyna%3BWannemuehler%2C+Kathleen+A%3BHaponiuk%2C+Marzena%3BKosek%2C+Adam%3BPauch%2C+Ewa%3BPlonska%2C+Elzbieta%3BVeltze%2C+Daniel%3BCzarkowski%2C+Miroslaw+R%3BBuddh%2C+Nilesh%3BReef%2C+Susan%3BStefanoff%2C+Pawel&rft.aulast=Zimmerman&rft.aufirst=Laura&rft.date=2011-07-01&rft.volume=204&rft.issue=&rft.spage=S389&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjir082 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-11-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Age; Data processing; Measles; Adolescence; Children; Rubella; Vaccination; Disease transmission; Integration; Congenital rubella; Reviews; Vaccines; Sex; Risk assessment; Historical account; Prevention; Infectious diseases; Outbreaks; Immunization; Adolescents; Rubella virus; Poland DO - http://dx.doi.org/10.1093/infdis/jir082 ER - TY - JOUR T1 - Impairment of CD4 super(+) T Cell Polarization by Dengue Virus-Infected Dendritic Cells AN - 1642622829; 21007097 AB - Background. The production of type I interferon alpha/beta (IFN- alpha / beta ) is crucial to viral clearance during dengue virus (DENV) infection; however, in vitro-infected dendritic cells (DCs) exhibit a decreased capacity to respond to IFN- alpha / beta stimulation, and antigen-presenting cells (APCs) isolated from patients with acute DENV infection exhibit defects in T cell priming. Methods. In order to ascertain the stimulatory capacity of primary human monocyte-derived DCs infected with wild-type DENV isolates, representing a range of genotypes and disease outcomes, we cocultured infected DCs with allogeneic-naive CD4 super(+) T cells. The gene expression patterns of IFN- alpha / beta sensitive genes were quantitated to determine if the infected DCs displayed a blunted IFN- alpha / beta response. Results. DENV-infected DCs induced the initial proliferation of naive CD4 super(+) T cells but they remained nonpolarized in effector function. The expression of IFN- alpha / beta -stimulated genes was downregulated, revealing that the inhibition of IFN- alpha / beta signaling is conserved among endemic DENV serotype 2 strains. Conclusions. The failure of naive CD4 super(+) T cells to differentiate into IFN gamma-producing effector T cells when primed by DENV-infected DCs cannot be explained solely by a block in IFN- alpha / beta signaling, suggesting that the ability of DENV to evade the early host response is multifaceted. JF - Journal of Infectious Diseases AU - Chase, Amanda J AU - Medina, Freddy A AU - Munoz-Jordan, Jorge L AD - Department of Biological and Environmental Sciences, Georgia College and State University, Milledgeville, ckq2@cdc.gov Y1 - 2011/06/15/ PY - 2011 DA - 2011 Jun 15 SP - 1763 EP - 1774 PB - Oxford University Press, Oxford Journals, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 203 IS - 12 SN - 0022-1899, 0022-1899 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Virology & AIDS Abstracts; Immunology Abstracts; Health & Safety Science Abstracts KW - Dengue virus KW - Human diseases KW - Serotypes KW - Genotypes KW - Hosts KW - Infection KW - Public health KW - Gene expression KW - Dendritic cells KW - CD4 antigen KW - Endemic species KW - Infectious diseases KW - Dengue KW - Lymphocytes T KW - Monocytes KW - Antigen-presenting cells KW - beta -Interferon KW - Polarization KW - Strains KW - Effector cells KW - Interferon KW - Viral diseases KW - alpha -Interferon KW - Cell proliferation KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - Q1 08484:Species interactions: parasites and diseases KW - F 06910:Microorganisms & Parasites KW - Q5 08524:Public health, medicines, dangerous organisms KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1642622829?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Impairment+of+CD4+super%28%2B%29+T+Cell+Polarization+by+Dengue+Virus-Infected+Dendritic+Cells&rft.au=Chase%2C+Amanda+J%3BMedina%2C+Freddy+A%3BMunoz-Jordan%2C+Jorge+L&rft.aulast=Chase&rft.aufirst=Amanda&rft.date=2011-06-15&rft.volume=203&rft.issue=12&rft.spage=1763&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1093%2Finfdis%2Fjir197 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-01-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Gene expression; Endemic species; Human diseases; Infectious diseases; Viral diseases; Hosts; Strains; Polarization; Public health; beta -Interferon; Serotypes; Genotypes; Infection; Effector cells; Interferon; Dendritic cells; CD4 antigen; Dengue; alpha -Interferon; Lymphocytes T; Antigen-presenting cells; Monocytes; Cell proliferation; Dengue virus DO - http://dx.doi.org/10.1093/infdis/jir197 ER - TY - JOUR T1 - William Daniel Sudia AN - 893318810; 15156925 JF - Journal of the American Mosquito Control Association AU - Comer, James A AU - Calisher, Charles H AD - Viral Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, GA Y1 - 2011/06// PY - 2011 DA - Jun 2011 SP - 177 EP - 179 PB - American Mosquito Control Association, P.O. Box 586 Milltown, NJ 08850-0586 United States VL - 27 IS - 2 SN - 8756-971X, 8756-971X KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources KW - Pest control KW - Aquatic insects KW - Q1 08485:Species interactions: pests and control KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/893318810?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+American+Mosquito+Control+Association&rft.atitle=William+Daniel+Sudia&rft.au=Comer%2C+James+A%3BCalisher%2C+Charles+H&rft.aulast=Comer&rft.aufirst=James&rft.date=2011-06-01&rft.volume=27&rft.issue=2&rft.spage=177&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+American+Mosquito+Control+Association&rft.issn=8756971X&rft_id=info:doi/10.2987%2F8756-971X-27.2.177 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-09-01 N1 - Last updated - 2015-02-12 N1 - SubjectsTermNotLitGenreText - Pest control; Aquatic insects DO - http://dx.doi.org/10.2987/8756-971X-27.2.177 ER - TY - JOUR T1 - A framework for evaluating OSH program effectiveness using leading and trailing metrics AN - 888113856; 15592235 AB - The goals of this pilot study were to create leading metrics (company self-assessment ratings) and trailing metrics (past loss data) that could be used to evaluate the effectiveness of OSH program elements that range from primary to tertiary prevention. The main hypothesis was that the new metrics would be explanatory variables for three standard future workers compensation (WC) outcomes in 2003 (rates of total cases, lost time cases, and costs) and that the framework for evaluating OSH programs could be justifiably expanded. For leading metrics, surveys were developed to allow respondents to assess OSH exposures and program prevention elements (management leadership/ commitment, employee participation, hazard identification, hazard control, medical management, training, and program evaluation). After pre-testing, surveys were sent to companies covered by the same WC insurer in early 2003. A total of 33 completed surveys were used for final analysis. A series of trailing metrics were developed from 1999-2001 WC data for the surveyed companies. Data were analyzed using a method where each main 2003 WC outcome was dichotomized into high and low loss groups based on the median value of the variable. The mean and standard deviations of survey questions and 1999-2001 WC variables were compared between the dichotomized groups. Hypothesis testing was performed using F-test with a significance level 0.10. Results/Discussion: Companies that exhibited higher musculoskeletal disorder (MSD) WC case rates from 1999-2001 had higher total WC case rates in 2003. Higher levels of several self-reported OSH program elements (tracking progress in controlling workplace safety hazards, identifying ergonomic hazards, using health promotion programs) were associated with lower rates of WC lost time cases in 2003. Higher reported exposures to noise and projectiles were also associated with higher rates of WC cases and costs in 2003. Impact on Industry: This research adds to a growing body of preliminary evidence that valid leading and trailing metrics can be developed to evaluate OSH effectiveness. Both the rating of OSH efforts and the regular trending of past loss outcomes are likely useful in developing data-driven improvement plans that are reactive to past exposures and proactive in identifying system deficiencies that drive future losses. JF - Journal of Safety Research AU - Wurzelbacher, Steve AU - Jin, Yan Y1 - 2011/06// PY - 2011 DA - Jun 2011 SP - 199 EP - 207 PB - Elsevier B.V., P.O. Box 800 Kidlington Oxford OX5 1DX United Kingdom VL - 42 IS - 3 SN - 0022-4375, 0022-4375 KW - Health & Safety Science Abstracts KW - workers' compensation KW - Training KW - Noise levels KW - musculoskeletal system KW - prevention KW - health promotion KW - Ergonomics KW - Occupational health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/888113856?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Safety+Research&rft.atitle=A+framework+for+evaluating+OSH+program+effectiveness+using+leading+and+trailing+metrics&rft.au=Wurzelbacher%2C+Steve%3BJin%2C+Yan&rft.aulast=Wurzelbacher&rft.aufirst=Steve&rft.date=2011-06-01&rft.volume=42&rft.issue=3&rft.spage=199&rft.isbn=&rft.btitle=&rft.title=Journal+of+Safety+Research&rft.issn=00224375&rft_id=info:doi/10.1016%2Fj.jsr.2011.04.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-09-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - workers' compensation; Training; Noise levels; prevention; health promotion; Ergonomics; musculoskeletal system; Occupational health DO - http://dx.doi.org/10.1016/j.jsr.2011.04.001 ER - TY - JOUR T1 - Barriers to Managing Diabetes During Pregnancy: The Perceptions of Health Care Practitioners AN - 879477147; 14887454 AB - Abstract: Background: Uncontrolled pregestational diabetes in pregnancy is associated with an increased risk for a major birth defect and additional adverse pregnancy outcomes. The study objective was to investigate the concerns of health care practitioners who care for women with a history of diabetes during pregnancy and their perceptions of attitudes and barriers to achieving good glycemic control. Methods: Focus groups were conducted with physicians, midlevel practitioners, and certified diabetes educators in Atlanta, Georgia. Practitioners were eligible if they actively practiced, primarily in outpatient facilities in Atlanta, and were neither students nor interns. Six focus groups, two of each practitioner type, were conducted. Results: Practitioners stated that few of their patients planned their pregnancies. Practitioners perceived that pregnant women were concerned primarily about their babies and might not be aware of complications with their personal health. Their perceptions of the greatest barriers to glycemic control for women involved lack of knowledge, lack of access, and attitude. Conclusions: Educating women with diabetes about the importance of using effective birth control until they have achieved good glycemic control can help reduce the risk for adverse pregnancy outcomes. Motivators and barriers for a woman with diabetes to achieve glycemic control before, during, and after pregnancy should be considered when developing approaches to improve outcomes. Helping practitioners know what and how to address the needs of childbearing women with or at risk for diabetes can be beneficial. Additional efforts to increase women's knowledge about diabetes and pregnancy and to develop effective strategies to encourage women's achievement and maintenance of glycemic control before, during, and after pregnancy are needed. (BIRTH 38:2 June 2011) JF - Birth AU - Mersereau, Patricia AU - Williams, Jennifer AU - Collier, Sarah A AU - Mulholland, Celene AU - Turay, Khadija AU - Prue, Christine AD - Patricia Mersereau is a Health Communication Specialist with SciMetrika, L.L.C., for the U.S. Centers for Disease Control and Prevention (CDC), National Center on Birth Defects and Developmental Disabilities (NCBDDD); Jennifer Williams is a Commander in the U.S. Public Health Service and a Nurse Epidemiologist at CDC, NCBDDD; Sarah Collier is an Analytic Epidemiologist with Atlanta Research and Education Foundation for CDC, National Center for Emerging and Zoonotic Infectious Diseases (NCZVED); Celine Mulholland is a Medical Student at the University of California, Los Angeles, California; Khadija Turay is a Doctoral Candidate at the University of North Carolina at Chapel Hill, North Carolina; Christine Prue is Associate Director for Behavioral Science (Acting), CDC, NCZVED, Atlanta, Georgia, United States of America. Y1 - 2011/06// PY - 2011 DA - Jun 2011 SP - 142 EP - 149 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 USA VL - 38 IS - 2 SN - 0730-7659, 0730-7659 KW - Risk Abstracts KW - Congenital defects KW - Health care KW - Maintenance KW - Perception KW - Pregnancy KW - attitudes KW - complications KW - diabetes mellitus KW - risk reduction KW - USA, Georgia, Atlanta KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/879477147?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Birth&rft.atitle=Barriers+to+Managing+Diabetes+During+Pregnancy%3A+The+Perceptions+of+Health+Care+Practitioners&rft.au=Mersereau%2C+Patricia%3BWilliams%2C+Jennifer%3BCollier%2C+Sarah+A%3BMulholland%2C+Celene%3BTuray%2C+Khadija%3BPrue%2C+Christine&rft.aulast=Mersereau&rft.aufirst=Patricia&rft.date=2011-06-01&rft.volume=38&rft.issue=2&rft.spage=142&rft.isbn=&rft.btitle=&rft.title=Birth&rft.issn=07307659&rft_id=info:doi/10.1111%2Fj.1523-536X.2010.00464.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-07-01 N1 - Document feature - figure 0 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - risk reduction; diabetes mellitus; complications; Health care; Perception; Congenital defects; Maintenance; attitudes; Pregnancy; USA, Georgia, Atlanta DO - http://dx.doi.org/10.1111/j.1523-536X.2010.00464.x ER - TY - JOUR T1 - UTILIZATION OF HIV VOLUNTARY COUNSELING AND TESTING IN VIETNAM: AN EVALUATION OF 5 YEARS OF ROUTINE PROGRAM DATA FOR NATIONAL RESPONSE AN - 876248766; 15112067 AB - This study evaluated the utilization of HIV voluntary counseling-and-testing (VCT) services targeting high-risk populations in Vietnam in order to inform decisions on program improvement and expansion. A total of 158,888 records collected from 55 VCT sites supported by the U.S. Centers for Disease Control and Prevention's Global AIDS Program in the period of 2002 to 2007 were used to analyze sociodemographic characteristics, risk exposures, seropositivity, test refusal, and failure to return for test results among VCT clients. High-risk exposures, such as injection drug use, commercial sex work, homosexual contacts or heterosexual contacts with high-risk sex partners, were reported in 126,815 (81%) records. Among high-risk clients, any condom use in the past month ranged from 34% to 71%. During the study period, 19% of the VCT encounters resulted in a positive HIV test; of those persons tested, 23% of men and 13% of women were HIV-positive. High HIV positivity rates were associated with injection drug use, being ill/recommended by health care provider, and having an HIV-infected sex partner. Of all records, 6.1% documented refusal of HIV testing. Failure to return for results was reported in 3.5% of records for clients who were tested. Previously testing positive was the strongest predictor of test refusal, and being referred by peer educators was associated with failure to return for results. The VCT program in Vietnam successfully targeted high-risk populations, and clients had high return rates using a standard testing strategy. Interventions to increase consistent condom use and promote access to prevention services among sex partners of high-risk individuals should be implemented and evaluated. JF - AIDS Education and Prevention AU - Hong, NTT AU - Wolfe, MI AU - Dat, T T AU - McFarland, DA AU - Lamb, M L AU - Thang, N T AU - Thai, H N AU - Del Rio, C AD - US Embassy-Hanoi, DHHS/CDC, 7 Lang Ha St., Dong Da, Hanoi 1000, Vietnam, nguyenht@vn.cdc.gov Y1 - 2011/06// PY - 2011 DA - Jun 2011 SP - 30 EP - 48 VL - 23 SN - 0899-9546, 0899-9546 KW - Risk Abstracts; Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Acquired immune deficiency syndrome KW - Data processing KW - homosexuality KW - Disease control KW - Drug abuse KW - Vietnam KW - Condoms KW - prostitution KW - USA KW - Education KW - Health care KW - Human immunodeficiency virus KW - Risk factors KW - prevention KW - condoms KW - Risk groups KW - Drugs KW - Sex KW - V 22360:AIDS and HIV KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/876248766?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+Education+and+Prevention&rft.atitle=UTILIZATION+OF+HIV+VOLUNTARY+COUNSELING+AND+TESTING+IN+VIETNAM%3A+AN+EVALUATION+OF+5+YEARS+OF+ROUTINE+PROGRAM+DATA+FOR+NATIONAL+RESPONSE&rft.au=Hong%2C+NTT%3BWolfe%2C+MI%3BDat%2C+T+T%3BMcFarland%2C+DA%3BLamb%2C+M+L%3BThang%2C+N+T%3BThai%2C+H+N%3BDel+Rio%2C+C&rft.aulast=Hong&rft.aufirst=NTT&rft.date=2011-06-01&rft.volume=23&rft.issue=&rft.spage=30&rft.isbn=&rft.btitle=&rft.title=AIDS+Education+and+Prevention&rft.issn=08999546&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-07-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Condoms; Acquired immune deficiency syndrome; Data processing; Risk factors; Disease control; Risk groups; Drugs; Sex; prostitution; Education; Health care; Human immunodeficiency virus; homosexuality; condoms; prevention; Drug abuse; USA; Vietnam ER - TY - JOUR T1 - General Principles of Medical Surveillance Implications for Workers Potentially Exposed to Nanomaterials AN - 876243272; 15112460 AB - Objective: As potential occupational exposure to nanomaterials becomes more prevalent, it is important that the principles of medical surveillance be considered for workers in the nanotechnology industry. Methods: The principles of medical surveillance are reviewed to further the discussion of occupational health surveillance for workers exposed to nanomaterials. Results: Because of the rapid evolution of nanotechnology, information may not be available to make a well-informed determination of all factors needed to evaluate risk of health effects from occupational exposure to nanomaterials. Conclusion: Every workplace dealing with engineered nanomaterials should conduct hazard and exposure assessments as part of an overall surveillance needs assessment for nanotechnology workers. In workplaces where risk is felt to be present, or at least cannot be ruled out, initiation of medical surveillance is prudent to protect workers' health. JF - Journal of Occupational and Environmental Medicine AU - Trout, D B AD - DSHEFS, NIOSH, R-12, 4676 Columbia Parkway, Cincinnati, OH 45226, USA, dtrout@cdc.gov Y1 - 2011/06// PY - 2011 DA - Jun 2011 SP - S22 EP - S24 VL - 53 SN - 1076-2752, 1076-2752 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Reviews KW - Occupational exposure KW - nanotechnology KW - Occupational health KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/876243272?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=General+Principles+of+Medical+Surveillance+Implications+for+Workers+Potentially+Exposed+to+Nanomaterials&rft.au=Trout%2C+D+B&rft.aulast=Trout&rft.aufirst=D&rft.date=2011-06-01&rft.volume=53&rft.issue=&rft.spage=S22&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e31821b1e45 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-07-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Reviews; Occupational exposure; Occupational health; nanotechnology DO - http://dx.doi.org/10.1097/JOM.0b013e31821b1e45 ER - TY - JOUR T1 - Overview of Current Toxicological Knowledge of Engineered Nanoparticles AN - 876243251; 15112458 AB - Objective: Nanotechnology is the manipulation of matter on a near-atomic scale to produce nanoparticles with unique properties, allowing new commercial applications. Since nanoparticles exhibit unique physicochemical properties, they are likely to exhibit biological activity significantly different from fine-sized particles of the same chemical composition. Therefore, evaluation of the biological effects of nanoparticles is critical. Methods: The article lists the major objectives of nanotoxicology and briefly reviews the literature concerning biological responses to pulmonary exposure. Results: Interactions of nanoparticles with biological systems depend on particle size, shape, oxidant generation, surface functionalization, and rate of dissolution. Pulmonary, cardiovascular, and central nervous system responses to pulmonary exposure to nanotitanium dioxide and carbon nanotubes are described. Conclusions: Significant biological responses occur in animal models after pulmonary exposure to certain nanoparticles. Control of exposure appears prudent to protect worker health. Clinical Significance: Nanotechnology is synthesizing a wide range of nanoparticles, which exhibit unique physicochemical properties. These unique properties make unique biological activity likely. If certain nanoparticles induce adverse effects in vitro or in animal models, then occupational health surveillance and exposure control may be prudent steps in the protection of worker health. JF - Journal of Occupational and Environmental Medicine AU - Castranova, V AD - NIOSH, 1095 Willowdale Road, Morgantown, WV 26505, USA, vic1@cdc.gov Y1 - 2011/06// PY - 2011 DA - Jun 2011 SP - S14 EP - S17 VL - 53 SN - 1076-2752, 1076-2752 KW - Toxicology Abstracts; Pollution Abstracts; Health & Safety Science Abstracts KW - Particle size KW - Central nervous system KW - Physicochemical properties KW - Animal models KW - Particulates KW - Carbon KW - Lung KW - Reviews KW - Dissolution KW - nanotubes KW - nanoparticles KW - Oxidants KW - Side effects KW - Occupational exposure KW - nanotechnology KW - H 1000:Occupational Safety and Health KW - P 6000:TOXICOLOGY AND HEALTH KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/876243251?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Overview+of+Current+Toxicological+Knowledge+of+Engineered+Nanoparticles&rft.au=Castranova%2C+V&rft.aulast=Castranova&rft.aufirst=V&rft.date=2011-06-01&rft.volume=53&rft.issue=&rft.spage=S14&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e31821b1e5a LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-07-01 N1 - Last updated - 2013-06-14 N1 - SubjectsTermNotLitGenreText - Central nervous system; Physicochemical properties; Animal models; Carbon; Lung; Reviews; nanotubes; Dissolution; nanoparticles; Occupational exposure; Side effects; Oxidants; nanotechnology; Particle size; Particulates DO - http://dx.doi.org/10.1097/JOM.0b013e31821b1e5a ER - TY - JOUR T1 - Epidemiology of HIV among Asians and Pacific Islanders in the United States, 2001-2008 AN - 876225390; 14877143 AB - Background: Recent analyses have shown increases in combined annual HIV diagnosis rates for Asians and Pacific Islanders (API). Methods: Using surveillance data from 33 states and 4 dependent areas we investigated the epidemiology of HIV among API during 2001-2008. Results: HIV diagnoses for API during 2001-2008 were predominantly among persons age 30-39 years (40%) and males (78%). The primary risk factor for males was sexual contact with males (78%) and for females, heterosexual contact (86%). API were the only racial/ethnic groups with a statistically significant estimated annual percentage increase (4.4%) in HIV diagnoses over the time period. Thirty-seven percent of HIV diagnoses among API progressed to AIDS in <12 months, with significantly greater likelihood among those 30 years and older. Survival was lower among API with AIDS diagnosis after 49 years of age, and was higher among persons with AIDS whose primary risk factor for infection was heterosexual contact. Conclusions: In contrast to other racial/ethnic groups, API were the only groups to show a significant increase in HIV diagnoses. A clearer understanding of the reasons for this trend is needed, so that appropriate interventions can be selected and adapted to prevent increased HIV prevalence among API in the U.S. JF - Journal of the International Association of Physicians in AIDS Care (JIAPAC) AU - Adih, William K AU - Campsmith, Michael AU - Williams, Cheryl L AU - Hardnett, Felicia P AU - Hughes, Denise AD - Division of HIV/AIDS Prevention-Surveillance and Epidemiology, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA, wadih@cdc.gov Y1 - 2011/06// PY - 2011 DA - Jun 2011 SP - 150 EP - 159 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU UK VL - 10 IS - 3 SN - 1545-1097, 1545-1097 KW - Virology & AIDS Abstracts; Risk Abstracts KW - Acquired immune deficiency syndrome KW - Age KW - Data processing KW - Statistical analysis KW - Survival KW - Infection KW - USA KW - Epidemiology KW - Human immunodeficiency virus KW - intervention KW - Risk factors KW - I, Pacific KW - infection KW - survival KW - Ethnic groups KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/876225390?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+International+Association+of+Physicians+in+AIDS+Care+%28JIAPAC%29&rft.atitle=Epidemiology+of+HIV+among+Asians+and+Pacific+Islanders+in+the+United+States%2C+2001-2008&rft.au=Adih%2C+William+K%3BCampsmith%2C+Michael%3BWilliams%2C+Cheryl+L%3BHardnett%2C+Felicia+P%3BHughes%2C+Denise&rft.aulast=Adih&rft.aufirst=William&rft.date=2011-06-01&rft.volume=10&rft.issue=3&rft.spage=150&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+International+Association+of+Physicians+in+AIDS+Care+%28JIAPAC%29&rft.issn=15451097&rft_id=info:doi/10.1177%2F1545109711399805 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-07-01 N1 - Number of references - 52 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Age; Acquired immune deficiency syndrome; Data processing; Epidemiology; Risk factors; Statistical analysis; Survival; Infection; Ethnic groups; Human immunodeficiency virus; intervention; infection; survival; USA; I, Pacific DO - http://dx.doi.org/10.1177/1545109711399805 ER - TY - JOUR T1 - School-Based Health Center Access, Reproductive Health Care, and Contraceptive Use Among Sexually Experienced High School Students AN - 874197355; 14979101 AB - The current analyses compared receipt of reproductive health care, contraceptive use, and screening for sexually transmitted diseases (STD) among adolescents who are sexually experienced, with or without access to a school clinic. Methods: A total of 12 urban California high schools, selected from areas with high teen pregnancy and STD rates, half with school-based health centers (SBHCs), participated in an intervention study designed to improve sexual health among adolescents. Of the participating students, 44% indicated that they had ever had intercourse and were included in these analyses. Results: Access to an SBHC did not influence receipt of reproductive health care for either males or females and did not influence contraceptive use, either hormonal or condoms, for males. For females, however, those with access to an SBHC had increased odds of having received pregnancy or disease prevention care (adjusted odds ratio [AOR] = 1.45, 95% confidence interval [CI] = 1.16-1.80), having used hormonal contraceptives at last sex (AOR = 1.68, 95% CI = 1.24-2.28), and were more likely to have ever been screened for an STD (AOR = 1.85, 95% CI = 1.43-2.40). Also among female students, those with access to an SBHC were more likely to have used emergency contraception at last sex (AOR = 2.1, 95% CI = 1.08-4.22). Conclusion: Although access to an on-site clinic does not seem to lead to increases in all types of reproductive care in the population as a whole, sexually active females are more likely to have received more specific care and to have used hormonal contraceptives if their school has an SBHC. JF - Journal of Adolescent Health AU - Ethier, Kathleen A AU - Dittus, Patricia J AU - DeRosa, Christine J AU - Chung, Emily Q AU - Martinez, Esteban AU - Kerndt, Peter R AD - Centers for Disease Control and Prevention, Atlanta, Georgia, kbe0@cdc.gov Y1 - 2011/06// PY - 2011 DA - Jun 2011 SP - 562 EP - 565 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 48 IS - 6 SN - 1054-139X, 1054-139X KW - Health & Safety Science Abstracts KW - contraceptives KW - Pregnancy KW - schools KW - intervention KW - condoms KW - prevention KW - Reproduction KW - USA, California KW - sexually transmitted diseases KW - Adolescents KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/874197355?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Adolescent+Health&rft.atitle=School-Based+Health+Center+Access%2C+Reproductive+Health+Care%2C+and+Contraceptive+Use+Among+Sexually+Experienced+High+School+Students&rft.au=Ethier%2C+Kathleen+A%3BDittus%2C+Patricia+J%3BDeRosa%2C+Christine+J%3BChung%2C+Emily+Q%3BMartinez%2C+Esteban%3BKerndt%2C+Peter+R&rft.aulast=Ethier&rft.aufirst=Kathleen&rft.date=2011-06-01&rft.volume=48&rft.issue=6&rft.spage=562&rft.isbn=&rft.btitle=&rft.title=Journal+of+Adolescent+Health&rft.issn=1054139X&rft_id=info:doi/10.1016%2Fj.jadohealth.2011.01.018 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-06-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - schools; intervention; prevention; condoms; Reproduction; Adolescents; sexually transmitted diseases; Pregnancy; contraceptives; USA, California DO - http://dx.doi.org/10.1016/j.jadohealth.2011.01.018 ER - TY - JOUR T1 - Evaluation of pot-chlorination of wells during a cholera outbreak, Bissau, Guinea-Bissau, 2008 AN - 874194032; 14997943 AB - We evaluated the ability of UNICEF-designed pot-chlorinators to achieve recommended free residual chlorine (FRC) levels in well water in Bissau, Guinea-Bissau, during a cholera outbreak. Thirty wells were randomly selected from six neighbourhoods. Pot-chlorinators - perforated plastic bottles filled with gravel, sand and calcium hypochlorite granules - were placed in each well. FRC was measured before and 24, 48 and 72 h after placement and compared with World Health Organization (WHO)-recommended levels of 1 mg L[super]-1 for well water during cholera outbreaks and 0.2-5 mg L[super]-1 in non-outbreak settings. Presence of well covers, distance from wells to latrines, and rainfall were noted. Complete post-chlorination data were collected from 26 wells. At baseline, no wells had FRC 0.09 mg L[super]-1. At 24, 48 and 72 h post-chlorination, 4 (15%), 1 (4%) and 0 wells had FRC 1 mg L[super]-1 and 16 (62%), 4 (15%) and 1 (4%) wells had FRC between 0.2 and 5 mg L[super]-1, respectively. Several families reported discontinuing household water chlorination after wells were treated with pot-chlorinators. Pot-chlorinators failed to achieve WHO-recommended FRC levels in well water during a cholera outbreak, and conveyed a false sense of security to local residents. Pot-chlorination should be discouraged and alternative approaches to well-water disinfection promoted. JF - Journal of Water and Health AU - Cavallaro, Elizabeth C AU - Harris, Julie R AU - Da Goia, Mauricio Serafim AU - Barrado, Jean Carlos dos Santos AU - Da Nobrega, Aglaer Alves AU - Junior, Inacio Carvalho de Alvarenga AU - Silva, Augusto Paulo AU - Sobel, Jeremy AU - Mintz, Eric AD - Mailstop C-25, Epidemic Intelligence Service Officer assigned to the Global WASH Epidemiology Team, Waterborne Diseases Prevention Branch (WDPB), Division of Foodborne, Bacterial, and Mycotic Diseases (DBFMD), National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA, ejc0@cdc.gov Y1 - 2011/06/01/ PY - 2011 DA - 2011 Jun 01 SP - 394 EP - 402 PB - IWA Publishing, Alliance House London SW1H 0QS UK VL - 9 IS - 2 SN - 1477-8920, 1477-8920 KW - ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Microbiology Abstracts B: Bacteriology; Environment Abstracts; Water Resources Abstracts; Aqualine Abstracts KW - cholera KW - pot-chlorinators KW - Vibrio cholerae KW - well chlorination KW - Granules KW - calcium hypochlorite KW - Disinfection KW - Calcium KW - Organizations KW - Rainfall KW - Chlorine KW - security KW - Well Water KW - Evaluation KW - households KW - Water treatment KW - Sand KW - Cholera KW - Plastics KW - Residual Chlorine KW - Gravel KW - Data processing KW - Pathogenic bacteria KW - Bacterial diseases KW - outbreaks KW - Guinea-Bissau KW - Water wells KW - Chlorination KW - AQ 00001:Water Resources and Supplies KW - Q5 08503:Characteristics, behavior and fate KW - Q1 08563:Fishing gear and methods KW - J 02400:Human Diseases KW - SW 6010:Structures KW - ENA 19:Water Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/874194032?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Water+and+Health&rft.atitle=Evaluation+of+pot-chlorination+of+wells+during+a+cholera+outbreak%2C+Bissau%2C+Guinea-Bissau%2C+2008&rft.au=Cavallaro%2C+Elizabeth+C%3BHarris%2C+Julie+R%3BDa+Goia%2C+Mauricio+Serafim%3BBarrado%2C+Jean+Carlos+dos+Santos%3BDa+Nobrega%2C+Aglaer+Alves%3BJunior%2C+Inacio+Carvalho+de+Alvarenga%3BSilva%2C+Augusto+Paulo%3BSobel%2C+Jeremy%3BMintz%2C+Eric&rft.aulast=Cavallaro&rft.aufirst=Elizabeth&rft.date=2011-06-01&rft.volume=9&rft.issue=2&rft.spage=394&rft.isbn=&rft.btitle=&rft.title=Journal+of+Water+and+Health&rft.issn=14778920&rft_id=info:doi/10.2166%2Fwh.2011.122 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-06-01 N1 - Last updated - 2016-03-30 N1 - SubjectsTermNotLitGenreText - Disinfection; Calcium; Organizations; Pathogenic bacteria; Bacterial diseases; Chlorination; Well Water; Granules; calcium hypochlorite; Data processing; Sand; Rainfall; Chlorine; Cholera; Plastics; households; Water treatment; Water wells; security; outbreaks; Evaluation; Gravel; Residual Chlorine; Guinea-Bissau DO - http://dx.doi.org/10.2166/wh.2011.122 ER - TY - JOUR T1 - Emergency Department Visits for Overdoses of Acetaminophen-Containing Products AN - 874182474; 14979066 AB - Limited national data on the circumstances of acetaminophen overdoses have hindered identification and implementation of prevention strategies To estimate the frequency of and characterize risks for emergency department visits for acetaminophen overdoses that were not related to abuse in the U.S. Methods: Data were collected from two components of the National Electronic Injury Surveillance System from January 1, 2006, through December 31, 2007, and analyzed from 2009 to 2010 to estimate the annual number of emergency department visits for non-abuse-related acetaminophen overdose by patient demographics, treatments, and type and amount of acetaminophen-containing product ingested. Results: There were an estimated 78,414 emergency department visits (95% CI=63655, 93172) annually for non-abuse-related overdoses of acetaminophen-containing products. Most emergency department visits for acetaminophen overdose were for self-directed violence (69.8%, 95% CI=66.4%, 73.2%), with the highest rate among patients aged 15-24 years (46.4 per 100,000 individuals per year). Unsupervised ingestions by children aged <6 years accounted for 13.4% (95% CI=11.0%, 15.9%) of visits for acetaminophen overdoses (42.5 per 100,000 individuals per year). Therapeutic misadventures accounted for 16.7% (95% CI=14.0%, 19.5%) of visits and most involved overuse for medicinal effects (56.1%, 95% CI=50.6%, 61.6%) rather than use of multiple acetaminophen-containing products or dose confusion. Conclusions: Non-abuse-related overdoses of acetaminophen products lead to many emergency department visits each year, particularly emergency department visits for self-directed violence. Acetaminophen overdose prevention efforts will likely need to be multidimensional. JF - American Journal of Preventive Medicine AU - Budnitz, Daniel S AU - Lovegrove, Maribeth C AU - Crosby, Alexander E AD - Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, CDC, Atlanta, Georgia, dbudnitz@cdc.gov Y1 - 2011/06// PY - 2011 DA - Jun 2011 SP - 585 EP - 592 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 40 IS - 6 SN - 0749-3797, 0749-3797 KW - Risk Abstracts KW - demography KW - Injuries KW - Ingestion KW - Children KW - Violence KW - USA KW - prevention KW - overdose KW - emergency medical services KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/874182474?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Emergency+Department+Visits+for+Overdoses+of+Acetaminophen-Containing+Products&rft.au=Budnitz%2C+Daniel+S%3BLovegrove%2C+Maribeth+C%3BCrosby%2C+Alexander+E&rft.aulast=Budnitz&rft.aufirst=Daniel&rft.date=2011-06-01&rft.volume=40&rft.issue=6&rft.spage=585&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2011.02.026 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-06-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - demography; Injuries; prevention; overdose; Children; Ingestion; Violence; emergency medical services; USA DO - http://dx.doi.org/10.1016/j.amepre.2011.02.026 ER - TY - JOUR T1 - Preventing disasters: public health vulnerability reduction as a sustainable adaptation to climate change. AN - 873122391; 21402799 AB - Global warming could increase the number and severity of extreme weather events. These events are often known to result in public health disasters, but we can lessen the effects of these disasters. By addressing the factors that cause changes in climate, we can mitigate the effects of climate change. By addressing the factors that make society vulnerable to the effects of climate, we can adapt to climate change. To adapt to climate change, a comprehensive approach to disaster risk reduction has been proposed. By reducing human vulnerability to disasters, we can lessen--and at times even prevent--their impact. Human vulnerability is a complex phenomenon that comprises social, economic, health, and cultural factors. Because public health is uniquely placed at the community level, it has the opportunity to lessen human vulnerability to climate-related disasters. At the national and international level, a supportive policy environment can enable local adaptation to disaster events. The purpose of this article is to introduce the basic concept of disaster risk reduction so that it can be applied to preventing and mitigating the negative effects of climate change and to examine the role of community-focused public health as a means for lessening human vulnerability and, as a result, the overall risk of climate-related disasters. JF - Disaster medicine and public health preparedness AU - Keim, Mark E AD - National Center for Environmental Health Agency for Toxic Substances and Disease Registry, Centers for Disease Control and Prevention, Atlanta, GA 30341-3724, USA. mjk9@cdc.gov Y1 - 2011/06// PY - 2011 DA - June 2011 SP - 140 EP - 148 VL - 5 IS - 2 KW - Index Medicus KW - Poverty KW - Humans KW - Health Status Disparities KW - Capacity Building KW - Health Policy KW - Risk Assessment KW - Models, Theoretical KW - Risk Reduction Behavior KW - Public Health Practice KW - Climate Change KW - Program Evaluation KW - Disaster Planning -- methods KW - Disasters -- prevention & control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/873122391?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Disaster+medicine+and+public+health+preparedness&rft.atitle=Preventing+disasters%3A+public+health+vulnerability+reduction+as+a+sustainable+adaptation+to+climate+change.&rft.au=Keim%2C+Mark+E&rft.aulast=Keim&rft.aufirst=Mark&rft.date=2011-06-01&rft.volume=5&rft.issue=2&rft.spage=140&rft.isbn=&rft.btitle=&rft.title=Disaster+medicine+and+public+health+preparedness&rft.issn=1938-744X&rft_id=info:doi/10.1001%2Fdmp.2011.30 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-08-29 N1 - Date created - 2011-06-20 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1001/dmp.2011.30 ER - TY - JOUR T1 - Barriers to early uptake of tetanus, diphtheria and acellular pertussis vaccine (Tdap) among adults - United States, 2005-2007 AN - 874182169; 14977543 AB - The tetanus, diphtheria and acellular pertussis vaccine (Tdap) was recommended by the Advisory Committee on Immunization Practices (ACIP) for U.S. adults in 2005. Our objective was to identify barriers to early uptake of Tdap among adult populations. Methods: The 2007 National Immunization Survey (NIS)-Adult was a telephone survey sponsored by the Centers for Disease Control and Prevention (CDC). Immunization information was collected for persons aged >=18 years on all ACIP-recommended vaccines. A weighted analysis accounted for the complex survey design and non-response. Results: Overall, 3.6% of adults aged 18-64 years reported receipt of a Tdap vaccination. Of unvaccinated respondents, 18.8% had heard of Tdap, of which 9.4% reported that a healthcare provider had recommended it. A low perceived risk of contracting pertussis was the single most common reason for either not vaccinating with Tdap or being unwilling to do so (44.7%). Most unvaccinated respondents (81.8%) indicated a willingness to receive Tdap if it was recommended by a provider. Conclusions: During the first two years of availability, Tdap uptake was likely inhibited by a low collective awareness of Tdap and a low perceived risk of contracting pertussis among U.S. adults, as well as a paucity of provider-to-patient vaccination recommendations. Significant potential exists for improved coverage, as many adults were receptive to vaccination. JF - Vaccine AU - Miller, Brady L AU - Kretsinger, Katrina AU - Euler, Gary L AU - Lu, Peng-Jun AU - Ahmed, Faruque AD - Immunization Services Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA, ion2@cdc.gov Y1 - 2011/05/17/ PY - 2011 DA - 2011 May 17 SP - 3850 EP - 3856 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 29 IS - 22 SN - 0264-410X, 0264-410X KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Pertussis KW - Risk factors KW - Disease control KW - Vaccines KW - Diphtheria KW - Tetanus KW - F 06905:Vaccines KW - J 02350:Immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/874182169?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Barriers+to+early+uptake+of+tetanus%2C+diphtheria+and+acellular+pertussis+vaccine+%28Tdap%29+among+adults+-+United+States%2C+2005-2007&rft.au=Miller%2C+Brady+L%3BKretsinger%2C+Katrina%3BEuler%2C+Gary+L%3BLu%2C+Peng-Jun%3BAhmed%2C+Faruque&rft.aulast=Miller&rft.aufirst=Brady&rft.date=2011-05-17&rft.volume=29&rft.issue=22&rft.spage=3850&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/10.1016%2Fj.vaccine.2011.03.058 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-06-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Pertussis; Risk factors; Disease control; Diphtheria; Vaccines; Tetanus DO - http://dx.doi.org/10.1016/j.vaccine.2011.03.058 ER - TY - JOUR T1 - 6-month versus 36-month isoniazid preventive treatment for tuberculosis in adults with HIV infection in Botswana: a randomised, double-blind, placebo-controlled trial AN - 907167352; 14978973 AB - In accordance with WHO guidelines, people with HIV infection in Botswana receive daily isoniazid preventive therapy against tuberculosis without obtaining a tuberculin skin test, but duration of prophylaxis is restricted to 6 months. We aimed to assess effectiveness of extended isoniazid therapy. Methods: In our randomised, double-blind, placebo-controlled trial we enrolled adults infected with HIV aged 18 years or older at government HIV-care clinics in Botswana. Exclusion criteria included current illness such as cough and an abnormal chest radiograph without antecedent tuberculosis or pneumonia. Eligible individuals were randomly allocated (1:1) to receive 6 months' open-label isoniazid followed by 30 months' masked placebo (control group) or 6 months' open-label isoniazid followed by 30 months' masked isoniazid (continued isoniazid group) on the basis of a computer-generated randomisation list with permuted blocks of ten at each clinic. Antiretroviral therapy was provided if participants had CD4-positive lymphocyte counts of fewer than 200 cells per [micro]L. We used Cox regression analysis and the log-rank test to compare incident tuberculosis in the groups. Cox regression models were used to estimate the effect of antiretroviral therapy. The trial is registered at ClinicalTrials.gov, number NCT00164281. Findings: Between Nov 26, 2004, and July 3, 2009, we recorded 34 (3 super(.)4%) cases of incident tuberculosis in 989 participants allocated to the control group and 20 (2 super(.)0%) in 1006 allocated to the continued isoniazid group (incidence 1 super(.)26% per year vs 0 super(.)72%; hazard ratio 0 super(.)57, 95% CI 0 super(.)33-0 super(.)99, p=0 super(.)047). Tuberculosis incidence in those individuals receiving placebo escalated approximately 200 days after completion of open-label isoniazid. Participants who were tuberculin skin test positive (ie, >=5 mm induration) at enrolment received a substantial benefit from continued isoniazid treatment (0 super(.)26, 0 super(.)09-0 super(.)80, p=0 super(.)02), whereas participants who were tuberculin skin test-negative received no significant benefit (0 super(.)75, 0 super(.)38-1 super(.)46, p=0 super(.)40). By study completion, 946 (47%) of 1995 participants had initiated antiretroviral therapy. Tuberculosis incidence was reduced by 50% in those receiving 360 days of antiretroviral therapy compared with participants receiving no antiretroviral therapy (adjusted hazard ratio 0 super(.)50, 95% CI 0 super(.)26-0 super(.)97). Severe adverse events and death were much the same in the control and continued isoniazid groups. Interpretation: In a tuberculosis-endemic setting, 36 months' isoniazid prophylaxis was more effective for prevention of tuberculosis than was 6-month prophylaxis in individuals with HIV infection, and chiefly benefited those who were tuberculin skin test positive. Funding: US Centers for Disease Control and Prevention and US Agency for International Development. JF - Lancet AU - Samandari, Taraz AU - Agizew, Tefera B AU - Nyirenda, Samba AU - Tedla, Zegabriel AU - Sibanda, Thabisa AU - Shang, Nong AU - Mosimaneotsile, Barudi AU - Motsamai, Oaitse I AU - Bozeman, Lorna AU - Davis, Margarett K AU - Talbot, Elizabeth A AU - Moeti, Themba L AU - Moffat, Howard J AU - Kilmarx, Peter H AU - Castro, Kenneth G AU - Wells, Charles D AD - Botswana-USA Partnership (BOTUSA), Gaborone and Francistown, Botswana, tts0@cdc.gov tts0@cdc.gov tts0@cdc.gov tts0@cdc.gov tts0@cdc.gov tts0@cdc.gov tts0@cdc.gov Y1 - 2011/05/13/ PY - 2011 DA - 2011 May 13 SP - 1588 EP - 1598 PB - The Lancet Ltd., 655 Ave. of the Americas New York NY 10011 USA VL - 377 IS - 9777 SN - 0140-6736, 0140-6736 KW - Microbiology Abstracts B: Bacteriology KW - CD4 antigen KW - Cell number KW - Chest KW - Cough KW - Disease control KW - Infection KW - Isoniazid KW - Pneumonia KW - Prophylaxis KW - Radiography KW - Regression analysis KW - Skin tests KW - Tuberculin KW - Tuberculosis KW - antiretroviral therapy KW - Mycobacterium KW - Human immunodeficiency virus KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/907167352?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Lancet&rft.atitle=6-month+versus+36-month+isoniazid+preventive+treatment+for+tuberculosis+in+adults+with+HIV+infection+in+Botswana%3A+a+randomised%2C+double-blind%2C+placebo-controlled+trial&rft.au=Samandari%2C+Taraz%3BAgizew%2C+Tefera+B%3BNyirenda%2C+Samba%3BTedla%2C+Zegabriel%3BSibanda%2C+Thabisa%3BShang%2C+Nong%3BMosimaneotsile%2C+Barudi%3BMotsamai%2C+Oaitse+I%3BBozeman%2C+Lorna%3BDavis%2C+Margarett+K%3BTalbot%2C+Elizabeth+A%3BMoeti%2C+Themba+L%3BMoffat%2C+Howard+J%3BKilmarx%2C+Peter+H%3BCastro%2C+Kenneth+G%3BWells%2C+Charles+D&rft.aulast=Samandari&rft.aufirst=Taraz&rft.date=2011-05-13&rft.volume=377&rft.issue=9777&rft.spage=1588&rft.isbn=&rft.btitle=&rft.title=Lancet&rft.issn=01406736&rft_id=info:doi/10.1016%2FS0140-6736%2811%2960204-3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2013-02-08 N1 - SubjectsTermNotLitGenreText - Cell number; antiretroviral therapy; Disease control; Cough; Chest; Infection; Skin tests; CD4 antigen; Prophylaxis; Regression analysis; Tuberculosis; Tuberculin; Radiography; Pneumonia; Isoniazid; Mycobacterium; Human immunodeficiency virus DO - http://dx.doi.org/10.1016/S0140-6736(11)60204-3 ER - TY - JOUR T1 - Functional Analysis of the Borrelia burgdorferi bba64 Gene Product in Murine Infection via Tick Infestation AN - 879474148; 14874733 AB - Borrelia burgdorferi, the causative agent of Lyme borreliosis, is transmitted to humans from the bite of Ixodes spp. ticks. During the borrelial tick-to-mammal life cycle, B. burgdorferi must adapt to many environmental changes by regulating several genes, including bba64. Our laboratory recently demonstrated that the bba64 gene product is necessary for mouse infectivity when B. burgdorferi is transmitted by an infected tick bite, but not via needle inoculation. In this study we investigated the phenotypic properties of a bba64 mutant strain, including 1) replication during tick engorgement, 2) migration into the nymphal salivary glands, 3) host transmission, and 4) susceptibility to the MyD88-dependent innate immune response. Results revealed that the bba64 mutant's attenuated infectivity by tick bite was not due to a growth defect inside an actively feeding nymphal tick, or failure to invade the salivary glands. These findings suggested there was either a lack of spirochete transmission to the host dermis or increased susceptibility to the host's innate immune response. Further experiments showed the bba64 mutant was not culturable from mouse skin taken at the nymphal bite site and was unable to establish infection in MyD88-deficient mice via tick infestation. Collectively, the results of this study indicate that BBA64 functions at the salivary gland-to-host delivery interface of vector transmission and is not involved in resistance to MyD88-mediated innate immunity. JF - PLoS ONE AU - Patton, Toni G AU - Dietrich, Gabrielle AU - Dolan, Marc C AU - Piesman, Joseph AU - Carroll, James A AU - Gilmore, Robert D AD - Microbiology and Pathogenesis Activity, Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado, United States of America Y1 - 2011/05/03/ PY - 2011 DA - 2011 May 03 PB - BioMed Central Ltd., Middlesex House London W1T 4LB UK VL - 6 IS - 5 KW - Entomology Abstracts; Microbiology Abstracts B: Bacteriology KW - Borrelia burgdorferi KW - Bites KW - Z 05320:Physiology, Anatomy, and Biochemistry KW - J 02350:Immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/879474148?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=PLoS+ONE&rft.atitle=Functional+Analysis+of+the+Borrelia+burgdorferi+bba64+Gene+Product+in+Murine+Infection+via+Tick+Infestation&rft.au=Patton%2C+Toni+G%3BDietrich%2C+Gabrielle%3BDolan%2C+Marc+C%3BPiesman%2C+Joseph%3BCarroll%2C+James+A%3BGilmore%2C+Robert+D&rft.aulast=Patton&rft.aufirst=Toni&rft.date=2011-05-03&rft.volume=6&rft.issue=5&rft.spage=&rft.isbn=&rft.btitle=&rft.title=PLoS+ONE&rft.issn=1932-6203&rft_id=info:doi/10.1371%2Fjournal.pone.0019536 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-07-01 N1 - Last updated - 2014-03-24 N1 - SubjectsTermNotLitGenreText - Bites; Borrelia burgdorferi DO - http://dx.doi.org/10.1371/journal.pone.0019536 ER - TY - JOUR T1 - Molecular Detection of Mutations Associated with First- and Second-Line Drug Resistance Compared with Conventional Drug Susceptibility Testing of Mycobacterium tuberculosis AN - 911158793; 16062607 AB - The emergence of multi- and extensively drug-resistant tuberculosis is a significant impediment to the control of this disease because treatment becomes more complex and costly. Reliable and timely drug susceptibility testing is critical to ensure that patients receive effective treatment and become noninfectious. Molecular methods can provide accurate and rapid drug susceptibility results. We used DNA sequencing to detect resistance to the first-line antituberculosis drugs isoniazid (INH), rifampin (RIF), pyrazinamide (PZA), and ethambutol (EMB) and the second-line drugs amikacin (AMK), capreomycin (CAP), kanamycin (KAN), ciprofloxacin (CIP), and ofloxacin (OFX). Nine loci were sequenced: rpoB (for resistance to RIF), katG and inhA (INH), pncA (PZA), embB (EMB), gyrA (CIP and OFX), and rrs, eis, and tlyA (KAN, AMK, and CAP). A total of 314 clinical Mycobacterium tuberculosis complex isolates representing a variety of antibiotic resistance patterns, genotypes, and geographical origins were analyzed. The molecular data were compared to the phenotypic data and the accuracy values were calculated. Sensitivity and specificity values for the first-line drug loci were 97.1% and 93.6% for rpoB, 85.4% and 100% for katG, 16.5% and 100% for inhA, 90.6% and 100% for katG and inhA together, 84.6% and 85.8% for pncA, and 78.6% and 93.1% for embB. The values for the second-line drugs were also calculated. The size and scope of this study, in numbers of loci and isolates examined, and the phenotypic diversity of those isolates support the use of DNA sequencing to detect drug resistance in the M. tuberculosis complex. Further, the results can be used to design diagnostic tests utilizing other mutation detection technologies. JF - Antimicrobial Agents & Chemotherapy AU - Campbell, Patricia J AU - Morlock, Glenn P AU - Sikes, David AU - Dalton, Tracy L AU - Metchock, Beverly AU - Starks, Angela M AU - Hooks, Delaina P AU - Cowan, Lauren S AU - Plikaytis, Bonnie B AU - Posey, James E AD - Mycobacteriology Laboratory Branch, Division of Tuberculosis Elimination, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, jposey@cdc.gov Y1 - 2011/05// PY - 2011 DA - May 2011 SP - 2032 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 55 IS - 5 SN - 0066-4804, 0066-4804 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Amikacin KW - Antibiotic resistance KW - Capreomycin KW - Ciprofloxacin KW - DNA sequencing KW - Data processing KW - Drug resistance KW - Genotypes KW - Geographical distribution KW - Isoniazid KW - Kanamycin KW - Mutation KW - Ofloxacin KW - Rifampin KW - RpoB protein KW - Tuberculosis KW - ethambutol KW - pyrazinamide KW - Mycobacterium tuberculosis KW - A 01340:Antibiotics & Antimicrobials KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/911158793?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Molecular+Detection+of+Mutations+Associated+with+First-+and+Second-Line+Drug+Resistance+Compared+with+Conventional+Drug+Susceptibility+Testing+of+Mycobacterium+tuberculosis&rft.au=Campbell%2C+Patricia+J%3BMorlock%2C+Glenn+P%3BSikes%2C+David%3BDalton%2C+Tracy+L%3BMetchock%2C+Beverly%3BStarks%2C+Angela+M%3BHooks%2C+Delaina+P%3BCowan%2C+Lauren+S%3BPlikaytis%2C+Bonnie+B%3BPosey%2C+James+E&rft.aulast=Campbell&rft.aufirst=Patricia&rft.date=2011-05-01&rft.volume=55&rft.issue=5&rft.spage=2032&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.01550-10 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-12-01 N1 - Number of references - 45 N1 - Last updated - 2012-08-24 N1 - SubjectsTermNotLitGenreText - Geographical distribution; Data processing; Amikacin; Drug resistance; Ofloxacin; Kanamycin; Genotypes; Rifampin; Ciprofloxacin; DNA sequencing; Capreomycin; pyrazinamide; Tuberculosis; ethambutol; Mutation; RpoB protein; Antibiotic resistance; Isoniazid; Mycobacterium tuberculosis DO - http://dx.doi.org/10.1128/AAC.01550-10 ER - TY - JOUR T1 - Emergency Department Visits for Antiviral Adverse Events During the 2009 H1N1 Influenza Pandemic AN - 908014098; 2011-146818 AB - The 2009 pandemic influenza A (H1N1) outbreak was associated with an increased use of antiviral agents and highlighted the role of population-based monitoring for related adverse drug events (ADEs). An ongoing, nationally representative emergency department-based surveillance system was used to identify and characterize ADEs during the pandemic. Active surveillance for ADEs successfully provided timely, population-based data during the pandemic. Increases in antiviral ADEs paralleled increases in prescribing. Type and severity of ADEs were similar across all seasons. Adapted from the source document. JF - Public Health Reports AU - Lovegrove, Maribeth C AU - Shehab, Nadine AU - Hales, Craig M AU - Poneleit, Kathy AU - Crane, Elizabeth AU - Budnitz, Daniel S AD - Centers for Disease Control and Prevention, Division of Healthcare Quality Promotion Y1 - 2011/05// PY - 2011 DA - May 2011 SP - 312 EP - 317 PB - Association of Schools of Public Health, Washington DC VL - 126 IS - 3 SN - 0033-3549, 0033-3549 KW - Health conditions and policy - Health and health policy KW - Health conditions and policy - Diseases and disorders KW - Manufacturing and heavy industry - Pharmaceutical industry KW - Population groups, population policy, and demographics - Demography and census KW - Influenza KW - Population KW - Drugs KW - Public health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/908014098?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Public+Health+Reports&rft.atitle=Emergency+Department+Visits+for+Antiviral+Adverse+Events+During+the+2009+H1N1+Influenza+Pandemic&rft.au=Lovegrove%2C+Maribeth+C%3BShehab%2C+Nadine%3BHales%2C+Craig+M%3BPoneleit%2C+Kathy%3BCrane%2C+Elizabeth%3BBudnitz%2C+Daniel+S&rft.aulast=Lovegrove&rft.aufirst=Maribeth&rft.date=2011-05-01&rft.volume=126&rft.issue=3&rft.spage=312&rft.isbn=&rft.btitle=&rft.title=Public+Health+Reports&rft.issn=00333549&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2011-12-01 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Public health; Influenza; Drugs; Population ER - TY - JOUR T1 - Detection of Mycoplasma pneumoniae, Chlamydia pneumoniae, and Legionella spp. in clinical specimens using a single-tube multiplex real-time PCR assay AN - 907160979; 14878477 AB - A multiplex real-time PCR assay for the detection of Mycoplasma pneumoniae (MP181), Chlamydia (Chlamydophila) pneumoniae (CP-Arg), Legionella spp. (Pan-Leg), and the human RNase P (RNase P) gene was developed for rapid testing of atypical bacterial respiratory pathogens in clinical specimens. This method uses 4 distinct hydrolysis probes to detect 3 leading causes of community-acquired pneumonia. The assay was evaluated for specificity and sensitivity by testing against 35 related organisms, a dilution series of each specific target and 197 clinical specimens. Specificity testing demonstrated no cross-reactivity. A comparison to previously validated singleplex real-time PCR assays for each agent was also performed. The analytical sensitivity for specific pathogen targets in both the singleplex and multiplex was identical (50 fg), while efficiencies ranged from 82% to 97% for the singleplex assays and from 90% to 100% for the multiplex assay. The clinical sensitivity of the multiplex assay was improved for the Pan-Leg and CP-Arg targets when compared to the singleplex. The MP181 assay displayed equivalent performance. This multiplex assay provides an overall improvement in the diagnostic capability for these agents by demonstrating a sensitive, high-throughput and rapid method. This procedure may allow for a practical and efficient means to test respiratory clinical specimens for atypical pneumonia agents in health care settings and facilitate an appropriate public health response to outbreaks. JF - Diagnostic Microbiology and Infectious Disease AU - Thurman, Kathleen A AU - Warner, Agnes K AU - Cowart, Kelley C AU - Benitez, Alvaro J AU - Winchell, Jonas M AD - Respiratory Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA, jwinchell@cdc.gov Y1 - 2011/05// PY - 2011 DA - May 2011 SP - 1 EP - 9 PB - Elsevier Science, Box 882 New York NY 10159 USA VL - 70 IS - 1 SN - 0732-8893, 0732-8893 KW - Microbiology Abstracts B: Bacteriology KW - Real-time PCR KW - Multiplex real-time PCR KW - Community-acquired pneumonia KW - Cross-reactivity KW - Probes KW - Polymerase chain reaction KW - Pathogens KW - Chlamydophila pneumoniae KW - Mycoplasma pneumoniae KW - Hydrolysis KW - Legionella KW - Pneumonia KW - Ribonuclease P KW - Public health KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/907160979?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Diagnostic+Microbiology+and+Infectious+Disease&rft.atitle=Detection+of+Mycoplasma+pneumoniae%2C+Chlamydia+pneumoniae%2C+and+Legionella+spp.+in+clinical+specimens+using+a+single-tube+multiplex+real-time+PCR+assay&rft.au=Thurman%2C+Kathleen+A%3BWarner%2C+Agnes+K%3BCowart%2C+Kelley+C%3BBenitez%2C+Alvaro+J%3BWinchell%2C+Jonas+M&rft.aulast=Thurman&rft.aufirst=Kathleen&rft.date=2011-05-01&rft.volume=70&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Diagnostic+Microbiology+and+Infectious+Disease&rft.issn=07328893&rft_id=info:doi/10.1016%2Fj.diagmicrobio.2010.11.014 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2016-07-07 N1 - SubjectsTermNotLitGenreText - Cross-reactivity; Probes; Polymerase chain reaction; Pathogens; Hydrolysis; Ribonuclease P; Pneumonia; Public health; Mycoplasma pneumoniae; Chlamydophila pneumoniae; Legionella DO - http://dx.doi.org/10.1016/j.diagmicrobio.2010.11.014 ER - TY - JOUR T1 - A Social Marketing Approach to Building a Behavioral Intervention for Congenital Cytomegalovirus AN - 896166493; 201116190 AB - Congenital cytomegalovirus (CMV) is the most common congenital infection in the United States, causing permanent disabilities in more than 5,500 children born each year. In the absence of a vaccine, a promising means of prevention is through a behavioral intervention that educates women about CMV and promotes adherence to hygiene guidelines during pregnancy. Although effective behavioral interventions have been identified for other infectious diseases with similar transmission modes, current research has not yet identified an effective intervention for CMV. One way to gather evidence and identify key elements of a successful CMV intervention is through a social marketing approach. This article describes a five-step process for applying social marketing principles to the research and development, implementation, and evaluation of a CMV behavioral intervention. [Reprinted by permission of Sage Publications Inc., copyright holder.] JF - Health Promotion Practice AU - Bate, Sheri Lewis AU - Cannon, Michael J AD - National Center for Immunization and Respiratory Diseases at the Centers for Disease Control and Prevention in Atlanta, Georgia Y1 - 2011/05// PY - 2011 DA - May 2011 SP - 349 EP - 360 PB - Sage Publications, Thousand Oaks CA VL - 12 IS - 3 SN - 1524-8399, 1524-8399 KW - congenital cytomegalovirus cytomegalovirus social marketing behavioral intervention maternal and infant health KW - Social marketing KW - Adherence KW - Women KW - Pregnant women KW - Hygiene KW - Cytomegalovirus KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/896166493?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+Promotion+Practice&rft.atitle=A+Social+Marketing+Approach+to+Building+a+Behavioral+Intervention+for+Congenital+Cytomegalovirus&rft.au=Bate%2C+Sheri+Lewis%3BCannon%2C+Michael+J&rft.aulast=Bate&rft.aufirst=Sheri&rft.date=2011-05-01&rft.volume=12&rft.issue=3&rft.spage=349&rft.isbn=&rft.btitle=&rft.title=Health+Promotion+Practice&rft.issn=15248399&rft_id=info:doi/10.1177%2F1524839909336329 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2011-10-03 N1 - Number of references - 81 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Social marketing; Cytomegalovirus; Pregnant women; Hygiene; Women; Adherence DO - http://dx.doi.org/10.1177/1524839909336329 ER - TY - JOUR T1 - Vector Competence of the Stable Fly (Diptera: Muscidae) for West Nile Virus AN - 893270293; 14933956 AB - In 2006--2007, stable flies, Stomoxys calcitrans (L.) (Diptera: Muscidae), were suspected of being enzootic vectors of West Nile virus (family Flaviviridae, genus Flavivirus, WNV) during a die-off of American white pelicans (Pelecanus erythrorhynchos Gmelin) (Pelecanidae) in Montana, USA. WNV-positive stable flies were observed feeding en masse on incapacitated, WNV-positive pelicans, arousing suspicions that the flies could have been involved in WNV transmission among pelicans, and perhaps to livestock and humans. We assessed biological transmission by infecting stable flies intrathoracically with WNV and testing them at 2-d intervals over 20 d. Infectious WNV was detected in fly bodies in decreasing amounts over time for only the first 6 d postinfection, an indication that WNV did not replicate within fly tissues and that stable flies cannot biologically transmit WNV. We assessed mechanical transmission using a novel technique. Specifically, we fed WNV-infected blood to individual flies by using a cotton swab (i.e., artificial donor), and at intervals of 1 min--24 h, we allowed flies to refeed on a different swab saturated with WNV-negative blood (i.e., artificial recipient). Flies mechanically transmitted viable WNV from donor to recipient swabs for up to 6 h postinfection, with the majority of the transmission events occurring within the first hour. Flies mechanically transmitted WNV RNA to recipient swabs for up to 24 h, mostly within the first 6 h. Given its predilection to feed multiple times when disturbed, these findings support the possibility that the stable fly could mechanically transmit WNV. JF - Journal of Medical Entomology AU - Doyle, Michael S AU - Swope, Bethany N AU - Hogsette, Jerome A AU - Burkhalter, Kristen L AU - Savage, Harry M AU - Nasci, Roger S Y1 - 2011/05// PY - 2011 DA - May 2011 SP - 656 EP - 668 PB - Entomological Society of America, 9301 Annapolis Rd. Lanham MD 20706 USA VL - 48 IS - 3 SN - 0022-2585, 0022-2585 KW - Virology & AIDS Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Entomology Abstracts KW - Stomoxys calcitrans KW - biological transmission KW - mechanical transmission KW - Pelecanus erythrorhynchos KW - West Nile virus KW - Marine KW - Feeding KW - Marine birds KW - Cotton KW - Vectors KW - Hosts KW - Flaviviridae KW - Flavivirus KW - Entomology KW - Livestock KW - Disease transmission KW - Blood KW - RNA KW - Viral diseases KW - Diptera KW - Muscidae KW - Aquatic insects KW - USA, Montana KW - Pelecanidae KW - V 22300:Methods KW - Q1 08484:Species interactions: parasites and diseases KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/893270293?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Medical+Entomology&rft.atitle=Vector+Competence+of+the+Stable+Fly+%28Diptera%3A+Muscidae%29+for+West+Nile+Virus&rft.au=Doyle%2C+Michael+S%3BSwope%2C+Bethany+N%3BHogsette%2C+Jerome+A%3BBurkhalter%2C+Kristen+L%3BSavage%2C+Harry+M%3BNasci%2C+Roger+S&rft.aulast=Doyle&rft.aufirst=Michael&rft.date=2011-05-01&rft.volume=48&rft.issue=3&rft.spage=656&rft.isbn=&rft.btitle=&rft.title=Journal+of+Medical+Entomology&rft.issn=00222585&rft_id=info:doi/10.1603%2FME10167 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-09-01 N1 - Number of references - 3 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Marine birds; Viral diseases; Hosts; Aquatic insects; Entomology; Disease transmission; Feeding; Blood; Cotton; RNA; Vectors; Livestock; Stomoxys calcitrans; Pelecanus erythrorhynchos; Muscidae; Diptera; West Nile virus; Flavivirus; Flaviviridae; Pelecanidae; USA, Montana; Marine DO - http://dx.doi.org/10.1603/ME10167 ER - TY - JOUR T1 - Human papillomavirus vaccine coverage in the United States, National Health and Nutrition Examination Survey, 2007-2008 AN - 885054284; 14768192 AB - This study aims to estimate human papillomavirus (HPV) vaccine coverage by demographic and sexual behavior characteristics 1-2 years after vaccine licensure in a nationally representative sample of females aged 9-59 years in the United States . Methods: In 2007-2008, a total of 2775 females aged 9-59 years responded to questions on HPV vaccine receipt in the National Health and Nutrition Examination Survey (NHANES). Demographic and sexual characteristics were evaluated for select age categories in bivariate analyses after adjusting for survey design. Results: Overall, 15.2% of females aged 11-26 years reported HPV vaccine initiation; vaccine initiation varied significantly by age. We found no significant difference in vaccine initiation by race or poverty level in either 11-18 or 19-26-year olds. Significantly more 19-26-year olds with private insurance initiated vaccine (16.3%) than those with public insurance (4.0%) (p = 0.04). Among females aged 14-18 years, vaccine initiation was higher in those who ever had sex (28.6%) compared to those who had never had sex (17.8%) (p = 0.05). Conclusions: These results describe HPV vaccine initiation shortly after vaccine licensure. Vaccine initiation was highest in females aged 14-18 years. Efforts should be made to increase HPV vaccine coverage for the recommended age groups. JF - Preventive Medicine AU - Taylor, La'Shan D AU - Hariri, Susan AU - Sternberg, Maya AU - Dunne, Eileen F AU - Markowitz, Lauri E AD - National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, 1600 Clifton Rd, N.E., Mailstop E-02, Atlanta, GA 30333, USA, LDTaylor@cdc.gov Y1 - 2011/05/01/ PY - 2011 DA - 2011 May 01 SP - 398 EP - 400 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 52 IS - 5 SN - 0091-7435, 0091-7435 KW - Virology & AIDS Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - demography KW - sexual behavior KW - vaccines KW - Age KW - Nutrition KW - Sexual behavior KW - Demography KW - poverty KW - Races KW - Sex KW - age groups KW - Insurance KW - USA KW - Vaccines KW - Human papillomavirus KW - R2 23060:Medical and environmental health KW - V 22400:Human Diseases KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/885054284?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Preventive+Medicine&rft.atitle=Human+papillomavirus+vaccine+coverage+in+the+United+States%2C+National+Health+and+Nutrition+Examination+Survey%2C+2007-2008&rft.au=Taylor%2C+La%27Shan+D%3BHariri%2C+Susan%3BSternberg%2C+Maya%3BDunne%2C+Eileen+F%3BMarkowitz%2C+Lauri+E&rft.aulast=Taylor&rft.aufirst=La%27Shan&rft.date=2011-05-01&rft.volume=52&rft.issue=5&rft.spage=398&rft.isbn=&rft.btitle=&rft.title=Preventive+Medicine&rft.issn=00917435&rft_id=info:doi/10.1016%2Fj.ypmed.2010.11.006 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-08-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Demography; Age; Vaccines; Sexual behavior; Nutrition; Races; Sex; demography; age groups; sexual behavior; vaccines; poverty; Insurance; Human papillomavirus; USA DO - http://dx.doi.org/10.1016/j.ypmed.2010.11.006 ER - TY - JOUR T1 - Sexual Homicide and Sexual Violence-Associated Homicide: Findings From the National Violent Death Reporting System AN - 876232600; 14895338 AB - Sexual violence is linked to homicide in a variety of ways. In this study the authors analyzed narratives that described the homicide circumstances of 285 homicide victims from 17 states who participated in the National Violent Death Reporting System during 2003-2007. The authors discuss a narrative analysis conducted using qualitative methods that revealed four categories of homicide linked to sexual violence, in addition to classic sexual homicide. In this article, the authors provide descriptions of the circumstances involved in sexual violence-related homicides, narrative examples of each type, and offer an expanded classification of these crimes. The analyses reveal specific types of homicide that are related to the perpetration of sexual violence, some of which have received little to no attention in the sexual violence or homicide literature. The study demonstrates the potential of the NVDRS as a strong data source for sexual homicides as well as other forms of homicide. Finally, the authors discuss implications for ongoing monitoring of homicides that are linked to sexual violence. JF - Homicide Studies AU - Smith, Sharon G AU - Basile, Kathleen C AU - Karch, Debra AD - Centers for Disease Control and Prevention, Atlanta, GA, SSmith4@cdc.gov Y1 - 2011/05// PY - 2011 DA - May 2011 SP - 132 EP - 153 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU UK VL - 15 IS - 2 SN - 1088-7679, 1088-7679 KW - Risk Abstracts KW - Mortality KW - homicide KW - crime KW - classification KW - sexual assault KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/876232600?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Homicide+Studies&rft.atitle=Sexual+Homicide+and+Sexual+Violence-Associated+Homicide%3A+Findings+From+the+National+Violent+Death+Reporting+System&rft.au=Smith%2C+Sharon+G%3BBasile%2C+Kathleen+C%3BKarch%2C+Debra&rft.aulast=Smith&rft.aufirst=Sharon&rft.date=2011-05-01&rft.volume=15&rft.issue=2&rft.spage=132&rft.isbn=&rft.btitle=&rft.title=Homicide+Studies&rft.issn=10887679&rft_id=info:doi/10.1177%2F1088767911406236 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-07-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Mortality; homicide; crime; classification; sexual assault DO - http://dx.doi.org/10.1177/1088767911406236 ER - TY - JOUR T1 - Trends in obesity and abdominal obesity among adults in the United States from 1999-2008 AN - 876224954; 14865502 AB - Background and Objective: The United States has experienced a large increase in the prevalence of obesity since the 1970s. Our objective was to describe recent trends in obesity and abdominal obesity among adults in the United States.Design:Trend study of cross-sectional studies.Subjects:We used data from up to 22872 men and non-pregnant women aged greater than or equal to 20 years from the National Health and Nutrition Examination Survey (NHANES) 1999-2008.Main Outcome Measures:Main outcome measures are mean body mass index and waist circumference, percentages of obesity and abdominal obesity. Obesity was defined as a body mass index greater than or equal to 30kgm super(-2), and abdominal obesity was defined as a waist circumference greater than or equal to 102cm in men and greater than or equal to 88cm in women. Results: In men, the age-adjusted mean body mass index, mean waist circumference, and prevalence of obesity and abdominal obesity were 27.8kgm super(-2), 99.1cm, and 26.9 and 37.8%, respectively, during 1999-2000 and 28.5kgm super(-2) (P sub(trend)=0.001), 100.8cm (P sub(trend)=0.002), and 32.0 (P sub(trend)=0.001) and 43.7% (P sub(trend)=0.002), respectively, during 2007-2008. In women, the age-adjusted mean body mass index, mean waist circumference, and prevalence of obesity and abdominal obesity were 28.2kgm super(-2), 92.2cm, and 33.2 and 55.8%, respectively, during 1999-2000 and 28.6kgm super(-2) (P sub(trend)=0.181), 94.9cm (P sub(trend)=0.006), and 35.2 (P sub(trend)=0.180) and 61.8% (P sub(trend)=0.036), respectively, during 2007-2008. Significant linear trends for increasing prevalence of obesity were noted among men with the least and most education. Conclusion: Between 1999 and 2008, both obesity and abdominal obesity increased in men, and abdominal obesity increased in women. JF - International Journal of Obesity AU - Ford, E S AU - Li, C AU - Zhao, G AU - Tsai, J AD - Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA Y1 - 2011/05// PY - 2011 DA - May 2011 SP - 736 EP - 743 PB - Nature Publishing Group, The Macmillan Building London N1 9XW UK VL - 35 IS - 5 SN - 0307-0565, 0307-0565 KW - Physical Education Index; Health & Safety Science Abstracts KW - Adults KW - Body mass KW - Education KW - Evaluation KW - Men KW - Nutrition KW - Obesity KW - Trends KW - Waist KW - Women KW - body mass KW - obesity KW - USA KW - H 12000:Epidemiology and Public Health KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/876224954?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Obesity&rft.atitle=Trends+in+obesity+and+abdominal+obesity+among+adults+in+the+United+States+from+1999-2008&rft.au=Ford%2C+E+S%3BLi%2C+C%3BZhao%2C+G%3BTsai%2C+J&rft.aulast=Ford&rft.aufirst=E&rft.date=2011-05-01&rft.volume=35&rft.issue=5&rft.spage=736&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Obesity&rft.issn=03070565&rft_id=info:doi/10.1038%2Fijo.2010.186 LA - English DB - Physical Education Index; ProQuest Environmental Science Collection N1 - Date revised - 2011-07-01 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - Evaluation; Obesity; Education; Waist; Men; Body mass; Women; Adults; Trends; body mass; obesity; Nutrition; USA DO - http://dx.doi.org/10.1038/ijo.2010.186 ER - TY - JOUR T1 - Adherence to the 2008 Adult Physical Activity Guidelines and Mortality Risk AN - 867749063; 14695087 AB - Mortality differentials by level and intensity of physical activity have been widely documented. A comprehensive review of scientific evidence of the health benefits of physical activity led the USDHHS to issue new Federal Guidelines for physical activity in 2008. Reductions in mortality risk associated with adherence to these Guidelines among the general U.S. adult population have not yet been studied This study compared the relative mortality risks of U.S. adults who met the 2008 Guidelines with adults who did not meet the recommendations. Methods: Cox proportional hazards models were used to examine the relative mortality risks of U.S. adults aged >=18 years, using data from the 1997-2004 National Health Interview Survey and linked mortality records for deaths occurring in 1997-2006 (analyzed in 2010). Risks for adults with and without chronic health conditions were examined separately. Results: Meeting the recommendations for aerobic activity was associated with substantial survival benefits, especially among the population having chronic conditions, with estimated hazard ratios ranging from 0.65 to 0.75 (p<0.05). While strengthening activities by themselves did not appear to reduce mortality risks, they may provide added survival benefits to those already engaged in aerobic activities. The relative benefits of physical activity were greatest among adults who had at least one chronic condition. Conclusions: Adherence to the 2008 Physical Activity Guidelines was associated with reduced all-cause mortality risks among U.S. adults, after controlling for sociodemographic characteristics,I, smoking, and alcohol use. JF - American Journal of Preventive Medicine AU - Schoenborn, Charlotte A AU - Stommel, Manfred AD - Division of Health Interview Statistics, National Center for Health Statistics/CDC, Hyattsville, Maryland, cas6@cdc.gov Y1 - 2011/05// PY - 2011 DA - May 2011 SP - 514 EP - 521 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 40 IS - 5 SN - 0749-3797, 0749-3797 KW - Physical Education Index; Risk Abstracts KW - Mortality KW - Alcohol KW - Death KW - Aerobics KW - Compliance KW - Adults KW - Exercise KW - Smoking KW - USA KW - guidelines KW - Reviews KW - Analysis KW - Health (hazards) KW - Interviews KW - physical activity KW - survival KW - R2 23060:Medical and environmental health KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/867749063?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Adherence+to+the+2008+Adult+Physical+Activity+Guidelines+and+Mortality+Risk&rft.au=Schoenborn%2C+Charlotte+A%3BStommel%2C+Manfred&rft.aulast=Schoenborn&rft.aufirst=Charlotte&rft.date=2011-05-01&rft.volume=40&rft.issue=5&rft.spage=514&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2010.12.029 LA - English DB - Physical Education Index; ProQuest Environmental Science Collection N1 - Date revised - 2011-05-01 N1 - Last updated - 2013-11-15 N1 - SubjectsTermNotLitGenreText - Alcohol; Death; Aerobics; Analysis; Compliance; Health (hazards); Interviews; Exercise; Adults; Smoking; Mortality; guidelines; Reviews; survival; physical activity; USA DO - http://dx.doi.org/10.1016/j.amepre.2010.12.029 ER - TY - JOUR T1 - Persistence of deposited metals in the lungs after stainless steel and mild steel welding fume inhalation in rats. AN - 865694112; 20924559 AB - Welding generates complex metal fumes that vary in composition. The objectives of this study were to compare the persistence of deposited metals and the inflammatory potential of stainless and mild steel welding fumes, the two most common fumes used in US industry. Sprague-Dawley rats were exposed to 40 mg/m(3) of stainless or mild steel welding fumes for 3 h/day for 3 days. Controls were exposed to filtered air. Generated fume was collected, and particle size and elemental composition were determined. Bronchoalveolar lavage was done on days 0, 8, 21, and 42 after the last exposure to assess lung injury/inflammation and to recover lung phagocytes. Non-lavaged lung samples were analyzed for total and specific metal content as a measure of metal persistence. Both welding fumes were similar in particle morphology and size. Following was the chemical composition of the fumes-stainless steel: 57% Fe, 20% Cr, 14% Mn, and 9% Ni; mild steel: 83% Fe and 15% Mn. There was no effect of the mild steel fume on lung injury/inflammation at any time point compared to air control. Lung injury and inflammation were significantly elevated at 8 and 21 days after exposure to the stainless steel fume compared to control. Stainless steel fume exposure was associated with greater recovery of welding fume-laden macrophages from the lungs at all time points compared with the mild steel fume. A higher concentration of total metal was observed in the lungs of the stainless steel welding fume at all time points compared with the mild steel fume. The specific metals present in the two fumes were cleared from the lungs at different rates. The potentially more toxic metals (e.g., Mn, Cr) present in the stainless steel fume were cleared from the lungs more quickly than Fe, likely increasing their translocation from the respiratory system to other organs. JF - Archives of toxicology AU - Antonini, James M AU - Roberts, Jenny R AU - Stone, Samuel AU - Chen, Bean T AU - Schwegler-Berry, Diane AU - Chapman, Rebecca AU - Zeidler-Erdely, Patti C AU - Andrews, Ronnee N AU - Frazer, David G AD - Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA. jga6@cdc.gov Y1 - 2011/05// PY - 2011 DA - May 2011 SP - 487 EP - 498 VL - 85 IS - 5 KW - Air Pollutants, Occupational KW - 0 KW - Gases KW - Metals KW - Stainless Steel KW - 12597-68-1 KW - Index Medicus KW - Models, Animal KW - Animals KW - Lung Injury -- chemically induced KW - Particle Size KW - Inflammation -- chemically induced KW - Bronchoalveolar Lavage KW - Rats KW - Rats, Sprague-Dawley KW - Phagocytosis -- drug effects KW - Lung Injury -- pathology KW - Male KW - Inflammation -- pathology KW - Macrophages -- metabolism KW - Metals -- toxicity KW - Gases -- analysis KW - Stainless Steel -- toxicity KW - Inhalation Exposure KW - Lung -- drug effects KW - Welding KW - Lung -- pathology KW - Air Pollutants, Occupational -- toxicity KW - Gases -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/865694112?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Archives+of+toxicology&rft.atitle=Persistence+of+deposited+metals+in+the+lungs+after+stainless+steel+and+mild+steel+welding+fume+inhalation+in+rats.&rft.au=Antonini%2C+James+M%3BRoberts%2C+Jenny+R%3BStone%2C+Samuel%3BChen%2C+Bean+T%3BSchwegler-Berry%2C+Diane%3BChapman%2C+Rebecca%3BZeidler-Erdely%2C+Patti+C%3BAndrews%2C+Ronnee+N%3BFrazer%2C+David+G&rft.aulast=Antonini&rft.aufirst=James&rft.date=2011-05-01&rft.volume=85&rft.issue=5&rft.spage=487&rft.isbn=&rft.btitle=&rft.title=Archives+of+toxicology&rft.issn=1432-0738&rft_id=info:doi/10.1007%2Fs00204-010-0601-1 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-08-16 N1 - Date created - 2011-05-09 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1007/s00204-010-0601-1 ER - TY - JOUR T1 - Characterization of lead in US workplaces using data from OSHA's integrated management information system AN - 1017968360; 16691559 AB - Background Lead hazards continue to be encountered in the workplace. OSHA's Integrated Management Information System (IMIS) is the largest available database containing sampling results in US workplaces. Methods Personal airborne lead sampling results in IMIS were extracted for years 1979-2008. Descriptive analyses, geographical mapping, and regression modeling of results were performed. Results Seventy-nine percent of lead samples were in the manufacturing sector. Lead sample results were highest in the construction sector (median=0.03mg/m3). NORA sector, year, OSHA region, number of employees at the worksite, federal/state OSHA plan, unionization, advance notification, and presence of an employee representative were statistically associated with having a lead sample result exceed the PEL. Conclusions Lead concentrations within construction have been higher than any other industry. Lead hazards have been most prevalent in the north and northeastern US. IMIS data can be useful as a surveillance tool and for targeting prevention efforts toward hazardous industries. Am. J. Ind. Med. 54:356-365, 2011. ? 2011 Wiley-Liss, Inc. JF - American Journal of Industrial Medicine AU - Henn, Scott A AU - Sussell, Aaron L AU - Li, Jia AU - Shire, Jeffrey D AU - Alarcon, Walter A AU - Tak, Sangwoo Y1 - 2011/05// PY - 2011 DA - May 2011 SP - 356 EP - 365 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 54 IS - 5 SN - 1097-0274, 1097-0274 KW - Toxicology Abstracts; Health & Safety Science Abstracts KW - Manufacturing industry KW - Federal regulations KW - Safety regulations KW - Data processing KW - Working conditions KW - Lead KW - Databases KW - USA KW - Prevention KW - Sampling KW - Mapping KW - Information systems KW - H 1000:Occupational Safety and Health KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1017968360?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Characterization+of+lead+in+US+workplaces+using+data+from+OSHA%27s+integrated+management+information+system&rft.au=Henn%2C+Scott+A%3BSussell%2C+Aaron+L%3BLi%2C+Jia%3BShire%2C+Jeffrey+D%3BAlarcon%2C+Walter+A%3BTak%2C+Sangwoo&rft.aulast=Henn&rft.aufirst=Scott&rft.date=2011-05-01&rft.volume=54&rft.issue=5&rft.spage=356&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=10970274&rft_id=info:doi/10.1002%2Fajim.20926 L2 - http://onlinelibrary.wiley.com/doi/10.1002/ajim.20926/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2014-11-12 N1 - SubjectsTermNotLitGenreText - Databases; Data processing; Mapping; Sampling; Lead; Information systems; Manufacturing industry; Prevention; Federal regulations; Safety regulations; Working conditions; USA DO - http://dx.doi.org/10.1002/ajim.20926 ER - TY - JOUR T1 - The estimated national burden of physical ergonomic hazards among US workers AN - 1017966978; 16691563 AB - Purpose To estimate the national burden of physical ergonomic hazards among working adults in the US. Methods We estimated the population prevalence of and the total number of workers who are exposed to physical ergonomic hazards, such as vibration, working in cramped space, kneeling, body bending or twisting, climbing, and repetitive motions using Occupational Information Network (O*NET) data and the Occupational Employment Statistics (OES) from the U.S. Bureau of Labor Statistics (BLS) stratified by occupation title. Results Repetitive motion was the most prevalent of all ergonomic hazards (27% of US workers are estimated to be exposed continually). Bending or twisting of the body more than half their time at work was also common, involving over 32 million US workers (25% of US workforce). Kneeling, crouching, stooping, or crawling was another ergonomic hazard that 14 million US workers perform more than half their time at work. Almost 4 million workers climb ladders, scaffolds, poles, etc. for more than half their time at work. We estimate that over 13 million workers (10% of US workforce) were exposed to cramped workspace that requires getting into awkward positions every day. Finally, about 3.5 million workers (2.7% of US workforce) were estimated to be exposed to whole body vibration every day. Conclusion A large portion of the US work force is exposed to ergonomic hazards known to be associated with musculoskeletal disorders (MSDs). The occupations with the highest prevalence of each ergonomic hazard may be deserving of prompt efforts toward prevention of MSDs. Am. J. Ind. Med. 54:395-404, 2011. ? 2010 Wiley-Liss, Inc. JF - American Journal of Industrial Medicine AU - Tak, Sangwoo AU - Calvert, Geoffrey M Y1 - 2011/05// PY - 2011 DA - May 2011 SP - 395 EP - 404 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 54 IS - 5 SN - 1097-0274, 1097-0274 KW - Health & Safety Science Abstracts KW - Ergonomics KW - Hazards KW - Occupational health KW - Vibration KW - employment KW - musculoskeletal system KW - prevention KW - working conditions KW - USA KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1017966978?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=The+estimated+national+burden+of+physical+ergonomic+hazards+among+US+workers&rft.au=Tak%2C+Sangwoo%3BCalvert%2C+Geoffrey+M&rft.aulast=Tak&rft.aufirst=Sangwoo&rft.date=2011-05-01&rft.volume=54&rft.issue=5&rft.spage=395&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=10970274&rft_id=info:doi/10.1002%2Fajim.20883 L2 - http://onlinelibrary.wiley.com/doi/10.1002/ajim.20883/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2012-06-01 N1 - SubjectsTermNotLitGenreText - Hazards; employment; Vibration; prevention; musculoskeletal system; working conditions; Ergonomics; Occupational health; USA DO - http://dx.doi.org/10.1002/ajim.20883 ER - TY - JOUR T1 - Healthcare-use for Major Infectious Disease Syndromes in an Informal Settlement in Nairobi, Kenya AN - 925741360; 201203723 AB - A healthcare-use survey was conducted in the Kibera informal settlement in Nairobi, Kenya, in July 2005 to inform subsequent surveillance in the site for infectious diseases. Sets of standardized questionnaires were administered to 1,542 caretakers and heads of households with one or more child(ren) aged less than five years. The average household-size was 5.1 (range 1-15) persons. Most (90%) resided in a single room with monthly rents of US$ 4.50-7.00. Within the previous two weeks, 49% of children (n=1,378) aged less than five years (under-five children) and 18% of persons (n=1,139) aged =5 years experienced febrile, diarrhoeal or respiratory illnesses. The large majority (>75%) of illnesses were associated with health care-seeking. While licensed clinics were the most-frequently visited settings, kiosks, unlicensed care providers, and traditional healers were also frequently visited. Expense was cited most often (50%) as the reason for not seeking healthcare. Of those who sought healthcare, 34-44% of the first and/or the only visits were made with non-licensed care providers, potentially delaying opportunities for early optimal intervention. Adapted from the source document. JF - Journal of Health, Population and Nutrition AU - Breiman, Robert F AU - Olack, Beatrice AU - Shultz, Alvin AU - Roder, Sanam AU - Kimani, Kabuiya AU - Feikin, Daniel R AU - Burke, Heather AD - Kenya Medical Research Institute-CDC rbreiman@ke.cdc.gov Y1 - 2011/04// PY - 2011 DA - April 2011 SP - 123 EP - 133 PB - ICDDR, B, Dhaka, Bangladesh VL - 29 IS - 2 SN - 1606-0997, 1606-0997 KW - Acute respiratory infection KW - Diarrhoeal diseases KW - Febrile illness KW - Healthcare-seeking KW - Health care use KW - Informal settlements KW - Pneumonia KW - Slums KW - Urbanization KW - Kenya KW - Health professionals KW - Health care KW - Settlements KW - Rents KW - Children KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/925741360?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Health%2C+Population+and+Nutrition&rft.atitle=Healthcare-use+for+Major+Infectious+Disease+Syndromes+in+an+Informal+Settlement+in+Nairobi%2C+Kenya&rft.au=Breiman%2C+Robert+F%3BOlack%2C+Beatrice%3BShultz%2C+Alvin%3BRoder%2C+Sanam%3BKimani%2C+Kabuiya%3BFeikin%2C+Daniel+R%3BBurke%2C+Heather&rft.aulast=Breiman&rft.aufirst=Robert&rft.date=2011-04-01&rft.volume=29&rft.issue=2&rft.spage=123&rft.isbn=&rft.btitle=&rft.title=Journal+of+Health%2C+Population+and+Nutrition&rft.issn=16060997&rft_id=info:doi/ L2 - http://www.icddrb.org/jhpn LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2012-03-01 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Settlements; Health care; Kenya; Health professionals; Children; Rents ER - TY - JOUR T1 - Discovery and Phylogenetic Analysis of Novel Members of Class b Enterotoxigenic Escherichia coli Adhesive Fimbriae AN - 899147104; 15403981 AB - Enterotoxigenic Escherichia coli (ETEC) is recognized to be a common cause of acute watery diarrhea in children from developing countries. Colonization factors (CFAs) have been identified predominantly in ETEC isolates secreting heat-stable enterotoxin (ST) or cosecreting ST with a heat-labile toxin (LT). We hypothesized that LT-only-secreting ETEC produces unique colonization factors not previously described in ST and LTST-secreting ETEC. A set of degenerate primers based on nucleotide sequence similarities between the major structural genes of CS20 (csnA), CS18 (fotA), CS12 (cswA), and porcine antigen 987 (fasA) was developed and used to screen a collection of 266 LT-secreting ETEC isolates in which no known CFA was detected. PCR-amplified products of different molecular masses were obtained from 49 (18.4%) isolates. Nucleotide sequence analysis of the PCR amplicons followed by GenBank nucleotide BLASTn analysis revealed five novel DNA sequences; translated amino acid BLASTx analysis confirmed sequence similarity to class 1b major structural proteins encoded by csnA, fotA, and fasA. Strains expressing the novel CFAs were phylotyped and analyzed using multilocus sequence typing (MLST; Achtman scheme), and the types detected were compared to those of a collection of archived global E. coli strains. In conclusion, application of the degenerate primer sets to ETEC isolates from surveillance studies increased the total number of ETEC isolates with detectable CFAs by almost 20%. Additionally, MLST analysis suggests that for many CFAs, there may be a requirement for certain genetic backgrounds to acquire and maintain plasmids carrying genes encoding CFAs. JF - Journal of Clinical Microbiology AU - Nada, Rania A AU - Shaheen, Hind I AU - Khalil, Sami B AU - Mansour, Adel AU - El-Sayed, Nasr AU - Touni, Iman AU - Weiner, Matthew AU - Armstrong, Adam W AU - Klena, John D AD - U.S. Naval Medical Research Unit No. 3, Cairo, Egypt, irc4@cn.cdc.gov Y1 - 2011/04// PY - 2011 DA - Apr 2011 SP - 1403 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 United States VL - 49 IS - 4 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Phylogeny KW - Diarrhea KW - Nucleotide sequence KW - Children KW - Plasmids KW - Structural proteins KW - Toxins KW - multilocus sequence typing KW - Pili KW - Escherichia coli KW - Polymerase chain reaction KW - Enterotoxins KW - Primers KW - Thermal stability KW - Adhesives KW - Developing countries KW - Colonization factor KW - Amino acid sequence KW - J 02310:Genetics & Taxonomy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/899147104?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Discovery+and+Phylogenetic+Analysis+of+Novel+Members+of+Class+b+Enterotoxigenic+Escherichia+coli+Adhesive+Fimbriae&rft.au=Nada%2C+Rania+A%3BShaheen%2C+Hind+I%3BKhalil%2C+Sami+B%3BMansour%2C+Adel%3BEl-Sayed%2C+Nasr%3BTouni%2C+Iman%3BWeiner%2C+Matthew%3BArmstrong%2C+Adam+W%3BKlena%2C+John+D&rft.aulast=Nada&rft.aufirst=Rania&rft.date=2011-04-01&rft.volume=49&rft.issue=4&rft.spage=1403&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.02006-10 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Number of references - 39 N1 - Last updated - 2013-07-15 N1 - SubjectsTermNotLitGenreText - Phylogeny; Diarrhea; Nucleotide sequence; Plasmids; Children; Toxins; Structural proteins; multilocus sequence typing; Pili; Polymerase chain reaction; Primers; Enterotoxins; Thermal stability; Adhesives; Developing countries; Colonization factor; Amino acid sequence; Escherichia coli DO - http://dx.doi.org/10.1128/JCM.02006-10 ER - TY - JOUR T1 - Associations Between Risk Behaviors and Suicidal Ideation and Suicide Attempts: Do Racial/Ethnic Variations in Associations Account for Increased Risk of Suicidal Behaviors Among Hispanic/Latina 9th- to 12th-Grade Female Students? AN - 888110135; 15409737 AB - The objective of this study was to identify factors that may account for the disproportionately high prevalence of suicidal behaviors among Hispanic/Latina youth by examining whether associations of health risk behaviors with suicidal ideation and suicide attempts vary by race/ethnicity among female students. Data from the school-based 2007 national Youth Risk Behavior Survey were analyzed. Analyses were conducted among female students in grades 9 through 12 and included 21 risk behaviors related to unintentional injuries and violence; tobacco use; alcohol and other drug use; sexual behaviors that contribute to unintended pregnancy and sexually transmitted infections, including human immunodeficiency virus; physical activity; obesity and weight control; and perceived health status. With the exception of physical activity behaviors and obesity, all risk behaviors examined were associated with suicidal ideation and suicide attempts. Associations of risk behaviors with suicidal ideation varied by race/ethnicity for 5 of 21 behaviors, and for 0 of 21 behaviors for suicide attempts. Stratified analyses provided little insight into factors that may account for the higher prevalence of suicidal behaviors among Hispanic/Latina female students. These results suggest that the increased risk of suicidal behaviors among Hispanic/Latina female students cannot be accounted for by differential associations with these selected risk behaviors. Other factors, such as family characteristics, acculturation, and the socio-cultural environment, should be examined in future research. JF - Archives of Suicide Research AU - Eaton, Danice K AU - Foti, Kathryn AU - Brener, Nancy D AU - Crosby, Alex E AU - Flores, Glenn AU - Kann, Laura AD - Division of Adolescent and School Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA Y1 - 2011/04// PY - 2011 DA - Apr 2011 SP - 113 EP - 126 PB - Taylor & Francis Group Ltd., 2 Park Square Oxford OX14 4RN United Kingdom VL - 15 IS - 2 SN - 1381-1118, 1381-1118 KW - Risk Abstracts KW - Alcohol KW - obesity KW - infectious diseases KW - Behavior KW - Human immunodeficiency virus KW - Perception KW - Tobacco KW - physical activity KW - Ethnic groups KW - suicide KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/888110135?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Archives+of+Suicide+Research&rft.atitle=Associations+Between+Risk+Behaviors+and+Suicidal+Ideation+and+Suicide+Attempts%3A+Do+Racial%2FEthnic+Variations+in+Associations+Account+for+Increased+Risk+of+Suicidal+Behaviors+Among+Hispanic%2FLatina+9th-+to+12th-Grade+Female+Students%3F&rft.au=Eaton%2C+Danice+K%3BFoti%2C+Kathryn%3BBrener%2C+Nancy+D%3BCrosby%2C+Alex+E%3BFlores%2C+Glenn%3BKann%2C+Laura&rft.aulast=Eaton&rft.aufirst=Danice&rft.date=2011-04-01&rft.volume=15&rft.issue=2&rft.spage=113&rft.isbn=&rft.btitle=&rft.title=Archives+of+Suicide+Research&rft.issn=13811118&rft_id=info:doi/10.1080%2F13811118.2011.565268 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-09-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Alcohol; infectious diseases; Behavior; Perception; Tobacco; obesity; physical activity; suicide; Ethnic groups; Human immunodeficiency virus DO - http://dx.doi.org/10.1080/13811118.2011.565268 ER - TY - JOUR T1 - Geographic variation of stature in Chinese youth of age 18+ AN - 876185500; 4211756 AB - The data is derived from a national survey on students constitution and health carried out by the government in 2005 in China. A total of 20707 subjects, 18-year-olds from 30 provinces and municipalities in China participated in this study. The differences of mean values of stature among different areas were compared. The 30 provinces and municipalities were divided into three groups: higher, middle and lower stature region. A map of stature distribution among Chinese youth was made, higher stature region is distributed mainly over the area around Bohai sea, north-east China and eastern coastal areas, and lower stature region is distributed mainly over the south of China. There was statistically significant correlation between the average stature of youth and the local GDP per capita, per capita annual consumption of eggs and average annual temperature. There were significant differences among districts in China. This difference is related to the local geographical conditions, socio-economic environment and genetic factors. Reprinted by permission of the publisher Kamla-Raj Enterprises, Delhi, India JF - Anthropologist AU - Ying-Xiu, Zhang AU - Shu-Rong, Wang AD - Shandong Center for Disease Control and Prevention ; Shandong Blood Center Y1 - 2011/04// PY - 2011 DA - Apr 2011 SP - 103 EP - 106 VL - 13 IS - 2 SN - 0972-0073, 0972-0073 KW - Anthropology KW - Government KW - Per capita income KW - Health KW - Students KW - Geography KW - China KW - Youth UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/876185500?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Anthropologist&rft.atitle=Geographic+variation+of+stature+in+Chinese+youth+of+age+18%2B&rft.au=Ying-Xiu%2C+Zhang%3BShu-Rong%2C+Wang&rft.aulast=Ying-Xiu&rft.aufirst=Zhang&rft.date=2011-04-01&rft.volume=13&rft.issue=2&rft.spage=103&rft.isbn=&rft.btitle=&rft.title=Anthropologist&rft.issn=09720073&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 13779 652 5676 646 6091; 5475; 12334 4049; 5551; 5772; 9380 6271; 93 116 30 ER - TY - JOUR T1 - The Decade of Action for Global Road Safety AN - 874191206; 14978500 JF - Journal of Safety Research AU - Sleet, David A AU - Baldwin, Grant AU - Dellinger, Ann AU - Dinh-Zarr, Bella AD - Division of Unintentional Injury Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia, dds6@cdc.gov Y1 - 2011/04// PY - 2011 DA - Apr 2011 SP - 147 EP - 148 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK VL - 42 IS - 2 SN - 0022-4375, 0022-4375 KW - Health & Safety Science Abstracts KW - traffic safety KW - H 2000:Transportation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/874191206?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Safety+Research&rft.atitle=The+Decade+of+Action+for+Global+Road+Safety&rft.au=Sleet%2C+David+A%3BBaldwin%2C+Grant%3BDellinger%2C+Ann%3BDinh-Zarr%2C+Bella&rft.aulast=Sleet&rft.aufirst=David&rft.date=2011-04-01&rft.volume=42&rft.issue=2&rft.spage=147&rft.isbn=&rft.btitle=&rft.title=Journal+of+Safety+Research&rft.issn=00224375&rft_id=info:doi/10.1016%2Fj.jsr.2011.02.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-06-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - traffic safety DO - http://dx.doi.org/10.1016/j.jsr.2011.02.001 ER - TY - JOUR T1 - Patients diagnosed with tuberculosis at death or who died during therapy: association with the human immunodeficiency virus AN - 867737297; 14691640 AB - OBJECTIVES: To describe trends and risk factors for tuberculosis (TB) mortality. DESIGN: We calculated trends, identified patient characteristics associated with TB diagnosis at death or death during TB treatment, and described diagnostic procedures using the United States National TB Surveillance System for 1997-2005. RESULTS: Human immunodeficiency virus (HIV) infected TB patients had an adjusted odds ratio (aOR) of 4-11 for TB diagnosis at death (foreign-born non-Whites, aOR=11) and of 3-19 for death during TB treatment vs. non-HIV-infected patients. Odds increased by age. Hispanic males had an aOR of 2 for TB diagnosis at death compared with female non-Hispanics. Multidrug-resistant TB (MDR-TB) patients had a three times greater aOR of death during treatment than non-MDR patients. American Indians, Black females, residents in long-term care facilities, US-born patients, and non-HIV-infected homeless persons aged 25-44 years each had an aOR of 2 for mortality during treatment; 86% of pulmonary patients diagnosed at death had a chest radiograph, but 34% had no sputum smear or culture reported. CONCLUSION: During 1997-2005, controlling for age, HIV remained the characteristic with the greatest aOR for TB diagnosis at death or death during TB therapy. Race/ethnicity, country of birth and homelessness further increased the adjusted odds of death. Results show possible missed opportunities for TB diagnosis prior to death. JF - International Journal of Tuberculosis and Lung Disease AU - Marks, S M AU - Magee, E AU - Robison, V AD - Centers for Disease Control and Prevention/National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention/Division of Tuberculosis Elimination, Mailstop E-10, 1600 Clifton Road, NE Atlanta, GA 30333, USA, smarks@cdc.gov Y1 - 2011/04// PY - 2011 DA - Apr 2011 SP - 465 EP - 470 PB - International Union Against Tuberculosis and Lung Disease VL - 15 IS - 4 SN - 1027-3719, 1027-3719 KW - Immunology Abstracts; Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - Mortality KW - Age KW - long-term care KW - Mycobacterium KW - Drug resistance KW - Lung diseases KW - Chest KW - Homelessness KW - tuberculosis KW - Birth KW - USA KW - Human immunodeficiency virus KW - Lung KW - Risk factors KW - Tuberculosis KW - Sputum KW - Radiography KW - Ethnic groups KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - V 22360:AIDS and HIV KW - J 02400:Human Diseases KW - R2 23060:Medical and environmental health KW - F 06910:Microorganisms & Parasites UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/867737297?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Patients+diagnosed+with+tuberculosis+at+death+or+who+died+during+therapy%3A+association+with+the+human+immunodeficiency+virus&rft.au=Marks%2C+S+M%3BMagee%2C+E%3BRobison%2C+V&rft.aulast=Marks&rft.aufirst=S&rft.date=2011-04-01&rft.volume=15&rft.issue=4&rft.spage=465&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/10.5588%2Fijtld.10.0259 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-05-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Birth; Mortality; Age; Drug resistance; Risk factors; Lung diseases; Tuberculosis; Radiography; Sputum; Chest; Ethnic groups; tuberculosis; long-term care; Lung; Human immunodeficiency virus; Homelessness; Mycobacterium; USA DO - http://dx.doi.org/10.5588/ijtld.10.0259 ER - TY - JOUR T1 - Geographic Distribution of Diagnosed Diabetes in the U.S.: A Diabetes Belt AN - 862785565; 14618578 AB - The American "stroke belt" has contributed to the study of stroke. However, U.S. geographic patterns of diabetes have not been as specifically characterized This study identifies a geographically coherent region of the U.S. where the prevalence of diagnosed diabetes is especially high, called the "diabetes belt." Methods: In 2010, data from the 2007 and 2008 Behavioral Risk Factor Surveillance System were combined with county-level diagnosed diabetes prevalence estimates. Counties in close proximity with an estimated prevalence of diagnosed diabetes >=11.0% were considered to define the diabetes belt. Prevalence of risk factors in the diabetes belt was compared to that in the rest of the U.S. The fraction of the excess risk associated with living in the diabetes belt associated with selected risk factors, both modifiable (sedentary lifestyle, obesity) and nonmodifiable (age, gender, race/ethnicity, education), was calculated. Results: A diabetes belt consisting of 644 counties in 15 mostly southern states was identified. People in the diabetes belt were more likely to be non-Hispanic African-American, lead a sedentary lifestyle, and be obese than in the rest of the U.S. Thirty percent of the excess risk was associated with modifiable risk factors, and 37% with nonmodifiable factors. Conclusions: Nearly one third of the difference in diabetes prevalence between the diabetes belt and the rest of the U.S. is associated with sedentary lifestyle and obesity. Culturally appropriate interventions aimed at decreasing obesity and sedentary lifestyle in counties within the diabetes belt should be considered. JF - American Journal of Preventive Medicine AU - Barker, Lawrence E AU - Kirtland, Karen A AU - Gregg, Edward W AU - Ma, Linda SGeiss AU - Thompson, Theodore J AD - CDC, Atlanta, Georgia, lsb8@cdc.gov Y1 - 2011/04// PY - 2011 DA - Apr 2011 SP - 434 EP - 439 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 40 IS - 4 SN - 0749-3797, 0749-3797 KW - Health & Safety Science Abstracts; Risk Abstracts KW - Risk assessment KW - Obesity KW - Age KW - Stroke KW - obesity KW - Intervention KW - Diabetes mellitus KW - stroke KW - USA KW - Education KW - diabetes mellitus KW - intervention KW - Gender KW - Ethnic groups KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/862785565?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Geographic+Distribution+of+Diagnosed+Diabetes+in+the+U.S.%3A+A+Diabetes+Belt&rft.au=Barker%2C+Lawrence+E%3BKirtland%2C+Karen+A%3BGregg%2C+Edward+W%3BMa%2C+Linda+SGeiss%3BThompson%2C+Theodore+J&rft.aulast=Barker&rft.aufirst=Lawrence&rft.date=2011-04-01&rft.volume=40&rft.issue=4&rft.spage=434&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2010.12.019 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-04-01 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - Risk assessment; Obesity; Age; Stroke; obesity; Intervention; Diabetes mellitus; stroke; diabetes mellitus; Education; intervention; Gender; Ethnic groups; USA DO - http://dx.doi.org/10.1016/j.amepre.2010.12.019 ER - TY - JOUR T1 - Male circumcision as an HIV prevention intervention in the U.S.: Influence of health care providers and potential for risk compensation AN - 862784913; 14614302 JF - Preventive Medicine AU - Gust, Deborah A AU - Kretsinger, Katrina AU - Pals, Sherri L AU - Gaul, Zaneta J AU - Hefflefinger, James D AU - Begley, Elin B AU - Chen, Robert T AU - Kilmarx, Peter H AD - Division of HIV/AIDS Prevention, National Center for HIV /AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA, dgust@cdc.gov Y1 - 2011/04// PY - 2011 DA - Apr 2011 SP - 270 EP - 273 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 52 IS - 3-4 SN - 0091-7435, 0091-7435 KW - Risk Abstracts KW - USA KW - Health care KW - Human immunodeficiency virus KW - intervention KW - prevention KW - males KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/862784913?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Preventive+Medicine&rft.atitle=Male+circumcision+as+an+HIV+prevention+intervention+in+the+U.S.%3A+Influence+of+health+care+providers+and+potential+for+risk+compensation&rft.au=Gust%2C+Deborah+A%3BKretsinger%2C+Katrina%3BPals%2C+Sherri+L%3BGaul%2C+Zaneta+J%3BHefflefinger%2C+James+D%3BBegley%2C+Elin+B%3BChen%2C+Robert+T%3BKilmarx%2C+Peter+H&rft.aulast=Gust&rft.aufirst=Deborah&rft.date=2011-04-01&rft.volume=52&rft.issue=3-4&rft.spage=270&rft.isbn=&rft.btitle=&rft.title=Preventive+Medicine&rft.issn=00917435&rft_id=info:doi/10.1016%2Fj.ypmed.2011.01.015 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-04-01 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - Health care; Human immunodeficiency virus; intervention; prevention; males; USA DO - http://dx.doi.org/10.1016/j.ypmed.2011.01.015 ER - TY - JOUR T1 - Trends in Human Immunodeficiency Virus- and Sexually Transmitted Disease-Related Risk Behaviors Among U.S. High School Students, 1991-2009 AN - 862784427; 14618577 AB - People who engage in unprotected sexual intercourse or use injection drugs are at increased risk for HIV infection and sexually transmitted diseases (STDs). Monitoring changes in behaviors over time can provide information about the effectiveness of new policies and programs To measure trends in HIV- and STD-related risk behaviors among high school students in the U.S. during 1991-2009. Methods: Nationally representative data from the 1991-2009 biennial national Youth Risk Behavior Surveys were analyzed to describe trends in HIV- and STD-related risk behaviors. For each cross-sectional national survey, students completed anonymous, self-administered questionnaires assessing risk behavior participation. This study was approved by the CDC IRB, and parental permission was obtained. To assess the significance of time trends for each behavior, logistic regression analyses were conducted that controlled for gender, grade, and race/ethnicity and simultaneously assessed linear and quadratic effects. Data were analyzed in 2010. Results: During 1991-2009, decreases were observed in the percentage of U.S. high school students who ever had sexual intercourse, had multiple sex partners, and who were currently sexually active. The prevalence of condom use increased during 1991-2003 and then leveled off during 2003-2009. However, these changes in risk behaviors were not observed in some gender and racial/ethnic subgroups. Conclusions: Additional efforts to reduce HIV- and STD-related risk behaviors, particularly among black and Hispanic students, must be implemented to decrease rates of HIV infection and STDs. JF - American Journal of Preventive Medicine AU - Eaton, Danice K AU - Lowry, Richard AU - Brener, Nancy D AU - Kann, Laura AU - Romero, Lisa AU - Wechsler, Howell AD - Division of Adolescent and School Health, National Center for Chronic Disease Prevention and Health Promotion, CDC, Atlanta, Georgia, Deaton@cdc.gov Y1 - 2011/04// PY - 2011 DA - Apr 2011 SP - 427 EP - 433 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 40 IS - 4 SN - 0749-3797, 0749-3797 KW - Immunology Abstracts; Virology & AIDS Abstracts; Health & Safety Science Abstracts; Risk Abstracts KW - sexual behavior KW - Inventories KW - Data processing KW - Sexually-transmitted diseases KW - Immunodeficiency KW - Infection KW - Condoms KW - USA KW - Behavior KW - Human immunodeficiency virus KW - Risk factors KW - Gender KW - infection KW - condoms KW - Regression analysis KW - Drugs KW - Sexual intercourse KW - sexually transmitted diseases KW - Adolescents KW - Races KW - Ethnic groups KW - Sex KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health KW - F 06910:Microorganisms & Parasites KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/862784427?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Trends+in+Human+Immunodeficiency+Virus-+and+Sexually+Transmitted+Disease-Related+Risk+Behaviors+Among+U.S.+High+School+Students%2C+1991-2009&rft.au=Eaton%2C+Danice+K%3BLowry%2C+Richard%3BBrener%2C+Nancy+D%3BKann%2C+Laura%3BRomero%2C+Lisa%3BWechsler%2C+Howell&rft.aulast=Eaton&rft.aufirst=Danice&rft.date=2011-04-01&rft.volume=40&rft.issue=4&rft.spage=427&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2010.12.010 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-04-01 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - Inventories; Data processing; Sexually-transmitted diseases; Immunodeficiency; Infection; Condoms; Risk factors; Regression analysis; Sexual intercourse; Drugs; Ethnic groups; Races; Sex; sexual behavior; Behavior; Human immunodeficiency virus; Gender; condoms; infection; Adolescents; sexually transmitted diseases; USA DO - http://dx.doi.org/10.1016/j.amepre.2010.12.010 ER - TY - JOUR T1 - Serum alpha -Carotene Concentrations and Risk of Death Among US Adults: The Third National Health and Nutrition Examination Survey Follow-up Study AN - 1032902664; 14592200 AB - BACKGROUND: Much research has been conducted relating total carotenoids-and beta -carotene in particular-to risk of cancer and cardiovascular disease (CVD). Limited data are emerging to implicate the important role of alpha -carotene in the development of CVD or cancer. METHODS: We assessed the direct relationship between alpha -carotene concentrations and risk of death among 15 318 US adults 20 years and older who participated in the Third National Health and Nutrition Examination Survey Follow-up Study. We used Cox proportional hazard regression analyses to estimate the relative risk for death from all causes and selected causes associated with serum alpha -carotene concentrations. RESULTS: Compared with participants with serum alpha -carotene concentrations of 0 to 1 mu g/dL (to convert to micromoles per liter, multiply by 0.01863), those with higher serum levels had a lower risk of death from all causes (P < .001 for linear trend): the relative risk for death was 0.77 (95% confidence interval, 0.68-0.87) among those with alpha -carotene concentrations of 2 to 3 mu g/dL, 0.73 (0.65-0.83) among those with concentrations of 4 to 5 mu g/dL, 0.66 (0.55-0.79) among those with concentrations of 6 to 8 mu g/dL, and 0.61 (0.51-0.73) among those with concentrations of 9 mu g/dL or higher after adjustment for potential confounding variables. We also found significant associations between serum alpha -carotene concentrations and risk of death from CVD (P = .007), cancer (P = .02), and all other causes (P < .001). The association between serum alpha -carotene concentrations and risk of death from all causes was significant in most subgroups stratified by demographic characteristics, lifestyle habits, and health risk factors. CONCLUSIONS: Serum alpha -carotene concentrations were inversely associated with risk of death from all causes, CVD, cancer, and all other causes. These findings support increasing fruit and vegetable consumption as a means of preventing premature death. JF - Archives of Internal Medicine AU - Li, Chaoyang AU - Ford, Earl S AU - Zhao, Guixiang AU - Balluz, Lina S AU - Giles, Wayne H AU - Liu, Simin AD - Author Affiliations: Division of Behavioral Surveillance, Office of Surveillance, Epidemiology, and Laboratory Services (Drs Li and Balluz), and Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion (Drs Ford, Zhao, and Giles), Centers for Disease Control and Prevention, Atlanta, Georgia Y1 - 2011/03/28/ PY - 2011 DA - 2011 Mar 28 SP - 507 EP - 515 PB - American Medical Association, 515 N. State St. Chicago IL 60610 USA VL - 171 IS - 6 SN - 0003-9926, 0003-9926 KW - Health & Safety Science Abstracts KW - Cancer KW - Cardiovascular diseases KW - Demography KW - Fruits KW - Health risks KW - Mortality KW - Nutrition KW - Risk assessment KW - USA KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1032902664?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Archives+of+Internal+Medicine&rft.atitle=Serum+alpha+-Carotene+Concentrations+and+Risk+of+Death+Among+US+Adults%3A+The+Third+National+Health+and+Nutrition+Examination+Survey+Follow-up+Study&rft.au=Li%2C+Chaoyang%3BFord%2C+Earl+S%3BZhao%2C+Guixiang%3BBalluz%2C+Lina+S%3BGiles%2C+Wayne+H%3BLiu%2C+Simin&rft.aulast=Li&rft.aufirst=Chaoyang&rft.date=2011-03-28&rft.volume=171&rft.issue=6&rft.spage=507&rft.isbn=&rft.btitle=&rft.title=Archives+of+Internal+Medicine&rft.issn=00039926&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-08-01 N1 - Last updated - 2012-08-24 N1 - SubjectsTermNotLitGenreText - Demography; Risk assessment; Health risks; Fruits; Mortality; Cardiovascular diseases; Nutrition; Cancer; USA ER - TY - JOUR T1 - Quantitative mass spectrometry for bacterial protein toxins--a sensitive, specific, high-throughput tool for detection and diagnosis. AN - 857290630; 21403598 AB - Matrix-assisted laser-desorption time-of-flight (MALDI-TOF) mass spectrometry (MS) is a valuable high-throughput tool for peptide analysis. Liquid chromatography electrospray ionization (LC-ESI) tandem-MS provides sensitive and specific quantification of small molecules and peptides. The high analytic power of MS coupled with high-specificity substrates is ideally suited for detection and quantification of bacterial enzymatic activities. As specific examples of the MS applications in disease diagnosis and select agent detection, we describe recent advances in the analyses of two high profile protein toxin groups, the Bacillus anthracis toxins and the Clostridium botulinum neurotoxins. The two binary toxins produced by B. anthracis consist of protective antigen (PA) which combines with lethal factor (LF) and edema factor (EF), forming lethal toxin and edema toxin respectively. LF is a zinc-dependent endoprotease which hydrolyzes specific proteins involved in inflammation and immunity. EF is an adenylyl cyclase which converts ATP to cyclic-AMP. Toxin-specific enzyme activity for a strategically designed substrate, amplifies reaction products which are detected by MALDI-TOF-MS and LC-ESI-MS/MS. Pre-concentration/purification with toxin specific monoclonal antibodies provides additional specificity. These combined technologies have achieved high specificity, ultrasensitive detection and quantification of the anthrax toxins. We also describe potential applications to diseases of high public health impact, including Clostridium difficile glucosylating toxins and the Bordetella pertussis adenylyl cyclase. JF - Molecules (Basel, Switzerland) AU - Boyer, Anne E AU - Gallegos-Candela, Maribel AU - Lins, Renato C AU - Kuklenyik, Zsuzsanna AU - Woolfitt, Adrian AU - Moura, Hercules AU - Kalb, Suzanne AU - Quinn, Conrad P AU - Barr, John R AD - Centers for Disease Control and Prevention, 4770 Buford Hwy, NE, Atlanta, GA 30341, USA. jbarr@cdc.gov Y1 - 2011/03/14/ PY - 2011 DA - 2011 Mar 14 SP - 2391 EP - 2413 VL - 16 IS - 3 KW - Bacterial Proteins KW - 0 KW - Index Medicus KW - Molecular Sequence Data KW - Amino Acid Sequence KW - Sequence Homology, Amino Acid KW - Limit of Detection KW - Bacillus anthracis -- chemistry KW - Tandem Mass Spectrometry -- methods KW - Bacterial Proteins -- analysis KW - Spectrometry, Mass, Electrospray Ionization -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/857290630?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Molecules+%28Basel%2C+Switzerland%29&rft.atitle=Quantitative+mass+spectrometry+for+bacterial+protein+toxins--a+sensitive%2C+specific%2C+high-throughput+tool+for+detection+and+diagnosis.&rft.au=Boyer%2C+Anne+E%3BGallegos-Candela%2C+Maribel%3BLins%2C+Renato+C%3BKuklenyik%2C+Zsuzsanna%3BWoolfitt%2C+Adrian%3BMoura%2C+Hercules%3BKalb%2C+Suzanne%3BQuinn%2C+Conrad+P%3BBarr%2C+John+R&rft.aulast=Boyer&rft.aufirst=Anne&rft.date=2011-03-14&rft.volume=16&rft.issue=3&rft.spage=2391&rft.isbn=&rft.btitle=&rft.title=Molecules+%28Basel%2C+Switzerland%29&rft.issn=1420-3049&rft_id=info:doi/10.3390%2Fmolecules16032391 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-06-16 N1 - Date created - 2011-03-15 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.3390/molecules16032391 ER - TY - JOUR T1 - Effectiveness of Ignition Interlocks for Preventing Alcohol-Impaired Driving and Alcohol-Related Crashes: A Community Guide Systematic Review AN - 954634026; 14444123 AB - A systematic review of the literature to assess the effectiveness of ignition interlocks for reducing alcohol-impaired driving and alcohol-related crashes was conducted for the Guide to Community Preventive Services (Community Guide). Because one of the primary research issues of interest - the degree to which the installation of interlocks in offenders' vehicles reduces alcohol-impaired driving in comparison to alternative sanctions (primarily license suspension) - was addressed by a 2004 systematic review conducted for the Cochrane Collaboration, the current review incorporates that previous work and extends it to include more recent literature and crash outcomes. The body of evidence evaluated includes the 11 studies from the prior review, plus four more recent studies published through December 2007. The installation of ignition interlocks was associated consistently with large reductions in re-arrest rates for alcohol-impaired driving within both the earlier and later bodies of evidence. Following removal of interlocks, re-arrest rates reverted to levels similar to those for comparison groups. The limited available evidence from three studies that evaluated crash rates suggests that alcohol-related crashes decrease while interlocks are installed in vehicles. According to Community Guide rules of evidence, these findings provide strong evidence that interlocks, while they are in use in offenders' vehicles, are effective in reducing re-arrest rates. However, the potential for interlock programs to reduce alcohol-related crashes is currently limited by the small proportion of offenders who participate in the programs and the lack of a persistent beneficial effect once the interlock is removed. Suggestions for facilitating more widespread and sustained use of ignition interlocks are provided. JF - American Journal of Preventive Medicine AU - Elder, Randy W AU - Voas, Robert AU - Beirness, Doug AU - Shults, Ruth A AU - Sleet, David A AU - Nichols, James L AU - Compton, Richard AD - Division of Community Preventive Services, Epidemiology and Analysis Program Office, CDC, Atlanta, Georgia, rfe3@cdc.gov Y1 - 2011/03// PY - 2011 DA - March 2011 SP - 362 EP - 376 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 40 IS - 3 SN - 0749-3797, 0749-3797 KW - Health & Safety Science Abstracts KW - Alcohol KW - Accidents KW - Reviews KW - recidivism KW - traffic safety KW - H 2000:Transportation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/954634026?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Effectiveness+of+Ignition+Interlocks+for+Preventing+Alcohol-Impaired+Driving+and+Alcohol-Related+Crashes%3A+A+Community+Guide+Systematic+Review&rft.au=Elder%2C+Randy+W%3BVoas%2C+Robert%3BBeirness%2C+Doug%3BShults%2C+Ruth+A%3BSleet%2C+David+A%3BNichols%2C+James+L%3BCompton%2C+Richard&rft.aulast=Elder&rft.aufirst=Randy&rft.date=2011-03-01&rft.volume=40&rft.issue=3&rft.spage=362&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2010.11.012 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Alcohol; Accidents; Reviews; recidivism; traffic safety DO - http://dx.doi.org/10.1016/j.amepre.2010.11.012 ER - TY - JOUR T1 - Detection of Borrelia burgdorferi DNA in Tick Feces Provides Evidence for Organism Shedding During Vector Feeding AN - 918059298; 16154991 AB - Borrelia burgdorferi, the bacterium that causes Lyme disease, is transmitted to a susceptible host by Ixodes spp. tick bites. However, there is uncertainty whether B. burgdorferi are shed from ticks by the fecal route. In this study, B. burgdorferi-infected ticks were fed on mice while confined to a certain area of the skin by a capsule. During and after feeding, tick feces were collected and placed in Barbour-Stoenner-Kelley (BSK)-II media for cultivation and in sterile water for polymerase chain reaction (PCR) analysis. Although none of the tested samples were culture positive for B. burgdorferi, all but one of the fecal DNA samples from infected ticks were PCR positive. These results indicated that B. burgdorferi were shed from feeding ticks during defecation and suggest that the spirochetes did not remain viable once exposed to the outside environment. This finding has important ramifications for investigators interpreting B. burgdorferi-specific PCR results when conducting tick transmission experiments. JF - Vector Borne and Zoonotic Diseases AU - Patton, T G AU - Dietrich, G AU - Gilmore, RD Jr AD - Microbiology and Pathogenesis Activity, Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, 3150 Rampart Road Fort Collins, CO 80521, USA, rbg9@cdc.gov Y1 - 2011/03// PY - 2011 DA - Mar 2011 SP - 197 EP - 200 VL - 11 IS - 3 SN - 1530-3667, 1530-3667 KW - Biochemistry Abstracts 2: Nucleic Acids; Entomology Abstracts; Microbiology Abstracts B: Bacteriology KW - Ixodes KW - Feeding KW - Skin KW - Borrelia burgdorferi KW - Defecation KW - Bites KW - Ixodidae KW - Vectors KW - Disease transmission KW - Spirochetes KW - Polymerase chain reaction KW - Feces KW - Media (culture) KW - Lyme disease KW - J 02410:Animal Diseases KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - N 14835:Protein-Nucleic Acids Association UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/918059298?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vector+Borne+and+Zoonotic+Diseases&rft.atitle=Detection+of+Borrelia+burgdorferi+DNA+in+Tick+Feces+Provides+Evidence+for+Organism+Shedding+During+Vector+Feeding&rft.au=Patton%2C+T+G%3BDietrich%2C+G%3BGilmore%2C+RD+Jr&rft.aulast=Patton&rft.aufirst=T&rft.date=2011-03-01&rft.volume=11&rft.issue=3&rft.spage=197&rft.isbn=&rft.btitle=&rft.title=Vector+Borne+and+Zoonotic+Diseases&rft.issn=15303667&rft_id=info:doi/10.1089%2Fvbz.2010.0149 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-01-01 N1 - Last updated - 2014-05-15 N1 - SubjectsTermNotLitGenreText - Spirochetes; Feeding; Skin; Bites; Defecation; Vectors; Polymerase chain reaction; Feces; Media (culture); Disease transmission; Lyme disease; Ixodes; Borrelia burgdorferi; Ixodidae DO - http://dx.doi.org/10.1089/vbz.2010.0149 ER - TY - JOUR T1 - Persistent Infection or Successive Reinfection of Deer Mice with Bartonella vinsonii subsp. arupensis AN - 904472090; 14403465 AB - Bartonella infections are common in rodents. From 1994 to 2006, longitudinal studies of a rodent community, consisting mainly of deer mice (Peromyscus maniculatus), were conducted in southwestern Colorado to study hantaviruses. Blood samples from deer mice captured one or more times during the period 2003 to 2006 (n = 737) were selected to study bartonellae in deer mice. Bartonellae were found to be widely distributed in that population, with an overall prevalence of 82.4% (607/737 mice). No correlation was found between bartonella prevalence and deer mouse weight or sex. Persistent or successive infections with bartonellae were observed in deer mice captured repeatedly, with a prevalence of 83.9% (297/354), and the infection appeared to last for more than 1 year in some of them. Persistent infection with bartonellae may explain the high prevalence of these bacteria in deer mice at this site and, perhaps, elsewhere. Genetic analysis demonstrated that deer mouse-borne bartonella isolates at this site belong to the same species, B. vinsonii subsp. arupensis, demonstrating a specific relationship between B. vinsonii subsp. arupensis and deer mice. JF - Applied and Environmental Microbiology AU - Bai, Ying AU - Calisher, Charles H AU - Kosoy, Michael Y AU - Root, JJeffrey AU - Doty, Jeffrey B AD - Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, U.S. Centers for Disease Control and Prevention, Fort Collins, Colorado 80521. Arthropod-Borne and Infectious Diseases Laboratory, Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado 80523 Y1 - 2011/03/01/ PY - 2011 DA - 2011 Mar 01 SP - 1728 EP - 1731 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 77 IS - 5 SN - 0099-2240, 0099-2240 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Bartonella KW - Bartonella vinsonii KW - Genetic analysis KW - Peromyscus maniculatus KW - Persistent infection KW - Sex KW - J 02410:Animal Diseases KW - A 01450:Environmental Pollution & Waste Treatment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/904472090?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Persistent+Infection+or+Successive+Reinfection+of+Deer+Mice+with+Bartonella+vinsonii+subsp.+arupensis&rft.au=Bai%2C+Ying%3BCalisher%2C+Charles+H%3BKosoy%2C+Michael+Y%3BRoot%2C+JJeffrey%3BDoty%2C+Jeffrey+B&rft.aulast=Bai&rft.aufirst=Ying&rft.date=2011-03-01&rft.volume=77&rft.issue=5&rft.spage=1728&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2013-07-15 N1 - SubjectsTermNotLitGenreText - Genetic analysis; Persistent infection; Sex; Bartonella; Bartonella vinsonii; Peromyscus maniculatus ER - TY - JOUR T1 - Health disparities in low-income families with infants and toddlers: Needs and challenges related to disability AN - 896188539; 2011-126224 AB - This study examines disparities in health status, health care utilization, insurance coverage and satisfaction in US low-income parents of infants and toddlers with disabilities compared to low-income parents of children without disabilities. The Early Head Start Research and Evaluation Project is a longitudinal study involving 2087 families in 17 communities across the United States. Families completed interviews at enrollment and at 7, 16, and 28 months after enrollment. Descriptive analyses were conducted to characterize children's status in terms of health, health care use, and insurance coverage. Children with disabilities were more likely to experience poor health and to use more health care services. Parents of children with disabilities were more likely to report that medical care was inadequate. Hispanic children were less likely to experience excellent health. Hispanic parents were less likely to have health insurance or to report that their medical care was adequate. Low-income parents of young children with disabilities perceived their children as less healthy, more vulnerable and needing more health services. This study demonstrates the importance of providing accessible, culturally-competent services to this vulnerable population. [Reprinted by permission of Sage Publications Ltd., copyright holder.] JF - Journal of Child Health Care AU - Swanson, Mark E AU - Wall, Shavaun AU - Kisker, Ellen AU - Peterson, Carla AD - Centers for Disease Control and Prevention, USA meswanson@cdc.gov Y1 - 2011/03// PY - 2011 DA - March 2011 SP - 25 EP - 38 PB - Sage Publications, London UK VL - 15 IS - 1 SN - 1367-4935, 1367-4935 KW - Population groups, population policy, and demographics - Children and youth KW - Social conditions and policy - Marriage and family life KW - Health conditions and policy - Medicine and health care KW - Population groups, population policy, and demographics - National, ethnic, and minority groups KW - Business and service sector - Insurance KW - Health conditions and policy - Health and health policy KW - child health disability inequalities in health KW - United States KW - Health insurance KW - Medical service KW - Parents KW - Children KW - Child health KW - Hispanics KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/896188539?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Child+Health+Care&rft.atitle=Health+disparities+in+low-income+families+with+infants+and+toddlers%3A+Needs+and+challenges+related+to+disability&rft.au=Swanson%2C+Mark+E%3BWall%2C+Shavaun%3BKisker%2C+Ellen%3BPeterson%2C+Carla&rft.aulast=Swanson&rft.aufirst=Mark&rft.date=2011-03-01&rft.volume=15&rft.issue=1&rft.spage=25&rft.isbn=&rft.btitle=&rft.title=Journal+of+Child+Health+Care&rft.issn=13674935&rft_id=info:doi/10.1177%2F1367493510387951 LA - English DB - PAIS Index N1 - Date revised - 2011-10-03 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Children; Parents; Medical service; Hispanics; United States; Health insurance; Child health DO - http://dx.doi.org/10.1177/1367493510387951 ER - TY - JOUR T1 - Sensitivity of Birth Certificate Reports of Birth Defects in Atlanta, 1995-2005: Effects of Maternal, Infant, and Hospital Characteristics AN - 881466067; 2011-104547 AB - We assessed variations in the sensitivity of birth defect diagnoses derived from birth certificate data by maternal, infant, and hospital characteristics. We compared birth certificate data for 1995-2005 births in Atlanta with data from the Metropolitan Atlanta Congenital Defects Program (MACDP). We calculated the sensitivity of birth certificates for reporting defects often discernable at birth (e.g., anencephaly, spina bifida, cleft lip, clubfoot, Down syndrome, and rectal atresia or stenosis). We used multivariable logistic regression models to examine associations with sociodemographic and hospital factors. The overall sensitivity of birth certificates was 23% and ranged from 7% for rectal atresia/stenosis to 69% for anencephaly. Non-Hispanic black maternal race/ethnicity, less than a high school education, and preterm birth were independently associated with a lower probability of a birth defect diagnosis being reported on a birth certificate. Sensitivity also was lower for hospitals with > 1,000 births per year. The underreporting of birth defects on birth certificates is influenced by sociodemographic and hospital characteristics. Interpretation of birth defects prevalence estimates derived from birth certificate reports should take these issues into account. Adapted from the source document. JF - Public Health Reports AU - Boulet, Sheree L AU - Shin, Mikyong AU - Kirby, Russell S AU - Goodman, David AU - Correa, Adolfo AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 1600 Clifton Rd., MS-DO2, Atlanta, GA 30333, tel. 404-639-4032, fax 404-639-3060 E-mail: sboulet@cdc.gov Y1 - 2011/03// PY - 2011 DA - March 2011 SP - 186 EP - 194 PB - Oxford University Press, UK VL - 126 IS - 2 SN - 0033-3549, 0033-3549 KW - Law and ethics - Family law KW - Health conditions and policy - Hospitals and other health care facilities KW - Health conditions and policy - Diseases and disorders KW - Population groups, population policy, and demographics - Demography and census KW - Population groups, population policy, and demographics - Children and youth KW - Education and education policy - Schools KW - Education and education policy - Education KW - Population groups, population policy, and demographics - National, ethnic, and minority groups KW - Social conditions and policy - Associations and meetings KW - Birth defects KW - Education KW - High schools KW - Birth certificates KW - Blacks KW - Associations KW - Infants KW - Hospitals KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/881466067?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Public+Health+Reports&rft.atitle=Sensitivity+of+Birth+Certificate+Reports+of+Birth+Defects+in+Atlanta%2C+1995-2005%3A+Effects+of+Maternal%2C+Infant%2C+and+Hospital+Characteristics&rft.au=Boulet%2C+Sheree+L%3BShin%2C+Mikyong%3BKirby%2C+Russell+S%3BGoodman%2C+David%3BCorrea%2C+Adolfo&rft.aulast=Boulet&rft.aufirst=Sheree&rft.date=2011-03-01&rft.volume=126&rft.issue=2&rft.spage=186&rft.isbn=&rft.btitle=&rft.title=Public+Health+Reports&rft.issn=00333549&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2011-08-04 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Birth certificates; Hospitals; Birth defects; Infants; High schools; Education; Blacks; Associations ER - TY - JOUR T1 - Medical expenditures of children in the United States with fetal alcohol syndrome AN - 867747349; 14630109 AB - This paper calculates the medical expenditures for pediatric Medicaid enrollees with fetal alcohol syndrome (FAS), those with and those without reported intellectual disability (ID). The pediatric portion of the MarketScan registered Medicaid Multi-State databases for the years 2003-2005 was used. Children with FAS were identified based on International Classification of Diseases, Ninth Revision, Clinical Modification codes. Children without FAS formed the comparison group. Annual mean, median, and 95th percentile total expenditures were calculated for those continuously enrolled during 2005. Children with FAS incurred annual mean medical expenditures that were nine times as high as those of children without FAS during 2005 ($16,782 vs. $1,859). ID more commonly was listed as a medical diagnosis among children with FAS than among children in the comparison group (12% vs. 0.5%), and mean expenditures of children with FAS and ID were 2.8 times those of children with FAS but without reported ID. Children with FAS incurred higher medical expenditures compared with children without FAS. A subset of children with FAS who had ID sufficiently serious to be recorded in medical records increased those expenditures still further. Our estimate of mean expenditures for children with FAS was several times higher than previous estimates in the United States. JF - Neurotoxicology and Teratology AU - Amendah, Djesika D AU - Grosse, Scott D AU - Bertrand, Jacquelyn AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Mailstop M-64, Atlanta, GA 30333, United States, damendah@gmail.com Y1 - 2011/03// PY - 2011 DA - Mar 2011 PB - Elsevier B.V., Box 882 New York NY 10159 USA, [mailto:usinfo-f@elsevier.com] VL - 33 IS - 2 SN - 0892-0362, 0892-0362 KW - Toxicology Abstracts; CSA Neurosciences Abstracts KW - Databases KW - Classification KW - Pediatrics KW - medical records KW - Fetal alcohol syndrome KW - Mental retardation KW - Children KW - X 24380:Social Poisons & Drug Abuse KW - N3 11028:Neuropharmacology & toxicology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/867747349?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Neurotoxicology+and+Teratology&rft.atitle=Medical+expenditures+of+children+in+the+United+States+with+fetal+alcohol+syndrome&rft.au=Amendah%2C+Djesika+D%3BGrosse%2C+Scott+D%3BBertrand%2C+Jacquelyn&rft.aulast=Amendah&rft.aufirst=Djesika&rft.date=2011-03-01&rft.volume=33&rft.issue=2&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Neurotoxicology+and+Teratology&rft.issn=08920362&rft_id=info:doi/10.1016%2Fj.ntt.2010.10.008 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-05-01 N1 - Last updated - 2014-07-10 N1 - SubjectsTermNotLitGenreText - Databases; Classification; medical records; Pediatrics; Fetal alcohol syndrome; Mental retardation; Children DO - http://dx.doi.org/10.1016/j.ntt.2010.10.008 ER - TY - JOUR T1 - Genetic diversity of a Korean echovirus 5 isolate and response of the strain to five antiviral drugs AN - 872138625; 14607730 AB - An outbreak of echovirus 5 (ECV 5) occurred in Korea in 2006, marking the first time this virus had been identified in the country since enterovirus surveillance began in 1993. Using a sample isolated from a young male patient with aseptic meningitis, we performed sequencing of the Korean ECV 5 strain and compared it with a prototype strain (Noyce). At the nucleotide level, the P1 region (85.3%) had the highest identity value; at the amino acid level, the P3 region (98.0%) had the highest identity value. The two strains shared all cleavage sites, with the exception of the VP1/2A site, which was TY/GA in the Noyce strain but TR/GA in the Korean ECV 5 isolate. In Vero cells infected with the Korean ECV 5 isolate, no cytotoxicity was observed in the presence of azidothymidine, acyclovir, amantadine, lamivudine, or ribavirin, when the drugs were administered at a CC50 value >100 I14g/mL. Of the five drugs, only amantadine (IC50: 1 A- 0.42 I14g/mL, TI: 100) and ribavirin (IC50: 22 A- 1.36 I14g/mL, TI: 4.55) had any antiviral activity against the Korean ECV 5 isolate. JF - Virology Journal AU - Park, Kwisung AU - Song, Jaehyoung AU - Baek, Kyoungah AU - Lee, Changgyun AU - Kim, Donguk AU - Cho, SamHyun AU - Park, JoonSoo AU - Choi, YoungJin AU - Kang, Byunghak AU - Choi, Hwajung AU - Cheon, Doo-Sung AD - Department of Enteric and Hepatitis Viruses, National Institute of Health, Korea Center for Disease Control and Prevention, Seoul, Korea Y1 - 2011/02/24/ PY - 2011 DA - 2011 Feb 24 SP - 79 PB - BioMed Central Ltd., Middlesex House London W1T 4LB UK VL - 8 KW - Genetics Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology; Virology & AIDS Abstracts KW - Amantadine KW - Amino acids KW - Antiviral activity KW - Antiviral agents KW - Aseptic meningitis KW - Cytotoxicity KW - Genetic diversity KW - Lamivudine KW - Nucleotides KW - Ribavirin KW - VP1 protein KW - Vero cells KW - acyclovir KW - Enterovirus KW - Echovirus KW - A 01340:Antibiotics & Antimicrobials KW - G 07750:Ecological & Population Genetics KW - V 22340:Antiviral Agents UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/872138625?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Virology+Journal&rft.atitle=Genetic+diversity+of+a+Korean+echovirus+5+isolate+and+response+of+the+strain+to+five+antiviral+drugs&rft.au=Park%2C+Kwisung%3BSong%2C+Jaehyoung%3BBaek%2C+Kyoungah%3BLee%2C+Changgyun%3BKim%2C+Donguk%3BCho%2C+SamHyun%3BPark%2C+JoonSoo%3BChoi%2C+YoungJin%3BKang%2C+Byunghak%3BChoi%2C+Hwajung%3BCheon%2C+Doo-Sung&rft.aulast=Park&rft.aufirst=Kwisung&rft.date=2011-02-24&rft.volume=8&rft.issue=&rft.spage=79&rft.isbn=&rft.btitle=&rft.title=Virology+Journal&rft.issn=1743-422X&rft_id=info:doi/10.1186%2F1743-422X-8-79 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-06-01 N1 - Last updated - 2012-06-29 N1 - SubjectsTermNotLitGenreText - Aseptic meningitis; Amino acids; Vero cells; Ribavirin; Lamivudine; Genetic diversity; acyclovir; Antiviral activity; Nucleotides; Cytotoxicity; Antiviral agents; VP1 protein; Amantadine; Enterovirus; Echovirus DO - http://dx.doi.org/10.1186/1743-422X-8-79 ER - TY - JOUR T1 - Defying birth defects through diet? AN - 926888160; 16344164 AB - The risk of certain birth defects can be modified by maternal diet. A high-fat maternal mouse diet has recently been reported to substantially increase the penetrance of birth defects known to be associated with a deficiency of transcription factor Cited2 as well as induce cleft palate. These effects were associated with a more than twofold reduction in embryonic expression of Pitx2c. This investigation suggests the need to further explore this provocative gene-diet interaction in human studies. JF - Genome Medicine AU - Crider, Krista S AU - Bailey, Lynn B AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 1600 Clifton Road, MS E-86, Atlanta, GA 30333, USA, kvc3@cdc.gov Y1 - 2011/02/09/ PY - 2011 DA - 2011 Feb 09 SP - 9 PB - BioMed Central Ltd., Middlesex House London W1T 4LB United Kingdom VL - 3 IS - 2 KW - Biotechnology and Bioengineering Abstracts; Genetics Abstracts KW - Diets KW - Transcription factors KW - Congenital defects KW - Embryos KW - Cleft lip/palate KW - G 07870:Mammals KW - W 30965:Miscellaneous, Reviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/926888160?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Genome+Medicine&rft.atitle=Defying+birth+defects+through+diet%3F&rft.au=Crider%2C+Krista+S%3BBailey%2C+Lynn+B&rft.aulast=Crider&rft.aufirst=Krista&rft.date=2011-02-09&rft.volume=3&rft.issue=2&rft.spage=9&rft.isbn=&rft.btitle=&rft.title=Genome+Medicine&rft.issn=1756-994X&rft_id=info:doi/10.1186%2Fgm223 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2012-04-06 N1 - SubjectsTermNotLitGenreText - Diets; Transcription factors; Congenital defects; Embryos; Cleft lip/palate DO - http://dx.doi.org/10.1186/gm223 ER - TY - JOUR T1 - Multistate outbreak of Escherichia coli O157:H7 infections associated with a national fast-food chain, 2006: a study incorporating epidemiological and food source traceback results AN - 856783164; 14296872 AB - A multistate outbreak of Escherichia coli O157:H7 infections occurred in the USA in November-December 2006 in patrons of restaurant chain A. We identified 77 cases with chain A exposure in four states - Delaware, New Jersey, New York, and Pennsylvania. Fifty-one (66%) patients were hospitalized, and seven (9%) developed haemolytic uraemic syndrome; none died. In a matched analysis controlling for age in 31 cases and 55 controls, illness was associated with consumption of shredded iceberg lettuce [matched odds ratio (mOR) 8.0, 95% confidence interval (CI) 1.1-348.1] and shredded cheddar cheese (mOR 6.2, CI 1.7-33.7). Lettuce, an uncooked ingredient, was more commonly consumed (97% of patients) than cheddar cheese (84%) and a single source supplied all affected restaurants. A single source of cheese could not explain the regional distribution of outbreak cases. The outbreak highlights challenges in conducting rapid multistate investigations and the importance of incorporating epidemiological study results with other investigative findings. JF - Epidemiology and Infection AU - Sodha, S V AU - Lynch, M AU - Wannemuehler, K AU - Leeper, M AU - Malavet, M AU - Schaffzin, J AU - Chen, T AU - Langer, A AU - GLENSHAW, M AU - Hoefer, D AU - Dumas, N AU - Lind, L AU - Iwamoto, M AU - Ayers, T AU - Nguyen, T AU - Biggerstaff, M AU - Olson, C AU - Sheth, A AU - Braden, C AD - Centers for Disease Control and Prevention , Atlanta , GA , USA, ssodha@cdc.gov ssodha@cdc.gov ssodha@cdc.gov ssodha@cdc.gov ssodha@cdc.gov ssodha@cdc.gov ssodha@cdc.gov ssodha@cdc.gov ssodha@cdc.gov ssodha@cdc.gov Y1 - 2011/02// PY - 2011 DA - Feb 2011 SP - 309 EP - 316 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU UK VL - 139 IS - 2 SN - 0950-2688, 0950-2688 KW - Microbiology Abstracts B: Bacteriology KW - Cheddar cheese KW - Food sources KW - Escherichia coli KW - Infection KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/856783164?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Multistate+outbreak+of+Escherichia+coli+O157%3AH7+infections+associated+with+a+national+fast-food+chain%2C+2006%3A+a+study+incorporating+epidemiological+and+food+source+traceback+results&rft.au=Sodha%2C+S+V%3BLynch%2C+M%3BWannemuehler%2C+K%3BLeeper%2C+M%3BMalavet%2C+M%3BSchaffzin%2C+J%3BChen%2C+T%3BLanger%2C+A%3BGLENSHAW%2C+M%3BHoefer%2C+D%3BDumas%2C+N%3BLind%2C+L%3BIwamoto%2C+M%3BAyers%2C+T%3BNguyen%2C+T%3BBiggerstaff%2C+M%3BOlson%2C+C%3BSheth%2C+A%3BBraden%2C+C&rft.aulast=Sodha&rft.aufirst=S&rft.date=2011-02-01&rft.volume=139&rft.issue=2&rft.spage=309&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS0950268810000920 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-03-01 N1 - Number of references - 15 N1 - Last updated - 2013-07-26 N1 - SubjectsTermNotLitGenreText - Cheddar cheese; Food sources; Infection; Escherichia coli DO - http://dx.doi.org/10.1017/S0950268810000920 ER - TY - JOUR T1 - HIV-testing behavior among young migrant men who have sex with men (MSM) in Beijing, China AN - 850556052; 4163166 AB - Previous studies suggested a rapid increase of HIV prevalence among men who have sex with men (MSM) in China in recent years, from 0.4% in 2004 to 5.8% in 2006. However, some MSM had never been tested for HIV. In order to expand the accessibility to HIV testing, understanding HIV-testing behavior and barriers among MSM is important. Using data collected from 307 young migrant MSM (aged 18-29 years) in 2009 in Beijing, we aimed to identify psychological and structural barriers to HIV testing. MSM were recruited through peer outreach, informal social networks, Internet outreach, and venue-based outreach. Participants completed a confidential self-administered questionnaire. Results show that about 72% of MSM ever had an HIV test. Logistic regression analysis indicated that the HIV-testing behavior was associated with sexual risk behaviors (e.g., multiple sexual partners and inconsistent condom use for anal sex) and history of sexually transmitted diseases. Eighty four MSM (28%) who never had an HIV test reported that the psychological barriers mainly were perceived low risk of HIV infection and fears of being stigmatized. The structural barriers reported inconvenience of doing test and lack of confidentiality. Future HIV prevention programs should be strengthened among MSM to increase their awareness of HIV risk. Efforts are needed to increase access to quality and confidential HIV testing among MSM and reduce stigma against MSM. Reprinted by permission of Routledge, Taylor & Francis Ltd. JF - AIDS care AU - Song, Yan AU - Li, Xiaoming AU - Zhang, Liying AU - Fang, Xiaoyi AU - Lin, Xiuyun AU - Liu, Yinjie AU - Stanton, Bonita AD - Fudan University ; Wayne State University ; Beijing Normal University ; Chaoyang District Center for Disease Control and Prevention, Beijing Y1 - 2011/02// PY - 2011 DA - Feb 2011 SP - 179 EP - 186 VL - 23 IS - 2 SN - 0954-0121, 0954-0121 KW - Sociology KW - Beijing KW - Prevention KW - Medical research KW - Surveys KW - Homosexuality KW - HIV KW - Stigma KW - China KW - Sexually transmitted diseases KW - Youth KW - Migrants UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/850556052?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+care&rft.atitle=HIV-testing+behavior+among+young+migrant+men+who+have+sex+with+men+%28MSM%29+in+Beijing%2C+China&rft.au=Song%2C+Yan%3BLi%2C+Xiaoming%3BZhang%2C+Liying%3BFang%2C+Xiaoyi%3BLin%2C+Xiuyun%3BLiu%2C+Yinjie%3BStanton%2C+Bonita&rft.aulast=Song&rft.aufirst=Yan&rft.date=2011-02-01&rft.volume=23&rft.issue=2&rft.spage=179&rft.isbn=&rft.btitle=&rft.title=AIDS+care&rft.issn=09540121&rft_id=info:doi/10.1080%2F09540121.2010.487088 LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 12258 11762 11859 11856; 5703 3617 6220; 8037; 13779 652 5676 646 6091; 5969 11579 11538; 11581 3617 6220; 10072; 7886 10902; 12429; 93 116 30 DO - http://dx.doi.org/10.1080/09540121.2010.487088 ER - TY - JOUR T1 - Occupational lung cancer in US women, 1984-1998. AN - 847278896; 21259296 AB - Lung cancer is the leading cause of cancer death in US women, accounting for 72,130 deaths in 2006. In addition to smoking cessation, further reduction of the burden of lung cancer mortality can be made by preventing exposure to occupational lung carcinogens. Data for occupational exposures and health outcomes of US working women are limited. Population-based mortality data for 4,570,711 women who died between 1984 and 1998 in 27 US States were used to evaluate lung cancer proportionate mortality over time by the usual occupation and industry reported on death certificates. Lung cancer proportionate mortality ratios were adjusted for smoking, using data from the National Health Interview Survey (NHIS) and the American Cancer Society's Cancer Prevention Study II. Analyses revealed that 194,382 white, 18,225 Black and 1,515 Hispanic women died 1984-1998 with lung cancer reported as the underlying cause of death. Following adjustment for smoking, significant excess proportionate lung cancer mortality was observed among US women working in the US manufacturing; transportation; retail trade; agriculture, forestry, and fishing; and nursing/personal care industries. Women employed in precision production, technical, managerial, professional specialty, and administrative occupations experienced some of the highest significantly excess proportionate lung cancer mortality during 1984-1998. The results of our study point to significantly elevated risks for lung cancer after adjustment for smoking among women in several occupations and industries. Because 6-17% of lung cancer in US males is attributable to known exposures to occupational carcinogens, and since synergistic interactions between cigarette smoke and other occupational lung carcinogens have been noted, it is important to continue research into the effects of occupational exposures on working men and women. Copyright © 2010 Wiley-Liss, Inc. JF - American journal of industrial medicine AU - Robinson, Cynthia F AU - Sullivan, Patricia A AU - Li, Jia AU - Walker, James T AD - The National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA. CFRobinson@cdc.gov Y1 - 2011/02// PY - 2011 DA - February 2011 SP - 102 EP - 117 VL - 54 IS - 2 KW - Index Medicus KW - Young Adult KW - Humans KW - Aged KW - Risk Assessment -- methods KW - Aged, 80 and over KW - Adult KW - Confidence Intervals KW - Incidence KW - Industry -- statistics & numerical data KW - Middle Aged KW - Adolescent KW - Environmental Exposure -- adverse effects KW - United States -- epidemiology KW - Female KW - Prevalence KW - Occupational Exposure -- statistics & numerical data KW - Lung Neoplasms -- etiology KW - Lung Neoplasms -- epidemiology KW - Occupational Diseases -- etiology KW - Occupational Exposure -- adverse effects KW - Occupational Diseases -- epidemiology KW - Lung Neoplasms -- mortality KW - Occupational Diseases -- mortality UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/847278896?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+journal+of+industrial+medicine&rft.atitle=Occupational+lung+cancer+in+US+women%2C+1984-1998.&rft.au=Robinson%2C+Cynthia+F%3BSullivan%2C+Patricia+A%3BLi%2C+Jia%3BWalker%2C+James+T&rft.aulast=Robinson&rft.aufirst=Cynthia&rft.date=2011-02-01&rft.volume=54&rft.issue=2&rft.spage=102&rft.isbn=&rft.btitle=&rft.title=American+journal+of+industrial+medicine&rft.issn=1097-0274&rft_id=info:doi/10.1002%2Fajim.20905 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-05-05 N1 - Date created - 2011-01-24 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1002/ajim.20905 ER - TY - JOUR T1 - Non-High-Density Lipoprotein Cholesterol Concentration is Associated with the Metabolic Syndrome among US Youth Aged 12-19 Years AN - 1038606448; 14253699 AB - Objective: To test the hypothesis that the concentration of non-high-density lipoprotein cholesterol (non-HDL-C) is associated with the metabolic syndrome (MetS) in youth. Study design: Data on children and adolescents aged 12-19 years (n = 2734) from the cross-sectional National Health and Nutrition Examination Survey 1999-2004 were analyzed. Results: Depending on the definition of MetS used, the mean non-HDL-C concentration among youth with MetS ranged from 144.2 to 155.8 mg/dL, compared with 108.8-109.1 mg/dL in those without MetS (all P =145 mg/dL - both significantly higher than the prevalence of 1.9%-3.4% in youth with a concentration =120 mg/dL or >=145 mg/dL were about 3 or 4 times more likely to have MetS compared with those with a non-HDL-C <120 mg/dL or <145 mg/dL (all P < .001). Conclusions: Fasting non-HDL-C concentration was strongly associated with MetS in US youth. Our results support the use of non-HDL-C thresholds of 120 mg/dL and 145 mg/dL to indicate borderline and high MetS risk, respectively. JF - Journal of Pediatrics AU - Li, Chaoyang AU - Ford, Earl S AU - McBride, Patrick E AU - Kwiterovich, Peter O AU - McCrindle, Brian W AU - Gidding, Samuel S AD - Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, cli@cdc.gov Y1 - 2011/02// PY - 2011 DA - Feb 2011 SP - 201 EP - 207 PB - Mosby, Inc. VL - 158 IS - 2 SN - 0022-3476, 0022-3476 KW - Toxicology Abstracts KW - Adolescence KW - Children KW - Cholesterol KW - Data processing KW - Fasting KW - Lipoproteins KW - Metabolic disorders KW - Nutrition KW - Risk factors KW - X 24490:Other UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1038606448?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Pediatrics&rft.atitle=Non-High-Density+Lipoprotein+Cholesterol+Concentration+is+Associated+with+the+Metabolic+Syndrome+among+US+Youth+Aged+12-19+Years&rft.au=Li%2C+Chaoyang%3BFord%2C+Earl+S%3BMcBride%2C+Patrick+E%3BKwiterovich%2C+Peter+O%3BMcCrindle%2C+Brian+W%3BGidding%2C+Samuel+S&rft.aulast=Li&rft.aufirst=Chaoyang&rft.date=2011-02-01&rft.volume=158&rft.issue=2&rft.spage=201&rft.isbn=&rft.btitle=&rft.title=Journal+of+Pediatrics&rft.issn=00223476&rft_id=info:doi/10.1016%2Fj.jpeds.2010.07.050 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-09-01 N1 - Last updated - 2012-09-10 N1 - SubjectsTermNotLitGenreText - Data processing; Risk factors; Adolescence; Metabolic disorders; Lipoproteins; Fasting; Cholesterol; Children; Nutrition DO - http://dx.doi.org/10.1016/j.jpeds.2010.07.050 ER - TY - JOUR T1 - Awareness and Utilization of BRCA1/2 Testing Among U.S. Primary Care Physicians AN - 954614329; 14256023 AB - Testing for mutations in the breast and ovarian cancer susceptibility genes BRCA1 and BRCA2 (BRCA) has been commercially available since 1996 This study sought to determine, among U.S. primary care physicians, the level of awareness and utilization of BRCA testing and the 2005 U.S. Preventive Services Task Force (USPSTF) recommendations. Methods: In 2009, data were analyzed on 1500 physician respondents to the 2007 DocStyles national survey (515 family practitioners, 485 internists, 250 pediatricians, and 250 obstetricians/gynecologists). Results: Overall, 87% of physicians were aware of BRCA testing, and 25% reported having ordered testing for at least one patient in the past year. Ordering tests was most prevalent among obstetricians/gynecologists in practice for more than 10 years, with more affluent patients. Physicians were asked to select indications for BRCA testing from seven different clinical scenarios representing increased (4) or low-risk (3) situations consistent with the USPSTF guidelines. Among ordering physicians (pediatricians excluded), 45% chose at least one low-risk scenario as an indication for BRCA testing. Only 19% correctly selected all of the increased-risk and none of the low-risk scenarios. Conclusions: A substantial majority of primary care physicians are aware of BRCA testing and many report having ordered at least one test within the past year. A minority, however, appear to consistently recognize the family history patterns identified by the USPSTF as appropriate indications for BRCA evaluation. These results suggest the need to improve providers' knowledge about existing recommendations - particularly in this era of increased BRCA direct-to-consumer marketing. JF - American Journal of Preventive Medicine AU - Bellcross, Cecelia A AU - Kolor, Katherine AU - Goddard, Katrina AB AU - Coates, Ralph J AU - Reyes, Michele AU - Khoury, Muin J AD - Office of Public Health Genomics, CDC, Atlanta, Georgia, cbellcross@cdc.gov Y1 - 2011/01// PY - 2011 DA - Jan 2011 SP - 61 EP - 66 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 40 IS - 1 SN - 0749-3797, 0749-3797 KW - Risk Abstracts KW - Genetics KW - USA KW - marketing KW - guidelines KW - ovarian carcinoma KW - Mutation KW - affluence KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/954614329?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Awareness+and+Utilization+of+BRCA1%2F2+Testing+Among+U.S.+Primary+Care+Physicians&rft.au=Bellcross%2C+Cecelia+A%3BKolor%2C+Katherine%3BGoddard%2C+Katrina+AB%3BCoates%2C+Ralph+J%3BReyes%2C+Michele%3BKhoury%2C+Muin+J&rft.aulast=Bellcross&rft.aufirst=Cecelia&rft.date=2011-01-01&rft.volume=40&rft.issue=1&rft.spage=61&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2010.09.027 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - Genetics; guidelines; marketing; ovarian carcinoma; Mutation; affluence; USA DO - http://dx.doi.org/10.1016/j.amepre.2010.09.027 ER - TY - JOUR T1 - Characteristics of Elderly and Other Vulnerable Adult Victims of Homicide by a Caregiver: National Violent Death Reporting System--17 U.S. States, 2003-2007 AN - 954612523; 14162278 AB - Homicides of dependent elderly and nonelderly adults by their caregivers violate trust and have long-term consequences for families. A better understanding of the characteristics of homicide by caregivers may provide insights that can inform prevention efforts. Data collected in the National Violent Death Reporting System (NVDRS) between 2003 and 2007 are used to characterize victims, perpetrators, and caregiver roles, and circumstances that precipitated homicides by a caregiver. A total 68 incidents are categorized into either homicide by neglect ( n = 17), intentional injury of the victim only (n = 21), or homicide followed by suicide of the perpetrator (n = 30). Demographics, mechanism of injury, location of injury, and victim--suspect relationship variables are supplemented by narrative accounts of incidents. In general, findings show that adult homicide victims of a caregiver were widowed (42.6%), non-Hispanic (97.1%), White (88.2%), women (63.2%) killed in their homes (92.6%) with a firearm (35.3%) or by intentional neglect (25.0%) by a husband (30.9%) or a son (22.1%). Nearly half were aged 80 years and older (48.5%), 42.6% were aged 50 to 79 years, and 0.9% were aged 20 to 49 years. Many homicide by caregiver incidents are precipitated by physical illness of the victim or caregiver, opportunity for perpetrator financial gain, mental illness of the caregiver, substance use by the caregiver, or an impending crisis in the life of the caregiver not related to illness. Understanding the vulnerabilities of victims, the characteristics of suspects, and the multiple types of motivations is key to developing effective prevention efforts. JF - Journal of Interpersonal Violence AU - Karch, Debra AU - Nunn, Kelly Cole AD - Centers for Disease Control and Prevention, DKarch@cdc.gov Y1 - 2011/01// PY - 2011 DA - Jan 2011 SP - 137 EP - 157 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU UK VL - 26 IS - 1 SN - 0886-2605, 0886-2605 KW - Risk Abstracts KW - demography KW - Mortality KW - USA KW - homicide KW - Injuries KW - firearms KW - prevention KW - vulnerability KW - elderly KW - suicide KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/954612523?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Interpersonal+Violence&rft.atitle=Characteristics+of+Elderly+and+Other+Vulnerable+Adult+Victims+of+Homicide+by+a+Caregiver%3A+National+Violent+Death+Reporting+System--17+U.S.+States%2C+2003-2007&rft.au=Karch%2C+Debra%3BNunn%2C+Kelly+Cole&rft.aulast=Karch&rft.aufirst=Debra&rft.date=2011-01-01&rft.volume=26&rft.issue=1&rft.spage=137&rft.isbn=&rft.btitle=&rft.title=Journal+of+Interpersonal+Violence&rft.issn=08862605&rft_id=info:doi/10.1177%2F0886260510362890 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Number of references - 32 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - demography; Mortality; homicide; Injuries; firearms; prevention; vulnerability; elderly; suicide; USA DO - http://dx.doi.org/10.1177/0886260510362890 ER - TY - JOUR T1 - Antimicrobial Resistance among Invasive Nontyphoidal Salmonella enterica Isolates in the United States: National Antimicrobial Resistance Monitoring System, 1996 to 2007 AN - 907156639; 14403418 AB - Nontyphoidal salmonellae (NTS) are important causes of community-acquired bloodstream infection. We describe patterns of antimicrobial resistance among invasive NTS in the United States. We compared bloodstream NTS isolates with those from stool submitted to the National Antimicrobial Resistance Monitoring System (NARMS) from 1996 to 2007. We describe antimicrobial resistance among invasive strains by serogroup and serotype. Of the 19,302 NTS isolates, 17,804 (92.2%) were from stool or blood. Of these, 1,050 (5.9%) were bloodstream isolates. The median ages (ranges) of patients with and without bacteremia were 36 (<1 to 97) years and 20 (<1 to 105) years, respectively (P < 0.001). Males (odds ratio [OR], 1.21; 95% confidence interval [CI], 1.06 to 1.38) and those greater than or equal to 65 years of age were at greater risk for invasive disease. Salmonella enterica serotypes Enteritidis, Typhimurium, and Heidelberg were the most common serotypes isolated from blood; S. enterica serotypes Dublin, Sandiego, and Schwarzengrund were associated with the greatest risk for bloodstream isolation. Of invasive isolates, 208 (19.8%) were resistant to ampicillin, 117 (11.1%) to chloramphenicol, and 26 (2.5%) to trimethoprim-sulfamethoxazole; 28 (2.7%) isolates were resistant to nalidixic acid and 26 (2.5%) to ceftriaxone. Antimicrobial resistance to traditional agents is common. However, the occurrence of nalidixic acid and ceftriaxone resistance among invasive NTS is cause for clinical and public health vigilance. JF - Antimicrobial Agents & Chemotherapy AU - Crump, John A AU - Medalla, Felicita M AU - Joyce, Kevin W AU - Krueger, Amy L AU - Hoekstra, RMichael AU - Whichard, Jean M AU - Barzilay, Ezra J AD - Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30329 Y1 - 2011 PY - 2011 DA - 2011 SP - 1148 EP - 1154 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 55 IS - 3 SN - 0066-4804, 0066-4804 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Chloramphenicol KW - Age KW - Serotypes KW - Drug resistance KW - Bacteremia KW - Ampicillin KW - trimethoprim-sulfamethoxazole KW - Ceftriaxone KW - Infection KW - Public health KW - Blood KW - Salmonella enterica KW - Nalidixic acid KW - Vigilance KW - Feces KW - Solitary tract nucleus KW - A 01340:Antibiotics & Antimicrobials KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/907156639?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Antimicrobial+Resistance+among+Invasive+Nontyphoidal+Salmonella+enterica+Isolates+in+the+United+States%3A+National+Antimicrobial+Resistance+Monitoring+System%2C+1996+to+2007&rft.au=Crump%2C+John+A%3BMedalla%2C+Felicita+M%3BJoyce%2C+Kevin+W%3BKrueger%2C+Amy+L%3BHoekstra%2C+RMichael%3BWhichard%2C+Jean+M%3BBarzilay%2C+Ezra+J&rft.aulast=Crump&rft.aufirst=John&rft.date=2011-01-01&rft.volume=55&rft.issue=3&rft.spage=1148&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Age; Chloramphenicol; Serotypes; Drug resistance; Ampicillin; Bacteremia; trimethoprim-sulfamethoxazole; Ceftriaxone; Infection; Public health; Blood; Nalidixic acid; Vigilance; Solitary tract nucleus; Feces; Salmonella enterica ER - TY - JOUR T1 - Prevention of intellectual disability through screening for congenital hypothyroidism: how much and at what level? AN - 904472606; 14515846 AB - OBJECTIVE: Congenital hypothyroidism (CHT) is a common cause of preventable mental retardation, and the quantification of intellectual disability due to CHT is needed to assess the public health benefit of newborn screening. DESIGN: Review of published studies conducted among children born prior to the introduction of newborn screening for CHT and reporting cognitive test scores. SETTING: Population-based studies. PATIENTS: Children with clinically diagnosed CHT. INTERVENTIONS: Thyroid hormone substitution. MAIN OUTCOME MEASURES: Intelligence quotient (IQ) (mean and distribution). RESULTS: The prevalence of recognised CHT rose from one in 6500 prior to screening to approximately one in 3000 with screening. In four population-based studies in high-income countries, among children with clinically diagnosed CHT 8-28% were classified as having intellectual disability (defined as an IQ <70) and the mean IQ was 85 (a leftward shift of 1 SD). Among children with subclinical CHT, the risk of overt intellectual disability was lower (zero in one study), but decreased intellectual potential and increased behavioural abnormalities were documented. CONCLUSIONS: Although the prevalence of overt disability among children with CHT in the absence of screening may be less than previously estimated, the preventable burden of intellectual disability due to CHT is substantial and justifies newborn screening. However, changes in existing newborn screening protocols to capture more cases are unlikely to prevent overt cases of disability and should therefore be justified instead by the documentation of other benefits of early detection. JF - Archives of Disease in Childhood AU - Grosse, Scott D AU - Van Vliet, Guy AD - Division of Blood Disorders, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA Y1 - 2011 PY - 2011 DA - 2011 SP - 374 EP - 379 PB - British Medical Association, BMA House Square London WC1H 9JP UK VL - 96 IS - 4 SN - 0003-9888, 0003-9888 KW - Risk Abstracts KW - disabilities KW - Thyroid KW - Children KW - Hormones KW - Public health KW - Reviews KW - intervention KW - prevention KW - intelligence KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/904472606?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Archives+of+Disease+in+Childhood&rft.atitle=Prevention+of+intellectual+disability+through+screening+for+congenital+hypothyroidism%3A+how+much+and+at+what+level%3F&rft.au=Grosse%2C+Scott+D%3BVan+Vliet%2C+Guy&rft.aulast=Grosse&rft.aufirst=Scott&rft.date=2011-01-01&rft.volume=96&rft.issue=4&rft.spage=374&rft.isbn=&rft.btitle=&rft.title=Archives+of+Disease+in+Childhood&rft.issn=00039888&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - disabilities; intervention; Reviews; prevention; Thyroid; Children; Hormones; intelligence; Public health ER - TY - JOUR T1 - Non-fatal conductive energy device-related injuries treated in US emergency departments, 2005-2008 AN - 904469594; 14592601 AB - This paper provides the first US estimates and rates of non-fatal conductive energy device (CED)-related (eg, Taser) injuries relative to other types of legal intervention injuries treated in hospital emergency departments (EDs). The data used for this study were from the National Electronic Injury Surveillance System (NEISS), including the Firearm Injury Surveillance Study (NEISS-FISS) and the All Injury Program (NEISS-AIP). Of an average annual 75 000 suspects treated for non-fatal legal intervention injuries, 11% had injuries that were associated with the use of a CED or Taser. Of the suspects with non-fatal CED-related injuries, 90.1% were males, 72.6% were 20-44 years of age, and 55.2% were injured to the trunk. Most suspects with CED-related injuries (93.6%) were treated and released from the hospital ED. The authors conclude that NEISS is a useful data source for CED-related injuries in the US; estimates from NEISS emphasise the importance of implementing CED safety guidelines by law enforcement officers and training of medical personnel to help reduce the risk of severe injury and potential adverse health consequences. JF - Injury Prevention AU - Haileyesus, Tadesse AU - Annest, Joseph L AU - Mercy, James A AD - Office of Statistics and Programming, National Center for Injury Prevention and Control, National Centers for Disease Control and Prevention, Atlanta, Georgia, USA Y1 - 2011 PY - 2011 DA - 2011 SP - 127 EP - 130 PB - B M J Publishing Group, B.M.A. House London WC1H 9JR UK VL - 17 IS - 2 SN - 1353-8047, 1353-8047 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Injuries KW - firearms KW - Medical personnel KW - risk reduction KW - USA KW - guidelines KW - intervention KW - law enforcement KW - emergency medical services KW - Hospitals KW - H 10000:Ergonomics/Human Factors KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/904469594?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Injury+Prevention&rft.atitle=Non-fatal+conductive+energy+device-related+injuries+treated+in+US+emergency+departments%2C+2005-2008&rft.au=Haileyesus%2C+Tadesse%3BAnnest%2C+Joseph+L%3BMercy%2C+James+A&rft.aulast=Haileyesus&rft.aufirst=Tadesse&rft.date=2011-01-01&rft.volume=17&rft.issue=2&rft.spage=127&rft.isbn=&rft.btitle=&rft.title=Injury+Prevention&rft.issn=13538047&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - risk reduction; Injuries; guidelines; firearms; intervention; law enforcement; Medical personnel; emergency medical services; Hospitals; USA ER - TY - JOUR T1 - The burden of childhood injuries and evidence based strategies developed using the injury surveillance system in Pasto, Colombia AN - 904469306; 14300080 AB - OBJECTIVE: This article characterises the burden of childhood injuries and provides examples of evidence-based injury prevention strategies developed using a citywide injury surveillance system in Pasto, Colombia. METHODS: Fatal (2003-2007) and non-fatal (2006-2007) childhood injury data were analysed by age, sex, cause, intent, place of occurrence, and disposition. RESULTS: Boys accounted for 71.5% of fatal and 64.9% of non-fatal injuries. The overall fatality rate for all injuries was 170.8 per 100,000 and the non-fatal injury rate was 4,053 per 100,000. Unintentional injuries were the leading causes of fatal injuries for all age groups, except for those 15-19 years whose top four leading causes were violence-related. Among non-fatal injuries, falls was the leading mechanism in the group 0-14 years. Interpersonal violence with a sharp object was the most important cause for boys aged 15-19 years. Home was the most frequent place of occurrence for both fatal and non-fatal injuries for young children 0-4 years old. Home, school and public places became an important place for injuries for boys in the age group 5-15 years. The highest case-fatality rate was for self-inflicted injuries (8.9%). CONCLUSIONS: Although some interventions have been implemented in Pasto to reduce injuries, it is necessary to further explore risk factors to better focus prevention strategies and their evaluation. We discuss three evidence-based strategies developed to prevent firework-related injuries during festival, self-inflicted injuries, and road traffic-related injuries, designed and implemented based on the injury surveillance data. JF - Injury Prevention AU - Espitia-Hardeman, Victoria AU - Borse, Nagesh N AU - Dellinger, Ann M AU - Betancourt, Carmen Elena AU - Villareal, Alba Nelly AU - Caicedo, Luz Diana AU - Portillo, Carlos AD - The Division of Violence Prevention, National Center for Injury Prevention and Control, at the Centers for Disease Control and Prevention, Atlanta, Georgia, USA Y1 - 2011 PY - 2011 DA - 2011 SP - i38 EP - i44 PB - B M J Publishing Group, B.M.A. House London WC1H 9JR UK VL - 17 SN - 1353-8047, 1353-8047 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Mortality KW - Age KW - Injuries KW - Colombia KW - Children KW - Violence KW - schools KW - Risk factors KW - intervention KW - prevention KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/904469306?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Injury+Prevention&rft.atitle=The+burden+of+childhood+injuries+and+evidence+based+strategies+developed+using+the+injury+surveillance+system+in+Pasto%2C+Colombia&rft.au=Espitia-Hardeman%2C+Victoria%3BBorse%2C+Nagesh+N%3BDellinger%2C+Ann+M%3BBetancourt%2C+Carmen+Elena%3BVillareal%2C+Alba+Nelly%3BCaicedo%2C+Luz+Diana%3BPortillo%2C+Carlos&rft.aulast=Espitia-Hardeman&rft.aufirst=Victoria&rft.date=2011-01-01&rft.volume=17&rft.issue=&rft.spage=i38&rft.isbn=&rft.btitle=&rft.title=Injury+Prevention&rft.issn=13538047&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2012-04-06 N1 - SubjectsTermNotLitGenreText - Mortality; Age; schools; Injuries; intervention; Risk factors; prevention; Children; Violence; Colombia ER - TY - JOUR T1 - Maternal Smoking and Congenital Heart Defects in the Baltimore-Washington Infant Study AN - 904466268; 14453326 AB - OBJECTIVE: We investigated associations between maternal cigarette smoking during the first trimester and the risk of congenital heart defects (CHDs) among the infants. METHODS: The Baltimore-Washington Infant Study was the first population-based case-control study of CHDs conducted in the United States. Case and control infants were enrolled during the period 1981-1989. We excluded mothers with overt pregestational diabetes and case mothers whose infants had noncardiac anomalies (with the exception of atrioventricular septal defects with Down syndrome) from the analysis, which resulted in 2525 case and 3435 control infants. Self-reported first-trimester maternal cigarette consumption was ascertained via an in-person interview after delivery. Associations for 26 different groups of CHDs with maternal cigarette consumption were estimated by using logistic regression models. Odds ratios (ORs) corresponded to a 20-cigarette-per-day increase in consumption. RESULTS: We observed statistically significant positive associations between self-reported first-trimester maternal cigarette consumption and the risk of secundum-type atrial septal defects (OR: 1.36 [95% confidence interval (CI): 1.04-1.78]), right ventricular outflow tract defects (OR: 1.32 [95% CI: 1.06-1.65]), pulmonary valve stenosis (OR: 1.35 [95% CI: 1.05-1.74]), truncus arteriosus (OR: 1.90 [95% CI: 1.04-3.45]), and levo-transposition of the great arteries (OR: 1.79 [95% CI: 1.04-3.10]). A suggestive association was observed for atrioventricular septal defects among infants without Down syndrome (OR: 1.50 [95% CI: 0.99-2.29]). CONCLUSIONS: These findings add to the existing body of evidence that implicates first-trimester maternal cigarette smoking as a modest risk factor for select CHD phenotypes. JF - Pediatrics AU - Alverson, Clinton J AU - Strickland, Matthew J AU - Gilboa, Suzanne M AU - Correa, Adolfo AD - Division of Birth Defects and Developmental Disabilities, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia Y1 - 2011 PY - 2011 DA - 2011 SP - e647 EP - e653 PB - American Academy of Pediatrics, 141 Northwest Point Blvd. Elk Grove Village IL 60007-1098 USA VL - 127 IS - 3 SN - 1098-4275, 1098-4275 KW - Risk Abstracts KW - USA KW - diabetes mellitus KW - Cigarettes KW - Risk factors KW - outflow KW - Infants KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/904466268?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Pediatrics&rft.atitle=Maternal+Smoking+and+Congenital+Heart+Defects+in+the+Baltimore-Washington+Infant+Study&rft.au=Alverson%2C+Clinton+J%3BStrickland%2C+Matthew+J%3BGilboa%2C+Suzanne+M%3BCorrea%2C+Adolfo&rft.aulast=Alverson&rft.aufirst=Clinton&rft.date=2011-01-01&rft.volume=127&rft.issue=3&rft.spage=e647&rft.isbn=&rft.btitle=&rft.title=Pediatrics&rft.issn=10984275&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - diabetes mellitus; Cigarettes; Risk factors; outflow; Infants; USA ER - TY - JOUR T1 - History of maltreatment among unintentional injury deaths: analyses of Texas child fatality review data, 2005-2007 AN - 904465224; 14300085 AB - OBJECTIVE: This report examines unintentional injury deaths among children with and without a history of child maltreatment. METHODS: Data are from reviews of 1192 unintentional injury deaths occurring among children in Texas during 2005-2007. The study examined differences in child demographic characteristics, injury mechanism, and supervisor status at time of death between children with and without maltreatment history by using descriptive statistics and chi 2 tests. Separate analyses compared characteristics of asphyxia, drowning, and poisoning deaths. RESULTS: In 10% of the unintentional injury deaths that were reviewed, the child had a history of maltreatment. The prevalence of a history of maltreatment was highest among black decedents and lowest among white decedents. Prevalence of a history of maltreatment was highest among infant decedents and lowest among youth decedents, ages 10-14 years. Among deaths where there was no maltreatment history, 54% were due to motor vehicle related incidents, whereas 51% of deaths among children with maltreatment history were caused by drowning, asphyxia, and poisoning. Supervisors of child decedents with a history of maltreatment were significantly more likely to have been alcohol impaired (6.9% vs 1.6%; p<0.0005), or asleep (12.1% vs 6.6%; p=0.03) at the time of death. Differences between child decedents with and without maltreatment history were observed in infant sleep surface in suffocation deaths, location and barrier type in drowning deaths, and substance type in poisoning deaths. CONCLUSIONS: These data show that the mechanisms and circumstances surrounding unintentional injury deaths among children with a history of maltreatment differ from those without a history of maltreatment. This underscores the need for appropriate interventions to prevent unintentional and intentional injuries in families with a history of maltreatment. JF - Injury Prevention AU - Parks, Sharyn E AU - Mirchandani, Gita AU - Rodriguez, Susan AU - Hellsten, John AD - Centers for Disease Control and Prevention, National Center for Injury Prevention and Control, Atlanta, GA, USA Y1 - 2011 PY - 2011 DA - 2011 SP - i14 EP - i18 PB - B M J Publishing Group, B.M.A. House London WC1H 9JR UK VL - 17 SN - 1353-8047, 1353-8047 KW - Health & Safety Science Abstracts KW - Mortality KW - Historical account KW - Alcohol KW - Injuries KW - Poisoning KW - Children KW - Reviews KW - USA, Texas KW - drowning KW - Infants KW - H 2000:Transportation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/904465224?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Injury+Prevention&rft.atitle=History+of+maltreatment+among+unintentional+injury+deaths%3A+analyses+of+Texas+child+fatality+review+data%2C+2005-2007&rft.au=Parks%2C+Sharyn+E%3BMirchandani%2C+Gita%3BRodriguez%2C+Susan%3BHellsten%2C+John&rft.aulast=Parks&rft.aufirst=Sharyn&rft.date=2011-01-01&rft.volume=17&rft.issue=&rft.spage=i14&rft.isbn=&rft.btitle=&rft.title=Injury+Prevention&rft.issn=13538047&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Alcohol; Historical account; Mortality; Injuries; Reviews; Poisoning; Children; drowning; Infants; USA, Texas ER - TY - JOUR T1 - Exposure science for viral diseases: 2009 H1N1 pandemic influenza virus AN - 904465145; 14164392 JF - Journal of Exposure Science and Environmental Epidemiology AU - Cox, Nancy AU - Donis, Ruben AU - Barr, John R AD - Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA Y1 - 2011/01// PY - 2011 DA - Jan 2011 SP - 1 EP - 2 PB - Nature Publishing Group, The Macmillan Building London N1 9XW UK VL - 21 IS - 1 SN - 1559-0631, 1559-0631 KW - Toxicology Abstracts KW - Influenza virus KW - viral diseases KW - influenza UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/904465145?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Exposure+Science+and+Environmental+Epidemiology&rft.atitle=Exposure+science+for+viral+diseases%3A+2009+H1N1+pandemic+influenza+virus&rft.au=Cox%2C+Nancy%3BDonis%2C+Ruben%3BBarr%2C+John+R&rft.aulast=Cox&rft.aufirst=Nancy&rft.date=2011-01-01&rft.volume=21&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Journal+of+Exposure+Science+and+Environmental+Epidemiology&rft.issn=15590631&rft_id=info:doi/10.1038%2Fjes.2010.52 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - viral diseases; influenza; Influenza virus DO - http://dx.doi.org/10.1038/jes.2010.52 ER - TY - JOUR T1 - State Legislative Efforts to Support Fruit and Vegetable Access, Affordability, and Availability, 2001 to 2009: A Systematic Examination of Policies AN - 896187615; 2011-123860 AB - Individual interventions to increase fruit and vegetable (F&V) consumption are being augmented with environmental and policy approaches. This study examined 2001 to 2009 state legislation supportive of F&V. Using two databases, 478 unique bills were identified, 31% of which were enacted. Bills related to local procurement/direct marketing and healthier food retail were most common: 186 introduced, 58 enacted; 159 introduced (65 enacted in the healthier food retail topic area), respectively. Other topics included general access and affordability, food system support, and food policy councils. Legislation increased over time; 6 bills were introduced in 2001 (3 enacted), and 138 were introduced in 2009 (31 enacted). Policy surveillance of a food system app roach to supporting F&V allows stakeholders from many fields to understand policy approaches to improving health and potential cobenefits of these policies. Adapted from the source document. JF - Journal of Hunger & Environmental Nutrition AU - Ann Kim, Sonia AU - Michels Blanck, Heidi AD - Division of Nutrition, Physical Activity, and Obesity, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Hwy, MS K-25; Atlanta, GA 30341 Y1 - 2011/01// PY - 2011 DA - January 2011 SP - 99 EP - 113 PB - Taylor & Francis Group, Philadephia, PA VL - 6 IS - 1 SN - 1932-0248, 1932-0248 KW - Health conditions and policy - Food and nutrition KW - Law and ethics - Law and jurisprudence KW - Business and service sector - Markets, marketing, and merchandising KW - Economic conditions and policy - Consumers and consumption KW - Law and ethics - Criminal law KW - Government - Internal security KW - legislation, public policy, health promotion, fruit, vegetable, food access KW - Food supply KW - Purchasing KW - Food KW - Consumption KW - Marketing KW - Surveillance KW - Legislation KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/896187615?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Hunger+%26+Environmental+Nutrition&rft.atitle=State+Legislative+Efforts+to+Support+Fruit+and+Vegetable+Access%2C+Affordability%2C+and+Availability%2C+2001+to+2009%3A+A+Systematic+Examination+of+Policies&rft.au=Ann+Kim%2C+Sonia%3BMichels+Blanck%2C+Heidi&rft.aulast=Ann+Kim&rft.aufirst=Sonia&rft.date=2011-01-01&rft.volume=6&rft.issue=1&rft.spage=99&rft.isbn=&rft.btitle=&rft.title=Journal+of+Hunger+%26+Environmental+Nutrition&rft.issn=19320248&rft_id=info:doi/10.1080%2F19320248.2011.554262 LA - English DB - PAIS Index N1 - Date revised - 2011-10-03 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Food; Food supply; Legislation; Marketing; Consumption; Surveillance; Purchasing DO - http://dx.doi.org/10.1080/19320248.2011.554262 ER - TY - JOUR T1 - Physical Activity in U.S. Older Adults with Diabetes Mellitus: Prevalence and Correlates of Meeting Physical Activity Recommendations AN - 879471041; 14224780 AB - OBJECTIVES: To compare the prevalence and correlates of meeting current recommendations for physical activity in older adults with and without diabetes mellitus (DM) in the United States. DESIGN: A cross-sectional, population-based sample. SETTING: The 2007 Behavioral Risk Factor Surveillance Survey, which employs random-digit dialing to interview noninstitutionalized U.S. adults. PARTICIPANTS: Ninety-nine thousand one hundred seventy-two adults (18,370 with DM) aged 65 and older. MEASUREMENTS: The age-adjusted prevalence and the odds ratios for physical activity patterns (defined on the basis of the physical activity guidelines from the American Diabetes Association (ADA 2007) and the Department of Health and Human Services (DHHS 2008)) were obtained using multiple logistic regression analyses. The correlates of meeting physical activity recommendations were assessed using log-binomial regression analyses. RESULTS: Overall, 25% and 42% of older adults with diabetes mellitus met recommendations for total physical activity based on the ADA 2007 and the DHHS 2008 guidelines, respectively. Adults with DM were 31% to 34% (P<.001) less likely to engage in physical activity at recommended levels and 13% to 19% (P<.001) less likely to be physically active at insufficient levels than those without DM. Analyses limited to participants who reported no disability yielded similar results. In adults with DM, older age ( greater than or equal to 75); being female; being non-Hispanic black; and having obesity, coronary heart disease, and disability were associated with less likelihood, whereas advanced educational status was associated with greater likelihood of meeting physical activity recommendations. CONCLUSION: In the United States, efforts to boost physical activity participation in older adults with DM are needed. JF - Journal of the American Geriatrics Society AU - Zhao, Guixiang AU - Ford, Earl S AU - Li, Chaoyang AU - Balluz, Lina S AD - From the Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia. Y1 - 2011/01// PY - 2011 DA - Jan 2011 SP - 132 EP - 137 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 USA VL - 59 IS - 1 SN - 0002-8614, 0002-8614 KW - Physical Education Index; Health & Safety Science Abstracts; Risk Abstracts KW - Handicapped KW - Measurement KW - Age KW - disabilities KW - obesity KW - Gerontology KW - Exercise KW - Adults KW - Diabetes KW - USA KW - diabetes mellitus KW - guidelines KW - Health (services) KW - Risk factors KW - Analysis KW - Cardiovascular diseases KW - physical activity KW - Heart diseases KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - R2 23060:Medical and environmental health KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/879471041?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+American+Geriatrics+Society&rft.atitle=Physical+Activity+in+U.S.+Older+Adults+with+Diabetes+Mellitus%3A+Prevalence+and+Correlates+of+Meeting+Physical+Activity+Recommendations&rft.au=Zhao%2C+Guixiang%3BFord%2C+Earl+S%3BLi%2C+Chaoyang%3BBalluz%2C+Lina+S&rft.aulast=Zhao&rft.aufirst=Guixiang&rft.date=2011-01-01&rft.volume=59&rft.issue=1&rft.spage=132&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+American+Geriatrics+Society&rft.issn=00028614&rft_id=info:doi/10.1111%2Fj.1532-5415.2010.03236.x LA - English DB - Physical Education Index; ProQuest Environmental Science Collection N1 - Date revised - 2011-07-01 N1 - Document feature - figure 1 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - Measurement; Handicapped; Health (services); Analysis; Gerontology; Adults; Exercise; Heart diseases; Diabetes; Age; diabetes mellitus; disabilities; guidelines; Risk factors; obesity; Cardiovascular diseases; physical activity; USA DO - http://dx.doi.org/10.1111/j.1532-5415.2010.03236.x ER - TY - JOUR T1 - Tuberculosis Among Persons Born in the Philippines and Living in the United States, 2000-2007 AN - 872124567; 14047302 AB - OBJECTIVES: We examined demographic, clinical, and treatment outcome characteristics of Filipinos with tuberculosis (TB) in the United States. METHODS: We calculated TB case rates from US Census Bureau population estimates and National Tuberculosis Surveillance System data for US-born non-Hispanic Whites and for US residents born in the Philippines, India, China, Cambodia, Vietnam, Pakistan, and Korea--countries that are major contributors to the TB burden in the United States. We compared Filipinos with the other groups through univariate and multivariate analyses. RESULTS: Of 45 504 TB patients, 15.5% were Filipinos; 43.0% were other Asian/Pacific Islander groups; and 41.6% were Whites. Per 100 000 persons in 2007, the TB rate was 73.5 among Cambodians, 54.0 among Vietnamese, 52.1 among Filipinos, and 0.9 among Whites. Filipinos were more likely than other groups to be employed as health care workers and to have used private health care providers but less likely to be HIV positive and to be offered HIV testing. CONCLUSIONS: The relatively high TB rate among Filipinos indicates that TB control strategies should target this population. Providers should be encouraged to offer HIV testing to all TB patients. JF - American Journal of Public Health AU - Manangan, Lilia Ponce AU - Salibay, Catheryn Jumao-as AU - MacLaren Wallace, Ryan AU - Kammerer, Steve AU - Pratt, Robert AU - McAllister, Laura AU - Robison, Valerie AD - At the time of the study, Lilia Ponce Manangan, Ryan MacLaren Wallace, and Valerie Robison were with the Division of Tuberculosis Elimination, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention (CDC), Atlanta, GA Y1 - 2011 PY - 2011 DA - 2011 SP - 101 EP - 111 PB - American Public Health Association, 1015 15th St., N.W. Washington DC 20005 USA VL - 101 IS - 1 SN - 0090-0036, 0090-0036 KW - Microbiology Abstracts B: Bacteriology KW - Demography KW - Data processing KW - Human immunodeficiency virus KW - Mycobacterium KW - Multivariate analysis KW - Tuberculosis KW - Census KW - Medical personnel KW - Public health KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/872124567?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Public+Health&rft.atitle=Tuberculosis+Among+Persons+Born+in+the+Philippines+and+Living+in+the+United+States%2C+2000-2007&rft.au=Manangan%2C+Lilia+Ponce%3BSalibay%2C+Catheryn+Jumao-as%3BMacLaren+Wallace%2C+Ryan%3BKammerer%2C+Steve%3BPratt%2C+Robert%3BMcAllister%2C+Laura%3BRobison%2C+Valerie&rft.aulast=Manangan&rft.aufirst=Lilia&rft.date=2011-01-01&rft.volume=101&rft.issue=1&rft.spage=101&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Public+Health&rft.issn=00900036&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-06-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Demography; Data processing; Multivariate analysis; Census; Tuberculosis; Medical personnel; Public health; Mycobacterium; Human immunodeficiency virus ER - TY - JOUR T1 - Driving self-restriction in high-risk conditions: How do older drivers compare to others? AN - 867739857; 14602333 AB - Many older drivers self-restrict or avoid driving under high-risk conditions. Little is known about the onset of driving self-restrictions or how widespread self-restrictions are among drivers of all ages. Methods: The Second Injury Control and Risk Survey (ICARIS-2) was a nationwide cross-sectional, list-assisted random-digit-dial telephone survey from 2001 to 2003. National prevalence estimates and weighted percentages of those reporting driving self-restrictions were calculated. Multivariable logistic regression was used to explore associations between specific self-restrictions and age group, adjusting for other personal characteristics. Results: More than half of all drivers reported at least one driving self-restriction. The most commonly reported restriction was avoidance of driving in bad weather (47.5%), followed by at night (27.9%) and on highways or high-speed roads (19%). A greater percentage of young adult women (18-24 years) reported self-restricting in bad weather compared to women in other age groups, and the percentage of drivers self-restricting at night, in bad weather, and on highways or high-speed roads increased steeply after age 64. We found that women, those in low income groups, and those who had driven low annual mileage were more likely to self-restrict. Conclusions: In addition to assessing self-restrictions among older drivers, a new finding from our study is that self-restrictions are also quite prevalent among younger age groups. Driving self-restrictions may be better understood as a spectrum across ages in which drivers' reasons for restriction change. Impact on industry: Future research on the ability of driving self-restrictions to reduce actual crash risk and prevent injuries is needed. Research Highlights: About half of all drivers, an estimated 87 million persons, self-restricted their driving. The most commonly reported restriction was avoidance of driving in bad weather (47.5%). Driving self-restrictions were prevalent at not only older ages but also younger ages. Women, those in low income groups, and those who had driven low annual mileage were more likely to self-restrict. Driving self-restrictions may be better understood as a spectrum across ages in which drivers' reasons for restriction change. JF - Journal of Safety Research AU - Naumann, Rebecca B AU - Dellinger, Ann M AU - Kresnow, Marcie-Jo AD - Division of Unintentional Injury Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA, USA, RNaumann@cdc.gov Y1 - 2011 PY - 2011 DA - 2011 SP - 67 EP - 71 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK VL - 42 IS - 1 SN - 0022-4375, 0022-4375 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Weather KW - age groups KW - Age KW - Injuries KW - young adults KW - low income groups KW - Highways KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/867739857?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Safety+Research&rft.atitle=Driving+self-restriction+in+high-risk+conditions%3A+How+do+older+drivers+compare+to+others%3F&rft.au=Naumann%2C+Rebecca+B%3BDellinger%2C+Ann+M%3BKresnow%2C+Marcie-Jo&rft.aulast=Naumann&rft.aufirst=Rebecca&rft.date=2011-01-01&rft.volume=42&rft.issue=1&rft.spage=67&rft.isbn=&rft.btitle=&rft.title=Journal+of+Safety+Research&rft.issn=00224375&rft_id=info:doi/10.1016%2Fj.jsr.2010.12.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-05-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - age groups; Weather; Age; Injuries; low income groups; young adults; Highways DO - http://dx.doi.org/10.1016/j.jsr.2010.12.001 ER - TY - JOUR T1 - Evolving views of disability and public health: The roles of advocacy and public health AN - 862591192; 201110001 AB - Promoting health, quality of life, and participation of persons with disabilities is a relatively recent development in public health. Its brief history reflects three distinct public health perspectives toward disability-a traditional approach that focuses on preventing disability, a contemporary approach that regards disability as a minority group experiencing disparities relative to people without disabilities, and an emerging perspective where disability status is considered one of multiple determinants of health. The field of disability and health has been influenced by the interaction of disability advocacy with the public health process of surveillance, epidemiology research, and intervention. Advocacy draws on political and legal arguments to press for action on issues such as health care access, control of services, and choice of residence. Public health uses surveillance to document magnitude of problems; epidemiology to identify specific groups, develop measures, and apply rigorous research methods; and intervention to improve health behaviors and health outcomes. The field of disability and public health, however, has lagged in addressing the role of environmental factors in the disabling process, in moving to societal participation as an outcome, and in implementing population scale interventions. [Copyright Elsevier Inc.] JF - Disability and Health Journal AU - Krahn, Gloria AU - Campbell, Vincent A AD - Centers for Disease Control and Prevention, National Center on Birth Defects and Developmental Disabilities, Atlanta, GA 30333, USA Y1 - 2011/01// PY - 2011 DA - January 2011 SP - 12 EP - 18 PB - Elsevier Inc., New York NY VL - 4 IS - 1 SN - 1936-5674, 1936-5674 KW - Disability KW - Public health KW - Disability and health KW - Advocacy KW - Models KW - Future directions KW - Disparities KW - Determinants of health KW - Health inequalities KW - Epidemiology KW - Surveillance KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/862591192?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Disability+and+Health+Journal&rft.atitle=Evolving+views+of+disability+and+public+health%3A+The+roles+of+advocacy+and+public+health&rft.au=Krahn%2C+Gloria%3BCampbell%2C+Vincent+A&rft.aulast=Krahn&rft.aufirst=Gloria&rft.date=2011-01-01&rft.volume=4&rft.issue=1&rft.spage=12&rft.isbn=&rft.btitle=&rft.title=Disability+and+Health+Journal&rft.issn=19365674&rft_id=info:doi/10.1016%2Fj.dhjo.2010.05.005 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2011-04-18 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Disability; Public health; Advocacy; Epidemiology; Surveillance; Health inequalities DO - http://dx.doi.org/10.1016/j.dhjo.2010.05.005 ER - TY - JOUR T1 - Low secondary transmission of 2009 pandemic influenza A (H1N1) in households following an outbreak at a summer camp: relationship to timing of exposure AN - 856765771; 14030078 AB - Following an outbreak of 2009 pandemic influenza A (H1N1) at a residential summer camp for boys aged 10-16 years, we assessed secondary household transmission of the novel virus after their return home. Of 212 study participants who attended camp, 49 had confirmed or probable influenza for a primary attack rate of 23%. Of 87 exposed household contacts who did not attend camp, only three instances of probable transmission were observed, for a household secondary attack rate of 3.5%. All secondary cases occurred in households where the ill camp attendee returned home 1 day after onset of illness, with an attack rate of 14.3% in household contacts in this category. Returning home after peak infectivity to others and advanced warning prior to reintegration of sick individuals into the household probably contributed to the overall low secondary attack rate observed. JF - Epidemiology and Infection AU - Doyle, T J AU - Hopkins, R S AD - Florida Department of Health, Tallahassee, Florida, USA, tdoyle@cdc.gov Y1 - 2011/01// PY - 2011 DA - Jan 2011 SP - 45 EP - 51 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU UK VL - 139 IS - 1 SN - 0950-2688, 0950-2688 KW - Virology & AIDS Abstracts; Toxicology Abstracts KW - pandemics KW - Infectivity KW - Influenza A KW - Cyclic AMP KW - Disease transmission KW - X 24490:Other KW - V 22310:Genetics, Taxonomy & Structure UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/856765771?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Low+secondary+transmission+of+2009+pandemic+influenza+A+%28H1N1%29+in+households+following+an+outbreak+at+a+summer+camp%3A+relationship+to+timing+of+exposure&rft.au=Doyle%2C+T+J%3BHopkins%2C+R+S&rft.aulast=Doyle&rft.aufirst=T&rft.date=2011-01-01&rft.volume=139&rft.issue=1&rft.spage=45&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS095026881000141X LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-03-01 N1 - Number of references - 9 N1 - Last updated - 2013-07-26 N1 - SubjectsTermNotLitGenreText - Infectivity; pandemics; Influenza A; Cyclic AMP; Disease transmission DO - http://dx.doi.org/10.1017/S095026881000141X ER - TY - JOUR T1 - Gaps Remain In China's Ability To Detect Emerging Infectious Diseases Despite Advances Since The Onset Of SARS And Avian Flu AN - 856398658; 2011-50294 AB - Early detection of emerging infections in China is critical to the health of the 1.3 billion Chinese people and to the world. China's surveillance system for endemic infectious diseases has improved greatly since 2003, but the country's ability to conduct surveillance for laboratory-confirmed infections remains underdeveloped. This is dangerous for China, the world's most populous country, which has been the focus of global attention since outbreaks of severe acute respiratory syndrome (SARS) and avian influenza. We describe China's public health advances since the 2003 SARS outbreak and conclude that China must now invest far more in pathogen-based surveillance. An enhanced disease-detection system in China will help prevent and contain outbreaks before they cause substantial illness and death in China and other countries. Adapted from the source document. JF - Health Affairs AU - Feng, Zijian AU - Li, Wenkai AU - Varma, Jay K AD - Office of Disease Control and Emergency Response, Chinese Center for Disease Control and Prevention, Beijing Y1 - 2011/01// PY - 2011 DA - January 2011 SP - 127 EP - 135 PB - Project HOPE, Bethesda MD VL - 30 IS - 1 SN - 0278-2715, 0278-2715 KW - Health conditions and policy - Medicine and health care KW - Health conditions and policy - Health and health policy KW - Health conditions and policy - Diseases and disorders KW - Agriculture and agricultural policy - Livestock, meat, and animal products industry KW - Law and ethics - Criminal law KW - Government - Internal security KW - Epidemiology KW - Severe acute respiratory syndrome KW - Communicable diseases KW - Avian influenza KW - China (People's Republic) KW - Surveillance KW - Public health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/856398658?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+Affairs&rft.atitle=Gaps+Remain+In+China%27s+Ability+To+Detect+Emerging+Infectious+Diseases+Despite+Advances+Since+The+Onset+Of+SARS+And+Avian+Flu&rft.au=Feng%2C+Zijian%3BLi%2C+Wenkai%3BVarma%2C+Jay+K&rft.aulast=Feng&rft.aufirst=Zijian&rft.date=2011-01-01&rft.volume=30&rft.issue=1&rft.spage=127&rft.isbn=&rft.btitle=&rft.title=Health+Affairs&rft.issn=02782715&rft_id=info:doi/10.1377%2Fhlthaff.2010.0606 LA - English DB - PAIS Index N1 - Date revised - 2011-03-07 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - China (People's Republic); Epidemiology; Public health; Severe acute respiratory syndrome; Avian influenza; Surveillance; Communicable diseases DO - http://dx.doi.org/10.1377/hlthaff.2010.0606 ER - TY - JOUR T1 - Factors affecting coal particle ignition under oxyfuel combustion atmospheres AN - 1671226096; 13997199 AB - A set of 13 coals of different rank has been tested for ignition propensity in a 20-L explosion chamber simulating oxyfuel combustion gas conditions. Their char residues were also analysed thermogravimetrically. The effects of coal type, coal concentration (from 100 to 600 g/m super(3)), O sub(2) in CO sub(2) atmospheres (up to 40% v/v) and particle size were investigated. The higher rank coals were significantly more difficult to ignite and mostly required higher energy chemical igniters (1000 or 2500 J) whereas the lower rank coals could be ignited with a 500 J igniter even at low coal dust concentrations. The minimum explosibility limit/ignition concentration in air varied slightly around a value of 200 g/m super(3), a little higher for low volatile coals and a little lower for high volatile coals. The ignition limit changed significantly, however, with O sub(2) concentration in CO sub(2), where coals required more oxygen to ignite. Most coals failed to ignite at all in 21% v/v O sub(2) in CO sub(2), but an increase to 30 or 35% v/v O sub(2) gave ignition patterns similar to those in air. In addition, the minimum ignition concentration decreased with increase in O sub(2). However, a further increase to 40% v/v O sub(2) did not generally affect the minimum ignition concentration. Particle size had a non-linear effect on coal ignition. The fine particles (53 km) was generally more difficult to ignite and exhibited a much lower weight loss. JF - Fuel AU - Man, C K AU - Gibbins, J R AD - Department of Mechanical Engineering, Imperial College London, Exhibition Road, London SW7 2AZ, UK cman@cdc.gov Y1 - 2011/01// PY - 2011 DA - January 2011 SP - 294 EP - 304 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 90 IS - 1 SN - 0016-2361, 0016-2361 KW - Mechanical & Transportation Engineering Abstracts (MT); Environmental Engineering Abstracts (EN); ANTE: Abstracts in New Technologies and Engineering (AN); Aerospace & High Technology Database (AH) KW - Oxyfuel combustion KW - Coal ignition KW - CO2 KW - Carbon capture KW - Deflagration KW - Particle size KW - Ignition KW - Igniters KW - Atmospheres KW - Coal KW - Carbon dioxide KW - Explosions KW - Combustion KW - Yes:(AN) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1671226096?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvironmentalengabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Fuel&rft.atitle=Factors+affecting+coal+particle+ignition+under+oxyfuel+combustion+atmospheres&rft.au=Man%2C+C+K%3BGibbins%2C+J+R&rft.aulast=Man&rft.aufirst=C&rft.date=2011-01-01&rft.volume=90&rft.issue=1&rft.spage=294&rft.isbn=&rft.btitle=&rft.title=Fuel&rft.issn=00162361&rft_id=info:doi/10.1016%2Fj.fuel.2010.09.006 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-01 N1 - Last updated - 2016-05-18 DO - http://dx.doi.org/10.1016/j.fuel.2010.09.006 ER - TY - JOUR T1 - The bioavailability of selenium and risk assessment for human selenium poisoning in Se-high areas, China AN - 1039339503; 2012-081262 AB - Enshi, China, is one of the selenosis areas in the world, where sporadic cases of selenium (Se) poisoning in livestock and human were still being found at present. However, selenium bioavailibility in soils and current situation on intake of Se by human have not been reported in detail. In this study, selenium levels and its speciation in water and cropland soils, Se content in crops from Enshi were investigated, as well as estimating the daily intake of Se by local residents. Results showed that the geometric mean of Se concentration was 54.2 mu g/L (2.0-519.3 mu g/L, n=62) and 6.2 mg/kg (2.67-87.3 mg/kg, n=37) in water and soils, respectively. Selenium content ranged from 0.18 mg/kg to 37.1 mg/kg in crops, which was dependent on crop species and Se bioavailability in soils. On the basis of consumption and Se contents of foods, cereal consumption is the major pathway of Se intake by local residents, followed by vegetables, meats, and drinking water. The total daily intake of Se was approximately 3000 mg/day for human in Se-high areas in Enshi, which was considerably higher than the upper tolerable nutrient levels (UL, 400 mg/day) referred by WHO and US EPA, suggesting that a high risk for human chronic Se poisoning still exists in this areas. Furthermore, the daily Se intake through drinking water (108.4 mu g/day) was up to 27.1% of referred Se UL. Thus, unlike previous studies, it is should not ignore the contribution of Se in drinking water when assessing the health risk for human daily intake of Se in Se-high areas. Local residents should be advised to avoid planting crops in areas with Se-high soils or irrigated by Se-high water, and to consume foods mixed with the exotic. The study was supported by the Knowledge Innovation Program of the Chinese Academy of Sciences (KZCX2-YW-JC101), and the National Natural Science Foundation of China (40973085, 40721002, 40573050). JF - Mineralogical Magazine AU - Qin, H B AU - Zhu, J M AU - Su, H AU - Anonymous Y1 - 2011 PY - 2011 DA - 2011 SP - 1679 PB - Mineralogical Society, London VL - 75 IS - 3 SN - 0026-461X, 0026-461X KW - soils KW - Hubei China KW - Far East KW - selenium KW - pollutants KW - human activity KW - agriculture KW - pollution KW - bioavailability KW - drinking water KW - ground water KW - Enshi China KW - soil pollution KW - risk assessment KW - Asia KW - water pollution KW - China KW - public health KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1039339503?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Mineralogical+Magazine&rft.atitle=The+bioavailability+of+selenium+and+risk+assessment+for+human+selenium+poisoning+in+Se-high+areas%2C+China&rft.au=Qin%2C+H+B%3BZhu%2C+J+M%3BSu%2C+H%3BAnonymous&rft.aulast=Qin&rft.aufirst=H&rft.date=2011-01-01&rft.volume=75&rft.issue=3&rft.spage=1679&rft.isbn=&rft.btitle=&rft.title=Mineralogical+Magazine&rft.issn=0026461X&rft_id=info:doi/ L2 - http://minmag.geoscienceworld.org/content/75/3/1679.full.pdf+html http://www.minersoc.org/pages/e_journals/minmag.html LA - English DB - GeoRef N1 - Conference title - Goldschmidt2011 N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Abstract, Copyright, Mineralogical Society of Great Britain and Ireland N1 - Date revised - 2012-01-01 N1 - Last updated - 2012-09-14 N1 - SubjectsTermNotLitGenreText - agriculture; Asia; bioavailability; China; drinking water; Enshi China; Far East; ground water; Hubei China; human activity; pollutants; pollution; public health; risk assessment; selenium; soil pollution; soils; water pollution ER - TY - JOUR T1 - Trends in the Risk for Coronary Heart Disease Among Adults With Diagnosed Diabetes in the U.S.: Findings from the National Health and Nutrition Examination Survey, 1999-2008 AN - 1032900882; 14931608 AB - OBJECTIVE: Coronary heart disease (CHD) is a major cause of mortality among people with diabetes. The objective of this study was to examine the trend in an estimated 10-year risk for developing CHD among adults with diagnosed diabetes in the U.S. RESEARCH DESIGN AND METHODS: Data from 1,977 adults, aged 30-79 years, with diagnosed diabetes who participated in the National Health and Nutrition Examination Survey from 1999-2000 to 2007-2008 were used. Estimated risk was calculated using risk prediction algorithms from the UK Prospective Diabetes Study (UKPDS), the Atherosclerosis Risk in Communities study, and the Framingham Heart Study. RESULTS: Significant improvements in mean HbA1c concentrations, systolic blood pressure, and the ratio of total cholesterol to HDL cholesterol occurred. No significant linear trend for current smoking status was observed. The estimated UKPDS 10-year risk for CHD was 21.1% in 1999-2000 and 16.4% in 2007-2008 (Plinear trend < 0.001). The risk decreased significantly among men, women, whites, African Americans, and Mexican Americans. CONCLUSIONS: The estimated 10-year risk for CHD among adults with diabetes has improved significantly from 1999-2000 to 2007-2008. Sustained efforts in improving risk factors should further benefit the cardiovascular health of people with diabetes. JF - Diabetes Care AU - Ford, Earl S AD - Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia Y1 - 2011 PY - 2011 DA - 2011 SP - 1337 EP - 1343 PB - American Diabetes Association, 1701 N. Beauregard St. Alexandria VA 22311 USA VL - 34 IS - 6 SN - 0149-5992, 0149-5992 KW - Health & Safety Science Abstracts KW - British Isles KW - Diabetes mellitus KW - Prediction KW - Mortality KW - USA KW - Risk factors KW - Research design KW - Cardiovascular diseases KW - Cholesterol KW - Nutrition KW - Ethnic groups KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1032900882?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Diabetes+Care&rft.atitle=Trends+in+the+Risk+for+Coronary+Heart+Disease+Among+Adults+With+Diagnosed+Diabetes+in+the+U.S.%3A+Findings+from+the+National+Health+and+Nutrition+Examination+Survey%2C+1999-2008&rft.au=Ford%2C+Earl+S&rft.aulast=Ford&rft.aufirst=Earl&rft.date=2011-01-01&rft.volume=34&rft.issue=6&rft.spage=1337&rft.isbn=&rft.btitle=&rft.title=Diabetes+Care&rft.issn=01495992&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-08-01 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - Prediction; Diabetes mellitus; Mortality; Risk factors; Research design; Cholesterol; Cardiovascular diseases; Nutrition; Ethnic groups; British Isles; USA ER - TY - JOUR T1 - Unexpected decline in tuberculosis cases coincident with economic recession -- United States, 2009 AN - 1024668987; 16863228 AB - Background: Since 1953, through the cooperation of state and local health departments, the U.S. Centers for Disease Control and Prevention (CDC) has collected information on incident cases of tuberculosis (TB) disease in the United States. In 2009, TB case rates declined -11.4%, compared to an average annual -3.8% decline since 2000. The unexpectedly large decline raised concerns that TB cases may have gone unreported. To address the unexpected decline, we examined trends from multiple sources on TB treatment initiation, medication sales, and laboratory and genotyping data on culture-positive TB. Methods: We analyzed 142,174 incident TB cases reported to the U. S. National Tuberculosis Surveillance System (NTSS) during January 1, 2000-December 31, 2009; TB control program data from 59 public health reporting areas; self-reported data from 50 CDC-funded public health laboratories; monthly electronic prescription claims for new TB therapy prescriptions; and complete genotyping results available for NTSS cases. Accounting for prior trends using regression and time-series analyses, we calculated the deviation between observed and expected TB cases in 2009 according to patient and clinical characteristics, and assessed at what point in time the deviation occurred. Results: The overall deviation in TB cases in 2009 was -7.9%, with -994 fewer cases reported than expected (P < .001). We ruled out evidence of surveillance underreporting since declines were seen in states that used new software for case reporting in 2009 as well as states that did not, and we found no cases unreported to CDC in our examination of over 5400 individual line-listed reports in 11 areas. TB cases decreased substantially among both foreign-born and U.S.-born persons. The unexpected decline began in late 2008 or early 2009, and may have begun to reverse in late 2009. The decline was greater in terms of case counts among foreign-born than U.S.-born persons; among the foreign-born, the declines were greatest in terms of percentage deviation from expected among persons who had been in the United States less than 2 years. Among U.S.-born persons, the declines in percentage deviation from expected were greatest among homeless persons and substance users. Independent information systems (NTSS, TB prescription claims, and public health laboratories) reported similar patterns of declines. Genotyping data did not suggest sudden decreases in recent transmission. Conclusions: Our assessments show that the decline in reported TB was not an artifact of changes in surveillance methods; rather, similar declines were found through multiple data sources. While the steady decline of TB cases before 2009 suggests ongoing improvement in TB control, we were not able to identify any substantial change in TB control activities or TB transmission that would account for the abrupt decline in 2009. It is possible that other multiple causes coincident with economic recession in the United States, including decreased immigration and delayed access to medical care, could be related to TB declines. Our findings underscore important needs in addressing health disparities as we move towards TB elimination in the United States. JF - BMC Public Health AU - Winston, Carla A AU - Navin, Thomas R AU - Becerra, Jose E AU - Chen, Michael P AU - Armstrong, Lori R AU - Jeffries, Carla AU - Yelk Woodruff, Rachel S AU - Wing, Jessie AU - Starks, Angela M AU - Hales, Craig M AU - Kammerer, J Steve AU - Mac Kenzie, William R AU - Mitruka, Kiren AU - Miner, Mark C AU - Price, Sandy AU - Scavotto, Joseph AU - Cronin, Ann M AU - Griffin, Phillip AU - LoBue, Philip A AU - Castro, Kenneth G AD - Division of Tuberculosis Elimination, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA, 30333 USA Y1 - 2011 PY - 2011 DA - 2011 SP - 846 PB - BioMed Central Ltd., Middlesex House London W1T 4LB United Kingdom VL - 11 IS - 1 SN - 1471-2458, 1471-2458 KW - Health & Safety Science Abstracts; Microbiology Abstracts B: Bacteriology KW - Data processing KW - Immigration KW - Mycobacterium KW - Genotyping KW - Control programs KW - Cooperation KW - Disease control KW - Time series analysis KW - Public health KW - Computer programs KW - USA KW - software KW - Economics KW - homelessness KW - Tuberculosis KW - Ethnic groups KW - Information systems KW - H 12000:Epidemiology and Public Health KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1024668987?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=BMC+Public+Health&rft.atitle=Unexpected+decline+in+tuberculosis+cases+coincident+with+economic+recession+--+United+States%2C+2009&rft.au=Winston%2C+Carla+A%3BNavin%2C+Thomas+R%3BBecerra%2C+Jose+E%3BChen%2C+Michael+P%3BArmstrong%2C+Lori+R%3BJeffries%2C+Carla%3BYelk+Woodruff%2C+Rachel+S%3BWing%2C+Jessie%3BStarks%2C+Angela+M%3BHales%2C+Craig+M%3BKammerer%2C+J+Steve%3BMac+Kenzie%2C+William+R%3BMitruka%2C+Kiren%3BMiner%2C+Mark+C%3BPrice%2C+Sandy%3BScavotto%2C+Joseph%3BCronin%2C+Ann+M%3BGriffin%2C+Phillip%3BLoBue%2C+Philip+A%3BCastro%2C+Kenneth+G&rft.aulast=Winston&rft.aufirst=Carla&rft.date=2011-01-01&rft.volume=11&rft.issue=1&rft.spage=846&rft.isbn=&rft.btitle=&rft.title=BMC+Public+Health&rft.issn=14712458&rft_id=info:doi/10.1186%2F1471-2458-11-846 L2 - http://www.biomedcentral.com/1471-2458/11/846 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-07-01 N1 - Number of references - 18 N1 - Last updated - 2013-06-28 N1 - SubjectsTermNotLitGenreText - Computer programs; software; Immigration; Data processing; Cooperation; Control programs; Genotyping; Economics; Disease control; Tuberculosis; Information systems; Public health; homelessness; Time series analysis; Ethnic groups; Mycobacterium; USA DO - http://dx.doi.org/10.1186/1471-2458-11-846 ER - TY - JOUR T1 - Type 2 vaccine-derived poliovirus from patients with acute flaccid paralysis in china: current immunization strategy effectively prevented its sustained transmission. AN - 815960858; 21050127 AB - In China, 5 patients with acute flaccid paralysis (AFP) associated with type 2 vaccine-derived poliovirus (VDPV) were identified by an AFP surveillance system from 1996 through 2009. A maximum-likelihood tree shows that all 5 Chinese VDPVs were independent. These 5 VDPVs were 100-216 d old according to the number of synonymous substitutions per synonymous site and 176-292 d old according to the number of substitutions per site. This result indicates limited virus replication since the administration of the initiating oral polio vaccine (OPV) dose, which is consistent with the rapid evolution rate of poliovirus genomes. The above-mentioned VDPVs have important implications in the global polio eradication initiative. Localized, limited, and transient circulation may be typical of OPVs; hence, independent VDPVs could be found because of the large population and excellent surveillance system, which permitted early detection and response, but sustained transmission was limited because of high population immunity. JF - The Journal of infectious diseases AU - Zhang, Yong AU - Yan, Dongmei AU - Zhu, Shuangli AU - Wen, Ning AU - Li, Li AU - Wang, Haiyan AU - Liu, Jianfeng AU - Ye, Xufang AU - Ding, Zhengrong AU - Wang, Dongyan AU - Zhu, Hui AU - Chen, Li AU - Hou, Xiaohui AU - An, Hongqiu AU - Liang, Xiaofeng AU - Luo, Huiming AU - Kew, Olen AU - Xu, Wenbo AD - World Health Organization Western Pacific Regional Polio Reference Laboratory and State Key Laboratory for Molecular Virology and Genetic Engineering, Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing. Y1 - 2010/12/15/ PY - 2010 DA - 2010 Dec 15 SP - 1780 EP - 1788 VL - 202 IS - 12 KW - Poliovirus Vaccine, Oral KW - 0 KW - RNA, Viral KW - Abridged Index Medicus KW - Index Medicus KW - Phylogeny KW - Humans KW - Child KW - Sequence Homology KW - Sequence Analysis, DNA KW - Child, Preschool KW - Infant KW - Molecular Epidemiology KW - China -- epidemiology KW - Point Mutation KW - Molecular Sequence Data KW - RNA, Viral -- genetics KW - Adolescent KW - Cluster Analysis KW - Female KW - Male KW - Prevalence KW - Poliovirus -- classification KW - Poliomyelitis -- virology KW - Poliomyelitis -- prevention & control KW - Poliovirus Vaccine, Oral -- immunology KW - Poliovirus -- genetics KW - Immunization -- methods KW - Poliomyelitis -- epidemiology KW - Poliovirus Vaccine, Oral -- adverse effects KW - Poliovirus -- immunology KW - Poliomyelitis -- pathology KW - Poliovirus -- isolation & purification UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/815960858?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+infectious+diseases&rft.atitle=Type+2+vaccine-derived+poliovirus+from+patients+with+acute+flaccid+paralysis+in+china%3A+current+immunization+strategy+effectively+prevented+its+sustained+transmission.&rft.au=Zhang%2C+Yong%3BYan%2C+Dongmei%3BZhu%2C+Shuangli%3BWen%2C+Ning%3BLi%2C+Li%3BWang%2C+Haiyan%3BLiu%2C+Jianfeng%3BYe%2C+Xufang%3BDing%2C+Zhengrong%3BWang%2C+Dongyan%3BZhu%2C+Hui%3BChen%2C+Li%3BHou%2C+Xiaohui%3BAn%2C+Hongqiu%3BLiang%2C+Xiaofeng%3BLuo%2C+Huiming%3BKew%2C+Olen%3BXu%2C+Wenbo&rft.aulast=Zhang&rft.aufirst=Yong&rft.date=2010-12-15&rft.volume=202&rft.issue=12&rft.spage=1780&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+infectious+diseases&rft.issn=1537-6613&rft_id=info:doi/10.1086%2F657410 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-12-13 N1 - Date created - 2010-11-18 N1 - Date revised - 2017-01-13 N1 - Genetic sequence - HM107832; GENBANK; HM107833; HM107834; HM107835; AY948201 N1 - SuppNotes - Comment In: J Infect Dis. 2011 Jun 15;203(12):1875; author reply 1875-6 [21606545] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1086/657410 ER - TY - JOUR T1 - Biosafety and biosecurity as essential pillars of international health security and cross-cutting elements of biological nonproliferation AN - 858421349; 14230987 AB - The critical aspects of biosafety, biosecurity, and biocontainment have been in the spotlight in recent years. There have also been increased international efforts to improve awareness of modern practices and concerns with regard to the safe pursuit of life sciences research, and to optimize current oversight frameworks, thereby resulting in decreased risk of terrorist/malevolent acquisition of deadly pathogens or accidental release of a biological agent, and increased safety of laboratory workers. Our purpose is to highlight how the World Health Organization's (WHO) revised International Health Regulations (IHR[2005]), the Biological Weapons Convention (BWC), and the United Nations Security Council Resolution (UNSCR) 1540 overlap in their requirements with regard to biosafety and biosecurity in order to improve the understanding of practitioners and policymakers and maximize the use of national resources employed to comply with internationally-mandated requirements. The broad range of goals of these international instruments, which are linked by the common thread of biosafety and biosecurity, highlight their significance as essential pillars of international health security and cross-cutting elements of biological nonproliferation. The current efforts of the Republic of Georgia to enhance biosafety and biosecurity in accordance with these international instruments are summarized. JF - BMC Public Health AU - Bakanidze, Lela AU - Imnadze, Paata AU - Perkins, Dana AD - National Center for Disease Control and Public Health of Georgia, Tbilisi, Georgia Y1 - 2010/12/03/ PY - 2010 DA - 2010 Dec 03 SP - S12 PB - BioMed Central Ltd., Middlesex House London W1T 4LB UK VL - 10 IS - 1 KW - Physical Education Index; Risk Abstracts; Health & Safety Science Abstracts KW - terrorism KW - security KW - International health KW - Public health KW - Health (organization) KW - Recruiting KW - United Nations KW - Terrorism KW - Safety KW - Pathogens KW - Councils KW - Security KW - Weapons KW - councils KW - Georgia KW - International regulations KW - H 13000:Medical Safety KW - R2 23060:Medical and environmental health KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/858421349?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=BMC+Public+Health&rft.atitle=Biosafety+and+biosecurity+as+essential+pillars+of+international+health+security+and+cross-cutting+elements+of+biological+nonproliferation&rft.au=Bakanidze%2C+Lela%3BImnadze%2C+Paata%3BPerkins%2C+Dana&rft.aulast=Bakanidze&rft.aufirst=Lela&rft.date=2010-12-03&rft.volume=10&rft.issue=1&rft.spage=S12&rft.isbn=&rft.btitle=&rft.title=BMC+Public+Health&rft.issn=1471-2458&rft_id=info:doi/10.1186%2F1471-2458-10-S1-S12 LA - English DB - Physical Education Index; ProQuest Environmental Science Collection N1 - Date revised - 2011-03-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Health (organization); Safety; Recruiting; International health; Public health; Security; terrorism; Weapons; Terrorism; councils; International regulations; Pathogens; United Nations; security; Councils; Georgia DO - http://dx.doi.org/10.1186/1471-2458-10-S1-S12 ER - TY - JOUR T1 - Cigarette Smoking Women of Reproductive Age Who Use Oral Contraceptives: Results from the 2002 and 2004 Behavioral Risk Factor Surveillance Systems AN - 899133116; 13994536 AB - Despite health warnings about the increased risk of cerebrovascular disease among women who smoke while using oral contraceptives (OCs), prior research suggests that OC use is still prevalent among women who smoke cigarettes. Our objective was to investigate the prevalence of OC use among cigarette smoking women of reproductive age in the United States. Study Design: We extracted data from the 2002 and 2004 Behavioral Risk Factor Surveillance System surveys of 76,544 women between 18 and 44 years of age who reported using some form of contraception. OC use, or self-reported use of "the pill," was examined among those who currently smoke, either everyday or some days. Multivariable logistic regression models were used to compare OC use between smoking and nonsmoking women. Results: One fourth (26.9%) of U.S. women who smoke compared with 34.6% of nonsmoking women reported currently using OCs. After adjusting for age, race/ethnicity, marital status, education level, binge drinking, and health care coverage, women who smoke were 0.6 (95% confidence interval [CI], 0.6-0.7) times as likely to use OCs as nonsmoking women. Among women aged 35 to 44 years, the odds of OC use among smokers was even further reduced (odds ratio [OR], 0.3; 95% CI, 0.3-0.4) compared with nonsmokers. Conclusion: Among U.S. women of reproductive age who use contraception, particularly among women aged 35 to 44 years, those who smoke cigarettes are significantly less likely to use OCs than those who do not. JF - Women's Health Issues AU - McClave, Annette K AU - Hogue, Carol J AU - Huber, Larissa RBrunner AU - Ehrlich, Alexandra C AD - Office on Smoking and Health, Centers for Disease Control and Prevention, Atlanta, Georgia, AMcClave@cdc.gov Y1 - 2010/12// PY - 2010 DA - Dec 2010 SP - 380 EP - 385 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 20 IS - 6 SN - 1049-3867, 1049-3867 KW - Toxicology Abstracts; Risk Abstracts KW - Drinking KW - Age KW - Data processing KW - Cerebrovascular diseases KW - marriage KW - Contraceptives (oral) KW - binge drinking KW - contraceptives KW - Models KW - Smoke KW - USA KW - Education KW - Health care KW - Contraception KW - Risk factors KW - Cigarette smoking KW - Regression analysis KW - Females KW - Races KW - Ethnic groups KW - X 24380:Social Poisons & Drug Abuse KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/899133116?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Women%27s+Health+Issues&rft.atitle=Cigarette+Smoking+Women+of+Reproductive+Age+Who+Use+Oral+Contraceptives%3A+Results+from+the+2002+and+2004+Behavioral+Risk+Factor+Surveillance+Systems&rft.au=McClave%2C+Annette+K%3BHogue%2C+Carol+J%3BHuber%2C+Larissa+RBrunner%3BEhrlich%2C+Alexandra+C&rft.aulast=McClave&rft.aufirst=Annette&rft.date=2010-12-01&rft.volume=20&rft.issue=6&rft.spage=380&rft.isbn=&rft.btitle=&rft.title=Women%27s+Health+Issues&rft.issn=10493867&rft_id=info:doi/10.1016%2Fj.whi.2010.06.006 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - Drinking; Age; Data processing; Cerebrovascular diseases; Contraceptives (oral); Models; Smoke; Contraception; Risk factors; Cigarette smoking; Regression analysis; Ethnic groups; Races; Education; Health care; Females; marriage; binge drinking; contraceptives; USA DO - http://dx.doi.org/10.1016/j.whi.2010.06.006 ER - TY - JOUR T1 - Predictors of Unprotected Sex Among Female Sex Workers in Madagascar: Comparing Semen Biomarkers and Self-Reported Data AN - 872126531; 14239103 AB - Research on the determinants of condom use and condom non-use generally has relied on self-reported data with questionable validity. We identified predictors of recent, unprotected sex among 331 female sex workers in Madagascar using two outcome measures: self-reports of unprotected sex within the past 48h and detection of prostate-specific antigen (PSA), a biological marker of recent semen exposure. Multivariable logistic regression revealed that self-reported unprotected sex was associated with three factors: younger age, having a sipa (emotional partner) in the prior seven days, and no current use of hormonal contraception. The sole factor related to having PSA detected was prevalent chlamydial infection (adjusted odds ratio, 4.5; 95% confidence interval, 2.0-10.1). Differences in predictors identified suggest that determinants of unprotected sex, based on self-reported behaviors, might not correlate well with risk of semen exposure. Caution must be taken when interpreting self-reported sexual behavior measures or when adjusting for them in analyses evaluating interventions for the prevention of HIV/STIs. JF - AIDS and Behavior AU - Gallo, Maria F AU - Steiner, Markus J AU - Hobbs, Marcia M AU - Weaver, Mark A AU - Hoke, Theresa Hatzell AU - Damme, Kathleen AU - Jamieson, Denise J AU - Macaluso, Maurizio AD - Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA, mgallo@cdc.gov Y1 - 2010/12// PY - 2010 DA - Dec 2010 SP - 1279 EP - 1286 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 14 IS - 6 SN - 1090-7165, 1090-7165 KW - Virology & AIDS Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - Bioindicators KW - sexual behavior KW - Emotions KW - Acquired immune deficiency syndrome KW - Age KW - Data processing KW - Prostitution KW - Infection KW - prostate-specific antigen KW - Sexual behavior KW - biomarkers KW - Condoms KW - Contraception KW - Human immunodeficiency virus KW - ISW, Indian Ocean, Madagascar KW - intervention KW - condoms KW - infection KW - prevention KW - Semen KW - Females KW - Occupational exposure KW - Sex KW - V 22360:AIDS and HIV KW - H 1000:Occupational Safety and Health KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/872126531?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Predictors+of+Unprotected+Sex+Among+Female+Sex+Workers+in+Madagascar%3A+Comparing+Semen+Biomarkers+and+Self-Reported+Data&rft.au=Gallo%2C+Maria+F%3BSteiner%2C+Markus+J%3BHobbs%2C+Marcia+M%3BWeaver%2C+Mark+A%3BHoke%2C+Theresa+Hatzell%3BDamme%2C+Kathleen%3BJamieson%2C+Denise+J%3BMacaluso%2C+Maurizio&rft.aulast=Gallo&rft.aufirst=Maria&rft.date=2010-12-01&rft.volume=14&rft.issue=6&rft.spage=1279&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-010-9742-8 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-06-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Emotions; Age; Data processing; Prostitution; Infection; biomarkers; Sexual behavior; prostate-specific antigen; Condoms; Contraception; Semen; Occupational exposure; Sex; Bioindicators; sexual behavior; Acquired immune deficiency syndrome; Human immunodeficiency virus; intervention; prevention; infection; condoms; Females; ISW, Indian Ocean, Madagascar DO - http://dx.doi.org/10.1007/s10461-010-9742-8 ER - TY - JOUR T1 - FKS Mutations and Elevated Echinocandin MIC Values among Candida glabrata Isolates from U.S. Population-Based Surveillance AN - 864951992; 14036332 AB - Candida glabrata is the second leading cause of candidemia in the United States. Its high-level resistance to triazole antifungal drugs has led to the increased use of the echinocandin class of antifungal agents for primary therapy of these infections. We monitored C. glabrata bloodstream isolates from a population-based surveillance study for elevated echinocandin MIC values (MICs of 0.25 mu g/ml). From the 490 C. glabrata isolates that were screened, we identified 16 isolates with an elevated MIC value (2.9% of isolates from Atlanta and 2.0% of isolates from Baltimore) for one or more of the echinocandin drugs caspofungin, anidulafungin, and micafungin. All of the isolates with elevated MIC values had a mutation in the previously identified hot spot 1 of either the glucan synthase FKS1 (n = 2) or FKS2 (n = 14) gene. No mutations were detected in hot spot 2 of either FKS1 or FKS2. The predominant mutation was mutation of FKS2-encoded serine 663 to proline (S663P), found in 10 of the isolates with elevated echinocandin MICs. Two of the mutations, R631G for FKS1 and R665G for FKS2, have not been reported previously for C. glabrata. Multilocus sequence typing indicated that the predominance of the S663P mutation was not due to the clonal spread of a single sequence type. With a rising number of echinocandin therapy failures reported, it is important to continue to monitor rates of elevated echinocandin MIC values and the associated mutations. JF - Antimicrobial Agents & Chemotherapy AU - Zimbeck, Alicia J AU - Iqbal, Naureen AU - Ahlquist, Angela M AU - Farley, Monica M AU - Harrison, Lee H AU - Chiller, Tom AU - Lockhart, Shawn R AD - Mycotic Disease Branch, Centers for Disease Control and Prevention, gyi2@cdc.gov Y1 - 2010/12// PY - 2010 DA - Dec 2010 SP - 5042 EP - 5047 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 54 IS - 12 SN - 0066-4804, 0066-4804 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts C: Algology, Mycology & Protozoology KW - Proline KW - Antifungal agents KW - Candidemia KW - micafungin KW - Candida glabrata KW - Caspofungin KW - Infection KW - Minimum inhibitory concentration KW - multilocus sequence typing KW - triazoles KW - echinocandins KW - Drugs KW - Mutation KW - glucans KW - Serine KW - A 01380:Plant Protection, Fungicides & Seed Treatments KW - K 03310:Genetics & Taxonomy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/864951992?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=FKS+Mutations+and+Elevated+Echinocandin+MIC+Values+among+Candida+glabrata+Isolates+from+U.S.+Population-Based+Surveillance&rft.au=Zimbeck%2C+Alicia+J%3BIqbal%2C+Naureen%3BAhlquist%2C+Angela+M%3BFarley%2C+Monica+M%3BHarrison%2C+Lee+H%3BChiller%2C+Tom%3BLockhart%2C+Shawn+R&rft.aulast=Zimbeck&rft.aufirst=Alicia&rft.date=2010-12-01&rft.volume=54&rft.issue=12&rft.spage=5042&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.00836-10 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-05-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Antifungal agents; Proline; Candidemia; micafungin; Caspofungin; Infection; Minimum inhibitory concentration; multilocus sequence typing; triazoles; echinocandins; Mutation; Drugs; Serine; glucans; Candida glabrata DO - http://dx.doi.org/10.1128/AAC.00836-10 ER - TY - JOUR T1 - Cytotoxicity of eight cigarette smoke condensates in three test systems: Comparisons between assays and condensates AN - 856774072; 14198032 AB - Cytotoxic properties of tobacco smoke are associated with chronic tobacco-related diseases. The cytotoxicity of tobacco smoke can be tested with short-term predictive assays. In this study, we compare eight mainstream cigarette smoke condensates (CSCs) from commercial and experimental cigarettes in three different cytotoxicity assays with unique and overlapping endpoints. The CSCs demonstrated cytotoxicity in all assays. In the multiple cytotoxicity endpoint (MCE) assay with TK-6 cells, the cigarette varieties that had the highest EC50s for reduced cell growth also showed a positive dose-response relationship for necrotic cells. In the IdMOC multiple cell-type co-culture (MCTCC) system, all CSCs reduced the viability of the cells. Low concentrations of some CSCs had a stimulatory effect in lung microvascular endothelial cells and small airway epithelial cells. In the neutral dye assay (NDA), except for a 100% flue-cured tobacco CSC, there was little consistency between CSCs producing morphological evidence of moderate or greater toxicity and the CSCs with the lowest EC50s in the MCE or MCTCC assays. Overall, cigarettes made with flue-cured tobacco were the most cytotoxic across the assays. When results were expressed on a per-mg of nicotine basis, lower tar cigarettes were the most cytotoxic in primary human respiratory cells. JF - Regulatory Toxicology and Pharmacology AU - Richter, Patricia A AU - Li, Albert P AU - Polzin, Gregory AU - Roy, Shambhu K AD - Office on Smoking and Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, Mailstop K-50, Atlanta, GA 30341-3724, USA Y1 - 2010/12// PY - 2010 DA - Dec 2010 SP - 428 EP - 436 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 58 IS - 3 SN - 0273-2300, 0273-2300 KW - Environment Abstracts; Toxicology Abstracts KW - Epithelial cells KW - Microvasculature KW - Cigarettes KW - Tar KW - Assays KW - Cigarette smoke KW - Toxicity KW - Smoke KW - Endothelial cells KW - Cytotoxicity KW - Condensates KW - Lung KW - Nicotine KW - Dose-response effects KW - Tobacco KW - Respiratory tract KW - X 24380:Social Poisons & Drug Abuse KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/856774072?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Regulatory+Toxicology+and+Pharmacology&rft.atitle=Cytotoxicity+of+eight+cigarette+smoke+condensates+in+three+test+systems%3A+Comparisons+between+assays+and+condensates&rft.au=Richter%2C+Patricia+A%3BLi%2C+Albert+P%3BPolzin%2C+Gregory%3BRoy%2C+Shambhu+K&rft.aulast=Richter&rft.aufirst=Patricia&rft.date=2010-12-01&rft.volume=58&rft.issue=3&rft.spage=428&rft.isbn=&rft.btitle=&rft.title=Regulatory+Toxicology+and+Pharmacology&rft.issn=02732300&rft_id=info:doi/10.1016%2Fj.yrtph.2010.08.009 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-03-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Microvasculature; Epithelial cells; Cigarettes; Tar; Cigarette smoke; Toxicity; Endothelial cells; Cytotoxicity; Condensates; Nicotine; Lung; Dose-response effects; Tobacco; Respiratory tract; Smoke; Assays DO - http://dx.doi.org/10.1016/j.yrtph.2010.08.009 ER - TY - JOUR T1 - Daily Participation in Sports and Students' Sexual Activity AN - 856399706; 2011-35553 AB - CONTEXT: Previous studies suggest that student athletes may be less likely than nonathletes to engage in sexual behavior. However, few have explored sexual risk behavior among athletes in early adolescence. METHODS: In 2005, a sample of 10,487 students in 26 Los Angeles public middle and high schools completed a self-administered survey that asked about their demographic characteristics, sports participation, sexual behaviors and expectations, and parental relationships. Chi-square analyses compared reported levels of daily participation in sports, experience with intercourse, experience with oral sex and condom use at last intercourse by selected characteristics. Predictors of sexual experience and condom use were assessed in multivariate logistic regression analyses. RESULTS: One-third of students reported daily participation in sports. This group had higher odds of ever having had intercourse and ever having had oral sex than their peers who did not play a sport daily (odds ratios, 1.2 and 1.1, respectively). The increases in risk were greater for middle school sports participants than for their high school counterparts (1.5 and 1.6, respectively). Among sexually experienced students, daily sports participants also had elevated odds of reporting condom use at last intercourse (1.4). CONCLUSIONS: Students as young as middle school age who participate in sports daily may have an elevated risk for STDs and pregnancy. Health professionals should counsel middle school athletes about sexual risk reduction, given that young students may find it particularly difficult to obtain contraceptives, STD testing and prevention counseling. Adapted from the source document. JF - Perspectives on Sexual and Reproductive Health AU - Habel, Melissa A AU - Dittus, Patricia J AU - De Rosa, Christine J AU - Chung, Emily Q AU - Kerndt, Peter R AD - Melissa A. Habel is health scientist, and Patricia J. Dittus is behavioral scientist- both with the National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, Division of STD Prevention, Behavioral Interventions and Research Branch, Centers for Disease Control and Prevention, Atlanta. Y1 - 2010/12// PY - 2010 DA - December 2010 SP - 244 EP - 250 PB - Alan Guttmacher Institute, New York, NY VL - 42 IS - 4 SN - 1538-6341, 1538-6341 KW - Social conditions and policy - Sports KW - Social conditions and policy - Sex KW - Education and education policy - Education personnel and population KW - Social conditions and policy - Public safety and security KW - Social conditions and policy - Marriage and family life KW - Population groups, population policy, and demographics - Family planning KW - Social conditions and policy - Psychology KW - Condoms KW - Los Angeles, California KW - Risk KW - Counseling KW - Parents KW - Students KW - Sexual behavior KW - Contraceptives KW - Demographics KW - School sports KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/856399706?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Perspectives+on+Sexual+and+Reproductive+Health&rft.atitle=Daily+Participation+in+Sports+and+Students%27+Sexual+Activity&rft.au=Habel%2C+Melissa+A%3BDittus%2C+Patricia+J%3BDe+Rosa%2C+Christine+J%3BChung%2C+Emily+Q%3BKerndt%2C+Peter+R&rft.aulast=Habel&rft.aufirst=Melissa&rft.date=2010-12-01&rft.volume=42&rft.issue=4&rft.spage=244&rft.isbn=&rft.btitle=&rft.title=Perspectives+on+Sexual+and+Reproductive+Health&rft.issn=15386341&rft_id=info:doi/10.1363%2F4224410 LA - English DB - PAIS Index N1 - Date revised - 2011-03-07 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - School sports; Sexual behavior; Students; Risk; Los Angeles, California; Demographics; Parents; Condoms; Counseling; Contraceptives DO - http://dx.doi.org/10.1363/4224410 ER - TY - JOUR T1 - Prescription drug laws, drug overdoses, and drug sales in New York and Pennsylvania AN - 853230824; 2011-22165 AB - Drug overdose mortality nearly doubled in the United States from 1999 to 2004, with most of the increase due to prescription drug overdoses. Studying mortality rates in states that did not experience such increases may identify successful prescription overdose prevention strategies. We compared New York, a state that did not experience an overdose increase, with its neighbor, Pennsylvania. New York and Pennsylvania had prescription drug monitoring programs (PDMPs), but New York's PDMP was better funded and made use of serialized, tamperproof prescription forms. Per capita usage of the major prescription opioids in New York was two-thirds that of Pennsylvania. The drug overdose death rate in Pennsylvania was 1.6 times that of New York in 2006. Differences between New York and Pennsylvania might be due to the regulatory environment in New York State. Adapted from the source document. JF - Journal of Public Health Policy AU - Paulozzi, Leonard J AU - Stier, Daniel D AD - Division of Unintentional Injury Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA, USA Y1 - 2010/12// PY - 2010 DA - December 2010 SP - 422 EP - 432 PB - Palgrave Macmillan, Basingstoke UK VL - 31 IS - 4 SN - 0197-5897, 0197-5897 KW - Health conditions and policy - Medicine and health care KW - Manufacturing and heavy industry - Pharmaceutical industry KW - Social conditions and policy - Drinking, smoking, and drug addiction KW - Population groups, population policy, and demographics - Demography and census KW - United States KW - Prescriptions KW - Mortality KW - New York (state) KW - Pennsylvania KW - Drug abuse KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/853230824?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Public+Health+Policy&rft.atitle=Prescription+drug+laws%2C+drug+overdoses%2C+and+drug+sales+in+New+York+and+Pennsylvania&rft.au=Paulozzi%2C+Leonard+J%3BStier%2C+Daniel+D&rft.aulast=Paulozzi&rft.aufirst=Leonard&rft.date=2010-12-01&rft.volume=31&rft.issue=4&rft.spage=422&rft.isbn=&rft.btitle=&rft.title=Journal+of+Public+Health+Policy&rft.issn=01975897&rft_id=info:doi/10.1057%2Fjphp.2010.27 LA - English DB - PAIS Index N1 - Date revised - 2011-02-16 N1 - Last updated - 2016-09-28 N1 - CODEN - JPPODK N1 - SubjectsTermNotLitGenreText - Prescriptions; Drug abuse; New York (state); Pennsylvania; Mortality; United States DO - http://dx.doi.org/10.1057/jphp.2010.27 ER - TY - JOUR T1 - Effectiveness of Policies Maintaining or Restricting Days of Alcohol Sales on Excessive Alcohol Consumption and Related Harms AN - 853230521; 2011-21449 AB - Local, state, and national laws and policies that limit the days of the week on which alcoholic beverages may be sold may be a means of reducing excessive alcohol consumption and related harms. The methods of the Guide to Community Preventive Services were used to synthesize scientific evidence on the effectiveness for preventing excessive alcohol consumption and related harms of laws and policies maintaining or reducing the days when alcoholic beverages may be sold. Outcomes assessed in 14 studies that met qualifying criteria were excessive alcohol consumption and alcohol-related harms, including motor vehicle injuries and deaths, violence-related and other injuries, and health conditions. Qualifying studies assessed the effects of changes in days of sale in both on-premises settings (at which alcoholic beverages are consumed where purchased) and off-premises settings (at which alcoholic beverages may not be consumed where purchased). Eleven studies assessed the effects of adding days of sale, and three studies assessed the effects of imposing a ban on sales on a given weekend day. The evidence from these studies indicated that increasing days of sale leads to increases in excessive alcohol consumption and alcohol-related harms and that reducing the number of days that alcoholic beverages are sold generally decreases alcohol-related harms. Based on these findings, when the expansion of days of sale is being considered, laws and policies maintaining the number of days of the week that alcoholic beverages are sold at on- and off-premises outlets in local, state, and national jurisdictions are effective public health strategies for preventing excessive alcohol consumption and related harms. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Middleton, Jennifer Cook AU - Hahn, Robert A AU - Kuzara, Jennifer L AU - Elder, Randy AU - Brewer, Robert AU - Chattopadhyay, Sajal AU - Fielding, Jonathan AU - Naimi, Timothy S AU - Toomey, Traci AU - Lawrence, Briana AD - c/o Hahn -- Community Guide Branch, CDC, Atlanta, GA Y1 - 2010/12// PY - 2010 DA - December 2010 SP - 575 EP - 589 PB - Elsevier Science, New York NY VL - 39 IS - 6 SN - 0749-3797, 0749-3797 KW - Social conditions and policy - Drinking, smoking, and drug addiction KW - Business and service sector - Markets, marketing, and merchandising KW - Economic conditions and policy - Economic policy, planning, and development KW - Law and ethics - Law and jurisprudence KW - Business and service sector - Business operations, practices, and workplaces KW - Economic conditions and policy - Consumers and consumption KW - Transportation and transportation policy - Roads and land transport KW - Manufacturing and heavy industry - Automotive industry KW - Administration of justice - Courts and judicial power KW - Motor vehicle drivers KW - Sales KW - Alcohol KW - Business hours KW - Jurisdiction KW - Consumption KW - Drinking behavior KW - Regulation KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/853230521?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Effectiveness+of+Policies+Maintaining+or+Restricting+Days+of+Alcohol+Sales+on+Excessive+Alcohol+Consumption+and+Related+Harms&rft.au=Middleton%2C+Jennifer+Cook%3BHahn%2C+Robert+A%3BKuzara%2C+Jennifer+L%3BElder%2C+Randy%3BBrewer%2C+Robert%3BChattopadhyay%2C+Sajal%3BFielding%2C+Jonathan%3BNaimi%2C+Timothy+S%3BToomey%2C+Traci%3BLawrence%2C+Briana&rft.aulast=Middleton&rft.aufirst=Jennifer&rft.date=2010-12-01&rft.volume=39&rft.issue=6&rft.spage=575&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2010.09.015 LA - English DB - PAIS Index N1 - Date revised - 2011-02-16 N1 - Last updated - 2016-09-28 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Alcohol; Drinking behavior; Sales; Regulation; Business hours; Consumption; Motor vehicle drivers; Jurisdiction DO - http://dx.doi.org/10.1016/j.amepre.2010.09.015 ER - TY - JOUR T1 - Tuberculosis deaths averted by implementation of the DOTS strategy in Kazakhstan AN - 839714339; 14092215 AB - SETTING: Kazakhstan began implementing the DOTS strategy for tuberculosis (TB) in 1998. OBJECTIVE: Data were analyzed 1) to determine if changes in TB mortality rate (MR) and case fatality rate (CFR) in Kazakhstan for 1998-2003 differed from those of Uzbekistan and four adjacent Russian Federation (RF) oblasts that had not yet implemented DOTS, and 2) to estimate the number of deaths averted in Kazakhstan as a result of DOTS. DESIGN: Observed MRs were calculated, and predicted MRs for Kazakhstan were approximated by linear regression based on average slope of MRs from 1998 through 2003 in adjacent non-DOTS-implementing territories. Deaths averted were calculated by comparing predicted MRs to actual MRs by converting rate differences to numbers of deaths. RESULTS: TB MRs in Kazakhstan decreased markedly, but remained stable or increased in the neighboring territories. CFRs decreased markedly in Kazakhstan and marginally in Uzbekistan, and increased in the neighboring RF oblasts. From 1998 to 2004, DOTS appears to have helped avert approximately 17800 deaths in Kazakhstan. CONCLUSION: DOTS has contributed markedly to a decrease in TB mortality in Kazakhstan. In settings where mortality data are relatively complete, deaths averted can be another indicator of DOTS effectiveness. JF - International Journal of Tuberculosis and Lung Disease AU - Favorov, M AU - Belilovsky, E AU - Aitmagambetova, I AU - Ismailov, S AU - White, ME AU - Chorba, T AD - National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Mailstop: E-07, Atlanta, GA 30333, USA, tlc2@cdc.gov Y1 - 2010/12// PY - 2010 DA - Dec 2010 SP - 1582 EP - 1588 PB - International Union Against Tuberculosis and Lung Disease VL - 14 IS - 12 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology KW - Mortality KW - Data processing KW - Mycobacterium KW - Lung diseases KW - Tuberculosis KW - Territory KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839714339?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Tuberculosis+deaths+averted+by+implementation+of+the+DOTS+strategy+in+Kazakhstan&rft.au=Favorov%2C+M%3BBelilovsky%2C+E%3BAitmagambetova%2C+I%3BIsmailov%2C+S%3BWhite%2C+ME%3BChorba%2C+T&rft.aulast=Favorov&rft.aufirst=M&rft.date=2010-12-01&rft.volume=14&rft.issue=12&rft.spage=1582&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Mortality; Data processing; Lung diseases; Territory; Tuberculosis; Mycobacterium ER - TY - JOUR T1 - Variation in School Health Policies and Programs by Demographic Characteristics of US Schools, 2006 AN - 839577590; 201100190 AB - BACKGROUND: To identify whether school health policies and programs vary by demographic characteristics of schools, using data from the School Health Policies and Programs Study (SHPPS) 2006. This study updates a similar study conducted with SHPPS 2000 data and assesses several additional policies and programs measured for the first time in SHPPS 2006. 8 components of the coordinated school health model using a nationally representative sample of public, Catholic, and private schools at the elementary, middle, and high school levels. Data were collected from school faculty and staff using computer-assisted personal interviews and then linked with extant data on school characteristics. RESULTS: Results from a series of regression analyses indicated that a number of school policies and programs varied by school type (public, Catholic, or private), urbanicity, school size, discretionary dollars per pupil, percentage of white students, percentage of students qualifying for free lunch funds, and, among high schools, percentage of college-bound students. Catholic and private schools, smaller schools, and those with low discretionary dollars per pupil did not have as many key school health policies and programs as did schools that were public, larger, and had higher discretionary dollars per pupil. However, no single type of school had all key components of a coordinated school health program in place. Although some categories of schools had fewer policies and programs in place, all had both strengths and weaknesses. Regardless of school characteristics, all schools have the potential to implement a quality school health program. Adapted from the source document. JF - Journal of School Health AU - Balaji, Alexandra B AU - Brener, Nancy D AU - McManus, Tim AD - Epidemiologist, Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Mailstop E-46, Atlanta, GA 30333 Y1 - 2010/12// PY - 2010 DA - December 2010 SP - 599 EP - 613 PB - Wiley-Blackwell, UK VL - 80 IS - 12 SN - 0022-4391, 0022-4391 KW - school health policies school health programs child and adolescent health demographic characteristics of schools KW - High schools KW - Private schools KW - Pupils KW - Roman Catholic schools KW - Health policy KW - Demographic aspects KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839577590?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+School+Health&rft.atitle=Variation+in+School+Health+Policies+and+Programs+by+Demographic+Characteristics+of+US+Schools%2C+2006&rft.au=Balaji%2C+Alexandra+B%3BBrener%2C+Nancy+D%3BMcManus%2C+Tim&rft.aulast=Balaji&rft.aufirst=Alexandra&rft.date=2010-12-01&rft.volume=80&rft.issue=12&rft.spage=599&rft.isbn=&rft.btitle=&rft.title=Journal+of+School+Health&rft.issn=00224391&rft_id=info:doi/10.1111%2Fj.1746-1561.2010.00547.x LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2011-01-10 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Roman Catholic schools; Health policy; Pupils; High schools; Demographic aspects; Private schools DO - http://dx.doi.org/10.1111/j.1746-1561.2010.00547.x ER - TY - JOUR T1 - Effectiveness of Policies Restricting Hours of Alcohol Sales in Preventing Excessive Alcohol Consumption and Related Harms AN - 839571715; 201101638 AB - Local, state, and national policies that limit the hours that alcoholic beverages may be available for sale might be a means of reducing excessive alcohol consumption and related harms. The methods of the Guide to Community Preventive Services were used to synthesize scientific evidence on the effectiveness of such policies. All of the studies included in this review assessed the effects of increasing hours of sale in on-premises settings (in which alcoholic beverages are consumed where purchased) in high-income nations. None of the studies was conducted in the U.S. The review team's initial assessment of this evidence suggested that changes of less than 2 hours were unlikely to significantly affect excessive alcohol consumption and related harms; to explore this hypothesis, studies assessing the effects of changing hours of sale by less than 2 hours and by 2 or more hours were assessed separately. There was sufficient evidence in ten qualifying studies to conclude that increasing hours of sale by 2 or more hours increases alcohol-related harms. Thus, disallowing extensions of hours of alcohol sales by 2 or more should be expected to prevent alcohol-related harms, while policies decreasing hours of sale by 2 hours or more at on-premises alcohol outlets may be an effective strategy for preventing alcohol-related harms. The evidence from six qualifying studies was insufficient to determine whether increasing hours of sale by less than 2 hours increases excessive alcohol consumption and related harms. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Hahn, Robert A AU - Kuzara, Jennifer L AU - Elder, Randy AU - Brewer, Robert AU - Chattopadhyay, Sajal AU - Fielding, Jonathan AU - Naimi, Timothy S AU - Toomey, Traci AU - Middleton, Jennifer Cook AU - Lawrence, Briana AD - Community Guide Branch, CDC, Atlanta, GA rhahn@cdc.gov Y1 - 2010/12// PY - 2010 DA - December 2010 SP - 590 EP - 604 PB - Elsevier Science, New York NY VL - 39 IS - 6 SN - 0749-3797, 0749-3797 KW - Assessment KW - Alcohol consumption KW - Sales KW - Alcoholic beverages KW - Alcohol related KW - Shops KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839571715?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Effectiveness+of+Policies+Restricting+Hours+of+Alcohol+Sales+in+Preventing+Excessive+Alcohol+Consumption+and+Related+Harms&rft.au=Hahn%2C+Robert+A%3BKuzara%2C+Jennifer+L%3BElder%2C+Randy%3BBrewer%2C+Robert%3BChattopadhyay%2C+Sajal%3BFielding%2C+Jonathan%3BNaimi%2C+Timothy+S%3BToomey%2C+Traci%3BMiddleton%2C+Jennifer+Cook%3BLawrence%2C+Briana&rft.aulast=Hahn&rft.aufirst=Robert&rft.date=2010-12-01&rft.volume=39&rft.issue=6&rft.spage=590&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2010.09.016 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2011-01-10 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Sales; Alcohol consumption; Alcoholic beverages; Alcohol related; Assessment; Shops DO - http://dx.doi.org/10.1016/j.amepre.2010.09.016 ER - TY - JOUR T1 - Mitochondrial dysfunction and loss of Parkinson's disease-linked proteins contribute to neurotoxicity of manganese-containing welding fumes. AN - 815962884; 20798247 AB - Welding generates complex metal aerosols, inhalation of which is linked to adverse health effects among welders. An important health concern of welding fume (WF) exposure is neurological dysfunction akin to Parkinson's disease (PD), thought to be mediated by manganese (Mn) in the fumes. Also, there is a proposition that welding might accelerate the onset of PD. Our recent findings link the presence of Mn in the WF with dopaminergic neurotoxicity seen in rats exposed to manual metal arc-hard surfacing (MMA-HS) or gas metal arc-mild steel (GMA-MS) fumes. To elucidate the molecular mechanisms further, we investigated the association of PD-linked (Park) genes and mitochondrial function in causing dopaminergic abnormality. Repeated instillations of the two fumes at doses that mimic ∼1 to 5 yr of worker exposure resulted in selective brain accumulation of Mn. This accumulation caused impairment of mitochondrial function and loss of tyrosine hydroxylase (TH) protein, indicative of dopaminergic injury. A fascinating finding was the altered expression of Parkin (Park2), Uchl1 (Park5), and Dj1 (Park7) proteins in dopaminergic brain areas. A similar regimen of manganese chloride (MnCl(2)) also caused extensive loss of striatal TH, mitochondrial electron transport components, and Park proteins. As mutations in PARK genes have been linked to early-onset PD in humans, and because welding is implicated as a risk factor for parkinsonism, PARK genes might play a critical role in WF-mediated dopaminergic dysfunction. Whether these molecular alterations culminate in neurobehavioral and neuropathological deficits reminiscent of PD remains to be ascertained. JF - FASEB journal : official publication of the Federation of American Societies for Experimental Biology AU - Sriram, Krishnan AU - Lin, Gary X AU - Jefferson, Amy M AU - Roberts, Jenny R AU - Wirth, Oliver AU - Hayashi, Yusuke AU - Krajnak, Kristine M AU - Soukup, Joleen M AU - Ghio, Andrew J AU - Reynolds, Steven H AU - Castranova, Vincent AU - Munson, Albert E AU - Antonini, James M AD - Toxicology and Molecular Biology Branch, Mailstop L-3014, CDC-NIOSH, 1095 Willowdale Rd., Morgantown, WV 26505, USA. kos4@cdc.gov Y1 - 2010/12// PY - 2010 DA - December 2010 SP - 4989 EP - 5002 VL - 24 IS - 12 KW - Air Pollutants, Occupational KW - 0 KW - Chlorides KW - Manganese Compounds KW - Manganese KW - 42Z2K6ZL8P KW - Tyrosine 3-Monooxygenase KW - EC 1.14.16.2 KW - Ubiquitin-Protein Ligases KW - EC 2.3.2.27 KW - parkin protein KW - UCHL1 protein, rat KW - EC 3.4.19.12 KW - Ubiquitin Thiolesterase KW - manganese chloride KW - QQE170PANO KW - Index Medicus KW - Chlorides -- toxicity KW - Animals KW - Tyrosine 3-Monooxygenase -- metabolism KW - Air Pollutants, Occupational -- toxicity KW - Rats KW - Polymerase Chain Reaction KW - Blotting, Western KW - Rats, Sprague-Dawley KW - Ubiquitin Thiolesterase -- metabolism KW - Ubiquitin Thiolesterase -- genetics KW - Tyrosine 3-Monooxygenase -- genetics KW - Ubiquitin-Protein Ligases -- genetics KW - Occupational Exposure -- adverse effects KW - Ubiquitin-Protein Ligases -- metabolism KW - Male KW - Inhalation Exposure -- adverse effects KW - Parkinson Disease -- etiology KW - Manganese -- metabolism KW - Parkinson Disease -- metabolism KW - Welding KW - Manganese -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/815962884?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=FASEB+journal+%3A+official+publication+of+the+Federation+of+American+Societies+for+Experimental+Biology&rft.atitle=Mitochondrial+dysfunction+and+loss+of+Parkinson%27s+disease-linked+proteins+contribute+to+neurotoxicity+of+manganese-containing+welding+fumes.&rft.au=Sriram%2C+Krishnan%3BLin%2C+Gary+X%3BJefferson%2C+Amy+M%3BRoberts%2C+Jenny+R%3BWirth%2C+Oliver%3BHayashi%2C+Yusuke%3BKrajnak%2C+Kristine+M%3BSoukup%2C+Joleen+M%3BGhio%2C+Andrew+J%3BReynolds%2C+Steven+H%3BCastranova%2C+Vincent%3BMunson%2C+Albert+E%3BAntonini%2C+James+M&rft.aulast=Sriram&rft.aufirst=Krishnan&rft.date=2010-12-01&rft.volume=24&rft.issue=12&rft.spage=4989&rft.isbn=&rft.btitle=&rft.title=FASEB+journal+%3A+official+publication+of+the+Federation+of+American+Societies+for+Experimental+Biology&rft.issn=1530-6860&rft_id=info:doi/10.1096%2Ffj.10-163964 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-01-04 N1 - Date created - 2010-12-02 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1096/fj.10-163964 ER - TY - JOUR T1 - Work-relatedness of selected chronic medical conditions and workers' compensation utilization: National health interview survey occupational health supplement data AN - 1017966736; 16691608 AB - Background An occupational health supplement (OHS) to the 1988 National Health Interview Survey (NHIS) bypassed many limitations of traditional occupational health surveillance systems, but the data collected about chronic work-related conditions have not yet been reported. Methods We calculated the prevalence and proportion of cases related to work for the aggregation of 13 chronic conditions included in the NHIS-OHS, and for 11 conditions individually. For each of nine conditions, and for the aggregation of all conditions, we also calculated the prevalence of workers' compensation claims filed. Results The overall prevalence of work-related chronic conditions was 7.5% (SE=0.16). The work-related conditions with the highest prevalence were repeated trouble with the back/neck/spine (4.91%; SE=0.13) and trouble hearing (1.14%; SE=0.06). Overall, workers' compensation claims were filed for 39.0% (SE=1.00) of work-related cases. Conclusions The burden of work-related illnesses in the US is substantial, and the workers' compensation system is underutilized. Am. J. Ind. Med. 53:1252-1263, 2010. ? 2010 Wiley-Liss, Inc. JF - American Journal of Industrial Medicine AU - Luckhaupt, Sara E AU - Calvert, Geoffrey M Y1 - 2010/12// PY - 2010 DA - Dec 2010 SP - 1252 EP - 1263 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 53 IS - 12 SN - 1097-0274, 1097-0274 KW - Toxicology Abstracts; Health & Safety Science Abstracts KW - workers' compensation KW - Workers KW - spine KW - Data processing KW - Spine KW - Hearing KW - Neck KW - Occupational health KW - H 1000:Occupational Safety and Health KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1017966736?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Work-relatedness+of+selected+chronic+medical+conditions+and+workers%27+compensation+utilization%3A+National+health+interview+survey+occupational+health+supplement+data&rft.au=Luckhaupt%2C+Sara+E%3BCalvert%2C+Geoffrey+M&rft.aulast=Luckhaupt&rft.aufirst=Sara&rft.date=2010-12-01&rft.volume=53&rft.issue=12&rft.spage=1252&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=10970274&rft_id=info:doi/10.1002%2Fajim.20885 L2 - http://onlinelibrary.wiley.com/doi/10.1002/ajim.20885/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2015-03-04 N1 - SubjectsTermNotLitGenreText - Workers; Spine; Data processing; Hearing; Neck; workers' compensation; spine; Occupational health DO - http://dx.doi.org/10.1002/ajim.20885 ER - TY - JOUR T1 - A two-stage, multilevel quality control system for serological assays in anthrax vaccine clinical trials AN - 954581847; 13890123 AB - A two-stage, multilevel assay quality control (QC) system was designed and implemented for two high stringency QC anthrax serological assays; a quantitative anti-PA IgG enzyme-linked immunosorbent assay (ELISA) and an anthrax lethal toxin neutralization activity (TNA) assay. The QC system and the assays were applied for the congressionally mandated Centers for Disease Control and Prevention (CDC) Phase 4 human clinical trial of anthrax vaccine adsorbed (AVA, BioThrax). A total of 57,284 human serum samples were evaluated by anti-PA enzyme-linked immunosorbent assay (ELISA) and 11,685 samples by anthrax lethal toxin neutralization activity (TNA) assay. The QC system demonstrated overall sample acceptance rates of 86% for ELISA and 90% for the TNA assays respectively. Monitoring of multiple assay and test sample variables showed no significant long term trends or degradation in any of the critical assay reagents or reportable values for both assays. Assay quality control data establish the functionality of the quality control system and demonstrates the reliability of the serological data generated using these assays. JF - Biologicals AU - Soroka, Stephen D AU - Schiffer, Jarad M AU - Semenova, Vera A AU - Li, Han AU - Foster, Lydia AU - Quinn, Conrad P AD - Microbial Pathogenesis and Immune Response (MPIR) Laboratory, Meningitis and Vaccine Preventable Diseases Branch, Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention (CDC), Atlanta, GA, United States, ssoroka@cdc.gov Y1 - 2010/11// PY - 2010 DA - Nov 2010 SP - 675 EP - 683 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 38 IS - 6 SN - 1045-1056, 1045-1056 KW - Toxicology Abstracts KW - Anthrax KW - Enzyme-linked immunosorbent assay KW - X:24370 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/954581847?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biologicals&rft.atitle=A+two-stage%2C+multilevel+quality+control+system+for+serological+assays+in+anthrax+vaccine+clinical+trials&rft.au=Soroka%2C+Stephen+D%3BSchiffer%2C+Jarad+M%3BSemenova%2C+Vera+A%3BLi%2C+Han%3BFoster%2C+Lydia%3BQuinn%2C+Conrad+P&rft.aulast=Soroka&rft.aufirst=Stephen&rft.date=2010-11-01&rft.volume=38&rft.issue=6&rft.spage=675&rft.isbn=&rft.btitle=&rft.title=Biologicals&rft.issn=10451056&rft_id=info:doi/10.1016%2Fj.biologicals.2010.09.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Enzyme-linked immunosorbent assay DO - http://dx.doi.org/10.1016/j.biologicals.2010.09.001 ER - TY - JOUR T1 - Knowledge, Attitudes, and Practices of US Travelers to Asia Regarding Seasonal Influenza and H5N1 Avian Influenza Prevention Measures AN - 904470201; 14097315 AB - Background. International travel is a potential risk factor for the spread of influenza. In the United States, approximately 5%-20% of the population develops an influenza-like illness annually. The purpose of this study was to describe the knowledge, attitude, and practices of US travelers to Asia regarding seasonal influenza and H5N1 avian influenza (AI) prevention measures. JF - Journal of Travel Medicine AU - Yanni, Emad A AU - Marano, Nina AU - Han, Pauline AU - Edelson, Paul J AU - Blumensaadt, Sena AU - Becker, Margaret AU - Dwyer, Susan AU - Crocker, Kim AU - Daley, Terrence AU - Davis, Xiaohong AU - Gallagher, Nancy AU - Balaban, Victor AU - McCarron, Margaret AU - Mounts, Anthony AU - Lipman, Harvey AU - Brown, Clive AU - Kozarsky, Phyllis AD - *Division of Global Migration and Quarantine, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA, Eyanni@cdc.gov Y1 - 2010/11// PY - 2010 DA - Nov 2010 SP - 374 EP - 381 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 USA VL - 17 IS - 6 SN - 1195-1982, 1195-1982 KW - Virology & AIDS Abstracts; Risk Abstracts KW - Fowl plague KW - Risk factors KW - Seasonal variations KW - Sulfur dioxide KW - Travel KW - attitudes KW - influenza KW - prevention KW - USA KW - Asia KW - V 22400:Human Diseases KW - R2 23010:General: Models, forecasting UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/904470201?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Travel+Medicine&rft.atitle=Knowledge%2C+Attitudes%2C+and+Practices+of+US+Travelers+to+Asia+Regarding+Seasonal+Influenza+and+H5N1+Avian+Influenza+Prevention+Measures&rft.au=Yanni%2C+Emad+A%3BMarano%2C+Nina%3BHan%2C+Pauline%3BEdelson%2C+Paul+J%3BBlumensaadt%2C+Sena%3BBecker%2C+Margaret%3BDwyer%2C+Susan%3BCrocker%2C+Kim%3BDaley%2C+Terrence%3BDavis%2C+Xiaohong%3BGallagher%2C+Nancy%3BBalaban%2C+Victor%3BMcCarron%2C+Margaret%3BMounts%2C+Anthony%3BLipman%2C+Harvey%3BBrown%2C+Clive%3BKozarsky%2C+Phyllis&rft.aulast=Yanni&rft.aufirst=Emad&rft.date=2010-11-01&rft.volume=17&rft.issue=6&rft.spage=374&rft.isbn=&rft.btitle=&rft.title=Journal+of+Travel+Medicine&rft.issn=11951982&rft_id=info:doi/10.1111%2Fj.1708-8305.2010.00458.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Number of references - 19 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - Travel; Fowl plague; Risk factors; Sulfur dioxide; prevention; Seasonal variations; attitudes; influenza; USA; Asia DO - http://dx.doi.org/10.1111/j.1708-8305.2010.00458.x ER - TY - JOUR T1 - Trends in low-risk lifestyle factors among adults in the United States: Findings from the Behavioral Risk Factor Surveillance System 1996-2007 AN - 899130672; 13954905 AB - Objective: Our objective was to examine recent trends in low-risk lifestyle factors for chronic diseases (not currently smoking, any exercise during the past 30 days, consuming fruits and vegetables >= 5 times per day, and body mass index = 18 years who participated in one of seven Behavioral Risk Factor Surveillance System surveys conducted from 1996 to 2007. Results: The age-adjusted percentage of adults meeting all four low-risk lifestyle factors was 8.5% in 1996 and 7.7% in 2007 (p for linear trend = 5 times per day, and who had a body mass index < 25 kg/m super(2) were 70.9%, 76.2%, 47.9% and 24.3%, respectively, in 1996 and 77.1%, 80.0%, 37.8%, and 24.5%, respectively, in 2007. Women and whites were more likely than their counterparts to meet all four criteria. Conclusions: From 1996 to 2007, the percentage of U.S. adults meeting all four low-risk lifestyle factors decreased slightly. JF - Preventive Medicine AU - Ford, Earl S AU - Li, Chaoyang AU - Zhao, Guixiang AU - Pearson, William S AU - Tsai, James AU - Greenlund, Kurt J AD - Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA, eford@cdc.gov Y1 - 2010/11// PY - 2010 DA - Nov 2010 SP - 403 EP - 407 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 51 IS - 5 SN - 0091-7435, 0091-7435 KW - Risk Abstracts KW - Ethnic groups KW - Smoking KW - USA KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/899130672?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Preventive+Medicine&rft.atitle=Trends+in+low-risk+lifestyle+factors+among+adults+in+the+United+States%3A+Findings+from+the+Behavioral+Risk+Factor+Surveillance+System+1996-2007&rft.au=Ford%2C+Earl+S%3BLi%2C+Chaoyang%3BZhao%2C+Guixiang%3BPearson%2C+William+S%3BTsai%2C+James%3BGreenlund%2C+Kurt+J&rft.aulast=Ford&rft.aufirst=Earl&rft.date=2010-11-01&rft.volume=51&rft.issue=5&rft.spage=403&rft.isbn=&rft.btitle=&rft.title=Preventive+Medicine&rft.issn=00917435&rft_id=info:doi/10.1016%2Fj.ypmed.2010.08.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Smoking; USA DO - http://dx.doi.org/10.1016/j.ypmed.2010.08.002 ER - TY - JOUR T1 - Maternal body mass index as a risk factor for craniosynostosis AN - 879476697; 15130408 JF - American Journal of Medical Genetics Part A AU - Boulet, Sheree L AU - Rasmussen, Sonja A AU - Honein, Margaret A AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, sboulet@cdc.gov Y1 - 2010/11/01/ PY - 2010 DA - 2010 Nov 01 SP - 2895 EP - 2897 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 USA VL - 152A IS - 11 SN - 1552-4833, 1552-4833 KW - Physical Education Index; Genetics Abstracts KW - Body mass KW - Genetics KW - Risk factors KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/879476697?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Medical+Genetics+Part+A&rft.atitle=Maternal+body+mass+index+as+a+risk+factor+for+craniosynostosis&rft.au=Boulet%2C+Sheree+L%3BRasmussen%2C+Sonja+A%3BHonein%2C+Margaret+A&rft.aulast=Boulet&rft.aufirst=Sheree&rft.date=2010-11-01&rft.volume=152A&rft.issue=11&rft.spage=2895&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Medical+Genetics+Part+A&rft.issn=15524833&rft_id=info:doi/10.1002%2Fajmg.a.33668 LA - English DB - Physical Education Index N1 - Date revised - 2011-07-01 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - Genetics; Risk factors; Body mass DO - http://dx.doi.org/10.1002/ajmg.a.33668 ER - TY - JOUR T1 - Mode of Action for Natural Products Isolated from Essential Oils of Two Trees is Different from Available Mosquito Adulticides AN - 851465105; 14037335 AB - Insecticidal properties of natural products may present alternatives to the use of synthetic molecule pesticides that are of diminishing effectiveness due to resistance. Three compounds, thymoquinone, nootkatone, and carvacrol, components of Alaska yellow cedar, Chamaecyyparis nootkatensis (D. Don) Spach, and incense cedar, Calocedrus decurrens (Torr.), essential oils, have been shown to have biological activity against a variety of mosquito and tick species. Although these components act as both repellents and insecticides, how they function in either capacity is unknown. Their use as mosquito control insecticides would be greatly increased if their mode of action is not the same as that of currently used commercial products. This study compared the lethal dosages for nootkatone, carvacrol, and thymoquinone by using colony strains of Anopheles gambiae Giles with known mutations at three different target sites. The altered target sites evaluated were the sodium channel para-locus mutation (L1014 F KDR) that confers permethrin resistance, the ACE-1 gene that confers organophosphate and carbamate resistance, and a gamma -aminobutyric acid receptor mutation of the Rdl locus conferring dieldrin resistance. Significant increases in lethal dose were not observed in any of the mosquito strains for any of the compounds tested compared with the doses required of chemicals with known modes of action at the mutated sites. Although the mode of action was not determined, this screening study indicates that none of these compounds interact at the target sites represented in the test mosquito strains. These compounds represent a different mode of action than existing chemicals currently used in mosquito control. JF - Journal of Medical Entomology AU - McAllister, Janet C AU - Adams, Mary F Y1 - 2010/11// PY - 2010 DA - Nov 2010 SP - 1123 EP - 1126 PB - Entomological Society of America, 9301 Annapolis Rd. Lanham MD 20706 USA VL - 47 IS - 6 SN - 0022-2585, 0022-2585 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Entomology Abstracts KW - mode of action KW - mosquitoes KW - nookatone KW - thymoquinone KW - carvacrol KW - incense KW - Trees KW - Pharmacology KW - natural products KW - Colonies KW - Insecticides KW - Aquatic drugs KW - Repellents KW - Calocedrus decurrens KW - Sodium channels KW - Aquatic insects KW - USA, Alaska KW - Carvacrol KW - Screening KW - Mutations KW - Ixodidae KW - Dieldrin KW - Permethrin KW - Pest control KW - organophosphates KW - Pesticides (carbamates) KW - Strains KW - Anopheles gambiae KW - gamma -Aminobutyric acid receptors KW - Pesticides KW - Essential oils KW - Mutation KW - Lethal dose KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - Q1 08485:Species interactions: pests and control KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/851465105?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Medical+Entomology&rft.atitle=Mode+of+Action+for+Natural+Products+Isolated+from+Essential+Oils+of+Two+Trees+is+Different+from+Available+Mosquito+Adulticides&rft.au=McAllister%2C+Janet+C%3BAdams%2C+Mary+F&rft.aulast=McAllister&rft.aufirst=Janet&rft.date=2010-11-01&rft.volume=47&rft.issue=6&rft.spage=1123&rft.isbn=&rft.btitle=&rft.title=Journal+of+Medical+Entomology&rft.issn=00222585&rft_id=info:doi/10.1603%2FME10098 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-02-01 N1 - Number of references - 14 N1 - Last updated - 2014-11-12 N1 - SubjectsTermNotLitGenreText - Screening; Insecticides; Pharmacology; Mutations; Aquatic drugs; Pesticides; Pest control; Strains; Aquatic insects; Carvacrol; incense; Trees; Dieldrin; Permethrin; natural products; organophosphates; Pesticides (carbamates); gamma -Aminobutyric acid receptors; Colonies; Repellents; Essential oils; Sodium channels; Mutation; Lethal dose; Ixodidae; Calocedrus decurrens; Anopheles gambiae; USA, Alaska DO - http://dx.doi.org/10.1603/ME10098 ER - TY - JOUR T1 - Evaluation of Methods to Determine Excessive Decline of Forced Expiratory Volume in One Second in Workers Exposed to Diacetyl-Containing Flavorings AN - 839709336; 14029606 AB - Objective: To evaluate methods for determining excessive short-term decline in forced expiratory volume in one second (FEV sub(1)) in diacetyl-exposed workers. Methods: We evaluated five methods of determining excessive longitudinal FEV sub(1) decline in diacetyl-exposed workers and workers from a comparative cohort: American Thoracic Society (ATS), ACOEM an 8% limit, and a relative and absolute longitudinal limit on the basis of spirometry data variability. Relative risk and incidence of excess decline were evaluated. Results: Incidence of excessive FEV sub(1) decline was 1% in the comparative cohort using ATS and ACOEM criteria, 4.1% using relative limit of longitudinal decline, 4.4% with absolute longitudinal limit of decline, and 5.6% by using the 8% limit. Relative risk of abnormal FEV sub(1) decline in diacetyl-exposed workers was elevated in all evaluated methods. Conclusion: Alternative methods for respiratory surveillance in diacetyl-exposed workers may be preferable to ATS or ACOEM. JF - Journal of Occupational and Environmental Medicine AU - Chaisson, N F AU - Kreiss, K AU - Hnizdo, E AU - Hakobyan, A AU - Enright, P L AD - 1095 Willowdale Rd, Mailstop-H2800, Morgantown, WV 26505, USA, kkreiss@cdc.gov Y1 - 2010/11// PY - 2010 DA - Nov 2010 SP - 1119 EP - 1123 VL - 52 IS - 11 SN - 1076-2752, 1076-2752 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Risk assessment KW - Food additives KW - Occupational safety KW - Respiratory system KW - R2 23080:Industrial and labor KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839709336?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Evaluation+of+Methods+to+Determine+Excessive+Decline+of+Forced+Expiratory+Volume+in+One+Second+in+Workers+Exposed+to+Diacetyl-Containing+Flavorings&rft.au=Chaisson%2C+N+F%3BKreiss%2C+K%3BHnizdo%2C+E%3BHakobyan%2C+A%3BEnright%2C+P+L&rft.aulast=Chaisson&rft.aufirst=N&rft.date=2010-11-01&rft.volume=52&rft.issue=11&rft.spage=1119&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e3181f84577 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Risk assessment; Food additives; Occupational safety; Respiratory system DO - http://dx.doi.org/10.1097/JOM.0b013e3181f84577 ER - TY - JOUR T1 - Well-Being Assessment: An Evaluation of Well-Being Scales for Public Health and Population Estimates of Well-Being among US Adults AN - 772252645; 201030292 AB - In 2008, the Centers for Disease Control and Prevention (CDC) supported testing of a number of well-being scales for potential use on public health surveillance systems. The purpose of this study was to examine the descriptive and psychometric properties of the scales (i.e. Satisfaction with Life, Meaning in Life, Positive and Negative Affect, Autonomy, Competence and Relatedness, and global and domain-specific life satisfaction) and to examine the distribution of well-being levels in a representative sample of community-dwelling US adults (N = 5,399) using a stratified analysis. The scales demonstrated acceptable psychometric properties. Responses were negatively skewed, with most respondents reporting mildly positive levels of subjective well-being. With the exception of autonomy, competence, and relatedness scales, all scales demonstrated good variability across socio-demographic subgroups. Older age and higher levels of education, and income, were associated with higher levels of subjective well-being. Most of the examined scales and related items merit consideration for continued testing in telephone surveys used in public health surveillance. Adapted from the source document. JF - Applied Psychology: Health and Well-Being AU - Kobau, Rosemarie AU - Sniezek, Joseph AU - Zack, Matthew M AU - Lucas, Richard E AU - Burns, Adam AD - National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA Y1 - 2010/11// PY - 2010 DA - November 2010 SP - 272 EP - 297 PB - Wiley-Blackwell, UK VL - 2 IS - 3 SN - 1758-0846, 1758-0846 KW - population health KW - psychometric analysis KW - US population surveys KW - well-being assessment KW - Competence KW - Wellbeing KW - Relatedness KW - Psychometric properties KW - Life satisfaction KW - Public health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/772252645?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+Psychology%3A+Health+and+Well-Being&rft.atitle=Well-Being+Assessment%3A+An+Evaluation+of+Well-Being+Scales+for+Public+Health+and+Population+Estimates+of+Well-Being+among+US+Adults&rft.au=Kobau%2C+Rosemarie%3BSniezek%2C+Joseph%3BZack%2C+Matthew+M%3BLucas%2C+Richard+E%3BBurns%2C+Adam&rft.aulast=Kobau&rft.aufirst=Rosemarie&rft.date=2010-11-01&rft.volume=2&rft.issue=3&rft.spage=272&rft.isbn=&rft.btitle=&rft.title=Applied+Psychology%3A+Health+and+Well-Being&rft.issn=17580846&rft_id=info:doi/ LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-11-11 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Wellbeing; Public health; Psychometric properties; Life satisfaction; Relatedness; Competence ER - TY - JOUR T1 - Glutamate carboxypeptidase II: an amyloid peptide-degrading enzyme with physiological function in the brain. AN - 762283791; 20624932 AB - Proteolytic processing of amyloid peptides (Aβs) is one important mechanism that controls the brain Aβ level. Although several Aβ-degrading enzymes were identified, evidence has suggested the presence of other peptidases. Here, we report a novel function of glutamate carboxypeptidase II (GCPII) in Aβ degradation in brain, which is a peptidase involved in N-acetylaspartylglutamate cleavage, folate metabolism, and prostate tumorigenesis. Maldi-Tof/MS analysis showed that recombinant human GCPII cleaved the Aβ1-40 and Aβ1-42 monomers at their C-termini, producing smaller fragments, and Aβ1-14 that lacked aggregation property and cellular toxicity. GCPII also degrades soluble oligomers and fibrils and can reduce the endogenous plaque size in brain sections obtained from amyloid precursor protein (APP) Swedish/presinilin (PS)-1ΔE9 transgenic mice. Overexpression of GCPII in either HEK293-APP Swedish cells or primary neurons and glial cells reduced the levels of secreted or exogenously supplemented Aβs and reduced Aβ-induced neurotoxicity, suggesting the biological significance of GCPII-mediated Aβ cleavage. Moreover, treatment of 8-mo-old transgenic mice for 1 mo with 2-(phosphonomethyl)-pentanedioic acid (10 mg/kg, intraperitoneally), a specific GCPII inhibitor, increased cerebral Aβ content. These results suggest an important physiological role for GCPII in Aβ clearance in brain and provide the evidence that dysregulation of GCPII is involved in Alzheimer's disease pathology. JF - FASEB journal : official publication of the Federation of American Societies for Experimental Biology AU - Kim, Min-Ju AU - Chae, San Sook AU - Koh, Young Ho AU - Lee, Suk Kyung AU - Jo, Sangmee Ahn AD - Division of Brain Diseases, Center for Biomedical Sciences, National Institute of Health, Korea Center for Disease Control and Prevention, Seoul, Korea. Y1 - 2010/11// PY - 2010 DA - November 2010 SP - 4491 EP - 4502 VL - 24 IS - 11 KW - 2-(phosphonomethyl)pentanedioic acid KW - 0 KW - Amyloidogenic Proteins KW - Enzyme Inhibitors KW - Organophosphorus Compounds KW - Glutamate Carboxypeptidase II KW - EC 3.4.17.21 KW - Index Medicus KW - Animals KW - Cells, Cultured KW - Humans KW - HEK293 Cells KW - Enzyme Activation -- drug effects KW - Organophosphorus Compounds -- pharmacology KW - Enzyme Inhibitors -- pharmacology KW - Mice KW - Up-Regulation KW - Mice, Transgenic KW - Alzheimer Disease -- enzymology KW - Brain -- enzymology KW - Brain -- drug effects KW - Amyloidogenic Proteins -- metabolism KW - Glutamate Carboxypeptidase II -- antagonists & inhibitors KW - Glutamate Carboxypeptidase II -- metabolism KW - Glutamate Carboxypeptidase II -- genetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/762283791?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=FASEB+journal+%3A+official+publication+of+the+Federation+of+American+Societies+for+Experimental+Biology&rft.atitle=Glutamate+carboxypeptidase+II%3A+an+amyloid+peptide-degrading+enzyme+with+physiological+function+in+the+brain.&rft.au=Kim%2C+Min-Ju%3BChae%2C+San+Sook%3BKoh%2C+Young+Ho%3BLee%2C+Suk+Kyung%3BJo%2C+Sangmee+Ahn&rft.aulast=Kim&rft.aufirst=Min-Ju&rft.date=2010-11-01&rft.volume=24&rft.issue=11&rft.spage=4491&rft.isbn=&rft.btitle=&rft.title=FASEB+journal+%3A+official+publication+of+the+Federation+of+American+Societies+for+Experimental+Biology&rft.issn=1530-6860&rft_id=info:doi/10.1096%2Ffj.09-148825 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-12-21 N1 - Date created - 2010-11-02 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1096/fj.09-148825 ER - TY - JOUR T1 - Challenges and strategies in applying performance measurement to federal public health programs AN - 754076774; 2010-584895 AB - Performance measurement is widely accepted in public health as an important management tool supporting program improvement and accountability. However, several challenges impede developing and implementing performance measurement systems at the federal level, including the complexity of public health problems that reflect multiple determinants and involve outcomes that may take years to achieve, the decentralized and networked nature of public health program implementation, and the lack of reliable and consistent data sources and other issues related to measurement. All three of these challenges hinder the ability to attribute program results to specific public health program efforts. The purpose of this paper is to explore these issues in detail and offer potential solutions that support the development of robust and practical performance measures to meet the needs for program improvement and accountability. Adapting performance measurement to public health programs is both an evolving science and art. Through the strategies presented here, appropriate systems can be developed and monitored to support the production of meaningful data that will inform effective decision making at multiple levels. [Copyright Elsevier Ltd.] JF - Evaluation and Program Planning AU - Degroff, Amy AU - Schooley, Michael AU - Chapel, Thomas AU - Poister, Theodore H AD - Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, United States Y1 - 2010/11// PY - 2010 DA - November 2010 SP - 365 EP - 372 PB - Elsevier Ltd., Amsterdam The Netherlands VL - 33 IS - 4 SN - 0149-7189, 0149-7189 KW - Health conditions and policy - Health and health policy KW - Business and service sector - Personnel management KW - Manufacturing and heavy industry - Industrial management, production, and productivity KW - Performance measurement Performance management Program evaluation KW - Measurement KW - Performance KW - Public health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754076774?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Evaluation+and+Program+Planning&rft.atitle=Challenges+and+strategies+in+applying+performance+measurement+to+federal+public+health+programs&rft.au=Degroff%2C+Amy%3BSchooley%2C+Michael%3BChapel%2C+Thomas%3BPoister%2C+Theodore+H&rft.aulast=Degroff&rft.aufirst=Amy&rft.date=2010-11-01&rft.volume=33&rft.issue=4&rft.spage=365&rft.isbn=&rft.btitle=&rft.title=Evaluation+and+Program+Planning&rft.issn=01497189&rft_id=info:doi/10.1016%2Fj.evalprogplan.2010.02.003 LA - English DB - PAIS Index N1 - Date revised - 2010-09-10 N1 - Last updated - 2016-09-28 N1 - CODEN - EPPLDO N1 - SubjectsTermNotLitGenreText - Public health; Performance; Measurement DO - http://dx.doi.org/10.1016/j.evalprogplan.2010.02.003 ER - TY - JOUR T1 - Projection of the year 2050 burden of diabetes in the US adult population: dynamic modeling of incidence, mortality, and prediabetes prevalence AN - 954601577; 14026511 AB - People with diabetes can suffer from diverse complications that seriously erode quality of life. Diabetes, costing the United States more than $174 billion per year in 2007, is expected to take an increasingly large financial toll in subsequent years. Accurate projections of diabetes burden are essential to policymakers planning for future health care needs and costs. Using data on prediabetes and diabetes prevalence in the United States, forecasted incidence, and current US Census projections of mortality and migration, the authors constructed a series of dynamic models employing systems of difference equations to project the future burden of diabetes among US adults. A three-state model partitions the US population into no diabetes, undiagnosed diabetes, and diagnosed diabetes. A four-state model divides the state of "no diabetes" into high-risk (prediabetes) and low-risk (normal glucose) states. A five-state model incorporates an intervention designed to prevent or delay diabetes in adults at high risk. The authors project that annual diagnosed diabetes incidence (new cases) will increase from about 8 cases per 1,000 in 2008 to about 15 in 2050. Assuming low incidence and relatively high diabetes mortality, total diabetes prevalence (diagnosed and undiagnosed cases) is projected to increase from 14% in 2010 to 21% of the US adult population by 2050. However, if recent increases in diabetes incidence continue and diabetes mortality is relatively low, prevalence will increase to 33% by 2050. A middle-ground scenario projects a prevalence of 25% to 28% by 2050. Intervention can reduce, but not eliminate, increases in diabetes prevalence. These projected increases are largely attributable to the aging of the US population, increasing numbers of members of higher-risk minority groups in the population, and people with diabetes living longer. Effective strategies will need to be undertaken to moderate the impact of these factors on national diabetes burden. Our analysis suggests that widespread implementation of reasonably effective preventive interventions focused on high-risk subgroups of the population can considerably reduce, but not eliminate, future increases in diabetes prevalence. JF - Population Health Metrics AU - Boyle, James P AU - Thompson, Theodore J AU - Gregg, Edward W AU - Barker, Lawrence E AU - Williamson, David F AD - Division of Diabetes Translation, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Mailstop K10, 4770 Buford Highway NE, Atlanta GA 30341 USA Y1 - 2010/10/22/ PY - 2010 DA - 2010 Oct 22 SP - 29 PB - BioMed Central Ltd., Middlesex House London W1T 4LB UK VL - 8 KW - Sustainability Science Abstracts KW - census KW - Mortality KW - Population dynamics KW - USA KW - diabetes mellitus KW - complications KW - Health care KW - intervention KW - quality of life KW - aging KW - M3 1010:Issues in Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/954601577?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Population+Health+Metrics&rft.atitle=Projection+of+the+year+2050+burden+of+diabetes+in+the+US+adult+population%3A+dynamic+modeling+of+incidence%2C+mortality%2C+and+prediabetes+prevalence&rft.au=Boyle%2C+James+P%3BThompson%2C+Theodore+J%3BGregg%2C+Edward+W%3BBarker%2C+Lawrence+E%3BWilliamson%2C+David+F&rft.aulast=Boyle&rft.aufirst=James&rft.date=2010-10-22&rft.volume=8&rft.issue=&rft.spage=29&rft.isbn=&rft.btitle=&rft.title=Population+Health+Metrics&rft.issn=1478-7954&rft_id=info:doi/10.1186%2F1478-7954-8-29 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2012-03-30 N1 - SubjectsTermNotLitGenreText - census; Mortality; diabetes mellitus; complications; Health care; intervention; quality of life; Population dynamics; aging; USA DO - http://dx.doi.org/10.1186/1478-7954-8-29 ER - TY - JOUR T1 - An aminopeptidase from Streptomyces sp. KK565 degrades beta amyloid monomers, oligomers and fibrils. AN - 756661796; 20828565 AB - The accumulation of beta amyloid (Aβ) has been a primary target for Alzheimer disease therapeutic strategies. Previously, we discovered an activity from Streptomyces sp. KK565 growth media that inhibits Aβ aggregation. The active component was an aminopeptidase and named Streptomyces sp. KK565 aminopeptidase (SKAP). SKAP cleaved N-terminal amino-acids of Aβ(1-42) monomer, inhibited formation of fibrils and protected Aβ(1-42)-induced neurotoxicity. Over-expression of a human homolog of SKAP, glutamate carboxypeptidase II (hGCPII) in Aβ-oversynthesizing cells dramatically reduced the Aβ levels. These findings suggest a possible role of M28 family peptidases in preventing Aβ deposits in mammalian brain. Copyright © 2010 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved. JF - FEBS letters AU - Yoo, Chulbae AU - Ahn, Kyungsook AU - Park, Jeong Eun AU - Kim, Min-Ju AU - Jo, Sangmee Ahn AD - Division of Brain Diseases, National Institute of Health, Korea Center for Disease Control and Prevention, Seoul, Republic of Korea. Y1 - 2010/10/08/ PY - 2010 DA - 2010 Oct 08 SP - 4157 EP - 4162 VL - 584 IS - 19 KW - Amyloid beta-Peptides KW - 0 KW - Antigens, Surface KW - Bacterial Proteins KW - Neuroprotective Agents KW - Peptide Fragments KW - Recombinant Proteins KW - amyloid beta-protein (1-40) KW - amyloid beta-protein (1-42) KW - Aminopeptidases KW - EC 3.4.11.- KW - Glutamate Carboxypeptidase II KW - EC 3.4.17.21 KW - glutamate carboxypeptidase II, human KW - Index Medicus KW - Peptide Fragments -- metabolism KW - Peptide Fragments -- toxicity KW - Genes, Bacterial KW - Neurons -- drug effects KW - Humans KW - Amino Acid Sequence KW - Glutamate Carboxypeptidase II -- metabolism KW - Recombinant Proteins -- genetics KW - Antigens, Surface -- genetics KW - Glutamate Carboxypeptidase II -- genetics KW - Cloning, Molecular KW - Recombinant Proteins -- toxicity KW - Peptide Fragments -- chemistry KW - Cell Survival -- drug effects KW - Recombinant Proteins -- metabolism KW - Neurons -- cytology KW - In Vitro Techniques KW - Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization KW - Neuroprotective Agents -- metabolism KW - Molecular Sequence Data KW - Substrate Specificity KW - Antigens, Surface -- metabolism KW - Sequence Homology, Amino Acid KW - Cell Line KW - Streptomyces -- enzymology KW - Aminopeptidases -- genetics KW - Bacterial Proteins -- genetics KW - Amyloid beta-Peptides -- metabolism KW - Streptomyces -- genetics KW - Amyloid beta-Peptides -- toxicity KW - Bacterial Proteins -- metabolism KW - Amyloid beta-Peptides -- chemistry KW - Aminopeptidases -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/756661796?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=FEBS+letters&rft.atitle=An+aminopeptidase+from+Streptomyces+sp.+KK565+degrades+beta+amyloid+monomers%2C+oligomers+and+fibrils.&rft.au=Yoo%2C+Chulbae%3BAhn%2C+Kyungsook%3BPark%2C+Jeong+Eun%3BKim%2C+Min-Ju%3BJo%2C+Sangmee+Ahn&rft.aulast=Yoo&rft.aufirst=Chulbae&rft.date=2010-10-08&rft.volume=584&rft.issue=19&rft.spage=4157&rft.isbn=&rft.btitle=&rft.title=FEBS+letters&rft.issn=1873-3468&rft_id=info:doi/10.1016%2Fj.febslet.2010.08.048 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-10-29 N1 - Date created - 2010-10-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.febslet.2010.08.048 ER - TY - JOUR T1 - Factors Affecting the Willingness of Counselors to Integrate Preconception Care into Sexually Transmitted Disease Clinics AN - 954591544; 13945757 AB - The high rate of unintended pregnancy is an immediate barrier to providing preconception care (PCC). Failure to deliver additional PCC messages at sexually transmitted disease (STD) clinics might represent a major missed opportunity to target women at increased risk for unintended pregnancy for behaviors that also put them at risk for adverse pregnancy outcomes. Methods: Using a survey questionnaire, we assessed perceptions of PCC and factors influencing the willingness of STD counselors to integrate PCC as an intervention service provided by the STD clinics of 140 STD counselors. We used a cross-sectional design and selected survey participants with a minimum of 2 years' experience in providing HIV pretest and posttest counseling and syphilis interviewing using a nonprobability, purposive sample. Results: The level of occupational responsibility and the amount of time available seemed to affect counselor perceptions of the importance of PCC and whether it should be integrated as an intervention service provided by STD clinics. Findings suggested that, although most STD counselors reported that PCC was an important issue, there was significant variation in the perception of whether PCC should be delivered at STD clinics. Conclusion: STD counselors perceived PCC to be an important intervention service that can be delivered at STD clinics. Additional study is needed to identify factors that might affect full integration into the STD clinic setting. JF - Women's Health Issues AU - Parker, Christopher S AU - Ghaddar, Sana AU - Zhang, Qing AU - Cooke, Brandi AD - National Center on Birth Defects and Developmental Disabilities (NCB III), Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, cparker@cdc.gov Y1 - 2010/10// PY - 2010 DA - Oct 2010 SP - 329 EP - 334 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 20 IS - 5 SN - 1049-3867, 1049-3867 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Perception KW - Human immunodeficiency virus KW - intervention KW - Treponema pallidum KW - sexually transmitted diseases KW - syphilis KW - Pregnancy KW - responsibility KW - H 1000:Occupational Safety and Health KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/954591544?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Women%27s+Health+Issues&rft.atitle=Factors+Affecting+the+Willingness+of+Counselors+to+Integrate+Preconception+Care+into+Sexually+Transmitted+Disease+Clinics&rft.au=Parker%2C+Christopher+S%3BGhaddar%2C+Sana%3BZhang%2C+Qing%3BCooke%2C+Brandi&rft.aulast=Parker&rft.aufirst=Christopher&rft.date=2010-10-01&rft.volume=20&rft.issue=5&rft.spage=329&rft.isbn=&rft.btitle=&rft.title=Women%27s+Health+Issues&rft.issn=10493867&rft_id=info:doi/10.1016%2Fj.whi.2010.05.005 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - Human immunodeficiency virus; Perception; intervention; syphilis; sexually transmitted diseases; responsibility; Pregnancy; Treponema pallidum DO - http://dx.doi.org/10.1016/j.whi.2010.05.005 ER - TY - JOUR T1 - The Impact of the Availability of School Vending Machines on Eating Behavior during Lunch: The Youth Physical Activity and Nutrition Survey AN - 954582544; 13955259 AB - Childhood obesity is a major public health concern and is associated with substantial morbidities. Access to less-healthy foods might facilitate dietary behaviors that contribute to obesity. However, less-healthy foods are usually available in school vending machines. This cross-sectional study examined the prevalence of students buying snacks or beverages from school vending machines instead of buying school lunch and predictors of this behavior. Analyses were based on the 2003 Florida Youth Physical Activity and Nutrition Survey using a representative sample of 4,322 students in grades six through eight in 73 Florida public middle schools. Analyses included [chi] super(2) tests and logistic regression. The outcome measure was buying a snack or beverage from vending machines 2 or more days during the previous 5 days instead of buying lunch. The survey response rate was 72%. Eighteen percent of respondents reported purchasing a snack or beverage from a vending machine 2 or more days during the previous 5 school days instead of buying school lunch. Although healthier options were available, the most commonly purchased vending machine items were chips, pretzels/crackers, candy bars, soda, and sport drinks. More students chose snacks or beverages instead of lunch in schools where beverage vending machines were also available than did students in schools where beverage vending machines were unavailable: 19% and 7%, respectively (P<=0.05). The strongest risk factor for buying snacks or beverages from vending machines instead of buying school lunch was availability of beverage vending machines in schools (adjusted odds ratio=3.5; 95% confidence interval, 2.2 to 5.7). Other statistically significant risk factors were smoking, non-Hispanic black race/ethnicity, Hispanic ethnicity, and older age. Although healthier choices were available, the most common choices were the less-healthy foods. Schools should consider developing policies to reduce the availability of less-healthy choices in vending machines and to reduce access to beverage vending machines. JF - Journal of the American Dietetic Association AU - Park, Sohyun AU - Sappenfield, William M AU - Huang, Youjie AU - Sherry, Bettylou AU - Bensyl, Diana M Y1 - 2010/10// PY - 2010 DA - Oct 2010 SP - 1532 EP - 1536 PB - Elsevier Science, Box 882 New York NY 10159 USA VL - 110 IS - 10 SN - 0002-8223, 0002-8223 KW - Physical Education Index; Health & Safety Science Abstracts KW - Analysis KW - Schools KW - USA, Florida KW - schools KW - PE:030 KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/954582544?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+American+Dietetic+Association&rft.atitle=The+Impact+of+the+Availability+of+School+Vending+Machines+on+Eating+Behavior+during+Lunch%3A+The+Youth+Physical+Activity+and+Nutrition+Survey&rft.au=Park%2C+Sohyun%3BSappenfield%2C+William+M%3BHuang%2C+Youjie%3BSherry%2C+Bettylou%3BBensyl%2C+Diana+M&rft.aulast=Park&rft.aufirst=Sohyun&rft.date=2010-10-01&rft.volume=110&rft.issue=10&rft.spage=1532&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+American+Dietetic+Association&rft.issn=00028223&rft_id=info:doi/10.1016%2Fj.jada.2010.07.003 LA - English DB - Physical Education Index; ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Schools; schools; USA, Florida DO - http://dx.doi.org/10.1016/j.jada.2010.07.003 ER - TY - JOUR T1 - Reduced risk of transfusion-transmitted HIV in Kenya through centrally co-ordinated blood centres, stringent donor selection and effective p24 antigen-HIV antibody screening AN - 954574994; 13825298 AB - Background Following a 1994 study showing a high rate of transfusion-associated HIV, Kenya implemented WHO blood safety recommendations including: organizing the Kenya National Blood Transfusion Service (NBTS), stringent blood donor selection, and universal screening with fourth-generation p24 antigen and HIV antibody assays. Here, we estimate the risk of transfusion-associated HIV transmission in Kenya resulting from NBTS laboratory error and consider the potential safety benefit of instituting pooled nucleic acid testing (NAT) to reduce window period transmission.Methods From November to December 2008 in one NBTS regional centre, and from March to June 2009 in all six NBTS regional centres, every third unit of blood screened negative for HIV by the national algorithm was selected. Dried blood spots were prepared and sent to a reference laboratory for further testing, including NAT. Test results from the reference laboratory and NBTS were compared. Risk of transfusion-associated HIV transmission owing to laboratory error and the estimated yield of implementing NAT were calculated.Findings No cases of laboratory error were detected in 12 435 units tested. We estimate that during the study period, the percentage of units reactive for HIV by NAT but non-reactive by the national algorithm was 0.0% (95% exact binomial confidence interval, 0.00-0.024%).Interpretation By adopting WHO blood safety strategies for resource-limited settings, Kenya has substantially reduced the risk of transfusion-associated HIV infection. As the national testing and donor selection algorithm is effective, implementing NAT is unlikely to add a significant safety benefit. These findings should encourage other countries in the region to fully adopt the WHO strategies. JF - Vox Sanguinis AU - Basavaraju, S V AU - Mwangi, J AU - Nyamongo, J AU - Zeh, C AU - Kimani, D AU - Shiraishi, R W AU - Madoda, R AU - Okonji, JA AU - Sugut, W AU - Ongwae, S AU - Pitman, J P AU - Marum, L H AD - 1HIV Prevention Branch, Global AIDS Program, National Center for HIV-AIDS, viral Hepatitis, STD and TB Prevention, U.S. Centers for Disease Control and Prevention, Atlanta, GA, USA, etu7@cdc.gov Y1 - 2010/10// PY - 2010 DA - Oct 2010 SP - 212 EP - 219 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 USA VL - 99 IS - 3 SN - 0042-9007, 0042-9007 KW - Risk Abstracts KW - risk reduction KW - Kenya KW - disease transmission KW - Human immunodeficiency virus KW - blood donors KW - infection KW - transfusion KW - Nucleic acids KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/954574994?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vox+Sanguinis&rft.atitle=Reduced+risk+of+transfusion-transmitted+HIV+in+Kenya+through+centrally+co-ordinated+blood+centres%2C+stringent+donor+selection+and+effective+p24+antigen-HIV+antibody+screening&rft.au=Basavaraju%2C+S+V%3BMwangi%2C+J%3BNyamongo%2C+J%3BZeh%2C+C%3BKimani%2C+D%3BShiraishi%2C+R+W%3BMadoda%2C+R%3BOkonji%2C+JA%3BSugut%2C+W%3BOngwae%2C+S%3BPitman%2C+J+P%3BMarum%2C+L+H&rft.aulast=Basavaraju&rft.aufirst=S&rft.date=2010-10-01&rft.volume=99&rft.issue=3&rft.spage=212&rft.isbn=&rft.btitle=&rft.title=Vox+Sanguinis&rft.issn=00429007&rft_id=info:doi/10.1111%2Fj.1423-0410.2010.01340.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Number of references - 26 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - risk reduction; disease transmission; Human immunodeficiency virus; blood donors; infection; transfusion; Nucleic acids; Kenya DO - http://dx.doi.org/10.1111/j.1423-0410.2010.01340.x ER - TY - JOUR T1 - Multiple healthy behaviors and optimal self-rated health: Findings from the 2007 Behavioral Risk Factor Surveillance System Survey AN - 899140523; 13941117 AB - Objective: The aim of this study was to examine the association between the number of healthy behaviors (i.e., not currently smoking, not currently drinking excessively, physically active, and consuming fruits and vegetables five or more times per day) and optimal self-rated health (SRH) among U.S. adults or adults with cardiovascular diseases (CVDs) or diabetes. Methods: We estimated the age-standardized prevalence of optimal SRH among a total of 430,912 adults who participated in the 2007 Behavioral Risk Factor Surveillance System (BRFSS). Prevalence ratios were produced with multivariate Cox regression models using number of healthy behaviors as a predictor; status of optimal SRH was used as an outcome variable while controlling for sociodemographic and health risk factors. Results: The age-standardized prevalence of reporting optimal SRH was 83.5%, 55.6%, and 56.3% among adults overall, and adults with CVDs or diabetes, respectively. Also in the aforementioned order, adults who reported having four healthy behaviors had 33%, 85%, and 87% increased likelihoods of reporting optimal SRH, when compared to their counterparts who reported none of these behaviors. Conclusion: The findings of this study indicate that number of healthy behaviors is associated with optimal SRH among adults, especially adults with CVDs or diabetes. These findings reinforce the support for identifying and implementing clinical and population-based intervention strategies that effectively promote multiple healthier lifestyle behaviors among adults. JF - Preventive Medicine AU - Tsai, James AU - Ford, Earl S AU - Li, Chaoyang AU - Zhao, Guixiang AU - Pearson, William S AU - Balluz, Lina S AD - Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion Centers for Disease Control and Prevention, Atlanta, GA 30341, USA, jxt9@cdc.gov Y1 - 2010/10// PY - 2010 DA - Oct 2010 SP - 268 EP - 274 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 51 IS - 3-4 SN - 0091-7435, 0091-7435 KW - Risk Abstracts KW - Behavior KW - USA KW - diabetes mellitus KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/899140523?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Preventive+Medicine&rft.atitle=Multiple+healthy+behaviors+and+optimal+self-rated+health%3A+Findings+from+the+2007+Behavioral+Risk+Factor+Surveillance+System+Survey&rft.au=Tsai%2C+James%3BFord%2C+Earl+S%3BLi%2C+Chaoyang%3BZhao%2C+Guixiang%3BPearson%2C+William+S%3BBalluz%2C+Lina+S&rft.aulast=Tsai&rft.aufirst=James&rft.date=2010-10-01&rft.volume=51&rft.issue=3-4&rft.spage=268&rft.isbn=&rft.btitle=&rft.title=Preventive+Medicine&rft.issn=00917435&rft_id=info:doi/10.1016%2Fj.ypmed.2010.07.010 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - diabetes mellitus; USA DO - http://dx.doi.org/10.1016/j.ypmed.2010.07.010 ER - TY - JOUR T1 - Evaluation of Fire-Safety Programs that use 10-Year Smoke Alarms AN - 899137936; 15510381 AB - The Centers for Disease Control and Prevention began funding a Smoke Alarm Installation and Fire Safety Education (SAIFE) program in 1998. This program involves the installation of lithium-powered "10-year" smoke alarms in homes at high risk for fires and injuries. This study aimed to (1) determine among original SAIFE homes if the lithium-powered alarms were still present and functional 8-10 years after installation and (2) understand factors related to smoke alarm presence and functionality. Data on a total of 384 homes and 601 smoke alarms in five states were collected and analyzed. Only one-third of alarms were still functional; 37% of installed alarms were missing; and 30% of alarms were present, but not functioning. Alarms were less likely to be functioning if they were installed in the kitchen and if homes had a different resident at follow-up. Of the 351 alarms that were present and had a battery at the time of the evaluation, only 21% contained lithium-powered batteries. Of these, 78% were still functioning. Programs that install lithium-powered alarms should use units that have sealed-in batteries and "hush" buttons. Additionally, education should be given on smoke alarm maintenance that includes a message that batteries in these alarms should not be replaced. Lithium-powered smoke alarms should last up to 10 years if maintained properly. JF - Journal of Community Health AU - Jackson, Mark AU - Wilson, Jonathan AU - Akoto, Judith AU - Dixon, Sherry AU - Jacobs, David E AU - Ballesteros, Michael F AD - Division of Unintentional Injury Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Mailstop F-62, Atlanta, GA, 30341, USA Y1 - 2010/10// PY - 2010 DA - Oct 2010 SP - 543 EP - 548 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 35 IS - 5 SN - 0094-5145, 0094-5145 KW - Risk Abstracts KW - Fires KW - Injuries KW - disease control KW - Maintenance KW - Education KW - Batteries KW - Alarm systems KW - prevention KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/899137936?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Community+Health&rft.atitle=Evaluation+of+Fire-Safety+Programs+that+use+10-Year+Smoke+Alarms&rft.au=Jackson%2C+Mark%3BWilson%2C+Jonathan%3BAkoto%2C+Judith%3BDixon%2C+Sherry%3BJacobs%2C+David+E%3BBallesteros%2C+Michael+F&rft.aulast=Jackson&rft.aufirst=Mark&rft.date=2010-10-01&rft.volume=35&rft.issue=5&rft.spage=543&rft.isbn=&rft.btitle=&rft.title=Journal+of+Community+Health&rft.issn=00945145&rft_id=info:doi/10.1007%2Fs10900-010-9240-y LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Fires; Education; Injuries; Batteries; Alarm systems; prevention; disease control; Maintenance DO - http://dx.doi.org/10.1007/s10900-010-9240-y ER - TY - JOUR T1 - Quantification of print, radio and television exposure among previous blood donors in Kenya: an opportunity for encouraging repeat donation in a resource-limited setting? AN - 899130720; 13825287 AB - Blood services in sub-Saharan Africa experience blood shortages and low retention of voluntary, non-remunerated donors. To boost collections by encouraging repeat donations, the Kenya National Blood Transfusion Service is exploring the likelihood of reaching previous donors through targeted print, radio and television advertising. We analysed data from a national AIDS Indicator Survey to determine whether previous donors have significant exposure to media. Respondents reporting history of blood donation had significantly higher exposure to print, radio and television media than those without history of blood donation. Targeted media campaigns encouraging repeat donation are likely to reach previous donors even in resource-limited settings. JF - Vox Sanguinis AU - Basavaraju, S V AU - Mwangi, J AU - Kellogg, T A AU - Odawo, L AU - Marum, L H AD - 1HIV Prevention Branch, Global AIDS Program, National Center for HIV-AIDS, Viral Hepatitis, STD and TB Prevention, U.S. Centers for Disease Control and Prevention, Atlanta, GA, USA, etu7@cdc.gov Y1 - 2010/10// PY - 2010 DA - Oct 2010 SP - 274 EP - 277 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 USA VL - 99 IS - 3 SN - 0042-9007, 0042-9007 KW - Toxicology Abstracts KW - Acquired immune deficiency syndrome KW - Blood donors KW - Blood transfusion KW - Data processing KW - X 24490:Other UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/899130720?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vox+Sanguinis&rft.atitle=Quantification+of+print%2C+radio+and+television+exposure+among+previous+blood+donors+in+Kenya%3A+an+opportunity+for+encouraging+repeat+donation+in+a+resource-limited+setting%3F&rft.au=Basavaraju%2C+S+V%3BMwangi%2C+J%3BKellogg%2C+T+A%3BOdawo%2C+L%3BMarum%2C+L+H&rft.aulast=Basavaraju&rft.aufirst=S&rft.date=2010-10-01&rft.volume=99&rft.issue=3&rft.spage=274&rft.isbn=&rft.btitle=&rft.title=Vox+Sanguinis&rft.issn=00429007&rft_id=info:doi/10.1111%2Fj.1423-0410.2010.01369.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Number of references - 9 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - Blood donors; Acquired immune deficiency syndrome; Blood transfusion; Data processing DO - http://dx.doi.org/10.1111/j.1423-0410.2010.01369.x ER - TY - JOUR T1 - Maternal Nativity Status and Birth Outcomes in Asian Immigrants AN - 877591498; 13706387 AB - Background The study examines the relationship between maternal nativity, maternal risks and birth outcomes in six Asian sub-populations. Methods U.S.- versus foreign-born immigrants of Chinese (67,222), Japanese (18,275) and Filipino (87,1208), Vietnamese (45,229), Cambodian/Laotian (21,237), and Korean (23,430) singleton live births were assessed for maternal risks and birth outcomes. Results U.S.-born Chinese and Japanese mothers had lower risk and increased preterm births but similar infant mortality, while U.S.-born Filipino mothers had higher risk and higher infant mortality. U.S.-born mothers of more recent Cambodian/Laotian and Vietnamese immigrants had higher risk and delivered more small and preterm births, while U.S.-born Korean mothers had higher risk but no differences in preterm and low birthweight delivery. Discussion Asians in America are a distinctly heterogenous population in terms of the relationship between maternal risk factors and birth outcomes and the influence of maternal nativity on this relationship. JF - Journal of Immigrant and Minority Health AU - Qin, Cheng AU - Gould, Jeffrey B AD - University of California, Berkeley, CA, USA, caq9@cdc.gov Y1 - 2010/10// PY - 2010 DA - Oct 2010 SP - 798 EP - 805 PB - Springer New York, LLC, 233 Spring St New York NY 10013-1578 USA VL - 12 IS - 5 SN - 1557-1912, 1557-1912 KW - Risk Abstracts KW - infant mortality KW - immigrants KW - low-birth-weight KW - Japan KW - Ethnic groups KW - Pregnancy KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/877591498?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Immigrant+and+Minority+Health&rft.atitle=Maternal+Nativity+Status+and+Birth+Outcomes+in+Asian+Immigrants&rft.au=Qin%2C+Cheng%3BGould%2C+Jeffrey+B&rft.aulast=Qin&rft.aufirst=Cheng&rft.date=2010-10-01&rft.volume=12&rft.issue=5&rft.spage=798&rft.isbn=&rft.btitle=&rft.title=Journal+of+Immigrant+and+Minority+Health&rft.issn=15571912&rft_id=info:doi/10.1007%2Fs10903-008-9215-6 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-10-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - infant mortality; immigrants; low-birth-weight; Ethnic groups; Pregnancy; Japan DO - http://dx.doi.org/10.1007/s10903-008-9215-6 ER - TY - JOUR T1 - What is the single most important thing you can do to prevent injuries in a crash? AN - 867750195; 13998128 JF - Journal of Safety Research AU - Roehler, Douglas R AU - Dellinger, Ann M AD - University of Michigan School of Public Heath, Ann Arbor, Michigan, USA, amd1@cdc.gov Y1 - 2010/10// PY - 2010 DA - Oct 2010 SP - 459 EP - 462 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK VL - 41 IS - 5 SN - 0022-4375, 0022-4375 KW - Health & Safety Science Abstracts KW - Injuries KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/867750195?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Safety+Research&rft.atitle=What+is+the+single+most+important+thing+you+can+do+to+prevent+injuries+in+a+crash%3F&rft.au=Roehler%2C+Douglas+R%3BDellinger%2C+Ann+M&rft.aulast=Roehler&rft.aufirst=Douglas&rft.date=2010-10-01&rft.volume=41&rft.issue=5&rft.spage=459&rft.isbn=&rft.btitle=&rft.title=Journal+of+Safety+Research&rft.issn=00224375&rft_id=info:doi/10.1016%2Fj.jsr.2010.08.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-05-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Injuries DO - http://dx.doi.org/10.1016/j.jsr.2010.08.001 ER - TY - JOUR T1 - Employment impact and financial burden for families of children with fragile X syndrome: findings from the National Fragile X Survey AN - 839575936; 201103213 AB - Background The employment impact and financial burden experienced by families of children with fragile X syndrome (FXS) has not been quantified in the USA. Method fragile X family survey, we analysed data on 1019 families with at least one child who had a full FXS mutation. Out-of-pocket expenditures related to fragile X were reported. We used logistic regression to examine the role of insurance, number of affected children, and number of total co-occurring conditions in predicting the financial burden and employment impact of FXS, while adjusting for race, education, marital status and other sociodemographic predictors. Results Almost half of families affected by FXS reported that they had experienced an increased financial burden and nearly 60% stated that they had had to change work hours or stop work because of FXS. Families with health insurance that met family needs were significantly less likely to report an excess financial burden. The type of insurance (private or public) was not associated with the reported financial burden. Affected children's mutation status, especially male children with the full mutation, was associated with employment impact. The total number of co-occurring conditions was associated with both financial burden and employment impact. Conclusions experienced a significant employment impact and financial burden. Policies designed to help families with FXS need to take into consideration the dimension of co-occurring conditions. Adapted from the source document. JF - Journal of Intellectual Disability Research AU - Ouyang, L AU - Grosse, S AU - Raspa, M AU - Bailey, D AD - Division of Human Development and Disability, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA Y1 - 2010/10// PY - 2010 DA - October 2010 SP - 918 EP - 928 PB - Blackwell Publishing, Oxford UK VL - 54 IS - 10 SN - 0964-2633, 0964-2633 KW - co-occurring conditions employment financial burden fragile X syndrome full mutation health insurance KW - Fragile X syndrome KW - Health insurance KW - Employment KW - Employment status KW - Children KW - Burden KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839575936?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Intellectual+Disability+Research&rft.atitle=Employment+impact+and+financial+burden+for+families+of+children+with+fragile+X+syndrome%3A+findings+from+the+National+Fragile+X+Survey&rft.au=Ouyang%2C+L%3BGrosse%2C+S%3BRaspa%2C+M%3BBailey%2C+D&rft.aulast=Ouyang&rft.aufirst=L&rft.date=2010-10-01&rft.volume=54&rft.issue=10&rft.spage=918&rft.isbn=&rft.btitle=&rft.title=Journal+of+Intellectual+Disability+Research&rft.issn=09642633&rft_id=info:doi/10.1111%2Fj.1365-2788.2010.01320.x LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2011-01-10 N1 - Last updated - 2016-09-27 N1 - CODEN - JIDREN N1 - SubjectsTermNotLitGenreText - Fragile X syndrome; Burden; Children; Employment; Health insurance; Employment status DO - http://dx.doi.org/10.1111/j.1365-2788.2010.01320.x ER - TY - JOUR T1 - Trend and Prevalence Estimates Based on the 2008 Physical Activity Guidelines for Americans AN - 822514739; 2010-644561 AB - According to the 2008 Physical Activity Guidelines for Americans, adults need to engage in at least 150 minutes/week of moderate-intensity activity or its equivalent (defined as aerobically active) to obtain substantial health benefits and more than 300 minutes/week (defined as highly active) to obtain more extensive health benefits. In addition to aerobic activity, the 2008 Guidelines recommend that adults participate in muscle-strengthening activities on 2 or more days/week. Objective: This study examined the prevalence and trends of meeting the activity criteria defined by the 2008 Guidelines among U.S. adults. Methods: Prevalence and trends of participation in leisure-time physical activity were estimated from the 1998-2008 National Health Interview Survey (analyzed in 2010). Results: In 2008, 43.5% of U.S. adults were aerobically active, 28.4% were highly active, 21.9% met the muscle-strengthening guideline, and 18.2% both met the muscle-strengthening guideline and were aerobically active. The likelihood of meeting each of these four activity criteria was similar and were associated with being male, being younger, being non-Hispanic white, having higher levels of education, and having a lowerI. Trends over time were also similar for each part of the 2008 Guidelines, with the prevalence of participation exhibiting a small but significant increase when comparing 1998 to 2008 (difference ranging from 2.4 to 4.2 percentage points). Conclusions: Little progress has been made during the past 10 years in increasing physical activity levels in the U.S. There is much room for improvement in achieving recommended levels of physical activity among Americans, particularly among relatively inactive subgroups. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Carlson, Susan A AU - Fulton, Janet E AU - Schoenborn, Charlotte A AU - Loustalot, Fleetwood AD - National Center for Chronic Disease Prevention and Health Promotion, CDC, Atlanta, Georgia Y1 - 2010/10// PY - 2010 DA - October 2010 SP - 305 EP - 313 PB - Elsevier Science, New York NY VL - 39 IS - 4 SN - 0749-3797, 0749-3797 KW - Health conditions and policy - Health and health policy KW - Population groups, population policy, and demographics - Demography and census KW - Social conditions and policy - Social research KW - United States KW - Physical fitness KW - Health surveys KW - Adults KW - Public health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/822514739?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Trend+and+Prevalence+Estimates+Based+on+the+2008+Physical+Activity+Guidelines+for+Americans&rft.au=Carlson%2C+Susan+A%3BFulton%2C+Janet+E%3BSchoenborn%2C+Charlotte+A%3BLoustalot%2C+Fleetwood&rft.aulast=Carlson&rft.aufirst=Susan&rft.date=2010-10-01&rft.volume=39&rft.issue=4&rft.spage=305&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2010.06.006 LA - English DB - PAIS Index N1 - Date revised - 2010-12-16 N1 - Last updated - 2016-09-28 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Physical fitness; Public health; United States; Adults; Health surveys DO - http://dx.doi.org/10.1016/j.amepre.2010.06.006 ER - TY - JOUR T1 - Pneumococcal Polysaccharide Vaccination Among Adults Aged 65 Years and Older, U.S., 1989-2008 AN - 815539615; 13870300 AB - The 23-valent pneumococcal polysaccharide vaccine (PPSV23) has been recommended for all people aged >=65 years in the U.S. since 1983; consistent surveillance for vaccine coverage has been conducted since 1989AB: To assess PPSV23 vaccination coverage among adults aged >=65 years in the U.S. Methods: The data were analyzed from the 1989, 1991, 1993-1995, and 1997-2008 National Health Interview Surveys in 2009. Multivariable logistic regression and predictive marginal analyses were conducted to identify factors independently associated with receiving PPSV23 in 2008. Missed opportunities for vaccination were also assessed. Results: Among people aged >=65 years, PPSV23 coverage increased from 14.1% in 1989 to 60.1% in 2008. On average, vaccination coverage increased by 3.5% annually during 1989-2000 compared with 1.0% during 2001-2008. In 2008, coverage was significantly higher for people aged 75-84 years (68.8%), and >=85 years (69.0%) compared with those aged 65-74 years (52.5%). Coverage was significantly higher for non-Hispanic whites (64.3%) compared with non-Hispanic blacks (44.6%) and those with Hispanic ethnicity (36.4%). Among people aged >=65 years who reported never receiving PPSV23, 90.6% reported at least one missed opportunity. Characteristics independently associated with increased likelihood of ever receiving PPSV23 were higher age, female, non-Hispanic white race/ethnicity, not employed, higher education level, more physician visits in the past year, hospitalized within past year, having Medicare and other supplemental health insurance, and having a chronic medical condition. Conclusions: National PPSV23 coverage among people aged >=65 years increased substantially until 2000, but the rate of increase was smaller after 2000 and coverage in 2008 remained well below the national Healthy People 2010 target of 90%. Increased efforts to avoid missed opportunities for pneumococcal vaccination are needed, especially among minority populations. JF - American Journal of Preventive Medicine AU - Lu, Peng-Jun AU - Nuorti, JPekka AD - Assessment Branch, Immunization Services Division, National Center for Immunization and Respiratory Diseases, CDC, Atlanta, Georgia, lhp8@cdc.gov Y1 - 2010/10// PY - 2010 DA - Oct 2010 SP - 287 EP - 295 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 39 IS - 4 SN - 0749-3797, 0749-3797 KW - Microbiology Abstracts B: Bacteriology KW - Streptococcus pneumoniae KW - Education KW - Age KW - Data processing KW - Vaccines KW - Polysaccharides KW - Vaccination KW - Ethnic groups KW - Races KW - J 02350:Immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/815539615?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Pneumococcal+Polysaccharide+Vaccination+Among+Adults+Aged+65+Years+and+Older%2C+U.S.%2C+1989-2008&rft.au=Lu%2C+Peng-Jun%3BNuorti%2C+JPekka&rft.aulast=Lu&rft.aufirst=Peng-Jun&rft.date=2010-10-01&rft.volume=39&rft.issue=4&rft.spage=287&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2010.06.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-11-01 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - Age; Education; Data processing; Vaccines; Polysaccharides; Vaccination; Races; Ethnic groups; Streptococcus pneumoniae DO - http://dx.doi.org/10.1016/j.amepre.2010.06.004 ER - TY - JOUR T1 - STRATEGIES USED BY COMMUNITY-BASED ORGANIZATIONS TO EVALUATE THEIR LOCALLY DEVELOPED HIV PREVENTION INTERVENTIONS: LESSONS LEARNED FROM THE CDC'S INNOVATIVE INTERVENTIONS PROJECT AN - 807290109; 13867188 AB - Community-based organizations (CBOs) play an important role in health promotion efforts and the delivery of HIV prevention interventions for at-risk minority populations. CBOs may also develop their own interventions but often lack the capacity or funds to rigorously evaluate them. The Innovative Interventions project of the Centers for Disease Control and Prevention (CDC) funded three CBOs to rigorously evaluate the efficacy of interventions they had developed and were delivering to Black women, Black men who have sex with men (MSM), and adolescent males in juvenile justice settings, respectively. The evaluation results have been reported elsewhere. This article describes operational issues that the CBOs identified as being particularly salient to their evaluations and the strategies they developed to address the issues and successfully complete their evaluations. These issues included the development of organizational capacity to conduct a rigorous outcome evaluation, difficulties with recruitment and retention of evaluation participants, and the use of process monitoring data to improve intervention delivery. The strategies described in this article can be used by CBOs when evaluating their locally developed HIV prevention interventions and may be of interest to funding agencies and researchers that collaborate with CBOs to evaluate their interventions. JF - AIDS Education and Prevention AU - Painter, T M AU - Ngalame, P M AU - Lucas, B AU - Lauby, J L AU - Herbst, J H AD - Centers for Disease Control and Prevention, Atlanta, GA, USA, tcp2@cdc.gov Y1 - 2010/10// PY - 2010 DA - Oct 2010 SP - 387 EP - 401 VL - 22 IS - 5 SN - 0899-9546, 0899-9546 KW - Risk Abstracts; Virology & AIDS Abstracts KW - Acquired immune deficiency syndrome KW - Data processing KW - Adolescence KW - Recruitment KW - homosexuality KW - Disease control KW - community involvement KW - Education KW - Human immunodeficiency virus KW - intervention KW - prevention KW - innovations KW - Adolescents KW - Sex KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/807290109?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+Education+and+Prevention&rft.atitle=STRATEGIES+USED+BY+COMMUNITY-BASED+ORGANIZATIONS+TO+EVALUATE+THEIR+LOCALLY+DEVELOPED+HIV+PREVENTION+INTERVENTIONS%3A+LESSONS+LEARNED+FROM+THE+CDC%27S+INNOVATIVE+INTERVENTIONS+PROJECT&rft.au=Painter%2C+T+M%3BNgalame%2C+P+M%3BLucas%2C+B%3BLauby%2C+J+L%3BHerbst%2C+J+H&rft.aulast=Painter&rft.aufirst=T&rft.date=2010-10-01&rft.volume=22&rft.issue=5&rft.spage=387&rft.isbn=&rft.btitle=&rft.title=AIDS+Education+and+Prevention&rft.issn=08999546&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-11-01 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - Data processing; Adolescence; Recruitment; Disease control; Sex; Education; Acquired immune deficiency syndrome; Human immunodeficiency virus; intervention; homosexuality; prevention; innovations; community involvement; Adolescents ER - TY - JOUR T1 - Increase in unintentional medication overdose deaths: Oklahoma, 1994-2006. AN - 755179456; 20837287 AB - During 1999-2006, rates of unintentional drug-related deaths increased 120% in the U.S. This report describes demographics and trends of unintentional medication overdose deaths among Oklahoma residents to target prevention strategies. Oklahoma medical examiner data regarding fatal unintentional poisonings involving at least one prescription or over-the-counter medication during 1994-2006 and opioid retail sales data during 1997-2006 were analyzed during 2008-2009 to determine demographic-specific rates of overdose deaths and changes in 3-year mean death rates. A total of 2112 fatal unintentional medication overdoses were identified (4.7 deaths/100,000 population) involving a median of two substances/decedent. The highest fatality rates occurred among men (5.9/100,000) and people aged 35-54 years (11/100,000). Crude overdose death rates increased sevenfold during the investigation period, peaking at 11/100,000 in 2006. Death rates increased more for women (ninefold) than men (sixfold); rates among residents of rural counties increased more (eightfold) than urban county rates (sixfold). Leading drug types involved in fatalities were opioids and anxiolytics. The individual drugs contributing most frequently included methadone (31%); hydrocodone (19%); alprazolam (15%); and oxycodone (15%). During 1997-2006, Oklahoma prescription opioid sales increased fourfold. Methadone was associated with the highest number of deaths per equianalgesic dose sold (23.3), whereas hydrocodone and oxycodone had the highest increases in deaths per equianalgesic dose sold (threefold increase each). Unintentional medication-related deaths are increasing in Oklahoma and often involve multiple substances. Substances most frequently contributing to deaths were prescription opioid analgesics. Prevention strategies should target people aged 35-54 years and emphasize the dangers of coingesting substances and misusing prescription pain medications. Published by Elsevier Inc. JF - American journal of preventive medicine AU - Piercefield, Emily AU - Archer, Pam AU - Kemp, Philip AU - Mallonee, Sue AD - CDC, CDC/OWCD/CDD/PMR, 1600 Clifton Road NE, Mailstop E-92, Atlanta GA 30333, USA. epiercefıeld@cdc.gov Y1 - 2010/10// PY - 2010 DA - October 2010 SP - 357 EP - 363 VL - 39 IS - 4 KW - Analgesics, Opioid KW - 0 KW - Pharmaceutical Preparations KW - Index Medicus KW - Pharmaceutical Preparations -- administration & dosage KW - Young Adult KW - Age Factors KW - Urban Population -- statistics & numerical data KW - Sex Factors KW - Rural Population -- statistics & numerical data KW - Humans KW - Aged KW - Child KW - Drug Overdose -- epidemiology KW - Child, Preschool KW - Infant KW - Drug Overdose -- mortality KW - Risk Factors KW - Adult KW - Middle Aged KW - Adolescent KW - Oklahoma -- epidemiology KW - Male KW - Cause of Death -- trends KW - Female KW - Analgesics, Opioid -- poisoning KW - Drug-Related Side Effects and Adverse Reactions KW - Analgesics, Opioid -- administration & dosage UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/755179456?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+journal+of+preventive+medicine&rft.atitle=Increase+in+unintentional+medication+overdose+deaths%3A+Oklahoma%2C+1994-2006.&rft.au=Piercefield%2C+Emily%3BArcher%2C+Pam%3BKemp%2C+Philip%3BMallonee%2C+Sue&rft.aulast=Piercefield&rft.aufirst=Emily&rft.date=2010-10-01&rft.volume=39&rft.issue=4&rft.spage=357&rft.isbn=&rft.btitle=&rft.title=American+journal+of+preventive+medicine&rft.issn=1873-2607&rft_id=info:doi/10.1016%2Fj.amepre.2010.05.016 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-01-04 N1 - Date created - 2010-09-14 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.amepre.2010.05.016 ER - TY - JOUR T1 - Pregnancy-associated listeriosis. AN - 748965839; 20158931 AB - Infection by Listeria monocytogenes in pregnant women may result in fetal loss or invasive disease in the newborn. We examined listeriosis cases reported through the U.S. Listeria Initiative during 2004-2007. Cases were classified as pregnancy-associated if illness occurred in a pregnant woman or an infant aged <28 days. Of 758 reported Listeria cases, 128 (16.9%) were pregnancy-associated. Maternal infection resulted in four neonatal deaths and 26 (20.3%) fetal losses. Invasive illnesses in newborns (n=85) were meningitis (32.9%) and sepsis (36.5%). Pregnant women with Listeria were more likely to report Hispanic ethnicity (52.8% vs. 25.6%, respectively; OR 3.3 95% CI 2.2-4.8) than mothers giving live birth in the USA during 2005 and were more likely to report consumption of Mexican-style cheese (OR 2.6, 95% CI 1.6-4.2) than were non-pregnant patients with Listeria infection. Pregnant woman comprised a considerable proportion of reported listeriosis cases. Further declines in pregnancy-associated listeriosis will require education about avoiding high-risk foods, and continued regulatory and industry efforts to decrease Listeria in foods. JF - Epidemiology and infection AU - Jackson, K A AU - Iwamoto, M AU - Swerdlow, D AD - Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. gqv8@cdc.gov Y1 - 2010/10// PY - 2010 DA - October 2010 SP - 1503 EP - 1509 VL - 138 IS - 10 KW - Index Medicus KW - Young Adult KW - Foodborne Diseases -- epidemiology KW - Humans KW - Foodborne Diseases -- microbiology KW - Infant, Newborn KW - Feeding Behavior KW - Pregnancy KW - Ethnic Groups KW - Risk Factors KW - Adult KW - Incidence KW - Middle Aged KW - Adolescent KW - United States -- epidemiology KW - Female KW - Pregnancy Complications, Infectious -- microbiology KW - Listeriosis -- epidemiology KW - Infant, Newborn, Diseases -- epidemiology KW - Listeria monocytogenes -- isolation & purification KW - Pregnancy Complications, Infectious -- epidemiology KW - Listeriosis -- microbiology KW - Infant, Newborn, Diseases -- mortality KW - Infant, Newborn, Diseases -- microbiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/748965839?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+infection&rft.atitle=Pregnancy-associated+listeriosis.&rft.au=Jackson%2C+K+A%3BIwamoto%2C+M%3BSwerdlow%2C+D&rft.aulast=Jackson&rft.aufirst=K&rft.date=2010-10-01&rft.volume=138&rft.issue=10&rft.spage=1503&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+infection&rft.issn=1469-4409&rft_id=info:doi/10.1017%2FS0950268810000294 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-09-09 N1 - Date created - 2010-08-19 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1017/S0950268810000294 ER - TY - JOUR T1 - Racial and ethnic disparities in work-related injuries and socio-economic resources among nursing assistants employed in US nursing homes AN - 1017967055; 16691623 AB - Background We aimed to estimate the proportion of nursing assistants (NAs) in the US with work-related injuries and insufficient socio-economic resources by race/ethnicity. Methods Data from the 2004 National Nursing Assistant Survey (NNAS), a nationally representative sample survey of NAs employed in United States nursing homes, were analyzed accounting for the complex survey design. Results Among 2,880 participants, 44% reported 'scratch, open wounds, or cuts' followed by 'back injuries' (17%), 'black eyes or other types of bruising' (16%), and 'human bites' (12%). When compared to non-Hispanic white NAs, the adjusted rate ratio (RR) for wound/cut was 0.74 for non-Hispanic black NAs (95% confidence interval [CI]: 0.65-0.85). RRs for black eyes/bruises were 0.18 for non-Hispanic black NAs (95% CI: 0.12-0.26), and 0.55 for Hispanic NAs (95% CI: 0.37-0.82). Conclusions Minority racial and ethnic groups were less likely to report having experienced injuries compared with non-Hispanic white NAs. Future research should focus on identifying preventable risk factors, such as differences by race and ethnicity in the nature of NA jobs and the extent of their engagement in assisting patients with activities of daily living. Am. J. Ind. Med. 53:951-959, 2010. ? 2010 Wiley-Liss, Inc. JF - American Journal of Industrial Medicine AU - Tak, Sangwoo AU - Alterman, Toni AU - Baron, Sherry AU - Calvert, Geoffrey M Y1 - 2010/10// PY - 2010 DA - Oct 2010 SP - 951 EP - 959 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 53 IS - 10 SN - 1097-0274, 1097-0274 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Ethnic groups KW - Injuries KW - Risk factors KW - Socioeconomics KW - bites KW - USA KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1017967055?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Racial+and+ethnic+disparities+in+work-related+injuries+and+socio-economic+resources+among+nursing+assistants+employed+in+US+nursing+homes&rft.au=Tak%2C+Sangwoo%3BAlterman%2C+Toni%3BBaron%2C+Sherry%3BCalvert%2C+Geoffrey+M&rft.aulast=Tak&rft.aufirst=Sangwoo&rft.date=2010-10-01&rft.volume=53&rft.issue=10&rft.spage=951&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=10970274&rft_id=info:doi/10.1002%2Fajim.20852 L2 - http://onlinelibrary.wiley.com/doi/10.1002/ajim.20852/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2012-06-01 N1 - SubjectsTermNotLitGenreText - Injuries; Risk factors; bites; Socioeconomics; Ethnic groups; USA DO - http://dx.doi.org/10.1002/ajim.20852 ER - TY - JOUR T1 - Interpreting NHANES biomonitoring data, cadmium. AN - 748954823; 20447450 AB - Cadmium (Cd) occurs naturally in the environment and the general population's exposure to it is predominantly through diet. Chronic Cd exposure is a public health concern because Cd is a known carcinogen; it accumulates in the body and causes kidney damage. The National Health and Nutritional Examination Survey (NHANES) has measured urinary Cd; the 2003-2004 NHANES survey cycle reported estimates for 2257 persons aged 6 years and older in the Fourth National Report on Human Exposure to Environmental Chemicals. As part of translational research to make computerized models accessible to health risk assessors we re-coded a cadmium model in Berkeley Madonna simulation language. This model was used in our computational toxicology laboratory to predict the urinary excretion of cadmium. The model simulated the NHANES-measured data very well from ages 6 to 60+ years. An unusual increase in Cd urinary excretion was observed among 6-11-year-olds, followed by a continuous monotonic rise into the seventh decade of life. This observation was also made in earlier studies that could be life stage-related and a function of anatomical and phsysiological changes occurring during this period of life. Urinary excretion of Cd was approximately twofold higher among females than males in all age groups. The model describes Cd's cumulative nature in humans and accommodates the observed variation in exposure/uptake over the course of a lifetime. Such models may be useful for interpreting biomonitoring data and risk assessment. Published by Elsevier Ireland Ltd. JF - Toxicology letters AU - Ruiz, Patricia AU - Mumtaz, Moiz AU - Osterloh, John AU - Fisher, Jeffrey AU - Fowler, Bruce A AD - Agency for Toxic Substances and Disease Registry, Atlanta, GA 30333, USA. pruiz@cdc.gov Y1 - 2010/09/15/ PY - 2010 DA - 2010 Sep 15 SP - 44 EP - 48 VL - 198 IS - 1 KW - Environmental Pollutants KW - 0 KW - Cadmium KW - 00BH33GNGH KW - Index Medicus KW - Young Adult KW - Humans KW - Adult KW - Data Interpretation, Statistical KW - Middle Aged KW - Child KW - Diet KW - Adolescent KW - Male KW - Female KW - Environmental Monitoring KW - Environmental Exposure -- statistics & numerical data KW - Cadmium -- urine KW - Cadmium -- analysis KW - Environmental Exposure -- analysis KW - Nutrition Surveys KW - Environmental Pollutants -- urine KW - Environmental Pollutants -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/748954823?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+letters&rft.atitle=Interpreting+NHANES+biomonitoring+data%2C+cadmium.&rft.au=Ruiz%2C+Patricia%3BMumtaz%2C+Moiz%3BOsterloh%2C+John%3BFisher%2C+Jeffrey%3BFowler%2C+Bruce+A&rft.aulast=Ruiz&rft.aufirst=Patricia&rft.date=2010-09-15&rft.volume=198&rft.issue=1&rft.spage=44&rft.isbn=&rft.btitle=&rft.title=Toxicology+letters&rft.issn=1879-3169&rft_id=info:doi/10.1016%2Fj.toxlet.2010.04.022 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-09-10 N1 - Date created - 2010-08-16 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.toxlet.2010.04.022 ER - TY - JOUR T1 - Formulation and stability of a novel artificial human sweat under conditions of storage and use AN - 877589600; 13668023 AB - A limitation of most artificial sweat formulations used for in vitro assessment of chemical release from materials in contact with skin have little biological relevance to human sweat. The purposes of this paper are to provide guidance for preparation of a novel artificial sweat with chemical constituents at concentrations that match human sweat and to characterize chemical stability. The artificial sweat was characterized under conditions of use (with and without sebum at 36AC) and storage (without sebum at a4, 4, and 23AC) over 28days by gas chromatography-mass spectroscopy, high-performance liquid chromatography, enzymatic assay kits, and ion-selective electrodes. Seven indicator constituents were tracked: sodium, chloride, glucose, lactic acid, urea, pantothenic acid, and alanine. With or without sebum at 36AC, the sweat solvent was chemically stable for 14days. Storage by refrigeration at 4AC retained the chemical integrity of the solvent longest. Based on these results, the solvent should be used within 14days of preparation. The artificial sweat model presented herein is most similar to human sweat and has applications as a dissolution solvent, donor solution in diffusion cells, or vehicle for patch testing. This sweat model may aid researchers in understanding potential release and percutaneous absorption of chemicals in contact with human skin surface liquids. JF - Toxicology In Vitro AU - Harvey, Christopher J AU - LeBouf, Ryan F AU - Stefaniak, Aleksandr B AD - National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA, AStefaniak@cdc.gov Y1 - 2010/09// PY - 2010 DA - Sep 2010 SP - 1790 EP - 1796 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK VL - 24 IS - 6 SN - 0887-2333, 0887-2333 KW - Toxicology Abstracts KW - Alanine KW - Sweat KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/877589600?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+In+Vitro&rft.atitle=Formulation+and+stability+of+a+novel+artificial+human+sweat+under+conditions+of+storage+and+use&rft.au=Harvey%2C+Christopher+J%3BLeBouf%2C+Ryan+F%3BStefaniak%2C+Aleksandr+B&rft.aulast=Harvey&rft.aufirst=Christopher&rft.date=2010-09-01&rft.volume=24&rft.issue=6&rft.spage=1790&rft.isbn=&rft.btitle=&rft.title=Toxicology+In+Vitro&rft.issn=08872333&rft_id=info:doi/10.1016%2Fj.tiv.2010.06.016 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-10-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Sweat DO - http://dx.doi.org/10.1016/j.tiv.2010.06.016 ER - TY - JOUR T1 - A Comparison of Aboveground and Belowground Populations of Culex pipiens (Diptera: Culicidae) Mosquitoes in Chicago, Illinois, and New York City, New York, using Microsatellites AN - 851462327; 14078015 AB - Aboveground and belowground populations of the mosquito Culex pipiens L. are traditionally classified as form pipiens and form molestus, respectively, and gene flow between forms is thought to be limited. Relatively few f. molestus populations have been found in the United States, which has hindered their study in North America. In this study, we used microsatellites to characterize a newly discovered population of f. molestus in Chicago, IL, and compared levels of genetic diversity and differentiation in aboveground and belowground populations from Chicago and New York City, NY. Levels of genetic diversity, as measured by expected heterozygosity and allelic richness, were markedly lower in both f. molestus populations. Allele frequencies were distinctly different between the two f. molestus populations, and some alleles were present in one belowground population and not the other. Pairwise FST values between populations indicated that f. molestus populations were highly divergent from each other, as well as from their associated aboveground populations. Cluster analysis suggested the most likely number of groups was three, with the four f. pipiens populations in one cluster, and each of the f. molestus populations in its own cluster. Admixture analysis detected a low number of hybrids, 8%, between forms. We also tested the efficacy of two assays purported to distinguish between the forms, the CQ11 assay and a restriction fragment-length polymorphism assay of the COI gene, and found neither assay reliable in this regard. Our findings support the hypothesis that f. molestus populations in Chicago and New York City arose from local aboveground populations. JF - Journal of Medical Entomology AU - Kothera, Linda AU - Godsey, Marvin AU - Mutebi, John-Paul AU - Savage, Harry M Y1 - 2010/09// PY - 2010 DA - Sep 2010 SP - 805 EP - 813 PB - Entomological Society of America, 9301 Annapolis Rd. Lanham MD 20706 USA VL - 47 IS - 5 SN - 0022-2585, 0022-2585 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Entomology Abstracts KW - USA, Illinois, Chicago KW - Geographical distribution KW - Allelles KW - Gene polymorphism KW - Nucleotide sequence KW - Genetic diversity KW - Differentiation KW - Population genetics KW - Comparative studies KW - USA, New York, New York City KW - Hybrids KW - Gene flow KW - COI protein KW - Aquatic insects KW - USA, Illinois KW - Microsatellites KW - Culicidae KW - Biopolymorphism KW - Heterozygosity KW - Culex pipiens KW - DNA KW - Gene frequency KW - Diptera KW - Q1 08443:Population genetics KW - Z 05360:Genetics and Evolution KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/851462327?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Medical+Entomology&rft.atitle=A+Comparison+of+Aboveground+and+Belowground+Populations+of+Culex+pipiens+%28Diptera%3A+Culicidae%29+Mosquitoes+in+Chicago%2C+Illinois%2C+and+New+York+City%2C+New+York%2C+using+Microsatellites&rft.au=Kothera%2C+Linda%3BGodsey%2C+Marvin%3BMutebi%2C+John-Paul%3BSavage%2C+Harry+M&rft.aulast=Kothera&rft.aufirst=Linda&rft.date=2010-09-01&rft.volume=47&rft.issue=5&rft.spage=805&rft.isbn=&rft.btitle=&rft.title=Journal+of+Medical+Entomology&rft.issn=00222585&rft_id=info:doi/10.1603%2FME10031 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-02-01 N1 - Number of references - 54 N1 - Last updated - 2014-05-29 N1 - SubjectsTermNotLitGenreText - Comparative studies; Population genetics; Geographical distribution; Allelles; Nucleotide sequence; DNA; Genetic diversity; Biopolymorphism; Aquatic insects; Differentiation; Hybrids; Gene polymorphism; Gene flow; Microsatellites; Gene frequency; COI protein; Heterozygosity; Culex pipiens; Culicidae; Diptera; USA, Illinois, Chicago; USA, New York, New York City; USA, Illinois DO - http://dx.doi.org/10.1603/ME10031 ER - TY - JOUR T1 - Coxiella burnetii Infection of a Steller Sea Lion (Eumetopias jubatus) Found in Washington State AN - 807261527; 13664890 AB - A pregnant sea lion stranded in the State of Washington was found to have placentitis caused by a unique strain of Coxiella burnetii. This is the first description of coxiellosis in a sea lion and suggests that exposure to sea lions may be a risk factor for contracting Q fever. JF - Journal of Clinical Microbiology AU - Kersh, Gilbert J AU - Lambourn, Dyanna M AU - Self, Joshua S AU - Akmajian, Adrianne M AU - Stanton, James B AU - Baszler, Timothy V AU - Raverty, Stephen A AU - Massung, Robert F AD - Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, gkersh@cdc.gov Y1 - 2010/09// PY - 2010 DA - September 2010 SP - 3428 EP - 3431 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 48 IS - 9 SN - 0095-1137, 0095-1137 KW - Oceanic Abstracts; ASFA 1: Biological Sciences & Living Resources; Microbiology Abstracts B: Bacteriology KW - Marine KW - Coxiella burnetii KW - Eumetopias jubatus KW - Risk factors KW - Marine mammals KW - Microbiology KW - INE, USA, Washington KW - Infection KW - Q fever KW - Pregnancy KW - O 1070:Ecology/Community Studies KW - Q1 08484:Species interactions: parasites and diseases KW - J 02450:Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/807261527?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Coxiella+burnetii+Infection+of+a+Steller+Sea+Lion+%28Eumetopias+jubatus%29+Found+in+Washington+State&rft.au=Kersh%2C+Gilbert+J%3BLambourn%2C+Dyanna+M%3BSelf%2C+Joshua+S%3BAkmajian%2C+Adrianne+M%3BStanton%2C+James+B%3BBaszler%2C+Timothy+V%3BRaverty%2C+Stephen+A%3BMassung%2C+Robert+F&rft.aulast=Kersh&rft.aufirst=Gilbert&rft.date=2010-09-01&rft.volume=48&rft.issue=9&rft.spage=3428&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.00758-10 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-11-01 N1 - Number of references - 16 N1 - Last updated - 2016-10-26 N1 - SubjectsTermNotLitGenreText - Marine mammals; Microbiology; Risk factors; Infection; Q fever; Pregnancy; Coxiella burnetii; Eumetopias jubatus; INE, USA, Washington; Marine DO - http://dx.doi.org/10.1128/JCM.00758-10 ER - TY - JOUR T1 - Survey of Knowledge, Attitudes, and Practice Management Patterns of Atlanta-Area Obstetricians Regarding Stillbirth AN - 772251767; 201029919 AB - Objective Existing surveillance data on fetal death certificates are suboptimal for conducting reliable epidemiologic studies on stillbirth. The objective of this survey was to better understand the factors potentially affecting the quality of data collected on stillbirths among a defined population. Methods A survey was mailed to all physicians (n = 661) listed in the July 2007 version of the American Medical Association master file with a primary specialty of obstetrics/gynecology and a mailing address within five counties in metropolitan Atlanta. Results A total of 487 physicians met eligibility criteria: 279 returned the survey, 179 did not return the survey, and 29 were returned as unable to locate. Two respondents returned incomplete surveys, leaving 277 participants for the final analysis. Respondents reported seeing an average of six stillbirths per year. A cause of death was not identified in two thirds of cases. Almost half (46.8%) of participants responded that 20 weeks was the minimum gestational age defining stillbirth, whereas 33.1% responded that it was 24 weeks. A majority (92.6%) responded that a standardized definition for stillbirth should be adopted. More than 80% agreed that a comprehensive evaluation was important to identify a cause of death, and 91.9% agreed that the use of a standardized protocol for post-mortem stillbirth evaluation would be helpful. A majority also agreed that ongoing surveillance of stillbirths and a national research agenda on causes of stillbirth are important. Conclusion Comprehensive educational and awareness efforts for obstetricians and other related health care personnel are needed to further improve on the data collected for surveillance purposes on stillbirth. [Copyright Jacobs Institute of Women's Health; published by Elsevier Science Inc.] JF - Women's Health Issues AU - Duke, Wes AU - Shin, Mikyong AU - Correa, Adolfo AU - Alverson, Clinton J AD - Division of Birth Defects and Developmental Disabilities, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia cduke@cdc.gov Y1 - 2010/09// PY - 2010 DA - September 2010 SP - 366 EP - 370 PB - Elsevier Science, New York NY VL - 20 IS - 5 SN - 1049-3867, 1049-3867 KW - Death KW - Gestational age KW - Doctors KW - Stillbirths KW - Obstetricians KW - Surveillance KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/772251767?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Women%27s+Health+Issues&rft.atitle=Survey+of+Knowledge%2C+Attitudes%2C+and+Practice+Management+Patterns+of+Atlanta-Area+Obstetricians+Regarding+Stillbirth&rft.au=Duke%2C+Wes%3BShin%2C+Mikyong%3BCorrea%2C+Adolfo%3BAlverson%2C+Clinton+J&rft.aulast=Duke&rft.aufirst=Wes&rft.date=2010-09-01&rft.volume=20&rft.issue=5&rft.spage=366&rft.isbn=&rft.btitle=&rft.title=Women%27s+Health+Issues&rft.issn=10493867&rft_id=info:doi/10.1016%2Fj.whi.2010.06.004 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-11-11 N1 - Last updated - 2016-09-27 N1 - CODEN - WHISEH N1 - SubjectsTermNotLitGenreText - Stillbirths; Surveillance; Doctors; Obstetricians; Death; Gestational age DO - http://dx.doi.org/10.1016/j.whi.2010.06.004 ER - TY - JOUR T1 - Sedentary behavior, physical activity, and concentrations of insulin among US adults AN - 762269685; 13717247 AB - Time spent watching television has been linked to obesity, metabolic syndrome, and diabetes, all conditions characterized to some degree by hyperinsulinemia and insulin resistance. However, limited evidence relates screen time (watching television or using a computer) directly to concentrations of insulin. We examined the cross-sectional associations between time spent watching television or using a computer, physical activity, and serum concentrations of insulin using data from 2800 participants aged at least 20 years of the 2003-2006 National Health and Nutrition Examination Survey. The amount of time spent watching television and using a computer as well as physical activity was self-reported. The unadjusted geometric mean concentration of insulin increased from 6.2 kU/mL among participants who did not watch television to 10.0 kU/mL among those who watched television for 5 or more hours per day (P = .001). After adjustment for age, sex, race or ethnicity, educational status, concentration of cotinine, alcohol intake, physical activity, waist circumference, and body mass index using multiple linear regression analysis, the log-transformed concentrations of insulin were significantly and positively associated with time spent watching television (P = < .001). Reported time spent using a computer was significantly associated with log-transformed concentrations of insulin before but not after accounting for waist circumference and body mass index. Leisure-time physical activity but not transportation or household physical activity was significantly and inversely associated with log-transformed concentrations of insulin. Sedentary behavior, particularly the amount of time spent watching television, may be an important modifiable determinant of concentrations of insulin. JF - Metabolism AU - Ford, Earl S AU - Li, Chaoyang AU - Zhao, Guixiang AU - Pearson, William S AU - Tsai, James AU - Churilla, James R AD - Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA, eford@cdc.gov Y1 - 2010/09// PY - 2010 DA - Sep 2010 SP - 1268 EP - 1275 PB - W.B. Saunders Company, Periodicals Order Fulfillment Dept. Orlando, FL 32887-4800 USA VL - 59 IS - 9 SN - 0026-0495, 0026-0495 KW - Physical Education Index KW - Alcohol KW - Hormones KW - PE:030 UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/762269685?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Metabolism&rft.atitle=Sedentary+behavior%2C+physical+activity%2C+and+concentrations+of+insulin+among+US+adults&rft.au=Ford%2C+Earl+S%3BLi%2C+Chaoyang%3BZhao%2C+Guixiang%3BPearson%2C+William+S%3BTsai%2C+James%3BChurilla%2C+James+R&rft.aulast=Ford&rft.aufirst=Earl&rft.date=2010-09-01&rft.volume=59&rft.issue=9&rft.spage=1268&rft.isbn=&rft.btitle=&rft.title=Metabolism&rft.issn=00260495&rft_id=info:doi/10.1016%2Fj.metabol.2009.11.020 LA - English DB - Physical Education Index N1 - Date revised - 2010-11-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Hormones DO - http://dx.doi.org/10.1016/j.metabol.2009.11.020 ER - TY - JOUR T1 - Federal Funding for Reporting Cases of HIV Infection in the United States, 2006 AN - 758117813; 2010-616594 AB - Objective. The Centers for Disease Control and Prevention (CDC) provides funding for human immunodeficiency virus (HIV) surveillance in 65 areas (states, cities, and U.S. dependent areas). We determined the amount of CDC funding per reported case of HIV infection and examined factors associated with differences in funding per reported case across areas. Methods. We derived HIV data from the HIV/AIDS Reporting System (HARS) database. Budget numbers were based on award letters to health departments. We performed multivariate linear regression for all areas and for areas of low, moderate, and moderate-to-high morbidity. Results. Mean funding per case reported was $1,520, $441, and ?411 in areas of low, moderate, and moderate-to-high morbidity, respectively. In low morbidity areas, funding per case decreased as log total cases increased. For moderate and moderate-to-high morbidity areas, funding per case fell as log total cases increased, but increased in accordance with an area's population and the proportion of that population residing in an urban setting. The models for low, moderate, and moderate-to-high morbidity predicted funding per case as 1,490, 423, and $390, respectively. Conclusions. Economies of scale were evident. The amount of CDC core surveillance funding per case reported was significantly associated with the total number of cases in an area and, depending on morbidity, with total population and percentage of that population residing in an urban setting. Adapted from the source document. JF - Public Health Reports AU - Page, Matthew J AU - McDavid Harrison, Kathleen AU - Wei, Xiangming AU - Hall, H Irene AD - National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention/HIV Incidence and Case Surveillance Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd. NE, MS E-07, Atlanta, GA 30333; tel. 404-639-0468; fax 404-639-8603 Y1 - 2010/09// PY - 2010 DA - September 2010 SP - 718 EP - 727 PB - Oxford University Press, UK VL - 125 IS - 5 SN - 0033-3549, 0033-3549 KW - Health conditions and policy - Diseases and disorders KW - Law and ethics - Criminal law KW - Government - Internal security KW - Business and service sector - Business finance KW - Health conditions and policy - Health and health policy KW - United States KW - Finance KW - Human immunodeficiency virus KW - Diseases KW - Surveillance KW - Public health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/758117813?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Public+Health+Reports&rft.atitle=Federal+Funding+for+Reporting+Cases+of+HIV+Infection+in+the+United+States%2C+2006&rft.au=Page%2C+Matthew+J%3BMcDavid+Harrison%2C+Kathleen%3BWei%2C+Xiangming%3BHall%2C+H+Irene&rft.aulast=Page&rft.aufirst=Matthew&rft.date=2010-09-01&rft.volume=125&rft.issue=5&rft.spage=718&rft.isbn=&rft.btitle=&rft.title=Public+Health+Reports&rft.issn=00333549&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2010-10-12 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Human immunodeficiency virus; United States; Finance; Public health; Surveillance; Diseases ER - TY - JOUR T1 - Characterization of Novel Brucella Strains Originating from Wild Native Rodent Species in North Queensland, Australia AN - 755133428; 13628096 AB - We report on the characterization of a group of seven novel Brucella strains isolated in 1964 from three native rodent species in North Queensland, Australia, during a survey of wild animals. The strains were initially reported to be Brucella suis biovar 3 on the basis of microbiological test results. Our results indicated that the rodent strains had microbiological traits distinct from those of B. suis biovar 3 and all other Brucella spp. To reinvestigate these rodent strains, we sequenced the 16S rRNA, recA, and rpoB genes and nine housekeeping genes and also performed multiple-locus variable-number tandem-repeat (VNTR) analysis (MLVA). The rodent strains have a unique 16S rRNA gene sequence compared to the sequences of the classical Brucella spp. Sequence analysis of the recA, rpoB, and nine housekeeping genes reveals that the rodent strains are genetically identical to each other at these loci and divergent from any of the currently described Brucella sequence types. However, all seven of the rodent strains do exhibit distinctive allelic MLVA profiles, although none demonstrated an amplicon for VNTR 07, whereas the other Brucella spp. did. Phylogenetic analysis of the MLVA data reveals that the rodent strains form a distinct clade separate from the classical Brucella spp. Furthermore, whole-genome sequence comparison using the maximal unique exact matches index (MUMi) demonstrated a high degree of relatedness of one of the seven rodent Brucella strains (strain NF 2653) to another Australian rodent Brucella strain (strain 83-13). Our findings strongly suggest that this group of Brucella strains isolated from wild Australian rodents defines a new species in the Brucella genus. JF - Applied and Environmental Microbiology AU - Tiller, Rebekah V AU - Gee, Jay E AU - Frace, Michael A AU - Taylor, Trevor K AU - Setubal, Joao C AU - Hoffmaster, Alex R AU - De Barun, K AD - Centers for Disease Control and Prevention, Atlanta, Georgia 30333, bkd1@cdc.gov Y1 - 2010/09// PY - 2010 DA - Sep 2010 SP - 5837 EP - 5845 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 76 IS - 17 SN - 0099-2240, 0099-2240 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology KW - Data processing KW - Brucella suis KW - RecA protein KW - J 02310:Genetics & Taxonomy KW - A 01340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/755133428?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Characterization+of+Novel+Brucella+Strains+Originating+from+Wild+Native+Rodent+Species+in+North+Queensland%2C+Australia&rft.au=Tiller%2C+Rebekah+V%3BGee%2C+Jay+E%3BFrace%2C+Michael+A%3BTaylor%2C+Trevor+K%3BSetubal%2C+Joao+C%3BHoffmaster%2C+Alex+R%3BDe+Barun%2C+K&rft.aulast=Tiller&rft.aufirst=Rebekah&rft.date=2010-09-01&rft.volume=76&rft.issue=17&rft.spage=5837&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/10.1128%2FAEM.00620-10 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-09-01 N1 - Number of references - 1 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - RecA protein; Brucella suis DO - http://dx.doi.org/10.1128/AEM.00620-10 ER - TY - JOUR T1 - Assessment of Pandemic and Seasonal Influenza A (H1N1) Virus Susceptibility to Neuraminidase Inhibitors in Three Enzyme Activity Inhibition Assays AN - 754894613; 13527128 AB - The neuraminidase inhibitors (NAIs) zanamivir and oseltamivir are currently the only antiviral drugs effective for the treatment and prophylaxis of 2009 pandemic influenza A (H1N1) virus infections. The proven potential of these viruses to acquire NAI resistance during treatment emphasizes the need to assess their NAI susceptibility. The 50% inhibitory concentrations (IC50s) are known to vary depending on the neuraminidase inhibition (NI) test used; however, few side-by-side comparisons of different NI assays have been done. In the present study, a panel of 11 isolates representing 2009 seasonal and pandemic influenza H1N1 viruses, including oseltamivir-resistant H275Y variants, were tested in three functional NI assays: chemiluminescent (CL), fluorescent (FL), and colorimetric (CM). The sensitivities of the viruses to zanamivir, oseltamivir, and three investigational NAIs (peramivir, R-125489, and A-315675) were assessed. All isolates with the exception of H275Y variants were sensitive to all five NAIs by all three NI assays. The H275Y variants showed substantially elevated IC50s against oseltamivir and peramivir. The three NI assays generally yielded consistent results; thus, the choice of NI assay does not appear to affect conclusions based on drug susceptibility surveillance. Each assay, however, offers certain advantages compared to the others: the CL assay required less virus volume and the FL assay provided the greatest difference in the IC50s between the wild type and the variants, whereas the IC50s obtained from the CM assay may be the most predictive of the drug concentrations needed to inhibit enzyme activity in humans. It would be desirable to develop an NI assay which combines the advantages of all three currently available assays but which lacks their shortcomings. JF - Antimicrobial Agents & Chemotherapy AU - Nguyen, Ha T AU - Sheu, Tiffany G AU - Mishin, Vasiliy P AU - Klimov, Alexander I AU - Gubareva, Larisa V AD - Virus Surveillance and Diagnosis Branch, Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, lgubareva@cdc.gov Y1 - 2010/09// PY - 2010 DA - Sep 2010 SP - 3671 EP - 3677 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 54 IS - 9 SN - 0066-4804, 0066-4804 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Virology & AIDS Abstracts KW - pandemics KW - Antiviral agents KW - Exo-a-sialidase KW - Prophylaxis KW - Enzymes KW - Colorimetry KW - Infection KW - Zanamivir KW - Oseltamivir KW - A 01340:Antibiotics & Antimicrobials KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754894613?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Assessment+of+Pandemic+and+Seasonal+Influenza+A+%28H1N1%29+Virus+Susceptibility+to+Neuraminidase+Inhibitors+in+Three+Enzyme+Activity+Inhibition+Assays&rft.au=Nguyen%2C+Ha+T%3BSheu%2C+Tiffany+G%3BMishin%2C+Vasiliy+P%3BKlimov%2C+Alexander+I%3BGubareva%2C+Larisa+V&rft.aulast=Nguyen&rft.aufirst=Ha&rft.date=2010-09-01&rft.volume=54&rft.issue=9&rft.spage=3671&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.00581-10 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-09-01 N1 - Number of references - 39 N1 - Last updated - 2015-09-30 N1 - SubjectsTermNotLitGenreText - pandemics; Antiviral agents; Prophylaxis; Exo-a-sialidase; Colorimetry; Enzymes; Infection; Zanamivir; Oseltamivir DO - http://dx.doi.org/10.1128/AAC.00581-10 ER - TY - JOUR T1 - Cytomegalovirus seroconversion rates and risk factors: implications for congenital CMV AN - 1017968894; 16702703 AB - Congenital CMV infection is caused by in utero mother-to-fetus transmission and is a leading cause of birth defects and developmental disabilities. The highest risk of disability is to children born to women who have a primary infection during pregnancy, which can be detected by measuring seroconversion. We reviewed studies that reported rates of CMV seroconversion in different populations. Among pregnant women, annual seroconversion rates typically ranged from 1 to 7% (summary annual rate=2.3%, 95% CI=2.1-2.4%). Healthcare workers, including those caring for infants and children, had seroconversion rates similar to pregnant women (summary annual rate=2.3%, 95% CI=1.9-2.9%). Among day-care providers, seroconversion rates ranged from 0 to 12.5% (summary annual rate=8.5%, 95% CI=6.1-11.6%). Parents whose child was not shedding CMV were much less likely to seroconvert (summary annual rate=2.1%, 95% CI=0.3-6.8%) than were parents who had a child shedding CMV (summary annual rate=24%, 95% CI=18-30%). Nevertheless, over the course of a year, most parents exposed to a CMV-shedding child do not become infected. Other groups with elevated risk included families with a CMV-shedding member, female minority adolescents and women attending sexually transmitted disease clinics. The relatively low rate of CMV seroconversion in most populations is encouraging for behavioural interventions and for vaccine strategies attempting to prevent infection during pregnancy. Published in 2010 by John Wiley & Sons, Ltd. JF - Reviews in Medical Virology AU - Hyde, Terri B AU - Schmid, D Scott AU - Cannon, Michael J Y1 - 2010/09// PY - 2010 DA - Sep 2010 SP - 311 EP - 326 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 20 IS - 5 SN - 1099-1654, 1099-1654 KW - Risk Abstracts; Virology & AIDS Abstracts KW - Adolescence KW - Children KW - Congenital defects KW - Disabilities KW - Infants KW - Infection KW - Intervention KW - Medical personnel KW - Pregnancy KW - Reviews KW - Risk factors KW - Seroconversion KW - Sexually transmitted diseases KW - Sexually-transmitted diseases KW - Vaccines KW - Cytomegalovirus KW - R2 23060:Medical and environmental health KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1017968894?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Reviews+in+Medical+Virology&rft.atitle=Cytomegalovirus+seroconversion+rates+and+risk+factors%3A+implications+for+congenital+CMV&rft.au=Hyde%2C+Terri+B%3BSchmid%2C+D+Scott%3BCannon%2C+Michael+J&rft.aulast=Hyde&rft.aufirst=Terri&rft.date=2010-09-01&rft.volume=20&rft.issue=5&rft.spage=311&rft.isbn=&rft.btitle=&rft.title=Reviews+in+Medical+Virology&rft.issn=10991654&rft_id=info:doi/10.1002%2Frmv.659 L2 - http://onlinelibrary.wiley.com/doi/10.1002/rmv.659/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2013-01-11 N1 - SubjectsTermNotLitGenreText - Sexually-transmitted diseases; Reviews; Adolescence; Risk factors; Congenital defects; Seroconversion; Vaccines; Children; Infection; Medical personnel; Infants; Pregnancy; Disabilities; Intervention; Sexually transmitted diseases; Cytomegalovirus DO - http://dx.doi.org/10.1002/rmv.659 ER - TY - JOUR T1 - Eleven years of occupational mortality in law enforcement: The census of fatal occupational injuries, 1992-2002 AN - 1017967132; 16691641 AB - Background Occupational injury deaths remain high for Law Enforcement Officers (LEOs). This study describes and compares intentional and transportation-related fatality rates in US LEOs between 1992 and 2002. Methods Workplace injury deaths among LEOs from 1992 to 2002 were categorized into 'Intentional,' 'Transportation-related,' and 'Other,' using the Census of Fatal Occupational Injuries. Occupations included in this analysis were sheriffs and bailiffs, police and detectives, non-public service guards, and correctional officers. Fatality rates were compared among law enforcement occupations, cause of death, and demographics with rate ratios and 95% confidence intervals. Results During the 11-year period, 2,280 workers died from an occupational injury, for a fatality rate of 11.8 per 100,000 across all LEO occupations. Forty-seven percent were homicides (n=1,072, rate 5.6 per 100,000), 36% transportation-related (n=815, rate 4.2 per 100,000), 11% were due to other causes (n=249, rate 1.3 per 100,000), and 5% were workplace suicides (n=122, rate 0.6 per 100,000). The proportion of fatalities by cause of death differed significantly between occupations (P<0.0001). Sheriffs and bailiffs experience a high risk for occupational injury death compared to other law enforcement occupations. Of the transportation-related fatalities, LEOs were operating a motor-vehicle in 58% of the incidents and 22% of the fatalities were struck by incidents. Conclusions Transportation-related deaths were nearly as common as homicides as a cause of occupational injury death among US LEOs. Struck by vehicle incidents remain an important and overlooked cause of death. This research points to opportunities for the prevention of transportation-related deaths in law enforcement. Am. J. Ind. Med. 53:940-949, 2010. ? 2010 Wiley-Liss, Inc. JF - American Journal of Industrial Medicine AU - Tiesman, Hope M AU - Hendricks, Scott A AU - Bell, Jennifer L AU - Amandus, Harlan A Y1 - 2010/09// PY - 2010 DA - Sep 2010 SP - 940 EP - 949 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 53 IS - 9 SN - 1097-0274, 1097-0274 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Mortality KW - Occupational safety KW - census KW - demography KW - homicide KW - law enforcement KW - police KW - prevention KW - suicide KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1017967132?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Eleven+years+of+occupational+mortality+in+law+enforcement%3A+The+census+of+fatal+occupational+injuries%2C+1992-2002&rft.au=Tiesman%2C+Hope+M%3BHendricks%2C+Scott+A%3BBell%2C+Jennifer+L%3BAmandus%2C+Harlan+A&rft.aulast=Tiesman&rft.aufirst=Hope&rft.date=2010-09-01&rft.volume=53&rft.issue=9&rft.spage=940&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=10970274&rft_id=info:doi/10.1002%2Fajim.20863 L2 - http://onlinelibrary.wiley.com/doi/10.1002/ajim.20863/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2012-06-01 N1 - SubjectsTermNotLitGenreText - demography; census; Mortality; homicide; police; Occupational safety; prevention; law enforcement; suicide DO - http://dx.doi.org/10.1002/ajim.20863 ER - TY - JOUR T1 - Violent Victimization and Perpetration During Adolescence: Developmental Stage Dependent Ecological Models AN - 1008830422; 16467199 AB - Using a variant of the ecological-transactional model and developmental theories of delinquency on a nationally representative sample of adolescents, the current study explored the ecological predictors of violent victimization, perpetration, and both for three different developmental stages during adolescence. We examined the relative influence of individual and family characteristics, peers, and neighborhood characteristics on the odds of experiencing violent victimization and perpetration over time with two waves of the National Longitudinal Study of Adolescent Health for those adolescents who reported no exposure to violence at Wave 1 (N = 8,267; 50% female; 59% Caucasian; 17% African-American; 14% Hispanic). We found that more proximal factors differentiated between different experiences with violence at Wave 2. Also, negative peers significantly differentiated between violent victimization and perpetration, and this influence was strongest in early adolescence. In exploratory analyses, we found that middle adolescents were particularly vulnerable to their disadvantaged neighborhoods for a high-risk group. This analysis is one of the few that considers multiple ecological contexts simultaneously and provides support for developmental differences within adolescence on the influence that peers and neighborhoods have in predicting violent victimization and perpetration. JF - Journal of Youth and Adolescence AU - Matjasko, Jennifer L AU - Needham, Belinda L AU - Grunden, Leslie N AU - Farb, Amy Feldman AD - National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, 4770 Buford Highway NE, MS-F64, Atlanta, GA, 30341, USA, jmatjasko@cdc.gov Y1 - 2010/09// PY - 2010 DA - Sep 2010 SP - 1053 EP - 1066 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 39 IS - 9 SN - 0047-2891, 0047-2891 KW - Risk Abstracts KW - delinquency KW - developmental stages KW - vulnerability KW - victimization KW - Violence KW - Adolescents KW - Ethnic groups KW - longitudinal studies KW - R2 23050:Environment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1008830422?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Youth+and+Adolescence&rft.atitle=Violent+Victimization+and+Perpetration+During+Adolescence%3A+Developmental+Stage+Dependent+Ecological+Models&rft.au=Matjasko%2C+Jennifer+L%3BNeedham%2C+Belinda+L%3BGrunden%2C+Leslie+N%3BFarb%2C+Amy+Feldman&rft.aulast=Matjasko&rft.aufirst=Jennifer&rft.date=2010-09-01&rft.volume=39&rft.issue=9&rft.spage=1053&rft.isbn=&rft.btitle=&rft.title=Journal+of+Youth+and+Adolescence&rft.issn=00472891&rft_id=info:doi/10.1007%2Fs10964-010-9508-7 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - delinquency; vulnerability; developmental stages; victimization; Violence; longitudinal studies; Ethnic groups; Adolescents DO - http://dx.doi.org/10.1007/s10964-010-9508-7 ER - TY - JOUR T1 - Anticounterfeiting Measures Using Portable Raman Spectroscopy AN - 787083550; 13371105 AB - Counterfeiting is a global problem that affects currency, documents, gemstones, clothing, software, pharmaceuticals, electronics, company logs and brands. Raman is an ideal method to verify if a material is real or fake [1,2]. We will describe examples of using a portable Raman spectrometer to authenticate shipping containers, labels and solid oral dosage forms (SODFs). The measurement can be direct (such as measuring an API in a drug) or based on a physical chemical identifiers (PCIDs) that is incorporated within the product (via sprays, coatings, inks/varnishes or hang tags), or as part of the packaging for films, bottles, paper product or blister packs. We will first describe a direct measurement using a portable Raman spectrometer for authenticating artesunate based antimalarial tablets which is a significant problem in third world countries. This spectroscopic method was able to distinguish between genuine (Figure 1) and counterfeit artesunate and to identify the composition of the counterfeit tablets, which contained no measureable levels of artesunate, but consisted mostly of starch, calcite (CaCO(3)), and paracetamol (4-acetamidophenol). JF - XXII International Conference AU - Green, Michael AU - Small, Lyle AU - Ray, Bryan AU - Cox, Rick AD - Center for Disease Control and Prevention, 1600 Clifton Rd. Mailstop F12, Atlanta, GA 30333 USA A2 - Champion, Paul A2 - Ziegler, Lawrence Y1 - 2010/08/13/ PY - 2010 DA - 2010 Aug 13 SP - 728 EP - 729 PB - American Institute of Physics, Ste. 1NO1 2 Huntington Quadrangle Melville NY 11747-4502 USA, [URL:http://proceedings.aip.org/] VL - 1267 SN - 0094-243X, 0094-243X KW - ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Tags KW - Spray KW - Analytical techniques KW - Coating materials KW - Shipping KW - Starch KW - Drugs KW - Q1 08625:Non-edible products KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/787083550?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=XXII+International+Conference&rft.atitle=Anticounterfeiting+Measures+Using+Portable+Raman+Spectroscopy&rft.au=Green%2C+Michael%3BSmall%2C+Lyle%3BRay%2C+Bryan%3BCox%2C+Rick&rft.aulast=Green&rft.aufirst=Michael&rft.date=2010-08-13&rft.volume=1267&rft.issue=&rft.spage=728&rft.isbn=9780735408180&rft.btitle=&rft.title=XXII+International+Conference&rft.issn=0094243X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-04-01 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Tags; Spray; Coating materials; Analytical techniques; Shipping; Starch; Drugs ER - TY - JOUR T1 - Prevalence of Diabetic Retinopathy in the United States, 2005-2008 AN - 877591472; 13650108 AB - CONTEXT: The prevalence of diabetes in the United States has increased. People with diabetes are at risk for diabetic retinopathy. No recent national population-based estimate of the prevalence and severity of diabetic retinopathy exists. OBJECTIVES: To describe the prevalence and risk factors of diabetic retinopathy among US adults with diabetes aged 40 years and older. Design, Setting, and Participants Analysis of a cross-sectional, nationally representative sample of the National Health and Nutrition Examination Survey 2005-2008 (N = 1006). Diabetes was defined as a self-report of a previous diagnosis of the disease (excluding gestational diabetes mellitus) or glycated hemoglobin A1c of 6.5% or greater. Two fundus photographs were taken of each eye with a digital nonmydriatic camera and were graded using the Airlie House classification scheme and the Early Treatment Diabetic Retinopathy Study severity scale. Prevalence estimates were weighted to represent the civilian, noninstitutionalized US population aged 40 years and older. MAIN OUTCOME MEASURE:ments Diabetic retinopathy and vision-threatening diabetic retinopathy. RESULTS: The estimated prevalence of diabetic retinopathy and vision-threatening diabetic retinopathy was 28.5% (95% confidence interval [CI], 24.9%-32.5%) and 4.4% (95% CI, 3.5%-5.7%) among US adults with diabetes, respectively. Diabetic retinopathy was slightly more prevalent among men than women with diabetes (31.6%; 95% CI, 26.8%-36.8%; vs 25.7%; 95% CI, 21.7%-30.1%; P = .04). Non-Hispanic black individuals had a higher crude prevalence than non-Hispanic white individuals of diabetic retinopathy (38.8%; 95% CI, 31.9%-46.1%; vs 26.4%; 95% CI, 21.4%-32.2%; P = .01) and vision-threatening diabetic retinopathy (9.3%; 95% CI, 5.9%-14.4%; vs 3.2%; 95% CI, 2.0%-5.1%; P = .01). Male sex was independently associated with the presence of diabetic retinopathy (odds ratio [OR], 2.07; 95% CI, 1.39-3.10), as well as higher hemoglobin A1c level (OR, 1.45; 95% CI, 1.20-1.75), longer duration of diabetes (OR, 1.06 per year duration; 95% CI, 1.03-1.10), insulin use (OR, 3.23; 95% CI, 1.99-5.26), and higher systolic blood pressure (OR, 1.03 per mm Hg; 95% CI, 1.02-1.03). CONCLUSION: In a nationally representative sample of US adults with diabetes aged 40 years and older, the prevalence of diabetic retinopathy and vision-threatening diabetic retinopathy was high, especially among Non-Hispanic black individuals. JF - JAMA: Journal of the American Medical Association AU - Zhang, Xinzhi AU - Saaddine, Jinan B AU - Chou, Chiu-Fang AU - Cotch, Mary Frances AU - Cheng, Yiling J AU - Geiss, Linda S AU - Gregg, Edward W AU - Albright, Ann L AU - Klein, Barbara EK AU - Klein, Ronald AD - Author Affiliations: Division of Diabetes Translation, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia (Drs Zhang, Saaddine, Chou, Cheng, Geiss, Gregg, and Albright) Y1 - 2010/08/11/ PY - 2010 DA - 2010 Aug 11 SP - 649 EP - 656 PB - American Medical Association, 515 N. State St. Chicago IL 60610 USA VL - 304 IS - 6 SN - 0098-7484, 0098-7484 KW - Risk Abstracts; CSA Neurosciences Abstracts KW - Housing KW - Eye KW - Nutrition KW - Blood pressure KW - Insulin KW - Hemoglobin KW - diabetes mellitus KW - Classification KW - Retinopathy KW - Risk factors KW - Sex KW - Houses KW - blood pressure KW - insulin KW - Diabetes mellitus KW - USA KW - classification KW - Cameras KW - Residential areas KW - R2 23060:Medical and environmental health KW - N3 11027:Neurology & neuropathology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/877591472?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=JAMA%3A+Journal+of+the+American+Medical+Association&rft.atitle=Prevalence+of+Diabetic+Retinopathy+in+the+United+States%2C+2005-2008&rft.au=Zhang%2C+Xinzhi%3BSaaddine%2C+Jinan+B%3BChou%2C+Chiu-Fang%3BCotch%2C+Mary+Frances%3BCheng%2C+Yiling+J%3BGeiss%2C+Linda+S%3BGregg%2C+Edward+W%3BAlbright%2C+Ann+L%3BKlein%2C+Barbara+EK%3BKlein%2C+Ronald&rft.aulast=Zhang&rft.aufirst=Xinzhi&rft.date=2010-08-11&rft.volume=304&rft.issue=6&rft.spage=649&rft.isbn=&rft.btitle=&rft.title=JAMA%3A+Journal+of+the+American+Medical+Association&rft.issn=00987484&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-10-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Hemoglobin; Diabetes mellitus; Houses; Eye; Classification; Risk factors; Retinopathy; Cameras; Nutrition; Insulin; Blood pressure; Sex; diabetes mellitus; Housing; blood pressure; insulin; classification; Residential areas; USA ER - TY - JOUR T1 - Field triage: optimising injury outcomes through use of a revised on-scene decision-making protocol AN - 877592166; 13649696 JF - Injury Prevention AU - Kapil, Vikas AU - Sattin, Richard W AU - Sasser, Scott AU - McGuire, Lisa C AU - Hunt, Richard AD - Centers for Disease Control and Prevention, National Center for Injury Prevention and Control, Atlanta, Georgia, USA Y1 - 2010/08// PY - 2010 DA - Aug 2010 SP - 284 EP - 285 PB - B M J Publishing Group, B.M.A. House London WC1H 9JR UK VL - 16 IS - 4 SN - 1353-8047, 1353-8047 KW - Health & Safety Science Abstracts UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/877592166?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Injury+Prevention&rft.atitle=Field+triage%3A+optimising+injury+outcomes+through+use+of+a+revised+on-scene+decision-making+protocol&rft.au=Kapil%2C+Vikas%3BSattin%2C+Richard+W%3BSasser%2C+Scott%3BMcGuire%2C+Lisa+C%3BHunt%2C+Richard&rft.aulast=Kapil&rft.aufirst=Vikas&rft.date=2010-08-01&rft.volume=16&rft.issue=4&rft.spage=284&rft.isbn=&rft.btitle=&rft.title=Injury+Prevention&rft.issn=13538047&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-10-01 N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - Incidence and Total Lifetime Costs of Motor Vehicle-Related Fatal and Nonfatal Injury by Road User Type, United States, 2005 AN - 855710005; 14138481 AB - Objectives: To estimate the costs of motor vehicle-related fatal and nonfatal injuries in the United States in terms of medical care and lost productivity by road user type. Methods: Incidence and cost data for 2005 were derived from several data sources. Unit costs were calculated for medical spending and productivity losses for fatal and nonfatal injuries, and unit costs were multiplied by incidence to yield total costs. Injury incidence and costs are presented by age, sex, and road user type. Results: Motor vehicle-related fatal and nonfatal injury costs exceeded $99 billion. Costs associated with motor vehicle occupant fatal and nonfatal injuries accounted for 71 percent ($70 billion) of all motor vehicle-related costs, followed by costs associated with motorcyclists ($12 billion), pedestrians ($10 billion), and pedalcyclists ($5 billion). Conclusions: The substantial economic and societal costs associated with these injuries and deaths reinforce the need to implement evidence-based, cost-effective strategies. Evidence-based strategies that target increasing seat belt use, increasing child safety seat use, increasing motorcyclist and pedalcyclist helmet use, and decreasing alcohol-impaired driving are available. JF - Traffic Injury Prevention AU - Naumann, Rebecca B AU - Dellinger, Ann M AU - Zaloshnja, Eduard AU - Lawrence, Bruce A AU - Miller, Ted R AD - Motor Vehicle Injury Prevention Team, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia Y1 - 2010/08// PY - 2010 DA - Aug 2010 SP - 353 EP - 360 PB - Taylor & Francis Group Ltd., 2 Park Square Oxford OX14 4RN UK VL - 11 IS - 4 SN - 1538-9588, 1538-9588 KW - Health & Safety Science Abstracts KW - Mortality KW - Alcohol KW - USA KW - traffic KW - Injuries KW - Economics KW - helmets KW - Motorcycles KW - Protective equipment KW - seat belts KW - H 2000:Transportation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/855710005?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Traffic+Injury+Prevention&rft.atitle=Incidence+and+Total+Lifetime+Costs+of+Motor+Vehicle-Related+Fatal+and+Nonfatal+Injury+by+Road+User+Type%2C+United+States%2C+2005&rft.au=Naumann%2C+Rebecca+B%3BDellinger%2C+Ann+M%3BZaloshnja%2C+Eduard%3BLawrence%2C+Bruce+A%3BMiller%2C+Ted+R&rft.aulast=Naumann&rft.aufirst=Rebecca&rft.date=2010-08-01&rft.volume=11&rft.issue=4&rft.spage=353&rft.isbn=&rft.btitle=&rft.title=Traffic+Injury+Prevention&rft.issn=15389588&rft_id=info:doi/10.1080%2F15389588.2010.486429 L2 - http://www.informaworld.com/smpp/content~db=all~content=a926084087~frm=titlelink LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Alcohol; Mortality; traffic; Injuries; helmets; Economics; Motorcycles; Protective equipment; seat belts; USA DO - http://dx.doi.org/10.1080/15389588.2010.486429 ER - TY - JOUR T1 - Bicycle helmet use among children in the United States: The effects of legislation, personal and household factors AN - 817608365; 13944573 AB - Children ages 5-14 years have the highest rate of bicycle-related injuries in the country. Bicycle helmets can prevent head and brain injuries, which represent the most serious type of bicycle-related injury. Objectives: This paper compares children's bicycle helmet use to that estimated from an earlier study, and explores regional differences in helmet use by existing helmet legislation. Methods: This study was a cross-sectional, list-assisted random-digit-dial telephone survey. Interviews were completed by 9,684 respondents during 2001-2003. The subset with at least one child in the household age 5-14 years (2,409 respondents) answered questions about bicycle helmet use for a randomly selected child in their household. Results: Almost half (48%) of the children always wore their helmet, 23% sometimes wore their helmet, and 29% never wore their helmet. Helmet wearing was significantly associated with race, ethnicity, and child age but was not associated with the sex of the child. Other significant predictors of use included household income, household education, census region, and bicycle helmet law status. Statewide laws were more effective than laws covering smaller areas. The proportion of children who always wore a helmet increased from 25% in 1994 to 48% in 2001-2002. Significant increases in helmet use from 20% to 26% were seen among both sexes, younger (5-9 years) and older (10-14 years) children, and in all four regions of the country. Conclusions: While there has been substantial progress in the number of children who always wear their helmets, more than half do not. Further progress will require using a combination of methods that have been shown to successfully promote consistent helmet use. Impact on industry: minimal. JF - Journal of Safety Research AU - Dellinger, Ann M AU - Kresnow, Marcie-Jo AD - Division of Unintentional Injury Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Mailstop F-62, Atlanta, GA 30341, United States Y1 - 2010/08// PY - 2010 DA - Aug 2010 SP - 375 EP - 380 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK VL - 41 IS - 4 SN - 0022-4375, 0022-4375 KW - Health & Safety Science Abstracts KW - census KW - Age KW - Injuries KW - Children KW - bicycles KW - USA KW - households KW - helmets KW - wear KW - Legislation KW - H 2000:Transportation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/817608365?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Safety+Research&rft.atitle=Bicycle+helmet+use+among+children+in+the+United+States%3A+The+effects+of+legislation%2C+personal+and+household+factors&rft.au=Dellinger%2C+Ann+M%3BKresnow%2C+Marcie-Jo&rft.aulast=Dellinger&rft.aufirst=Ann&rft.date=2010-08-01&rft.volume=41&rft.issue=4&rft.spage=375&rft.isbn=&rft.btitle=&rft.title=Journal+of+Safety+Research&rft.issn=00224375&rft_id=info:doi/10.1016%2Fj.jsr.2010.05.003 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-12-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - census; bicycles; Age; households; Injuries; helmets; Children; wear; Legislation; USA DO - http://dx.doi.org/10.1016/j.jsr.2010.05.003 ER - TY - JOUR T1 - Preliminary assessment of a model to predict mold contamination based on microbial volatile organic compound profiles AN - 760151748; 13147709 AB - Identification of mold growth based on microbial volatile organic compounds (MVOCs) may be a viable alternative to current bioaerosol assessment methodologies. A feed-forward back propagation (FFBP) artificial neural network (ANN) was developed to correlate MVOCs with bioaerosol levels in built environments. A cross-validation MATLAB script was developed to train the ANN and produce model results. Entech Bottle-Vacs were used to collect chemical grab samples at 10 locations in northern NY during 17 sampling periods from July 2006 to August 2007. Bioaerosol samples were collected concurrently with chemical samples. An Anderson N6 impactor was used in conjunction with malt extract agar and dichloran glycerol 18 to collect viable mold samples. Non-viable samples were collected with Air-O-Cell cassettes. Chemical samples and bioaerosol samples were used as model inputs and model targets, respectively. Previous researchers have suggested the use of MVOCs as indicators of mold growth without the use of a pattern recognition program limiting their success. The current proposed strategy implements a pattern recognition program making it instrumental for field applications. This paper demonstrates that FFBP ANN may be used in conjunction with chemical sampling in built environments to predict the presence of mold growth. JF - Science of the Total Environment AU - LeBouf, Ryan F AU - Schuckers, Stephanie A AU - Rossner, Alan AD - Environmental Science and Engineering, Clarkson University, Potsdam, NY, United States, rlebouf@cdc.gov Y1 - 2010/08/01/ PY - 2010 DA - 2010 Aug 01 SP - 3648 EP - 3653 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 408 IS - 17 SN - 0048-9697, 0048-9697 KW - Water Resources Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology; Risk Abstracts; Environment Abstracts; Pollution Abstracts; Aqualine Abstracts; Toxicology Abstracts KW - Agar KW - Contamination KW - Indicators KW - Airborne microorganisms KW - Molds KW - Models KW - Pattern recognition KW - Assessments KW - neural networks KW - Sampling KW - Artificial intelligence KW - Neural networks KW - Model Studies KW - Glycerol KW - Profiles KW - Microorganisms KW - volatile organic compounds KW - Organic Compounds KW - Volatile organic compounds KW - AQ 00007:Industrial Effluents KW - SW 3050:Ultimate disposal of wastes KW - P 0000:AIR POLLUTION KW - A 01450:Environmental Pollution & Waste Treatment KW - X 24360:Metals KW - R2 23010:General: Models, forecasting KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/760151748?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Science+of+the+Total+Environment&rft.atitle=Preliminary+assessment+of+a+model+to+predict+mold+contamination+based+on+microbial+volatile+organic+compound+profiles&rft.au=LeBouf%2C+Ryan+F%3BSchuckers%2C+Stephanie+A%3BRossner%2C+Alan&rft.aulast=LeBouf&rft.aufirst=Ryan&rft.date=2010-08-01&rft.volume=408&rft.issue=17&rft.spage=3648&rft.isbn=&rft.btitle=&rft.title=Science+of+the+Total+Environment&rft.issn=00489697&rft_id=info:doi/10.1016%2Fj.scitotenv.2010.04.054 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-11-01 N1 - Number of references - 3 N1 - Last updated - 2016-02-29 N1 - SubjectsTermNotLitGenreText - Agar; Pattern recognition; Glycerol; Contamination; Neural networks; volatile organic compounds; Molds; Sampling; Models; Artificial intelligence; Airborne microorganisms; neural networks; Volatile organic compounds; Assessments; Profiles; Indicators; Microorganisms; Organic Compounds; Model Studies DO - http://dx.doi.org/10.1016/j.scitotenv.2010.04.054 ER - TY - JOUR T1 - Years of potential life lost caused by prostate cancer deaths in the United States--Projection from 2004 through 2050 AN - 759310305; 13247729 AB - The purpose of this study is to estimate and project the number of years of potential life lost (YPLL) among males who die of prostate cancer in the United States from 2004 through 2050 and compare the projections by race/ethnicity and age, accounting for demographic changes and population growth. We applied the life expectancy method to estimate YPLL caused by deaths of prostate cancer and all cancers in men by using 1999-2004 national mortality data, 2008 census population demographic projections, and 2004 U.S. life tables. We performed sensitivity analyses by varying death rate and population projections, and examined increase in YPLL from population growth, changes in demographics, and death rates. The number of YPLL caused by prostate cancer deaths was projected to increase by 226.1%, from 291,853 in 2004 to 951,753 in 2050. Hispanics were projected to have the fastest growth in YPLL (977.1% from 2004 to 2050) caused by prostate cancer, followed by non-Hispanic blacks (543.1%), and non-Hispanic others (269.7%). People aged 75 or older was projected to account for 62.0% of YPLL from prostate cancer in 2050 compared with 50.8% in 2004. Of the projected increase in YPLL caused by prostate cancer deaths by 2050, 9.8% were due to changes in demographic composition, 26.8% because of mortality change, and 63.4% because of population growth. YPLL due to prostate cancer deaths are projected to increase dramatically, and become a greater burden in the future. The projections highlight the importance of comprehensive cancer control and research on cancers including prostate cancer and racial/ethnic-specific estimates. JF - Cancer Epidemiology AU - Li, Chunyu AU - Ekwueme, Donatus U AD - Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention (CDC), 4770 Buford Highway, MS: K-55, Atlanta, GA 30341, United States, hsf6@cdc.gov Y1 - 2010/08// PY - 2010 DA - Aug 2010 SP - 368 EP - 372 PB - Elsevier Science Ltd., The Boulevard Kidlington Oxford OX5 1GB UK VL - 34 IS - 4 SN - 1877-7821, 1877-7821 KW - Risk Abstracts; Health & Safety Science Abstracts KW - demography KW - census KW - Mortality KW - life span KW - Cancer KW - USA KW - population growth KW - sensitivity analysis KW - prostate cancer KW - Ethnic groups KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/759310305?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cancer+Epidemiology&rft.atitle=Years+of+potential+life+lost+caused+by+prostate+cancer+deaths+in+the+United+States--Projection+from+2004+through+2050&rft.au=Li%2C+Chunyu%3BEkwueme%2C+Donatus+U&rft.aulast=Li&rft.aufirst=Chunyu&rft.date=2010-08-01&rft.volume=34&rft.issue=4&rft.spage=368&rft.isbn=&rft.btitle=&rft.title=Cancer+Epidemiology&rft.issn=18777821&rft_id=info:doi/10.1016%2Fj.canep.2010.04.015 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-10-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - census; demography; Mortality; sensitivity analysis; population growth; life span; prostate cancer; Ethnic groups; Cancer; USA DO - http://dx.doi.org/10.1016/j.canep.2010.04.015 ER - TY - JOUR T1 - Effects of Source Water Quality on Chlorine Inactivation of Adenovirus, Coxsackievirus, Echovirus, and Murine Norovirus AN - 754537270; 13245697 AB - More information is needed on the disinfection efficacy of chlorine for viruses in source water. In this study, chlorine disinfection efficacy was investigated for USEPA Contaminant Candidate List viruses coxsackievirus B5 (CVB5), echovirus 1 (E1), murine norovirus (MNV), and human adenovirus 2 (HAdV2) in one untreated groundwater source and two partially treated surface waters. Disinfection experiments using pH 7 and 8 source water were carried out in duplicate, using 0.2 and 1 mg/liter free chlorine at 5 and 15C. The efficiency factor Hom (EFH) model was used to calculate disinfectant concentration x contact time (CT) values (mg.min/liter) required to achieve 2-, 3-, and 4-log10 reductions in viral titers. In all water types, chlorine disinfection was most effective for MNV, with 3-log10 CT values at 5C ranging from 0.020 to 0.034. Chlorine disinfection was least effective for CVB5 in all water types, with 3-log10 CT values at 5C ranging from 2.3 to 7.9. Overall, disinfection proceeded faster at 15C and pH 7 for all water types. Inactivation of the study viruses was significantly different between water types, but no single source water had consistently different inactivation rates than another. CT values for CVB5 in one type of source water exceeded the recommended CT values set forth by USEPA's Guidance Manual for Compliance with the Filtration and Disinfection Requirements for Public Water Systems using Surface Water Sources. The results of this study demonstrate that water quality plays a substantial role in the inactivation of viruses and should be considered when developing chlorination plans. JF - Applied and Environmental Microbiology AU - Kahler, Amy M AU - Cromeans, Theresa L AU - Roberts, Jacquelin M AU - Hill, Vincent R AD - Atlanta Research and Education Foundation, Decatur, Georgia, akahler@cdc.gov Y1 - 2010/08// PY - 2010 DA - Aug 2010 SP - 5159 EP - 5164 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 76 IS - 15 SN - 0099-2240, 0099-2240 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Virology & AIDS Abstracts KW - Chlorination KW - Disinfection KW - Adenovirus KW - A 01340:Antibiotics & Antimicrobials KW - V 22340:Antiviral Agents UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754537270?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Effects+of+Source+Water+Quality+on+Chlorine+Inactivation+of+Adenovirus%2C+Coxsackievirus%2C+Echovirus%2C+and+Murine+Norovirus&rft.au=Kahler%2C+Amy+M%3BCromeans%2C+Theresa+L%3BRoberts%2C+Jacquelin+M%3BHill%2C+Vincent+R&rft.aulast=Kahler&rft.aufirst=Amy&rft.date=2010-08-01&rft.volume=76&rft.issue=15&rft.spage=5159&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/10.1128%2FAEM.00869-10 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Disinfection; Adenovirus DO - http://dx.doi.org/10.1128/AEM.00869-10 ER - TY - JOUR T1 - Effects of compound capsule containing bifidobacterium and lactobacillus acidophilus on immunity function of mice AN - 899142500; 15297067 AB - Aim: To observe the immune-regulating effects of the compound capsule containing bifidobacterium and lactobacillus acidophilus on mice. Methods: A total of 192 mice were randomly divided into four groups, and each group was divided into four groups (low dose group, middle dose group, high dose group and control group). In vivo normal mice, the tests were made including the ratio of spleen-thymus/body weight, T lymphocyte proliferation of mouse spleen induced by ConA, the response of delayed hypersenitivity, the amount of hemolytic antibility in serum, antiboty-producing cell assay, phagocytic activity of macrophages and the ability of macrophages for carbon particle clearance and cytotoxicity of NK cells by LDH method. Results: The compound capsule containing bifidobacterium and lactobacillus acidophilus could increase the ability of macrophages for carbon clearance (F = 2.872, P = 0.047), the amount of hemolytic antibility in serum (F = 3.748, P = 0.018) and the activity of NK cells (F = 3.866, P = 0.015) in the high dose group. Compared with the control group, significant differences were observed in the middle and high dose groups in the quantity of antibody-producing cells (F = 65.033, P 0.05). Conclusion: The compound capsule containing bifidobacterium and lactobacillus acidophilus may have enhancing effects on cell immumity, humoral immumity, the macrophage engulfining function and NK cell cytotoxicity in mice, so it has the function of enhancing immunity. JF - Zhengzhou Daxue Xuebao (Yixue Ban) - Journal of Zhengzhou University. Medical sciences AU - Li, L AU - Zhang, X AU - Wang, Q AU - Zhang, Y AU - Wang, H AU - Chen, D AD - Henan Center for Disease Control and Prevention, Zhengzhou 450016, dlslily@163.com Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 635 EP - 637 VL - 45 IS - 4 SN - 1671-6825, 1671-6825 KW - Immunology Abstracts; Microbiology Abstracts B: Bacteriology KW - Macrophages KW - Lactobacillus acidophilus KW - Natural killer cells KW - Spleen KW - Immunity KW - Bifidobacterium KW - Cytotoxicity KW - Carbon KW - Concanavalin A KW - Body weight KW - Hypersensitivity (delayed) KW - Phagocytes KW - Lymphocytes T KW - Cell proliferation KW - J 02410:Animal Diseases KW - F 06925:Hypersensitivity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/899142500?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Zhengzhou+Daxue+Xuebao+%28Yixue+Ban%29+-+Journal+of+Zhengzhou+University.+Medical+sciences&rft.atitle=Effects+of+compound+capsule+containing+bifidobacterium+and+lactobacillus+acidophilus+on+immunity+function+of+mice&rft.au=Li%2C+L%3BZhang%2C+X%3BWang%2C+Q%3BZhang%2C+Y%3BWang%2C+H%3BChen%2C+D&rft.aulast=Li&rft.aufirst=L&rft.date=2010-07-01&rft.volume=45&rft.issue=4&rft.spage=635&rft.isbn=&rft.btitle=&rft.title=Zhengzhou+Daxue+Xuebao+%28Yixue+Ban%29+-+Journal+of+Zhengzhou+University.+Medical+sciences&rft.issn=16716825&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-10-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Macrophages; Cytotoxicity; Concanavalin A; Carbon; Hypersensitivity (delayed); Body weight; Phagocytes; Lymphocytes T; Natural killer cells; Spleen; Immunity; Cell proliferation; Lactobacillus acidophilus; Bifidobacterium ER - TY - JOUR T1 - Risk for cognitive deficit in a population-based sample of U.S. children with autism spectrum disorders: Variation by perinatal health factors AN - 862592545; 201110957 AB - Background From 30% to 60% of children with an autism spectrum disorder (ASD) have an IQ measure that falls in the intellectual disability (ID) range. It is not well studied whether, for children within this ASD subgroup, there is variation in the risk for low IQ based on a child's perinatal risk factors. Objective/Hypotheses We assessed whether preterm delivery and term small-for-gestational-age (tSGA) were associated with various measures of cognitive deficit among children with ASDs. Methods A sample of 1129 singleton children born in 1994 and identified through school and health record review as having an ASD by age 8 years were selected from a U.S. population-based surveillance network. Mean IQ and dichotomous IQ outcomes indicating various levels of ID were examined according to whether a child was preterm (<37 weeks' gestation) or tSGA (term delivery and birth weight <10th percentile for gestational age of a U.S. referent). Results for the total sample and within race-ethnicity/maternal education strata were adjusted for child sex and ASD subtype classification. Results Mean IQ was significantly (p < .05) lower in children delivered preterm (69.5) than term (74.5) and tSGA (69.3) than term appropriate-for gestational age (75.3). In stratified analyses, the preterm-IQ association was significant only among non-Hispanic white (NHW) children with maternal education at birth of high school or less; adjusted mean IQ was 8 points lower among those delivered preterm (65.4) than term (73.8). Term-SGA was associated with a significant 8-point deficit in adjusted mean IQ (75.5 vs. 83.8) in NHW children with maternal education greater than high school and a 6-point deficit that approached significance (68.4 vs. 74.5, pNB=NB0.10) in NHW children with maternal education of high school or less. Non-Hispanic black children in both maternal education groups had significantly lower mean IQs than NHW children with little variation by preterm or tSGA. Conclusions In children with ASDs, the risk for concurrent ID or IQ deficit is associated with both preterm delivery and tSGA; these associations may vary by race-ethnicity and SES. Further studies of ASD-ID co-occurrence and the effectiveness of intervention strategies should consider both perinatal and sociodemographic factors. [Copyright Elsevier Inc.] JF - Disability and Health Journal AU - Schieve, Laura A AU - Baio, Jon AU - Rice, Catherine E AU - Durkin, Maureen AU - Kirby, Russell S AU - Drews-Botsch, Carolyn AU - Miller, Lisa A AU - Nicholas, Joyce S AU - Cunniff, Christopher M AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA Y1 - 2010/07// PY - 2010 DA - July 2010 SP - 202 EP - 212 PB - Elsevier Inc., New York NY VL - 3 IS - 3 SN - 1936-5674, 1936-5674 KW - Autistic disorder KW - Intellectual disability KW - Preterm birth KW - Infant KW - Small for gestational age KW - Perinatal factors KW - High schools KW - Autistic children KW - Children KW - Intelligence quotient KW - Autistic spectrum disorders KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/862592545?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Disability+and+Health+Journal&rft.atitle=Risk+for+cognitive+deficit+in+a+population-based+sample+of+U.S.+children+with+autism+spectrum+disorders%3A+Variation+by+perinatal+health+factors&rft.au=Schieve%2C+Laura+A%3BBaio%2C+Jon%3BRice%2C+Catherine+E%3BDurkin%2C+Maureen%3BKirby%2C+Russell+S%3BDrews-Botsch%2C+Carolyn%3BMiller%2C+Lisa+A%3BNicholas%2C+Joyce+S%3BCunniff%2C+Christopher+M&rft.aulast=Schieve&rft.aufirst=Laura&rft.date=2010-07-01&rft.volume=3&rft.issue=3&rft.spage=202&rft.isbn=&rft.btitle=&rft.title=Disability+and+Health+Journal&rft.issn=19365674&rft_id=info:doi/10.1016%2Fj.dhjo.2009.12.001 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2011-04-18 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Children; Intelligence quotient; Autistic children; Autistic spectrum disorders; High schools; Perinatal factors DO - http://dx.doi.org/10.1016/j.dhjo.2009.12.001 ER - TY - JOUR T1 - Changes in autism spectrum disorder prevalence in 4 areas of the United States AN - 862592235; 201110831 AB - Background We sought to describe autism spectrum disorder (ASD) population characteristics and changes in identified prevalence across 3 time periods. Methods Children with a potential ASD were identified through records abstraction at multiple sources with clinician review based on Diagnostic and Statistical Manual (DSM-IV-TR) criteria. Multisite, population-based data from the Autism and Developmental Disabilities Monitoring (ADDM) Network were analyzed from areas of Arizona (AZ), Georgia (GA), Maryland (MD), and South Carolina (SC). Participants were 8-year-old children (born in 1992, 1994, or 1996) in 2000, 2002, or 2004 (and children born in 1988 residing in metropolitan Atlanta in 1996) who had been evaluated for a variety of developmental concerns at education and/or health sources. Results From 2000 to 2004, the identified prevalence of the ASDs per 1,000 8-year-old children showed significant increases of 38% in GA and 72% in MD and a nonsignificant increase of 26% in AZ. ASD prevalence was relatively stable in SC with a nonsignificant decrease of 17%. Males had a higher identified prevalence of ASD in all years. Increases among racial, ethnic, and cognitive functioning subgroups varied by site and surveillance year. More children were classified with an ASD by community professionals over time, except in AZ. Conclusions There was a trend toward increase in identified ASD prevalence among 8-year-old children who met the surveillance case definition in 3 of the 4 study sites from 2000 to 2004. Some of the observed increases are due to improved ascertainment; however, a true increase in ASD symptoms cannot be ruled out. These data confirm that the prevalence of ASDs is undergoing significant change in some areas of the United States and that ASDs continue to be of urgent public health concern. [Copyright Elsevier Inc.] JF - Disability and Health Journal AU - Rice, Catherine AU - Nicholas, Joyce AU - Baio, Jon AU - Pettygrove, Sydney AU - Lee, Li-Ching AU - Van Naarden Braun, Kim AU - Doernberg, Nancy AU - Cunniff, Chris AU - Newschaffer, Craig AU - Meaney, F John AU - Charles, Jane AU - Washington, Anita AU - King, Lydia AU - Kolotos, Maria AU - Mancilla, Kristen AU - Mervis, Cynthia A AU - Carpenter, Laura AU - Yeargin-Allsopp, Marshalyn AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA Y1 - 2010/07// PY - 2010 DA - July 2010 SP - 186 EP - 201 PB - Elsevier Inc., New York NY VL - 3 IS - 3 SN - 1936-5674, 1936-5674 KW - Autism KW - Autism spectrum Disorders KW - Pervasive developmental disorders KW - Prevalence KW - Epidemiology KW - Symptoms KW - Children KW - Surveillance KW - Public health KW - Autistic spectrum disorders KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/862592235?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Disability+and+Health+Journal&rft.atitle=Changes+in+autism+spectrum+disorder+prevalence+in+4+areas+of+the+United+States&rft.au=Rice%2C+Catherine%3BNicholas%2C+Joyce%3BBaio%2C+Jon%3BPettygrove%2C+Sydney%3BLee%2C+Li-Ching%3BVan+Naarden+Braun%2C+Kim%3BDoernberg%2C+Nancy%3BCunniff%2C+Chris%3BNewschaffer%2C+Craig%3BMeaney%2C+F+John%3BCharles%2C+Jane%3BWashington%2C+Anita%3BKing%2C+Lydia%3BKolotos%2C+Maria%3BMancilla%2C+Kristen%3BMervis%2C+Cynthia+A%3BCarpenter%2C+Laura%3BYeargin-Allsopp%2C+Marshalyn&rft.aulast=Rice&rft.aufirst=Catherine&rft.date=2010-07-01&rft.volume=3&rft.issue=3&rft.spage=186&rft.isbn=&rft.btitle=&rft.title=Disability+and+Health+Journal&rft.issn=19365674&rft_id=info:doi/10.1016%2Fj.dhjo.2009.10.008 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2011-04-18 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Autistic spectrum disorders; Prevalence; Children; Surveillance; Public health; Symptoms DO - http://dx.doi.org/10.1016/j.dhjo.2009.10.008 ER - TY - JOUR T1 - Missed Opportunities to Prevent Perinatal Human Immunodeficiency Virus Transmission in 15 Jurisdictions in the United States During 2005-2008 AN - 831094979; 2010-628706 AB - The objective of this study was to identify factors related to failure to receive recommended interventions for the prevention of mother-to-child HIV transmission among HIV-infected pregnant women in the United States. Using Enhanced Perinatal Surveillance data from 2005 through 2008, we identified characteristics of HIV-infected women (n = 5,391) that increased their odds of missing an opportunity to prevent perinatal HIV transmission. Adjusted odds ratios (aORs) and 95% confidence intervals (95% CIs) were calculated by using backward step-wise logistic regression analyses to determine the relationship between demographic variables and missed opportunities. Of 4,220 HIV-infected pregnant women with complete data, 2,545 (60%) did not receive all of the recommended interventions. Missed opportunities for prevention occurred more often among HIV-infected women aged 25-34 years (aOR = 1.9, 95% CI = 1.4-2.5), and greater than 34 years (aOR = 2.0, 95% CI = 1.5-2.7) compared to those 13-19 years and among injection drug users (aOR = 1.3, CI = 1.0-1.5) compared to women infected with HIV through heterosexual contact. Clinicians can decrease missed opportunities by routinely providing recommended interventions, especially among HIV-infected women who are injection drug users or aged 25 years or older. Adapted from the source document. JF - Women & Health AU - Whitmore, Suzanne K AU - Patel-Larson, Alpa AU - Espinoza, Lorena AU - Ruffo, Nan M AU - Rao, Shubha AD - Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA Y1 - 2010/07// PY - 2010 DA - July 2010 SP - 414 EP - 425 PB - Taylor & Francis, Philadelphia PA VL - 50 IS - 5 SN - 0363-0242, 0363-0242 KW - Health conditions and policy - Diseases and disorders KW - Population groups, population policy, and demographics - Women KW - Population groups, population policy, and demographics - Men KW - Administration of justice - Courts and judicial power KW - HIV infection perinatal HIV prevention pregnancy testing and treatment for HIV KW - United States KW - Heterosexuals KW - Human immunodeficiency virus KW - Women KW - Communicable diseases KW - Surveillance KW - Demographics KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/831094979?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Women+%26+Health&rft.atitle=Missed+Opportunities+to+Prevent+Perinatal+Human+Immunodeficiency+Virus+Transmission+in+15+Jurisdictions+in+the+United+States+During+2005-2008&rft.au=Whitmore%2C+Suzanne+K%3BPatel-Larson%2C+Alpa%3BEspinoza%2C+Lorena%3BRuffo%2C+Nan+M%3BRao%2C+Shubha&rft.aulast=Whitmore&rft.aufirst=Suzanne&rft.date=2010-07-01&rft.volume=50&rft.issue=5&rft.spage=414&rft.isbn=&rft.btitle=&rft.title=Women+%26+Health&rft.issn=03630242&rft_id=info:doi/10.1080%2F03630242.2010.506153 LA - English DB - PAIS Index N1 - Date revised - 2010-11-11 N1 - Last updated - 2016-09-28 N1 - CODEN - WOHEDI N1 - SubjectsTermNotLitGenreText - Human immunodeficiency virus; Women; United States; Communicable diseases; Heterosexuals; Demographics; Surveillance DO - http://dx.doi.org/10.1080/03630242.2010.506153 ER - TY - JOUR T1 - Missed Opportunities to Prevent Perinatal Human Immunodeficiency Virus Transmission in 15 Jurisdictions in the United States During 2005-2008 AN - 815541971; 13898743 AB - The objective of this study was to identify factors related to failure to receive recommended interventions for the prevention of mother-to-child HIV transmission among HIV-infected pregnant women in the United States. Using Enhanced Perinatal Surveillance data from 2005 through 2008, we identified characteristics of HIV-infected women (n = 5,391) that increased their odds of missing an opportunity to prevent perinatal HIV transmission. Adjusted odds ratios (aORs) and 95% confidence intervals (95% CIs) were calculated by using backward step-wise logistic regression analyses to determine the relationship between demographic variables and missed opportunities. Of 4,220 HIV-infected pregnant women with complete data, 2,545 (60%) did not receive all of the recommended interventions. Missed opportunities for prevention occurred more often among HIV-infected women aged 25-34 years (aOR = 1.9, 95% CI = 1.4-2.5), and greater than 34 years (aOR = 2.0, 95% CI = 1.5-2.7) compared to those 13-19 years and among injection drug users (aOR = 1.3, CI = 1.0-1.5) compared to women infected with HIV through heterosexual contact. Clinicians can decrease missed opportunities by routinely providing recommended interventions, especially among HIV-infected women who are injection drug users or aged 25 years or older. JF - Women & Health AU - Whitmore, Suzanne K AU - Patel-Larson, Alpa AU - Espinoza, Lorena AU - Ruffo, Nan M AU - Rao, Shubha AD - Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 414 EP - 425 PB - Taylor & Francis Group Ltd., 2 Park Square Oxford OX14 4RN UK VL - 50 IS - 5 SN - 0363-0242, 0363-0242 KW - Immunology Abstracts; Virology & AIDS Abstracts; Health & Safety Science Abstracts KW - demography KW - Data processing KW - disease transmission KW - jurisdiction KW - Drug abuse KW - Disease transmission KW - Pregnancy KW - Demography KW - USA KW - Human immunodeficiency virus KW - intervention KW - prevention KW - Regression analysis KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - V 22360:AIDS and HIV KW - F 06910:Microorganisms & Parasites UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/815541971?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Women+%26+Health&rft.atitle=Missed+Opportunities+to+Prevent+Perinatal+Human+Immunodeficiency+Virus+Transmission+in+15+Jurisdictions+in+the+United+States+During+2005-2008&rft.au=Whitmore%2C+Suzanne+K%3BPatel-Larson%2C+Alpa%3BEspinoza%2C+Lorena%3BRuffo%2C+Nan+M%3BRao%2C+Shubha&rft.aulast=Whitmore&rft.aufirst=Suzanne&rft.date=2010-07-01&rft.volume=50&rft.issue=5&rft.spage=414&rft.isbn=&rft.btitle=&rft.title=Women+%26+Health&rft.issn=03630242&rft_id=info:doi/10.1080%2F03630242.2010.506153 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-11-01 N1 - Number of references - 30 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Demography; Data processing; Regression analysis; Drug abuse; Pregnancy; Disease transmission; demography; disease transmission; Human immunodeficiency virus; intervention; prevention; jurisdiction; USA DO - http://dx.doi.org/10.1080/03630242.2010.506153 ER - TY - JOUR T1 - Parechovirus typing in clinical specimens by nested or semi-nested PCR coupled with sequencing AN - 807255746; 13070030 AB - The Parechovirus genus (Picornaviridae) contains two known species, Human parechovirus (HPeV) and Ljungan virus (LV). HPeVs cause a wide spectrum of disease, including meningitis, gastroenteritis, encephalitis, respiratory illness, and neonatal sepsis-like disease. LVs are associated with diabetes and myocarditis in bank voles and have been proposed to cause disease in humans. The ability to rapidly and accurately type parechoviruses is critical to understanding their role in human disease. For parechovirus molecular typing, we sought to develop reverse transcription, nested polymerase chain reaction (RT-PCR) assays to amplify the sequence encoding the VP1 capsid protein from all known members of the Parechovirus genus. The assays consist of a two-step RT-PCR with primers flanking VP1 (PCR1), followed by semi-nested PCR2A and PCR2B reactions that produce overlapping amplicons, encompassing the complete VP1 gene, as well as a nested PCR2C that amplifies a shorter internal VP1 amplicon. All primer sets are 100% sensitive and 100% specific for the 77 parechovirus culture isolates tested. The semi-nested and nested PCR primer sets are 94% sensitive and 100% specific for detection of parechovirus in original specimens. Viral genotype can be deduced from analysis of amplicon sequences. Parechoviruses of the same type share a[control][yen77% complete VP1 nucleotide sequence identity or a[control][yen87% amino acid identity, while those of different types share a[control][curren]73% nucleotide identity and a[control][curren]81% amino acid identity. The PCR primers described here amplify VP1 sequences from all known parechoviruses, providing a sensitive, reliable system for molecular typing directly from original clinical specimens. JF - Journal of Clinical Virology AU - Nix, WAllan AU - Maher, Kaija AU - Pallansch, Mark A AU - Oberste, MSteven AD - Polio and Picornavirus Laboratory Branch, Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Mailstop G-17, Atlanta, GA 30333, USA, soberste@cdc.gov Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 202 EP - 207 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 48 IS - 3 SN - 1386-6532, 1386-6532 KW - Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts KW - Amino acid sequence KW - Picornaviridae KW - VP1 protein KW - J 02400:Human Diseases KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/807255746?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Virology&rft.atitle=Parechovirus+typing+in+clinical+specimens+by+nested+or+semi-nested+PCR+coupled+with+sequencing&rft.au=Nix%2C+WAllan%3BMaher%2C+Kaija%3BPallansch%2C+Mark+A%3BOberste%2C+MSteven&rft.aulast=Nix&rft.aufirst=WAllan&rft.date=2010-07-01&rft.volume=48&rft.issue=3&rft.spage=202&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Virology&rft.issn=13866532&rft_id=info:doi/10.1016%2Fj.jcv.2010.04.007 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-10-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - VP1 protein; Picornaviridae DO - http://dx.doi.org/10.1016/j.jcv.2010.04.007 ER - TY - JOUR T1 - Public Health in an Era of Personal Health Records: Opportunities for Innovation and New Partnerships AN - 772258380; 201029668 AB - In the near future, citizens will be able to control & manage their own health information through electronic personal health record systems & tools. The clinical benefits of this innovation, such as cost savings, error reduction, & improved communication, have been discussed in the literature & public forums, as have issues related to privacy & confidentiality. Receiving little attention are the benefits these will have for public health. The benefits & potential for innovation are broad & speak directly to core public health functions such as health monitoring, outbreak management, empowerment, linking to services, & research. Coupled with this is a new relationship with citizens as key partners in protecting & promoting the public's health. Adapted from the source document. JF - Journal of Medical Internet Research AU - Bonander, Jason AU - Gates, Suzanne AD - National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA jbonander@cdc.gov Y1 - 2010/07// PY - 2010 DA - July 2010 PB - Gunther Eysenbach MD MPH, Associate Professor, University of Toronto Senior Scientist, Centre for Global eHealth Innovation, Toronto, Canada VL - 12 IS - 3 SN - 1438-8871, 1438-8871 KW - Personal health records KW - public health practice KW - informatics KW - Patient held medical records KW - Innovation KW - Confidentiality KW - Empowerment KW - Health information KW - Public health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/772258380?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Medical+Internet+Research&rft.atitle=Public+Health+in+an+Era+of+Personal+Health+Records%3A+Opportunities+for+Innovation+and+New+Partnerships&rft.au=Bonander%2C+Jason%3BGates%2C+Suzanne&rft.aulast=Bonander&rft.aufirst=Jason&rft.date=2010-07-01&rft.volume=12&rft.issue=3&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Journal+of+Medical+Internet+Research&rft.issn=14388871&rft_id=info:doi/10.2196%2Fjmir.1346 L2 - http://www.jmir.org/ LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2013-05-01 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Public health; Innovation; Patient held medical records; Empowerment; Confidentiality; Health information DO - http://dx.doi.org/10.2196/jmir.1346 ER - TY - JOUR T1 - Geographic and sociodemographic variation in self-reported seat belt use in the United States AN - 760204453; 13201823 AB - With new data available, we sought to update existing literature on the prevalence of self-reported seat belt use by state, region, and rural/urban status and to estimate the strength of the association between seat belt use and rural/urban status adjusted for type of seat belt law and several other factors. We examined data on self-reported use of seat belts from 50 states, the District of Columbia, and three territories using the 2008 Behavioral Risk Factor Surveillance System, a state-based random-digit-dialed telephone survey (n =406,552). Reported seat belt use was assessed by state, U.S. Census regions, and U.S. Department of Agriculture (USDA) rural/urban continuum codes. Overall, 85% of adults in the United States reported they always used seat belts. Regionally, the West had the highest prevalence of persons who reported that they always wear seat belts (89.6%) and the Midwest had the lowest (80.4%). States with primary seat belt laws had the highest prevalence of reported seat belt use, compared with states with secondary or no laws. After adjusting for various sociodemographic characteristics, body mass index, and type of seat belt law, persons in the most densely populated metropolitan areas were significantly more likely to report always wearing seat belts than those in most sparsely populated rural areas (adjusted odds ratio=2.9). Our findings reinforce the evidence that primary enforcement seat belt laws are effective for increasing seat belt use, and suggest that upgrading to primary enforcement laws will be an important strategy for reducing crash-related fatalities in rural areas. JF - Accident Analysis & Prevention AU - Strine, Tara W AU - Beck, Laurie F AU - Bolen, Julie AU - Okoro, Catherine AU - Dhingra, Satvinder AU - Balluz, Lina AD - Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Division of Adult and Community Health, Atlanta, GA, United States Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 1066 EP - 1071 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK VL - 42 IS - 4 SN - 0001-4575, 0001-4575 KW - Health & Safety Science Abstracts KW - Indexing in process UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/760204453?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Accident+Analysis+%26+Prevention&rft.atitle=Geographic+and+sociodemographic+variation+in+self-reported+seat+belt+use+in+the+United+States&rft.au=Strine%2C+Tara+W%3BBeck%2C+Laurie+F%3BBolen%2C+Julie%3BOkoro%2C+Catherine%3BDhingra%2C+Satvinder%3BBalluz%2C+Lina&rft.aulast=Strine&rft.aufirst=Tara&rft.date=2010-07-01&rft.volume=42&rft.issue=4&rft.spage=1066&rft.isbn=&rft.btitle=&rft.title=Accident+Analysis+%26+Prevention&rft.issn=00014575&rft_id=info:doi/10.1016%2Fj.aap.2009.12.014 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-10-01 N1 - Last updated - 2015-04-09 DO - http://dx.doi.org/10.1016/j.aap.2009.12.014 ER - TY - JOUR T1 - Fruits and Vegetables Intake and Physical Activity Among Hypertensive Adults in the United States: Behavioral Risk Factor Surveillance System, 2003 and 2007 AN - 754903396; 13552288 AB - Background Consuming enough fruits and vegetables and engaging in regular physical activity are believed to be two important components of several lifestyle modifications for people with hypertension. The purpose of this study was to measure the degree to which US adults with hypertension achieved recommended intakes of fruits and vegetables and engaged in recommended levels of physical activity in 2003 and 2007. Methods Using the Behavioral Risk Factor Surveillance System (BRFSS) data conducted in 2003 and 2007. Methods using the Behaviroal Risk Factor Surveillance System (BRFSS) data conducted in 2003 (N = 264, 178) and 2007 (N = 430,082), we determined the changes in the prevalence of eating .5 servings of fruits and vegetables and of obtaining Healthy People 2010 recommended level of physical activity among adults with hypertension during the period. Results In 2003 and 2007, among individuals with hypertension, age-adjusted prevalences of eating .5 servings of fruits and vegetables were 23.8 and 24.4% (P = 0.394) and meeting a recommended physical activity level were 38.2 and 40.3% (P < 0.001). With 2003 as the reference, odds ratios (95% confidence interval) of eating .5 servings of fruits and vegetables and meeting a recommended physical activity for 2007 were 1.02 (0.97-1.08) and 1.06 (1.01-1.10), respectively, after adjusting for relevant factors. Conclusions Among hypertensives, less than a quarter are eating five or more servings of fruits and vegetables per day, and less than half are meeting recommended physical activity. In 4 years, there was no statistically significant improvement in intake of fruits and vegetables and just a slight, albeit statistically significant, improvement in physical activity among US adults. JF - American Journal of Hypertension AU - Fang, J AU - Keenan, N L AU - Ayala, C AU - Dai, S AU - Valderrama, AL AD - Division for Heart Disease and Stroke Prevention, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA, jfang@cdc.gov Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 762 EP - 766 VL - 23 IS - 7 SN - 0895-7061, 0895-7061 KW - Physical Education Index KW - Adults KW - Exercise KW - PE 120:Sport: Psychology, Sociology & History UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754903396?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Hypertension&rft.atitle=Fruits+and+Vegetables+Intake+and+Physical+Activity+Among+Hypertensive+Adults+in+the+United+States%3A+Behavioral+Risk+Factor+Surveillance+System%2C+2003+and+2007&rft.au=Fang%2C+J%3BKeenan%2C+N+L%3BAyala%2C+C%3BDai%2C+S%3BValderrama%2C+AL&rft.aulast=Fang&rft.aufirst=J&rft.date=2010-07-01&rft.volume=23&rft.issue=7&rft.spage=762&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Hypertension&rft.issn=08957061&rft_id=info:doi/10.1038%2Fajh.2010.46 LA - English DB - Physical Education Index N1 - Date revised - 2010-09-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Exercise DO - http://dx.doi.org/10.1038/ajh.2010.46 ER - TY - JOUR T1 - Infant Morbidity and Mortality Attributable to Prenatal Smoking in the U.S. AN - 754881214; 13405674 AB - Although prenatal smoking continues to decline, it remains one of the most prevalent preventable causes of infant morbidity and mortality in the U.S. Purpose - The aim of this study was to estimate the proportion of preterm deliveries, term low birth weight deliveries, and infant deaths attributable to prenatal smoking. Methods - Associations were estimated for prenatal smoking and preterm deliveries, term low birth weight (<2500 g) deliveries, sudden infant death syndrome (SIDS), and preterm-related deaths among 3,352,756 singleton, live births using the U.S. Linked Birth/Infant Death Data Set, 2002 birth cohort. The 2002 data set is the most recent, in which 49 states used the same standardized smoking-related question on the birth certificate. Logistic regression models estimated ORs of prenatal smoking for each outcome, and the prenatal smoking population attributable fraction was calculated for each outcome. Results - Prenatal smoking (11.5% of all births) was significantly associated with very (AOR=1.5, 95% CI=1.4, 1.6); moderate (AOR=1.4, 95% CI=1.4, 1.4); and late (AOR=1.2, 95% CI=1.2, 1.3) preterm deliveries; term low birth weight deliveries (AOR=2.3, 95% CI=2.3, 2.5); SIDS (AOR=2.7, 95% CI=2.4, 3.0); and preterm-related deaths (AOR=1.5, 95% CI=1.4, 1.6). It was estimated that 5.3%-7.7% of preterm deliveries, 13.1%-19.0% of term low birth weight deliveries, 23.2%-33.6% of SIDS, and 5.0%-7.3% of preterm-related deaths were attributable to prenatal smoking. Assuming prenatal smoking rates continued to decline after 2002, these PAFs would be slightly lower for 2009 (4.4%-6.3% for preterm-related deaths, 20.2%-29.3% for SIDS deaths). Conclusions - Despite recent declines in the prenatal smoking prevalence, prenatal smoking continues to cause a substantial number of infant deaths in the U.S. JF - American Journal of Preventive Medicine AU - Dietz, Patricia M AU - England, Lucinda J AU - Shapiro-Mendoza, Carrie K AU - Tong, van t AU - Farr, Sherry L AU - Callaghan, William M AD - Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, CDC, Atlanta, Georgia, PDietz@cdc.gov Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 45 EP - 52 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 39 IS - 1 SN - 0749-3797, 0749-3797 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Mortality KW - USA KW - Prenatal experience KW - low-birth-weight KW - Standards KW - Morbidity KW - Infants KW - sudden infant death syndrome KW - R2 23060:Medical and environmental health KW - H 12000:Epidemiology and Public Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754881214?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Infant+Morbidity+and+Mortality+Attributable+to+Prenatal+Smoking+in+the+U.S.&rft.au=Dietz%2C+Patricia+M%3BEngland%2C+Lucinda+J%3BShapiro-Mendoza%2C+Carrie+K%3BTong%2C+van+t%3BFarr%2C+Sherry+L%3BCallaghan%2C+William+M&rft.aulast=Dietz&rft.aufirst=Patricia&rft.date=2010-07-01&rft.volume=39&rft.issue=1&rft.spage=45&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2010.03.009 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-09-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Mortality; Prenatal experience; low-birth-weight; Standards; Morbidity; sudden infant death syndrome; Infants; USA DO - http://dx.doi.org/10.1016/j.amepre.2010.03.009 ER - TY - JOUR T1 - Prevalence of self-reported clinically diagnosed sleep apnea according to obesity status in men and women: National Health and Nutrition Examination Survey, 2005-2006 AN - 754876440; 13255258 AB - Objective - To estimate the prevalence of self-reported clinically diagnosed sleep apnea (diagnosed sleep apnea) according to body mass index (BMI, measure of total obesity) and waist circumference (measure of abdominal obesity) in US adults. Methods - Data from a representative sample of 4309 US adults in the National Health and Nutrition Examination Surveys 2005-2006 were analyzed. Log-linear regression analyses with a robust variance estimator were performed to estimate the prevalence ratios (PR) and 95% confidence intervals (CIs). Results - The overall crude and age-adjusted prevalence estimates of diagnosed sleep apnea were 4.7% (95% CI = 4.0%-5.5%) and 4.5% (95% CI = 3.9%-5.2%) in adults. Age-adjusted prevalence in men (6.1%, 95% CI = 5.0%-7.3%) was higher than that in women (3.1%, 95% CI = 2.1%-4.0%; P = 30 kg/m super(2)) (12.1% vs. 3.0% in men, P < 0.01; 7.0% vs. 0.7% in women, P < 0.01) or abdominal obesity (10.9% vs. 1.9% in men, P < 0.01; 4.6% vs. 0.6% in women, P < 0.01) than that for those without total obesity (BMI < 30 kg/m super(2)) or without abdominal obesity. Conclusions - These results from a nationally representative sample suggest that diagnosed sleep apnea is highly prevalent among adults with obesity in the general population, especially among men. JF - Preventive Medicine AU - Li, Chaoyang AU - Ford, Earl S AU - Zhao, Guixiang AU - Croft, Janet B AU - Balluz, Lina S AU - Mokdad, Ali H AD - Behavioral Surveillance Branch, Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA, cli@cdc.gov Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 18 EP - 23 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 51 IS - 1 SN - 0091-7435, 0091-7435 KW - Risk Abstracts KW - body mass KW - obesity KW - males KW - Females KW - Nutrition KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754876440?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Preventive+Medicine&rft.atitle=Prevalence+of+self-reported+clinically+diagnosed+sleep+apnea+according+to+obesity+status+in+men+and+women%3A+National+Health+and+Nutrition+Examination+Survey%2C+2005-2006&rft.au=Li%2C+Chaoyang%3BFord%2C+Earl+S%3BZhao%2C+Guixiang%3BCroft%2C+Janet+B%3BBalluz%2C+Lina+S%3BMokdad%2C+Ali+H&rft.aulast=Li&rft.aufirst=Chaoyang&rft.date=2010-07-01&rft.volume=51&rft.issue=1&rft.spage=18&rft.isbn=&rft.btitle=&rft.title=Preventive+Medicine&rft.issn=00917435&rft_id=info:doi/10.1016%2Fj.ypmed.2010.03.016 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-09-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - body mass; obesity; males; Females; Nutrition DO - http://dx.doi.org/10.1016/j.ypmed.2010.03.016 ER - TY - JOUR T1 - Multicenter Study To Determine Disk Diffusion and Broth Microdilution Criteria for Prediction of High- and Low-Level Mupirocin Resistance in Staphylococcus aureus AN - 754868834; 13209873 AB - Mupirocin susceptibility testing of Staphylococcus aureus has become more important as mupirocin is used more widely to suppress or eliminate S. aureus colonization and prevent subsequent health care- and community-associated infections. The present multicenter study evaluated two susceptibility testing screening methods to detect mupirocin high-level resistance (HLR), broth microdilution (BMD) MICs of 512 kg/ml, and a 6-mm zone diameter for a disk diffusion (DD) test with a 200-kg disk. Initial testing indicated that with Clinical and Laboratory Standards Institute methods for BMD and DD testing, the optimal conditions for the detection of mupirocin HLR were 24 h of incubation and reading of the DD zone diameters with transmitted light. Using the presence or absence of mupA as the QUOTATION_MARKgold standardQUOTATION_MARK for HLR, the sensitivity and specificity of a single-well 256 kg/ml BMD test were 97 and 99%, respectively, and those for the 200-kg disk test were 98 and 99%, respectively. Testing with two disks, 200 kg and 5 kg, was evaluated for its ability to distinguish HLR isolates (MICs 512 kg/ml), low-level-resistant (LLR) isolates (MICs = 8 to 256 kg/ml), and susceptible isolates (MICs 4 kg/ml). Using no zone with both disks as an indication of HLR and no zone with the 5-kg disk plus any zone with the 200-kg disk as LLR, only 3 of the 340 isolates were misclassified, with 3 susceptible isolates being classified as LLR. Use of standardized MIC or disk tests could enable the detection of emerging high- and low-level mupirocin resistance in S. aureus. JF - Journal of Clinical Microbiology AU - Swenson, Jana M AU - Wong, Betty AU - Simor, Andrew E AU - Thomson, Richard B AU - Ferraro, Mary Jane AU - Hardy, Dwight J AU - Hindler, Janet AU - Jorgensen, James AU - Reller, LBarth AU - Traczewski, Maria AD - The Clinical Microbiology Institute, Wilsonville, Oregon 97070, jms1@cdc.gov Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 2469 EP - 2475 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 48 IS - 7 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Colonization KW - Mupirocin KW - Bone mineral density KW - Diffusion KW - Language KW - Staphylococcus aureus KW - Infection KW - Minimum inhibitory concentration KW - Light effects KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754868834?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Multicenter+Study+To+Determine+Disk+Diffusion+and+Broth+Microdilution+Criteria+for+Prediction+of+High-+and+Low-Level+Mupirocin+Resistance+in+Staphylococcus+aureus&rft.au=Swenson%2C+Jana+M%3BWong%2C+Betty%3BSimor%2C+Andrew+E%3BThomson%2C+Richard+B%3BFerraro%2C+Mary+Jane%3BHardy%2C+Dwight+J%3BHindler%2C+Janet%3BJorgensen%2C+James%3BReller%2C+LBarth%3BTraczewski%2C+Maria&rft.aulast=Swenson&rft.aufirst=Jana&rft.date=2010-07-01&rft.volume=48&rft.issue=7&rft.spage=2469&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.00340-10 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2013-07-15 N1 - SubjectsTermNotLitGenreText - Colonization; Bone mineral density; Mupirocin; Language; Diffusion; Infection; Minimum inhibitory concentration; Light effects; Staphylococcus aureus DO - http://dx.doi.org/10.1128/JCM.00340-10 ER - TY - JOUR T1 - Presence of Coxiella burnetii DNA in the Environment of the United States, 2006 to 2008 AN - 754868713; 13209749 AB - Coxiella burnetii is an obligate intracellular bacterium that causes the zoonotic disease Q fever. Because C. burnetii is highly infectious, can survive under a variety of environmental conditions, and has been weaponized in the past, it is classified as a select agent and is considered a potential bioweapon. The agent is known to be present in domestic livestock and in wild animal populations, but the background levels of C. burnetii in the environment have not been reported. To better understand the amount of C. burnetii present in the environment of the United States, more than 1,600 environmental samples were collected from six geographically diverse parts of the United States in the years 2006 to 2008. DNA was purified from these samples, and the presence of C. burnetii DNA was evaluated by quantitative PCR of the IS1111 repetitive element. Overall, 23.8% of the samples were positive for C. burnetii DNA. The prevalence in the different states ranged from 6 to 44%. C. burnetii DNA was detected in locations with livestock and also in locations with primarily human activity (post offices, stores, schools, etc.). This study demonstrates that C. burnetii is fairly common in the environment in the United States, and any analysis of C. burnetii after a suspected intentional release should be interpreted in light of these background levels. It also suggests that human exposure to C. burnetii may be more common than what is suggested by the number of reported cases of Q fever. JF - Applied and Environmental Microbiology AU - Kersh, Gilbert J AU - Wolfe, Teresa M AU - Fitzpatrick, Kelly A AU - Candee, Amanda J AU - Oliver, Lindsay D AU - Patterson, Nicole E AU - Self, Joshua S AU - Priestley, Rachael A AU - Loftis, Amanda D AU - Massung, Robert F AD - Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, rfm2@cdc.gov Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 4469 EP - 4475 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 76 IS - 13 SN - 0099-2240, 0099-2240 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Biochemistry Abstracts 2: Nucleic Acids; Microbiology Abstracts B: Bacteriology KW - Coxiella burnetii KW - Background levels KW - A 01340:Antibiotics & Antimicrobials KW - J 02400:Human Diseases KW - N 14845:Miscellaneous UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754868713?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Presence+of+Coxiella+burnetii+DNA+in+the+Environment+of+the+United+States%2C+2006+to+2008&rft.au=Kersh%2C+Gilbert+J%3BWolfe%2C+Teresa+M%3BFitzpatrick%2C+Kelly+A%3BCandee%2C+Amanda+J%3BOliver%2C+Lindsay+D%3BPatterson%2C+Nicole+E%3BSelf%2C+Joshua+S%3BPriestley%2C+Rachael+A%3BLoftis%2C+Amanda+D%3BMassung%2C+Robert+F&rft.aulast=Kersh&rft.aufirst=Gilbert&rft.date=2010-07-01&rft.volume=76&rft.issue=13&rft.spage=4469&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/10.1128%2FAEM.00042-10 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Background levels; Coxiella burnetii DO - http://dx.doi.org/10.1128/AEM.00042-10 ER - TY - JOUR T1 - Practical Method for Extraction of PCR-Quality DNA from Environmental Soil Samples AN - 754868693; 13209793 AB - Methods for the extraction of PCR-quality DNA from environmental soil samples by using pairs of commercially available kits were evaluated. Coxiella burnetii DNA was detected in spiked soil samples at <1,000 genome equivalents per gram of soil and in 12 (16.4%) of 73 environmental soil samples. JF - Applied and Environmental Microbiology AU - Fitzpatrick, Kelly A AU - Kersh, Gilbert J AU - Massung, Robert F AD - Rickettsial Zoonoses Branch, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, gkersh@cdc.gov Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 4571 EP - 4573 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 76 IS - 13 SN - 0099-2240, 0099-2240 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Biochemistry Abstracts 2: Nucleic Acids; Microbiology Abstracts B: Bacteriology KW - DNA KW - Soil KW - Coxiella burnetii KW - A 01340:Antibiotics & Antimicrobials KW - N 14810:Methods KW - J 02450:Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754868693?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Practical+Method+for+Extraction+of+PCR-Quality+DNA+from+Environmental+Soil+Samples&rft.au=Fitzpatrick%2C+Kelly+A%3BKersh%2C+Gilbert+J%3BMassung%2C+Robert+F&rft.aulast=Fitzpatrick&rft.aufirst=Kelly&rft.date=2010-07-01&rft.volume=76&rft.issue=13&rft.spage=4571&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/10.1128%2FAEM.02825-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Soil; Coxiella burnetii DO - http://dx.doi.org/10.1128/AEM.02825-09 ER - TY - JOUR T1 - Causes of Outbreaks Associated with Drinking Water in the United States from 1971 to 2006 AN - 754868544; 13206313 AB - Summary: Since 1971, the CDC, EPA, and Council of State and Territorial Epidemiologists (CSTE) have maintained the collaborative national Waterborne Disease and Outbreak Surveillance System (WBDOSS) to document waterborne disease outbreaks (WBDOs) reported by local, state, and territorial health departments. WBDOs were recently reclassified to better characterize water system deficiencies and risk factors; data were analyzed for trends in outbreak occurrence, etiologies, and deficiencies during 1971 to 2006. A total of 833 WBDOs, 577,991 cases of illness, and 106 deaths were reported during 1971 to 2006. Trends of public health significance include (i) a decrease in the number of reported outbreaks over time and in the annual proportion of outbreaks reported in public water systems, (ii) an increase in the annual proportion of outbreaks reported in individual water systems and in the proportion of outbreaks associated with premise plumbing deficiencies in public water systems, (iii) no change in the annual proportion of outbreaks associated with distribution system deficiencies or the use of untreated and improperly treated groundwater in public water systems, and (iv) the increasing importance of Legionella since its inclusion in WBDOSS in 2001. Data from WBDOSS have helped inform public health and regulatory responses. Additional resources for waterborne disease surveillance and outbreak detection are essential to improve our ability to monitor, detect, and prevent waterborne disease in the United States. JF - Clinical Microbiology Reviews AU - Craun, Gunther F AU - Brunkard, Joan M AU - Yoder, Jonathan S AU - Roberts, Virginia A AU - Carpenter, Joe AU - Wade, Tim AU - Calderon, Rebecca L AU - Roberts, Jacquelin M AU - Beach, Michael J AU - Roy, Sharon L AD - Centers for Disease Control and Prevention, Atlanta, Georgia, str2@cdc.gov Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 507 EP - 528 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 23 IS - 3 SN - 0893-8512, 0893-8512 KW - Microbiology Abstracts B: Bacteriology KW - Etiology KW - Data processing KW - Risk factors KW - Ground water KW - Drinking water KW - Legionella KW - Public health KW - J 02310:Genetics & Taxonomy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754868544?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+Microbiology+Reviews&rft.atitle=Causes+of+Outbreaks+Associated+with+Drinking+Water+in+the+United+States+from+1971+to+2006&rft.au=Craun%2C+Gunther+F%3BBrunkard%2C+Joan+M%3BYoder%2C+Jonathan+S%3BRoberts%2C+Virginia+A%3BCarpenter%2C+Joe%3BWade%2C+Tim%3BCalderon%2C+Rebecca+L%3BRoberts%2C+Jacquelin+M%3BBeach%2C+Michael+J%3BRoy%2C+Sharon+L&rft.aulast=Craun&rft.aufirst=Gunther&rft.date=2010-07-01&rft.volume=23&rft.issue=3&rft.spage=507&rft.isbn=&rft.btitle=&rft.title=Clinical+Microbiology+Reviews&rft.issn=08938512&rft_id=info:doi/10.1128%2FCMR.00077-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Etiology; Data processing; Risk factors; Ground water; Drinking water; Public health; Legionella DO - http://dx.doi.org/10.1128/CMR.00077-09 ER - TY - JOUR T1 - Building a Framework for Global Surveillance of the Public Health Implications of Adverse Childhood Experiences AN - 754134876; 201019633 AB - Abstract not available. JF - American Journal of Preventive Medicine AU - Anda, Robert F AU - Butchart, Alexander AU - Felitti, Vincent J AU - Brown, David W AD - Carter Consulting Inc., Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, CDC, Atlanta, Georgia Y1 - 2010/07// PY - 2010 DA - July 2010 SP - 93 EP - 98 PB - Elsevier Science, New York NY VL - 39 IS - 1 SN - 0749-3797, 0749-3797 KW - Childhood experiences KW - Surveillance KW - Public health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754134876?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Building+a+Framework+for+Global+Surveillance+of+the+Public+Health+Implications+of+Adverse+Childhood+Experiences&rft.au=Anda%2C+Robert+F%3BButchart%2C+Alexander%3BFelitti%2C+Vincent+J%3BBrown%2C+David+W&rft.aulast=Anda&rft.aufirst=Robert&rft.date=2010-07-01&rft.volume=39&rft.issue=1&rft.spage=93&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2010.03.015 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-10-21 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Childhood experiences; Public health; Surveillance DO - http://dx.doi.org/10.1016/j.amepre.2010.03.015 ER - TY - JOUR T1 - Reservoir diagnosis of longwall gobs through drawdown tests and decline curve analyses of gob gas venthole productions AN - 753685064; 13259275 AB - Abstract not available. JF - International Journal of Rock Mechanics and Mining Sciences AU - Dougherty, Heather N AU - Karacan, COezgen AU - Goodman, Gerrit VR AD - NIOSH, Pittsburgh Research Laboratory Pittsburgh, PA 15236, USA, igq0@cdc.gov Y1 - 2010/07// PY - 2010 DA - July 2010 SP - 851 EP - 857 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK VL - 47 IS - 5 SN - 1365-1609, 1365-1609 KW - Water Resources Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources KW - Testing Procedures KW - Reservoir KW - Rock Mechanics KW - Drawdown KW - Rock mechanics KW - Mining KW - Reservoirs KW - SW 0810:General KW - Q2 09404:Minerals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/753685064?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Rock+Mechanics+and+Mining+Sciences&rft.atitle=Reservoir+diagnosis+of+longwall+gobs+through+drawdown+tests+and+decline+curve+analyses+of+gob+gas+venthole+productions&rft.au=Dougherty%2C+Heather+N%3BKaracan%2C+COezgen%3BGoodman%2C+Gerrit+VR&rft.aulast=Dougherty&rft.aufirst=Heather&rft.date=2010-07-01&rft.volume=47&rft.issue=5&rft.spage=851&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Rock+Mechanics+and+Mining+Sciences&rft.issn=13651609&rft_id=info:doi/10.1016%2Fj.ijrmms.2010.04.010 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-12-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Reservoir; Rock mechanics; Mining; Testing Procedures; Rock Mechanics; Drawdown; Reservoirs DO - http://dx.doi.org/10.1016/j.ijrmms.2010.04.010 ER - TY - JOUR T1 - Tuberculosis Control: Lessons for Outbreak Preparedness in Correctional Facilities AN - 746163034; 13174685 AB - Correctional facilities typically house large numbers of persons in close and crowded conditions for long periods. Clusters of communicable diseases ranging from simple viral upper respiratory infections to more serious threats, such as tuberculosis (TB), infections with methicillin-resistant Staphylococcus aureus, and influenza, often emerge in these surroundings. The recent H1N1 influenza pandemic highlights the importance of outbreak prevention and containment preparedness, particularly in congregate settings. In this commentary, the authors propose that the TB control model can provide valuable lessons for infection control practitioners to prepare for, identify, investigate, and control outbreaks of communicable diseases to prevent transmission in correctional facilities and to the surrounding community. JF - Journal of Correctional Health Care AU - Parvez, Farah M AU - Lobato, Mark N AU - Greifinger, Robert B AD - Division of Tuberculosis Elimination, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, fparvez@health.nyc.gov Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 239 EP - 242 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU UK VL - 16 IS - 3 SN - 1078-3458, 1078-3458 KW - Microbiology Abstracts B: Bacteriology KW - Influenza KW - Houses KW - pandemics KW - Mycobacterium KW - Drug resistance KW - Tuberculosis KW - Staphylococcus aureus KW - Infection KW - Disease transmission KW - Models KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/746163034?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Correctional+Health+Care&rft.atitle=Tuberculosis+Control%3A+Lessons+for+Outbreak+Preparedness+in+Correctional+Facilities&rft.au=Parvez%2C+Farah+M%3BLobato%2C+Mark+N%3BGreifinger%2C+Robert+B&rft.aulast=Parvez&rft.aufirst=Farah&rft.date=2010-07-01&rft.volume=16&rft.issue=3&rft.spage=239&rft.isbn=&rft.btitle=&rft.title=Journal+of+Correctional+Health+Care&rft.issn=10783458&rft_id=info:doi/10.1177%2F1078345810367593 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-07-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Influenza; pandemics; Houses; Drug resistance; Tuberculosis; Infection; Models; Disease transmission; Mycobacterium; Staphylococcus aureus DO - http://dx.doi.org/10.1177/1078345810367593 ER - TY - JOUR T1 - Are Adolescent Girls With a Physical Disability at Increased Risk for Sexual Violence? AN - 746161868; 13059316 AB - BACKGROUND: The purpose of this study was to investigate whether US female adolescents who self-reported having a physical disability or long-term health problem were more likely to report having been physically forced to have sexual intercourse than US female adolescents without a physical disability or long-term health problem. JF - Journal of School Health AU - Alriksson-Schmidt, Ann I AU - Armour, Brian S AU - Thibadeau, Judy K AD - aHealth Scientist/Senior Service Fellow, (sax3[AT]cdc.gov), Centers for Disease Control and Prevention, National Center on Birth Defects and Developmental Disabilities, Atlanta, GA 30333. Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 361 EP - 367 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 USA VL - 80 IS - 7 SN - 0022-4391, 0022-4391 KW - Risk Abstracts KW - sexual behavior KW - disabilities KW - sexual assault KW - health problems KW - schools KW - Adolescents KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/746161868?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+School+Health&rft.atitle=Are+Adolescent+Girls+With+a+Physical+Disability+at+Increased+Risk+for+Sexual+Violence%3F&rft.au=Alriksson-Schmidt%2C+Ann+I%3BArmour%2C+Brian+S%3BThibadeau%2C+Judy+K&rft.aulast=Alriksson-Schmidt&rft.aufirst=Ann&rft.date=2010-07-01&rft.volume=80&rft.issue=7&rft.spage=361&rft.isbn=&rft.btitle=&rft.title=Journal+of+School+Health&rft.issn=00224391&rft_id=info:doi/10.1111%2Fj.1746-1561.2010.00514.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-07-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - health problems; sexual behavior; schools; disabilities; sexual assault; Adolescents DO - http://dx.doi.org/10.1111/j.1746-1561.2010.00514.x ER - TY - JOUR T1 - A Rapid Antimicrobial Susceptibility Test for Bacillus anthracis AN - 746011813; 13137246 AB - An effective public health response to a deliberate release of Bacillus anthracis will require a rapid distribution of antimicrobial agents for postexposure prophylaxis and treatment. However, conventional antimicrobial susceptibility testing for B. anthracis requires a 16- to 20-h incubation period. To reduce this time, we have combined a modified broth microdilution (BMD) susceptibility testing method with real-time quantitative PCR (qPCR). The growth or inhibition of growth of B. anthracis cells incubated in 2-fold dilutions of ciprofloxacin (CIP) (0.015 to 16 kg/ml) or doxycycline (DOX) (0.06 to 64 kg/ml) was determined by comparing the fluorescence threshold cycle (CT) generated by target amplification from cells incubated with each drug concentration with the CT of the no-drug (positive growth) control. This CT readily differentiated susceptible and nonsusceptible strains. Among susceptible strains, the median CT values were 7.51 cycles for CIP and 7.08 cycles for DOX when drug concentrations were at or above the CLSI breakpoint for susceptibility. For CIP- and DOX-nonsusceptible strains, the CT was <1.0 cycle at the breakpoint for susceptibility. When evaluated with 14 genetically and geographically diverse strains of B. anthracis, the rapid method provided the same susceptibility results as conventional methods but required less than 6 h, significantly decreasing the time required for the selection and distribution of appropriate medical countermeasures. JF - Antimicrobial Agents & Chemotherapy AU - Weigel, Linda M AU - Sue, David AU - Michel, Pierre A AU - Kitchel, Brandon AU - Pillai, Segaran P AD - National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, LWeigel@cdc.gov Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 2793 EP - 2800 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 54 IS - 7 SN - 0066-4804, 0066-4804 KW - Toxicology Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Fluorescence KW - Lymphocytes B KW - Bacillus anthracis KW - Antimicrobial agents KW - Public health KW - Breakpoints KW - Ciprofloxacin KW - Bone mineral density KW - Prophylaxis KW - Polymerase chain reaction KW - Drugs KW - Doxycycline KW - A 01340:Antibiotics & Antimicrobials KW - X 24370:Natural Toxins UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/746011813?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=A+Rapid+Antimicrobial+Susceptibility+Test+for+Bacillus+anthracis&rft.au=Weigel%2C+Linda+M%3BSue%2C+David%3BMichel%2C+Pierre+A%3BKitchel%2C+Brandon%3BPillai%2C+Segaran+P&rft.aulast=Weigel&rft.aufirst=Linda&rft.date=2010-07-01&rft.volume=54&rft.issue=7&rft.spage=2793&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.00247-10 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-07-01 N1 - Number of references - 39 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Ciprofloxacin; Breakpoints; Bone mineral density; Fluorescence; Lymphocytes B; Prophylaxis; Polymerase chain reaction; Drugs; Doxycycline; Public health; Antimicrobial agents; Bacillus anthracis DO - http://dx.doi.org/10.1128/AAC.00247-10 ER - TY - JOUR T1 - Detection of Dirofilaria immitis (Nematoda: Filarioidea) by Polymerase Chain Reaction in Aedes albopictus, Anopheles punctipennis, and Anopheles crucians (Diptera: Culicidae) from Georgia, USA AN - 745644540; 13197997 AB - Potential mosquito vectors of Dirofilaria immitis (Leidy) (Nematoda: Filarioidea), the causative agent of dog heartworm in the southeastern region of the United States, were collected with CDC light traps and gravid traps in seven counties in the state of Georgia, USA. The presence of D. immitis in these mosquitoes was detected by polymerase chain reaction using species-specific primers for the D. immitis surface or cuticular antigen, Overall, 1,574 mosquitoes of 13 species in seven genera were collected; 92% of the specimens were Aedes albopictus (Skuse), Aedes vexans (Meigen), or Anopheles punctipennis (Say). Ae. albopictus, An. punctipennis, and Anopheles crucians Wiedemann were positive for D. immitis DNA. Ae. albopictus had the highest maximum likelihood rate of infection (2.30%; 95% confidence interval [CI] = 1.15-4.00%) followed by An. crucians (1.38%: 95% CI = 0.04-6.93%), and An. punctipennis (0.85%: 95% CI 0.03-4.29%). The detection of D. immitis DNA in the heads and thoraxes of Ae. albopictus (0.40%; 95% CI = 0.12-2.02%) indicates that these mosquitoes can support the development of D. immitis to the infective stage 3 larvae. JF - Journal of Medical Entomology AU - Licitra, Beth AU - Chambers, Eric W AU - Kelly, Rosmarie AU - Burkot, Thomas R Y1 - 2010/07// PY - 2010 DA - July 2010 SP - 634 EP - 638 PB - Entomological Society of America, 9301 Annapolis Rd. Lanham MD 20706 USA VL - 47 IS - 4 SN - 0022-2585, 0022-2585 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Entomology Abstracts KW - Dirofilaria immitis KW - Aedes albopictus KW - Georgia KW - Nucleotide sequence KW - Aedes vexans KW - Anopheles punctipennis KW - Hosts KW - Infection KW - Larval development KW - Heads KW - Population genetics KW - Antigens KW - Polymerase chain reaction KW - Anopheles crucians KW - Aquatic insects KW - Nematoda KW - Heart KW - Light traps KW - Vectors KW - USA, Georgia KW - Culicidae KW - Infective stages KW - Filarioidea KW - DNA KW - Primers KW - Diptera KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - Q5 08524:Public health, medicines, dangerous organisms KW - Q1 08305:Genetics and evolution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745644540?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Medical+Entomology&rft.atitle=Detection+of+Dirofilaria+immitis+%28Nematoda%3A+Filarioidea%29+by+Polymerase+Chain+Reaction+in+Aedes+albopictus%2C+Anopheles+punctipennis%2C+and+Anopheles+crucians+%28Diptera%3A+Culicidae%29+from+Georgia%2C+USA&rft.au=Licitra%2C+Beth%3BChambers%2C+Eric+W%3BKelly%2C+Rosmarie%3BBurkot%2C+Thomas+R&rft.aulast=Licitra&rft.aufirst=Beth&rft.date=2010-07-01&rft.volume=47&rft.issue=4&rft.spage=634&rft.isbn=&rft.btitle=&rft.title=Journal+of+Medical+Entomology&rft.issn=00222585&rft_id=info:doi/10.1603%2FME09277 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-07-01 N1 - Last updated - 2016-02-04 N1 - SubjectsTermNotLitGenreText - Population genetics; Antigens; Nucleotide sequence; DNA; Polymerase chain reaction; Hosts; Larval development; Aquatic insects; Heart; Heads; Infective stages; Light traps; Vectors; Primers; Infection; Dirofilaria immitis; Filarioidea; Aedes vexans; Culicidae; Anopheles punctipennis; Anopheles crucians; Diptera; Aedes albopictus; Nematoda; USA, Georgia DO - http://dx.doi.org/10.1603/ME09277 ER - TY - JOUR T1 - Sequence diversity of genes encoding botulinum neurotoxin type F. AN - 733647827; 20511432 AB - Botulism due to type F botulinum neurotoxin (BoNT/F) is rare (<1% of cases), and only a limited number of clostridial strains producing this toxin type have been isolated. As a result, analysis of the diversity of genes encoding BoNT/F has been challenging. In this study, the entire bont/F nucleotide sequences were determined from 33 type F botulinum toxin-producing clostridial strains isolated from environmental sources and botulism outbreak investigations. We examined proteolytic and nonproteolytic Clostridium botulinum type F strains, bivalent strains, including Bf and Af, and Clostridium baratii type F strains. Phylogenetic analysis revealed that the bont/F genes examined formed 7 subtypes (F1 to F7) and that the nucleotide sequence identities of these subtypes differed by up to 25%. The genes from proteolytic (group I) C. botulinum strains formed subtypes F1 through F5, while the genes from nonproteolytic (group II) C. botulinum strains formed subtype F6. Subtype F7 was composed exclusively of bont/F genes from C. baratii strains. The region of the bont/F5 gene encoding the neurotoxin light chain was found to be highly divergent compared to the other subtypes. Although the bont/F5 nucleotide sequences were found to be identical in strains harboring this gene, the gene located directly upstream (ntnh/F) demonstrated sequence variation among representative strains of this subtype. These results demonstrate that extensive nucleotide diversity exists among genes encoding type F neurotoxins from strains with different phylogenetic backgrounds and from various geographical sources. JF - Applied and environmental microbiology AU - Raphael, Brian H AU - Choudoir, Mallory J AU - Lúquez, Carolina AU - Fernández, Rafael AU - Maslanka, Susan E AD - Centers for Disease Control and Prevention, Atlanta, GA 30329, USA. BRaphael@cdc.gov Y1 - 2010/07// PY - 2010 DA - July 2010 SP - 4805 EP - 4812 VL - 76 IS - 14 KW - DNA, Bacterial KW - 0 KW - botulinum toxin type F KW - Botulinum Toxins KW - EC 3.4.24.69 KW - Index Medicus KW - Phylogeny KW - Humans KW - Sequence Homology KW - Disease Outbreaks KW - Sequence Analysis, DNA KW - Genotype KW - Botulism -- microbiology KW - DNA, Bacterial -- chemistry KW - DNA, Bacterial -- genetics KW - Molecular Sequence Data KW - Botulism -- epidemiology KW - Cluster Analysis KW - Environmental Microbiology KW - Clostridium -- isolation & purification KW - Polymorphism, Genetic KW - Botulinum Toxins -- genetics KW - Clostridium -- genetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733647827?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+environmental+microbiology&rft.atitle=Sequence+diversity+of+genes+encoding+botulinum+neurotoxin+type+F.&rft.au=Raphael%2C+Brian+H%3BChoudoir%2C+Mallory+J%3BL%C3%BAquez%2C+Carolina%3BFern%C3%A1ndez%2C+Rafael%3BMaslanka%2C+Susan+E&rft.aulast=Raphael&rft.aufirst=Brian&rft.date=2010-07-01&rft.volume=76&rft.issue=14&rft.spage=4805&rft.isbn=&rft.btitle=&rft.title=Applied+and+environmental+microbiology&rft.issn=1098-5336&rft_id=info:doi/10.1128%2FAEM.03109-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-10-06 N1 - Date created - 2010-07-08 N1 - Date revised - 2017-01-13 N1 - Genetic sequence - GU206531; GENBANK; GU206530; GU206533; GU271943; GU206532; GU206535; GU206534; GU299676; GU299675; GU221928; GU221929; GU299674; GU221927 N1 - SuppNotes - Cited By: J Clin Microbiol. 2002 Jun;40(6):2260-2 [12037104] BMC Biol. 2009;7:66 [19804621] J Appl Microbiol. 1998 Jan;84(1):5-17 [15244052] Appl Microbiol. 1967 Nov;15(6):1316-23 [4865980] Appl Microbiol. 1968 May;16(5):732-4 [4872996] Appl Microbiol. 1971 Feb;21(2):295-9 [4927406] Appl Microbiol. 1972 Aug;24(2):165-7 [4561099] Appl Microbiol. 1974 Oct;28(4):722 [4607823] J Clin Microbiol. 1985 Apr;21(4):654-5 [3988908] Rev Argent Microbiol. 1986;18(1):29-31 [3317514] J Clin Microbiol. 1987 Dec;25(12):2334-8 [3323228] Arch Dis Child. 1989 Jun;64(6):871-2 [2673055] J Clin Microbiol. 1991 Nov;29(11):2618-20 [1774272] Appl Environ Microbiol. 1998 Feb;64(2):703-8 [9464411] Curr Microbiol. 1998 Oct;37(4):262-8 [9732534] Curr Microbiol. 1998 Nov;37(5):312-8 [9767710] J Mol Biol. 1999 Sep 3;291(5):1091-104 [10518945] Acta Pathol Microbiol Scand. 1960;48:80 [14423425] Pediatr Neurol. 2005 Mar;32(3):193-6 [15730901] Appl Environ Microbiol. 2005 Mar;71(3):1311-7 [15746333] Appl Environ Microbiol. 2005 Jul;71(7):4137-9 [16000834] J Clin Microbiol. 2005 Aug;43(8):4280-2 [16082001] Infect Immun. 2005 Sep;73(9):5450-7 [16113261] Neurology. 2005 Dec 13;65(11):1694-700 [16344510] J Bacteriol. 2007 Feb;189(3):818-32 [17114256] PLoS One. 2007;2(12):e1271 [18060065] Appl Environ Microbiol. 2008 May;74(9):2778-86 [18326685] Appl Environ Microbiol. 2008 Jul;74(14):4390-7 [18502928] BMC Genomics. 2009;10:115 [19298644] J Clin Microbiol. 2009 Jul;47(7):2349-50 [19420169] J Appl Microbiol. 2009 Aug;107(2):465-73 [19291235] Appl Environ Microbiol. 2009 Oct;75(19):6094-101 [19684172] J Clin Microbiol. 2004 Apr;42(4):1713-5 [15071029] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1128/AEM.03109-09 ER - TY - JOUR T1 - Association Between IL-1A Single Nucleotide Polymorphisms and Chronic Beryllium Disease and Beryllium Sensitization AN - 1028075962; 14690978 AB - Objective: To determine if single nucleotide polymorphisms (SNPs) in interleukin (IL) IL-1 A, IL-1B, IL-1RN, IL-2, IL-9, and IL-9R were associated with chronic beryllium disease (CBD) and beryllium sensitization (BeS). Methods: Forty SNPs in six IL genes were evaluated in 85 individuals with CBD, 61 individuals with BeS, and 730 individuals without BeS or CBD (nonsensitized) using a 5' nuclease polymerase chain reaction assay. Logistic regression was used to evaluate the association between IL SNPs, CBD, and BeS, adjusting for plant-site and HLA-DPB1 super(Glu69) in additive, dominant, and recessive inheritance models. Results: IL-1A-1142, IL-1A-3769, and IL-1A-4697 were significantly associated with CBD in both the additive and dominant models compared to individuals with BeS or the nonsensitized. Conclusions: These results indicate that genetic variations in the IL-1 A gene may play a role in the development of CBD but not BeS. JF - Journal of Occupational and Environmental Medicine AU - McCanlies, E C AU - Yucesoy, B AU - Mnatsakanova, A AU - Sloven, JE AU - Andrew, M AU - Frye, B L AU - Schuler, C R AU - Kreiss, K AU - Weston, A AD - NIOSH, CDC, MS-L4050, 1095 Willowdale Road, Morgantown, WV 26505, USA, eim4@cdc.gov PY - 2010 SP - 680 EP - 684 VL - 52 IS - 7 SN - 1076-2752, 1076-2752 KW - Toxicology Abstracts; Biochemistry Abstracts 2: Nucleic Acids KW - Berylliosis KW - Histocompatibility antigen HLA KW - Heredity KW - Interleukin 2 KW - Interleukin 1 KW - Nuclease KW - Interleukin 9 KW - Single-nucleotide polymorphism KW - Beryllium KW - Regression analysis KW - Interleukin 1 receptors KW - Polymerase chain reaction KW - N 14810:Methods KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1028075962?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Association+Between+IL-1A+Single+Nucleotide+Polymorphisms+and+Chronic+Beryllium+Disease+and+Beryllium+Sensitization&rft.au=McCanlies%2C+E+C%3BYucesoy%2C+B%3BMnatsakanova%2C+A%3BSloven%2C+JE%3BAndrew%2C+M%3BFrye%2C+B+L%3BSchuler%2C+C+R%3BKreiss%2C+K%3BWeston%2C+A&rft.aulast=McCanlies&rft.aufirst=E&rft.date=2010-07-01&rft.volume=52&rft.issue=7&rft.spage=680&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e3181e48ec8 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-07-01 N1 - Last updated - 2016-01-21 N1 - SubjectsTermNotLitGenreText - Histocompatibility antigen HLA; Berylliosis; Interleukin 2; Heredity; Single-nucleotide polymorphism; Beryllium; Interleukin 1; Regression analysis; Polymerase chain reaction; Nuclease; Interleukin 1 receptors; Interleukin 9 DO - http://dx.doi.org/10.1097/JOM.0b013e3181e48ec8 ER - TY - JOUR T1 - Occupational fatalities, injuries, illnesses, and related economic loss in the wholesale and retail trade sector AN - 1017962290; 16691654 AB - Background The wholesale and retail trade (WRT) sector employs over 21 million workers, or nearly 19% of the annual average employment in private industry. The perception is that workers in this sector are generally at low risk of occupational injury and death. These workers, however, are engaged in a wide range of demanding job activities and are exposed to a variety of hazards. Prior to this report, a comprehensive appraisal of the occupational fatal and nonfatal burdens affecting the retail and wholesale sectors was lacking. The focus of this review is to assess the overall occupational safety and health burden in WRT and to identify various subsectors that have high rates of burden from occupational causes. Ultimately, these findings should be useful for targeted intervention efforts. Methods We reviewed Bureau of Labor Statistics (BLS), 2006 fatality, injury, and illness data for the WRT sector and provide comparisons between the WRT sector, its' subsectors, and private industry, which serves as a baseline. The BLS data provide both counts and standardized incidence rates for various exposures, events, and injury types for fatalities, injuries, and illnesses. In an effort to estimate the economic burden of these fatalities, injuries, and illnesses, a focused review of the literature was conducted. Results and Conclusion In 2006, WRT workers experienced 820,500 injuries/illnesses and 581 fatalities. The total case injury/illness rate for the retail sector was 4.9/100 FTE and for the wholesale sector 4.1/100 FTE. The WRT sector represents 15.5% of the private sector work population in 2006, yet accounts for 20.1% of nonfatal injuries and illnesses of the private sector. In 2003, the disparity was only 2% but increased to 3% in 2004 and 2005. Three WRT subsectors had injury/illness rates well above the national average: beer/wine/liquor (8.4/100); building materials/supplies (7.6/100); and grocery-related products (7.0/100). Occupational deaths with the highest rates were found in gasoline stations (9.8/100,000), convenience stores (6.1/100,000), and used car dealers (5.5/100,000). In terms of actual numbers, the category of food and beverage stores had 82 fatalities in 2006. Based on 1993 data, costs, both direct and indirect, in the WRT sector for fatal injuries were estimated to exceed $8.6 billion. The full economic loss to society and the family has not been adequately measured. Overexertion and contact with objects/equipment represent the top two events or exposures leading to injury or illness. Together they account for 57% of the events or exposures for nonfatal WRT injuries and illnesses. This sector is important because it is large and pervasive as a result, even a relatively small increase in injury rates and accompanying days away from work will have significant impact on working families and society. Am. J. Ind. Med. 53:673-685, 2010. ? 2010 Wiley-Liss, Inc. JF - American Journal of Industrial Medicine AU - Anderson, Vern Putz AU - Schulte, Paul A AU - Sestito, John AU - Linn, Herb AU - Nguyen, Long S Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 673 EP - 685 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 53 IS - 7 SN - 1097-0274, 1097-0274 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Economics KW - Gasoline KW - Injuries KW - Mortality KW - Occupational safety KW - Perception KW - Reviews KW - Standards KW - private sector KW - Vitaceae KW - H 1000:Occupational Safety and Health KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1017962290?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Occupational+fatalities%2C+injuries%2C+illnesses%2C+and+related+economic+loss+in+the+wholesale+and+retail+trade+sector&rft.au=Anderson%2C+Vern+Putz%3BSchulte%2C+Paul+A%3BSestito%2C+John%3BLinn%2C+Herb%3BNguyen%2C+Long+S&rft.aulast=Anderson&rft.aufirst=Vern&rft.date=2010-07-01&rft.volume=53&rft.issue=7&rft.spage=673&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=10970274&rft_id=info:doi/10.1002%2Fajim.20813 L2 - http://onlinelibrary.wiley.com/doi/10.1002/ajim.20813/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2012-06-01 N1 - SubjectsTermNotLitGenreText - Mortality; Injuries; Gasoline; Perception; Reviews; Occupational safety; Economics; Standards; private sector; Vitaceae DO - http://dx.doi.org/10.1002/ajim.20813 ER - TY - JOUR T1 - Agricultural tractor overturn deaths: Assessment of trends and risk factors AN - 1017962269; 16691653 AB - Background Tractor overturn deaths have been recognized as a public health concern for decades. Studies have reported on the hazards associated with tractor overturns, but none have reported on trends in tractor overturn fatality rates in the United States (US). Methods Tractor overturn fatality data from the Bureau of Labor Statistics Census of Fatal Occupational Injuries were used in Poisson regression models to: identify risk factors associated with overturn fatalities; examine trends in tractor overturn fatality rates between 1992 and 2007; and assess trends in overturn fatality rates for specific risk factors. Results Characteristics found to be associated with tractor overturn fatality rates were age, type of farm, region, and the victim's relationship to the farm (P<0.0001). Older age groups, crop farms, farms in the Midwest and Northeast, and family workers all had higher fatal tractor overturn risks. Overall, tractor overturn fatality rates declined 28.5% between 1992 and 2007. Significant decreases in tractor overturn fatality rates were found for the Northeast and South regions, hired workers, crop farms, and in every age group except those less than 25 years of age. Conclusions Tractor overturn fatality rates decreased between 1992 and 2007. These decreases were not consistent between different categories of the agricultural workforce or regions of the US. Changes in tractor overturn fatality rates may be partially explained by increases in the prevalence of ROPS on farm tractors in the US. ROPS promotion programs are needed to reduce tractor overturn fatalities, especially among those subpopulations at highest risk. Am. J. Ind. Med. Published 2009 Wiley-Liss, Inc. JF - American Journal of Industrial Medicine AU - Myers, John R AU - Hendricks, Kitty J Y1 - 2010/07// PY - 2010 DA - Jul 2010 SP - 662 EP - 672 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 53 IS - 7 SN - 1097-0274, 1097-0274 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Age KW - Agricultural equipment KW - Crops KW - Mortality KW - Occupational safety KW - Public health KW - Risk factors KW - census KW - farms KW - USA KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1017962269?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.atitle=Agricultural+tractor+overturn+deaths%3A+Assessment+of+trends+and+risk+factors&rft.au=Myers%2C+John+R%3BHendricks%2C+Kitty+J&rft.aulast=Myers&rft.aufirst=John&rft.date=2010-07-01&rft.volume=53&rft.issue=7&rft.spage=662&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Industrial+Medicine&rft.issn=10970274&rft_id=info:doi/10.1002%2Fajim.20775 L2 - http://onlinelibrary.wiley.com/doi/10.1002/ajim.20775/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2012-06-01 N1 - SubjectsTermNotLitGenreText - census; Mortality; Age; Risk factors; farms; Occupational safety; Crops; Public health; Agricultural equipment; USA DO - http://dx.doi.org/10.1002/ajim.20775 ER - TY - JOUR T1 - Physical activity and optimal self-rated health of adults with and without diabetes AN - 754552629; 13317450 AB - Regular physical activity can improve people's overall health and contribute to both primary and secondary prevention of many chronic diseases and conditions including diabetes. The aim of this study was to examine the association between levels of physical activity and optimal self-rated health (SRH) of U.S. adults with and without diabetes in all 50 states and territories of the Unites States. We estimated the prevalence of optimal SRH by diabetes status of 430,912 adults aged 18 years and older who participated in the 2007 state-based survey of the Behavioral Risk Factor Surveillance System (BRFSS). Prevalence ratios were produced with multivariate Cox regression models using levels of physical activity as a predictor and status of optimal SRH as an outcome variable while controlling for sociodemographic and behavioral health risk factors. The prevalence of reporting optimal SRH was 53.3%, 52.2%, and 86.2% for adults with type 1 diabetes, type 2 diabetes, and without diabetes, respectively. Also in the aforementioned order, adults who reported being active had an increased likelihood of 81%, 32%, and 18% for reporting optimal SRH, when compared with adults who reported being inactive. Regular physical activity of adults, particularly adults with diabetes, is associated with optimal SRH. The findings of this study underscore the importance of advising and motivating adults with diabetes so that physical activity can be integrated into their lifestyle for diabetes care. Additionally, a population-based effort to promote physical activity in communities may benefit adults in general by improving their overall health and well-being. JF - BMC Public Health AU - Tsai, James AU - Ford, Earl S AU - Li, Chaoyang AU - Zhao, Guixiang AU - Balluz, Lina S AD - Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion Centers for Disease Control and Prevention (CDC), Atlanta, GA 30341, USA Y1 - 2010/06/23/ PY - 2010 DA - 2010 Jun 23 SP - 365 PB - BioMed Central Ltd., Middlesex House London W1T 4LB UK VL - 10 KW - Risk Abstracts; Physical Education Index KW - Risk assessment KW - territory KW - Preventive health KW - Promotion KW - Health KW - Chronic diseases KW - Adults KW - Exercise KW - Counseling KW - Diabetes KW - Public health KW - Lifestyle KW - USA KW - diabetes mellitus KW - Risk factors KW - prevention KW - physical activity KW - R2 23060:Medical and environmental health KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754552629?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=BMC+Public+Health&rft.atitle=Physical+activity+and+optimal+self-rated+health+of+adults+with+and+without+diabetes&rft.au=Tsai%2C+James%3BFord%2C+Earl+S%3BLi%2C+Chaoyang%3BZhao%2C+Guixiang%3BBalluz%2C+Lina+S&rft.aulast=Tsai&rft.aufirst=James&rft.date=2010-06-23&rft.volume=10&rft.issue=&rft.spage=365&rft.isbn=&rft.btitle=&rft.title=BMC+Public+Health&rft.issn=1471-2458&rft_id=info:doi/10.1186%2F1471-2458-10-365 LA - English DB - Physical Education Index; ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Preventive health; Promotion; Risk factors; Chronic diseases; Health; Exercise; Adults; Counseling; Lifestyle; Public health; Diabetes; Risk assessment; diabetes mellitus; territory; prevention; physical activity; USA DO - http://dx.doi.org/10.1186/1471-2458-10-365 ER - TY - JOUR T1 - Alcohol-associated injury visits to emergency departments in Pasto, Colombia in 2006 AN - 954621511; 14314140 AB - Abstract not available. JF - International Journal of Injury Control and Safety Promotion AU - Espitia-Hardeman, Victoria AU - Hungerford, Dan AU - Hill, Holly A AU - Betancourt, Carmen E AU - Villareal, Alba N AU - Caycedo, Luz D AU - Portillo, Carlos AD - Division of Violence Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA, USA Y1 - 2010/06// PY - 2010 DA - Jun 2010 SP - 129 EP - 133 PB - Taylor & Francis Group Ltd., 2 Park Square Oxford OX14 4RN UK VL - 17 IS - 2 SN - 1745-7300, 1745-7300 KW - Health & Safety Science Abstracts KW - Injuries KW - Colombia KW - emergency medical services KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/954621511?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Injury+Control+and+Safety+Promotion&rft.atitle=Alcohol-associated+injury+visits+to+emergency+departments+in+Pasto%2C+Colombia+in+2006&rft.au=Espitia-Hardeman%2C+Victoria%3BHungerford%2C+Dan%3BHill%2C+Holly+A%3BBetancourt%2C+Carmen+E%3BVillareal%2C+Alba+N%3BCaycedo%2C+Luz+D%3BPortillo%2C+Carlos&rft.aulast=Espitia-Hardeman&rft.aufirst=Victoria&rft.date=2010-06-01&rft.volume=17&rft.issue=2&rft.spage=129&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Injury+Control+and+Safety+Promotion&rft.issn=17457300&rft_id=info:doi/10.1080%2F17457301003728544 L2 - http://www.informaworld.com/smpp/content~db=all~content=a920460717~frm=titlelink LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-03-01 N1 - Last updated - 2012-03-30 N1 - SubjectsTermNotLitGenreText - Injuries; emergency medical services; Colombia DO - http://dx.doi.org/10.1080/17457301003728544 ER - TY - JOUR T1 - Utility of high-performance liquid chromatography analysis of mycolic acids and partial 16S rRNA gene sequencing for routine identification of Mycobacterium spp. in a national reference laboratory AN - 807259417; 13198786 AB - High-performance liquid chromatography analysis of mycolic acids and partial gene sequencing for the first 500-bp 5a super(2) end of the 16S rRNA gene were used singularly and in combination to evaluate the final identification of species. Examination of 200 cultures revealed 100 strains of slowly growing mycobacteria (SGM), 91 strains of rapidly growing mycobacteria (RGM), and 9 strains of other genera. SGM were discriminated in complexes with both methods for 56 strains, composed primarily of the Mycobacterium spp.: Mycobacterium avium, Mycobacterium terrae, and Mycobacterium simiae-Mycobacterium lentiflavum. For RGM, 73 strains were associated with complexes designated as Mycobacterium abscessus-Mycobacterium chelonae, Mycobacterium fortuitum-Mycobacterium peregrinum, and Mycobacterium mucogenicum-Mycobacterium phocaicum. Consistent identification of all the isolates differentiated to single species within the Mycobacterium genus was not possible with either test method. Sequencing results often distinguished complexes containing fewer species, and combining the results from each method increased the confidence of identifying the correct species. JF - Diagnostic Microbiology and Infectious Disease AU - Toney, Nadege C AU - Toney, Sean R AU - Butler, WRay AD - Division of Tuberculosis Elimination, National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA, ngc6@cdc.gov Y1 - 2010/06// PY - 2010 DA - June 2010 SP - 143 EP - 152 PB - Elsevier Science, Box 882 New York NY 10159 USA VL - 67 IS - 2 SN - 0732-8893, 0732-8893 KW - Biochemistry Abstracts 2: Nucleic Acids; Microbiology Abstracts B: Bacteriology KW - 16S rRNA gene sequencing KW - High-performance liquid chromatography KW - Mycolic acids KW - Mycobacterium avium KW - rRNA 16S KW - Mycobacterium terrae KW - J 02310:Genetics & Taxonomy KW - N 14815:Nucleotide Sequence UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/807259417?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Diagnostic+Microbiology+and+Infectious+Disease&rft.atitle=Utility+of+high-performance+liquid+chromatography+analysis+of+mycolic+acids+and+partial+16S+rRNA+gene+sequencing+for+routine+identification+of+Mycobacterium+spp.+in+a+national+reference+laboratory&rft.au=Toney%2C+Nadege+C%3BToney%2C+Sean+R%3BButler%2C+WRay&rft.aulast=Toney&rft.aufirst=Nadege&rft.date=2010-06-01&rft.volume=67&rft.issue=2&rft.spage=143&rft.isbn=&rft.btitle=&rft.title=Diagnostic+Microbiology+and+Infectious+Disease&rft.issn=07328893&rft_id=info:doi/10.1016%2Fj.diagmicrobio.2010.02.011 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-11-01 N1 - Last updated - 2016-07-07 N1 - SubjectsTermNotLitGenreText - High-performance liquid chromatography; rRNA 16S; Mycolic acids; Mycobacterium avium; Mycobacterium terrae DO - http://dx.doi.org/10.1016/j.diagmicrobio.2010.02.011 ER - TY - JOUR T1 - Don't forget the distributor! The importance of field testing draft educational materials with key gatekeepers before production and dissemination AN - 758109233; 201027959 AB - Objective: This article presents the results of testing draft folic acid educational materials with key gatekeepers, leading to the development of a Spanish-language print advertisement, poster, and radio public service announcement (PSA) aimed at promoting folic acid consumption among 18- to 25-year-old young Latina adults, as well as a Spanish-language print advertisement, poster, brochure, and radio PSA for 26- to 34-year-old Latina mothers. Design: Individual in-person interviews yielded both qualitative and quantitative data. Method: In-person interviews with key gatekeepers who work closely with Spanish-speaking Latinas. Setting: Interviews were conducted in Miami, Florida; Chicago, Illinois; Los Angeles, California; New York, New York; Denver, Colorado; and San Antonio, Texas, USA. Results: Overall, the gatekeepers' ratings of the materials were high. Important concerns that emerged helped guide changes that were made to the materials to ultimately enhance their reach and effectiveness. Conclusion: Testing draft educational materials with key gatekeepers who work closely with Spanish-speaking Latinas before final development and dissemination is a critical component of an educational outreach effort. Incorporating feedback from these professionals can help enhance the quality of the end product; such feedback can also help researchers assess whether and how the materials will be disseminated. Adapted from the source document. JF - Health Education Journal AU - Flores, Alina L AU - Prue, Christine E AU - Panissidi, Paula AD - National Center on Birth Defects and Developmental Disabilities, USA Y1 - 2010/06// PY - 2010 DA - June 2010 SP - 164 EP - 174 PB - Royal Society of Medicine Press Ltd, London UK VL - 69 IS - 2 SN - 0017-8969, 0017-8969 KW - educational materials folic acid gatekeepers neural tube defects Spanish-speaking Latinas KW - Latin American people KW - Posters KW - Educational materials KW - Advertisements KW - Folic acid KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/758109233?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+Education+Journal&rft.atitle=Don%27t+forget+the+distributor%21+The+importance+of+field+testing+draft+educational+materials+with+key+gatekeepers+before+production+and+dissemination&rft.au=Flores%2C+Alina+L%3BPrue%2C+Christine+E%3BPanissidi%2C+Paula&rft.aulast=Flores&rft.aufirst=Alina&rft.date=2010-06-01&rft.volume=69&rft.issue=2&rft.spage=164&rft.isbn=&rft.btitle=&rft.title=Health+Education+Journal&rft.issn=00178969&rft_id=info:doi/10.1177%2F0017896910366787 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-10-21 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Latin American people; Educational materials; Folic acid; Advertisements; Posters DO - http://dx.doi.org/10.1177/0017896910366787 ER - TY - JOUR T1 - Fall arrest characteristics of a scissor lift AN - 754880199; 13398055 AB - Problem - Census of Fatal Occupational Injuries (CFOI) data indicate 306 aerial lift fatalities between 1992-2003. Seventy-eight of these fatalities specifically involved scissor lifts. Members of standards committees have requested that NIOSH conduct research to determine the effects of safety-control practices related to using fall-protection systems for scissor lifts. Method - This research examined the structural and dynamic stability of a scissor lift subjected to fall arrest forces. This was accomplished by conducting drop tests from a scissor lift. Anchorage locations evaluated included manufacturer-supplied anchorage points on the scissor lift platform as well as mid-rail and top-rail locations. Results - Preliminary drop tests determined that a 2400 lb maximum arrest force (MAF) could be generated by dropping 169 lb through a fall height of 36" using Nystron[registered] rope as a lanyard. The scissor lift maintained structural and dynamic stability for all drop tests when fully extended and on an incline. Discussion - Anchoring a fall arrest system to either the mid-rail or top-rail is not a recommended practice by the scissor lift manufacturer. Anchor points are provided on the platform floor of the scissor lift for this purpose. However, our results demonstrate that the mid-rail and top-rail absorb substantial energy from an arrested fall and may have potential as appropriate anchorage points. Impact to Industry - Employers and workers should consider implementing fall arrest systems when using scissor lifts as part of their overall risk mitigation plan for fall injury prevention. JF - Journal of Safety Research AU - Harris, James R AU - Powers, John R AU - Pan, Christopher S AU - Boehler, Brad AD - National Institute for Occupational Safety and Health, Morgantown, WV USA, JHarris@cdc.gov Y1 - 2010/06// PY - 2010 DA - June 2010 SP - 213 EP - 220 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK VL - 41 IS - 3 SN - 0022-4375, 0022-4375 KW - Risk Abstracts; Health & Safety Science Abstracts KW - Scissor lift KW - Aerial lift KW - Fall arrest KW - census KW - Mortality KW - mitigation KW - arrests KW - Injuries KW - Occupational safety KW - prevention KW - committees KW - R2 23060:Medical and environmental health KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754880199?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Safety+Research&rft.atitle=Fall+arrest+characteristics+of+a+scissor+lift&rft.au=Harris%2C+James+R%3BPowers%2C+John+R%3BPan%2C+Christopher+S%3BBoehler%2C+Brad&rft.aulast=Harris&rft.aufirst=James&rft.date=2010-06-01&rft.volume=41&rft.issue=3&rft.spage=213&rft.isbn=&rft.btitle=&rft.title=Journal+of+Safety+Research&rft.issn=00224375&rft_id=info:doi/10.1016%2Fj.jsr.2010.01.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-09-01 N1 - Last updated - 2016-02-18 N1 - SubjectsTermNotLitGenreText - census; Mortality; mitigation; Injuries; arrests; Occupational safety; prevention; committees DO - http://dx.doi.org/10.1016/j.jsr.2010.01.004 ER - TY - JOUR T1 - Effectiveness of a worker-worn electric-field sensor to detect power-line proximity and electrical-contact AN - 754879905; 13398057 AB - Problem - Construction workers suffer the most electrocutions among all industries. Currently, there are no electrical contact warning devices on the market to protect workers. This paper proposes a worker-worn electric-field sensor. As the worker is in proximity to, or in contact with, a live power-circuit, the sensor sets off an audible/visual warning alarm. The sensor also has the potential to wirelessly trip a wireless-capable circuit breaker, and to trigger a wireless transmitter to notify emergency response of an electrical contact. Methods - An experiment was conducted to measure electric-field variation on simulated human-wrists (10 defrosted hog-legs) in various proximities and in electrical-contact to a simulated power-circuit. The purpose of these tests was to determine the feasibility of developing a worker-worn electric-field detection sensor for use in protecting workers from contact with energized electrical conductors. Results - This study observed a significant electric-field-magnitude increase as a hog-leg approaches the live-circuit, and the distinct electric-field-magnitude jump as the leg contacts with the live-circuit. The observation indicates that this sensor can be an effective device to warn the workers of electrical hazards. Additionally, the sensor has the potential to wirelessly trip a wireless-capable circuit-breaker and trigger a wireless transmitter (such as a cell phone) to notify an emergency response. The prompt notification prevents the worker from further injury caused by postponed medical-care. Impact on Industry - Widespread use of this sensor could lower electrocution and electrically related injury rates in the construction industry. JF - Journal of Safety Research AU - Zeng, Shengke AU - Powers, John R AU - Newbraugh, Bradley H AD - Division of Safety Research, National Institute for Occupational Safety and Health, szeng@cdc.gov Y1 - 2010/06// PY - 2010 DA - Jun 2010 SP - 229 EP - 239 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK VL - 41 IS - 3 SN - 0022-4375, 0022-4375 KW - Health & Safety Science Abstracts KW - Feasibility studies KW - cellular telephones KW - Sensors KW - Injuries KW - Emergency preparedness KW - Construction industry KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754879905?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Safety+Research&rft.atitle=Effectiveness+of+a+worker-worn+electric-field+sensor+to+detect+power-line+proximity+and+electrical-contact&rft.au=Zeng%2C+Shengke%3BPowers%2C+John+R%3BNewbraugh%2C+Bradley+H&rft.aulast=Zeng&rft.aufirst=Shengke&rft.date=2010-06-01&rft.volume=41&rft.issue=3&rft.spage=229&rft.isbn=&rft.btitle=&rft.title=Journal+of+Safety+Research&rft.issn=00224375&rft_id=info:doi/10.1016%2Fj.jsr.2010.02.011 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-09-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Feasibility studies; cellular telephones; Injuries; Sensors; Emergency preparedness; Construction industry DO - http://dx.doi.org/10.1016/j.jsr.2010.02.011 ER - TY - JOUR T1 - The Role of a Poison Control Center in Identifying and Limiting an Outbreak of Foodborne Botulism AN - 754869795; 13210859 AB - Many poison control centers partner with public health agencies to handle weekend and after-hours consultations and emergencies. This event describes the effective use of poison control center capabilities in identifying and limiting an outbreak of foodborne botulism. On September 8, 2006, the poison control center received a call regarding a man aged 77 years admitted to a hospital neurology service with dysarthria, dysphagia, and weakness. The poison control center was contacted regarding a concern for botulism. Further information revealed that the patient's wife and a friend had similar symptoms and had eaten together on the previous night. All three sought treatment at different hospitals. The poison control center successfully located the other two patients and provided information regarding the treatment of botulism. In addition, the poison control center notified the on-call local public health official and the CDC for the release of botulinum antitoxin. Public health officials were informed of our concerns for a foodborne outbreak given the common meal. Their investigation determined that the source of botulism was carrot juice. JF - American Journal of Preventive Medicine AU - Brown, Jennifer AU - Sutter, Mark E AU - Algren, DAdam AU - Thomas, Jerry D AU - Ragone, Sean AU - Schier, Joshua G AU - Geller, Robert J AD - Georgia Poison Center, Education Department, CDC, Atlanta, Georgia, jschier@cdc.gov Y1 - 2010/06// PY - 2010 DA - Jun 2010 SP - 675 EP - 678 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 38 IS - 6 SN - 0749-3797, 0749-3797 KW - Microbiology Abstracts B: Bacteriology KW - Antitoxins KW - Poison control centers KW - Clostridium botulinum KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754869795?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=The+Role+of+a+Poison+Control+Center+in+Identifying+and+Limiting+an+Outbreak+of+Foodborne+Botulism&rft.au=Brown%2C+Jennifer%3BSutter%2C+Mark+E%3BAlgren%2C+DAdam%3BThomas%2C+Jerry+D%3BRagone%2C+Sean%3BSchier%2C+Joshua+G%3BGeller%2C+Robert+J&rft.aulast=Brown&rft.aufirst=Jennifer&rft.date=2010-06-01&rft.volume=38&rft.issue=6&rft.spage=675&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2010.02.007 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Poison control centers; Clostridium botulinum DO - http://dx.doi.org/10.1016/j.amepre.2010.02.007 ER - TY - JOUR T1 - Chlamydia Screening and Pelvic Inflammatory Disease: Insights from Exploratory Time-Series Analyses AN - 754869021; 13210855 AB - Screening for chlamydia has been reported to reduce pelvic inflammatory disease (PID) at the individual level. However, information on population-level association (or causality) is scant. Purpose - This study aims to examine the association between chlamydia and gonorrhea screening and PID diagnoses using time-series analyses. Methods - Monthly chlamydia and gonorrhea screening and PID diagnosis rates were extracted for a cohort of 207,695 continuously enrolled privately insured women from January 2001 to December 2006. An autoregressive integrated moving average model was used to examine whether rates of PID diagnoses in a given month were associated with rates of chlamydia and gonorrhea screening in previous months. Results - Monthly screening rates increased from about 300 to almost 700 per 100,000 for chlamydia and from 250 to almost 650 per 100,000 for gonorrhea, whereas PID diagnosis rates declined during the same period (40-20 per 100,000). Increases in screening rates were associated with decreases in PID diagnosis rates 4 months later. On average, a one-unit (or 10%) increase in the growth of chlamydia and gonorrhea screening rates, separately, in the prior fourth month was significantly associated with a 0.36 (or 3.6%, p<0.05) and 0.32 (or 3.2%, p<0.10) decrease in the growth rate of the PID diagnosis rate, respectively. Conclusions - Although analyses such as these cannot prove causality, the results are consistent with the hypothesis that increases in chlamydia and gonorrhea screening coverage can lead to reductions in PID at the population level. A population-level focus offers advantages over individual-level analyses of screening and PID, such as the ability to capture indirect benefits of increased screening. JF - American Journal of Preventive Medicine AU - Owusu-Edusei, Kwame AU - Bohm, Michele K AU - Chesson, Harrell W AU - Kent, Charlotte K AD - Division of STD Prevention, CDC, Atlanta, Georgia, Kowusuedusei@cdc.gov Y1 - 2010/06// PY - 2010 DA - Jun 2010 SP - 652 EP - 657 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 38 IS - 6 SN - 0749-3797, 0749-3797 KW - Microbiology Abstracts B: Bacteriology KW - Gonorrhea KW - Chlamydia KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754869021?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Chlamydia+Screening+and+Pelvic+Inflammatory+Disease%3A+Insights+from+Exploratory+Time-Series+Analyses&rft.au=Owusu-Edusei%2C+Kwame%3BBohm%2C+Michele+K%3BChesson%2C+Harrell+W%3BKent%2C+Charlotte+K&rft.aulast=Owusu-Edusei&rft.aufirst=Kwame&rft.date=2010-06-01&rft.volume=38&rft.issue=6&rft.spage=652&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2010.02.008 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Gonorrhea; Chlamydia DO - http://dx.doi.org/10.1016/j.amepre.2010.02.008 ER - TY - JOUR T1 - In Vitro Antiviral Activity of Favipiravir (T-705) against Drug-Resistant Influenza and 2009 A(H1N1) Viruses AN - 746073684; 12923675 AB - Favipiravir (T-705) has previously been shown to have a potent antiviral effect against influenza virus and some other RNA viruses in both cell culture and in animal models. Currently, favipiravir is undergoing clinical evaluation for the treatment of influenza A and B virus infections. In this study, favipiravir was evaluated in vitro for its ability to inhibit the replication of a representative panel of seasonal influenza viruses, the 2009 A(H1N1) strains, and animal viruses with pandemic (pdm) potential (swine triple reassortants, H2N2, H4N2, avian H7N2, and avian H5N1), including viruses which are resistant to the currently licensed anti-influenza drugs. All viruses were tested in a plaque reduction assay with MDCK cells, and a subset was also tested in both yield reduction and focus inhibition (FI) assays. For the majority of viruses tested, favipiravir significantly inhibited plaque formation at 3.2 kM (0.5 kg/ml) (50% effective concentrations [EC50s] of 0.19 to 22.48 kM and 0.03 to 3.53 kg/ml), and for all viruses, with the exception of a single dually resistant 2009 A(H1N1) virus, complete inhibition of plaque formation was seen at 3.2 kM (0.5 kg/ml). Due to the 2009 pandemic and increased drug resistance in circulating seasonal influenza viruses, there is an urgent need for new drugs which target influenza. This study demonstrates that favipiravir inhibits in vitro replication of a wide range of influenza viruses, including those resistant to currently available drugs. JF - Antimicrobial Agents & Chemotherapy AU - Sleeman, Katrina AU - Mishin, Vasiliy P AU - Deyde, Varough M AU - Furuta, Yousuke AU - Klimov, Alexander I AU - Gubareva, Larisa V AD - Virus Surveillance and Diagnosis Branch, Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, LGubareva@cdc.gov Y1 - 2010/06// PY - 2010 DA - Jun 2010 SP - 2517 EP - 2524 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 54 IS - 6 SN - 0066-4804, 0066-4804 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Virology & AIDS Abstracts KW - Replication KW - Drug resistance KW - Influenza A KW - Animal models KW - RNA viruses KW - Cell culture KW - Infection KW - Antiviral activity KW - pandemics KW - Influenza virus KW - Antiviral agents KW - Plaques KW - A 01340:Antibiotics & Antimicrobials KW - V 22320:Replication UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/746073684?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=In+Vitro+Antiviral+Activity+of+Favipiravir+%28T-705%29+against+Drug-Resistant+Influenza+and+2009+A%28H1N1%29+Viruses&rft.au=Sleeman%2C+Katrina%3BMishin%2C+Vasiliy+P%3BDeyde%2C+Varough+M%3BFuruta%2C+Yousuke%3BKlimov%2C+Alexander+I%3BGubareva%2C+Larisa+V&rft.aulast=Sleeman&rft.aufirst=Katrina&rft.date=2010-06-01&rft.volume=54&rft.issue=6&rft.spage=2517&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.01739-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - pandemics; Antiviral agents; Replication; Influenza A; Drug resistance; Animal models; Cell culture; RNA viruses; Plaques; Antiviral activity; Infection; Influenza virus DO - http://dx.doi.org/10.1128/AAC.01739-09 ER - TY - JOUR T1 - Physical activity levels and differences in the prevalence of diabetes between the United States and Canada AN - 745934966; 13041349 AB - Objective. - To examine the American-Canadian difference in physical activity and its association with diabetes prevalence. Methods. - We used cross-sectional data from nationally representative samples of adults (8688 persons aged >= 18 years) participating in the 2004 Joint Canada/U.S. Survey of Health. Using data on up to 22 activities in the past 3 months, we defined 3 physical activity groups (in metabolic equivalents-hours/day) as low (= 3.0). We employed logistic regression models in our analyses. Results. - Self-reported diabetes prevalence was 7.6% in the U.S. and 5.4% in Canada. The prevalence of low physical activity was considerably higher in the U.S. (70.9%) than in Canada (52.3%), while levels of moderate and high physical activity were higher in Canada (24.6% and 23.1%, respectively) than in the U.S. (14.3% and 14.8%, respectively). Using nationality (Canada as reference) to predict diabetes status, the adjusted odds ratio was 1.48 (95%CI, 1.22-1.79), and became 1.38 (95%CI, 1.15-1.66) when additionally adjusting for physical activity level. We estimate that 20.8% of the U.S.-Canada difference in diabetes prevalence is associated with physical activity. Conclusions. - The difference in the prevalence of diabetes between U.S. and Canadian adults may be partially explained by differences in physical activity between the two countries. JF - Preventive Medicine AU - Zhang, Xuanping AU - Geiss, Linda S AU - Caspersen, Carl J AU - Cheng, Yiling J AU - Engelgau, Michael M AU - Johnson, Jeffrey A AU - Plotnikoff, Ronald C AU - Gregg, Edward W AD - Division of Diabetes Translation, CDC, Atlanta, GA, USA, xbz2@cdc.gov Y1 - 2010/06// PY - 2010 DA - Jun 2010 SP - 241 EP - 245 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 50 IS - 5-6 SN - 0091-7435, 0091-7435 KW - Physical Education Index KW - Objectives KW - Analysis KW - Surveys KW - Health KW - Exercise KW - Adults KW - Activities KW - Diabetes KW - Joints KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745934966?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Preventive+Medicine&rft.atitle=Physical+activity+levels+and+differences+in+the+prevalence+of+diabetes+between+the+United+States+and+Canada&rft.au=Zhang%2C+Xuanping%3BGeiss%2C+Linda+S%3BCaspersen%2C+Carl+J%3BCheng%2C+Yiling+J%3BEngelgau%2C+Michael+M%3BJohnson%2C+Jeffrey+A%3BPlotnikoff%2C+Ronald+C%3BGregg%2C+Edward+W&rft.aulast=Zhang&rft.aufirst=Xuanping&rft.date=2010-06-01&rft.volume=50&rft.issue=5-6&rft.spage=241&rft.isbn=&rft.btitle=&rft.title=Preventive+Medicine&rft.issn=00917435&rft_id=info:doi/10.1016%2Fj.ypmed.2010.02.015 LA - English DB - Physical Education Index N1 - Date revised - 2010-07-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Analysis; Objectives; Surveys; Health; Adults; Exercise; Activities; Joints; Diabetes DO - http://dx.doi.org/10.1016/j.ypmed.2010.02.015 ER - TY - JOUR T1 - Characteristics of pregnant illicit drug users and associations between cannabis use and perinatal outcome in a population-based study AN - 745713366; 13141701 AB - According to the 2004 National Survey on Drug Use and Health, 4.6% of American women reported use of an illicit drug during pregnancy. Previous studies on illicit drug use during pregnancy and perinatal outcomes showed inconsistent results. Methods - This population-based study included mothers who delivered live-born infants without birth defects between 1997 and 2004 and completed interviews for the National Birth Defects Prevention Study (response rate 69%; n = 5871). Prevalence of self-reported illicit drug use (specifically cannabis, cocaine, and stimulants) during pregnancy and its associations with demographic and social factors were assessed. We used multivariable linear and logistic regression analyses to study the associations of cannabis use with birth weight and gestational age. Results - The prevalence of reported illicit drug use during pregnancy was 3.6% (standard error 0.24). Pregnant users of cannabis, cocaine, and stimulants were younger, had a lower level of education and lower household income, and were less likely to have used folic acid in the periconceptional period than nonusers. Illicit drug users were also more likely to have used alcohol and tobacco. After adjustment for confounding, cannabis use was not associated with mean birth weight or gestational age or with low birth weight or preterm delivery. Conclusion - Women who report use of illicit drugs during pregnancy differ in demographic and socioeconomic background from nonusers. Reported cannabis use does not seem to be associated with low birth weight or preterm birth. JF - Drug and Alcohol Dependence AU - Van Gelder, Marleen MHJ AU - Reefhuis, Jennita AU - Caton, Alissa R AU - Werler, Martha M AU - Druschel, Charlotte M AU - Roeleveld, Nel AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Mail-Stop E-86, 1600 Clifton Road, Atlanta, GA 30333, USA, nzr5@cdc.gov Y1 - 2010/06/01/ PY - 2010 DA - 2010 Jun 01 SP - 243 EP - 247 PB - Elsevier Science, P.O. Box 85 Limerick Ireland VL - 109 IS - 1-3 SN - 0376-8716, 0376-8716 KW - Toxicology Abstracts; Health & Safety Science Abstracts KW - Pregnancy KW - Substance abuse KW - Prenatal exposure KW - Birth weight KW - Gestational age KW - demography KW - Age KW - low-birth-weight KW - Socioeconomics KW - Drug abuse KW - Demography KW - households KW - income KW - prevention KW - Tobacco KW - Cannabis KW - Regression analysis KW - birth weight KW - Congenital defects KW - Folic acid KW - Cocaine KW - Drugs KW - Ethanol KW - Alcohol KW - cocaine KW - Population studies KW - Stimulants KW - folic acid KW - Drug dependence KW - Socio-economic aspects KW - Education KW - Infants KW - X 24380:Social Poisons & Drug Abuse KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745713366?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Drug+and+Alcohol+Dependence&rft.atitle=Characteristics+of+pregnant+illicit+drug+users+and+associations+between+cannabis+use+and+perinatal+outcome+in+a+population-based+study&rft.au=Van+Gelder%2C+Marleen+MHJ%3BReefhuis%2C+Jennita%3BCaton%2C+Alissa+R%3BWerler%2C+Martha+M%3BDruschel%2C+Charlotte+M%3BRoeleveld%2C+Nel&rft.aulast=Van+Gelder&rft.aufirst=Marleen&rft.date=2010-06-01&rft.volume=109&rft.issue=1-3&rft.spage=243&rft.isbn=&rft.btitle=&rft.title=Drug+and+Alcohol+Dependence&rft.issn=03768716&rft_id=info:doi/10.1016%2Fj.drugalcdep.2010.01.007 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-07-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Birth weight; Gestational age; Population studies; Stimulants; Drug abuse; Pregnancy; Demography; Socio-economic aspects; Drug dependence; Regression analysis; Cannabis; Tobacco; Congenital defects; Cocaine; Folic acid; Infants; Ethanol; demography; Alcohol; Age; cocaine; low-birth-weight; Socioeconomics; folic acid; households; Education; income; prevention; birth weight; Drugs DO - http://dx.doi.org/10.1016/j.drugalcdep.2010.01.007 ER - TY - JOUR T1 - Birth Defects and Genetic Disorders Among Arab Americans-Michigan, 1992-2003 AN - 742723692; 201014734 AB - Birth defects and genetic disorders are leading causes of infant morbidity and mortality in many countries. Population-based data on birth defects among Arab-American children have not been documented previously. Michigan has the second largest Arab-American community in the United States after California. Using data from the Michigan Birth Defects Registry (MBDR), which includes information on parents' country of birth and ancestry, birth prevalences were estimated in offspring of Michigan women of Arab ancestry for 21 major categories of birth defects and 12 congenital endocrine, metabolic, and hereditary disorders. Compared with other non-Hispanic white children in Michigan, Arab-American children had similar or lower birth prevalences of the selected types of structural birth defects, with higher rates of certain hereditary blood disorders and three categories of metabolic disorders. These estimates are important for planning preconception and antenatal health care, genetic counseling, and clinical care for Arab Americans. Adapted from the source document. JF - Journal of Immigrant and Minority Health AU - Yanni, Emad A AU - Copeland, Glenn AU - Olney, Richard S AD - Centers for Disease Control and Prevention, National Center on Birth Defects and Developmental Disabilities, 1600 Clifton Road, NE, MS E03, Atlanta, GA, 30333, USA eyanni@cdc.gov Y1 - 2010/06// PY - 2010 DA - June 2010 SP - 408 EP - 413 PB - Springer, Dordrecht The Netherlands VL - 12 IS - 3 SN - 1557-1912, 1557-1912 KW - Birth defects KW - Genetics KW - Arabs KW - Metabolic diseases KW - Blood disorders KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742723692?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Immigrant+and+Minority+Health&rft.atitle=Birth+Defects+and+Genetic+Disorders+Among+Arab+Americans-Michigan%2C+1992-2003&rft.au=Yanni%2C+Emad+A%3BCopeland%2C+Glenn%3BOlney%2C+Richard+S&rft.aulast=Yanni&rft.aufirst=Emad&rft.date=2010-06-01&rft.volume=12&rft.issue=3&rft.spage=408&rft.isbn=&rft.btitle=&rft.title=Journal+of+Immigrant+and+Minority+Health&rft.issn=15571912&rft_id=info:doi/10.1007%2Fs10903-008-9203-x LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-10-21 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Birth defects; Arabs; Metabolic diseases; Blood disorders; Genetics DO - http://dx.doi.org/10.1007/s10903-008-9203-x ER - TY - JOUR T1 - Public health partnerships in medical toxicology education and practice. AN - 733558914; 20494245 AB - In December 2002, the medical toxicology sub-board, which consists of representatives from emergency medicine, preventive medicine, and pediatrics, released revised core content for medical toxicology, aiming to better meet the academic challenges imposed by the continually expanding knowledge base of medical toxicology. These challenges included the addition of relatively new areas of interest in medical toxicology, including population health, while simultaneously ensuring that a structural framework existed to accommodate future areas of interest. There is no evidence readily available to assess how well the educational curricula of existing fellowship programs are meeting these needs. In an effort to address this, the authors describe a medical toxicology fellowship program that consists of a partnership among the Emory University School of Medicine, the Georgia Poison Control Center, and the CDC, as well as the results of a reorganization of its academic curriculum that occurred in 2006. To the best of the authors' knowledge, this is the first published report describing such a curriculum redesign. Suggestions and potential resources proposed as enhancements for the public health-associated education of medical toxicology fellows are discussed. The authors also seek to initiate a discussion among programs about how to optimally meet the new challenges developed by the medical toxicology sub-board. Published by Elsevier Inc. JF - American journal of preventive medicine AU - Schier, Joshua G AU - Rubin, Carol AU - Schwartz, Michael D AU - Thomas, Jerry D AU - Geller, Robert J AU - Morgan, Brent W AU - McGeehin, Michael A AU - Frumkin, Howard AD - National Center for Environmental Health, CDC, Atlanta, Georgia 30341, USA. jschier@cdc.gov Y1 - 2010/06// PY - 2010 DA - June 2010 SP - 667 EP - 674 VL - 38 IS - 6 KW - Index Medicus KW - United States KW - Public-Private Sector Partnerships -- organization & administration KW - Specialty Boards KW - Humans KW - Curriculum KW - Georgia KW - Centers for Disease Control and Prevention (U.S.) -- organization & administration KW - Schools, Medical -- organization & administration KW - Fellowships and Scholarships -- organization & administration KW - Education, Medical, Graduate -- organization & administration KW - Poison Control Centers -- organization & administration KW - Toxicology -- education UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733558914?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+journal+of+preventive+medicine&rft.atitle=Public+health+partnerships+in+medical+toxicology+education+and+practice.&rft.au=Schier%2C+Joshua+G%3BRubin%2C+Carol%3BSchwartz%2C+Michael+D%3BThomas%2C+Jerry+D%3BGeller%2C+Robert+J%3BMorgan%2C+Brent+W%3BMcGeehin%2C+Michael+A%3BFrumkin%2C+Howard&rft.aulast=Schier&rft.aufirst=Joshua&rft.date=2010-06-01&rft.volume=38&rft.issue=6&rft.spage=667&rft.isbn=&rft.btitle=&rft.title=American+journal+of+preventive+medicine&rft.issn=1873-2607&rft_id=info:doi/10.1016%2Fj.amepre.2010.02.006 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-08-26 N1 - Date created - 2010-05-24 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.amepre.2010.02.006 ER - TY - JOUR T1 - Bromide and N-acetyl-S-(n-propyl)-L-cysteine in urine from workers exposed to 1-bromopropane solvents from vapor degreasing or adhesive manufacturing. AN - 733517917; 20229238 AB - 1-Bromopropane (1-BP) is an alternative for ozone depleting and other solvents; it is used in aerosol products, adhesives, and cleaning solvents. There is concern that 1-BP may be a reproductive and neurological toxicant. Mercapturic acid conjugates are excreted in urine from 1-BP metabolism involving debromination. The main objectives were to evaluate urinary bromide [Br(-)] and N-acetyl-S-(n-propyl)-L-cysteine (AcPrCys) for assessing 1-BP exposure in workers with low exposure. Workers' 1-BP exposures were measured in their breathing zones with gas chromatography-flame ionization detection via NIOSH 1025. Urine specimens were obtained over a 48-h period at five facilities using vapor degreasers and one adhesive manufacturer. All of the workers' urine was collected into composite samples and analyzed separately representing daily time intervals: at work, after work but before bedtime, and upon awakening. Urinary metabolites were analyzed using intra-coupled plasma-mass spectroscopy for Br(-), and high-performance liquid chromatography and electro-spray ionization mass spectroscopy for AcPrCys. Time-weighted average (TWA) geometric mean (GM) breathing zone concentrations of 1-BP at vapor degreasing facilities were 2.6 and 0.31 ppm, respectively, for workers near degreasers and those remote from degreasers. Urine metabolites showed the same trend as TWA exposures: higher levels were observed for workers near degreasers (48-h GM Br(-) = 8.9 vs. 3.7; 48-h GM AcPrCys = 1.3 vs. 0.12, respectively). Associations of Br(-) and AcPrCys concentrations with 1-BP TWA were statistically significant near degreasers (p < 0.01). This study shows that urinary Br(-) and AcPrCys are useful biomarkers of workers' 1-BP exposures using analyses sensitive enough to measure low exposure jobs. JF - International archives of occupational and environmental health AU - Hanley, Kevin William AU - Petersen, Martin R AU - Cheever, Kenneth L AU - Luo, Lian AD - National Institute for Occupational Safety and Health, Cincinnati, OH, USA. KHanley@cdc.gov Y1 - 2010/06// PY - 2010 DA - June 2010 SP - 571 EP - 584 VL - 83 IS - 5 KW - Air Pollutants, Occupational KW - 0 KW - Bromides KW - Hydrocarbons, Brominated KW - N-acetyl-S-propylcysteine KW - Solvents KW - Acetylcysteine KW - WYQ7N0BPYC KW - 1-bromopropane KW - Y9746DNE68 KW - Index Medicus KW - Socioeconomic Factors KW - Environmental Monitoring KW - Air Pollutants, Occupational -- analysis KW - Humans KW - Adult KW - Middle Aged KW - Hydrocarbons, Brominated -- analysis KW - Time Factors KW - Male KW - Female KW - Bromides -- urine KW - Acetylcysteine -- urine KW - Acetylcysteine -- analogs & derivatives KW - Solvents -- analysis KW - Manufactured Materials KW - Occupational Exposure -- analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733517917?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+archives+of+occupational+and+environmental+health&rft.atitle=Bromide+and+N-acetyl-S-%28n-propyl%29-L-cysteine+in+urine+from+workers+exposed+to+1-bromopropane+solvents+from+vapor+degreasing+or+adhesive+manufacturing.&rft.au=Hanley%2C+Kevin+William%3BPetersen%2C+Martin+R%3BCheever%2C+Kenneth+L%3BLuo%2C+Lian&rft.aulast=Hanley&rft.aufirst=Kevin&rft.date=2010-06-01&rft.volume=83&rft.issue=5&rft.spage=571&rft.isbn=&rft.btitle=&rft.title=International+archives+of+occupational+and+environmental+health&rft.issn=1432-1246&rft_id=info:doi/10.1007%2Fs00420-010-0524-4 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-08-13 N1 - Date created - 2010-05-13 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1007/s00420-010-0524-4 ER - TY - CPAPER T1 - Automated On-line Column-switching HPLC-MS/MS Method for Measuring Triclocarban and Two Triclocarban Metabolites in Urine and Serum T2 - 58th ASMS Conference on Mass Spectrometry and Allied Topics AN - 839658165; 5919414 JF - 58th ASMS Conference on Mass Spectrometry and Allied Topics AU - Ye, Sherry Y1 - 2010/05/23/ PY - 2010 DA - 2010 May 23 KW - {Q1} KW - Metabolites KW - Urine KW - Triclocarban KW - Serum KW - Automation KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839658165?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=58th+ASMS+Conference+on+Mass+Spectrometry+and+Allied+Topics&rft.atitle=Automated+On-line+Column-switching+HPLC-MS%2FMS+Method+for+Measuring+Triclocarban+and+Two+Triclocarban+Metabolites+in+Urine+and+Serum&rft.au=Ye%2C+Sherry&rft.aulast=Ye&rft.aufirst=Sherry&rft.date=2010-05-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=58th+ASMS+Conference+on+Mass+Spectrometry+and+Allied+Topics&rft.issn=&rft_id=info:doi/ L2 - http://www.asms.org/Conferences/AnnualConference/Program/tabid/113/Def LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-11 N1 - Last updated - 2011-01-14 ER - TY - JOUR T1 - Improvements in Ability to Detect Undiagnosed Diabetes by Using Information on Family History Among Adults in the United States AN - 745936987; 13150728 AB - Family history is an independent risk factor for diabetes, but it is not clear how much adding family history to other known risk factors would improve detection of undiagnosed diabetes in a population. Using the National Health and Nutrition Examination Survey for 1999-2004, the authors compared logistic regression models with established risk factors (model 1) with a model (model 2) that also included familial risk of diabetes (average, moderate, and high). Adjusted odds ratios for undiagnosed diabetes, using average familial risk as referent, were 1.7 (95% confidence interval (CI): 1.2, 2.5) and 3.8 (95% CI: 2.2, 6.3) for those with moderate and high familial risk, respectively. Model 2 was superior to model 1 in detecting undiagnosed diabetes, as reflected by several significant improvements, including weighted C statistics of 0.826 versus 0.842 (bootstrap P = 0.001) and integrated discrimination improvement of 0.012 (95% CI: 0.004, 0.030). With a risk threshold of 7.3% (sensitivity of 40% based on model 1), adding family history would identify an additional 620,000 (95% CI: 221,100, 1,020,000) cases without a significant change in false-positive fraction. Study findings suggest that adding family history of diabetes can provide significant improvements in detecting undiagnosed diabetes in the US population. Further research is needed to validate the authors' findings. JF - American Journal of Epidemiology AU - Yang, Quanhe AU - Liu, Tiebin AU - Valdez, Rodolfo AU - Moonesinghe, Ramal AU - Khoury, Muin J Y1 - 2010/05/15/ PY - 2010 DA - 2010 May 15 SP - 1079 EP - 1089 PB - Oxford University Press, Oxford Journals Health, Great Clarendon Street Oxford OX2 6DP United Kingdom VL - 171 IS - 10 SN - 0002-9262, 0002-9262 KW - Risk Abstracts UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745936987?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Epidemiology&rft.atitle=Improvements+in+Ability+to+Detect+Undiagnosed+Diabetes+by+Using+Information+on+Family+History+Among+Adults+in+the+United+States&rft.au=Yang%2C+Quanhe%3BLiu%2C+Tiebin%3BValdez%2C+Rodolfo%3BMoonesinghe%2C+Ramal%3BKhoury%2C+Muin+J&rft.aulast=Yang&rft.aufirst=Quanhe&rft.date=2010-05-15&rft.volume=171&rft.issue=10&rft.spage=1079&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Epidemiology&rft.issn=00029262&rft_id=info:doi/10.1093%2Faje%2Fkwq026 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-07-01 N1 - Last updated - 2011-12-14 DO - http://dx.doi.org/10.1093/aje/kwq026 ER - TY - JOUR T1 - Vermiculite Worker Mortality: Estimated Effects of Occupational Exposure to Libby Amphibole AN - 746309374; 13196402 AB - Objective: To examine the relationship between cumulative fiber exposure (CFE) and mortality in a retrospective cohort study of vermiculite workers exposed to Libby amphibole (n = 1862). Methods: Extended Cox regression was used to estimate the hazards associated with CFE as a time-dependent covariate of multiple-cause mortality. Results: The Cox models for mesothelioma, asbestosis, lung cancer, and non-malignant respiratory disease were significant with rate ratios that increased monotonically with CFE. The model for deaths due to cardiovascular disease was also significant (rate ratio for CFE .44.0 f/cc-y vs <1.4 f/cc-y was 1.5; 95% confidence interval = 1.1 to 2.0). Conclusions: By using a within-cohort comparison, the results demonstrate a clear exposure-response relationship between CFE and mortality from asbestos-related causes. The finding of an association between CFE and cardiovascular mortality suggests persons exposed to Libby amphibole should be monitored for this outcome. JF - Journal of Occupational and Environmental Medicine AU - Larson, T C AU - Antao, V C AU - Bove, F J AD - DHS/ATSDR, 4770 Buford Highway NE, MS F57, Atlanta, GA 30341, USA, th13@cdc.gov Y1 - 2010/05// PY - 2010 DA - May 2010 SP - 555 EP - 560 VL - 52 IS - 5 SN - 1076-2752, 1076-2752 KW - Toxicology Abstracts; Health & Safety Science Abstracts KW - Mortality KW - Respiratory diseases KW - Asbestosis KW - Models KW - Fibers KW - Dose-response effects KW - mesothelioma KW - Cardiovascular diseases KW - Occupational exposure KW - Lung cancer KW - H 1000:Occupational Safety and Health KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/746309374?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Vermiculite+Worker+Mortality%3A+Estimated+Effects+of+Occupational+Exposure+to+Libby+Amphibole&rft.au=Larson%2C+T+C%3BAntao%2C+V+C%3BBove%2C+F+J&rft.aulast=Larson&rft.aufirst=T&rft.date=2010-05-01&rft.volume=52&rft.issue=5&rft.spage=555&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e3181dc6d45 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-07-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Fibers; Mortality; Dose-response effects; mesothelioma; Cardiovascular diseases; Asbestosis; Occupational exposure; Lung cancer; Models; Respiratory diseases DO - http://dx.doi.org/10.1097/JOM.0b013e3181dc6d45 ER - TY - JOUR T1 - Staphylococcus aureus community-onset pneumonia in patients admitted to children's hospitals during autumn and winter of 2006-2007 AN - 744719873; 12582011 AB - Staphylococcus aureus is a relatively uncommon cause of community-onset pneumonia (COP) that may complicate influenza infection. We reviewed admissions to children's hospitals to describe more systematically this entity. Records of patients hospitalized at three children's hospitals between 1 October 2006 and 30 April 2007 who had a positive S. aureus culture from a sterile site or respiratory specimen were reviewed and data were abstracted for episodes of primary S. aureus COP. Overall, 30 episodes met criteria for primary S. aureus COP; 12 (41%) involved methicillin-resistant S. aureus. Patients in 11 (37%) episodes were seen by a healthcare provider for their symptoms prior to hospital admission; three received an antimicrobial, none of which had activity against the S. aureus isolated. Mechanical ventilation was required in 21 (70%) episodes; five (17%) patients died. When evaluating patients with severe COP, providers should be aware of the potential for S. aureus, including methicillin-resistant strains. JF - Epidemiology and Infection AU - Kallen, A J AU - Reed, C AU - Patton, M AU - Arnold, Ke AU - Finelli, L AU - Hageman, J AD - Epidemic Intelligence Service, Office of Workforce and Career Development, Atlanta, GA, USA, AKallen@cdc.gov Y1 - 2010/05// PY - 2010 DA - May 2010 SP - 666 EP - 672 PB - Cambridge University Press, The Edinburgh Building, Cambridge CB2 2RU UK VL - 138 IS - 5 SN - 0950-2688, 0950-2688 KW - Microbiology Abstracts B: Bacteriology KW - Influenza KW - Data processing KW - Ventilation KW - Drug resistance KW - Staphylococcus aureus KW - Children KW - Infection KW - Pneumonia KW - Hospitals KW - Antimicrobial agents KW - J 02310:Genetics & Taxonomy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/744719873?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Epidemiology+and+Infection&rft.atitle=Staphylococcus+aureus+community-onset+pneumonia+in+patients+admitted+to+children%27s+hospitals+during+autumn+and+winter+of+2006-2007&rft.au=Kallen%2C+A+J%3BReed%2C+C%3BPatton%2C+M%3BArnold%2C+Ke%3BFinelli%2C+L%3BHageman%2C+J&rft.aulast=Kallen&rft.aufirst=A&rft.date=2010-05-01&rft.volume=138&rft.issue=5&rft.spage=666&rft.isbn=&rft.btitle=&rft.title=Epidemiology+and+Infection&rft.issn=09502688&rft_id=info:doi/10.1017%2FS095026880999135X LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-01 N1 - Number of references - 21 N1 - Last updated - 2014-04-17 N1 - SubjectsTermNotLitGenreText - Influenza; Data processing; Ventilation; Drug resistance; Infection; Children; Pneumonia; Antimicrobial agents; Hospitals; Staphylococcus aureus DO - http://dx.doi.org/10.1017/S095026880999135X ER - TY - JOUR T1 - Detection of E119V and E119I Mutations in Influenza A (H3N2) Viruses Isolated from an Immunocompromised Patient: Challenges in Diagnosis of Oseltamivir Resistance AN - 744674039; 12676399 AB - The clinical use of the neuraminidase inhibitor (NAI) oseltamivir is associated with the emergence of drug resistance resulting from subtype-specific neuraminidase (NA) mutations. The influenza A/Texas/12/2007 (H3N2) virus isolated from an oseltamivir-treated immunocompromised patient exhibited reduced susceptibility to oseltamivir in the chemiluminescent neuraminidase inhibition (NI) assay (60-fold increase in its 50% inhibitory concentration [IC50] compared to that for a control virus). When further propagated in cell culture, the isolate maintained reduced susceptibility to oseltamivir in both chemiluminescent and fluorescent NI assays (50- and 350-fold increases in IC50, respectively). Sequencing analysis of the isolate revealed a mix of nucleotides coding for amino acids at position 119 of the NA [E119(V/I)]. Plaque purification of the isolate yielded E119V and E119I variants, both exhibiting reduced susceptibility to oseltamivir. The E119I variant also showed decreased susceptibility to zanamivir and the investigational NAIs peramivir and A-315675. The emergence of E119V variants in oseltamivir-treated patients has been previously reported; however, the E119I mutation detected here is a novel one which reduces susceptibility to several NAIs. Both mutations were not detected in unpropagated original clinical specimens using either conventional sequencing or pyrosequencing, suggesting that these variants were present in very low proportions (<10%) in clinical specimens and gained dominance after virus propagation in MDCK cells. All virus isolates recovered from the patient were resistant to adamantanes. Our findings highlight the potential for emergence and persistence of multidrug-resistant influenza viruses in oseltamivir-treated immunocompromised subjects and also highlight challenges for drug resistance diagnosis due to the genetic instability of the virus population upon propagation in cell culture. JF - Antimicrobial Agents & Chemotherapy AU - Okomo-Adhiambo, Margaret AU - Demmler-Harrison, Gail J AU - Deyde, Varough M AU - Sheu, Tiffany G AU - Xu, Xiyan AU - Klimov, Alexander I AU - Gubareva, Larisa V AD - Virus Surveillance and Diagnosis Branch, Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, lgubareva@cdc.gov Y1 - 2010/05// PY - 2010 DA - May 2010 SP - 1834 EP - 1841 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 54 IS - 5 SN - 0066-4804, 0066-4804 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Virology & AIDS Abstracts KW - Nucleotide sequence KW - Influenza A KW - Drug resistance KW - Exo-a-sialidase KW - Cell culture KW - Zanamivir KW - Nucleotides KW - Dominance KW - Oseltamivir KW - Immunocompromised hosts KW - Plaques KW - Purification KW - Mutation KW - A 01340:Antibiotics & Antimicrobials KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/744674039?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Detection+of+E119V+and+E119I+Mutations+in+Influenza+A+%28H3N2%29+Viruses+Isolated+from+an+Immunocompromised+Patient%3A+Challenges+in+Diagnosis+of+Oseltamivir+Resistance&rft.au=Okomo-Adhiambo%2C+Margaret%3BDemmler-Harrison%2C+Gail+J%3BDeyde%2C+Varough+M%3BSheu%2C+Tiffany+G%3BXu%2C+Xiyan%3BKlimov%2C+Alexander+I%3BGubareva%2C+Larisa+V&rft.aulast=Okomo-Adhiambo&rft.aufirst=Margaret&rft.date=2010-05-01&rft.volume=54&rft.issue=5&rft.spage=1834&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.01608-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-01 N1 - Number of references - 39 N1 - Last updated - 2015-09-30 N1 - SubjectsTermNotLitGenreText - Drug resistance; Influenza A; Nucleotide sequence; Exo-a-sialidase; Cell culture; Zanamivir; Nucleotides; Oseltamivir; Dominance; Immunocompromised hosts; Plaques; Purification; Mutation DO - http://dx.doi.org/10.1128/AAC.01608-09 ER - TY - JOUR T1 - Long-term Health and Economic Impact of Preventing and Reducing Overweight and Obesity in Adolescence AN - 744625383; 13043842 AB - Purpose - Using data from the 2000 National Medical Expenditure Panel Survey and estimates from published studies, this study projected the long-term health and economic impacts of preventing and reducing overweight and obesity in today's adolescents. Methods - We developed a body mass index progression model to project the impact of a 1% point reduction in both overweight and obese adolescents aged 16-17 years at present on the number of nonoverweight, overweight, and obese adults at age 40 years. We then estimated its impact on the lifetime medical costs and quality-adjusted life years (QALYs) after age 40. Medical costs (in 2007 dollars) and QALYs were discounted to age 17 years. Results - A 1% point reduction in both overweight and obese adolescents ages 16-17 years at present could reduce the number of obese adults by 52,821 in the future. As a result, lifetime medical care costs after age 40 years would decrease by $586 million and lifetime QALYs would increase by 47,138. In the worst case scenario, the 1% point reduction would lower medical costs by $463 million and increase QALYs by 34,394; in the best case scenario, it would reduce medical costs by $691 million and increase QALYs by 57,149. Conclusions - Obesity prevention in adolescents goes beyond its immediate benefits; it can also reduce medical costs and increase QALYs substantially in later life. Therefore, it is important to include long-term health and economic benefits when quantifying the impact of obesity prevention in adolescents. JF - Journal of Adolescent Health AU - Wang, Li Y AU - Denniston, Maxine AU - Lee, Sarah AU - Galuska, Deborah AU - Lowry, Richard AD - Division of Adolescent and School Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, lgw0@cdc.gov Y1 - 2010/05// PY - 2010 DA - May 2010 SP - 467 EP - 473 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 46 IS - 5 SN - 1054-139X, 1054-139X KW - Health & Safety Science Abstracts; Risk Abstracts KW - Obesity prevention KW - Adolescents KW - Long-term impact KW - Medical costs KW - Quality-adjusted life years KW - Age KW - body mass KW - Economics KW - obesity KW - prevention KW - H 12000:Epidemiology and Public Health KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/744625383?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Adolescent+Health&rft.atitle=Long-term+Health+and+Economic+Impact+of+Preventing+and+Reducing+Overweight+and+Obesity+in+Adolescence&rft.au=Wang%2C+Li+Y%3BDenniston%2C+Maxine%3BLee%2C+Sarah%3BGaluska%2C+Deborah%3BLowry%2C+Richard&rft.aulast=Wang&rft.aufirst=Li&rft.date=2010-05-01&rft.volume=46&rft.issue=5&rft.spage=467&rft.isbn=&rft.btitle=&rft.title=Journal+of+Adolescent+Health&rft.issn=1054139X&rft_id=info:doi/10.1016%2Fj.jadohealth.2009.11.204 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Age; body mass; Economics; prevention; obesity; Adolescents DO - http://dx.doi.org/10.1016/j.jadohealth.2009.11.204 ER - TY - JOUR T1 - Socioeconomic Status and Risk of Diabetes-Related Mortality in the U.S. AN - 742956400; 2010-522165 AB - Objective. We examined disparities in diabetes-related mortality for socioeconomic status (SES) groups in nationally representative U.S. samples. Methods. We analyzed National Health Interview Survey respondents linked to their death records and included those eligible for mortality follow-up who were aged 25 years and older at the time of interview and not missing information on covariates (n=527,426). We measured SES by education and family income. There were 5,613 diabetes-related deaths. Results. Having less than a high school education was associated with a twofold higher mortality from diabetes, after controlling for age, gender, race/ethnicity, marital status, and body mass index, compared with adults with a college degree or higher education level (relative hazard [RH] = 2.05, 95% confidence interval [Cl] 1.78, 2.35). Having a family income below poverty level was associated with a twofold higher mortality after adjustments compared with adults with the highest family incomes (RH=2.41, 95% CI 2.05, 2.84). Approximately one-quarter of the excess risk among those in the lowest SES categories was explained by adjusting for potential confounders. Conclusion. Findings from this nationally representative cohort demonstrate a socioeconomic gradient in diabetes-related mortality, with both education and income being important determinants of the risk of death. Adapted from the source document. JF - Public Health Reports AU - Saydah, Sharon AU - Lochner, Kimberly AD - Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Division of Diabetes Translation, 3311 Toledo Rd., Hyattsville, MD 20782; tel. 301-458-4183; fax 301-458-4025 ssaydah@cdc.gov Y1 - 2010/05// PY - 2010 DA - May 2010 SP - 377 EP - 388 PB - Oxford University Press, UK VL - 125 IS - 3 SN - 0033-3549, 0033-3549 KW - Health conditions and policy - Diseases and disorders KW - Population groups, population policy, and demographics - Demography and census KW - Social conditions and policy - Public safety and security KW - Social conditions and policy - Social research KW - Health conditions and policy - Health and health policy KW - Social conditions and policy - Marriage and family life KW - Social conditions and policy - Social conditions and problems KW - Economic conditions and policy - Economic conditions KW - Education and education policy - Education KW - Obesity KW - Risk KW - Mortality KW - Education KW - Socioeconomic status KW - Marital status KW - Poverty KW - Health surveys KW - Child health KW - Diabetes KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742956400?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Public+Health+Reports&rft.atitle=Socioeconomic+Status+and+Risk+of+Diabetes-Related+Mortality+in+the+U.S.&rft.au=Saydah%2C+Sharon%3BLochner%2C+Kimberly&rft.aulast=Saydah&rft.aufirst=Sharon&rft.date=2010-05-01&rft.volume=125&rft.issue=3&rft.spage=377&rft.isbn=&rft.btitle=&rft.title=Public+Health+Reports&rft.issn=00333549&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2010-06-07 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Diabetes; Mortality; Risk; Socioeconomic status; Health surveys; Child health; Marital status; Obesity; Education; Poverty ER - TY - JOUR T1 - Folic Acid Intake Among U.S. Women Aged 15-44 Years, National Health and Nutrition Examination Survey, 2003-2006 AN - 742724368; 201014543 AB - In 1998, the IOM recommended all women capable of becoming pregnant consume 400 (mu)g of folic acid daily to prevent neural tube defects (NTDs). Purpose This paper aims to describe how different sources of folic acid contribute to achieving the recommended usual daily intake. Methods Data on 2617 nonpregnant U.S. women aged 15-44 years from the 2003-2004 and 2005-2006 National Health and Nutrition Examination Surveys were analyzed in 2009. The usual daily folic acid intake from diet and supplements accounting for measurement error; the proportion of women consuming the recommended usual intake; and the adjusted associations of recommended intake with multiple characteristics were estimated. Results Overall, 24% of nonpregnant U.S. women of childbearing age consumed the recommended usual intake (95% CI=20%, 27%). Intake was highest among non-Hispanic white women (30%), followed by Mexican-American (17%) and non-Hispanic black women (9%). Among women who used supplements with folic acid, 72% (95% CI=65%, 79%) consumed the recommended usual intake. Use of supplements was the strongest determinant (unadjusted prevalence ratio [PR]: 10.2, 95% CI=7.1, 14.7) of recommended intake, mediating associations of other characteristics. Among the 68% of women who did not use supplements, consumption of cereals with folic acid and having diabetes were the strongest determinants of recommended usual intake (PRs=20.2 and 0.10, respectively). Conclusions Given that consumption of folic acid is an important public health goal to prevent NTDs, an evaluation of strategies, beyond recommendations that women consume supplements, is needed. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Tinker, Sarah C AU - Cogswell, Mary E AU - Devine, Owen AU - Berry, Robert J AD - National Center on Birth Defects and Developmental Disabilities, CDC, Atlanta, Georgia Y1 - 2010/05// PY - 2010 DA - May 2010 SP - 534 EP - 542 PB - Elsevier Science, New York NY VL - 38 IS - 5 SN - 0749-3797, 0749-3797 KW - Consumption KW - Health KW - Pregnant women KW - Folic acid KW - Nutrition KW - Public health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742724368?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Folic+Acid+Intake+Among+U.S.+Women+Aged+15-44+Years%2C+National+Health+and+Nutrition+Examination+Survey%2C+2003-2006&rft.au=Tinker%2C+Sarah+C%3BCogswell%2C+Mary+E%3BDevine%2C+Owen%3BBerry%2C+Robert+J&rft.aulast=Tinker&rft.aufirst=Sarah&rft.date=2010-05-01&rft.volume=38&rft.issue=5&rft.spage=534&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2010.01.025 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-10-21 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Pregnant women; Folic acid; Consumption; Nutrition; Health; Public health DO - http://dx.doi.org/10.1016/j.amepre.2010.01.025 ER - TY - JOUR T1 - Quantification of monofluoroacetate and monochloroacetate in human urine by isotope dilution liquid chromatography tandem mass spectrometry. AN - 733909171; 20356806 AB - The rodenticide monofluoroacetate (MFA) and monochloroacetate (MCA), a chemical intermediate from several chemical syntheses, have been identified as potential agents of chemical terrorism due to their high toxicity. In preparation for response to poisonings and mass exposures, we have developed a quantification method using isotopic dilution to determine MFA and MCA in urine from 50 to 5000 ng/mL. Both analytes were extracted from urine using solid-phase extraction; extraction recoveries were 62% (MFA) and 76% (MCA). The extracts were then separated with isocratic high-performance liquid chromatography and identified using electrospray ionization tandem mass spectrometry, with detection limits of 0.9 and 7.0 ng/mL for MFA and MCA, respectively. Selectivity was established for both analytes with unique chromatographic retention times which were correlated with isotopically labeled internal standards and the use of two mass spectral transitions for each compound. The intra-day variability was less than 5% for both analytes and the inter-day variability was 7% for MFA and 6% for MCA. 2010 Elsevier B.V. All rights reserved. JF - Journal of chromatography. B, Analytical technologies in the biomedical and life sciences AU - Hamelin, Elizabeth I AU - Mawhinney, Douglas B AU - Parry, Ritchard AU - Kobelski, Robert J AD - Battelle Memorial Institute, Century Plaza 1, 2987 Clairmont Road, Suite 450, Atlanta, GA 30329, USA. ehamelin@cdc.gov Y1 - 2010/05/01/ PY - 2010 DA - 2010 May 01 SP - 1045 EP - 1050 VL - 878 IS - 15-16 KW - Acetates KW - 0 KW - Fluoroacetates KW - Rodenticides KW - chloroacetic acid KW - 5GD84Y125G KW - fluoroacetic acid KW - AP1JV9U41M KW - Index Medicus KW - Sensitivity and Specificity KW - Drug Stability KW - Reproducibility of Results KW - Hydrogen-Ion Concentration KW - Humans KW - Solid Phase Extraction KW - Fluoroacetates -- urine KW - Tandem Mass Spectrometry -- methods KW - Chromatography, High Pressure Liquid -- methods KW - Rodenticides -- urine KW - Acetates -- urine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733909171?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+chromatography.+B%2C+Analytical+technologies+in+the+biomedical+and+life+sciences&rft.atitle=Quantification+of+monofluoroacetate+and+monochloroacetate+in+human+urine+by+isotope+dilution+liquid+chromatography+tandem+mass+spectrometry.&rft.au=Hamelin%2C+Elizabeth+I%3BMawhinney%2C+Douglas+B%3BParry%2C+Ritchard%3BKobelski%2C+Robert+J&rft.aulast=Hamelin&rft.aufirst=Elizabeth&rft.date=2010-05-01&rft.volume=878&rft.issue=15-16&rft.spage=1045&rft.isbn=&rft.btitle=&rft.title=Journal+of+chromatography.+B%2C+Analytical+technologies+in+the+biomedical+and+life+sciences&rft.issn=1873-376X&rft_id=info:doi/10.1016%2Fj.jchromb.2010.03.008 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-08-02 N1 - Date created - 2010-04-23 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.jchromb.2010.03.008 ER - TY - JOUR T1 - Lessons learned from the investigation of a cluster of cutaneous anthrax cases in Connecticut. AN - 733847420; 20357605 AB - In 2007, two cases of cutaneous anthrax associated with West African drum making were reported in Connecticut in a drum-maker and his child. Although both cases were due to exposure to naturally occurring Bacillus anthracis from imported animal hides, ensuing investigative and remediation efforts were affected by the intentional B anthracis attacks in 2001. To share our experience of responding to an outbreak of anthrax in the biologic terrorism preparedness era, we summarize Connecticut's investigation and describe lessons learned. Laboratory capacity to rapidly assist in diagnosing anthrax, collaborative associations between epidemiologists and law enforcement personnel, and training in use of the Incident Command System, all these a result of public health preparedness, enhanced the initial recognition and subsequent investigation of these anthrax cases. However, without established guidelines for environmental risk assessment and remediation of private residences contaminated by B anthracis, challenges were encountered that resulted in a conservative and expensive approach to remediation. Without a more rigorous approach to ensuring that B anthracis spore-free hides are used, the making of animal hide drums is likely to pose a continuing risk for anthrax to those working with contaminated hides and those exposed to subsequently contaminated environments. JF - Journal of public health management and practice : JPHMP AU - Guh, Alice AU - Heyman, Marian L AU - Barden, Diane AU - Fontana, John AU - Hadler, James L AD - Centers of Disease Control and Prevention, Atlanta, Georgia 30333, USA. aguh@cdc.gov PY - 2010 SP - 201 EP - 210 VL - 16 IS - 3 KW - Health technology assessment KW - Humans KW - Cheek -- pathology KW - Female KW - Connecticut KW - Skin Diseases, Infectious -- pathology KW - Anthrax -- pathology KW - Facial Dermatoses -- pathology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733847420?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+public+health+management+and+practice+%3A+JPHMP&rft.atitle=Lessons+learned+from+the+investigation+of+a+cluster+of+cutaneous+anthrax+cases+in+Connecticut.&rft.au=Guh%2C+Alice%3BHeyman%2C+Marian+L%3BBarden%2C+Diane%3BFontana%2C+John%3BHadler%2C+James+L&rft.aulast=Guh&rft.aufirst=Alice&rft.date=2010-05-01&rft.volume=16&rft.issue=3&rft.spage=201&rft.isbn=&rft.btitle=&rft.title=Journal+of+public+health+management+and+practice+%3A+JPHMP&rft.issn=1550-5022&rft_id=info:doi/10.1097%2FPHH.0b013e3181ca650d LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2012-05-09 N1 - Date created - 2010-04-01 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1097/PHH.0b013e3181ca650d ER - TY - JOUR T1 - The Relative Influence of Different Domains of Social Connectedness on Self-Directed Violence in Adolescence AN - 1008826941; 16466274 AB - Previous research has linked greater social connectedness with a lowered risk of self-directed violence among adolescents. However, few studies have analyzed the comparative strength of different domains of connectedness (e.g., family, peers and school) to determine where limited resources might best be focused. Data to address that gap were taken from the Centers for Disease Control and Prevention's Student Health and Safety Survey, administered to 4,131 7th-12th graders (51.5% female; 43.8% Hispanic; 22.6% African American or Black). Logistic regressions (controlling for age, gender, race/ethnicity, family structure, academic performance, and depressive symptoms) suggest that family connectedness was a stronger predictor than connectedness to peers, school, or adults at school for non-suicidal self-harm, suicidal ideation, suicide plans, and non-fatal suicidal behavior. In some analyses, peer connectedness was unexpectedly a risk factor. Results have implications for prevention of suicide in adolescence, especially in the context of the current trend towards school-based prevention programs. JF - Journal of Youth and Adolescence AU - Kaminski, Jennifer W AU - Puddy, Richard W AU - Hall, Diane M AU - Cashman, Sandra Y AU - Crosby, Alexander E AU - Ortega, LaVonne AG AD - Division of Violence Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, 4770 Buford Hwy NE, MS-F63, Atlanta, GA, 30341, USA, JKaminski@cdc.gov Y1 - 2010/05// PY - 2010 DA - May 2010 SP - 460 EP - 473 PB - Springer Science+Business Media, Van Godewijckstraat 30 Dordrecht 3311 GX Netherlands VL - 39 IS - 5 SN - 0047-2891, 0047-2891 KW - Risk Abstracts KW - Age KW - schools KW - Risk factors KW - Gender KW - prevention KW - Violence KW - Ethnic groups KW - suicide KW - Adolescents KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1008826941?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Youth+and+Adolescence&rft.atitle=The+Relative+Influence+of+Different+Domains+of+Social+Connectedness+on+Self-Directed+Violence+in+Adolescence&rft.au=Kaminski%2C+Jennifer+W%3BPuddy%2C+Richard+W%3BHall%2C+Diane+M%3BCashman%2C+Sandra+Y%3BCrosby%2C+Alexander+E%3BOrtega%2C+LaVonne+AG&rft.aulast=Kaminski&rft.aufirst=Jennifer&rft.date=2010-05-01&rft.volume=39&rft.issue=5&rft.spage=460&rft.isbn=&rft.btitle=&rft.title=Journal+of+Youth+and+Adolescence&rft.issn=00472891&rft_id=info:doi/10.1007%2Fs10964-009-9472-2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-04-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Age; schools; Risk factors; Gender; prevention; Violence; Adolescents; suicide; Ethnic groups DO - http://dx.doi.org/10.1007/s10964-009-9472-2 ER - TY - NEWS T1 - Black mother less likely to breastfeed AN - 347791301 AB - A state-by-state analysis released by the Center for Disease Control and Prevention indicates that 54 percent of African-American women attempt to breast-feed their babies, compared to 80 percent of Hispanics and 74 percent of whites. JF - Westside Gazette AU - Anonymous Y1 - 2010///Apr 22-Apr 28, PY - 2010 DA - Apr 22-Apr 28, 2010 SP - 13 CY - Ft. Lauderdale, Fla. IS - 10 KW - Ethnic Interests KW - Mothers KW - African Americans KW - Breastfeeding & lactation KW - Statistics KW - Women KW - United States--US UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/347791301?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aethnicnewswatch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Westside+Gazette&rft.atitle=Black+mother+less+likely+to+breastfeed&rft.au=Anonymous&rft.aulast=Anonymous&rft.aufirst=&rft.date=2010-04-22&rft.volume=39&rft.issue=10&rft.spage=13&rft.isbn=&rft.btitle=&rft.title=Westside+Gazette&rft.issn=&rft_id=info:doi/ LA - English DB - Ethnic NewsWatch N1 - Name - Centers for Disease Control & Prevention--CDC N1 - Copyright - Copyright The Gazette Newspaper Group Apr 22-Apr 28, 2010 N1 - Last updated - 2011-11-02 ER - TY - CPAPER T1 - Evaluating IIS Best Practice Operational Guidelines: Emerging Trends and Challenges T2 - 44th National Immunization Conference (NIC 2010) AN - 754208142; 5751653 JF - 44th National Immunization Conference (NIC 2010) AU - Williams, Warren AU - Lowery, Elaine AU - Lyalin, David AU - Lambrecht, Nichole AU - Riddick, Sherry AU - Sutliff, Cynthia AU - Papadouka, Vikki Y1 - 2010/04/19/ PY - 2010 DA - 2010 Apr 19 KW - Guidelines KW - Best practices KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754208142?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=44th+National+Immunization+Conference+%28NIC+2010%29&rft.atitle=Evaluating+IIS+Best+Practice+Operational+Guidelines%3A+Emerging+Trends+and+Challenges&rft.au=Williams%2C+Warren%3BLowery%2C+Elaine%3BLyalin%2C+David%3BLambrecht%2C+Nichole%3BRiddick%2C+Sherry%3BSutliff%2C+Cynthia%3BPapadouka%2C+Vikki&rft.aulast=Williams&rft.aufirst=Warren&rft.date=2010-04-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=44th+National+Immunization+Conference+%28NIC+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://cdc.confex.com/cdc/nic2010/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - Inhibition of Human Hepatitis B Virus (Hbv) by a Novel Non-Nucleosidic Compound T2 - 45th Annual Meeting of the European Association for the Study of the Liver (EASL 2010) AN - 754281363; 5831158 JF - 45th Annual Meeting of the European Association for the Study of the Liver (EASL 2010) AU - Wang, X.-Y. AU - Wang, J.-H. AU - Zhang, H.-H. AU - Fei, R AU - Wei, L AU - Wang, Y AU - Chen, H.-S. Y1 - 2010/04/14/ PY - 2010 DA - 2010 Apr 14 KW - Hepatitis B KW - Hepatitis B virus KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754281363?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=45th+Annual+Meeting+of+the+European+Association+for+the+Study+of+the+Liver+%28EASL+2010%29&rft.atitle=Inhibition+of+Human+Hepatitis+B+Virus+%28Hbv%29+by+a+Novel+Non-Nucleosidic+Compound&rft.au=Wang%2C+X.-Y.%3BWang%2C+J.-H.%3BZhang%2C+H.-H.%3BFei%2C+R%3BWei%2C+L%3BWang%2C+Y%3BChen%2C+H.-S.&rft.aulast=Wang&rft.aufirst=X.-Y.&rft.date=2010-04-14&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=45th+Annual+Meeting+of+the+European+Association+for+the+Study+of+the+Liver+%28EASL+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://www.kenes.com/easl2010/orals/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - JOUR T1 - Protecting and Enhancing Health: Community Engagement, Collaborations, and Incentives for Prevention AN - 902082630; 201104962 AB - The US health care system and its reform has become a focal point of public debate, engaging many who traditionally have not participated in the dialogue around population health needs and resources. In this essay, we discuss aspects of a transformed health care system that addresses major health needs of Americans through health promotion, disease prevention, and personal health care. We bring attention to the role of communities and patients on the health issues with a focus on public (population) health practice, emphasizing collaboration among government health agencies at all levels and other health-related public and private organizations. Adapted from the source document. JF - The Journal of Primary Prevention AU - Simoes, Eduardo J AU - Sumaya, Ciro V AD - National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Hwy, NE, MS K-45, Atlanta, GA, 30341, USA esimoes@cdc.gov Y1 - 2010/04// PY - 2010 DA - April 2010 SP - 21 EP - 29 PB - Springer Science+Business Media, Dordrecht, The Netherlands VL - 31 IS - 1-2 SN - 0278-095X, 0278-095X KW - Prevention KW - Public Health KW - Government Agencies KW - Cooperation KW - Health Problems KW - United States of America KW - Health KW - Reform KW - Health Care Services KW - article KW - 7211: health policy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/902082630?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocialservices&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+Primary+Prevention&rft.atitle=Protecting+and+Enhancing+Health%3A+Community+Engagement%2C+Collaborations%2C+and+Incentives+for+Prevention&rft.au=Simoes%2C+Eduardo+J%3BSumaya%2C+Ciro+V&rft.aulast=Simoes&rft.aufirst=Eduardo&rft.date=2010-04-01&rft.volume=31&rft.issue=1-2&rft.spage=21&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+Primary+Prevention&rft.issn=0278095X&rft_id=info:doi/10.1007%2Fs10935-010-0201-0 LA - English DB - Social Services Abstracts N1 - Date revised - 2011-11-02 N1 - Last updated - 2016-09-28 N1 - CODEN - JPPRDT N1 - SubjectsTermNotLitGenreText - Health Care Services; Health; Cooperation; Prevention; Public Health; Health Problems; Government Agencies; Reform; United States of America DO - http://dx.doi.org/10.1007/s10935-010-0201-0 ER - TY - JOUR T1 - Visual performance for trip hazard detection when using incandescent and led miner cap lamps AN - 754531720; 13211686 AB - Introduction - Accident data for 2003-2007 indicate that slip, trip, and falls (STFs) are the second leading accident class (17.8%, n = 2,441) of lost-time injuries in underground mining. Proper lighting plays a critical role in enabling miners to detect STF hazards in this environment. Often, the only lighting available to the miner is from a cap lamp worn on the miner's helmet. The focus of this research was to determine if the spectral content of light from light-emitting diode (LED) cap lamps enabled visual performance improvements for the detection of tripping hazards as compared to incandescent cap lamps that are traditionally used in underground mining. A secondary objective was to determine the effects of aging on visual performance. Method - The visual performance of 30 subjects was quantified by measuring each subject's speed and accuracy in detecting objects positioned on the floor both in the near field, at 1.83 meters, and far field, at 3.66 meters. Near field objects were positioned at 0 degrees and +/- 20 degrees off axis, while far field objects were positioned at 0 degrees and +/- 10 degrees off axis. Three age groups were designated: group A consisted of subjects 18 to 25 years old, group B consisted of subjects 40 to 50 years old, and group C consisted of subjects 51 years and older. Results - Results of the visual performance comparison for a commercially available LED, a prototype LED, and an incandescent cap lamp indicate that the location of objects on the floor, the type of cap lamp used, and subject age all had significant influences on the time required to identify potential trip hazards. The LED-based cap lamps enabled detection times that were an average of 0.96 seconds faster compared to the incandescent cap lamp. Use of the LED cap lamps resulted in average detection times that were about 13.6% faster than those recorded for the incandescent cap lamp. The visual performance differences between the commercially available LED and prototype LED cap lamp were not statistically significant. Impact on Industry - It can be inferred from this data that the spectral content from LED-based cap lamps could enable significant visual performance improvements for miners in the detection of trip hazards. JF - Journal of Safety Research AU - Sammarco, John J AU - Gallagher, Sean AU - Reyes, Miguel AD - National Institute for Occupational Safety and Health, Pittsburgh Research Laboratory, 626 Cochrans Mill Road, P.O. Box 18070, Pittsburgh, PA 15236, Jsammarco@cdc.govSgallagher@cdc.govMreyes@cdc.gov Y1 - 2010/04// PY - 2010 DA - Apr 2010 SP - 85 EP - 91 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK VL - 41 IS - 2 SN - 0022-4375, 0022-4375 KW - Health & Safety Science Abstracts KW - age groups KW - Age KW - Injuries KW - prototypes KW - Occupational safety KW - Lighting KW - Hazards KW - Accidents KW - helmets KW - Mining KW - aging KW - H 11000:Diseases/Injuries/Trauma UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754531720?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Safety+Research&rft.atitle=Visual+performance+for+trip+hazard+detection+when+using+incandescent+and+led+miner+cap+lamps&rft.au=Sammarco%2C+John+J%3BGallagher%2C+Sean%3BReyes%2C+Miguel&rft.aulast=Sammarco&rft.aufirst=John&rft.date=2010-04-01&rft.volume=41&rft.issue=2&rft.spage=85&rft.isbn=&rft.btitle=&rft.title=Journal+of+Safety+Research&rft.issn=00224375&rft_id=info:doi/10.1016%2Fj.jsr.2010.02.007 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Hazards; age groups; Age; Accidents; Injuries; prototypes; helmets; Occupational safety; Lighting; Mining; aging DO - http://dx.doi.org/10.1016/j.jsr.2010.02.007 ER - TY - JOUR T1 - Restraint use and seating position among children less than 13 years of age: Is it still a problem? AN - 754531706; 13211684 AB - Introduction - The purpose of this study was to calculate national estimates and examine the extent to which children prematurely use adult seat belts and ride in the front seat of a vehicle during a 30 day period. Methods - Data were obtained from a nationally representative cross-sectional random-digit-dial telephone survey that included child-specific questions on motor vehicle restraint use and seating position. Results - Among children less than 13 years, parents reported an estimated 618,337 who rode unrestrained and more than one million who rode in the front seat of a vehicle at least some of the time in the past 30 days. During the same time period, close to 11 million children 8 years and younger reportedly used only adult seat belts. Discussion - Our results highlight the need for continued outreach to parents regarding optimal restraint use and rear seating position for children every trip, every time. JF - Journal of Safety Research AU - Greenspan, Arlene I AU - Dellinger, Ann M AU - Chen, Jieru AD - Division of Unintentional Injury Prevention, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Mailstop F-62, Atlanta, GA 30341, agreenspan@cdc.govadellinger@cdc.govchen@cdc.gov Y1 - 2010/04// PY - 2010 DA - Apr 2010 SP - 183 EP - 185 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK VL - 41 IS - 2 SN - 0022-4375, 0022-4375 KW - Health & Safety Science Abstracts KW - Age KW - Motor vehicles KW - Children KW - Protective equipment KW - seat belts KW - H 2000:Transportation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754531706?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Safety+Research&rft.atitle=Restraint+use+and+seating+position+among+children+less+than+13+years+of+age%3A+Is+it+still+a+problem%3F&rft.au=Greenspan%2C+Arlene+I%3BDellinger%2C+Ann+M%3BChen%2C+Jieru&rft.aulast=Greenspan&rft.aufirst=Arlene&rft.date=2010-04-01&rft.volume=41&rft.issue=2&rft.spage=183&rft.isbn=&rft.btitle=&rft.title=Journal+of+Safety+Research&rft.issn=00224375&rft_id=info:doi/10.1016%2Fj.jsr.2010.03.001 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Age; Motor vehicles; Children; Protective equipment; seat belts DO - http://dx.doi.org/10.1016/j.jsr.2010.03.001 ER - TY - JOUR T1 - Implications of the One Health Paradigm for Clinical Microbiology AN - 746078297; 13042988 AB - Clinical microbiologists have a new and unique opportunity to increase our value to health care by broadening how we think about disease processes and asking ourselves what we can do to help resolve a disease, assist in tracking a cause, or even predict an outbreak before it occurs. Human health, animal health (both wildlife and domestic animals), and environmental health are forever bound together. The convergence of people, animals, and the environment defines the parameters of One Health and directs attention to the impact this overlap has on public health, disease detection, and control. One Health (sometimes referred to as One Medicine) is a concept that promotes, improves, and defends the health and well-being of all species through the integration of the sciences of human medicine, veterinary medicine, and environmental studies. As microbiologists, we need to be aware of this One Health concept and how it can positively impact our profession by allowing us to be more productive members of the health care team. There are several things we can do to get started. We can review organism pathogenicity and evaluate and question test results that may signal an unusual event or process that led to a disease. We can be alert to the epidemiologic potential of organism isolates from patients as they may apply to infection control or community epidemiology. We can become familiar with the zoonotic diseases and recognize the etiologic agents associated with wild and domestic animals and apply that knowledge to our diagnostic skills. As we further understand the "big picture" of One Health, we can ask strategic questions that can lead us to provide further technical assistance to facilitate earlier interventions that lead to positive patient outcomes and ultimately healthier populations. In human medicine, we generally work with one species of animal. Veterinarians work with all the rest. It is time to communicate with and learn from our veterinary clinical microbiology colleagues and begin to understand the critical nature of the human, animal, and environment interface. This is our opportunity to be at the front of this line and not stand on the sidelines watching. JF - Clinical Microbiology Newsletter AU - Miller, JMichael AD - National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, jmm8@cdc.gov Y1 - 2010/04/01/ PY - 2010 DA - 2010 Apr 01 SP - 51 EP - 56 PB - Elsevier Science, Box 882 New York NY 10159 USA VL - 32 IS - 7 SN - 0196-4399, 0196-4399 KW - Microbiology Abstracts A: Industrial & Applied Microbiology KW - Convergence KW - Domestic animals KW - A 01450:Environmental Pollution & Waste Treatment UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/746078297?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+Microbiology+Newsletter&rft.atitle=Implications+of+the+One+Health+Paradigm+for+Clinical+Microbiology&rft.au=Miller%2C+JMichael&rft.aulast=Miller&rft.aufirst=JMichael&rft.date=2010-04-01&rft.volume=32&rft.issue=7&rft.spage=51&rft.isbn=&rft.btitle=&rft.title=Clinical+Microbiology+Newsletter&rft.issn=01964399&rft_id=info:doi/10.1016%2Fj.clinmicnews.2010.03.003 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Domestic animals DO - http://dx.doi.org/10.1016/j.clinmicnews.2010.03.003 ER - TY - JOUR T1 - Diabetes Risk Reduction Behaviors Among U.S. Adults with Prediabetes AN - 746008951; 13043024 AB - Diabetes can be prevented or delayed in high-risk adults through lifestyle modifications, including dietary changes, moderate-intensity exercise, and modest weight loss. However, the extent to which U.S. adults with prediabetes are making lifestyle changes consistent with reducing risk is unknown. Purpose - This study aimed to study lifestyle changes consistent with reducing diabetes risk and factors associated with their adoption among adults with prediabetes. Methods - In 2009, data were analyzed from 1402 adults aged >=20 years without diabetes who participated in the 2005-2006 National Health and Nutrition Examination Survey and had valid fasting plasma glucose and oral glucose tolerance tests. The extent to which adults with prediabetes report that in the past year they tried to control or lose weight, reduced the amount of fat or calories in their diet, or increased physical activity or exercise was estimated and factors associated with the adoption of these behaviors were examined. Results - Almost 30% of the U.S. adult population had prediabetes in 2005-2006, but only 7.3% (95% CI=5.5%, 9.2%) were aware they had it. About half of adults with prediabetes reported performing diabetes risk reduction behaviors in the past year, but only about one third of adults with prediabetes had received healthcare provider advice about these behaviors in the past year. In multivariate analyses, provider advice, female gender, and being overweight or obese were positively associated with all three risk reduction behaviors. Conclusions - Adoption of risk reduction behaviors among U.S. adults with prediabetes is suboptimal. Efforts to improve awareness of prediabetes, increase promotion of healthy behaviors, and improve availability of evidence-based lifestyle programs are needed to slow the growth in new cases of diabetes. JF - American Journal of Preventive Medicine AU - Geiss, Linda S AU - James, Cherie AU - Gregg, Edward W AU - Albright, Ann AU - Williamson, David F AU - Cowie, Catherine C AD - Division of Diabetes Translation, CDC, Atlanta, Georgia, lgeiss@cdc.gov Y1 - 2010/04// PY - 2010 DA - Apr 2010 SP - 403 EP - 409 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 38 IS - 4 SN - 0749-3797, 0749-3797 KW - Risk Abstracts KW - Diets KW - risk reduction KW - USA KW - diabetes mellitus KW - Behavior KW - Gender KW - obesity KW - physical activity KW - Nutrition KW - Medical personnel KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/746008951?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Diabetes+Risk+Reduction+Behaviors+Among+U.S.+Adults+with+Prediabetes&rft.au=Geiss%2C+Linda+S%3BJames%2C+Cherie%3BGregg%2C+Edward+W%3BAlbright%2C+Ann%3BWilliamson%2C+David+F%3BCowie%2C+Catherine+C&rft.aulast=Geiss&rft.aufirst=Linda&rft.date=2010-04-01&rft.volume=38&rft.issue=4&rft.spage=403&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2009.12.029 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Diets; risk reduction; diabetes mellitus; Behavior; Gender; obesity; physical activity; Nutrition; Medical personnel; USA DO - http://dx.doi.org/10.1016/j.amepre.2009.12.029 ER - TY - JOUR T1 - Epidemiology of Seafood-Associated Infections in the United States AN - 745977716; 12676304 AB - Summary: Seafood is part of a healthful diet, but seafood consumption is not risk-free. Seafood is responsible for an important proportion of food-borne illnesses and outbreaks in the United States. Seafood-associated infections are caused by a variety of bacteria, viruses, and parasites; this diverse group of pathogens results in a wide variety of clinical syndromes, each with its own epidemiology. Some seafood commodities are inherently more risky than others, owing to many factors, including the nature of the environment from which they come, their mode of feeding, the season during which they are harvested, and how they are prepared and served. Prevention of seafood-associated infections requires an understanding not only of the etiologic agents and seafood commodities associated with illness but also of the mechanisms of contamination that are amenable to control. Defining these problem areas, which relies on surveillance of seafood-associated infections through outbreak and case reporting, can lead to targeted research and help to guide control efforts. Coordinated efforts are necessary to further reduce the risk of seafood-associated illnesses. Continued surveillance will be important to assess the effectiveness of current and future prevention strategies. JF - Clinical Microbiology Reviews AU - Iwamoto, Martha AU - Ayers, Tracy AU - Mahon, Barbara E AU - Swerdlow, David L AD - Centers for Disease Control and Prevention, Atlanta, Georgia, miwamoto@cdc.gov PY - 2010 SP - 399 EP - 411 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 23 IS - 2 SN - 0893-8512, 0893-8512 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts KW - Diets KW - Feeding KW - Parasites KW - Epidemiology KW - Contamination KW - Food KW - Seafood KW - Pathogens KW - Infection KW - V 22490:Miscellaneous KW - A 01330:Food Microbiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745977716?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+Microbiology+Reviews&rft.atitle=Epidemiology+of+Seafood-Associated+Infections+in+the+United+States&rft.au=Iwamoto%2C+Martha%3BAyers%2C+Tracy%3BMahon%2C+Barbara+E%3BSwerdlow%2C+David+L&rft.aulast=Iwamoto&rft.aufirst=Martha&rft.date=2010-04-01&rft.volume=23&rft.issue=2&rft.spage=399&rft.isbn=&rft.btitle=&rft.title=Clinical+Microbiology+Reviews&rft.issn=08938512&rft_id=info:doi/10.1128%2FCMR.00059-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-01 N1 - Number of references - 70 N1 - Last updated - 2016-01-06 N1 - SubjectsTermNotLitGenreText - Diets; Parasites; Feeding; Contamination; Epidemiology; Food; Pathogens; Seafood; Infection DO - http://dx.doi.org/10.1128/CMR.00059-09 ER - TY - JOUR T1 - Sickle Cell Disease -- Related Pediatric Medical Expenditures in the U.S. AN - 742956615; 2010-508684 AB - Background: Although it is known that people with sickle cell disease (SCD) have relatively high utilization of medical care, most previous estimates of SCD-attributable expenditures have been limited to either inpatient care or single-state data. Purpose: To extend known findings by measuring the attributable or incremental expenditures per child with SCD compared to children without this illness & to thereby estimate SCD-attributable expenditures among children in the U.S. Methods: MarketScan Medicaid & Commercial Claims databases for 2005 were used to estimate total medical expenditures of children with & without SCD. Expenditures attributable to SCD were calculated as the difference in age-adjusted mean expenditures during 2005 for children with SCD relative to children without SCD in the two databases. Results: Children with SCD incurred medical expenditures that were $9369 & $13,469 higher than those of children without SCD enrolled in Medicaid & private insurance, respectively. In other words, expenditures of children with SCD were 6 & 11 times those of children without SCD enrolled in Medicaid & private insurance, respectively. Conclusions: Using a large, multistate, multipayer patient sample, SCD-attributable medical expenditures in children were conservatively & approximately estimated at $335 million in 2005. Adapted from the source document. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Amendah, Djesika D AU - Mvundura, Mercy AU - Kavanagh, Patricia L AU - Sprinz, Philippa G AU - Grosse, Scott D AD - Div Blood Disorders, National Center Birth Defects Developmental Disabilities, CDC, Atlanta damendah@cdc.gov Y1 - 2010/04// PY - 2010 DA - April 2010 SP - S550 EP - S556 PB - Elsevier Science, New York NY VL - 38 IS - S4 SN - 0749-3797, 0749-3797 KW - Health conditions and policy - Diseases and disorders KW - Health conditions and policy - Health and health policy KW - Economic conditions and policy - Economic theory KW - Cost KW - United States KW - Patients KW - Diseases KW - Child health KW - Sickle cell anemia KW - Public health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742956615?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Sickle+Cell+Disease+--+Related+Pediatric+Medical+Expenditures+in+the+U.S.&rft.au=Amendah%2C+Djesika+D%3BMvundura%2C+Mercy%3BKavanagh%2C+Patricia+L%3BSprinz%2C+Philippa+G%3BGrosse%2C+Scott+D&rft.aulast=Amendah&rft.aufirst=Djesika&rft.date=2010-04-01&rft.volume=38&rft.issue=S4&rft.spage=S550&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2010.01.004 LA - English DB - PAIS Index N1 - Date revised - 2010-06-07 N1 - Last updated - 2016-09-28 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Sickle cell anemia; United States; Public health; Cost; Child health; Patients; Diseases DO - http://dx.doi.org/10.1016/j.amepre.2010.01.004 ER - TY - JOUR T1 - The Impact of Immigration Status on Tobacco Use among Chinese-American Adults in Texas AN - 742717177; 201010291 AB - Abstract Objectives This study analyzed the impact of immigration status on current tobacco use among adult Chinese-Americans living in Texas. Methods A survey was administered in Chinese and English in 2004 to assess tobacco use among Chinese-American adults using a stratified probability sample from two large metropolitan areas in Texas. Data were adjusted for unequal probability of selection and weighted to provide state-wide estimates for Chinese-Americans in Texas. Results The study sample was comprised of 1,054 Chinese-American adults. The overall current smoking rate was 11.1% with men's rates much higher (16.1%) than women's (6.7%). Lower household income and education increased smoking among males but more educated females had a tendency to smoke more. Although overall smoking rate among Chinese-Americans was significantly lower than the general Texas population (20.6%), smoking rate among recent immigrant men (<5 years in the U.S.) was alarmingly higher (28.0%). U.S.-born Chinese-American men's smoking rate (25.0%) is similar to that of their U.S.-born counterparts (23.7%). U.S.-born Chinese-American men initiated smoking 4 years earlier (13.8 years) than their immigrant counterparts. Conclusions Although Chinese-Americans in Texas had overall lower smoking rates than the general population, the high smoking rates among recently immigrated men emphasize the need for cessation activities targeting this group. Adapted from the source document. JF - Journal of Immigrant and Minority Health AU - Hu, Shaohua S AU - Pallonen, Unto E AU - Meshack, Angela F AD - Division of Adult and Community Health, Center for Disease Control and Prevention, 4770 Buford Highway NE, MS: K-66, Atlanta, GA 30341-3717, USA shu@cdc.gov Y1 - 2010/04// PY - 2010 DA - April 2010 SP - 206 EP - 214 PB - Springer, Dordrecht The Netherlands VL - 12 IS - 2 SN - 1557-1912, 1557-1912 KW - Smoking KW - Immigration KW - Chinese American people KW - Men KW - Cessation KW - Immigrants KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742717177?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Immigrant+and+Minority+Health&rft.atitle=The+Impact+of+Immigration+Status+on+Tobacco+Use+among+Chinese-American+Adults+in+Texas&rft.au=Hu%2C+Shaohua+S%3BPallonen%2C+Unto+E%3BMeshack%2C+Angela+F&rft.aulast=Hu&rft.aufirst=Shaohua&rft.date=2010-04-01&rft.volume=12&rft.issue=2&rft.spage=206&rft.isbn=&rft.btitle=&rft.title=Journal+of+Immigrant+and+Minority+Health&rft.issn=15571912&rft_id=info:doi/10.1007%2Fs10903-007-9097-z LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-10-21 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Smoking; Chinese American people; Men; Immigrants; Immigration; Cessation DO - http://dx.doi.org/10.1007/s10903-007-9097-z ER - TY - JOUR T1 - Leveraging Geospatial Data, Technology, and Methods for Improving the Health of Communities: Priorities and Strategies from an Expert Panel Convened by the CDC AN - 58843785; 2010-499794 AB - In 2008, CDC convened an expert panel to gather input on the use of geospatial science in surveillance, research and program activities focused on CDC's Healthy Communities Goal. The panel suggested six priorities: spatially enable and strengthen public health surveillance infrastructure; develop metrics for geospatial categorization of community health and health inequity; evaluate the feasibility and validity of standard metrics of community health and health inequities; support and develop GIScience and geospatial analysis; provide geospatial capacity building, training and education; and, engage non-traditional partners. Following the meeting, the strategies and action items suggested by the expert panel were reviewed by a CDC subcommittee to determine priorities relative to ongoing CDC geospatial activities, recognizing that many activities may need to occur either in parallel, or occur multiple times across phases. Phase A of the action items centers on developing leadership support. Phase B focuses on developing internal and external capacity in both physical (e.g., software and hardware) and intellectual infrastructure. Phase C of the action items plan concerns the development and integration of geospatial methods. In summary, the panel members provided critical input to the development of CDC's strategic thinking on integrating geospatial methods and research issues across program efforts in support of its Healthy Communities Goal. Adapted from the source document. JF - Journal of Community Health AU - Elmore, Kim AU - Flanagan, Barry AU - Jones, Nicholas F AU - Heitgerd, Janet L AD - CDC/Division of HIV/AIDS Prevention, 1600 Clifton Rd. NE, MS E-48, Atlanta, GA, 30333, USA kelmore@cdc.gov Y1 - 2010/04// PY - 2010 DA - April 2010 SP - 165 EP - 171 PB - Springer, New York NY VL - 35 IS - 2 SN - 0094-5145, 0094-5145 KW - Health conditions and policy - Health and health policy KW - Law and ethics - Criminal law KW - Government - Internal security KW - Economic conditions and policy - Economic policy, planning, and development KW - Politics - Politics and policy-making KW - Infrastructure KW - Standards KW - United States Centers for disease control and prevention KW - Leadership KW - Surveillance KW - Public health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58843785?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Community+Health&rft.atitle=Leveraging+Geospatial+Data%2C+Technology%2C+and+Methods+for+Improving+the+Health+of+Communities%3A+Priorities+and+Strategies+from+an+Expert+Panel+Convened+by+the+CDC&rft.au=Elmore%2C+Kim%3BFlanagan%2C+Barry%3BJones%2C+Nicholas+F%3BHeitgerd%2C+Janet+L&rft.aulast=Elmore&rft.aufirst=Kim&rft.date=2010-04-01&rft.volume=35&rft.issue=2&rft.spage=165&rft.isbn=&rft.btitle=&rft.title=Journal+of+Community+Health&rft.issn=00945145&rft_id=info:doi/10.1007%2Fs10900-009-9210-4 LA - English DB - PAIS Index N1 - Date revised - 2010-10-21 N1 - Last updated - 2016-09-28 N1 - CODEN - JCMHBR N1 - SubjectsTermNotLitGenreText - Public health; United States Centers for disease control and prevention; Surveillance; Infrastructure; Leadership; Standards DO - http://dx.doi.org/10.1007/s10900-009-9210-4 ER - TY - CPAPER T1 - Biology of H1N1 Infection T2 - 2010 Gordon Research Conference on Biology Of Acute Respiratory Infection AN - 742791471; 5675205 JF - 2010 Gordon Research Conference on Biology Of Acute Respiratory Infection AU - Tumpey, Terrence Y1 - 2010/03/21/ PY - 2010 DA - 2010 Mar 21 KW - Infection KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742791471?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2010+Gordon+Research+Conference+on+Biology+Of+Acute+Respiratory+Infection&rft.atitle=Biology+of+H1N1+Infection&rft.au=Tumpey%2C+Terrence&rft.aulast=Tumpey&rft.aufirst=Terrence&rft.date=2010-03-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2010+Gordon+Research+Conference+on+Biology+Of+Acute+Respiratory+Infection&rft.issn=&rft_id=info:doi/ L2 - http://www.grc.org/programs.aspx?year=2010&program=acuteresp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-17 N1 - Last updated - 2010-08-14 ER - TY - CPAPER T1 - Traumatic brain injury in the United States: National estimates of prevalence and incidence, 2002-2006. T2 - Eighth World Congress on Brain Injury AN - 742820947; 5699881 JF - Eighth World Congress on Brain Injury AU - Coronado, Victor AU - Wald, Marlena AU - Faul, Mark AU - Xu, Likang Y1 - 2010/03/10/ PY - 2010 DA - 2010 Mar 10 KW - USA KW - Brain KW - Traumatic brain injury KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742820947?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Eighth+World+Congress+on+Brain+Injury&rft.atitle=Traumatic+brain+injury+in+the+United+States%3A+National+estimates+of+prevalence+and+incidence%2C+2002-2006.&rft.au=Coronado%2C+Victor%3BWald%2C+Marlena%3BFaul%2C+Mark%3BXu%2C+Likang&rft.aulast=Coronado&rft.aufirst=Victor&rft.date=2010-03-10&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Eighth+World+Congress+on+Brain+Injury&rft.issn=&rft_id=info:doi/ L2 - https://ibia.conference-services.net/programme.asp?conferenceID=1677&l LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-17 N1 - Last updated - 2010-08-14 ER - TY - JOUR T1 - Mouse pulmonary dose- and time course-responses induced by exposure to multi-walled carbon nanotubes. AN - 733805511; 19857541 AB - Carbon nanotubes (CNT) come in a variety of types, but one of the most common forms is multi-walled carbon nanotubes (MWCNT). MWCNT have potential applications in many diverse commercial processes, and thus human exposures are considered to be likely. In order to investigate the pulmonary toxicity of MWCNT, we conducted an in vivo dose-response and time course study of MWCNT in mice in order to assess their ability to induce pulmonary inflammation, damage, and fibrosis using doses that approximate estimated human occupational exposures. MWCNT were dispersed in dispersion medium (DM) and male C57BL/6J mice (7 weeks old) received either DM (vehicle control), 10, 20, 40 or 80mug MWCNT by aspiration exposure. At 1, 7, 28 and 56 days post-exposure, MWCNT-induced pulmonary toxicity was investigated. Bronchoalveolar lavage (BAL) studies determined pulmonary inflammation and damage was dose-dependent and peaked at 7 days post-exposure. By 56 days post-exposure, pulmonary inflammation and damage markers were returning to control levels, except for the 40mug MWCNT dose, which was still significantly higher than vehicle control. Histopathological studies determined that MWCNT exposure caused rapid development of pulmonary fibrosis by 7 days post-exposure, that granulomatous inflammation persisted throughout the 56-day post-exposure period, and also demonstrated that MWCNT can reach the pleura after pulmonary exposure. In summary, the data reported here indicate that MWCNT exposure rapidly produces significant adverse health outcomes in the lung. Furthermore, the observation that MWCNT reach the pleura after aspiration exposure indicates that more extensive investigations are needed to fully assess if pleural penetration results in any adverse health outcomes. JF - Toxicology AU - Porter, Dale W AU - Hubbs, Ann F AU - Mercer, Robert R AU - Wu, Nianqiang AU - Wolfarth, Michael G AU - Sriram, Krishnan AU - Leonard, Stephen AU - Battelli, Lori AU - Schwegler-Berry, Diane AU - Friend, Sherry AU - Andrew, Michael AU - Chen, Bean T AU - Tsuruoka, Shuji AU - Endo, Morinobu AU - Castranova, Vincent AD - National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA. DPorter@cdc.gov Y1 - 2010/03/10/ PY - 2010 DA - 2010 Mar 10 SP - 136 EP - 147 VL - 269 IS - 2-3 KW - Nanotubes, Carbon KW - 0 KW - Index Medicus KW - Animals KW - Dose-Response Relationship, Drug KW - Toxicity Tests KW - Mice, Inbred C57BL KW - Mice KW - Bronchoalveolar Lavage Fluid -- cytology KW - Male KW - Pneumonia -- chemically induced KW - Nanotubes, Carbon -- chemistry KW - Inhalation Exposure -- analysis KW - Nanotubes, Carbon -- ultrastructure KW - Lung -- ultrastructure KW - Lung -- drug effects KW - Lung -- pathology KW - Nanotubes, Carbon -- toxicity KW - Pneumonia -- pathology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733805511?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology&rft.atitle=Mouse+pulmonary+dose-+and+time+course-responses+induced+by+exposure+to+multi-walled+carbon+nanotubes.&rft.au=Porter%2C+Dale+W%3BHubbs%2C+Ann+F%3BMercer%2C+Robert+R%3BWu%2C+Nianqiang%3BWolfarth%2C+Michael+G%3BSriram%2C+Krishnan%3BLeonard%2C+Stephen%3BBattelli%2C+Lori%3BSchwegler-Berry%2C+Diane%3BFriend%2C+Sherry%3BAndrew%2C+Michael%3BChen%2C+Bean+T%3BTsuruoka%2C+Shuji%3BEndo%2C+Morinobu%3BCastranova%2C+Vincent&rft.aulast=Porter&rft.aufirst=Dale&rft.date=2010-03-10&rft.volume=269&rft.issue=2-3&rft.spage=136&rft.isbn=&rft.btitle=&rft.title=Toxicology&rft.issn=1879-3185&rft_id=info:doi/10.1016%2Fj.tox.2009.10.017 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-04-09 N1 - Date created - 2010-03-24 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.tox.2009.10.017 ER - TY - CPAPER T1 - Analysis of first cluster outbreak of the pandemic influenza (H1N1) in Georgia T2 - 14th International Congress on Infectious Diseases (ICID 2010) AN - 742808907; 5700403 JF - 14th International Congress on Infectious Diseases (ICID 2010) AU - Zakhashvili, K AU - Imnadze, P AU - Tarkhan-Mouravi, O Y1 - 2010/03/09/ PY - 2010 DA - 2010 Mar 09 KW - USA, Georgia KW - Outbreaks KW - Influenza KW - Pandemics KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742808907?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=unknown&rft.jtitle=Education+Daily&rft.atitle=Study+tracks+2013+grads%27+college+enrollment%2C+persistence&rft.au=Gossman%2C+Jean&rft.aulast=Gossman&rft.aufirst=Jean&rft.date=2014-10-17&rft.volume=47&rft.issue=179&rft.spage=3&rft.isbn=&rft.btitle=&rft.title=Education+Daily&rft.issn=00131261&rft_id=info:doi/ L2 - http://www.x-cd.com/isidmain2010/program.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-17 N1 - Last updated - 2010-08-14 ER - TY - JOUR T1 - Limited Evolution of Human Immunodeficiency Virus Type 1 in the Thymus of a Perinatally Infected Child AN - 754543614; 13269933 AB - Background. Involvement of the thymus during human immunodeficiency virus (HIV) infection may impair production of naive lymphocytes leading to more rapid depletion, but the characteristics of primary strains in the thymus are not well studied because of the unavailability of tissue in living individuals. Methods. We studied the characteristics of HIV type 1 (HIV-1) in a 5-year old perinatally infected child with thymitis and compared the genomic sequences of the HIV-1 C2-V5 region of the env gene in the thymic tissue and peripheral blood. Results. The thymus harbored predominantly viral sequences close to the founder HIV-1 variant that circulated in the blood at 2 and 3 months of age, whereas the peripheral blood virus at 5 years of age had evolved extensively. Viral sequences from circulating CD8 super(+) T cells at 5 years of age phylogenetically clustered with those from the thymoc tissue. Conclusions. These results indicate the existence of a distinct thymic viral reservoir and suggest that circulating CD8 super(+) T cells were infected in the thymus, presumably at the CD4 super(+)CD8 super(+) thymocyte stage. They also demonstrate that not all thymic HIV infections will necessarily lead to severe thymic dysfunction. The characteristics of the virus strain seeding the thymus may dictate the rate of disease progression. JF - Clinical Infectious Diseases AU - Scinicariello, F AU - Kourtis AU - Nesheim, S AU - Abramowsky, C AU - Lee, F K AD - Div of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, MS-K34, 4770 Buford Hwy, NE, Atlanta, GA 30341, USA, apk3@cdc.gov Y1 - 2010/03/01/ PY - 2010 DA - 2010 Mar 01 SP - 726 EP - 732 VL - 50 IS - 5 SN - 1058-4838, 1058-4838 KW - Immunology Abstracts; Health & Safety Science Abstracts; Virology & AIDS Abstracts KW - Phylogeny KW - Age KW - Thymus KW - Peripheral blood KW - Env protein KW - Lymphocytes KW - CD8 antigen KW - Infection KW - seeding KW - CD4 antigen KW - Human immunodeficiency virus KW - Human immunodeficiency virus 1 KW - infection KW - Lymphocytes T KW - Thymocytes KW - genomics KW - Reservoirs KW - Evolution KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - V 22360:AIDS and HIV KW - F 06910:Microorganisms & Parasites UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754543614?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+Infectious+Diseases&rft.atitle=Limited+Evolution+of+Human+Immunodeficiency+Virus+Type+1+in+the+Thymus+of+a+Perinatally+Infected+Child&rft.au=Scinicariello%2C+F%3BKourtis%3BNesheim%2C+S%3BAbramowsky%2C+C%3BLee%2C+F+K&rft.aulast=Scinicariello&rft.aufirst=F&rft.date=2010-03-01&rft.volume=50&rft.issue=5&rft.spage=726&rft.isbn=&rft.btitle=&rft.title=Clinical+Infectious+Diseases&rft.issn=10584838&rft_id=info:doi/10.1086%2F650453 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Phylogeny; CD4 antigen; Age; Thymus; Lymphocytes T; Thymocytes; Env protein; Peripheral blood; genomics; CD8 antigen; Infection; Evolution; seeding; Human immunodeficiency virus; infection; Lymphocytes; Reservoirs; Human immunodeficiency virus 1 DO - http://dx.doi.org/10.1086/650453 ER - TY - JOUR T1 - Association of Paternal Age and Risk for Major Congenital Anomalies From the National Birth Defects Prevention Study, 1997 to 2004 AN - 745706240; 12966392 AB - Purpose - The objective of this study was to examine the associations between paternal age and birth defects of unknown etiologies while carefully controlling for maternal age. Methods - By using 1997 to 2004 data from the National Birth Defects Prevention Study, we fit logistic regression models with paternal and maternal age as continuous variables while adjusting for demographic and other factors. Results - Elevated odds ratios (ORs) for each year increase in paternal age were found for cleft palate (OR. 1.02, 95% confidence interval [95% CI], 1.00-1.04), diaphragmatic hernia (OR, 1.04; 95% CI, 1.02-1.06), right ventricular outflow tract obstruction (OR, 1.03; 95% CI, 1.01-1.04), and pulmonary valve stenosis (OR, 1.02, 95% CI, 1.01-1.04). At younger paternal ages, each year increase in paternal age correlated with increased odds of having offspring with encephalocele, cataract, esophageal atresia, anomalous pulmonary venous return, and coarctation of the aorta, but these increased odds were not observed at older paternal ages. The effect of paternal age was modified by maternal age for gastroschisis, omphalocele, spina bifida, all orofacial clefts, and septal heart defects. Conclusions - Our findings suggest that paternal age may be a risk factor for some multifactorial birth defects. JF - Annals of Epidemiology AU - Green, Ridgely Fisk AU - Devine, Owen AU - Crider, Krista S AU - Olney, Richard S AU - Archer, Natalie AU - Olshan, Andrew F AU - Shapira, Stuart K AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA, grf1@cdc.gov Y1 - 2010/03// PY - 2010 DA - Mar 2010 SP - 241 EP - 249 PB - Elsevier Science, Box 882 New York NY 10159 USA VL - 20 IS - 3 SN - 1047-2797, 1047-2797 KW - Risk Abstracts KW - Congenital Abnormalities KW - Maternal Age KW - Paternal Age KW - Risk Factors KW - demography KW - Age KW - Etiology KW - cataracts KW - prevention KW - Congenital defects KW - outflow KW - spina bifida KW - offspring KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745706240?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annals+of+Epidemiology&rft.atitle=Association+of+Paternal+Age+and+Risk+for+Major+Congenital+Anomalies+From+the+National+Birth+Defects+Prevention+Study%2C+1997+to+2004&rft.au=Green%2C+Ridgely+Fisk%3BDevine%2C+Owen%3BCrider%2C+Krista+S%3BOlney%2C+Richard+S%3BArcher%2C+Natalie%3BOlshan%2C+Andrew+F%3BShapira%2C+Stuart+K&rft.aulast=Green&rft.aufirst=Ridgely&rft.date=2010-03-01&rft.volume=20&rft.issue=3&rft.spage=241&rft.isbn=&rft.btitle=&rft.title=Annals+of+Epidemiology&rft.issn=10472797&rft_id=info:doi/10.1016%2Fj.annepidem.2009.10.009 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - demography; Etiology; Age; cataracts; prevention; spina bifida; outflow; Congenital defects; offspring DO - http://dx.doi.org/10.1016/j.annepidem.2009.10.009 ER - TY - JOUR T1 - Lifestyle behaviors and receipt of preventive health care services among hypertensive Americans aged 45 years or older in 2007 AN - 745636332; 12965737 AB - Objective. - The aim of the study was to explore opportunities for more effective interventions on lifestyle modifications among hypertensives. Methods. - Using 2007 data from the Behavioral Risk Factor Surveillance System from the United States, we assessed the prevalence of various lifestyle behaviors and receipt of preventive health care services among US adults aged 45 years or older based on hypertension and treatment status (n = 218,228). Results. - Compared with nonhypertensives, hypertensives were significantly less likely to engage in recommended levels of physical activity and to be more obese regardless of treatment status. Compared to nonhypertensives, hypertensives on medical treatment were less likely to consume five or more servings of fruit and vegetables per day, be current smokers, and binge drinkers. Hypertensives not on medical treatment were more likely to be current smokers, binge and heavy drinkers. Hypertensives on medical treatment were more likely to have routine health checkup, have blood cholesterol checkup within previous 5 years and have a flu shot within the previous year than hypertensives not on treatment. Conclusion. - Different patterns of lifestyle behaviors and use of preventive health care services were found based on treatment status among hypertensives. Intervention programs should be tailored accordingly to achieve optimal outcome on lifestyle modification. JF - Preventive Medicine AU - Fan, Amy Z AU - Mallawaarachchi, Dona Stephnie Virginie AU - Gilbertz, David AU - Li, Yan AU - Mokdad, Ali H AD - Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, USA, afan@cdc.gov Y1 - 2010/03// PY - 2010 DA - Mar 2010 SP - 138 EP - 142 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 50 IS - 3 SN - 0091-7435, 0091-7435 KW - Health & Safety Science Abstracts; Risk Abstracts KW - obesity KW - binge drinking KW - cholesterol KW - USA KW - Health care KW - Behavior KW - intervention KW - hypertension KW - Medical treatment KW - physical activity KW - H 12000:Epidemiology and Public Health KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745636332?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Preventive+Medicine&rft.atitle=Lifestyle+behaviors+and+receipt+of+preventive+health+care+services+among+hypertensive+Americans+aged+45+years+or+older+in+2007&rft.au=Fan%2C+Amy+Z%3BMallawaarachchi%2C+Dona+Stephnie+Virginie%3BGilbertz%2C+David%3BLi%2C+Yan%3BMokdad%2C+Ali+H&rft.aulast=Fan&rft.aufirst=Amy&rft.date=2010-03-01&rft.volume=50&rft.issue=3&rft.spage=138&rft.isbn=&rft.btitle=&rft.title=Preventive+Medicine&rft.issn=00917435&rft_id=info:doi/10.1016%2Fj.ypmed.2009.12.007 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Behavior; Health care; intervention; hypertension; obesity; Medical treatment; physical activity; cholesterol; binge drinking; USA DO - http://dx.doi.org/10.1016/j.ypmed.2009.12.007 ER - TY - JOUR T1 - Physical Violence Against U.S. Women Around the Time of Pregnancy, 2004-2007 AN - 744693667; 12966697 AB - Previous research shows that the prevalence of intimate partner violence (IPV) around the time of pregnancy varies from 4% to 9%, but no studies have distinguished between abuse rates by former versus current partners. Purpose - This study aims to estimate the prevalence of IPV among U.S. women shortly before and during pregnancy and to compare the rates and predictors of abuse perpetrated by current partners with the rates and predictors of abuse perpetrated by former partners. Methods - Using data from 27 states and New York City, the prevalence of physical abuse by current and former intimate male partners was estimated among 134,955 women who delivered a singleton, full-term infant in 2004-2007. Multivariable logistic regression was used to determine the demographic, pregnancy-related, and stress factors that predicted the risk of IPV. Results - Prevalence of IPV from either a former or current partner was 5.3% before and 3.6% during pregnancy. Prevalence of abuse by a former partner was consistently higher than the prevalence of abuse by a current partner. The three strongest predictors of IPV during pregnancy were the woman's partner not wanting the pregnancy (current: AOR=3.47, 95% CI=3.13, 3.85; former: AOR=3.22, 95% CI=2.90, 3.76); having had a recent divorce or separation (current: AOR=3.23, 95% CI=2.92, 3.58; former: AOR=3.54, 95% CI=3.20, 3.91); and being close to someone having a drug or alcohol problem (current: AOR=3.05, 95% CI=2.78, 3.36; former: AOR=2.97, 95% CI=2.70, 3.27). Maternal characteristics (age, education, race, marital status, woman did not want the pregnancy) were less important predictors. Conclusions - Assessments of abuse should ask specifically about actions by both current and ex-partners. JF - American Journal of Preventive Medicine AU - Chu, Susan Y AU - Goodwin, Mary M AU - D'Angelo, Denise V AD - Division of Reproductive Health, CDC, Atlanta, Georgia, syc1@cdc.gov Y1 - 2010/03// PY - 2010 DA - Mar 2010 SP - 317 EP - 322 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 38 IS - 3 SN - 0749-3797, 0749-3797 KW - Risk Abstracts; Health & Safety Science Abstracts KW - demography KW - Alcohol KW - Age KW - Stress KW - domestic violence KW - marriage KW - Violence KW - Pregnancy KW - USA, New York, New York City KW - Education KW - Females KW - Drugs KW - Urban areas KW - Infants KW - H 11000:Diseases/Injuries/Trauma KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/744693667?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Physical+Violence+Against+U.S.+Women+Around+the+Time+of+Pregnancy%2C+2004-2007&rft.au=Chu%2C+Susan+Y%3BGoodwin%2C+Mary+M%3BD%27Angelo%2C+Denise+V&rft.aulast=Chu&rft.aufirst=Susan&rft.date=2010-03-01&rft.volume=38&rft.issue=3&rft.spage=317&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2009.11.013 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - demography; Alcohol; Age; domestic violence; Stress; marriage; Violence; Pregnancy; Education; Females; Drugs; Infants; Urban areas; USA, New York, New York City DO - http://dx.doi.org/10.1016/j.amepre.2009.11.013 ER - TY - JOUR T1 - Evaluation of the Centers for Disease Control and Prevention's Concussion Initiative for High School Coaches: 'Heads Up: Concussion in High School Sports' AN - 744614040; 12774234 AB - BACKGROUND: To reduce the number of sports-related concussions, the Centers for Disease Control and Prevention (CDC), with the support of partners and experts in the field, has developed a tool kit for high school coaches with practical, easy-to-use concussion-related information. This study explores the success of the tool kit in changing knowledge, attitudes, and practices related to the prevention and management of concussions.METHODS: A mail questionnaire was administered to all eligible high school coaches who received the tool kit. Follow-up focus groups were conducted for additional information. Both quantitative data from the surveys and qualitative data from the focus groups were analyzed to support the objectives of the study.RESULTS: Respondents self-reported favorable changes in knowledge, attitudes, and practices toward the prevention and management of concussions. Qualitative responses augmented the quantitative data.CONCLUSION: Barriers to concussion prevention and management are complex; however, these results highlight the role that coaches can play in school settings in establishing a safe environment for their athletes. JF - Journal of School Health AU - Sarmiento, Kelly AU - Mitchko, Jane AU - Klein, Cynthia AU - Wong, Sharon AD - aHealth Communications Specialist, Centers for Disease Control and Prevention/National Center for Injury Prevention and Control-Division of Injury Response, 4770 Buford Hwy, NE, Mail Stop F-62, Atlanta, GA 30341, KSarmiento@cdc.gov Y1 - 2010/03// PY - 2010 DA - Mar 2010 SP - 112 EP - 118 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 USA VL - 80 IS - 3 SN - 0022-4391, 0022-4391 KW - Physical Education Index; Health & Safety Science Abstracts KW - Management KW - Preventive health KW - head injuries KW - Surveys KW - Concussion KW - disease control KW - attitudes KW - athletes KW - Interscholastic sports KW - High schools KW - Attitudes KW - schools KW - Coaches KW - prevention KW - Diseases KW - Environment management KW - H 11000:Diseases/Injuries/Trauma KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/744614040?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+School+Health&rft.atitle=Evaluation+of+the+Centers+for+Disease+Control+and+Prevention%27s+Concussion+Initiative+for+High+School+Coaches%3A+%27Heads+Up%3A+Concussion+in+High+School+Sports%27&rft.au=Sarmiento%2C+Kelly%3BMitchko%2C+Jane%3BKlein%2C+Cynthia%3BWong%2C+Sharon&rft.aulast=Sarmiento&rft.aufirst=Kelly&rft.date=2010-03-01&rft.volume=80&rft.issue=3&rft.spage=112&rft.isbn=&rft.btitle=&rft.title=Journal+of+School+Health&rft.issn=00224391&rft_id=info:doi/10.1111%2Fj.1746-1561.2010.00491.x LA - English DB - Physical Education Index; ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Number of references - 6 N1 - Last updated - 2014-05-02 N1 - SubjectsTermNotLitGenreText - Interscholastic sports; Attitudes; High schools; Management; Coaches; Preventive health; Surveys; Concussion; Diseases; athletes; schools; head injuries; prevention; disease control; Environment management; attitudes DO - http://dx.doi.org/10.1111/j.1746-1561.2010.00491.x ER - TY - JOUR T1 - Confidence as a Predictor of Sexual and Reproductive Health Outcomes for Youth AN - 742716593; 201009979 AB - Purpose To assess the association between four positive youth development (PYD) constructs of confidence and adolescent sexual and reproductive health (ASRH) outcomes. Methods We searched nine online databases to locate behavioral research that examined the association between four constructs of confidence (belief in the future, self-determination, clear and positive identity, and self-efficacy) and ASRH outcomes (e.g., ever had sex, condom use, contraception use, number of partners, pregnancy/birth, and sexually transmitted infection). Findings were coded as 'protective,' 'risk,' or 'no association.' The presence of at least two longitudinal studies reporting consistent significant associations for at least one ASRH outcome indicated evidence for a protective or risk association. Results We found evidence to support two of the four PYD constructs of confidence (belief in the future and self-determination) as protective factors for ASRH outcomes. Evidence was insufficient to draw conclusions about clear and positive identity as a protective factor, and was mixed for self-efficacy. Measures of confidence varied considerably across the studies reviewed, reflecting varying definitions; often, the measures used had limited information on reliability. Few longitudinal investigations were identified, and available studies were inconsistent in how they examined the association between the PYD constructs and ASRH outcomes. Evidence for most constructs was insufficient to identify their influence on specific sub-groups of youth. Conclusions Despite the need for additional research, this review suggests that belief in the future and self-determination are promising protective factors. Further research is needed to better understand the potential for self-efficacy and clear and positive identity as protective factors. [Copyright The Society for Adolescent Medicine; published by Elsevier Inc.] JF - Journal of Adolescent Health AU - Gloppen, Kari M AU - David-Ferdon, Corinne AU - Bates, Jessica AD - Division of Adolescent and School Health, CDC, Atlanta, Georgia kgloppen@cdc.gov Y1 - 2010/03// PY - 2010 DA - March 2010 SP - S42 EP - S58 PB - Elsevier, New York NY VL - 46 IS - 3S1 SN - 1054-139X, 1054-139X KW - Adolescent HIV prevention STD prevention Unintended pregnancy Youth development Confidence Belief in the future Self-efficacy Self-determination Identity KW - Selfefficacy KW - Protective factors KW - Identity KW - Health status KW - Reproductive health KW - Selfdetermination KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742716593?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Adolescent+Health&rft.atitle=Confidence+as+a+Predictor+of+Sexual+and+Reproductive+Health+Outcomes+for+Youth&rft.au=Gloppen%2C+Kari+M%3BDavid-Ferdon%2C+Corinne%3BBates%2C+Jessica&rft.aulast=Gloppen&rft.aufirst=Kari&rft.date=2010-03-01&rft.volume=46&rft.issue=3S1&rft.spage=S42&rft.isbn=&rft.btitle=&rft.title=Journal+of+Adolescent+Health&rft.issn=1054139X&rft_id=info:doi/10.1016%2Fj.jadohealth.2009.11.216 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-05-10 N1 - Last updated - 2016-09-27 N1 - CODEN - JAHCD9 N1 - SubjectsTermNotLitGenreText - Protective factors; Selfdetermination; Identity; Selfefficacy; Reproductive health; Health status DO - http://dx.doi.org/10.1016/j.jadohealth.2009.11.216 ER - TY - JOUR T1 - Condoms for Dual Protection: Patterns of Use with Highly Effective Contraceptive Methods AN - 58840740; 2010-490320 AB - Objectives. U.S. women experience high rates of unplanned pregnancy and sexually transmitted infections (STIs), yet they seldom combine condoms with highly effective contraceptives for optimal protection. Because oral contraceptives (OCs) have been the predominant form of highly effective contraception in the U.S., it is unknown whether condom use is similarly low with increasingly promoted user-independent methods. Methods. We used weighted data from the National Survey of Family Growth to assess condom use odds among women relying on OCs vs. user-independent methods (i.e., injectibles, intrauterine devices, and implants). We also estimated the expected reduction in unplanned pregnancies and abortions if half or all of the women currently using a single highly effective method also used condoms. Results. Across every demographic subgroup based on age, partner status, race/ethnicity, household income, and education, condom use prevalence was lower for women relying on user-independent methods vs. OCs. Multivariable models for adult women also revealed a significant reduction within most demographic subgroups in the odds of condom use among women relying on user-independent methods vs. OCs. Population estimates suggested that if half of all women using highly effective methods alone also used condoms, approximately 40% of unplanned pregnancies and abortions among these women could be prevented, for an annual reduction of 393,000 unplanned pregnancies and nearly 76,000 abortions. If all highly effective method users also used condoms, approximately 80% of unplanned pregnancies and abortions among these women could be prevented, for an annual reduction of 786,000 unplanned pregnancies and nearly 152,000 abortions. Conclusions. Adding condoms to other methods should be considered seriously as the first line of defense against unplanned pregnancy and STIs. This analysis can serve to target interventions where dual-method promotion is needed most. Adapted from the source document. JF - Public Health Reports AU - Pazol, Karen AU - Kramer, Michael R AU - Hogue, Carol J AD - Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Division of Reproductive Health, Maternal and Infant Health Branch, 477 Buford Hwy., MS-K21, Atlanta, GA 30341-3724; tel. 770-488-6250; fax 770-488-6352 kpazol@cdc.gov Y1 - 2010/03// PY - 2010 DA - March 2010 SP - 208 EP - 217 PB - Oxford University Press, UK VL - 125 IS - 2 SN - 0033-3549, 0033-3549 KW - Population groups, population policy, and demographics - Family planning KW - Population groups, population policy, and demographics - Women KW - Education and education policy - Statistics, research, research methods, and research support KW - Condoms KW - Abortion KW - Women KW - Surveys KW - Demographics KW - Contraceptives KW - Pregnancy KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58840740?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Public+Health+Reports&rft.atitle=Condoms+for+Dual+Protection%3A+Patterns+of+Use+with+Highly+Effective+Contraceptive+Methods&rft.au=Pazol%2C+Karen%3BKramer%2C+Michael+R%3BHogue%2C+Carol+J&rft.aulast=Pazol&rft.aufirst=Karen&rft.date=2010-03-01&rft.volume=125&rft.issue=2&rft.spage=208&rft.isbn=&rft.btitle=&rft.title=Public+Health+Reports&rft.issn=00333549&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2010-04-07 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Condoms; Women; Pregnancy; Abortion; Contraceptives; Surveys; Demographics ER - TY - JOUR T1 - Gender gap in parents' financing strategy for hospitalization of their children: evidence from India AN - 57357157; 201006017 AB - The missing women dilemma in India has sparked great interest in investigating gender discrimination in the provision of health care in the country. No studies, however, have directly examined discrimination in health-care financing strategies in the case of severe illness of sons versus daughters. In this paper, we hypothesize that households who face tight budget constraints are more likely to spend their meager resources on hospitalization of boys rather than girls. We use the 60th round of the Indian National Sample Survey (2004) and a multinomial logit model to test this hypothesis and to throw some light on this important but overlooked issue. The results reveal that boys are much more likely to be hospitalized than girls. When it comes to financing, the gap in the usage of household income and savings is relatively small, while the gender gap in the probability of hospitalization and usage of more onerous financing strategies is very high. Ceteris paribus, the probability of boys to be hospitalized by financing from borrowing, sale of assets, help from friends, etc. is much higher than that of girls. Moreover, in line with our theoretical framework, the results indicate that the gender gap intensifies as we move from the richest to poorest households. [Copyright John Wiley and Sons, Ltd.] JF - Health Economics AU - Asfaw, Abay AU - Lamanna, Francesca AU - Klasen, Stephan AD - National Institute for Occupational Safety and Health, Center for Disease Control and Prevention, Washington, DC, USA Y1 - 2010/03// PY - 2010 DA - March 2010 SP - 265 EP - 279 PB - John Wiley, Chichester UK VL - 19 IS - 3 SN - 1057-9230, 1057-9230 KW - Hospitalization KW - Financing KW - Households KW - Hospitalized KW - Gender KW - India KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/57357157?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Health+Economics&rft.atitle=Gender+gap+in+parents%27+financing+strategy+for+hospitalization+of+their+children%3A+evidence+from+India&rft.au=Asfaw%2C+Abay%3BLamanna%2C+Francesca%3BKlasen%2C+Stephan&rft.aulast=Asfaw&rft.aufirst=Abay&rft.date=2010-03-01&rft.volume=19&rft.issue=3&rft.spage=265&rft.isbn=&rft.btitle=&rft.title=Health+Economics&rft.issn=10579230&rft_id=info:doi/10.1002%2Fhec.1468 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-04-07 N1 - Last updated - 2016-09-27 N1 - CODEN - HEECEZ N1 - SubjectsTermNotLitGenreText - Financing; Gender; Households; Hospitalization; Hospitalized; India DO - http://dx.doi.org/10.1002/hec.1468 ER - TY - JOUR T1 - Global policies and practices for managing persons exposed to multidrug-resistant tuberculosis AN - 21500945; 12491517 AB - SETTING: In the 1960s, treatment for latent tuberculosis infection (LTBI) with isoniazid proved to be so effective, safe, and inexpensive that research into alternative treatments virtually ceased. Now that multidrug-resistant tuberculosis (MDR-TB) is widespread, no data are available to guide the management of persons exposed to MDR-TB (contacts). METHODS: We surveyed National TB Program directors and MDR-TB program managers about current practices for managing MDR-TB contacts in countries with an MDR-TB prevalence of >2% in new patients and those with programs for managing MDR-TB. RESULTS: Of 35 countries that met the survey criteria, 25 (71%) responded; 24 of these (96%) have a guideline for managing TB contacts. Of these, 19 (76%) usually or always evaluated contacts and treated LTBI. In contrast, 10 (40%) countries reported having a guideline for managing MDR-TB contacts, 11 (44%) usually or always evaluated MDR-TB contacts, and 9 (36%) treated LTBI. Only two (8%) used a regimen that has activity against MDR-TB. Lack of evidence or guidelines was the main reason for not treating MDR-TB contacts. CONCLUSIONS: Management of MDR-TB contacts is inconsistent and ineffective due to lack of evidence-based guidelines. There is an urgent need to generate evidence to guide policy. JF - International Journal of Tuberculosis and Lung Disease AU - Cain, K P AU - Nelson, L J AU - Cegielski, J P AD - Division of Tuberculosis Elimination, CDC, 1600 Clifton Road, MS-E-10, Atlanta, GA 30333, USA, kcain@cdc.gov Y1 - 2010/03// PY - 2010 DA - Mar 2010 SP - 269 EP - 274 PB - International Union Against Tuberculosis and Lung Disease VL - 14 IS - 3 SN - 1027-3719, 1027-3719 KW - Microbiology Abstracts B: Bacteriology KW - Data processing KW - Mycobacterium KW - Drug resistance KW - Lung diseases KW - Tuberculosis KW - Infection KW - Isoniazid KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21500945?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.atitle=Global+policies+and+practices+for+managing+persons+exposed+to+multidrug-resistant+tuberculosis&rft.au=Cain%2C+K+P%3BNelson%2C+L+J%3BCegielski%2C+J+P&rft.aulast=Cain&rft.aufirst=K&rft.date=2010-03-01&rft.volume=14&rft.issue=3&rft.spage=269&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Tuberculosis+and+Lung+Disease&rft.issn=10273719&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2013-09-20 N1 - SubjectsTermNotLitGenreText - Data processing; Drug resistance; Lung diseases; Tuberculosis; Infection; Isoniazid; Mycobacterium ER - TY - JOUR T1 - Detection of Molecular Markers of Drug Resistance in 2009 Pandemic Influenza A (H1N1) Viruses by Pyrosequencing , AN - 21489261; 12495880 AB - The M2 blockers amantadine and rimantadine and the neuraminidase (NA) inhibitors (NAIs) oseltamivir and zanamivir are approved by the FDA for use for the control of influenza A virus infections. The 2009 pandemic influenza A (H1N1) viruses (H1N1pdm) are reassortants that acquired M and NA gene segments from a Eurasian adamantane-resistant swine influenza virus. NAI resistance in the H1N1pdm viruses has been rare, and its occurrence is mainly limited to oseltamivir-exposed patients. The pyrosequencing assay has been proven to be a useful tool in surveillance for drug resistance in seasonal influenza A viruses. We provide a protocol which allows the detection of adamantane resistance markers as well as the I43T change, which is unique to the H1N1pdm M2 protein. The protocol also allows the detection of changes at residues V116, I117, E119, Q136, K150, D151, D199, I223, H275, and N295 in the NA, known to alter NAI drug susceptibility. We report on the detection of the first cases of the oseltamivir resistance-conferring mutation H275Y and the I223V change in viruses from the United States using the approach described in this study. Moreover, the assay permits the quick identification of the major NA group (V106/N248, I106/D248, or I106/N248) to which a pandemic virus belongs. Pyrosequencing is well suited for the detection of drug resistance markers and signature mutations in the M and NA gene segments of the pandemic H1N1 influenza viruses. JF - Antimicrobial Agents & Chemotherapy AU - Deyde, Varough M AU - Sheu, Tiffany G AU - Trujillo, AAngelica AU - Okomo-Adhiambo, Margaret AU - Garten, Rebecca AU - Klimov, Alexander I AU - Gubareva, Larisa V AD - Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta Georgia 30333, lqg3@cdc.gov Y1 - 2010/03// PY - 2010 DA - Mar 2010 SP - 1102 EP - 1110 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 54 IS - 3 SN - 0066-4804, 0066-4804 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Virology & AIDS Abstracts KW - Influenza A KW - Drug resistance KW - Exo-a-sialidase KW - Swine influenza KW - swine influenza virus KW - Infection KW - Zanamivir KW - Oseltamivir KW - pandemics KW - Influenza A virus KW - Amantadine KW - Mutation KW - A 01340:Antibiotics & Antimicrobials KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21489261?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Detection+of+Molecular+Markers+of+Drug+Resistance+in+2009+Pandemic+Influenza+A+%28H1N1%29+Viruses+by+Pyrosequencing+%2C&rft.au=Deyde%2C+Varough+M%3BSheu%2C+Tiffany+G%3BTrujillo%2C+AAngelica%3BOkomo-Adhiambo%2C+Margaret%3BGarten%2C+Rebecca%3BKlimov%2C+Alexander+I%3BGubareva%2C+Larisa+V&rft.aulast=Deyde&rft.aufirst=Varough&rft.date=2010-03-01&rft.volume=54&rft.issue=3&rft.spage=1102&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.01417-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2015-09-30 N1 - SubjectsTermNotLitGenreText - pandemics; Drug resistance; Influenza A; Exo-a-sialidase; Swine influenza; Infection; Amantadine; Zanamivir; Mutation; Oseltamivir; Influenza A virus; swine influenza virus DO - http://dx.doi.org/10.1128/AAC.01417-09 ER - TY - JOUR T1 - Rapid Identification and Discrimination of Brucella Isolates by Use of Real-Time PCR and High-Resolution Melt Analysis AN - 21297353; 12496148 AB - Definitive identification of Brucella species remains a challenge due to the high degree of genetic homology shared within the genus. We report the development of a molecular technique which utilizes real-time PCR followed by high-resolution melt (HRM) curve analysis to reliably type members of this genus. Using a panel of seven primer sets, we tested 153 Brucella spp. isolates with >99% accuracy compared to traditional techniques. This assay provides a useful diagnostic tool that can rapidly type Brucella isolates and has the potential to detect novel species. This approach may also prove helpful for clinical, epidemiological and veterinary investigations. JF - Journal of Clinical Microbiology AU - Winchell, Jonas M AU - Wolff, Bernard J AU - Tiller, Rebekah AU - Bowen, Michael D AU - Hoffmaster, Alex R AD - National Center for Immunization and Respiratory Diseases, jwinchell@cdc.gov Y1 - 2010/03// PY - 2010 DA - Mar 2010 SP - 697 EP - 702 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 48 IS - 3 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Homology KW - Polymerase chain reaction KW - Brucella KW - Primers KW - J 02310:Genetics & Taxonomy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21297353?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Rapid+Identification+and+Discrimination+of+Brucella+Isolates+by+Use+of+Real-Time+PCR+and+High-Resolution+Melt+Analysis&rft.au=Winchell%2C+Jonas+M%3BWolff%2C+Bernard+J%3BTiller%2C+Rebekah%3BBowen%2C+Michael+D%3BHoffmaster%2C+Alex+R&rft.aulast=Winchell&rft.aufirst=Jonas&rft.date=2010-03-01&rft.volume=48&rft.issue=3&rft.spage=697&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.02021-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2013-07-15 N1 - SubjectsTermNotLitGenreText - Homology; Polymerase chain reaction; Primers; Brucella DO - http://dx.doi.org/10.1128/JCM.02021-09 ER - TY - JOUR T1 - Effect of Carbon Dioxide on Broth Microdilution Susceptibility Testing of Brucella spp. AN - 21283763; 12496136 AB - Since some strains of Brucella species may require carbon dioxide for growth, a multilaboratory study was conducted to compare broth microdilution susceptibility results using ambient air (AA) and 5% CO2 incubation conditions. Six antimicrobial agents were tested against 39 Brucella isolates. Aminoglycoside MICs tended to be 1 log2 dilution higher in CO2 than in AA; tetracycline-class MICs to be 1 log2 dilution lower in CO2. JF - Journal of Clinical Microbiology AU - Lonsway, David R AU - Jevitt, Laura A AU - Uhl, James R AU - Cockerill III, Franklin R AU - Anderson, Mary E AU - Sullivan, Maureen M AU - De, Barun K AU - Edwards, Jonathan R AU - Patel, Jean B AD - Division of Healthcare Quality Promotion, dul7@cdc.gov Y1 - 2010/03// PY - 2010 DA - Mar 2010 SP - 952 EP - 956 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 48 IS - 3 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Brucella KW - Carbon dioxide KW - Minimum inhibitory concentration KW - Antimicrobial agents KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21283763?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Effect+of+Carbon+Dioxide+on+Broth+Microdilution+Susceptibility+Testing+of+Brucella+spp.&rft.au=Lonsway%2C+David+R%3BJevitt%2C+Laura+A%3BUhl%2C+James+R%3BCockerill+III%2C+Franklin+R%3BAnderson%2C+Mary+E%3BSullivan%2C+Maureen+M%3BDe%2C+Barun+K%3BEdwards%2C+Jonathan+R%3BPatel%2C+Jean+B&rft.aulast=Lonsway&rft.aufirst=David&rft.date=2010-03-01&rft.volume=48&rft.issue=3&rft.spage=952&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.01860-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2013-07-15 N1 - SubjectsTermNotLitGenreText - Carbon dioxide; Minimum inhibitory concentration; Antimicrobial agents; Brucella DO - http://dx.doi.org/10.1128/JCM.01860-09 ER - TY - JOUR T1 - Meningococcal conjugate vaccination among adolescents aged 13-17 years, United States, 2007 AN - 1500788221; 19046911 AB - Background An estimated 1000-2000 cases of invasive meningococcal diseases occur annually in the United States. In 2005, a new quadrivalent meningococcal conjugate vaccine (MCV4) was approved and, because of supply constraints, was recommended for routine vaccination of some groups of adolescents. In August 2007, vaccination recommendations were expanded for all adolescents 11-18 years. Methods We analyzed data from the 2007 National Immunization Survey-Teen (NIS-Teen), a nationally representative random digit dialed telephone survey. Estimates of MCV4 coverage were assessed from provider-reported vaccination histories. A multivariable logistic regression analysis and predictive marginal model were performed to identify factors independently associated with MCV4 vaccination. Results Provider-reported vaccination histories were available for 2947 adolescents aged 13-17 years with a response rate of 55.9%. Overall, MCV4 coverage was 32.4% (95% confidence interval (CI)=30.2-34.7%) in 2007. Vaccination coverage was similar among adolescents aged 13-14 years compared to those aged 15-17 years (32.1% vs. 32.6%, respectively). Coverage was 30.6% for non-Hispanic whites, 35.9% for non-Hispanic blacks, and 36.1% for Hispanics; however, these variations were not statistically significant. Characteristics independently associated with a higher likelihood of MCV4 vaccination included having greater than or equal to 2 physician contacts in the past year, having a well child visit at age 11-12 years, and ever having a doctor recommendation for meningitis vaccination of the adolescent. Conclusions In 2007, MCV4 coverage among 13-17 years old increased 20.7 percentage points from 2006. Achieving high vaccination coverage among adolescents will be challenging. Targeting adolescents with no health insurance and no recent healthcare provider visits may be important to increase coverage. JF - Vaccine AU - Lu, Peng-jun AU - Jain, Nidhi AU - Cohn, Amanda C AD - Immunization Services Division, National Center for Immunization and Respiratory Diseases, CCID, Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Atlanta, GA 30333, United States Y1 - 2010/03// PY - 2010 DA - Mar 2010 SP - 2350 EP - 2355 PB - Elsevier B.V., The Boulevard Kidlington Oxford OX5 1GB United Kingdom VL - 28 IS - 11 SN - 0264-410X, 0264-410X KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Age KW - Data processing KW - Adolescence KW - Invasive meningococcal disease KW - Regression analysis KW - Statistical analysis KW - Neisseria meningitidis KW - Vaccines KW - Vaccination KW - Models KW - Meningitis KW - F 06905:Vaccines KW - J 02350:Immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1500788221?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Meningococcal+conjugate+vaccination+among+adolescents+aged+13-17+years%2C+United+States%2C+2007&rft.au=Lu%2C+Peng-jun%3BJain%2C+Nidhi%3BCohn%2C+Amanda+C&rft.aulast=Lu&rft.aufirst=Peng-jun&rft.date=2010-03-01&rft.volume=28&rft.issue=11&rft.spage=2350&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/10.1016%2Fj.vaccine.2009.12.032 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-02-01 N1 - Last updated - 2014-05-15 N1 - SubjectsTermNotLitGenreText - Age; Data processing; Invasive meningococcal disease; Adolescence; Statistical analysis; Regression analysis; Vaccines; Vaccination; Meningitis; Models; Neisseria meningitidis DO - http://dx.doi.org/10.1016/j.vaccine.2009.12.032 ER - TY - JOUR T1 - Cardiorespiratory Fitness Levels Among US Adults 20-49 Years of Age: Findings From the 1999-2004 National Health and Nutrition Examination Survey AN - 745644089; 13150760 AB - Data from the 1999-2004 National Health and Nutrition Examination Survey were used to describe the distribution of cardiorespiratory fitness and its association with obesity and leisure-time physical activity (LTPA) for adults 20-49 years of age without physical limitations or indications of cardiovascular disease. A sample of 7,437 adults aged 20-49 years were examined at a mobile examination center. Of 4,860 eligible for a submaximal treadmill test, 3,250 completed the test and were included in the analysis. The mean maximal oxygen uptake (max) was estimated as 44.5, 42.8, and 42.2 mL/kg/minute for men 20-29, 30-39, and 40-49 years of age, respectively. For women, it was 36.5, 35.4, and 34.4 mL/kg/minute for the corresponding age groups. Non-Hispanic black women had lower fitness levels than did non-Hispanic white and Mexican-American women. Regardless of gender or race/ethnicity, people who were obese had a significantly lower estimated maximal oxygen uptake than did nonobese adults. Furthermore, a positive association between fitness level and LTPA participation was observed for both men and women. These results can be used to track future population assessments and to evaluate interventions. The differences in fitness status among population subgroups and by obesity status or LTPA can also be used to develop health policies and targeted educational campaigns. JF - American Journal of Epidemiology AU - Wang, Chia-Yih AU - Haskell, William L AU - Farrell, Stephen W AU - LaMonte, Michael J AU - Blair, Steven N AU - Curtin, Lester R AU - Hughes, Jeffery P AU - Burt, Vicki L Y1 - 2010/02/15/ PY - 2010 DA - 2010 Feb 15 SP - 426 EP - 435 PB - Oxford University Press, Oxford Journals Health, Great Clarendon Street Oxford OX2 6DP UK VL - 171 IS - 4 SN - 0002-9262, 0002-9262 KW - Physical Education Index KW - Evaluation KW - Fitness KW - Obesity KW - Women KW - Surveys KW - Health KW - Adults KW - Nutrition KW - Cardiorespiratory endurance KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745644089?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Epidemiology&rft.atitle=Cardiorespiratory+Fitness+Levels+Among+US+Adults+20-49+Years+of+Age%3A+Findings+From+the+1999-2004+National+Health+and+Nutrition+Examination+Survey&rft.au=Wang%2C+Chia-Yih%3BHaskell%2C+William+L%3BFarrell%2C+Stephen+W%3BLaMonte%2C+Michael+J%3BBlair%2C+Steven+N%3BCurtin%2C+Lester+R%3BHughes%2C+Jeffery+P%3BBurt%2C+Vicki+L&rft.aulast=Wang&rft.aufirst=Chia-Yih&rft.date=2010-02-15&rft.volume=171&rft.issue=4&rft.spage=426&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Epidemiology&rft.issn=00029262&rft_id=info:doi/10.1093%2Faje%2Fkwp412 LA - English DB - Physical Education Index N1 - Date revised - 2010-07-01 N1 - Last updated - 2013-11-04 N1 - SubjectsTermNotLitGenreText - Fitness; Evaluation; Obesity; Women; Surveys; Health; Adults; Nutrition; Cardiorespiratory endurance DO - http://dx.doi.org/10.1093/aje/kwp412 ER - TY - JOUR T1 - Detection of antiviral resistance and genetic lineage markers in influenza B virus neuraminidase using pyrosequencing AN - 877570680; 13014883 AB - We report here the design of a pyrosequencing approach for the detection of molecular markers of resistance to the neuraminidase inhibitors zanamivir and oseltamivir in influenza viruses of type B. Primers were designed to analyze the sequences at eight amino acid positions E119, R152, D198, I222, S250, H274, R371, and G402 (universal A/N2 numbering) in the neuraminidase (NA) which have been previously found to be associated with resistance or reduced susceptibility to oseltamivir and/or zanamivir in the NA inhibition assay. In addition, the designed primers could be utilized to the distinguish between the NAs of influenza B viruses from the two major lineages (Victoria and Yamagata) that have co-circulated globally in recent years, thus providing a valuable tool for virus strain surveillance. JF - Antiviral Research AU - Sheu, Tiffany G AU - Deyde, Varough M AU - Garten, Rebecca J AU - Klimov, Alexander I AU - Gubareva, Larisa V AD - Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA, lgubareva@cdc.gov Y1 - 2010/02// PY - 2010 DA - Feb 2010 SP - 354 EP - 360 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 85 IS - 2 SN - 0166-3542, 0166-3542 KW - Virology & AIDS Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Influenza B KW - Neuraminidase KW - Resistance KW - Genetic analysis KW - Evolution KW - Influenza KW - Exo-a-sialidase KW - Primers KW - Disease resistance KW - Zanamivir KW - Influenza B virus KW - Oseltamivir KW - A 01340:Antibiotics & Antimicrobials KW - V 22340:Antiviral Agents UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/877570680?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antiviral+Research&rft.atitle=Detection+of+antiviral+resistance+and+genetic+lineage+markers+in+influenza+B+virus+neuraminidase+using+pyrosequencing&rft.au=Sheu%2C+Tiffany+G%3BDeyde%2C+Varough+M%3BGarten%2C+Rebecca+J%3BKlimov%2C+Alexander+I%3BGubareva%2C+Larisa+V&rft.aulast=Sheu&rft.aufirst=Tiffany&rft.date=2010-02-01&rft.volume=85&rft.issue=2&rft.spage=354&rft.isbn=&rft.btitle=&rft.title=Antiviral+Research&rft.issn=01663542&rft_id=info:doi/10.1016%2Fj.antiviral.2009.10.022 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-10-01 N1 - Last updated - 2015-10-15 N1 - SubjectsTermNotLitGenreText - Influenza; Influenza B; Exo-a-sialidase; Primers; Disease resistance; Zanamivir; Oseltamivir; Influenza B virus DO - http://dx.doi.org/10.1016/j.antiviral.2009.10.022 ER - TY - JOUR T1 - Host cell selection of influenza neuraminidase variants: Implications for drug resistance monitoring in A(H1N1) viruses AN - 877570656; 13014878 AB - The neuraminidase inhibitors (NAIs), oseltamivir and zanamivir, are essential for treatment and prevention of influenza A and B infections. Oseltamivir resistance among influenza A (H1N1) viruses rapidly emerged and spread globally during the 2007-2008 and 2008-2009 influenza seasons. Approximately 20% and 90% of viruses tested for NAI susceptibility at CDC during these seasons, respectively, were resistant to oseltamivir (IC50 a14100-3000 time>those of sensitive viruses), based on the chemiluminescent NA inhibition assay. Pyrosequencing analysis confirmed H274Y mutation (H275Y in N1 numbering) in the neuraminidase (NA) gene of oseltamivir-resistant viruses. Full NA sequence analysis of a subset of oseltamivir-resistant and sensitive virus isolates from both seasons (n =725) showed that 53 (7.3%) had mutations at residue D151 (Da'E/G/N), while 9 (1.2%) had mutations at Q136 (Qa'K) and 2 (0.3%) had mutations at both residues. Viruses with very high IC50 for oseltamivir and peramivir, and elevated IC50 for zanamivir, had H274Y in addition to mutations at D151 and/or Q136, residues which can potentially confer NAI resistance based on recent N1 NA crystal structure data. Mutations at D151 without H274Y, did not elevate IC50 for any tested NAI, however, Q136K alone significantly reduced susceptibility to zanamivir (36-fold), peramivir (80-fold) and A-315675 (114-fold) but not oseltamivir. Mutations at D151 and Q136 were present only in MDCK grown viruses but not in matching original clinical specimens (n =33) which were available for testing, suggesting that these variants were the result of cell culture selection or they were present in very low proportions. Our findings provide evidence that propagation of influenza virus outside its natural host may lead to selection of virus variants with mutations in the NA that affect sensitivity to NAIs and thus poses implications for drug resistance monitoring and diagnostics. JF - Antiviral Research AU - Okomo-Adhiambo, Margaret AU - Nguyen, Ha T AU - Sleeman, Katrina AU - Sheu, Tiffany G AU - Deyde, Varough M AU - Garten, Rebecca J AU - Xu, Xiyan AU - Shaw, Michael W AU - Klimov, Alexander I AU - Gubareva, Larisa V AD - Virus Surveillance and Diagnosis Branch, Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Mail Stop G-16, 1600 Clifton Road Atlanta GA, USA, lgubareva@cdc.gov Y1 - 2010/02// PY - 2010 DA - Feb 2010 SP - 381 EP - 388 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 85 IS - 2 SN - 0166-3542, 0166-3542 KW - Virology & AIDS Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Cell culture KW - Antiviral resistance KW - Tamiflu KW - Relenza KW - Peramivir KW - A-315675 KW - Influenza virus KW - Data processing KW - Influenza A KW - Drug resistance KW - Exo-a-sialidase KW - Crystal structure KW - Infection KW - Mutation KW - Zanamivir KW - Oseltamivir KW - A 01340:Antibiotics & Antimicrobials KW - V 22340:Antiviral Agents UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/877570656?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antiviral+Research&rft.atitle=Host+cell+selection+of+influenza+neuraminidase+variants%3A+Implications+for+drug+resistance+monitoring+in+A%28H1N1%29+viruses&rft.au=Okomo-Adhiambo%2C+Margaret%3BNguyen%2C+Ha+T%3BSleeman%2C+Katrina%3BSheu%2C+Tiffany+G%3BDeyde%2C+Varough+M%3BGarten%2C+Rebecca+J%3BXu%2C+Xiyan%3BShaw%2C+Michael+W%3BKlimov%2C+Alexander+I%3BGubareva%2C+Larisa+V&rft.aulast=Okomo-Adhiambo&rft.aufirst=Margaret&rft.date=2010-02-01&rft.volume=85&rft.issue=2&rft.spage=381&rft.isbn=&rft.btitle=&rft.title=Antiviral+Research&rft.issn=01663542&rft_id=info:doi/10.1016%2Fj.antiviral.2009.11.005 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-10-01 N1 - Last updated - 2015-10-15 N1 - SubjectsTermNotLitGenreText - Data processing; Drug resistance; Influenza A; Crystal structure; Exo-a-sialidase; Cell culture; Infection; Zanamivir; Mutation; Oseltamivir; Influenza virus DO - http://dx.doi.org/10.1016/j.antiviral.2009.11.005 ER - TY - JOUR T1 - Reaching Linguistically Isolated People: Findings from a Telephone Survey Using Real-time Interpreters AN - 754044169; 201053724 AB - We can no longer ignore nonresponse rates in telephone surveys because of a language barrier (i.e., people who could not speak either English or Spanish) and the corresponding potential for bias in estimates from surveys that involve only English- or Spanish-speaking respondents. Building on a few published studies focusing on this problem, a pilot study was conducted in California as part of the Behavioral Risk Factor Surveillance System (BRFSS), the world's largest ongoing public health telephone survey. The aim of this follow-up study is to evaluate the effectiveness of conducting BRFSS interviews of non-English- and non-Spanish-speaking respondents via real-time interpreters. One hundred and ninety-five people identified as having a language barrier in the 2006 California BRFSS were interviewed with the assistance of on-phone interpreters. The use of real-time interpreters increased the number of completed interviews among Asian respondents in the California BRFSS from 262 to 400 and allowed a more reliable examination of key health conditions and behavioral risk factors among Asian Americans. In addition, the study reached persons with demographic profiles different from those typically interviewed in English or Spanish. The methodology used in this study might be an effective tool for telephone survey researchers to consider using to reach linguistically isolated respondents. [Reprinted by permission of Sage Publications Inc., copyright holder.] JF - Field Methods AU - Hu, S Sean AU - Link, Michael W AU - Mokdad, Ali H AD - Centers for Disease Control and Prevention, Atlanta, GA, shu@cdc.gov shu@cdc.gov Y1 - 2010/02// PY - 2010 DA - February 2010 SP - 39 EP - 56 PB - Sage Publications, Thousand Oaks CA VL - 22 IS - 1 SN - 1525-822X, 1525-822X KW - BRFSS RDD language barrier minority interpreter KW - California KW - Public Health KW - English Language KW - Health Problems KW - Constraints KW - Asian Americans KW - Bias KW - Illness KW - article KW - 0514: culture and social structure; social anthropology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754044169?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocabs&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Field+Methods&rft.atitle=Reaching+Linguistically+Isolated+People%3A+Findings+from+a+Telephone+Survey+Using+Real-time+Interpreters&rft.au=Hu%2C+S+Sean%3BLink%2C+Michael+W%3BMokdad%2C+Ali+H&rft.aulast=Hu&rft.aufirst=S&rft.date=2010-02-01&rft.volume=22&rft.issue=1&rft.spage=39&rft.isbn=&rft.btitle=&rft.title=Field+Methods&rft.issn=1525822X&rft_id=info:doi/10.1177%2F1525822X09349924 LA - English DB - Sociological Abstracts N1 - Date revised - 2010-09-10 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - California; Constraints; Health Problems; Public Health; English Language; Asian Americans; Illness; Bias DO - http://dx.doi.org/10.1177/1525822X09349924 ER - TY - JOUR T1 - Is Sexual Serosorting Occurring Among HIV-Positive Injection Drug Users? Comparison Between Those with HIV-Positive Partners Only, HIV-Negative Partners Only, and Those with any Partners of Unknown Status AN - 746048677; 12600671 AB - Using baseline data from a multi-site, randomized controlled study (INSPIRE), we categorized 999 HIV-positive IDUs into three groups based on serostatus of their sex partners. Our data provide some evidence for serosorting occurring in our sample; about 40% of the sample had sex exclusively with HIV-positive partners, and about half of them reported having unprotected sex with these partners. Twenty per cent had sex exclusively with HIV-negative partners; their sexual behaviors tended to be least risky with about two-thirds reporting their sex was protected. However, we also found that another 40% had at least one partner of unknown HIV status and sexual and drug risk was the highest among them. They were also least empowered, showing attributes that may undermine HIV prevention. Some of these findings are consistent with findings from MSM studies, suggesting that partner selection practices are similar between primarily heterosexual IDUs and MSM. JF - AIDS and Behavior AU - Mizuno, Yuko AU - Purcell, David W AU - Latka, Mary H AU - Metsch, Lisa R AU - Ding, Helen AU - Gomez, Cynthia A AU - Knowlton, Amy R AD - Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road, NE Mail Stop E37, Atlanta, GA, 30333, USA, ymizuno@cdc.gov Y1 - 2010/02// PY - 2010 DA - Feb 2010 SP - 92 EP - 102 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 14 IS - 1 SN - 1090-7165, 1090-7165 KW - Risk Abstracts; Virology & AIDS Abstracts KW - sexual behavior KW - Acquired immune deficiency syndrome KW - Data processing KW - Drug abuse KW - Sexual behavior KW - Human immunodeficiency virus KW - Risk factors KW - prevention KW - Mate selection KW - Drugs KW - Sex KW - V 22360:AIDS and HIV KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/746048677?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+and+Behavior&rft.atitle=Is+Sexual+Serosorting+Occurring+Among+HIV-Positive+Injection+Drug+Users%3F+Comparison+Between+Those+with+HIV-Positive+Partners+Only%2C+HIV-Negative+Partners+Only%2C+and+Those+with+any+Partners+of+Unknown+Status&rft.au=Mizuno%2C+Yuko%3BPurcell%2C+David+W%3BLatka%2C+Mary+H%3BMetsch%2C+Lisa+R%3BDing%2C+Helen%3BGomez%2C+Cynthia+A%3BKnowlton%2C+Amy+R&rft.aulast=Mizuno&rft.aufirst=Yuko&rft.date=2010-02-01&rft.volume=14&rft.issue=1&rft.spage=92&rft.isbn=&rft.btitle=&rft.title=AIDS+and+Behavior&rft.issn=10907165&rft_id=info:doi/10.1007%2Fs10461-009-9548-8 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Data processing; Risk factors; Mate selection; Drug abuse; Sexual behavior; Drugs; Sex; sexual behavior; Acquired immune deficiency syndrome; Human immunodeficiency virus; prevention DO - http://dx.doi.org/10.1007/s10461-009-9548-8 ER - TY - JOUR T1 - Evaluation of Coumaphos Exposure Among Tick Eradication Workers AN - 746004458; 12580677 AB - Objective: To evaluate both the cholinesterase monitoring program and newer field methods of determining coumaphos exposure among tick eradication workers. Methods: Measured blood cholinesterase by the Ellman and field testing methods and tested urine for chlorferon pre- and postshift; conducted personal air sampling, patch sampling of clothing, and wipe sampling of hands for coumaphos. Results: Fifteen workers had normal plasma cholinesterase and acetylcholinesterase levels. No significant changes occurred pre- to postshift. High correlation was found between plasma cholinesterase and acetylcholinesterase levels by field testing and Ellman methods (r = 0.91, P < 0.01 and r = 0.63, P < 0.01, respectively). Chlorferon levels rose 4 to 6 hours after use (P < 0.01). Airborne coumaphos was detected in only one sample, in a trace amount. The majority of patch and hand wipe samples detected coumaphos. Conclusions: Dermal exposure to coumaphos resulted in significant increases in urinary metabolites of coumaphos. JF - Journal of Occupational and Environmental Medicine AU - Thomas, G A AU - Delaney, L J AU - Mueller, C AU - Page, E AD - NIOSH/CDC, 4676 Columbia Parkway, Mailstop R-10, Cincinnati, OH 45226, USA, epage@cdc.gov Y1 - 2010/02// PY - 2010 DA - Feb 2010 SP - 131 EP - 136 VL - 52 IS - 2 SN - 1076-2752, 1076-2752 KW - Pollution Abstracts KW - Urine KW - Ixodidae KW - Air sampling KW - Metabolites KW - Cholinesterase KW - Occupational exposure KW - Blood levels KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/746004458?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+and+Environmental+Medicine&rft.atitle=Evaluation+of+Coumaphos+Exposure+Among+Tick+Eradication+Workers&rft.au=Thomas%2C+G+A%3BDelaney%2C+L+J%3BMueller%2C+C%3BPage%2C+E&rft.aulast=Thomas&rft.aufirst=G&rft.date=2010-02-01&rft.volume=52&rft.issue=2&rft.spage=131&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+and+Environmental+Medicine&rft.issn=10762752&rft_id=info:doi/10.1097%2FJOM.0b013e3181cd7e80 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Urine; Air sampling; Metabolites; Cholinesterase; Occupational exposure; Blood levels; Ixodidae DO - http://dx.doi.org/10.1097/JOM.0b013e3181cd7e80 ER - TY - JOUR T1 - Prevalence of overweight and obesity in youth with diabetes in USA: the SEARCH for Diabetes in Youth Study AN - 744587002; 12793458 AB - Liu LL, Lawrence JM, Davis C, Liese AD, Pettitt DJ, Pihoker C, Dabelea D, Hamman R, Waitzfelder B, Kahn HS. Prevalence of overweight and obesity in youth with diabetes in USA: the SEARCH for Diabetes in Youth Study.Objective: Obesity's association with type 2 diabetes (T2DM) is well established, but is less clear with type 1 diabetes (T1DM). We calculated the prevalence of overweight and obesity among diabetic youth in the USA from a six-center, population-based study of racially and ethnically diverse youth with diabetes, and we compared these rates with estimates among nondiabetic youth.Design/setting: Diabetic participants were examined in 2001-2004 for the SEARCH for Diabetes in Youth study (SEARCH) and nondiabetic participants were examined during the same years of the National Health and Nutrition Examination Survey (NHANES).Participants: 3953 diabetic youth and 7666 nondiabetic youth aged 3-19 yr.Main outcome measures: Overweight was defined as body mass index (BMI) from the 85th to <95th percentile for age and sex and obesity defined as greater than or equal to 95th percentile. Diabetes type was categorized as T1DM or T2DM based on physician diagnosis.Results: Among youth with T2DM, the prevalence of overweight was 10.4% and obesity was 79.4%. Among youth with T1DM, 22.1% were overweight. The prevalence of overweight among youth with T1DM was higher than among those without diabetes overall (22.1% vs. 16.1%) (P <.05). The obesity rate for T1DM was 12.6% overall (range Non-Hispanic White 10.7%-African-American 20.1%).Conclusions: As expected, most of the youth with T2DM were obese. Youth with T1DM had a higher prevalence of overweight, but not of obesity, than nondiabetic youth. Future studies of obesity among youth with diabetes of all types will further our understanding of the impact of obesity on diabetes both as a risk factor and a comorbidity. JF - Pediatric Diabetes AU - Liu, Lenna L AU - Lawrence, Jean M AU - Davis, Cralen AU - Liese, Angela D AU - Pettitt, David J AU - Pihoker, Catherine AU - Dabelea, Dana AU - Hamman, Richard AU - Waitzfelder, Beth AU - Kahn, Henry S AD - iDivision of Diabetes Translation, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA Y1 - 2010/02// PY - 2010 DA - Feb 2010 SP - 4 EP - 11 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 USA VL - 11 IS - 1 SN - 1399-543X, 1399-543X KW - Physical Education Index KW - Evaluation KW - Obesity KW - Body mass KW - Risk factors KW - Physicians KW - Nutrition KW - Youth KW - Diabetes KW - Sex KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/744587002?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Pediatric+Diabetes&rft.atitle=Prevalence+of+overweight+and+obesity+in+youth+with+diabetes+in+USA%3A+the+SEARCH+for+Diabetes+in+Youth+Study&rft.au=Liu%2C+Lenna+L%3BLawrence%2C+Jean+M%3BDavis%2C+Cralen%3BLiese%2C+Angela+D%3BPettitt%2C+David+J%3BPihoker%2C+Catherine%3BDabelea%2C+Dana%3BHamman%2C+Richard%3BWaitzfelder%2C+Beth%3BKahn%2C+Henry+S&rft.aulast=Liu&rft.aufirst=Lenna&rft.date=2010-02-01&rft.volume=11&rft.issue=1&rft.spage=4&rft.isbn=&rft.btitle=&rft.title=Pediatric+Diabetes&rft.issn=1399543X&rft_id=info:doi/10.1111%2Fj.1399-5448.2009.00519.x LA - English DB - Physical Education Index N1 - Date revised - 2010-06-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Evaluation; Obesity; Risk factors; Body mass; Physicians; Nutrition; Youth; Sex; Diabetes DO - http://dx.doi.org/10.1111/j.1399-5448.2009.00519.x ER - TY - JOUR T1 - Progress Toward Eliminating Disparities in Vaccination Coverage Among U.S. Children, 2000-2008 AN - 742955597; 2010-482222 AB - The goal year for the Healthy People 2010 initiative is approaching. Purpose This article aims to assess progress toward reaching the overarching goal of eliminating disparities in vaccination coverage among young children in the U.S. Methods Coverage for the 4:3:1:3:3:1 vaccine series (at least four doses of diphtheria-tetanus-pertussis, three poliovirus, one measles-mumps-rubella, three hepatitis B, three Haemophilus influenzae type B, and one varicella vaccine) was assessed among 185,516 children in the 2000-2008 National Immunization Surveys. Observed and adjusted disparities in coverage were evaluated for various sociodemographic groups previously associated with vaccination coverage. Linear trends in disparities were assessed. Results In 2000, disparities among population segments were significant (p<0.05) for all sociodemographic factors assessed except provider participation in the Vaccines for Children program. By 2008, most disparities were smaller than those in 2000, and racial and urban/suburban/rural differences were reduced to levels below significance. Disparities between children living in suburban versus rural localities narrowed approximately 0.5% per year. Vaccination coverage increased substantially among children in all sociodemographic groups, although children without siblings were the only group to reach the 80% target by 2008. Conclusions Progress has been made toward eliminating vaccination coverage disparities among children in various sociodemographic groups in the U.S. As the end of the Healthy People 2010 goal period approaches, maintaining and advancing these reductions will require innovative strategies to reach underserved groups. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Zhao, Zhen AU - Luman, Elizabeth T AD - National Center for Immunization and Respiratory Diseases, CDC, Atlanta, Georgia Y1 - 2010/02// PY - 2010 DA - February 2010 SP - 127 EP - 137 PB - Elsevier Science, New York NY VL - 38 IS - 2 SN - 0749-3797, 0749-3797 KW - Health conditions and policy - Medicine and health care KW - Health conditions and policy - Health and health policy KW - Health conditions and policy - Diseases and disorders KW - Social conditions and policy - Social research KW - United States KW - Hepatitis KW - Health surveys KW - Child health KW - Vaccination and vaccines KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742955597?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Progress+Toward+Eliminating+Disparities+in+Vaccination+Coverage+Among+U.S.+Children%2C+2000-2008&rft.au=Zhao%2C+Zhen%3BLuman%2C+Elizabeth+T&rft.aulast=Zhao&rft.aufirst=Zhen&rft.date=2010-02-01&rft.volume=38&rft.issue=2&rft.spage=127&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2009.10.035 LA - English DB - PAIS Index N1 - Date revised - 2010-05-10 N1 - Last updated - 2016-09-28 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Vaccination and vaccines; Child health; Hepatitis; United States; Health surveys DO - http://dx.doi.org/10.1016/j.amepre.2009.10.035 ER - TY - JOUR T1 - Highly variable population-based prevalence rates of unilateral hearing loss after the application of common case definitions. AN - 742781196; pmid-19816180 AB - OBJECTIVES: This study shows how population-based estimates of the prevalence of unilateral hearing loss (UHL) in children aged 6 to 19 yrs can differ considerably with various applications of commonly accepted case definitions. It also examines demographic variables and risk factors related to UHL. DESIGN: The Third National Health and Nutrition Examination Survey, conducted from 1988 to 1994, is a national population-based, cross-sectional survey. This study examined results of audiometric testing at 0.5 to 8 kHz and demographic data from in-person examination interviews. Three definitions of UHL were used: (1) 0.5, 1, and 2 kHz > or = 15 dB pure-tone average (PTA); (2) 0.5, 1, 2, and 4 kHz > or = 15 dB PTA; and (3) 0.5, 1, and 2 kHz > or = 20 dB or PTA >25 dB at two or more frequencies above 2 kHz (3, 4, 6, and 8 kHz). Case definitions 2 and 3 are not merely subsets of case definition 1. Some overlap exists between the groups, but each case definition classifies a proportion of children who fall uniquely under that case definition. Inclusion of participants based on tympanometry results (test of middle ear function) was also examined as were demographic characteristics and risk factors associated with UHL. RESULTS: Overall, the weighted proportion of children with UHL using case definition 1 was 6.3% (approximately 3,213,000 children nationally); using case definition 2, it was 5.8% (approximately 2,958,000 nationally); using case definition 3, it was 3.0% (approximately 1,530,000 nationally). For all three case definitions, children who failed tympanometry were at higher risk for UHL than children who passed. For case definition 2, children from rural areas were at higher risk for UHL than were children from urban areas. CONCLUSIONS: This study demonstrates that different applications of well-accepted case definitions of UHL can influence population-based prevalence estimates, in this study by as much as a factor of 2. These findings highlight the importance of controlling for tympanometry status as a risk factor in such estimates. Which demographic characteristics and risk factors are significantly associated with hearing loss seem to vary depending on the case definition. These findings have implications for the interpretation of prevalence rates and risk factors in the literature on hearing loss in general. Prevalence rate estimates require careful consideration of the case definition of hearing loss, tympanometry status, and demographic characteristics. JF - Ear and hearing AU - Ross, Danielle S AU - Visser, Susanna N AU - Holstrum, W June AU - Qin, Tielin AU - Kenneson, Aileen AD - Division of Human Development and Disability, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. Y1 - 2010/02// PY - 2010 DA - Feb 2010 SP - 126 EP - 133 VL - 31 IS - 1 SN - 0196-0202, 0196-0202 KW - Index Medicus KW - National Library of Medicine KW - United States KW - Young Adult KW - Audiometry, Pure-Tone KW - Humans KW - Child KW - Nutrition Surveys KW - Risk Assessment KW - Cross-Sectional Studies KW - Acoustic Impedance Tests KW - Hearing Loss, Unilateral -- epidemiology KW - Adolescent KW - Male KW - Female KW - Hearing Loss, Unilateral -- diagnosis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742781196?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ear+and+hearing&rft.atitle=Highly+variable+population-based+prevalence+rates+of+unilateral+hearing+loss+after+the+application+of+common+case+definitions.&rft.au=Ross%2C+Danielle+S%3BVisser%2C+Susanna+N%3BHolstrum%2C+W+June%3BQin%2C+Tielin%3BKenneson%2C+Aileen&rft.aulast=Ross&rft.aufirst=Danielle&rft.date=2010-02-01&rft.volume=31&rft.issue=1&rft.spage=126&rft.isbn=&rft.btitle=&rft.title=Ear+and+hearing&rft.issn=01960202&rft_id=info:doi/ LA - English (eng) DB - ComDisDome N1 - Date revised - 2010-04-13 N1 - Last updated - 2010-09-25 ER - TY - JOUR T1 - Whole-body inhalation exposure to 1-bromopropane suppresses the IgM response to sheep red blood cells in female B6C3F1 mice and Fisher 344/N rats. AN - 733581017; 20041805 AB - 1-Bromopropane (1-BP) is categorized as a high-production-volume chemical and is currently used in the manufacture of pharmaceuticals, pesticides, and other chemicals. Its usage is estimated to be around 5 million pounds per year, resulting in the potential for widespread exposure in the workplace. Case reports and animal studies have suggested exposure to this compound may cause adverse reproductive and neurological effects. Using a battery of immunological assays, the immunotoxicity of 1-BP after whole body inhalation exposure in both mice and rats was evaluated. Significant decreases in the spleen immunoglobulin (Ig) M response to sheep red blood cells (SRBC) were observed in both mice (125-500 ppm) and rats (1000 ppm) after exposure to 1-BP for 10 wk. In addition, total spleen cells and T cells were significantly decreased after approximately 4 wk of 1-BP exposure in both mice (125-500 ppm) and rats (1000 ppm). No change in natural killer (NK) cell activity was observed. The observed alterations in spleen cellularity, phenotypic subsets, and impairment of humoral immune function across species raise further concern about human exposure to 1-BP and demonstrate the need for additional investigations into potential adverse health effects. JF - Inhalation toxicology AU - Anderson, Stacey E AU - Munson, Albert E AU - Butterworth, Leon F AU - Germolec, Dori AU - Morgan, Daniel L AU - Roycroft, Joseph A AU - Dill, Jeffrey AU - Meade, B J AD - National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA. sanderson4@cdc.gov Y1 - 2010/02// PY - 2010 DA - February 2010 SP - 125 EP - 132 VL - 22 IS - 2 KW - Biomarkers KW - 0 KW - Hydrocarbons, Brominated KW - Immunoglobulin M KW - 1-bromopropane KW - Y9746DNE68 KW - Index Medicus KW - Animals KW - Viral Plaque Assay KW - Immunity, Humoral -- drug effects KW - Sheep KW - Hydrocarbons, Brominated -- administration & dosage KW - Mice KW - Hydrocarbons, Brominated -- toxicity KW - Killer Cells, Natural -- drug effects KW - Rats KW - Phenotype KW - Mice, Inbred Strains KW - Rats, Inbred F344 KW - Inhalation Exposure KW - Spleen -- immunology KW - T-Lymphocytes -- drug effects KW - Spleen -- drug effects KW - T-Lymphocytes -- immunology KW - Female KW - Killer Cells, Natural -- immunology KW - Immunoglobulin M -- analysis KW - Immunoglobulin M -- immunology KW - Immunoglobulin M -- biosynthesis KW - Erythrocytes -- immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733581017?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Inhalation+toxicology&rft.atitle=Whole-body+inhalation+exposure+to+1-bromopropane+suppresses+the+IgM+response+to+sheep+red+blood+cells+in+female+B6C3F1+mice+and+Fisher+344%2FN+rats.&rft.au=Anderson%2C+Stacey+E%3BMunson%2C+Albert+E%3BButterworth%2C+Leon+F%3BGermolec%2C+Dori%3BMorgan%2C+Daniel+L%3BRoycroft%2C+Joseph+A%3BDill%2C+Jeffrey%3BMeade%2C+B+J&rft.aulast=Anderson&rft.aufirst=Stacey&rft.date=2010-02-01&rft.volume=22&rft.issue=2&rft.spage=125&rft.isbn=&rft.btitle=&rft.title=Inhalation+toxicology&rft.issn=1091-7691&rft_id=info:doi/10.3109%2F08958370902953910 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-03-25 N1 - Date created - 2010-01-19 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Clin Neurol Neurosurg. 1999 Sep;101(3):199-202 [10536908] J Occup Environ Med. 2007 Sep;49(9):1009-19 [17848857] Toxicology. 2000 Dec 7;156(1):1-11 [11162871] J Toxicol Environ Health A. 2002 Mar;65(5-6):383-94 [11936219] Environ Health Perspect. 2004 Sep;112(13):1319-25 [15345346] Physiol Rev. 1980 Oct;60(4):1107-66 [7001511] Fundam Appl Toxicol. 1988 May;10(4):701-16 [3396796] Cancer Res. 1989 Nov 1;49(21):5816-22 [2507138] J Immunol Methods. 1992 Jan 21;146(1):91-103 [1735786] Fundam Appl Toxicol. 1993 Nov;21(4):412-9 [8253294] Scand J Work Environ Health. 1996 Oct;22(5):387-91 [8923614] Scand J Work Environ Health. 1997 Aug;23(4):281-8 [9322819] Am J Ind Med. 1999 May;35(5):523-31 [10212706] J Pharm Pharmacol. 1955 May;7(5):314-27 [14368526] Science. 1963 Apr 26;140(3565):405 [13957684] Toxicol Appl Pharmacol. 2006 Aug 15;215(1):23-36 [16513153] J Toxicol Environ Health A. 2007 Aug;70(15-16):1381-90 [17654258] Toxicol Sci. 2000 May;55(1):116-23 [10788566] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.3109/08958370902953910 ER - TY - JOUR T1 - The Intensity of Binge Alcohol Consumption Among U.S. Adults AN - 57335232; 201007771 AB - Binge drinking (consuming five or more drinks during a drinking occasion) is responsible for more than half of the 79,000 annual deaths due to excessive drinking in the U.S. Although studies show a strong dose-response relationship between the intensity of binge drinking (i.e., the number of drinks consumed per binge episode) and adverse outcomes, there are no population-based studies assessing this measure. Purpose This study aims to analyze population-based data from a module of questions on binge drinking among U.S. adults to assess the number of drinks consumed by binge drinkers and the associated independent risk factors for consuming more drinks. Methods Data were analyzed from 14,143 adult binge drinkers who responded to the Behavioral Risk Factor Surveillance System binge drinking module in 2003 and 2004. Total drinks were calculated by summing the total number of beer, wine, and liquor-containing drinks consumed during a respondents' most recent binge drinking episode. Results Binge drinkers consumed an average of 8.0 drinks (median 6) during their most recent binge drinking episode; 70.0% of binge drinkers consumed six or more drinks, and 38.4% consumed eight or more drinks. Men consumed more drinks during their last binge episode than women (M=8.3 vs 7.0, median=7 vs 6), and those aged 18-34 years consumed more drinks than those aged >34 years for both men and women. Independent risk factors for consuming eight or more drinks included being male; being aged <35 years; being other than white race/ethnicity; having less education; not being married; binge drinking three or more times in the past 30 days; and drinking mostly beer. Conclusions Most adult binge drinkers drink in excess of the five-drink threshold defining this risky behavior. The intensity of binge drinking should be monitored regularly by health agencies to improve surveillance and to better assess the impact of interventions designed to reduce binge drinking and its consequences. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Naimi, Timothy S AU - Nelson, David E AU - Brewer, Robert D AD - Alcohol Team, Emerging Investigations and Analytic Methods Branch, Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, CDC, Atlanta, Georgia Y1 - 2010/02// PY - 2010 DA - February 2010 SP - 201 EP - 207 PB - Elsevier Science, New York NY VL - 38 IS - 2 SN - 0749-3797, 0749-3797 KW - Beer KW - Alcohol consumption KW - Binge drinking KW - Drinks KW - Risk factors KW - Surveillance KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/57335232?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=The+Intensity+of+Binge+Alcohol+Consumption+Among+U.S.+Adults&rft.au=Naimi%2C+Timothy+S%3BNelson%2C+David+E%3BBrewer%2C+Robert+D&rft.aulast=Naimi&rft.aufirst=Timothy&rft.date=2010-02-01&rft.volume=38&rft.issue=2&rft.spage=201&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2009.09.039 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-04-07 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Alcohol consumption; Binge drinking; Risk factors; Beer; Drinks; Surveillance DO - http://dx.doi.org/10.1016/j.amepre.2009.09.039 ER - TY - JOUR T1 - Inactivation of Adenoviruses, Enteroviruses, and Murine Norovirus in Water by Free Chlorine and Monochloramine AN - 21502305; 12493219 AB - Inactivation of infectious viruses during drinking water treatment is usually achieved with free chlorine. Many drinking water utilities in the United States now use monochloramine as a secondary disinfectant to minimize disinfectant by-product formation and biofilm growth. The inactivation of human adenoviruses 2, 40, and 41 (HAdV2, HAdV40, and HAdV41), coxsackieviruses B3 and B5 (CVB3 and CVB5), echoviruses 1 and 11 (E1 and E11), and murine norovirus (MNV) are compared in this study. Experiments were performed with 0.2 mg of free chlorine or 1 mg of monochloramine/liter at pH 7 and 8 in buffered reagent-grade water at 5C. CT values (disinfectant concentration x time) for 2- to 4-log10 (99 to 99.99%) reductions in virus titers were calculated by using the efficiency factor Hom model. The enteroviruses required the longest times for chlorine inactivation and MNV the least time. CVB5 required the longest exposure time, with CT values of 7.4 and 10 mg.min/liter (pH 7 and 8) for 4-log10 inactivation. Monochloramine disinfection was most effective for E1 (CT values ranged from 8 to 18 mg.min/liter for 2- and 3-log10 reductions, respectively). E11 and HAdV2 were the least susceptible to monochloramine disinfection (CT values of 1,300 and 1,600 mg-min/liter for 3-log10 reductions, respectively). Monochloramine inactivation was most successful for the adenoviruses, CVB5, and E1 at pH 7. A greater variation in inactivation rates between viruses was observed during monochloramine disinfection than during chlorine disinfection. These data will be useful in drinking water risk assessment studies and disinfection system planning. JF - Applied and Environmental Microbiology AU - Cromeans, Theresa L AU - Kahler, Amy M AU - Hill, Vincent R AD - Atlanta Research and Education Foundation, vhill@cdc.gov Y1 - 2010/02// PY - 2010 DA - Feb 2010 SP - 1028 EP - 1033 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 76 IS - 4 SN - 0099-2240, 0099-2240 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Virology & AIDS Abstracts KW - Biofilms KW - Monochloramine KW - Norovirus KW - A 01450:Environmental Pollution & Waste Treatment KW - V 22340:Antiviral Agents UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21502305?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Inactivation+of+Adenoviruses%2C+Enteroviruses%2C+and+Murine+Norovirus+in+Water+by+Free+Chlorine+and+Monochloramine&rft.au=Cromeans%2C+Theresa+L%3BKahler%2C+Amy+M%3BHill%2C+Vincent+R&rft.aulast=Cromeans&rft.aufirst=Theresa&rft.date=2010-02-01&rft.volume=76&rft.issue=4&rft.spage=1028&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/10.1128%2FAEM.01342-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Monochloramine; Norovirus DO - http://dx.doi.org/10.1128/AEM.01342-09 ER - TY - JOUR T1 - Virulence Factors Encoded by Legionella longbeachae Identified on the Basis of the Genome Sequence Analysis of Clinical Isolate D-4968 , AN - 21295489; 11917406 AB - Legionella longbeachae causes most cases of legionellosis in Australia and may be underreported worldwide due to the lack of L. longbeachae-specific diagnostic tests. L. longbeachae displays distinctive differences in intracellular trafficking, caspase 1 activation, and infection in mouse models compared to Legionella pneumophila, yet these two species have indistinguishable clinical presentations in humans. Unlike other legionellae, which inhabit freshwater systems, L. longbeachae is found predominantly in moist soil. In this study, we sequenced and annotated the genome of an L. longbeachae clinical isolate from Oregon, isolate D-4968, and compared it to the previously published genomes of L. pneumophila. The results revealed that the D-4968 genome is larger than the L. pneumophila genome and has a gene order that is different from that of the L. pneumophila genome. Genes encoding structural components of type II, type IV Lvh, and type IV Icm/Dot secretion systems are conserved. In contrast, only 42/140 homologs of genes encoding L. pneumophila Icm/Dot substrates have been found in the D-4968 genome. L. longbeachae encodes numerous proteins with eukaryotic motifs and eukaryote-like proteins unique to this species, including 16 ankyrin repeat-containing proteins and a novel U-box protein. We predict that these proteins are secreted by the L. longbeachae Icm/Dot secretion system. In contrast to the L. pneumophila genome, the L. longbeachae D-4968 genome does not contain flagellar biosynthesis genes, yet it contains a chemotaxis operon. The lack of a flagellum explains the failure of L. longbeachae to activate caspase 1 and trigger pyroptosis in murine macrophages. These unique features of L. longbeachae may reflect adaptation of this species to life in soil. JF - Journal of Bacteriology AU - Kozak, Natalia A AU - Buss, Meghan AU - Lucas, Claressa E AU - Frace, Michael AU - Govil, Dhwani AU - Travis, Tatiana AU - Olsen-Rasmussen, Melissa AU - Benson, Robert F AU - Fields, Barry S AD - Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, htv2@cdc.gov Y1 - 2010/02// PY - 2010 DA - Feb 2010 SP - 1030 EP - 1044 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 192 IS - 4 SN - 0021-9193, 0021-9193 KW - Genetics Abstracts; Biochemistry Abstracts 2: Nucleic Acids; Microbiology Abstracts B: Bacteriology KW - Macrophages KW - Clinical isolates KW - Genomes KW - Legionella pneumophila KW - Adaptations KW - virulence factors KW - Freshwater environments KW - Nucleotide sequence KW - Secretion KW - Animal models KW - Infection KW - Chemotaxis KW - Soil KW - Legionella longbeachae KW - Ankyrin KW - Caspase-1 KW - Operons KW - Flagella KW - J 02410:Animal Diseases KW - G 07770:Bacteria UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21295489?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Bacteriology&rft.atitle=Virulence+Factors+Encoded+by+Legionella+longbeachae+Identified+on+the+Basis+of+the+Genome+Sequence+Analysis+of+Clinical+Isolate+D-4968+%2C&rft.au=Kozak%2C+Natalia+A%3BBuss%2C+Meghan%3BLucas%2C+Claressa+E%3BFrace%2C+Michael%3BGovil%2C+Dhwani%3BTravis%2C+Tatiana%3BOlsen-Rasmussen%2C+Melissa%3BBenson%2C+Robert+F%3BFields%2C+Barry+S&rft.aulast=Kozak&rft.aufirst=Natalia&rft.date=2010-02-01&rft.volume=192&rft.issue=4&rft.spage=1030&rft.isbn=&rft.btitle=&rft.title=Journal+of+Bacteriology&rft.issn=00219193&rft_id=info:doi/10.1128%2FJB.01272-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Number of references - 94 N1 - Last updated - 2013-07-15 N1 - SubjectsTermNotLitGenreText - Genomes; Clinical isolates; Macrophages; Adaptations; virulence factors; Freshwater environments; Secretion; Nucleotide sequence; Animal models; Infection; Chemotaxis; Soil; Ankyrin; Caspase-1; Operons; Flagella; Legionella pneumophila; Legionella longbeachae DO - http://dx.doi.org/10.1128/JB.01272-09 ER - TY - JOUR T1 - Trends in HospitaKzation with Chronic Obstructive Pulmonary Disease--United States, 1990--2005 AN - 1412500617; 17891112 AB - Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death in the United States and a major cause of morbidity and disability. To update national estimates and examine trends for hospitalization with COPD between 1990 and 2005, we analyzed data from the National Hospital Discharge Survey (NHDS). The results indicated that an estimated 715,000 hospitalizations with COPD, or 23.6 per 10,000 population, occurred during 2005, an increase in the number and the rate of COPD hospitalizations since 1990 (370,000 hospitalizations; rate = 15.9 per 10,000 population). To reverse increases in the number of COPD hospitalizations and decrease the burden of COPD, public health programs should continue focused efforts to reduce total personal exposure to tobacco smoke, including passive smoke exposure; to occupational dusts and chemicals; and to other indoor and outdoor air pollutants linked to COPD. JF - Journal of Chronic Obstructive Pulmonary Disease AU - Brown, D W AU - Croft, J B AU - Greenland, K J AU - Giles, W H AD - Division of Adult and Community Health, National Center, for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway NE (MS K67), Atlanta, Georgia, USA, dbrown6@cdc.gov Y1 - 2010/02// PY - 2010 DA - Feb 2010 SP - 59 EP - 62 VL - 7 IS - 1 SN - 1541-2555, 1541-2555 KW - Pollution Abstracts; Health & Safety Science Abstracts KW - Smoke KW - Chemicals KW - Air pollution KW - Mortality KW - USA KW - Tobacco KW - Morbidity KW - Chronic obstructive pulmonary disease KW - Public health KW - Hospitals KW - P 0000:AIR POLLUTION KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1412500617?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Chronic+Obstructive+Pulmonary+Disease&rft.atitle=Trends+in+HospitaKzation+with+Chronic+Obstructive+Pulmonary+Disease--United+States%2C+1990--2005&rft.au=Brown%2C+D+W%3BCroft%2C+J+B%3BGreenland%2C+K+J%3BGiles%2C+W+H&rft.aulast=Brown&rft.aufirst=D&rft.date=2010-02-01&rft.volume=7&rft.issue=1&rft.spage=59&rft.isbn=&rft.btitle=&rft.title=Journal+of+Chronic+Obstructive+Pulmonary+Disease&rft.issn=15412555&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-07-01 N1 - Last updated - 2013-08-12 N1 - SubjectsTermNotLitGenreText - Air pollution; Chemicals; Smoke; Mortality; Tobacco; Morbidity; Hospitals; Public health; Chronic obstructive pulmonary disease; USA ER - TY - CPAPER T1 - Health effects of climate change T2 - 90th Annual Meeting of the American Meteorological Society AN - 742794528; 5678014 JF - 90th Annual Meeting of the American Meteorological Society AU - Schramm, Paul Y1 - 2010/01/17/ PY - 2010 DA - 2010 Jan 17 KW - Climatic changes KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742794528?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=90th+Annual+Meeting+of+the+American+Meteorological+Society&rft.atitle=Health+effects+of+climate+change&rft.au=Schramm%2C+Paul&rft.aulast=Schramm&rft.aufirst=Paul&rft.date=2010-01-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=90th+Annual+Meeting+of+the+American+Meteorological+Society&rft.issn=&rft_id=info:doi/ L2 - http://ams.confex.com/ams/90annual/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-17 N1 - Last updated - 2010-08-14 ER - TY - CPAPER T1 - Health effects of climate change T2 - The Ninth Annual AMS Student Conference and Career Fair AN - 42333695; 5651690 JF - The Ninth Annual AMS Student Conference and Career Fair AU - Schramm, Paul Y1 - 2010/01/16/ PY - 2010 DA - 2010 Jan 16 KW - Climatic changes KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42333695?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=The+Ninth+Annual+AMS+Student+Conference+and+Career+Fair&rft.atitle=Health+effects+of+climate+change&rft.au=Schramm%2C+Paul&rft.aulast=Schramm&rft.aufirst=Paul&rft.date=2010-01-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=The+Ninth+Annual+AMS+Student+Conference+and+Career+Fair&rft.issn=&rft_id=info:doi/ L2 - http://ams.confex.com/ams/90annual/techprogram/programexpanded_578.htm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - The Effect of Medicaid Expansions on the Health Insurance Coverage of Pregnant Women: An Analysis Using Deliveries AN - 881465902; 2011-104458 AB - Using data from the National Hospital Discharge Survey, this paper analyzes the effect of Medicaid eligibility expansions from 1985 to 1996 on the health insurance coverage of women giving birth. We find that the eligibility expansions reduced the proportion of pregnant women who were uninsured by approximately 10%, although the magnitude of this decrease is sensitive to specification. The decrease in the proportion of uninsured pregnant women came at the expense of a substantial reduction in private insurance coverage (crowd-out) of at least 55%. Substantial crowd-out and the relatively small change in the proportion uninsured suggest that Medicaid eligibility expansions may have had small effects on infant and maternal health. Adapted from the source document. JF - Inquiry (Rochester) AU - Dave, Dhaval M AU - Decker, Sandra L AU - Kaestner, Robert AU - Simon, Kosali Ilayperuma AD - National Center for Health Statistics, 3311 Toledo Road, Room 3316, Hyattsville, MD 20782 E-mail: esp4@cdc.gov Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 315 EP - 330 PB - Excellus Health Plan, Inc., Rochester, NY VL - 47 IS - 4 SN - 0046-9580, 0046-9580 KW - Population groups, population policy, and demographics - Women KW - Health conditions and policy - Health and health policy KW - Social conditions and policy - Public welfare and social services KW - Business and service sector - Insurance KW - Health conditions and policy - Hospitals and other health care facilities KW - Population groups, population policy, and demographics - Demography and census KW - Population groups, population policy, and demographics - Children and youth KW - Education and education policy - Statistics, research, research methods, and research support KW - Uninsured persons KW - Medicaid program KW - Women KW - Surveys KW - Health insurance KW - Insurance KW - Infants KW - Births KW - Hospitals KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/881465902?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Inquiry+%28Rochester%29&rft.atitle=The+Effect+of+Medicaid+Expansions+on+the+Health+Insurance+Coverage+of+Pregnant+Women%3A+An+Analysis+Using+Deliveries&rft.au=Dave%2C+Dhaval+M%3BDecker%2C+Sandra+L%3BKaestner%2C+Robert%3BSimon%2C+Kosali+Ilayperuma&rft.aulast=Dave&rft.aufirst=Dhaval&rft.date=2010-01-01&rft.volume=47&rft.issue=4&rft.spage=315&rft.isbn=&rft.btitle=&rft.title=Inquiry+%28Rochester%29&rft.issn=00469580&rft_id=info:doi/10.5034%2Finquiryjrnl_47.04.315 LA - English DB - PAIS Index N1 - Date revised - 2011-08-04 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Women; Medicaid program; Uninsured persons; Health insurance; Hospitals; Births; Infants; Insurance; Surveys DO - http://dx.doi.org/10.5034/inquiryjrnl_47.04.315 ER - TY - JOUR T1 - Rapid Detection of Multidrug-Resistant Mycobacterium tuberculosis by Use of Real-Time PCR and High-Resolution Melt Analysis AN - 815542732; 13918076 AB - The current study describes the development of a unique real-time PCR assay for the detection of mutations conferring drug resistance in Mycobacterium tuberculosis. The rifampicin resistance determinant region (RRDR) of rpoB and specific regions of katG and the inhA promoter were targeted for the detection of rifampin (RIF) and isoniazid (INH) resistance, respectively. Additionally, this assay was multiplexed to discriminate Mycobacterium tuberculosis complex (MTC) strains from nontuberculous Mycobacteria (NTM) strains by targeting the IS6110 insertion element. High-resolution melting (HRM) analysis following real-time PCR was used to identify M. tuberculosis strains containing mutations at the targeted loci, and locked nucleic acid (LNA) probes were used to enhance the detection of strains containing specific single-nucleotide polymorphism (SNP) transversion mutations. This method was used to screen 252 M. tuberculosis clinical isolates, including 154 RIF-resistant strains and 174 INH-resistant strains based on the agar proportion method of drug susceptibility testing (DST). Of the 154 RIF-resistant strains, 148 were also resistant to INH and therefore classified as multidrug resistant (MDR). The assay demonstrated sensitivity and specificity of 91% and 98%, respectively, for the detection of RIF resistance and 87% and 100% for the detection of INH resistance. Overall, this assay showed a sensitivity of 85% and a specificity of 98% for the detection of MDR strains. This method provides a rapid, robust, and inexpensive way to detect the dominant mutations known to confer MDR in M. tuberculosis strains and offers several advantages over current molecular and culture-based techniques. JF - Journal of Clinical Microbiology AU - Ramirez, Melissa V AU - Cowart, Kelley C AU - Campbell, Patricia J AU - Morlock, Glenn P AU - Sikes, David AU - Winchell, Jonas M AU - Posey, James E AD - Division of Tuberculosis Elimination, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention Y1 - 2010 PY - 2010 DA - 2010 SP - 4003 EP - 4009 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 48 IS - 11 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Clinical isolates KW - Agar KW - Drug resistance KW - Probes KW - Transversion mutation KW - Promoters KW - Rifampin KW - nucleic acids KW - Single-nucleotide polymorphism KW - Polymerase chain reaction KW - Multidrug resistance KW - Tuberculosis KW - RpoB protein KW - Mycobacterium tuberculosis KW - Isoniazid KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/815542732?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Rapid+Detection+of+Multidrug-Resistant+Mycobacterium+tuberculosis+by+Use+of+Real-Time+PCR+and+High-Resolution+Melt+Analysis&rft.au=Ramirez%2C+Melissa+V%3BCowart%2C+Kelley+C%3BCampbell%2C+Patricia+J%3BMorlock%2C+Glenn+P%3BSikes%2C+David%3BWinchell%2C+Jonas+M%3BPosey%2C+James+E&rft.aulast=Ramirez&rft.aufirst=Melissa&rft.date=2010-01-01&rft.volume=48&rft.issue=11&rft.spage=4003&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-11-01 N1 - Last updated - 2013-07-15 N1 - SubjectsTermNotLitGenreText - Clinical isolates; Agar; Drug resistance; Probes; Transversion mutation; Rifampin; Promoters; nucleic acids; Single-nucleotide polymorphism; Polymerase chain reaction; Tuberculosis; Multidrug resistance; RpoB protein; Isoniazid; Mycobacterium tuberculosis ER - TY - JOUR T1 - Factors Associated with Prevalent Abnormal Anal Cytology in a Large Cohort of HIV-Infected Adults in the United States AN - 807291908; 13873807 AB - Background. The prevalence of and risk factors for abnormal anal cytology among men and women with human immunodeficiency virus (HIV) infection have not been extensively investigated. Methods. The Study to Understand the Natural History of HIV and AIDS in the Era of Effective Therapy (SUN study) is a prospective cohort study of HIV-infected patients in 4 US cities. Baseline questionnaires were administered and anal samples for cytology and human papillomavirus (HPV) detection and genotyping were collected. Results. Among 471 men and 150 women (median age, 41 years), 78% of participants were receiving combination antiretroviral therapy, 41% had a CD4 super(+) cell count of 500 cells/[mu]L, and 71% had an HIV RNA viral load of <400 copies/mL. The anal cytology results were as follows: 336 participants (54%) had negative results, 96 participants (15%) had atypical squamous cells, 149 participants (24%) had low-grade squamous intraepithelial lesions, and 40 participants (6%) had high-grade squamous intraepithelial lesions. In a multivariate analysis, abnormal anal cytology was associated with number of high-risk and low-risk HPV types (adjusted odds ratio [AOR] for both, 1.28; ), nadir CD4 super(+) cell count of <50 cells/[mu]L (AOR, 2.38; ), baseline CD4 super(+) cell count of <500 cells/[mu]L (AOR, 1.75; ), and ever having receptive anal intercourse (AOR, 2.51; ). Conclusion. HIV-infected persons with multiple anal HPV types or a nadir CD4 super(+) cell count of <50 cells/[mu]L have an increased risk for abnormal anal cytology. JF - Journal of Infectious Diseases AU - Conley, L AU - Bush, T AU - Darragh, T M AU - Palefsky, J M AU - Unger, E R AU - Patel, P AU - Kojic, E M AU - Cu-Uvin, S AU - Martin, H AU - Overton, E T AU - Hammer, J AU - Henry, K AU - Vellozzi, C AU - Wood, K AU - Brooks, J T AD - National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention and Division of Viral and Rickettsial Diseases, National Center for Zoonotic, Vector-Borne and Enteric Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, ljc2@cdc.gov ljc2@cdc.gov ljc2@cdc.gov ljc2@cdc.gov ljc2@cdc.gov ljc2@cdc.gov Y1 - 2010///0, PY - 2010 DA - 0, 2010 SP - 1567 EP - 1576 PB - University of Chicago Press, P.O. Box 37005 Chicago IL 60637 USA VL - 202 IS - 10 SN - 0022-1899, 0022-1899 KW - Health & Safety Science Abstracts KW - Historical account KW - USA KW - Acquired immune deficiency syndrome KW - Age KW - anal sex KW - Human immunodeficiency virus KW - antiretroviral agents KW - infection KW - Lesions KW - Cytology KW - Human papillomavirus KW - H 6000:Natural Disasters/Civil Defense/Emergency Management UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/807291908?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Factors+Associated+with+Prevalent+Abnormal+Anal+Cytology+in+a+Large+Cohort+of+HIV-Infected+Adults+in+the+United+States&rft.au=Conley%2C+L%3BBush%2C+T%3BDarragh%2C+T+M%3BPalefsky%2C+J+M%3BUnger%2C+E+R%3BPatel%2C+P%3BKojic%2C+E+M%3BCu-Uvin%2C+S%3BMartin%2C+H%3BOverton%2C+E+T%3BHammer%2C+J%3BHenry%2C+K%3BVellozzi%2C+C%3BWood%2C+K%3BBrooks%2C+J+T&rft.aulast=Conley&rft.aufirst=L&rft.date=2010-01-01&rft.volume=202&rft.issue=10&rft.spage=1567&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1086%2F656775 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-11-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Historical account; Age; Acquired immune deficiency syndrome; anal sex; Human immunodeficiency virus; antiretroviral agents; infection; Cytology; Lesions; Human papillomavirus; USA DO - http://dx.doi.org/10.1086/656775 ER - TY - JOUR T1 - The Association of Weight Status with Physical Fitness among Chinese Children AN - 807259300; 13367889 AB - Objective. To investigate the association of weight status with physical fitness among Chinese children. Methods. A total of 6929 children aged 6-12 years were selected from 15 primary schools of 5 provincial capital cities in eastern China. The height and fasting body weight were measured. The age-, sex-specific BMI WHO criteria was used to define underweight, overweight and obesity. Physical fitness parameters including standing broad jump, 50m sprint, and 50 m [lowast] 8 shuttle run were tested. Results. The prevalence of underweight, overweight, and obesity was 3.1%, 14.9%, and 7.8%, respectively. Boys performed better than girls, and the older children performed better than their younger counterparts for all physical fitness tests. No significant difference in all three physical fitness tests were found between children with underweight and with normal weight, and they both performed better than their counterparts with overweight and obese in all three physical fitness tests. The likelihood of achieving good performance was much lower among overweight and obese children in comparison with their counterparts with normal weight ( OR=0.13-0.54). Conclusions. An inverse association of obesity with cardiorespiratory fitness, muscle explosive strength, and speed was identified among Chinese children. JF - International Journal of Pediatrics AU - Shang, Xianwen AU - Liu, Ailing AU - Li, Yanping AU - Hu, Xiaoqi AU - Du, Lin AU - Ma, Jun AU - Xu, Guifa AU - Li, Ying AU - Guo, Hongwei AU - Ma, Guansheng AD - National Institute for Nutrition and Food Safety Chinese Center for Disease Control and Prevention 29 Nan Wei Road Beijing 100050 Y1 - 2010 PY - 2010 DA - 2010 PB - Hindawi Publishing Corporation, P.O. Box 3079 Cuyahoga Falls OH 44223 USA VL - 2010 KW - Physical Education Index KW - Obesity KW - Speed KW - Schools KW - Weight KW - Objectives KW - Physical fitness KW - Performance KW - Children KW - Cardiorespiratory endurance KW - PE 070:Measurement & Evaluation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/807259300?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Pediatrics&rft.atitle=The+Association+of+Weight+Status+with+Physical+Fitness+among+Chinese+Children&rft.au=Shang%2C+Xianwen%3BLiu%2C+Ailing%3BLi%2C+Yanping%3BHu%2C+Xiaoqi%3BDu%2C+Lin%3BMa%2C+Jun%3BXu%2C+Guifa%3BLi%2C+Ying%3BGuo%2C+Hongwei%3BMa%2C+Guansheng&rft.aulast=Shang&rft.aufirst=Xianwen&rft.date=2010-01-01&rft.volume=2010&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Pediatrics&rft.issn=1687-9759&rft_id=info:doi/10.1155%2F2010%2F515414 LA - English DB - Physical Education Index N1 - Date revised - 2010-11-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Obesity; Speed; Schools; Weight; Objectives; Physical fitness; Performance; Children; Cardiorespiratory endurance DO - http://dx.doi.org/10.1155/2010/515414 ER - TY - JOUR T1 - Basic Occupational Health Services in Baoan, China AN - 754886395; 13444050 AB - Objectives: The aim of the study was to develop a model of basic occupational health services (BOHS) in Baoan, which could provide occupational health services (OHS) universally for workers and control occupational hazards. Methods: Steps involved in the BOHS strategy included construction of the BOHS system, capacity building, health training and education, surveillance of workplaces and the health of workers, risk assessment, control and evaluation processes. Results: This model provided BOHS to employees universally, especially migrant workers in small- and medium-sized enterprises (SMEs) who had been underserved. It expanded the coverage of OHS and improved their content. The knowledge and recognition rate of occupational diseases, the coverage rates of working places and workers rose significantly after three years development. Furthermore, BOHS were cost-effective and accepted by both employers and employees. Conclusions: Our experience suggests that a BOHS strategy might be a feasible and effective way of protecting the health of workers confronted with occupational hazards. JF - Journal of Occupational Health AU - Chen, Yongwen AU - Chen, Jinxi AU - Sun, Yuwei AU - Liu, Yimin AU - Wu, Likang AU - Wang, Ya AU - Yu, Shujiang AD - Center for Disease Control and Prevention of Baoan Y1 - 2010 PY - 2010 DA - 2010 SP - 82 EP - 88 PB - Japan Society for Occupational Health, Public Health Bldg., 1-29-8 Shinjuku Shinjuku-ku Tokyo 190 Japan VL - 52 IS - 1 SN - 1341-9145, 1341-9145 KW - Toxicology Abstracts; Risk Abstracts; Health & Safety Science Abstracts KW - Construction KW - Occupational hazards KW - China, People's Rep. KW - Occupational health KW - R2 23080:Industrial and labor KW - H 1000:Occupational Safety and Health KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754886395?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Occupational+Health&rft.atitle=Basic+Occupational+Health+Services+in+Baoan%2C+China&rft.au=Chen%2C+Yongwen%3BChen%2C+Jinxi%3BSun%2C+Yuwei%3BLiu%2C+Yimin%3BWu%2C+Likang%3BWang%2C+Ya%3BYu%2C+Shujiang&rft.aulast=Chen&rft.aufirst=Yongwen&rft.date=2010-01-01&rft.volume=52&rft.issue=1&rft.spage=82&rft.isbn=&rft.btitle=&rft.title=Journal+of+Occupational+Health&rft.issn=13419145&rft_id=info:doi/10.1539%2Fjoh.O9005 L2 - http://www.jstage.jst.go.jp/article/joh/52/1/82/_pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-09-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Occupational hazards; Occupational health; China, People's Rep. DO - http://dx.doi.org/10.1539/joh.O9005 ER - TY - JOUR T1 - A Review of Unintentional Injuries in Adolescents AN - 754873517; 13231886 AB - Unintentional injuries are the largest source of premature morbidity and mortality and the leading cause of death among adolescents 10-19 years of age. Fatal injury rates of males are twice those of females, and racial disparities in injury are pronounced. Transportation is the largest source of these injuries, principally as drivers and passengers, but also as cyclists and pedestrians. Other major causes involve drowning, poisonings, fires, sports and recreation, and work-related injuries. Implementing known and effective prevention strategies such as using seat belts and bicycle and motorcycle helmets, installing residential smoke alarms, reducing misuse of alcohol, strengthening graduated driver licensing laws, promoting policy change, using safety equipment in sports and leisure, and protecting adolescents at work will all contribute to reducing injuries. The frequency, severity, potential for death and disability, and costs of these injuries, together with the high success potential of prevention strategies, make injury prevention a key public health goal to improve adolescent health in the future. JF - Annual Review of Public Health AU - Sleet, DA AU - Ballesteros, M F AU - Borse, N N AD - Division of Unintentional Injury Prevention, National Center for Injury Prevention and Control, Atlanta, Georgia 30341, USA, dds6@cdc.gov Y1 - 2010 PY - 2010 DA - 2010 SP - 195 EP - 212 VL - 31 SN - 0163-7525, 0163-7525 KW - Health & Safety Science Abstracts KW - disabilities KW - Motor vehicles KW - Morbidity KW - Public health KW - sports related injuries KW - Transportation KW - prevention KW - drowning KW - Adolescents KW - seat belts KW - Alcohol KW - Mortality KW - pedestrians KW - Protective equipment KW - bicycles KW - Reviews KW - Alarm systems KW - Motorcycles KW - safety equipment KW - H 2000:Transportation UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754873517?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Annual+Review+of+Public+Health&rft.atitle=A+Review+of+Unintentional+Injuries+in+Adolescents&rft.au=Sleet%2C+DA%3BBallesteros%2C+M+F%3BBorse%2C+N+N&rft.aulast=Sleet&rft.aufirst=DA&rft.date=2010-01-01&rft.volume=31&rft.issue=&rft.spage=195&rft.isbn=&rft.btitle=&rft.title=Annual+Review+of+Public+Health&rft.issn=01637525&rft_id=info:doi/10.1146%2Fannurev.publhealth.012809.103616 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Mortality; Alcohol; disabilities; Motor vehicles; pedestrians; Protective equipment; Morbidity; Public health; sports related injuries; bicycles; Transportation; Alarm systems; Reviews; prevention; Motorcycles; Adolescents; drowning; safety equipment; seat belts DO - http://dx.doi.org/10.1146/annurev.publhealth.012809.103616 ER - TY - JOUR T1 - Reexamining Methods and Messaging for Hand Hygiene in the Era of Increasing Clostridium difficile Colonization and Infection AN - 745978293; 12845287 JF - Infection Control and Hospital Epidemiology AU - Ellingson, Katherine AU - McDonald, Clifford AD - Centers for Disease Control and Prevention, Atlanta, Georgia., kellingson@cdc.gov Y1 - 2010 PY - 2010 DA - 2010 SP - 571 EP - 573 PB - University of Chicago Press, P.O. Box 37005 Chicago IL 60637 USA, [mailto:help@press.uchicago.edu], [URL:http://www.journals.uchicago.edu/] VL - 31 IS - 6 SN - 0899-823X, 0899-823X KW - Microbiology Abstracts B: Bacteriology KW - Colonization KW - Hand KW - Clostridium difficile KW - Infection KW - Hygiene KW - Hospitals KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745978293?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Infection+Control+and+Hospital+Epidemiology&rft.atitle=Reexamining+Methods+and+Messaging+for+Hand+Hygiene+in+the+Era+of+Increasing+Clostridium+difficile+Colonization+and+Infection&rft.au=Ellingson%2C+Katherine%3BMcDonald%2C+Clifford&rft.aulast=Ellingson&rft.aufirst=Katherine&rft.date=2010-01-01&rft.volume=31&rft.issue=6&rft.spage=571&rft.isbn=&rft.btitle=&rft.title=Infection+Control+and+Hospital+Epidemiology&rft.issn=0899823X&rft_id=info:doi/10.1086%2F652773 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Colonization; Hand; Hygiene; Infection; Hospitals; Clostridium difficile DO - http://dx.doi.org/10.1086/652773 ER - TY - JOUR T1 - Household Transmission of 2009 Influenza A (H1N1) Virus after a School- Based Outbreak in New York City, April-May 2009 AN - 745977273; 12845194 AB - In April 2009, an outbreak due to infection with the 2009 pandemic influenza A (H1N1) virus (pH1N1) was investigated in a New York City high school. We surveyed household contacts of ill students to characterize the extent of transmission within households, identify contact groups at highest risk for illness, and assess the potential for preventing household transmission. Influenza-like illness (ILI) was reported by 79 of 702 household contacts (11.3% attack rate). Multivariate analysis showed that older age was protective: for each increasing year of age, the risk of ILI was reduced 5%. Additional protective factors included antiviral prophylaxis and having had a household discussion about influenza. Providing care for the index case patient and watching television with the index case patient were risk factors among parents and siblings, respectively. Fifty percent of cases occurred within 3 days of onset of illness in the student. These factors have implications for mitigating the impact of pH1N1 transmission. JF - Journal of Infectious Diseases AU - France, Anne Marie AU - Jackson, Michael AU - Schrag, Stephanie AU - Lynch, Michael AU - Zimmerman, Christopher AU - Biggerstaff, Matthew AU - Hadler, James AD - Epidemic Intelligence Service, Office of Workforce and Career Development, and National Center For Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, afrance@health.nyc.gov Y1 - 2010///0, PY - 2010 DA - 0, 2010 SP - 984 EP - 992 PB - University of Chicago Press, P.O. Box 37005 Chicago IL 60637 USA, [mailto:help@press.uchicago.edu], [URL:http://www.journals.uchicago.edu/] VL - 201 IS - 7 SN - 0022-1899, 0022-1899 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Virology & AIDS Abstracts KW - pandemics KW - Age KW - Multivariate analysis KW - Risk factors KW - Prophylaxis KW - Geriatrics KW - Siblings KW - Infection KW - Disease transmission KW - A 01340:Antibiotics & Antimicrobials KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745977273?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologya&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Household+Transmission+of+2009+Influenza+A+%28H1N1%29+Virus+after+a+School-+Based+Outbreak+in+New+York+City%2C+April-May+2009&rft.au=France%2C+Anne+Marie%3BJackson%2C+Michael%3BSchrag%2C+Stephanie%3BLynch%2C+Michael%3BZimmerman%2C+Christopher%3BBiggerstaff%2C+Matthew%3BHadler%2C+James&rft.aulast=France&rft.aufirst=Anne&rft.date=2010-01-01&rft.volume=201&rft.issue=7&rft.spage=984&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1086%2F651145 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Age; pandemics; Multivariate analysis; Risk factors; Geriatrics; Prophylaxis; Siblings; Infection; Disease transmission DO - http://dx.doi.org/10.1086/651145 ER - TY - JOUR T1 - Work-Related Non-Fatal Injuries to Adults on Farms in the U.S., 2001 and 2004 AN - 744617739; 12912715 AB - The National Institute for Occupational Safety and Health (NIOSH), in an ongoing effort to address the issue of injuries on farms in the U.S., collaborated with the USDA to complete the 2001 and 2004 Occupational Injury Surveillance of Production Agriculture Surveys (OISPAS). The OISPAS data indicated that the estimated adult working population (household and hired) on U.S. farms decreased from 6,170,940 in 2001 to 5,294,912 in 2004. The estimated number of work-related injuries decreased from 75,756 to 71,081. The rate of injury increased over this same time period (12.3 injuries per 1,000 working adults to 13.4 injuries per 1,000 working adults). The majority of these injuries occurred to adults in the age range of 45 to 54 years. The vast majority of injuries occurred to males, over 75% in both years. Animals (17%) and the ground (17%) were the source of injury in approximately 35% of injuries reported in each year. The most common injury events were "struck by objects" and falls. These two events combined accounted for over half of all work-related injuries in both 2001 and 2004. The OISPAS data indicated that although injuries are decreasing as the size of the at-risk population decreases, the rate of injury is increasing. The results of this research may be used to direct current injury prevention efforts and to plan for future injury surveillance. JF - Journal of Agricultural Safety and Health AU - Goldcamp, E M AD - NIOSH, Division of Safety Research, 1095 Willowdale Rd., Morgantown, West Virginia 26505, USA, mgoldcamp@cdc.gov Y1 - 2010/01// PY - 2010 DA - Jan 2010 SP - 41 EP - 51 VL - 16 IS - 1 SN - 1074-7583, 1074-7583 KW - Health & Safety Science Abstracts KW - USA KW - households KW - Age KW - Injuries KW - farms KW - Occupational safety KW - prevention KW - agriculture KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/744617739?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Agricultural+Safety+and+Health&rft.atitle=Work-Related+Non-Fatal+Injuries+to+Adults+on+Farms+in+the+U.S.%2C+2001+and+2004&rft.au=Goldcamp%2C+E+M&rft.aulast=Goldcamp&rft.aufirst=E&rft.date=2010-01-01&rft.volume=16&rft.issue=1&rft.spage=41&rft.isbn=&rft.btitle=&rft.title=Journal+of+Agricultural+Safety+and+Health&rft.issn=10747583&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Age; households; Injuries; farms; Occupational safety; agriculture; prevention; USA ER - TY - JOUR T1 - The role of nanotoxicology in realizing the 'helping without harm' paradigm of nanomedicine: lessons from studies of pulmonary effects of single-walled carbon nanotubes. AN - 734231327; 20059647 AB - Nano-sized materials and nano-scaled processes are widely used in many industries. They are being actively introduced as diagnostic and therapeutic in biomedicine and they are found in numerous consumer products. The small size of nanoparticles, comparable with molecular machinery of cells, may affect normal physiological functions of cells and cause cytotoxicity. Their toxic potential cannot be extrapolated from studies of larger particles due to unique physicochemical properties of nanomaterials. Therefore, the use of nanomaterials may pose unknown risks to human health and the environment. This review discusses several important issues relevant to pulmonary toxicity of nanoparticles, especially single-walled carbon nanotubes (SWCNT), their direct cytotoxic effects, their ability to cause an inflammatory response, and induce oxidative stress upon pharyngeal aspiration or inhalation. Further, recognition and engulfment of nanotubes by macrophages as they relate to phagocytosis and bio-distribution of nanotubes in tissues and circulation are discussed. The immunosuppressive effects of CNT and their significance in increased sensitivity of exposed individuals to microbial infections are summarized. Finally, data on biodegradation of SWCNT by oxidative enzymes of inflammatory cells are presented in lieu of their persistence and distribution in the body. JF - Journal of internal medicine AU - Shvedova, A A AU - Kagan, V E AD - Pathology & Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health/CDC, 1095 Willowdale Road, Morgantown, WV 26505, USA. ats1@cdc.gov Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 106 EP - 118 VL - 267 IS - 1 KW - Nanotubes, Carbon KW - 0 KW - Index Medicus KW - Inhalation KW - Animals KW - Humans KW - Oxidative Stress -- immunology KW - Lung -- immunology KW - Pulmonary Fibrosis -- immunology KW - Nanomedicine -- ethics KW - Pulmonary Fibrosis -- pathology KW - Pulmonary Fibrosis -- etiology KW - Nanoparticles -- adverse effects KW - Lung -- pathology KW - Nanotubes, Carbon -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/734231327?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+internal+medicine&rft.atitle=The+role+of+nanotoxicology+in+realizing+the+%27helping+without+harm%27+paradigm+of+nanomedicine%3A+lessons+from+studies+of+pulmonary+effects+of+single-walled+carbon+nanotubes.&rft.au=Shvedova%2C+A+A%3BKagan%2C+V+E&rft.aulast=Shvedova&rft.aufirst=A&rft.date=2010-01-01&rft.volume=267&rft.issue=1&rft.spage=106&rft.isbn=&rft.btitle=&rft.title=Journal+of+internal+medicine&rft.issn=1365-2796&rft_id=info:doi/10.1111%2Fj.1365-2796.2009.02188.x LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-02-18 N1 - Date created - 2010-01-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1111/j.1365-2796.2009.02188.x ER - TY - JOUR T1 - Resources for Clinicians: So Many Materials, So Little Time: A Checklist to Select Printed Patient Education Materials for Clinical Practice AN - 57339414; 201002745 AB - Abstract not available. JF - Journal of Midwifery & Women's Health AU - Fraze, Jami AU - Griffith, Judith AU - Green, Donata AU - McElroy, Laura AD - e-mail:jfraze@cdc.gov Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 70 EP - 73 PB - Elsevier Ltd, The Netherlands VL - 55 IS - 1 SN - 1526-9523, 1526-9523 KW - Prevention KW - Attitudes KW - Clinical practice KW - Patient education KW - HIV KW - Preventive programmes KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/57339414?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Midwifery+%26+Women%27s+Health&rft.atitle=Resources+for+Clinicians%3A+So+Many+Materials%2C+So+Little+Time%3A+A+Checklist+to+Select+Printed+Patient+Education+Materials+for+Clinical+Practice&rft.au=Fraze%2C+Jami%3BGriffith%2C+Judith%3BGreen%2C+Donata%3BMcElroy%2C+Laura&rft.aulast=Fraze&rft.aufirst=Jami&rft.date=2010-01-01&rft.volume=55&rft.issue=1&rft.spage=70&rft.isbn=&rft.btitle=&rft.title=Journal+of+Midwifery+%26+Women%27s+Health&rft.issn=15269523&rft_id=info:doi/10.1016%2Fj.jmwh.2009.07.002 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-02-03 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Attitudes; Patient education; Preventive programmes; HIV; Clinical practice; Prevention DO - http://dx.doi.org/10.1016/j.jmwh.2009.07.002 ER - TY - JOUR T1 - Late-Treated Phenylketonuria and Partial Reversibility of Intellectual Impairment AN - 57333256; 201006887 AB - Individuals with late-treated phenylketonuria (PKU) not detected by newborn screening but who followed dietary treatment for at least 12 months before 7 years of age have intelligence quotient (IQ) scores that range from severe impairment to the low-normal range. Among adults with late-treated PKU in California, 85% of those who were born from 1961 to 1978 had IQ scores of 70 or above. Longitudinal studies with repeated cognitive assessments often show average changes in cognitive test scores as high as 20-45 points. Although the severe cognitive impairment associated with untreated PKU can in many cases be partially reversed with dietary treatment, prompt initiation of treatment following newborn metabolic screening is essential for optimal development and the prevention of disability. Adapted from the source document. JF - Child Development AU - Grosse, Scott D AD - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention sgrosse@cdc.gov Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 200 EP - 211 PB - Wiley-Blackwell, Oxford UK VL - 81 IS - 1 SN - 0009-3920, 0009-3920 KW - Screening KW - Newborn babies KW - Disability KW - Test scores KW - Phenylketonuria KW - Intelligence quotient KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/57333256?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Child+Development&rft.atitle=Late-Treated+Phenylketonuria+and+Partial+Reversibility+of+Intellectual+Impairment&rft.au=Grosse%2C+Scott+D&rft.aulast=Grosse&rft.aufirst=Scott&rft.date=2010-01-01&rft.volume=81&rft.issue=1&rft.spage=200&rft.isbn=&rft.btitle=&rft.title=Child+Development&rft.issn=00093920&rft_id=info:doi/10.1111%2Fj.1467-8624.2009.01389.x LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-10-21 N1 - Last updated - 2016-09-27 N1 - CODEN - CHDEAW N1 - SubjectsTermNotLitGenreText - Intelligence quotient; Phenylketonuria; Screening; Newborn babies; Test scores; Disability DO - http://dx.doi.org/10.1111/j.1467-8624.2009.01389.x ER - TY - JOUR T1 - A century of mining safety and health research AN - 21321104; 11912780 AB - The year 2010 will mark the 100th anniversary of the beginning of the research efforts by the U.S. government to improve the health and safety of miners working in the United States. This research began in 1910 with the establishment of the U.S. Bureau of Mines (the Bureau) and it has continued during the past 10 decades, even after the closure of the Bureau in 1996. The research on safer mining technology, formerly done by the Bureau, has now been combined with National Institute for Occupational Safety and Health (NIOSH) studies of miners' health to form a unified federal research program to improve the health and safety of miners. This article describes this research and places some of the accomplishments into perspective with other activities in the U.S. Mine Safety and Health Time Line (insert). JF - Mining Engineering AU - Breslin, JA AD - NIOSH, Pittsburgh, PA, USA, jbreslin@cdc.gov Y1 - 2010/01// PY - 2010 DA - Jan 2010 SP - 33 EP - 37 PB - Society for Mining, Metallurgy and Exploration, 8307 Shaffer Parkway Littleton CO 80127-5002 USA VL - 62 IS - 1 SN - 0026-5187, 0026-5187 KW - Health & Safety Science Abstracts KW - Historical account KW - Occupational safety KW - USA KW - safety engineering KW - Mining KW - Research programs KW - Technology KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21321104?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Mining+Engineering&rft.atitle=A+century+of+mining+safety+and+health+research&rft.au=Breslin%2C+JA&rft.aulast=Breslin&rft.aufirst=JA&rft.date=2010-01-01&rft.volume=62&rft.issue=1&rft.spage=33&rft.isbn=&rft.btitle=&rft.title=Mining+Engineering&rft.issn=00265187&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - USA; safety engineering; Historical account; Mining; Occupational safety; Research programs; Technology ER - TY - JOUR T1 - First Report Worldwide of an Infant Botulism Case Due to Clostridium botulinum Type E AN - 21317222; 11915405 AB - Clostridium botulinum type E has been associated with botulism in adults but never in infants. Infant botulism type E cases have been associated with neurotoxigenic strains of C. butyricum. We report the first infant botulism case due to C. botulinum type E worldwide. JF - Journal of Clinical Microbiology AU - Luquez, Carolina AU - Dykes, Janet K AU - Yu, Patricia A AU - Raphael, Brian H AU - Maslanka, Susan E AD - Centers for Disease Control and Prevention, Atlanta, Georgia, Cluquez@cdc.gov Y1 - 2010/01// PY - 2010 DA - Jan 2010 SP - 326 EP - 328 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 48 IS - 1 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Botulism KW - Clostridium botulinum KW - Infants KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21317222?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=First+Report+Worldwide+of+an+Infant+Botulism+Case+Due+to+Clostridium+botulinum+Type+E&rft.au=Luquez%2C+Carolina%3BDykes%2C+Janet+K%3BYu%2C+Patricia+A%3BRaphael%2C+Brian+H%3BMaslanka%2C+Susan+E&rft.aulast=Luquez&rft.aufirst=Carolina&rft.date=2010-01-01&rft.volume=48&rft.issue=1&rft.spage=326&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.01420-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Number of references - 18 N1 - Last updated - 2013-07-15 N1 - SubjectsTermNotLitGenreText - Botulism; Infants; Clostridium botulinum DO - http://dx.doi.org/10.1128/JCM.01420-09 ER - TY - JOUR T1 - Impact of Varicella Vaccine on Varicella-Zoster Virus Dynamics AN - 21304586; 11915210 AB - Summary: The licensure and recommendation of varicella vaccine in the mid-1990s in the United States have led to dramatic declines in varicella incidence and varicella-related deaths and hospitalizations. Varicella outbreaks remain common and occur increasingly in highly vaccinated populations. Breakthrough varicella in vaccinated individuals is characteristically mild, typically with fewer lesions that frequently do not progress to a vesicular stage. As such, the laboratory diagnosis of varicella has grown increasingly important, particularly in outbreak settings. In this review the impact of varicella vaccine on varicella-zoster virus (VZV) disease, arising complications in the effective diagnosis and monitoring of VZV transmission, and the relative strengths and limitations of currently available laboratory diagnostic techniques are all addressed. Since disease symptoms often resolve in outbreak settings before suitable test specimens can be obtained, the need to develop new diagnostic approaches that rely on alternative patient samples is also discussed. JF - Clinical Microbiology Reviews AU - Schmid, DScott AU - Jumaan, Aisha O AD - Herpesvirus Team and National VZV Laboratory, Measles, Mumps, Rubella, and Herpesvirus Laboratory Branch, SSchmid@cdc.gov PY - 2010 SP - 202 EP - 217 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 23 IS - 1 SN - 0893-8512, 0893-8512 KW - Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts KW - Varicella-zoster virus KW - Vaccines KW - Vaccination KW - Varicella KW - Disease transmission KW - V 22400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21304586?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+Microbiology+Reviews&rft.atitle=Impact+of+Varicella+Vaccine+on+Varicella-Zoster+Virus+Dynamics&rft.au=Schmid%2C+DScott%3BJumaan%2C+Aisha+O&rft.aulast=Schmid&rft.aufirst=DScott&rft.date=2010-01-01&rft.volume=23&rft.issue=1&rft.spage=202&rft.isbn=&rft.btitle=&rft.title=Clinical+Microbiology+Reviews&rft.issn=08938512&rft_id=info:doi/10.1128%2FCMR.00031-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Number of references - 159 N1 - Last updated - 2016-01-06 N1 - SubjectsTermNotLitGenreText - Vaccines; Vaccination; Disease transmission; Varicella; Varicella-zoster virus DO - http://dx.doi.org/10.1128/CMR.00031-09 ER - TY - JOUR T1 - Steroid 5-a-Reductase Type 2 (SRD5a2) Gene Polymorphisms and Risk of Prostate Cancer: A HuGE Review AN - 21276237; 11832197 AB - Steroid 5-a-reductase type 2 (SRD5a2) is a critical enzyme in androgen metabolism. Two polymorphisms in the SRD5a2 gene, V89L (rs523349) and A49T (rs9282858), have been studied for associations with prostate cancer risk, with conflicting results. The authors conducted a systematic review and meta-analysis (1997-2007) to examine these associations and compared the results with findings from genome-wide association studies of prostate cancer. The meta-analysis included 24 case-control studies (10,088 cases and 10,120 controls for V89L and 4,998 cases and 5,451 controls for A49T). The authors found that prostate cancer was not associated with V89L (L allele vs. V allele: odds ratio=0.99, 95% confidence interval: 0.94, 1.05) and was probably not associated with A49T (T allele vs. A allele: odds ratio=1.10, 95% confidence interval: 0.86, 1.40). These results could have been distorted by spectrum-of-disease bias, convenience sampling of cases and controls, genotype misclassification, and/or confounding. Neither V89L nor A49T was included in microarray chips used for published genome-wide association studies. Analysis of well-designed population-based studies with pathway-based arrays containing common genetic variants could be useful for identifying genetic factors in prostate cancer. JF - American Journal of Epidemiology AU - Li, Jun AU - Coates, Ralph J AU - Gwinn, Marta AU - Khoury, Muin J Y1 - 2010/01/01/ PY - 2010 DA - 2010 Jan 01 SP - 1 EP - 13 PB - Oxford University Press, Oxford Journals Health, Great Clarendon Street Oxford OX2 6DP UK VL - 171 IS - 1 SN - 0002-9262, 0002-9262 KW - Genetics Abstracts; Risk Abstracts KW - epidemiology KW - genetic predisposition to disease KW - genetics KW - meta-analysis KW - polymorphism, genetic KW - prostatic neoplasms KW - SRD5a2 KW - testosterone 5-alpha-reductase KW - Genetic factors KW - Gene polymorphism KW - Enzymes KW - Population studies KW - steroids KW - Genotypes KW - Steroid hormones KW - DNA microarrays KW - Prostate cancer KW - Reviews KW - Sampling KW - prostate cancer KW - Metabolism KW - Androgens KW - R2 23060:Medical and environmental health KW - G 07700:Molecular Genetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21276237?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Epidemiology&rft.atitle=Steroid+5-a-Reductase+Type+2+%28SRD5a2%29+Gene+Polymorphisms+and+Risk+of+Prostate+Cancer%3A+A+HuGE+Review&rft.au=Li%2C+Jun%3BCoates%2C+Ralph+J%3BGwinn%2C+Marta%3BKhoury%2C+Muin+J&rft.aulast=Li&rft.aufirst=Jun&rft.date=2010-01-01&rft.volume=171&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Epidemiology&rft.issn=00029262&rft_id=info:doi/10.1093%2Faje%2Fkwp318 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Genetic factors; Prostate cancer; Reviews; Gene polymorphism; Population studies; Enzymes; Sampling; Steroid hormones; DNA microarrays; Metabolism; Androgens; Genotypes; steroids; prostate cancer DO - http://dx.doi.org/10.1093/aje/kwp318 ER - TY - JOUR T1 - Drug Resistance in Visceral Leishmaniasis AN - 21255257; 11829198 AB - Visceral leishmaniasis remains a public health problem worldwide. This illness was included by the World Health Organization in the list of neglected tropical diseases targeted for elimination by 2015. The widespread emergence of resistance to pentavalent antimonials in India where half cases occur globally and the unavailability of a vaccine in clinical use constitute major obstacles in achieving this goal. The last decade new antileishmanials became available, including the oral agent miltefosine. However, in poor endemic countries their wide use was curtailed because of the high costs, and also due to concerns of toxicity and emergence of resistance. Various mechanisms of antileishmanial resistance were identified recently in field isolates. Their elucidation will boost the design of new drugs and the molecular surveillance of resistance. Combination regimens should be evaluated in large trials. Overall, the development of antileishmanials has been generally slow; new drugs are needed. In order to control visceral leishmaniasis worldwide, treatment advances should become affordable in the poorest countries, where they are needed most. JF - Journal of Biomedicine and Biotechnology AU - Maltezou, Helena C AD - Department for Interventions in Health-Care Facilities Hellenic Center for Disease Control and Prevention 15123 Athens, helen-maltezou@ath.forthnet.gr Y1 - 2010///0, PY - 2010 DA - 0, 2010 PB - Hindawi Publishing Corporation, P.O. Box 3079 Cuyahoga Falls OH 44223 USA VL - 2010 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Microbiology Abstracts C: Algology, Mycology & Protozoology; Biotechnology and Bioengineering Abstracts KW - Organizations KW - Visceral leishmaniasis KW - Miltefosine KW - Drug resistance KW - Disease control KW - Surveillance and enforcement KW - Drug development KW - Toxicity KW - Clinical trials KW - India KW - Public health KW - Endemic species KW - Vaccines KW - Drugs KW - Biotechnology KW - K 03340:Effects of Physical & Chemical Factors KW - Q1 08484:Species interactions: parasites and diseases KW - W 30915:Pharmaceuticals & Vaccines KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21255257?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Biomedicine+and+Biotechnology&rft.atitle=Drug+Resistance+in+Visceral+Leishmaniasis&rft.au=Maltezou%2C+Helena+C&rft.aulast=Maltezou&rft.aufirst=Helena&rft.date=2010-01-01&rft.volume=2010&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Journal+of+Biomedicine+and+Biotechnology&rft.issn=1110-7251&rft_id=info:doi/10.1155%2F2010%2F617521 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - Last updated - 2016-02-04 N1 - SubjectsTermNotLitGenreText - Endemic species; Organizations; Surveillance and enforcement; Disease control; Vaccines; Toxicity; Drugs; Biotechnology; Public health; Drug resistance; Miltefosine; Visceral leishmaniasis; Drug development; Clinical trials; India DO - http://dx.doi.org/10.1155/2010/617521 ER - TY - JOUR T1 - Selenium fractionation in Se-rich soils and rock spoils in Enshi by alkaline extraction AN - 1017950652; 2012-050801 JF - Geochimica et Cosmochimica Acta AU - Qin, H B AU - Zhu, J M AU - Lei, L AU - Su, H AU - Anonymous Y1 - 2010 PY - 2010 DA - 2010 SP - 1 PB - Elsevier, New York, NY VL - 74 IS - 12, Suppl. 1 SN - 0016-7037, 0016-7037 KW - Hubei China KW - Far East KW - selenium KW - bioavailability KW - humic acids KW - ligands KW - Asia KW - inorganic acids KW - geochemistry KW - China KW - soils KW - carbonaceous composition KW - pollution KW - weathering KW - Enshi China KW - sample preparation KW - organic compounds KW - organic acids KW - humic substances KW - spoils KW - soil pollution KW - hydrochloric acid KW - fulvic acids KW - soil management KW - chemical fractionation KW - 02C:Geochemistry of rocks, soils, and sediments KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1017950652?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Geochimica+et+Cosmochimica+Acta&rft.atitle=Selenium+fractionation+in+Se-rich+soils+and+rock+spoils+in+Enshi+by+alkaline+extraction&rft.au=Qin%2C+H+B%3BZhu%2C+J+M%3BLei%2C+L%3BSu%2C+H%3BAnonymous&rft.aulast=Qin&rft.aufirst=H&rft.date=2010-01-01&rft.volume=74&rft.issue=12%2C+Suppl.+1&rft.spage=A838&rft.isbn=&rft.btitle=&rft.title=Geochimica+et+Cosmochimica+Acta&rft.issn=00167037&rft_id=info:doi/ L2 - http://goldschmidt.info/2010/abstracts/A-Z+Index.pdf http://www.sciencedirect.com/science/journal/00167037 LA - English DB - GeoRef N1 - Conference title - 20th annual V. M. Goldschmidt conference N1 - Copyright - GeoRef, Copyright 2014, American Geosciences Institute. N1 - Date revised - 2012-01-01 N1 - PubXState - NY N1 - Last updated - 2014-09-18 N1 - SubjectsTermNotLitGenreText - Asia; bioavailability; carbonaceous composition; chemical fractionation; China; Enshi China; Far East; fulvic acids; geochemistry; Hubei China; humic acids; humic substances; hydrochloric acid; inorganic acids; ligands; organic acids; organic compounds; pollution; sample preparation; selenium; soil management; soil pollution; soils; spoils; weathering ER - TY - JOUR T1 - Changes in the distribution of body mass index among college students in Shandong, China from 1985 to 2005 AN - 1011201724; 14774771 AB - This article analyzes the changes in the distribution of body mass index (BMI) among college students aged 19-22 in Shandong, China from 1985 to 2005. In the past 20 years, the P sub(50) (percentile 50) of BMI increased, from 20.44 kg/m super(2) in 1985 to 21.00 kg/m super(2) in 2005 for males, and from 19.97 kg/m super(2) in 1985 to 20.42 kg/m super(2) in 2005 for females. The proportion of overweight or obese (defined as BMI => 25 kg/m super(2)) increased from 1.35% in 1985 to 7.17% in 2005. Overweight and obesity among college students has become a serious public health problem. Comprehensive evidence-based strategies of intervention should be introduced, including periodic monitoring. JF - Anthropological Science AU - Zhang, Yingxiu AU - Wang, Shurong AD - Shandong Center for Disease Control and Prevention, Jinan Y1 - 2010 PY - 2010 DA - 2010 SP - 123 EP - 127 PB - The Anthropological Society of Nippon VL - 118 IS - 2 SN - 1348-8570, 1348-8570 KW - Physical Education Index KW - Analysis KW - Body mass KW - College students KW - Obesity KW - Public health KW - Strategy KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1011201724?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Anthropological+Science&rft.atitle=Changes+in+the+distribution+of+body+mass+index+among+college+students+in+Shandong%2C+China+from+1985+to+2005&rft.au=Zhang%2C+Yingxiu%3BWang%2C+Shurong&rft.aulast=Zhang&rft.aufirst=Yingxiu&rft.date=2010-01-01&rft.volume=118&rft.issue=2&rft.spage=123&rft.isbn=&rft.btitle=&rft.title=Anthropological+Science&rft.issn=13488570&rft_id=info:doi/10.1537%2Fase.091015 LA - English DB - Physical Education Index N1 - Date revised - 2012-05-01 N1 - Last updated - 2012-06-18 N1 - SubjectsTermNotLitGenreText - Obesity; College students; Analysis; Body mass; Strategy; Public health DO - http://dx.doi.org/10.1537/ase.091015 ER -