TY - JOUR T1 - Investigating nearshore processes at Cape Hatteras, NC AN - 807614606; 2010-097073 AB - Understanding the processes responsible for coastal change is important for managing both our natural and economic coastal resources. The USGS Carolinas Coastal Change Processes Project (http://woodshole.er.usgs.gov/project-pages/cccp/) is investigating the interactions between onshore, nearshore, and offshore sediment transport processes driving coastal change in the Carolinas using geophysical surveys, oceanographic studies, shoreline change analysis, and predictive models. In the coastal zone, storms are one of the primary driving forces resulting in coastal change. Understanding the processes that drive coastal change and understanding how factors such as the underlying geologic framework modify coastal evolution will increase our capability to predict impacts of storms on coastal systems. In spring 2009 we conducted a set of field observations in the offshore region around Diamond Shoals; and in February 2010 we plan a large nearshore field experiment in the Cape Hatteras National Seashore to measure waves and currents in the surfzone. We will deploy oceanographic equipment at 12 sites, radar systems, dye tracers, mount a camera atop the Cape Hatteras Lighthouse, and conduct topographic and bathymetric surveys. The experiment is focusing on how storms drive coastal circulation, how the interaction between the coastline orientation and wave directions drives nearshore flows, how alongshore transport processes deliver sediment to the tip of Cape Hatteras, and investigate the sediment convergence processes that maintain Diamond Shoals. Preliminary results from both experiments will be presented. An understanding of these processes will increase our capability to better understand the complex interactions that occur within and drive changes in our coastal systems. JF - Abstracts with Programs - Geological Society of America AU - Warner, John C AU - List, Jeffrey AU - Thieler, E Robert AU - Voulgaris, George AU - Haas, Kevin AU - McNinch, Jesse AU - Anonymous Y1 - 2010/03// PY - 2010 DA - March 2010 SP - 141 PB - Geological Society of America (GSA), Boulder, CO VL - 42 IS - 1 SN - 0016-7592, 0016-7592 KW - United States KW - currents KW - Northwest Atlantic KW - experimental studies KW - Cape Hatteras KW - surf zones KW - landform evolution KW - sedimentation KW - shorelines KW - nearshore sedimentation KW - national parks KW - Dare County North Carolina KW - public lands KW - ocean currents KW - national seashores KW - ocean waves KW - North Carolina KW - geomorphology KW - North Atlantic KW - Atlantic Ocean KW - field studies KW - Atlantic Coastal Plain KW - 23:Geomorphology KW - 07:Oceanography UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/807614606?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Abstracts+with+Programs+-+Geological+Society+of+America&rft.atitle=Investigating+nearshore+processes+at+Cape+Hatteras%2C+NC&rft.au=Warner%2C+John+C%3BList%2C+Jeffrey%3BThieler%2C+E+Robert%3BVoulgaris%2C+George%3BHaas%2C+Kevin%3BMcNinch%2C+Jesse%3BAnonymous&rft.aulast=Warner&rft.aufirst=John&rft.date=2010-03-01&rft.volume=42&rft.issue=1&rft.spage=141&rft.isbn=&rft.btitle=&rft.title=Abstracts+with+Programs+-+Geological+Society+of+America&rft.issn=00167592&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Geological Society of America, Northeastern Section, 45th annual meeting Geological Society of America, Southeastern Section, 59th annual meeting N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by the Geological Society of America, Boulder, CO, United States N1 - Date revised - 2010-01-01 N1 - PubXState - CO N1 - Last updated - 2012-06-07 N1 - CODEN - GAAPBC N1 - SubjectsTermNotLitGenreText - Atlantic Coastal Plain; Atlantic Ocean; Cape Hatteras; currents; Dare County North Carolina; experimental studies; field studies; geomorphology; landform evolution; national parks; national seashores; nearshore sedimentation; North Atlantic; North Carolina; Northwest Atlantic; ocean currents; ocean waves; public lands; sedimentation; shorelines; surf zones; United States ER - TY - JOUR T1 - Shoreline impacts from mining shoals offshore of Assateague Island National Seashore AN - 762682762; 2010-094525 AB - Wallops Island is a barrier island on Virginia's Eastern Shore and NASA's rocket launch site for Wallops Flight Facility. Because Wallops Island is experiencing chronic beach erosion that threatens the facility's existence, a storm damage reduction program has been designed. The closest available beach fill material for the project has been located in shoals offshore of Assateague Island National Seashore, 10+ miles away. A numerical modeling study was set up to analyze the impact of offshore mining on the wave-induced longshore sediment transport along Assateague Island. The procedure involved the refraction of offshore waves over the existing bathymetry into near-breaking depths. Then, the same offshore waves were refracted over bathymetry that had been modified by an appropriate increase in the depth in three potential borrow areas. All sets of resulting near-breaking waves were used to drive a sediment transport model, and with and without mining results were compared. The mining-induced difference in the sediment transport for each shoal was related to the natural variation in the wave climate to determine if it was significant. Blackfish Bank is the shallowest of the three shoals and the closest to shore. Modeling results showed that removing material from this shoal has shoreline impacts that exceed threshold criteria. The impacts of mining the other two shoals are below threshold criteria. For all the shoal-mining scenarios, the greatest shoreline impacts were found to be in the vicinity of Tom's Cove, a narrow isthmus separating a portion of Chincoteague Bay from the Atlantic Ocean. This is a particularly vulnerable area since repeated surveys have shown this narrow strip of land to be thinning over time, mainly due to erosion of the ocean shoreline. Because of the potential for overwash in this area, possibly leading to new inlet formation, it is important that offshore mining not have significant negative impacts in this area. Because of this analysis, Blackfish Bank has been removed from further consideration as a potential borrow site. In November 2009, after the modeling study was completed, but before offshore mining had occurred, a Nor'easter created the first substantial breach along this section of shoreline. JF - Abstracts with Programs - Geological Society of America AU - King, David B, Jr AU - Anonymous Y1 - 2010/03// PY - 2010 DA - March 2010 SP - 103 PB - Geological Society of America (GSA), Boulder, CO VL - 42 IS - 1 SN - 0016-7592, 0016-7592 KW - United States KW - mining KW - national parks KW - longshore currents KW - Worcester County Maryland KW - transport KW - national seashores KW - sediments KW - Maryland KW - Delmarva Peninsula KW - Accomack County Virginia KW - Atlantic Coastal Plain KW - currents KW - Assateague Island National Seashore KW - sand KW - Northwest Atlantic KW - barrier islands KW - beach nourishment KW - shoals KW - Virginia KW - numerical models KW - sediment transport KW - clastic sediments KW - Chincoteague Bay KW - sedimentation KW - shorelines KW - public lands KW - ocean currents KW - Wallops Island KW - geomorphology KW - North Atlantic KW - coastal sedimentation KW - Atlantic Ocean KW - 30:Engineering geology KW - 23:Geomorphology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/762682762?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Abstracts+with+Programs+-+Geological+Society+of+America&rft.atitle=Shoreline+impacts+from+mining+shoals+offshore+of+Assateague+Island+National+Seashore&rft.au=King%2C+David+B%2C+Jr%3BAnonymous&rft.aulast=King&rft.aufirst=David&rft.date=2010-03-01&rft.volume=42&rft.issue=1&rft.spage=103&rft.isbn=&rft.btitle=&rft.title=Abstracts+with+Programs+-+Geological+Society+of+America&rft.issn=00167592&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Geological Society of America, Northeastern Section, 45th annual meeting Geological Society of America, Southeastern Section, 59th annual meeting N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by the Geological Society of America, Boulder, CO, United States N1 - Date revised - 2010-01-01 N1 - PubXState - CO N1 - Last updated - 2012-06-07 N1 - CODEN - GAAPBC N1 - SubjectsTermNotLitGenreText - Accomack County Virginia; Assateague Island National Seashore; Atlantic Coastal Plain; Atlantic Ocean; barrier islands; beach nourishment; Chincoteague Bay; clastic sediments; coastal sedimentation; currents; Delmarva Peninsula; geomorphology; longshore currents; Maryland; mining; national parks; national seashores; North Atlantic; Northwest Atlantic; numerical models; ocean currents; public lands; sand; sediment transport; sedimentation; sediments; shoals; shorelines; transport; United States; Virginia; Wallops Island; Worcester County Maryland ER - TY - JOUR T1 - Rapamycin protects mice from staphylococcal enterotoxin B-induced toxic shock and blocks cytokine release in vitro and in vivo. AN - 733113616; 20086156 AB - Staphylococcal enterotoxins are potent activators for human T cells and cause lethal toxic shock. Rapamycin, an immunosuppressant, was tested for its ability to inhibit staphylococcal enterotoxin B (SEB)-induced activation of human peripheral blood mononuclear cells (PBMC) in vitro and toxin-mediated shock in mice. Stimulation of PMBC by SEB was effectively blocked by rapamycin as evidenced by the inhibition of tumor necrosis factor alpha (TNF-alpha), interleukin 1beta (IL-1beta), IL-6, IL-2, gamma interferon (IFN-gamma), monocyte chemoattractant protein 1 (MCP-1), macrophage inflammatory protein 1alpha (MIP-1alpha), MIP-1beta, and T-cell proliferation. In vivo, rapamycin protected 100% of mice from lethal shock, even when administered 24 h after intranasal SEB challenge. The serum levels of MCP-1 and IL-6, after intranasal exposure to SEB, were significantly reduced in mice given rapamycin versus controls. Additionally, rapamycin diminished the weight loss and temperature fluctuations elicited by SEB. JF - Antimicrobial agents and chemotherapy AU - Krakauer, Teresa AU - Buckley, Marilyn AU - Issaq, Haleem J AU - Fox, Stephen D AD - Dept. of Immunology, Bldg. 1425, USAMRIID, Fort Detrick, Frederick, MD 21702-5011, USA. teresa.krakauer@amedd.army.mil Y1 - 2010/03// PY - 2010 DA - March 2010 SP - 1125 EP - 1131 VL - 54 IS - 3 KW - Anti-Bacterial Agents KW - 0 KW - Cytokines KW - Enterotoxins KW - enterotoxin B, staphylococcal KW - 39424-53-8 KW - Sirolimus KW - W36ZG6FT64 KW - Index Medicus KW - Lymphocyte Activation -- drug effects KW - Animals KW - Leukocytes, Mononuclear -- chemistry KW - Humans KW - Treatment Outcome KW - Mice, Inbred C3H KW - Mice KW - T-Lymphocytes -- drug effects KW - T-Lymphocytes -- immunology KW - Male KW - Sirolimus -- administration & dosage KW - Enterotoxins -- immunology KW - Shock, Septic -- immunology KW - Shock, Septic -- drug therapy KW - Sirolimus -- pharmacology KW - Anti-Bacterial Agents -- pharmacology KW - Anti-Bacterial Agents -- administration & dosage KW - Cytokines -- antagonists & inhibitors KW - Enterotoxins -- toxicity KW - Shock, Septic -- prevention & control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733113616?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+agents+and+chemotherapy&rft.atitle=Rapamycin+protects+mice+from+staphylococcal+enterotoxin+B-induced+toxic+shock+and+blocks+cytokine+release+in+vitro+and+in+vivo.&rft.au=Krakauer%2C+Teresa%3BBuckley%2C+Marilyn%3BIssaq%2C+Haleem+J%3BFox%2C+Stephen+D&rft.aulast=Krakauer&rft.aufirst=Teresa&rft.date=2010-03-01&rft.volume=54&rft.issue=3&rft.spage=1125&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+agents+and+chemotherapy&rft.issn=1098-6596&rft_id=info:doi/10.1128%2FAAC.01015-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-05-31 N1 - Date created - 2010-02-22 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: JAMA. 1984 Jan 27;251(4):487-9 [6690814] Methods Enzymol. 1988;165:324-33 [3231111] Cell Immunol. 1989 Apr 15;120(1):92-101 [2522832] Proc Natl Acad Sci U S A. 1989 Jun;86(11):4210-4 [2542966] Proc Natl Acad Sci U S A. 1989 Nov;86(22):8941-5 [2479030] Science. 1990 May 11;248(4956):705-11 [2185544] J Immunol. 1991 Jan 15;146(2):463-8 [1987273] Science. 1991 Aug 23;253(5022):905-9 [1715094] J Exp Med. 1992 Jan 1;175(1):91-8 [1730929] J Infect Dis. 1993 May;167(5):997-1002 [8486972] Epidemiol Infect. 1993 Jun;110(3):519-31 [8519317] Adv Immunol. 1993;54:99-166 [8397479] Infect Immun. 1993 Dec;61(12):5333-8 [8225606] Blood. 1994 Jan 15;83(2):600-9 [8286755] Gastroenterology. 1994 Feb;106(2):450-8 [8299910] Eur J Immunol. 1996 May;26(5):1074-82 [8647170] Infect Dis Clin North Am. 1996 Dec;10(4):727-46 [8958166] Eur J Immunol. 1997 Apr;27(4):825-33 [9130631] J Leukoc Biol. 1999 Jul;66(1):158-64 [10411004] Endocrinology. 2005 Mar;146(3):1328-37 [15576463] Infect Immun. 2005 Apr;73(4):2452-60 [15784591] J Pharmacol Exp Ther. 2005 Jun;313(3):952-61 [15769867] Blood. 2005 Jun 15;105(12):4743-8 [15746082] Antimicrob Agents Chemother. 2006 Jan;50(1):391-5 [16377721] Blood. 2006 Feb 1;107(3):1018-23 [16210336] Cell. 2006 Feb 10;124(3):471-84 [16469695] J Immunol. 2007 Jan 1;178(1):320-9 [17182569] Clin Cancer Res. 2007 Apr 1;13(7):2281-9 [17404113] J Exp Med. 2008 Mar 17;205(3):565-74 [18283119] J Biomed Mater Res A. 2008 Jun 15;85(4):983-92 [17907241] J Neurosci. 2008 May 21;28(21):5422-32 [18495876] Mol Cancer Ther. 2009 Jan;8(1):83-93 [19139116] Res Vet Sci. 2009 Apr;86(2):241-7 [18793785] Transplantation. 2009 Apr 27;87(8 Suppl):S1-6 [19384179] Nat Rev Immunol. 2009 May;9(5):324-37 [19390566] Int J Biochem Cell Biol. 2009 Aug-Sep;41(8-9):1708-18 [19433312] Biochem Biophys Res Commun. 2009 Jul 10;384(4):471-5 [19422788] J Infect Dis. 1995 Oct;172(4):988-92 [7561220] Nat Med. 2000 Apr;6(4):414-21 [10742148] Obes Res. 2000 May;8(3):249-54 [10832768] Kidney Int. 2001 Jan;59(1):3-16 [11135052] Infect Immun. 2001 Feb;69(2):875-84 [11159981] Mol Cell Biol. 2001 Aug;21(15):5050-62 [11438661] Annu Rev Microbiol. 2001;55:77-104 [11544350] J Biol Chem. 2001 Sep 28;276(39):36079-82 [11500483] Clin Lab Med. 2001 Sep;21(3):593-605 [11577702] Blood. 2003 Feb 15;101(4):1439-45 [12393532] Transplant Proc. 2003 May;35(3 Suppl):7S-14S [12742462] Clin Exp Immunol. 2003 Sep;133(3):299-306 [12930353] FEBS Lett. 2003 Aug 28;550(1-3):94-100 [12935893] Cancer Biol Ther. 2003 Jul-Aug;2(4 Suppl 1):S169-77 [14508096] Clin Infect Dis. 2004 Mar 15;38(6):836-42 [14999628] Transplantation. 2004 May 15;77(9):1319-26 [15167584] JAMA. 1981 Aug 14;246(7):741-8 [7253137] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1128/AAC.01015-09 ER - TY - JOUR T1 - Activity of Dalbavancin against Bacillus anthracis In Vitro and in a Mouse Inhalation Anthrax Model AN - 21498680; 12495835 AB - Bacillus anthracis, the causative agent of anthrax, can produce fatal disease when it is inhaled or ingested by humans. Dalbavancin, a novel, semisynthetic lipoglycopeptide, has potent activity, greater than that of vancomycin, against Gram-positive bacteria and a half-life in humans that supports once-weekly dosing. Dalbavancin demonstrated potent in vitro activity against B. anthracis (MIC range, 0.03 to 0.5 mg/liter; MIC50 and MIC90, 0.06 and 0.25 mg/liter, respectively), which led us to test its efficacy in a murine inhalation anthrax model. The peak concentrations of dalbavancin in mouse plasma after the administration of single intraperitoneal doses of 5 and 20 mg/kg of body weight were 15 and 71 mg/kg, respectively. At 20 mg/kg, the dalbavancin activity was detectable for 6 days after administration (terminal half-life, 53 h), indicating that long intervals between doses were feasible. The mice were challenged with 50 to 100 times the median lethal dose of the Ames strain of B. anthracis, an inoculum that kills untreated animals within 4 days. The efficacy of dalbavancin was 80 to 100%, as determined by the rate of survival at 42 days, when treatment was initiated 24 h postchallenge with regimens of 15 to 120 mg/kg every 36 h (q36h) or 30 to 240 mg/kg every 72 h (q72h). A regimen of ciprofloxacin known to protect 100% of animals was tested in parallel. Delayed dalbavancin treatment (beginning 36 or 48 h postchallenge) with 60 mg/kg q36h or 120 mg/kg q72h still provided 70 to 100% survival. The low MICs and long duration of efficacy in vivo suggest that dalbavancin may have potential as an alternative treatment or for the prophylaxis of B. anthracis infections. JF - Antimicrobial Agents & Chemotherapy AU - Heine, Henry S AU - Purcell, Bret K AU - Bassett, Jennifer AU - Miller, Lynda AU - Goldstein, Beth P AD - United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, henry.heine@amedd.army.mil Y1 - 2010/03// PY - 2010 DA - Mar 2010 SP - 991 EP - 996 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 54 IS - 3 SN - 0066-4804, 0066-4804 KW - Microbiology Abstracts B: Bacteriology; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Inhalation KW - Gram-positive bacteria KW - Animal models KW - Survival KW - Bacillus anthracis KW - Infection KW - Minimum inhibitory concentration KW - Ciprofloxacin KW - Body weight KW - Inoculum KW - Prophylaxis KW - Vancomycin KW - Anthrax KW - Lethal dose KW - A 01340:Antibiotics & Antimicrobials KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21498680?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Activity+of+Dalbavancin+against+Bacillus+anthracis+In+Vitro+and+in+a+Mouse+Inhalation+Anthrax+Model&rft.au=Heine%2C+Henry+S%3BPurcell%2C+Bret+K%3BBassett%2C+Jennifer%3BMiller%2C+Lynda%3BGoldstein%2C+Beth+P&rft.aulast=Heine&rft.aufirst=Henry&rft.date=2010-03-01&rft.volume=54&rft.issue=3&rft.spage=991&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.00820-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Inhalation; Gram-positive bacteria; Animal models; Survival; Infection; Minimum inhibitory concentration; Ciprofloxacin; Body weight; Prophylaxis; Inoculum; Anthrax; Vancomycin; Lethal dose; Bacillus anthracis DO - http://dx.doi.org/10.1128/AAC.00820-09 ER - TY - JOUR T1 - Identification of Pathogenic Vibrio Species by Multilocus PCR-Electrospray Ionization Mass Spectrometry and Its Application to Aquatic Environments of the Former Soviet Republic of Georgia , AN - 21283424; 12496192 AB - The Ibis T5000 is a novel diagnostic platform that couples PCR and mass spectrometry. In this study, we developed an assay that can identify all known pathogenic Vibrio species and field-tested it using natural water samples from both freshwater lakes and the Georgian coastal zone of the Black Sea. Of the 278 total water samples screened, 9 different Vibrio species were detected, 114 (41%) samples were positive for V. cholerae, and 5 (0.8%) samples were positive for the cholera toxin A gene (ctxA). All ctxA-positive samples were from two freshwater lakes, and no ctxA-positive samples from any of the Black Sea sites were detected. JF - Applied and Environmental Microbiology AU - Whitehouse, Chris A AU - Baldwin, Carson AU - Sampath, Rangarajan AU - Blyn, Lawrence B AU - Melton, Rachael AU - Li, Feng AU - Hall, Thomas A AU - Harpin, Vanessa AU - Matthews, Heather AU - Tediashvili, Marina AU - Jaiani, Ekaterina AU - Kokashvili, Tamar AU - Janelidze, Nino AU - Grim, Christopher AU - Colwell, Rita R AU - Huq, Anwar AD - Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, chris.whitehouse@us.army.mil chris.whitehouse@us.army.mil chris.whitehouse@us.army.mil chris.whitehouse@us.army.mil chris.whitehouse@us.army.mil chris.whitehouse@us.army.mil chris.whitehouse@us.army.mil Y1 - 2010/03// PY - 2010 DA - March 2010 SP - 1996 EP - 2001 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 76 IS - 6 SN - 0099-2240, 0099-2240 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; ASFA 3: Aquatic Pollution & Environmental Quality; Microbiology Abstracts B: Bacteriology; Oceanic Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA Marine Biotechnology Abstracts KW - Pathogenic bacteria KW - Freshwater lakes KW - Toxicants KW - Freshwater environments KW - Nucleotide sequence KW - Bacterial diseases KW - Freshwater KW - Aquatic environment KW - Mass spectroscopy KW - MED, Black Sea KW - Vibrio KW - Lakes KW - Coastal zone KW - Cholera toxin KW - Microbiology KW - DNA KW - Polymerase chain reaction KW - Georgia KW - Disease detection KW - A 01340:Antibiotics & Antimicrobials KW - Q4 27740:Products KW - O 1010:Viruses, Bacteria, Protists, Fungi and Plants KW - Q1 08484:Species interactions: parasites and diseases KW - Q5 08524:Public health, medicines, dangerous organisms KW - J 02450:Ecology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21283424?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+and+Environmental+Microbiology&rft.atitle=Identification+of+Pathogenic+Vibrio+Species+by+Multilocus+PCR-Electrospray+Ionization+Mass+Spectrometry+and+Its+Application+to+Aquatic+Environments+of+the+Former+Soviet+Republic+of+Georgia+%2C&rft.au=Whitehouse%2C+Chris+A%3BBaldwin%2C+Carson%3BSampath%2C+Rangarajan%3BBlyn%2C+Lawrence+B%3BMelton%2C+Rachael%3BLi%2C+Feng%3BHall%2C+Thomas+A%3BHarpin%2C+Vanessa%3BMatthews%2C+Heather%3BTediashvili%2C+Marina%3BJaiani%2C+Ekaterina%3BKokashvili%2C+Tamar%3BJanelidze%2C+Nino%3BGrim%2C+Christopher%3BColwell%2C+Rita+R%3BHuq%2C+Anwar&rft.aulast=Whitehouse&rft.aufirst=Chris&rft.date=2010-03-01&rft.volume=76&rft.issue=6&rft.spage=1996&rft.isbn=&rft.btitle=&rft.title=Applied+and+Environmental+Microbiology&rft.issn=00992240&rft_id=info:doi/10.1128%2FAEM.01919-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Toxicants; Freshwater lakes; Pathogenic bacteria; Nucleotide sequence; Microbiology; Bacterial diseases; DNA; Polymerase chain reaction; Disease detection; Mass spectroscopy; Coastal zone; Lakes; Cholera toxin; Freshwater environments; Aquatic environment; Vibrio; MED, Black Sea; Georgia; Freshwater DO - http://dx.doi.org/10.1128/AEM.01919-09 ER - TY - CPAPER T1 - On the Performance Improvement of 3-D Finite Element Code Modeling Water Flows T2 - 2010 SIAM Conference on Parallel Processing and Scientific Computing (PP10) AN - 42342493; 5656649 JF - 2010 SIAM Conference on Parallel Processing and Scientific Computing (PP10) AU - Cheng, Jing-Ru AU - Nguyen, Hung AU - Eller, Paul AU - Maier, Robert Y1 - 2010/02/24/ PY - 2010 DA - 2010 Feb 24 KW - Water flow KW - Stream flow KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42342493?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2010+SIAM+Conference+on+Parallel+Processing+and+Scientific+Computing+%28PP10%29&rft.atitle=On+the+Performance+Improvement+of+3-D+Finite+Element+Code+Modeling+Water+Flows&rft.au=Cheng%2C+Jing-Ru%3BNguyen%2C+Hung%3BEller%2C+Paul%3BMaier%2C+Robert&rft.aulast=Cheng&rft.aufirst=Jing-Ru&rft.date=2010-02-24&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2010+SIAM+Conference+on+Parallel+Processing+and+Scientific+Computing+%28PP10%29&rft.issn=&rft_id=info:doi/ L2 - http://meetings.siam.org/program.cfm?CONFCODE=PP10 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Characterization of a Large-Particle Generation System in a Nonhuman Primate Head-Only Exposure Chamber T2 - 8th ASM Biodefense and Emerging Diseases Research Meeting AN - 42348012; 5658574 JF - 8th ASM Biodefense and Emerging Diseases Research Meeting AU - Yeager, J AU - Kline, J AU - Dabisch, P Y1 - 2010/02/21/ PY - 2010 DA - 2010 Feb 21 KW - Primates KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42348012?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=8th+ASM+Biodefense+and+Emerging+Diseases+Research+Meeting&rft.atitle=Characterization+of+a+Large-Particle+Generation+System+in+a+Nonhuman+Primate+Head-Only+Exposure+Chamber&rft.au=Yeager%2C+J%3BKline%2C+J%3BDabisch%2C+P&rft.aulast=Yeager&rft.aufirst=J&rft.date=2010-02-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=8th+ASM+Biodefense+and+Emerging+Diseases+Research+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.asmbiodefense.org/images/stories/scientific_section_proof_3 .pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Engineering Subtilisin Proteases to Specifically Cleave Bacterial Toxins T2 - 8th ASM Biodefense and Emerging Diseases Research Meeting AN - 42344072; 5658493 JF - 8th ASM Biodefense and Emerging Diseases Research Meeting AU - Buckwalter-Crist, T AU - Stiles, B AU - Hale, M L AU - Ahmed, S A AU - Hines, H AU - Rozak, D A AU - Bryan, P AU - Purcell, B Y1 - 2010/02/21/ PY - 2010 DA - 2010 Feb 21 KW - Toxins KW - Subtilisin KW - Proteinase KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42344072?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=8th+ASM+Biodefense+and+Emerging+Diseases+Research+Meeting&rft.atitle=Engineering+Subtilisin+Proteases+to+Specifically+Cleave+Bacterial+Toxins&rft.au=Buckwalter-Crist%2C+T%3BStiles%2C+B%3BHale%2C+M+L%3BAhmed%2C+S+A%3BHines%2C+H%3BRozak%2C+D+A%3BBryan%2C+P%3BPurcell%2C+B&rft.aulast=Buckwalter-Crist&rft.aufirst=T&rft.date=2010-02-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=8th+ASM+Biodefense+and+Emerging+Diseases+Research+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.asmbiodefense.org/images/stories/scientific_section_proof_3 .pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Rapid Identification of Vector-Borne Flaviviruses Using PCR/Mass Spectrometry T2 - 8th ASM Biodefense and Emerging Diseases Research Meeting AN - 42343111; 5658656 JF - 8th ASM Biodefense and Emerging Diseases Research Meeting AU - Whitehouse, C A AU - Lovari, R AU - Grant, R J AU - Blyn, L B AU - Baldwin, C D AU - Eshoo, M W AU - Turrell, M J AU - Sampath, R AU - Rossi, C AU - Li, F. Y1 - 2010/02/21/ PY - 2010 DA - 2010 Feb 21 KW - Mass spectroscopy KW - Polymerase chain reaction KW - Nucleotide sequence KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42343111?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=8th+ASM+Biodefense+and+Emerging+Diseases+Research+Meeting&rft.atitle=Rapid+Identification+of+Vector-Borne+Flaviviruses+Using+PCR%2FMass+Spectrometry&rft.au=Whitehouse%2C+C+A%3BLovari%2C+R%3BGrant%2C+R+J%3BBlyn%2C+L+B%3BBaldwin%2C+C+D%3BEshoo%2C+M+W%3BTurrell%2C+M+J%3BSampath%2C+R%3BRossi%2C+C%3BLi%2C+F.&rft.aulast=Whitehouse&rft.aufirst=C&rft.date=2010-02-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=8th+ASM+Biodefense+and+Emerging+Diseases+Research+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.asmbiodefense.org/images/stories/scientific_section_proof_3 .pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Characterization of the Syrian Hamster (Mesocricetus auratus) as an Animal Model for Aerosolized Equine Viral Encephalitis Diseases T2 - 8th ASM Biodefense and Emerging Diseases Research Meeting AN - 42340231; 5658618 JF - 8th ASM Biodefense and Emerging Diseases Research Meeting AU - Erwin-Cohen, R AU - Porter, A I AU - Bakken, R R AU - Fisher, D E AU - Glass, P J AU - Parker, M D Y1 - 2010/02/21/ PY - 2010 DA - 2010 Feb 21 KW - Animal models KW - Encephalitis KW - Mesocricetus auratus KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42340231?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=8th+ASM+Biodefense+and+Emerging+Diseases+Research+Meeting&rft.atitle=Characterization+of+the+Syrian+Hamster+%28Mesocricetus+auratus%29+as+an+Animal+Model+for+Aerosolized+Equine+Viral+Encephalitis+Diseases&rft.au=Erwin-Cohen%2C+R%3BPorter%2C+A+I%3BBakken%2C+R+R%3BFisher%2C+D+E%3BGlass%2C+P+J%3BParker%2C+M+D&rft.aulast=Erwin-Cohen&rft.aufirst=R&rft.date=2010-02-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=8th+ASM+Biodefense+and+Emerging+Diseases+Research+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.asmbiodefense.org/images/stories/scientific_section_proof_3 .pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - PCR Inhibition Associated with Exterior Aerosols of the Western United States T2 - 8th ASM Biodefense and Emerging Diseases Research Meeting AN - 42339191; 5658663 JF - 8th ASM Biodefense and Emerging Diseases Research Meeting AU - Calomiris, J J Y1 - 2010/02/21/ PY - 2010 DA - 2010 Feb 21 KW - USA KW - Aerosols KW - Polymerase chain reaction KW - Nucleotide sequence KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42339191?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=8th+ASM+Biodefense+and+Emerging+Diseases+Research+Meeting&rft.atitle=PCR+Inhibition+Associated+with+Exterior+Aerosols+of+the+Western+United+States&rft.au=Calomiris%2C+J+J&rft.aulast=Calomiris&rft.aufirst=J&rft.date=2010-02-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=8th+ASM+Biodefense+and+Emerging+Diseases+Research+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.asmbiodefense.org/images/stories/scientific_section_proof_3 .pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Mediation in the Military Workplace T2 - Thirteenth Annual Meeting of the The American Association of Behavioral and Social Sciences AN - 42327607; 5646187 JF - Thirteenth Annual Meeting of the The American Association of Behavioral and Social Sciences AU - Robers, Brandon Y1 - 2010/02/04/ PY - 2010 DA - 2010 Feb 04 KW - Military KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42327607?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Thirteenth+Annual+Meeting+of+the+The+American+Association+of+Behavioral+and+Social+Sciences&rft.atitle=Mediation+in+the+Military+Workplace&rft.au=Robers%2C+Brandon&rft.aulast=Robers&rft.aufirst=Brandon&rft.date=2010-02-04&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Thirteenth+Annual+Meeting+of+the+The+American+Association+of+Behavioral+and+Social+Sciences&rft.issn=&rft_id=info:doi/ L2 - http://aabss.org/PreliminaryProgram/PreliminaryProgram2010.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Disclosure of Emotional Events in Groups at Risk for Posttraumatic Stress Disorder AN - 907189751; 16049726 AB - The disclosure of emotional events to various social intimates (disclosure targets) was measured in 2 samples (soldiers and first responders) at risk for posttraumatic stress disorder (PTSD), as well as a comparison sample of college students. These 3 groups completed survey measures of disclosure, and at risk groups also completed measures of PTSD symptoms and social support. Groups at risk for PTSD were less likely to disclose emotions related to potentially traumatic events than were college students reporting general emotional disclosure. Overall, disclosure of positive emotions was more likely than disclosure of negative emotions. Furthermore, amount of disclosure depended on the person to whom the individual disclosed. Within groups at risk for PTSD, social support was associated with lower levels of PTSD. However, this relationship was mediated by emotional disclosure to each target. Disclosure of positive emotions generally was associated with lower levels of PTSD, and disclosure of negative emotions to those with similar at-risk status was associated with greater levels of PTSD. JF - International Journal of Stress Management AU - Hoyt, Tim AU - Pasupathi, Monisha AU - Smith, Bruce W AU - Yeater, Elizabeth A AU - Kay, Virginia S AU - Tooley, Erin AD - Department of Psychology, University of New Mexico, Albuquerque, timothy.hoyt1@us.army.mil Y1 - 2010/02// PY - 2010 DA - Feb 2010 SP - 78 EP - 95 PB - American Psychological Association VL - 17 IS - 1 SN - 1072-5245, 1072-5245 KW - Risk Abstracts; Health & Safety Science Abstracts KW - posttraumatic stress disorder KW - Psychology KW - colleges and universities KW - Stress KW - Military KW - H 0500:General KW - R2 23110:Psychological aspects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/907189751?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Stress+Management&rft.atitle=Disclosure+of+Emotional+Events+in+Groups+at+Risk+for+Posttraumatic+Stress+Disorder&rft.au=Hoyt%2C+Tim%3BPasupathi%2C+Monisha%3BSmith%2C+Bruce+W%3BYeater%2C+Elizabeth+A%3BKay%2C+Virginia+S%3BTooley%2C+Erin&rft.aulast=Hoyt&rft.aufirst=Tim&rft.date=2010-02-01&rft.volume=17&rft.issue=1&rft.spage=78&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Stress+Management&rft.issn=10725245&rft_id=info:doi/10.1037%2Fa0017453 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - posttraumatic stress disorder; Psychology; colleges and universities; Stress; Military DO - http://dx.doi.org/10.1037/a0017453 ER - TY - JOUR T1 - River stage response to alteration of Upper Mississippi River channels, floodplains, and watersheds AN - 860391104; 14393435 AB - The Upper Mississippi River System (UMRS) is a large and diverse river system that changes character along its 1,200 mile network of rivers and canals and 2.6 million acres of floodplain. It supports more than 30 million people in its watershed, a significant commercial waterway, more than a million acres of "floodplain" agriculture and about one-half million acres of river-floodplain managed for fish, wildlife, and recreation. Large-scale geomorphology and climate patterns largely determine the hydrologic characteristics of a nested hierarchy of UMRS river reaches. The human impacts above are also important drivers determining hydrologic characteristics within the hierarchy. Understanding the relationship among physical and chemical processes and ecological responses is critical to implement an adaptive management framework for UMRS ecosystem sustainability. Historic or contemporary data from 42 locations were used to examine changes in UMRS hydrology and to demonstrate the utility of a multiple reference condition analysis for river restoration. A multivariate mathematical framework was used to show how river stage hydrology can be characterized by the variability, predictability, seasonality, and rate of change. Large-scale "geomorphic reaches" have distinct hydrologic characteristics and response to development throughout the UMRS region, but within navigation pool hydrology is similar among all impounded reaches regardless of geomorphic reach. Reaches with hydrologic characteristics similar to historic reference conditions should be examined to determine whether those characteristics support desired management objectives. Water levels can be managed, within limits to support navigation and agriculture, to more closely resemble natural hydrology for the benefit of a variety of species, habitats, and ecological processes. JF - Hydrobiologia AU - Theiling, Charles H AU - Nestler, John M AD - U.S. Army Corps of Engineers, Rock Island District, Clock Tower Bldg, P.O. Box 2004, Rock Island, IL, 61204-2004, USA Y1 - 2010/02// PY - 2010 DA - Feb 2010 SP - 17 EP - 47 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 640 IS - 1 SN - 0018-8158, 0018-8158 KW - Ecology Abstracts; Sustainability Science Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Water Resources Abstracts; Aqualine Abstracts; ASFA 1: Biological Sciences & Living Resources KW - Historical account KW - Resource management KW - Freshwater KW - Watersheds KW - Water levels KW - Geomorphology KW - adaptive management KW - Hydrology KW - Seasonal variations KW - Rivers KW - Fluvial morphology KW - Wildlife KW - River discharge KW - Environmental impact KW - Navigation KW - Habitat KW - Flood Plains KW - Channels KW - Canals KW - Recreation KW - navigation KW - Habitat improvement KW - Agriculture KW - River Systems KW - flood plains KW - Human impact KW - Data processing KW - Climate KW - Flood plains KW - geomorphology KW - AQ 00001:Water Resources and Supplies KW - SW 4070:Ecological impact of water development KW - Q1 08463:Habitat community studies KW - Q2 09123:Conservation KW - M3 1010:Issues in Sustainable Development KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/860391104?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Hydrobiologia&rft.atitle=River+stage+response+to+alteration+of+Upper+Mississippi+River+channels%2C+floodplains%2C+and+watersheds&rft.au=Theiling%2C+Charles+H%3BNestler%2C+John+M&rft.aulast=Theiling&rft.aufirst=Charles&rft.date=2010-02-01&rft.volume=640&rft.issue=1&rft.spage=17&rft.isbn=&rft.btitle=&rft.title=Hydrobiologia&rft.issn=00188158&rft_id=info:doi/10.1007%2Fs10750-009-0066-5 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-04-01 N1 - Last updated - 2014-05-02 N1 - SubjectsTermNotLitGenreText - Fluvial morphology; Resource management; Flood plains; Geomorphology; Habitat improvement; Environmental impact; River discharge; Hydrology; Watersheds; Rivers; Agriculture; Data processing; Climate; Wildlife; Habitat; Human impact; Water levels; Canals; Recreation; Seasonal variations; Channels; Historical account; adaptive management; navigation; geomorphology; flood plains; Flood Plains; River Systems; Navigation; Freshwater DO - http://dx.doi.org/10.1007/s10750-009-0066-5 ER - TY - JOUR T1 - Sediment toxicity and bioaccumulation of nano and micron-sized aluminum oxide AN - 858421823; 14430102 AB - Nano-aluminum oxide (Al sub(2)O sub(3)) is used commercially in coatings and abrasives. Nano-Al sub(2)O sub(3) can also be generated through the oxidation of nano-aluminum in military propellants and energetics. The purpose of the present study was to assess toxicity and bioaccumulation of nano-Al sub(2)O sub(3) to a variety of sediment organisms (Tubifex tubifex, Hyalella azteca, Lumbriculus variegatus, and Corbicula fluminea). The bioaccumulation and toxicity of nano-Al sub(2)O sub(3) was compared with that of micron-sized Al sub(2)O sub(3) to investigate potential size-related effects. Results of the present study show species-specific differences in relative bioaccumulation of nano and micron-sized Al sub(2)O sub(3). Significant toxic effects (survival and growth) were observed in H. azteca testing, but only at high concentrations unlikely to be found in the environment. Nano-Al sub(2)O sub(3) was found to be more toxic than micron-sized Al sub(2)O sub(3) to H. azteca survival in a 14-d study in which organisms were in direct contact with a thin layer of 625 or 2,500 mg of Al sub(2)O sub(3) dispersed on the surface of either sediment or sand. A significant growth effect was also observed for nano but not micron-sized Al sub(2)O sub(3) at the highest treatment level tested (100 g/kg Al sub(2)O sub(3)) in a 10-d H. azteca bioassay in which Al sub(2)O sub(3) was homogenized with sediment. However, differences in measured sediment Al concentrations (micron-sized = 55.1 [+/-0.6] g/kg Al; nano-sized = 66.2 [+/-0.6] g/kg Al) in the nano and micron-sized Al sub(2)O sub(3) preclude direct comparison of the toxicity of these two treatments based on particle size. JF - Environmental Toxicology and Chemistry AU - Stanley, Jacob K AU - Coleman, Jessica G AU - Weiss, Charles A AU - Steevens, Jeffery A AD - U.S. Army Engineer Research and Development Center, Environmental Laboratory, 3909 Halls Ferry Road, Vicksburg, Mississippi 39180, jacob.k.stanley@us.army.mil Y1 - 2010/02/01/ PY - 2010 DA - 2010 Feb 01 SP - 422 EP - 429 PB - Allen Press, Inc., 810 East Tenth St. Lawrence KS 66044 USA VL - 29 IS - 2 SN - 1552-8618, 1552-8618 KW - Risk Abstracts; Environment Abstracts; Toxicology Abstracts KW - Nano KW - Aluminum oxide KW - Sediment KW - Toxicity KW - Bioaccumulation KW - Particle size KW - Propellants KW - Survival KW - Sediments KW - Hyalella azteca KW - Lumbriculus variegatus KW - Bioassays KW - Sand KW - Oxidation KW - Corbicula fluminea KW - oxides KW - survival KW - Military KW - aluminum oxide KW - Tubifex tubifex KW - Coatings KW - X 24360:Metals KW - R2 23050:Environment KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/858421823?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Toxicology+and+Chemistry&rft.atitle=Sediment+toxicity+and+bioaccumulation+of+nano+and+micron-sized+aluminum+oxide&rft.au=Stanley%2C+Jacob+K%3BColeman%2C+Jessica+G%3BWeiss%2C+Charles+A%3BSteevens%2C+Jeffery+A&rft.aulast=Stanley&rft.aufirst=Jacob&rft.date=2010-02-01&rft.volume=29&rft.issue=2&rft.spage=422&rft.isbn=&rft.btitle=&rft.title=Environmental+Toxicology+and+Chemistry&rft.issn=15528618&rft_id=info:doi/10.1002%2Fetc.52 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-03-01 N1 - Last updated - 2015-04-09 N1 - SubjectsTermNotLitGenreText - Particle size; Bioaccumulation; Sand; Oxidation; oxides; Survival; Toxicity; aluminum oxide; Sediments; Coatings; Bioassays; Propellants; Military; survival; Hyalella azteca; Lumbriculus variegatus; Corbicula fluminea; Tubifex tubifex DO - http://dx.doi.org/10.1002/etc.52 ER - TY - JOUR T1 - Variability in the paleoecological record of sediment cores in the Chesapeake Bay due to location AN - 818639588; 2011-006162 AB - Biological and geochemical indicators of changes in climate and land use are reflected differently in sediment cores in the Chesapeake Bay depending on the location of the cores. Pollen and seed records from cores in three different tributaries show synchronous changes in the flora due to climate change throughout the Holocene, but the floras differ for each time interval, depending on the soil substrate of the forests from which the pollen and seeds originated. Climate changes are thus superimposed on the soil template which governs the distribution of terrestrial plant species. Likewise, land use is reflected in geochemical constituents of cores differently, depending on the location of the core with respect to its position in the Bay, whether at the mouth of a tributary in the upper Bay or closer to the ocean. Geochemical records (total organic carbon, total nitrogen, total phosphorus, total sulfur and carbon and nitrogen stable isotopes) of two cores, one largely influenced by the Chester and Susquehanna Rivers and the other in the main stem above the Patuxent River, changed simultaneously but differently in response to similar changes in land use. The records of these cores demonstrate how biological and geochemical indicators can be used not only to infer temporal changes but also to interpret local influences of soil substrate, tidal influence and position within the estuary. JF - Abstracts with Programs - Geological Society of America AU - Sowers, Angela AU - Brush, Grace S AU - Anonymous Y1 - 2010/02// PY - 2010 DA - February 2010 SP - 177 PB - Geological Society of America (GSA), Boulder, CO VL - 42 IS - 1 SN - 0016-7592, 0016-7592 KW - United States KW - Chesapeake Bay KW - terrestrial environment KW - vegetation KW - Holocene KW - cores KW - paleoecology KW - Cenozoic KW - marine sediments KW - pollen KW - sediments KW - miospores KW - seeds KW - Maryland KW - estuarine environment KW - Susquehanna River KW - Atlantic Coastal Plain KW - Quaternary KW - Chester River KW - tributaries KW - palynomorphs KW - Patuxent River KW - microfossils KW - land use KW - 24:Quaternary geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/818639588?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Abstracts+with+Programs+-+Geological+Society+of+America&rft.atitle=Variability+in+the+paleoecological+record+of+sediment+cores+in+the+Chesapeake+Bay+due+to+location&rft.au=Sowers%2C+Angela%3BBrush%2C+Grace+S%3BAnonymous&rft.aulast=Sowers&rft.aufirst=Angela&rft.date=2010-02-01&rft.volume=42&rft.issue=1&rft.spage=177&rft.isbn=&rft.btitle=&rft.title=Abstracts+with+Programs+-+Geological+Society+of+America&rft.issn=00167592&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Geological Society of America, Northeastern Section, 45th annual meeting; Geological Society of America, Southeastern Section, 59th annual meeting N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by the Geological Society of America, Boulder, CO, United States N1 - Date revised - 2011-01-01 N1 - PubXState - CO N1 - Last updated - 2012-06-07 N1 - CODEN - GAAPBC N1 - SubjectsTermNotLitGenreText - Atlantic Coastal Plain; Cenozoic; Chesapeake Bay; Chester River; cores; estuarine environment; Holocene; land use; marine sediments; Maryland; microfossils; miospores; paleoecology; palynomorphs; Patuxent River; pollen; Quaternary; sediments; seeds; Susquehanna River; terrestrial environment; tributaries; United States; vegetation ER - TY - JOUR T1 - Feasibility study for the rapid screening of target molecules using translational diffusion coefficients: diffusion-ordered NMR spectroscopy of biological toxins AN - 754551599; 13313459 AB - A panel of 15 biological toxins ranging between ~60--28,000 g/mol was used to evaluate the feasibility of screening aqueous samples for toxin analytes based on their translational diffusion coefficients, D t. Toxin D t values were measured by pulsed-field gradient H NMR spectroscopy using a bipolar pulse pair, longitudinal eddy current delay pulse sequence incorporating water suppression to achieve the maximum dynamic range for toxin signals. To collect data for an effective screening protocol, reference D t values were determined from five independent measurements at both 25 and 37 C for all toxins in the panel. In the protocol, D t values are measured at both temperatures for a suspected toxin target in a sample, and for assignment as a potential toxin analyte, the measurements are required to fall within c0.25X10cm/s of both reference D t values for at least one toxin in the panel. Only solution viscosity was found to influence sample D t measurements appreciably; however, the measurements are easily corrected for viscosity effects by calculating the D t value of the suspected toxin at infinite dilution. In conclusion, the protocol provides a rapid and effective means for screening aqueous samples for all toxins in the panel, narrowing toxin identification to <=2 possibilities in virtually all cases. JF - Analytical and Bioanalytical Chemistry AU - Henderson, Terry J AD - Biophysical Chemistry Branch, Edgewood Chemical Biological Center, RDCB-DRB-C, 5183 Blackhawk Road, Aberdeen Proving Ground, MD 21010-5424, USA, terry.j.henderson@us.army.mil Y1 - 2010/02// PY - 2010 DA - Feb 2010 SP - 1465 EP - 1471 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 396 IS - 4 SN - 1618-2642, 1618-2642 KW - Toxicology Abstracts KW - Translation KW - Viscosity KW - Data processing KW - Magnetic resonance spectroscopy KW - Temperature requirements KW - Diffusion coefficient KW - Toxins KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754551599?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytical+and+Bioanalytical+Chemistry&rft.atitle=Feasibility+study+for+the+rapid+screening+of+target+molecules+using+translational+diffusion+coefficients%3A+diffusion-ordered+NMR+spectroscopy+of+biological+toxins&rft.au=Henderson%2C+Terry+J&rft.aulast=Henderson&rft.aufirst=Terry&rft.date=2010-02-01&rft.volume=396&rft.issue=4&rft.spage=1465&rft.isbn=&rft.btitle=&rft.title=Analytical+and+Bioanalytical+Chemistry&rft.issn=16182642&rft_id=info:doi/10.1007%2Fs00216-009-3349-9 L2 - http://www.springerlink.com/content/tw112h8984338407/?p=989010a2fd064d41bd177e05e24d1a62&pi=11 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Translation; Data processing; Viscosity; Magnetic resonance spectroscopy; Temperature requirements; Diffusion coefficient; Toxins DO - http://dx.doi.org/10.1007/s00216-009-3349-9 ER - TY - JOUR T1 - Improvements in physical wellbeing over the first two years on antiretroviral therapy in western Kenya AN - 753837859; 3997187 AB - Improvements in physical wellbeing during the first six months on antiretroviral therapy (ART) are well known, but little is known regarding long-term follow-up. We conducted a prospective cohort study among 222 HIV-positive adult tea plantation workers in western Kenya to assess wellbeing over their first two years on ART. Study subjects completed a standardized questionnaire during repeat ART clinic visits. A 30-day recall period was used to elicit the number of days when subjects experienced poor health and the number of days that pain made it difficult to complete usual activities at home and work. A seven-day recall period was used to assess the severity of bodily pain, nausea, fatigue, and rash. Prevalence of most symptoms declined over time. A median of seven days poor health during the first month on ART declined to three days in the 24th month (p=0.043). For pain making usual activities difficult, a median of seven days during the first month on ART fell to zero by 12 months (p≤0.0001) but increased to three days by two years. Any bodily pain (range 59-83%) and fatigue (range 51-84%) over the past seven days were common through two years. However, pain and fatigue often over the past seven days declined over two years (from 24-10% (p=0.067) and 41-15% (p=0.002)). Skin rash was rare at all times, though higher at two years (8.6%) than any other time. Initial improvements in physical wellbeing were sustained over two years, however, increased pain and skin rash at year two may indicate problems as treatment programs mature. These improvements in physical wellbeing will be important in sustaining the long-term success of HIV treatment programs. Reprinted by permission of Routledge, Taylor & Francis Ltd. JF - AIDS care AU - Fox, Matthew AU - McCoy, Kelly AU - Larson, Bruce AU - Rosen, Sydney AU - Bii, Margaret AU - Sigei, Carolyne AU - Shaffer, Douglas AU - Sawe, Fred AU - Wasunna, Monique AU - Simon, Jonathon AD - Boston University ; Kenya Medical Research Institute ; United States Army Medical Research Unit, Nairobi Y1 - 2010/02// PY - 2010 DA - Feb 2010 SP - 137 EP - 145 VL - 22 IS - 2 SN - 0954-0121, 0954-0121 KW - Sociology KW - Medical care KW - Health care KW - AIDS KW - Well-being KW - Africa KW - Pharmaceuticals KW - Medical treatment KW - HIV UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/753837859?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=AIDS+care&rft.atitle=Improvements+in+physical+wellbeing+over+the+first+two+years+on+antiretroviral+therapy+in+western+Kenya&rft.au=Fox%2C+Matthew%3BMcCoy%2C+Kelly%3BLarson%2C+Bruce%3BRosen%2C+Sydney%3BBii%2C+Margaret%3BSigei%2C+Carolyne%3BShaffer%2C+Douglas%3BSawe%2C+Fred%3BWasunna%2C+Monique%3BSimon%2C+Jonathon&rft.aulast=Fox&rft.aufirst=Matthew&rft.date=2010-02-01&rft.volume=22&rft.issue=2&rft.spage=137&rft.isbn=&rft.btitle=&rft.title=AIDS+care&rft.issn=09540121&rft_id=info:doi/10.1080%2F09540120903038366 LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 5703 3617 6220; 13530 13521; 482 3617 6220; 7890 5792 10484; 7875 5775 13521; 5775 13521; 9474; 2 DO - http://dx.doi.org/10.1080/09540120903038366 ER - TY - JOUR T1 - Effect of surface modification on the optical properties of nanocrystalline zinc oxide materials AN - 753746508; 12989132 AB - The wide band gap and unique photoluminescence (PL) spectrum of nanocrystalline zinc oxide (nano-ZnO) make it useful for a variety of photonics and sensor applications. Toward the goal of modifying the electronic structure and optical properties of nano-ZnO, nanorods were functionalized with electron withdrawing organosilanes, 1H,1H,2H,2H-perfluorodecyltriethoxysilane (PFDS) and pentafluorophenyltriethoxysilane (PFS), and a partially conjugated heterobifunctional molecule, p-maleimidophenyl isothiocyanate (PMPI). Fourier transform infrared (FTIR) spectroscopy and x-ray photoelectron spectroscopy (XPS) confirmed the presence of the modifiers on the nano-ZnO surface and verified covalent attachment. PL spectroscopy was performed to evaluate the influence of the modifiers on the nano-ZnO inherent optical behavior. An increase in the nano-ZnO near-band edge emission (UV) was evident for the organosilane modifiers, despite their differing electronic structures, while the defect emission (visible) remained unchanged. However, surface modification with the non-silane modifier PMPI resulted in unaltered UV and visible emission intensity. The varying influence of the modifiers may be due to the absence of a silane group in the PMPI, allowing for more efficient electron transport to the modifier. The influence of size/shape of the nanocrystalline ZnO was also examined by reacting spherical nanoparticles with PFDS. Preliminary results indicate that PFDS modification of the nanospheres resulted in similar PL behavior as the nanorods; although, the inherent PL of the spheres differs from the nanorods. These studies will elucidate the role of modifier structure on surface-modified nano-ZnO optical behavior, so that optical tailoring of the nano-ZnO inherent PL can be realized. JF - Proceedings of SPIE - The International Society for Optical Engineering AU - Soares, Jason W AU - Steeves, Diane M AU - Singh, Jagdeep AU - Im, Jisun AU - Whitten, James E AD - U.S. Army Natick Soldier Research, Development & Engineering Ctr. (USA) Y1 - 2010/02// PY - 2010 DA - Feb 2010 PB - SPIE, P.O. BOX 10 Bellingham WA 98227-0010 United States of America VL - 7603 SN - 0277-786X, 0277-786X KW - Solid State and Superconductivity Abstracts (SO); Environmental Engineering Abstracts (EN); Electronics and Communications Abstracts (EA) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/753746508?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvironmentalengabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Proceedings+of+SPIE+-+The+International+Society+for+Optical+Engineering&rft.atitle=Effect+of+surface+modification+on+the+optical+properties+of+nanocrystalline+zinc+oxide+materials&rft.au=Soares%2C+Jason+W%3BSteeves%2C+Diane+M%3BSingh%2C+Jagdeep%3BIm%2C+Jisun%3BWhitten%2C+James+E&rft.aulast=Soares&rft.aufirst=Jason&rft.date=2010-02-01&rft.volume=7603&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Proceedings+of+SPIE+-+The+International+Society+for+Optical+Engineering&rft.issn=0277786X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-07-01 N1 - Last updated - 2011-11-14 ER - TY - JOUR T1 - Incidence of Ankle Sprains Among Active-Duty Members of the United States Armed Services From 1998 Through 2006 AN - 745901411; 12683188 AB - Context: Ankle sprains have been reported as one of the most common injuries sustained by members of the US Armed Services. However, little is known about the incidence rate and injury patterns associated with ankle sprains in this population. Objective: To examine the incidence of ankle sprains among active-duty members of the US Armed Services from 1998 through 2006. A secondary objective was to describe the sex, age, and service-specific injury patterns in this young, physically active population. Design: Cohort study. Patients or Other Participants: All active-duty service members from the day they enter military service until the day they leave military service and US Army Reserve and National Guard service members during periods of active duty and mobilization. Main Outcome Measure(s): Injury data were extracted from the Defense Medical Epidemiological Database from 1998 through 2006. All data for ankle sprains, coded according to the International Classification of Diseases (9th revision), were included. Cases were limited to those injuries reported as first occurrences. Incidence rates (IRs) were calculated per 1000 person-years by sex, age, and service. Incidence rate ratios (IRRs) and 95% confidence intervals (95% CIs) were used to assess the strength of association between the incidence of ankle sprain and the independent variables of sex, age, and service. Results: From 1998 through 2006, 423581 service members sustained ankle sprains and 12118863 person-years at risk to injury were documented in this population. The incidence rate was 34.95 (95% CI = 34.85, 35.06) per 1000 person-years at risk. Females were 21% more likely (IRR = 1.21, 95% CI = 1.21, 1.23) to sustain an ankle sprain than males. Sex-specific IR varied by age and service. Differences in the rate of ankle sprains were also noted by age and service. Conclusions: The incidence of ankle sprains among US service members was 5 times greater than that previously reported in civilian population studies. Sex, age, and branch of military service are important factors related to the incidence of ankle sprains in this population. JF - Journal of Athletic Training AU - Cameron, K L AU - Owens, B D AU - DeBerardino, T M AD - Orthopaedic Research, Keller Army Hospital, 900 Washington Road, West Point, NY 10996, USA, kenneth.cameron@amedd.army.mil Y1 - 2010/02// PY - 2010 DA - Feb 2010 SP - 29 EP - 38 VL - 45 IS - 1 SN - 1062-6050, 1062-6050 KW - Physical Education Index KW - Athletic training KW - Injuries KW - Classification KW - Ankles KW - Sprains KW - Diseases KW - Military KW - Youth KW - Sex KW - PE 090:Sports Medicine & Exercise Sport Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745901411?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Athletic+Training&rft.atitle=Incidence+of+Ankle+Sprains+Among+Active-Duty+Members+of+the+United+States+Armed+Services+From+1998+Through+2006&rft.au=Cameron%2C+K+L%3BOwens%2C+B+D%3BDeBerardino%2C+T+M&rft.aulast=Cameron&rft.aufirst=K&rft.date=2010-02-01&rft.volume=45&rft.issue=1&rft.spage=29&rft.isbn=&rft.btitle=&rft.title=Journal+of+Athletic+Training&rft.issn=10626050&rft_id=info:doi/ LA - English DB - Physical Education Index N1 - Date revised - 2010-05-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Athletic training; Classification; Injuries; Ankles; Diseases; Sprains; Military; Youth; Sex ER - TY - JOUR T1 - Phase II tungsten fate-and-transport study for Camp Edwards AN - 742911633; 2010-055650 JF - ERDC/CRREL Technical Report AU - Clausen, Jay L AU - Bednar, Anthony J AU - Lambert, Dennis J AU - Bailey, Ronald N AU - Kuhlbrush, Michael AU - Taylor, Susan AU - Bigl, Sue R Y1 - 2010/02// PY - 2010 DA - February 2010 SP - 126 PB - U. S. Army Corps of Engineers, Engineer Research and Development Center, Hanover, NH KW - United States KW - soils KW - hydrology KW - Cape Cod KW - pollutants KW - pollution KW - tungstates KW - ground water KW - attenuation KW - Barnstable County Massachusetts KW - tungsten KW - transport KW - Massachusetts KW - Camp Edwards KW - metals KW - natural attenuation KW - military facilities KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742911633?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/GeoRef&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=Clausen%2C+Jay+L%3BBednar%2C+Anthony+J%3BLambert%2C+Dennis+J%3BBailey%2C+Ronald+N%3BKuhlbrush%2C+Michael%3BTaylor%2C+Susan%3BBigl%2C+Sue+R&rft.aulast=Clausen&rft.aufirst=Jay&rft.date=2010-02-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=Phase+II+tungsten+fate-and-transport+study+for+Camp+Edwards&rft.title=Phase+II+tungsten+fate-and-transport+study+for+Camp+Edwards&rft.issn=&rft_id=info:doi/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2010-01-01 N1 - Number of references - 13 N1 - PubXState - NH N1 - Document feature - illus. incl. 14 tables, sketch maps N1 - SuppNotes - Includes 7 appendices N1 - Last updated - 2012-06-07 N1 - CODEN - #05435 N1 - SubjectsTermNotLitGenreText - attenuation; Barnstable County Massachusetts; Camp Edwards; Cape Cod; ground water; hydrology; Massachusetts; metals; military facilities; natural attenuation; pollutants; pollution; soils; transport; tungstates; tungsten; United States ER - TY - JOUR T1 - Epiglottitis due to nontypeable Haemophilus influenzae in a vaccinated child. AN - 742783599; pmid-20018387 AB - Once a prevalent disease, acute epiglottitis in children has become a rare entity. The introduction of the Haemophilus influenzae type b vaccine has had a dramatic impact on the number of invasive infections caused by this organism. However, physicians must be aware that epiglottitis may result from vaccine failures or from infection with other pathogenic organisms. Vaccinated children with epiglottitis present in a similar fashion to those who are not vaccinated. We present a rare case of acute epiglottitis in a fully vaccinated child due to nontypeable H. influenzae and discuss the clinical presentation and management. Published by Elsevier Ireland Ltd. JF - International journal of pediatric otorhinolaryngology AU - Rogers, Derek J AU - Sie, Kathleen C Y AU - Manning, Scott C AD - Madigan Army Medical Center, Otolaryngology-Head and Neck Surgery, Fitzsimmons Dr, Tacoma, WA 98431, United States. derek.john.rogers@amedd.army.mil Y1 - 2010/02// PY - 2010 DA - Feb 2010 SP - 218 EP - 220 VL - 74 IS - 2 SN - 0165-5876, 0165-5876 KW - Index Medicus KW - National Library of Medicine KW - Epiglottitis -- microbiology KW - Drug Therapy, Combination KW - Anti-Bacterial Agents -- therapeutic use KW - Humans KW - Epiglottitis -- radiography KW - Ampicillin -- therapeutic use KW - Tomography, X-Ray Computed KW - Sulbactam -- therapeutic use KW - Male KW - Vancomycin -- therapeutic use KW - Epiglottitis -- drug therapy KW - Child, Preschool KW - Haemophilus Infections -- complications KW - Haemophilus influenzae type b -- isolation & purification KW - Haemophilus Infections -- drug therapy KW - Haemophilus Infections -- prevention & control KW - Influenza Vaccines -- administration & dosage UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742783599?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+journal+of+pediatric+otorhinolaryngology&rft.atitle=Epiglottitis+due+to+nontypeable+Haemophilus+influenzae+in+a+vaccinated+child.&rft.au=Rogers%2C+Derek+J%3BSie%2C+Kathleen+C+Y%3BManning%2C+Scott+C&rft.aulast=Rogers&rft.aufirst=Derek&rft.date=2010-02-01&rft.volume=74&rft.issue=2&rft.spage=218&rft.isbn=&rft.btitle=&rft.title=International+journal+of+pediatric+otorhinolaryngology&rft.issn=01655876&rft_id=info:doi/ LA - English (eng) DB - ComDisDome N1 - Date revised - 2010-05-06 N1 - Last updated - 2010-09-25 ER - TY - JOUR T1 - Role of the otolaryngologist in the treatment of struma ovarii. AN - 742781471; pmid-20013844 AB - Struma ovarii, a rare germ cell tumor of the ovary composed of >50% thyroid tissue, is traditionally managed by gynecologic surgeons. Although struma ovarii is typically cured by simple excision, otolaryngology-head and neck surgeons may play a critical role in caring for these patients. In this article, we present two cases of struma ovarii and discuss the role of the otolaryngologist. JF - The Laryngoscope AU - Wirtz, Eric D AU - Bothwell, Nici AU - Klem, Christopher AD - Department of Otolaryngology, Tripler Army Medical Center, Tripler AMC, Honolulu, Hawaii 96859, USA. eric.d.wirtz@us.army.mil Y1 - 2010/02// PY - 2010 DA - Feb 2010 SP - 259 EP - 260 VL - 120 IS - 2 SN - 0023-852X, 0023-852X KW - Index Medicus KW - National Library of Medicine KW - Thyroid Neoplasms -- diagnosis KW - Humans KW - Adult KW - Middle Aged KW - Thyroid Neoplasms -- pathology KW - Thyroid Neoplasms -- surgery KW - Otolaryngology KW - Female KW - Ovarian Neoplasms -- secondary KW - Struma Ovarii -- surgery KW - Neoplasms, Multiple Primary -- diagnosis KW - Ovarian Neoplasms -- surgery KW - Struma Ovarii -- diagnosis KW - Ovarian Neoplasms -- diagnosis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742781471?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Laryngoscope&rft.atitle=Role+of+the+otolaryngologist+in+the+treatment+of+struma+ovarii.&rft.au=Wirtz%2C+Eric+D%3BBothwell%2C+Nici%3BKlem%2C+Christopher&rft.aulast=Wirtz&rft.aufirst=Eric&rft.date=2010-02-01&rft.volume=120&rft.issue=2&rft.spage=259&rft.isbn=&rft.btitle=&rft.title=The+Laryngoscope&rft.issn=0023852X&rft_id=info:doi/ LA - English (eng) DB - ComDisDome N1 - Date revised - 2010-04-13 N1 - Last updated - 2010-09-25 ER - TY - JOUR T1 - Alanine mutagenesis of the primary antigenic escape residue cluster, c1, of apical membrane antigen 1. AN - 734254198; 19948834 AB - Antibodies against apical membrane antigen 1 (AMA1) inhibit invasion of Plasmodium merozoites into red cells, and a large number of single nucleotide polymorphisms on AMA1 allow the parasite to escape inhibitory antibodies. The availability of a crystal structure makes it possible to test protein engineering strategies to develop a monovalent broadly reactive vaccine. Previously, we showed that a linear stretch of polymorphic residues (amino acids 187 to 207), localized within the C1 cluster on domain 1, conferred the highest level of escape from inhibitory antibodies, and these were termed antigenic escape residues (AER). Here we test the hypothesis that immunodampening the C1 AER will divert the immune system toward more conserved regions. We substituted seven C1 AER of the FVO strain Plasmodium falciparum AMA1 with alanine residues (ALA). The resulting ALA protein was less immunogenic than the native protein in rabbits. Anti-ALA antibodies contained a higher proportion of cross-reactive domain 2 and domain 3 antibodies and had higher avidity than anti-FVO. No overall enhancement of cross-reactive inhibitory activity was observed when anti-FVO and anti-ALA sera were compared for their ability to inhibit invasion. Alanine mutations at the C1 AER had shifted the immune response toward cross-strain-reactive epitopes that were noninhibitory, refuting the hypothesis but confirming the importance of the C1 cluster as an inhibitory epitope. We further demonstrate that naturally occurring polymorphisms that fall within the C1 cluster can predict escape from cross-strain invasion inhibition, reinforcing the importance of the C1 cluster genotype for antigenic categorization and allelic shift analyses in future phase 2b trials. JF - Infection and immunity AU - Dutta, Sheetij AU - Dlugosz, Lisa S AU - Clayton, Joshua W AU - Pool, Christopher D AU - Haynes, J David AU - Gasser, Robert A AU - Batchelor, Adrian H AD - Department of Epitope Mapping, Division of Malaria Vaccine Development, Walter Reed Army Institute of Research, 503 Robert Grant Ave., Silver Spring, MD 20910, USA. Sheetij.dutta@us.army.mil Y1 - 2010/02// PY - 2010 DA - February 2010 SP - 661 EP - 671 VL - 78 IS - 2 KW - Antibodies, Protozoan KW - 0 KW - Antigens, Protozoan KW - Malaria Vaccines KW - Membrane Proteins KW - Protozoan Proteins KW - apical membrane antigen I, Plasmodium KW - Alanine KW - OF5P57N2ZX KW - Index Medicus KW - Mutagenesis, Site-Directed KW - Polymerase Chain Reaction KW - Antibody Specificity KW - Animals KW - Blotting, Western KW - Antibodies, Protozoan -- immunology KW - Enzyme-Linked Immunosorbent Assay KW - Rabbits KW - Malaria Vaccines -- immunology KW - Cross Reactions KW - Protein Structure, Quaternary KW - Protozoan Proteins -- chemistry KW - Membrane Proteins -- chemistry KW - Membrane Proteins -- immunology KW - Antigens, Protozoan -- immunology KW - Antigens, Protozoan -- chemistry KW - Protozoan Proteins -- immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/734254198?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Infection+and+immunity&rft.atitle=Alanine+mutagenesis+of+the+primary+antigenic+escape+residue+cluster%2C+c1%2C+of+apical+membrane+antigen+1.&rft.au=Dutta%2C+Sheetij%3BDlugosz%2C+Lisa+S%3BClayton%2C+Joshua+W%3BPool%2C+Christopher+D%3BHaynes%2C+J+David%3BGasser%2C+Robert+A%3BBatchelor%2C+Adrian+H&rft.aulast=Dutta&rft.aufirst=Sheetij&rft.date=2010-02-01&rft.volume=78&rft.issue=2&rft.spage=661&rft.isbn=&rft.btitle=&rft.title=Infection+and+immunity&rft.issn=1098-5522&rft_id=info:doi/10.1128%2FIAI.00866-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-03-03 N1 - Date created - 2010-01-25 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Proc Natl Acad Sci U S A. 2008 Jun 3;105(22):7857-62 [18515425] PLoS One. 2008;3(1):e1465 [18213374] PLoS Pathog. 2009 Jan;5(1):e1000273 [19165323] PLoS One. 2009;4(4):e5254 [19390585] Vaccine. 2009 May 18;27(23):3090-8 [19428923] PLoS One. 2009;4(12):e8138 [19997632] Sci Transl Med. 2009 Oct 14;1(2):2ra5 [20165550] Mol Microbiol. 2000 Nov;38(4):706-18 [11115107] Infect Immun. 2001 May;69(5):3286-94 [11292751] Infect Immun. 2002 Jun;70(6):3101-10 [12011004] Methods Mol Med. 2002;72:535-54 [12125152] Infect Immun. 2002 Dec;70(12):6948-60 [12438374] Infect Immun. 2002 Dec;70(12):6961-7 [12438375] Genetics. 2003 Oct;165(2):555-61 [14573469] J Virol. 2004 Apr;78(8):4029-36 [15047819] Mol Microbiol. 2004 Apr;52(1):159-68 [15049818] Blood. 2004 Aug 1;104(3):704-10 [15073030] BMC Infect Dis. 2004 Sep 8;4:33 [15355548] Infect Immun. 1996 Mar;64(3):1054-9 [8641760] J Biol Chem. 1996 Nov 15;271(46):29446-52 [8910611] J Immunol. 1997 Jul 1;159(1):279-89 [9200464] J Infect Dis. 1999 Jan;179(1):31-6 [9841819] Infect Immun. 2005 Apr;73(4):2116-22 [15784553] Science. 2005 Apr 15;308(5720):408-11 [15731407] Proc Natl Acad Sci U S A. 2005 Sep 6;102(36):12736-41 [16129835] J Virol. 2005 Oct;79(19):12148-63 [16160142] Mol Biochem Parasitol. 2005 Nov;144(1):55-67 [16154214] Protein Sci. 2006 Nov;15(11):2558-67 [17001032] J Biol Chem. 2007 Mar 9;282(10):7431-41 [17192270] Vaccine. 2007 May 22;25(21):4203-12 [17442466] Proc Natl Acad Sci U S A. 2007 Jul 24;104(30):12488-93 [17636123] PLoS Pathog. 2007 Sep 7;3(9):1308-19 [17907804] Exp Parasitol. 2009 Feb;121(2):144-50 [19017530] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1128/IAI.00866-09 ER - TY - JOUR T1 - Characterization of a head-only aerosol exposure system for nonhuman primates. AN - 733932038; 20063997 AB - A well-characterized exposure chamber is necessary to generate reproducible atmospheres for inhalation toxicology studies. The aim of the present study was to characterize a head-only exposure chamber for non-human primates. Aerosols containing bovine serum albumin (BSA) were used to characterize a 16-L dynamic airflow head-only exposure chamber. A 250-ml plastic bottle with a respirator attached located inside the chamber was used to simulate a breathing head. Chamber leak rate, mixing, and aerosol spatial distributions were quantified. The chamber concentration profile was measured at the chamber exhaust using an aerodynamic particle sizer. Aerosol spatial distribution was determined by collecting filter samples at several chamber locations. The particle size distribution was determined by collecting cascade impactor samples at several chamber locations. The estimated chamber leak rate was within standards suggested in the literature. The measured average aerosol residence time was similar to theoretical aerosol residence time, suggesting that the chamber was mixing well. Additionally, the average concentration measured at each of the sampling locations within the chamber was similar, and the within-run coefficients of variation (CV) across all sampling locations was similar to those reported in previously published studies, again suggesting that the aerosol concentration throughout the chamber was uniform. The particle size distribution was similar throughout the exposure chamber. Additionally, the BSA concentration and particle size distributions measured in the breathing zone of the simulated head were not significantly different from measurements made elsewhere in the chamber, suggesting that respiration does not affect the average aerosol concentration or particle size distribution at the mouth. JF - Inhalation toxicology AU - Dabisch, P A AU - Kline, J AU - Lewis, C AU - Yeager, J AU - Pitt, M L M AD - Center for Aerobiological Sciences, United States Army Medical Research Institute of Infectious Disease, Fort Detrick, Maryland 21702, USA. paul.a.dabisch@us.army.mil Y1 - 2010/02// PY - 2010 DA - February 2010 SP - 224 EP - 233 VL - 22 IS - 3 KW - Aerosols KW - 0 KW - Serum Albumin, Bovine KW - Index Medicus KW - Animals KW - Serum Albumin, Bovine -- administration & dosage KW - Head KW - Particle Size KW - Linear Models KW - Reference Standards KW - Humidity KW - Air -- analysis KW - Equipment Design KW - Anesthesia KW - Tidal Volume -- physiology KW - Respiratory Mechanics -- physiology KW - Serum Albumin, Bovine -- chemistry KW - Air Pressure KW - Primates -- physiology KW - Inhalation Exposure KW - Atmosphere Exposure Chambers UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733932038?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Inhalation+toxicology&rft.atitle=Characterization+of+a+head-only+aerosol+exposure+system+for+nonhuman+primates.&rft.au=Dabisch%2C+P+A%3BKline%2C+J%3BLewis%2C+C%3BYeager%2C+J%3BPitt%2C+M+L+M&rft.aulast=Dabisch&rft.aufirst=P&rft.date=2010-02-01&rft.volume=22&rft.issue=3&rft.spage=224&rft.isbn=&rft.btitle=&rft.title=Inhalation+toxicology&rft.issn=1091-7691&rft_id=info:doi/10.3109%2F08958370903191023 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-04-30 N1 - Date created - 2010-02-12 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.3109/08958370903191023 ER - TY - JOUR T1 - Adsorption/desorption measurements of nitroglycerin and dinitrotoluene in Camp Edwards, Massachusetts soil AN - 50058930; 2010-033112 JF - ERDC/CRREL Technical Report AU - Clausen, Jay L AU - Scott, Connie L AU - Mulherin, Nathan D AU - Bigl, Susan R AU - Gooch, Gordan E AU - Douglas, Thomas A AU - Osgerby, I AU - Palm, B Y1 - 2010/02// PY - 2010 DA - February 2010 SP - 164 PB - U. S. Army Corps of Engineers, Engineer Research and Development Center, Hanover, NH KW - United States KW - soils KW - desorption KW - pollutants KW - pollution KW - adsorption KW - environmental analysis KW - environmental management KW - organic compounds KW - mitigation KW - Barnstable County Massachusetts KW - nitroglycerin KW - explosives KW - transport KW - Massachusetts KW - Camp Edwards KW - military facilities KW - dinitrotoluene KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50058930?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/GeoRef&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=Clausen%2C+Jay+L%3BScott%2C+Connie+L%3BMulherin%2C+Nathan+D%3BBigl%2C+Susan+R%3BGooch%2C+Gordan+E%3BDouglas%2C+Thomas+A%3BOsgerby%2C+I%3BPalm%2C+B&rft.aulast=Clausen&rft.aufirst=Jay&rft.date=2010-02-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=Adsorption%2Fdesorption+measurements+of+nitroglycerin+and+dinitrotoluene+in+Camp+Edwards%2C+Massachusetts+soil&rft.title=Adsorption%2Fdesorption+measurements+of+nitroglycerin+and+dinitrotoluene+in+Camp+Edwards%2C+Massachusetts+soil&rft.issn=&rft_id=info:doi/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2014, American Geosciences Institute. N1 - Date revised - 2010-01-01 N1 - Number of references - 65 N1 - PubXState - NH N1 - Document feature - illus. incl. 31 tables, sketch maps N1 - SuppNotes - Includes 10 appendices, final report N1 - Last updated - 2014-09-18 N1 - CODEN - #05435 N1 - SubjectsTermNotLitGenreText - adsorption; Barnstable County Massachusetts; Camp Edwards; desorption; dinitrotoluene; environmental analysis; environmental management; explosives; Massachusetts; military facilities; mitigation; nitroglycerin; organic compounds; pollutants; pollution; soils; transport; United States ER - TY - JOUR T1 - Dissolution rate, weathering mechanics, and friability of TNT, Comp B, Tritonal, and Octol AN - 50058901; 2010-033160 JF - ERDC/CRREL Technical Report AU - Taylor, Susan AU - Lever, James H AU - Walsh, Marianne E AU - Fadden, Jennifer AU - Perron, Nancy M AU - Bigl, Susan R AU - Spanggord, Ronald AU - Curnow, Matthew AU - Packer, Bonnie Y1 - 2010/02// PY - 2010 DA - February 2010 SP - 164 PB - U. S. Army Corps of Engineers, Engineer Research and Development Center, Hanover, NH KW - soils KW - Octol KW - pollutants KW - pollution KW - trinitrotoluene KW - Comp B KW - solution KW - weathering KW - models KW - organic compounds KW - mitigation KW - Tritonal KW - military geology KW - explosives KW - chemical reactions KW - conservation KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50058901?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/GeoRef&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=Taylor%2C+Susan%3BLever%2C+James+H%3BWalsh%2C+Marianne+E%3BFadden%2C+Jennifer%3BPerron%2C+Nancy+M%3BBigl%2C+Susan+R%3BSpanggord%2C+Ronald%3BCurnow%2C+Matthew%3BPacker%2C+Bonnie&rft.aulast=Taylor&rft.aufirst=Susan&rft.date=2010-02-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Photochemistry+and+Photobiology&rft.issn=00318655&rft_id=info:doi/10.1111%2Fj.1751-1097.2008.00387.x LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2014, American Geosciences Institute. N1 - Date revised - 2010-01-01 N1 - Number of references - 52 N1 - PubXState - NH N1 - Document feature - illus. incl. 17 tables N1 - SuppNotes - Final report, includes 2 appendices N1 - Last updated - 2014-09-18 N1 - CODEN - #05435 N1 - SubjectsTermNotLitGenreText - chemical reactions; Comp B; conservation; explosives; military geology; mitigation; models; Octol; organic compounds; pollutants; pollution; soils; solution; trinitrotoluene; Tritonal; weathering ER - TY - JOUR T1 - Normal and sliding contact experiments on gneiss AN - 50054843; 2010-031097 JF - Granular Matter AU - Cole, David M AU - Mathisen, Lillian Uthus AU - Hopkins, Mark A AU - Knapp, Byron R Y1 - 2010/02// PY - 2010 DA - February 2010 SP - 69 EP - 86 PB - Springer, Berlin; Heidelberg VL - 12 IS - 1 SN - 1434-5021, 1434-5021 KW - gneisses KW - discrete element analysis KW - experimental studies KW - metamorphic rocks KW - stiffness KW - mechanical properties KW - triaxial tests KW - rock mechanics KW - 30:Engineering geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50054843?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Granular+Matter&rft.atitle=Normal+and+sliding+contact+experiments+on+gneiss&rft.au=Cole%2C+David+M%3BMathisen%2C+Lillian+Uthus%3BHopkins%2C+Mark+A%3BKnapp%2C+Byron+R&rft.aulast=Cole&rft.aufirst=David&rft.date=2010-02-01&rft.volume=12&rft.issue=1&rft.spage=69&rft.isbn=&rft.btitle=&rft.title=Granular+Matter&rft.issn=14345021&rft_id=info:doi/10.1007%2Fs10035-010-0165-z L2 - http://www.springerlink.com/content/102500/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2010-01-01 N1 - Number of references - 19 N1 - Document feature - illus. incl. 3 tables N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - discrete element analysis; experimental studies; gneisses; mechanical properties; metamorphic rocks; rock mechanics; stiffness; triaxial tests DO - http://dx.doi.org/10.1007/s10035-010-0165-z ER - TY - CPAPER T1 - Radar profiles of stratigraphic structures in the Antarctic ice sheets T2 - International Glaciological Conference Ice and Climate Change: A View from the South (VICC 2010) AN - 42340360; 5656310 JF - International Glaciological Conference Ice and Climate Change: A View from the South (VICC 2010) AU - Arcone, Steven Y1 - 2010/02/01/ PY - 2010 DA - 2010 Feb 01 KW - Radar KW - Ice KW - Stratigraphy KW - Glaciation KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42340360?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=International+Glaciological+Conference+Ice+and+Climate+Change%3A+A+View+from+the+South+%28VICC+2010%29&rft.atitle=Radar+profiles+of+stratigraphic+structures+in+the+Antarctic+ice+sheets&rft.au=Arcone%2C+Steven&rft.aulast=Arcone&rft.aufirst=Steven&rft.date=2010-02-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=International+Glaciological+Conference+Ice+and+Climate+Change%3A+A+View+from+the+South+%28VICC+2010%29&rft.issn=&rft_id=info:doi/ L2 - http://www.cecs.cl/VICC2010/abstractbook.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Radio Frequency Identification AN - 21505193; 12492975 AB - Someone once said "You're never more than 10 feet from an arachnid." Today, the expression might be, "You're never more than 10 feet from an RFID." The acronym stands for Radio Frequency Identification, and is used to describe a plethora of applications from loss prevention and unlocking office doors using low-end technology to locating high-cost equipment to providing container inventories at transfer points and destinations using high-end technology. JF - Biomedical Instrumentation & Technology AU - Dondelinger, R M AD - U.S. Military Entrance Processing Command in North Chicago, IL, USA, robert.dondelinger@mepcom.army.mil Y1 - 2010/02// PY - 2010 DA - Feb 2010 SP - 44 EP - 47 PB - Association for the Advancement of Medical Instrumentation VL - 44 IS - 1 SN - 0899-8205, 0899-8205 KW - Biotechnology and Bioengineering Abstracts KW - Inventories KW - W 30965:Miscellaneous, Reviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21505193?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biomedical+Instrumentation+%26+Technology&rft.atitle=Radio+Frequency+Identification&rft.au=Dondelinger%2C+R+M&rft.aulast=Dondelinger&rft.aufirst=R&rft.date=2010-02-01&rft.volume=44&rft.issue=1&rft.spage=44&rft.isbn=&rft.btitle=&rft.title=Biomedical+Instrumentation+%26+Technology&rft.issn=08998205&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Inventories ER - TY - JOUR T1 - The Long History of Gaming in Military Training AN - 1567043920; 201435634 AB - The dual-use of games in both military and entertainment applications has a long history. This has taken the form of sand tables, miniatures, board games, and computer games. The current tension between entertainment and military applications over games is just the return of similar concerns that have surrounded gaming tools and technologies in previous generations. Dynamic representations of the physical world are interesting and useful tools in a number of fields, to include the military, city planning, architecture, education, and entertainment. Modern computer games contain technologies and tools that allow many different communities to accomplish similar goals. [Reprinted by permission of Sage Publications Inc., copyright holder.] JF - Simulation & Gaming AU - Smith, Roger AD - U.S. Army PEO for Simulation, Training, and Instrumentation, USA roger.smith14@us.army.mil Y1 - 2010/02// PY - 2010 DA - February 2010 SP - 6 EP - 19 PB - Sage Publications, Thousand Oaks CA VL - 41 IS - 1 SN - 1046-8781, 1046-8781 KW - 3D engine artificial intelligence behavior scripting tools board game computer game economics 3D engine entertainment game technologies graphical user interface history mathematical models miniatures networking persistent worlds physical models sand table serious games simulation strategy board games training visualization wargame world building tools KW - Physical Education KW - Training KW - City Planning KW - Architecture KW - Armed Forces KW - article KW - 0623: complex organization; military sociology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1567043920?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocabs&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Simulation+%26+Gaming&rft.atitle=The+Long+History+of+Gaming+in+Military+Training&rft.au=Smith%2C+Roger&rft.aulast=Smith&rft.aufirst=Roger&rft.date=2010-02-01&rft.volume=41&rft.issue=1&rft.spage=6&rft.isbn=&rft.btitle=&rft.title=Simulation+%26+Gaming&rft.issn=00264148&rft_id=info:doi/ LA - English DB - Sociological Abstracts N1 - Date revised - 2014-10-01 N1 - Last updated - 2016-09-28 N1 - CODEN - SIGAEI N1 - SubjectsTermNotLitGenreText - Armed Forces; City Planning; Architecture; Training; Physical Education DO - http://dx.doi.org/10.1177/1046878109334330 ER - TY - CPAPER T1 - Update on the type II strained layer superlattice progress and discussion of its development strategy T2 - 2010 SPIE Photonics West AN - 754170784; 5718998 JF - 2010 SPIE Photonics West AU - Tidrow, Meimei Y1 - 2010/01/23/ PY - 2010 DA - 2010 Jan 23 KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754170784?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2010+SPIE+Photonics+West&rft.atitle=Update+on+the+type+II+strained+layer+superlattice+progress+and+discussion+of+its+development+strategy&rft.au=Tidrow%2C+Meimei&rft.aulast=Tidrow&rft.aufirst=Meimei&rft.date=2010-01-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2010+SPIE+Photonics+West&rft.issn=&rft_id=info:doi/ L2 - http://spie.org/Documents/ConferencesExhibitions/PW2010-Advance-Progra LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - Performance analysis of InAs/Ga(In)Sb strained layer superlattice detectors and focal plane arrays T2 - 2010 SPIE Photonics West AN - 754169678; 5718999 JF - 2010 SPIE Photonics West AU - Bandara, Sumith Y1 - 2010/01/23/ PY - 2010 DA - 2010 Jan 23 KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754169678?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2010+SPIE+Photonics+West&rft.atitle=Performance+analysis+of+InAs%2FGa%28In%29Sb+strained+layer+superlattice+detectors+and+focal+plane+arrays&rft.au=Bandara%2C+Sumith&rft.aulast=Bandara&rft.aufirst=Sumith&rft.date=2010-01-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2010+SPIE+Photonics+West&rft.issn=&rft_id=info:doi/ L2 - http://spie.org/Documents/ConferencesExhibitions/PW2010-Advance-Progra LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - Electro-optic co-site interference mitigation T2 - 2010 SPIE Photonics West AN - 754165354; 5718941 JF - 2010 SPIE Photonics West AU - Bruno, Jonathan Y1 - 2010/01/23/ PY - 2010 DA - 2010 Jan 23 KW - Mitigation KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754165354?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2010+SPIE+Photonics+West&rft.atitle=Electro-optic+co-site+interference+mitigation&rft.au=Bruno%2C+Jonathan&rft.aulast=Bruno&rft.aufirst=Jonathan&rft.date=2010-01-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2010+SPIE+Photonics+West&rft.issn=&rft_id=info:doi/ L2 - http://spie.org/Documents/ConferencesExhibitions/PW2010-Advance-Progra LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - Applications of zinc oxide to UV photonics T2 - 2010 SPIE Photonics West AN - 754163317; 5718740 JF - 2010 SPIE Photonics West AU - Gerhold, Michael Y1 - 2010/01/23/ PY - 2010 DA - 2010 Jan 23 KW - Zinc oxide KW - U.V. radiation KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754163317?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2010+SPIE+Photonics+West&rft.atitle=Applications+of+zinc+oxide+to+UV+photonics&rft.au=Gerhold%2C+Michael&rft.aulast=Gerhold&rft.aufirst=Michael&rft.date=2010-01-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2010+SPIE+Photonics+West&rft.issn=&rft_id=info:doi/ L2 - http://spie.org/Documents/ConferencesExhibitions/PW2010-Advance-Progra LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - Detector development for X-ray imaging T2 - 2010 SPIE Photonics West AN - 754163012; 5718439 JF - 2010 SPIE Photonics West AU - Mentzer, Mark AU - Herr, Doug Y1 - 2010/01/23/ PY - 2010 DA - 2010 Jan 23 KW - Ionizing radiation KW - Imaging techniques KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754163012?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2010+SPIE+Photonics+West&rft.atitle=Detector+development+for+X-ray+imaging&rft.au=Mentzer%2C+Mark%3BHerr%2C+Doug&rft.aulast=Mentzer&rft.aufirst=Mark&rft.date=2010-01-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2010+SPIE+Photonics+West&rft.issn=&rft_id=info:doi/ L2 - http://spie.org/Documents/ConferencesExhibitions/PW2010-Advance-Progra LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - Effect of surface modification on the optical properties nanocrystalline zinc oxide materials T2 - 2010 SPIE Photonics West AN - 754159195; 5718752 JF - 2010 SPIE Photonics West AU - Steeves, Diane AU - Singh, Jagdeep AU - Im, Jisun AU - Whitten, James AU - Soares, Jason Y1 - 2010/01/23/ PY - 2010 DA - 2010 Jan 23 KW - Zinc oxide KW - Optical properties KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754159195?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2010+SPIE+Photonics+West&rft.atitle=Effect+of+surface+modification+on+the+optical+properties+nanocrystalline+zinc+oxide+materials&rft.au=Steeves%2C+Diane%3BSingh%2C+Jagdeep%3BIm%2C+Jisun%3BWhitten%2C+James%3BSoares%2C+Jason&rft.aulast=Steeves&rft.aufirst=Diane&rft.date=2010-01-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2010+SPIE+Photonics+West&rft.issn=&rft_id=info:doi/ L2 - http://spie.org/Documents/ConferencesExhibitions/PW2010-Advance-Progra LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - Application of novel hyperspectral imaging technologies in combat casualty care T2 - 2010 SPIE Photonics West AN - 754156556; 5718285 JF - 2010 SPIE Photonics West AU - Cancio, Leopoldo Y1 - 2010/01/23/ PY - 2010 DA - 2010 Jan 23 KW - Technology KW - Imaging techniques KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754156556?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2010+SPIE+Photonics+West&rft.atitle=Application+of+novel+hyperspectral+imaging+technologies+in+combat+casualty+care&rft.au=Cancio%2C+Leopoldo&rft.aulast=Cancio&rft.aufirst=Leopoldo&rft.date=2010-01-23&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2010+SPIE+Photonics+West&rft.issn=&rft_id=info:doi/ L2 - http://spie.org/Documents/ConferencesExhibitions/PW2010-Advance-Progra LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-02 N1 - Last updated - 2010-09-25 ER - TY - CPAPER T1 - Urban turbulence spectra from field observations T2 - 90th Annual Meeting of the American Meteorological Society AN - 742803525; 5677299 JF - 90th Annual Meeting of the American Meteorological Society AU - Chang, Sam AU - Huynh, G AU - Tofsted, D AU - Garvey, D AU - Williamson, C AU - Li, D. Y1 - 2010/01/17/ PY - 2010 DA - 2010 Jan 17 KW - Turbulence KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742803525?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=90th+Annual+Meeting+of+the+American+Meteorological+Society&rft.atitle=Urban+turbulence+spectra+from+field+observations&rft.au=Chang%2C+Sam%3BHuynh%2C+G%3BTofsted%2C+D%3BGarvey%2C+D%3BWilliamson%2C+C%3BLi%2C+D.&rft.aulast=Chang&rft.aufirst=Sam&rft.date=2010-01-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=90th+Annual+Meeting+of+the+American+Meteorological+Society&rft.issn=&rft_id=info:doi/ L2 - http://ams.confex.com/ams/90annual/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-17 N1 - Last updated - 2010-08-14 ER - TY - CPAPER T1 - Turbulence anisotropy in an urban canyon and intersections T2 - 90th Annual Meeting of the American Meteorological Society AN - 742803449; 5677288 JF - 90th Annual Meeting of the American Meteorological Society AU - Klipp, Cheryl Y1 - 2010/01/17/ PY - 2010 DA - 2010 Jan 17 KW - Canyons KW - Turbulence KW - Anisotropy KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742803449?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=90th+Annual+Meeting+of+the+American+Meteorological+Society&rft.atitle=Turbulence+anisotropy+in+an+urban+canyon+and+intersections&rft.au=Klipp%2C+Cheryl&rft.aulast=Klipp&rft.aufirst=Cheryl&rft.date=2010-01-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=90th+Annual+Meeting+of+the+American+Meteorological+Society&rft.issn=&rft_id=info:doi/ L2 - http://ams.confex.com/ams/90annual/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-17 N1 - Last updated - 2010-08-14 ER - TY - CPAPER T1 - The Enhancement of the Dugway Proving Ground Meteorological Sensing Capabilities T2 - 90th Annual Meeting of the American Meteorological Society AN - 742795963; 5677444 JF - 90th Annual Meeting of the American Meteorological Society AU - Gallagher, Frank AU - Storwold, D Y1 - 2010/01/17/ PY - 2010 DA - 2010 Jan 17 KW - Meteorology KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742795963?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=90th+Annual+Meeting+of+the+American+Meteorological+Society&rft.atitle=The+Enhancement+of+the+Dugway+Proving+Ground+Meteorological+Sensing+Capabilities&rft.au=Gallagher%2C+Frank%3BStorwold%2C+D&rft.aulast=Gallagher&rft.aufirst=Frank&rft.date=2010-01-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=90th+Annual+Meeting+of+the+American+Meteorological+Society&rft.issn=&rft_id=info:doi/ L2 - http://ams.confex.com/ams/90annual/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-17 N1 - Last updated - 2010-08-14 ER - TY - CPAPER T1 - An evaluation of several wet bulb globe temperature algorithms at Dugway Proving Ground T2 - 90th Annual Meeting of the American Meteorological Society AN - 742792743; 5677432 JF - 90th Annual Meeting of the American Meteorological Society AU - Gallagher, Frank AU - Curtis, M Y1 - 2010/01/17/ PY - 2010 DA - 2010 Jan 17 KW - Temperature effects KW - Algorithms KW - Bulbs KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742792743?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=90th+Annual+Meeting+of+the+American+Meteorological+Society&rft.atitle=An+evaluation+of+several+wet+bulb+globe+temperature+algorithms+at+Dugway+Proving+Ground&rft.au=Gallagher%2C+Frank%3BCurtis%2C+M&rft.aulast=Gallagher&rft.aufirst=Frank&rft.date=2010-01-17&rft.volume=13&rft.issue=3&rft.spage=v&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+%26+Engineering+Geophysics&rft.issn=10831363&rft_id=info:doi/10.2113%2FJEEG13.3.fmv L2 - http://ams.confex.com/ams/90annual/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-17 N1 - Last updated - 2010-08-14 ER - TY - CPAPER T1 - Eddy covariance measurements of turbulence in and above a roughness sublayer T2 - 90th Annual Meeting of the American Meteorological Society AN - 742792425; 5677301 JF - 90th Annual Meeting of the American Meteorological Society AU - Garvey, Dennis AU - Chang, S AU - Williamson, C AU - Huynh, G AU - Li, D. Y1 - 2010/01/17/ PY - 2010 DA - 2010 Jan 17 KW - Turbulence KW - Oceanic eddies KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742792425?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=90th+Annual+Meeting+of+the+American+Meteorological+Society&rft.atitle=Eddy+covariance+measurements+of+turbulence+in+and+above+a+roughness+sublayer&rft.au=Garvey%2C+Dennis%3BChang%2C+S%3BWilliamson%2C+C%3BHuynh%2C+G%3BLi%2C+D.&rft.aulast=Garvey&rft.aufirst=Dennis&rft.date=2010-01-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=90th+Annual+Meeting+of+the+American+Meteorological+Society&rft.issn=&rft_id=info:doi/ L2 - http://ams.confex.com/ams/90annual/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-17 N1 - Last updated - 2010-08-14 ER - TY - CPAPER T1 - The NCAR-ATEC 4D Weather (4DWX) Modeling System: Updates and New Developments T2 - 90th Annual Meeting of the American Meteorological Society AN - 742791602; 5677515 JF - 90th Annual Meeting of the American Meteorological Society AU - Pace, John AU - Halvorson, S AU - Krippner, S AU - Gallagher III, F AU - Reynolds, J AU - Liu, Y AU - Warner, T AU - Swerdlin, S AU - Chen, F AU - Knievel, J AU - Hacker, J Y1 - 2010/01/17/ PY - 2010 DA - 2010 Jan 17 KW - Weather KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742791602?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=90th+Annual+Meeting+of+the+American+Meteorological+Society&rft.atitle=The+NCAR-ATEC+4D+Weather+%284DWX%29+Modeling+System%3A+Updates+and+New+Developments&rft.au=Pace%2C+John%3BHalvorson%2C+S%3BKrippner%2C+S%3BGallagher+III%2C+F%3BReynolds%2C+J%3BLiu%2C+Y%3BWarner%2C+T%3BSwerdlin%2C+S%3BChen%2C+F%3BKnievel%2C+J%3BHacker%2C+J&rft.aulast=Pace&rft.aufirst=John&rft.date=2010-01-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=90th+Annual+Meeting+of+the+American+Meteorological+Society&rft.issn=&rft_id=info:doi/ L2 - http://ams.confex.com/ams/90annual/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-17 N1 - Last updated - 2010-08-14 ER - TY - CPAPER T1 - Nocturnal low-level-jet generated gravity waves and turbulence over Oklahoma City during inversion breakup T2 - 90th Annual Meeting of the American Meteorological Society AN - 742790752; 5677300 JF - 90th Annual Meeting of the American Meteorological Society AU - Wang, Yansen AU - Garvey, D Y1 - 2010/01/17/ PY - 2010 DA - 2010 Jan 17 KW - USA, Oklahoma, Oklahoma City KW - Urban areas KW - Inversion KW - Turbulence KW - Gravity waves KW - Waves KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742790752?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=90th+Annual+Meeting+of+the+American+Meteorological+Society&rft.atitle=Nocturnal+low-level-jet+generated+gravity+waves+and+turbulence+over+Oklahoma+City+during+inversion+breakup&rft.au=Wang%2C+Yansen%3BGarvey%2C+D&rft.aulast=Wang&rft.aufirst=Yansen&rft.date=2010-01-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=90th+Annual+Meeting+of+the+American+Meteorological+Society&rft.issn=&rft_id=info:doi/ L2 - http://ams.confex.com/ams/90annual/techprogram/MEETING.HTM LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-17 N1 - Last updated - 2010-08-14 ER - TY - CPAPER T1 - Intelligent ground vehicle competition T2 - Intelligent Robots and Computer Vision XXVII: Algorithms and Techniques AN - 42307516; 5640850 JF - Intelligent Robots and Computer Vision XXVII: Algorithms and Techniques AU - Theisen, Bernard Y1 - 2010/01/17/ PY - 2010 DA - 2010 Jan 17 KW - Competition KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42307516?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Intelligent+Robots+and+Computer+Vision+XXVII%3A+Algorithms+and+Techniques&rft.atitle=Intelligent+ground+vehicle+competition&rft.au=Theisen%2C+Bernard&rft.aulast=Theisen&rft.aufirst=Bernard&rft.date=2010-01-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Intelligent+Robots+and+Computer+Vision+XXVII%3A+Algorithms+and+Techniques&rft.issn=&rft_id=info:doi/ L2 - http://spie.org/Documents/ConferencesExhibitions/ei10-Advance-L.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CONF T1 - 144 Turbulence anisotropy in an urban canyon and intersections AN - 918072087; 16192022 AB - Turbulence near a solid surface is not isotropic. As a consequence, dispersion is greater in some directions than in others at any location in an urban boundary layer. A better characterization of the anisotropy should lead to better modeling of turbulent dispersion. Using data from JU2003, the degree of anisotropy as well as the largest and smallest dispersion directions will be shown for various locations in the Park Avenue canyon as well as at the intersections at either end of the canyon. Values for an open area will also be shown for comparison. JF - American Meteorological Society. [np]. 16 Jan 2010. AU - Klipp, Cheryl L Y1 - 2010/01/16/ PY - 2010 DA - 2010 Jan 16 PB - American Meteorological Society KW - ASFA 2: Ocean Technology Policy & Non-Living Resources; Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Pollution monitoring KW - Atmospheric pollution models KW - Atmospheric pollution measurements KW - Pollution dispersion KW - Turbulence measurement KW - Atmospheric pollution dispersion KW - Meteorology KW - Dispersion in boundary layer KW - American Meteorological Society KW - Turbulence KW - Anisotropy KW - Conferences KW - Turbulence measurements KW - canyons KW - Air pollution KW - Boundary layers KW - Urban atmospheric pollution KW - Dispersion models KW - turbulence measurement KW - Dispersion KW - Q2 09263:Topography and morphology KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/918072087?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=144+Turbulence+anisotropy+in+an+urban+canyon+and+intersections&rft.au=Klipp%2C+Cheryl+L&rft.aulast=Klipp&rft.aufirst=Cheryl&rft.date=2010-01-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-01-01 N1 - Last updated - 2014-05-02 ER - TY - CONF T1 - Urban turbulence spectra from field observations AN - 918056756; 16191941 AB - Abstract A simple analytical form is used to model turbulent velocity and temperature spectra obtained from measurements with sonic anemometers mounted on a tall tower in an urban boundary layer. The form of the function used to model the spectra has two free parameters determined from the measurements with a non-linear curve fitting method. Conducted in Oklahoma City in the summer of 2003, the Joint Urban 2003 (JU2003) field experiments were a cooperative undertaking to study transport and dispersion in the turbulent atmospheric boundary layer. Sonic anemometer data taken using Lawrence Livermore National Laboratory's 83-m pseudo tower from JU2003 are analyzed. We present the results of characteristics of the urban turbulence spectra. In particular, we investigate the vertical variations detected in the urban spectra. We also discuss differences in the spectra observed over urban and non-urban areas. JF - American Meteorological Society. [np]. 16 Jan 2010. AU - Chang, Sam AU - Huynh, G D AU - Tofsted, D H AU - Garvey, D M AU - Williamson, C C AU - Li, D K Y1 - 2010/01/16/ PY - 2010 DA - 2010 Jan 16 PB - American Meteorological Society KW - ASFA 2: Ocean Technology Policy & Non-Living Resources; Pollution Abstracts; Meteorological & Geoastrophysical Abstracts KW - Pollution monitoring KW - Atmospheric pollution models KW - Atmospheric pollution measurements KW - Pollution dispersion KW - Measuring instruments KW - USA, Oklahoma, Oklahoma City KW - Turbulence measurement KW - Anemometers KW - Meteorology KW - Dispersion in boundary layer KW - Sonic anemometers KW - American Meteorological Society KW - Atmospheric boundary layer KW - cooperatives KW - Turbulence KW - Turbulent boundary layer KW - Urban areas KW - Conferences KW - Turbulence measurements KW - Air pollution KW - Boundary layers KW - Urban atmospheric pollution KW - Turbulence spectra KW - Dispersion KW - Q2 09243:Structure, mechanics and thermodynamics KW - M2 551.510.42:Air Pollution (551.510.42) KW - P 0000:AIR POLLUTION UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/918056756?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=&rft.atitle=Urban+turbulence+spectra+from+field+observations&rft.au=Chang%2C+Sam%3BHuynh%2C+G+D%3BTofsted%2C+D+H%3BGarvey%2C+D+M%3BWilliamson%2C+C+C%3BLi%2C+D+K&rft.aulast=Chang&rft.aufirst=Sam&rft.date=2010-01-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-01-01 N1 - Last updated - 2014-05-02 ER - TY - JOUR T1 - Results of the first phase 1 clinical trial of the HER-2/neu peptide (GP2) vaccine in disease-free breast cancer patients AN - 746051916; 12746220 AB - BACKGROUND: HER-2/neu, overexpressed in breast cancer, is a source of immunogenic peptides that include GP2 and E75. Phase 2 testing of E75 as an adjuvant vaccine has suggested a clinical benefit. GP2, derived from the transmembrane portion of HER-2/neu, has differing binding characteristics and may be more immunogenic than E75. Results of the first phase 1 trial of GP2 peptide vaccine are presented. METHODS: Disease-free, lymph node-negative, human leukocyte antigen (HLA)-A2+ breast cancer patients were enrolled. This dose escalation trial included 4 groups to determine safety and optimal GP2 peptide/granulocyte-macrophage colony-stimulating factor (GM-CSF) dose. Toxicities were monitored. Immunologic response was assessed ex vivo via the HLA-A2:immunoglobulin dimer assay to detect GP2-specific CD8+ T cells (and E75-specific CD8+ T cells to assess epitope spreading) and in vivo via delayed type hypersensitivity (DTH) reaction (medians/ranges). RESULTS: Eighteen patients were enrolled. All toxicities were grade 2. Eight (88.9%) of 9 patients in the first 3 dose groups required GM-CSF dose reductions for local reactions 100 mm or grade 2 systemic toxicity. GM-CSF dose was reduced to 125 g for the final dose group. All patients responded immunologically ex vivo (GP2-specific CD8+ T cells from prevaccination to maximum, 0.4% [0.0%-2.0%] to 1.1% [0.4%-3.6%], P < .001) and in vivo (GP2 pre- to postvaccination DTH, 0 mm [0.0-19.5 mm] to 27.5 mm [0.0-114.5 mm, P < .001). E75-specific CD8+ T cells also increased in response to GP2 from prevaccination to maximum (0.8% [0.0%-2.41%] to 1.6% [0.86%-3.72%], P < .001). CONCLUSIONS: The GP2 peptide vaccine appears safe and well tolerated with minimal local/systemic toxicity. GP2 elicited HER-2/neu-specific immune responses, including epitope spreading, in high-risk, lymph node-negative breast cancer patients. These findings support further investigation of the GP2 vaccine for the prevention of breast cancer recurrence. Cancer 2010. JF - Cancer AU - Carmichael, Mark G AU - Benavides, Linda C AU - Holmes, Jarrod P AU - Gates, Jeremy D AU - Mittendorf, Elizabeth A AU - Ponniah, Sathibalan AU - Peoples, George E AD - Cancer Vaccine Development Program, United States Military Cancer Institute, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, Maryland, George.Peoples@amedd.army.mil Y1 - 2010/01/15/ PY - 2010 DA - 2010 Jan 15 SP - 292 EP - 301 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 USA VL - 116 IS - 2 SN - 0008-543X, 0008-543X KW - Risk Abstracts; Immunology Abstracts KW - Histocompatibility antigen HLA KW - vaccines KW - ErbB-2 protein KW - Granulocyte-macrophage colony-stimulating factor KW - Lymph KW - Adjuvants KW - CD8 antigen KW - Toxicity KW - clinical trials KW - Clinical trials KW - Cancer KW - hypersensitivity KW - Hypersensitivity (delayed) KW - Immunogenicity KW - prevention KW - Lymphocytes T KW - Breast cancer KW - Risk groups KW - Vaccines KW - Epitopes KW - F 06925:Hypersensitivity KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/746051916?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cancer&rft.atitle=Results+of+the+first+phase+1+clinical+trial+of+the+HER-2%2Fneu+peptide+%28GP2%29+vaccine+in+disease-free+breast+cancer+patients&rft.au=Carmichael%2C+Mark+G%3BBenavides%2C+Linda+C%3BHolmes%2C+Jarrod+P%3BGates%2C+Jeremy+D%3BMittendorf%2C+Elizabeth+A%3BPonniah%2C+Sathibalan%3BPeoples%2C+George+E&rft.aulast=Carmichael&rft.aufirst=Mark&rft.date=2010-01-15&rft.volume=116&rft.issue=2&rft.spage=292&rft.isbn=&rft.btitle=&rft.title=Cancer&rft.issn=0008543X&rft_id=info:doi/10.1002%2Fcncr.24756 L2 - http://www3.interscience.wiley.com/journal/122687710/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-05-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Histocompatibility antigen HLA; ErbB-2 protein; Granulocyte-macrophage colony-stimulating factor; Lymph; Toxicity; CD8 antigen; Adjuvants; Clinical trials; Hypersensitivity (delayed); Immunogenicity; Lymphocytes T; Risk groups; Breast cancer; Vaccines; Epitopes; hypersensitivity; vaccines; prevention; clinical trials; Cancer DO - http://dx.doi.org/10.1002/cncr.24756 ER - TY - JOUR T1 - Energetic residues from field disposal of gun propellants AN - 744611977; 13010098 AB - Military training with howitzers and mortars produces excess propellant that is burned on the training range and can result in point sources containing high concentrations of unreacted propellant constituents. Propellants contain energetic compounds such as nitroglycerin (NG) and 2,4-dinitrotoluene (2,4-DNT), both of which are found at firing positions and propellant disposal areas. To quantify the mass of residue remaining from the field-expedient disposal of propellants, two mortar propellants and one howitzer propellant were burned under different field conditions. These conditions included burning on a snow pack, at the bottom of a snow pit, and in a pan surrounded by snow for the mortar propellants and on dry and wet sand for the howitzer propellant. For the mortar propellant, the energetics (NG) remaining after burning in the bowl, on frozen ground, and on snow were 0.21%, 5.2% and 18%, respectively. For the howitzer propellant, the difference in energetics (2,4-DNT) remaining after disposal on wet and dry sand was <0.1%, with the overall residue rate of around 1%, similar to that for the mortar propellant burned in an open container. These tests demonstrate that environmental factors, especially in winter, can play a significant role in the effectiveness of field-expedient disposal of propellants. JF - Journal of Hazardous Materials AU - Walsh, Michael R AU - Walsh, Marianne E AU - Hewitt, Alan D AD - US Army Cold Regions Research and Engineering Laboratory, 72 Lyme Road, Hanover, NH 03755-1290, USA, Michael.Walsh@usace.army.mil Y1 - 2010/01/15/ PY - 2010 DA - 2010 Jan 15 SP - 115 EP - 122 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 173 IS - 1-3 SN - 0304-3894, 0304-3894 KW - Toxicology Abstracts; Environment Abstracts; Pollution Abstracts KW - Propellants KW - Residues KW - Expedient field disposal KW - Military KW - Energetics KW - environmental factors KW - Training KW - Snow KW - burning KW - Environmental factors KW - Nitroglycerin KW - winter KW - Sand KW - Burning KW - P 5000:LAND POLLUTION KW - X 24490:Other KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/744611977?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+%26+Engineering+Geophysics&rft.atitle=A+new+high-sensitivity+subsurface+electromagnetic+sensing+system%3B+Part+I%2C+System+design&rft.au=Sternberg%2C+Ben+K%3BKrichenko%2C+Oleg%3BDvorak%2C+Steven+L&rft.aulast=Sternberg&rft.aufirst=Ben&rft.date=2008-09-01&rft.volume=13&rft.issue=3&rft.spage=247&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+%26+Engineering+Geophysics&rft.issn=10831363&rft_id=info:doi/10.2113%2FJEEG13.3.247 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Nitroglycerin; Sand; Snow; Burning; Environmental factors; environmental factors; winter; Residues; Training; Propellants; Military; burning DO - http://dx.doi.org/10.1016/j.jhazmat.2009.08.056 ER - TY - JOUR T1 - Chemotherapy intensity and toxicity among black and white women with advanced and recurrent endometrial cancer: a Gynecologic Oncology Group Study. AN - 733683704; 19924790 AB - The purpose of this study was to confirm whether black and white women with endometrial cancer are equally tolerant of chemotherapy and identify factors that impact survival. A retrospective review of 169 black women and 982 white women with the International Federation of Gynecologists and Obstetricians stage III, stage IV, or recurrent endometrial carcinoma was performed. All patients received doxorubicin combined with cisplatin. Chemotherapy parameters that were reviewed included relative dose, relative time, and relative dose intensity. Treatment cycles > or =7 were defined as treatment completion. Although black patients were more likely to experience grades 3-4 anemia (20% vs 14%) and genitourinary (5% vs 1%) toxicity, and less likely to experience severe gastrointestinal toxicity (10% vs 17%), the overall incidence of grades 3-4 treatment-related chemotoxicity was the same between the 2 groups (82% vs 82%). There were no differences in the number of cycles received, relative dose (0.57 vs 0.58), relative time (0.77 vs 0.78), or relative dose intensity (0.76 vs 0.76) for black and white patients. Black patients with advanced stage or recurrent endometrial cancer, treated on 4 Gynecologic Oncology Group (GOG) protocols, had similar dose intensity and severe chemotherapy-related toxicity compared with white patients, suggesting that previously described racial disparities in survival among patients in GOG trials may have an novel etiology. JF - Cancer AU - Farley, John H AU - Tian, Chunqiao AU - Rose, G Scott AU - Brown, Carol L AU - Birrer, Michael AU - Risinger, John I AU - Thigpen, J Tate AU - Fleming, Gini F AU - Gallion, Holly H AU - Maxwell, G Larry AD - Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20832, USA. john.farley@us.army.mil Y1 - 2010/01/15/ PY - 2010 DA - 2010 Jan 15 SP - 355 EP - 361 VL - 116 IS - 2 SN - 0008-543X, 0008-543X KW - Doxorubicin KW - 80168379AG KW - Cisplatin KW - Q20Q21Q62J KW - Abridged Index Medicus KW - Index Medicus KW - Randomized Controlled Trials as Topic KW - Drug Administration Schedule KW - Humans KW - Recurrence KW - Female KW - Chemotherapy, Adjuvant KW - European Continental Ancestry Group KW - Endometrial Neoplasms -- pathology KW - Endometrial Neoplasms -- drug therapy KW - African Americans KW - Doxorubicin -- administration & dosage KW - Antineoplastic Combined Chemotherapy Protocols -- administration & dosage KW - Antineoplastic Combined Chemotherapy Protocols -- adverse effects KW - Endometrial Neoplasms -- ethnology KW - Cisplatin -- administration & dosage UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733683704?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+%26+Engineering+Geophysics&rft.atitle=Absolute+calibration+of+EMI+measurements+and+application+to+soil+magnetic+susceptibility+inference&rft.au=Zhang%2C+Beijia%3BO%27Neill%2C+Kevin%3BKong%2C+Jin+Au&rft.aulast=Zhang&rft.aufirst=Beijia&rft.date=2008-09-01&rft.volume=13&rft.issue=3&rft.spage=223&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+%26+Engineering+Geophysics&rft.issn=10831363&rft_id=info:doi/10.2113%2FJEEG13.3.223 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-03-09 N1 - Date created - 2010-01-26 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Clin Cancer Res. 2000 Aug;6(8):2999-3005 [10955777] CA Cancer J Clin. 2008 Mar-Apr;58(2):71-96 [18287387] J Natl Cancer Inst. 2002 Aug 7;94(15):1160-7 [12165641] CA Cancer J Clin. 2002 Nov-Dec;52(6):326-41 [12469762] Cancer. 2003 Jul 1;98(1):176-86 [12833470] Breast Cancer Res Treat. 2003 Sep;81(1):21-31 [14531494] J Clin Oncol. 2003 Oct 15;21(20):3808-13 [14551299] J Clin Oncol. 2003 Nov 15;21(22):4200-6 [14615448] J Clin Oncol. 2004 Jun 1;22(11):2159-66 [15169803] Ann Oncol. 2004 Aug;15(8):1173-8 [15277255] J Clin Oncol. 2004 Oct 1;22(19):3902-8 [15459211] Am J Obstet Gynecol. 1996 Nov;175(5):1246-52 [8942496] Obstet Gynecol. 1996 Dec;88(6):919-26 [8942828] Am J Obstet Gynecol. 1997 Jun;176(6):S229-32 [9215213] Cancer. 1998 Dec 15;83(12):2629-37 [9874471] Am J Public Health. 2004 Dec;94(12):2104-11 [15569961] J Clin Oncol. 2005 Sep 20;23(27):6639-46 [16170171] Gynecol Oncol. 2006 May;101(2):209-13 [16380157] Cancer Nurs. 2006 Jul-Aug;29(4):266-72 [16871092] Cancer. 2006 Nov 1;107(9):2197-205 [17001661] J Clin Oncol. 2007 Feb 10;25(5):517-25 [17290060] Cancer. 2007 Jul 15;110(2):234-43 [17559136] J Clin Oncol. 2007 Oct 1;25(28):4350-7 [17906199] Curr Oncol Rep. 1999 Sep;1(1):54-8 [11122798] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1002/cncr.24769 ER - TY - JOUR T1 - Rapid product analysis and increased sensitivity for quantitative determinations of botulinum neurotoxin proteolytic activity AN - 21246139; 11351082 AB - The ultimate molecular action of botulinum neurotoxin (BoNT) is a Zn-dependent endoproteolytic activity on one of the three SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) proteins. There are seven serotypes (A-G) of BoNT having distinct cleavage sites on the SNARE substrates. The proteolytic activity is located on the N-terminal light chain (Lc) domain and is used extensively as the primary target toward therapeutic development against botulism. Here we describe an improved method using ultra-performance liquid chromatography (UPLC) whereby quantitative data were obtained in 1/10th the time using 1/20th the sample and solvent volumes compared with a widely used high-performance liquid chromatography (HPLC) method. We also synthesized a VAMP (vesicle-associated membrane protein)-based peptide containing an intact V1 motif that was efficiently used as a substrate by BoNT/D Lc. Although serotype C1 cleaves the serotype A substrate at a bond separated by only one residue, we were able to distinguish the two reactions by UPLC. The new method can accurately quantify as low as 7 pmol of the peptide substrates for BoNT serotypes A, B, C1, and D. We also report here that the catalytic efficiency of serotype A can be stimulated 35-fold by the addition of Triton X-100 to the reaction mixture. Combining the use of Triton X-100 with the newly introduced UPLC method, we were able to accurately detect very low levels of proteolytic activity in a very short time. Sensitivity of the assay and accuracy and rapidity of product analysis should greatly augment efforts in therapeutic development. JF - Analytical Biochemistry AU - Rowe, Benjamin AU - Schmidt, James J AU - Smith, Leonard A AU - Ahmed, SAshraf AD - Department of Cell Biology and Biochemistry, Integrated Toxicology Division, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702, USA, syed.ahmed@amedd.army.mil Y1 - 2010/01/15/ PY - 2010 DA - 2010 Jan 15 SP - 188 EP - 193 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 396 IS - 2 SN - 0003-2697, 0003-2697 KW - Microbiology Abstracts B: Bacteriology KW - HPLC KW - UPLC KW - Botulinum neurotoxin KW - Protease KW - Product analysis KW - Proteolysis KW - High-performance liquid chromatography KW - Light chains KW - Serotypes KW - Data processing KW - Botulism KW - Solvents KW - Clostridium botulinum KW - Development KW - N-Ethylmaleimide-sensitive protein KW - SNAP receptors KW - Liquid chromatography KW - Botulinum toxin KW - J 02300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21246139?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytical+Biochemistry&rft.atitle=Rapid+product+analysis+and+increased+sensitivity+for+quantitative+determinations+of+botulinum+neurotoxin+proteolytic+activity&rft.au=Rowe%2C+Benjamin%3BSchmidt%2C+James+J%3BSmith%2C+Leonard+A%3BAhmed%2C+SAshraf&rft.aulast=Rowe&rft.aufirst=Benjamin&rft.date=2010-01-15&rft.volume=396&rft.issue=2&rft.spage=188&rft.isbn=&rft.btitle=&rft.title=Analytical+Biochemistry&rft.issn=00032697&rft_id=info:doi/10.1016%2Fj.ab.2009.09.034 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - High-performance liquid chromatography; Proteolysis; Light chains; Data processing; Serotypes; Botulism; Liquid chromatography; Solvents; Development; Botulinum toxin; N-Ethylmaleimide-sensitive protein; SNAP receptors; Clostridium botulinum DO - http://dx.doi.org/10.1016/j.ab.2009.09.034 ER - TY - CPAPER T1 - The Enemy of My Enemy is My Friend: Okinawan Identity and Military Government Policy in Occupied Okinawa, April 1945 T2 - 8th Annual Hawaii International Conference on Arts and Humanities AN - 42328489; 5650108 JF - 8th Annual Hawaii International Conference on Arts and Humanities AU - Short, Courtney Y1 - 2010/01/13/ PY - 2010 DA - 2010 Jan 13 KW - Japan, Nansei-shoto, Okinawa KW - Government policy KW - Military KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42328489?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=8th+Annual+Hawaii+International+Conference+on+Arts+and+Humanities&rft.atitle=The+Enemy+of+My+Enemy+is+My+Friend%3A+Okinawan+Identity+and+Military+Government+Policy+in+Occupied+Okinawa%2C+April+1945&rft.au=Short%2C+Courtney&rft.aulast=Short&rft.aufirst=Courtney&rft.date=2010-01-13&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=8th+Annual+Hawaii+International+Conference+on+Arts+and+Humanities&rft.issn=&rft_id=info:doi/ L2 - http://www.hichumanities.org/2010%20Final%20AH%20Program.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Flood Risk Assessment of Complex Riverine Systems AN - 907153564; 14142102 AB - For over two decades, the U.S. Army Corps of Engineers has required that all of their planning processes address the Nation's water resources needs in a systems context. Corps policy requires that all flood risk management studies adopt risk analysis. Although the Corps has a requirement for systems approaches using risk analysis, there is little guidance and few tools to support these requirements. For this reason, the Corps' Institute for Water Resources sponsored investigations into the development of a new application to analyze complex riverine systems while implementing the flood risk analysis and systems requirements. This new application, currently called HEC- FRM (Flood Risk Management), will eventually become the next generation of the Hydrologic Engineering Center's Flood Damage Analysis (HEC-FDA) model. It will include a systems approach, event-based sampling, the ability to do scenario analysis, and structure-by-structure, cost, non-structural, loss-of-life, and agricultural damage analyses. The tool will accommodate many, if not all, of the recommendations that the Corps concurred with from the National Research Council report on the Corps' implementation of risk analysis for flood damage reduction (NRC, 2000), and it will also aide in implementing the Chief of Engineers' Actions for Change. This presentation will introduce the modeling concepts including sampling and solution techniques, uncertainty definitions, and system component fragility and performance interactions/relationships. JF - Watershed Management 2010: Innovations in Watershed Management under Land Use and Climate Change AU - Harris, David "Jeff" AU - Dunn, Christopher N AU - Deering, Michael K AD - Chief, Hydrology and Hydraulics Technology Division, U.S. Army Corps of Engineers, Institute for Water Resources, Hydrologic Engineering Center, 609 Second Street, Davis, CA 95616. Y1 - 2010///0, PY - 2010 DA - 0, 2010 SP - 236 EP - 247 KW - Aqualine Abstracts; Water Resources Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Risk Abstracts KW - Floods KW - Risk management KW - River systems KW - Water resources KW - Risk assessment KW - Resource management KW - Climate change KW - Freshwater KW - Risks KW - Hydrologic Models KW - Assessments KW - Planning KW - Sampling KW - River basin management KW - Damage KW - Risk analysis KW - River discharge KW - Flood Damage KW - Risk KW - USA KW - Resource development KW - National planning KW - Water Resources KW - SW 4020:Evaluation process KW - AQ 00005:Underground Services and Water Use KW - R2 23070:Economics, organization KW - Q2 09124:Coastal zone management UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/907153564?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Watershed+Management+2010%3A+Innovations+in+Watershed+Management+under+Land+Use+and+Climate+Change&rft.atitle=Flood+Risk+Assessment+of+Complex+Riverine+Systems&rft.au=Harris%2C+David+%22Jeff%22%3BDunn%2C+Christopher+N%3BDeering%2C+Michael+K&rft.aulast=Pasion&rft.aufirst=Leonard&rft.date=2008-09-01&rft.volume=13&rft.issue=3&rft.spage=193&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+%26+Engineering+Geophysics&rft.issn=10831363&rft_id=info:doi/10.2113%2FJEEG13.3.193 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2017-02-01 N1 - SubjectsTermNotLitGenreText - Resource management; Floods; Climate change; River discharge; Water resources; Resource development; River basin management; National planning; Risks; Risk assessment; Risk management; Risk analysis; Damage; Risk; Hydrologic Models; Assessments; Planning; Sampling; Flood Damage; Water Resources; USA; Freshwater DO - http://dx.doi.org/10.1061/41148(389)22 ER - TY - JOUR T1 - Incorporating Climate Change Impacts into the Columbia River Treaty 2014/2024 Review AN - 902348485; 14142089 AB - The U. S. Army Corps of Engineers (USACE) is undertaking a series of studies to support a pending decision by the United States pertaining to the future of the Columbia River Treaty with Canada. The Treaty, ratified in 1964, is an agreement between the United States and Canada to provide flood control and power benefits for both countries. In these studies, information will be developed and alternatives evaluated that provide the basis for long-term recommendations pertaining to the future of the Treaty. Assumptions drawn regarding potential future climate changes and associated hydrologic impacts could have very significant influence on alternative Treaty strategies. For several decades climate scientists have provided an increasing array of knowledge and information on climate impacts. Climatic phenomena, such as summer and wintertime droughts, floods and wind storms, have greatly affected the Pacific Northwest in the last several decades. Observed data in the West is already showing signs of global warming - reductions in spring snowpack, earlier spring snowmelt, increased runoff in winter and less runoff in summer. These shifts may potentially increase flood risks in the early spring, and change the timing and volume of water in spring and early summer available for reservoir refill. Different parts of a basin may be affected differently by warming so that high elevation snowpack may experience minor impacts while low elevation sites may experience major changes Water resource managers have struggled to understand how to incorporate the knowledge provided by science into their planning and operations. This paper discusses a decision-making framework to bridge the gap between climate science and water management for the Columbia River Treaty 2014/2024 Review. The decision framework must be robust enough to accommodate risk characterization, screening and prioritization while allowing for adaptive management strategies that avoid maladaptations. Maladaptions are decisions that prevent or constrain the ability of others to manage, reduce or otherwise adapt to the effects of climate change in the future. Modeling systems used by the team will be capable of incorporating multi-objective analyses and alternative assessments running numerous future climate scenarios in physically based hydrologic, reservoir and hydraulic models that will ultimately support the decision-making framework. JF - Watershed Management 2010: Innovations in Watershed Management under Land Use and Climate Change AU - Vaddey, Seshagirirao AD - U.S. Army Corps of Engineers - Portland District, 333 SW 1 super(st) Ave., Portland, OR 97204. Y1 - 2010///0, PY - 2010 DA - 0, 2010 SP - 91 EP - 102 KW - Aqualine Abstracts; Water Resources Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Sustainability Science Abstracts KW - Climate change KW - Columbia River KW - Agreements and treaties KW - Snowpack KW - Reservoir KW - Flood control KW - Resource management KW - Basins KW - Water resources KW - Freshwater KW - Decision Making KW - INE, USA, Pacific Northwest KW - Treaties KW - INE, USA, Columbia Estuary KW - Floods KW - Reservoirs KW - River basin management KW - Rivers KW - Climates KW - ANW, Canada KW - Greenhouse effect KW - Risk KW - Water management KW - Reviews KW - summer KW - Runoff KW - Q5 08503:Characteristics, behavior and fate KW - AQ 00006:Sewage KW - M3 1010:Issues in Sustainable Development KW - SW 4020:Evaluation process UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/902348485?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Watershed+Management+2010%3A+Innovations+in+Watershed+Management+under+Land+Use+and+Climate+Change&rft.atitle=Incorporating+Climate+Change+Impacts+into+the+Columbia+River+Treaty+2014%2F2024+Review&rft.au=Vaddey%2C+Seshagirirao&rft.aulast=Vaddey&rft.aufirst=Seshagirirao&rft.date=2010-01-01&rft.volume=&rft.issue=&rft.spage=91&rft.isbn=9780784411438&rft.btitle=&rft.title=Watershed+Management+2010%3A+Innovations+in+Watershed+Management+under+Land+Use+and+Climate+Change&rft.issn=&rft_id=info:doi/10.1061%2F41148%28389%299 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2017-02-01 N1 - SubjectsTermNotLitGenreText - Flood control; Reservoir; Resource management; Water management; Climate change; Water resources; Greenhouse effect; River basin management; Runoff; Floods; Reviews; Basins; summer; Reservoirs; Snowpack; Rivers; Risk; Climates; Decision Making; Treaties; INE, USA, Columbia Estuary; ANW, Canada; INE, USA, Pacific Northwest; Freshwater DO - http://dx.doi.org/10.1061/41148(389)9 ER - TY - JOUR T1 - Impacts of complex terrain on evapotranspiration within a tropical alpine valley in the Peruvian Andes AN - 886908221; 2011-073175 JF - Proceedings of the Annual Eastern Snow Conference AU - Hellstrom, Robert A AU - Higgins, Aimee AU - Ferris, Derek AU - Mark, Bryan AU - Levia, Delphis A2 - Hellstrom, Robert A. A2 - Frankenstein, Susan Y1 - 2010 PY - 2010 DA - 2010 SP - 131 EP - 155 PB - Eastern Snow Conference, [varies] VL - 67 SN - 0424-1932, 0424-1932 KW - water KW - soils KW - hydrology KW - Cordillera Blanca KW - Andes KW - land cover KW - terrestrial environment KW - evapotranspiration KW - temperature KW - models KW - spatial variations KW - South America KW - El Nino Southern Oscillation KW - humidity KW - Llanganuco Valley KW - solar radiation KW - Peru KW - Northern Andes KW - diurnal variations KW - meteorology KW - winds KW - alpine environment KW - 21:Hydrogeology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/886908221?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Proceedings+of+the+Annual+Eastern+Snow+Conference&rft.atitle=Impacts+of+complex+terrain+on+evapotranspiration+within+a+tropical+alpine+valley+in+the+Peruvian+Andes&rft.au=Hellstrom%2C+Robert+A%3BHiggins%2C+Aimee%3BFerris%2C+Derek%3BMark%2C+Bryan%3BLevia%2C+Delphis&rft.aulast=Hellstrom&rft.aufirst=Robert&rft.date=2010-01-01&rft.volume=67&rft.issue=&rft.spage=131&rft.isbn=0920081320&rft.btitle=&rft.title=Proceedings+of+the+Annual+Eastern+Snow+Conference&rft.issn=04241932&rft_id=info:doi/ L2 - http://www.easternsnow.org/ LA - English DB - GeoRef N1 - Conference title - 67th annual Eastern snow conference N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Number of references - 65 N1 - Document feature - illus. incl. 3 tables, sketch map N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - alpine environment; Andes; Cordillera Blanca; diurnal variations; El Nino Southern Oscillation; evapotranspiration; humidity; hydrology; land cover; Llanganuco Valley; models; Northern Andes; Peru; soils; solar radiation; South America; spatial variations; temperature; terrestrial environment; water; meteorology; winds ER - TY - JOUR T1 - Satellite identification of transient snowline variation during the melt season for mass balance assessment, Taku and Brady Glacier, Alaska AN - 886908218; 2011-073168 JF - Proceedings of the Annual Eastern Snow Conference AU - Pelto, M S A2 - Hellstrom, Robert A. A2 - Frankenstein, Susan Y1 - 2010 PY - 2010 DA - 2010 SP - 51 EP - 60 PB - Eastern Snow Conference, [varies] VL - 67 SN - 0424-1932, 0424-1932 KW - United States KW - Taku Glacier KW - ablation KW - glaciers KW - rates KW - satellite methods KW - Brady Glacier KW - melting KW - Alaska Panhandle KW - mass balance KW - snow KW - Alaska KW - glacial geology KW - remote sensing KW - 24:Quaternary geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/886908218?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Proceedings+of+the+Annual+Eastern+Snow+Conference&rft.atitle=Satellite+identification+of+transient+snowline+variation+during+the+melt+season+for+mass+balance+assessment%2C+Taku+and+Brady+Glacier%2C+Alaska&rft.au=Pelto%2C+M+S&rft.aulast=Pelto&rft.aufirst=M&rft.date=2010-01-01&rft.volume=67&rft.issue=&rft.spage=51&rft.isbn=0920081320&rft.btitle=&rft.title=Proceedings+of+the+Annual+Eastern+Snow+Conference&rft.issn=04241932&rft_id=info:doi/ L2 - http://www.easternsnow.org/ LA - English DB - GeoRef N1 - Conference title - 67th annual Eastern snow conference N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Number of references - 14 N1 - Document feature - illus. incl. sketch map N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - ablation; Alaska; Alaska Panhandle; Brady Glacier; glacial geology; glaciers; mass balance; melting; rates; remote sensing; satellite methods; snow; Taku Glacier; United States ER - TY - JOUR T1 - Polar lessons for our International Polar Year (IPY, 2007-2009) from the Internationl Geophysical Year (IGY, 1957-1958); some Canadian examples AN - 886908216; 2011-073166 JF - Proceedings of the Annual Eastern Snow Conference AU - Ecclestone, M A AU - Cogley, J Graham AU - Adams, W P A2 - Hellstrom, Robert A. A2 - Frankenstein, Susan Y1 - 2010 PY - 2010 DA - 2010 SP - 33 EP - 39 PB - Eastern Snow Conference, [varies] VL - 67 SN - 0424-1932, 0424-1932 KW - history KW - programs KW - International Geophysical Year 1957-58 KW - IPY 2007-08 Education, Outreach and Communication Publications KW - expeditions KW - Canada KW - mass balance KW - International Polar Year 2007-08 KW - Arctic region KW - glaciers KW - research KW - 15:Miscellaneous UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/886908216?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Proceedings+of+the+Annual+Eastern+Snow+Conference&rft.atitle=Polar+lessons+for+our+International+Polar+Year+%28IPY%2C+2007-2009%29+from+the+Internationl+Geophysical+Year+%28IGY%2C+1957-1958%29%3B+some+Canadian+examples&rft.au=Ecclestone%2C+M+A%3BCogley%2C+J+Graham%3BAdams%2C+W+P&rft.aulast=Ecclestone&rft.aufirst=M&rft.date=2010-01-01&rft.volume=67&rft.issue=&rft.spage=33&rft.isbn=0920081320&rft.btitle=&rft.title=Proceedings+of+the+Annual+Eastern+Snow+Conference&rft.issn=04241932&rft_id=info:doi/ L2 - http://www.easternsnow.org/ LA - English DB - GeoRef N1 - Conference title - 67th annual Eastern snow conference N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Number of references - 18 N1 - Document feature - illus. N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - Arctic region; Canada; expeditions; glaciers; history; International Geophysical Year 1957-58; International Polar Year 2007-08; IPY 2007-08 Education, Outreach and Communication Publications; mass balance; programs; research ER - TY - JOUR T1 - Skykomish River, Washington impact of ongoing glacier retreat on streamflow AN - 886908213; 2011-073165 JF - Proceedings of the Annual Eastern Snow Conference AU - Pelto, M S A2 - Hellstrom, Robert A. A2 - Frankenstein, Susan Y1 - 2010 PY - 2010 DA - 2010 SP - 23 EP - 32 PB - Eastern Snow Conference, [varies] VL - 67 SN - 0424-1932, 0424-1932 KW - United States KW - hydrology KW - Washington KW - Snohomish County Washington KW - rivers and streams KW - watersheds KW - glaciers KW - atmospheric precipitation KW - King County Washington KW - deglaciation KW - climate change KW - Cascade Range KW - streamflow KW - hydrographs KW - mass balance KW - runoff KW - northern Cascade Range KW - climate effects KW - Skykomish River basin KW - west-central Washington KW - discharge KW - meltwater KW - 21:Hydrogeology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/886908213?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Proceedings+of+the+Annual+Eastern+Snow+Conference&rft.atitle=Skykomish+River%2C+Washington+impact+of+ongoing+glacier+retreat+on+streamflow&rft.au=Pelto%2C+M+S&rft.aulast=Pelto&rft.aufirst=M&rft.date=2010-01-01&rft.volume=67&rft.issue=&rft.spage=23&rft.isbn=0920081320&rft.btitle=&rft.title=Proceedings+of+the+Annual+Eastern+Snow+Conference&rft.issn=04241932&rft_id=info:doi/ L2 - http://www.easternsnow.org/ LA - English DB - GeoRef N1 - Conference title - 67th annual Eastern snow conference N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Number of references - 17 N1 - Document feature - illus. incl. sketch map N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - atmospheric precipitation; Cascade Range; climate change; climate effects; deglaciation; discharge; glaciers; hydrographs; hydrology; King County Washington; mass balance; meltwater; northern Cascade Range; rivers and streams; runoff; Skykomish River basin; Snohomish County Washington; streamflow; United States; Washington; watersheds; west-central Washington ER - TY - JOUR T1 - 67th annual Eastern snow conference AN - 886908207; 2011-073162 JF - Proceedings of the Annual Eastern Snow Conference A2 - Hellstrom, Robert A. A2 - Frankenstein, Susan Y1 - 2010 PY - 2010 DA - 2010 SP - 209 PB - Eastern Snow Conference, [varies] VL - 67 SN - 0424-1932, 0424-1932 KW - snow cover KW - symposia KW - ice KW - snow KW - climate change KW - climate KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/886908207?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Proceedings+of+the+Annual+Eastern+Snow+Conference&rft.atitle=67th+annual+Eastern+snow+conference&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2008-09-01&rft.volume=13&rft.issue=3&rft.spage=147&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+%26+Engineering+Geophysics&rft.issn=10831363&rft_id=info:doi/10.2113%2FJEEG13.3.147 L2 - http://www.easternsnow.org/ LA - English DB - GeoRef N1 - Conference title - 67th annual Eastern snow conference N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Document feature - illus. incl. tables, sketch maps N1 - SuppNotes - Individual papers within scope are cited separately N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - climate; climate change; ice; snow; snow cover; symposia ER - TY - JOUR T1 - Topography data on Mars; optimizing its collection and application using laser scanning AN - 881450308; 2011-062288 JF - Geophysical Research Abstracts AU - Bulmer, Mark AU - Finnegan, David AU - Anonymous Y1 - 2010 PY - 2010 DA - 2010 SP - EGU2010 EP - 7110 PB - Copernicus GmbH on behalf of the European Geosciences Union (EGU), Katlenburg-Lindau VL - 12 SN - 1029-7006, 1029-7006 KW - United States KW - laser methods KW - data acquisition KW - optimization KW - Mars KW - altimetry KW - laser scanning KW - terrestrial analogs KW - terrestrial planets KW - California KW - planets KW - topography KW - Mojave Desert KW - geomorphology KW - accuracy KW - instruments KW - remote sensing KW - airborne methods KW - 04:Extraterrestrial geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/881450308?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Geophysical+Research+Abstracts&rft.atitle=Topography+data+on+Mars%3B+optimizing+its+collection+and+application+using+laser+scanning&rft.au=Bulmer%2C+Mark%3BFinnegan%2C+David%3BAnonymous&rft.aulast=Bulmer&rft.aufirst=Mark&rft.date=2010-01-01&rft.volume=12&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Geophysical+Research+Abstracts&rft.issn=10297006&rft_id=info:doi/ L2 - http://www.copernicus.org/EGU/gra/gra.html LA - English DB - GeoRef N1 - Conference title - European Geosciences Union general assembly 2010 N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - accuracy; airborne methods; altimetry; California; data acquisition; geomorphology; instruments; laser methods; laser scanning; Mars; Mojave Desert; optimization; planets; remote sensing; terrestrial analogs; terrestrial planets; topography; United States ER - TY - JOUR T1 - Wave setup over a Pacific Island fringing reef AN - 877848526; 2011-060858 AB - Measurements obtained across a shore-attached, fringing reef on the southeast coast of the island of Guam are examined to determine the relationship between incident waves and wave-driven setup during storm and nonstorm conditions. Wave setup on the reef flat correlates well (r > 0.95) and scales near the shore as approximately 35% of the incident root mean square wave height in 8 m water depth. Waves generated by tropical storm Man-Yi result in a 1.3 m setup during the peak of the storm. Predictions based on traditional setup theory (steady state, inviscid cross-shore momentum and depth-limited wave breaking) and an idealized model of localized wave breaking at the fore reef are in agreement with the observations. The reef flat setup is used to estimate a similarity parameter at breaking that is in agreement with observations from a steeply sloping sandy beach. A weak ( approximately 10%) increase in setup is observed across the reef flat during wave events. The inclusion of bottom stress in the cross-shore momentum balance may account for a portion of this signal, but this assessment is inconclusive as the reef flat currents in some cases are in the wrong direction to account for the increase. An independent check of fringing reef setup dynamics is carried out for measurements at the neighboring island of Saipan with good agreement. JF - Journal of Geophysical Research AU - Vetter, O AU - Becker, J M AU - Merrifield, M A AU - Pequignet, A C AU - Aucan, J AU - Boc, S J AU - Pollock, C E Y1 - 2010 PY - 2010 DA - 2010 EP - Citation C12066 PB - American Geophysical Union, Washington, DC VL - 115 IS - C12 SN - 0148-0227, 0148-0227 KW - reefs KW - West Pacific KW - Anthozoa KW - Micronesia KW - Invertebrata KW - storms KW - ocean floors KW - Northwest Pacific KW - Mariana Islands KW - breaking waves KW - Ipan Reef KW - stress KW - Man-Yi KW - damage KW - prediction KW - tropical storms KW - North Pacific KW - Guam KW - Pacific Ocean KW - ocean waves KW - Oceania KW - coastal environment KW - Cnidaria KW - bathymetry KW - 07:Oceanography UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/877848526?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Geophysical+Research&rft.atitle=Wave+setup+over+a+Pacific+Island+fringing+reef&rft.au=Vetter%2C+O%3BBecker%2C+J+M%3BMerrifield%2C+M+A%3BPequignet%2C+A+C%3BAucan%2C+J%3BBoc%2C+S+J%3BPollock%2C+C+E&rft.aulast=Vetter&rft.aufirst=O&rft.date=2010-01-01&rft.volume=115&rft.issue=C12&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Journal+of+Geophysical+Research&rft.issn=01480227&rft_id=info:doi/10.1029%2F2010JC006455 L2 - http://www.agu.org/journals/jgr/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by, and/or abstract, Copyright, American Geophysical Union, Washington, DC, United States N1 - Date revised - 2011-01-01 N1 - Number of references - 27 N1 - PubXState - DC N1 - Document feature - illus. incl. 1 table, sketch map N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - Anthozoa; bathymetry; breaking waves; Cnidaria; coastal environment; damage; Guam; Invertebrata; Ipan Reef; Man-Yi; Mariana Islands; Micronesia; North Pacific; Northwest Pacific; ocean floors; ocean waves; Oceania; Pacific Ocean; prediction; reefs; storms; stress; tropical storms; West Pacific DO - http://dx.doi.org/10.1029/2010JC006455 ER - TY - JOUR T1 - Production velocity of sea spray droplets AN - 877848519; 2011-060857 AB - The sea spray generation function dF/dr (sub 0) predicts the rate at which droplets of initial radius r (sub 0) are produced at the sea surface. Because this function is not readily measurable in the marine environment, however, it is often inferred from measurements of the near-surface droplet concentration, C(r (sub 0) ), through an assumed velocity scale, the effective spray production velocity. This paper proceeds in reverse, though: It uses a reliable estimate of dF/dr (sub 0) and 13 sets of measurements of C(r (sub 0) ) over the ocean to calculate the implied effective production velocity, V (sub eff) , for droplets with initial radii r (sub 0) from 5 to 300 mu m. It then compares these V (sub eff) values with four candidate expressions for this production velocity: the dry-deposition velocity, V (sub Dh) ; the mean wind speed at the significant wave amplitude (A (sub 1/3) ), U (sub A1/3) ; the standard deviation in vertical droplet velocity, sigma (sub wd) ; and laboratory measurements of the ejection velocity of jet droplets, V (sub ej) . The velocity scales U (sub A1/3) and V (sub ej) agree best with the implied V (sub eff) values for 20< or =r (sub 0) < or =300 mu m. The deposition velocity, V (sub Dh) , which is the velocity most commonly used in this application, agrees worst with the V (sub eff) values. For droplets with r (sub 0) less than about 20 mu m, the analysis also rejects the main hypothesis: that dF/dr (sub 0) and C(r (sub 0) ) can be related through a velocity scale. These smaller droplets simply have residence times that are too long for spray concentrations to be in local equilibrium with the spray production rate. JF - Journal of Geophysical Research AU - Andreas, Edgar L AU - Jones, Kathleen F AU - Fairall, Christopher W Y1 - 2010 PY - 2010 DA - 2010 EP - Citation C12065 PB - American Geophysical Union, Washington, DC VL - 115 IS - C12 SN - 0148-0227, 0148-0227 KW - sea water KW - sea spray KW - moisture KW - prediction KW - atmosphere KW - air-sea interface KW - measurement KW - droplets KW - deposition KW - velocity KW - aerosols KW - air KW - 07:Oceanography UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/877848519?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Geophysical+Research&rft.atitle=Production+velocity+of+sea+spray+droplets&rft.au=Andreas%2C+Edgar+L%3BJones%2C+Kathleen+F%3BFairall%2C+Christopher+W&rft.aulast=Andreas&rft.aufirst=Edgar&rft.date=2010-01-01&rft.volume=115&rft.issue=C12&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Journal+of+Geophysical+Research&rft.issn=01480227&rft_id=info:doi/10.1029%2F2010JC006458 L2 - http://www.agu.org/journals/jgr/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by, and/or abstract, Copyright, American Geophysical Union, Washington, DC, United States N1 - Date revised - 2011-01-01 N1 - Number of references - 70 N1 - PubXState - DC N1 - Document feature - illus. incl. 1 table N1 - SuppNotes - Includes appendix N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - aerosols; air; air-sea interface; atmosphere; deposition; droplets; measurement; moisture; prediction; sea spray; sea water; velocity DO - http://dx.doi.org/10.1029/2010JC006458 ER - TY - JOUR T1 - Climate monitoring in Glacier Bay National Park and Preserve; capturing climate change indicators AN - 877847073; 2011-059035 JF - ERDC/CRREL Letter Report AU - Lawson, Daniel E AU - Klaar, Megan AU - Finnegan, David C AU - Campbell, Seth Y1 - 2010 PY - 2010 DA - 2010 SP - 21 PB - U. S. Army Cold Regions Research and Engineering Laboratory, Hanover, NH KW - United States KW - hydrology KW - monitoring KW - Quaternary KW - Juneau Quadrangle KW - ice cover KW - glaciers KW - Glacier Bay National Park KW - paleoclimatology KW - deglaciation KW - climate change KW - Cenozoic KW - ice KW - climate effects KW - Skagway Quadrangle KW - Alaska KW - glacial geology KW - 24:Quaternary geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/877847073?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/GeoRef&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=Lawson%2C+Daniel+E%3BKlaar%2C+Megan%3BFinnegan%2C+David+C%3BCampbell%2C+Seth&rft.aulast=Lawson&rft.aufirst=Daniel&rft.date=2010-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=Climate+monitoring+in+Glacier+Bay+National+Park+and+Preserve%3B+capturing+climate+change+indicators&rft.title=Climate+monitoring+in+Glacier+Bay+National+Park+and+Preserve%3B+capturing+climate+change+indicators&rft.issn=&rft_id=info:doi/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Number of references - 9 N1 - PubXState - NH N1 - Document feature - illus. N1 - SuppNotes - Includes 2 appendices N1 - Last updated - 2012-06-07 N1 - CODEN - #05693 N1 - SubjectsTermNotLitGenreText - Alaska; Cenozoic; climate change; climate effects; deglaciation; glacial geology; Glacier Bay National Park; glaciers; hydrology; ice; ice cover; Juneau Quadrangle; monitoring; paleoclimatology; Quaternary; Skagway Quadrangle; United States ER - TY - JOUR T1 - Paleoclimate of the last 10,000 years, Glacier Bay National Park and Preserve; progress understanding climate change in southeast Alaska AN - 869790028; 2011-048458 JF - ERDC/CRREL Letter Report AU - Lawson, Daniel E AU - Wiles, Greg AU - Wiesenberg, Nicholas Y1 - 2010 PY - 2010 DA - 2010 SP - 27 PB - U. S. Army Cold Regions Research and Engineering Laboratory, Hanover, NH KW - United States KW - Quaternary KW - Juneau Quadrangle KW - glaciers KW - Glacier Bay National Park KW - paleoclimatology KW - Holocene KW - climate change KW - Cenozoic KW - ice movement KW - southeastern Alaska KW - Neoglacial KW - mass balance KW - Glacier Bay KW - Skagway Quadrangle KW - Alaska KW - glacial geology KW - 24:Quaternary geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/869790028?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/GeoRef&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=Lawson%2C+Daniel+E%3BWiles%2C+Greg%3BWiesenberg%2C+Nicholas&rft.aulast=Lawson&rft.aufirst=Daniel&rft.date=2010-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=Paleoclimate+of+the+last+10%2C000+years%2C+Glacier+Bay+National+Park+and+Preserve%3B+progress+understanding+climate+change+in+southeast+Alaska&rft.title=Paleoclimate+of+the+last+10%2C000+years%2C+Glacier+Bay+National+Park+and+Preserve%3B+progress+understanding+climate+change+in+southeast+Alaska&rft.issn=&rft_id=info:doi/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Number of references - 59 N1 - PubXState - NH N1 - Document feature - illus. incl. 2 sketch maps N1 - SuppNotes - NSF Grant ATM-0902806; annual report 2010 N1 - Last updated - 2012-06-07 N1 - CODEN - #05693 N1 - SubjectsTermNotLitGenreText - Alaska; Cenozoic; climate change; glacial geology; Glacier Bay; Glacier Bay National Park; glaciers; Holocene; ice movement; Juneau Quadrangle; mass balance; Neoglacial; paleoclimatology; Quaternary; Skagway Quadrangle; southeastern Alaska; United States ER - TY - JOUR T1 - Effects of a New Waste-Processing By-product on Soil and Vegetation at Fort Campbell, Tennessee AN - 867739739; 14586141 AB - A garbage-processing technology has been developed that sterilizes and separates inorganic and organic components of municipal solid waste. A study was initiated to evaluate the uncomposted organic by-product of this process as a soil amendment for establishing native prairie grasses on disturbed Army training lands. The waste was incorporated into a silt loam soil at Fort Campbell Military Reservation in the central United States. The waste material was applied at rates of 0, 4.5, 9, 18, and 36Mgh super(-1) and seeded with native prairie grasses to assess its effects on vegetation for two growing seasons, with an additional unseeded control treatment for comparison to natural recovery. Treatments receiving the highest rate of application had significantly more native grass basal cover and percent composition than the controls. Plant phosphorus accumulation increased significantly with increasing pulp application. Soil phosphorus and lead concentrations increased in the top 10cm of the highest application rates where pulp was mixed in the soil. Because minimal environmental effects were detected and the pulp improved perennial grass establishment and nutrition at the 36Mgh super(-1) rate, land application should be considered a viable and beneficial alternative to current waste-management practices. JF - Communications in Soil Science and Plant Analysis AU - Busby, R R AU - Gebhart, D L AU - Torbert, HA AU - Dawson, JO AU - Bollero, G A AU - Potter, K N AU - Curtin AD - U.S. Army Engineer Research and Development Center, Construction Engineering Research Laboratory, Champaign, Illinois, USA Y1 - 2010/01// PY - 2010 DA - Jan 2010 SP - 250 EP - 266 PB - Taylor & Francis Group Ltd., 2 Park Square Oxford OX14 4RN UK VL - 41 IS - 3 SN - 0010-3624, 0010-3624 KW - Pollution Abstracts KW - Soil KW - USA, Tennessee KW - Grasses KW - Byproducts KW - prairies KW - Plants KW - Phosphorus KW - Vegetation KW - Lead KW - Municipal solid wastes KW - P 4000:WASTE MANAGEMENT UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/867739739?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Communications+in+Soil+Science+and+Plant+Analysis&rft.atitle=Effects+of+a+New+Waste-Processing+By-product+on+Soil+and+Vegetation+at+Fort+Campbell%2C+Tennessee&rft.au=Busby%2C+R+R%3BGebhart%2C+D+L%3BTorbert%2C+HA%3BDawson%2C+JO%3BBollero%2C+G+A%3BPotter%2C+K+N%3BCurtin&rft.aulast=Busby&rft.aufirst=R&rft.date=2010-01-01&rft.volume=41&rft.issue=3&rft.spage=250&rft.isbn=&rft.btitle=&rft.title=Communications+in+Soil+Science+and+Plant+Analysis&rft.issn=00103624&rft_id=info:doi/10.1080%2F00103620903460773 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-05-01 N1 - Number of references - 35 N1 - Last updated - 2013-12-04 N1 - SubjectsTermNotLitGenreText - Soil; Grasses; prairies; Byproducts; Phosphorus; Plants; Vegetation; Municipal solid wastes; Lead; USA, Tennessee DO - http://dx.doi.org/10.1080/00103620903460773 ER - TY - JOUR T1 - Universal Glucose Models for Predicting Subcutaneous Glucose Concentration in Humans AN - 867733626; 14642191 AB - This paper tests the hypothesis that a "universal," data-driven model can be developed based on glucose data from one diabetic subject, and subsequently applied to predict subcutaneous glucose concentrations of other subjects, even of those with different types of diabetes. We employed three separate studies, each utilizing a different continuous glucose monitoring (CGM) device, to verify the model's universality. Two out of the three studies involved subjects with type 1 diabetes and the other one with type 2 diabetes. We first filtered the subcutaneous glucose concentration data by imposing constraints on their rate of change. Then, using the filtered data, we developed data-driven autoregressive models of order 30, and used them to make short-term, 30-min-ahead glucose-concentration predictions. We used same-subject model predictions as a reference for comparisons against cross-subject and cross-study model predictions, which were evaluated using the root-mean-squared error (RMSE) and Clarke error grid analysis (EGA). We found that, for each studied subject, the average cross-subject and cross-study RMSEs of the predictions were small and indistinguishable from those obtained with the same-subject models. These observations were corroborated by EGA, where better than 99.0% of the paired sensor-predicted glucose concentrations lay in the clinically acceptable zone A. In addition, the predictive capability of the models was found not to be affected by diabetes type, subject age, CGM device, and interindividual differences. We conclude that it is feasible to develop universal glucose models that allow for clinical use of predictive algorithms and CGM devices for proactive therapy of diabetic patients. JF - IEEE Transactions on Information Technology in Biomedicine AU - Gani, Adiwinata AU - Gribok, Andrei V AU - Lu, Yinghui AU - Ward, WKenneth AU - Vigersky, Robert A AU - Reifman, Jaques AD - Bioinformatics Cell, Telemedicine and Advanced Technology Research Center, U.S. Army Medical Research and Materiel Command, Fort Detrick, USA Y1 - 2010/01// PY - 2010 DA - Jan 2010 SP - 157 EP - 165 PB - Institute of Electrical and Electronics Engineers, Inc., 3 Park Avenue, 17th Fl New York NY 10016-5997 USA VL - 14 IS - 1 SN - 1089-7771, 1089-7771 KW - Biotechnology and Bioengineering Abstracts KW - Diabetes mellitus KW - Age KW - Data processing KW - Glucose KW - Algorithms KW - Models KW - W 30960:Bioinformatics & Computer Applications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/867733626?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=IEEE+Transactions+on+Information+Technology+in+Biomedicine&rft.atitle=Universal+Glucose+Models+for+Predicting+Subcutaneous+Glucose+Concentration+in+Humans&rft.au=Gani%2C+Adiwinata%3BGribok%2C+Andrei+V%3BLu%2C+Yinghui%3BWard%2C+WKenneth%3BVigersky%2C+Robert+A%3BReifman%2C+Jaques&rft.aulast=Gani&rft.aufirst=Adiwinata&rft.date=2010-01-01&rft.volume=14&rft.issue=1&rft.spage=157&rft.isbn=&rft.btitle=&rft.title=IEEE+Transactions+on+Information+Technology+in+Biomedicine&rft.issn=10897771&rft_id=info:doi/10.1109%2FTITB.2009.2034141 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-05-01 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Diabetes mellitus; Age; Data processing; Algorithms; Glucose; Models DO - http://dx.doi.org/10.1109/TITB.2009.2034141 ER - TY - JOUR T1 - Identification of Essential Filovirion-associated Host Factors by Serial Proteomic Analysis and RNAi Screen AN - 864951181; 14046120 AB - An assessment of the total protein composition of filovirus (ebolavirus and marburgvirus) virions is currently lacking. In this study, liquid chromatography-linked tandem mass spectrometry of purified ebola and marburg virions was performed to identify associated cellular proteins. Host proteins involved in cell adhesion, cytoskeleton, cell signaling, intracellular trafficking, membrane organization, and chaperones were identified. Significant overlap exists between this data set and proteomic studies of disparate viruses, including HIV-1 and influenza A, generated in multiple cell types. However, the great majority of proteins identified here have not been previously described to be incorporated within filovirus particles. Host proteins identified by liquid chromatography-linked tandem mass spectrometry could lack biological relevance because they represent protein contaminants in the virus preparation, or because they are incorporated within virions by chance. These issues were addressed using siRNA library-mediated gene knockdown (targeting each identified virion-associated host protein), followed by filovirus infection. Knockdown of several host proteins (e.g. HSPA5 and RPL18) significantly interfered with ebolavirus and marburgvirus infection, suggesting specific and relevant virion incorporation. Notably, select siRNAs inhibited ebolavirus, but enhanced marburgvirus infection, suggesting important differences between the two viruses. The proteomic analysis presented here contributes to a greater understanding of filovirus biology and potentially identifies host factors that can be targeted for antiviral drug development. JF - Molecular and Cellular Proteomics AU - Spurgers, Kevin B AU - Alefantis, Tim AU - Peyser, Brian D AU - Ruthel, Gordon T AU - Bergeron, Alison A AU - Costantino, Julie A AU - Enterlein, Sven AU - Kota, Krishna P AU - Boltz, RCDutch AU - Aman, MJavad AU - DelVecchio, Vito G AU - Bavari, Sina AD - From the The United States Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Fort Detrick, Frederick, MD 21702, Vital Probes, Inc Y1 - 2010 PY - 2010 DA - 2010 SP - 2690 EP - 2703 PB - American Society for Biochemistry and Molecular Biology, 9650 Rockville Pike Bethesda MD 20814-3996 USA VL - 9 IS - 12 SN - 1535-9476, 1535-9476 KW - Biochemistry Abstracts 2: Nucleic Acids; Biotechnology and Bioengineering Abstracts KW - Virions KW - Intracellular signalling KW - Data processing KW - GRP78 protein KW - Influenza A KW - Drug development KW - Infection KW - Mass spectroscopy KW - Cell adhesion KW - Cytoskeleton KW - siRNA KW - Filovirus KW - Human immunodeficiency virus 1 KW - membrane trafficking KW - Protein composition KW - RNA-mediated interference KW - Chaperones KW - proteomics KW - Contaminants KW - N 14830:RNA KW - W 30960:Bioinformatics & Computer Applications UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/864951181?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Molecular+and+Cellular+Proteomics&rft.atitle=Identification+of+Essential+Filovirion-associated+Host+Factors+by+Serial+Proteomic+Analysis+and+RNAi+Screen&rft.au=Spurgers%2C+Kevin+B%3BAlefantis%2C+Tim%3BPeyser%2C+Brian+D%3BRuthel%2C+Gordon+T%3BBergeron%2C+Alison+A%3BCostantino%2C+Julie+A%3BEnterlein%2C+Sven%3BKota%2C+Krishna+P%3BBoltz%2C+RCDutch%3BAman%2C+MJavad%3BDelVecchio%2C+Vito+G%3BBavari%2C+Sina&rft.aulast=Spurgers&rft.aufirst=Kevin&rft.date=2010-01-01&rft.volume=9&rft.issue=12&rft.spage=2690&rft.isbn=&rft.btitle=&rft.title=Molecular+and+Cellular+Proteomics&rft.issn=15359476&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-05-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Virions; Intracellular signalling; Data processing; Influenza A; GRP78 protein; Drug development; Infection; Mass spectroscopy; Cell adhesion; Cytoskeleton; siRNA; Protein composition; membrane trafficking; RNA-mediated interference; Chaperones; proteomics; Contaminants; Filovirus; Human immunodeficiency virus 1 ER - TY - JOUR T1 - Modified region growing for stereo of slant and textureless surfaces AN - 864947920; 2011-040369 JF - Lecture Notes in Computer Science AU - Rohith, M V AU - Somanath, Gowri AU - Kambhamettu, Chandra AU - Geiger, Cathleen A AU - Finnegan, David AU - Bebis, George AU - Boyle, Richard AU - Koracin, Darko AU - Parvin, Bharam Y1 - 2010 PY - 2010 DA - 2010 SP - 666 EP - 677 PB - Springer-Verlag, Berlin VL - 6453 IS - Part 1 SN - 0302-9743, 0302-9743 KW - land cover KW - snow cover KW - cartography KW - data processing KW - ice cover KW - pixels KW - terrains KW - ice KW - snow KW - digital simulation KW - geomorphology KW - algorithms KW - landscapes KW - 23:Geomorphology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/864947920?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Lecture+Notes+in+Computer+Science&rft.atitle=Modified+region+growing+for+stereo+of+slant+and+textureless+surfaces&rft.au=Rohith%2C+M+V%3BSomanath%2C+Gowri%3BKambhamettu%2C+Chandra%3BGeiger%2C+Cathleen+A%3BFinnegan%2C+David%3BBebis%2C+George%3BBoyle%2C+Richard%3BKoracin%2C+Darko%3BParvin%2C+Bharam&rft.aulast=Rohith&rft.aufirst=M&rft.date=2010-01-01&rft.volume=6453&rft.issue=Part+1&rft.spage=666&rft.isbn=&rft.btitle=&rft.title=Lecture+Notes+in+Computer+Science&rft.issn=03029743&rft_id=info:doi/ L2 - http://www.springerlink.com/content/0302-9743/ LA - English DB - GeoRef N1 - Conference title - Sixth international symposium on Visual computing N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Number of references - 15 N1 - Document feature - illus. incl. 3 tables N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - algorithms; cartography; data processing; digital simulation; geomorphology; ice; ice cover; land cover; landscapes; pixels; snow; snow cover; terrains ER - TY - JOUR T1 - Influences of the ocean surface mixed layer and thermohaline stratification on Arctic sea ice in the central Canada Basin AN - 864943457; 2011-039457 AB - Variations in the Arctic central Canada Basin mixed layer properties are documented based on a subset of nearly 6500 temperature and salinity profiles acquired by Ice-Tethered Profilers during the period summer 2004 to summer 2009 and analyzed in conjunction with sea ice observations from ice mass balance buoys and atmosphere-ocean heat flux estimates. The July-August mean mixed layer depth based on the Ice-Tethered Profiler data averaged 16 m (an overestimate due to the Ice-Tethered Profiler sampling characteristics and present analysis procedures), while the average winter mixed layer depth was only 24 m, with individual observations rarely exceeding 40 m. Guidance interpreting the observations is provided by a 1-D ocean mixed layer model. The analysis focuses attention on the very strong density stratification at the base of the mixed layer in the Canada Basin that greatly impedes surface layer deepening and thus limits the flux of deep ocean heat to the surface that could influence sea ice growth/decay. The observations additionally suggest that efficient lateral mixed layer restratification processes are active in the Arctic, also impeding mixed layer deepening. JF - Journal of Geophysical Research AU - Toole, J M AU - Timmermans, M L AU - Perovich, Donald K AU - Krishfield, R A AU - Proshutinsky, A AU - Richter-Menge, Jacqueline A Y1 - 2010 PY - 2010 DA - 2010 EP - Citation C10018 PB - American Geophysical Union, Washington, DC VL - 115 IS - C10 SN - 0148-0227, 0148-0227 KW - ocean circulation KW - one-dimensional models KW - sea ice KW - ice cover KW - salinity KW - temperature KW - Canada Basin KW - thermohaline circulation KW - mixing KW - mass balance KW - ice KW - Arctic Ocean KW - bathymetry KW - 07:Oceanography UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/864943457?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Geophysical+Research&rft.atitle=Influences+of+the+ocean+surface+mixed+layer+and+thermohaline+stratification+on+Arctic+sea+ice+in+the+central+Canada+Basin&rft.au=Toole%2C+J+M%3BTimmermans%2C+M+L%3BPerovich%2C+Donald+K%3BKrishfield%2C+R+A%3BProshutinsky%2C+A%3BRichter-Menge%2C+Jacqueline+A&rft.aulast=Toole&rft.aufirst=J&rft.date=2010-01-01&rft.volume=115&rft.issue=C10&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Journal+of+Geophysical+Research&rft.issn=01480227&rft_id=info:doi/10.1029%2F2009JC005660 L2 - http://www.agu.org/journals/jgr/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by, and/or abstract, Copyright, American Geophysical Union, Washington, DC, United States N1 - Date revised - 2011-01-01 N1 - Number of references - 38 N1 - PubXState - DC N1 - Document feature - illus. incl. 2 tables N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - Arctic Ocean; bathymetry; Canada Basin; ice; ice cover; mass balance; mixing; ocean circulation; one-dimensional models; salinity; sea ice; temperature; thermohaline circulation DO - http://dx.doi.org/10.1029/2009JC005660 ER - TY - JOUR T1 - Effect of shear rupture on aggregate scale formation in sea ice AN - 864943401; 2011-039442 AB - A discrete element model is used to study shear rupture of sea ice under convergent wind stresses. The model includes compressive, tensile, and shear rupture of viscous elastic joints connecting floes that move under the action of the wind stresses. The adopted shear rupture is governed by Coulomb's criterion. The ice pack is a 400 km long square domain consisting of 4 km size floes. In the standard case with tensile strength 10 times smaller than the compressive strength, under uniaxial compression the failure regime is mainly shear rupture with the most probable scenario corresponding to that with the minimum failure work. The orientation of cracks delineating formed aggregates is bimodal with the peaks around the angles given by the wing crack theory determining diamond-shaped blocks. The ice block (floe aggregate) size decreases as the wind stress gradient increases since the elastic strain energy grows faster leading to a higher speed of crack propagation. As the tensile strength grows, shear rupture becomes harder to attain and compressive failure becomes equally important leading to elongation of blocks perpendicular to the compression direction and the blocks grow larger. In the standard case, as the wind stress confinement ratio increases the failure mode changes at a confinement ratio within 0.2-0.4, which corresponds to the analytical critical confinement ratio of 0.32. Below this value, the cracks are bimodal delineating diamond shape aggregates, while above this value failure becomes isotropic and is determined by small-scale stress anomalies due to irregularities in floe shape. JF - Journal of Geophysical Research AU - Wilchinsky, Alexander V AU - Feltham, Daniel L AU - Hopkins, Mark A Y1 - 2010 PY - 2010 DA - 2010 EP - Citation C10002 PB - American Geophysical Union, Washington, DC VL - 115 IS - C10 SN - 0148-0227, 0148-0227 KW - general circulation models KW - discrete element analysis KW - Southern Ocean KW - polar regions KW - ice pack KW - elasticity KW - shear stress KW - sea ice KW - stress KW - ice mechanics KW - deformation KW - ice floes KW - uniaxial tests KW - rupture KW - physical properties KW - cracks KW - viscosity KW - ice KW - Arctic Ocean KW - winds KW - faults KW - 07:Oceanography UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/864943401?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Geophysical+Research&rft.atitle=Effect+of+shear+rupture+on+aggregate+scale+formation+in+sea+ice&rft.au=Wilchinsky%2C+Alexander+V%3BFeltham%2C+Daniel+L%3BHopkins%2C+Mark+A&rft.aulast=Wilchinsky&rft.aufirst=Alexander&rft.date=2010-01-01&rft.volume=115&rft.issue=C10&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Journal+of+Geophysical+Research&rft.issn=01480227&rft_id=info:doi/10.1029%2F2009JC006043 L2 - http://www.agu.org/journals/jgr/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by, and/or abstract, Copyright, American Geophysical Union, Washington, DC, United States N1 - Date revised - 2011-01-01 N1 - Number of references - 29 N1 - PubXState - DC N1 - Document feature - illus. incl. 1 table N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - Arctic Ocean; cracks; deformation; discrete element analysis; elasticity; faults; general circulation models; ice; ice floes; ice mechanics; ice pack; physical properties; polar regions; rupture; sea ice; shear stress; Southern Ocean; stress; uniaxial tests; viscosity; winds DO - http://dx.doi.org/10.1029/2009JC006043 ER - TY - JOUR T1 - Porosity of micrometeorites measured by tomography AN - 859728174; 2011-030790 JF - Abstracts of Papers Submitted to the Lunar and Planetary Science Conference AU - Taylor, Susan AU - Jones, K W AU - Hornig, C AU - Herzog, G F AU - Anonymous Y1 - 2010 PY - 2010 DA - 2010 EP - Abstract 1909 PB - Lunar and Planetary Science Conference, Houston, TX VL - 41 KW - vesicular texture KW - tomography KW - atmospheric entry KW - textures KW - porosity KW - measurement KW - spatial distribution KW - micrometeorites KW - meteorites KW - physical properties KW - melting KW - porphyritic texture KW - volume KW - relict materials KW - heating KW - 05B:Petrology of meteorites and tektites UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/859728174?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Abstracts+of+Papers+Submitted+to+the+Lunar+and+Planetary+Science+Conference&rft.atitle=Porosity+of+micrometeorites+measured+by+tomography&rft.au=Taylor%2C+Susan%3BJones%2C+K+W%3BHornig%2C+C%3BHerzog%2C+G+F%3BAnonymous&rft.aulast=Taylor&rft.aufirst=Susan&rft.date=2010-01-01&rft.volume=41&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Abstracts+of+Papers+Submitted+to+the+Lunar+and+Planetary+Science+Conference&rft.issn=&rft_id=info:doi/ L2 - http://www.lpi.usra.edu/meetings/lpsc2010/pdf/1909.pdf LA - English DB - GeoRef N1 - Conference title - Forty-first lunar and planetary science conference N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Number of references - 5 N1 - PubXState - TX N1 - Document feature - illus. incl. 1 table N1 - SuppNotes - Accessed on Sept. 24, 2010 N1 - Last updated - 2012-06-07 N1 - CODEN - #02179 N1 - SubjectsTermNotLitGenreText - atmospheric entry; heating; measurement; melting; meteorites; micrometeorites; physical properties; porosity; porphyritic texture; relict materials; spatial distribution; textures; tomography; vesicular texture; volume ER - TY - JOUR T1 - A CAI micrometeorite AN - 859728069; 2011-030791 JF - Abstracts of Papers Submitted to the Lunar and Planetary Science Conference AU - Taylor, Susan AU - Delaney, J S AU - Herzog, G F AU - Anonymous Y1 - 2010 PY - 2010 DA - 2010 EP - Abstract 1205 PB - Lunar and Planetary Science Conference, Houston, TX VL - 41 KW - silicates KW - stony meteorites KW - calcium-aluminum inclusions KW - perovskite KW - olivine group KW - CV chondrites KW - electron probe data KW - meteorites KW - pyroxene group KW - mineral composition KW - clinopyroxene KW - aluminum KW - inclusions KW - orthosilicates KW - oxides KW - fassaite KW - chondrites KW - chain silicates KW - spinel KW - carbonaceous chondrites KW - forsterite KW - nesosilicates KW - micrometeorites KW - titanium KW - metals KW - 05B:Petrology of meteorites and tektites UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/859728069?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Abstracts+of+Papers+Submitted+to+the+Lunar+and+Planetary+Science+Conference&rft.atitle=A+CAI+micrometeorite&rft.au=Taylor%2C+Susan%3BDelaney%2C+J+S%3BHerzog%2C+G+F%3BAnonymous&rft.aulast=Taylor&rft.aufirst=Susan&rft.date=2010-01-01&rft.volume=41&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Abstracts+of+Papers+Submitted+to+the+Lunar+and+Planetary+Science+Conference&rft.issn=&rft_id=info:doi/ L2 - http://www.lpi.usra.edu/meetings/lpsc2010/pdf/1205.pdf LA - English DB - GeoRef N1 - Conference title - Forty-first lunar and planetary science conference N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Number of references - 11 N1 - PubXState - TX N1 - Document feature - illus. incl. 1 table N1 - SuppNotes - Accessed on Sept. 24, 2010 N1 - Last updated - 2012-06-07 N1 - CODEN - #02179 N1 - SubjectsTermNotLitGenreText - aluminum; calcium-aluminum inclusions; carbonaceous chondrites; chain silicates; chondrites; clinopyroxene; CV chondrites; electron probe data; fassaite; forsterite; inclusions; metals; meteorites; micrometeorites; mineral composition; nesosilicates; olivine group; orthosilicates; oxides; perovskite; pyroxene group; silicates; spinel; stony meteorites; titanium ER - TY - JOUR T1 - Effect of hypohydration and altitude exposure on aerobic exercise performance and acute mountain sickness AN - 856762378; 14048230 AB - Hypoxia often causes body water deficits (hypohydration, HYPO); however, the effects of HYPO on aerobic exercise performance and prevalence of acute mountain sickness (AMS) at high altitude (ALT) have not been reported. We hypothesized that 1) HYPO and ALT would each degrade aerobic performance relative to sea level (SL)-euhydrated (EUH) conditions, and combining HYPO and ALT would further degrade performance more than one stressor alone; and 2) HYPO would increase the prevalence and severity of AMS symptoms. Seven lowlander men (25 plus or minus 7 yr old; 82 plus or minus 11 kg; mean plus or minus SD) completed four separate experimental trials. Trials were 1) SL-EUH, 2) SL-HYPO, 3) ALT-EUH, and 4) ALT-HYPO. In HYPO, subjects were dehydrated by 4% of body mass. Subjects maintained hydration status overnight and the following morning entered a hypobaric chamber (at SL or 3,048 m, 27 degree C) where they completed 30 min of submaximal exercise immediately followed by a 30-min performance time trial (TT). AMS was measured with the Environmental Symptoms Questionnaire-Cerebral Score (AMS-C) and the Lake Louise Scoring System (LLS). The percent change in TT performance, relative to SL-EUH, was -19 plus or minus 12% (334 plus or minus 64 to 278 plus or minus 87 kJ), -11 plus or minus 10% (334 plus or minus 64 to 293 plus or minus 33 kJ), and -34 plus or minus 22% (334 plus or minus 64 to 227 plus or minus 95 kJ), for SL-HYPO, ALT-EUH, and ALT-HYPO, respectively. AMS symptom prevalence was 2/7 subjects at ALT-EUH for AMS-C and LLS and 5/7 and 4/7 at ALT-HYPO for AMS-C and LLS, respectively. The AMS-C symptom severity score (AMS-C score) tended to increase from ALT-EUH to ALT-HYPO but was not significant (P = 0.07). In conclusion, hypohydration at 3,048 m 1) degrades aerobic performance in an additive manner with that induced by ALT; and 2) did not appear to increase the prevalence/severity of AMS symptoms. JF - Journal of Applied Physiology AU - Castellani, John W AU - Muza, Stephen R AU - Cheuvront, Samuel N AU - Sils, Ingrid V AU - Fulco, Charles S AU - Kenefick, Robert W AU - Beidleman, Beth A AU - Sawka, Michael N AD - Thermal and Mountain Medicine Division, U.S. Army Research Institute of Environmental Medicine, Natick, Massachusetts Y1 - 2010 PY - 2010 DA - 2010 SP - 1792 EP - 1800 PB - American Physiological Society, 9650 Rockville Pike Bethesda MD 20814-3991 USA VL - 109 IS - 6 SN - 1522-1601, 1522-1601 KW - Toxicology Abstracts; Physical Education Index; ASFA 2: Ocean Technology Policy & Non-Living Resources KW - Hydration KW - Measurement KW - Symptoms KW - Exercise physiology KW - Aerobics KW - Body mass KW - Body water KW - Illness KW - Water KW - Physical training KW - Mountains KW - Lakes KW - Altitude KW - Fluid replacement KW - Hypoxia KW - Performance KW - Dehydration KW - X 24490:Other KW - Q2 09167:Tides, surges and sea level KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/856762378?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Physiology&rft.atitle=Effect+of+hypohydration+and+altitude+exposure+on+aerobic+exercise+performance+and+acute+mountain+sickness&rft.au=Castellani%2C+John+W%3BMuza%2C+Stephen+R%3BCheuvront%2C+Samuel+N%3BSils%2C+Ingrid+V%3BFulco%2C+Charles+S%3BKenefick%2C+Robert+W%3BBeidleman%2C+Beth+A%3BSawka%2C+Michael+N&rft.aulast=Castellani&rft.aufirst=John&rft.date=2010-01-01&rft.volume=109&rft.issue=6&rft.spage=1792&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Physiology&rft.issn=15221601&rft_id=info:doi/ LA - English DB - Physical Education Index; ProQuest Environmental Science Collection N1 - Date revised - 2011-03-01 N1 - Last updated - 2014-05-02 N1 - SubjectsTermNotLitGenreText - Hydration; Symptoms; Hypoxia; Measurement; Exercise physiology; Altitude; Fluid replacement; Aerobics; Performance; Illness; Water; Dehydration; Mountains; Lakes; Body mass; Body water; Physical training ER - TY - JOUR T1 - Unique thermosyphon roadway test site spanning 11 years AN - 855197351; 2011-026073 JF - Canadian Geotechnical Conference = Conference Canadienne de Geotechnique AU - Wagner, Anna M AU - Zarling, John P AU - Yarmak, Edward, Jr AU - Long, Erwin L AU - Kwok, Charles AU - Armstrong, Robert AU - Henderson, Jim Y1 - 2010 PY - 2010 DA - 2010 SP - 1770 EP - 1776 PB - Canadian Geotechnical Conference, Vancouver, BC VL - 63 SN - 0821-3763, 0821-3763 KW - United States KW - soil mechanics KW - Fairbanks Alaska KW - embankments KW - permafrost KW - temperature KW - cold weather construction KW - Alaska KW - slope stability KW - frozen ground KW - construction KW - roads KW - 30:Engineering geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/855197351?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Canadian+Geotechnical+Conference+%3D+Conference+Canadienne+de+Geotechnique&rft.atitle=Unique+thermosyphon+roadway+test+site+spanning+11+years&rft.au=Wagner%2C+Anna+M%3BZarling%2C+John+P%3BYarmak%2C+Edward%2C+Jr%3BLong%2C+Erwin+L%3BKwok%2C+Charles%3BArmstrong%2C+Robert%3BHenderson%2C+Jim&rft.aulast=Wagner&rft.aufirst=Anna&rft.date=2010-01-01&rft.volume=63&rft.issue=&rft.spage=1770&rft.isbn=&rft.btitle=&rft.title=Canadian+Geotechnical+Conference+%3D+Conference+Canadienne+de+Geotechnique&rft.issn=08213763&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Sixty-third Canadian geotechnical conference and 6th Canadian permafrost conference N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Number of references - 5 N1 - PubXState - BC N1 - Document feature - illus. incl. sketch map N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - Alaska; cold weather construction; construction; embankments; Fairbanks Alaska; frozen ground; permafrost; roads; slope stability; soil mechanics; temperature; United States ER - TY - JOUR T1 - The history and future of the permafrost tunnel near Fox, Alaska AN - 855197169; 2011-025998 JF - Canadian Geotechnical Conference = Conference Canadienne de Geotechnique AU - Cysewski, Margaret AU - Bjella, Kevin AU - Sturm, Matthew AU - Kwok, Charles AU - Armstrong, Robert AU - Henderson, Jim Y1 - 2010 PY - 2010 DA - 2010 SP - 1222 EP - 1227 PB - Canadian Geotechnical Conference, Vancouver, BC VL - 63 SN - 0821-3763, 0821-3763 KW - United States KW - civil engineering KW - soil mechanics KW - permafrost KW - engineering properties KW - mechanical properties KW - excavations KW - cold weather construction KW - Fox Alaska KW - tunnels KW - Fairbanks Quadrangle KW - Alaska KW - infrastructure KW - frozen ground KW - construction KW - 30:Engineering geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/855197169?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Canadian+Geotechnical+Conference+%3D+Conference+Canadienne+de+Geotechnique&rft.atitle=The+history+and+future+of+the+permafrost+tunnel+near+Fox%2C+Alaska&rft.au=Cysewski%2C+Margaret%3BBjella%2C+Kevin%3BSturm%2C+Matthew%3BKwok%2C+Charles%3BArmstrong%2C+Robert%3BHenderson%2C+Jim&rft.aulast=Cysewski&rft.aufirst=Margaret&rft.date=2010-01-01&rft.volume=63&rft.issue=&rft.spage=1222&rft.isbn=&rft.btitle=&rft.title=Canadian+Geotechnical+Conference+%3D+Conference+Canadienne+de+Geotechnique&rft.issn=08213763&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Sixty-third Canadian geotechnical conference and 6th Canadian permafrost conference N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Number of references - 27 N1 - PubXState - BC N1 - Document feature - illus. incl. sketch map N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - Alaska; civil engineering; cold weather construction; construction; engineering properties; excavations; Fairbanks Quadrangle; Fox Alaska; frozen ground; infrastructure; mechanical properties; permafrost; soil mechanics; tunnels; United States ER - TY - JOUR T1 - Air-ducted hangar foundations at Thule, Greenland AN - 855196383; 2011-025962 JF - Canadian Geotechnical Conference = Conference Canadienne de Geotechnique AU - Bjella, Kevin AU - Kwok, Charles AU - Armstrong, Robert AU - Henderson, Jim Y1 - 2010 PY - 2010 DA - 2010 SP - 970 EP - 977 PB - Canadian Geotechnical Conference, Vancouver, BC VL - 63 SN - 0821-3763, 0821-3763 KW - soil mechanics KW - permafrost KW - clastic sediments KW - Arctic region KW - Thule Air Base KW - till KW - glaciofluvial environment KW - cold weather construction KW - Greenland KW - foundations KW - glacial environment KW - sediments KW - military facilities KW - frozen ground KW - fluvial environment KW - construction KW - design KW - 30:Engineering geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/855196383?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Canadian+Geotechnical+Conference+%3D+Conference+Canadienne+de+Geotechnique&rft.atitle=Air-ducted+hangar+foundations+at+Thule%2C+Greenland&rft.au=Bjella%2C+Kevin%3BKwok%2C+Charles%3BArmstrong%2C+Robert%3BHenderson%2C+Jim&rft.aulast=Bjella&rft.aufirst=Kevin&rft.date=2010-01-01&rft.volume=63&rft.issue=&rft.spage=970&rft.isbn=&rft.btitle=&rft.title=Canadian+Geotechnical+Conference+%3D+Conference+Canadienne+de+Geotechnique&rft.issn=08213763&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Sixty-third Canadian geotechnical conference and 6th Canadian permafrost conference N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Number of references - 12 N1 - PubXState - BC N1 - Document feature - illus. incl. sketch map N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - Arctic region; clastic sediments; cold weather construction; construction; design; fluvial environment; foundations; frozen ground; glacial environment; glaciofluvial environment; Greenland; military facilities; permafrost; sediments; soil mechanics; Thule Air Base; till ER - TY - JOUR T1 - Particle entrainment by non-uniform eolian flow AN - 849008356; 2011-013894 JF - Proceedings - Biennial International Conference on Engineering, Construction, and Operations in Challenging Environments AU - Haehnel, Robert B AU - Dade, Brian W AU - Song, Gangbing Y1 - 2010 PY - 2010 DA - 2010 SP - 158 EP - 165 PB - American Society of Civil Engineers (ASCE), Aerospace Division, Reston, VA VL - 12 KW - soils KW - experimental studies KW - sediment transport KW - erosion KW - shear stress KW - turbulence KW - laboratory studies KW - transport KW - turbidity KW - wind transport KW - soil erosion KW - kinetics KW - 25:Soils UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/849008356?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Proceedings+-+Biennial+International+Conference+on+Engineering%2C+Construction%2C+and+Operations+in+Challenging+Environments&rft.atitle=Particle+entrainment+by+non-uniform+eolian+flow&rft.au=Haehnel%2C+Robert+B%3BDade%2C+Brian+W%3BSong%2C+Gangbing&rft.aulast=Haehnel&rft.aufirst=Robert&rft.date=2010-01-01&rft.volume=12&rft.issue=&rft.spage=158&rft.isbn=&rft.btitle=&rft.title=Proceedings+-+Biennial+International+Conference+on+Engineering%2C+Construction%2C+and+Operations+in+Challenging+Environments&rft.issn=&rft_id=info:doi/ L2 - http://content.asce.org/conferences/earth2008/welcome.html LA - English DB - GeoRef N1 - Conference title - Earth and space 2010 N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Number of references - 11 N1 - PubXState - VA N1 - Document feature - illus. incl. 1 table N1 - Last updated - 2012-06-07 N1 - CODEN - #06816 N1 - SubjectsTermNotLitGenreText - erosion; experimental studies; kinetics; laboratory studies; sediment transport; shear stress; soil erosion; soils; transport; turbidity; turbulence; wind transport ER - TY - JOUR T1 - Seasonality of spectral albedo and transmittance as observed in the Arctic Transpolar Drift in 2007 AN - 849008229; 2011-013889 AB - The first continuous and high temporal resolution record of spectral albedo and transmittance of snow and sea ice in the Arctic Ocean over an entire summer season is presented. Measurements were performed at a manned station on multiyear sea ice in the Transpolar Drift during the drift of the schooner Tara from April to September 2007. Concurrent autonomous measurements of ice mass balance and weekly observations of snow and sea-ice properties complement the data set. The seasonality of physical and biological processes of snow and sea ice is characterized, including quantification of melt onset (10 June), melt season duration, and freeze onset (15 August). Over one year, approximately two thirds of the transmitted energy reached the ocean during the 66-day-long melt season. During the second half of July, transmitted irradiance decreased by 90% and absorption in and directly under the ice increased, significantly affecting the vertical partitioning of irradiance. The spectral radiation time series suggests that high biomass abundance in or below the sea ice caused this decrease. Comparing the spectral data set with broadband albedo data measured at the same location shows that 90% of the temporal variability of broadband albedo can be explained by variability in spectral albedo integrated over the limited wavelength range. The combination of spectral radiation and ice mass balance measurements allows a comprehensive description, and quantification, of snow and sea-ice processes, even with minimal additional in situ observations, suggesting such data sets can be collected autonomously to provide insight into the physical and biological processes on sea ice. JF - Journal of Geophysical Research AU - Nicolaus, Marcel AU - Gerland, Sebastian AU - Hudson, Stephen R AU - Hanson, Susanne AU - Haapala, Jari AU - Perovich, Donald K Y1 - 2010 PY - 2010 DA - 2010 EP - C11011 PB - American Geophysical Union, Washington, DC VL - 115 IS - C11 SN - 0148-0227, 0148-0227 KW - albedo KW - snow cover KW - Arctic region KW - sea ice KW - ice cover KW - global change KW - freezing KW - energy balance KW - wavelength KW - spatial distribution KW - physical properties KW - melting KW - mass balance KW - ice KW - snow KW - solar radiation KW - climate effects KW - Arctic Ocean KW - seasonal variations KW - productivity KW - global warming KW - 07:Oceanography UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/849008229?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Geophysical+Research&rft.atitle=Seasonality+of+spectral+albedo+and+transmittance+as+observed+in+the+Arctic+Transpolar+Drift+in+2007&rft.au=Nicolaus%2C+Marcel%3BGerland%2C+Sebastian%3BHudson%2C+Stephen+R%3BHanson%2C+Susanne%3BHaapala%2C+Jari%3BPerovich%2C+Donald+K&rft.aulast=Nicolaus&rft.aufirst=Marcel&rft.date=2010-01-01&rft.volume=115&rft.issue=C11&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Journal+of+Geophysical+Research&rft.issn=01480227&rft_id=info:doi/10.1029%2F2009JC006074 L2 - http://www.agu.org/journals/jgr/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by, and/or abstract, Copyright, American Geophysical Union, Washington, DC, United States N1 - Date revised - 2011-01-01 N1 - Number of references - 68 N1 - PubXState - DC N1 - Document feature - illus. incl. 3 tables N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - albedo; Arctic Ocean; Arctic region; climate effects; energy balance; freezing; global change; global warming; ice; ice cover; mass balance; melting; physical properties; productivity; sea ice; seasonal variations; snow; snow cover; solar radiation; spatial distribution; wavelength DO - http://dx.doi.org/10.1029/2009JC006074 ER - TY - JOUR T1 - Lunar suitcase science; a lunar regolith characterization kit AN - 849008163; 2011-013895 JF - Proceedings - Biennial International Conference on Engineering, Construction, and Operations in Challenging Environments AU - Johnson, J B AU - Mungas, G S AU - Zacny, K AU - Albert, Donald G AU - Banerdt, B AU - Buehler, M AU - Elphic, R AU - Johnson, K AU - Lambert, J AU - Sturm, Matthew AU - Song, Gangbing Y1 - 2010 PY - 2010 DA - 2010 SP - 1211 EP - 1234 PB - American Society of Civil Engineers (ASCE), Aerospace Division, Reston, VA VL - 12 KW - seismic profiles KW - Moon KW - geophysical methods KW - information management KW - temperature KW - seismic methods KW - data management KW - heat flow KW - geophysical profiles KW - regolith KW - instruments KW - design KW - lunar soils KW - 04:Extraterrestrial geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/849008163?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Proceedings+-+Biennial+International+Conference+on+Engineering%2C+Construction%2C+and+Operations+in+Challenging+Environments&rft.atitle=Lunar+suitcase+science%3B+a+lunar+regolith+characterization+kit&rft.au=Johnson%2C+J+B%3BMungas%2C+G+S%3BZacny%2C+K%3BAlbert%2C+Donald+G%3BBanerdt%2C+B%3BBuehler%2C+M%3BElphic%2C+R%3BJohnson%2C+K%3BLambert%2C+J%3BSturm%2C+Matthew%3BSong%2C+Gangbing&rft.aulast=Johnson&rft.aufirst=J&rft.date=2010-01-01&rft.volume=12&rft.issue=&rft.spage=1211&rft.isbn=&rft.btitle=&rft.title=Proceedings+-+Biennial+International+Conference+on+Engineering%2C+Construction%2C+and+Operations+in+Challenging+Environments&rft.issn=&rft_id=info:doi/ L2 - http://content.asce.org/conferences/earth2008/welcome.html LA - English DB - GeoRef N1 - Conference title - Earth and space 2010 N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Number of references - 34 N1 - PubXState - VA N1 - Document feature - illus. incl. 1 table N1 - Last updated - 2012-06-07 N1 - CODEN - #06816 N1 - SubjectsTermNotLitGenreText - data management; design; geophysical methods; geophysical profiles; heat flow; information management; instruments; lunar soils; Moon; regolith; seismic methods; seismic profiles; temperature ER - TY - JOUR T1 - A particle-scale model to simulate soil/regolith erosion AN - 849007998; 2011-013893 JF - Proceedings - Biennial International Conference on Engineering, Construction, and Operations in Challenging Environments AU - Haehnel, Robert B AU - Kaempfer, Thomas U AU - Hopkins, Mark A AU - Song, Gangbing Y1 - 2010 PY - 2010 DA - 2010 SP - 1 EP - 12 PB - American Society of Civil Engineers (ASCE), Aerospace Division, Reston, VA VL - 12 KW - soils KW - discrete element analysis KW - experimental studies KW - erosion KW - wind erosion KW - turbulence KW - two-dimensional models KW - models KW - laboratory studies KW - transport KW - wind tunnels KW - turbidity KW - wind transport KW - soil erosion KW - regolith KW - 25:Soils UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/849007998?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Proceedings+-+Biennial+International+Conference+on+Engineering%2C+Construction%2C+and+Operations+in+Challenging+Environments&rft.atitle=A+particle-scale+model+to+simulate+soil%2Fregolith+erosion&rft.au=Haehnel%2C+Robert+B%3BKaempfer%2C+Thomas+U%3BHopkins%2C+Mark+A%3BSong%2C+Gangbing&rft.aulast=Haehnel&rft.aufirst=Robert&rft.date=2010-01-01&rft.volume=12&rft.issue=&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Proceedings+-+Biennial+International+Conference+on+Engineering%2C+Construction%2C+and+Operations+in+Challenging+Environments&rft.issn=&rft_id=info:doi/ L2 - http://content.asce.org/conferences/earth2008/welcome.html LA - English DB - GeoRef N1 - Conference title - Earth and space 2010 N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Number of references - 11 N1 - PubXState - VA N1 - Document feature - illus. incl. 2 tables N1 - Last updated - 2012-06-07 N1 - CODEN - #06816 N1 - SubjectsTermNotLitGenreText - discrete element analysis; erosion; experimental studies; laboratory studies; models; regolith; soil erosion; soils; transport; turbidity; turbulence; two-dimensional models; wind erosion; wind transport; wind tunnels ER - TY - JOUR T1 - Origin of differentiated cosmic spherules; insights from trace element geochemistry AN - 849004357; 2011-013328 JF - Abstracts of Papers Submitted to the Lunar and Planetary Science Conference AU - Cordier, C AU - Folco, L AU - Taylor, Susan AU - Anonymous Y1 - 2010 PY - 2010 DA - 2010 EP - Abstract 1132 PB - Lunar and Planetary Science Conference, Houston, TX VL - 41 KW - Transantarctic Mountains KW - volcanic rocks KW - stony meteorites KW - Martian meteorites KW - igneous rocks KW - mass spectra KW - fugacity KW - electron probe data KW - SNC Meteorites KW - meteorites KW - major elements KW - basalts KW - spectra KW - rare earths KW - trace elements KW - chemical ratios KW - spherules KW - parent bodies KW - differentiation KW - cosmic spherules KW - achondrites KW - overprinting KW - ICP mass spectra KW - micrometeorites KW - Antarctica KW - shergottite KW - metals KW - eucrite KW - 05B:Petrology of meteorites and tektites UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/849004357?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Abstracts+of+Papers+Submitted+to+the+Lunar+and+Planetary+Science+Conference&rft.atitle=Origin+of+differentiated+cosmic+spherules%3B+insights+from+trace+element+geochemistry&rft.au=Cordier%2C+C%3BFolco%2C+L%3BTaylor%2C+Susan%3BAnonymous&rft.aulast=Cordier&rft.aufirst=C&rft.date=2010-01-01&rft.volume=41&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Abstracts+of+Papers+Submitted+to+the+Lunar+and+Planetary+Science+Conference&rft.issn=&rft_id=info:doi/10.1016%2Fj.biologicals.2008.03.001 L2 - http://www.lpi.usra.edu/meetings/lpsc2010/pdf/1132.pdf LA - English DB - GeoRef N1 - Conference title - Forty-first lunar and planetary science conference N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Number of references - 16 N1 - PubXState - TX N1 - Document feature - illus. incl. 1 table N1 - SuppNotes - Accessed on Aug. 24, 2010 N1 - Last updated - 2012-06-07 N1 - CODEN - #02179 N1 - SubjectsTermNotLitGenreText - achondrites; Antarctica; basalts; chemical ratios; cosmic spherules; differentiation; electron probe data; eucrite; ICP mass spectra; igneous rocks; major elements; Martian meteorites; mass spectra; metals; meteorites; micrometeorites; overprinting; fugacity; parent bodies; rare earths; shergottite; SNC Meteorites; spectra; spherules; stony meteorites; trace elements; Transantarctic Mountains; volcanic rocks ER - TY - JOUR T1 - Transcriptional analysis of differential carbohydrate utilization by Clostridium acetobutylicum AN - 839676204; 13967818 AB - Transcriptional analysis was performed on Clostridium acetobutylicum with the goal of identifying sugar-specific mechanisms for the transcriptional regulation of transport and metabolism genes. DNA microarrays were used to determine transcript levels from total RNA isolated from cells grown on media containing eleven different carbohydrates, including two pentoses (xylose, arabinose), four hexoses (glucose, mannose, galactose, fructose), four disaccharides (sucrose, lactose, maltose, cellobiose) and one polysaccharide (starch). Sugar-specific induction of many transport and metabolism genes indicates that these processes are regulated at the transcriptional level and are subject to carbon catabolite repression. The results show that C. acetobutylicum utilizes symporters and ATP-binding cassette (ABC) transporters for the uptake of pentose sugars, while disaccharides and hexoses are primarily taken up by phosphotransferase system (PTS) transporters and a gluconate : H+ (GntP) transporter. The transcription of some transporter genes was induced by specific sugars, while others were induced by a subset of the sugars tested. Sugar-specific transport roles are suggested, based on expression comparisons, for various transporters of the PTS, the ABC superfamily and members of the major facilitator superfamily (MFS), including the GntP symporter family and the glycoside-pentoside-hexuronide (GPH)-cation symporter family. Additionally, updates to the C. acetobutylicum genome annotation are proposed, including the identification of genes likely to encode proteins involved in the metabolism of arabinose and xylose via the pentose phosphate pathway. JF - Microbiology AU - Servinsky, Matthew D AU - Kiel, James T AU - Dupuy, Nicole F AU - Sund, Christian J AD - U S Army Research Laboratory, 2800 Powder Mill Road, Adelphi, Maryland 20783, USA Y1 - 2010 PY - 2010 DA - 2010 SP - 3478 EP - 3491 PB - Society for General Microbiology, Marlborough House, Basingstoke Road Reading RG7 1AG UK VL - 156 SN - 1350-0872, 1350-0872 KW - Microbiology Abstracts B: Bacteriology KW - Galactose KW - Genomes KW - Xylose KW - cellobiose KW - Glucose KW - Hydrogen KW - Starch KW - Polysaccharides KW - DNA microarrays KW - Carbon KW - Sucrose KW - Carbohydrates KW - Maltose KW - Sugar KW - Lactose KW - Pentose phosphate pathway KW - ABC transporter KW - Mannose KW - Transcription KW - phosphotransferase KW - Disaccharides KW - Media (differential) KW - RNA KW - Hexose KW - Gene regulation KW - Fructose KW - Clostridium acetobutylicum KW - Arabinose KW - Catabolite repression KW - Metabolism KW - J 02320:Cell Biology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839676204?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Microbiology&rft.atitle=Transcriptional+analysis+of+differential+carbohydrate+utilization+by+Clostridium+acetobutylicum&rft.au=Servinsky%2C+Matthew+D%3BKiel%2C+James+T%3BDupuy%2C+Nicole+F%3BSund%2C+Christian+J&rft.aulast=Servinsky&rft.aufirst=Matthew&rft.date=2010-01-01&rft.volume=103&rft.issue=3&rft.spage=255&rft.isbn=&rft.btitle=&rft.title=Basic+%26+Clinical+Pharmacology+%26+Toxicology&rft.issn=17427835&rft_id=info:doi/10.1111%2Fj.1742-7843.2008.00255.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-01 N1 - Last updated - 2013-09-09 N1 - SubjectsTermNotLitGenreText - Genomes; Galactose; Xylose; cellobiose; Glucose; Hydrogen; Polysaccharides; Starch; DNA microarrays; Carbon; Sucrose; Carbohydrates; Maltose; Sugar; Lactose; Pentose phosphate pathway; ABC transporter; Mannose; Transcription; phosphotransferase; Disaccharides; Media (differential); Hexose; RNA; Gene regulation; Fructose; Catabolite repression; Arabinose; Metabolism; Clostridium acetobutylicum ER - TY - JOUR T1 - Cross Modal Congruency Benefits for Combined Tactile and Visual Signaling AN - 839573469; 201102885 AB - This series of experiments tested the assimilation and efficacy of tactile messages that were created based on five common military arm and hand signals. We compared the response times and accuracy rates for these tactile representations against responses to equivalent visual representations of the same messages. Experimentally, such messages were displayed in either tactile or visual forms alone, or using both modalities in combination. There was a performance benefit for concurrent message presentations, which showed superior response times and improved accuracy rates when compared with individual presentations in either modality alone. Such improvement was due largely to a reduction in premotor response time. These improvements occurred equally in military and nonmilitary samples. Potential reasons for this multimodal facilitation are discussed. On a practical level, these results confirm the utility of tactile messaging to augment visual messaging, especially in challenging and stressful environments where visual messaging is not feasible or effective. Adapted from the source document. JF - American Journal of Psychology AU - Merlo, James L AU - Duley, Aaron R AU - Hancock, Peter A AD - United States Military Academy, West Point Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 413 EP - 424 PB - University of Illinois Press, Champaign VL - 123 IS - 4 SN - 0002-9556, 0002-9556 KW - Stressful environment KW - Reaction times KW - Assimilation KW - Facilitation KW - Visual representation KW - Accuracy KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839573469?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Psychology&rft.atitle=Cross+Modal+Congruency+Benefits+for+Combined+Tactile+and+Visual+Signaling&rft.au=Merlo%2C+James+L%3BDuley%2C+Aaron+R%3BHancock%2C+Peter+A&rft.aulast=Merlo&rft.aufirst=James&rft.date=2010-01-01&rft.volume=34&rft.issue=1&rft.spage=7&rft.isbn=&rft.btitle=&rft.title=Ecological+Engineering&rft.issn=09258574&rft_id=info:doi/10.1016%2Fj.ecoleng.2008.05.004 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2011-01-10 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPCAA N1 - SubjectsTermNotLitGenreText - Reaction times; Accuracy; Assimilation; Visual representation; Stressful environment; Facilitation ER - TY - JOUR T1 - Countering Irregular Threats: The Army Special Operations Contribution AN - 837451381; 2010-11213 AB - The joint Services and interagency communities predict a future of persistent conflict consisting of irregular or hybrid threats within an irregular warfare (IW) environment requiring forces to operate across the spectrum of military operations. The US Army Special Operations Command (USASOC) embraces the joint, US Special Operations Command (USSOCOM) and Army vision of this future threat and, as the designated Army component to USSOCOM, is responsible for recruiting, educating, organizing, training, manning, equipping, and deploying Army special operations forces (ARSOF) to accomplish special operations missions in support of combatant commanders and chiefs of mission. Tables, Figures. Adapted from the source document. JF - Joint Force Quarterly AU - Mulholland, John F, Jr AD - United States Army Special Operations Command Y1 - 2010///0, PY - 2010 DA - 0, 2010 SP - 71 EP - 75 PB - Institute for National Strategic Studies, National Defense University, Washington DC VL - 1st Quarter IS - 56 SN - 1070-0692, 1070-0692 KW - Military and defense policy - Military planning, strategy, and operations KW - International relations - War KW - Politics - Political dissent and internal conflict KW - Special forces KW - Military operations KW - United States Army KW - Conflict KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/837451381?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Joint+Force+Quarterly&rft.atitle=Countering+Irregular+Threats%3A+The+Army+Special+Operations+Contribution&rft.au=Mulholland%2C+John+F%2C+Jr&rft.aulast=Mulholland&rft.aufirst=John&rft.date=2010-01-01&rft.volume=1st+Quarter&rft.issue=56&rft.spage=71&rft.isbn=&rft.btitle=&rft.title=Joint+Force+Quarterly&rft.issn=10700692&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2011-01-10 N1 - SuppNotes - http://www.ndu.edu/press/lib/images/jfq-56/9.pdf N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - United States Army; Special forces; Military operations; Conflict ER - TY - JOUR T1 - Vice Chairmen of the Joint Chiefs of Staff and Leadership of the Joint Requirements Oversight Council AN - 837451002; 2010-11225 AB - Military leaders at many levels have used the advice and processes associated with strategic planning councils in various ways to position their organizations to respond to the demands of current situations while simultaneously transforming to meet future challenges. This article broadly identifies how the last seven Vice Chairmen of the Joint Chiefs of Staff led the Joint Requirements Oversight Council (JROC), the Nation's most senior joint military advice council, to provide recommendations to the Chairman of the Joint Chiefs of Staff (CJCS) to help enable him to meet his resource-focused responsibilities. Tables, Figures. Adapted from the source document. JF - Joint Force Quarterly AU - Meinhart, Richard M AD - United States Army War Coll Y1 - 2010///0, PY - 2010 DA - 0, 2010 SP - 144 EP - 151 PB - Institute for National Strategic Studies, National Defense University, Washington DC VL - 1st Quarter IS - 56 SN - 1070-0692, 1070-0692 KW - Military and defense policy - Military planning, strategy, and operations KW - Law and ethics - Criminal law KW - Government - Internal security KW - Politics - Politics and policy-making KW - Government - Public officials KW - Culture and religion - Intellectual life KW - United States KW - Military planning KW - Presidents KW - Decision-making KW - Leadership KW - Surveillance KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/837451002?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Joint+Force+Quarterly&rft.atitle=Vice+Chairmen+of+the+Joint+Chiefs+of+Staff+and+Leadership+of+the+Joint+Requirements+Oversight+Council&rft.au=Meinhart%2C+Richard+M&rft.aulast=Meinhart&rft.aufirst=Richard&rft.date=2010-01-01&rft.volume=1st+Quarter&rft.issue=56&rft.spage=144&rft.isbn=&rft.btitle=&rft.title=Joint+Force+Quarterly&rft.issn=10700692&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2011-01-10 N1 - SuppNotes - http://www.ndu.edu/press/lib/images/jfq-56/24.pdf N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - United States; Military planning; Surveillance; Leadership; Presidents; Decision-making ER - TY - JOUR T1 - The Struggle against Global Insurgency AN - 837450249; 2010-11223 AB - Since 9/11, it has become commonplace for scholars, politicians, and military thinkers to refer to current US military and diplomatic actions as being part of a larger "war on terror." This is an extremely imprecise characterization of the current conflict -- What the US and, in fact, the world are facing is more properly dubbed a global insurgent movement that emanates from al Qaeda at the international level and that slowly seeps into legitimate (and illegitimate) national secessionist movements around the world. Tables, Figures. Adapted from the source document. JF - Joint Force Quarterly AU - Cox, Daniel G AD - United States Army School Advanced Military Studies, Fort Leavenworth, Kansas. Y1 - 2010///0, PY - 2010 DA - 0, 2010 SP - 135 EP - 139 PB - Institute for National Strategic Studies, National Defense University, Washington DC VL - 1st Quarter IS - 56 SN - 1070-0692, 1070-0692 KW - Military and defense policy - National defense KW - International relations - International peace and security KW - International relations - International relations KW - Politics - Political ideologies and movements KW - Social conditions and policy - Social movements KW - Secession KW - United States KW - Counterterrorism KW - Geopolitics KW - Social movements KW - Counterinsurgency KW - Al Qaeda KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/837450249?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Joint+Force+Quarterly&rft.atitle=The+Struggle+against+Global+Insurgency&rft.au=Cox%2C+Daniel+G&rft.aulast=Cox&rft.aufirst=Daniel&rft.date=2010-01-01&rft.volume=1st+Quarter&rft.issue=56&rft.spage=135&rft.isbn=&rft.btitle=&rft.title=Joint+Force+Quarterly&rft.issn=10700692&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2011-01-10 N1 - SuppNotes - http://www.ndu.edu/press/lib/images/jfq-56/22.pdf N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Counterinsurgency; Counterterrorism; Al Qaeda; United States; Geopolitics; Secession; Social movements ER - TY - JOUR T1 - Platform technologies for tubular organ regeneration AN - 831146420; 13809046 AB - As a result of recent successes in regenerative medicine approaches to engineering multiple disparate tubular organs, methodology commonalities are emerging. Principal themes include the importance of a biodegradable scaffold seeded with a population of smooth muscle cells. Such composites trigger a regenerative response following in vivo implantation, resulting in de novo organogenesis. In this review, we examine bladder regeneration as a foundational platform technology to highlight key principles applicable to the regeneration of any tubular organ, and illustrate how these general concepts underlie current strategies to regenerate components of gastrointestinal, vascular, pulmonary and genitourinary systems. We focus on identifying the elements of this platform that have facilitated the transition of tubular organ regeneration from academic proof-of-concept to commercial viability. JF - Trends in Biotechnology AU - Basu, Joydeep AU - Ludlow, John W AD - Bioprocess Research and Assay Development, Tengion Inc., 3929 Westpoint Blvd., Suite G, Winston-Salem, NC 27103, USA, joydeep.basu@tengion.com PY - 2010 SP - 526 EP - 533 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 28 IS - 10 SN - 0167-7799, 0167-7799 KW - Microbiology Abstracts B: Bacteriology; Biotechnology and Bioengineering Abstracts KW - Smooth muscle KW - Organogenesis KW - Lung KW - Urinary bladder KW - Reviews KW - Regeneration KW - Biodegradability KW - scaffolds KW - W 30900:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/831146420?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Trends+in+Biotechnology&rft.atitle=Platform+technologies+for+tubular+organ+regeneration&rft.au=Basu%2C+Joydeep%3BLudlow%2C+John+W&rft.aulast=Basu&rft.aufirst=Joydeep&rft.date=2010-01-01&rft.volume=28&rft.issue=10&rft.spage=526&rft.isbn=&rft.btitle=&rft.title=Trends+in+Biotechnology&rft.issn=01677799&rft_id=info:doi/10.1016%2Fj.tibtech.2010.07.007 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-08-01 N1 - Last updated - 2016-01-06 N1 - SubjectsTermNotLitGenreText - Smooth muscle; Organogenesis; Urinary bladder; Lung; Reviews; Regeneration; Biodegradability; scaffolds DO - http://dx.doi.org/10.1016/j.tibtech.2010.07.007 ER - TY - JOUR T1 - Using Language Features in Teaching and Curriculum Development to Improve Language Proficiency AN - 822513313; 201022698 AB - The quest for improving foreign language proficiency continues to be the subject of heated debate in many foreign language-teaching programs. Recently, this issue has also been the focus of attention of many teachers, curriculum developers, and administrators at the Defense Language Institute Foreign Language Center (DLIFLC). This concern has manifested itself in many professional meetings, training workshops, seminars, and conferences that are entirely devoted to discussing this issue and to making relevant decisions. Adapted from the source document JF - Dialog on Language Instruction AU - Elghannam, Alaa AD - Defense Language Instit Foreign Language Center, Presidio Monterey, CA alaa.elghannam@us.army.mil Y1 - 2010///0, PY - 2010 DA - 0, 2010 SP - 39 EP - 56 VL - 21 IS - 1-2 KW - Language Teaching Methods (44100) KW - Second Language Instruction (75700) KW - Second Language Teachers (76120) KW - Curriculum Planning (16780) KW - Language Proficiency (43570) KW - article KW - 4112: applied linguistics; non-native language instruction (languages other than English) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/822513313?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Allba&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Dialog+on+Language+Instruction&rft.atitle=Using+Language+Features+in+Teaching+and+Curriculum+Development+to+Improve+Language+Proficiency&rft.au=Elghannam%2C+Alaa&rft.aulast=Elghannam&rft.aufirst=Alaa&rft.date=2010-01-01&rft.volume=21&rft.issue=1-2&rft.spage=39&rft.isbn=&rft.btitle=&rft.title=Dialog+on+Language+Instruction&rft.issn=&rft_id=info:doi/ LA - English DB - Linguistics and Language Behavior Abstracts (LLBA) N1 - Date revised - 2010-12-01 N1 - Last updated - 2016-09-27 N1 - CODEN - DLINFQ N1 - SubjectsTermNotLitGenreText - Second Language Instruction (75700); Language Teaching Methods (44100); Curriculum Planning (16780); Language Proficiency (43570); Second Language Teachers (76120) ER - TY - JOUR T1 - Seven Wonders of Russia: Student-Centered Project on Culture and Geography AN - 822513264; 201022708 AB - The purpose of this article is to familiarize DLI teachers with a highly-practical student-centered project in the target language that can assist with introducing the Area Studies (culture and geography) of the target-language country(s) in an interactive way by applying available technology. The project is flexible and can be applied to any language being taught at DLI. It describes the selection of materials, step-by-step instructions on possible project organization, as well as scheduling. Adapted from the source document JF - Dialog on Language Instruction AU - McCaw, Tatiana AU - Slutsky, Leonid AD - Dept Russian, Defense Language Instit Foreign Language Center, Presidio Monterey, CA mccaw@us.army.mil Y1 - 2010///0, PY - 2010 DA - 0, 2010 SP - 27 EP - 38 VL - 21 IS - 1-2 KW - Russia (74400) KW - Language Teaching Methods (44100) KW - Second Language Instruction (75700) KW - Content Area Instruction (15190) KW - Russian (74450) KW - Cultural Instruction (16580) KW - article KW - 4112: applied linguistics; non-native language instruction (languages other than English) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/822513264?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Allba&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Sexually+Transmitted+Diseases&rft.atitle=Cost+and+Effectiveness+of+Chlamydia+Screening+among+Male+Military+Recruits%3A+Markov+Modeling+of+Complications+Averted+through+Notification+of+Prior+Female+Partners&rft.au=Nevin%2C+Remington+L%3BShuping%2C+Eric+E%3BFrick%2C+Kevin+D%3BGaydos%2C+Joel+C%3BGaydos%2C+Charlotte+A&rft.aulast=Nevin&rft.aufirst=Remington&rft.date=2008-08-01&rft.volume=35&rft.issue=8&rft.spage=705&rft.isbn=&rft.btitle=&rft.title=Sexually+Transmitted+Diseases&rft.issn=01485717&rft_id=info:doi/10.1097%2FOLQ.0b013e31816d1f55 LA - English DB - Linguistics and Language Behavior Abstracts (LLBA) N1 - Date revised - 2010-12-01 N1 - Last updated - 2016-09-27 N1 - CODEN - DLINFQ N1 - SubjectsTermNotLitGenreText - Second Language Instruction (75700); Russian (74450); Cultural Instruction (16580); Russia (74400); Language Teaching Methods (44100); Content Area Instruction (15190) ER - TY - JOUR T1 - Stationarity; wanted dead or alive AN - 821967952; 2011-009060 AB - Aligning engineering practices with natural process behavior would appear, on its face, to be a prudent and reasonable course of action. However, given what we know about the long-term characteristics of hydroclimatic processes, does the prudent and reasonable course necessarily portend improved water management practices? We argue herein that it does not, based on three aspects of observed hydroclimatic variability and statistical inference: Hurst-Kolmogorov phenomenon; long-term persistence and the complications it introduces with respect to statistical understanding; and the arbitrariness of sampling choices with respect to trend testing. Sometimes it is better to employ a simple model with well-understood flaws than a sophisticated model whose correspondence to reality is uncertain. JF - Information Series - Colorado Water Resources Research Institute AU - Lins, Harry AU - Cohn, Tim A2 - Olsen, J. Rolf A2 - Kiang, Julie A2 - Waskom, Reagan Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 60 EP - 64 PB - Colorado State University, Colorado Water Resources Institute, Fort Collins, CO VL - 109 SN - 0198-8735, 0198-8735 KW - United States KW - hydrology KW - ice cores KW - nonstationary processes KW - statistical analysis KW - rivers and streams KW - stationary processes KW - climate change KW - temperature KW - case studies KW - Antarctica KW - streamflow KW - stochastic processes KW - sampling KW - ice KW - Vostok Station KW - 21:Hydrogeology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/821967952?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Information+Series+-+Colorado+Water+Resources+Research+Institute&rft.atitle=Stationarity%3B+wanted+dead+or+alive&rft.au=Lins%2C+Harry%3BCohn%2C+Tim&rft.aulast=Lins&rft.aufirst=Harry&rft.date=2010-01-01&rft.volume=109&rft.issue=&rft.spage=60&rft.isbn=&rft.btitle=&rft.title=Information+Series+-+Colorado+Water+Resources+Research+Institute&rft.issn=01988735&rft_id=info:doi/ L2 - http://cwrri.colostate.edu/publications.asp?pubs=is LA - English DB - GeoRef N1 - Conference title - Workshop on Nonstationarity, hydrologic frequency analysis, and water management N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Number of references - 7 N1 - PubXState - CO N1 - Document feature - illus. incl. 1 table N1 - Last updated - 2012-06-07 N1 - CODEN - ISCIDF N1 - SubjectsTermNotLitGenreText - Antarctica; case studies; climate change; hydrology; ice; ice cores; nonstationary processes; rivers and streams; sampling; stationary processes; statistical analysis; stochastic processes; streamflow; temperature; United States; Vostok Station ER - TY - JOUR T1 - A perspective on nonstationarity and water management AN - 821967940; 2011-009059 AB - This essay offers some perspectives on issue of nonstationarity due to climate change as a topic of concern to the water management community. Some of the challenges are the following: water management concerns are often focused on the tails of the probability distribution but the ability to predict or detect change is most effective on the central tendency. Hydrologic conditions can be non-stationary due to many types of human actions, but climate change presents special challenges because our ability to predict its impact is still so limited. The inquiry into this issue should follow both an empirical approach and a modeling approach. Precipitation analysis is useful, but it is not a substitute for the analysis of streamflow. The inquiry is difficult because it is so difficult to distinguish between persistence and human-induced trend. There is need for a major emphasis on research on decision-making in the face of this large climate change uncertainty. Finally, the issue of climate change should cause us to place increased emphasis on the continuity of hydrologic records and on the human capital needed to perform continued planning and analysis in the changing world we face. JF - Information Series - Colorado Water Resources Research Institute AU - Hirsch, Robert M A2 - Olsen, J. Rolf A2 - Kiang, Julie A2 - Waskom, Reagan Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 5 EP - 14 PB - Colorado State University, Colorado Water Resources Institute, Fort Collins, CO VL - 109 SN - 0198-8735, 0198-8735 KW - hydrology KW - annual variations KW - nonstationary processes KW - human activity KW - rivers and streams KW - water management KW - prediction KW - environmental effects KW - climate change KW - models KW - climate effects KW - discharge KW - water resources KW - 21:Hydrogeology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/821967940?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Information+Series+-+Colorado+Water+Resources+Research+Institute&rft.atitle=A+perspective+on+nonstationarity+and+water+management&rft.au=Hirsch%2C+Robert+M&rft.aulast=Hirsch&rft.aufirst=Robert&rft.date=2010-01-01&rft.volume=109&rft.issue=&rft.spage=5&rft.isbn=&rft.btitle=&rft.title=Information+Series+-+Colorado+Water+Resources+Research+Institute&rft.issn=01988735&rft_id=info:doi/ L2 - http://cwrri.colostate.edu/publications.asp?pubs=is LA - English DB - GeoRef N1 - Conference title - Workshop on Nonstationarity, hydrologic frequency analysis, and water management N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Number of references - 10 N1 - PubXState - CO N1 - Document feature - illus. N1 - Last updated - 2012-06-07 N1 - CODEN - ISCIDF N1 - SubjectsTermNotLitGenreText - annual variations; climate change; climate effects; discharge; environmental effects; human activity; hydrology; models; nonstationary processes; prediction; rivers and streams; water management; water resources ER - TY - JOUR T1 - Workshop on Nonstationarity, hydrologic frequency analysis, and water management AN - 821967930; 2011-009058 JF - Information Series - Colorado Water Resources Research Institute A2 - Olsen, J. Rolf A2 - Kiang, Julie A2 - Waskom, Reagan Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 304 PB - Colorado State University, Colorado Water Resources Institute, Fort Collins, CO VL - 109 SN - 0198-8735, 0198-8735 KW - hydrology KW - symposia KW - stochastic processes KW - nonstationary processes KW - statistical analysis KW - climate effects KW - water management KW - frequency KW - climate change KW - 21:Hydrogeology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/821967930?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Information+Series+-+Colorado+Water+Resources+Research+Institute&rft.atitle=Workshop+on+Nonstationarity%2C+hydrologic+frequency+analysis%2C+and+water+management&rft.au=&rft.aulast=&rft.aufirst=&rft.date=2010-01-01&rft.volume=109&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Information+Series+-+Colorado+Water+Resources+Research+Institute&rft.issn=01988735&rft_id=info:doi/ L2 - http://cwrri.colostate.edu/publications.asp?pubs=is LA - English DB - GeoRef N1 - Conference title - Workshop on Nonstationarity, hydrologic frequency analysis, and water management N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - PubXState - CO N1 - Document feature - illus. incl. tables, sketch maps N1 - SuppNotes - Individual papers within scope are cited separately N1 - Last updated - 2012-06-07 N1 - CODEN - ISCIDF N1 - SubjectsTermNotLitGenreText - climate change; climate effects; frequency; hydrology; nonstationary processes; statistical analysis; stochastic processes; symposia; water management ER - TY - JOUR T1 - Planning hydrology based on blends of instrumental records, paleoclimate, and projected climate information AN - 821967341; 2011-009062 AB - Planning studies are critical during evaluation of changes to water supply, demands, or reservoir operating policies. These studies allow water management agencies, such as the Bureau of Reclamation, to evaluate the impacts of proposed changes in a river basin system under their management and convey their findings to critical stakeholders and the general public. Planning studies typically structure an assumption of future water supply, demands, and reservoir operations and represent changes to one or a combination of these assumptions versus present conditions. Future water supply assumption or planning hydrologies are typically developed from information based on observed gauge records. Planning hydrologies based on these data assume that future conditions can be represented by the climate events of the observed past. Recent evidence has shown the observed past may not provide an adequate proxy of future climate. It is becoming increasing difficult to depend on planning hydrologies that are solely based on information provided by the recent observed past. In the Colorado River Basin, until 2007 planning studies only utilized a naturalized flow dataset that extended back to 1906. This record was built from observed records that capture the hydrologic variability observed over the last century. Though the Colorado River Basin has a "long" observed dataset, in the eyes of many practitioners the basin has been recently enduring a drought that is unprecedented in its observed record. The current drought that began in 2000 continues today producing the lowest ten year average flow in the last hundred years. This unprecedented drought has provided an excellent opportunity for Reclamation to explore alternate methods to develop planning hydrologies that go beyond dependence on the observed past. As a first step Reclamation sought to re-introduce paleo-reconstructed streamflows. These reconstructions provide a window into the distant past, significantly enhancing relevant frequency characteristics in a planning hydrology and incorporating climate information from the past one thousand years rather than just the last one hundred. Such reconstructions have been available in the Colorado River basin since 1976 but have not gained wide acceptance in planning studies. Though reconstructed streamflows provide rich information and should be incorporated in planning hydrologies, the magnitudes of reconstructed streamflow can have a high degree of uncertainty. When creating a reconstruction a regression model is fit to the observed streamflow with a collection of tree ring observations as the predictors. This fitted model is then used to estimate streamflows in the pre-observational period using the tree ring observations. The reconstructed streamflows can be sensitive to the choice of model as demonstrated by Hidalgo et al. (2000). This apparent weakness of the paleo reconstructed flow data has rendered their use in a water resources planning context questionable, despite the availability of paleo reconstructed data for many decades. Despite these apparent weaknesses, few argue about the duration and frequency of dry and wet (i.e., the hydrologic state) periods from the reconstructions. Recognizing the limitations of relying on only the instrumental record for long-term planning studies, Reclamation devised a framework to combine the long paleo reconstructed streamflow information of lower reliability with the shorter but reliable observational data. The framework blends paleoreconstructed hydrologic state (i.e., wet or dry) with instrumental records magnitudes. With these datasets the framework addresses generating simulations for planning studies with drought and surplus spells that demonstrate the persistence underlying the lengthy paleo reconstructions. JF - Information Series - Colorado Water Resources Research Institute AU - Prairie, James A2 - Olsen, J. Rolf A2 - Kiang, Julie A2 - Waskom, Reagan Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 218 EP - 228 PB - Colorado State University, Colorado Water Resources Institute, Fort Collins, CO VL - 109 SN - 0198-8735, 0198-8735 KW - United States KW - models KW - hydrology KW - Colorado River basin KW - Western U.S. KW - sensitivity analysis KW - climate effects KW - water management KW - prediction KW - paleoclimatology KW - climate change KW - 21:Hydrogeology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/821967341?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Information+Series+-+Colorado+Water+Resources+Research+Institute&rft.atitle=Planning+hydrology+based+on+blends+of+instrumental+records%2C+paleoclimate%2C+and+projected+climate+information&rft.au=Prairie%2C+James&rft.aulast=Prairie&rft.aufirst=James&rft.date=2010-01-01&rft.volume=109&rft.issue=&rft.spage=218&rft.isbn=&rft.btitle=&rft.title=Information+Series+-+Colorado+Water+Resources+Research+Institute&rft.issn=01988735&rft_id=info:doi/ L2 - http://cwrri.colostate.edu/publications.asp?pubs=is LA - English DB - GeoRef N1 - Conference title - Workshop on Nonstationarity, hydrologic frequency analysis, and water management N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - PubXState - CO N1 - Document feature - illus. N1 - Last updated - 2012-06-07 N1 - CODEN - ISCIDF N1 - SubjectsTermNotLitGenreText - climate change; climate effects; Colorado River basin; hydrology; models; paleoclimatology; prediction; sensitivity analysis; United States; water management; Western U.S. ER - TY - JOUR T1 - Climate change, atmospheric rivers, and floods in California; a multi-model ensemble analysis of projections of storm frequency and magnitude changes AN - 821967073; 2011-009061 AB - Several recent studies have shown the important role that "atmospheric rivers" (ARs) of concentrated near-surface water-vapor transport above the Pacific Ocean play in historic storms and floods in the West Coast states. By delivering large masses of warm, moist air (sometimes directly from the Tropics), ARs establish conditions for the kinds of high snowlines and copious rainfall that have caused the largest historical storms in California, Oregon, and Washington. In many California rivers, essentially all major historical floods have been associated with AR conditions. Thus the future of these storms is likely to have an important influence on nonstationarities of flood frequencies and magnitudes in the face of projected 21st century climate changes. As a concrete example of the kinds of storm changes that may underlie future flood-frequency changes, the occurrence of such storms in historical observations and in a 7-model ensemble of historical-climate and projected future-climate simulations has been evaluated. Under an A2 greenhouse-gas emissions scenario (with emissions accelerating throughout the 21st century), average AR statistics do not change much in most climate models; however, extremes change notably. Years with many AR episodes increase, ARs with higher-than-historical water-vapor transport rates increase, and AR storm-temperatures increase. Furthermore, the peak season within which most ARs occur is commonly projected to lengthen, extending the flood-hazard season. All of these tendencies could increase opportunities for both more frequent and more severe floods in California under projected climate changes. JF - Information Series - Colorado Water Resources Research Institute AU - Dettinger, Michael A2 - Olsen, J. Rolf A2 - Kiang, Julie A2 - Waskom, Reagan Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 158 EP - 166 PB - Colorado State University, Colorado Water Resources Institute, Fort Collins, CO VL - 109 SN - 0198-8735, 0198-8735 KW - United States KW - hydrology KW - general circulation models KW - numerical models KW - geologic hazards KW - data processing KW - prediction KW - water vapor KW - atmospheric precipitation KW - frequency KW - climate change KW - California KW - transport KW - atmospheric transport KW - Pacific Ocean KW - digital simulation KW - floods KW - climate effects KW - risk assessment KW - storms KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/821967073?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Information+Series+-+Colorado+Water+Resources+Research+Institute&rft.atitle=Climate+change%2C+atmospheric+rivers%2C+and+floods+in+California%3B+a+multi-model+ensemble+analysis+of+projections+of+storm+frequency+and+magnitude+changes&rft.au=Dettinger%2C+Michael&rft.aulast=Dettinger&rft.aufirst=Michael&rft.date=2010-01-01&rft.volume=109&rft.issue=&rft.spage=158&rft.isbn=&rft.btitle=&rft.title=Information+Series+-+Colorado+Water+Resources+Research+Institute&rft.issn=01988735&rft_id=info:doi/ L2 - http://cwrri.colostate.edu/publications.asp?pubs=is LA - English DB - GeoRef N1 - Conference title - Workshop on Nonstationarity, hydrologic frequency analysis, and water management N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Number of references - 22 N1 - PubXState - CO N1 - Document feature - illus. incl. 2 tables N1 - Last updated - 2012-06-07 N1 - CODEN - ISCIDF N1 - SubjectsTermNotLitGenreText - atmospheric precipitation; atmospheric transport; California; climate change; climate effects; data processing; digital simulation; floods; frequency; general circulation models; geologic hazards; hydrology; numerical models; Pacific Ocean; prediction; risk assessment; storms; transport; United States; water vapor ER - TY - JOUR T1 - Tests of Sommerfeld ground wave theory using ground-penetrating radar pulses AN - 818637099; 2011-006633 JF - International Conference on Ground Penetrating Radar AU - Arcone, Steven A AU - Liu, Lanbo AU - Persico, Raffaele Y1 - 2010 PY - 2010 DA - 2010 EP - unpaginated PB - [varies], [location varies] VL - 13 KW - United States KW - Fairbanks Alaska KW - electrical properties KW - Sommerfeld Theory KW - guided waves KW - ground-penetrating radar KW - radar methods KW - elastic waves KW - Fort Greely Alaska KW - attenuation KW - surface waves KW - dielectric properties KW - ice KW - East-Central Alaska KW - theoretical models KW - ground ice KW - Alaska KW - seismic waves KW - military facilities KW - frozen ground KW - 20:Applied geophysics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/818637099?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Conference+on+Ground+Penetrating+Radar&rft.atitle=Tests+of+Sommerfeld+ground+wave+theory+using+ground-penetrating+radar+pulses&rft.au=Arcone%2C+Steven+A%3BLiu%2C+Lanbo%3BPersico%2C+Raffaele&rft.aulast=Arcone&rft.aufirst=Steven&rft.date=2010-01-01&rft.volume=13&rft.issue=&rft.spage=&rft.isbn=9781424446056&rft.btitle=&rft.title=International+Conference+on+Ground+Penetrating+Radar&rft.issn=&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Thirteenth international conference on Ground penetrating radar (GPR 2010) N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Number of references - 14 N1 - Document feature - illus. N1 - Last updated - 2012-06-07 N1 - CODEN - #06652 N1 - SubjectsTermNotLitGenreText - Alaska; attenuation; dielectric properties; East-Central Alaska; elastic waves; electrical properties; Fairbanks Alaska; Fort Greely Alaska; frozen ground; ground ice; ground-penetrating radar; guided waves; ice; military facilities; radar methods; seismic waves; Sommerfeld Theory; surface waves; theoretical models; United States ER - TY - JOUR T1 - Complex permittivity of common minerals and one soil at low water contents AN - 818637082; 2011-006631 JF - International Conference on Ground Penetrating Radar AU - Arcone, Steven A AU - Boitnott, Ginger E AU - Persico, Raffaele Y1 - 2010 PY - 2010 DA - 2010 EP - unpaginated PB - [varies], [location varies] VL - 13 KW - soils KW - silicates KW - electrical conductivity KW - sulfates KW - silica minerals KW - ground-penetrating radar KW - radar methods KW - Desert soils KW - dielectric constant KW - calcite KW - attenuation KW - gypsum KW - quartz KW - water content KW - sheet silicates KW - framework silicates KW - feldspar group KW - carbonates KW - 01A:General mineralogy KW - 25:Soils UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/818637082?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Conference+on+Ground+Penetrating+Radar&rft.atitle=Complex+permittivity+of+common+minerals+and+one+soil+at+low+water+contents&rft.au=Arcone%2C+Steven+A%3BBoitnott%2C+Ginger+E%3BPersico%2C+Raffaele&rft.aulast=Arcone&rft.aufirst=Steven&rft.date=2010-01-01&rft.volume=13&rft.issue=&rft.spage=&rft.isbn=9781424446056&rft.btitle=&rft.title=International+Conference+on+Ground+Penetrating+Radar&rft.issn=&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Thirteenth international conference on Ground penetrating radar (GPR 2010) N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Number of references - 13 N1 - Document feature - illus. incl. 2 tables N1 - Last updated - 2012-06-07 N1 - CODEN - #06652 N1 - SubjectsTermNotLitGenreText - attenuation; calcite; carbonates; Desert soils; dielectric constant; electrical conductivity; feldspar group; framework silicates; ground-penetrating radar; gypsum; quartz; radar methods; sheet silicates; silica minerals; silicates; soils; sulfates; water content ER - TY - JOUR T1 - Effects of surface topography and wind on reflection horizons in ice sheets AN - 818637035; 2011-006632 AB - Radar horizons within the great ice sheets of Antarctica are distorted by greater snow deposition on windward than on leeward slopes. In West Antarctica, this effect can change horizon depth by tens of meters but still leave the horizons surface-conformable and continuous for hundreds of kilometers. When viewed on a scale of tens of kilometers, the additional effect of ice speed makes horizons appear falsely recumbent and suggests false historical changes in ice speed. In large regions of the high East Antarctica plateau, deposition occurs only on windward slopes to form prograding bedding sequences up to tens of kilometers long and hundreds of meters thick. Beneath the leeward slopes, long-term metamorphism transforms the bedded strata into unconformable and unstratified pseudolayers that grow with burial, merge with others, form concatenated layers more than 70 km long and over 100 m thick, and generally account for all major englacial horizons. For the largest sequences, the bed topography controls the surface topography and in large part, the way accumulation is distributed on the high plateaus. JF - International Conference on Ground Penetrating Radar AU - Arcone, Steven A AU - Jacobel, Robert AU - Persico, Raffaele Y1 - 2010 PY - 2010 DA - 2010 EP - unpaginated PB - [varies], [location varies] VL - 13 KW - snow cover KW - ice cover thickness KW - ground-penetrating radar KW - radar methods KW - ice cover KW - glaciers KW - Antarctic Platform KW - ice sheets KW - observations KW - Antarctic ice sheet KW - ice movement KW - topography KW - Antarctica KW - ice KW - snow KW - velocity KW - thickness KW - glacial geology KW - meteorology KW - winds KW - 24:Quaternary geology KW - 20:Applied geophysics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/818637035?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Conference+on+Ground+Penetrating+Radar&rft.atitle=Effects+of+surface+topography+and+wind+on+reflection+horizons+in+ice+sheets&rft.au=Arcone%2C+Steven+A%3BJacobel%2C+Robert%3BPersico%2C+Raffaele&rft.aulast=Arcone&rft.aufirst=Steven&rft.date=2010-01-01&rft.volume=13&rft.issue=&rft.spage=&rft.isbn=9781424446056&rft.btitle=&rft.title=International+Conference+on+Ground+Penetrating+Radar&rft.issn=&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Thirteenth international conference on Ground penetrating radar (GPR 2010) N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2011-01-01 N1 - Number of references - 12 N1 - Document feature - illus. N1 - Last updated - 2012-06-07 N1 - CODEN - #06652 N1 - SubjectsTermNotLitGenreText - Antarctic ice sheet; Antarctic Platform; Antarctica; glacial geology; glaciers; ground-penetrating radar; ice; ice cover; ice cover thickness; ice movement; ice sheets; meteorology; observations; radar methods; snow; snow cover; thickness; topography; velocity; winds ER - TY - JOUR T1 - The gulf states in the shadow of Iran - Tehran menaces its neighbors AN - 762958279; 4125571 JF - Middle East quarterly AU - Knapp, Patrick AD - Minnesota Army National Guard Y1 - 2010/01// PY - 2010 DA - Jan 2010 SP - 49 EP - 60 VL - 17 IS - 1 SN - 1073-9467, 1073-9467 KW - Political Science KW - Foreign policy KW - Iran KW - Foreign affairs KW - Conflict KW - Political conflicts UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/762958279?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Middle+East+quarterly&rft.atitle=The+gulf+states+in+the+shadow+of+Iran+-+Tehran+menaces+its+neighbors&rft.au=Knapp%2C+Patrick&rft.aulast=Knapp&rft.aufirst=Patrick&rft.date=2010-01-01&rft.volume=17&rft.issue=1&rft.spage=49&rft.isbn=&rft.btitle=&rft.title=Middle+East+quarterly&rft.issn=10739467&rft_id=info:doi/ LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 2698; 5166; 5200 5574 10472; 9666 2698; 181 254 ER - TY - JOUR T1 - Influence of bacterial biofilms on Bacillus globigii spore viability in model chlorinated water distribution systems AN - 762269207; 13725928 AB - Viability of Bacillus globigii spores in chlorinated polyvinyl chloride (PVC) pipe loop systems were examined under oligotrophic conditions. Three 2.5 cm X 10 m pipe loops having poised free chlorine concentrations of 0.,0.5, and 1.0 mg/L were seeded with 3.0 X 108 B. globigii spores each and viability was assessed over a 21 day period in both the recirculating waters and within the biofilms associated with pipe wall surfaces. After 10 min of exposure, viable spores were found to be associated within the pipe biofilms. In the untreated pipe loop spore counts remained statistically consistent in both the bulk water and biofilm until 1.0 mg/L free chlorine was introduced, then spores were completely inactivated in less than seven days. Spores within the pipe loop poised at 0.5 mg/L free chlorine showed a 7.6-log10 inactivation in the bulk water phase, but only a 2.7-log10 inactivation was observed within the biofilm after 14 days of treatment. Complete inactivation was observed in the 1.0 mg/L free chlorine system in both the biofilm and the bulk water phase in less than 10 min. These data demonstrated that B. globigii spores were readily incorporated into PVC pipe biofilms, which decreased spore inactivation nearly five orders of magnitude under moderate free chlorine concentrations. JF - Water Science & Technology: Water Supply AU - Arnett, C M AU - Beckman, A M AU - Ginsberg, M D AU - Hock, V F AD - US Army Engineer Research & Development Center, Construction Engineering Research Laboratory, 2902 Newmark Dr, Champaign, IL 61822, USA : clint.arnett super(s)ace.army.mil; vincent.f.hock super(s)ace.army.mil; mark.d.ginsber super(s)ace.army.mil; anne.beckman super(s)ace.army.mil, clint.arnett@usace.army.mil Y1 - 2010///0, PY - 2010 DA - 0, 2010 SP - 277 EP - 285 PB - IWA Publishing, Alliance House London SW1H 0QS UK VL - 10 IS - 1 SN - 1606-9749, 1606-9749 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology; Water Resources Abstracts; Environment Abstracts; Aqualine Abstracts KW - inactivation KW - Chlorophylls KW - Water Supply KW - Chlorides KW - Chlorine KW - Water supplies KW - Exposure KW - Biofilms KW - Bacillus KW - Modelling KW - Bacillus globigii KW - Pipes KW - Data processing KW - polyvinyl chloride KW - Model Studies KW - Water supply KW - Spores KW - Q5 08503:Characteristics, behavior and fate KW - A 01450:Environmental Pollution & Waste Treatment KW - J 02320:Cell Biology KW - SW 3060:Water treatment and distribution KW - AQ 00008:Effects of Pollution KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/762269207?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Water+Science+%26+Technology%3A+Water+Supply&rft.atitle=Influence+of+bacterial+biofilms+on+Bacillus+globigii+spore+viability+in+model+chlorinated+water+distribution+systems&rft.au=Arnett%2C+C+M%3BBeckman%2C+A+M%3BGinsberg%2C+M+D%3BHock%2C+V+F&rft.aulast=Arnett&rft.aufirst=C&rft.date=2010-01-01&rft.volume=10&rft.issue=1&rft.spage=277&rft.isbn=&rft.btitle=&rft.title=Water+Science+%26+Technology%3A+Water+Supply&rft.issn=16069749&rft_id=info:doi/10.2166%2Fws.2010.036 L2 - http://www.iwaponline.com/ws/01003/ws010030277.htm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-10-01 N1 - Last updated - 2016-03-17 N1 - SubjectsTermNotLitGenreText - Chlorophylls; Biofilms; Spores; Modelling; Water supply; Data processing; polyvinyl chloride; Chlorine; Water supplies; inactivation; Pipes; Chlorides; Exposure; Water Supply; Bacillus; Model Studies; Bacillus globigii DO - http://dx.doi.org/10.2166/ws.2010.036 ER - TY - JOUR T1 - Potential impact of sea level rise on coastal surges in southeast Louisiana AN - 759308110; 13012421 AB - Potential impacts of 0.5 and 1.0m of relative sea level rise (RSLR) on hurricane surge and waves in southeast Louisiana are investigated using the numerical storm surge model ADCIRC and the nearshore spectral wave model STWAVE. The models were applied for six hypothetic hurricanes that produce approximately 100yr water levels in southeastern Louisiana. In areas of maximum surge, the impact of RSLR on surge was generally linear (equal to the RSLR). In wetland or wetland-fronted areas of moderate peak surges (2-3m), the surge levels were increased by as much as 1-3m (in addition to the RSLR). The surge increase is as much as double and triple the RSLR over broad areas and as much as five times the RSLR in isolated areas. Waves increase significantly in shallow areas due to the combined increases in water depth due to RSLR and surge increases. Maximum increases in wave height for the modeled storms were 1-1.5m. Surge propagation over broad, shallow, wetland areas is highly sensitive to RSLR. Wave heights also generally increased for all RSLR cases. These increases were significant (0.5-1.5m for 1m RSLR), but less dramatic than the surge increases. JF - Ocean Engineering AU - Smith, Jane McKee AU - Cialone, Mary A AU - Wamsley, Ty V AU - McAlpin, Tate O AD - US Army Engineer Research and Development Center, Coastal and Hydraulics Laboratory, 3909 Halls Ferry Road, Vicksburg, MS 39180-6199, USA, Jane.M.Smith@usace.army.mil Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 37 EP - 47 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK VL - 37 IS - 1 SN - 0029-8018, 0029-8018 KW - Water Resources Abstracts; Oceanic Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources KW - Hurricane KW - Katrina KW - Sea level rise KW - Southeast Louisiana KW - Storm surge KW - Waves KW - ADCIRC KW - STWAVE KW - IPET KW - Marine KW - ASW, USA, Louisiana KW - Offshore engineering KW - Mathematical models KW - Surges KW - Storms KW - Model Studies KW - Wave Height KW - Sea Level KW - Hurricanes KW - Coastal zone KW - Storm surges KW - Oceans KW - Wave height KW - Wetlands KW - Hurricane waves KW - Sea level changes KW - SW 0890:Estuaries KW - Q2 09167:Tides, surges and sea level KW - O 2070:Meteorology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/759308110?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ocean+Engineering&rft.atitle=Potential+impact+of+sea+level+rise+on+coastal+surges+in+southeast+Louisiana&rft.au=Smith%2C+Jane+McKee%3BCialone%2C+Mary+A%3BWamsley%2C+Ty+V%3BMcAlpin%2C+Tate+O&rft.aulast=Smith&rft.aufirst=Jane&rft.date=2010-01-01&rft.volume=37&rft.issue=1&rft.spage=37&rft.isbn=&rft.btitle=&rft.title=Ocean+Engineering&rft.issn=00298018&rft_id=info:doi/10.1016%2Fj.oceaneng.2009.07.008 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-10-01 N1 - Last updated - 2016-02-04 N1 - SubjectsTermNotLitGenreText - Coastal zone; Offshore engineering; Mathematical models; Storm surges; Wave height; Surges; Hurricane waves; Wetlands; Sea level changes; Sea Level; Hurricanes; Oceans; Waves; Storms; Wave Height; Model Studies; ASW, USA, Louisiana; Marine DO - http://dx.doi.org/10.1016/j.oceaneng.2009.07.008 ER - TY - JOUR T1 - Development of storm surge which led to flooding in St. Bernard Polder during Hurricane Katrina AN - 759307561; 13012415 AB - Hurricane Katrina caused devastating flooding in St. Bernard Parish, Louisiana. Storm surge surrounded the polder that comprises heavily populated sections of the Parish in addition to the Lower 9th Ward section of Orleans Parish. Surge propagated along several pathways to reach levees and walls around the polder's periphery. Extreme water levels led to breaches in the levee/wall system which, along with wave overtopping and steady overflow, led to considerable flood water entering the polder. Generation and evolution of the storm surge as it propagated into the region is examined using results from the SL15 regional application of the ADCIRC storm surge model. Fluxes of water into the region through navigation channels are compared to fluxes which entered through Lake Borgne and over inundated wetlands surrounding the lake. Fluxes through Lake Borgne and adjacent wetlands were found to be the predominant source of water reaching the region. Various sources of flood water along the polder periphery are examined. Flood water primarily entered through the east and west sides of the polder. Different peak surges and hydrograph shapes were experienced along the polder boundaries, and reasons for the spatial variability in surge conditions are discussed. JF - Ocean Engineering AU - Ebersole, BA AU - Westerink, J J AU - Bunya, S AU - Dietrich, J C AU - Cialone, MA AD - Coastal and Hydraulics Laboratory, U.S. Army Engineer Research and Development Center, 3909 Halls Ferry Road, Vicksburg, MS 39180-6199, USA Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 91 EP - 103 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK VL - 37 IS - 1 SN - 0029-8018, 0029-8018 KW - Water Resources Abstracts; Oceanic Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources KW - Hurricane KW - Katrina KW - Louisiana KW - Storm KW - Surge KW - Inundation KW - Flooding KW - ADCIRC KW - Marine KW - Overflow KW - ASW, USA, Louisiana KW - Surges KW - Levees KW - Polders KW - Hurricanes KW - Lakes KW - Storm surges KW - Floods KW - Storm Surges KW - Wetlands KW - Overtopping KW - O 6060:Coastal Zone Resources and Management KW - Q2 09281:General KW - SW 6010:Structures UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/759307561?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ocean+Engineering&rft.atitle=Development+of+storm+surge+which+led+to+flooding+in+St.+Bernard+Polder+during+Hurricane+Katrina&rft.au=Ebersole%2C+BA%3BWesterink%2C+J+J%3BBunya%2C+S%3BDietrich%2C+J+C%3BCialone%2C+MA&rft.aulast=Ebersole&rft.aufirst=BA&rft.date=2010-01-01&rft.volume=37&rft.issue=1&rft.spage=91&rft.isbn=&rft.btitle=&rft.title=Ocean+Engineering&rft.issn=00298018&rft_id=info:doi/10.1016%2Fj.oceaneng.2009.08.013 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-10-01 N1 - Last updated - 2016-02-04 N1 - SubjectsTermNotLitGenreText - Overflow; Hurricanes; Storm surges; Surges; Levees; Flooding; Wetlands; Polders; Overtopping; Lakes; Floods; Storm Surges; ASW, USA, Louisiana; Marine DO - http://dx.doi.org/10.1016/j.oceaneng.2009.08.013 ER - TY - JOUR T1 - The permafrost tunnel near Fox, Alaska expansion project AN - 756293418; 2010-084631 JF - Abstracts - European Conference on Permafrost AU - Sturm, M AU - Nelson, F E AU - Cysewski, M H AU - Anonymous Y1 - 2010 PY - 2010 DA - 2010 SP - 337 PB - [varies], [varies] VL - 3 KW - United States KW - Alaska Permafrost Research Center KW - Fairbanks Alaska KW - permafrost KW - monitoring KW - engineering properties KW - government agencies KW - geophysical methods KW - U. S. Bureau of Mines KW - research KW - excavations KW - structures KW - models KW - detection KW - U. S. Army Cold Regions Research and Engineering Laboratory KW - East-Central Alaska KW - carbon KW - tunnels KW - buildings KW - Alaska KW - heterogeneity KW - construction KW - design KW - 30:Engineering geology KW - 20:Applied geophysics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/756293418?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=ERDC%2FCRREL+Technical+Report&rft.atitle=Opportune+Landing+Site+Program%3B+final+report&rft.au=Ryerson%2C+Charles+C%3BShoop%2C+Sally+A%3BKoenig%2C+George+G&rft.aulast=Ryerson&rft.aufirst=Charles&rft.date=2008-08-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=ERDC%2FCRREL+Technical+Report&rft.issn=&rft_id=info:doi/ L2 - http://www.eucop2010.no/ LA - English DB - GeoRef N1 - Conference title - Third European conference on Permafrost; EUCOP III N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2010-01-01 N1 - Document feature - illus. N1 - Last updated - 2012-06-07 N1 - CODEN - #07345 N1 - SubjectsTermNotLitGenreText - Alaska; Alaska Permafrost Research Center; buildings; carbon; construction; design; detection; East-Central Alaska; engineering properties; excavations; Fairbanks Alaska; geophysical methods; government agencies; heterogeneity; models; monitoring; permafrost; research; structures; tunnels; U. S. Army Cold Regions Research and Engineering Laboratory; U. S. Bureau of Mines; United States ER - TY - JOUR T1 - Proinflammatory Mediators of Toxic Shock and Their Correlation to Lethality AN - 754877874; 13367405 AB - Bacterial exotoxins and endotoxins both stimulate proinflammatory mediators but the contribution of each individual toxin in the release of mediators causing lethal shock is incompletely understood. This study examines the cytokine response and lethality of mice exposed to varying doses of staphylococcal enterotoxin B (SEB) or lipopolysaccharide (LPS) and their combinations. In vivo, SEB alone induced moderate levels of IL-2 and MCP-1 and all mice survived even with a high dose of SEB (100 kg/mouse). LPS (80 kg/mouse) caused 48% lethality and induced high levels of IL-6 and MCP-1. SEB induced low levels of TNFa, IL-1, IFNg, MIP-2, and LPS synergized with SEB in the expression of these cytokines and that of IL-6 and MCP-1. Importantly, the synergistic action of SEB and LPS resulted in lethal shock and hypothermia. ANOVA of cytokine levels by survival status of SEB-plus-LPS groups revealed significantly higher levels of TNFa, IL-6, MIP-2, and MCP-1 in nonsurvivors measured at 8 hours. Significantly higher levels of IFNg and IL-2 were observed at 21 hours in nonsurvivors of toxic shock compared to those in survivors. Overall, synergistic action of SEB and LPS resulted in higher and prolonged levels of these key cytokines leading to toxic shock. JF - Mediators of Inflammation AU - Krakauer, Teresa AU - Buckley, Marilyn J AU - Fisher, Diana AD - Integrated Toxicology Division U.S. Army Medical Research Institute of Infectious Diseases Fort Detrick MD 21702-5011 Y1 - 2010 PY - 2010 DA - 2010 PB - Hindawi Publishing Corporation, P.O. Box 3079 Cuyahoga Falls OH 44223 USA VL - 2010 KW - Microbiology Abstracts B: Bacteriology KW - Endotoxins KW - Lipopolysaccharides KW - J 02350:Immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754877874?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Mediators+of+Inflammation&rft.atitle=Proinflammatory+Mediators+of+Toxic+Shock+and+Their+Correlation+to+Lethality&rft.au=Krakauer%2C+Teresa%3BBuckley%2C+Marilyn+J%3BFisher%2C+Diana&rft.aulast=Krakauer&rft.aufirst=Teresa&rft.date=2010-01-01&rft.volume=2010&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Mediators+of+Inflammation&rft.issn=1466-1861&rft_id=info:doi/10.1155%2F2010%2F517594 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-09-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Lipopolysaccharides DO - http://dx.doi.org/10.1155/2010/517594 ER - TY - JOUR T1 - Evolution of the Probiotic Concept: From Conception to Validation and Acceptance in Medical Science AN - 754565138; 13398978 AB - Two pioneering achievements by Ilya Ilyich Metchnikoff were recorded in 1908. Most notable was his Nobel Prize in Medicine for discovering the innate cellular immune response to an infectious challenge. Of lesser note was his recommendation, "...to absorb large quantities of microbes, as a general belief is that microbes are harmful. This belief is erroneous. There are many useful microbes, amongst which the lactic bacilli have an honorable place." While his discovery of the inflammatory response was rapidly incorporated into our understanding of cellular immunity, his recommendation "to absorb large quantities of microbes," on the other hand, languished for decades in limbos of indifference, skepticism, and disbelief. The present chapter is a synopsis of salient discoveries made during the past 100 years, which gradually displaced these skepticisms, validated his concept of "useful microbes," and propelled his "lactic bacilli" into the mainstream of modern medical science, practice, and therapy. JF - Advances in Applied Microbiology AU - Dobrogosz, Walter J AU - Peacock, Trent J AU - Hassan, Hosni M AD - United States Army, Carl R. Darnall Medical Center, Fort Hood, Texas, USA, hosni_hassan@ncsu.edu Y1 - 2010 PY - 2010 DA - 2010 SP - 1 EP - 41 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands VL - 72 SN - 0065-2164, 0065-2164 KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology KW - Bacilli KW - A 01490:Miscellaneous KW - J 02350:Immunology KW - F 06910:Microorganisms & Parasites UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754565138?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Advances+in+Applied+Microbiology&rft.atitle=Evolution+of+the+Probiotic+Concept%3A+From+Conception+to+Validation+and+Acceptance+in+Medical+Science&rft.au=Dobrogosz%2C+Walter+J%3BPeacock%2C+Trent+J%3BHassan%2C+Hosni+M&rft.aulast=Dobrogosz&rft.aufirst=Walter&rft.date=2010-01-01&rft.volume=72&rft.issue=&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Advances+in+Applied+Microbiology&rft.issn=00652164&rft_id=info:doi/10.1016%2FS0065-2164%2810%2972001-3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2014-02-21 N1 - SubjectsTermNotLitGenreText - Bacilli DO - http://dx.doi.org/10.1016/S0065-2164(10)72001-3 ER - TY - JOUR T1 - Host Determinants of HIV-1 Control in African Americans AN - 754554290; 13314750 AB - We performed a whole-genome association study of human immunodeficiency virus type 1 (HIV-1) set point among a cohort of African Americans, and an intronic single-nucleotide polymorphism (SNP) in the HLA-B gene showed one of the strongest associations. We use a subset of patients to demonstrate that this SNP reflects the effect of the HLA-B*5703 allele, which shows a genome-wide statistically significant association with viral load set point. These analyses therefore confirm a member of the HLA-B*57 group of alleles as the most important common variant that influences viral load variation in African Americans, which is consistent with what has been observed for individuals of European ancestry, among whom the most important common variant is HLA-B*5701. JF - Journal of Infectious Diseases AU - Pelak, Kimberly AU - Goldstein, David B AU - Walley, Nicole M AU - Fellay, Jacques AU - Ge, Dongliang AU - Shianna, Kevin V AU - Gumbs, Curtis AU - Gao, Xiaojiang AU - Maia, Jessica M AU - Cronin, Kenneth D AU - Hussain, Shehnaz K AU - Carrington, Mary AU - Michael, Nelson L AU - Weintrob, Amy C AD - Center for Human Genome Variation, Duke University Medical School, Durham, North Carolina, amy.weintrob@us.army.mil Y1 - 2010///0, PY - 2010 DA - 0, 2010 SP - 1141 EP - 1149 PB - University of Chicago Press, P.O. Box 37005 Chicago IL 60637 USA, [mailto:help@press.uchicago.edu], [URL:http://www.journals.uchicago.edu/] VL - 201 IS - 8 SN - 0022-1899, 0022-1899 KW - Genetics Abstracts; Virology & AIDS Abstracts; Health & Safety Science Abstracts; Immunology Abstracts KW - Histocompatibility antigen HLA KW - Single-nucleotide polymorphism KW - Human immunodeficiency virus 1 KW - Statistical analysis KW - Ethnic groups KW - H 6000:Natural Disasters/Civil Defense/Emergency Management KW - V 22360:AIDS and HIV KW - G 07880:Human Genetics KW - F 06910:Microorganisms & Parasites UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754554290?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Host+Determinants+of+HIV-1+Control+in+African+Americans&rft.au=Pelak%2C+Kimberly%3BGoldstein%2C+David+B%3BWalley%2C+Nicole+M%3BFellay%2C+Jacques%3BGe%2C+Dongliang%3BShianna%2C+Kevin+V%3BGumbs%2C+Curtis%3BGao%2C+Xiaojiang%3BMaia%2C+Jessica+M%3BCronin%2C+Kenneth+D%3BHussain%2C+Shehnaz+K%3BCarrington%2C+Mary%3BMichael%2C+Nelson+L%3BWeintrob%2C+Amy+C&rft.aulast=Pelak&rft.aufirst=Kimberly&rft.date=2010-01-01&rft.volume=201&rft.issue=8&rft.spage=1141&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1086%2F651382 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Histocompatibility antigen HLA; Single-nucleotide polymorphism; Statistical analysis; Ethnic groups; Human immunodeficiency virus 1 DO - http://dx.doi.org/10.1086/651382 ER - TY - JOUR T1 - Internal coating of zirconia restoration with silica-based ceramic improves bonding of resin cement to dental zirconia ceramic AN - 753677515; 13240598 AB - Resin bonding to zirconia ceramic cannot be established by standard methods that are utilized for conventional silica-based dental ceramics. This study was aimed to examine the tensile bond strength of resin cement to zirconia ceramic using a new laboratory technique. Sixty-four zirconia ceramic specimens were air-abraded using Al2O3 particles and divided into two groups; the control group with no pretreatment (Control), and the group pretreated using the internal coating technique (INT), in which the surface of the zirconia specimens were thinly coated by fusing silica-based ceramic and air-abraded in the same manner. The specimens in each group were further divided into two subgroups according to the silane coupling agents applied; a mixture of dentin primer/silane coupling agent (Clearfil SE Bond Primer/Porcelain Bond Activator) or a newly developed single-component silane coupling agent (Clearfil Ceramic Primer). After bonding with dual-cured resin cement (Panavia F 2.0), they were stored in water for 24 h and half of them were additionally subjected to thermal cycling. The tensile bond strengths were tested using a universal testing machine. ANOVAs revealed significant influence of ceramic surface pretreatment (p0.001), silane coupling agent (p0.001) and thermal cycling (p0.001); the INT coating technique significantly increased the bond strengths of resin cement to zirconia ceramic, whereas thermal cycling significantly decreased the bond strengths. The use of a single-component silane coupling agent demonstrated significantly higher bond strengths than that of a mixture of dentin primer/silane coupling agent. The internal coating of zirconia dental restorations with silica-based ceramic followed by silanization may be indicated in order to achieve better bonding for the clinical success. JF - Bio-Medical Materials and Engineering AU - Kitayama, Shuzo AU - Tagami, Junji AD - The Global Center of Excellence (GCOE) Program, International Research Center for Molecular Science in Tooth and Bone Diseases, Tokyo Medical and Dental University, Tokyo, Japan Y1 - 2010 PY - 2010 DA - 2010 SP - 77 EP - 87 PB - IOS Press, 5795-G Burke Centre Pkwy Burke VA 22015 USA VL - 20 IS - 2 SN - 0959-2989, 0959-2989 KW - Biotechnology and Bioengineering Abstracts KW - Zirconia ceramic KW - resin cement KW - internal coating technique KW - silica-based ceramic KW - silane coupling agent KW - thermal cycling KW - Ceramics KW - Dental restorative materials KW - Dentin KW - Resins KW - Cement KW - Primers KW - zirconia KW - Coatings KW - W 30920:Tissue Engineering UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/753677515?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Bio-Medical+Materials+and+Engineering&rft.atitle=Internal+coating+of+zirconia+restoration+with+silica-based+ceramic+improves+bonding+of+resin+cement+to+dental+zirconia+ceramic&rft.au=Kitayama%2C+Shuzo%3BTagami%2C+Junji&rft.aulast=Kitayama&rft.aufirst=Shuzo&rft.date=2010-01-01&rft.volume=20&rft.issue=2&rft.spage=77&rft.isbn=&rft.btitle=&rft.title=Bio-Medical+Materials+and+Engineering&rft.issn=09592989&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Ceramics; Dentin; Dental restorative materials; Resins; Cement; Primers; zirconia; Coatings ER - TY - JOUR T1 - Demographics of More than 12,000 Individuals of a Keystone Species in the Northern Sonoran Desert since the Mid-1800s AN - 746152983; 12845337 AB - We studied a cohort-based, long-lived species to determine whether favorable periods that promote regeneration are driven by local, regional, or global-scale factors. Limited demographic data exist for the keystone species Carnegiea gigantea over its range. We obtained a data set collected for 12,232 plants over an area of more than 11 km super(2) at a restricted military zone, located far from any other studied population. We developed the establishment pattern for the species over the last 200 yr and compared population growth trends with those for other sites and with global-scale volcanism, which has been previously linked to the regeneration of the species. This population was significantly related to the two closer sites, suggesting a regional influence in regeneration and cohort establishment. Other eastern sites like ours also exhibited a regeneration peak in the 1920s. This population was not significantly related to volcanic eruptions, as has been documented elsewhere, though this may be due to subsequent mortality at the site, which would have effectively erased the record of establishment in past periods. Unlike past work, our study goes beyond a single population. We synthesized data from other known populations in order to produce, for the first time, a coherent picture of the patterns of regeneration over much of the species' range. Large-scale climatic (e.g., unusually rainy periods) and geologic (global-scale volcanism) events promote the establishment of cohorts during the same time periods historically, though to differing extents in different populations: hot, western populations have particularly large cohorts in response to volcanism, while more eastern sites may have observable cohorts during known wetter periods. Thus, these different large-scale phenomena appear to be of varying significance in a population on the basis of the population's location and associated environment. This provides insight into global climate change impacts on the species, whose keystone status will ultimately affect the success of and changes in the entire biome. JF - International Journal of Plant Sciences AU - Danzer, Shelley AU - Drezner, Taly Dawn AD - Arizona Army National Guard, 5636 East McDowell Road, Phoenix, Arizona 85008, U.S.A., drezner@yorku.ca Y1 - 2010 PY - 2010 DA - 2010 SP - 538 EP - 546 PB - University of Chicago Press, P.O. Box 37005 Chicago IL 60637 USA, [mailto:help@press.uchicago.edu], [URL:http://www.journals.uchicago.edu/] VL - 171 IS - 5 SN - 1058-5893, 1058-5893 KW - Ecology Abstracts; Sustainability Science Abstracts KW - Arizona KW - Carnegiea gigantea KW - plant KW - climate interactions KW - saguaro cactus KW - volcanism. KW - demography KW - Historical account KW - Mortality KW - Data processing KW - Eruptions KW - regeneration KW - Population growth KW - Climatic changes KW - Volcanoes KW - Population studies KW - USA, Arizona, Sonoran Desert KW - Demography KW - Keystone species KW - Deserts KW - population growth KW - Geology KW - Military KW - keystone species KW - M3 1010:Issues in Sustainable Development KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/746152983?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+Plant+Sciences&rft.atitle=Demographics+of+More+than+12%2C000+Individuals+of+a+Keystone+Species+in+the+Northern+Sonoran+Desert+since+the+Mid-1800s&rft.au=Danzer%2C+Shelley%3BDrezner%2C+Taly+Dawn&rft.aulast=Danzer&rft.aufirst=Shelley&rft.date=2010-01-01&rft.volume=171&rft.issue=5&rft.spage=538&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+Plant+Sciences&rft.issn=10585893&rft_id=info:doi/10.1086%2F652013 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Keystone species; Demography; Mortality; Eruptions; Data processing; Deserts; Population growth; Climatic changes; Population studies; demography; Historical account; regeneration; population growth; Volcanoes; Geology; Military; keystone species; Carnegiea gigantea; USA, Arizona, Sonoran Desert DO - http://dx.doi.org/10.1086/652013 ER - TY - JOUR T1 - Natural History of Colonization with Gram-Negative Multidrug-Resistant Organisms among Hospitalized Patients AN - 745978126; 12845242 AB - Objective. To determine the anatomic sites and natural history of colonization with gram-negative multidrug-resistant organisms (MDROs). Design. Prospective, longitudinal cohort study. Setting. Walter Reed Army Medical Center, a 236-bed tertiary care center in Washington, DC. Patients. Deployed subjects (ie, inpatients medically evacuated from Iraq or Afghanistan) or nondeployed subjects admitted to the same hospital. Methods. Consenting patients had 6 anatomic sites cultured every 3 days for 2 weeks and then weekly. Gram-negative organisms resistant to 3 or more classes of antibiotics were considered MDROs. Isolates were genotyped using pulsed-field gel electrophoresis. Clinical data, data on antibiotic use, and clinical culture results were collected. Results. Of 60 deployed subjects, 14 (23%) were colonized with an MDRO at admission, and 13 (22%) had incident colonization during hospitalization. The groin was the most sensitive anatomic site for detecting MDRO colonization, and all but one subject remained colonized for the duration of their hospitalization. Sixty percent of subjects with incident Acinetobacter colonization and 25% of subjects with incident Klebsiella colonization had strains that were related to those isolated from other subjects. Of 60 nondeployed subjects, 5 (8%) were colonized with an MDRO at admission; all had recent healthcare contact, and 1 nondeployed subject had an isolate related to a strain recovered from a deployed subject. Conclusions. Colonization with gram-negative MDROs is common among patients with war-related trauma admitted to a military hospital and also occurs among nondeployed patients with recent healthcare contact. The groin is the most sensitive anatomic site for active surveillance, and spontaneous decolonization is rare. JF - Infection Control and Hospital Epidemiology AU - Weintrob, Amy C AU - Roediger, Mollie P AU - Barber, Melissa AU - Summers, Amy AU - Fieberg, Ann M AU - Dunn, James AU - Seldon, Venus AU - Leach, Fluryanne AU - Huang, Xiao-Zhe AU - Nikolich, Mikeljon P AU - Wortmann, Glenn W AD - Uniformed Services University of the Health Sciences, Infectious Disease Clinical Research Program, Bethesda, and the Walter Reed Army Institute of Research, Silver Spring, Maryland, Amy.Weintrob@us.army.mil Y1 - 2010 PY - 2010 DA - 2010 SP - 330 EP - 337 PB - University of Chicago Press, P.O. Box 37005 Chicago IL 60637 USA, [mailto:help@press.uchicago.edu], [URL:http://www.journals.uchicago.edu/] VL - 31 IS - 4 SN - 0899-823X, 0899-823X KW - Microbiology Abstracts B: Bacteriology KW - Klebsiella KW - Colonization KW - Acinetobacter KW - Data processing KW - Drug resistance KW - Pulsed-field gel electrophoresis KW - Antibiotics KW - Hospitals KW - Trauma KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745978126?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Infection+Control+and+Hospital+Epidemiology&rft.atitle=Natural+History+of+Colonization+with+Gram-Negative+Multidrug-Resistant+Organisms+among+Hospitalized+Patients&rft.au=Weintrob%2C+Amy+C%3BRoediger%2C+Mollie+P%3BBarber%2C+Melissa%3BSummers%2C+Amy%3BFieberg%2C+Ann+M%3BDunn%2C+James%3BSeldon%2C+Venus%3BLeach%2C+Fluryanne%3BHuang%2C+Xiao-Zhe%3BNikolich%2C+Mikeljon+P%3BWortmann%2C+Glenn+W&rft.aulast=Weintrob&rft.aufirst=Amy&rft.date=2010-01-01&rft.volume=31&rft.issue=4&rft.spage=330&rft.isbn=&rft.btitle=&rft.title=Infection+Control+and+Hospital+Epidemiology&rft.issn=0899823X&rft_id=info:doi/10.1086%2F651304 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Colonization; Data processing; Drug resistance; Pulsed-field gel electrophoresis; Antibiotics; Trauma; Hospitals; Klebsiella; Acinetobacter DO - http://dx.doi.org/10.1086/651304 ER - TY - JOUR T1 - Development of Cell-Based Assays to Measure Botulinum Neurotoxin Serotype A Activity Using Cleavage-Sensitive Antibodies AN - 745711373; 13131908 AB - Botulinum neurotoxins (BoNTs) are zinc-metalloproteases that cleave components of the SNARE (soluble N-ethylmaleimidesensitive factor attachment protein receptor) protein complex, inhibiting acetylcholine release into neuromuscular junctions, resulting in flaccid paralysis and eventual death. The potential for the malicious misuse of these toxins as bioweapons has created an urgent need to develop effective therapeutic countermeasures. Robust cell-based assays will be essential for lead identification and the optimization of therapeutic candidates. In this study, the authors developed novel BoNT serotype A (BoNT/A) cleavage-sensitive (BACS) antibodies that only interact with full-length SNAP-25 (synaptosomal-associated protein of 25 kDa), the molecular target of the BoNT/A serotype. These antibodies exhibit high specificity for full-length SNAP-25, allowing the BoNT/A-mediated proteolysis of this protein to be measured in diverse assay formats, including several variations of enzyme-linked immunosorbent assay and multiple immunofluorescence methods. Assays built around the BACS antibodies displayed excellent sensitivity, had excellent reproducibility, and were amenable to multiwell formats. Importantly, these assays provided novel methods for evaluating BoNT/A activity in cellular models of intoxication and allowed for the high-throughput evaluation of experimental compounds. JF - Journal of Biomolecular Screening AU - Nuss, Jonathan E AU - Ruthel, Gordon AU - Tressler, Lyal E AU - Wanner, Laura M AU - Torres-Melendez, Edna AU - Hale, Martha L AU - Bavari, Sina AD - US Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, sina.bavari@amedd.army.mil Y1 - 2010/01// PY - 2010 DA - Jan 2010 SP - 42 EP - 51 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU UK VL - 15 IS - 1 SN - 1087-0571, 1087-0571 KW - CSA Neurosciences Abstracts; Biotechnology and Bioengineering Abstracts KW - Proteolysis KW - Intoxication KW - Enzyme-linked immunosorbent assay KW - Serotypes KW - Immunofluorescence KW - Botulinum toxin type A KW - SNAP receptors KW - Paralysis KW - Bacterial artificial chromosomes KW - Antibodies KW - SNAP-25 protein KW - Neuromuscular junctions KW - Acetylcholine KW - Botulinum toxin KW - W 30935:Food Biotechnology KW - N3 11145:Methodology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745711373?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Biomolecular+Screening&rft.atitle=Development+of+Cell-Based+Assays+to+Measure+Botulinum+Neurotoxin+Serotype+A+Activity+Using+Cleavage-Sensitive+Antibodies&rft.au=Nuss%2C+Jonathan+E%3BRuthel%2C+Gordon%3BTressler%2C+Lyal+E%3BWanner%2C+Laura+M%3BTorres-Melendez%2C+Edna%3BHale%2C+Martha+L%3BBavari%2C+Sina&rft.aulast=Nuss&rft.aufirst=Jonathan&rft.date=2010-01-01&rft.volume=15&rft.issue=1&rft.spage=42&rft.isbn=&rft.btitle=&rft.title=Journal+of+Biomolecular+Screening&rft.issn=10870571&rft_id=info:doi/10.1177%2F1087057109354779 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-07-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Intoxication; Proteolysis; Enzyme-linked immunosorbent assay; Serotypes; Botulinum toxin type A; Immunofluorescence; SNAP receptors; Bacterial artificial chromosomes; Paralysis; Antibodies; SNAP-25 protein; Neuromuscular junctions; Acetylcholine; Botulinum toxin DO - http://dx.doi.org/10.1177/1087057109354779 ER - TY - JOUR T1 - Frequency of extreme storms based on beach erosion at Northern Assateague Island, Maryland AN - 744618324; 12912733 AB - This paper examines morphologic response to storms at northern Assateague Island, MD. Time series of hindcast waves and water level were input to drive the SBEACH beach erosion and overwash numerical model to estimate beach response, groundtruthed by documentation and available evidence of storms that caused significant morphologic change at the site. The analysis proceeded through application of the generalized Pareto distribution, with tropical and extratropical storms treated as separate populations. Five storm-related parameters were examined and correlated with volume of beach erosion: peak surge, peak water level (surge plus tide), storm duration, and two new parameters called the integrated hydrograph and the integrated significant wave height, "integrated" referring to the product of time and water level or wave height above a threshold. Storm-induced erosion was found to be only weakly correlated or not correlated with the individual parameters of peak storm surge and peak water level. For tropical storms, erosion is strongly correlated with integrated wave height, and to a lesser extent with storm duration and integrated hydrograph, whereas for extratropical storms, erosion is found to be significantly correlated with the integrated hydrograph and to a lesser extent with integrated wave height and storm duration. JF - Shore & Beach AU - Munger, S AU - Kraus, N C AD - U.S. Army Engineer Research and Development Center, Coastal and Hydraulics Laboratory, 3909 Halls Ferry Road, Vicksburg, MS 39180, USA Y1 - 2010///0, PY - 2010 DA - 0, 2010 SP - 3 EP - 11 VL - 78 IS - 2 SN - 0037-4237, 0037-4237 KW - Aqualine Abstracts; Water Resources Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Oceanic Abstracts; Meteorological & Geoastrophysical Abstracts; Environment Abstracts KW - shores KW - Hydrograph analysis KW - Shores KW - Time series analysis KW - Storms KW - Water levels KW - Islands KW - Numerical models KW - Hydrographs KW - Extratropical cyclones KW - Marine KW - Beaches KW - Mathematical models KW - time series analysis KW - Surges KW - Wave processes on beaches KW - Brackish KW - Beach Erosion KW - Water Level KW - Significant wave height KW - ANW, USA, Maryland KW - Tides KW - Wave Height KW - Erosion KW - water levels KW - Storm surges KW - Wave hindcasting KW - Wave height KW - Beach erosion KW - AQ 00007:Industrial Effluents KW - Q2 09271:Coastal morphology KW - SW 0870:Erosion and sedimentation KW - O 3050:Sediment Dynamics KW - M2 556.16:Runoff (556.16) KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/744618324?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Shore+%26+Beach&rft.atitle=Frequency+of+extreme+storms+based+on+beach+erosion+at+Northern+Assateague+Island%2C+Maryland&rft.au=Munger%2C+S%3BKraus%2C+N+C&rft.aulast=Munger&rft.aufirst=S&rft.date=2010-01-01&rft.volume=78&rft.issue=2&rft.spage=3&rft.isbn=&rft.btitle=&rft.title=Shore+%26+Beach&rft.issn=00374237&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-06-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Water levels; Mathematical models; Storm surges; Wave hindcasting; Wave height; Wave processes on beaches; Significant wave height; Beach erosion; Hydrograph analysis; Erosion; Numerical models; Time series analysis; Storms; Extratropical cyclones; shores; Beaches; Islands; water levels; time series analysis; Tides; Surges; Shores; Hydrographs; Beach Erosion; Water Level; Wave Height; ANW, USA, Maryland; Brackish; Marine ER - TY - JOUR T1 - Success in Kashmir: a positive trend in civil-military integration during humanitarian assistance operations AN - 743807205; 3976164 AB - The modern cast of disaster relief actors includes host nations, non-governmental organisations, private volunteer organisations, military organisations and others. Each group, civilian or military, has valuable skills and experiences critical to disaster relief work. The goal of this paper is to supplement the study of civil-military relief efforts with contemporary anecdotal experience. The paper examines the interaction between US military forces and other disaster relief actors during the 2005 Kashmir earthquake relief effort. The author uses direct observations made while working in Pakistan to contrast the relationships and activities from that effort with other accounts in prevailing scholarly disaster literature and military doctrine. Finally, this paper suggests that the Kashmir model of integration, coordination and transparency of intent creates a framework in which future humanitarian assistance operations could be successfully executed. Recommendations to improve civil-military interaction in future relief efforts will also be addressed. Reprinted by permission of Blackwell Publishers JF - Disasters AU - Thompson, Wiley C AD - United States Military Academy Y1 - 2010/01// PY - 2010 DA - Jan 2010 SP - 1 EP - 15 VL - 34 IS - 1 SN - 0361-3666, 0361-3666 KW - Anthropology KW - Kashmir KW - Earthquakes KW - Disaster relief KW - Pakistan KW - Humanitarianism KW - Non-governmental organizations KW - Civil-military relations KW - Disasters UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/743807205?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Disasters&rft.atitle=Success+in+Kashmir%3A+a+positive+trend+in+civil-military+integration+during+humanitarian+assistance+operations&rft.au=Thompson%2C+Wiley+C&rft.aulast=Thompson&rft.aufirst=Wiley&rft.date=2010-01-01&rft.volume=34&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Disasters&rft.issn=03613666&rft_id=info:doi/10.1111%2Fj.0361-3666.2009.01111.x LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 3601; 3599 3601; 6119 9680; 2316 8050; 8708 9030; 3836 8559 3601; 318 387 30 DO - http://dx.doi.org/10.1111/j.0361-3666.2009.01111.x ER - TY - JOUR T1 - Modeling and analysis of the response of a triaxial, frequency-domain electromagnetic induction sensor to a buried linear conductor AN - 742915852; 2010-041863 AB - This paper presents analytical modeling results for a triaxial frequency-domain electromagnetic-induction (EMI) sensor over a homogeneous earth containing a long linear conductor. Although the conductor studied is intended to represent an underground wire or pipe, it can represent any subsurface, linear geologic structure that can channel current. Treating the sensor transmitter as a vertical magnetic dipole, the model combines the well-known solution for the magnetic field arising from the interaction with the earth with the solution for the induced magnetic field from the excited subsurface conductor. Expressions for the three components of the magnetic field at an arbitrary point above the earth are presented. Two types of coupled, moving transmitter-receiver configurations (coaxial and coplanar) were considered, and the model is sufficiently flexible to allow for many other sensor variations to be studied. Characteristics of the sensor signals were explored through several parametric modeling studies that demonstrate the sensitivity of the signals to transmitter frequency, earth conductivity, conductor depth, sensor geometry, and crossing angle. Using simple relationships developed from analysis of the sensor signals, key parameters such as conductor depth and orientation can be estimated. The ability of the model to predict and characterize sensor output should prove helpful in distinguishing between geologic features and man-made underground infrastructure. These modeling results also are expected to facilitate frequency-domain EMI data analysis and interpretation, sensor design and operation, and the development of detection and classification algorithms. JF - Geophysics AU - McKenna, Sean P AU - McKenna, Jason R Y1 - 2010/01// PY - 2010 DA - January 2010 SP - F1 EP - F14 PB - Society of Exploration Geophysicists, Tulsa, OK VL - 75 IS - 1 SN - 0016-8033, 0016-8033 KW - electrical conductivity KW - apparent resistivity KW - numerical models KW - data acquisition KW - geophysical methods KW - data processing KW - mathematical models KW - magnetic field KW - frequency domain analysis KW - theoretical studies KW - electromagnetic methods KW - algorithms KW - 20:Applied geophysics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742915852?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Geophysics&rft.atitle=Modeling+and+analysis+of+the+response+of+a+triaxial%2C+frequency-domain+electromagnetic+induction+sensor+to+a+buried+linear+conductor&rft.au=McKenna%2C+Sean+P%3BMcKenna%2C+Jason+R&rft.aulast=McKenna&rft.aufirst=Sean&rft.date=2010-01-01&rft.volume=75&rft.issue=1&rft.spage=F1&rft.isbn=&rft.btitle=&rft.title=Geophysics&rft.issn=00168033&rft_id=info:doi/10.1190%2F1.3267876 L2 - http://library.seg.org/journal/gpysa7 LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2013, American Geosciences Institute. Reference includes data supplied by Society of Exploration Geophysicists, Tulsa, OK, United States N1 - Date revised - 2010-01-01 N1 - Number of references - 33 N1 - PubXState - OK N1 - Document feature - illus. incl. 1 table N1 - SuppNotes - Includes appendices N1 - Last updated - 2013-05-16 N1 - CODEN - GPYSA7 N1 - SubjectsTermNotLitGenreText - algorithms; apparent resistivity; data acquisition; data processing; electrical conductivity; electromagnetic methods; frequency domain analysis; geophysical methods; magnetic field; mathematical models; numerical models; theoretical studies DO - http://dx.doi.org/10.1190/1.3267876 ER - TY - JOUR T1 - Mild traumatic brain injury (concussion) during combat: lack of association of blast mechanism with persistent postconcussive symptoms. AN - 742781133; pmid-20051900 AB - OBJECTIVE: To determine whether screening for a blast mechanism of concussion identifies individuals at higher risk of persistent postconcussive symptoms (PCS). SETTING: United States Army post. PARTICIPANTS: 3952 US Army infantry soldiers were administered anonymous surveys 3 to 6 months after returning from a yearlong deployment to Iraq. MAIN OUTCOME MEASURES: Self-reported concussion (defined as an injury that resulted in being "dazed, confused, or 'seeing stars'"; "not remembering the injury"; or "losing consciousness [knocked out]): Patient Health Questionnaire 15-item scale for physical symptoms and PCS; Posttraumatic Stress Disorder Checklist; and Patient Health Questionnaire depression module. RESULTS: Of the 587 soldiers (14.9% of the total sample) who met criteria for concussion, 201 (34.2%) reported loss of consciousness, and 373 (63.5%) reported only an alteration of consciousness without loss of consciousness; 424 (72.2%) reported a blast mechanism, and 150 (25.6%) reported a nonblast mechanism. Among soldiers who lost consciousness, blast mechanism was significantly associated with headaches and tinnitus 3 to 6 months postdeployment compared with a nonblast mechanism. However, among the larger group of soldiers reporting concussions without loss of consciousness, blast was not associated with adverse health outcomes. CONCLUSIONS: Blast mechanism of concussion was inconsistently associated with PCS, depending on the definition of concussion utilized. A self-reported history of blast mechanism was not associated with persistent PCS for the majority of US soldiers with concussions. JF - The Journal of head trauma rehabilitation AU - Wilk, Joshua E AU - Thomas, Jeffrey L AU - McGurk, Dennis M AU - Riviere, Lyndon A AU - Castro, Carl A AU - Hoge, Charles W AD - Division of Psychiatry and Neuroscience, Walter Reed Army Institute of Research, US Army Medical Research and Materiel Command, Silver Spring, Maryland 20910, USA. joshua.wilk@amedd.army.mil Y1 - 2010/01// PY - 2010 DA - Jan 2010 SP - 9 EP - 14 VL - 25 IS - 1 SN - 0885-9701, 0885-9701 KW - Index Medicus KW - National Library of Medicine KW - Depressive Disorder, Major -- diagnosis KW - Post-Concussion Syndrome -- epidemiology KW - Questionnaires KW - Humans KW - Brain Concussion -- diagnosis KW - Blast Injuries -- diagnosis KW - Neurologic Examination KW - Blast Injuries -- epidemiology KW - Depressive Disorder, Major -- epidemiology KW - Combat Disorders -- epidemiology KW - Mass Screening KW - Cross-Sectional Studies KW - Post-Concussion Syndrome -- diagnosis KW - Risk Factors KW - Health Surveys KW - Brain Concussion -- epidemiology KW - Combat Disorders -- diagnosis KW - Unconsciousness -- epidemiology KW - Incidence KW - Follow-Up Studies KW - Statistics as Topic KW - Male KW - Consciousness Disorders -- epidemiology KW - Military Personnel KW - Iraq War, 2003 - UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742781133?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+head+trauma+rehabilitation&rft.atitle=Mild+traumatic+brain+injury+%28concussion%29+during+combat%3A+lack+of+association+of+blast+mechanism+with+persistent+postconcussive+symptoms.&rft.au=Wilk%2C+Joshua+E%3BThomas%2C+Jeffrey+L%3BMcGurk%2C+Dennis+M%3BRiviere%2C+Lyndon+A%3BCastro%2C+Carl+A%3BHoge%2C+Charles+W&rft.aulast=Wilk&rft.aufirst=Joshua&rft.date=2010-01-01&rft.volume=25&rft.issue=1&rft.spage=9&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+head+trauma+rehabilitation&rft.issn=08859701&rft_id=info:doi/ LA - English (eng) DB - ComDisDome N1 - Date revised - 2010-04-13 N1 - Last updated - 2010-09-25 ER - TY - JOUR T1 - Neurochemical and electrophysiological diagnosis of reversible neurotoxicity in earthworms exposed to sublethal concentrations of CL-20. AN - 734220937; 19274471 AB - Hexanitrohexaazaisowurtzitane (CL-20) is a relatively new energetic compound sharing some degree of structural similarity with hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), a known neurotoxic compound. Previously, we demonstrated using a noninvasive electrophysiological technique that CL-20 was a more potent neurotoxicant than RDX to the earthworm Eisenia fetida. In the present study, we investigated the effect of CL-20 exposure and subsequent recovery on muscarinic acetylcholine receptors (mAChRs) to further define the mechanism of reversible neurotoxicity of CL-20 in E. fetida. We used a noninvasive electrophysiological technique to evaluate neurotoxicity in CL-20-treated worms, and then measured how such exposures altered levels of whole-body mAChR in the same animals. A good correlation exists between these two types of endpoints. Effect on mAChR levels was most prominent at day 6 of exposure. After 7 days of recovery, both conduction velocity and mAChR were significantly restored. Our results show that sublethal concentrations of CL-20 significantly reduced mAChR levels in a concentration- and duration-dependent manner, which was accompanied with significant decreases in the conduction velocity of the medial and lateral giant nerve fibers. After 7-day post exposure recovery, worms restored both neurochemical (mAChR) and neurophysiological (conduction velocity) endpoints that were reduced during 6-day exposures to CL-20 concentrations from 0.02 to 0.22 microg/cm(2). Our findings support the idea that CL-20 induced neurotoxic effects are reversible, and suggest that CL-20 neurotoxicity may be mediated through the cholinergic system. Future studies will investigate other neurotransmission systems such as GABA, glutamate, and monoamine. Ion channels in the nerve membrane should be examined to further define the precise mechanisms underlying CL-20 neurotoxicity. JF - Environmental science and pollution research international AU - Gong, Ping AU - Basu, Niladri AU - Scheuhammer, Anton M AU - Perkins, Edward J AD - SpecPro Inc., 3909 Halls Ferry Road, Vicksburg, MS 39180, USA. ping.gong@us.army.mil Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 181 EP - 186 VL - 17 IS - 1 KW - 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaaza-isowurtzitane KW - 0 KW - Aza Compounds KW - Biogenic Monoamines KW - Explosive Agents KW - Heterocyclic Compounds KW - Neurotoxins KW - Receptor, Muscarinic M3 KW - Glutamic Acid KW - 3KX376GY7L KW - gamma-Aminobutyric Acid KW - 56-12-2 KW - Index Medicus KW - Neurotoxicity Syndromes -- diagnosis KW - Animals KW - Glutamic Acid -- metabolism KW - Dose-Response Relationship, Drug KW - Toxicity Tests KW - Lethal Dose 50 KW - Neurotoxicity Syndromes -- physiopathology KW - Receptor, Muscarinic M3 -- metabolism KW - gamma-Aminobutyric Acid -- metabolism KW - Time Factors KW - Biogenic Monoamines -- metabolism KW - Oligochaeta -- growth & development KW - Heterocyclic Compounds -- metabolism KW - Oligochaeta -- metabolism KW - Neurotoxins -- metabolism KW - Oligochaeta -- drug effects KW - Explosive Agents -- toxicity KW - Electrophysiology -- methods KW - Aza Compounds -- metabolism KW - Heterocyclic Compounds -- toxicity KW - Explosive Agents -- metabolism KW - Environmental Exposure -- adverse effects KW - Aza Compounds -- toxicity KW - Neurotoxins -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/734220937?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+science+and+pollution+research+international&rft.atitle=Neurochemical+and+electrophysiological+diagnosis+of+reversible+neurotoxicity+in+earthworms+exposed+to+sublethal+concentrations+of+CL-20.&rft.au=Gong%2C+Ping%3BBasu%2C+Niladri%3BScheuhammer%2C+Anton+M%3BPerkins%2C+Edward+J&rft.aulast=Gong&rft.aufirst=Ping&rft.date=2010-01-01&rft.volume=17&rft.issue=1&rft.spage=181&rft.isbn=&rft.btitle=&rft.title=Environmental+science+and+pollution+research+international&rft.issn=1614-7499&rft_id=info:doi/10.1007%2Fs11356-009-0117-5 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-02-22 N1 - Date created - 2010-01-05 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: J Neurocytol. 2001 Apr;30(4):313-25 [11875279] Cell Mol Life Sci. 2002 Mar;59(3):527-39 [11964130] Eur J Neurosci. 2003 Jan;17(1):119-27 [12534975] J Exp Zool A Comp Exp Biol. 2003 Mar 1;296(1):18-29 [12589687] Neuroscience. 2003;121(2):473-8 [14522005] J Environ Sci Health B. 1983;18(1):65-88 [6339601] Trends Neurosci. 1995 Feb;18(2):104-11 [7537401] Crit Rev Neurobiol. 1996;10(1):69-99 [8853955] Hum Exp Toxicol. 1996 Mar;15 Suppl 1:S20-35 [8882557] J Toxicol Environ Health A. 2005 Aug 27;68(16):1413-29 [16009654] J Environ Qual. 2005 Nov-Dec;34(6):2208-16 [16275722] Cell Metab. 2006 Apr;3(4):237-45 [16581001] Toxicol Sci. 2006 May;91(1):202-9 [16446290] Pharmacol Ther. 2006 Jul;111(1):174-93 [16324748] Clin Toxicol (Phila). 2007 Jun-Aug;45(5):454-7 [17503243] Environ Toxicol Chem. 2007 May;26(5):954-9 [17521142] Environ Toxicol Chem. 2007 Jul;26(7):1481-7 [17665690] Environ Toxicol Chem. 2007 Sep;26(9):1963-7 [17705658] Front Biosci. 2008;13:1240-9 [17981626] WormBook. 2006;:1-29 [18050433] WormBook. 2007;:1-21 [18050502] Sci Total Environ. 2008 Feb 1;390(1):295-9 [17996277] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1007/s11356-009-0117-5 ER - TY - JOUR T1 - Suberoylanilide hydroxamic acid (SAHA) potentiates paclitaxel-induced apoptosis in ovarian cancer cell lines. AN - 734175123; 19875160 AB - To determine if SAHA, a histone deacetylase inhibitor, decreases ovarian cancer cell viability when combined with paclitaxel in vitro, and to explore molecular alterations of combined paclitaxel+SAHA treatment. SKOV3 and Hey ovarian cancer cell lines were treated for 24 h with paclitaxel, then re-treated with SAHA or paclitaxel for an additional 48 h. Protein extracts were prepared at 48 h for western blot analysis. Cell viability was assessed at 72 h using the ApoAlert Annexin V Apoptosis Kit. SAHA causes G1 and G2 cell cycle arrest in ovarian cancer cell lines. Cell viability was significantly reduced by combined paclitaxel+SAHA treatment. In Hey cells, viability was reduced to 67% with paclitaxel, and to 48% with paclitaxel+SAHA (p<0.001). In the SKOV3 cell line, viability was reduced to 70% with continuous paclitaxel treatment, and was further reduced to 57% in the combined treatment group (p<0.05). Increased PARP cleavage was noted in the paclitaxel+SAHA groups. SAHA increased expression of p21cip1/waf1 and p27Kip1, down regulated cyclins A and B, and suppressed CDK1. Paclitaxel induced expression of survivin, an inhibitor of apoptosis protein, was reduced to baseline control levels with the addition of SAHA. The pro-apoptotic protein, Bad, was also increased with SAHA. Paclitaxel+SAHA reduces cell viability in excess of either agent alone in ovarian cancer cell lines. Cell death is mediated via several mechanisms including G1/G2 arrest from CDK1 downregulation, inhibition of paclitaxel-induced survivin accumulation, and from increased Bad expression. JF - Gynecologic oncology AU - Dietrich, Charles S AU - Greenberg, Victoria L AU - DeSimone, Christopher P AU - Modesitt, Susan C AU - van Nagell, John R AU - Craven, Rolf AU - Zimmer, Stephen G AD - Gynecologic Oncology Service, Department of Obstetrics and Gynecology, Tripler Army Medical Center, 1 Jarrett White Road, Honolulu, HI 96859-5000, USA. chuck.dietrich@us.army.mil Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 126 EP - 130 VL - 116 IS - 1 KW - Cyclin B KW - 0 KW - Hydroxamic Acids KW - vorinostat KW - 58IFB293JI KW - CDC2 Protein Kinase KW - EC 2.7.11.22 KW - Paclitaxel KW - P88XT4IS4D KW - Index Medicus KW - Cell Survival -- drug effects KW - CDC2 Protein Kinase -- antagonists & inhibitors KW - Humans KW - CDC2 Protein Kinase -- biosynthesis KW - Cyclin B -- biosynthesis KW - Cyclin B -- antagonists & inhibitors KW - Cell Line, Tumor KW - Drug Synergism KW - Female KW - Paclitaxel -- administration & dosage KW - Hydroxamic Acids -- administration & dosage KW - Ovarian Neoplasms -- pathology KW - Apoptosis -- drug effects KW - Paclitaxel -- pharmacology KW - Antineoplastic Combined Chemotherapy Protocols -- pharmacology KW - Hydroxamic Acids -- pharmacology KW - Ovarian Neoplasms -- drug therapy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/734175123?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Science+%26+Technology&rft.atitle=Gene+Expression+Profiling+in+Daphnia+magna%2C+Part+II%3A+Validation+of+a+Copper+Specific+Gene+Expression+Signature+with+Effluent+from+Two+Copper+Mines+in+California&rft.au=Poynton%2C+Helen+C%3BZuzow%2C+Rick%3BLoguinov%2C+Alexandre+V%3BPerkins%2C+Edward+J%3BVulpe%2C+Chris+D&rft.aulast=Poynton&rft.aufirst=Helen&rft.date=2008-07-10&rft.volume=42&rft.issue=16&rft.spage=6257&rft.isbn=&rft.btitle=&rft.title=Environmental+Science+%26+Technology&rft.issn=0013936X&rft_id=info:doi/10.1021%2Fes800262k LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-12-11 N1 - Date created - 2009-12-07 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.ygyno.2009.09.039 ER - TY - JOUR T1 - In silico pharmacophore model for tabun-inhibited acetylcholinesterase reactivators: a study of their stereoelectronic properties. AN - 733804664; 20028185 AB - Organophosphorus (OP) nerve agents that inhibit acetylcholinesterase (AChE; EC 3.1.1.7) function in the nervous system, causing acute intoxication. If untreated, death can result. Inhibited AChE can be reactivated by oximes, antidotes for OP exposure. However, OP intoxication caused by the nerve agent tabun (GA) is particularly resistant to oximes, which poorly reactivate GA-inhibited AChE. In an attempt to develop a rational strategy for the discovery and design of novel reactivators with lower toxicity and increased efficacy in reactivating GA-inhibited AChE, we developed the first in silico pharmacophore model for binding affinity of GA-inhibited AChE from a set of 11 oximes. Oximes were analyzed for stereoelectronic profiles and three-dimensional quantitative structure-activity relationship pharmacophores using ab initio quantum chemical and pharmacophore generation methods. Quantum chemical methods were sequentially used from semiempirical AM1 to hierarchical ab initio calculations to determine the stereoelectronic properties of nine oximes exhibiting affinity for binding to GA-inhibited AChE in vivo. The calculated stereoelectronic properties led us to develop the in silico pharmacophore model using CATALYST methodology. Specific stereoelectronic profiles including the distance between bisquarternary nitrogen atoms of the pyridinium ring in the oximes, hydrophilicity, surface area, nucleophilicity of the oxime oxygen, and location of the molecular orbitals on the isosurfaces have important roles for potencies for reactivating GA-inhibited AChE. The in silico pharmacophore model of oxime affinity for binding to GA-inhibited AChE was found to require a hydrogen bond acceptor, a hydrogen bond donor at the two terminal regions, and an aromatic ring in the central region of the oximes. The model was found to be well-correlated (R = 0.9) with experimental oxime affinity for binding to GA-inhibited AChE. Additional stereoelectronic features relating activity with the location of molecular orbitals and weak electrostatic potential field over the aromatic rings were found to be consistent with the pharmacophore model. These results provided the first predictive pharmacophore model of oxime affinity for binding toward GA-inhibited AChE. The model may be useful for virtual screening of compound libraries to discover and/or custom synthesize more efficacious and less toxic reactivators that may be useful for GA intoxication. JF - Chemical research in toxicology AU - Bhattacharjee, Apurba K AU - Kuca, Kamil AU - Musilek, Kamil AU - Gordon, Richard K AD - Department of Regulated Laboratories, Division of Regulated Activities, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, Maryland 20910, USA. Apurba.Bhattacharjee@amedd.army.mil. Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 26 EP - 36 VL - 23 IS - 1 KW - Chemical Warfare Agents KW - 0 KW - Cholinesterase Inhibitors KW - Cholinesterase Reactivators KW - Organophosphates KW - Oximes KW - Acetylcholinesterase KW - EC 3.1.1.7 KW - tabun KW - S45M750QSH KW - Index Medicus KW - Quantum Theory KW - Stereoisomerism KW - Quantitative Structure-Activity Relationship KW - Models, Chemical KW - Drug Design KW - Binding Sites KW - Oximes -- pharmacology KW - Cholinesterase Reactivators -- chemistry KW - Cholinesterase Reactivators -- pharmacology KW - Cholinesterase Inhibitors -- toxicity KW - Organophosphates -- toxicity KW - Oximes -- chemistry KW - Chemical Warfare Agents -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733804664?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemical+research+in+toxicology&rft.atitle=In+silico+pharmacophore+model+for+tabun-inhibited+acetylcholinesterase+reactivators%3A+a+study+of+their+stereoelectronic+properties.&rft.au=Bhattacharjee%2C+Apurba+K%3BKuca%2C+Kamil%3BMusilek%2C+Kamil%3BGordon%2C+Richard+K&rft.aulast=Bhattacharjee&rft.aufirst=Apurba&rft.date=2010-01-01&rft.volume=23&rft.issue=1&rft.spage=26&rft.isbn=&rft.btitle=&rft.title=Chemical+research+in+toxicology&rft.issn=1520-5010&rft_id=info:doi/10.1021%2Ftx900192u LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-03-25 N1 - Date created - 2010-01-18 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1021/tx900192u ER - TY - JOUR T1 - Temporal characteristics of botulinum neurotoxin therapy. AN - 733795878; 20021324 AB - Botulinum neurotoxin is a pharmaceutical treatment used for an increasing number of neurological and non-neurological indications, symptoms and diseases. Despite the wealth of clinical reports that involve the timing of the therapeutic effects of this toxin, few studies have attempted to integrate these data into unified models. Secondary reactions have also been examined including the development of adverse events, resistance to repeated applications, and nerve terminal sprouting. Our primary intent for conducting this review was to gather relevant pharmacodynamic data from suitable biomedical literature regarding botulinum neurotoxins via the use of automated data-mining techniques. We envision that mathematical models will ultimately be of value to those who are healthcare decision makers and providers, as well as clinical and basic researchers. Furthermore, we hypothesize that the combination of this computer-intensive approach with mathematical modeling will predict the percentage of patients who will favorably or adversely respond to this treatment and thus will eventually assist in developing the increasingly important area of personalized medicine. JF - Expert review of neurotherapeutics AU - Lebeda, Frank J AU - Cer, Regina Z AU - Stephens, Robert M AU - Mudunuri, Uma AD - Combat Casualty Care Research Program, US Army Medical Research and Materiel Command, 504 Scott Street, Ft Detrick, MD 21702-5012, USA. frank.lebeda@amedd.army.mil Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 93 EP - 103 VL - 10 IS - 1 KW - Anti-Dyskinesia Agents KW - 0 KW - Synaptosomal-Associated Protein 25 KW - Botulinum Toxins KW - EC 3.4.24.69 KW - Index Medicus KW - Animals KW - Synaptosomal-Associated Protein 25 -- metabolism KW - Humans KW - Action Potentials -- drug effects KW - Models, Neurological KW - Computational Biology KW - Time Factors KW - Muscle, Skeletal -- drug effects KW - Models, Theoretical KW - Anti-Dyskinesia Agents -- pharmacology KW - Nervous System Diseases -- drug therapy KW - Botulinum Toxins -- therapeutic use KW - Anti-Dyskinesia Agents -- therapeutic use KW - Botulinum Toxins -- pharmacology KW - Botulinum Toxins -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733795878?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Expert+review+of+neurotherapeutics&rft.atitle=Temporal+characteristics+of+botulinum+neurotoxin+therapy.&rft.au=Lebeda%2C+Frank+J%3BCer%2C+Regina+Z%3BStephens%2C+Robert+M%3BMudunuri%2C+Uma&rft.aulast=Lebeda&rft.aufirst=Frank&rft.date=2010-01-01&rft.volume=10&rft.issue=1&rft.spage=93&rft.isbn=&rft.btitle=&rft.title=Expert+review+of+neurotherapeutics&rft.issn=1744-8360&rft_id=info:doi/10.1586%2Fern.09.134 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-03-01 N1 - Date created - 2009-12-21 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Toxicon. 2002 Jul;40(7):923-8 [12076646] J Cosmet Laser Ther. 2002 Mar;4(1):15-8 [12079632] Eur Neurol. 2002;48(1):26-9 [12138306] Dermatol Surg. 2002 Sep;28(9):817-21 [12269875] Dermatol Surg. 2003 Jan;29(1):7-13; discussion 13 [12534505] Mol Cell Neurosci. 2003 Apr;22(4):454-66 [12727443] Dermatol Surg. 2003 May;29(5):501-7; discussion 507 [12752518] Plast Reconstr Surg. 2003 Oct;112(5 Suppl):138S-140S [14504495] Annu Rev Pharmacol Toxicol. 2004;44:167-93 [14744243] Mov Disord. 2004 Mar;19 Suppl 8:S35-41 [15027052] Mov Disord. 2004 Mar;19 Suppl 8:S53-9 [15027055] Mov Disord. 2004 Mar;19 Suppl 8:S129-36 [15027065] J Pharmacol Exp Ther. 1980 Jan;212(1):16-21 [6243359] Toxicon. 1982;20(1):141-8 [7043781] Toxicon. 1992 Mar;30(3):223-5 [1529458] Mov Disord. 1993 Oct;8(4):479-83 [8232357] J R Soc Med. 1993 Aug;86(8):493-4 [8078064] Mov Disord. 1996 May;11(3):250-6 [8723140] Neurosci Lett. 1997 Mar 14;224(2):91-4 [9086464] J Physiol Paris. 1998 Apr;92(2):135-9 [9782457] Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):3200-5 [10077661] Mov Disord. 1999 Mar;14(2):307-12 [10091625] Brain. 1962 Mar;85:109-20 [14484759] J Mol Biol. 2005 Mar 4;346(4):1083-93 [15701519] Eur Neurol. 2005;53(1):3-9 [15650306] Bull Math Biol. 2005 May;67(3):547-61 [15820742] Mov Disord. 2005 May;20(5):592-7 [15645481] J Neural Transm (Vienna). 2005 Jul;112(7):905-13 [15526142] Appl Environ Microbiol. 2005 Aug;71(8):4478-86 [16085839] J Neurol. 2005 Aug;252(8):904-7 [15761672] Neurology. 2005 Nov 8;65(9):1423-9 [16275831] Emerg Infect Dis. 2005 Oct;11(10):1578-83 [16318699] Eur J Neurol. 2006 Feb;13 Suppl 1:11-5 [16417592] Science. 2006 Apr 28;312(5773):592-6 [16543415] Nucleic Acids Res. 2006 Jul 1;34(Web Server issue):W748-52 [16845112] Eur J Neurol. 2006 Dec;13 Suppl 4:1-9 [17112344] J Pharmacol Exp Ther. 2007 Jan;320(1):410-8 [17050783] Neurology. 2006 Dec 26;67(12):2233-5 [17190952] Eur J Neurosci. 2007 May;25(9):2697-704 [17561839] Expert Rev Neurother. 2007 Jun;7(6):637-47 [17563247] Acta Neurol Scand. 2008 Feb;117(2):73-84 [17850405] Parkinsonism Relat Disord. 2007;13 Suppl 3:S362-8 [18267265] J Am Acad Dermatol. 2008 Mar;58(3):517-8 [18280358] Neurology. 2008 May 6;70(19):1691-8 [18458229] Neurology. 2008 May 6;70(19):1699-706 [18458230] Neurology. 2008 May 6;70(19):1707-14 [18458231] J Cosmet Laser Ther. 2008 Jun;10(2):93-102 [18569262] J Physiol. 2008 Jul 1;586(13):3163-82 [18467364] Neurol Clin. 2008 May;26 Suppl 1:43-53 [18603167] J Pharmacokinet Pharmacodyn. 2008 Jun;35(3):251-67 [18551355] Mov Disord. 2008 Jul 30;23(10):1353-60 [18546321] Skin Therapy Lett. 2008 Jul-Aug;13(6):1-4 [18806905] BMC Med Inform Decis Mak. 2008;8:60 [19108734] Mov Disord. 2009 Jan 30;24(2):231-6 [18951439] Arch Facial Plast Surg. 2009 Mar-Apr;11(2):77-83 [19289677] J Neural Transm (Vienna). 2009 Apr;116(4):437-41 [19319477] Nucleic Acids Res. 2009 Jul;37(Web Server issue):W441-5 [19395593] Trials. 2009;10:43 [19545379] Toxicon. 2009 Oct;54(5):676-82 [19341758] Int Urol Nephrol. 2010 Jun;42(2):383-91 [19572209] Dermatol Clin. 2004 Apr;22(2):221-6 [15222583] Genome Biol. 2004;5(10):R80 [15461798] Exp Neurol. 1975 Jun;47(3):544-57 [236911] Fed Proc. 1980 Jan;39(1):42-7 [6985870] Physiol Rev. 2000 Apr;80(2):717-66 [10747206] J Pharmacol Exp Ther. 2001 Mar;296(3):980-6 [11181932] J Neurol. 2001 Apr;248 Suppl 1:11-3 [11357232] Toxicon. 2001 Sep;39(9):1309-15 [11384718] Expert Opin Pharmacother. 2001 Dec;2(12):1985-94 [11825330] Drugs. 2002;62(4):705-22 [11893235] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1586/ern.09.134 ER - TY - JOUR T1 - Iranian Ambitions: The Gulf States in the Shadow of Iran AN - 60544624; 201009606 AB - Discussion begins with a brief description of the Gulf Security Dialogue (GSD) between the US & Gulf Cooperation Council (GCC) before questioning whether the GSD provide sufficient strength & protection against the emerging Iranian threat in the region. Iran's presence in the Persian Gulf is examined before reviewing US interest in Gulf security. Attention is given to GSD implementation under the Bush administration & the state of Gulf security under the Obama administration, given the latter's intention to engage diplomatically with the Islamic Republic. It is noted that Iran has, thus far, ignored such diplomatic efforts. It is contended that the US should use the GSD to counter Iranian assertiveness, but that, while necessary, the GSD is insufficient to complete the task in light of undermining conciliatory US gestures toward Iran. Adapted from the source document. JF - Middle East Quarterly AU - Knapp, Patrick AD - Minnesota Army National Guard, Fort Huachuca, Arizona Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 49 EP - 60 PB - Middle East Forum, Philadelphia, PA VL - 17 IS - 1 SN - 1073-9467, 1073-9467 KW - Iran KW - Management KW - International Cooperation KW - Islam KW - United States of America KW - Implementation KW - Threat KW - National Security KW - article KW - 9063: international relations; international relations UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60544624?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Middle+East+Quarterly&rft.atitle=Iranian+Ambitions%3A+The+Gulf+States+in+the+Shadow+of+Iran&rft.au=Knapp%2C+Patrick&rft.aulast=Knapp&rft.aufirst=Patrick&rft.date=2010-01-01&rft.volume=17&rft.issue=1&rft.spage=49&rft.isbn=&rft.btitle=&rft.title=Middle+East+Quarterly&rft.issn=10739467&rft_id=info:doi/ LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2010-03-05 N1 - Last updated - 2016-09-28 N1 - CODEN - MEQUFZ N1 - SubjectsTermNotLitGenreText - Iran; United States of America; National Security; Management; International Cooperation; Threat; Implementation; Islam ER - TY - JOUR T1 - Soldiers as Police Officers/ Police Officers as Soldiers: Role Evolution and Revolution in the United States AN - 60502304; 201014390 AB - The military and police professions share a number of common facets, but in spite of surface similarities, the two professions are significantly different. Consequently, the evidence indicating a convergence of primary aspects of the two roles presages an important societal development, with substantial implications on several levels. Thus, this article has several objectives. First, it reviews the evidence indicating role convergence, that is, evidence that significant segments of police operations in the United States have taken on military characteristics; and evidence indicating that many U.S. military initiatives have taken on policing characteristics. Next, using the notion of internal and external role-change 'drivers', it examines how such role shifts occur and considers some political and legal implications of the shift. Third, the article compares the role orientations and job demands of both professions, identifying the important differences inherent in the two roles and presenting an analysis of the occupational implications of role convergence for job holders, job evaluators, and job 'clients' (i.e., ordinary citizens). The last section considers the implications of role convergence for role management. Adapted from the source document. JF - Armed Forces & Society AU - Campbell, Donald J AU - Campbell, Kathleen M AD - United States Military Academy Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 327 EP - 350 PB - Sage Publications, Thousand Oaks CA VL - 36 IS - 2 SN - 0095-327X, 0095-327X KW - role convergence police-military fusion military job redefinition KW - Armed Forces KW - Police KW - Roles KW - article KW - 9091: government/political systems; armed forces UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60502304?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Armed+Forces+%26+Society&rft.atitle=Soldiers+as+Police+Officers%2F+Police+Officers+as+Soldiers%3A+Role+Evolution+and+Revolution+in+the+United+States&rft.au=Campbell%2C+Donald+J%3BCampbell%2C+Kathleen+M&rft.aulast=Campbell&rft.aufirst=Donald&rft.date=2010-01-01&rft.volume=36&rft.issue=2&rft.spage=327&rft.isbn=&rft.btitle=&rft.title=Armed+Forces+%26+Society&rft.issn=0095327X&rft_id=info:doi/10.1177%2F0095327X09335945 LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2010-04-07 N1 - Last updated - 2016-09-28 N1 - CODEN - AFSOD2 N1 - SubjectsTermNotLitGenreText - Police; Armed Forces; Roles DO - http://dx.doi.org/10.1177/0095327X09335945 ER - TY - JOUR T1 - A New Angle on the U.S. Military's Emphasis on Developing Cross-Cultural Competence: Connecting In-Ranks' Cultural Diversity to Cross-Cultural Competence AN - 60493643; 201014416 AB - This article forwards a novel approach regarding the U.S. military's growing focus on building cross-cultural competence. This piece argues that a link exists between the armed forces' internal cultural diversity issues and the military's objective to heighten its ability to work effectively in foreign cultures. Cross-cultural competence means the knowledge, attitudes, and behavioral repertoire and skill sets that military members require to accomplish all given tasks and missions involving cultural diversity. Despite the military's noteworthy historic progress in the area of building a diverse and cohesive force, it possesses some ongoing cultural diversity problems. The article examines three concerns within the ranks of the U.S. military: signs of religious intolerance, some ongoing resistance toward women service members, and antihomosexual attitudes and conduct. This piece explores these concerns and also argues that ameliorating these cultural diversity issues will contribute to building cross-cultural competence in the military. Adapted from the source document. JF - Armed Forces & Society AU - Hajjar, Remi M AD - United States Army remi.hajjar@us.army.mil Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 247 EP - 263 PB - Sage Publications, Thousand Oaks CA VL - 36 IS - 2 SN - 0095-327X, 0095-327X KW - cross-cultural competence culture-general factors culture-specific factors internal cultural diversity issues KW - Prejudice KW - United States of America KW - Homophobia KW - Armed Forces KW - Cultural Sensitivity KW - Sexism KW - article KW - 9091: government/political systems; armed forces UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60493643?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Armed+Forces+%26+Society&rft.atitle=A+New+Angle+on+the+U.S.+Military%27s+Emphasis+on+Developing+Cross-Cultural+Competence%3A+Connecting+In-Ranks%27+Cultural+Diversity+to+Cross-Cultural+Competence&rft.au=Hajjar%2C+Remi+M&rft.aulast=Hajjar&rft.aufirst=Remi&rft.date=2010-01-01&rft.volume=36&rft.issue=2&rft.spage=247&rft.isbn=&rft.btitle=&rft.title=Water+Resources+Research&rft.issn=00431397&rft_id=info:doi/10.1029%2F2006WR005577 LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2010-04-07 N1 - Last updated - 2016-09-28 N1 - CODEN - AFSOD2 N1 - SubjectsTermNotLitGenreText - Armed Forces; Cultural Sensitivity; Prejudice; Sexism; Homophobia; United States of America DO - http://dx.doi.org/10.1177/0095327X09339898 ER - TY - JOUR T1 - Fortress at Sea? The Carrier Invulnerability Myth AN - 58842211; 2010-461011 AB - Examines US aircraft carrier vulnerability to attack given the advent of next-generation weapons technology & unconventional or asymmetric threats. It is contended that the presumption of carrier invulnerability is dangerous. Adapted from the source document. JF - U.S. Naval Institute Proceedings AU - Patch, John AD - U.S. Army War Coll Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 16 EP - 20 PB - U.S. Naval Institute, Annapolis, MD VL - 136 IS - 1 SN - 0041-798X, 0041-798X KW - Military and defense policy - Military equipment and weapons KW - United States KW - Aircraft carriers KW - Technology KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58842211?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=U.S.+Naval+Institute+Proceedings&rft.atitle=Fortress+at+Sea%3F+The+Carrier+Invulnerability+Myth&rft.au=Patch%2C+John&rft.aulast=Patch&rft.aufirst=John&rft.date=2010-01-01&rft.volume=136&rft.issue=1&rft.spage=16&rft.isbn=&rft.btitle=&rft.title=U.S.+Naval+Institute+Proceedings&rft.issn=0041798X&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2010-03-05 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - United States; Aircraft carriers; Technology ER - TY - JOUR T1 - Forward in Africa: USAFRICOM and the U.S. Army in Africa AN - 58839366; 2010-477226 AB - AFRICOM and U.S. Army Africa can deliver low-cost, sustained security engagement in Africa. The command is well on its way to transforming from a tactical contingency headquarters to a regionally focused theater army headquarters capable of synchronizing all U.S. Army activity in Africa, conducting sustained security engagement with African land forces, and responding promptly and effectively to a variety of crises in Africa. Adapted from the source document. JF - Military Review AU - Garrett, William B AU - Mariano, Stephen J AU - Sanderson, Adam AD - U.S. Army Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 15 EP - 25 PB - US Army Combined Arms Center, Leavenworth, KS VL - 90 IS - 1 SN - 0026-4148, 0026-4148 KW - International relations - International organizations KW - International relations - International peace and security KW - United States Africa Command KW - Africa KW - United States Army KW - Regional security KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58839366?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Military+Review&rft.atitle=Forward+in+Africa%3A+USAFRICOM+and+the+U.S.+Army+in+Africa&rft.au=Garrett%2C+William+B%3BMariano%2C+Stephen+J%3BSanderson%2C+Adam&rft.aulast=Garrett&rft.aufirst=William&rft.date=2010-01-01&rft.volume=90&rft.issue=1&rft.spage=15&rft.isbn=&rft.btitle=&rft.title=Military+Review&rft.issn=00264148&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2010-04-07 N1 - SuppNotes - http://usacac.army.mil/CAC2/MilitaryReview/Archives/English/MilitaryReview_ 20 100228_art006.pdf N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - United States Africa Command; United States Army; Africa; Regional security ER - TY - JOUR T1 - Providing Security Force Assistance in an Economy of Force Battle AN - 58826623; 2010-477229 AB - The U.S. Army 1st Battalion, 35th Armor (Task Force Conqueror), fought an economy of force mission for most of the Battle of Ramadi during the summer and fall of 2006. This narrative highlights lessons learned from the deployment. Through a combination of partnering with Iraqi Security Forces, tribal engagement, aggressive Iraqi Police recruiting, and targeted U.S.-led operations, the task force was able to reestablish the Iraqi Police in Ramadi; increase the capability of our partnered Iraqi Army battalion; link the sheiks of Anbar with the government of Iraq fostering the Anbar Awakening. Figures. Adapted from the source document. JF - Military Review AU - Deane, Anthony E AD - U.S. Army Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 80 EP - 90 PB - US Army Combined Arms Center, Leavenworth, KS VL - 90 IS - 1 SN - 0026-4148, 0026-4148 KW - Military and defense policy - Military planning, strategy, and operations KW - Administration of justice - Police and law enforcement KW - Military operations KW - United States Army KW - Police KW - Iraq KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58826623?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Military+Review&rft.atitle=Providing+Security+Force+Assistance+in+an+Economy+of+Force+Battle&rft.au=Deane%2C+Anthony+E&rft.aulast=Deane&rft.aufirst=Anthony&rft.date=2010-01-01&rft.volume=90&rft.issue=1&rft.spage=80&rft.isbn=&rft.btitle=&rft.title=Military+Review&rft.issn=00264148&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2010-04-07 N1 - SuppNotes - http://usacac.army.mil/CAC2/MilitaryReview/Archives/English/MilitaryReview_ 20 100228_art014.pdf N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - United States Army; Iraq; Military operations; Police ER - TY - JOUR T1 - Implementing a Unit-Level Intervention to Reduce the Probability of Ventilator-Associated Pneumonia AN - 57353244; 201006131 AB - Background: Ventilator-associated pneumonia (VAP) is the second most common hospital-acquired infection and is associated with high morbidity and mortality rates for mechanically ventilated patients in the intensive care unit. Routine nursing interventions have been shown to reduce VAP rates. Objectives: The purpose of this study was to evaluate the effectiveness of a unit-specific education intervention that emphasized hand hygiene, head-of-the-bed elevation, and oral care. The goals were to improve staff compliance with hand washing, head-of-the-bed elevation, and oral care; to decrease VAP rates, and to decrease number of ventilator days. Methods: Two-hour observations were conducted on a convenience sample of 100 ventilated patients not diagnosed with VAP and the clinical staff that interacted with them. Instrumentation included a compliance checklist, a demographic patient survey, and the Acute Physiology and Chronic Health Evaluation PEN-registered trademark tool. Unit-specific educational interventions were designed and implemented on each participating unit. Results: The VAP and the ventilator day rates did not improve significantly. There were no significant changes in clinician adherence to hand hygiene, provision of oral care, or patient positioning. Discussion: Despite implementation of both structured and creative education, team-based approach, and frequent staff reminders, patient outcomes and staff compliance did not improve significantly. Unit-based education interventions may not be the best strategy to facilitate change. Organizations with frequent changes in personnel and leadership may not have the unit-level infrastructure necessary to attain and sustain change. Adapted from the source document. JF - Nursing Research AU - Bingham, Mona AU - Ashley, Jeffrey AU - De Jong, Marla AU - Swift, Caren AD - U.S. Army, Chief, Nursing Research Services, Brooke Army Medical Center, Ft. Sam Houston, TX 78234-6200 Mona.bingham@us.army.mil Y1 - 2010/01// PY - 2010 DA - January 2010 SP - S40 EP - S47 PB - Lippincott Williams & Wilkins, Hagerstown MD VL - 59 SN - 0029-6562, 0029-6562 KW - compliance, evidence-based practice, infection control, ventilator-associated or ventilator-acquired pneumonia KW - Oral hygiene KW - Physiology KW - Elevation KW - Compliance KW - Pneumonia KW - Ventilators KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/57353244?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Nursing+Research&rft.atitle=Implementing+a+Unit-Level+Intervention+to+Reduce+the+Probability+of+Ventilator-Associated+Pneumonia&rft.au=Bingham%2C+Mona%3BAshley%2C+Jeffrey%3BDe+Jong%2C+Marla%3BSwift%2C+Caren&rft.aulast=Bingham&rft.aufirst=Mona&rft.date=2010-01-01&rft.volume=59&rft.issue=&rft.spage=S40&rft.isbn=&rft.btitle=&rft.title=Nursing+Research&rft.issn=00296562&rft_id=info:doi/ LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-04-07 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Oral hygiene; Compliance; Ventilators; Pneumonia; Elevation; Physiology ER - TY - JOUR T1 - A Nurse-Facilitated Depression Screening Program in an Army Primary Care Clinic: An Evidence-Based Project AN - 57352593; 201008741 AB - Background: Depression, sometimes with suicidal manifestations, is a medical condition commonly seen in primary care clinics. Routine screening for depression and suicidal ideation is recommended of all adult patients in the primary care setting because it offers depressed patients a greater chance of recovery and response to treatment, yet such screening often is overlooked or omitted. Objective: The purpose of this study was to develop, to implement, and to test the efficacy of a systematic depression screening process to increase the identification of depression in family members of active duty soldiers older than 18 years at a military family practice clinic located on an Army infantry post in the Pacific. Methods: The Iowa Model of Evidence-Based Practice to Promote Quality Care was used to develop a practice guideline incorporating a decision algorithm for nurses to screen for depression. A pilot project to institute this change in practice was conducted, and outcomes were measured. Results: Before implementation, approximately 100 patients were diagnosed with depression in each of the 3 months preceding the practice change. Approximately 130 patients a month were assigned a 311.0 Code 3 months after the practice change, and 140 patients per month received screenings and were assigned the correct International Classification of Diseases, Ninth Revision Code 311.0 at 1 year. The improved screening and coding for depression and suicidality added approximately 3 minutes to the patient screening process. The education of staff in the process of screening for depression and correct coding coupled with monitoring and staff feedback improved compliance with the identification and the documentation of patients with depression. Nurses were more likely than primary care providers to agree strongly that screening for depression enhances quality of care. Discussion: Data gathered during this project support the integration of military and civilian nurse-facilitated screening for depression in the military primary care setting. The decision algorithm should be adapted and tested in other primary care environments. Adapted from the source document. JF - Nursing Research AU - Yackel, Edward E AU - McKennan, Madelyn S AU - Fox-Deise, Adrianna AD - U.S. Army Nurse Corps, McDonald Army Health Center, Fort Eustis, VA 23604 Ed.yackel@us.army.mil Y1 - 2010/01// PY - 2010 DA - January 2010 SP - S58 EP - S65 PB - Lippincott Williams & Wilkins, Hagerstown MD VL - 59 SN - 0029-6562, 0029-6562 KW - decision algorithm, depression screening, evidence-based practice, military primary care clinic KW - Screening KW - Depression KW - Nurses KW - Algorithms KW - Primary health care KW - Clinics KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/57352593?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+Slavic+Military+Studies&rft.atitle=Threats+to+and+from+Russia%3A+An+Assessment&rft.au=Blank%2C+Stephen&rft.aulast=Blank&rft.aufirst=Stephen&rft.date=2008-07-01&rft.volume=21&rft.issue=3&rft.spage=491&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+Slavic+Military+Studies&rft.issn=13518046&rft_id=info:doi/10.1080%2F13518040802313746 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-04-07 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Depression; Screening; Primary health care; Clinics; Algorithms; Nurses ER - TY - JOUR T1 - Oral-Maxillofacial Injury Surveillance in the Department of Defense, 1996-2005 AN - 57352236; 201007694 AB - Introduction: Oral-maxillofacial injuries can lead to deformity & malfunction, greatly diminishing quality of life & worker productivity. Data suggest that over 10% of civilian emergency room visits are due to craniofacial injuries. The size & scope of oral-maxillofacial injuries in the military is not well understood. This study reports U.S. military rates of oral-maxillofacial injuries, causes of oral-maxillofacial hospitalizations, & recommends approaches to improving surveillance, research, & prevention. Methods: Active duty U.S. military personnel who sought inpatient or outpatient treatment for one or more oral-maxillofacial injuries from 1996 to 2005 were identified in the Defense Medical Surveillance System using ICD-9-CM diagnosis codes associated with oral-maxillofacial injuries. ICD-9-CM diagnosis codes were divided into two categories: oral-maxillofacial wounds & oral-maxillofacial fractures. Results: The oral-maxillofacial fracture rates for men were consistently 1.5 to 2 times higher than those for women, with 2000-2005 rates between 1.2 & 1.5/1000 person-years for men & between 0.7 & 1.0/1000 person-years for women. Wound rates for men were similar to those for women for all years examined (p<0.001), with 2000-2005 rates ranging from 11.0 to 14.6/1000 person-years for men & 12.2-14.8/1000 person-years for women. Compared to the over-40 age group, active duty personnel under age 25 had the highest rates of both oral-maxillofacial fractures & wounds (p<0.001). Among those injuries with a cause recorded, fighting (13.5%) was the leading cause of oral-maxillofacial injury hospitalizations in 2005. Conclusions: Oral-maxillofacial injuries can & should be monitored using military medical surveillance data. Surveillance efforts would be enhanced by the addition of dental care data. There is also a need for additional quality intervention studies on the strategies to prevent oral & craniofacial injury. Adapted from the source document. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Mitchener, Timothy A AU - Canham-Chervak, Michelle AD - Directorate Epidemiology Disease Surveillance, U.S. Army Center Health Promotion Preventive Medicine, Aberdeen, MD Y1 - 2010/01// PY - 2010 DA - January 2010 SP - S86 EP - S93 PB - Elsevier Science, New York NY VL - 38 IS - S1 SN - 0749-3797, 0749-3797 KW - Diagnosis KW - Hospitalization KW - Injuries KW - Fractures KW - Lesions KW - Surveillance KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/57352236?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Oral-Maxillofacial+Injury+Surveillance+in+the+Department+of+Defense%2C+1996-2005&rft.au=Mitchener%2C+Timothy+A%3BCanham-Chervak%2C+Michelle&rft.aulast=Mitchener&rft.aufirst=Timothy&rft.date=2010-01-01&rft.volume=38&rft.issue=S1&rft.spage=S86&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2009.10.016 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-04-07 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Injuries; Surveillance; Lesions; Hospitalization; Fractures; Diagnosis DO - http://dx.doi.org/10.1016/j.amepre.2009.10.016 ER - TY - JOUR T1 - A Process to Identify Military Injury Prevention Priorities Based on Injury Type and Limited Duty Days AN - 57348971; 201008125 AB - Background: The Logistics Management Institute initially developed a medical cost-avoidance model (MCAM) to estimate the costs associated with the failure to eliminate or control health hazards of army materiel systems during 1997. Methods: Presented is an updated version of the MCAM that uses cost factors for individual health hazard categories. The earlier MCAM calculated army materiel acquisition-life cycle medical costs based on a single cost factor for all hazard categories. Results: The Army's Health Hazard Assessment (HHA) Program, which uses the MCAM while assessing 18 types of health hazards commonly found in materiel undergoing the acquisition process, recognized the need to refine the MCAM to be hazard-type specific. These hazard types have unique cost factors & serve as the basis for the revised model. Conclusions: The revision will assist the HHA program in targeting health hazards that have the potential to affect soldier health & readiness. Adapted from the source document. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Ruscio, Bruce A AU - Jones, Bruce H AU - Bullock, Steven H AU - Burnham, Bruce R AU - Canham-Chervak, Michelle AU - Rennix, Christopher P AU - Wells, Timothy S AU - Smith, Jack W AD - United States Army Center Health Promotion Preventive Medicine, Aberdeen, MD Y1 - 2010/01// PY - 2010 DA - January 2010 SP - S34 EP - S41 PB - Elsevier Science, New York NY VL - 38 IS - S1 SN - 0749-3797, 0749-3797 KW - Hazards KW - Armies KW - Health costs KW - Injuries KW - Revisions KW - Health hazards KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/57348971?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=A+Process+to+Identify+Military+Injury+Prevention+Priorities+Based+on+Injury+Type+and+Limited+Duty+Days&rft.au=Ruscio%2C+Bruce+A%3BJones%2C+Bruce+H%3BBullock%2C+Steven+H%3BBurnham%2C+Bruce+R%3BCanham-Chervak%2C+Michelle%3BRennix%2C+Christopher+P%3BWells%2C+Timothy+S%3BSmith%2C+Jack+W&rft.aulast=Ruscio&rft.aufirst=Bruce&rft.date=2010-01-01&rft.volume=38&rft.issue=S1&rft.spage=S34&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2009.10.002 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-04-07 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Health costs; Health hazards; Armies; Injuries; Hazards; Revisions DO - http://dx.doi.org/10.1016/j.amepre.2009.10.002 ER - TY - JOUR T1 - Care of the Patient With Enteral Tube Feeding: An Evidence-Based Practice Protocol AN - 57346502; 201007252 AB - Background: Care of patients with enteral feeding tubes often is based on tradition and textbook guidance rather than best evidence. Care practices can vary widely both between and within institutions, and this was the case at a northeastern military medical center that served as the site for this evidence-based protocol development and implementation project Objectives: The purpose of this study was to describe the development and implementation of an evidence-based clinical protocol for care of patients with enteral feeding tubes. Methods: This was an evidence-based implementation project with pretest-posttest measures. Protocol data collection occurred both before and after implementation of the protocol. Data collection tools were based on the literature review and included three domains: (a) documentation of patient procedures, (b) nursing knowledge of each of the specific procedures, and (c) environment of care. Descriptive statistics and data were analyzed using independent samples t tests. Results: Overall staff knowledge of enteral feedings and methods used to unclog both large- and small-bore feeding tubes differed significantly before and after implementation (p < .05). Staff knowledge regarding the danger of using blue dye in feeding solution was significant (p < .001). There was improvement also in administration of medications separately rather than mixed together and in head of bed elevation of patients with feeding tubes. There was a 10% improvement in documentation of patient family education and a 15% improvement in recording fluid flushes during medication administration. After implementation, environment of care data collection showed 100% of patients with head of bed elevated and with functioning suction available, an improvement over levels before implementation. Discussion: Care must be taken in the interpretation of these findings because it was generally not the same nurses who answered both surveys. High staff turnover within this military hospital also affected sustainment of the protocol implementation. Maintenance activities must be constant and visible within the organization. A champion for evidence-based practice greatly enhances uptake and maintenance of nursing practice change. Adapted from the source document. JF - Nursing Research AU - Kenny, Deborah J AU - Goodman, Petra AD - 350 S. Clinton St. Apt 1D, Denver, CO 80247 deb.kenny@us.army.mil Y1 - 2010/01// PY - 2010 DA - January 2010 SP - S22 EP - S31 PB - Lippincott Williams & Wilkins, Hagerstown MD VL - 59 SN - 0029-6562, 0029-6562 KW - enteral feeding, practice protocol, quality assessment KW - Evidence based KW - Feeding KW - Medical records KW - Nursing KW - Patient care KW - Artificial feeding KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/57346502?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Nursing+Research&rft.atitle=Care+of+the+Patient+With+Enteral+Tube+Feeding%3A+An+Evidence-Based+Practice+Protocol&rft.au=Kenny%2C+Deborah+J%3BGoodman%2C+Petra&rft.aulast=Kenny&rft.aufirst=Deborah&rft.date=2010-01-01&rft.volume=59&rft.issue=&rft.spage=S22&rft.isbn=&rft.btitle=&rft.title=Nursing+Research&rft.issn=00296562&rft_id=info:doi/ LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-04-07 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Artificial feeding; Evidence based; Patient care; Nursing; Feeding; Medical records ER - TY - JOUR T1 - Epidemiology of Hearing Impairment and Noise-Induced Hearing Injury among U.S. Military Personnel, 2003-2005 AN - 57345791; 201006994 AB - Introduction: Rates of noise-induced hearing injury (NIHI) among U.S. active duty military have not been previously described using available military medical surveillance data. Methods: NIHI were identified in the Defense Medical Surveillance System (DMSS) using a list of ICD-9-CM diagnosis codes selected in collaboration with military audiologists. To provide a more comprehensive view of the NIHI problem, NIHI-related ICD-9 codes beyond the traditional 388 noise injury-code set were included. Visit rates by gender & age group are reported by quarter, 2003-2005. Overall frequencies & rates by occupational specialty, 2003-2005, are also described. Results: From 2003 to 2005, rates for men were significantly higher than rates for women, with rate ratios (RR) ranging from 1.15 (95% CI =1.07, 1.23) to 1.78 (95% CI= 1.62, 1.93). Rates among women ranged from 2.9 to 6.2 per 1000 person-years; rates among men ranged from 4.5 to 6.7 per 1000 person-years. NIHI rates were highest among those aged > or = to 40 years & lowest among those aged 17-19 years, with RRs ranging from 3.06 (95% CI=2.77, 3.40) to 5.51 (95% CI=4.88, 6.30) during this time period. Among occupational groups, general officers/executives had the highest NIHI rate over this time period (29.5/1000 person-years), followed by enlisted personnel in training (14.3/1000 person-years) & scientists & professionals (12.8/1000 person-years). Conclusions: While data on outpatient injury causes & use of hearing protection are also needed to guide the future design &/or modification of interventions, existing military medical surveillance provides essential information for tracking NIHI & monitoring NIHI intervention effects. Adapted from the source document. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Helfer, Thomas M AU - Canham-Chervak, Michelle AU - Canada, Sara AU - Mitchener, Timothy A AD - Army Hearing Program, U.S. Army Center Health Promotion Preventive Medicine, Aberdeen, MD Y1 - 2010/01// PY - 2010 DA - January 2010 SP - S71 EP - S77 PB - Elsevier Science, New York NY VL - 38 IS - S1 SN - 0749-3797, 0749-3797 KW - Injuries KW - Interventions KW - Hearing KW - Hearing impairment KW - Tracking KW - Surveillance KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/57345791?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Epidemiology+of+Hearing+Impairment+and+Noise-Induced+Hearing+Injury+among+U.S.+Military+Personnel%2C+2003-2005&rft.au=Helfer%2C+Thomas+M%3BCanham-Chervak%2C+Michelle%3BCanada%2C+Sara%3BMitchener%2C+Timothy+A&rft.aulast=Helfer&rft.aufirst=Thomas&rft.date=2010-01-01&rft.volume=38&rft.issue=S1&rft.spage=S71&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2009.10.025 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-04-07 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Injuries; Hearing; Surveillance; Hearing impairment; Interventions; Tracking DO - http://dx.doi.org/10.1016/j.amepre.2009.10.025 ER - TY - JOUR T1 - Public Health and Risk Management: A Hybridized Approach to Military Injury Prevention AN - 57345255; 201006904 AB - Injuries represent the leading problem of U.S. military personnel across the spectrum of health, from deaths & disabilities to hospitalization & those requiring only outpatient treatment. More serious injuries result from accidents than any other cause, including combat. A s consequence of knowledge about the magnitude of the injury problem for the U.S. military & the belief that "world-class organizations do not tolerate preventable accidents," in May of 2003 the U.S. Secretary of Defense challenged the Department of Defense with aggressive accident-reduction goals. The secretary also created the Defense Safety Oversight Council (DSOC) to provide governance over the department's accident-reduction initiatives. To support execution of this responsibility, the DSOC chartered nine task forces, each covering a specific mission or mission support functional area. The Military Training Task Force (MTTF) was created to study & recommend policies, programs, & investments to achieve accident reductions in military ground training. Adapted from the source document. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Gunlicks, James B AU - Patton, James T AU - Miller, Scott F AU - Atkins, Mark G AD - Office Director Army Safety, Washington, DC e-mail c/o: james.patton@hqda.army.mil Y1 - 2010/01// PY - 2010 DA - January 2010 SP - S214 EP - S216 PB - Elsevier Science, New York NY VL - 38 IS - S1 SN - 0749-3797, 0749-3797 KW - Secretaries KW - Accidents KW - Magnitude KW - Injuries KW - Task forces KW - Governance KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/57345255?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Public+Health+and+Risk+Management%3A+A+Hybridized+Approach+to+Military+Injury+Prevention&rft.au=Gunlicks%2C+James+B%3BPatton%2C+James+T%3BMiller%2C+Scott+F%3BAtkins%2C+Mark+G&rft.aulast=Gunlicks&rft.aufirst=James&rft.date=2010-01-01&rft.volume=38&rft.issue=S1&rft.spage=S214&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2009.10.017 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-04-07 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Injuries; Accidents; Task forces; Secretaries; Magnitude; Governance DO - http://dx.doi.org/10.1016/j.amepre.2009.10.017 ER - TY - JOUR T1 - Systematic Review of the Parachute Ankle Brace: Injury Risk Reduction and Cost Effectiveness AN - 57336925; 201007304 AB - Introduction: Military parachuting has been shown to result in injuries. This investigation systematically reviewed studies examining the influence of the parachute ankle brace (PAB) on injuries during military parachuting & performed a cost-effectiveness analysis. Evidence acquisition: Parachute ankle brace studies were obtained from seven databases, personal contacts, & other sources. Investigations were reviewed if they contained original, quantitative information on PAB use & injuries during parachuting. Meta-analysis was performed using a general variance-based meta-analysis method that calculated summary risk ratios (SRR) & 95% CIs. Evidence synthesis: Five studies met the review criteria. Compared with PAB users, PAB non-users had a higher risk of ankle injuries (SRR=2.1, 95% CI=1.8-2.5); ankle sprains (SRR=2.1, 95% CI=1.4-3.1); ankle fractures (SRR=1.8, 95% CI=1.1-2.9); & all parachuting injuries combined (SRR=1.2, 95% CI=1.1-1.4). The PAB had little effect on lower body injuries exclusive of the ankle (SRR [no PAB/PAB]=0.9, 95% CI=0.7-1.2). Cost-effectiveness analysis estimated that, for every dollar expended on the PAB, a savings of about $7 to $9 could be achieved in medical & personnel costs. Conclusions: The PAB reduces ankle injuries by about half & is a cost effective device that should be worn during military airborne operations to reduce injury risk. Adapted from the source document. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Knapik, Joseph J AU - Spiess, Anita AU - Swedler, David I AU - Grier, Tyson L AU - Darakjy, Salima S AU - Jones, Bruce H AD - Epidemiology Disease Surveillance, U.S. Army Center Health Promotion Preventive Medicine, Aberdeen, MD Y1 - 2010/01// PY - 2010 DA - January 2010 SP - S182 EP - S188 PB - Elsevier Science, New York NY VL - 38 IS - S1 SN - 0749-3797, 0749-3797 KW - Savings KW - Injuries KW - Personnel KW - Ankles KW - Cost effectiveness KW - Risk reduction KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/57336925?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Systematic+Review+of+the+Parachute+Ankle+Brace%3A+Injury+Risk+Reduction+and+Cost+Effectiveness&rft.au=Knapik%2C+Joseph+J%3BSpiess%2C+Anita%3BSwedler%2C+David+I%3BGrier%2C+Tyson+L%3BDarakjy%2C+Salima+S%3BJones%2C+Bruce+H&rft.aulast=Knapik&rft.aufirst=Joseph&rft.date=2010-01-01&rft.volume=38&rft.issue=S1&rft.spage=S182&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2009.10.012 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-04-07 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Injuries; Ankles; Cost effectiveness; Risk reduction; Savings; Personnel DO - http://dx.doi.org/10.1016/j.amepre.2009.10.012 ER - TY - JOUR T1 - The U.S. Army Medical Department Commitment to Injury Reduction AN - 57336097; 201008196 AB - Medical surveillance data demonstrate that injuries are the leading health problem of the U.S. Army, resulting in over 900,000 injury-related encounters with Army medical providers in 2006. The Army consistently experiences the highest injury rates compared to other services, which places a constant strain on the Army's medical & personnel systems & has a negative impact on unit deployment readiness. Unlike other health conditions that can be effectively reduced by vaccination, counseling, or other preventive medical efforts, injuries cannot be prevented through medical efforts alone. Rather, partnerships with safety & operational commanders are essential to achieve desired reductions, as they have direct & routine contact with our soldiers & control the environments & circumstances in which injuries occur. Ultimately, it is the commander who has responsibility for preventing injuries to soldiers & has a major concern for their well-being. Adapted from the source document. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Schoomaker, Eric B AD - Office Surgeon General Army, Falls Church, VA eric.schoomaker@us.army.mil Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 1 PB - Elsevier Science, New York NY VL - 38 IS - S1 SN - 0749-3797, 0749-3797 KW - Armies KW - Injuries KW - Commanders KW - Soldiers KW - Partnerships KW - Surveillance KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/57336097?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Marine+Environmental+Research&rft.atitle=Perturbation+of+gene+expression+and+steroidogenesis+with+in+vitro+exposure+of+fathead+minnow+ovaries+to+ketoconazole&rft.au=Perkins%2C+E+J%3BGarcia-Reyero%2C+N%3BVilleneuve%2C+D+L%3BMartinovic%2C+D%3BBrasfield%2C+S+M%3BBlake%2C+L+S%3BBrodin%2C+J+D%3BDenslow%2C+N+D%3BAnkley%2C+G+T&rft.aulast=Perkins&rft.aufirst=E&rft.date=2008-07-01&rft.volume=66&rft.issue=1&rft.spage=113&rft.isbn=&rft.btitle=&rft.title=Marine+Environmental+Research&rft.issn=01411136&rft_id=info:doi/10.1016%2Fj.marenvres.2008.02.072 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-04-07 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Armies; Injuries; Commanders; Soldiers; Surveillance; Partnerships DO - http://dx.doi.org/10.1016/j.amepre.2009.10.020 ER - TY - JOUR T1 - Eye Injury Surveillance in the U.S. Department of Defense, 1996-2005 AN - 57333607; 201007024 AB - Background: Consistent with the public health approach to prevention, surveillance analyses are needed to fully understand a health problem. U.S. military eye injury rates have not been fully described using medical surveillance data. Methods: Medical visit data on active duty personnel, 1996-2005, & causes of eye injury hospitalizations (identified by Standard NATO Agreement injury cause codes) were obtained from the Defense Medical Surveillance System. Eye injury-related ICD-9-CM codes beyond the traditional 800-999 injury code set were included. Rates by age & gender are reported for 1996-2005, along with the frequency of causes of injury hospitalizations & leading eye injury diagnoses for 2005. Results: Eye injury rates among active duty military personnel increased from 1996 to 2005 among both men & women (p or = to 40 years compared to those aged 17-19 years (rate ratios=1.17 [95% CI=1.11, 1.24] to 1.24 [95% CI=1.18, 1.31]). Leading causes of eye injury hospitalizations were ordnance handling (16.9%), enemy action (13.1%), & fighting (11.9%). Conclusions: Medical surveillance data enable the assessment & monitoring of overall active duty eye injury rates, trends, & causes. Outpatient data could be improved with the addition of cause of injury codes & eye protection use. Current data suggest that continued use of eye protection during ordnance handling, combat, motor vehicle use, & sports could help reduce eye injury rates. Adapted from the source document. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Hilber, David AU - Mitchener, Timothy A AU - Stout, James AU - Hatch, Brian AU - Canham-Chervak, Michelle AD - U.S. Army Center for Health Promotion & Preventive Medicine, Aberdeen, MD Y1 - 2010/01// PY - 2010 DA - January 2010 SP - S78 EP - S85 PB - Elsevier Science, New York NY VL - 38 IS - S1 SN - 0749-3797, 0749-3797 KW - Hospitalization KW - Injuries KW - Eye injuries KW - Sports KW - Surveillance KW - Public health KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/57333607?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Eye+Injury+Surveillance+in+the+U.S.+Department+of+Defense%2C+1996-2005&rft.au=Hilber%2C+David%3BMitchener%2C+Timothy+A%3BStout%2C+James%3BHatch%2C+Brian%3BCanham-Chervak%2C+Michelle&rft.aulast=Hilber&rft.aufirst=David&rft.date=2010-01-01&rft.volume=38&rft.issue=S1&rft.spage=S78&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2009.10.015 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-04-07 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Eye injuries; Surveillance; Injuries; Hospitalization; Public health; Sports DO - http://dx.doi.org/10.1016/j.amepre.2009.10.015 ER - TY - JOUR T1 - Effect on Injuries of Assigning Shoes Based on Foot Shape in Air Force Basic Training AN - 57332814; 201007303 AB - Background: This study examined whether assigning running shoes based on the shape of the bottom of the foot (plantar surface) influenced injury risk in Air Force Basic Military Training (BMT) & examined risk factors for injury in BMT. Methods: Data were collected from BMT recruits during 2007; analysis took place during 2008. After foot examinations, recruits were randomly consigned to either an experimental group (E, n=1042 men, 375 women) or a control group (C, n=913 men, 346 women). Experimental group recruits were assigned motion control, stability, or cushioned shoes for plantar shapes indicative of low, medium, or high arches, respectively. Control group recruits received a stability shoe regardless of plantar shape. Injuries during BMT were determined from outpatient visits provided from the Defense Medical Surveillance System. Other injury risk factors (fitness, smoking, physical activity, prior injury, menstrual history, & demographics) were obtained from a questionnaire, existing databases, or BMT units. Results: Multivariate Cox regression controlling for other risk factors showed little difference in injury risk between the groups among men (hazard ratio [E/C]=1.11, 95% CI=0.89-1.38) or women (hazard ratio [E/C]=1.20, 95% CI= 0.90-1.60). Independent injury risk factors among both men & women included low aerobic fitness & cigarette smoking. Conclusions: This prospective study demonstrated that assigning running shoes based on the shape of the plantar surface had little influence on injury risk in BMT even after controlling for other injury risk factors. Adapted from the source document. [Copyright American Journal of Preventive Medicine; published by Elsevier Inc.] JF - American Journal of Preventive Medicine AU - Knapik, Joseph J AU - Brosch, Lorie C AU - Venuto, Margaret AU - Swedler, David I AU - Bullock, Steven H AU - Gaines, Lorraine S AU - Murphy, Ryan J AU - Tchandja, Juste AU - Jones, Bruce H AD - Epidemiology Disease Surveillance, U.S. Army Center Health Promotion Preventive Medicine, Aberdeen, MD Y1 - 2010/01// PY - 2010 DA - January 2010 SP - S197 EP - S211 PB - Elsevier Science, New York NY VL - 38 IS - S1 SN - 0749-3797, 0749-3797 KW - Hazards KW - Smoking KW - Airforces KW - Recruits KW - Risk factors KW - Aerobic fitness KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/57332814?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Preventive+Medicine&rft.atitle=Effect+on+Injuries+of+Assigning+Shoes+Based+on+Foot+Shape+in+Air+Force+Basic+Training&rft.au=Knapik%2C+Joseph+J%3BBrosch%2C+Lorie+C%3BVenuto%2C+Margaret%3BSwedler%2C+David+I%3BBullock%2C+Steven+H%3BGaines%2C+Lorraine+S%3BMurphy%2C+Ryan+J%3BTchandja%2C+Juste%3BJones%2C+Bruce+H&rft.aulast=Knapik&rft.aufirst=Joseph&rft.date=2010-01-01&rft.volume=38&rft.issue=S1&rft.spage=S197&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Preventive+Medicine&rft.issn=07493797&rft_id=info:doi/10.1016%2Fj.amepre.2009.10.013 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-04-07 N1 - Last updated - 2016-09-27 N1 - CODEN - AJPMEA N1 - SubjectsTermNotLitGenreText - Risk factors; Recruits; Airforces; Smoking; Hazards; Aerobic fitness DO - http://dx.doi.org/10.1016/j.amepre.2009.10.013 ER - TY - JOUR T1 - Collaborating Across Services to Advance Evidence-Based Nursing Practice AN - 57329344; 201007253 AB - Background: Military medical treatment facilities offer a unique environment in which to develop a culture of evidence-based practice (EBP). Distinctive issues arise in the context of changed patient care demographics because of a war-injured population. These issues offer an opportunity to enhance the quality of care through the use and adaptation of research findings in this special nursing environment. In addition, the colocation of two military medical centers offers the prospect of collaborative efforts to create a regional culture for nursing EBP. Objectives: The purposes of this study were to describe the processes of a collaborative project to train nurses in EBP and to share resources in developing and implementing evidence-based clinical nursing guidelines in two large military medical centers in the Northeastern United States and to discuss the collective efforts of nurse researchers, leadership, advanced practice nurses, and staff nurses in each hospital to facilitate the EBP process. Methods: A description of the organizational structure and the climate for EBP of each facility is provided followed by discussion of training efforts and the inculcation of an organizational culture for EBP. Results: Contextual barriers and facilitators were encountered throughout the project. The two nurse researchers leading the projects were able to overcome the barriers and capitalize on opportunities to promote EBP. Three evidence-based clinical practice guidelines were developed at each facility and are currently in various stages of implementation. Discussion: Despite the barriers, EBP continues to be at the forefront of military nursing practice in the U.S. National Capital Region. Clear communication and regular meetings were essential to the success of the collaborative project within and between the two military hospitals. Military-specific barriers to EBP included high team attrition and turnover because of the war mission and the usual high staff turnover at military hospitals. Military facilitators included a common mission of providing high-quality care for war-injured service members. Lessons learned from this project can be generalized to civilian facilities. Adapted from the source document. JF - Nursing Research AU - Kenny, Deborah J AU - Richard, Maggie L AU - Ceniceros, Xochitl AU - Blaize, Kelli AD - 350 S. Clinton St. Apt 1D, Denver, CO 80247 deb.kenny@us.army.mil Y1 - 2010/01// PY - 2010 DA - January 2010 SP - S11 EP - S21 PB - Lippincott Williams & Wilkins, Hagerstown MD VL - 59 SN - 0029-6562, 0029-6562 KW - evidence-based practice, practice guideline, quality assessment KW - Clinical guidelines KW - Nursing KW - Professional practices KW - Turnover KW - Facilitators KW - Military hospitals KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/57329344?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Nursing+Research&rft.atitle=Collaborating+Across+Services+to+Advance+Evidence-Based+Nursing+Practice&rft.au=Kenny%2C+Deborah+J%3BRichard%2C+Maggie+L%3BCeniceros%2C+Xochitl%3BBlaize%2C+Kelli&rft.aulast=Kenny&rft.aufirst=Deborah&rft.date=2010-01-01&rft.volume=59&rft.issue=&rft.spage=S11&rft.isbn=&rft.btitle=&rft.title=Nursing+Research&rft.issn=00296562&rft_id=info:doi/ LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-04-07 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Nursing; Facilitators; Military hospitals; Clinical guidelines; Turnover; Professional practices ER - TY - JOUR T1 - A modified acid digestion procedure for extraction of tungsten from soil AN - 50083773; 2010-019244 JF - Talanta (Oxford) AU - Bednar, Anthony J AU - Jones, W T AU - Chappell, M A AU - Johnson, D R AU - Ringelberg, David B Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 1257 EP - 1263 PB - Elsevier, Oxford VL - 80 IS - 3 SN - 0039-9140, 0039-9140 KW - water KW - soils KW - methods KW - concentration KW - experimental studies KW - acids KW - tungsten ores KW - biochemistry KW - calibration KW - solubility KW - solution KW - recovery KW - laboratory studies KW - sample preparation KW - tungsten KW - metals KW - metal ores KW - trace metals KW - geochemistry KW - 27A:Economic geology, geology of ore deposits KW - 02A:General geochemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50083773?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Talanta+%28Oxford%29&rft.atitle=A+modified+acid+digestion+procedure+for+extraction+of+tungsten+from+soil&rft.au=Bednar%2C+Anthony+J%3BJones%2C+W+T%3BChappell%2C+M+A%3BJohnson%2C+D+R%3BRingelberg%2C+David+B&rft.aulast=Bednar&rft.aufirst=Shad&rft.date=2008-07-01&rft.volume=66&rft.issue=7&rft.spage=1513&rft.isbn=&rft.btitle=&rft.title=Journal+of+oral+and+maxillofacial+surgery+%3A+official+journal+of+the+American+Association+of+Oral+and+Maxillofacial+Surgeons&rft.issn=02782391&rft_id=info:doi/ L2 - http://www.sciencedirect.com/science/journal/00399140 LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2010-01-01 N1 - Number of references - 22 N1 - Document feature - illus. incl. 4 tables N1 - Last updated - 2012-06-07 N1 - CODEN - TLNTA2 N1 - SubjectsTermNotLitGenreText - acids; biochemistry; calibration; concentration; experimental studies; geochemistry; laboratory studies; metal ores; metals; methods; recovery; sample preparation; soils; solubility; solution; trace metals; tungsten; tungsten ores; water DO - http://dx.doi.org/10.1016/j.talanta.2009.09.017 ER - TY - JOUR T1 - Thule Air Force Base hanger 9 and 10 permafrost degradation investigation AN - 50058173; 2010-033095 JF - ERDC/CRREL Letter Report AU - Bjella, Kevin Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 30 PB - U. S. Army Cold Regions Research and Engineering Laboratory, Hanover, NH KW - soil mechanics KW - permafrost KW - degradation KW - Arctic region KW - Thule Greenland KW - thawing KW - cold weather construction KW - Greenland KW - foundations KW - Thule Air Force Base KW - buildings KW - military facilities KW - frozen ground KW - 30:Engineering geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50058173?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/GeoRef&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=Bjella%2C+Kevin&rft.aulast=Bjella&rft.aufirst=Kevin&rft.date=2010-01-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=Thule+Air+Force+Base+hanger+9+and+10+permafrost+degradation+investigation&rft.title=Thule+Air+Force+Base+hanger+9+and+10+permafrost+degradation+investigation&rft.issn=&rft_id=info:doi/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2010-01-01 N1 - Number of references - 15 N1 - PubXState - NH N1 - Document feature - illus. N1 - Last updated - 2012-06-07 N1 - CODEN - #05693 N1 - SubjectsTermNotLitGenreText - Arctic region; buildings; cold weather construction; degradation; foundations; frozen ground; Greenland; military facilities; permafrost; soil mechanics; thawing; Thule Air Force Base; Thule Greenland ER - TY - JOUR T1 - Evaluation of a Whole-Blood Cytokine Release Assay for Use in Measuring Endotoxin Activity of Group B Neisseria meningitidis Vaccines Made from Lipid A Acylation Mutants AN - 21502101; 12492733 AB - Bacterial endotoxin interacts with the human immune system via complex immunological pathways. The evaluation of endotoxicity is important in the development of safe vaccines and immunomodulatory therapeutics. The Limulus amebocyte lysate (LAL) assay is generally accepted by the FDA for use for the quantification of lipopolysaccharide (LPS), while the rabbit pyrogen test (RPT) is used to estimate pyrogenicity during early development and production. Other in vitro assays, such as cytokine release assays with human whole blood (WB) or peripheral blood mononuclear cells (PBMCs), have also been used and may better estimate the human immunological response to products containing novel LPS molecules. In this study, WB and PBMC interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-) release assays were used to estimate the endotoxic activities of purified LPS and native outer membrane vesicle (NOMV) vaccines derived from wild-type (hexa-acylated lipid A) and genetically detoxified (penta- and tetra-acylated lipid A) group B Neisseria meningitidis. A method for quantification of the differences in endotoxicity observed in the WB and PBMC assays is elucidated. The LAL assay was shown to be relatively insensitive to lipid A variations, and the RPT was less sensitive than the cytokine release assay with WB. The IL-6 and TNF- assays with WB but not the assays with PBMCs distinguished between vaccines containing LPS from penta- and tetra-acylated strains. The high degree of sensitivity of the WB system to LPS variations and the presumed relevance of the use of human tissues to predict toxicity in humans suggest that this assay may be particularly well suited for the safety evaluation of vaccines and therapeutics containing acylation variants of LPS. JF - Clinical and Vaccine Immunology AU - Stoddard, Mark B AU - Pinto, Valerian AU - Keiser, Paul B AU - Zollinger, Wendell AD - Walter Reed Army Institute of Research, Silver Spring, Maryland, wendell.zollinger@us.army.mil Y1 - 2010/01// PY - 2010 DA - Jan 2010 SP - 98 EP - 107 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 17 IS - 1 SN - 1556-679X, 1556-679X KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Endotoxins KW - Interleukin 6 KW - Amebocytes KW - Pyrogens KW - Immune system KW - Outer membranes KW - Neisseria meningitidis KW - Toxicity KW - Acylation KW - Tumor necrosis factor-a KW - Immunomodulation KW - Pyrogenicity KW - Peripheral blood mononuclear cells KW - Membrane vesicles KW - Cytokines KW - Lipopolysaccharides KW - Lipid A KW - Immune response KW - Vaccines KW - F 06905:Vaccines KW - J 02350:Immunology KW - A 01300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21502101?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+and+Vaccine+Immunology&rft.atitle=Evaluation+of+a+Whole-Blood+Cytokine+Release+Assay+for+Use+in+Measuring+Endotoxin+Activity+of+Group+B+Neisseria+meningitidis+Vaccines+Made+from+Lipid+A+Acylation+Mutants&rft.au=Stoddard%2C+Mark+B%3BPinto%2C+Valerian%3BKeiser%2C+Paul+B%3BZollinger%2C+Wendell&rft.aulast=Stoddard&rft.aufirst=Mark&rft.date=2010-01-01&rft.volume=17&rft.issue=1&rft.spage=98&rft.isbn=&rft.btitle=&rft.title=Clinical+and+Vaccine+Immunology&rft.issn=1556679X&rft_id=info:doi/10.1128%2FCVI.00342-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2013-12-16 N1 - SubjectsTermNotLitGenreText - Amebocytes; Interleukin 6; Endotoxins; Pyrogens; Immune system; Outer membranes; Acylation; Toxicity; Tumor necrosis factor-a; Pyrogenicity; Immunomodulation; Peripheral blood mononuclear cells; Membrane vesicles; Lipopolysaccharides; Cytokines; Lipid A; Vaccines; Immune response; Neisseria meningitidis DO - http://dx.doi.org/10.1128/CVI.00342-09 ER - TY - JOUR T1 - Mortality Associated with Acinetobacter baumannii Complex Bacteremia among Patients with War-Related Trauma AN - 21495470; 12491749 AB - We investigated the mortality associated with Acinetobacter baumannii complex bacteremia among a cohort of patients hospitalized for war-related trauma. Despite a high prevalence of multidrug-resistant strains, the 30-day mortality rate was 2%. For relatively young patients with war-related trauma, A. baumannii complex bacteremia appears to be associated with a low risk of death. JF - Infection Control and Hospital Epidemiology AU - Kang, Grace AU - Hartzell, Joshua D AU - Howard, Robin AU - Wood-Morris, Robert N AU - Johnson, Mark D AU - Fraser, Susan AU - Weintrob, Amy AU - Wortmann, Glenn AD - Department of Medicine, the Infectious Diseases Service, Department of Medicine, and the Department of Clinical Investigation, Walter Reed Army Medical Center, Washington, DC., glenn.wortmann@us.army.mil Y1 - 2010 PY - 2010 DA - 2010 SP - 92 EP - 94 PB - University of Chicago Press, P.O. Box 37005 Chicago IL 60637 USA, [mailto:help@press.uchicago.edu], [URL:http://www.journals.uchicago.edu/] VL - 31 IS - 1 SN - 0899-823X, 0899-823X KW - Microbiology Abstracts B: Bacteriology; Risk Abstracts KW - Mortality KW - Acinetobacter baumannii KW - Drug resistance KW - Risk factors KW - Bacteremia KW - Trauma KW - Hospitals KW - R2 23060:Medical and environmental health KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21495470?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Infection+Control+and+Hospital+Epidemiology&rft.atitle=Mortality+Associated+with+Acinetobacter+baumannii+Complex+Bacteremia+among+Patients+with+War-Related+Trauma&rft.au=Ringelberg%2C+D%3BRichmond%2C+M%3BFoley%2C+K%3BReynolds%2C+C&rft.aulast=Ringelberg&rft.aufirst=D&rft.date=2008-07-01&rft.volume=74&rft.issue=1&rft.spage=17&rft.isbn=&rft.btitle=&rft.title=Journal+of+Microbiological+Methods&rft.issn=01677012&rft_id=info:doi/10.1016%2Fj.mimet.2007.07.007 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Mortality; Risk factors; Drug resistance; Bacteremia; Hospitals; Trauma; Acinetobacter baumannii DO - http://dx.doi.org/10.1086/649220 ER - TY - JOUR T1 - Expression of Genes Associated with Immunoproteasome Processing of Major Histocompatibility Complex Peptides Is Indicative of Protection with Adjuvanted RTS,S Malaria Vaccine AN - 21474232; 12491907 AB - Background. Patterns of expressed genes in the peripheral blood mononuclear cells of persons who were receiving RTS,S/AS01 or RTS,S/AS02 malaria vaccine and were undergoing experimental challenge with mosquito- borne falciparum malaria were examined to identify markers associated with protection. Methods. Thirty-nine vaccine recipients were assessed at study entry; on the day of the third vaccination; at 24 h, 72 h, and 2 weeks after vaccination; and on day 5 after challenge. Of 39 vaccine recipients, 13 were protected and 26 were not. Eleven vaccine recipients exhibited delayed onset of parasitemia. All infectivity control subjects developed parasitemia. Prediction analysis of microarrays identified genes corresponding with protection. Gene set enrichment analysis identified sets of genes associated with protection after the third vaccination and before challenge. Results. After the third vaccination and before challenge, differential expression of genes in the immunoproteasome pathway distinguished protected and nonprotected persons. At 5 days after challenge, differential expression of genes associated with programmed cell death distinguished between subjects protected and not protected from malaria blood-stage infection. Conclusions. The up-regulation of genes associated with the efficient processing of major histocompatibility complex peptides suggests a potential role of the vaccine in conferring major histocompatibility complex class 1-mediated protection and may represent a useful surrogate marker of vaccine efficacy without the need for challenge. JF - Journal of Infectious Diseases AU - Vahey, Maryanne T AU - Wang, Zhining AU - Kester, Kent E AU - Cummings, James AU - Heppner, DGray AU - Nau, Martin E AU - Ofori-Anyinam, Opokua AU - Cohen, Joe AU - Coche, Thierry AU - Ballou, WRipley AU - Ockenhouse, Christian F AD - The Walter Reed Army Institute of Research, Silver Spring, and The Henry M. Jackson Foundation for the Advancement of Military Medicine, Rockville, Maryland, maryanne.vahey@us.army.mil Y1 - 2010///0, PY - 2010 DA - 0, 2010 SP - 580 EP - 589 PB - University of Chicago Press, P.O. Box 37005 Chicago IL 60637 USA, [mailto:help@press.uchicago.edu], [URL:http://www.journals.uchicago.edu/] VL - 201 IS - 4 SN - 0022-1899, 0022-1899 KW - Genetics Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Microbiology Abstracts C: Algology, Mycology & Protozoology; Immunology Abstracts KW - Human diseases KW - Apoptosis KW - Disease control KW - Major histocompatibility complex KW - Malaria KW - Pest control KW - Infection KW - DNA microarrays KW - Vaccination KW - Public health KW - Gene expression KW - parasitemia KW - Peripheral blood mononuclear cells KW - Infectivity KW - Peptides KW - Vaccines KW - K 03400:Human Diseases KW - Q1 08484:Species interactions: parasites and diseases KW - G 07730:Development & Cell Cycle KW - F 06910:Microorganisms & Parasites KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21474232?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Infectious+Diseases&rft.atitle=Expression+of+Genes+Associated+with+Immunoproteasome+Processing+of+Major+Histocompatibility+Complex+Peptides+Is+Indicative+of+Protection+with+Adjuvanted+RTS%2CS+Malaria+Vaccine&rft.au=Vahey%2C+Maryanne+T%3BWang%2C+Zhining%3BKester%2C+Kent+E%3BCummings%2C+James%3BHeppner%2C+DGray%3BNau%2C+Martin+E%3BOfori-Anyinam%2C+Opokua%3BCohen%2C+Joe%3BCoche%2C+Thierry%3BBallou%2C+WRipley%3BOckenhouse%2C+Christian+F&rft.aulast=Vahey&rft.aufirst=Maryanne&rft.date=2010-01-01&rft.volume=201&rft.issue=4&rft.spage=580&rft.isbn=&rft.btitle=&rft.title=Journal+of+Infectious+Diseases&rft.issn=00221899&rft_id=info:doi/10.1086%2F650310 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2016-04-13 N1 - SubjectsTermNotLitGenreText - Gene expression; Human diseases; Disease control; Pest control; Peptides; Malaria; Vaccines; Vaccination; Public health; Infectivity; Peripheral blood mononuclear cells; parasitemia; Apoptosis; Major histocompatibility complex; Infection; DNA microarrays DO - http://dx.doi.org/10.1086/650310 ER - TY - JOUR T1 - Syphilis co-infection does not affect HIV disease progression AN - 21321183; 12340006 AB - HIV and syphilis are often seen as co-infections since they share a common mode of transmission. During episodes of syphilis, CD4 counts transiently decrease and HIV viral loads increase; however, the effect of syphilis co-infection on HIV disease progression (time to AIDS or death) is unclear. We analysed prospectively collected information on 2239 persons with estimated dates of HIV seroconversion (205 [9.2%] with confirmed syphilis and 66 [2.9%] with probable syphilis) in order to determine the effect of syphilis co-infection on HIV disease progression. In multivariate models censored at highly active antiretroviral therapy (HAART) initiation or last visit, adjusting for CD4 count, age, race, gender, and hepatitis B and C status, syphilis (confirmed + probable) was not associated with increased hazard of AIDS or death (hazard ratio 0.99, 95% CI 0.73-1.33). Treating HAART as a time-varying covariate or limiting the analysis to only confirmed syphilis cases did not significantly alter the results. Despite transient changes in CD4 counts and viral loads, syphilis does not appear to affect HIV disease progression. JF - International Journal of STD & AIDS AU - Weintrob, A C AU - Gu, W AU - Qin, J AU - Robertson, J AU - Ganeson, A AU - Crum-Cianflone, N F AU - Landrum, M L AU - Wortmann, G W AU - Follman, D AU - Agan, B K AD - 6900 Georgia Ave NW, Building 2, Ward 63, Room 6312, Washington, DC 20307, USA, Amy.Weintrob@amedd.army.mil Y1 - 2010/01// PY - 2010 DA - Jan 2010 SP - 57 EP - 59 VL - 21 IS - 1 SN - 0956-4624, 0956-4624 KW - Microbiology Abstracts B: Bacteriology; Virology & AIDS Abstracts KW - CD4 antigen KW - Acquired immune deficiency syndrome KW - Age KW - Human immunodeficiency virus KW - highly active antiretroviral therapy KW - Treponema pallidum KW - Hepatitis B KW - Seroconversion KW - Syphilis KW - Races KW - Models KW - V 22360:AIDS and HIV KW - J 02490:Miscellaneous UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21321183?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+Journal+of+STD+%26+AIDS&rft.atitle=Syphilis+co-infection+does+not+affect+HIV+disease+progression&rft.au=Weintrob%2C+A+C%3BGu%2C+W%3BQin%2C+J%3BRobertson%2C+J%3BGaneson%2C+A%3BCrum-Cianflone%2C+N+F%3BLandrum%2C+M+L%3BWortmann%2C+G+W%3BFollman%2C+D%3BAgan%2C+B+K&rft.aulast=Weintrob&rft.aufirst=A&rft.date=2010-01-01&rft.volume=21&rft.issue=1&rft.spage=57&rft.isbn=&rft.btitle=&rft.title=International+Journal+of+STD+%26+AIDS&rft.issn=09564624&rft_id=info:doi/10.1258%2Fijsa.2009.009164 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Age; Acquired immune deficiency syndrome; CD4 antigen; highly active antiretroviral therapy; Hepatitis B; Seroconversion; Syphilis; Races; Models; Human immunodeficiency virus; Treponema pallidum DO - http://dx.doi.org/10.1258/ijsa.2009.009164 ER - TY - JOUR T1 - Virulence, Inflammatory Potential, and Adaptive Immunity Induced by Shigella flexneri msbB Mutants , AN - 21293982; 12511419 AB - The ability of genetically detoxified lipopolysaccharide (LPS) to stimulate adaptive immune responses is an ongoing area of investigation with significant consequences for the development of safe and effective bacterial vaccines and adjuvants. One approach to genetic detoxification is the deletion of genes whose products modify LPS. The msbB1 and msbB2 genes, which encode late acyltransferases, were deleted in the Shigella flexneri 2a human challenge strain 2457T to evaluate the virulence, inflammatory potential, and acquired immunity induced by strains producing underacylated lipid A. Consistent with a reduced endotoxic potential, S. flexneri 2a msbB mutants were attenuated in an acute mouse pulmonary challenge model. Attenuation correlated with decreases in the production of proinflammatory cytokines and in chemokine release without significant changes in lung histopathology. The levels of specific proinflammatory cytokines (interleukin-1? [IL-1?], macrophage inflammatory protein 1 [MIP-1], and tumor necrosis factor alpha [TNF-]) were also significantly reduced after infection of mouse macrophages with either single or double msbB mutants. Surprisingly, the msbB double mutant displayed defects in the ability to invade, replicate, and spread within epithelial cells. Complementation restored these phenotypes, but the exact nature of the defects was not determined. Acquired immunity and protective efficacy were also assayed in the mouse lung model, using a vaccination-challenge study. Both humoral and cellular responses were generally robust in msbB-immunized mice and afforded significant protection from lethal challenge. These data suggest that the loss of either msbB gene reduces the endotoxicity of Shigella LPS but does not coincide with a reduction in protective immune responses. JF - Infection and Immunity AU - Ranallo, Ryan T AU - Kaminski, Robert W AU - George, Tonia AU - Kordis, Alexis A AU - Chen, Qing AU - Szabo, Kathleen AU - Venkatesan, Malabi M AD - Division of Bacterial and Rickettsial Diseases, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, ryan.ranallo@amedd.army.mil Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 400 EP - 412 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 78 IS - 1 SN - 0019-9567, 0019-9567 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Detoxification KW - Macrophages KW - Epithelial cells KW - Chemokines KW - Interleukin 1 KW - Animal models KW - Disease control KW - Histopathology KW - Adjuvants KW - Infection KW - Phenotypes KW - Virulence KW - Complementation KW - Lipopolysaccharides KW - Data processing KW - macrophage inflammatory protein 1 KW - Immunity KW - Tumor necrosis factor-a KW - Inflammation KW - Lung KW - Acyltransferase KW - Shigella flexneri KW - Lungs KW - Lipid A KW - Immune response KW - Vaccines KW - A 01490:Miscellaneous KW - Q1 08484:Species interactions: parasites and diseases KW - J 02350:Immunology KW - F 06910:Microorganisms & Parasites KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21293982?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Infection+and+Immunity&rft.atitle=Virulence%2C+Inflammatory+Potential%2C+and+Adaptive+Immunity+Induced+by+Shigella+flexneri+msbB+Mutants+%2C&rft.au=Ranallo%2C+Ryan+T%3BKaminski%2C+Robert+W%3BGeorge%2C+Tonia%3BKordis%2C+Alexis+A%3BChen%2C+Qing%3BSzabo%2C+Kathleen%3BVenkatesan%2C+Malabi+M&rft.aulast=Ranallo&rft.aufirst=Ryan&rft.date=2010-01-01&rft.volume=78&rft.issue=1&rft.spage=400&rft.isbn=&rft.btitle=&rft.title=Infection+and+Immunity&rft.issn=00199567&rft_id=info:doi/10.1128%2FIAI.00533-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2016-10-26 N1 - SubjectsTermNotLitGenreText - Macrophages; Virulence; Disease control; Histopathology; Lungs; Vaccines; Immunity; Phenotypes; Detoxification; Epithelial cells; Chemokines; Data processing; macrophage inflammatory protein 1; Interleukin 1; Animal models; Adjuvants; Tumor necrosis factor-a; Infection; Inflammation; Complementation; Acyltransferase; Lung; Lipopolysaccharides; Lipid A; Immune response; Shigella flexneri DO - http://dx.doi.org/10.1128/IAI.00533-09 ER - TY - JOUR T1 - Nitrogen retention in a floodplain backwater of the upper Mississippi River (USA) AN - 21264149; 11833615 AB - Backwaters connected to large rivers retain nitrate and may play an important role in reducing downstream loading to coastal marine environments. A summer nitrogen (N) inflow-outflow budget was examined for a flow-regulated backwater of the upper Mississippi River in conjunction with laboratory estimates of sediment ammonium and nitrate fluxes, organic N mineralization, nitrification, and denitrification to provide further insight into N retention processes. External N loading was overwhelmingly dominated by nitrate and 54% of the input was retained (137mgm super(-2) day super(-1)). Ammonium and dissolved organic N were exported from the backwater (14 and 9mgm super(-2)day super(-1), respectively). Nitrate influx to sediment increased as a function of increasing initial nitrate concentration in the overlying water. Rates were greater under anoxic versus oxic conditions. Ammonium effluxes from sediment were 26.7 and 50.6mgm super(-2) day super(-1) under oxic and anoxic conditions, respectively. Since anoxia inhibited nitrification, the difference between ammonium anoxic-oxic fluxes approximated a nitrification rate of 29.1mgm super(-2) day super(-1). Organic N mineralization was 64mgm super(-2)da y super(-1). Denitrification, estimated from regression relationships between oxic nitrate influx versus initial nitrate concentration and a summer lakewide mean nitrate concentration of 1.27mgl super(-1), was 94mgm super(-2)da y super(-1). Denitrification was equivalent to only 57% of the retained nitrate, suggesting that another portion was assimilated by biota. The high sediment organic N mineralization and ammonium efflux rate coupled with the occurrence of ammonium export from the system suggested a possible link between biotic assimilation of nitrate, mineralization, and export. JF - Aquatic Sciences AU - James, William F AD - U.S. Army Corps of Engineers, Engineer Research and Development Center, Eau Galle Aquatic Ecology Laboratory, W500 Eau Galle Dam Road, Spring Valley, WI, 54767, USA, william.f.james@usace.army.mil Y1 - 2010/01// PY - 2010 DA - Jan 2010 SP - 61 EP - 69 PB - Springer-Verlag (Heidelberg), Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 72 IS - 1 SN - 1015-1621, 1015-1621 KW - Water Resources Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Ecology Abstracts KW - Nitrate KW - Backwater KW - Backwaters KW - Freshwater KW - Mineralization KW - Denitrification KW - Sediment Contamination KW - Sediment transport KW - Rivers KW - Ammonium KW - Sediment chemistry KW - Nitrates KW - Sediments KW - Anoxia KW - Anoxic sediments KW - North America, Mississippi R. KW - Flood plains KW - Nitrification KW - Nitrogen KW - Q2 09187:Geochemistry of sediments KW - D 04040:Ecosystem and Ecology Studies KW - SW 7060:Research facilities UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21264149?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aquatic+Sciences&rft.atitle=Nitrogen+retention+in+a+floodplain+backwater+of+the+upper+Mississippi+River+%28USA%29&rft.au=James%2C+William+F&rft.aulast=James&rft.aufirst=William&rft.date=2010-01-01&rft.volume=72&rft.issue=1&rft.spage=61&rft.isbn=&rft.btitle=&rft.title=Aquatic+Sciences&rft.issn=10151621&rft_id=info:doi/10.1007%2Fs00027-009-0113-3 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - Last updated - 2015-08-19 N1 - SubjectsTermNotLitGenreText - Anoxic sediments; Rivers; Sediment chemistry; Flood plains; Nitrification; Backwaters; Sediment transport; Mineralization; Ammonium; Nitrate; Denitrification; Sediments; Anoxia; Nitrogen; Backwater; Nitrates; Sediment Contamination; North America, Mississippi R.; Freshwater DO - http://dx.doi.org/10.1007/s00027-009-0113-3 ER - TY - JOUR T1 - Electrocoagulation pretreatment of seawater prior to ultrafiltration: Pilot-scale applications for military water purification systems AN - 1777110351; 11323206 AB - The objectives were to investigate the performance of a pilot-scale electrocoagulation (EC) reactor and to determine the feasibility of using in-line EC as a pretreatment to ultrafiltration (UF) of seawater. Work was conducted at Port Hueneme, CA, using components of a U.S. military water purification system. Ferric chloride in-line coagulation was also tested. Both the EC and ferric chloride pretreatments improved UF membrane performance compared to UF without in-line coagulation. EC resulted in slightly greater increases in transmembrane pressure (TMP) than observed following ferric chloride pretreatment during sub-critical flux UF. Substantial accumulation of precipitates developed on the EC electrodes during the testing period. X-ray diffraction identified magnetite, maghemite, lepidocrocite, and akaganeite phases. Accumulation of these precipitates was due in part to conservative hydraulic design of the EC unit. It is recommended that EC units should be designed with short hydraulic retention times and higher electrode current density in order to increase upflow (scour) velocity and thus inhibit accumulation on the electrodes. Progressively longer cycling times for polarity reversal are also recommended. This research indicates that EC offers the potential for a feasible and effective pretreatment strategy for mobile water production facilities. JF - Desalination AU - Timmes, T C AU - Kim, H C AU - Dempsey, BA AD - Pennsylvania State University, University Park, PA 16802, USA Thomas.timmes@us.army.mil Y1 - 2010/01/01/ PY - 2010 DA - 2010 Jan 01 SP - 6 EP - 13 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 250 IS - 1 SN - 0011-9164, 0011-9164 KW - Environmental Engineering Abstracts (EN); CSA / ASCE Civil Engineering Abstracts (CE) KW - Ultrafiltration KW - Ferric chloride KW - Sea water KW - Pretreatment KW - Electrodes KW - Precipitates KW - Water purification KW - Electrocoagulation KW - Marine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1777110351?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvironmentalengabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Desalination&rft.atitle=Electrocoagulation+pretreatment+of+seawater+prior+to+ultrafiltration%3A+Pilot-scale+applications+for+military+water+purification+systems&rft.au=Timmes%2C+T+C%3BKim%2C+H+C%3BDempsey%2C+BA&rft.aulast=Timmes&rft.aufirst=T&rft.date=2010-01-01&rft.volume=250&rft.issue=1&rft.spage=6&rft.isbn=&rft.btitle=&rft.title=Desalination&rft.issn=00119164&rft_id=info:doi/10.1016%2Fj.desal.2009.03.021 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2016-05-18 N1 - SubjectsTermNotLitGenreText - Marine DO - http://dx.doi.org/10.1016/j.desal.2009.03.021 ER - TY - JOUR T1 - Geointerpretative opportunities foster learning outside the classroom AN - 1756505163; 2016-007030 AB - Field trips have long been a part of school activities, learning, and curriculum. The application of interpretive techniques or the interpretive approach can further enhance learning and retention in outside the classroom opportunities. This is especially true when exploring geographic or geologic concepts. This article explores the concept of interpretation and provides an example of an interpretive opportunity developed for local schools. Recommendations on how to develop an effective interpretive program are discussed. JF - Journal of Geography AU - Thompson, Wiley C Y1 - 2010 PY - 2010 DA - 2010 SP - 124 EP - 129 PB - Routledge for the National Council for Geographic Education, Indiana, PA VL - 109 IS - 3 SN - 0022-1341, 0022-1341 KW - geology KW - programs KW - educational resources KW - K-12 education KW - geography KW - curricula KW - field trips KW - interpretation KW - education KW - concepts KW - 15:Miscellaneous UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1756505163?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Geography&rft.atitle=Geointerpretative+opportunities+foster+learning+outside+the+classroom&rft.au=Thompson%2C+Wiley+C&rft.aulast=Thompson&rft.aufirst=Wiley&rft.date=2010-01-01&rft.volume=109&rft.issue=3&rft.spage=124&rft.isbn=&rft.btitle=&rft.title=Journal+of+Geography&rft.issn=00221341&rft_id=info:doi/10.1080%2F00221341.2010.485549 L2 - http://www.informaworld.com/smpp/title~db=all~content=t770943818 LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2016, American Geosciences Institute. N1 - Date revised - 2016-01-01 N1 - PubXState - PA N1 - SuppNotes - Based on Publisher-supplied data N1 - Last updated - 2016-01-14 N1 - CODEN - JOGGA9 N1 - SubjectsTermNotLitGenreText - concepts; curricula; education; educational resources; field trips; geography; geology; interpretation; K-12 education; programs DO - http://dx.doi.org/10.1080/00221341.2010.485549 ER - TY - JOUR T1 - Full-Scale Field Testing for Injected Foam Stabilization of Portland Cement Concrete Repairs AN - 1671234469; 14128556 AB - A series of foam-injected repairs was performed on a portland cement concrete (PCC) test section at the U. S. Army Engineer Research and Development Center. Repairs consisted of uncompacted backfill overlaid by a 9-in. rapid-setting cementitious cap. A series of injection tubes was inserted through the cap into the uncompacted debris backfill, and a two-component rigid polyurethane foam was injected into this backfill. The test matrix compared the performance of three different repairs using various volumes of injected foam. Afourth repair was constructed without injected foam as a control item. Three hours after cap construction, the repairs underwent simulated aircraft traffic with an F-15E load cart. The performance of the four repairs was measured by passes to failure. The results of traffic testing were used to evaluate foam-injection technology for rapid repair of PCC pavements. The performances of foaminjected repairs were also compared with poured foam and traditional full-depth backfill repairs, each capped with rapid-setting materials. Comparisons were made about pavement performance, costs, and total duration required for installing the repair. Results showed that injection of excessive foam was detrimental to the repair surface, because it induced cracking before traffic application, and could lead to premature development of foreign object damage. However, repairs using moderate amounts of foam and pure backfill sustained the required traffic levels, defined by the research sponsor, of 200 passes within 4 h of initiating the pavement repair. For cost and repair duration, those repairs that did not include foam were more effective. Show References JF - Transportation Research Record AU - Priddy, Lucy P AU - Jersey, Sarah R AU - Reese, Cody M AD - U. S. Army Engineer Research and Development Center, 3909 Halls Ferry Road, Vicksburg, MS 39180 Y1 - 2010 PY - 2010 DA - 2010 SP - 24 EP - 33 PB - Transportation Research Board VL - 2155 SN - 0361-1981, 0361-1981 KW - Ceramic Abstracts/World Ceramics Abstracts (WC); Environmental Engineering Abstracts (EN); CSA / ASCE Civil Engineering Abstracts (CE) KW - Costs KW - Pavements KW - Portland cements KW - Traffic flow KW - Backfill KW - Traffic engineering KW - Foams KW - Repairing KW - Maintenance UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1671234469?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvironmentalengabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Transportation+Research+Record&rft.atitle=Full-Scale+Field+Testing+for+Injected+Foam+Stabilization+of+Portland+Cement+Concrete+Repairs&rft.au=Priddy%2C+Lucy+P%3BJersey%2C+Sarah+R%3BReese%2C+Cody+M&rft.aulast=Priddy&rft.aufirst=Lucy&rft.date=2010-01-01&rft.volume=2155&rft.issue=&rft.spage=24&rft.isbn=&rft.btitle=&rft.title=Transportation+Research+Record&rft.issn=03611981&rft_id=info:doi/10.3141%2F2155-03 L2 - http://trb.metapress.com/content/r0v64lrw55310756/?p=803b163fc894430e9751214d02d7cb79&pi=2 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-03-01 N1 - Last updated - 2015-04-09 DO - http://dx.doi.org/10.3141/2155-03 ER - TY - JOUR T1 - Modeling Erosion of an Unlined Spillway Chute Cut in Rock AN - 1551634995; 14218788 AB - Discharges up to 1700 m super(3)/s that lasted 21 days caused extensive erosion of the spillway chute excavated in rock at Tuttle Creek Lake, Kansas. Nearly 300 000 m3 of shale and limestone were eroded from the unlined chute resulting in a series of escarpments ranging in height from 1.20 to about 8 m. An empirical mathematical model, similar to a US Department of Agriculture model was developed for geologic conditions at Tuttle Creek Lake. This site specific model was used to evaluate the extent of erosion anticipated for future events and, based on this evaluation, to design the spillway repair. The model provides conservative results since it was conceived in such a manner as to over predict erosion. Initial attempts to generalize its use provided questionable results, but similar site specific procedures may be used in other locations for future events. AU - Perlea, Vlad AU - Mathews, David AU - Walberg, Francke AD - U.S. Army Corps of Engineers, Sacramento District, 1325 J Street, Sacramento, CA 95814. Y1 - 2010///0, PY - 2010 DA - 0, 2010 SP - 530 EP - 539 KW - Aqualine Abstracts; Water Resources Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources KW - Erosion KW - Spillways KW - Rocks KW - Kansas KW - Limestone KW - Soil erosion KW - Streams KW - Evaluation KW - Lakes KW - Modelling KW - Mathematical models KW - USA, Kansas KW - Creek KW - Model Studies KW - Escarpments KW - Chutes KW - AQ 00001:Water Resources and Supplies KW - SW 6010:Structures KW - Q2 09124:Coastal zone management UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1551634995?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=&rft.atitle=Modeling+Erosion+of+an+Unlined+Spillway+Chute+Cut+in+Rock&rft.au=Perlea%2C+Vlad%3BMathews%2C+David%3BWalberg%2C+Francke&rft.aulast=Perlea&rft.aufirst=Vlad&rft.date=2010-01-01&rft.volume=&rft.issue=&rft.spage=530&rft.isbn=9780784411476&rft.btitle=&rft.title=&rft.issn=&rft_id=info:doi/10.1061%2F41147%28392%2951 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2014-08-01 N1 - Last updated - 2017-02-01 N1 - SubjectsTermNotLitGenreText - Mathematical models; Escarpments; Soil erosion; Creek; Modelling; Evaluation; Lakes; Erosion; Limestone; Rocks; Spillways; Chutes; Streams; Model Studies; USA, Kansas DO - http://dx.doi.org/10.1061/41147(392)51 ER - TY - JOUR T1 - Processes effecting sediment transfer across the land-sea interface and resulting shelf stratigraphy AN - 1549619000; 2014-056640 AB - The land-sea interface is a sensitive, dynamic filter that modulates the transfer of sediment from terrestrial to marine environments. The degree of filtering is a function of the complex interactions between sediment supply, sea level, physical energy and tectonics. Understanding the processes influencing the efficiency of sediment segregation at this interface will yield insight on the processes that create stratigraphy on adjacent continental shelves. We present examples of two land-sea interfaces from tectonically active, regressive settings on the North Island of New Zealand: (1) the inner shelf off of the Waiapu River, and (2) Poverty Bay, adjacent to the Waipaoa River. An extensive array of geophysical, sedimentological, and hydrodynamic data are used to quantitatively assess the efficiency of sediment segregation, deposition, and subsequent resuspension and off-shore transport at the land-sea interface. The two systems share several similarities with regards to the processes controlling the efficiency of the land-sea filter, including sea level, physical energy and tectonics. Results from Poverty Bay indicate that while the system is occasionally overwhelmed by fine-grained sediment deposition resulting in the preservation of event beds near the surface, more often the system efficiently segregates sediment, preserving little fine-grained sediment. Both long-term floodplain stratigraphy and stratigraphic models indicate this has been the case for the Waipaoa system for the last several thousand years, despite a recent 4-5 fold increase in sediment supply. In contrast, results from the Waiapu show a shift from efficient to inefficient sediment segregation at the land-sea interface over the same time-frame, with significant modern capture of fine-grained material primarily as event layers on the inner shelf (16-34% of the modern, fine-grained budget). This suggests that in Poverty Bay, an increase in sediment supply has been modulated by the other filtering processes, resulting in consistently efficient segregation and bypassing. Conversely, on the Waiapu inner shelf, the increase in sediment supply has overwhelmed the modulating effects of the other processes, changing the behavior of the land-sea filter and thus altering the type of stratigraphy formed. The influence of these differing filters is evaluated in the context of the effects on the stratigraphy farther offshore, where preservation over the long-term is more likely to occur. JF - Abstracts: Annual Meeting - American Association of Petroleum Geologists AU - Wadman, Heidi M AU - McNinch, Jesse E AU - Anonymous Y1 - 2010 PY - 2010 DA - 2010 PB - American Association of Petroleum Geologists and Society for Sedimentary Geology, Tulsa, OK VL - 2010 KW - segregation KW - lithostratigraphy KW - Australasia KW - sediment transport KW - grain size KW - sedimentation KW - sediment supply KW - nearshore sedimentation KW - Waiapu River KW - North Island KW - transport KW - Poverty Bay KW - inner shelf KW - sorting KW - coastal environment KW - depositional environment KW - continental shelf KW - New Zealand KW - 06A:Sedimentary petrology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1549619000?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Abstracts%3A+Annual+Meeting+-+American+Association+of+Petroleum+Geologists&rft.atitle=Processes+effecting+sediment+transfer+across+the+land-sea+interface+and+resulting+shelf+stratigraphy&rft.au=Wadman%2C+Heidi+M%3BMcNinch%2C+Jesse+E%3BAnonymous&rft.aulast=Wadman&rft.aufirst=Heidi&rft.date=2010-01-01&rft.volume=2010&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Abstracts%3A+Annual+Meeting+-+American+Association+of+Petroleum+Geologists&rft.issn=&rft_id=info:doi/ L2 - http://www.searchanddiscovery.com/abstracts/pdf/2010/annual/abstracts/ndx_wadman.pdf LA - English DB - GeoRef N1 - Conference title - AAPG 2010 annual convention & exhibition N1 - Copyright - GeoRef, Copyright 2014, American Geosciences Institute. Reference includes data supplied by American Association of Petroleum Geologists, Tulsa, OK, United States N1 - Date revised - 2014-01-01 N1 - PubXState - OK N1 - Last updated - 2014-07-31 N1 - CODEN - #06983 N1 - SubjectsTermNotLitGenreText - Australasia; coastal environment; continental shelf; depositional environment; grain size; inner shelf; lithostratigraphy; nearshore sedimentation; New Zealand; North Island; Poverty Bay; sediment supply; sediment transport; sedimentation; segregation; sorting; transport; Waiapu River ER - TY - JOUR T1 - A Watershed Modeling Tool, HEC-WAT AN - 1430857661; 14142179 AB - For the past few years, the U.S. Army Corps of Engineers' Institute for Water Resources, Hydrologic Engineering Center (CEIWR-HEC) has been developing the Watershed Analysis Tool (HEC-WAT). This software was created to help Project Delivery Teams (PDT's) conduct watershed and water resources studies in an integrated, comprehensive and systems based analyses. The degree of coordination across disciplines, offices and agencies, for these complex studies is often difficult to complete. The PDT must come to a consensus on the definition of the problems, issues, and opportunities and continue with the definition of the various models, events and analyses to determine impacts so that appropriate decisions may be made. This paper will discuss the development, features and capabilities of HEC-WAT and will also document several applications. In addition, a new feature will be discussed that will eventually allow HEC-WAT to run a Monte Carlo analyses so that a robust risk analysis can be performed. JF - Watershed Management 2010: Innovations in Watershed Management under Land Use and Climate Change AU - Dunn, Christopher N AU - Baker, Penni R AD - Director, U.S. Army Corps of Engineers, Institute for Water Resources, Hydrologic Engineering Center, 609 Second Street, Davis, CA 95616. Y1 - 2010///0, PY - 2010 DA - 0, 2010 SP - 1101 EP - 1112 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Aqualine Abstracts; Water Resources Abstracts KW - Watersheds KW - Hydrologic models KW - Monte Carlo method KW - Land Use KW - Resource management KW - Climate change KW - Statistical analysis KW - Water resources KW - Watershed Management KW - Freshwater KW - Engineering KW - Hydrologic Models KW - River basin management KW - Modelling KW - Land use KW - Risk KW - USA KW - Resource development KW - Water Resources KW - SW 5010:Network design KW - Q5 08503:Characteristics, behavior and fate KW - AQ 00007:Industrial Effluents UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1430857661?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Watershed+Management+2010%3A+Innovations+in+Watershed+Management+under+Land+Use+and+Climate+Change&rft.atitle=A+Watershed+Modeling+Tool%2C+HEC-WAT&rft.au=Dunn%2C+Christopher+N%3BBaker%2C+Penni+R&rft.aulast=Dunn&rft.aufirst=Christopher&rft.date=2010-01-01&rft.volume=&rft.issue=&rft.spage=1101&rft.isbn=9780784411438&rft.btitle=&rft.title=Watershed+Management+2010%3A+Innovations+in+Watershed+Management+under+Land+Use+and+Climate+Change&rft.issn=&rft_id=info:doi/10.1061%2F41148%28389%2999 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-09-01 N1 - Last updated - 2017-02-01 N1 - SubjectsTermNotLitGenreText - Resource management; Climate change; Statistical analysis; Water resources; Resource development; Watersheds; River basin management; Land use; Modelling; Land Use; Risk; Engineering; Hydrologic Models; Watershed Management; Water Resources; USA; Freshwater DO - http://dx.doi.org/10.1061/41148(389)99 ER - TY - JOUR T1 - Multi-Objective Management and Planning for Urban Watersheds AN - 1430851989; 14142144 AB - Cumulative impacts and losses occur in watersheds as humans develop them. Cumulative losses to the environment occur, and cumulative impacts occur to constituents in the downstream part of the watersheds in terms of flood hazards. The paper reviews how multi-objective management is fundamental to urban watershed management and can address cumulative effects from development. The paper encourages the use of incentives and established processes to address the cumulative effects, specifically both the basic technical and organizational processes for developing urban watershed planning. Technical processes for watershed environmental planning are introduced for comparing green solutions, including best management practices and stream corridor rehabilitation. The paper demonstrates how habitat units may be used to maximize the net benefits for multipurpose projects. The basic steps for these processes clarify watershed planning work and strengthen collaboration, which is part of building strong partnerships in our Nation's watersheds. JF - Watershed Management 2010: Innovations in Watershed Management under Land Use and Climate Change AU - Rast, Brian AD - Member American Society of Civil Engineers (ASCE) and Association of State Floodplain Managers (ASFPM), Planning Branch, U.S. Army Corps of Engineers, Kansas City District, Richard Bolling Federal Building, Suite 529, 601 East 12 super(th) Street, Kansas City, Missouri 64106-2896. Y1 - 2010///0, PY - 2010 DA - 0, 2010 SP - 702 EP - 720 KW - ASFA 3: Aquatic Pollution & Environmental Quality; Aqualine Abstracts; Water Resources Abstracts KW - Urban areas KW - Watersheds KW - Stormwater management KW - Urban Watersheds KW - Resource management KW - Climate change KW - Watershed Management KW - Freshwater KW - Streams KW - Environmental factors KW - Floods KW - Planning KW - Downstream KW - Corridor KW - River basin management KW - Rehabilitation KW - Land use KW - Stream KW - National planning KW - SW 5010:Network design KW - AQ 00006:Sewage KW - Q5 08505:Prevention and control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1430851989?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Microbiology&rft.atitle=Wet+and+dry+density+of+Bacillus+anthracis+and+other+Bacillus+species&rft.au=Carrera%2C+M%3BZandomeni%2C+RO%3BSagripanti%2C+J-L&rft.aulast=Carrera&rft.aufirst=M&rft.date=2008-07-01&rft.volume=105&rft.issue=1&rft.spage=68&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Microbiology&rft.issn=13645072&rft_id=info:doi/10.1111%2Fj.1365-2672.2008.03758.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2013-09-01 N1 - Last updated - 2017-02-01 N1 - SubjectsTermNotLitGenreText - Resource management; Stream; Climate change; Corridor; Watersheds; Environmental factors; River basin management; Land use; National planning; Urban Watersheds; Rehabilitation; Floods; Planning; Downstream; Watershed Management; Streams; Freshwater DO - http://dx.doi.org/10.1061/41148(389)64 ER - TY - JOUR T1 - Watershed Study of the Iowa-Cedar River Basin AN - 1093462037; 14142177 AB - Historic flooding within the Iowa-Cedar River Basin, in 2008, has emphasized the need for an integrated approach to watershed-based planning and management of the basin. This paper provides a description of the emerging watershed study currently being developed by the Rock Island District, Corps of Engineers in cooperation with the state of Iowa, local governments, and private organizations. The purpose of the Corps planning study effort is to formulate a comprehensive watershed plan and process for interagency collaboration to address water resource and related land resource problems and opportunities in the Iowa - Cedar River Basin in the interests of increasing social and economic value, increasing ecological integrity, and managing future flood risk. JF - Watershed Management 2010: Innovations in Watershed Management under Land Use and Climate Change AU - Landwehr, Kevin J AD - U.S. Army Corps of Engineers, Rock Island District, P.O. Box 2004, Rock Island, IL 61204-2004 Y1 - 2010///0, PY - 2010 DA - 0, 2010 SP - 1078 EP - 1088 KW - Aqualine Abstracts; Water Resources Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources KW - Watersheds KW - River basins KW - Iowa KW - River Basins KW - Resource management KW - Local Governments KW - Water resources KW - Freshwater KW - Land Resources KW - Floods KW - Planning KW - Regional planning KW - River basin management KW - Risk KW - USA, Iowa KW - Water management KW - USA, Iowa, Cedar R. KW - Flooding KW - National planning KW - Water Resources KW - AQ 00006:Sewage KW - SW 4020:Evaluation process KW - Q2 09124:Coastal zone management UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1093462037?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Watershed+Management+2010%3A+Innovations+in+Watershed+Management+under+Land+Use+and+Climate+Change&rft.atitle=Watershed+Study+of+the+Iowa-Cedar+River+Basin&rft.au=Landwehr%2C+Kevin+J&rft.aulast=Landwehr&rft.aufirst=Kevin&rft.date=2010-01-01&rft.volume=&rft.issue=&rft.spage=1078&rft.isbn=9780784411438&rft.btitle=&rft.title=Watershed+Management+2010%3A+Innovations+in+Watershed+Management+under+Land+Use+and+Climate+Change&rft.issn=&rft_id=info:doi/10.1061%2F41148%28389%2997 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-10-01 N1 - Last updated - 2017-02-01 N1 - SubjectsTermNotLitGenreText - Resource management; Water management; Flooding; Water resources; Regional planning; River basins; Watersheds; River basin management; National planning; Land Resources; Risk; River Basins; Local Governments; Floods; Planning; Water Resources; USA, Iowa; USA, Iowa, Cedar R.; Freshwater DO - http://dx.doi.org/10.1061/41148(389)97 ER - TY - JOUR T1 - Navigation, Flood Risk Management, and Mississippi River Ecosystem Rehabilitation AN - 1093461990; 14142119 AB - The Mississippi River is one of the world's great rivers and is the only river in the United States to be formally recognized by Congress as both a nationally significant ecosystem and commercial navigation system. The river has a long and colorful history and has played a significant role in shaping the region's social and economic development. However, the Mississippi River is not a single homogeneous unit. From its source in northern Minnesota to the Gulf of Mexico one can identify at least five distinct Mississippi Rivers based on geomorphology and hydraulics. Concomitant with these differences in the river are variations in navigation and flood risk management that result in divergent river management strategies. Levees, reservoirs, floodways, pools and locks are some of the different structures that are in place on various reaches of the river to address the concerns of flood risk management and navigation. The effects of river regulation, floodplain development and watershed modifications present constant challenges to ecosystem rehabilitation along the Mississippi River. Consequently, floodplain and wetland restoration must be developed within the context of the potentially different directions that navigation and flood management have taken the river. Because the Mississippi system varies widely in hydraulics and hydrology from source to the Gulf, ecosystem rehabilitation likewise takes different forms in different regions along the river. Moreover, the goals, targets and metrics of river rehabilitation are not constant across the entire river system. JF - Watershed Management 2010: Innovations in Watershed Management under Land Use and Climate Change AU - DuBowy, Paul J AD - Mississippi River and Tributaries Regional Technical Center, Mississippi Valley Division, U.S. Army Corps of Engineers, CEMVD-PD-WM, Vicksburg, MS 39181. Y1 - 2010///0, PY - 2010 DA - 0, 2010 SP - 431 EP - 442 KW - Aqualine Abstracts; Water Resources Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources KW - Navigation KW - Flood plains KW - Risk management KW - Mississippi River KW - Ecosystems KW - Rehabilitation KW - Hydraulics KW - Resource management KW - Freshwater KW - Gulfs KW - Risks KW - Geomorphology KW - Floods KW - Wetlands KW - River basin management KW - Rivers KW - Fluvial morphology KW - USA, Indiana, Great R. KW - USA, Minnesota KW - ASW, Mexico Gulf KW - Flood Plains KW - Risk KW - North America, Mississippi R. KW - AQ 00001:Water Resources and Supplies KW - Q2 09123:Conservation KW - SW 6010:Structures UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1093461990?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Watershed+Management+2010%3A+Innovations+in+Watershed+Management+under+Land+Use+and+Climate+Change&rft.atitle=Navigation%2C+Flood+Risk+Management%2C+and+Mississippi+River+Ecosystem+Rehabilitation&rft.au=DuBowy%2C+Paul+J&rft.aulast=DuBowy&rft.aufirst=Paul&rft.date=2010-01-01&rft.volume=&rft.issue=&rft.spage=431&rft.isbn=9780784411438&rft.btitle=&rft.title=Watershed+Management+2010%3A+Innovations+in+Watershed+Management+under+Land+Use+and+Climate+Change&rft.issn=&rft_id=info:doi/10.1061%2F41148%28389%2939 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-10-01 N1 - Last updated - 2017-02-01 N1 - SubjectsTermNotLitGenreText - Fluvial morphology; Resource management; Geomorphology; Flood plains; Floods; Wetlands; Navigation; River basin management; Risks; Flood Plains; Rivers; Hydraulics; Risk; Ecosystems; Rehabilitation; Gulfs; ASW, Mexico Gulf; North America, Mississippi R.; USA, Indiana, Great R.; USA, Minnesota; Freshwater DO - http://dx.doi.org/10.1061/41148(389)39 ER - TY - JOUR T1 - Limits of wave runup and corresponding beach-profile change from large-scale laboratory data AN - 1030489932; 2012-068603 JF - Journal of Coastal Research AU - Roberts, Tiffany M AU - Wang, Ping AU - Kraus, Nicholas C Y1 - 2010/01// PY - 2010 DA - January 2010 SP - 184 EP - 198 PB - Coastal Education and Research Foundation (CERF), Fort Lauderdale, FL VL - 26 IS - 1 SN - 0749-0208, 0749-0208 KW - experimental studies KW - landform evolution KW - analog simulation KW - prediction KW - mathematical models KW - altimetry KW - physical models KW - variations KW - observations KW - laboratory studies KW - beaches KW - ocean waves KW - beach profiles KW - geomorphology KW - 23:Geomorphology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1030489932?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Coastal+Research&rft.atitle=Limits+of+wave+runup+and+corresponding+beach-profile+change+from+large-scale+laboratory+data&rft.au=Roberts%2C+Tiffany+M%3BWang%2C+Ping%3BKraus%2C+Nicholas+C&rft.aulast=Roberts&rft.aufirst=Tiffany&rft.date=2010-01-01&rft.volume=26&rft.issue=1&rft.spage=184&rft.isbn=&rft.btitle=&rft.title=Journal+of+Coastal+Research&rft.issn=07490208&rft_id=info:doi/10.2112%2F08-1097.1 LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2012-01-01 N1 - Number of references - 43 N1 - PubXState - FL N1 - Document feature - illus. incl. 3 tables N1 - Last updated - 2012-08-02 N1 - SubjectsTermNotLitGenreText - altimetry; analog simulation; beach profiles; beaches; experimental studies; geomorphology; laboratory studies; landform evolution; mathematical models; observations; ocean waves; physical models; prediction; variations DO - http://dx.doi.org/10.2112/08-1097.1 ER - TY - JOUR T1 - Dry and wet deposition of reduced nitrogen to the Tampa Bay Watershed AN - 1020539566; 2012-057414 JF - Geochimica et Cosmochimica Acta AU - Myles, Latoya AU - Robinson, Larry AU - Anonymous Y1 - 2010 PY - 2010 DA - 2010 SP - 1 PB - Elsevier, New York, NY VL - 74 IS - 12, Suppl. 1 SN - 0016-7037, 0016-7037 KW - United States KW - hydrology KW - North America KW - monitoring KW - Pinellas County Florida KW - ammonium ion KW - watersheds KW - Tampa Bay KW - atmosphere KW - atmospheric precipitation KW - turbulence KW - Gulf Coastal Plain KW - Florida KW - nitrogen KW - measurement KW - Hillsborough County Florida KW - marine environment KW - aerosols KW - geochemistry KW - ammonia compound KW - 02B:Hydrochemistry KW - 21:Hydrogeology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1020539566?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Geochimica+et+Cosmochimica+Acta&rft.atitle=Dry+and+wet+deposition+of+reduced+nitrogen+to+the+Tampa+Bay+Watershed&rft.au=Myles%2C+Latoya%3BRobinson%2C+Larry%3BAnonymous&rft.aulast=Myles&rft.aufirst=Latoya&rft.date=2010-01-01&rft.volume=74&rft.issue=12%2C+Suppl.+1&rft.spage=A742&rft.isbn=&rft.btitle=&rft.title=Geochimica+et+Cosmochimica+Acta&rft.issn=00167037&rft_id=info:doi/ L2 - http://goldschmidt.info/2010/abstracts/A-Z+Index.pdf http://www.sciencedirect.com/science/journal/00167037 LA - English DB - GeoRef N1 - Conference title - 20th annual V. M. Goldschmidt conference N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2012-01-01 N1 - Number of references - 2 N1 - PubXState - NY N1 - Last updated - 2012-06-15 N1 - SubjectsTermNotLitGenreText - aerosols; ammonia compound; ammonium ion; atmosphere; atmospheric precipitation; Florida; geochemistry; Gulf Coastal Plain; Hillsborough County Florida; hydrology; marine environment; measurement; monitoring; nitrogen; North America; Pinellas County Florida; Tampa Bay; turbulence; United States; watersheds ER - TY - JOUR T1 - Fish Passage Restoration and the NEPA Process: Balancing Environmental Considerations with Historical and Cultural Resources AN - 1014098213; 14142115 AB - Restoration of fish passage along our rivers and streams can improve the overall aquatic habitat and environmental conditions of our waterways by allowing migration and spawning of species currently blocked by dams. Fish passage can enhance the overall productivity of ecosystems by enabling anadromous fish to return to their previous spawning grounds. This, in turn, increases the system's food supply web for resident and migratory fish. Perhaps the most effective method of restoring fish passage is to remove the stream impediment and restore the channel to natural conditions. However, existing conditions such as the historical and cultural aspects of the dam, the chemical composition of built-up sediment behind the dam, and the potential for increased downstream flood hazard risk may influence the selection of a recommended plan. Restoring environmental balance to our nation's rivers may affect historic structures and archaeological sites. This can trigger state and federal historic preservation laws, and interest in preserving a piece of local history, as well as providing an opportunity for historic discovery (McClain, et al., 2008). So, how do you determine the best method of restoring fish passage for your project? Congress passed the National Environmental Policy Act (NEPA), Public Law (P.L.) 91-190 in 1970 to establish a national policy for the protection and maintenance of the environment. The law provided a process all federal agencies must follow in evaluating the potential impacts a project has on the environment. Following the NEPA process leads to the publication of an Environmental Assessment which contains a compilation of available data regarding the project, including public comments, that allows decision makers to make educated and informed decisions. This paper addresses the National Environmental Policy Act (NEPA) and how it served as the decision document in determining the best alternative to restore fish passage at the Woodland Dam. Specifically, the paper will address environmental considerations typical of urban streams and the historical considerations associated with modifying a dam originally constructed in the 1640's. Emphasis will be placed on the interagency coordination between the U.S. Army Corps of Engineers (Corps), the Pennsylvania Department of Environmental Protection (PaDEP) and the Pennsylvania Historical & Museum Commission (PHMC). We will focus on how issues are resolved concerning environmental benefits and impacts balanced against maintaining our historical and cultural resources. JF - Watershed Management 2010: Innovations in Watershed Management under Land Use and Climate Change AU - Eberle, Mark AU - Minnichbach, Nicole AU - Rourke, Erik AD - U.S. Army Corps of Engineers, Philadelphia District, Wanamaker Building, 100 Penn Square East, Philadelphia, Pennsylvania 19107. Y1 - 2010///0, PY - 2010 DA - 0, 2010 SP - 388 EP - 396 KW - ASFA 1: Biological Sciences & Living Resources; ASFA Aquaculture Abstracts; Aqualine Abstracts; Water Resources Abstracts KW - Fish management KW - Restoration KW - Environmental issues KW - Rivers and streams KW - Fish Passages KW - Watershed Management KW - Freshwater KW - Streams KW - Environmental factors KW - Fishery policy KW - Dams KW - Environmental Policy KW - Rivers KW - Fishways KW - River discharge KW - Environmental Protection KW - Spawning KW - Channels KW - Habitat improvement KW - Legal aspects KW - USA, Pennsylvania KW - Migrations KW - Environmental conditions KW - SW 5040:Data acquisition KW - AQ 00008:Effects of Pollution KW - Q1 08121:Law, policy, economics and social sciences KW - Q3 08587:Diseases of Cultured Organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1014098213?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Watershed+Management+2010%3A+Innovations+in+Watershed+Management+under+Land+Use+and+Climate+Change&rft.atitle=Fish+Passage+Restoration+and+the+NEPA+Process%3A+Balancing+Environmental+Considerations+with+Historical+and+Cultural+Resources&rft.au=Eberle%2C+Mark%3BMinnichbach%2C+Nicole%3BRourke%2C+Erik&rft.aulast=Eberle&rft.aufirst=Mark&rft.date=2010-01-01&rft.volume=&rft.issue=&rft.spage=388&rft.isbn=9780784411438&rft.btitle=&rft.title=Watershed+Management+2010%3A+Innovations+in+Watershed+Management+under+Land+Use+and+Climate+Change&rft.issn=&rft_id=info:doi/10.1061%2F41148%28389%2935 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2012-05-01 N1 - Last updated - 2017-02-01 N1 - SubjectsTermNotLitGenreText - Fishery policy; Fishways; Habitat improvement; Legal aspects; Migrations; River discharge; Environmental conditions; Environmental factors; Streams; Channels; Rivers; Dams; Environmental Policy; Fish Passages; Environmental Protection; Watershed Management; Spawning; USA, Pennsylvania; Freshwater DO - http://dx.doi.org/10.1061/41148(389)35 ER - TY - JOUR T1 - Riverine chemical fluxes vs. long-term weathering, central Panama AN - 1011394465; 2012-044556 JF - Geochimica et Cosmochimica Acta AU - Lyons, W Berry AU - Goldsmith, S T AU - Deuerling, K M AU - Hannah, L M AU - Harmon, R S AU - Anonymous Y1 - 2010 PY - 2010 DA - 2010 SP - 1 PB - Elsevier, New York, NY VL - 74 IS - 12, Suppl. 1 SN - 0016-7037, 0016-7037 KW - solute transport KW - soils KW - Panama KW - hydrology KW - chemical weathering KW - soil profiles KW - erosion KW - surface water KW - sedimentation KW - rivers and streams KW - watersheds KW - water erosion KW - hydrochemistry KW - fluvial sedimentation KW - weathering KW - saprolite KW - transport KW - cations KW - weathering rates KW - central Panama KW - geochemistry KW - Central America KW - 02B:Hydrochemistry KW - 21:Hydrogeology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1011394465?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Geochimica+et+Cosmochimica+Acta&rft.atitle=Riverine+chemical+fluxes+vs.+long-term+weathering%2C+central+Panama&rft.au=Lyons%2C+W+Berry%3BGoldsmith%2C+S+T%3BDeuerling%2C+K+M%3BHannah%2C+L+M%3BHarmon%2C+R+S%3BAnonymous&rft.aulast=Lyons&rft.aufirst=W&rft.date=2010-01-01&rft.volume=74&rft.issue=12%2C+Suppl.+1&rft.spage=A648&rft.isbn=&rft.btitle=&rft.title=Geochimica+et+Cosmochimica+Acta&rft.issn=00167037&rft_id=info:doi/ L2 - http://goldschmidt.info/2010/abstracts/A-Z+Index.pdf http://www.sciencedirect.com/science/journal/00167037 LA - English DB - GeoRef N1 - Conference title - 20th annual V. M. Goldschmidt conference N1 - Copyright - GeoRef, Copyright 2014, American Geosciences Institute. N1 - Date revised - 2012-01-01 N1 - PubXState - NY N1 - Last updated - 2014-09-18 N1 - CODEN - GCACAK N1 - SubjectsTermNotLitGenreText - cations; Central America; central Panama; chemical weathering; erosion; fluvial sedimentation; geochemistry; hydrochemistry; hydrology; Panama; rivers and streams; saprolite; sedimentation; soil profiles; soils; solute transport; surface water; transport; water erosion; watersheds; weathering; weathering rates ER - TY - JOUR T1 - An evaluation of suspicious powder screening tools for first responders AN - 21093954; 11186682 AB - Field screening tools are required which would allow first responders to quickly ascertain if a suspicious powder poses a potential threat necessitating additional testing for biological pathogens such as Bacillus anthracis. In this study, three commercially available generic screening technologies were evaluated for the effectiveness to accurately differentiate between a hoax powder and a true biological threat. The BioCheck super(()R) Kit was able to detect the following biological agents 1x10 super(8)CFU of B. anthracis Sterne (washed 4 times), 1x10 super(7)CFU of B. anthracis Sterne (washed 2 times), 1x10 super(7)CFU of Yersinia pestis A1122, and 100kg of ricin. The Prime Alert(TM) kit was able to detect 2x10 super(1) super(0)CFU of B. anthracis Sterne 4x, 1x10 super(9)CFU of B. anthracis Sterne 2x, and 1x10 super(8)CFU of Y. pestis A1122. The Prime Alert(TM) kit was not able to detect ricin. The Profile super(()R)-1 kit was able to detect 1x10 super(4)CFU of B. anthracis Sterne 4x and B. anthracis Sterne 2x, and 1x10 super(6)CFU of Y. pestis A1122. The Profile super(()R)-1 kit was not able to detect ricin. All of the kits showed positive results for powders containing components specifically targeted by the particular technology being used. Each technology assessed in this evaluation employs a different mechanism for the detection of biological materials and it is important that first responders are aware of the strengths and the limitations of each system so that they can effectively employ the technology to protect the homeland. JF - Journal of Hazardous Materials AU - Poore, C AU - Clark, P AU - Emanuel, P A AD - 5183 Blackhawk Road, Aberdeen Proving Ground, MD 21010-5424, United States, Carrie.Poore@us.army.mil Y1 - 2009/12/30/ PY - 2009 DA - 2009 Dec 30 SP - 559 EP - 565 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 172 IS - 2-3 SN - 0304-3894, 0304-3894 KW - Toxicology Abstracts; Environment Abstracts KW - Powder KW - Ricin KW - Yersinia pestis KW - Pathogens KW - Bacillus anthracis KW - Technology KW - X 24370:Natural Toxins KW - ENA 07:General UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21093954?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Hazardous+Materials&rft.atitle=An+evaluation+of+suspicious+powder+screening+tools+for+first+responders&rft.au=Poore%2C+C%3BClark%2C+P%3BEmanuel%2C+P+A&rft.aulast=Poore&rft.aufirst=C&rft.date=2009-12-30&rft.volume=172&rft.issue=2-3&rft.spage=559&rft.isbn=&rft.btitle=&rft.title=Journal+of+Hazardous+Materials&rft.issn=03043894&rft_id=info:doi/10.1016%2Fj.jhazmat.2009.05.142 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-11-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Powder; Ricin; Pathogens; Technology; Yersinia pestis; Bacillus anthracis DO - http://dx.doi.org/10.1016/j.jhazmat.2009.05.142 ER - TY - CPAPER T1 - Force Health Protection: Preventive Medicine and Health Promotion Leadership T2 - 57th Annual Meeting of the Entomological Society of America AN - 42285770; 5629212 JF - 57th Annual Meeting of the Entomological Society of America AU - Blow, Jamie Y1 - 2009/12/13/ PY - 2009 DA - 2009 Dec 13 KW - Health promotion KW - Lead KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42285770?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=57th+Annual+Meeting+of+the+Entomological+Society+of+America&rft.atitle=Force+Health+Protection%3A+Preventive+Medicine+and+Health+Promotion+Leadership&rft.au=Blow%2C+Jamie&rft.aulast=Blow&rft.aufirst=Jamie&rft.date=2009-12-13&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=57th+Annual+Meeting+of+the+Entomological+Society+of+America&rft.issn=&rft_id=info:doi/ L2 - http://esa.confex.com/esa/2009/webprogram/start.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A Normalized Weighted Entropy Measure for Sensor Allocation Within Simulations T2 - 2009 Conference of the Winter Simulation Conference Foundation (WSC 2009) AN - 42143591; 5557103 JF - 2009 Conference of the Winter Simulation Conference Foundation (WSC 2009) AU - Ahner, Darryl Y1 - 2009/12/13/ PY - 2009 DA - 2009 Dec 13 KW - Simulation KW - Sensors KW - Entropy KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42143591?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Conference+of+the+Winter+Simulation+Conference+Foundation+%28WSC+2009%29&rft.atitle=A+Normalized+Weighted+Entropy+Measure+for+Sensor+Allocation+Within+Simulations&rft.au=Ahner%2C+Darryl&rft.aulast=Ahner&rft.aufirst=Darryl&rft.date=2009-12-13&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Conference+of+the+Winter+Simulation+Conference+Foundation+%28WSC+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.wintersim.org/prog09wsc.htm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Markov Models for Actin Polymer Dynamics T2 - American Society for Cell Biology 49th Annual Meeting AN - 42336391; 5646918 JF - American Society for Cell Biology 49th Annual Meeting AU - Szabo, Csilla Y1 - 2009/12/05/ PY - 2009 DA - 2009 Dec 05 KW - Polymers KW - Actin KW - Models KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42336391?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=American+Society+for+Cell+Biology+49th+Annual+Meeting&rft.atitle=Markov+Models+for+Actin+Polymer+Dynamics&rft.au=Szabo%2C+Csilla&rft.aulast=Szabo&rft.aufirst=Csilla&rft.date=2009-12-05&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=American+Society+for+Cell+Biology+49th+Annual+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.ascb.org/meetings/Docs/FINAL%20PROGRAM_lo%20res%20for%20web .pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Why are American Kestrel (Falco sparverius) Populations Declining in North America? Evidence from Nest-Box Programs AN - 907151735; 14135715 AB - Declines in American Kestrel (Falco sparverius) populations are widely reported, and Breeding Bird Survey (BBS) data suggest that the North American population declined significantly from 1984 to 2007. Potential causes include the spread of West Nile virus (WNV), increases in populations of Cooper's Hawks (Accipiter cooperii), and loss of suitable habitat. We examined trends in the numbers of both migratory and resident kestrel populations that use nest boxes in eight study areas in Florida, Georgia, Virginia and Maryland, New Jersey, Massachusetts, Pennsylvania, Saskatchewan, and the Yukon Territory, 1984-2007. All eight populations underwent significant declines; the mean annual decline in nest-box occupancy rate was 3.0% and ranged from 0.6% in Pennsylvania to 4.7% in New Jersey. Except for the most recent nest-box program, established in 1995 and declining since 2002, all nest-box populations began to experience declines before WNV arrived in North America in 1999. To test whether changes in kestrel population densities generally are associated with the opposite trend in Cooper's Hawks, we examined the 42 BBS physiographic regions for which trends for both species were available. No significant correlations were detected for the period 1966-2007, or for 1980-2007, more closely concurrent with our nest-box data. Christmas Bird Count data from 1959 through 1988 also failed to demonstrate a significant correlation. Finally, the habitat within our study areas still appears suitable, and the remaining kestrels appear healthy and have high reproductive success. Thus, the principal cause of the decline probably lies elsewhere, perhaps on the wintering grounds or along migration routes. Further, for both migratory and resident populations, the decline in nest-box occupancy may reflect regional declines, which would reduce the number of individuals available for replacing breeding birds that have died or dispersed. JF - Journal of Raptor Research AU - Smallwood, John A AU - Causey, Mark F AU - Mossop, David H AU - Klucsarits, James R AU - Robertson, Bob AU - Robertson, Sue AU - Mason, Joey AU - Maurer, Michael J AU - Melvin, Richard J AU - Dawson, Russell D AU - Bortolotti, Gary R AU - Parrish, John W AU - Breen, Timothy F AU - Boyd, Kenneth AD - U.S. Army Corps of Engineering, Clarks Hill, SC 29821 U.S.A Y1 - 2009/12// PY - 2009 DA - Dec 2009 SP - 274 EP - 282 PB - Raptor Research Foundation VL - 43 IS - 4 SN - 0892-1016, 0892-1016 KW - Ecology Abstracts KW - Data processing KW - Falco sparverius KW - Accipiter cooperii KW - Recruitment KW - Population density KW - Territory KW - Habitat KW - Migration KW - Breeding KW - Nest boxes KW - West Nile virus KW - Breeding success KW - D 04040:Ecosystem and Ecology Studies UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/907151735?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aecology&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Raptor+Research&rft.atitle=Why+are+American+Kestrel+%28Falco+sparverius%29+Populations+Declining+in+North+America%3F+Evidence+from+Nest-Box+Programs&rft.au=Smallwood%2C+John+A%3BCausey%2C+Mark+F%3BMossop%2C+David+H%3BKlucsarits%2C+James+R%3BRobertson%2C+Bob%3BRobertson%2C+Sue%3BMason%2C+Joey%3BMaurer%2C+Michael+J%3BMelvin%2C+Richard+J%3BDawson%2C+Russell+D%3BBortolotti%2C+Gary+R%3BParrish%2C+John+W%3BBreen%2C+Timothy+F%3BBoyd%2C+Kenneth&rft.aulast=Smallwood&rft.aufirst=John&rft.date=2009-12-01&rft.volume=43&rft.issue=4&rft.spage=274&rft.isbn=&rft.btitle=&rft.title=Journal+of+Raptor+Research&rft.issn=08921016&rft_id=info:doi/10.3356%2FJRR-08-83.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-11-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Data processing; Breeding; Recruitment; Population density; Territory; Nest boxes; Habitat; Migration; Breeding success; Falco sparverius; Accipiter cooperii; West Nile virus DO - http://dx.doi.org/10.3356/JRR-08-83.1 ER - TY - JOUR T1 - Botulinum neurotoxin vaccines: Past history and recent developments. AN - 754023874; 19684478 AB - Botulinum toxin may cause a neuroparalytic illness that may result in respiratory failure and require prolonged mechanical ventilation. As medical resources needed for supportive care of botulism in a bioterrorist event may quickly overwhelm the local healthcare systems, biodefense research efforts have been directed towards the development of a vaccine to prevent botulism. While human botulism has been caused only by toxin serotypes A, B, and E (rarely serotype F), all seven known immunologically distinct toxin serotypes (A - G) may potentially cause intoxication in humans from a bioterrorist event. A pentavalent (ABCDE) botulinum toxoid (PBT) has been administered as an investigation new drug (IND) to at-risk individuals for nearly 50 years. Due to declining immunogenicity of the PBT, research efforts have been directed at development of both improved (less local reactogenicity) botulinum toxoids and recombinant vaccines as potential vaccine candidates to replace the PBT. JF - Human vaccines AU - Rusnak, Janice M AU - Smith, Leonard A AD - Clinical Research Management, Inc., USA. Janice.Rusnak@amedd.army.mil Y1 - 2009/12// PY - 2009 DA - December 2009 SP - 794 EP - 805 VL - 5 IS - 12 KW - Bacterial Vaccines KW - 0 KW - Vaccines, Synthetic KW - Botulinum Toxins KW - EC 3.4.24.69 KW - Index Medicus KW - History KW - Humans KW - Vaccines, Synthetic -- immunology KW - Vaccines, Synthetic -- genetics KW - Bacterial Vaccines -- immunology KW - Botulinum Toxins -- immunology KW - Botulism -- prevention & control KW - Bacterial Vaccines -- genetics KW - Botulinum Toxins -- genetics KW - Botulism -- immunology KW - Bioterrorism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754023874?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Human+vaccines&rft.atitle=Botulinum+neurotoxin+vaccines%3A+Past+history+and+recent+developments.&rft.au=Rusnak%2C+Janice+M%3BSmith%2C+Leonard+A&rft.aulast=Rusnak&rft.aufirst=Janice&rft.date=2009-12-01&rft.volume=5&rft.issue=12&rft.spage=794&rft.isbn=&rft.btitle=&rft.title=Human+vaccines&rft.issn=1554-8619&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-12-08 N1 - Date created - 2010-09-08 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Effects of bandwidth on auditory localization with a noise masker. AN - 742783709; pmid-20000933 AB - Although high-frequency content is known to be critically important for the accurate location of isolated sounds, relatively little is known about the importance of high-frequency spectral content for the localization of sounds in the presence of a masker. In this experiment, listeners were asked to identify the location of a pulsed-noise target in the presence of a randomly located continuous noise masker. Both the target and masker were low-pass filtered at one of eight cutoff frequencies ranging from 1 to 16 kHz, and the signal-to-noise ratio was varied from -12 to +12 dB. The results confirm the importance of high frequencies for the localization of isolated sounds, and show that high-frequency content remains critical in cases where the target sound is masked by a spatially separated masker. In fact, when two sources of the same level are randomly located in space, these results show that a decrease in stimulus bandwidth from 16 to 12 kHz might result in a 30% increase in overall localization error. JF - The Journal of the Acoustical Society of America AU - Brungart, Douglas S AU - Simpson, Brian D AD - Air Force Research Laboratory, 2610 Seventh Street, WPAFB, Ohio 45433, USA. douglas.brungart@us.army.mil Y1 - 2009/12// PY - 2009 DA - Dec 2009 SP - 3199 EP - 3208 VL - 126 IS - 6 SN - 0001-4966, 0001-4966 KW - Index Medicus KW - National Library of Medicine KW - Young Adult KW - Analysis of Variance KW - Signal Detection, Psychological KW - Humans KW - Sound Spectrography KW - Task Performance and Analysis KW - Psychoacoustics KW - Acoustic Stimulation KW - Ear KW - Male KW - Female KW - Sound Localization KW - Noise KW - Perceptual Masking UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742783709?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+the+Acoustical+Society+of+America&rft.atitle=Effects+of+bandwidth+on+auditory+localization+with+a+noise+masker.&rft.au=Brungart%2C+Douglas+S%3BSimpson%2C+Brian+D&rft.aulast=Brungart&rft.aufirst=Douglas&rft.date=2009-12-01&rft.volume=126&rft.issue=6&rft.spage=3199&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+the+Acoustical+Society+of+America&rft.issn=00014966&rft_id=info:doi/ LA - English (eng) DB - ComDisDome N1 - Date revised - 2010-04-13 N1 - Last updated - 2010-09-25 ER - TY - JOUR T1 - Effects of 4-pyridine aldoxime on nerve agent-inhibited acetylcholinesterase activity in guinea pigs. AN - 733611803; 19763542 AB - Methoxime (MMB-4) is a leading candidate oxime acetylcholinesterase (AChE) reactivator to replace pralidoxime (2-PAM) for therapeutic treatment of nerve agent intoxication. 4-Pyridine aldoxime (4-PA) is a synthetic starting material, a breakdown product, and a probable metabolite of MMB-4. There is a possibility that 4-PA may adversely interact with the nerve agent, thereby affecting nerve agent toxicity and biological AChE activity. This study evaluated the effects of 4-PA on sarin (GB)-, cyclosarin (GF)-, and VX-induced toxicity and AChE activity in blood, brain, and peripheral tissues of guinea pigs. Animals were pretreated with atropine methyl nitrate (1.0 mg/kg, im) 15 min prior to subcutaneous administration with 1.0 x LD(50) of GB, GF, or VX and then treated 15 min after the administration of nerve agents with 4-PA (3.5, 7.0, or 14.0 mg/kg, im). The dose-response effects of 4-PA alone were also examined. Toxic signs and lethality were monitored, blood and tissues were collected, and AChE activities were determined at 60 min after nerve agent administration. Under the condition of this study, all animals exposed to nerve agents exhibited some degree of toxic signs such as salivation, lacrimation, rhinorrhea, and convulsions. 4-PA at the three doses tested neither induced toxic signs nor altered the toxicity of GB, GF, or VX at the 1.0 x LD(50) exposure dose. Additionally, it did not modify the AChE activity in blood, brain, and peripheral tissues by itself or affect the AChE activity inhibited by a 1.0 x LD(50) dose of these three nerve agents in guinea pigs. JF - Archives of toxicology AU - Shih, Tsung-Ming AU - Skovira, Jacob W AU - McDonough, John H AD - Pharmacology Branch, Research Division, US Army Medical Research Institute of Chemical Defense, ATTN: MCMR-CDR-P, 3100 Ricketts Point Road, Aberdeen Proving Ground, Aberdeen, MD 21010-5400, USA. tsungming.a.shih@us.army.mil Y1 - 2009/12// PY - 2009 DA - December 2009 SP - 1083 EP - 1089 VL - 83 IS - 12 KW - Chemical Warfare Agents KW - 0 KW - Cholinesterase Inhibitors KW - Cholinesterase Reactivators KW - Organophosphorus Compounds KW - Organothiophosphorus Compounds KW - Oximes KW - pyridine-4-aldoxime KW - 696-54-8 KW - VX KW - 9A4381183B KW - Sarin KW - B4XG72QGFM KW - Acetylcholinesterase KW - EC 3.1.1.7 KW - cyclohexyl methylphosphonofluoridate KW - VM36F9N236 KW - Index Medicus KW - Seizures -- chemically induced KW - Animals KW - Drug Interactions KW - Tears -- secretion KW - Guinea Pigs KW - Dose-Response Relationship, Drug KW - Salivation -- drug effects KW - Longevity -- drug effects KW - Organophosphorus Compounds -- toxicity KW - Sarin -- toxicity KW - Male KW - Organothiophosphorus Compounds -- toxicity KW - Oximes -- pharmacology KW - Cholinesterase Reactivators -- pharmacology KW - Cholinesterase Inhibitors -- toxicity KW - Acetylcholinesterase -- metabolism KW - Neurotoxicity Syndromes -- etiology KW - Neurotoxicity Syndromes -- enzymology KW - Chemical Warfare Agents -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733611803?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Archives+of+toxicology&rft.atitle=Effects+of+4-pyridine+aldoxime+on+nerve+agent-inhibited+acetylcholinesterase+activity+in+guinea+pigs.&rft.au=Shih%2C+Tsung-Ming%3BSkovira%2C+Jacob+W%3BMcDonough%2C+John+H&rft.aulast=Shih&rft.aufirst=Tsung-Ming&rft.date=2009-12-01&rft.volume=83&rft.issue=12&rft.spage=1083&rft.isbn=&rft.btitle=&rft.title=Archives+of+toxicology&rft.issn=1432-0738&rft_id=info:doi/10.1007%2Fs00204-009-0465-4 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2011-06-07 N1 - Date created - 2010-01-21 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1007/s00204-009-0465-4 ER - TY - JOUR T1 - Chinese energy policy in Central and South Asia AN - 60501731; 201006546 AB - China has exploited its relatively strong position following the current global financial and economic crisis, to buy up energy positions throughout Asia. In doing so it is using the tactics it had developed earlier when energy prices were quite high to buttress its energy security. That security entails having multiple secure sources of energy over land that cannot be interdicted by hostile naval forces. But beyond that, China's stronger position vis-a-vis distressed firms and governments allows it not only to buy key energy holdings, but also to exercise greater influence upon these firms' and states' policies and induce them to accommodate their policy preferences to Beijing's desiderata. The evidence brought forward here, concerning Russia, Kazakhstan, Myanmar, and Iran suggests that we are beginning to see a pattern of China leveraging its superior economic position in the current climate to induce this accommodating behavior and thereby begin to reorient security behavior in Asia even if it is all done by purely peaceful and economic means. Adapted from the source document. JF - The Korean Journal of Defense Analysis AU - Blank, Stephen AD - Studies Institute, U.S. Army War College, Pennsylvania, USA Y1 - 2009/12// PY - 2009 DA - December 2009 SP - 435 EP - 453 PB - Routledge/Taylor & Francis, UK VL - 21 IS - 4 SN - 1016-3271, 1016-3271 KW - Peoples Republic of China KW - Energy KW - Kazakhstan KW - Asia KW - Energy Policy KW - National Security KW - article KW - 9141: political economy; political economy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60501731?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awpsa&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Korean+Journal+of+Defense+Analysis&rft.atitle=Chinese+energy+policy+in+Central+and+South+Asia&rft.au=Blank%2C+Stephen&rft.aulast=Blank&rft.aufirst=Stephen&rft.date=2009-12-01&rft.volume=21&rft.issue=4&rft.spage=435&rft.isbn=&rft.btitle=&rft.title=The+Korean+Journal+of+Defense+Analysis&rft.issn=10163271&rft_id=info:doi/10.1080%2F10163270903298926 LA - English DB - Worldwide Political Science Abstracts N1 - Date revised - 2010-02-03 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Peoples Republic of China; National Security; Energy Policy; Energy; Asia; Kazakhstan DO - http://dx.doi.org/10.1080/10163270903298926 ER - TY - JOUR T1 - Investigating the fate of nitroaromatic (TNT) and nitramine (RDX and HMX) explosives in fractured and pristine soils AN - 50117682; 2010-006577 JF - Journal of Environmental Quality AU - Douglas, Thomas A AU - Walsh, Marianne E AU - McGrath, Christian J AU - Weiss, Charles A, Jr Y1 - 2009/12// PY - 2009 DA - December 2009 SP - 2285 EP - 2294 PB - American Society of Agronomy, [and] Crop Science Society of America, [and] Soil Science Society of America, Madison, WI VL - 38 IS - 6 SN - 0047-2425, 0047-2425 KW - soils KW - experimental studies KW - pollutants KW - pollution KW - trinitrotoluene KW - RDX KW - aqueous solutions KW - laboratory studies KW - triazines KW - sample preparation KW - organic compounds KW - mitigation KW - mineral composition KW - military geology KW - HMX KW - explosives KW - ecology KW - chemical composition KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50117682?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Environmental+Quality&rft.atitle=Investigating+the+fate+of+nitroaromatic+%28TNT%29+and+nitramine+%28RDX+and+HMX%29+explosives+in+fractured+and+pristine+soils&rft.au=Douglas%2C+Thomas+A%3BWalsh%2C+Marianne+E%3BMcGrath%2C+Christian+J%3BWeiss%2C+Charles+A%2C+Jr&rft.aulast=Douglas&rft.aufirst=Thomas&rft.date=2009-12-01&rft.volume=38&rft.issue=6&rft.spage=2285&rft.isbn=&rft.btitle=&rft.title=Journal+of+Environmental+Quality&rft.issn=00472425&rft_id=info:doi/10.2134%2Fjeq2008.0477 L2 - http://jeq.scijournals.org/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2010-01-01 N1 - Number of references - 47 N1 - PubXState - WI N1 - Document feature - illus. incl. 4 tables N1 - Last updated - 2012-06-07 N1 - CODEN - JEVQAA N1 - SubjectsTermNotLitGenreText - aqueous solutions; chemical composition; ecology; experimental studies; explosives; HMX; laboratory studies; military geology; mineral composition; mitigation; organic compounds; pollutants; pollution; RDX; sample preparation; soils; triazines; trinitrotoluene DO - http://dx.doi.org/10.2134/jeq2008.0477 ER - TY - JOUR T1 - Quantifying periglacial erosion; insights on a glacial sediment budget, Matanuska Glacier, Alaska AN - 50103064; 2010-014148 JF - Earth Surface Processes and Landforms AU - O'Farrell, Colin R AU - Heimsath, Arjun M AU - Lawson, Daniel E AU - Jorgensen, Laura M AU - Evenson, Edward B AU - Larson, Grahame J AU - Denner, Jon Y1 - 2009/12// PY - 2009 DA - December 2009 SP - 2008 EP - 2022 PB - Wiley, Chichester VL - 34 IS - 15 SN - 0197-9337, 0197-9337 KW - United States KW - isotopes KW - erosion KW - cosmogenic elements KW - periglacial features KW - erosion rates KW - erosion features KW - modern KW - Matanuska Glacier KW - glacial erosion KW - radioactive isotopes KW - quantitative analysis KW - sediment yield KW - absolute age KW - alkaline earth metals KW - Be-10 KW - landform evolution KW - sedimentation KW - cosmochronology KW - glaciers KW - Southern Alaska KW - metals KW - glacial sedimentation KW - Alaska KW - glacial geology KW - geomorphology KW - Chugach Mountains KW - beryllium KW - 23:Geomorphology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50103064?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Earth+Surface+Processes+and+Landforms&rft.atitle=Quantifying+periglacial+erosion%3B+insights+on+a+glacial+sediment+budget%2C+Matanuska+Glacier%2C+Alaska&rft.au=O%27Farrell%2C+Colin+R%3BHeimsath%2C+Arjun+M%3BLawson%2C+Daniel+E%3BJorgensen%2C+Laura+M%3BEvenson%2C+Edward+B%3BLarson%2C+Grahame+J%3BDenner%2C+Jon&rft.aulast=O%27Farrell&rft.aufirst=Colin&rft.date=2009-12-01&rft.volume=34&rft.issue=15&rft.spage=2008&rft.isbn=&rft.btitle=&rft.title=Earth+Surface+Processes+and+Landforms&rft.issn=01979337&rft_id=info:doi/10.1002%2Fesp.1885 L2 - http://www3.interscience.wiley.com/journal/117935722/grouphome/home.html LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2010-01-01 N1 - Number of references - 64 N1 - Document feature - illus. incl. 4 tables, sketch maps N1 - SuppNotes - NSF grants EAR-9909335 and EAR-0239655 N1 - Last updated - 2012-06-07 N1 - CODEN - ESPRDT N1 - SubjectsTermNotLitGenreText - absolute age; Alaska; alkaline earth metals; Be-10; beryllium; Chugach Mountains; cosmochronology; cosmogenic elements; erosion; erosion features; erosion rates; geomorphology; glacial erosion; glacial geology; glacial sedimentation; glaciers; isotopes; landform evolution; Matanuska Glacier; metals; modern; periglacial features; quantitative analysis; radioactive isotopes; sediment yield; sedimentation; Southern Alaska; United States DO - http://dx.doi.org/10.1002/esp.1885 ER - TY - JOUR T1 - Clinical and Molecular Evidence for a Case of Buruli Ulcer (Mycobacterium ulcerans Infection) in Kenya AN - 21275345; 11848076 AB - Mycobacterium ulcerans infection is an emerging disease that causes indolent, necrotizing skin lesions known as Buruli ulcer (BU) and occasional contiguous or metastatic bone lesions. Buruli ulcer is named after Buruli County in Uganda (east Africa), where an epidemic occurred in the 1960s. Today, BU is most common in central and west Africa. We describe clinical and molecular evidence for a case of BU in Kenya. JF - American Journal of Tropical Medicine and Hygiene AU - Walsh, D S AU - Eyase, F AU - Onyango, D AU - Odindo, A AU - Otieno, W AU - Waitumbi, J N AU - Bulimo, W D AU - Schnabel, D C AU - Meyers, WM AU - Portaels, F AD - Walter Reed Project, United States Army Medical Research Unit-Kenya, PO Box 54, Kisumu 10400, Kenya, doudas.s.walsh@us.army.mil Y1 - 2009/12// PY - 2009 DA - December 2009 SP - 1110 EP - 1113 VL - 81 IS - 6 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology KW - Bone KW - Metastases KW - Mycobacterium ulcerans KW - Epidemics KW - Skin diseases KW - Infection KW - Buruli ulcer KW - K 03400:Human Diseases KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21275345?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Clinical+and+Molecular+Evidence+for+a+Case+of+Buruli+Ulcer+%28Mycobacterium+ulcerans+Infection%29+in+Kenya&rft.au=Walsh%2C+D+S%3BEyase%2C+F%3BOnyango%2C+D%3BOdindo%2C+A%3BOtieno%2C+W%3BWaitumbi%2C+J+N%3BBulimo%2C+W+D%3BSchnabel%2C+D+C%3BMeyers%2C+WM%3BPortaels%2C+F&rft.aulast=Walsh&rft.aufirst=D&rft.date=2009-12-01&rft.volume=81&rft.issue=6&rft.spage=1110&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - Last updated - 2016-05-13 N1 - SubjectsTermNotLitGenreText - Metastases; Bone; Epidemics; Skin diseases; Infection; Buruli ulcer; Mycobacterium ulcerans ER - TY - JOUR T1 - Water-Borne Outbreak of Oropharyngeal and Glandular Tularemia in Georgia: Investigation and Follow-up AN - 21258253; 11833231 AB - Background: : In November 2006, an outbreak of waterborne tularemia occurred in an eastern region in the Republic of Georgia. Outbreak investigation revealed 26 cases: 21 oropharyngeal and 5 glandular tularemia cases. Methods: : The presentation of the index case triggered an outbreak investigation involving the collection of clinical/ epidemiological data, application of tularine skin test, and laboratory confirmation of the possible cases using the tube agglutination test and polymerase chain reaction (PCR) testing. Serology results were verified by enzyme-linked immunosorbent assay (ELISA) and Western blot. A case- control study along with follow-up was conducted 4 months after the index case presentation. Results: : Exudative pharyngitis, predominantly laterocervical adenitis, fever, and headache were the most prevalent clinical signs/symptoms observed. Depressed mood, concentration difficulties, and sleep disturbance were also detected. Bubo aspirates tested by PCR were positive in 4/4 cases and pharyngeal swabs also tested by PCR were positive in 2/3 cases. Francisella tularensis was isolated from the water samples. Comparison of the cases and controls did not reveal any statistically significant risk factors. A follow-up investigation revealed cases with protracted symptoms of fatigue, headache, and sleep disturbance. Additionally, 8/26 cases still had cervical adenopathy of prominent size. A delay in diagnosis was associated with persistent lymphadenopathy on follow-up examination (p = 0.05). Conclusion: : We observed unique features of persistent neuropsychiatric symptoms and lymphadenopathy 5 months after tularemia infection which were associated with delayed diagnosis and the lack of prompt response to therapy. This outbreak of oropharyngeal tularemia emphasizes the importance of a rapid diagnostic and investigative response to tularemia. This type of response can prevent ongoing exposure, as well as provide expeditious treatment to mitigate persistent symptoms. JF - Infection AU - Chitadze, N AU - Kuchuloria, T AU - Clark, D V AU - Tsertsvadze, E AU - Chokheli, M AU - Tsertsvadze, N AU - Trapaidze, N AU - Lane, A AU - Bakanidze, L AU - Tsanava, S AU - Hepburn, MJ AU - Imnadze, P AD - National Center for Disease Control and Public Health, Tbilisi, Georgia, danielle.clarks3@us.army.mil danielle.clarks3@us.army.mil danielle.clarks3@us.army.mil danielle.clarks3@us.army.mil Y1 - 2009/12// PY - 2009 DA - Dec 2009 SP - 514 EP - 521 PB - Springer-Verlag (Heidelberg), Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 37 IS - 6 SN - 0300-8126, 0300-8126 KW - Microbiology Abstracts B: Bacteriology KW - Western blotting KW - Enzyme-linked immunosorbent assay KW - Fatigue KW - Pharynx KW - Data processing KW - Statistical analysis KW - Bubo KW - Francisella tularensis KW - Pharyngitis KW - Infection KW - Serology KW - Skin tests KW - Mood KW - Fever KW - Agglutination KW - Lymphadenopathy KW - Tularemia KW - Sleep KW - Risk factors KW - Headache KW - Polymerase chain reaction KW - Adenitis KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21258253?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Infection&rft.atitle=Water-Borne+Outbreak+of+Oropharyngeal+and+Glandular+Tularemia+in+Georgia%3A+Investigation+and+Follow-up&rft.au=Chitadze%2C+N%3BKuchuloria%2C+T%3BClark%2C+D+V%3BTsertsvadze%2C+E%3BChokheli%2C+M%3BTsertsvadze%2C+N%3BTrapaidze%2C+N%3BLane%2C+A%3BBakanidze%2C+L%3BTsanava%2C+S%3BHepburn%2C+MJ%3BImnadze%2C+P&rft.aulast=Chitadze&rft.aufirst=N&rft.date=2009-12-01&rft.volume=37&rft.issue=6&rft.spage=514&rft.isbn=&rft.btitle=&rft.title=2008+Annual+Meeting+and+Food+Expo+of+the+Institute+of+Food+Technologists&rft.issn=&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Western blotting; Enzyme-linked immunosorbent assay; Data processing; Pharynx; Fatigue; Statistical analysis; Pharyngitis; Infection; Serology; Skin tests; Fever; Mood; Tularemia; Lymphadenopathy; Agglutination; Risk factors; Sleep; Headache; Polymerase chain reaction; Adenitis; Bubo; Francisella tularensis DO - http://dx.doi.org/10.1007/s15010-009-8193-5 ER - TY - JOUR T1 - Characterization of an Antibody Depletion Assay for Analysis of Bactericidal Antibody Specificity AN - 21229398; 11811759 AB - Serum bactericidal antibodies are important for protection against systemic Neisseria meningitidis infections. Consequently, identifying the specific targets of bactericidal antibodies is important for understanding protective immunity to meningococcal disease and for vaccine development and evaluation. We have developed a new assay that can be used to investigate the specificity of serum bactericidal antibodies. Prior to testing for bactericidal activity, antibodies specific for a given antigen or group of antigens are depleted from a serum sample by incubation with the antigen(s) bound to the wells of a 96-well microplate. A dilution series of the antigen is bound to the plate to assess the effectiveness of the antigen in removing the bactericidal antibodies. Removal of antibodies with solid-phase antigen prior to bactericidal testing avoids depletion of complement by soluble immune complexes that can form when soluble antigen is present in the bactericidal test mixture (direct inhibition). The parameters associated with this assay are investigated and compared with those associated with a direct-inhibition assay. The bactericidal depletion assay can be an effective tool for studying the specificity of serum bactericidal antibodies. JF - Clinical and Vaccine Immunology AU - Zollinger, Wendell D AU - Moran, Elizabeth E AU - Schmiel, Deborah H AD - Walter Reed Army Institute of Research, 503 Robert Grant Ave., Silver Spring, Maryland 20910-7500, wendell.zollinger@us.army.mil Y1 - 2009/12// PY - 2009 DA - Dec 2009 SP - 1789 EP - 1795 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 16 IS - 12 SN - 1556-679X, 1556-679X KW - Microbiology Abstracts B: Bacteriology; Immunology Abstracts KW - Antibodies KW - Antigen-antibody complexes KW - Bactericidal activity KW - Immunity KW - Infection KW - Vaccines KW - meningococcal disease KW - Bacteria KW - Neisseria meningitidis KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21229398?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clinical+and+Vaccine+Immunology&rft.atitle=Characterization+of+an+Antibody+Depletion+Assay+for+Analysis+of+Bactericidal+Antibody+Specificity&rft.au=Zollinger%2C+Wendell+D%3BMoran%2C+Elizabeth+E%3BSchmiel%2C+Deborah+H&rft.aulast=Zollinger&rft.aufirst=Wendell&rft.date=2009-12-01&rft.volume=16&rft.issue=12&rft.spage=1789&rft.isbn=&rft.btitle=&rft.title=Clinical+and+Vaccine+Immunology&rft.issn=1556679X&rft_id=info:doi/10.1128%2FCVI.00255-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-01-01 N1 - Last updated - 2013-05-06 N1 - SubjectsTermNotLitGenreText - Antibodies; meningococcal disease; Antigen-antibody complexes; Immunity; Vaccines; Infection; Bactericidal activity; Bacteria; Neisseria meningitidis DO - http://dx.doi.org/10.1128/CVI.00255-09 ER - TY - JOUR T1 - Factor Structure and Measurement Invariance of a 10-ItemDecisional Balance Scale: Longitudinal and Subgroup Examination Within an Adult Diabetic Sample AN - 21109366; 11329126 AB - This study explores the longitudinal and subgroup measurement properties of a 10-item, physical activity decisional balance scale, previously published by Plotnikoff, Blanchard, Hotz, and Rhodes (2001), within a diabetic sample of Canadian adults. Results indicated that a three-factor measurement model consistently improved model fit compared to the previously published two-factor model. Evidence of configural, metric, and scalar measurement invariance across time and among subgroups suggests that the 10-item decisional balance scale is appropriate for investigating associative relationships with other constructs and for comparing group means of the pros and cons subscales among a variety of diabetic population subgroups. JF - Measurement in Physical Education and Exercise Science AU - Pickering, MA AU - Plotnikoff, R C AD - Army Center for Enhanced Performance, United States Military Academy, West Point, NY 10996, USA, michael.pickering@usma.edu Y1 - 2009/12// PY - 2009 DA - Dec 2009 SP - 206 EP - 226 VL - 13 IS - 4 SN - 1091-367X, 1091-367X KW - Physical Education Index KW - Evaluation KW - Measurement KW - Sport science KW - Adults KW - Exercise KW - Balance KW - Physical education KW - PE 090:Sports Medicine & Exercise Sport Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21109366?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Measurement+in+Physical+Education+and+Exercise+Science&rft.atitle=Factor+Structure+and+Measurement+Invariance+of+a+10-ItemDecisional+Balance+Scale%3A+Longitudinal+and+Subgroup+Examination+Within+an+Adult+Diabetic+Sample&rft.au=Pickering%2C+MA%3BPlotnikoff%2C+R+C&rft.aulast=Pickering&rft.aufirst=MA&rft.date=2009-12-01&rft.volume=13&rft.issue=4&rft.spage=206&rft.isbn=&rft.btitle=&rft.title=Measurement+in+Physical+Education+and+Exercise+Science&rft.issn=1091367X&rft_id=info:doi/10.1080%2F10913670903260086 LA - English DB - Physical Education Index N1 - Date revised - 2009-12-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Evaluation; Measurement; Sport science; Exercise; Adults; Balance; Physical education DO - http://dx.doi.org/10.1080/10913670903260086 ER - TY - CPAPER T1 - Implementing Information Assurance - Beyond Process T2 - 2009 Interservice/Industry Training, Simulation and Education Conference (I/ITSEC 2009) AN - 42287966; 5625714 JF - 2009 Interservice/Industry Training, Simulation and Education Conference (I/ITSEC 2009) AU - Piatek, Misty AU - Hamilton, Booz AU - Newkirk, James Y1 - 2009/11/30/ PY - 2009 DA - 2009 Nov 30 KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42287966?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Interservice%2FIndustry+Training%2C+Simulation+and+Education+Conference+%28I%2FITSEC+2009%29&rft.atitle=Implementing+Information+Assurance+-+Beyond+Process&rft.au=Piatek%2C+Misty%3BHamilton%2C+Booz%3BNewkirk%2C+James&rft.aulast=Piatek&rft.aufirst=Misty&rft.date=2009-11-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Interservice%2FIndustry+Training%2C+Simulation+and+Education+Conference+%28I%2FITSEC+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.iitsec.org/documents/2009ProgGuide_002.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Task Specific Simulations for Medical Training: Fidelity Requirements Compared with Levels of Care T2 - 2009 Interservice/Industry Training, Simulation and Education Conference (I/ITSEC 2009) AN - 42286388; 5625742 JF - 2009 Interservice/Industry Training, Simulation and Education Conference (I/ITSEC 2009) AU - Pettitt, Beth AU - Norfleet, Jack AU - Descheneaux, C Y1 - 2009/11/30/ PY - 2009 DA - 2009 Nov 30 KW - Training KW - Simulation KW - Fidelity KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42286388?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Interservice%2FIndustry+Training%2C+Simulation+and+Education+Conference+%28I%2FITSEC+2009%29&rft.atitle=Task+Specific+Simulations+for+Medical+Training%3A+Fidelity+Requirements+Compared+with+Levels+of+Care&rft.au=Pettitt%2C+Beth%3BNorfleet%2C+Jack%3BDescheneaux%2C+C&rft.aulast=Pettitt&rft.aufirst=Beth&rft.date=2009-11-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Interservice%2FIndustry+Training%2C+Simulation+and+Education+Conference+%28I%2FITSEC+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.iitsec.org/documents/2009ProgGuide_002.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Fielding Simulation and Training Systems Legally Without Accreditation T2 - 2009 Interservice/Industry Training, Simulation and Education Conference (I/ITSEC 2009) AN - 42283754; 5625716 JF - 2009 Interservice/Industry Training, Simulation and Education Conference (I/ITSEC 2009) AU - Thornley, Craig AU - Newkirk, James Y1 - 2009/11/30/ PY - 2009 DA - 2009 Nov 30 KW - Training KW - Simulation KW - Accreditation KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42283754?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Interservice%2FIndustry+Training%2C+Simulation+and+Education+Conference+%28I%2FITSEC+2009%29&rft.atitle=Fielding+Simulation+and+Training+Systems+Legally+Without+Accreditation&rft.au=Thornley%2C+Craig%3BNewkirk%2C+James&rft.aulast=Thornley&rft.aufirst=Craig&rft.date=2009-11-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Interservice%2FIndustry+Training%2C+Simulation+and+Education+Conference+%28I%2FITSEC+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.iitsec.org/documents/2009ProgGuide_002.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Positively Gaming the System: A VBS2(TM) Training Case Study T2 - 2009 Interservice/Industry Training, Simulation and Education Conference (I/ITSEC 2009) AN - 42283533; 5625626 JF - 2009 Interservice/Industry Training, Simulation and Education Conference (I/ITSEC 2009) AU - Atherton, Eric AU - Baxter, Holly Y1 - 2009/11/30/ PY - 2009 DA - 2009 Nov 30 KW - Case studies KW - Training KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42283533?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Interservice%2FIndustry+Training%2C+Simulation+and+Education+Conference+%28I%2FITSEC+2009%29&rft.atitle=Positively+Gaming+the+System%3A+A+VBS2%28TM%29+Training+Case+Study&rft.au=Atherton%2C+Eric%3BBaxter%2C+Holly&rft.aulast=Atherton&rft.aufirst=Eric&rft.date=2009-11-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Interservice%2FIndustry+Training%2C+Simulation+and+Education+Conference+%28I%2FITSEC+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.iitsec.org/documents/2009ProgGuide_002.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Decision Making with Digital Systems T2 - 2009 Interservice/Industry Training, Simulation and Education Conference (I/ITSEC 2009) AN - 42283063; 5625690 JF - 2009 Interservice/Industry Training, Simulation and Education Conference (I/ITSEC 2009) AU - Goodwin, Gregory Y1 - 2009/11/30/ PY - 2009 DA - 2009 Nov 30 KW - Decision making KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42283063?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Interservice%2FIndustry+Training%2C+Simulation+and+Education+Conference+%28I%2FITSEC+2009%29&rft.atitle=Decision+Making+with+Digital+Systems&rft.au=Goodwin%2C+Gregory&rft.aulast=Goodwin&rft.aufirst=Gregory&rft.date=2009-11-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Interservice%2FIndustry+Training%2C+Simulation+and+Education+Conference+%28I%2FITSEC+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.iitsec.org/documents/2009ProgGuide_002.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Rapid Training Development Tools for Operational Units T2 - 2009 Interservice/Industry Training, Simulation and Education Conference (I/ITSEC 2009) AN - 42281162; 5625646 JF - 2009 Interservice/Industry Training, Simulation and Education Conference (I/ITSEC 2009) AU - Shadrick, Scott AU - Palla, Amanda AU - Cianciolo, Anna Y1 - 2009/11/30/ PY - 2009 DA - 2009 Nov 30 KW - Training KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42281162?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Interservice%2FIndustry+Training%2C+Simulation+and+Education+Conference+%28I%2FITSEC+2009%29&rft.atitle=Rapid+Training+Development+Tools+for+Operational+Units&rft.au=Shadrick%2C+Scott%3BPalla%2C+Amanda%3BCianciolo%2C+Anna&rft.aulast=Shadrick&rft.aufirst=Scott&rft.date=2009-11-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Interservice%2FIndustry+Training%2C+Simulation+and+Education+Conference+%28I%2FITSEC+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.iitsec.org/documents/2009ProgGuide_002.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A History of Serious Games T2 - 2009 Interservice/Industry Training, Simulation and Education Conference (I/ITSEC 2009) AN - 42279727; 5625607 JF - 2009 Interservice/Industry Training, Simulation and Education Conference (I/ITSEC 2009) AU - Smith, Roger Y1 - 2009/11/30/ PY - 2009 DA - 2009 Nov 30 KW - Historical account KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42279727?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Interservice%2FIndustry+Training%2C+Simulation+and+Education+Conference+%28I%2FITSEC+2009%29&rft.atitle=A+History+of+Serious+Games&rft.au=Smith%2C+Roger&rft.aulast=Smith&rft.aufirst=Roger&rft.date=2009-11-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Interservice%2FIndustry+Training%2C+Simulation+and+Education+Conference+%28I%2FITSEC+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.iitsec.org/documents/2009ProgGuide_002.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Issues in Deployment of Serious Games T2 - 2009 Interservice/Industry Training, Simulation and Education Conference (I/ITSEC 2009) AN - 42279040; 5625702 JF - 2009 Interservice/Industry Training, Simulation and Education Conference (I/ITSEC 2009) AU - Durlach, Paula Y1 - 2009/11/30/ PY - 2009 DA - 2009 Nov 30 KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42279040?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Interservice%2FIndustry+Training%2C+Simulation+and+Education+Conference+%28I%2FITSEC+2009%29&rft.atitle=Issues+in+Deployment+of+Serious+Games&rft.au=Durlach%2C+Paula&rft.aulast=Durlach&rft.aufirst=Paula&rft.date=2009-11-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Interservice%2FIndustry+Training%2C+Simulation+and+Education+Conference+%28I%2FITSEC+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.iitsec.org/documents/2009ProgGuide_002.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Improving Company Commander's Visualization in Irregular Warfare T2 - 2009 Interservice/Industry Training, Simulation and Education Conference (I/ITSEC 2009) AN - 42278368; 5625644 JF - 2009 Interservice/Industry Training, Simulation and Education Conference (I/ITSEC 2009) AU - Lickteig, Carl AU - Stroupe, Heather AU - Cianciolo, Anna AU - Silverman, Mike AU - Menaker, Ellen Y1 - 2009/11/30/ PY - 2009 DA - 2009 Nov 30 KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42278368?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Interservice%2FIndustry+Training%2C+Simulation+and+Education+Conference+%28I%2FITSEC+2009%29&rft.atitle=Improving+Company+Commander%27s+Visualization+in+Irregular+Warfare&rft.au=Lickteig%2C+Carl%3BStroupe%2C+Heather%3BCianciolo%2C+Anna%3BSilverman%2C+Mike%3BMenaker%2C+Ellen&rft.aulast=Lickteig&rft.aufirst=Carl&rft.date=2009-11-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Interservice%2FIndustry+Training%2C+Simulation+and+Education+Conference+%28I%2FITSEC+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.iitsec.org/documents/2009ProgGuide_002.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Exploring the Use of a Massive Multiplayer Game (Mmpg) to Train Infantry Company Commanders T2 - 2009 Interservice/Industry Training, Simulation and Education Conference (I/ITSEC 2009) AN - 42274926; 5625659 JF - 2009 Interservice/Industry Training, Simulation and Education Conference (I/ITSEC 2009) AU - Beal, Scott Y1 - 2009/11/30/ PY - 2009 DA - 2009 Nov 30 KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42274926?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Interservice%2FIndustry+Training%2C+Simulation+and+Education+Conference+%28I%2FITSEC+2009%29&rft.atitle=Exploring+the+Use+of+a+Massive+Multiplayer+Game+%28Mmpg%29+to+Train+Infantry+Company+Commanders&rft.au=Beal%2C+Scott&rft.aulast=Beal&rft.aufirst=Scott&rft.date=2009-11-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Interservice%2FIndustry+Training%2C+Simulation+and+Education+Conference+%28I%2FITSEC+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.iitsec.org/documents/2009ProgGuide_002.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - NATO's Culminating Point T2 - 2009 Annual Meeting of the Northeastern Political Science Association AN - 42176040; 5569374 JF - 2009 Annual Meeting of the Northeastern Political Science Association AU - Hillison, Joel Y1 - 2009/11/19/ PY - 2009 DA - 2009 Nov 19 KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42176040?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Annual+Meeting+of+the+Northeastern+Political+Science+Association&rft.atitle=NATO%27s+Culminating+Point&rft.au=Hillison%2C+Joel&rft.aulast=Hillison&rft.aufirst=Joel&rft.date=2009-11-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Annual+Meeting+of+the+Northeastern+Political+Science+Association&rft.issn=&rft_id=info:doi/10.1016%2Fj.vaccine.2008.04.041 L2 - http://convention2.allacademic.com/one/npsa/npsa09/index.php?click_key =2&cmd=Multi+Search+View+Program+Load+Scheduled+Times&schedule_day=2 009-11-19+00%3A00%3A00&PHPSESSID=590cd226cdcaeb61b21aaefc6f7962db LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Viral Hemorrhagic Fevers in the Health Care Setting T2 - 58th Annual Meeting of the American Society of Tropical Medicine and Hygiene AN - 42233967; 5591383 JF - 58th Annual Meeting of the American Society of Tropical Medicine and Hygiene AU - Kortepeter, Mark Y1 - 2009/11/18/ PY - 2009 DA - 2009 Nov 18 KW - Health care KW - Hemorrhagic fever KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42233967?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=58th+Annual+Meeting+of+the+American+Society+of+Tropical+Medicine+and+Hygiene&rft.atitle=Viral+Hemorrhagic+Fevers+in+the+Health+Care+Setting&rft.au=Kortepeter%2C+Mark&rft.aulast=Kortepeter&rft.aufirst=Mark&rft.date=2009-11-18&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=58th+Annual+Meeting+of+the+American+Society+of+Tropical+Medicine+and+Hygiene&rft.issn=&rft_id=info:doi/ L2 - http://www.astmh.org/AM/Template.cfm?Section=Meeting_Archives&Template =/CM/ContentDisplay.cfm&ContentID=2309 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Development of a Broad Spectrum Flavivirus Quantitative Detection Assay Using Rt-Pcr/Electrospray Ionization Mass Spectrometry on the Ibis t5000 Platform T2 - 58th Annual Meeting of the American Society of Tropical Medicine and Hygiene AN - 42226744; 5592148 JF - 58th Annual Meeting of the American Society of Tropical Medicine and Hygiene AU - Grant, Rebecca AU - Baldwin, Carson AU - Turell, Michael AU - Rossi, Cindy AU - Feng, Li AU - Lovari, Robert AU - Blyn, Larry AU - Sampath, Ranga AU - Whitehouse, Chris Y1 - 2009/11/18/ PY - 2009 DA - 2009 Nov 18 KW - Mass spectroscopy KW - Polymerase chain reaction KW - Flavivirus KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42226744?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=58th+Annual+Meeting+of+the+American+Society+of+Tropical+Medicine+and+Hygiene&rft.atitle=Development+of+a+Broad+Spectrum+Flavivirus+Quantitative+Detection+Assay+Using+Rt-Pcr%2FElectrospray+Ionization+Mass+Spectrometry+on+the+Ibis+t5000+Platform&rft.au=Grant%2C+Rebecca%3BBaldwin%2C+Carson%3BTurell%2C+Michael%3BRossi%2C+Cindy%3BFeng%2C+Li%3BLovari%2C+Robert%3BBlyn%2C+Larry%3BSampath%2C+Ranga%3BWhitehouse%2C+Chris&rft.aulast=Grant&rft.aufirst=Rebecca&rft.date=2009-11-18&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=58th+Annual+Meeting+of+the+American+Society+of+Tropical+Medicine+and+Hygiene&rft.issn=&rft_id=info:doi/ L2 - http://www.astmh.org/AM/Template.cfm?Section=Meeting_Archives&Template =/CM/ContentDisplay.cfm&ContentID=2309 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Japanese Encephalitis in the Philippines: Chart Review and Laboratory Confirmed Hospitalized Cases T2 - 58th Annual Meeting of the American Society of Tropical Medicine and Hygiene AN - 42225869; 5592147 JF - 58th Annual Meeting of the American Society of Tropical Medicine and Hygiene AU - Alera, Maria Y1 - 2009/11/18/ PY - 2009 DA - 2009 Nov 18 KW - Philippines KW - Reviews KW - Hospitals KW - Encephalitis KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42225869?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=58th+Annual+Meeting+of+the+American+Society+of+Tropical+Medicine+and+Hygiene&rft.atitle=Japanese+Encephalitis+in+the+Philippines%3A+Chart+Review+and+Laboratory+Confirmed+Hospitalized+Cases&rft.au=Alera%2C+Maria&rft.aulast=Alera&rft.aufirst=Maria&rft.date=2009-11-18&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=58th+Annual+Meeting+of+the+American+Society+of+Tropical+Medicine+and+Hygiene&rft.issn=&rft_id=info:doi/ L2 - http://www.astmh.org/AM/Template.cfm?Section=Meeting_Archives&Template =/CM/ContentDisplay.cfm&ContentID=2309 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Dengue Surveillance in a Tertiary Hospital in Cebu City, Philippines T2 - 58th Annual Meeting of the American Society of Tropical Medicine and Hygiene AN - 42224801; 5592136 JF - 58th Annual Meeting of the American Society of Tropical Medicine and Hygiene AU - Alera, Maria Y1 - 2009/11/18/ PY - 2009 DA - 2009 Nov 18 KW - Philippines KW - Urban areas KW - Hospitals KW - Dengue KW - Cebus KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42224801?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=58th+Annual+Meeting+of+the+American+Society+of+Tropical+Medicine+and+Hygiene&rft.atitle=Dengue+Surveillance+in+a+Tertiary+Hospital+in+Cebu+City%2C+Philippines&rft.au=Alera%2C+Maria&rft.aulast=Alera&rft.aufirst=Maria&rft.date=2009-11-18&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=58th+Annual+Meeting+of+the+American+Society+of+Tropical+Medicine+and+Hygiene&rft.issn=&rft_id=info:doi/ L2 - http://www.astmh.org/AM/Template.cfm?Section=Meeting_Archives&Template =/CM/ContentDisplay.cfm&ContentID=2309 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Evaluation of Kenyan Mosquito Species as Vectors of West Nile Virus T2 - 58th Annual Meeting of the American Society of Tropical Medicine and Hygiene AN - 42224243; 5591590 JF - 58th Annual Meeting of the American Society of Tropical Medicine and Hygiene AU - Koka, Hellen AU - Turell, Micheal AU - Lutomiah, Joel AU - Makio, Albina AU - Muthoni, Milka AU - Mutisya, James AU - Yalwala, Santos AU - Limbaso, Samson AU - Schnabel, David AU - Sang, Rosemary Y1 - 2009/11/18/ PY - 2009 DA - 2009 Nov 18 KW - Vectors KW - Disease transmission KW - Public health KW - Aquatic insects KW - Hosts KW - West Nile virus KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42224243?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=58th+Annual+Meeting+of+the+American+Society+of+Tropical+Medicine+and+Hygiene&rft.atitle=Evaluation+of+Kenyan+Mosquito+Species+as+Vectors+of+West+Nile+Virus&rft.au=Koka%2C+Hellen%3BTurell%2C+Micheal%3BLutomiah%2C+Joel%3BMakio%2C+Albina%3BMuthoni%2C+Milka%3BMutisya%2C+James%3BYalwala%2C+Santos%3BLimbaso%2C+Samson%3BSchnabel%2C+David%3BSang%2C+Rosemary&rft.aulast=Koka&rft.aufirst=Hellen&rft.date=2009-11-18&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=58th+Annual+Meeting+of+the+American+Society+of+Tropical+Medicine+and+Hygiene&rft.issn=&rft_id=info:doi/ L2 - http://www.astmh.org/AM/Template.cfm?Section=Meeting_Archives&Template =/CM/ContentDisplay.cfm&ContentID=2309 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Seroprevalence of Dengue in United States Army Special Operations Command Personnel T2 - 58th Annual Meeting of the American Society of Tropical Medicine and Hygiene AN - 42223328; 5592121 JF - 58th Annual Meeting of the American Society of Tropical Medicine and Hygiene AU - Caci, Jennifer AU - Tack, Danielle AU - Lyons, Arthur Y1 - 2009/11/18/ PY - 2009 DA - 2009 Nov 18 KW - USA KW - Dengue KW - Personnel KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42223328?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Journal+of+the+Acoustical+Society+of+America&rft.atitle=A+localization+algorithm+based+on+head-related+transfer+functions.&rft.au=Macdonald%2C+Justin+A&rft.aulast=Macdonald&rft.aufirst=Justin&rft.date=2008-06-01&rft.volume=123&rft.issue=6&rft.spage=4290&rft.isbn=&rft.btitle=&rft.title=The+Journal+of+the+Acoustical+Society+of+America&rft.issn=00014966&rft_id=info:doi/ L2 - http://www.astmh.org/AM/Template.cfm?Section=Meeting_Archives&Template =/CM/ContentDisplay.cfm&ContentID=2309 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Epstein Barr Viral Load and Antibodies in Children with Malaria T2 - 58th Annual Meeting of the American Society of Tropical Medicine and Hygiene AN - 42219246; 5591271 JF - 58th Annual Meeting of the American Society of Tropical Medicine and Hygiene AU - Otiende, Moses Y1 - 2009/11/18/ PY - 2009 DA - 2009 Nov 18 KW - Children KW - Malaria KW - Antibodies KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42219246?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=58th+Annual+Meeting+of+the+American+Society+of+Tropical+Medicine+and+Hygiene&rft.atitle=Epstein+Barr+Viral+Load+and+Antibodies+in+Children+with+Malaria&rft.au=Otiende%2C+Moses&rft.aulast=Otiende&rft.aufirst=Moses&rft.date=2009-11-18&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=58th+Annual+Meeting+of+the+American+Society+of+Tropical+Medicine+and+Hygiene&rft.issn=&rft_id=info:doi/ L2 - http://www.astmh.org/AM/Template.cfm?Section=Meeting_Archives&Template =/CM/ContentDisplay.cfm&ContentID=2309 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Evaluation of Novel Dipstick Assays for the Detection of Rift Valley Fever Virus in Mosquitoes T2 - 58th Annual Meeting of the American Society of Tropical Medicine and Hygiene AN - 42217756; 5591584 JF - 58th Annual Meeting of the American Society of Tropical Medicine and Hygiene AU - Turell, Michael AU - Dave, Kirti AU - Dave, Sonia AU - Mayda, Maria AU - Parker, Zahra AU - Coleman, Russell AU - Strickman, Daniel Y1 - 2009/11/18/ PY - 2009 DA - 2009 Nov 18 KW - Rift valleys KW - Rift Valley fever KW - Public health KW - Aquatic insects KW - Rift Valley fever virus KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42217756?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=58th+Annual+Meeting+of+the+American+Society+of+Tropical+Medicine+and+Hygiene&rft.atitle=Evaluation+of+Novel+Dipstick+Assays+for+the+Detection+of+Rift+Valley+Fever+Virus+in+Mosquitoes&rft.au=Turell%2C+Michael%3BDave%2C+Kirti%3BDave%2C+Sonia%3BMayda%2C+Maria%3BParker%2C+Zahra%3BColeman%2C+Russell%3BStrickman%2C+Daniel&rft.aulast=Turell&rft.aufirst=Michael&rft.date=2009-11-18&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=58th+Annual+Meeting+of+the+American+Society+of+Tropical+Medicine+and+Hygiene&rft.issn=&rft_id=info:doi/ L2 - http://www.astmh.org/AM/Template.cfm?Section=Meeting_Archives&Template =/CM/ContentDisplay.cfm&ContentID=2309 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Antigenic and Phylogenetic Analysis of Influenza Viruses in Kenya from 2006-08 within the Context of Regional and Global Influenza Drift T2 - 58th Annual Meeting of the American Society of Tropical Medicine and Hygiene AN - 42213382; 5590946 JF - 58th Annual Meeting of the American Society of Tropical Medicine and Hygiene AU - Schnabel, David AU - Bulimo, Wallace AU - Achilla, Rachel AU - Gibbons, Tom AU - Gordon, Scott Y1 - 2009/11/18/ PY - 2009 DA - 2009 Nov 18 KW - Kenya KW - Influenza KW - Viruses KW - Phylogenetics KW - Drift KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42213382?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=58th+Annual+Meeting+of+the+American+Society+of+Tropical+Medicine+and+Hygiene&rft.atitle=Antigenic+and+Phylogenetic+Analysis+of+Influenza+Viruses+in+Kenya+from+2006-08+within+the+Context+of+Regional+and+Global+Influenza+Drift&rft.au=Schnabel%2C+David%3BBulimo%2C+Wallace%3BAchilla%2C+Rachel%3BGibbons%2C+Tom%3BGordon%2C+Scott&rft.aulast=Schnabel&rft.aufirst=David&rft.date=2009-11-18&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=58th+Annual+Meeting+of+the+American+Society+of+Tropical+Medicine+and+Hygiene&rft.issn=&rft_id=info:doi/ L2 - http://www.astmh.org/AM/Template.cfm?Section=Meeting_Archives&Template =/CM/ContentDisplay.cfm&ContentID=2309 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Design and fabrication of a substrate integrated phase change thermal buffer heat sink T2 - 2009 ASME International Mechanical Engineering Congress and Exposition (IMECE 2009) AN - 42159405; 5553849 JF - 2009 ASME International Mechanical Engineering Congress and Exposition (IMECE 2009) AU - Jankowski, Nicholas AU - Morgan, Brian AU - McCluskey, Patrick Y1 - 2009/11/13/ PY - 2009 DA - 2009 Nov 13 KW - Buffers KW - Heat KW - Heat sinks KW - Phase changes KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42159405?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+ASME+International+Mechanical+Engineering+Congress+and+Exposition+%28IMECE+2009%29&rft.atitle=Design+and+fabrication+of+a+substrate+integrated+phase+change+thermal+buffer+heat+sink&rft.au=Jankowski%2C+Nicholas%3BMorgan%2C+Brian%3BMcCluskey%2C+Patrick&rft.aulast=Jankowski&rft.aufirst=Nicholas&rft.date=2009-11-13&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+ASME+International+Mechanical+Engineering+Congress+and+Exposition+%28IMECE+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.asmeconferences.org/Congress09/TechnicalProgramOverview.cfm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Improving Turret Control on Military Vehicles T2 - 2009 ASME International Mechanical Engineering Congress and Exposition (IMECE 2009) AN - 42148760; 5554441 JF - 2009 ASME International Mechanical Engineering Congress and Exposition (IMECE 2009) AU - Anderson, Thomas AU - Clark, Nathaniel AU - Kotz, Wesley AU - Stremick, Briana AU - Arnas, Ozer AU - Tamm, Gunnar AU - Ingold, Kirk AU - Kiel, Thomas Y1 - 2009/11/13/ PY - 2009 DA - 2009 Nov 13 KW - Military KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42148760?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+ASME+International+Mechanical+Engineering+Congress+and+Exposition+%28IMECE+2009%29&rft.atitle=Improving+Turret+Control+on+Military+Vehicles&rft.au=Anderson%2C+Thomas%3BClark%2C+Nathaniel%3BKotz%2C+Wesley%3BStremick%2C+Briana%3BArnas%2C+Ozer%3BTamm%2C+Gunnar%3BIngold%2C+Kirk%3BKiel%2C+Thomas&rft.aulast=Anderson&rft.aufirst=Thomas&rft.date=2009-11-13&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+ASME+International+Mechanical+Engineering+Congress+and+Exposition+%28IMECE+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.asmeconferences.org/Congress09/TechnicalProgramOverview.cfm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Materials Considerations for Improved Flash/Flame Protection of Soldiers T2 - 2009 ASME International Mechanical Engineering Congress and Exposition (IMECE 2009) AN - 42144894; 5553628 JF - 2009 ASME International Mechanical Engineering Congress and Exposition (IMECE 2009) AU - Paquin, Jeremy AU - Martinez, Francisco AU - Hitt, Joseph AU - Arnas, Ozer Y1 - 2009/11/13/ PY - 2009 DA - 2009 Nov 13 KW - Military KW - Soldiers KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42144894?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+ASME+International+Mechanical+Engineering+Congress+and+Exposition+%28IMECE+2009%29&rft.atitle=Materials+Considerations+for+Improved+Flash%2FFlame+Protection+of+Soldiers&rft.au=Paquin%2C+Jeremy%3BMartinez%2C+Francisco%3BHitt%2C+Joseph%3BArnas%2C+Ozer&rft.aulast=Paquin&rft.aufirst=Jeremy&rft.date=2009-11-13&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+ASME+International+Mechanical+Engineering+Congress+and+Exposition+%28IMECE+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.asmeconferences.org/Congress09/TechnicalProgramOverview.cfm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Nanoengineering Polyaniline for Advanced Chemosensing Applications T2 - 2009 ASME International Mechanical Engineering Congress and Exposition (IMECE 2009) AN - 42141031; 5555066 JF - 2009 ASME International Mechanical Engineering Congress and Exposition (IMECE 2009) AU - Haynes, Aisha AU - Gouma, Perena Y1 - 2009/11/13/ PY - 2009 DA - 2009 Nov 13 KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42141031?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+ASME+International+Mechanical+Engineering+Congress+and+Exposition+%28IMECE+2009%29&rft.atitle=Nanoengineering+Polyaniline+for+Advanced+Chemosensing+Applications&rft.au=Haynes%2C+Aisha%3BGouma%2C+Perena&rft.aulast=Haynes&rft.aufirst=Aisha&rft.date=2009-11-13&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+ASME+International+Mechanical+Engineering+Congress+and+Exposition+%28IMECE+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.asmeconferences.org/Congress09/TechnicalProgramOverview.cfm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A Comparison of Coupling Molecular Dynamics to General Finite Elements T2 - 2009 ASME International Mechanical Engineering Congress and Exposition (IMECE 2009) AN - 42139741; 5555057 JF - 2009 ASME International Mechanical Engineering Congress and Exposition (IMECE 2009) AU - Macri, Michael Y1 - 2009/11/13/ PY - 2009 DA - 2009 Nov 13 KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42139741?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+ASME+International+Mechanical+Engineering+Congress+and+Exposition+%28IMECE+2009%29&rft.atitle=A+Comparison+of+Coupling+Molecular+Dynamics+to+General+Finite+Elements&rft.au=Macri%2C+Michael&rft.aulast=Macri&rft.aufirst=Michael&rft.date=2009-11-13&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+ASME+International+Mechanical+Engineering+Congress+and+Exposition+%28IMECE+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.asmeconferences.org/Congress09/TechnicalProgramOverview.cfm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Examining the Evaluability of Knowledge Management Initiatives T2 - 2009 Annual Conference of the American Evaluation Association (Evaluation 2009) AN - 42286711; 5624941 JF - 2009 Annual Conference of the American Evaluation Association (Evaluation 2009) AU - Ward II, Thomas Y1 - 2009/11/11/ PY - 2009 DA - 2009 Nov 11 KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42286711?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Annual+Conference+of+the+American+Evaluation+Association+%28Evaluation+2009%29&rft.atitle=Examining+the+Evaluability+of+Knowledge+Management+Initiatives&rft.au=Ward+II%2C+Thomas&rft.aulast=Ward+II&rft.aufirst=Thomas&rft.date=2009-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Annual+Conference+of+the+American+Evaluation+Association+%28Evaluation+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.eval.org/search09/allschedule.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - The Chicken and the Egg: Integrating Program Evaluation Plans Into Curriculum Design T2 - 2009 Annual Conference of the American Evaluation Association (Evaluation 2009) AN - 42278206; 5624533 JF - 2009 Annual Conference of the American Evaluation Association (Evaluation 2009) AU - Risner, Rhoda AU - Williams, Llinda Y1 - 2009/11/11/ PY - 2009 DA - 2009 Nov 11 KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42278206?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Annual+Conference+of+the+American+Evaluation+Association+%28Evaluation+2009%29&rft.atitle=The+Chicken+and+the+Egg%3A+Integrating+Program+Evaluation+Plans+Into+Curriculum+Design&rft.au=Risner%2C+Rhoda%3BWilliams%2C+Llinda&rft.aulast=Risner&rft.aufirst=Rhoda&rft.date=2009-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Annual+Conference+of+the+American+Evaluation+Association+%28Evaluation+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.eval.org/search09/allschedule.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - The Intersection of Race and Gender in the Ivory Tower: Evaluating Academic Life for Women of Color T2 - 2009 Annual Conference of the American Evaluation Association (Evaluation 2009) AN - 42276029; 5623598 JF - 2009 Annual Conference of the American Evaluation Association (Evaluation 2009) AU - Farris, Kimberly Y1 - 2009/11/11/ PY - 2009 DA - 2009 Nov 11 KW - Sex KW - Races KW - Color KW - Subpopulations KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42276029?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Annual+Conference+of+the+American+Evaluation+Association+%28Evaluation+2009%29&rft.atitle=The+Intersection+of+Race+and+Gender+in+the+Ivory+Tower%3A+Evaluating+Academic+Life+for+Women+of+Color&rft.au=Farris%2C+Kimberly&rft.aulast=Farris&rft.aufirst=Kimberly&rft.date=2009-11-11&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Annual+Conference+of+the+American+Evaluation+Association+%28Evaluation+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.eval.org/search09/allschedule.asp LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Missouri River Recovery Program: Progress and Challenges in Creating Shallow Water Habitat for the Endangered Pallid Sturgeon T2 - 2009 AWRA Annual Water Resources Conference AN - 42050275; 5507515 JF - 2009 AWRA Annual Water Resources Conference AU - Gossenauer, Michael Y1 - 2009/11/09/ PY - 2009 DA - 2009 Nov 09 KW - USA, Missouri R. KW - Shallow water KW - Habitat KW - Rivers KW - Rare species KW - Acipenser KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42050275?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+AWRA+Annual+Water+Resources+Conference&rft.atitle=Missouri+River+Recovery+Program%3A+Progress+and+Challenges+in+Creating+Shallow+Water+Habitat+for+the+Endangered+Pallid+Sturgeon&rft.au=Gossenauer%2C+Michael&rft.aulast=Gossenauer&rft.aufirst=Michael&rft.date=2009-11-09&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+AWRA+Annual+Water+Resources+Conference&rft.issn=&rft_id=info:doi/ L2 - http://www.awra.org/meetings/Seattle2009/doc/AWRA-SEA-Final-Program-20 09.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Pervious Concrete Specification Progress T2 - 2009 ACI Conference on Material Science Modeling AN - 42526480; 5450063 JF - 2009 ACI Conference on Material Science Modeling AU - Weiss Jr, Charles AU - Poole, Toy AU - Offenberg, Matthew Y1 - 2009/11/08/ PY - 2009 DA - 2009 Nov 08 KW - Concrete KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42526480?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+ACI+Conference+on+Material+Science+Modeling&rft.atitle=Pervious+Concrete+Specification+Progress&rft.au=Weiss+Jr%2C+Charles%3BPoole%2C+Toy%3BOffenberg%2C+Matthew&rft.aulast=Weiss+Jr&rft.aufirst=Charles&rft.date=2009-11-08&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+ACI+Conference+on+Material+Science+Modeling&rft.issn=&rft_id=info:doi/ L2 - http://www.concrete.org/Convention/fall-Convention/images/New%20Orlean s/NO-ProgramBook.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Reactivity of Singlet Oxygen Generated Using Nanoporous Silicon for Transformation of Acrylonitrile T2 - 2009 AIChE Annual Meeting (AIChE 2009) AN - 42172865; 5569935 JF - 2009 AIChE Annual Meeting (AIChE 2009) AU - Boddu, Veera AU - Worku, Deereje AU - Cropek, Donald Y1 - 2009/11/08/ PY - 2009 DA - 2009 Nov 08 KW - Silicon KW - Oxygen KW - Acrylonitrile KW - Transformation KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42172865?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+AIChE+Annual+Meeting+%28AIChE+2009%29&rft.atitle=Reactivity+of+Singlet+Oxygen+Generated+Using+Nanoporous+Silicon+for+Transformation+of+Acrylonitrile&rft.au=Boddu%2C+Veera%3BWorku%2C+Deereje%3BCropek%2C+Donald&rft.aulast=Boddu&rft.aufirst=Veera&rft.date=2009-11-08&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+AIChE+Annual+Meeting+%28AIChE+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://aiche.confex.com/aiche/2009/webprogram/meeting.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Disulfides as Cyanide Antidotes: Evidence for a New In Vivo Oxidative Pathway for Cyanide Detoxification AN - 754549232; 13301132 AB - It is known that cyanide is converted to thiocyanate in the presence of the enzyme rhodanese. The enzyme is activated by sulfur transfer from an appropriate sulfur donor. The activated enzyme then binds cyanide and transfers the sulfur atom to cyanide to form thiocyanate. This project began as an exploration of the ability of disulfides to act as sulfur donors in the rhodanese-mediated detoxification of cyanide. To our surprise, and contrary to expectations based on efficacy studies in vivo, our in vitro results showed that disulfides are rather poor sulfur donors. The transfer of a sulfur atom from a disulfide to the enzyme must occur via cleavage of a carbon-sulfur bond either of the original disulfide or in a mixed disulfide arising from the reaction of rhodanese with the original disulfide. Extending the reaction time and addition of chloride anion (a nucleophile) did not significantly change the results of the experiment. Using ultrasound as a means of accelerating bond cleavage also had a minimal effect. Those results ruled out cleavage of the carbon-sulfur bond in the original disulfide but did not preclude formation of a mixed disulfide. S-Methyl methylthiosulfonate (MTSO) was used to determine whether a mixed disulfide, if formed, would result in transfer of a sulfur atom to rhodanese. While no thiocyanate was formed in the reaction between cyanide and rhodanese exposed to MTSO, NMR analysis revealed that MTSO reacted directly with cyanide anion to form methyl thiocyanate. This result reveals the body's possible use of oxidized disulfides as a first line of defense against cyanide intoxication. The oxidation of disulfides to the corresponding thiosulfinate or thiosulfonate will result in facilitating their reaction with other nucleophiles. The reaction of an oxidized disulfide with a sulfur nucleophile from glutathione could be a plausible origin for the cyanide metabolite 2-aminothiazoline-4-carboxylic acid. JF - Chemical Research in Toxicology AU - Zottola, Mark A AU - Beigel, Keith AU - Soni, Sunil-Datta AU - Lawrence, Richard AD - United States Army Medical Research Institute of Chemical Defense, 3100 Ricketts Point Road, Edgewood Area-Aberdeen Proving Ground, Maryland 21010, and Department of Chemistry, University of Alabama at Birmingham, 1530 Third Avenue South, Birmingham, Alabama 35294 Y1 - 2009/11/05/ PY - 2009 DA - 2009 Nov 05 SP - 1948 EP - 1953 PB - American Chemical Society, P.O. Box 182426 Columbus OH 43218-2426 USA VL - 22 IS - 12 SN - 0893-228X, 0893-228X KW - Toxicology Abstracts; Biotechnology and Bioengineering Abstracts KW - Intoxication KW - Detoxification KW - Sulfur KW - Anions KW - Glutathione KW - Enzymes KW - Chloride KW - Metabolites KW - Nucleophiles KW - Mixed disulfides KW - Cyanide KW - Oxidation KW - N.M.R. KW - Ultrasound KW - rhodanese KW - Antidotes KW - W 30910:Imaging KW - X 24330:Agrochemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754549232?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemical+Research+in+Toxicology&rft.atitle=Disulfides+as+Cyanide+Antidotes%3A+Evidence+for+a+New+In+Vivo+Oxidative+Pathway+for+Cyanide+Detoxification&rft.au=Zottola%2C+Mark+A%3BBeigel%2C+Keith%3BSoni%2C+Sunil-Datta%3BLawrence%2C+Richard&rft.aulast=Zottola&rft.aufirst=Mark&rft.date=2009-11-05&rft.volume=22&rft.issue=12&rft.spage=1948&rft.isbn=&rft.btitle=&rft.title=Chemical+Research+in+Toxicology&rft.issn=0893228X&rft_id=info:doi/10.1021%2Ftx900258m LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2016-05-27 N1 - SubjectsTermNotLitGenreText - Sulfur; Detoxification; Intoxication; Anions; Glutathione; Enzymes; Metabolites; Chloride; Nucleophiles; Mixed disulfides; Cyanide; Oxidation; N.M.R.; Ultrasound; Antidotes; rhodanese DO - http://dx.doi.org/10.1021/tx900258m ER - TY - JOUR T1 - Botulism and vaccines for its prevention. AN - 734093044; 19837283 AB - Botulism is a severe neuroparalytic disease caused by toxins produced by several Clostridium species. Botulinum toxin has been of concern to the US military and its allies as a biowarfare weapon since World War II and, in more recent times, by the Centers for Disease Control and Prevention (CDC) as a potential bioterrorist threat to the public. The most effective means of defending against the toxin is by inducing a protective immune response through vaccination. Vaccination with an appropriate antigen will produce neutralizing antibodies that will bind to and clear toxin from the circulation before it can enter nerve cells and block neurotransmission. Immunity from botulism, however, has the disadvantage of precluding an individual from realizing the potential benefits of therapeutic botulinum toxin, if such a need were to arise. Botulinum toxin has been used in the treatment of numerous neuromuscular, autonomic, and sensory disorders since it was first approved for the management of strabismus and blepharospasm by the Food and Drug Administration (FDA) in 1989. Notwithstanding the value of the neurotoxin as a therapeutic drug, vaccines have been and will continue to be an important line of defense for those who work with the toxin (at-risk workers) and a select population of the military, law enforcement, and first responders. The first vaccine used to protect against botulinum neurotoxin was a chemically detoxified extract from Clostridium botulinum. A Pentavalent botulinum toxoid (PBT) vaccine in service today is administered under an Investigational New Drug (IND) application held by the CDC. Recombinant subunit vaccines are in development and a bivalent H(c) vaccine (rBV A/B (Pichia pastoris)) is presently being evaluated in a phase II clinical trial. This review focuses on botulism and the development of vaccines for its prevention. JF - Vaccine AU - Smith, Leonard A AD - Medical Countermeasures Technology, U.S. Army Medical Research and Materiel Command, Fort Detrick, MD 21702-5011, United States of America. Leonard.Smith@amedd.army.mil Y1 - 2009/11/05/ PY - 2009 DA - 2009 Nov 05 SP - D33 EP - D39 VL - 27 Suppl 4 KW - Bacterial Vaccines KW - 0 KW - Biological Warfare Agents KW - Vaccines, Synthetic KW - Botulinum Toxins KW - EC 3.4.24.69 KW - Index Medicus KW - Botulinum Toxins -- immunology KW - Humans KW - Vaccines, Synthetic -- immunology KW - Biological Warfare -- prevention & control KW - Clostridium botulinum -- immunology KW - Bacterial Vaccines -- immunology KW - Botulism -- prevention & control KW - Botulism -- immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/734093044?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Botulism+and+vaccines+for+its+prevention.&rft.au=Smith%2C+Leonard+A&rft.aulast=Smith&rft.aufirst=Leonard&rft.date=2009-11-05&rft.volume=27+Suppl+4&rft.issue=&rft.spage=D33&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=1873-2518&rft_id=info:doi/10.1016%2Fj.vaccine.2009.08.059 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-11-23 N1 - Date created - 2009-10-19 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.vaccine.2009.08.059 ER - TY - JOUR T1 - A naturalistic approach to assessing hearing aid candidacy and motivating hearing aid use. AN - 742786063; pmid-20503799 AB - Although the benefits of amplification for persons with impaired hearing are well established, many potential candidates do not obtain and use hearing aids. In some cases, this is because the individual is not convinced that amplification will be of sufficient benefit in those everyday listening situations where he or she is experiencing difficulties.To describe the development of a naturalistic approach to assessing hearing aid candidacy and motivating hearing aid use based on patient preferences for unamplified and amplified sound samples typical of those encountered in everyday living and to assess the validity of these preference ratings to predict hearing aid candidacy.Prospective experimental study comparing preference ratings for unamplified and amplified sound samples of patients with a clinical recommendation for hearing aid use and patients for whom amplification was not prescribed.Forty-eight adults self-referred to the Army Audiology and Speech Center for a hearing evaluation.Unamplified and amplified sound samples were presented to potential hearing aid candidates using a three-alternative forced-choice paradigm. Participants were free to switch at will among the three processing options (no gain, mild gain, moderate gain) until the preferred option was determined. Following this task, each participant was seen for a diagnostic hearing evaluation by one of eight staff audiologists with no knowledge of the preference data. Patient preferences for the three processing options were used to predict the attending audiologists' recommendations for amplification based on traditional audiometric measures.Hearing aid candidacy was predicted with moderate accuracy from the patients' preferences for amplified sounds typical of those encountered in everyday living, although the predictive validity of the various sound samples varied widely.Preferences for amplified sounds were generally predictive of hearing aid candidacy. However, the predictive validity of the preference ratings was not sufficient to replace traditional clinical determinations of hearing aid candidacy in individual patients. Because the sound samples are common to patients' everyday listening experiences, they provide a quick and intuitive method of demonstrating the potential benefit of amplification to patients who might otherwise not accept a prescription for hearing aids. JF - Journal of the American Academy of Audiology AU - Walden, Therese C AU - Walden, Brian E AU - Summers, Van AU - Grant, Ken W AD - Army Audiology and Speech Center, Walter Reed Army Medical Center, Washington, DC 20307-5001, USA. therese.walden@amedd.army.mil Y1 - 2009/11// PY - 2009 DA - Nov 2009 SP - 607 EP - 620 VL - 20 IS - 10 SN - 1050-0545, 1050-0545 KW - Index Medicus KW - National Library of Medicine KW - Activities of Daily Living KW - Adult KW - Child KW - Choice Behavior KW - *Directive Counseling: methods KW - Female KW - *Hearing Aids KW - *Hearing Loss: psychology KW - *Hearing Loss: rehabilitation KW - Humans KW - Male KW - *Motivation KW - *Patient Acceptance of Health Care KW - Patient Selection KW - Prospective Studies KW - Reproducibility of Results KW - Task Performance and Analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742786063?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+the+American+Academy+of+Audiology&rft.atitle=A+naturalistic+approach+to+assessing+hearing+aid+candidacy+and+motivating+hearing+aid+use.&rft.au=Walden%2C+Therese+C%3BWalden%2C+Brian+E%3BSummers%2C+Van%3BGrant%2C+Ken+W&rft.aulast=Walden&rft.aufirst=Therese&rft.date=2009-11-01&rft.volume=20&rft.issue=10&rft.spage=607&rft.isbn=&rft.btitle=&rft.title=Journal+of+the+American+Academy+of+Audiology&rft.issn=10500545&rft_id=info:doi/ LA - English (eng) DB - ComDisDome N1 - Date revised - 2011-12-15 N1 - Last updated - 2012-07-13 ER - TY - JOUR T1 - HIV positivity, protease inhibitor exposure and subclinical atherosclerosis: a systematic review and meta-analysis of observational studies. AN - 734114836; 19632982 AB - Patients with HIV may have increased risk of atherosclerotic cardiovascular disease owing to multiple biological mechanisms. To evaluate the evidence for subclinical atherosclerosis among patients with HIV. Systematic review of observational studies. We searched Medline, Cochrane DSR, ACP Journal Club, DARE, CMR, HTA, NHSEED, Embase and the Cochrane Controlled Trials Register for studies published before November 2008. Eligible studies were cross-sectional, cohort, or case-control studies reporting carotid ultrasound intima-media thickness (CIMT), focal plaque incidence, or coronary artery calcium (CAC), as determined by HIV positivity or protease inhibitor (PI) exposure. Two independent reviewers abstracted data using a standardised form. The primary outcome was weighted mean difference (WMD) for CIMT comparing HIV positive versus negative patients. Other outcomes included WMD by PI exposure and the odds ratio (OR) for a focal carotid plaque or CAC. Data from six cross-sectional, seven case-control and 13 cohort studies were included, involving 5456 HIV positive and 3600 HIV negative patients. The weighted mean CIMT was 0.04 mm thicker among patients with HIV than among non-HIV patients (95% CI 0.02 to 0.06; p<0.001). HIV positivity was not associated with carotid plaque or CAC. PI exposure did not significantly affect CIMT, carotid plaque, or CAC. There was evidence of publication bias and stratified analysis and meta-regression showed outcomes were influenced by study design, age, gender and smoking. However, HIV positivity slightly increased CIMT even after sensitivity analyses. HIV infection and PI exposure are not strong independent risk factors for subclinical atherosclerosis. Confounding may contribute to overestimation of the risk associated with HIV and PI exposure. JF - Heart (British Cardiac Society) AU - Hulten, E AU - Mitchell, J AU - Scally, J AU - Gibbs, B AU - Villines, T C AD - Department of Cardiology, Walter Reed Army Medical Center, 6900 Georgia Ave NW, Washington DC 20307, USA. edward.hulten@amedd.army.mil Y1 - 2009/11// PY - 2009 DA - November 2009 SP - 1826 EP - 1835 VL - 95 IS - 22 KW - Protease Inhibitors KW - 0 KW - Abridged Index Medicus KW - Index Medicus KW - Calcinosis -- pathology KW - Epidemiologic Methods KW - Humans KW - Adult KW - Calcinosis -- chemically induced KW - Calcinosis -- virology KW - Tunica Intima -- pathology KW - Male KW - Female KW - Protease Inhibitors -- adverse effects KW - Coronary Artery Disease -- virology KW - Carotid Artery Diseases -- pathology KW - HIV Infections -- complications KW - Carotid Artery Diseases -- virology KW - HIV Infections -- drug therapy KW - Coronary Artery Disease -- chemically induced KW - Coronary Artery Disease -- pathology KW - Carotid Artery Diseases -- chemically induced UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/734114836?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Heart+%28British+Cardiac+Society%29&rft.atitle=HIV+positivity%2C+protease+inhibitor+exposure+and+subclinical+atherosclerosis%3A+a+systematic+review+and+meta-analysis+of+observational+studies.&rft.au=Hulten%2C+E%3BMitchell%2C+J%3BScally%2C+J%3BGibbs%2C+B%3BVillines%2C+T+C&rft.aulast=Hulten&rft.aufirst=E&rft.date=2009-11-01&rft.volume=95&rft.issue=22&rft.spage=1826&rft.isbn=&rft.btitle=&rft.title=Heart+%28British+Cardiac+Society%29&rft.issn=1468-201X&rft_id=info:doi/10.1136%2Fhrt.2009.177774 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-12-21 N1 - Date created - 2009-10-30 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1136/hrt.2009.177774 ER - TY - JOUR T1 - Acute phosphate nephropathy. AN - 734088641; 19636249 AB - Acute phosphate nephropathy (APN) has been identified in renal biopsy specimens of patients exposed to oral sodium phosphate (OSP) bowel purgatives. Biopsy confirmed cases presented with bland urinary sediment, low-grade proteinuria, and varying degrees of creatinine elevation. Prospective identification of APN is difficult in that definitive diagnosis requires renal biopsy, and biopsy is rarely performed for patients with this clinical presentation. Observational studies evaluating acute kidney injury after OSP exposure using interval changes in creatinine as a surrogate for APN have reported conflicting results. Although these studies have produced estimates of disease occurrence, they have been unable to definitively quantify the overall risk of APN with OSP as compared with alternative bowel-cleansing agents. On the basis of association of APN and OSP, the US Food and Drug Administration issued a boxed warning and manufacturers have ceased production and distribution of some OSP products. As this is a temporary solution, more studies are needed to delineate the pathophysiology of this disease and to better identify the subset of the population at risk for APN. JF - Current opinion in nephrology and hypertension AU - Hurst, Frank P AU - Abbott, Kevin C AD - Nephrology Service, Walter Reed Army Medical Center, Washington, DC 20307, USA. frank.hurst@us.army.mil Y1 - 2009/11// PY - 2009 DA - November 2009 SP - 513 EP - 518 VL - 18 IS - 6 KW - Biomarkers KW - 0 KW - Calcium Phosphates KW - Cathartics KW - Phosphates KW - calcium phosphate KW - 97Z1WI3NDX KW - Creatinine KW - AYI8EX34EU KW - sodium phosphate KW - SE337SVY37 KW - Index Medicus KW - Acute Disease KW - Administration, Oral KW - United States KW - Humans KW - Biopsy KW - Creatinine -- blood KW - Risk Assessment KW - Safety-Based Drug Withdrawals KW - United States Food and Drug Administration KW - Up-Regulation KW - Calcium Phosphates -- analysis KW - Biomarkers -- blood KW - Drug Labeling KW - Proteinuria -- chemically induced KW - Kidney Diseases -- pathology KW - Cathartics -- adverse effects KW - Cathartics -- administration & dosage KW - Kidney -- pathology KW - Kidney Diseases -- blood KW - Kidney -- drug effects KW - Phosphates -- adverse effects KW - Kidney -- chemistry KW - Phosphates -- administration & dosage KW - Kidney Diseases -- chemically induced UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/734088641?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Current+opinion+in+nephrology+and+hypertension&rft.atitle=Acute+phosphate+nephropathy.&rft.au=Hurst%2C+Frank+P%3BAbbott%2C+Kevin+C&rft.aulast=Hurst&rft.aufirst=Frank&rft.date=2009-11-01&rft.volume=18&rft.issue=6&rft.spage=513&rft.isbn=&rft.btitle=&rft.title=Current+opinion+in+nephrology+and+hypertension&rft.issn=1473-6543&rft_id=info:doi/10.1097%2FMNH.0b013e32833096af LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-12-24 N1 - Date created - 2009-10-15 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1097/MNH.0b013e32833096af ER - TY - JOUR T1 - Transformation and the Irregular Gap AN - 58839618; 2008-443658 AB - America's difficulties in Iraq and Afghanistan have shaken discussions of transformation to their technological roots. The Defense Department (DOD) is beginning to realize that modernizing our Army for irregular conflicts in the 21st century will require profound changes in the human workforce. Yet, an "irregular gap" persists within the Army's current force structure. On 1 December 2008, DOD Directive 3000.07 established policy oversight to improve DOD proficiency for irregular warfare. The directive prescribes the Defense Department to be "as effective in irregular warfare as it is in traditional warfare." Yet, the Army has optimized its ground forces for strategic mobility and fluid, decisive, operational maneuver against state adversaries. The organizational transformation launched in 2003 has remained unscathed despite profound changes in national security imperatives, threat perceptions, and updated military doctrine. Transformation's initial assumptions, the Army's current organizational design, and recent strategic policy changes are incongruent. The Army's decision to expand its force with six additional brigade combat teams (BCTs) is essentially a "more-of-the-same" approach instead of making the force structure more capable given perceived future threats. Secretary Gates recently encouraged Army planners to be innovative in exploring "how the Army should be organized." This article is one attempt to do so. Adapted from the source document. JF - Military Review AU - Burgess, Kenneth J AD - U.S. Army Y1 - 2009/11// PY - 2009 DA - November 2009 SP - 25 EP - 34 PB - US Army Combined Arms Center, Leavenworth, KS VL - 89 IS - 6 SN - 0026-4148, 0026-4148 KW - Military and defense policy - Military planning, strategy, and operations KW - International relations - War KW - Politics - Political dissent and internal conflict KW - Military planning KW - Military operations KW - United States Army KW - Conflict KW - United States Defense department KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58839618?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Military+Review&rft.atitle=Transformation+and+the+Irregular+Gap&rft.au=Burgess%2C+Kenneth+J&rft.aulast=Burgess&rft.aufirst=Kenneth&rft.date=2009-11-01&rft.volume=89&rft.issue=6&rft.spage=25&rft.isbn=&rft.btitle=&rft.title=Military+Review&rft.issn=00264148&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2010-02-03 N1 - SuppNotes - http://usacac.army.mil/CAC2/MilitaryReview/Archives/English/MilitaryReview_ 20 091231_art006.pdf N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - United States Defense department; United States Army; Military planning; Military operations; Conflict ER - TY - JOUR T1 - Developing Creative and Critical Thinkers AN - 58829978; 2008-443660 AB - This article presents a definition of strategic thinking and then focuses on the two key antecedents of strategic thinking -- creative and critical thinking -- and presents the Army War College approach to educating students in these skills. Adapted from the source document. JF - Military Review AU - Allen, Charles D AU - Gerras, Stephen J AD - U.S. Army Y1 - 2009/11// PY - 2009 DA - November 2009 SP - 77 EP - 83 PB - US Army Combined Arms Center, Leavenworth, KS VL - 89 IS - 6 SN - 0026-4148, 0026-4148 KW - Labor conditions and policy - Employment and labor supply KW - Military and defense policy - Military planning, strategy, and operations KW - Military and defense policy - Military personnel and veterans KW - Military and defense policy - Military service KW - Human capital KW - United States army war college KW - Military training KW - Military operations KW - Armed forces KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58829978?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Military+Review&rft.atitle=Developing+Creative+and+Critical+Thinkers&rft.au=Allen%2C+Charles+D%3BGerras%2C+Stephen+J&rft.aulast=Allen&rft.aufirst=Charles&rft.date=2009-11-01&rft.volume=89&rft.issue=6&rft.spage=77&rft.isbn=&rft.btitle=&rft.title=Military+Review&rft.issn=00264148&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2010-02-03 N1 - SuppNotes - http://usacac.army.mil/CAC2/MilitaryReview/Archives/English/MilitaryReview_ 20 091231_art012.pdf N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Military operations; Armed forces; Human capital; Military training; United States army war college ER - TY - JOUR T1 - Dengue Plaque Reduction Neutralization Test (PRNT) in Primary and Secondary Dengue Virus Infections: How Alterations in Assay Conditions Impact Performance AN - 21273261; 11848100 AB - Dengue virus (DENV) infection is a worsening global health problem. The plaque reduction neutralization test (PRNT) is currently considered to be the "gold standard" to characterize and quantify circulating levels of anti-DENV neutralizing antibody (NAb). Many variations of the PRNT are currently in use and neither the assay nor its performance conditions have been standardized or harmonized between laboratories. We used a well-characterized panel of acute and late convalescent follow-up sera samples from children experiencing primary and secondary DENV infections to evaluate the performance of the dengue PRNT under a variety of testing conditions. Investigators varied cell type, control virus passage, and the use of complement across multiple assay runs of the same sample panel. Our findings indicate wide variation in PRNT titer results in response to varied testing conditions. JF - American Journal of Tropical Medicine and Hygiene AU - Thomas, S J AU - Nisalak, A AU - Anderson, K B AU - Libraty, D H AU - Kalayanarooj, S AU - Vaughn, D W AU - Putnak, R AU - Gibbons, R V AU - Jarman, R AU - Endy, T P AD - United States Army Medical Component, Armed Forces Research Institute of Medical Sciences, APO AP 96546, USA, Stephen.thomas@afrims.org Y1 - 2009/11// PY - 2009 DA - Nov 2009 VL - 81 IS - 5 SN - 0002-9637, 0002-9637 KW - Virology & AIDS Abstracts; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality KW - Dengue virus KW - Human diseases KW - Antibodies KW - Viral diseases KW - Dengue KW - Plaques KW - Infection KW - Children KW - Hygiene KW - Public health KW - Q5 01524:Public health, medicines, dangerous organisms KW - V 22400:Human Diseases KW - Q1 01484:Species interactions: parasites and diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21273261?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Dengue+Plaque+Reduction+Neutralization+Test+%28PRNT%29+in+Primary+and+Secondary+Dengue+Virus+Infections%3A+How+Alterations+in+Assay+Conditions+Impact+Performance&rft.au=Thomas%2C+S+J%3BNisalak%2C+A%3BAnderson%2C+K+B%3BLibraty%2C+D+H%3BKalayanarooj%2C+S%3BVaughn%2C+D+W%3BPutnak%2C+R%3BGibbons%2C+R+V%3BJarman%2C+R%3BEndy%2C+T+P&rft.aulast=Thomas&rft.aufirst=S&rft.date=2009-11-01&rft.volume=81&rft.issue=5&rft.spage=&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Antibodies; Human diseases; Viral diseases; Hygiene; Public health; Dengue; Plaques; Children; Infection; Dengue virus ER - TY - JOUR T1 - Predicting physical properties of emerging compounds with limited physical and chemical data: QSAR model uncertainty and applicability to military munitions AN - 21265629; 11300073 AB - Reliable, up-front information on physical and biological properties of emerging materials is essential before making a decision and investment to formulate, synthesize, scale-up, test, and manufacture a new material for use in both military and civilian applications. Multiple quantitative structure-activity relationships (QSARs) software tools are available for predicting a material's physical/chemical properties and environmental effects. Even though information on emerging materials is often limited, QSAR software output is treated without sufficient uncertainty analysis. We hypothesize that uncertainty and variability in material properties and uncertainty in model prediction can be too large to provide meaningful results. To test this hypothesis, we predicted octanol water partitioning coefficients (logP) for multiple, similar compounds with limited physical-chemical properties using six different commercial logP calculators (KOWWIN, MarvinSketch, ACD/Labs, ALogP, CLogP, SPARC). Analysis was done for materials with largely uncertain properties that were similar, based on molecular formula, to military compounds (RDX, BTTN, TNT) and pharmaceuticals (Carbamazepine, Gemfibrizol). We have also compared QSAR modeling results for a well-studied pesticide and pesticide breakdown product (Atrazine, DDE). Our analysis shows variability due to structural variations of the emerging chemicals may be several orders of magnitude. The model uncertainty across six software packages was very high (10 orders of magnitude) for emerging materials while it was low for traditional chemicals (e.g. Atrazine). Thus the use of QSAR models for emerging materials screening requires extensive model validation and coupling QSAR output with available empirical data and other relevant information. JF - Chemosphere AU - Bennett, E R AU - Clausen, J AU - Linkov, E AU - Linkov, I AD - Cold Regions Research and Engineering Laboratory, Hanover, NH, USA, Jay.L.Clausen@usace.army.mil Y1 - 2009/11// PY - 2009 DA - Nov 2009 SP - 1412 EP - 1418 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 77 IS - 10 SN - 0045-6535, 0045-6535 KW - Environment Abstracts KW - Computer programs KW - structure-activity relationships KW - Atrazine KW - Pesticides KW - DDE KW - Physicochemical properties KW - chemical properties KW - Herbicides KW - Military KW - ENA 09:Land Use & Planning UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21265629?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemosphere&rft.atitle=Predicting+physical+properties+of+emerging+compounds+with+limited+physical+and+chemical+data%3A+QSAR+model+uncertainty+and+applicability+to+military+munitions&rft.au=Bennett%2C+E+R%3BClausen%2C+J%3BLinkov%2C+E%3BLinkov%2C+I&rft.aulast=Bennett&rft.aufirst=E&rft.date=2009-11-01&rft.volume=77&rft.issue=10&rft.spage=1412&rft.isbn=&rft.btitle=&rft.title=Chemosphere&rft.issn=00456535&rft_id=info:doi/10.1016%2Fj.chemosphere.2009.09.003 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Computer programs; structure-activity relationships; Physicochemical properties; DDE; Pesticides; Atrazine; chemical properties; Herbicides; Military DO - http://dx.doi.org/10.1016/j.chemosphere.2009.09.003 ER - TY - JOUR T1 - Exercise Performance of Sea-Level Residents at 4300 m After 6 Days at 2200 m AN - 21221974; 11206596 AB - Partial acclimatization resulting from staging at moderate altitude reduces acute mountain sickness during rapid exposure to higher altitudes (e.g., 4300 m). Whether staging also benefits endurance performance has not yet been scientifically evaluated. Purpose: Determine the effectiveness of staging at 2200 m on time trial (TT) performance of unaccli-matized sea-level residents (SLR) during rapid exposure to 4300 m. There were 10 healthy men (mean #+ SE: 21 #+ 1 yrs) who performed 720 kJ cycle TT at SL and following ~2 h of exposure to 4300 m (459 Torr) before (ALT-1) and after (ALT-2) living for 6 d at 2200 m (601 Torr). Methods: Hemoglobin concentration ([Hb]), hematocrit (Hct), arterial oxygen saturation (S(a)O(2)), ratings of perceived exertion (RPE), and heart rate (HR) were measured before and during exercise. Results: Compared to SL (73 #+ 6 min), TT performance was impaired (P < 0.01) by 38.1 #+ 6 min at ALT-1, but only by 18.7 #+ 3 min at ALT-2. The 44 #+ 8% TT improvement at 4300 m was directly correlated with increases in exercise S(a)O(2) (R = 0.88, P < 0.03), but not to changes in [Hb] or Hct. In addition, RPE was lower (13 #+ 1 vs.16 #+ 1, P< 0.01) and HR remained at ~148 #+ 5 bpm despite performing the TT at a higher power output during ALT-2 than ALT-1 (120 #+ 7 vs.100 #+ 10 W, P < 0.01). Conclusion: Partial acclimatization resulting from staging attenuated the impairment in TT performance of SLR rapidly exposed to 4300 m. The close association between improved TT performance and changes in exercise S(a)O(2), compared to a lack of association with changes in [Hb] or Hct, suggest ventilatory acclimatization may have been the major factor contributing to the performance improvement. JF - Aviation, Space, and Environmental Medicine AU - Fulco, Charles S AU - Muza, Stephen R AU - Beidleman, Beth AU - Jones, Juli AU - Staab, Janet AU - Rock, Paul B AU - Cymerman, Allen AD - Thermal and Mountain Medicine Division, U.S. Army Research Institute of Environmental Medicine, Natick, MA 01760-5007 Y1 - 2009/11// PY - 2009 DA - Nov 2009 SP - 955 EP - 961 PB - Aerospace Medical Association, 320 S. Henry St. Alexandria VA 22314-3579 USA VL - 80 IS - 11 SN - 0095-6562, 0095-6562 KW - Physical Education Index KW - Hemoglobin KW - Measurement KW - Altitude KW - Exercise (intensity) KW - Acclimatization KW - Heart rate KW - Endurance KW - Performance KW - Exercise KW - PE 090:Sports Medicine & Exercise Sport Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21221974?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aviation%2C+Space%2C+and+Environmental+Medicine&rft.atitle=Exercise+Performance+of+Sea-Level+Residents+at+4300+m+After+6+Days+at+2200+m&rft.au=Fulco%2C+Charles+S%3BMuza%2C+Stephen+R%3BBeidleman%2C+Beth%3BJones%2C+Juli%3BStaab%2C+Janet%3BRock%2C+Paul+B%3BCymerman%2C+Allen&rft.aulast=Fulco&rft.aufirst=Charles&rft.date=2009-11-01&rft.volume=80&rft.issue=11&rft.spage=955&rft.isbn=&rft.btitle=&rft.title=Aviation%2C+Space%2C+and+Environmental+Medicine&rft.issn=00956562&rft_id=info:doi/10.3357%2FASEM.2540.2009 LA - English DB - Physical Education Index N1 - Date revised - 2009-12-01 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Hemoglobin; Measurement; Altitude; Exercise (intensity); Heart rate; Acclimatization; Endurance; Exercise; Performance DO - http://dx.doi.org/10.3357/ASEM.2540.2009 ER - TY - JOUR T1 - The association between use of spermicides or male condoms and major structural birth defects AN - 21133203; 11184624 AB - Women may become pregnant while using contraceptives. Commonly used contraceptives containing spermicides may or may not be associated with an increased occurrence of structural birth defects. Study Design - Utilizing data from the National Birth Defects Prevention Study, we assessed maternal reports of spermicide and male condom use 1 to 3 months following conception among case (n=11,050) and control (n=4723) mothers. We assessed the association between spermicide use and 27 types of birth defects and that between condom use and 32 types of birth defects. Results - Maternal spermicide use during the first 3 months following conception was associated with a significant increase in the occurrence of only 1 of 27 birth defects, perimembranous ventricular septal defects (adjusted odds ratio=2.40, 95% confidence interval=1.25-4.62). There was no significant association between maternal use of male condoms during the first 3 months following conception and any of 32 types of birth defects. Conclusions - The increased occurrence of perimembranous ventricular septal defects among spermicide users may be real or may be a chance finding. Overall, the findings are consistent with those of most previous studies that observed no increased risk for birth defects among spermicide users. JF - Contraception AU - Gallaway, MShayne AU - Waller, DKim AU - Canfield, Mark A AU - Scheuerle, Angela AD - School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA, shayne.gallaway@us.army.mil Y1 - 2009/11// PY - 2009 DA - Nov 2009 SP - 422 EP - 429 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 80 IS - 5 SN - 0010-7824, 0010-7824 KW - Health & Safety Science Abstracts; Risk Abstracts KW - contraceptives KW - prevention KW - Congenital defects KW - males KW - Pregnancy KW - condoms KW - R2 23060:Medical and environmental health KW - H 4000:Food and Drugs UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21133203?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Contraception&rft.atitle=The+association+between+use+of+spermicides+or+male+condoms+and+major+structural+birth+defects&rft.au=Gallaway%2C+MShayne%3BWaller%2C+DKim%3BCanfield%2C+Mark+A%3BScheuerle%2C+Angela&rft.aulast=Gallaway&rft.aufirst=MShayne&rft.date=2009-11-01&rft.volume=80&rft.issue=5&rft.spage=422&rft.isbn=&rft.btitle=&rft.title=Contraception&rft.issn=00107824&rft_id=info:doi/10.1016%2Fj.contraception.2009.03.007 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-11-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Congenital defects; condoms; contraceptives; prevention; Pregnancy; males DO - http://dx.doi.org/10.1016/j.contraception.2009.03.007 ER - TY - JOUR T1 - Outdoor weathering and dissolution of TNT and Tritonal AN - 21084036; 11300089 AB - Low-order detonations of military munitions scatter cm-sized chunks of high-explosives onto military range soils, where rainfall can dissolve and then transport the explosives to groundwater. We present 1year of mass-loss data obtained from cm-sized chunks of the frequently used explosives TNT (2,4,6-trinitrotoluene) and Tritonal (an 80:20 mixture of TNT and aluminum flakes) exposed outdoors to weather and dissolve under natural conditions. The explosive chunks rested on glass frits in individual funnels and all precipitation interacting with them was collected and analyzed. Mass balance data reveal that TNT in the water samples accounts for only about one-third of the TNT lost from the chunks. The creation of photo-transformation products on the solid chunks, and their subsequent dissolution or sublimation, probably accounts for the other two-thirds. Although these products cannot, as yet, be quantified they are intrinsic to the outdoor weathering and fate of TNT-based explosives. TNT in our water samples was not photo-transformed. Thus, we used the yearlong, dissolved-mass time-series to validate a drop-impingement dissolution model for TNT. The model used measured rainfall and air temperature data as input, and the results agreed remarkably well with TNT dissolved-mass time-series measured for the year. This model can estimate annual TNT influx into range soils using annual rainfall and particle-size distributions. Nevertheless, large uncertainties remain in the numbers and sizes of TNT particles scattered on military ranges and the identities and fates of the photo-transformation products. JF - Chemosphere AU - Taylor, S AU - Lever, J H AU - Fadden, J AU - Perron, N AU - Packer, B AD - 72 Lyme Road, Hanover, NH, United States, Susan.Taylor@usace.army.mil Y1 - 2009/11// PY - 2009 DA - Nov 2009 SP - 1338 EP - 1345 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 77 IS - 10 SN - 0045-6535, 0045-6535 KW - Toxicology Abstracts; Pollution Abstracts; Environment Abstracts KW - Water sampling KW - air temperature KW - Rainfall KW - Particulates KW - 2,4,6-trinitrotoluene KW - Air temperature KW - Models KW - Soil KW - sublimation KW - 2,4,6-Trinitrotoluene KW - Ground water KW - Weathering KW - Military KW - Weather KW - Data processing KW - time series analysis KW - Precipitation KW - weathering KW - Aluminum KW - Dissolution KW - Explosives KW - Groundwater KW - P 2000:FRESHWATER POLLUTION KW - X 24360:Metals KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21084036?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemosphere&rft.atitle=Outdoor+weathering+and+dissolution+of+TNT+and+Tritonal&rft.au=Taylor%2C+S%3BLever%2C+J+H%3BFadden%2C+J%3BPerron%2C+N%3BPacker%2C+B&rft.aulast=Taylor&rft.aufirst=S&rft.date=2009-11-01&rft.volume=77&rft.issue=10&rft.spage=1338&rft.isbn=&rft.btitle=&rft.title=Chemosphere&rft.issn=00456535&rft_id=info:doi/10.1016%2Fj.chemosphere.2009.09.040 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-12-01 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Weather; Data processing; Rainfall; Precipitation; Air temperature; Models; Soil; 2,4,6-Trinitrotoluene; Aluminum; Ground water; Dissolution; Weathering; Explosives; air temperature; Water sampling; time series analysis; Particulates; 2,4,6-trinitrotoluene; weathering; sublimation; Military; Groundwater DO - http://dx.doi.org/10.1016/j.chemosphere.2009.09.040 ER - TY - CPAPER T1 - Describing a multigraded resolution from a lattice T2 - 2009 Fall AMS Southeastern Meeting AN - 42098512; 5535667 JF - 2009 Fall AMS Southeastern Meeting AU - Beecher, Amanda AU - Clark, Timothy AU - Tchernev, Alexandre Y1 - 2009/10/30/ PY - 2009 DA - 2009 Oct 30 KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42098512?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Fall+AMS+Southeastern+Meeting&rft.atitle=Describing+a+multigraded+resolution+from+a+lattice&rft.au=Beecher%2C+Amanda%3BClark%2C+Timothy%3BTchernev%2C+Alexandre&rft.aulast=Beecher&rft.aufirst=Amanda&rft.date=2009-10-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Fall+AMS+Southeastern+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.ams.org/amsmtgs/2161_progfull.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - An efficient drug delivery vehicle for botulism countermeasure. AN - 733402608; 19860869 AB - Botulinum neurotoxin (BoNT) is the most potent poison known to mankind. Currently no antidote is available to rescue poisoned synapses. An effective medical countermeasure strategy would require developing a drug that could rescue poisoned neuromuscular synapses and include its efficient delivery specifically to poisoned presynaptic nerve terminals. Here we report a drug delivery strategy that could directly deliver toxin inhibitors into the intoxicated nerve terminal cytosol. A targeted delivery vehicle was developed for intracellular transport of emerging botulinum neurotoxin antagonists. The drug delivery vehicle consisted of the non-toxic recombinant heavy chain of botulinum neurotoxin-A coupled to a 10-kDa amino dextran via the heterobifunctional linker 3-(2-pyridylthio)-propionyl hydrazide. The heavy chain served to target botulinum neurotoxin-sensitive cells and promote internalization of the complex, while the dextran served as a platform to deliver model therapeutic molecules to the targeted neurons. Our results indicated that the drug delivery vehicle entry into neurons was via BoNT-A receptor mediated endocytosis. Once internalized into neurons, the drug carrier component separated from the drug delivery vehicle in a fashion similar to the separation of the BoNT-A light chain from the holotoxin. This drug delivery vehicle could be used to deliver BoNT-A antidotes into BoNT-A intoxicated cultured mouse spinal cord cells. An effective BoNT-based drug delivery vehicle can be used to directly deliver toxin inhibitors into intoxicated nerve terminal cytosol. This approach can potentially be utilized for targeted drug delivery to treat other neuronal and neuromuscular disorders. This report also provides new knowledge of endocytosis and exocytosis as well as of BoNT trafficking. JF - BMC pharmacology AU - Zhang, Peng AU - Ray, Radharaman AU - Singh, Bal Ram AU - Li, Dan AU - Adler, Michael AU - Ray, Prabhati AD - Division of Experimental Therapeutic, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA. peng.zhang3@us.army.mil Y1 - 2009/10/27/ PY - 2009 DA - 2009 Oct 27 SP - 12 VL - 9 KW - Dextrans KW - 0 KW - Recombinant Proteins KW - Botulinum Toxins, Type A KW - EC 3.4.24.69 KW - Index Medicus KW - Botulism -- drug therapy KW - Animals KW - Protein Structure, Secondary KW - Dextrans -- chemistry KW - Recombinant Proteins -- biosynthesis KW - Recombinant Proteins -- chemical synthesis KW - Botulism -- metabolism KW - Mice KW - Dextrans -- administration & dosage KW - Presynaptic Terminals -- metabolism KW - Pregnancy KW - Presynaptic Terminals -- drug effects KW - Cells, Cultured KW - Endocytosis -- drug effects KW - Mice, Inbred C57BL KW - Endocytosis -- physiology KW - Recombinant Proteins -- therapeutic use KW - Female KW - Drug Delivery Systems -- methods KW - Botulinum Toxins, Type A -- biosynthesis KW - Botulinum Toxins, Type A -- antagonists & inhibitors KW - Botulinum Toxins, Type A -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733402608?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=BMC+pharmacology&rft.atitle=An+efficient+drug+delivery+vehicle+for+botulism+countermeasure.&rft.au=Zhang%2C+Peng%3BRay%2C+Radharaman%3BSingh%2C+Bal+Ram%3BLi%2C+Dan%3BAdler%2C+Michael%3BRay%2C+Prabhati&rft.aulast=Zhang&rft.aufirst=Peng&rft.date=2009-10-27&rft.volume=9&rft.issue=&rft.spage=12&rft.isbn=&rft.btitle=&rft.title=BMC+pharmacology&rft.issn=1471-2210&rft_id=info:doi/10.1186%2F1471-2210-9-12 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-06-24 N1 - Date created - 2009-11-09 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: J Cell Biol. 1999 Dec 13;147(6):1249-60 [10601338] Life Sci. 2006 Jul 4;79(6):591-5 [16513141] JAMA. 2001 Feb 28;285(8):1059-70 [11209178] Am J Ther. 2002 Jan-Feb;9(1):5-14 [11782813] FEBS Lett. 2002 Feb 27;513(2-3):163-8 [11904143] Am J Med Sci. 2002 Jun;323(6):326-40 [12074487] Biochemistry. 2004 Jan 20;43(2):526-32 [14717608] Annu Rev Pharmacol Toxicol. 2004;44:167-93 [14744243] J Immunol Methods. 2004 May;288(1-2):55-60 [15183085] J Neurophysiol. 1987 Jan;57(1):121-31 [3031230] J Neurochem. 1992 Dec;59(6):2148-57 [1359016] Infect Immun. 1996 May;64(5):1589-94 [8613365] J Biol Chem. 1996 Mar 29;271(13):7694-9 [8631808] J Neurosci Res. 1996 May 1;44(3):263-71 [8723765] Q Rev Biophys. 1995 Nov;28(4):423-72 [8771234] Muscle Nerve. 1998 Jun;21(6):701-10 [9585323] Biochemistry. 1999 May 25;38(21):6903-10 [10346912] Toxicon. 2005 Mar 1;45(3):377-82 [15683877] Nat Struct Biol. 2000 Aug;7(8):617-9 [10932240] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1186/1471-2210-9-12 ER - TY - CPAPER T1 - A planar acoustic array for voice collection. T2 - 158th Meeting of The Acoustical Society of America AN - 42131552; 5538896 JF - 158th Meeting of The Acoustical Society of America AU - Gonski, David AU - Tran-Luu, Duong AU - Tenney, Stephen Y1 - 2009/10/26/ PY - 2009 DA - 2009 Oct 26 KW - Acoustic arrays KW - Acoustics KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42131552?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=158th+Meeting+of+The+Acoustical+Society+of+America&rft.atitle=A+planar+acoustic+array+for+voice+collection.&rft.au=Gonski%2C+David%3BTran-Luu%2C+Duong%3BTenney%2C+Stephen&rft.aulast=Gonski&rft.aufirst=David&rft.date=2009-10-26&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=158th+Meeting+of+The+Acoustical+Society+of+America&rft.issn=&rft_id=info:doi/ L2 - http://asa.aip.org/sanantonio/program.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Acoustic parameter estimates and confidence intervals for gravel at low frequencies T2 - 158th Meeting of The Acoustical Society of America AN - 42123991; 5539271 JF - 158th Meeting of The Acoustical Society of America AU - White, Michael AU - Swenson, Jr., George AU - Borrowman, Todd AU - Gertner, George Y1 - 2009/10/26/ PY - 2009 DA - 2009 Oct 26 KW - Acoustics KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42123991?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=158th+Meeting+of+The+Acoustical+Society+of+America&rft.atitle=Acoustic+parameter+estimates+and+confidence+intervals+for+gravel+at+low+frequencies&rft.au=White%2C+Michael%3BSwenson%2C+Jr.%2C+George%3BBorrowman%2C+Todd%3BGertner%2C+George&rft.aulast=White&rft.aufirst=Michael&rft.date=2009-10-26&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=158th+Meeting+of+The+Acoustical+Society+of+America&rft.issn=&rft_id=info:doi/ L2 - http://asa.aip.org/sanantonio/program.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Cost efficient sensor placement and configuration to fulfill spatially inhomogeneous coverage preferences T2 - 158th Meeting of The Acoustical Society of America AN - 42114963; 5538847 JF - 158th Meeting of The Acoustical Society of America AU - Vecherin, Sergey AU - Wilson, D AU - Pettit, Chris Y1 - 2009/10/26/ PY - 2009 DA - 2009 Oct 26 KW - Sensors KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42114963?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=158th+Meeting+of+The+Acoustical+Society+of+America&rft.atitle=Cost+efficient+sensor+placement+and+configuration+to+fulfill+spatially+inhomogeneous+coverage+preferences&rft.au=Vecherin%2C+Sergey%3BWilson%2C+D%3BPettit%2C+Chris&rft.aulast=Vecherin&rft.aufirst=Sergey&rft.date=2009-10-26&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=158th+Meeting+of+The+Acoustical+Society+of+America&rft.issn=&rft_id=info:doi/ L2 - http://asa.aip.org/sanantonio/program.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Sound propagation classes for long-range assessment algorithms T2 - 158th Meeting of The Acoustical Society of America AN - 42105570; 5538729 JF - 158th Meeting of The Acoustical Society of America AU - Swearingen, Michelle AU - White, Michael Y1 - 2009/10/26/ PY - 2009 DA - 2009 Oct 26 KW - Algorithms KW - Sound propagation KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42105570?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=158th+Meeting+of+The+Acoustical+Society+of+America&rft.atitle=Sound+propagation+classes+for+long-range+assessment+algorithms&rft.au=Swearingen%2C+Michelle%3BWhite%2C+Michael&rft.aulast=Swearingen&rft.aufirst=Michelle&rft.date=2009-10-26&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=158th+Meeting+of+The+Acoustical+Society+of+America&rft.issn=&rft_id=info:doi/ L2 - http://asa.aip.org/sanantonio/program.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Quantitative Evaluation of Structural Damage in Lightweight Armor Materials via XCT T2 - 2009 Materials Science and Technology Conference and Exposition (MS&T 2009) AN - 42583468; 5481782 JF - 2009 Materials Science and Technology Conference and Exposition (MS&T 2009) AU - Green, William AU - Cho, K AU - Montgomery, J Y1 - 2009/10/25/ PY - 2009 DA - 2009 Oct 25 KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42583468?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Materials+Science+and+Technology+Conference+and+Exposition+%28MS%26T+2009%29&rft.atitle=Quantitative+Evaluation+of+Structural+Damage+in+Lightweight+Armor+Materials+via+XCT&rft.au=Green%2C+William%3BCho%2C+K%3BMontgomery%2C+J&rft.aulast=Green&rft.aufirst=William&rft.date=2009-10-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Materials+Science+and+Technology+Conference+and+Exposition+%28MS%26T+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.programmaster.org/PM/PM.nsf/SessionSheetView?OpenForm&Paren tUNID=460830349F34625F8525746B006198F0 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Ferroelectric Thin Film Capacitors to Enable a Miniaturized Smart L-Band Antenna T2 - 2009 Materials Science and Technology Conference and Exposition (MS&T 2009) AN - 42575110; 5480533 JF - 2009 Materials Science and Technology Conference and Exposition (MS&T 2009) AU - Cole, Melanie AU - Romanofsky, Robert AU - Ngo, Eric AU - Toonen, Ryan AU - Ivill, Matthew AU - Hirsch, S G AU - Hubbard, Clifford AU - Keuls, Fred Y1 - 2009/10/25/ PY - 2009 DA - 2009 Oct 25 KW - Antennae KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42575110?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Materials+Science+and+Technology+Conference+and+Exposition+%28MS%26T+2009%29&rft.atitle=Ferroelectric+Thin+Film+Capacitors+to+Enable+a+Miniaturized+Smart+L-Band+Antenna&rft.au=Cole%2C+Melanie%3BRomanofsky%2C+Robert%3BNgo%2C+Eric%3BToonen%2C+Ryan%3BIvill%2C+Matthew%3BHirsch%2C+S+G%3BHubbard%2C+Clifford%3BKeuls%2C+Fred&rft.aulast=Cole&rft.aufirst=Melanie&rft.date=2009-10-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Materials+Science+and+Technology+Conference+and+Exposition+%28MS%26T+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.programmaster.org/PM/PM.nsf/SessionSheetView?OpenForm&Paren tUNID=460830349F34625F8525746B006198F0 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Diffusion Bonding Conditions for Stable and Crack Free Joining of Silicon Carbide T2 - 2009 Materials Science and Technology Conference and Exposition (MS&T 2009) AN - 42571933; 5481158 JF - 2009 Materials Science and Technology Conference and Exposition (MS&T 2009) AU - Halbig, Michael AU - Singh, Mrityunjay Y1 - 2009/10/25/ PY - 2009 DA - 2009 Oct 25 KW - Silicon KW - Diffusion KW - Silicon carbide KW - Adhesion KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42571933?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Materials+Science+and+Technology+Conference+and+Exposition+%28MS%26T+2009%29&rft.atitle=Diffusion+Bonding+Conditions+for+Stable+and+Crack+Free+Joining+of+Silicon+Carbide&rft.au=Halbig%2C+Michael%3BSingh%2C+Mrityunjay&rft.aulast=Halbig&rft.aufirst=Michael&rft.date=2009-10-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Materials+Science+and+Technology+Conference+and+Exposition+%28MS%26T+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.programmaster.org/PM/PM.nsf/SessionSheetView?OpenForm&Paren tUNID=460830349F34625F8525746B006198F0 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Sensor Modeling for the Virtual Autonomous Navigation Environment T2 - 8th Annual IEEE Conference on Sensors (IEEE SENSORS 2009) AN - 42522320; 5451845 JF - 8th Annual IEEE Conference on Sensors (IEEE SENSORS 2009) AU - Goodin, C AU - Carrillo, A AU - Kala, R AU - Liu, L Y Y1 - 2009/10/25/ PY - 2009 DA - 2009 Oct 25 KW - Navigation KW - Sensors KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42522320?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=8th+Annual+IEEE+Conference+on+Sensors+%28IEEE+SENSORS+2009%29&rft.atitle=Sensor+Modeling+for+the+Virtual+Autonomous+Navigation+Environment&rft.au=Goodin%2C+C%3BCarrillo%2C+A%3BKala%2C+R%3BLiu%2C+L+Y&rft.aulast=Goodin&rft.aufirst=C&rft.date=2009-10-25&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=8th+Annual+IEEE+Conference+on+Sensors+%28IEEE+SENSORS+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://ieee-sensors2009.org/program/Sensors2009_FinalProgram.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Astride the Military Cultural Divide: Russia and the Seven Years' War T2 - 2009 Conference on Contest for Continents: The Seven Years' War in Global Perspective AN - 42390383; 5386200 JF - 2009 Conference on Contest for Continents: The Seven Years' War in Global Perspective AU - Menning, Bruce Y1 - 2009/10/22/ PY - 2009 DA - 2009 Oct 22 KW - Russia KW - Culture KW - Military KW - War KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42390383?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Conference+on+Contest+for+Continents%3A+The+Seven+Years%27+War+in+Global+Perspective&rft.atitle=Astride+the+Military+Cultural+Divide%3A+Russia+and+the+Seven+Years%27+War&rft.au=Menning%2C+Bruce&rft.aulast=Menning&rft.aufirst=Bruce&rft.date=2009-10-22&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Conference+on+Contest+for+Continents%3A+The+Seven+Years%27+War+in+Global+Perspective&rft.issn=&rft_id=info:doi/ L2 - http://oieahc.wm.edu/conferences/contest/saturday.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Characterizing the OB/OD Ground at Hingham Annex Using a Different Approach to Multi-Increment Sampling T2 - The 25th Annual International Conference on Soils, Sediments and Water AN - 42399379; 5388914 JF - The 25th Annual International Conference on Soils, Sediments and Water AU - Koenig, Mark AU - Chrigwin, Brad AU - Madison, Jim AU - Hewitt, Alan Y1 - 2009/10/19/ PY - 2009 DA - 2009 Oct 19 KW - Sampling KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42399379?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=The+25th+Annual+International+Conference+on+Soils%2C+Sediments+and+Water&rft.atitle=Characterizing+the+OB%2FOD+Ground+at+Hingham+Annex+Using+a+Different+Approach+to+Multi-Increment+Sampling&rft.au=Koenig%2C+Mark%3BChrigwin%2C+Brad%3BMadison%2C+Jim%3BHewitt%2C+Alan&rft.aulast=Koenig&rft.aufirst=Mark&rft.date=2009-10-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=The+25th+Annual+International+Conference+on+Soils%2C+Sediments+and+Water&rft.issn=&rft_id=info:doi/ L2 - http://www.umasssoils.com/program2009.htm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Evaluation of Treatment Approaches to Reduce Ejecta from Projectile Impact on Sand Catchboxes T2 - The 25th Annual International Conference on Soils, Sediments and Water AN - 42393971; 5388861 JF - The 25th Annual International Conference on Soils, Sediments and Water AU - Medina, Victor AU - Waisner, Scott AU - Tom, Joe AU - Read, Dick Y1 - 2009/10/19/ PY - 2009 DA - 2009 Oct 19 KW - Sand KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42393971?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=The+25th+Annual+International+Conference+on+Soils%2C+Sediments+and+Water&rft.atitle=Evaluation+of+Treatment+Approaches+to+Reduce+Ejecta+from+Projectile+Impact+on+Sand+Catchboxes&rft.au=Medina%2C+Victor%3BWaisner%2C+Scott%3BTom%2C+Joe%3BRead%2C+Dick&rft.aulast=Medina&rft.aufirst=Victor&rft.date=2009-10-19&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=The+25th+Annual+International+Conference+on+Soils%2C+Sediments+and+Water&rft.issn=&rft_id=info:doi/ L2 - http://www.umasssoils.com/program2009.htm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Utilization of Lidar Derived Dems in Assessing Geologic Hazards near Earthen Dams in California, Usa T2 - 2009 Annual Meeting of the Geology Society of America AN - 42136792; 5548971 JF - 2009 Annual Meeting of the Geology Society of America AU - Hunter, Lewis AU - Rose, Ronn AU - Kelson, Keith Y1 - 2009/10/18/ PY - 2009 DA - 2009 Oct 18 KW - USA, California KW - Dams KW - Geology KW - Lidar KW - Hazards KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42136792?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Annual+Meeting+of+the+Geology+Society+of+America&rft.atitle=Utilization+of+Lidar+Derived+Dems+in+Assessing+Geologic+Hazards+near+Earthen+Dams+in+California%2C+Usa&rft.au=Hunter%2C+Lewis%3BRose%2C+Ronn%3BKelson%2C+Keith&rft.aulast=Hunter&rft.aufirst=Lewis&rft.date=2009-10-18&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Annual+Meeting+of+the+Geology+Society+of+America&rft.issn=&rft_id=info:doi/ L2 - http://gsa.confex.com/gsa/2009AM/finalprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Channel Evolution of the Trinity River, Dallas County Texas T2 - 2009 Annual Meeting of the Geology Society of America AN - 42135186; 5550051 JF - 2009 Annual Meeting of the Geology Society of America AU - Manning, Ashley AU - Harrelson, Danny AU - Pearson, Monte Y1 - 2009/10/18/ PY - 2009 DA - 2009 Oct 18 KW - USA, Texas KW - USA, Texas, Dallas KW - USA, Texas, Trinity R. KW - Channels KW - Rivers KW - Evolution KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42135186?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Annual+Meeting+of+the+Geology+Society+of+America&rft.atitle=Channel+Evolution+of+the+Trinity+River%2C+Dallas+County+Texas&rft.au=Manning%2C+Ashley%3BHarrelson%2C+Danny%3BPearson%2C+Monte&rft.aulast=Manning&rft.aufirst=Ashley&rft.date=2009-10-18&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Annual+Meeting+of+the+Geology+Society+of+America&rft.issn=&rft_id=info:doi/ L2 - http://gsa.confex.com/gsa/2009AM/finalprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Mineral Composition and Phenocryst Zoning in Primitive Absarokite at Pepper Mountain, Boring Volcanic Field (Bvf), Oregon T2 - 2009 Annual Meeting of the Geology Society of America AN - 42131429; 5548293 JF - 2009 Annual Meeting of the Geology Society of America AU - Jones, Adam AU - Streck, Martin AU - Conrey, Richard Y1 - 2009/10/18/ PY - 2009 DA - 2009 Oct 18 KW - Zoning KW - Volcanoes KW - Mineral composition KW - Mountains KW - Minerals KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42131429?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Annual+Meeting+of+the+Geology+Society+of+America&rft.atitle=Mineral+Composition+and+Phenocryst+Zoning+in+Primitive+Absarokite+at+Pepper+Mountain%2C+Boring+Volcanic+Field+%28Bvf%29%2C+Oregon&rft.au=Jones%2C+Adam%3BStreck%2C+Martin%3BConrey%2C+Richard&rft.aulast=Jones&rft.aufirst=Adam&rft.date=2009-10-18&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Annual+Meeting+of+the+Geology+Society+of+America&rft.issn=&rft_id=info:doi/ L2 - http://gsa.confex.com/gsa/2009AM/finalprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Soil Disturbance and Property Changes T2 - 2009 Annual Meeting of the Geology Society of America AN - 42130167; 5547038 JF - 2009 Annual Meeting of the Geology Society of America AU - Roig-Silva, Carla AU - Berney, Ernest IV AU - Robert, Stephanie Y1 - 2009/10/18/ PY - 2009 DA - 2009 Oct 18 KW - Soil KW - Disturbance KW - Ecosystem disturbance KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42130167?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Annual+Meeting+of+the+Geology+Society+of+America&rft.atitle=Soil+Disturbance+and+Property+Changes&rft.au=Roig-Silva%2C+Carla%3BBerney%2C+Ernest+IV%3BRobert%2C+Stephanie&rft.aulast=Roig-Silva&rft.aufirst=Carla&rft.date=2009-10-18&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Annual+Meeting+of+the+Geology+Society+of+America&rft.issn=&rft_id=info:doi/ L2 - http://gsa.confex.com/gsa/2009AM/finalprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Provenance Determination of California Obsidian Sources by Laser-Induced Breakdown Spectroscopy T2 - 2009 Annual Meeting of the Geology Society of America AN - 42129004; 5549662 JF - 2009 Annual Meeting of the Geology Society of America AU - Harmon, Russell AU - Gottfried, Jennifer AU - Remus, Jeremiah AU - Baron, Dirk AU - Draucker, Anne AU - Yohe, Robert Y1 - 2009/10/18/ PY - 2009 DA - 2009 Oct 18 KW - USA, California KW - Spectroscopy KW - Provenance KW - Obsidian KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42129004?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Annual+Meeting+of+the+Geology+Society+of+America&rft.atitle=Provenance+Determination+of+California+Obsidian+Sources+by+Laser-Induced+Breakdown+Spectroscopy&rft.au=Harmon%2C+Russell%3BGottfried%2C+Jennifer%3BRemus%2C+Jeremiah%3BBaron%2C+Dirk%3BDraucker%2C+Anne%3BYohe%2C+Robert&rft.aulast=Harmon&rft.aufirst=Russell&rft.date=2009-10-18&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Annual+Meeting+of+the+Geology+Society+of+America&rft.issn=&rft_id=info:doi/ L2 - http://gsa.confex.com/gsa/2009AM/finalprogram/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Antagonists for specific muscarinic receptor subtypes microinjected into the basolateral amygdala protect against soman-induced seizures T2 - 39th Annual meeting of the Society for Neuroscience AN - 42190886; 5579415 JF - 39th Annual meeting of the Society for Neuroscience AU - Skovira, J AU - Chandler, J AU - Van Shura, K AU - Mcdonough, J AU - Shih, T Y1 - 2009/10/17/ PY - 2009 DA - 2009 Oct 17 KW - Amygdala KW - Seizures KW - Acetylcholine receptors (muscarinic) KW - Antagonists KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42190886?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=39th+Annual+meeting+of+the+Society+for+Neuroscience&rft.atitle=Antagonists+for+specific+muscarinic+receptor+subtypes+microinjected+into+the+basolateral+amygdala+protect+against+soman-induced+seizures&rft.au=Skovira%2C+J%3BChandler%2C+J%3BVan+Shura%2C+K%3BMcdonough%2C+J%3BShih%2C+T&rft.aulast=Skovira&rft.aufirst=J&rft.date=2009-10-17&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=39th+Annual+meeting+of+the+Society+for+Neuroscience&rft.issn=&rft_id=info:doi/ L2 - http://www.sfn.org/am2009/index.aspx?pagename=final_program LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Connecting constant and variable coefficient differential equations T2 - 2009 Fall Central Section Meeting Of the American Mathematical Society AN - 42496590; 5442974 JF - 2009 Fall Central Section Meeting Of the American Mathematical Society AU - Wilmer, Archie Y1 - 2009/10/16/ PY - 2009 DA - 2009 Oct 16 KW - Mathematical models KW - Differential equations KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42496590?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Fall+Central+Section+Meeting+Of+the+American+Mathematical+Society&rft.atitle=Connecting+constant+and+variable+coefficient+differential+equations&rft.au=Wilmer%2C+Archie&rft.aulast=Wilmer&rft.aufirst=Archie&rft.date=2009-10-16&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Fall+Central+Section+Meeting+Of+the+American+Mathematical+Society&rft.issn=&rft_id=info:doi/ L2 - http://www.ams.org/amsmtgs/2164_progfull.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - The biological activity of ubiquitinated BoNT/B light chain in vitro and in human SHSY-5Y neuronal cells. AN - 734066558; 19681043 AB - BoNT/B light chain is a zinc-dependent endopeptidase. After entering its target, the neuronal cell, BoNT/B is responsible for synaptobrevin-2 (VAMP-2) cleavage. This results in reduced neurotransmitter (acetylcholine) release from synaptic vesicles, yielding muscular paralysis. Since the toxin persists in neuronal cells for an extended period, regeneration of VAMP-2 is prevented. We evaluated therapeutic targets to overcome botulinum persistence because early removal would rescue the neuronal cell. The ubiquitination/proteasome cellular pathway is responsible for removing "old" or undesirable proteins. Therefore, we assessed ubiquitination of BoNT/B light chain in vitro, and characterized the effects of ubiquitination modulating drugs, PMA (phorbol 12-myristate 13-acetate) and expoxomicin, on ubiquitination of BoNT/B light chain in neuronal cells. Both drugs altered BoNT/B light chain ubiquitination. Ubiquitination in vitro and in cells decreased the biological activity of BoNT/B light chain. These results further elucidate BoNT protein degradation pathways in intoxicated neuronal cells and mechanisms to enhance toxin removal. (c) 2009 Wiley-Liss, Inc. JF - Journal of cellular biochemistry AU - Shi, Xuerong AU - Curran, Jennifer E AU - Liao, Zhilin AU - Gordon, Richard K AD - Department of Regulated Laboratories, Division of Regulated Activities, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, Maryland 20910-7500, USA. xuerong.shi@amedd.army.mil Y1 - 2009/10/15/ PY - 2009 DA - 2009 Oct 15 SP - 660 EP - 667 VL - 108 IS - 3 KW - Ubiquitinated Proteins KW - 0 KW - Vesicle-Associated Membrane Protein 2 KW - rimabotulinumtoxinB KW - 0Y70779M1F KW - Botulinum Toxins KW - EC 3.4.24.69 KW - Botulinum Toxins, Type A KW - Tetradecanoylphorbol Acetate KW - NI40JAQ945 KW - Index Medicus KW - Blotting, Western KW - Ubiquitination -- drug effects KW - Humans KW - Fluorescence Resonance Energy Transfer KW - Tetradecanoylphorbol Acetate -- pharmacology KW - Cell Line, Tumor KW - Time Factors KW - Vesicle-Associated Membrane Protein 2 -- metabolism KW - Neurons -- metabolism KW - Ubiquitinated Proteins -- metabolism KW - Neurons -- drug effects KW - Botulinum Toxins -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/734066558?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+cellular+biochemistry&rft.atitle=The+biological+activity+of+ubiquitinated+BoNT%2FB+light+chain+in+vitro+and+in+human+SHSY-5Y+neuronal+cells.&rft.au=Shi%2C+Xuerong%3BCurran%2C+Jennifer+E%3BLiao%2C+Zhilin%3BGordon%2C+Richard+K&rft.aulast=Shi&rft.aufirst=Xuerong&rft.date=2009-10-15&rft.volume=108&rft.issue=3&rft.spage=660&rft.isbn=&rft.btitle=&rft.title=Journal+of+cellular+biochemistry&rft.issn=1097-4644&rft_id=info:doi/10.1002%2Fjcb.22300 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-11-24 N1 - Date created - 2009-09-29 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1002/jcb.22300 ER - TY - JOUR T1 - Galantamine is a novel post-exposure therapeutic against lethal VX challenge. AN - 67674346; 19647007 AB - The ability of galantamine hydrobromide (GAL HBr) treatment to antagonize O-ethyl-S-(2-diisopropylaminoethyl) methylphosphonothiolate (VX)-induced lethality, impairment of muscle tension, and electroencephalographic (EEG) changes was assessed in guinea pigs. Guinea pigs were challenged with 16.8 microg/kg VX (2LD50). One min after challenge, animals were administered 0.5 mg/kg atropine sulfate (ATR) and 25 mg/kg pyridine-2-aldoxime methochloride (2-PAM). In addition, guinea pigs were given 0, 1, 2, 4, 8 or 10 mg/kg GAL as a post-exposure treatment immediately prior to ATR and 2-PAM. Animals were either monitored for 24-h survival, scheduled for electroencephalography (EEG) recording, or euthanized 60 min later for measurement of indirectly-elicited muscle tension in the hemidiaphragm. Post-exposure GAL therapy produced a dose-dependent increase in survival from lethal VX challenge. Optimal clinical benefits were observed in the presence of 10 mg/kg GAL, which led to 100% survival of VX-challenged guinea pigs. Based on muscle physiology studies, GAL post-exposure treatment protected the guinea pig diaphragm, the major effector muscle of respiration, from fatigue, tetanic fade, and muscular paralysis. Protection against the paralyzing effects of VX was dose-dependent. In EEG studies, GAL did not alter seizure onset for all doses tested. At the highest dose tested (10 mg/kg), GAL decreased seizure duration when administered as a post-exposure treatment 1 min after VX. GAL also reduced the high correlation associated between seizure activity and lethality after 2LD50 VX challenge. GAL may have additional benefits both centrally and peripherally that are unrelated to its established mechanism as a reversible acetylcholinesterase inhibitor (AChEI). JF - Toxicology and applied pharmacology AU - Hilmas, Corey J AU - Poole, Melissa J AU - Finneran, Kathryn AU - Clark, Matthew G AU - Williams, Patrick T AD - Neurobehavioral Toxicology Branch, Analytical Toxicology Division, U.S. Army Medical Research Institute of Chemical Defense, 3100 Ricketts Point Road, Aberdeen Proving Ground, MD 21010, USA. corey.john.hilmas@us.army.mil Y1 - 2009/10/15/ PY - 2009 DA - 2009 Oct 15 SP - 166 EP - 173 VL - 240 IS - 2 KW - Antidotes KW - 0 KW - Cholinesterase Inhibitors KW - Cholinesterase Reactivators KW - Organothiophosphorus Compounds KW - Pralidoxime Compounds KW - Galantamine KW - 0D3Q044KCA KW - Atropine KW - 7C0697DR9I KW - VX KW - 9A4381183B KW - Acetylcholinesterase KW - EC 3.1.1.7 KW - pralidoxime KW - P7MU9UTP52 KW - Index Medicus KW - Erythrocytes -- drug effects KW - Animals KW - Diaphragm -- innervation KW - Diaphragm -- drug effects KW - Guinea Pigs KW - Electroencephalography KW - Disease Models, Animal KW - Pralidoxime Compounds -- pharmacology KW - Erythrocytes -- enzymology KW - Cholinesterase Reactivators -- pharmacology KW - Phrenic Nerve -- drug effects KW - Muscle Fatigue -- drug effects KW - Atropine -- pharmacology KW - Time Factors KW - Phrenic Nerve -- physiopathology KW - Male KW - Seizures -- chemically induced KW - Dose-Response Relationship, Drug KW - Acetylcholinesterase -- blood KW - Seizures -- prevention & control KW - Paralysis -- prevention & control KW - Drug Therapy, Combination KW - Muscle Tonus -- drug effects KW - Paralysis -- chemically induced KW - Cholinesterase Inhibitors -- pharmacology KW - Neurotoxicity Syndromes -- prevention & control KW - Neurotoxicity Syndromes -- etiology KW - Galantamine -- pharmacology KW - Neurotoxicity Syndromes -- physiopathology KW - Antidotes -- pharmacology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67674346?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+applied+pharmacology&rft.atitle=Galantamine+is+a+novel+post-exposure+therapeutic+against+lethal+VX+challenge.&rft.au=Hilmas%2C+Corey+J%3BPoole%2C+Melissa+J%3BFinneran%2C+Kathryn%3BClark%2C+Matthew+G%3BWilliams%2C+Patrick+T&rft.aulast=Hilmas&rft.aufirst=Corey&rft.date=2009-10-15&rft.volume=240&rft.issue=2&rft.spage=166&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+applied+pharmacology&rft.issn=1096-0333&rft_id=info:doi/10.1016%2Fj.taap.2009.07.029 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-10-08 N1 - Date created - 2009-09-28 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.taap.2009.07.029 ER - TY - CPAPER T1 - Edmund Burke's Critique of British Imperialism Prior to Hastings' Impeachment T2 - 2009 Annual Meeting of the Pacific Northwest Political Science Association AN - 42451663; 5420539 JF - 2009 Annual Meeting of the Pacific Northwest Political Science Association AU - Mitchell, Benjamin Y1 - 2009/10/15/ PY - 2009 DA - 2009 Oct 15 KW - British Isles, England, Kent, Hastings KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42451663?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Annual+Meeting+of+the+Pacific+Northwest+Political+Science+Association&rft.atitle=Edmund+Burke%27s+Critique+of+British+Imperialism+Prior+to+Hastings%27+Impeachment&rft.au=Mitchell%2C+Benjamin&rft.aulast=Mitchell&rft.aufirst=Benjamin&rft.date=2009-10-15&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Annual+Meeting+of+the+Pacific+Northwest+Political+Science+Association&rft.issn=&rft_id=info:doi/ L2 - http://legacy.lclark.edu/~pnwpsa/2009/index.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Sensitivity of hurricane surge to morphological parameters of coastal wetlands AN - 1270040181; 2013-011248 AB - Given the history and future risk of storm surge in the United States, functional storm protection techniques are needed to protect vital sectors of the economy and coastal communities. It is widely hypothesized that coastal wetlands offer protection from storm surge and wave action, though the extent of this protection is unknown due to the complexities of flow through vegetation. Here we present the sensitivity of storm-surge numerical modeling results to various coastal wetlands characteristics. An idealized grid domain and 400-km (super 2) marsh feature were used to evaluate the effects of marsh characteristics on hurricane surge, including the effects of bottom friction, elevation, and continuity (the ratio of healthy marsh to open water area within the total wetland area). Through coupled hydrodynamic and wave model simulations, it is confirmed that increased bottom friction reduces storm-surge levels for most storms. However, increases in depth associated with marsh elevation loss generally results in a reduction of surge. As marsh continuity is decreased, coastal surge increases as a result of enhanced surge conveyance into and out of the marsh. Storm surge is parameterized in terms of marsh morphology, namely marsh elevation, frictional characteristics, and degree of segmentation, which will assist in the justification for and optimization of marsh restoration in terms of storm protection. Abstract Copyright (2009) Elsevier, B.V. JF - Estuarine, Coastal and Shelf Science AU - Loder, N M AU - Irish, J L AU - Cialone, M A AU - Wamsley, T V Y1 - 2009/10/10/ PY - 2009 DA - 2009 Oct 10 SP - 625 EP - 636 PB - Elsevier, London VL - 84 IS - 4 SN - 0272-7714, 0272-7714 KW - numerical models KW - geologic hazards KW - marshes KW - elevation KW - friction KW - cyclones KW - Gulf of Mexico KW - finite element analysis KW - mires KW - wetlands KW - digital simulation KW - natural hazards KW - coastal environment KW - storms KW - storm surges KW - North Atlantic KW - hurricanes KW - Atlantic Ocean KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1270040181?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Estuarine%2C+Coastal+and+Shelf+Science&rft.atitle=Sensitivity+of+hurricane+surge+to+morphological+parameters+of+coastal+wetlands&rft.au=Loder%2C+N+M%3BIrish%2C+J+L%3BCialone%2C+M+A%3BWamsley%2C+T+V&rft.aulast=Loder&rft.aufirst=N&rft.date=2009-10-10&rft.volume=84&rft.issue=4&rft.spage=625&rft.isbn=&rft.btitle=&rft.title=Estuarine%2C+Coastal+and+Shelf+Science&rft.issn=02727714&rft_id=info:doi/10.1016%2Fj.ecss.2009.07.036 L2 - http://www.sciencedirect.com/science/journal/02727714 LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2013, American Geosciences Institute. Reference includes data from CAPCAS, Elsevier Scientific Publishers, Amsterdam, Netherlands N1 - Date revised - 2013-01-01 N1 - Number of references - 26 N1 - Document feature - illus. incl. 1 table N1 - Last updated - 2013-01-17 N1 - SubjectsTermNotLitGenreText - Atlantic Ocean; coastal environment; cyclones; digital simulation; elevation; finite element analysis; friction; geologic hazards; Gulf of Mexico; hurricanes; marshes; mires; natural hazards; North Atlantic; numerical models; storm surges; storms; wetlands DO - http://dx.doi.org/10.1016/j.ecss.2009.07.036 ER - TY - CPAPER T1 - The Guard Fit Challenge T2 - 2009 NASPE Conference on Physical Education Teacher Education (NASPE 2009) AN - 42500102; 5445687 JF - 2009 NASPE Conference on Physical Education Teacher Education (NASPE 2009) AU - Farrell, Scott Y1 - 2009/10/07/ PY - 2009 DA - 2009 Oct 07 KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42500102?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+NASPE+Conference+on+Physical+Education+Teacher+Education+%28NASPE+2009%29&rft.atitle=The+Guard+Fit+Challenge&rft.au=Farrell%2C+Scott&rft.aulast=Farrell&rft.aufirst=Scott&rft.date=2009-10-07&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+NASPE+Conference+on+Physical+Education+Teacher+Education+%28NASPE+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.aahperd.org/naspe/professionaldevelopment/conferences/pete/ upload/DetailedProgram.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Sealing a Geologic Repository for Radioactive Waste T2 - 2009 American Institute of Professional Geologists Annual Meeting AN - 42397204; 5389011 JF - 2009 American Institute of Professional Geologists Annual Meeting AU - Wakeley, Lillian Y1 - 2009/10/03/ PY - 2009 DA - 2009 Oct 03 KW - Hazardous wastes KW - Radioactive wastes KW - Geology KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42397204?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+American+Institute+of+Professional+Geologists+Annual+Meeting&rft.atitle=Sealing+a+Geologic+Repository+for+Radioactive+Waste&rft.au=Wakeley%2C+Lillian&rft.aulast=Wakeley&rft.aufirst=Lillian&rft.date=2009-10-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+American+Institute+of+Professional+Geologists+Annual+Meeting&rft.issn=&rft_id=info:doi/ L2 - http://www.aipg.org/2009/Tentative%20Program%20Grand%20Junction.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Physiologically based pharmacokinetic modeling of cyclotrimethylenetrinitramine in male rats AN - 883020930; 15241887 AB - A physiologically based pharmacokinetic (PBPK) model for simulating the kinetics of cyclotrimethylene trinitramine (RDX) in male rats was developed. The model consisted of five compartments interconnected by systemic circulation. The tissue uptake of RDX was described as a perfusion-limited process whereas hepatic clearance and gastrointestinal absorption were described as first-order processes. The physiological parameters for the rat were obtained from the literature whereas the tissue : blood partition coefficients were estimated on the basis of the tissue and blood composition as well as the lipophilicity characteristics of RDX (logP = 0.87). The tissue : blood partition coefficients (brain, 1.4; muscle, 1; fat, 7.55; liver, 1.2) obtained with this algorithmic approach were used without any adjustment, since a focused in vitro study indicated that the relative concentration of RDX in whole blood and plasma is about 1 : 1. An initial estimate of metabolic clearance of RDX (2.2 h-1 kg-1) was obtained by fitting PBPK model simulations to the data on plasma kinetics in rats administered 5.5 mg kg-1 i.v. The rat PBPK model without any further change in parameter values adequately simulated the blood kinetic data for RDX at much lower doses (0.77 and 1.04 mg -1 i.v.), collected in this study. The same model, with the incorporation of a first order oral absorption rate constant (Ka 0.75 h-1), reproduced the blood kinetics of RDX in rats receiving a single gavage dose of 1.53 or 2.02 mg kg-1. Additionally, the model simulated the plasma and blood kinetics of orally administered RDX at a higher dose (100 mg kg-1) or lower doses (0.2 or 1.24 mg kg-1) in male rats. Overall, the rat PBPK model for RDX with its parameters adequately simulates the blood and plasma kinetic data, obtained following i.v. doses ranging from 0.77 to 5.5 mg kg-1 as well as oral doses ranging from 0.2 to 100 mg kg-1. Published in 2009 by John Wiley & Sons, Ltd. JF - Journal of Applied Toxicology AU - Krishnan, Kannan AU - Crouse, Lee C B AU - Bazar, Matthew A AU - Major, Michael A AU - Reddy, Gunda AD - DSEST, Universite de Montreal, Montreal, Quebec, Canada, gunda.reddy@us.army.mil Y1 - 2009/10// PY - 2009 DA - Oct 2009 SP - 629 EP - 637 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 29 IS - 7 SN - 1099-1263, 1099-1263 KW - Environment Abstracts; Toxicology Abstracts KW - Data processing KW - Physiology KW - Oral administration KW - Muscles KW - Brain KW - Simulation KW - Pharmacokinetics KW - Rats KW - Blood KW - Kinetics KW - Absorption KW - Liver KW - X 24300:Methods KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/883020930?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Toxicology&rft.atitle=Physiologically+based+pharmacokinetic+modeling+of+cyclotrimethylenetrinitramine+in+male+rats&rft.au=Krishnan%2C+Kannan%3BCrouse%2C+Lee+C+B%3BBazar%2C+Matthew+A%3BMajor%2C+Michael+A%3BReddy%2C+Gunda&rft.aulast=Krishnan&rft.aufirst=Kannan&rft.date=2009-10-01&rft.volume=29&rft.issue=7&rft.spage=629&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Toxicology&rft.issn=10991263&rft_id=info:doi/10.1002%2Fjat.1455 L2 - http://onlinelibrary.wiley.com/doi/10.1002/jat.1455/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-08-01 N1 - Last updated - 2015-04-09 N1 - SubjectsTermNotLitGenreText - Blood; Data processing; Kinetics; Brain; Muscles; Oral administration; Liver; Pharmacokinetics; Rats; Physiology; Absorption; Simulation DO - http://dx.doi.org/10.1002/jat.1455 ER - TY - JOUR T1 - Channel evolution of the Trinity River, Dallas County Texas AN - 877842250; 2011-058001 AB - A time line for channel evolution of the Dallas County reach of the Trinity River has been constructed. Four distinct channels dating 1890, 1909, 1918 and 1954 have been identified and compared to the river's present location. Modern evolutionary history of the Trinity began in 1908 when it flooded most of Dallas in an event that exceeded all 19 (super th) century records. This flood event had a gage reading of 52.6 feet and resulted in the Trinity River being approximately 2 miles wide. The memory of the 1908 flood spurred the development of the city of Dallas and construction of a levee system along the Trinity River. Construction of this levee system began in 1928 and included moving the confluence of the Elm and West Forks 3.5 miles to the west and construction of a straight channel 15 miles in length and located 0.5 miles west of the original channel. Also in 1928 two large water supply reservoirs were constructed in the headwaters of the Trinity. These reservoirs further altered the river's flow regime by storing water and effectively reducing the flashiness of the River. After another significant flood in 1948, the levee reconstruction efforts included moving the southern Dallas reach of the channel and dredging the channel to increase its width and depth. In the later half of the 20 (super th) century, the continued development of Dallas County caused an increase in urban runoff and thus the river's flashiness. Also during this time, growth of the Great Trinity Forest in the downstream reach of the Trinity significantly reduced conveyance capacity. In conclusion, the modern Trinity River has been unable to evolve naturally due to anthropogenic regime changes made during the 20 (super th) century and is in response, behaving as a geomorphologically young stream. JF - Abstracts with Programs - Geological Society of America AU - Manning, Ashley R AU - Harrelson, Danny W AU - Pearson, Monte L AU - Anonymous Y1 - 2009/10// PY - 2009 DA - October 2009 SP - 623 PB - Geological Society of America (GSA), Boulder, CO VL - 41 IS - 7 SN - 0016-7592, 0016-7592 KW - United States KW - levees KW - Trinity River KW - landform evolution KW - channels KW - Texas KW - geomorphology KW - Dallas County Texas KW - 23:Geomorphology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/877842250?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Abstracts+with+Programs+-+Geological+Society+of+America&rft.atitle=Channel+evolution+of+the+Trinity+River%2C+Dallas+County+Texas&rft.au=Manning%2C+Ashley+R%3BHarrelson%2C+Danny+W%3BPearson%2C+Monte+L%3BAnonymous&rft.aulast=Manning&rft.aufirst=Ashley&rft.date=2009-10-01&rft.volume=41&rft.issue=7&rft.spage=623&rft.isbn=&rft.btitle=&rft.title=Abstracts+with+Programs+-+Geological+Society+of+America&rft.issn=00167592&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Geological Society of America, 2009 annual meeting N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by the Geological Society of America, Boulder, CO, United States N1 - Date revised - 2011-01-01 N1 - PubXState - CO N1 - Last updated - 2012-06-07 N1 - CODEN - GAAPBC N1 - SubjectsTermNotLitGenreText - channels; Dallas County Texas; geomorphology; landform evolution; levees; Texas; Trinity River; United States ER - TY - JOUR T1 - Utilization of lidar derived DEMs in assessing geologic hazards near earthen dams in California, USA AN - 859729876; 2011-032034 AB - The U.S. Army Corps of Engineers, Sacramento District is using LiDAR-derived digital elevation models (DEM) and hillshade maps as integral tools in analyses of geologic and hydrologic hazards. LiDAR imagery is being applied to further define and characterize known active faults, identify and characterize previously unknown faults on regional and local scales, and aid floodplain mapping downstream of Corps structures. Off-the-shelf LiDAR data originally acquired to support hydrologic modeling at Martis Creek Dam (Nevada County) revealed several linear features 2.5 km southeast of the dam that project toward the dam. Additional data now reveal a northwest-trending right-lateral fault zone that extends approximately 35 km and passes within 100 m of the dam's left abutment. LiDAR surveys have also been flown along the Kern Canyon Fault (KCF), which runs beneath the right abutment of the Isabella Auxiliary Dam (Kern County). The fault had previously been believed inactive. However, analysis of the LiDAR data helped target fruitful areas for detailed geomorphic mapping and paleoseismic trenching that have documented Holocene fault rupture. The success of these two surveys in identifying previously unknown faults or in redefining a known fault as active has been critical in demonstrating that LiDAR technology is an important tool for evaluating geologic hazards in dam safety reevaluations. These demonstrations are playing an important role in justifying and planning additional surveys along the western foothills of the Sierra Nevada Mountains. Two such surveys are planned to support seismic hazard studies of Hidden Dam (Madera County) and Success Dam (Tulare County). These data will be used for regional characterization of seismic sources as well as for assessing spillway geologic conditions. Geomorphic structures suggested by 10m USGS DEMs, but beyond the extent of current published maps will be investigated to further evaluate potential seismic hazards to Corps structures. Lower resolution imagery, but consistent with FEMA guidelines, are also being collected downstream of these structures for floodplain mapping. These data form the topographic baseline for modeling flooding events, estimating risks downstream, and for estimating economic benefits of the project. JF - Abstracts with Programs - Geological Society of America AU - Hunter, Lewis E AU - Rose, Ronn S AU - Kelson, Keith I AU - Anonymous Y1 - 2009/10// PY - 2009 DA - October 2009 SP - 432 PB - Geological Society of America (GSA), Boulder, CO VL - 41 IS - 7 SN - 0016-7592, 0016-7592 KW - United States KW - Tulare County California KW - laser methods KW - geologic hazards KW - Hidden Dam KW - digital terrain models KW - Success Dam KW - evaluation KW - Nevada County California KW - California KW - utilization KW - Martis Creek Dam KW - earth dams KW - Madera County California KW - dams KW - floods KW - gravity dams KW - radar methods KW - detection KW - lidar methods KW - natural hazards KW - risk assessment KW - earthquakes KW - remote sensing KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/859729876?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Abstracts+with+Programs+-+Geological+Society+of+America&rft.atitle=Utilization+of+lidar+derived+DEMs+in+assessing+geologic+hazards+near+earthen+dams+in+California%2C+USA&rft.au=Hunter%2C+Lewis+E%3BRose%2C+Ronn+S%3BKelson%2C+Keith+I%3BAnonymous&rft.aulast=Hunter&rft.aufirst=Lewis&rft.date=2009-10-01&rft.volume=41&rft.issue=7&rft.spage=432&rft.isbn=&rft.btitle=&rft.title=Abstracts+with+Programs+-+Geological+Society+of+America&rft.issn=00167592&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Geological Society of America, 2009 annual meeting N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by the Geological Society of America, Boulder, CO, United States N1 - Date revised - 2011-01-01 N1 - PubXState - CO N1 - Last updated - 2012-06-07 N1 - CODEN - GAAPBC N1 - SubjectsTermNotLitGenreText - California; dams; detection; digital terrain models; earth dams; earthquakes; evaluation; floods; geologic hazards; gravity dams; Hidden Dam; laser methods; lidar methods; Madera County California; Martis Creek Dam; natural hazards; Nevada County California; radar methods; remote sensing; risk assessment; Success Dam; Tulare County California; United States; utilization ER - TY - JOUR T1 - The Midcontinent Rift, north central USA AN - 859728478; 2011-030593 AB - The Midcontinent Rift System (MRS) of central North America is a Proterozoic flood basalt province formed along a 2000 km continental rift activated by the arrival of a mantle plume approximately 1.1 Ga ago. The MRS province consists largely of mafic igneous and overlying sedimentary rocks with a thickness of at least 30 km in the vicinity of Lake Superior where it is exposed at the surface. Although most surface exposures of igneous rocks occur around Lake Superior the rift extends beneath Phanerozoic sediments SW from Lake Superior through Iowa into Nebraska and Kansas. Shorter arms extend SE into Michigan and N into Ontario. The thick volcanic section is intruded by numerous small dikes and sills as well as the large Duluth layered complex. Exposures of the intrusions are best in and near Duluth and along the north shore of Minnesota with Lake Superior. The geochemistry of mafic lavas, dikes, and sills is governed largely by the interaction of plume melt with adjacent mantle. JF - Abstracts with Programs - Geological Society of America AU - Seifert, Karl E AU - Musilek, Jennifer A AU - Anonymous Y1 - 2009/10// PY - 2009 DA - October 2009 SP - 371 PB - Geological Society of America (GSA), Boulder, CO VL - 41 IS - 7 SN - 0016-7592, 0016-7592 KW - United States KW - North America KW - flood basalts KW - volcanic rocks KW - upper Precambrian KW - Precambrian KW - igneous rocks KW - mantle KW - Proterozoic KW - Iowa KW - Ontario KW - north-central United States KW - Keweenawan Rift KW - Kansas KW - Canada KW - basalts KW - thickness KW - Michigan KW - Eastern Canada KW - Nebraska KW - crust KW - Midwest KW - 18:Solid-earth geophysics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/859728478?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Abstracts+with+Programs+-+Geological+Society+of+America&rft.atitle=The+Midcontinent+Rift%2C+north+central+USA&rft.au=Seifert%2C+Karl+E%3BMusilek%2C+Jennifer+A%3BAnonymous&rft.aulast=Seifert&rft.aufirst=Karl&rft.date=2009-10-01&rft.volume=41&rft.issue=7&rft.spage=371&rft.isbn=&rft.btitle=&rft.title=Abstracts+with+Programs+-+Geological+Society+of+America&rft.issn=00167592&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Geological Society of America, 2009 annual meeting N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by the Geological Society of America, Boulder, CO, United States N1 - Date revised - 2011-01-01 N1 - PubXState - CO N1 - Last updated - 2012-06-07 N1 - CODEN - GAAPBC N1 - SubjectsTermNotLitGenreText - basalts; Canada; crust; Eastern Canada; flood basalts; igneous rocks; Iowa; Kansas; Keweenawan Rift; mantle; Michigan; Midwest; Nebraska; North America; north-central United States; Ontario; Precambrian; Proterozoic; thickness; United States; upper Precambrian; volcanic rocks ER - TY - JOUR T1 - Climate response of yellow-cedar on Excursion Ridge, Glacier Bay, Alaska; a preliminary analysis of pre- and post Little Ice Age climate signals AN - 807618885; 2010-099445 AB - The Alaska yellow-cedar, Callitropsis nootkatensis (D. Don) Orsted, is in the midst of a century-long decline, coinciding with the end of the Little Ice Age, circa A.D. 1880. This decline appears to have not yet affected yellow-cedar stands around Glacier Bay, southeast Alaska. The longevity of the species is conducive to the creation of long-term chronologies of a half millennium or more. A preliminary ring-width chronology of thirty-four cores from seventeen yellow-cedar that spans 439 years, from 1538-2006 was created, showing a strong common signal with a 0.518 series intercorrelation. The chronology was then standardized using a conservative 150-year cubic smoothing spline and the standard chronology was then compared to various local climate data. Of particular interest were two distinct response trends when compared with the extensive Sitka Magnetic Observatory records. These records are among the longest continuous recorded climate record in North America, starting in 1828 and ending in 1989. In the Russian, pre-LIA data, the Cedar responded positively to warmer winter temperatures. Comparison with the post-LIA indicated the trees responded negatively to warmer spring and December. Warmer winter temperatures in the Gulf of Alaska correlate strongly with higher snowfall in the coastal areas, and available snowpack is vital to the survival of shallow-rooted trees such as the yellow-cedar. Decreases in winter snowpack and frost damage to roots has been implicated in the decline of yellow cedar in Southeast Alaska. This correlation between winter temperatures, precipitation and the relative effect on cedar survival merits further investigation. Ongoing work includes the development of a second cedar site from the Glacier Bay region as well as the expansion of the current site's chronology. These chronologies will continue to be assessed for indications of cedar decline and potential for climate reconstruction. JF - Abstracts with Programs - Geological Society of America AU - Mennett, Colin AU - Wiles, Gregory C AU - Lawson, Daniel AU - Anonymous Y1 - 2009/10// PY - 2009 DA - October 2009 SP - 273 PB - Geological Society of America (GSA), Boulder, CO VL - 41 IS - 7 SN - 0016-7592, 0016-7592 KW - United States KW - Plantae KW - Pinales KW - Quaternary KW - Callitropsis nootkatensis KW - Pinophyta KW - paleoclimatology KW - Holocene KW - Cenozoic KW - Excursion Ridge KW - Neoglacial KW - Glacier Bay KW - Alaska KW - reconstruction KW - Pinopsida KW - 24:Quaternary geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/807618885?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Abstracts+with+Programs+-+Geological+Society+of+America&rft.atitle=Climate+response+of+yellow-cedar+on+Excursion+Ridge%2C+Glacier+Bay%2C+Alaska%3B+a+preliminary+analysis+of+pre-+and+post+Little+Ice+Age+climate+signals&rft.au=Mennett%2C+Colin%3BWiles%2C+Gregory+C%3BLawson%2C+Daniel%3BAnonymous&rft.aulast=Mennett&rft.aufirst=Colin&rft.date=2009-10-01&rft.volume=41&rft.issue=7&rft.spage=273&rft.isbn=&rft.btitle=&rft.title=Abstracts+with+Programs+-+Geological+Society+of+America&rft.issn=00167592&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Geological Society of America, 2009 annual meeting N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by the Geological Society of America, Boulder, CO, United States N1 - Date revised - 2010-01-01 N1 - PubXState - CO N1 - Last updated - 2012-06-07 N1 - CODEN - GAAPBC N1 - SubjectsTermNotLitGenreText - Alaska; Callitropsis nootkatensis; Cenozoic; Excursion Ridge; Glacier Bay; Holocene; Neoglacial; paleoclimatology; Pinales; Pinophyta; Pinopsida; Plantae; Quaternary; reconstruction; United States ER - TY - JOUR T1 - Soil disturbance and property changes AN - 759303438; 2010-086587 AB - Fieldwork was performed to evaluate changes in soil properties from an undisturbed to a disturbed state at five locations of differing geology using the US Army Rapid Soils Analysis and Rapid Quality Assurance Kits. Tested soil textures ranged from clay in Virginia, sand in Florida, silt in New Mexico and fine to coarse silty-sands in California and Arizona. Soils were tested at the ground surface and at a depth of 35 cm in both the in-situ condition and after being excavated and replaced. Properties measured included mineralogy, soil texture, Unified Soil Classification System (USCS) gradation, apparent soil gradation, moisture content, bulk density and thermal conductivity. Changes in these measured properties differed according to the geologic conditions of the sampled regions and the presence of gypsum and calcium carbonate deposits. Discussed are the magnitude of changes with soil type, correlations between measured properties and the influence of apparent soil gradation. Apparent soil gradation after disturbance differed from the USCS gradation in cases where partial cementation and duricrust development were present and was found to be the key indicator of soil property variability. JF - Abstracts with Programs - Geological Society of America AU - Roig-Silva, Carla AU - Berney, Ernest, IV AU - Robert, Stephanie AU - Anonymous Y1 - 2009/10// PY - 2009 DA - October 2009 SP - 88 EP - 89 PB - Geological Society of America (GSA), Boulder, CO VL - 41 IS - 7 SN - 0016-7592, 0016-7592 KW - United States KW - soils KW - soil mechanics KW - bulk density KW - Virginia KW - thermal conductivity KW - engineering properties KW - textures KW - moisture KW - New Mexico KW - Florida KW - California KW - mineral composition KW - heat flow KW - Arizona KW - soil surveys KW - surveys KW - 30:Engineering geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/759303438?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Abstracts+with+Programs+-+Geological+Society+of+America&rft.atitle=Soil+disturbance+and+property+changes&rft.au=Roig-Silva%2C+Carla%3BBerney%2C+Ernest%2C+IV%3BRobert%2C+Stephanie%3BAnonymous&rft.aulast=Roig-Silva&rft.aufirst=Carla&rft.date=2009-10-01&rft.volume=41&rft.issue=7&rft.spage=88&rft.isbn=&rft.btitle=&rft.title=Abstracts+with+Programs+-+Geological+Society+of+America&rft.issn=00167592&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Geological Society of America, 2009 annual meeting N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by the Geological Society of America, Boulder, CO, United States N1 - Date revised - 2010-01-01 N1 - PubXState - CO N1 - Last updated - 2012-06-07 N1 - CODEN - GAAPBC N1 - SubjectsTermNotLitGenreText - Arizona; bulk density; California; engineering properties; Florida; heat flow; mineral composition; moisture; New Mexico; soil mechanics; soil surveys; soils; surveys; textures; thermal conductivity; United States; Virginia ER - TY - JOUR T1 - A practical bio-engineered approach to remediation of contaminated ground water discharging to a tidal wetland and stream AN - 756292947; 2010-084019 AB - A ground water remediation strategy that combines natural attenuation and enhanced bioremediation is put forth to protect a perennial stream flowing through a tidal wetland. The tidal wetland contains ground water seeps, some of which are contaminated with chlorinated volatile organic compounds (VOCs). Thermal mapping, hydraulic gradient and seepage flux monitoring, together with geochemical analysis and ground water modeling, demonstrate that the seeps are conduits for higher velocity ground water discharges compared to the surrounding wetland sediments. The wetland sediments are shown to reduce VOC contaminant plume concentrations more effectively than the seep areas because of the longer contaminant residence times and persistent methanogenic conditions that promote biodegradation. Multiple, very old VOC sources are located in both the upland and tidal wetland areas producing diffuse (>50 acre) VOC plumes that discharge to the tidal wetland sediments and seeps. 20 years of site investigations have not identified well-defined source areas and the VOC plumes are observed to be relatively stable. Predictive model simulations indicate that the VOC plume will persist for a lengthy timeframe as VOCs will continue to diffuse out of the silt and clay matrix. The management and restoration strategy presented is designed to achieve long-term VOC mass reduction of the contaminant plumes to protect the stream environment. Bio-engineered plume treatment will be focused directly upgradient of the ground water/surface water interface in the most contaminated ground water seeps. Treatment will utilize field tested permeable reactive mat technology constructed of a mixture of sand, peat, zero valent iron, and electron donor with bioaugmentation of native microorganisms (WBC-2). The reactive mats are demonstrated to reduce over 90% of VOC mass prior to ground water discharging to the stream. Recent re-testing indicated that VOC degradation and methanogenic conditions are sustained in the reactive mat for over 3 years. Focusing bio-enhanced treatment of the VOC plumes at the seep areas provides the most effective and practical restoration strategy by providing a long-term protective remedy for an ecologically sensitive tidal stream JF - Abstracts with Programs - Geological Society of America AU - Schneider, William H AU - Lorah, Michelle AU - Majcher, Emily AU - Wrobel, John AU - Serdakowski, Mary AU - Anonymous Y1 - 2009/10// PY - 2009 DA - October 2009 SP - 44 PB - Geological Society of America (GSA), Boulder, CO VL - 41 IS - 7 SN - 0016-7592, 0016-7592 KW - methods KW - contaminant plumes KW - surface water KW - pollution KW - bioremediation KW - reactive mats KW - environmental analysis KW - remediation KW - ground water KW - volatiles KW - organic compounds KW - wetlands KW - volatile organic compounds KW - natural attenuation KW - streams KW - discharge KW - water pollution KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/756292947?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Abstracts+with+Programs+-+Geological+Society+of+America&rft.atitle=A+practical+bio-engineered+approach+to+remediation+of+contaminated+ground+water+discharging+to+a+tidal+wetland+and+stream&rft.au=Schneider%2C+William+H%3BLorah%2C+Michelle%3BMajcher%2C+Emily%3BWrobel%2C+John%3BSerdakowski%2C+Mary%3BAnonymous&rft.aulast=Schneider&rft.aufirst=William&rft.date=2009-10-01&rft.volume=41&rft.issue=7&rft.spage=44&rft.isbn=&rft.btitle=&rft.title=Abstracts+with+Programs+-+Geological+Society+of+America&rft.issn=00167592&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Geological Society of America, 2009 annual meeting N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by the Geological Society of America, Boulder, CO, United States N1 - Date revised - 2010-01-01 N1 - PubXState - CO N1 - Last updated - 2012-06-07 N1 - CODEN - GAAPBC N1 - SubjectsTermNotLitGenreText - bioremediation; contaminant plumes; discharge; environmental analysis; ground water; methods; natural attenuation; organic compounds; pollution; reactive mats; remediation; streams; surface water; volatile organic compounds; volatiles; water pollution; wetlands ER - TY - JOUR T1 - Unilateral Hypoglossal Nerve Injury in a Collegiate Wrestler: A Case Report AN - 745902263; 12683224 AB - Objective: To introduce the case of a collegiate wrestler who suffered a traumatic unilateral hypoglossal nerve injury. This case presents the opportunity to discuss the diagnosis and treatment of a 20-year-old man with an injury to his right hypoglossal nerve. Background: Injuries to the hypoglossal nerve (cranial nerve XII) are rare. Most reported cases are the result of malignancy, with traumatic causes less common. In this case, a collegiate wrestler struck his head on the wrestling mat during practice. No loss of consciousness occurred. The wrestler initially demonstrated signs and symptoms of a mild concussion, with dizziness and a headache. These concussion symptoms cleared quickly, but the athlete complained of difficulty swallowing (dysphagia) and demonstrated slurred speech (dysarthria). Also, his tongue deviated toward the right. No other neurologic deficits were observed. Differential Diagnosis: Occipital-cervical junction fracture, syringomyella, malignancy, latrogenic causes, cranial nerve Injury. Treatment: After initial injury recognition, the athletic trainer placed the patient in a cervical collar and transported him to the emergency department. The patient received prednisone, and the emergency medicine physician ordered cervical spine plain radiographs, brain computed tomography, and brain and internal auditory canal magnetic resonance Imaging. The physician consulted a neurologist, who managed the patient conservatively, with rest and no contact activity. The neurologist allowed the patient to participate in wrestling 7 months after injury. Uniqueness: To our knowledge, no other reports of unilateral hypoglossal nerve injury from relatively low-energy trauma (including athletics) exist. Conclusions: Hypoglossal nerve injury should be considered In individuals with head injury who experience dysphagia and dysarthria. Athletes with head injuries require cranial nerve assessments. JF - Journal of Athletic Training AU - Loro, WA AU - Owens, B AD - US Army Medical Department Center and School, PT Branch A.TTN MCCS-HGE-PT. 3161 Scott Road. Suite 1303. Fort Sam Houston, TX 78234-6138, USA, william.loro@us.army.mil Y1 - 2009/10// PY - 2009 DA - Oct 2009 SP - 534 EP - 537 VL - 44 IS - 5 SN - 1062-6050, 1062-6050 KW - CSA Neurosciences Abstracts; Physical Education Index KW - Collars KW - Prednisone KW - swallowing KW - Injuries KW - Intercollegiate sports KW - Magnetic resonance imaging KW - Evaluation KW - Malignancy KW - Consciousness KW - Headache KW - Tongue KW - Ear canal KW - Cranial nerves KW - Wrestling KW - Brain injury KW - concussion KW - Head KW - Fractures KW - Brain KW - Patients KW - Concussion KW - Trauma KW - Dysphagia KW - Hypoglossal nerve KW - speech KW - Differential diagnosis KW - Case reports KW - Computed tomography KW - spine (cervical) KW - Radiography KW - Athletes KW - N3 11001:Behavioral and Cognitive Neuroscience KW - PE 090:Sports Medicine & Exercise Sport Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745902263?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Athletic+Training&rft.atitle=Unilateral+Hypoglossal+Nerve+Injury+in+a+Collegiate+Wrestler%3A+A+Case+Report&rft.au=Loro%2C+WA%3BOwens%2C+B&rft.aulast=Loro&rft.aufirst=WA&rft.date=2009-10-01&rft.volume=44&rft.issue=5&rft.spage=534&rft.isbn=&rft.btitle=&rft.title=Journal+of+Athletic+Training&rft.issn=10626050&rft_id=info:doi/ LA - English DB - Physical Education Index N1 - Date revised - 2010-05-01 N1 - Last updated - 2013-05-31 N1 - SubjectsTermNotLitGenreText - Wrestling; Evaluation; Head; Injuries; Intercollegiate sports; Brain; Concussion; Patients; Athletes; Cranial nerves; Collars; swallowing; Prednisone; Brain injury; concussion; Magnetic resonance imaging; Fractures; Trauma; Dysphagia; speech; Consciousness; Hypoglossal nerve; Malignancy; Differential diagnosis; Case reports; Computed tomography; Headache; spine (cervical); Tongue; Radiography; Ear canal ER - TY - JOUR T1 - Late Quaternary stratigraphy of the upper Ohio-Allegheny River basin; a developing framework for geoarchaeological investigations AN - 742920188; 2010-057046 AB - Site-specific geomorphic and archaeologic investigations throughout the Upper Ohio-Allegheny River basin provide significant insight into the late Quaternary geologic history of the region. This paper presents a selected synthesis of existing data to develop a regional stratigraphic framework for alluvial geoarchaeological investigations in the Upper Ohio-Allegheny River basin. During glacial and deglacial times, glaciated tributaries routed significant volumes of meltwater and sediment southward through the Upper Ohio-Allegheny River and away from the glacial margin. Existing data indicate glaciers retreated from the basin by 13-14 ka. Streams responded to lower water volumes and sediment supply by incision and a transition from braided to meandering planforms. Both the Allegheny and Upper Ohio Rivers are commonly flanked by one to several late Quaternary terraces depending on local geologic and geomorphic conditions. The alluvial landforms hold significant archaeological site potential. Alluvial terraces along meltwater courses within the basin may contain cultural deposits dating back to the Paleoindian Period in surface and shallow subsurface context. Where present, the oldest Holocene terraces have the potential to contain cultural deposits dating back to the early Archaic Period. Younger and lower Holocene terraces, and the active floodplain may contain deposits dating to the middle Archaic and younger depending on specific landform age. Although developed using site-specific data, the stratigraphic framework developed herein should be applicable to meltwater influenced reaches of larger streams in the Upper Ohio-Allegheny River basin, and also provide significant information concerning late Quaternary landscape evolution at the regional scale. JF - Abstracts with Programs - Geological Society of America AU - Grote, Todd AU - Robinson, R AU - Schaney, M AU - Straffin, Eric AU - Myers, A AU - Anonymous Y1 - 2009/10// PY - 2009 DA - October 2009 SP - 204 PB - Geological Society of America (GSA), Boulder, CO VL - 41 IS - 7 SN - 0016-7592, 0016-7592 KW - United States KW - Quaternary KW - Illinois KW - floodplains KW - Allegheny River KW - landform evolution KW - paleoclimatology KW - Holocene KW - exploration KW - Cenozoic KW - archaeological sites KW - upper Quaternary KW - Indiana KW - Ohio River basin KW - fluvial features KW - Kentucky KW - Pennsylvania KW - West Virginia KW - Ohio River KW - Ohio KW - 24:Quaternary geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742920188?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Abstracts+with+Programs+-+Geological+Society+of+America&rft.atitle=Late+Quaternary+stratigraphy+of+the+upper+Ohio-Allegheny+River+basin%3B+a+developing+framework+for+geoarchaeological+investigations&rft.au=Grote%2C+Todd%3BRobinson%2C+R%3BSchaney%2C+M%3BStraffin%2C+Eric%3BMyers%2C+A%3BAnonymous&rft.aulast=Grote&rft.aufirst=Todd&rft.date=2009-10-01&rft.volume=41&rft.issue=7&rft.spage=204&rft.isbn=&rft.btitle=&rft.title=Abstracts+with+Programs+-+Geological+Society+of+America&rft.issn=00167592&rft_id=info:doi/ LA - English DB - GeoRef N1 - Conference title - Geological Society of America, 2009 annual meeting N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data supplied by the Geological Society of America, Boulder, CO, United States N1 - Date revised - 2010-01-01 N1 - PubXState - CO N1 - Last updated - 2012-06-07 N1 - CODEN - GAAPBC N1 - SubjectsTermNotLitGenreText - Allegheny River; archaeological sites; Cenozoic; exploration; floodplains; fluvial features; Holocene; Illinois; Indiana; Kentucky; landform evolution; Ohio; Ohio River; Ohio River basin; paleoclimatology; Pennsylvania; Quaternary; United States; upper Quaternary; West Virginia ER - TY - JOUR T1 - Battlemind Debriefing and Battlemind Training as Early Interventions With Soldiers Returning From Iraq: Randomization by Platoon AN - 742716631; 201008816 AB - Researchers have found that there is an increase in mental health problems as a result of military-related traumatic events, and such problems increase in the months following return from combat. Nevertheless, researchers have not assessed the impact of early intervention efforts with this at-risk population. In the present study, the authors compared different early interventions with 2,297 U.S. soldiers following a year-long deployment to Iraq. Platoons were randomly assigned to standard postdeployment stress education, Battlemind debriefing, and small and large group Battlemind training. Results from a 4-month follow-up with 1,060 participants showed those with high levels of combat exposure who received Battlemind debriefing reported fewer posttraumatic stress symptoms, depression symptoms, and sleep problems than those in stress education. Small group Battlemind training participants with high combat exposure reported fewer posttraumatic stress symptoms and sleep problems than stress education participants. Compared to stress education participants, large group Battlemind training participants with high combat exposure reported fewer posttraumatic stress symptoms and lower levels of stigma and, regardless of combat exposure, reported fewer depression symptoms. Findings demonstrate that brief early interventions have the potential to be effective with at-risk occupational groups. [Copyright American Psychological Association] JF - Journal of Consulting and Clinical Psychology AU - Adler, Amy B AU - Bliese, Paul D AU - McGurk, Dennis AU - Hoge, Charles W AU - Castro, Carl Andrew AD - U.S. Army Medical Research Unit-Europe, Walter Reed Army Institute of Research, Heidelberg, Germany amy.adler@us.army.mil Y1 - 2009/10// PY - 2009 DA - October 2009 SP - 928 EP - 940 PB - American Psychological Association, Washington DC VL - 77 IS - 5 SN - 0022-006X, 0022-006X KW - combat experiences debriefing soldiers postdeployment stigma KW - Symptoms KW - Posttraumatic stress disorder KW - Early intervention programmes KW - Debriefing KW - Stress KW - Iraq KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742716631?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Consulting+and+Clinical+Psychology&rft.atitle=Battlemind+Debriefing+and+Battlemind+Training+as+Early+Interventions+With+Soldiers+Returning+From+Iraq%3A+Randomization+by+Platoon&rft.au=Adler%2C+Amy+B%3BBliese%2C+Paul+D%3BMcGurk%2C+Dennis%3BHoge%2C+Charles+W%3BCastro%2C+Carl+Andrew&rft.aulast=Adler&rft.aufirst=Amy&rft.date=2009-10-01&rft.volume=77&rft.issue=5&rft.spage=928&rft.isbn=&rft.btitle=&rft.title=Journal+of+Consulting+and+Clinical+Psychology&rft.issn=0022006X&rft_id=info:doi/10.1037%2Fa0016877 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2010-05-10 N1 - Last updated - 2016-09-27 N1 - CODEN - JCLPBC N1 - SubjectsTermNotLitGenreText - Symptoms; Early intervention programmes; Stress; Posttraumatic stress disorder; Debriefing; Iraq DO - http://dx.doi.org/10.1037/a0016877 ER - TY - JOUR T1 - Severe embryolethality of artesunate related to pharmacokinetics following intravenous and intramuscular doses in pregnant rats. AN - 734117950; 19851989 AB - Artesunate (AS), a rapid, effective, and safe antimalarial drug, has been used for the treatment of malaria for decades. However, severe embryolethality was found for injectable AS in pregnant animals. In the present study, pregnant rats were selected and dosed with AS (GMP product) intravenously (IV) and intramuscularly (IM) at varied doses daily for 13 days from gestation day (GD) 6 to 18. In addition, a toxic dose of 1.2 mg/kg/day was subsequently tested in the GD 6-10, GD 11-15, and GD 16-20 periods of rat pregnancy. A pharmacokinetic study was also conducted to evaluate the bioavailability of AS following the IM administrations. Results showed that no significant adverse effects were found in maternal rats. All of the fetuses were either damaged or reabsorbed by placentas in treated pregnant rats, but doses did not show an adverse effect at 0.4 and 0.5 mg/kg after IV and IM administrations, respectively. The survival rate of fetuses is dose-dependent and the 50% fetus re-absorption doses (FRD(50)) were 0.61 and 0.60 mg/kg following the IV and IM, respectively. The most drug-sensitive period, showing severe embryotoxicity, was between GD 11 and 15 for injectable AS. When calculated with total concentrations of AS and dihydroartemisinin, an active metabolite of AS, the bioavailability of 97.8% after intramuscular injection was fulfilled to a bioequivalence of that in intravenous treatment. The fact that injectable AS exhibited severe embryolethality after both IV and IM injections seems related to their comparable pharmacokinetic profiles that indicate high peak concentrations in pregnant animals. JF - Birth defects research. Part B, Developmental and reproductive toxicology AU - Li, Qigui AU - Si, Yuanzheng AU - Xie, Lisa AU - Zhang, Jing AU - Weina, Peter AD - Department of Pharmacology, Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20307-5100, USA. qigui.li@us.army.mil Y1 - 2009/10// PY - 2009 DA - October 2009 SP - 385 EP - 393 VL - 86 IS - 5 KW - Antimalarials KW - 0 KW - Artemisinins KW - artesunate KW - 60W3249T9M KW - Index Medicus KW - Rats KW - Spectrometry, Mass, Electrospray Ionization KW - Animals KW - Rats, Sprague-Dawley KW - Injections, Intravenous KW - Dose-Response Relationship, Drug KW - Injections, Intramuscular KW - Time Factors KW - Female KW - Chromatography, High Pressure Liquid KW - Pregnancy KW - Biological Availability KW - Antimalarials -- toxicity KW - Artemisinins -- toxicity KW - Embryo Loss -- metabolism KW - Embryo Loss -- chemically induced KW - Fetal Resorption -- chemically induced KW - Antimalarials -- blood KW - Embryo, Mammalian -- metabolism KW - Artemisinins -- pharmacokinetics KW - Embryo, Mammalian -- drug effects KW - Fetal Resorption -- metabolism KW - Artemisinins -- blood KW - Antimalarials -- pharmacokinetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/734117950?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Birth+defects+research.+Part+B%2C+Developmental+and+reproductive+toxicology&rft.atitle=Severe+embryolethality+of+artesunate+related+to+pharmacokinetics+following+intravenous+and+intramuscular+doses+in+pregnant+rats.&rft.au=Li%2C+Qigui%3BSi%2C+Yuanzheng%3BXie%2C+Lisa%3BZhang%2C+Jing%3BWeina%2C+Peter&rft.aulast=Li&rft.aufirst=Qigui&rft.date=2009-10-01&rft.volume=86&rft.issue=5&rft.spage=385&rft.isbn=&rft.btitle=&rft.title=Birth+defects+research.+Part+B%2C+Developmental+and+reproductive+toxicology&rft.issn=1542-9741&rft_id=info:doi/10.1002%2Fbdrb.20207 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-01-07 N1 - Date created - 2009-11-02 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1002/bdrb.20207 ER - TY - JOUR T1 - Reversible redox chemistry of quinones: impact on biogeochemical cycles. AN - 734062129; 19665164 AB - The role of quinone biomolecules and quinone moieties of natural organic matter (NOM) as the electron transfer mediator in essential biogeochemical processes such as iron bioreduction and contaminant degradation has received considerable interests in the past decade. Hypothesized electron shuttling mechanism must be evaluated based on the availability and stability of quinones under a given environmental setting. The goal of this review is to examine the source, reactivity, and fate of potential quinone catalysts with respect to chemical interactions (e.g., with other quinones and nucleophiles) that will inevitably occur in complex environmental media. We will first discuss natural and anthropogenic sources of quinones in aqueous environments, and fundamental transformation pathways including cross reaction, autoxidation, and addition reactions. We will then assess how the described sources (molecular structure) and transformation pathways (stability) will impact the ability of a quinone molecule to catalyze a biogeochemical process. Thermodynamics and kinetics of electron transfer reactions with both the electron donor (e.g., hydrogen sulfide as a bulk reductant) and the terminal electron acceptor (e.g., nitroaromatic explosives in contaminant degradation), and stability towards irreversible side reactions are the key factors determining the geochemical conditions under which the catalysis by a quinone molecule will be operative. JF - Chemosphere AU - Uchimiya, Minori AU - Stone, Alan T AD - Department of Geography and Environmental Engineering, Johns Hopkins University, Baltimore, MD 21218, United States. Minori.Uchimiya@usace.army.mil Y1 - 2009/10// PY - 2009 DA - October 2009 SP - 451 EP - 458 VL - 77 IS - 4 KW - Quinones KW - 0 KW - Water Pollutants, Chemical KW - Index Medicus KW - Oxidation-Reduction KW - Water Pollutants, Chemical -- chemistry KW - Thermodynamics KW - Kinetics KW - Environmental Restoration and Remediation KW - Water Pollutants, Chemical -- metabolism KW - Catalysis KW - Quinones -- chemistry KW - Quinones -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/734062129?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Chemosphere&rft.atitle=Reversible+redox+chemistry+of+quinones%3A+impact+on+biogeochemical+cycles.&rft.au=Uchimiya%2C+Minori%3BStone%2C+Alan+T&rft.aulast=Uchimiya&rft.aufirst=Minori&rft.date=2009-10-01&rft.volume=77&rft.issue=4&rft.spage=451&rft.isbn=&rft.btitle=&rft.title=Chemosphere&rft.issn=1879-1298&rft_id=info:doi/10.1016%2Fj.chemosphere.2009.07.025 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-01-06 N1 - Date created - 2009-09-28 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.chemosphere.2009.07.025 ER - TY - JOUR T1 - Pharmacokinetic profiles of artesunate after single intravenous doses at 0.5, 1, 2, 4, and 8 mg/kg in healthy volunteers: a phase I study. AN - 67685743; 19815876 AB - The pharmacokinetics of good manufacturing process injection of artesunate (AS) were evaluated after single doses at 0.5, 1, 2, 4, and 8 mg/kg with a 2-minute infusion in 40 healthy subjects. Drug concentrations were analyzed by validated liquid chromatography and mass spectrometry system (LC-MS/MS) procedures. The drug was immediately converted to dihydroartemisinin (DHA), with elimination half-lives ranging 0.12-0.24 and 1.15-2.37 hours for AS and DHA, respectively. Pharmacokinetic model-dependent analysis is suitable for AS, whereas DHA fits both model-dependent and -independent methods. Although DHA concentration was superior to that of AS with a 1.12-1.87 ratio of area under the curve (AUC)(DHA/AS), peak concentration of AS was much higher than that of DHA, with a 2.80- to 4.51-fold ratio of peak concentration (C(max AS/DHA)). Therefore, AS effectiveness has been attributed not only to its rapid hydrolysis to DHA, but also to itself high initial C(max). JF - The American journal of tropical medicine and hygiene AU - Li, Qigui AU - Cantilena, Louis R AU - Leary, Kevin J AU - Saviolakis, George A AU - Miller, R Scott AU - Melendez, Victor AU - Weina, Peter J AD - Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910-7500, USA. qigui.li@amedd.army.mil Y1 - 2009/10// PY - 2009 DA - October 2009 SP - 615 EP - 621 VL - 81 IS - 4 KW - Antimalarials KW - 0 KW - Artemisinins KW - artesunate KW - 60W3249T9M KW - Abridged Index Medicus KW - Index Medicus KW - Young Adult KW - Injections, Intravenous KW - Area Under Curve KW - Dose-Response Relationship, Drug KW - Humans KW - Adult KW - Middle Aged KW - Adolescent KW - Male KW - Female KW - Antimalarials -- administration & dosage KW - Antimalarials -- adverse effects KW - Artemisinins -- adverse effects KW - Antimalarials -- blood KW - Artemisinins -- pharmacokinetics KW - Artemisinins -- blood KW - Artemisinins -- administration & dosage KW - Antimalarials -- pharmacokinetics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67685743?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+American+journal+of+tropical+medicine+and+hygiene&rft.atitle=Pharmacokinetic+profiles+of+artesunate+after+single+intravenous+doses+at+0.5%2C+1%2C+2%2C+4%2C+and+8+mg%2Fkg+in+healthy+volunteers%3A+a+phase+I+study.&rft.au=Li%2C+Qigui%3BCantilena%2C+Louis+R%3BLeary%2C+Kevin+J%3BSaviolakis%2C+George+A%3BMiller%2C+R+Scott%3BMelendez%2C+Victor%3BWeina%2C+Peter+J&rft.aulast=Li&rft.aufirst=Qigui&rft.date=2009-10-01&rft.volume=81&rft.issue=4&rft.spage=615&rft.isbn=&rft.btitle=&rft.title=The+American+journal+of+tropical+medicine+and+hygiene&rft.issn=1476-1645&rft_id=info:doi/10.4269%2Fajtmh.2009.09-0150 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-10-27 N1 - Date created - 2009-10-09 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.4269/ajtmh.2009.09-0150 ER - TY - JOUR T1 - Nitrofurantoin-induced systemic inflammatory response syndrome. AN - 67683411; 19726971 AB - Nitrofurantoin is a commonly used antibiotic for the prophylaxis and treatment of urinary tract infections. We report the first case of nitrofurantoin-induced systemic inflammatory response syndrome, an important adverse drug reaction in the setting of what was initially believed to be a recurrent infection. JF - The American journal of the medical sciences AU - Forster, Christopher J AU - Cohee, Brian M AU - Wood-Morris, Robert N AU - Hartzell, Joshua D AD - Department of Medicine, Walter Reed Army Medical Center, Washington, DC 20307, USA. christopher.forster@amedd.army.mil Y1 - 2009/10// PY - 2009 DA - October 2009 SP - 338 EP - 340 VL - 338 IS - 4 KW - Nitrofurantoin KW - 927AH8112L KW - Abridged Index Medicus KW - Index Medicus KW - Humans KW - Escherichia coli Infections -- drug therapy KW - Urinary Bladder Neoplasms -- drug therapy KW - Aged KW - Antineoplastic Combined Chemotherapy Protocols -- therapeutic use KW - Male KW - Urinary Bladder Neoplasms -- complications KW - Escherichia coli Infections -- complications KW - Systemic Inflammatory Response Syndrome -- complications KW - Systemic Inflammatory Response Syndrome -- chemically induced KW - Nitrofurantoin -- adverse effects KW - Gram-Negative Bacterial Infections -- drug therapy KW - Gram-Negative Bacterial Infections -- microbiology KW - Nitrofurantoin -- therapeutic use KW - Stenotrophomonas -- isolation & purification UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67683411?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+American+journal+of+the+medical+sciences&rft.atitle=Nitrofurantoin-induced+systemic+inflammatory+response+syndrome.&rft.au=Forster%2C+Christopher+J%3BCohee%2C+Brian+M%3BWood-Morris%2C+Robert+N%3BHartzell%2C+Joshua+D&rft.aulast=Forster&rft.aufirst=Christopher&rft.date=2009-10-01&rft.volume=338&rft.issue=4&rft.spage=338&rft.isbn=&rft.btitle=&rft.title=The+American+journal+of+the+medical+sciences&rft.issn=1538-2990&rft_id=info:doi/10.1097%2FMAJ.0b013e3181abd9f6 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-10-26 N1 - Date created - 2009-10-14 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1097/MAJ.0b013e3181abd9f6 ER - TY - JOUR T1 - Prospective assessment of neuropsychological functioning and mood in US Army National Guard personnel deployed as peacekeepers. AN - 67631895; 19730757 AB - The present study examined the impact of deployment on neuropsychological functioning and mood in Army National Guard personnel. We hypothesized that deployment on a peacekeeping mission, compared to non-deployment, would result in reduced proficiencies in neuropsychological performance and negative mood changes, and that such changes would relate to working in a high-strain job (high demands/low control), in accordance with Karasek's demand-control model. This prospective cohort study involved 119 male soldiers (67 participants examined before and after deployment to the Bosnia operational theatre and 52 non-deployed soldiers assessed twice over a comparable period). Unit-level adjusted, multivariate analyses found that deployed soldiers, compared to their non-deployed counterparts, demonstrated reduced proficiency in tasks involving motor speed [unstandardized coefficient B= -3.88, 95% confidence interval (95% CI) -6.38- -1.39; B= -3.84, 95% CI -5.55- -2.14; dominant and non-dominant hand, respectively] and sustained attention (B=0.031, 95% CI 0.009-0.054), along with decreased vigor (B= -2.71, 95% CI -3.63- -1.77). Deployed soldiers also showed improved proficiency in a working-memory task (B= -0.098, 95% CI -0.136- -0.060) with less depression symptomatology (B= -3.19, 95% CI -5.26- -1.13). Work stress levels increased over time in both deployed and non-deployed groups, but observed deployment effects remained significant after accounting for a high-strain job. The observed change in performance associated with peacekeeping deployment compared to non-deployment (slowed processing speed, reduced motor speed and reported vigor, together with improved proficiency in a working memory task) suggests an adaptive response to mission occupational stressors. This pattern does not appear to be influenced by working in a high-strain job. Further study is required to examine whether these results reflect transient or permanent changes in functioning. JF - Scandinavian journal of work, environment & health AU - Proctor, Susan P AU - Heaton, Kristin J AU - Dos Santos, Kathryn Dutille AU - Rosenman, Erik S AU - Heeren, Timothy AD - Military Performance Division, US Army Research Institute of Environmental Medicine, Kansas St, Building 42, Natick, MA 01760, United States. susan.proctor@us.army.mil Y1 - 2009/10// PY - 2009 DA - October 2009 SP - 349 EP - 360 VL - 35 IS - 5 SN - 0355-3140, 0355-3140 KW - Index Medicus KW - United States KW - Socioeconomic Factors KW - Occupational Health KW - Age Factors KW - Prospective Studies KW - Humans KW - Health Status KW - Neuropsychological Tests KW - Male KW - Military Personnel -- psychology KW - Occupational Diseases -- epidemiology KW - Mental Health KW - Affect KW - Stress, Psychological -- epidemiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67631895?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Scandinavian+journal+of+work%2C+environment+%26+health&rft.atitle=Prospective+assessment+of+neuropsychological+functioning+and+mood+in+US+Army+National+Guard+personnel+deployed+as+peacekeepers.&rft.au=Proctor%2C+Susan+P%3BHeaton%2C+Kristin+J%3BDos+Santos%2C+Kathryn+Dutille%3BRosenman%2C+Erik+S%3BHeeren%2C+Timothy&rft.aulast=Proctor&rft.aufirst=Susan&rft.date=2009-10-01&rft.volume=35&rft.issue=5&rft.spage=349&rft.isbn=&rft.btitle=&rft.title=Scandinavian+journal+of+work%2C+environment+%26+health&rft.issn=03553140&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-10-14 N1 - Date created - 2009-09-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Being a Reserve Soldier AN - 60016324; 200943329 AB - Drawing on social identity theory, the present article examines the extent to which soldier identification with the small unit is related to outcomes having increased importance to reserve military service. Measures of social identity have stronger associations with unit membership, whereas measures of personal identity do not. Soldiers' reports of positive experiences when first entering the unit are more strongly and positively related to measures of social identity than to measures of personal identity. Measures of social identity show positive relationships with group-relevant outcomes, such as commitment to the unit and perceived readiness of the unit and fellow soldiers. Measures of personal identity show positive relationships with individually relevant outcomes, such as reporting for duty for contractual reasons and letting their families down and perceived personal readiness for combat. Results imply improving specific small-unit relations and developing abstract beliefs to increase reservists' perceived readiness and commitment to their part-time military service. [Reprinted by permission; copyright Inter-University Seminar on Armed Forces and Society/Sage Publications Inc.] JF - Armed Forces & Society AU - Griffith, James AD - Maryland Army National Guard GriffithJH@verizon.net Y1 - 2009/10// PY - 2009 DA - October 2009 SP - 38 EP - 64 PB - Sage Publications, Thousand Oaks CA VL - 36 IS - 1 SN - 0095-327X, 0095-327X KW - reserve military service social identity reservist identity readiness retention KW - Social Identity KW - Self Concept KW - Membership KW - Military Personnel KW - Military Service KW - article KW - 0623: complex organization; military sociology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/60016324?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocabs&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Armed+Forces+%26+Society&rft.atitle=Being+a+Reserve+Soldier&rft.au=Griffith%2C+James&rft.aulast=Griffith&rft.aufirst=James&rft.date=2009-10-01&rft.volume=36&rft.issue=1&rft.spage=38&rft.isbn=&rft.btitle=&rft.title=Armed+Forces+%26+Society&rft.issn=0095327X&rft_id=info:doi/10.1177%2F0095327X08327819 LA - English DB - Sociological Abstracts N1 - Date revised - 2010-10-21 N1 - Last updated - 2016-09-28 N1 - CODEN - AFSOD2 N1 - SubjectsTermNotLitGenreText - Social Identity; Military Personnel; Self Concept; Military Service; Membership DO - http://dx.doi.org/10.1177/0095327X08327819 ER - TY - JOUR T1 - Estimating modulus values for layers in a flexible pavement incorporating a geocomposite capillary barrier drain AN - 50119260; 2010-006568 JF - ERDC/CRREL Letter Report AU - Barna, Lynette A AU - Henry, Karen S AU - Solano Velez, Deborah M AU - Stormont, John C Y1 - 2009/10// PY - 2009 DA - October 2009 SP - 62 PB - U. S. Army Cold Regions Research and Engineering Laboratory, Hanover, NH KW - United States KW - soil mechanics KW - Minnesota KW - loading KW - Saint Paul Minnesota KW - freezing KW - cold weather construction KW - mitigation KW - safety KW - Ramsey County Minnesota KW - New England KW - winter maintenance KW - roads KW - construction materials KW - field studies KW - 30:Engineering geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50119260?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/GeoRef&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=Barna%2C+Lynette+A%3BHenry%2C+Karen+S%3BSolano+Velez%2C+Deborah+M%3BStormont%2C+John+C&rft.aulast=Barna&rft.aufirst=Lynette&rft.date=2009-10-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=Estimating+modulus+values+for+layers+in+a+flexible+pavement+incorporating+a+geocomposite+capillary+barrier+drain&rft.title=Estimating+modulus+values+for+layers+in+a+flexible+pavement+incorporating+a+geocomposite+capillary+barrier+drain&rft.issn=&rft_id=info:doi/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2010-01-01 N1 - Number of references - 10 N1 - PubXState - NH N1 - Document feature - illus. incl. 8 tables N1 - SuppNotes - Includes 2 appendices N1 - Last updated - 2012-06-07 N1 - CODEN - #05693 N1 - SubjectsTermNotLitGenreText - cold weather construction; construction materials; field studies; freezing; loading; Minnesota; mitigation; New England; Ramsey County Minnesota; roads; safety; Saint Paul Minnesota; soil mechanics; United States; winter maintenance ER - TY - JOUR T1 - Structural improvements of flexible pavements using geosynthetics for base course reinforcement AN - 50119191; 2010-006570 JF - ERDC/CRREL Technical Report AU - Henry, Karen S AU - Clapp, Joshua AU - Davids, William AU - Humphrey, Dana AU - Barna, Lynette A Y1 - 2009/10// PY - 2009 DA - October 2009 SP - 182 PB - U. S. Army Corps of Engineers, Engineer Research and Development Center, Hanover, NH KW - civil engineering KW - soil mechanics KW - asphalt KW - mechanical properties KW - transportation KW - models KW - cold weather construction KW - bitumens KW - water content KW - geogrids KW - construction KW - synthetic materials KW - roads KW - design KW - construction materials KW - 30:Engineering geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50119191?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/GeoRef&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=Henry%2C+Karen+S%3BClapp%2C+Joshua%3BDavids%2C+William%3BHumphrey%2C+Dana%3BBarna%2C+Lynette+A&rft.aulast=Henry&rft.aufirst=Karen&rft.date=2009-10-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=Structural+improvements+of+flexible+pavements+using+geosynthetics+for+base+course+reinforcement&rft.title=Structural+improvements+of+flexible+pavements+using+geosynthetics+for+base+course+reinforcement&rft.issn=&rft_id=info:doi/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2014, American Geosciences Institute. N1 - Date revised - 2010-01-01 N1 - Number of references - 45 N1 - PubXState - NH N1 - Document feature - illus. incl. 22 tables N1 - SuppNotes - Transportation Pooled Fund Program; includes 4 appendices N1 - Last updated - 2014-09-18 N1 - CODEN - #05435 N1 - SubjectsTermNotLitGenreText - asphalt; bitumens; civil engineering; cold weather construction; construction; construction materials; design; geogrids; mechanical properties; models; roads; soil mechanics; synthetic materials; transportation; water content ER - TY - CPAPER T1 - The Way Forward? Analysis of the International Healthcare Landscape to Guide the Future of the U.S. Healthcare System T2 - Sixteenth Annual South Dakota International Business Conference AN - 42423574; 5395988 JF - Sixteenth Annual South Dakota International Business Conference AU - Beauvais, Brad AU - Brezinski, Paul Y1 - 2009/10/01/ PY - 2009 DA - 2009 Oct 01 KW - USA KW - Health care KW - Landscape KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42423574?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Sixteenth+Annual+South+Dakota+International+Business+Conference&rft.atitle=The+Way+Forward%3F+Analysis+of+the+International+Healthcare+Landscape+to+Guide+the+Future+of+the+U.S.+Healthcare+System&rft.au=Beauvais%2C+Brad%3BBrezinski%2C+Paul&rft.aulast=Beauvais&rft.aufirst=Brad&rft.date=2009-10-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Sixteenth+Annual+South+Dakota+International+Business+Conference&rft.issn=&rft_id=info:doi/ L2 - http://www3.northern.edu/ceib/ibc/mat/In%20Process%20Conference%20Sche dule.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Novel Broad-Spectrum Bis-(Imidazolinylindole) Derivatives with Potent Antibacterial Activities against Antibiotic-Resistant Strains , AN - 21482887; 12492384 AB - Given the limited number of structural classes of clinically available antimicrobial drugs, the discovery of antibacterials with novel chemical scaffolds is an important strategy in the development of effective therapeutics for both naturally occurring and engineered resistant strains of pathogenic bacteria. In this study, several diarylamidine derivatives were evaluated for their ability to protect macrophages from cell death following infection with Bacillus anthracis, a gram-positive spore-forming bacterium. Four bis-(imidazolinylindole) compounds were identified with potent antibacterial activity as measured by the protection of macrophages and by the inhibition of bacterial growth in vitro. These compounds were effective against a broad range of gram-positive and gram-negative bacterial species, including several antibiotic-resistant strains. Minor structural variations among the four compounds correlated with differences in their effects on bacterial macromolecular synthesis and mechanisms of resistance. In vivo studies revealed protection by two of the compounds of mice lethally infected with B. anthracis, Staphylococcus aureus, or Yersinia pestis. Taken together, these results indicate that the bis-(imidazolinylindole) compounds represent a new chemotype for the development of therapeutics for both gram-positive and gram-negative bacterial species as well as against antibiotic-resistant infections. JF - Antimicrobial Agents & Chemotherapy AU - Panchal, Rekha G AU - Ulrich, Ricky L AU - Lane, Douglas AU - Butler, Michelle M AU - Houseweart, Chad AU - Opperman, Timothy AU - Williams, John D AU - Peet, Norton P AU - Moir, Donald T AU - Nguyen, Tam AU - Gussio, Rick AU - Bowlin, Terry AU - Bavari, Sina AD - United States Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Fort Detrick, Frederick, Maryland 21702-5011, rekha.panchal@amedd.army.mil rekha.panchal@amedd.army.mil rekha.panchal@amedd.army.mil rekha.panchal@amedd.army.mil Y1 - 2009/10// PY - 2009 DA - Oct 2009 SP - 4283 EP - 4291 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 53 IS - 10 SN - 0066-4804, 0066-4804 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Biotechnology and Bioengineering Abstracts; Microbiology Abstracts B: Bacteriology KW - Macrophages KW - Macromolecules KW - Antibacterial activity KW - Yersinia pestis KW - Drug development KW - Bacillus anthracis KW - Infection KW - scaffolds KW - Antimicrobial agents KW - Drug discovery KW - Cell death KW - Staphylococcus aureus KW - A 01340:Antibiotics & Antimicrobials KW - W 30915:Pharmaceuticals & Vaccines KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21482887?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+Agents+%26+Chemotherapy&rft.atitle=Novel+Broad-Spectrum+Bis-%28Imidazolinylindole%29+Derivatives+with+Potent+Antibacterial+Activities+against+Antibiotic-Resistant+Strains+%2C&rft.au=Panchal%2C+Rekha+G%3BUlrich%2C+Ricky+L%3BLane%2C+Douglas%3BButler%2C+Michelle+M%3BHouseweart%2C+Chad%3BOpperman%2C+Timothy%3BWilliams%2C+John+D%3BPeet%2C+Norton+P%3BMoir%2C+Donald+T%3BNguyen%2C+Tam%3BGussio%2C+Rick%3BBowlin%2C+Terry%3BBavari%2C+Sina&rft.aulast=Panchal&rft.aufirst=Rekha&rft.date=2009-10-01&rft.volume=53&rft.issue=10&rft.spage=4283&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+Agents+%26+Chemotherapy&rft.issn=00664804&rft_id=info:doi/10.1128%2FAAC.01709-08 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2013-05-31 N1 - SubjectsTermNotLitGenreText - Macrophages; Drug discovery; Macromolecules; Cell death; Antibacterial activity; Drug development; Infection; scaffolds; Antimicrobial agents; Yersinia pestis; Staphylococcus aureus; Bacillus anthracis DO - http://dx.doi.org/10.1128/AAC.01709-08 ER - TY - JOUR T1 - Intravascular Ultrasound-Guided Inferior Vena Cava Filter Placement in the Military Multitrauma Patients: A Single-Center Experience AN - 21318472; 12508344 AB - Background: High velocity fragments have resulted in a multitude of complex injuries in the military patients, placing them at increased risk of venous thromboembolism. Methods: A retrospective analysis was performed of all the intravascular ultrasound (IVUS)-guided bedside inferior vena cava (IVC) filters placed between August 2003 and October 2007. Results: Fourteen patients had bedside IVUS-guided retrievable filter placement. Thirteen males and one female and the mean (+SD) injury severity scores (ISS) was 37.2 (+9.9). The most common causes of injury were explosive devices (57%), gunshot wounds (28%), rocket-propelled grenades (7%), and motor vehicle crashes (7%). Indications for filter insertion were deep venous thrombosis in 36% of patients and pulmonary embolus in 28%. Thirty five percent had filters inserted prophylactically. Conclusions: Military trauma population ISS is considerably higher than what is reported in the civilian population. The bedside IVUS-guided IVC filter insertion is particularly useful in this population. JF - Vascular and Endovascular Surgery AU - Aidinian, Gilbert AU - Fox, Charles J AU - White, Paul W AU - Cox, Mitchell W AU - Adams, Eric D AU - Gillespie, David L AD - Department of Surgery, Peripheral Vascular Surgery Service, Walter Reed Army Medical Center, Washington, D.C., gilbert.aidinian@us.army.mil Y1 - 2009/10// PY - 2009 DA - Oct 2009 SP - 497 EP - 501 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU UK VL - 43 IS - 5 SN - 1538-5744, 1538-5744 KW - Biotechnology and Bioengineering Abstracts KW - inferior vena cava filter KW - trauma KW - intravascular ultrasound KW - Cardiovascular system KW - Injuries KW - Motor vehicles KW - Thromboembolism KW - Thrombosis KW - Trauma KW - Wounds KW - Filters KW - Lung KW - Embolism KW - Explosives KW - Ultrasound KW - Vascular system KW - W 30910:Imaging UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21318472?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vascular+and+Endovascular+Surgery&rft.atitle=Intravascular+Ultrasound-Guided+Inferior+Vena+Cava+Filter+Placement+in+the+Military+Multitrauma+Patients%3A+A+Single-Center+Experience&rft.au=Aidinian%2C+Gilbert%3BFox%2C+Charles+J%3BWhite%2C+Paul+W%3BCox%2C+Mitchell+W%3BAdams%2C+Eric+D%3BGillespie%2C+David+L&rft.aulast=Aidinian&rft.aufirst=Gilbert&rft.date=2009-10-01&rft.volume=43&rft.issue=5&rft.spage=497&rft.isbn=&rft.btitle=&rft.title=Vascular+and+Endovascular+Surgery&rft.issn=15385744&rft_id=info:doi/10.1177%2F1538574409334824 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Cardiovascular system; Injuries; Motor vehicles; Thrombosis; Thromboembolism; Wounds; Trauma; Filters; Embolism; Lung; Explosives; Ultrasound; Vascular system DO - http://dx.doi.org/10.1177/1538574409334824 ER - TY - JOUR T1 - Community-Associated Methicillin-Resistant Staphylococcus aureus Mediastinitis AN - 21309869; 12511541 AB - Community-associated methicillin (meticillin)-resistant Staphylococcus aureus (CA-MRSA) continues to emerge as a cause of serious infections, chiefly of the skin and soft tissues. We present the first documented case of CA-MRSA mediastinitis in an adult. Blood and mediastinal isolates were characterized as CA-MRSA by pulsed-field gel electrophoresis and susceptibility testing. JF - Journal of Clinical Microbiology AU - Calvano, Tatjana P AU - Ferraro, David M AU - Prakash, Vidhya AU - Mende, Katrin AU - Hospenthal, Duane R AD - Department of Medicine, San Antonio Military Medical Center, Fort Sam Houston, Texas, duane.hospenthal@amedd.army.mil Y1 - 2009/10// PY - 2009 DA - Oct 2009 SP - 3367 EP - 3369 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 47 IS - 10 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Blood KW - Skin KW - Methicillin KW - Drug resistance KW - Pulsed-field gel electrophoresis KW - Staphylococcus aureus KW - Mediastinitis KW - Infection KW - Soft tissues KW - J 02340:Antibiotics & Antimicrobials UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21309869?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Community-Associated+Methicillin-Resistant+Staphylococcus+aureus+Mediastinitis&rft.au=Calvano%2C+Tatjana+P%3BFerraro%2C+David+M%3BPrakash%2C+Vidhya%3BMende%2C+Katrin%3BHospenthal%2C+Duane+R&rft.aulast=Calvano&rft.aufirst=Tatjana&rft.date=2009-10-01&rft.volume=47&rft.issue=10&rft.spage=3367&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.00872-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2013-07-15 N1 - SubjectsTermNotLitGenreText - Blood; Methicillin; Skin; Drug resistance; Pulsed-field gel electrophoresis; Infection; Mediastinitis; Soft tissues; Staphylococcus aureus DO - http://dx.doi.org/10.1128/JCM.00872-09 ER - TY - JOUR T1 - Site and Clinical Significance of Alloscardovia omnicolens and Bifidobacterium Species Isolated in the Clinical Laboratory AN - 21281028; 12511505 AB - Most of the members of the genus Bifidobacterium, including the related organism Alloscardovia omnicolens, are inhabitants of the gastrointestinal tract and oral cavity of humans and animals and have been considered nonpathogenic for humans. However, the actual site of isolation and the clinical significance of A. omnicolens and of Bifidobacterium species are unclear. This may be due in part to the difficulties in distinguishing these organisms from other genera such as Actinomyces. To determine the potential disease-causing role of these organisms, we analyzed the clinical significance of 15 A. omnicolens and Bifidobacterium isolates identified by 16S rRNA gene sequencing from a clinical laboratory. All of the organisms in this study were isolated from sterile sites or in significant numbers by standard clinical microbiological culture methods. Our 15 clinical strains fit into only four species: A. omnicolens (five isolates), Bifidobacterium scardovii (four isolates), B. longum (two isolates), and B. breve (four isolates). All five A. omnicolens isolates, one of the B. breve isolates, and three of the four B. scardovii isolates were cultured from urine at 105 CFU/ml. One B. scardovii isolate was from a patient with a genitourinary tract wound infection, two B. longum isolates were from abdominal wounds, and three B. breve isolates were from blood cultures. This study enlarges the spectrum of diseases and clinical sources associated with A. omnicolens and Bifidobacterium species and addresses identification problems. JF - Journal of Clinical Microbiology AU - Mahlen, Steven D AU - Clarridge III, Jill E AD - U.S. Army Medical Corps with duty at the Department of Laboratory Medicine, University of Washington, Seattle, Washington, jill.clarridge@va.gov Y1 - 2009/10// PY - 2009 DA - Oct 2009 SP - 3289 EP - 3293 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 47 IS - 10 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Blood culture KW - Urine KW - Wound infection KW - Colony-forming cells KW - Genitourinary tract KW - Gastrointestinal tract KW - rRNA 16S KW - Actinomyces KW - Oral cavity KW - Bifidobacterium KW - Wounds KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21281028?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Site+and+Clinical+Significance+of+Alloscardovia+omnicolens+and+Bifidobacterium+Species+Isolated+in+the+Clinical+Laboratory&rft.au=Mahlen%2C+Steven+D%3BClarridge+III%2C+Jill+E&rft.aulast=Mahlen&rft.aufirst=Steven&rft.date=2009-10-01&rft.volume=47&rft.issue=10&rft.spage=3289&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.00555-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2013-07-15 N1 - SubjectsTermNotLitGenreText - Blood culture; Wound infection; Urine; Colony-forming cells; Genitourinary tract; Gastrointestinal tract; rRNA 16S; Oral cavity; Wounds; Actinomyces; Bifidobacterium DO - http://dx.doi.org/10.1128/JCM.00555-09 ER - TY - JOUR T1 - Efficient methods for large-area surface sampling of sites contaminated with pathogenic microorganisms and other hazardous agents: current state, needs, and perspectives AN - 21260734; 11726880 AB - The recovery operations following the 2001 attacks with Bacillus anthracis spores were complicated due to the unprecedented need for large-area surface sampling and decontamination protocols. Since this event, multiple reports have been published describing recovery efficiencies of several surface sampling materials. These materials include fibrous swabs of various compositions, cloth wipes, vacuum socks, and adhesive tapes. These materials have reported recovery efficiencies ranging from approximately 20% to 90% due to the many variations in their respective studies including sampling material, composition of surface sampled, concentration of contaminant, and even the method of deposition and sample processing. Additionally, the term recovery efficiency is crudely defined and could be better constructed to incorporate variations in contaminated surface composition and end user needs. While significant efforts in devising protocols for large-area surface sampling have been undertaken in the years since the anthrax attacks, there is still a general lack of consensus in optimal sampling materials and the methodology in which they are evaluated. Fortunately, sampling efforts are continuing to be supported, and the knowledge gaps in our procedures, methodology, and general understanding of sampling mechanisms are being investigated which will leave us better prepared for the future. JF - Applied Microbiology and Biotechnology AU - Edmonds, Jason M AD - Edgewood Chemical Biological Center, United States Army, Department of Defense, 5183 Blackhawk Road, Aberdeen Proving Grounds, APGEA, MD, 21010, USA, Jason.Edmonds1@us.army.mil Y1 - 2009/10// PY - 2009 DA - Oct 2009 SP - 811 EP - 816 PB - Springer-Verlag, Heidelberger Platz 3 Berlin 14197 Germany VL - 84 IS - 5 SN - 0175-7598, 0175-7598 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Biotechnology and Bioengineering Abstracts KW - Vacuum KW - Decontamination KW - anthrax KW - Bacillus anthracis KW - Efficiency KW - Microorganisms KW - Anthrax KW - Sampling KW - Contaminants KW - Adhesives KW - Spores KW - Biotechnology KW - A 01490:Miscellaneous KW - W 30900:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21260734?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+Microbiology+and+Biotechnology&rft.atitle=Efficient+methods+for+large-area+surface+sampling+of+sites+contaminated+with+pathogenic+microorganisms+and+other+hazardous+agents%3A+current+state%2C+needs%2C+and+perspectives&rft.au=Edmonds%2C+Jason+M&rft.aulast=Edmonds&rft.aufirst=Jason&rft.date=2009-10-01&rft.volume=84&rft.issue=5&rft.spage=811&rft.isbn=&rft.btitle=&rft.title=Applied+Microbiology+and+Biotechnology&rft.issn=01757598&rft_id=info:doi/10.1007%2Fs00253-009-2136-z LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-01-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Microorganisms; Decontamination; Vacuum; Anthrax; Sampling; Spores; Adhesives; Contaminants; Efficiency; anthrax; Biotechnology; Bacillus anthracis DO - http://dx.doi.org/10.1007/s00253-009-2136-z ER - TY - JOUR T1 - Influence of landscape restoration and degradation on storm surge and waves in southern Louisiana AN - 21258759; 11717832 AB - The purpose of this investigation was to examine storm surge and wave reduction benefits of different environmental restoration features (marsh restoration and barrier island changes), as well as the impact of future wetland degradation on local surge and wave conditions. Storm surge simulations of two representative hurricanes were performed using the ADCIRC storm surge model with the inclusion of radiation stress gradients from the STWAVE nearshore wave model. Coupled model simulations were made for a number of landscape configurations that involved both restored and degraded wetland features. The impact of barrier island condition on hurricane surge and waves was also evaluated. Effects of landscape features were represented by changes in elevation and frictional resistance. Restoration and degradation of marsh resulted in decreases (for restoration cases) and increases (for degradation cases) in both surge and waves. The magnitude of change was correlated with the magnitude of the horizontal extent and elevation changes in the marsh. In general, the wave change patterns are consistent with the water level changes. Deflation of the Chandeleur Islands (barrier island chain) resulted in slightly increased surge. Results suggest that coastal marsh does have surge and wave reduction potential. Results also indicate that the impact of the landscape features is amplified in areas where there are levee 'pockets.' Barrier islands and coastal ridges reduce wave heights, even if in a degraded condition and thus can reduce wave energy in wetland areas, protecting them from erosion. JF - Natural Hazards AU - Wamsley, Ty V AU - Cialone, Mary A AU - Smith, Jane M AU - Ebersole, Bruce A AU - Grzegorzewski, Alison S AD - U.S. Army Engineer Research & Development Center, 3909 Halls Ferry Rd., Vicksburg, MS, 39180, USA Y1 - 2009/10// PY - 2009 DA - Oct 2009 SP - 207 EP - 224 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 51 IS - 1 SN - 0921-030X, 0921-030X KW - Sustainability Science Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Environment Abstracts; Meteorological & Geoastrophysical Abstracts KW - ASW, USA, Louisiana KW - Degradation KW - Storms KW - Islands KW - Radiation KW - Storm surge models KW - Wetlands KW - Topography KW - barrier islands KW - Landscape KW - Surges KW - Stress KW - Simulation KW - Hurricane surges KW - Wave models KW - Marshes KW - wave energy KW - Ecosystem disturbance KW - Hurricanes KW - Erosion KW - water levels KW - ridges KW - Shore protection KW - Numerical simulations KW - Storm surges KW - Habitat improvement KW - Wave height KW - Coastal oceanography KW - Environmental restoration KW - Barrier islands KW - Coastal ridges KW - M2 551.515.2:Cyclones Hurricanes Typhoons (551.515.2) KW - ENA 03:Energy KW - Q2 09271:Coastal morphology KW - M3 1010:Issues in Sustainable Development KW - M2 551.466:Ocean Waves and Tides (551.466) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21258759?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Natural+Hazards&rft.atitle=Influence+of+landscape+restoration+and+degradation+on+storm+surge+and+waves+in+southern+Louisiana&rft.au=Wamsley%2C+Ty+V%3BCialone%2C+Mary+A%3BSmith%2C+Jane+M%3BEbersole%2C+Bruce+A%3BGrzegorzewski%2C+Alison+S&rft.aulast=Wamsley&rft.aufirst=Ty&rft.date=2009-10-01&rft.volume=51&rft.issue=1&rft.spage=207&rft.isbn=&rft.btitle=&rft.title=Natural+Hazards&rft.issn=0921030X&rft_id=info:doi/10.1007%2Fs11069-009-9378-z LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Shore protection; Storm surges; Habitat improvement; Wave height; Surges; Wetlands; Barrier islands; Marshes; Ecosystem disturbance; Hurricane surges; Wave models; Hurricanes; Erosion; Numerical simulations; Radiation; Storm surge models; Coastal oceanography; Coastal ridges; Topography; barrier islands; Degradation; Landscape; Simulation; Stress; Storms; wave energy; ridges; water levels; Islands; Environmental restoration; ASW, USA, Louisiana DO - http://dx.doi.org/10.1007/s11069-009-9378-z ER - TY - JOUR T1 - Development of Field-Based Real-Time Reverse Transcription-Polymerase Chain Reaction Assays for Detection of Chikungunya and O'nyong-nyong Viruses in Mosquitoes AN - 21258706; 11848159 AB - Chikungunya (CHIK) and O'nyong-nyong (ONN) are important emerging arthropod-borne diseases. Molecular diagnosis of these two viruses in mosquitoes has not been evaluated, and the effects of extraneous mosquito tissue on assay performance have not been tested. Additionally, no real-time reverse transcription-polymerase chain reaction (RT-PCR) assay exists for detecting ONN virus (ONNV) RNA. We describe the development of sensitive and specific real-time RT-PCR assays for detecting CHIK and ONN viral RNA in mosquitoes, which have application for field use. In addition, we compared three methods for primer/probe design for assay development by evaluating their sensitivity and specificity. This comparison resulted in development of virus-specific assays that could detect less than one plaque-forming unit equivalent of each of the viruses in mosquitoes. The use of these assays will aid in arthropod-borne disease surveillance and in the control of the associated diseases. JF - American Journal of Tropical Medicine and Hygiene AU - Smith AU - Lee, J S AU - Jahrling, J AU - Kulesh, DA AU - Turell, MJ AU - Groebner, J L AU - O'Guinn, M L AD - Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702, USA, monica.oguinn@us.army.mil Y1 - 2009/10// PY - 2009 DA - October 2009 SP - 679 EP - 684 PB - American Society of Tropical Medicine and Hygiene, 60 Revere Drive, Suite 500 Northbrook IL 60062 USA, [mailto:astmh@astmh.org], [URL:http://www.astmh.org/] VL - 81 IS - 4 SN - 0002-9637, 0002-9637 KW - Microbiology Abstracts C: Algology, Mycology & Protozoology; Microbiology Abstracts B: Bacteriology; ASFA 3: Aquatic Pollution & Environmental Quality; Biochemistry Abstracts 2: Nucleic Acids; Virology & AIDS Abstracts; ASFA 1: Biological Sciences & Living Resources; Entomology Abstracts KW - Biological surveys KW - DNA probes KW - Viruses KW - Disease control KW - Culicidae KW - RNA viruses KW - Pest control KW - Public health KW - RNA KW - Polymerase chain reaction KW - Primers KW - Disease detection KW - Hygiene KW - Aquatic insects KW - J 02410:Animal Diseases KW - V 22300:Methods KW - K 03300:Methods KW - Q1 08484:Species interactions: parasites and diseases KW - Z 05350:Medical, Veterinary, and Agricultural Entomology KW - Q5 08524:Public health, medicines, dangerous organisms KW - N 14810:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21258706?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.atitle=Development+of+Field-Based+Real-Time+Reverse+Transcription-Polymerase+Chain+Reaction+Assays+for+Detection+of+Chikungunya+and+O%27nyong-nyong+Viruses+in+Mosquitoes&rft.au=Smith%3BLee%2C+J+S%3BJahrling%2C+J%3BKulesh%2C+DA%3BTurell%2C+MJ%3BGroebner%2C+J+L%3BO%27Guinn%2C+M+L&rft.aulast=Smith&rft.aufirst=&rft.date=2009-10-01&rft.volume=81&rft.issue=4&rft.spage=679&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Tropical+Medicine+and+Hygiene&rft.issn=00029637&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - Last updated - 2016-05-13 N1 - SubjectsTermNotLitGenreText - Biological surveys; Viruses; Disease control; Polymerase chain reaction; Pest control; Disease detection; Hygiene; Aquatic insects; Public health; RNA; DNA probes; RNA viruses; Primers; Culicidae ER - TY - JOUR T1 - A surge response function approach to coastal hazard assessment - part 1: basic concepts AN - 21253617; 11717833 AB - This paper reviews historical methods for estimating surge hazards and concludes that the class of solutions produced with Joint Probability Method (JPM) solutions provides a much more stable estimate of hazard levels than alternative methods. We proceed to describe changes in our understanding of the winds in hurricanes approaching a coast and the physics of surge generation that have required recent modifications to procedures utilized in earlier JPM studies. Of critical importance to the accuracy of hazard estimates is the ability to maintain a high level of fidelity in the numerical simulations while allowing for a sufficient number of simulations to populate the joint probability matrices for the surges. To accomplish this, it is important to maximize the information content in the sample storm set to be simulated. This paper introduces the fundamentals of a method based on the functional specification of the surge response for this purpose, along with an example of its application in the New Orleans area. A companion paper in this special issue (Irish et al. 2009) provides details of the portion of this new method related to interpolating/extrapolating along spatial dimensions. JF - Natural Hazards AU - Resio, Donald T AU - Irish, Jennifer AU - Cialone, Mary AD - ERDC-CHL, Vicksburg, MS, USA, donald.t.resio@usace.army.mil Y1 - 2009/10// PY - 2009 DA - Oct 2009 SP - 163 EP - 182 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 51 IS - 1 SN - 0921-030X, 0921-030X KW - Sustainability Science Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources; Environment Abstracts; Meteorological & Geoastrophysical Abstracts KW - Historical account KW - Surges KW - Simulation KW - Surge response KW - USA, Louisiana, New Orleans KW - Storms KW - Hazards KW - Hurricanes KW - Coastal zone KW - Numerical simulations KW - Storm surges KW - Reviews KW - coastal hazards KW - Hazard assessment KW - M2 551.515.2:Cyclones Hurricanes Typhoons (551.515.2) KW - Q2 09243:Structure, mechanics and thermodynamics KW - M3 1010:Issues in Sustainable Development KW - ENA 12:Oceans & Estuaries UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21253617?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Natural+Hazards&rft.atitle=A+surge+response+function+approach+to+coastal+hazard+assessment+-+part+1%3A+basic+concepts&rft.au=Resio%2C+Donald+T%3BIrish%2C+Jennifer%3BCialone%2C+Mary&rft.aulast=Resio&rft.aufirst=Donald&rft.date=2009-10-01&rft.volume=51&rft.issue=1&rft.spage=163&rft.isbn=&rft.btitle=&rft.title=Natural+Hazards&rft.issn=0921030X&rft_id=info:doi/10.1007%2Fs11069-009-9379-y LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-02-01 N1 - Last updated - 2014-05-07 N1 - SubjectsTermNotLitGenreText - Hazards; Hurricanes; Coastal zone; Surges; Surge response; Storms; Hazard assessment; Storm surges; Numerical simulations; Historical account; Reviews; Simulation; coastal hazards; USA, Louisiana, New Orleans DO - http://dx.doi.org/10.1007/s11069-009-9379-y ER - TY - JOUR T1 - Haemodynamically unstable pelvic fractures AN - 21071731; 11088926 AB - Bleeding pelvic fractures that result in haemodynamic instability have a reported mortality rate as high as 40%. Because of the extreme force needed to disrupt the pelvic ring, associated injuries are common and mortality is usually from uncontrolled haemorrhage from extra-pelvic sources. Identifying and controlling all sources of bleeding is a complex challenge and is best managed by a multi-disciplinary team, which include trauma surgeons, orthopaedic surgeons and interventional radiologists. Once the pelvis is identified as the major source of haemorrhage, component therapy reconstituting whole blood should be used and the pelvic region wrapped circumferentially with a sheet or pelvic binder. Patients at risk for arterial bleeding who continue to show haemodynamic instability despite resuscitative efforts should undergo immediate arteriography and embolisation of bleeding pelvic vessels. If this is unavailable or delayed, or the patient has other injuries (i.e., head, chest, intra-abdominal, long bone), external fixation and pelvic packing, performed concomitantly with other life-saving procedures, may be used to further reduce pelvic venous bleeding. If however, the patient remains haemodynamically labile without apparent source of blood loss, transcatheter angiographic embolisation should be attempted to locate and stop pelvic arterial bleeding. Institutional practice guidelines have been shown to reduce mortality and should be developed by all centres treating pelvic fractures. JF - Injury AU - White, Christopher E AU - Hsu, Joseph R AU - Holcomb, John B AD - Institute of Surgical Research, Fort Sam Houston, 3400 Rawley E. Chambers Avenue, Fort Sam Houston, TX 78234, USA, christopher.eric.white@us.army.mil Y1 - 2009/10// PY - 2009 DA - Oct 2009 SP - 1023 EP - 1030 PB - Elsevier Science, The Boulevard Kidlington Oxford OX5 1GB UK VL - 40 IS - 10 SN - 0020-1383, 0020-1383 KW - Risk Abstracts; Health & Safety Science Abstracts UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21071731?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Injury&rft.atitle=Haemodynamically+unstable+pelvic+fractures&rft.au=White%2C+Christopher+E%3BHsu%2C+Joseph+R%3BHolcomb%2C+John+B&rft.aulast=White&rft.aufirst=Christopher&rft.date=2009-10-01&rft.volume=40&rft.issue=10&rft.spage=1023&rft.isbn=&rft.btitle=&rft.title=Injury&rft.issn=00201383&rft_id=info:doi/10.1016%2Fj.injury.2008.11.023 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-11-01 N1 - Last updated - 2011-12-14 DO - http://dx.doi.org/10.1016/j.injury.2008.11.023 ER - TY - JOUR T1 - Phenotypic analysis of dengue virus isolates associated with dengue fever and dengue hemorrhagic fever for cellular attachment, replication and interferon signaling ability AN - 20797774; 10893988 AB - Eighteen dengue viruses (DENVs) representing all four serotypes, isolated from pediatric patients at children's hospital, Queen Sirikit National Institute of Child Health, Bangkok, Thailand exhibiting a diverse spectrum of disease ranging from uncomplicated dengue fever (DF) to severe dengue hemorrhagic fever (DHF), were tested for their ability to attach to host cells, replicate and interfere with the IFNa signaling pathway by interfering with signal transducer and activator of transcription 1 (STAT-1) function. Although most isolates suppressed IFNa-induced STAT-1 phosphorylation, our results showed no difference between DENV strains associated with DF and those associated with DHF. However, the DHF isolates tended replicate to higher titers in dendritic cells (DCs) than the DF isolates, but this ability was independent of their cell-binding capability. Our results suggest that the emergence early in infection of viruses with a high degree of replication fitness may play an important role in DENV pathogenesis. JF - Virus Research AU - Takhampunya, R AU - Palmer AU - McClain, S AU - Barvir, DA AU - Lynch, J AU - Jarman, R G AU - Thomas, S AU - Gibbons, R V AU - Burgess, TH AU - Sun, P AU - Kamau, E AU - Putnak, R AU - Zhang, C AD - Walter Reed Army Institute of Research, Silver Spring, MD, USA, chunlin.zhang@amedd.army.mil Y1 - 2009/10// PY - 2009 DA - October 2009 SP - 31 EP - 38 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 145 IS - 1 SN - 0168-1702, 0168-1702 KW - Immunology Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; Virology & AIDS Abstracts KW - Dengue virus KW - Fitness KW - Human diseases KW - Serotypes KW - Viruses KW - Thailand, Chacoengsao Prov., Bangkok KW - Hosts KW - Infection KW - Phenotypes KW - Public health KW - Dendritic cells KW - Phosphorylation KW - Dengue KW - a-Interferon KW - Transducers KW - Pediatrics KW - Replication KW - Transcription KW - Children KW - Queens KW - Dengue hemorrhagic fever KW - Stat1 protein KW - Hospitals KW - Signal transduction KW - Q1 08484:Species interactions: parasites and diseases KW - V 22320:Replication KW - F 06910:Microorganisms & Parasites KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20797774?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Virus+Research&rft.atitle=Phenotypic+analysis+of+dengue+virus+isolates+associated+with+dengue+fever+and+dengue+hemorrhagic+fever+for+cellular+attachment%2C+replication+and+interferon+signaling+ability&rft.au=Takhampunya%2C+R%3BPalmer%3BMcClain%2C+S%3BBarvir%2C+DA%3BLynch%2C+J%3BJarman%2C+R+G%3BThomas%2C+S%3BGibbons%2C+R+V%3BBurgess%2C+TH%3BSun%2C+P%3BKamau%2C+E%3BPutnak%2C+R%3BZhang%2C+C&rft.aulast=Takhampunya&rft.aufirst=R&rft.date=2009-10-01&rft.volume=145&rft.issue=1&rft.spage=31&rft.isbn=&rft.btitle=&rft.title=Virus+Research&rft.issn=01681702&rft_id=info:doi/10.1016%2Fj.virusres.2009.05.016 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-09-01 N1 - Last updated - 2016-10-12 N1 - SubjectsTermNotLitGenreText - Human diseases; Transducers; Replication; Viruses; Hosts; Phenotypes; Public health; Fitness; Serotypes; Pediatrics; Transcription; Children; Infection; Dendritic cells; Queens; Dengue hemorrhagic fever; Phosphorylation; Dengue; Stat1 protein; a-Interferon; Signal transduction; Hospitals; Dengue virus; Thailand, Chacoengsao Prov., Bangkok DO - http://dx.doi.org/10.1016/j.virusres.2009.05.016 ER - TY - JOUR T1 - Influence of exercise mode and osteogenic index on bone biomarker responses during short-term physical training AN - 20700443; 10853625 AB - Prescribing exercise based on intensity, frequency, and duration of loading may maximize osteogenic responses in bone, but a model of the osteogenic potential of exercise has not been established in humans. In rodents, an osteogenic index (OI) has been used to predict the osteogenic potential of exercise. The current study sought to determine whether aerobic, resistance, or combined aerobic and resistance exercise programs conducted over eight weeks and compared to a control group could produce changes in biochemical markers of bone turnover indicative of bone formation. We further sought to determine whether an OI could be calculated for each of these programs that would reflect observed biochemical changes. We collected serum biomarkers [bone-specific alkaline phosphatase (BAP), osteocalcin, tartrate-resistant acid phosphatase (TRAP), C-terminal telopeptide fragment of type I collagen (CTx), deoxypyridinoline (DPD), 25-hydroxy vitamin D (25(OH)D), and parathyroid hormone (PTH)] in 56 women (20.3+/-1.8 years) before, during and after eight weeks of training. We also measured bone mineral density (BMD) at regional areas of interest using DXA and pQCT. Biomarkers of bone formation (BAP and osteocalcin) increased in the Resistance and Combined groups (p<0.05), while biomarkers of bone resorption (TRAP and DPD) decreased and increased, respectively, after training (p<0.05) in all groups. Small changes in volumetric and areal BMD (p<0.05) were observed in the distal tibia in the Aerobic and Combined groups, respectively. Mean weekly OIs were 16.0+/-1.9, 20.6+/-2.2, and 36.9+/-5.2 for the Resistance, Aerobic, and Combined groups, respectively. The calculated osteogenic potential of our programs did not correlate with the observed changes in biomarkers of bone turnover. The results of the present study demonstrate that participation in an eight week physical training program that incorporates a resistance component by previously inactive young women results in alterations in biomarkers of bone remodeling indicative of increased formation without substantial alterations in markers of resorption. JF - Bone AU - Lester, ME AU - Urso, M L AU - Evans, R K AU - Pierce, J R AU - Spiering, BA AU - Maresh, C M AU - Hatfield, D L AU - Kraemer, W J AU - Nindl, B C AD - U.S. Army Research Institute of Environmental Medicine, Building 42, Kansas Street, Natick, MA 01760, USA, bradley.nindl@us.army.mil Y1 - 2009/10// PY - 2009 DA - Oct 2009 SP - 768 EP - 776 PB - Elsevier Science, Box 882 New York NY 10159 USA, [mailto:usinfo-f@elsevier.com] VL - 45 IS - 4 SN - 8756-3282, 8756-3282 KW - Physical Education Index; Calcium & Calcified Tissue Abstracts KW - Biochemical markers KW - Programs KW - Bones KW - Aerobics KW - Loading KW - Women KW - Dual energy X-ray absorptiometry KW - Collagen KW - Models KW - Bone mineral density KW - Vitamins KW - Training (programs) KW - Parathyroid hormone KW - Acid phosphatase (tartrate-resistant) KW - Bone resorption KW - Bone remodelling KW - deoxypyridinoline KW - Collagen (type I) KW - Osteogenesis KW - Exercise (duration) KW - Osteocalcin KW - Resistance exercise KW - biomarkers KW - Physical training KW - Tibia KW - Vitamin D KW - Alkaline phosphatase KW - Computed tomography KW - Bone turnover KW - PE 090:Sports Medicine & Exercise Sport Science KW - T 2025:Bone and Bone Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20700443?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Bone&rft.atitle=Influence+of+exercise+mode+and+osteogenic+index+on+bone+biomarker+responses+during+short-term+physical+training&rft.au=Lester%2C+ME%3BUrso%2C+M+L%3BEvans%2C+R+K%3BPierce%2C+J+R%3BSpiering%2C+BA%3BMaresh%2C+C+M%3BHatfield%2C+D+L%3BKraemer%2C+W+J%3BNindl%2C+B+C&rft.aulast=Lester&rft.aufirst=ME&rft.date=2009-10-01&rft.volume=45&rft.issue=4&rft.spage=768&rft.isbn=&rft.btitle=&rft.title=Bone&rft.issn=87563282&rft_id=info:doi/10.1016%2Fj.bone.2009.06.001 LA - English DB - Physical Education Index N1 - Date revised - 2009-09-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Programs; Bone mineral density; Bones; Exercise (duration); Aerobics; Vitamins; Training (programs); Women; Resistance exercise; Biochemical markers; Loading; Osteocalcin; Dual energy X-ray absorptiometry; biomarkers; Models; Physical training; Collagen; Tibia; Alkaline phosphatase; Vitamin D; Computed tomography; Acid phosphatase (tartrate-resistant); Parathyroid hormone; Bone resorption; Bone turnover; Bone remodelling; Collagen (type I); deoxypyridinoline; Osteogenesis DO - http://dx.doi.org/10.1016/j.bone.2009.06.001 ER - TY - CPAPER T1 - A Discretionary Access Control Method for Preventing Data Exfiltration via Removable Devices T2 - International Conference on Digital Forensics & Cyber Crime (ICDF2C) AN - 42448047; 5417815 JF - International Conference on Digital Forensics & Cyber Crime (ICDF2C) AU - Wilson, Duane AU - Lavine, Michael Y1 - 2009/09/30/ PY - 2009 DA - 2009 Sep 30 KW - Data processing KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42448047?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=International+Conference+on+Digital+Forensics+%26+Cyber+Crime+%28ICDF2C%29&rft.atitle=A+Discretionary+Access+Control+Method+for+Preventing+Data+Exfiltration+via+Removable+Devices&rft.au=Wilson%2C+Duane%3BLavine%2C+Michael&rft.aulast=Wilson&rft.aufirst=Duane&rft.date=2009-09-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=International+Conference+on+Digital+Forensics+%26+Cyber+Crime+%28ICDF2C%29&rft.issn=&rft_id=info:doi/ L2 - http://www.d-forensics.org/program.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Military Security Operations in Afghanistan and Iraq: Part 1 T2 - 55th Annual Seminar of the American Society for Industrial Security AN - 42303118; 5340879 JF - 55th Annual Seminar of the American Society for Industrial Security AU - Kamide, Joe AU - Carruth, Timothy AU - Heugel, Doug AU - Stanford, Robert Y1 - 2009/09/21/ PY - 2009 DA - 2009 Sep 21 KW - Afghanistan KW - Iraq KW - Security KW - Military KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42303118?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=55th+Annual+Seminar+of+the+American+Society+for+Industrial+Security&rft.atitle=Military+Security+Operations+in+Afghanistan+and+Iraq%3A+Part+1&rft.au=Kamide%2C+Joe%3BCarruth%2C+Timothy%3BHeugel%2C+Doug%3BStanford%2C+Robert&rft.aulast=Kamide&rft.aufirst=Joe&rft.date=2009-09-21&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=55th+Annual+Seminar+of+the+American+Society+for+Industrial+Security&rft.issn=&rft_id=info:doi/ L2 - http://asis2009.expoplanner.com/sesearchformday.wcs LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-12-18 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Dramatic Differences in Organophosphorus Hydrolase Activity between Human and Chimeric Recombinant Mammalian Paraoxonase-1 Enzymes AN - 754540852; 13265203 AB - Human serum paraoxonase-1 (HuPON1) has the capacity to hydrolyze aryl esters, lactones, oxidized phospholipids, and organophosphorus (OP) compounds. HuPON1 and bacterially expressed chimeric recombinant PON1s (G2E6 and G3C9) differ by multiple amino acids, none of which are in the putative enzyme active site. To address the importance of these amino acid differences, the abilities of HuPON1, G2E6, G3C9, and several variants to hydrolyze phenyl acetate, paraoxon, and V-type OP nerve agents were examined. HuPON1 and G2E6 have a 10-fold greater catalytic efficiency toward phenyl acetate than G3C9. In contrast, bacterial PON1s are better able to promote hydrolysis of paraoxon, whereas HuPON1 is considerably better at catalyzing the hydrolysis of nerve agents VX and VR. These studies demonstrate that mutations distant from the active site of PON1 have large and unpredictable effects on the substrate specificities and possibly the hydrolytic mechanisms of HuPON1, G2E6, and G3C9. The replacement of residue H115 in the putative active site with tryptophan (H115W) has highly disparate effects on HuPON1 and G2E6. In HuPON1, variant H115W loses the ability to hydrolyze VR but has improved activity toward paraoxon and VX. The H115W variant of G2E6 has paraoxonase activity similar to that of wild-type G2E6, modest activity with phenyl acetate and VR, and enhanced VX hydrolysis. VR inhibits H115W HuPON1 competitively when paraoxon is the substrate and noncompetitively when VX is the substrate. We have identified the first variant of HuPON1, H115W, that displays significantly enhanced catalytic activity against an authentic V-type nerve agent. JF - Biochemistry (Washington) AU - Otto, Tamara C AU - Harsch, Christina K AU - Yeung, David T AU - Magliery, Thomas J AU - Cerasoli, Douglas M AU - Lenz, David E AD - Physiology and Immunology Branch, Research Division, U.S. Army Medical Research Institute of Chemical Defense, 3100 Ricketts Point Road, Aberdeen Proving Ground, Maryland 21010-5400 Y1 - 2009/09/18/ PY - 2009 DA - 2009 Sep 18 SP - 10416 EP - 10422 PB - American Chemical Society, P.O. Box 182426 Columbus OH 43218-2426 USA VL - 48 IS - 43 SN - 0006-2960, 0006-2960 KW - Microbiology Abstracts B: Bacteriology KW - nerve agents KW - Tryptophan KW - Amino acids KW - Substrate specificity KW - Enzymes KW - Aryldialkylphosphatase KW - lactones KW - Paraoxon KW - Esters KW - Acetic acid KW - Hydrolysis KW - hydrolase KW - VX KW - Mutation KW - Phospholipids KW - J 02330:Biochemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754540852?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Biochemistry+%28Washington%29&rft.atitle=Dramatic+Differences+in+Organophosphorus+Hydrolase+Activity+between+Human+and+Chimeric+Recombinant+Mammalian+Paraoxonase-1+Enzymes&rft.au=Otto%2C+Tamara+C%3BHarsch%2C+Christina+K%3BYeung%2C+David+T%3BMagliery%2C+Thomas+J%3BCerasoli%2C+Douglas+M%3BLenz%2C+David+E&rft.aulast=Otto&rft.aufirst=Tamara&rft.date=2009-09-18&rft.volume=48&rft.issue=43&rft.spage=10416&rft.isbn=&rft.btitle=&rft.title=Biochemistry+%28Washington%29&rft.issn=00062960&rft_id=info:doi/10.1021%2Fbi901161b L2 - http://pubs.acs.org/doi/abs/10.1021/bi901161b LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2013-10-04 N1 - SubjectsTermNotLitGenreText - nerve agents; Tryptophan; Amino acids; Aryldialkylphosphatase; Enzymes; Substrate specificity; Paraoxon; lactones; Esters; Hydrolysis; Acetic acid; hydrolase; VX; Mutation; Phospholipids DO - http://dx.doi.org/10.1021/bi901161b ER - TY - JOUR T1 - Race does not impact outcome for advanced ovarian cancer patients treated with cisplatin/paclitaxel: an analysis of Gynecologic Oncology Group trials. AN - 67647168; 19536873 AB - The objectives of this study were to confirm whether racial disparity exists with regard to outcome between black women and white women with ovarian cancer and to identify factors associated with the administration of adjuvant treatment that had an impact on survival. A retrospective review of 97 black women and 1392 white women with International Federation of Gynecology and Obstetrics stage III/IV ovarian carcinoma was performed. All patients received paclitaxel combined with cisplatin while participating in 1 of 7 Gynecologic Oncology Group clinical trials. The treatment parameters that were reviewed included relative dose, relative time, and relative dose intensity. The treatment parameters and outcomes were compared between black patients and white patients. There were no differences in relative dose (0.90 vs 0.89), relative time (1.02 vs 0.99), or relative dose intensity (0.90 vs 0.91) received between black patients and white patients. Black women had less grade 3 and 4 leukopenia (53% vs 63%; P0, age>or=70 years, and mucinous histology were associated with not completing treatment (P.05 for all). When they received similar treatment, there was no difference in clinical outcome between black women and white women with advanced stage epithelial ovarian cancer when they received similar treatment as participants in Gynecologic Oncology Group clinical trials. Black patients may experience less severe gastrointestinal toxicity or leukopenia compared with whites when treated with platinum-based chemotherapy. JF - Cancer AU - Farley, John H AU - Tian, Chunqiao AU - Rose, G Scott AU - Brown, Carol L AU - Birrer, Michael AU - Maxwell, G Larry AD - Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20832, USA. john.farley@us.army.mil Y1 - 2009/09/15/ PY - 2009 DA - 2009 Sep 15 SP - 4210 EP - 4217 VL - 115 IS - 18 SN - 0008-543X, 0008-543X KW - Paclitaxel KW - P88XT4IS4D KW - Cisplatin KW - Q20Q21Q62J KW - Abridged Index Medicus KW - Index Medicus KW - Randomized Controlled Trials as Topic KW - Drug Administration Schedule KW - Minority Health KW - Humans KW - European Continental Ancestry Group KW - Treatment Outcome KW - Aged KW - Middle Aged KW - Female KW - Paclitaxel -- administration & dosage KW - Ovarian Neoplasms -- ethnology KW - Health Status Disparities KW - African Americans KW - Antineoplastic Combined Chemotherapy Protocols -- adverse effects KW - Antineoplastic Combined Chemotherapy Protocols -- therapeutic use KW - Ovarian Neoplasms -- drug therapy KW - Cisplatin -- administration & dosage UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67647168?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Cancer&rft.atitle=Race+does+not+impact+outcome+for+advanced+ovarian+cancer+patients+treated+with+cisplatin%2Fpaclitaxel%3A+an+analysis+of+Gynecologic+Oncology+Group+trials.&rft.au=Farley%2C+John+H%3BTian%2C+Chunqiao%3BRose%2C+G+Scott%3BBrown%2C+Carol+L%3BBirrer%2C+Michael%3BMaxwell%2C+G+Larry&rft.aulast=Farley&rft.aufirst=John&rft.date=2009-09-15&rft.volume=115&rft.issue=18&rft.spage=4210&rft.isbn=&rft.btitle=&rft.title=Cancer&rft.issn=0008543X&rft_id=info:doi/10.1002%2Fcncr.24482 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-10-08 N1 - Date created - 2009-09-10 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1002/cncr.24482 ER - TY - JOUR T1 - Weight-of-evidence evaluation in environmental assessment: review of qualitative and quantitative approaches. AN - 67583753; 19619890 AB - Assessments of human health and ecological risk draw upon multiple types and sources of information, requiring the integration of multiple lines of evidence before conclusions may be reached. Risk assessors often make use of weight-of-evidence (WOE) approaches to perform the integration, whether integrating evidence concerning potential carcinogenicity, toxicity, and exposure from chemicals at a contaminated site, or evaluating processes concerned with habitat loss or modification when managing a natural resource. Historically, assessors have relied upon qualitative WOE approaches, such as professional judgment, or limited quantitative methods, such as direct scoring, to develop conclusions from multiple lines of evidence. Current practice often lacks transparency resulting in risk estimates lacking quantified uncertainty. This paper reviews recent applications of weight of evidence used in human health and ecological risk assessment. Applications are sorted based on whether the approach relies on qualitative and quantitative methods in order to reveal trends in the use of the term weight of evidence, especially as a means to facilitate structured and transparent development of risk conclusions from multiple lines of evidence. JF - The Science of the total environment AU - Linkov, Igor AU - Loney, Drew AU - Cormier, Susan AU - Satterstrom, F Kyle AU - Bridges, Todd AD - US Army Engineer Research and Development Center, Vicksburg, MS 39180, United States. Igor.Linkov@usace.army.mil Y1 - 2009/09/15/ PY - 2009 DA - 2009 Sep 15 SP - 5199 EP - 5205 VL - 407 IS - 19 KW - Index Medicus KW - Humans KW - Health Status KW - Risk Assessment -- methods KW - Decision Support Techniques KW - Ecotoxicology KW - Environmental Medicine -- methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67583753?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Science+of+the+total+environment&rft.atitle=Weight-of-evidence+evaluation+in+environmental+assessment%3A+review+of+qualitative+and+quantitative+approaches.&rft.au=Linkov%2C+Igor%3BLoney%2C+Drew%3BCormier%2C+Susan%3BSatterstrom%2C+F+Kyle%3BBridges%2C+Todd&rft.aulast=Linkov&rft.aufirst=Igor&rft.date=2009-09-15&rft.volume=407&rft.issue=19&rft.spage=5199&rft.isbn=&rft.btitle=&rft.title=The+Science+of+the+total+environment&rft.issn=1879-1026&rft_id=info:doi/10.1016%2Fj.scitotenv.2009.05.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-09-30 N1 - Date created - 2009-08-11 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.scitotenv.2009.05.004 ER - TY - JOUR T1 - Mobility and sorption of bis-2-chloroethyl ether in an aquifer material. AN - 67428028; 19345490 AB - Active treatment of BCEE (bis-2-chloroethyl ether) is being currently performed in the on-site Cohansey Aquifer at the Lipari Superfund Site. Remediation of BCEE in the underlying Kirkwood aquifer is being considered, necessitating investigations of BCEE geochemistry in aquifer material from the site. It is currently unknown to what extent BCEE is present in the dissolved, sorbed, or free-product phase in the Kirkwood Sand aquifer material. A series of partition coefficient sorption, column leach, and column loading tests were conducted to determine BCEE sorption to, and mobility in, the Kirkwood Sand aquifer material. The leach studies indicated that up to 50% of BCEE spiked (as free-phase product) onto two aquifer material column designs could be leached in approximately 18h, due to the high aqueous solubility of BCEE. Dissolved BCEE concentrations then began to plateau as sorption reactions hindered further leaching, resulting in up to 80% removal after 48h. Column loading and batch sorption experiments suggest that BCEE mobility is limited by sorption rather than solubility factors. Tracer tests in both column loading and batch sorption tests indicate sorption hinders leaching of BCEE from the Kirkwood Sand material. JF - Journal of hazardous materials AU - Bednar, A J AU - Kirgan, R A AU - Karn, R A AU - Donovan, B AU - Mohn, M F AU - Sirkis, D M AD - US Army Engineer Research and Development Center, Environmental Laboratory, Vicksburg, MS 39180, United States. Anthony.J.Bednar@usace.army.mil Y1 - 2009/09/15/ PY - 2009 DA - 2009 Sep 15 SP - 1041 EP - 1046 VL - 168 IS - 2-3 KW - Ethers KW - 0 KW - Water Pollutants, Chemical KW - Ethylene Chlorohydrin KW - 753N66IHAN KW - Index Medicus KW - United States KW - Mass Spectrometry KW - United States Environmental Protection Agency KW - Chromatography, Gas KW - Water Pollutants, Chemical -- chemistry KW - Ethers -- chemistry KW - Ethylene Chlorohydrin -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67428028?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+hazardous+materials&rft.atitle=Mobility+and+sorption+of+bis-2-chloroethyl+ether+in+an+aquifer+material.&rft.au=Bednar%2C+A+J%3BKirgan%2C+R+A%3BKarn%2C+R+A%3BDonovan%2C+B%3BMohn%2C+M+F%3BSirkis%2C+D+M&rft.aulast=Bednar&rft.aufirst=A&rft.date=2009-09-15&rft.volume=168&rft.issue=2-3&rft.spage=1041&rft.isbn=&rft.btitle=&rft.title=Journal+of+hazardous+materials&rft.issn=1873-3336&rft_id=info:doi/10.1016%2Fj.jhazmat.2009.02.138 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-09-11 N1 - Date created - 2009-06-29 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.jhazmat.2009.02.138 ER - TY - JOUR T1 - Post-exposure treatment with nasal atropine methyl bromide protects against microinstillation inhalation exposure to sarin in guinea pigs AN - 20703250; 10851947 AB - We evaluated the protective efficacy of nasal atropine methyl bromide (AMB) which does not cross the blood-brain barrier against sarin inhalation exposure. Age and weight matched male guinea pigs were exposed to 846.5 mg/m super(3) sarin using a microinstillation inhalation exposure technique for 4 min. The survival rate at this dose was 20%. Post-exposure treatment with nasal AMB (2.5 mg/kg, 1 min) completely protected against sarin induced toxicity (100% survival). Development of muscular tremors was decreased in animals treated with nasal AMB. Post-exposure treatment with nasal AMB also normalized acute decrease in blood oxygen saturation and heart rate following sarin exposure. Inhibition of blood AChE and BChE activities following sarin exposure was reduced in animals treated with nasal AMB, indicating that survival increases the metabolism of sarin or expression of AChE. The body weight loss of animals exposed to sarin and treated with nasal AMB was similar to saline controls. No differences were observed in lung accessory lobe or tracheal edema following exposure to sarin and subsequent treatment with nasal AMB. Total bronchoalveolar lavage fluid (BALF) protein, a biomarker of lung injury, showed trends similar to saline controls. Surfactant levels post-exposure treatment with nasal AMB returned to normal, similar to saline controls. Alkaline phosphatase levels post-exposure treatment with nasal AMB were decreased. Taken together, these data suggest that nasal AMB blocks the copious airway secretion and peripheral cholinergic effects and protects against lethal inhalation exposure to sarin thus increasing survival. JF - Toxicology and Applied Pharmacology AU - Che, M M AU - Conti, M AU - Chanda, S AU - Boylan, M AU - Sabnekar, P AU - Rezk, P AU - Amari, E AU - Sciuto, A M AU - Gordon, R K AU - Doctor, B P AU - Nambiar, M P AD - Division of Biochemistry, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910-7500, USA, Madhusoodana.nambiar@amedd.army.mil Y1 - 2009/09/15/ PY - 2009 DA - 2009 Sep 15 SP - 251 EP - 257 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 239 IS - 3 SN - 0041-008X, 0041-008X KW - Environment Abstracts; Toxicology Abstracts KW - Inhalation KW - Injuries KW - Blood-brain barrier KW - Secretion KW - Heart rate KW - Survival KW - Edema KW - Bronchus KW - heart rate KW - Sarin KW - Methyl bromide KW - tremor KW - body weight KW - Respiratory tract KW - Bioindicators KW - Data processing KW - Toxicity KW - biomarkers KW - Alveoli KW - Body weight loss KW - Oxygen KW - Alkaline phosphatase KW - Lung KW - survival KW - Surfactants KW - Metabolism KW - Atropine KW - X 24310:Pharmaceuticals KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20703250?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+and+Applied+Pharmacology&rft.atitle=Post-exposure+treatment+with+nasal+atropine+methyl+bromide+protects+against+microinstillation+inhalation+exposure+to+sarin+in+guinea+pigs&rft.au=Che%2C+M+M%3BConti%2C+M%3BChanda%2C+S%3BBoylan%2C+M%3BSabnekar%2C+P%3BRezk%2C+P%3BAmari%2C+E%3BSciuto%2C+A+M%3BGordon%2C+R+K%3BDoctor%2C+B+P%3BNambiar%2C+M+P&rft.aulast=Che&rft.aufirst=M&rft.date=2009-09-15&rft.volume=239&rft.issue=3&rft.spage=251&rft.isbn=&rft.btitle=&rft.title=Toxicology+and+Applied+Pharmacology&rft.issn=0041008X&rft_id=info:doi/10.1016%2Fj.taap.2009.06.002 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-09-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Inhalation; Data processing; Injuries; Blood-brain barrier; Secretion; Heart rate; Edema; Survival; Toxicity; biomarkers; Alveoli; Body weight loss; Oxygen; Alkaline phosphatase; Bronchus; Lung; Sarin; Methyl bromide; tremor; Surfactants; Metabolism; Atropine; Respiratory tract; Bioindicators; heart rate; survival; body weight DO - http://dx.doi.org/10.1016/j.taap.2009.06.002 ER - TY - CPAPER T1 - Command Culture and the US Army in Iraq: Evidence of Disparate Cultures and Approaches to Counterinsurgency T2 - 105th Annual Meeting of the American Political Science Association AN - 42414336; 5391979 JF - 105th Annual Meeting of the American Political Science Association AU - Zais, Matthew Y1 - 2009/09/03/ PY - 2009 DA - 2009 Sep 03 KW - Iraq KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42414336?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=105th+Annual+Meeting+of+the+American+Political+Science+Association&rft.atitle=Command+Culture+and+the+US+Army+in+Iraq%3A+Evidence+of+Disparate+Cultures+and+Approaches+to+Counterinsurgency&rft.au=Zais%2C+Matthew&rft.aulast=Zais&rft.aufirst=Matthew&rft.date=2009-09-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=105th+Annual+Meeting+of+the+American+Political+Science+Association&rft.issn=&rft_id=info:doi/ L2 - http://www.apsanet.org/_pdf/2009program.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - The Crafting of National Security Policy in the 21st Century T2 - 105th Annual Meeting of the American Political Science Association AN - 42405104; 5391156 JF - 105th Annual Meeting of the American Political Science Association AU - Stolberg, Alan Y1 - 2009/09/03/ PY - 2009 DA - 2009 Sep 03 KW - Security KW - Policies KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42405104?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=105th+Annual+Meeting+of+the+American+Political+Science+Association&rft.atitle=The+Crafting+of+National+Security+Policy+in+the+21st+Century&rft.au=Stolberg%2C+Alan&rft.aulast=Stolberg&rft.aufirst=Alan&rft.date=2009-09-03&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=105th+Annual+Meeting+of+the+American+Political+Science+Association&rft.issn=&rft_id=info:doi/ L2 - http://www.apsanet.org/_pdf/2009program.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-06 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Infrared radiative transfer model for aerosol clouds: implications to remote sensing by ground-based and airborne sensors AN - 907930476; 11785318 AB - It is of vital interest to understand how cloud particles interact with ambient atmospheric radiation fields. We developed a comprehensive analytical radiative transfer model for passive infrared remote sensing applicable to ground-based and airborne sensors. We show the qualitative difference between simple non-scattering aerosols (pseudo vapor cloud) and an aerosol cloud where scattering, absorption and emission occur. Simulations revealed two interesting observations: aerosol cloud detection from an airborne platform may be more challenging than for a ground-based sensor, and the detection of an aerosol cloud in emission mode is different from the detection of an aerosol cloud in absorption mode. JF - Proceedings of SPIE - The International Society for Optical Engineering AU - Ben-David, Avishai AU - Davidson, Charles E AD - U.S. Army Edgewood Chemical Biological Ctr. (USA) Y1 - 2009/09// PY - 2009 DA - Sep 2009 PB - SPIE, P.O. BOX 10 Bellingham WA 98227-0010 USA VL - 7475 SN - 0277-786X, 0277-786X KW - Environment Abstracts; Meteorological & Geoastrophysical Abstracts KW - Article no. 74750F KW - Aerosols KW - Sensors KW - Remote sensing KW - Simulation KW - Aerosol clouds KW - Particulates KW - Clouds KW - Radiative transfer models KW - Remote sensing of clouds KW - Cloud particles KW - Numerical simulations KW - Emissions KW - Absorption KW - Radiative transfer KW - radiative transfer KW - Atmospheric radiation KW - M2 551.510.42:Air Pollution (551.510.42) KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/907930476?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=Proceedings+of+SPIE+-+The+International+Society+for+Optical+Engineering&rft.atitle=Infrared+radiative+transfer+model+for+aerosol+clouds%3A+implications+to+remote+sensing+by+ground-based+and+airborne+sensors&rft.au=Ben-David%2C+Avishai%3BDavidson%2C+Charles+E&rft.aulast=Ben-David&rft.aufirst=Avishai&rft.date=2009-09-01&rft.volume=7475&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Proceedings+of+SPIE+-+The+International+Society+for+Optical+Engineering&rft.issn=0277786X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-12-01 N1 - SuppNotes - Session: Radiative Transfer N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Clouds; Radiative transfer models; Remote sensing of clouds; Cloud particles; Numerical simulations; Remote sensing; Aerosol clouds; Radiative transfer; Atmospheric radiation; Aerosols; Sensors; Absorption; Emissions; Simulation; Particulates; radiative transfer ER - TY - JOUR T1 - Evaluation of nine oximes on in vivo reactivation of blood, brain, and tissue cholinesterase activity inhibited by organophosphorus nerve agents at lethal dose AN - 874189168; 14972611 AB - The capability of several oximes (HI-6, HLoe7, MMB-4, TMB-4, carboxime, ICD 585, ICD 692, ICD 3805, and 2-PAM) to reactivate in vivo AChE inhibited by the nerve agents sarin, cyclosarin, VX, or VR in blood, brain regions, and peripheral tissues in guinea pigs was examined and compared. Animals were injected subcutaneously with 1.0 LD sub(50) of sarin, cyclosarin, VR, or VX, and treated intramuscularly 5 min later with one of these compounds. Toxic signs and lethality were monitored, and tissue AChE activities were determined at 60 min after nerve agent. The animals exposed to sarin or cyclosarin, alone or with non-oxime treatment, some died within 60 min; however, when treated with an oxime, no animal died. For VR or VX, all animals survived for 60 min after exposure, with or without non-oxime or oxime therapy. These nerve agents caused differential degrees of inhibition: in whole blood sarin = cyclosarin > VR = VX; in brain regions sarin > cyclosarin > VX > VR; and in peripheral tissues sarin > VX > cyclosarin > VR. These oximes exhibited differential potency in reactivating nerve agent-inhibited AChE in various peripheral tissues, but not AChE activity in the brain regions. There was no difference in the AChE reactivating potency between the dichloride and dimethanesulfonate salts of HI-6. AChE inhibited by sarin was the most and cyclosarin the least susceptible to oxime reactivation. Overall, MMB-4 appeared to be, among all oximes tested, the most effective in vivo AChE reactivator against the broadest spectrum of nerve agents. JF - Toxicology Mechanisms and Methods AU - Shih, T-M AU - Skovira, J W AU - O'Donnell, J C AU - McDonough, J H AD - US Army Medical Research Institute of Chemical Defense, ATTN: MCMR-CDR-P (Dr. T.-M. Shih), 3100 Ricketts Point Road, Aberdeen Proving Ground, MD 21010-5400, USA, tsungming.a.shih@us.army.mil Y1 - 2009/09// PY - 2009 DA - Sep 2009 SP - 386 EP - 400 VL - 19 IS - 6-7 SN - 1537-6516, 1537-6516 KW - CSA Neurosciences Abstracts; Environment Abstracts; Toxicology Abstracts KW - nerve agents KW - Tissues KW - Brain KW - Cholinesterase KW - Blood KW - Salts KW - HI-6 KW - Lethality KW - oximes KW - Sarin KW - VX KW - Lethal dose KW - N3 11028:Neuropharmacology & toxicology KW - X 24300:Methods KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/874189168?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+Mechanisms+and+Methods&rft.atitle=Evaluation+of+nine+oximes+on+in+vivo+reactivation+of+blood%2C+brain%2C+and+tissue+cholinesterase+activity+inhibited+by+organophosphorus+nerve+agents+at+lethal+dose&rft.au=Shih%2C+T-M%3BSkovira%2C+J+W%3BO%27Donnell%2C+J+C%3BMcDonough%2C+J+H&rft.aulast=Shih&rft.aufirst=T-M&rft.date=2009-09-01&rft.volume=19&rft.issue=6-7&rft.spage=386&rft.isbn=&rft.btitle=&rft.title=Toxicology+Mechanisms+and+Methods&rft.issn=15376516&rft_id=info:doi/10.1080%2F15376510903213892 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-06-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - nerve agents; Salts; Blood; HI-6; Lethality; oximes; Brain; Sarin; VX; Cholinesterase; Lethal dose; Tissues DO - http://dx.doi.org/10.1080/15376510903213892 ER - TY - JOUR T1 - In vivo oxime administration does not influence Ellman acetylcholinesterase assay results AN - 874189166; 14972610 AB - Organophosphorus compounds (OPs) are potent inhibitors of acetylcholinesterase (AChE). Treatment for OP poisoning is by administration of atropine sulfate, an oxime, and diazepam. Oximes such as 2-PAM are used to reactivate OP-inhibited AChE so as to restore normal enzymatic function and serve as a true antidote. There are reports of non-enzymatic hydrolysis by oximes of acetylthiocholine in in vitro preparations in the widely used Ellman assay for AChE activity, which may confound the interpretation of AChE activity by producing elevated results. The purpose of this experiment was to determine if there is appreciable interference by therapeutic levels of oximes on the results of the Ellman assay in assessing AChE reactivation by oxime compounds in vivo. When therapeutic doses of oximes (2-PAM, HI-6, MMB-4, or MINA) were administered intramuscularly to guinea pigs and samples collected 60 min later, there was no statistical difference between oxime and saline control groups in measured AChE activity in various tissue samples, including blood. With appropriate dilution of samples prior to spectrophotometric assay, the Ellman assay is an acceptable method to measure in vivo oxime reactivation of inhibited AChE. Inclusion of an oxime control group to insure that this particular type of interference is not causing false readings in the assay is a prudent step. JF - Toxicology Mechanisms and Methods AU - Guarisco, JA AU - O'Donnell, J C AU - Skovira, J W AU - McDonough, J H AU - Shih, T-M AD - US Army Medical Research Institute of Chemical Defense, ATTN: MCMR-CDR-P (Dr T.-M. Shih), 3100 Ricketts Point Road, Aberdeen Proving Ground, MD 21010-5400, USA, tsungming.a.shih@us.army.mil Y1 - 2009/09// PY - 2009 DA - Sep 2009 SP - 379 EP - 385 VL - 19 IS - 6-7 SN - 1537-6516, 1537-6516 KW - Toxicology Abstracts KW - Statistics KW - Organophosphorus compounds KW - Acetylcholinesterase KW - Diazepam KW - Poisoning KW - Hydrolysis KW - Recovery of function KW - Sulfate KW - Blood KW - HI-6 KW - oximes KW - Language KW - Spectrophotometry KW - Antidotes KW - Atropine KW - X 24310:Pharmaceuticals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/874189166?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology+Mechanisms+and+Methods&rft.atitle=In+vivo+oxime+administration+does+not+influence+Ellman+acetylcholinesterase+assay+results&rft.au=Guarisco%2C+JA%3BO%27Donnell%2C+J+C%3BSkovira%2C+J+W%3BMcDonough%2C+J+H%3BShih%2C+T-M&rft.aulast=Guarisco&rft.aufirst=JA&rft.date=2009-09-01&rft.volume=19&rft.issue=6-7&rft.spage=379&rft.isbn=&rft.btitle=&rft.title=Toxicology+Mechanisms+and+Methods&rft.issn=15376516&rft_id=info:doi/10.1080%2F15376510903234773 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-06-01 N1 - Last updated - 2012-04-06 N1 - SubjectsTermNotLitGenreText - Organophosphorus compounds; Statistics; Acetylcholinesterase; Diazepam; Poisoning; Recovery of function; Hydrolysis; Sulfate; Blood; HI-6; oximes; Spectrophotometry; Language; Atropine; Antidotes DO - http://dx.doi.org/10.1080/15376510903234773 ER - TY - JOUR T1 - Traumatic Brain Injury and Vestibular Pathology as a Comorbidity After Blast Exposure AN - 860385779; 14539689 AB - Blasts or explosions are the most common mechanisms of injury in modern warfare. Traumatic brain injury (TBI) is a frequent consequence of exposure to such attacks. Although the management of orthopedic, integumentary, neurocognitive, and neurobehavioral sequelae in survivors of blasts has been described in the literature, less attention has been paid to the physical therapist examination and care of people with dizziness and blast-induced TBI (BITBI). Dizziness is a common clinical finding in people with BITBI; however, many US military service members who have been exposed to blasts and who are returning from Iraq and Afghanistan also complain of vertigo, gaze instability, motion intolerance, and other symptoms consistent with peripheral vestibular pathology. To date, few studies have addressed such "vestibular" complaints in service members injured by blasts. Given the demonstrated efficacy of treating the signs and symptoms associated with vestibular pathology, vestibular rehabilitation may have important implications for the successful care of service members who have been injured by blasts and who are complaining of vertigo or other symptoms consistent with vestibular pathology. In addition, there is a great need to build consensus on the clinical best practices for the assessment and management of BITBI and blast-related dizziness. The purpose of this review is to summarize the findings of clinicians and scientists conducting research on the effects of blasts with the aims of defining the scope of the problem, describing and characterizing the effects of blasts, reviewing relevant patients' characteristics and sensorimotor deficits associated with BITBI, and suggesting clinical best practices for the rehabilitation of BITBI and blast-related dizziness. JF - Physical Therapy AU - Scherer, M R AU - Schubert, M C AD - Department of Physical Therapy and Rehabilitation Science, University of Maryland School of Medicine, 100 Penn St, Baltimore, MD 21201 (USA), matthew.scherer@us.army.mil Y1 - 2009/09// PY - 2009 DA - Sep 2009 SP - 980 EP - 992 VL - 89 IS - 9 SN - 0031-9023, 0031-9023 KW - Physical Education Index KW - Evaluation KW - Management KW - Injuries KW - Rehabilitation KW - Objectives KW - Orthopedics KW - Brain KW - Military KW - Self efficacy KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/860385779?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Physical+Therapy&rft.atitle=Traumatic+Brain+Injury+and+Vestibular+Pathology+as+a+Comorbidity+After+Blast+Exposure&rft.au=Scherer%2C+M+R%3BSchubert%2C+M+C&rft.aulast=Scherer&rft.aufirst=M&rft.date=2009-09-01&rft.volume=89&rft.issue=9&rft.spage=980&rft.isbn=&rft.btitle=&rft.title=Physical+Therapy&rft.issn=00319023&rft_id=info:doi/ LA - English DB - Physical Education Index N1 - Date revised - 2011-04-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Evaluation; Management; Rehabilitation; Injuries; Objectives; Orthopedics; Brain; Military; Self efficacy ER - TY - JOUR T1 - Geochemistry of Surficial Sediments from Lake Pontchartrain Resulting from the 1997 Opening of the Bonnet Carre Spillway AN - 839689731; 14078616 AB - The Bonnet Carre Spillway is a flood-control structure that diverts Mississippi River water into Lake Pontchartrain during exceptionally high river stages. Because of elevated water levels in the Mississippi River in the spring of 1997, the Bonnet Carre Spillway was opened on March 17 and fully closed on April 18. The total volume of water discharged into Lake Pontchartrain was approximately 11.8 km3, or two times the volume of the lake, and the total mass of sediment discharged into the lake was approximately 7.1 108 kg (780,000 US tons). In 1996, 757 surface sediment samples were collected in Lake Pontchartrain and were analyzed by x-ray fluorescence spectroscopy for major cation constituents. These same sites were revisited following the 1997 Mississippi River discharge event. Analysis of the 1996 and 1997 lake-bed sediment samples was accomplished utilizing fundamental statistical and graphical methods. Element concentration contour maps and variograms for the major cations illustrate meaningful differences between the pre- and postspillway sediment samples that are not readily apparent in the analysis of the descriptive statistics alone. Major cations exhibited significantly greater spatial continuity in the postspillway samples relative to the preceding year. The concentrations of aluminum and silicon in the postspillway sediments are considered to reflect, respectively, relative variations in clay and silt contribution to total sediment. The higher concentrations of magnesium in samples collected prior to the river diversion represent adsorption of magnesium onto exchange sites in surface sediments due to exposure to more saline waters. JF - Journal of Coastal Research AU - Waters, Jeffrey P AU - Easley, Dale H AU - Noakes, Scott E AU - Penland, Shea AD - Coastal & Hydraulics Laboratory, U.S. Army Engineer Research & Development Center, 3909 Halls Ferry Road, Vicksburg, MS 39180, U.S.A., Jeffrey.p.waters@usace.army.mil Y1 - 2009/09// PY - 2009 DA - September 2009 SP - 127 EP - 140 PB - Coastal Education and Research Foundation IS - 10054 SN - 0749-0208, 0749-0208 KW - Meteorological & Geoastrophysical Abstracts; Water Resources Abstracts; ASFA 2: Ocean Technology Policy & Non-Living Resources KW - Major cations KW - aluminum KW - silicon KW - potassium KW - calcium KW - iron KW - magnesium KW - sulfur KW - geostatistics KW - variogram KW - river diversion KW - Silicon KW - Fluvial Sediments KW - Spillways KW - Fluorescence spectroscopy KW - Statistical analysis KW - Coastal research KW - Freshwater KW - Spectroscopy KW - Lakes KW - Saline water KW - River Flow KW - Rivers KW - Sediment chemistry KW - River stages KW - Geochemistry KW - River discharge KW - Silt KW - Graphical methods KW - North America, Mississippi R. KW - ASW, USA, Louisiana, Pontchartrain L. KW - Cations KW - Aluminum KW - Aluminium KW - Magnesium KW - SW 3040:Wastewater treatment processes KW - Q2 09182:Methods and instruments KW - M2 556.16:Runoff (556.16) UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/839689731?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Awaterresources&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Coastal+Research&rft.atitle=Geochemistry+of+Surficial+Sediments+from+Lake+Pontchartrain+Resulting+from+the+1997+Opening+of+the+Bonnet+Carre+Spillway&rft.au=Waters%2C+Jeffrey+P%3BEasley%2C+Dale+H%3BNoakes%2C+Scott+E%3BPenland%2C+Shea&rft.aulast=Waters&rft.aufirst=Jeffrey&rft.date=2009-09-01&rft.volume=&rft.issue=10054&rft.spage=127&rft.isbn=&rft.btitle=&rft.title=Journal+of+Coastal+Research&rft.issn=07490208&rft_id=info:doi/10.2112%2FSI54-010.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-01-01 N1 - Number of references - 13 N1 - Last updated - 2016-04-29 N1 - SubjectsTermNotLitGenreText - Sediment chemistry; Silicon; Geochemistry; Fluorescence spectroscopy; Aluminium; River discharge; Silt; Saline water; Magnesium; Graphical methods; River stages; Coastal research; Statistical analysis; Spectroscopy; Rivers; Lakes; Cations; Fluvial Sediments; Aluminum; Spillways; River Flow; North America, Mississippi R.; ASW, USA, Louisiana, Pontchartrain L.; Freshwater DO - http://dx.doi.org/10.2112/SI54-010.1 ER - TY - JOUR T1 - Measurement of trace explosive residues in a surrogate operational environment: implications for tactical use of chemical sensing in C-IED operations AN - 753633756; 13324043 AB - A campaign to measure the amount of trace explosive residues in an operational military environment was conducted on May 27--31, 2007, at the National Training Center at Fort Irwin, CA, USA. The objectives of this campaign were to develop the methods needed to collect and analyze samples from tactical military settings, to use the data obtained to determine what the trace explosive signatures suggest about the potential capabilities of chemical-based means to detect IEDs, and, finally, to present a framework whereby a sound understanding of the signature science can be used to guide development of new sensing technologies and sensor concepts of operation. Through our use of combined background and threat signature data, we have performed statistical analyses to estimate upper limits of notional sensor performance that is limited only by the spatial correlation of the signature chemicals to the threats of interest. JF - Analytical and Bioanalytical Chemistry AU - Kunz, Roderick R AU - Gregory, Kerin Clow AU - Hardy, Dennis AU - Oyler, Jonathan AU - Ostazeski, Stanley A AU - Fountain III, Augustus Way AD - Lincoln Laboratory, Massachusetts Institute of Technology, Lexington, MA 02420, USA, augustus.w.fountain@us.army.mil PY - 2009 SP - 357 EP - 369 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 395 IS - 2 SN - 1618-2642, 1618-2642 KW - Aqualine Abstracts; Water Resources Abstracts KW - USA KW - Sensors KW - Training KW - Statistical Analysis KW - Sounds KW - Explosives KW - AQ 00001:Water Resources and Supplies KW - SW 7010:Education - extramural UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/753633756?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytical+and+Bioanalytical+Chemistry&rft.atitle=Measurement+of+trace+explosive+residues+in+a+surrogate+operational+environment%3A+implications+for+tactical+use+of+chemical+sensing+in+C-IED+operations&rft.au=Kunz%2C+Roderick+R%3BGregory%2C+Kerin+Clow%3BHardy%2C+Dennis%3BOyler%2C+Jonathan%3BOstazeski%2C+Stanley+A%3BFountain+III%2C+Augustus+Way&rft.aulast=Kunz&rft.aufirst=Roderick&rft.date=2009-09-01&rft.volume=395&rft.issue=2&rft.spage=357&rft.isbn=&rft.btitle=&rft.title=Analytical+and+Bioanalytical+Chemistry&rft.issn=16182642&rft_id=info:doi/10.1007%2Fs00216-009-2748-2 L2 - http://www.springerlink.com/content/d7147414wg47561x/?p=b4db8e81ab7d4474b1a06ca2b2885c10&pi=12 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2015-12-01 N1 - Last updated - 2016-01-21 N1 - SubjectsTermNotLitGenreText - Sensors; Training; Statistical Analysis; Sounds; Explosives; USA DO - http://dx.doi.org/10.1007/s00216-009-2748-2 ER - TY - JOUR T1 - Incidence of Glenohumeral Instability in Collegiate Athletics AN - 745974720; 12609239 AB - Background: Glenohumeral instability is a common injury sustained by young athletes. Surprisingly, little is known regarding the incidence of glenohumeral instability in collegiate athletes or the relevant risk factors for injury. A better understanding of the populations most at risk may be used to develop preventive strategies.Hypothesis: The incidence of glenohumeral instability in collegiate athletics is high, and it is affected by sex, sport, type of event, and mechanism of injury.Study Design: Descriptive epidemiologic study.Methods: The National Collegiate Athletic Association injury database was queried for all glenohumeral instability events occurring between the years 1989 and 2004. An analysis of the injuries was performed by sport, activity (competition versus practice), sex, type of event (primary versus recurrent), mechanism of injury, and time loss from athletic performance. Incidence rates and incidence rate ratios were calculated.Results: A total of 4080 glenohumeral instability events were documented for an incidence rate of 0.12 injuries per 1000 athlete exposures. The sport with the greatest injury rate was men's spring football, with 0.40 injuries per 1000 athlete exposures. Overall, athletes sustained more glenohumeral instability events during games than practices (incidence rate ratio [IRR], 3.50; 95% confidence interval [CI], 3.29-3.73). Male athletes sustained more injuries than did female athletes (IRR, 2.67; 95% CI, 2.43-2.93). Female athletes were more likely to sustain an instability event as the result of contact with an object (IRR, 2.43; 95% CI, 2.08-2.84), whereas male athletes were more likely to sustain an event from player contact (IRR, 2.74; 95% CI, 2.31-3.25). Time lost to sport (>10 days) occurred in 45% of glenohumeral instability events.Conclusion: Glenohumeral instability is a relatively common injury sustained by collegiate athletes. More injuries occurred during competition and among male athletes. JF - American Journal of Sports Medicine AU - Owens, Brett D AU - Agel, Julie AU - Mountcastle, Sally B AU - Cameron, Kenneth L AU - Nelson, Bradley J AD - Division of Orthopaedic Surgery, William Beaumont Army Medical Center, El Paso, Texas, b.owens@us.army.mil Y1 - 2009/09// PY - 2009 DA - Sep 2009 SP - 1750 EP - 1754 PB - Sage Publications Ltd., 6 Bonhill St. London EC2A 4PU UK VL - 37 IS - 9 SN - 0363-5465, 0363-5465 KW - Health & Safety Science Abstracts; Physical Education Index; Risk Abstracts KW - Football (American KW - Athletics KW - Injuries KW - Intercollegiate sports KW - Athletes (men) KW - Sports KW - sports related injuries KW - athletes KW - Athletes (women) KW - injuries) KW - Competition KW - competition KW - Athletes KW - H 11000:Diseases/Injuries/Trauma KW - PE 090:Sports Medicine & Exercise Sport Science KW - R2 23060:Medical and environmental health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/745974720?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=American+Journal+of+Sports+Medicine&rft.atitle=Incidence+of+Glenohumeral+Instability+in+Collegiate+Athletics&rft.au=Owens%2C+Brett+D%3BAgel%2C+Julie%3BMountcastle%2C+Sally+B%3BCameron%2C+Kenneth+L%3BNelson%2C+Bradley+J&rft.aulast=Owens&rft.aufirst=Brett&rft.date=2009-09-01&rft.volume=37&rft.issue=9&rft.spage=1750&rft.isbn=&rft.btitle=&rft.title=American+Journal+of+Sports+Medicine&rft.issn=03635465&rft_id=info:doi/10.1177%2F0363546509334591 LA - English DB - Physical Education Index; ProQuest Environmental Science Collection N1 - Date revised - 2010-05-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Football (American; Athletics; Injuries; Intercollegiate sports; Athletes (women); Athletes (men); Sports; Competition; injuries); Athletes; sports related injuries; athletes; competition DO - http://dx.doi.org/10.1177/0363546509334591 ER - TY - JOUR T1 - Expect the unexpected: two cases of penetrating head and neck trauma from Operation Iraqi Freedom. AN - 742782395; pmid-19750465 AB - The protocol for treating penetrating head and neck trauma in a war zone differs from the standard protocol. Rather than first securing an airway, as is standard in civilian trauma cases, the primary emphasis is on assessing and controlling hemorrhage because it is the leading cause of morbidity and mortality in a battlefield setting. Once that has been addressed, we shift to standard advanced-trauma life-support protocols. We describe two cases we encountered at our combined medical clinic in Western Baghdad--one involving a 4-year old Iraqi child with an ammunition round lodged in her neck and one involving a 38-year-old female U.S. soldier with a round lodged in her right superolateral orbit. Both cases were transferred to combat support hospitals for further treatment after our initial assessment and treatment, and both had successful outcomes. JF - Ear, nose, & throat journal AU - Sarkar, Debjeet AU - Demma, Andrew AU - Stulz, Dean AU - Hsue, Gunther AD - 1st Cavalry Division, Riva Ridge Aid Station, United States Army, Baghdad, Iraq. debjeet.sarkar@us.army.mil Y1 - 2009/09// PY - 2009 DA - Sep 2009 SP - E19 EP - E21 VL - 88 IS - 9 SN - 0145-5613, 0145-5613 KW - Index Medicus KW - National Library of Medicine UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742782395?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Ear%2C+nose%2C+%26+throat+journal&rft.atitle=Expect+the+unexpected%3A+two+cases+of+penetrating+head+and+neck+trauma+from+Operation+Iraqi+Freedom.&rft.au=Sarkar%2C+Debjeet%3BDemma%2C+Andrew%3BStulz%2C+Dean%3BHsue%2C+Gunther&rft.aulast=Sarkar&rft.aufirst=Debjeet&rft.date=2009-09-01&rft.volume=88&rft.issue=9&rft.spage=E19&rft.isbn=&rft.btitle=&rft.title=Ear%2C+nose%2C+%26+throat+journal&rft.issn=01455613&rft_id=info:doi/ LA - English (eng) DB - ComDisDome N1 - Date revised - 2010-04-13 N1 - Last updated - 2010-09-25 ER - TY - JOUR T1 - Effects of synchronous nasal surgery on posttonsillectomy hemorrhage. AN - 742775787; pmid-19770429 AB - OBJECTIVE: To evaluate the effects of synchronous nasal surgery on the rate of posttonsillectomy hemorrhage. DESIGN: Retrospective medical record review. SETTING: Military tertiary referral center. PATIENTS: Adult patients identified in our surgical database from June 1, 2000, through September 31, 2005, who had undergone tonsillectomy or uvulopalatopharyngoplasty with tonsillectomy (UPPPT) either alone or with synchronous nasal surgery. MAIN OUTCOME MEASURES: The rate of posttonsillectomy hemorrhage was reviewed in all patients who underwent tonsillectomy or UPPPT at our medical center, and an investigation was conducted to determine whether synchronous nasal surgery altered this rate. RESULTS: A total of 1010 patients were included in this study, with a rate of posttonsillectomy hemorrhage of 5.5%. A total of 204 patients underwent synchronous nasal surgery. No significant difference was found between the hemorrhage rate in patients who underwent tonsillectomy or UPPPT alone and those who underwent synchronous nasal surgery (6.0% and 3.9%, respectively; P = .30). When these patients were further divided into those undergoing UPPPT and those undergoing synchronous nasal surgery, no significant difference in hemorrhage rate was found (6.2% and 2.0%, respectively; P = .06). CONCLUSIONS: Synchronous nasal surgery does not appear to increase the rate of postoperative hemorrhage in patients who undergo tonsillectomy alone or in those who undergo UPPPT. This information may help persuade physicians to perform synchronous surgical procedures instead of staging surgical procedures. In this regard, the patient requires only 1 anesthetic and 1 postoperative course without the risk of increased postoperative hemorrhage. JF - Archives of otolaryngology--head & neck surgery AU - Adams, Mary Theresa A AU - Wilhelm, Michael J AU - Demars, Sean M AU - Harsha, Wayne J AD - Department of Otolaryngology, Madigan Army Medical Center, Tacoma, WA 98431, USA. MaryTheresa.Adams@amedd.army.mil Y1 - 2009/09// PY - 2009 DA - Sep 2009 SP - 936 EP - 939 VL - 135 IS - 9 SN - 0886-4470, 0886-4470 KW - National Library of Medicine KW - Probability KW - Young Adult KW - Humans KW - Tonsillitis -- diagnosis KW - Retrospective Studies KW - Risk Assessment KW - Nose Diseases -- surgery KW - Adult KW - Treatment Outcome KW - Tonsillitis -- surgery KW - Adolescent KW - Male KW - Reference Values KW - Otorhinolaryngologic Surgical Procedures -- methods KW - Combined Modality Therapy KW - Nose Diseases -- diagnosis KW - Registries KW - Palate -- surgery KW - Incidence KW - Pharynx -- surgery KW - Otorhinolaryngologic Surgical Procedures -- adverse effects KW - Follow-Up Studies KW - Middle Aged KW - Uvula -- surgery KW - Female KW - Tonsillectomy -- methods KW - Postoperative Hemorrhage -- prevention & control KW - Tonsillectomy -- adverse effects KW - Postoperative Hemorrhage -- etiology KW - Postoperative Hemorrhage -- epidemiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742775787?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Archives+of+otolaryngology--head+%26+neck+surgery&rft.atitle=Effects+of+synchronous+nasal+surgery+on+posttonsillectomy+hemorrhage.&rft.au=Adams%2C+Mary+Theresa+A%3BWilhelm%2C+Michael+J%3BDemars%2C+Sean+M%3BHarsha%2C+Wayne+J&rft.aulast=Adams&rft.aufirst=Mary+Theresa&rft.date=2009-09-01&rft.volume=135&rft.issue=9&rft.spage=936&rft.isbn=&rft.btitle=&rft.title=Archives+of+otolaryngology--head+%26+neck+surgery&rft.issn=08864470&rft_id=info:doi/ LA - English (eng) DB - ComDisDome N1 - Date revised - 2010-04-13 N1 - Last updated - 2010-09-25 ER - TY - JOUR T1 - Influence of nanotube preparation in aquatic bioassays. AN - 734150477; 19388791 AB - Knowledge gaps in nanomaterial fate and toxicity currently limit the ability of risk assessments to characterize the environmental implications of nanomaterials. This problem is further complicated by the lack of standardized characterization and preparation methodologies for researchers to gain the needed information to assist risk assessors. In the present study, data were generated to determine if multiwalled nanotube (MWNT) fate and toxicity are altered by engineered surface modifications or by different dispersal methods. While dissolved organic matter was a good dispersing agent of MWNTs in water, the humic acid fraction was a more effective dispersant than the fulvic acid fraction. When stabilized in organic matter, the functional group attached to the MWNT controlled its toxicity. Underivatized MWNTs induced relatively moderate toxicity to Ceriodaphnia dubia after 96 h (25 +/- 19% survival at 26 mg/L), while hydrophilic groups (hydroxyl, carboxyl) reduced this toxicity (93 +/- 12% survival at 48 mg/L). However, other functional groups (alkyl, amine) increased toxicity (0 +/- 0% survival at <15 mg/L). In dispersal method studies, sonication of MWNTs increased fragmentation relative to magnetic stirring. The sonication treatment of MWNTs also slightly reduced the mortality of C. dubia in the water column but increased toxicity in the sediment to Leptocheirus plumulosus and Hyalella azteca. Findings in the present study indicate that nanotubes engineered for specific applications need to be managed independently and that laboratory methods to disperse and test nanotubes in bioassays need to be standardized to obtain repeatable results for comparison of materials. JF - Environmental toxicology and chemistry AU - Kennedy, Alan J AU - Gunter, Jonas C AU - Chappell, Mark A AU - Goss, Jennifer D AU - Hull, Matthew S AU - Kirgan, Robert A AU - Steevens, Jeffery A AD - US Army Engineer Research and Development Center, Environmental Laboratory, Vicksburg, Mississippi 39180, USA. alan.j.kennedy@usace.army.mil Y1 - 2009/09// PY - 2009 DA - September 2009 SP - 1930 EP - 1938 VL - 28 IS - 9 SN - 0730-7268, 0730-7268 KW - Water Pollutants, Chemical KW - 0 KW - Index Medicus KW - Animals KW - Daphnia -- drug effects KW - Geologic Sediments -- analysis KW - Biological Assay -- methods KW - Water Pollutants, Chemical -- toxicity KW - Nanotubes -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/734150477?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+toxicology+and+chemistry&rft.atitle=Influence+of+nanotube+preparation+in+aquatic+bioassays.&rft.au=Kennedy%2C+Alan+J%3BGunter%2C+Jonas+C%3BChappell%2C+Mark+A%3BGoss%2C+Jennifer+D%3BHull%2C+Matthew+S%3BKirgan%2C+Robert+A%3BSteevens%2C+Jeffery+A&rft.aulast=Kennedy&rft.aufirst=Alan&rft.date=2009-09-01&rft.volume=28&rft.issue=9&rft.spage=1930&rft.isbn=&rft.btitle=&rft.title=Environmental+toxicology+and+chemistry&rft.issn=07307268&rft_id=info:doi/10.1897%2F09-024.1 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-12-08 N1 - Date created - 2009-11-24 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1897/09-024.1 ER - TY - JOUR T1 - Critical timing, location and duration of glucocorticoid administration rescue mice from superantigen-induced shock and attenuate lung injury. AN - 734017003; 19539058 AB - Bacterial superantigens, such as staphylococcal enterotoxin B (SEB), are major virulence factors implicated in the pathogenesis of toxic shock. In this study we investigated the efficacy of glucocorticoid therapy in preventing SEB-induced lethal shock initiated through the respiratory route in mice. Dexamethasone, a potent anti-inflammatory steroid, administrated intranasally on the first day, followed by intraperitoneal doses on the subsequent 4 days, was effective in attenuating SEB-induced hypothermia, and reduction in systemic and pulmonary proinflammatory mediator release. This optimal dosing and schedule of glucocorticoid treatment mitigated lung inflammation and resulted in 100% survival in this intranasal mouse model of SEB-mediated shock. JF - International immunopharmacology AU - Krakauer, Teresa AU - Buckley, Marilyn J AU - Huzella, Louis M AU - Alves, Derron A AD - Integrated Toxicology Division, USAMRIID, Fort Detrick, MD 21702-5011, USA. teresa.krakauer@amedd.army.mil Y1 - 2009/09// PY - 2009 DA - September 2009 SP - 1168 EP - 1174 VL - 9 IS - 10 KW - Anti-Inflammatory Agents KW - 0 KW - Cytokines KW - Enterotoxins KW - enterotoxin B, staphylococcal KW - 39424-53-8 KW - Dexamethasone KW - 7S5I7G3JQL KW - Index Medicus KW - Cytokines -- blood KW - Enterotoxins -- immunology KW - Animals KW - Mice, Inbred C3H KW - Mice KW - Time Factors KW - Male KW - Drug Administration Routes KW - Shock, Septic -- pathology KW - Staphylococcus -- immunology KW - Shock, Septic -- drug therapy KW - Dexamethasone -- administration & dosage KW - Anti-Inflammatory Agents -- administration & dosage KW - Lung -- metabolism KW - Lung -- pathology KW - Lung -- immunology KW - Staphylococcal Infections -- drug therapy KW - Shock, Septic -- immunology KW - Staphylococcal Infections -- physiopathology KW - Lung -- drug effects KW - Shock, Septic -- physiopathology KW - Staphylococcal Infections -- pathology KW - Staphylococcal Infections -- immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/734017003?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+immunopharmacology&rft.atitle=Critical+timing%2C+location+and+duration+of+glucocorticoid+administration+rescue+mice+from+superantigen-induced+shock+and+attenuate+lung+injury.&rft.au=Krakauer%2C+Teresa%3BBuckley%2C+Marilyn+J%3BHuzella%2C+Louis+M%3BAlves%2C+Derron+A&rft.aulast=Krakauer&rft.aufirst=Teresa&rft.date=2009-09-01&rft.volume=9&rft.issue=10&rft.spage=1168&rft.isbn=&rft.btitle=&rft.title=International+immunopharmacology&rft.issn=1878-1705&rft_id=info:doi/10.1016%2Fj.intimp.2009.06.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-03-01 N1 - Date created - 2009-08-28 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.intimp.2009.06.004 ER - TY - JOUR T1 - A preliminary assessment of relative sensitivities to foreign red blood cell challenges in the northern bobwhite for potential evaluation of immunotoxicity. AN - 733967328; 19552520 AB - Many environmental toxins have been shown to suppress the immune system across taxa. The foreign red blood cell (RBC) challenge is an important part of a complement of tests used to assess immunocompetence in the laboratory because it can assess an individual's humoral response without impacting its health. This challenge is used commonly across species and measures antibody titers in response to an intraperitoneal, intravenous, or subcutaneous injection of foreign RBCs. Determination of the best appropriate foreign RBC challenge is therefore important when designing tests for evaluation of humoral responses. The northern bobwhite (Colinus virginianus) is a commonly used species for avian toxicity tests, however little is known about the relative sensitivities of its humoral responses to foreign erythrocytes. In this pilot study, we exposed adult quail to intravenous injections of 5% solutions of sheep, rat, rabbit, bovine, or chicken erythrocytes and performed antibody titers [hemagglutination assay for total immunoglobulin (Ig), IgG, and IgM] for primary and secondary responses. Although the bobwhites appeared to respond strongly to rat RBCs, high variability in responses were observed among individuals. Chicken RBCs elicited the poorest responses for both primary and secondary challenges. Sheep and bovine RBCs were adequate antigens for this test in bobwhites. We found that rabbit erythrocytes elicited the strongest responses with the least amount of variability between individuals. Rabbit RBCs, therefore, appear to be the ideal antigen for this test of the humoral response in this species. JF - Journal of immunotoxicology AU - Quinn, Michael J AU - McFarland, Craig A AU - LaFiandra, Emily M AU - Johnson, Mark S AD - U.S. Army Center Health Promotion and Preventive Medicine, Health Effects Research Program, Aberdeen Proving Ground, Maryland 21222, USA. michael.james.quinn@us.army.mil Y1 - 2009/09// PY - 2009 DA - September 2009 SP - 171 EP - 173 VL - 6 IS - 3 KW - Antigens, Heterophile KW - 0 KW - Immunoglobulins KW - Index Medicus KW - Sensitivity and Specificity KW - Animals KW - Injections, Intravenous KW - Reproducibility of Results KW - Pilot Projects KW - Rabbits KW - Immunization, Secondary KW - Rats KW - Cattle KW - Toxicology -- methods KW - Immunoglobulins -- blood KW - Species Specificity KW - Immunity, Humoral KW - Colinus -- immunology KW - Toxicity Tests KW - Antigens, Heterophile -- immunology KW - Hemagglutination Tests KW - Erythrocytes -- immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733967328?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+immunotoxicology&rft.atitle=A+preliminary+assessment+of+relative+sensitivities+to+foreign+red+blood+cell+challenges+in+the+northern+bobwhite+for+potential+evaluation+of+immunotoxicity.&rft.au=Quinn%2C+Michael+J%3BMcFarland%2C+Craig+A%3BLaFiandra%2C+Emily+M%3BJohnson%2C+Mark+S&rft.aulast=Quinn&rft.aufirst=Michael&rft.date=2009-09-01&rft.volume=6&rft.issue=3&rft.spage=171&rft.isbn=&rft.btitle=&rft.title=Journal+of+immunotoxicology&rft.issn=1547-6901&rft_id=info:doi/10.1080%2F15476910903023060 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-02-03 N1 - Date created - 2009-08-14 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1080/15476910903023060 ER - TY - JOUR T1 - Acute microinstillation inhalation exposure to sarin induces changes in respiratory dynamics and functions in guinea pigs. AN - 733832078; 19815847 AB - This study investigates the toxic effects of sarin on respiratory dynamics following microinstillation inhalation exposure in guinea pigs. Animals are exposed to sarin for 4 minutes, and respiratory functions are monitored at 4 hours and 24 hours by whole-body barometric plethysmography. Data show significant changes in respiratory dynamics and function following sarin exposure. An increase in respiratory frequency is observed at 4 hours post exposure compared with saline controls. Tidal volume and minute volume are also increased in sarin-exposed animals 4 hours after exposure. Peak inspiratory flow increases, whereas peak expiratory flow increases at 4 hours and is erratic following sarin exposure. Animals exposed to sarin show a significant decrease in expiratory time and inspiratory time. End-inspiratory pause is unchanged whereas end-expiratory pause is slightly decreased 24 hours after sarin exposure. These results indicate that inhalation exposure to sarin alters respiratory dynamics and function at 4 hours, with return to normal levels at 24 hours post exposure. JF - International journal of toxicology AU - Conti, Michele L AU - Che, Magnus M AU - Boylan, Megan AU - Sciuto, Alfred M AU - Gordon, Richard K AU - Nambiar, Madhusoodana P AD - United States Army Medical Research Institute of Chemical Defense, Edgewood, MD, USA. PY - 2009 SP - 436 EP - 447 VL - 28 IS - 5 KW - Chemical Warfare Agents KW - 0 KW - Sarin KW - B4XG72QGFM KW - Acetylcholinesterase KW - EC 3.1.1.7 KW - Oxygen KW - S88TT14065 KW - Index Medicus KW - Animals KW - Guinea Pigs KW - Oxygen -- blood KW - Plethysmography, Whole Body KW - Body Weight -- drug effects KW - Lethal Dose 50 KW - Acetylcholinesterase -- blood KW - Male KW - Organ Size -- drug effects KW - Pulmonary Edema -- blood KW - Respiratory Physiological Phenomena -- drug effects KW - Pulmonary Edema -- chemically induced KW - Lung -- drug effects KW - Sarin -- toxicity KW - Lung -- pathology KW - Pulmonary Edema -- pathology KW - Chemical Warfare Agents -- toxicity KW - Inhalation Exposure -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/733832078?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=International+journal+of+toxicology&rft.atitle=Acute+microinstillation+inhalation+exposure+to+sarin+induces+changes+in+respiratory+dynamics+and+functions+in+guinea+pigs.&rft.au=Conti%2C+Michele+L%3BChe%2C+Magnus+M%3BBoylan%2C+Megan%3BSciuto%2C+Alfred+M%3BGordon%2C+Richard+K%3BNambiar%2C+Madhusoodana+P&rft.aulast=Conti&rft.aufirst=Michele&rft.date=2009-09-01&rft.volume=28&rft.issue=5&rft.spage=436&rft.isbn=&rft.btitle=&rft.title=International+journal+of+toxicology&rft.issn=1092-874X&rft_id=info:doi/10.1177%2F1091581809344879 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-03-30 N1 - Date created - 2009-10-09 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1177/1091581809344879 ER - TY - JOUR T1 - Pain and discomfort in deployed helicopter aviators wearing body armor. AN - 67645411; 19750878 AB - In early 2007, U.S. Army helicopter aviators deployed to Afghanistan complained of increased pain frequency during flight. The aviators attributed this pain to body armor, which had not been worn prior to deployment. This study was conducted to investigate these complaints. A retrospective study of pain frequency among 68 deployed helicopter aviators was performed using self-reported categorical pain ratings and flight times abstracted from a safety questionnaire. To assess the association of substantial increases in flight time on reported pain frequency, study subjects were divided into a group reporting a decrease or increase of 1 h or less in average daily flight hours during deployment as compared to predeployment (level flight hours, LFH) and a group reporting an increase of greater than 1 h in average daily flight hours (increased flight hours, IFH). A significantly higher proportion of aviators in the IFH group reported an increase in pain frequency as compared to LFH (81.5% vs. 61.1%, respectively). The relative risk (RR) of increased pain frequency associated with IFH was greatest in the lower back (RR = 1.80), legs (RR = 2.60), arms (RR = 9.11), and the groin (RR = 12.1). This study provides preliminary evidence that complaints of increased pain frequency during deployment were associated with substantial increases in flight times. Further study is warranted to investigate and confirm the underlying causes of this pain. JF - Aviation, space, and environmental medicine AU - Nevin, Remington L AU - Means, Gary E AD - Combined Joint Task Force Horn of Africa, United States Africa Command, Camp Lemonier, Djibouti. remington.nevin@us.army.mil Y1 - 2009/09// PY - 2009 DA - September 2009 SP - 807 EP - 810 VL - 80 IS - 9 SN - 0095-6562, 0095-6562 KW - Index Medicus KW - Space life sciences KW - Leg KW - Lumbosacral Region KW - Humans KW - Groin KW - Cohort Studies KW - Adult KW - Retrospective Studies KW - Pain Measurement KW - Middle Aged KW - Arm KW - Time Factors KW - Pain -- etiology KW - Aviation KW - Military Personnel KW - Protective Clothing -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67645411?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Aviation%2C+space%2C+and+environmental+medicine&rft.atitle=Pain+and+discomfort+in+deployed+helicopter+aviators+wearing+body+armor.&rft.au=Nevin%2C+Remington+L%3BMeans%2C+Gary+E&rft.aulast=Nevin&rft.aufirst=Remington&rft.date=2009-09-01&rft.volume=80&rft.issue=9&rft.spage=807&rft.isbn=&rft.btitle=&rft.title=Aviation%2C+space%2C+and+environmental+medicine&rft.issn=00956562&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-10-08 N1 - Date created - 2009-09-15 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Mediastinal Kaposiform hemangioendothelioma and Kasabach-Merritt phenomenon in an infant: treatment with interferon. AN - 67638913; 19687760 AB - A 2-week-old infant developed respiratory failure due to a mediastinal Kaposiform hemangioendothelioma that was complicated by thrombocytopenia and consumptive coagulopathy. Initial surgery was unsuccessful at removing the tumorous infiltration of mediastinal structures. Multiple transfusions with fresh frozen plasma, platelets, and red blood cells were needed for the consumptive coagulopathy, and ventilatory support was required for 5 months. Therapy for the tumor included methylprednisolone, aminocaproic acid, and vincristine, but a sustained response was achieved only after the initiation of alpha interferon. The patient was monitored closely and did not develop neurologic toxicity. This case demonstrates that interferon can be used to treat infants with Kaposiform hemangioendothelioma in life-threatening situations that do not respond to other forms of treatment. JF - Journal of pediatric hematology/oncology AU - Hartman, Kip R AU - Moncur, Joel T AU - Minniti, Caterina P AU - Creamer, Kevin M AD - Uniformed Services University of the Health Sciences, Washington DC, USA. kip.hartman@us.army.mil Y1 - 2009/09// PY - 2009 DA - September 2009 SP - 690 EP - 692 VL - 31 IS - 9 KW - Aminocaproates KW - 0 KW - Interferon-alpha KW - Vincristine KW - 5J49Q6B70F KW - Methylprednisolone KW - X4W7ZR7023 KW - Index Medicus KW - Methylprednisolone -- administration & dosage KW - Plasma KW - Combined Modality Therapy KW - Humans KW - Thoracotomy KW - Thymectomy KW - Vincristine -- administration & dosage KW - Infant, Newborn KW - Respiration, Artificial KW - Aminocaproates -- administration & dosage KW - Syndrome KW - Blood Component Transfusion KW - Female KW - Disseminated Intravascular Coagulation -- etiology KW - Interferon-alpha -- therapeutic use KW - Mediastinal Neoplasms -- surgery KW - Thrombocytopenia -- therapy KW - Hemangioendothelioma -- surgery KW - Mediastinal Neoplasms -- drug therapy KW - Mediastinal Neoplasms -- complications KW - Respiratory Insufficiency -- etiology KW - Anemia, Hemolytic -- etiology KW - Hemangioendothelioma -- complications KW - Disseminated Intravascular Coagulation -- therapy KW - Respiratory Insufficiency -- therapy KW - Hemangioendothelioma -- drug therapy KW - Thrombocytopenia -- etiology KW - Anemia, Hemolytic -- therapy KW - Antineoplastic Combined Chemotherapy Protocols -- therapeutic use UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67638913?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+pediatric+hematology%2Foncology&rft.atitle=Mediastinal+Kaposiform+hemangioendothelioma+and+Kasabach-Merritt+phenomenon+in+an+infant%3A+treatment+with+interferon.&rft.au=Hartman%2C+Kip+R%3BMoncur%2C+Joel+T%3BMinniti%2C+Caterina+P%3BCreamer%2C+Kevin+M&rft.aulast=Hartman&rft.aufirst=Kip&rft.date=2009-09-01&rft.volume=31&rft.issue=9&rft.spage=690&rft.isbn=&rft.btitle=&rft.title=Journal+of+pediatric+hematology%2Foncology&rft.issn=1536-3678&rft_id=info:doi/10.1097%2FMPH.0b013e3181a1c291 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-09-22 N1 - Date created - 2009-09-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1097/MPH.0b013e3181a1c291 ER - TY - JOUR T1 - Adenovirus-transduced human butyrylcholinesterase in mouse blood functions as a bioscavenger of chemical warfare nerve agents. AN - 67591921; 19542320 AB - Human serum butyrylcholinesterase (Hu BChE) is a promising therapeutic against the toxicity of chemical warfare nerve agents. We have showed previously that recombinant (r) Hu BChE can be expressed at very high levels, 400 to 600 U/ml in mouse blood, by delivering the Hu BChE gene using adenovirus (Ad). Here, we report the biochemical properties of the Ad-expressed full-length and truncated rHu BChE in mouse blood. The molecular sizes of the full-length rHu BChE subunit and its oligomers were similar to those of native Hu BChE, although only a small portion of the full-length rHu BChE subunit underwent assembly into dimers and tetramers. As expected, Ad containing the truncated Hu BChE gene transduced the expression of monomeric rHu BChE only. Compared with 415 U of rHu BChE per milliliter in blood, tissues including liver, lung, heart, brain, kidney, muscle, intestine, diaphragm, salivary gland, and fat expressed <10 U/g of rHu BChE activity. Ad-expressed rHu BChE in mouse blood neutralized soman and O-ethyl S-2-N,N-diisopropylaminoethyl methylphosphonothiolate at rates similar to those of native Hu BChE and rHu BChE expressed in vitro. Because the expression of rHu BChE rapidly decreased 6 days after virus administration, sera were assayed for the presence of anti-Hu BChE antibodies. Anti-Hu BChE antibodies were detected on day 7 and in increased amounts thereafter, which coincided with the loss of Hu BChE expression in sera. In conclusion, the delivery of Hu BChE gene using Ad can be a promising strategy that can provide protection against multiple lethal doses of chemical warfare nerve agents in vivo. JF - Molecular pharmacology AU - Chilukuri, Nageswararao AU - Duysen, Ellen G AU - Parikh, Kalpana AU - diTargiani, Robert AU - Doctor, Bhupendra P AU - Lockridge, Oksana AU - Saxena, Ashima AD - Department of Molecular Pharmacology, Division of Biochemistry, Walter Reed Army Institute of Research, Silver Spring, MD 20910-7500, USA. nageswararao.chilukuri@us.army.mil Y1 - 2009/09// PY - 2009 DA - September 2009 SP - 612 EP - 617 VL - 76 IS - 3 KW - Chemical Warfare Agents KW - 0 KW - Cholinesterase Inhibitors KW - Recombinant Proteins KW - Soman KW - 96-64-0 KW - Butyrylcholinesterase KW - EC 3.1.1.- KW - Index Medicus KW - Animals KW - Recombinant Proteins -- metabolism KW - Humans KW - Transduction, Genetic KW - Recombinant Proteins -- blood KW - Mice KW - Tissue Distribution KW - Recombinant Proteins -- genetics KW - Mice, Knockout KW - Adenoviridae -- genetics KW - Chemical Warfare Agents -- metabolism KW - Soman -- metabolism KW - Cholinesterase Inhibitors -- metabolism KW - Butyrylcholinesterase -- metabolism KW - Butyrylcholinesterase -- genetics KW - Butyrylcholinesterase -- blood UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67591921?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Molecular+pharmacology&rft.atitle=Adenovirus-transduced+human+butyrylcholinesterase+in+mouse+blood+functions+as+a+bioscavenger+of+chemical+warfare+nerve+agents.&rft.au=Chilukuri%2C+Nageswararao%3BDuysen%2C+Ellen+G%3BParikh%2C+Kalpana%3BdiTargiani%2C+Robert%3BDoctor%2C+Bhupendra+P%3BLockridge%2C+Oksana%3BSaxena%2C+Ashima&rft.aulast=Chilukuri&rft.aufirst=Nageswararao&rft.date=2009-09-01&rft.volume=76&rft.issue=3&rft.spage=612&rft.isbn=&rft.btitle=&rft.title=Molecular+pharmacology&rft.issn=1521-0111&rft_id=info:doi/10.1124%2Fmol.109.055665 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-09-09 N1 - Date created - 2009-08-24 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1124/mol.109.055665 ER - TY - JOUR T1 - Therapeutic options to treat sulfur mustard poisoning--the road ahead. AN - 67552307; 18852011 AB - For the past 15 years the international research community has conducted a basic and applied research program aimed at identifying a medical countermeasure against chemical threat vesicant, or blistering, agents. The primary emphasis of this program has been the development of therapeutic protection against sulfur mustard and its cutaneous pathology-blister formation. In addition to the work on a medical countermeasures, significant research has been conducted on the development of topical skin protectants and medical strategies for wound healing. This review will focus on the pharmacological strategies investigated, novel therapeutic targets currently under investigation and therapeutic approaches being considered for transition to advanced development. Additionally, we will review the expansion of our understanding of the pathophysiological mechanisms of mustard injury that has come from this research. While great strides have been made through these investigations, the complexity of the mustard insult demands that further studies extend the inroads made and point the way toward better understanding of cellular and tissue disruptions caused by sulfur mustard. JF - Toxicology AU - Smith, William J AD - Research Division, US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010-5400, United States. william.j.smith3@us.army.mil Y1 - 2009/09/01/ PY - 2009 DA - 2009 Sep 01 SP - 70 EP - 73 VL - 263 IS - 1 KW - Chemical Warfare Agents KW - 0 KW - Dermatologic Agents KW - Mustard Gas KW - T8KEC9FH9P KW - Index Medicus KW - Acute Disease KW - Animals KW - Skin Absorption KW - Humans KW - Disease Models, Animal KW - Skin Diseases -- therapy KW - Chemical Warfare Agents -- poisoning KW - Poisoning -- physiopathology KW - Dermatologic Agents -- therapeutic use KW - Poisoning -- therapy KW - Skin Diseases -- chemically induced KW - Mustard Gas -- poisoning UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67552307?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology&rft.atitle=Therapeutic+options+to+treat+sulfur+mustard+poisoning--the+road+ahead.&rft.au=Smith%2C+William+J&rft.aulast=Smith&rft.aufirst=William&rft.date=2009-09-01&rft.volume=263&rft.issue=1&rft.spage=70&rft.isbn=&rft.btitle=&rft.title=Toxicology&rft.issn=1879-3185&rft_id=info:doi/10.1016%2Fj.tox.2008.09.012 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-08-21 N1 - Date created - 2009-08-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.tox.2008.09.012 ER - TY - JOUR T1 - Evaluation of protease inhibitors and an antioxidant for treatment of sulfur mustard-induced toxic lung injury. AN - 67552005; 18852015 AB - Sulfur mustard (SM)-induced lung injury has been associated with protease activation, oxidative injury and inflammatory response culminating in tissue necrosis. The protease inhibitors aprotinin and ilomastat and the antioxidant trolox were evaluated for efficacy in ameliorating SM-induced lung injury. Anesthetized spontaneously breathing rats (N=6-8/group) were intratracheally intubated and exposed to 1.4 mg/kg SM (0.35 mg SM in 0.1 ml of ethanol) or ethanol alone by vapor inhalation for 50 min. At 1 min before the exposure rats were treated with one of the following: intravenous aprotinin, 4.4 mg/kg; intraperitoneal (ip) ilomastat, 25mg/kg; or ip trolox, 500 microg/kg. Aprotinin-treated animals received supplemental 2.2mg/kg doses at 1 min and 6h post-exposure (PE). A whole body plethysmograph system was used to monitor pulmonary function (PF) parameters for 1h before exposure (baseline), and from 5-6 and 23-24h post-exposure. SM inhalation caused significant increases in several PF parameters, including tidal volume, peak inspiratory flow, peak expiratory flow, end expiratory pause and enhanced pause. Consistent with the reported development of SM-induced pathology, these changes were minimal at the 5-6-h time and significant at the 23-24-h timepoint. At the later time it is known from previous work that airways are becoming obstructed with loose cellular debris, damaged cells and exudate, which contributed to the changes in PF parameters. Treatment with aprotinin or ilomastat eliminated these PF changes, yielding results comparable with controls for each of these parameters. Lung lavage fluid analysis showed that SM caused a significant increase in total protein (TP) and in the cytokines IL-1alpha and IL-13. Aprotinin treatment prevented the increases in TP and IL-1alpha production, ilomastat prevented the increased production of IL-13, and trolox treatment did not significantly prevent the SM-related increases in TP, IL-1alpha or IL-13. Histopathologic examination of lung tissue 24h post-exposure showed minimal alveolar effects caused by SM, while damage to bronchiolar regions was much more severe due to the highly reactive nature of SM. While aprotinin and ilomastat both alleviated the PF perturbations, surprisingly only aprotinin reduced the observed pathology, both grossly and histologically. These early results indicate that treatment with aprotinin and to a lesser extent ilomastat reduces some of the direct inflammatory response and damage associated with SM-induced lung injury. This research was supported by the Defense Threat Reduction Agency - Joint Science and Technology Office, Medical S&T Division. JF - Toxicology AU - Anderson, Dana R AU - Taylor, Stephanie L AU - Fetterer, David P AU - Holmes, Wesley W AD - Medical Toxicology Branch, Analytical Toxicology Division, U.S. Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010, USA. dana.r.anderson@us.army.mil Y1 - 2009/09/01/ PY - 2009 DA - 2009 Sep 01 SP - 41 EP - 46 VL - 263 IS - 1 KW - Antioxidants KW - 0 KW - Chemical Warfare Agents KW - Chromans KW - Cytokines KW - Indoles KW - Proteins KW - Serine Proteinase Inhibitors KW - Aprotinin KW - 9087-70-1 KW - ilomastat KW - I0403ML141 KW - 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid KW - S18UL9710X KW - Mustard Gas KW - T8KEC9FH9P KW - Index Medicus KW - Respiratory Function Tests KW - Injections, Intraperitoneal KW - Animals KW - Injections, Intravenous KW - Intubation, Intratracheal KW - Lung -- pathology KW - Rats KW - Cytokines -- analysis KW - Drug Therapy, Combination KW - Rats, Sprague-Dawley KW - Bronchoalveolar Lavage Fluid -- chemistry KW - Lung -- drug effects KW - Proteins -- analysis KW - Lung -- physiopathology KW - Male KW - Serine Proteinase Inhibitors -- pharmacology KW - Lung Diseases -- chemically induced KW - Chromans -- pharmacology KW - Antioxidants -- pharmacology KW - Aprotinin -- pharmacology KW - Lung Diseases -- physiopathology KW - Indoles -- pharmacology KW - Mustard Gas -- toxicity KW - Chemical Warfare Agents -- toxicity KW - Lung Diseases -- prevention & control UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67552005?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology&rft.atitle=Evaluation+of+protease+inhibitors+and+an+antioxidant+for+treatment+of+sulfur+mustard-induced+toxic+lung+injury.&rft.au=Anderson%2C+Dana+R%3BTaylor%2C+Stephanie+L%3BFetterer%2C+David+P%3BHolmes%2C+Wesley+W&rft.aulast=Anderson&rft.aufirst=Dana&rft.date=2009-09-01&rft.volume=263&rft.issue=1&rft.spage=41&rft.isbn=&rft.btitle=&rft.title=Toxicology&rft.issn=1879-3185&rft_id=info:doi/10.1016%2Fj.tox.2008.08.025 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-08-21 N1 - Date created - 2009-08-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.tox.2008.08.025 ER - TY - JOUR T1 - Extreme sensitivity of botulinum neurotoxin domains towards mild agitation. AN - 67550178; 19226630 AB - Botulinum neurotoxins (BoNTs) and their fragments are targets of therapeutic developments and are increasingly used as therapeutic, prophylactic, and research reagents. However, published data on their properties vary widely. In order to gain a better understanding of these variations, we initiated a systematic investigation of the stability parameters of catalytic light chains (Lc) as well as of cell surface binding domains (Hc) of the neurotoxin. When followed by CD spectroscopy, we noticed that the recombinant light chains of serotypes A (LcA), B, D, E, and G rapidly lost their secondary structures by mild stirring. Denaturation of LcA increased with stirring speed and temperature resulting in a catalytically inactive precipitate. Reducing agents or an anaerobic environment were ineffective in the denaturation. Under identical conditions, bovine serum albumin, ovalbumin, carboxypeptidase B, and of thermolysin, a structural and functional analogue of LcA, remained unchanged. Hc domains of serotype A, B, C, E, and F were also denatured by mild stirring. Adding the nonionic detergent Tween-20 to LcA completely prevented the denaturation. We speculate that the BoNT domains undergo surface denaturation due to rapid exposure of hydrophobic residues by mechanical agitation. This study has important implications for handling BoNT proteins used in therapeutic development. JF - Journal of pharmaceutical sciences AU - Toth, Stephen I AU - Smith, Leonard A AU - Ahmed, S Ashraf AD - Department Molecular Biology, Integrated Toxicology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland 21702, USA. Y1 - 2009/09// PY - 2009 DA - September 2009 SP - 3302 EP - 3311 VL - 98 IS - 9 KW - Detergents KW - 0 KW - Botulinum Toxins KW - EC 3.4.24.69 KW - Index Medicus KW - Detergents -- chemistry KW - Stress, Mechanical KW - Protein Stability KW - Protein Denaturation KW - Protein Structure, Tertiary KW - Botulinum Toxins -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67550178?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+pharmaceutical+sciences&rft.atitle=Extreme+sensitivity+of+botulinum+neurotoxin+domains+towards+mild+agitation.&rft.au=Toth%2C+Stephen+I%3BSmith%2C+Leonard+A%3BAhmed%2C+S+Ashraf&rft.aulast=Toth&rft.aufirst=Stephen&rft.date=2009-09-01&rft.volume=98&rft.issue=9&rft.spage=3302&rft.isbn=&rft.btitle=&rft.title=Journal+of+pharmaceutical+sciences&rft.issn=1520-6017&rft_id=info:doi/10.1002%2Fjps.21676 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-10-12 N1 - Date created - 2009-08-04 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1002/jps.21676 ER - TY - JOUR T1 - Factors Affecting Women's Verbal Immediacy to Sexually Risky Situations AN - 59970088; 200944884 AB - The current study used a word count measure of verbal immediacy to analyze undergraduate women's responses to a set of written vignettes describing hypothetical situations involving sexual risk. Several influences on verbal immediacy were examined, including severity of previous victimization, sexual-risk proximity, relationship intimacy, and response effectiveness. Results revealed that women with a more severe history of victimization evidenced less immediacy in their responses than both women with a less severe or no history of victimization. Responses higher in immediacy were rated as more effective by a group of undergraduate peers. The interaction of risk proximity and relationship intimacy also predicted verbal immediacy. Women responded with greater immediacy to distal risk situations involving nonintimates, and less immediacy to proximal risk situations as well as distal risk situations involving intimates. [Reprinted by permission of Sage Publications Inc., copyright holder.] JF - Journal of Language and Social Psychology AU - Hoyt, Tim AU - Yeater, Elizabeth A AD - U New Mexico timothy.hoyt1@us.army.mil Y1 - 2009/09// PY - 2009 DA - September 2009 SP - 312 EP - 319 PB - Sage Publications, Thousand Oaks CA VL - 28 IS - 3 SN - 0261-927X, 0261-927X KW - sexual victimization verbal immediacy LIWC KW - Language Usage KW - Sexual Behavior KW - Intimacy KW - Females KW - Victimization KW - Risk Assessment KW - article KW - 1940: the family and socialization; sociology of sexual behavior KW - 1330: sociology of language and the arts; sociology of language/sociolinguistics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/59970088?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Asocabs&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Language+and+Social+Psychology&rft.atitle=Factors+Affecting+Women%27s+Verbal+Immediacy+to+Sexually+Risky+Situations&rft.au=Hoyt%2C+Tim%3BYeater%2C+Elizabeth+A&rft.aulast=Hoyt&rft.aufirst=Tim&rft.date=2009-09-01&rft.volume=28&rft.issue=3&rft.spage=312&rft.isbn=&rft.btitle=&rft.title=Journal+of+Language+and+Social+Psychology&rft.issn=0261927X&rft_id=info:doi/10.1177%2F0261927X09335256 LA - English DB - Sociological Abstracts N1 - Date revised - 2010-10-21 N1 - Number of references - 14 N1 - Last updated - 2016-09-28 N1 - CODEN - JLSPEB N1 - SubjectsTermNotLitGenreText - Sexual Behavior; Victimization; Risk Assessment; Language Usage; Females; Intimacy DO - http://dx.doi.org/10.1177/0261927X09335256 ER - TY - JOUR T1 - Clean Water Act 404: Regulatory Program Highlights AN - 58847413; 2008-410661 AB - The Chief of the U S. Army Corps of Engineers' Clean Water Act 404 regulatory program provides an update on the major happenings in 2009-surface coal mining, the 2008 mitigation rule, Clean Water Act jurisdiction, regional supplements to the 1987 Wetlands Delineation Manual, and more. Adapted from the source document. JF - National Wetlands Newsletter AU - Meg, Gaffney-Smith AD - U.S. Army Corps of Engineers Headquarters Office, Washington, D. C Y1 - 2009/09// PY - 2009 DA - September 2009 SP - 12 EP - 15 PB - Environmental Law Institute, Washington DC VL - 31 IS - 5 SN - 0164-0712, 0164-0712 KW - Environment and environmental policy - Water, waterways, and water management KW - Law and ethics - Law and jurisprudence KW - Environment and environmental policy - Geography and cartography KW - Administration of justice - Courts and judicial power KW - Jurisdiction KW - Wetlands KW - Legislation KW - Water supply KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58847413?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=National+Wetlands+Newsletter&rft.atitle=Clean+Water+Act+404%3A+Regulatory+Program+Highlights&rft.au=Meg%2C+Gaffney-Smith&rft.aulast=Meg&rft.aufirst=Gaffney-Smith&rft.date=2009-09-01&rft.volume=31&rft.issue=5&rft.spage=12&rft.isbn=&rft.btitle=&rft.title=National+Wetlands+Newsletter&rft.issn=01640712&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2009-11-02 N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - Water supply; Legislation; Wetlands; Jurisdiction ER - TY - JOUR T1 - Fostering a Culture of Engagement AN - 58832251; 2008-407370 AB - Whatever the reason or rationale, impairments to information dissemination can easily damage the Army's reputation and estrange the American public from one of its most trusted institutions. In the contemporary media environment, the Army must move beyond "business as usual" to embrace a culture of engagement. This dynamic mediascape can be potentially chaotic, but it also offers opportunities. Adapted from the source document. JF - Military Review AU - Caldwell IV, William B AU - Stroud, Shawn AU - Menning, Anton AD - U.S. Army Y1 - 2009/09// PY - 2009 DA - September 2009 SP - 10 EP - 18 PB - US Army Combined Arms Center, Leavenworth, KS VL - 89 IS - 5 SN - 0026-4148, 0026-4148 KW - Business and service sector - Advertising and public relations KW - Culture and religion - Intellectual life KW - Culture and religion - Culture and civilization KW - Public opinion KW - Culture KW - Public relations KW - United States Army KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58832251?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Military+Review&rft.atitle=Fostering+a+Culture+of+Engagement&rft.au=Caldwell+IV%2C+William+B%3BStroud%2C+Shawn%3BMenning%2C+Anton&rft.aulast=Caldwell+IV&rft.aufirst=William&rft.date=2009-09-01&rft.volume=89&rft.issue=5&rft.spage=10&rft.isbn=&rft.btitle=&rft.title=Military+Review&rft.issn=00264148&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2009-11-02 N1 - SuppNotes - http://usacac.army.mil/CAC2/MilitaryReview/Archives/English/MilitaryReview_ 20 091031_art005.pdf N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - United States Army; Public relations; Public opinion; Culture ER - TY - JOUR T1 - The U.S.-Iraq Security Agreement and the Changing Nature of U.S. Military Operations in Iraq AN - 58824586; 2008-407372 AB - U.S. forces in Iraq have transitioned from intelligence-driven combat operations to warrant-based operations led by Iraqi security forces. This article looks at selected provisions of the U.S.-Iraq Security Agreement, focusing on the portions of the agreement that affect U.S. military operations at the tactical level. It examines how, under the terms of the agreement, U.S. forces in Iraq have largely transitioned from intelligence driven, unilateral combat operations to warrant-based operations led by Iraqi security forces. The article also discusses Iraqi jurisdiction over U.S. forces -- an area of significant concern to U.S. commanders. Adapted from the source document. JF - Military Review AU - Ryan, Mike AU - Coats, Jason AD - U.S. Army Y1 - 2009/09// PY - 2009 DA - September 2009 SP - 48 EP - 53 PB - US Army Combined Arms Center, Leavenworth, KS VL - 89 IS - 5 SN - 0026-4148, 0026-4148 KW - International relations - International relations KW - International relations - International peace and security KW - Military and defense policy - Military planning, strategy, and operations KW - Administration of justice - Courts and judicial power KW - United States KW - Jurisdiction KW - Military operations KW - Regional security KW - Foreign relations KW - Iraq KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/58824586?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Apais&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Military+Review&rft.atitle=The+U.S.-Iraq+Security+Agreement+and+the+Changing+Nature+of+U.S.+Military+Operations+in+Iraq&rft.au=Ryan%2C+Mike%3BCoats%2C+Jason&rft.aulast=Ryan&rft.aufirst=Mike&rft.date=2009-09-01&rft.volume=89&rft.issue=5&rft.spage=48&rft.isbn=&rft.btitle=&rft.title=Military+Review&rft.issn=00264148&rft_id=info:doi/ LA - English DB - PAIS Index N1 - Date revised - 2009-11-02 N1 - SuppNotes - http://usacac.army.mil/CAC2/MilitaryReview/Archives/English/MilitaryReview_ 20 091031_art009.pdf N1 - Last updated - 2016-09-28 N1 - SubjectsTermNotLitGenreText - United States; Iraq; Foreign relations; Regional security; Military operations; Jurisdiction ER - TY - JOUR T1 - When goals constrain: Eye movements and memory for goal-Oriented map study AN - 57311996; 200924654 AB - Perspective goals, such as studying a map to learn a route through an environment or the overall layout of an environment, produce memory congruent with the goal-directed rather than the studied perspective. One explanation for this finding is that perspective goals guide attention towards actively gathering relevant information during learning. A second explanation is that information is automatically organized into a goal-congruent spatial model that guides retrieval. Both explanations predict goal-congruent memory, but only the former one predicts eye movement differences during study. The present experiment investigated the effect of perspective goals on eye movement during map study and the flexibility of resulting spatial memories. Results demonstrate eye movements towards goal-congruent map elements during learning, and lasting memory effects at test. These findings carry implications for the design of adaptive hand-held and in-vehicle navigation interfaces that accommodate for varied user goals. [Copyright John Wiley and Sons, Ltd.] JF - Applied Cognitive Psychology AU - Brunye, Tad T AU - Taylor, Holly A AD - Consumer Research & Cognitive Science, U.S. Army NSRDEC, USA tbrunye@alumni.tufts.edu Y1 - 2009/09// PY - 2009 DA - September 2009 SP - 772 EP - 787 PB - John Wiley & Sons, Chichester UK VL - 23 IS - 6 SN - 0888-4080, 0888-4080 KW - Goals KW - Learning KW - Memory KW - Flexibility KW - Eye movements KW - Navigation KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/57311996?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Applied+Cognitive+Psychology&rft.atitle=When+goals+constrain%3A+Eye+movements+and+memory+for+goal-Oriented+map+study&rft.au=Brunye%2C+Tad+T%3BTaylor%2C+Holly+A&rft.aulast=Brunye&rft.aufirst=Tad&rft.date=2009-09-01&rft.volume=23&rft.issue=6&rft.spage=772&rft.isbn=&rft.btitle=&rft.title=Applied+Cognitive+Psychology&rft.issn=08884080&rft_id=info:doi/10.1002%2Facp.1508 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2009-10-02 N1 - Last updated - 2016-09-27 N1 - CODEN - ACPSED N1 - SubjectsTermNotLitGenreText - Goals; Eye movements; Memory; Learning; Navigation; Flexibility DO - http://dx.doi.org/10.1002/acp.1508 ER - TY - JOUR T1 - Article: Commentary: Military medical support for detainee operations AN - 57301434; 200927821 AB - Abstract not available. JF - Nursing Outlook AU - Schoomaker, Eric B Y1 - 2009/09// PY - 2009 DA - September 2009 SP - 292 EP - 293 PB - Elsevier Ltd, The Netherlands VL - 57 IS - 5 SN - 0029-6554, 0029-6554 KW - Nursing KW - Military personnel KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/57301434?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Nursing+Outlook&rft.atitle=Article%3A+Commentary%3A+Military+medical+support+for+detainee+operations&rft.au=Schoomaker%2C+Eric+B&rft.aulast=Schoomaker&rft.aufirst=Eric&rft.date=2009-09-01&rft.volume=57&rft.issue=5&rft.spage=292&rft.isbn=&rft.btitle=&rft.title=Nursing+Outlook&rft.issn=00296554&rft_id=info:doi/10.1016%2Fj.outlook.2009.08.005 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2009-11-04 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Military personnel; Nursing DO - http://dx.doi.org/10.1016/j.outlook.2009.08.005 ER - TY - JOUR T1 - The distribution of metals in soils and pore water at three U.S. military training facilities AN - 50077567; 2009-095024 JF - Soil & Sediment Contamination AU - Clausen, Jay L AU - Korte, Nic Y1 - 2009/09// PY - 2009 DA - September 2009 SP - 546 EP - 563 PB - Taylor & Francis, Philadelphia, PA VL - 18 IS - 5 SN - 1549-7887, 1549-7887 KW - United States KW - zinc KW - Cape Cod KW - antimony KW - copper KW - pollution KW - lead KW - solubility KW - environmental analysis KW - soil sampling KW - ground water KW - Barnstable County Massachusetts KW - Massachusetts KW - soil pollution KW - metals KW - military facilities KW - mobility KW - pore water KW - heavy metals KW - 22:Environmental geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50077567?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Soil+%26+Sediment+Contamination&rft.atitle=The+distribution+of+metals+in+soils+and+pore+water+at+three+U.S.+military+training+facilities&rft.au=Clausen%2C+Jay+L%3BKorte%2C+Nic&rft.aulast=Clausen&rft.aufirst=Jay&rft.date=2009-09-01&rft.volume=18&rft.issue=5&rft.spage=546&rft.isbn=&rft.btitle=&rft.title=Soil+%26+Sediment+Contamination&rft.issn=15497887&rft_id=info:doi/10.1080%2F15320380903085683 L2 - http://www.tandf.co.uk/journals/titles/10588337.asp LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2009-01-01 N1 - Number of references - 34 N1 - PubXState - PA N1 - Document feature - illus. incl. 4 tables N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - antimony; Barnstable County Massachusetts; Cape Cod; copper; environmental analysis; ground water; heavy metals; lead; Massachusetts; metals; military facilities; mobility; pollution; pore water; soil pollution; soil sampling; solubility; United States; zinc DO - http://dx.doi.org/10.1080/15320380903085683 ER - TY - JOUR T1 - White paper prepared for the Secretary of Defense Task Force on DoD nuclear weapons management. Tradeoffs and paradoxes: terrorism, deterrence and nuclear weapons AN - 37154186; 3878379 AB - This article was written at the request of the Secretary of Defense Task Force on DoD Nuclear Weapons Management. While this analysis suggests that certain types of terrorists can be deterred from certain types of attacks, it is less optimistic about the use of nuclear weapons in a terrorist deterrent strategy. A broad approach to deterrence may be effective against certain types of terrorist groups and attacks, making it crucially important to disaggregate the terrorist threat when setting policy. The article goes on to address two types of terrorist groups with a "global reach" that pose a serious threat to the United States: non-state actors driven by doctrines permitting catastrophic attacks and state-sponsored groups capable of carrying out catastrophic attacks. The analysis reveals a number of previously unappreciated tradeoffs and paradoxes associated with the deterrence of terrorists. Reprinted by permission of Taylor & Francis Ltd. JF - Studies in conflict and terrorism AU - Helfstein, Scott AU - Meese, Michael AU - Rassler, Don AU - Sawyer, Reid AU - Schnack, Troy AU - Sheiffer, Mathew AU - Silverstone, Scott AU - Taylor, Scott AD - United States Military Academy Y1 - 2009/09// PY - 2009 DA - Sep 2009 SP - 776 EP - 801 VL - 32 IS - 9 SN - 1057-610X, 1057-610X KW - Political Science KW - Strategic planning KW - International relations KW - Terrorism KW - Weapons of mass destruction KW - Ideology KW - Deterrence KW - Propaganda KW - National security UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/37154186?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aibss&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Studies+in+conflict+and+terrorism&rft.atitle=White+paper+prepared+for+the+Secretary+of+Defense+Task+Force+on+DoD+nuclear+weapons+management.+Tradeoffs+and+paradoxes%3A+terrorism%2C+deterrence+and+nuclear+weapons&rft.au=Helfstein%2C+Scott%3BMeese%2C+Michael%3BRassler%2C+Don%3BSawyer%2C+Reid%3BSchnack%2C+Troy%3BSheiffer%2C+Mathew%3BSilverstone%2C+Scott%3BTaylor%2C+Scott&rft.aulast=Helfstein&rft.aufirst=Scott&rft.date=2009-09-01&rft.volume=32&rft.issue=9&rft.spage=776&rft.isbn=&rft.btitle=&rft.title=Studies+in+conflict+and+terrorism&rft.issn=1057610X&rft_id=info:doi/10.1080%2F10576100903124049 LA - English DB - International Bibliography of the Social Sciences (IBSS) N1 - Date revised - 2013-06-12 N1 - Last updated - 2013-09-16 N1 - SubjectsTermNotLitGenreText - 12686 13325; 8528; 3469 8782 13504 13501 1304 7805 3198 1077; 13504 13501 1304 7805 3198 1077; 10338 6520; 6203; 6784; 12305 9560 DO - http://dx.doi.org/10.1080/10576100903124049 ER - TY - JOUR T1 - Thumb Infection Caused by Streptococcus pseudoporcinus AN - 21494589; 12512020 AB - Streptococcus pseudoporcinus, a recently described organism found in the genitourinary tract of women, was isolated from a thumb wound in a male patient subsequent to trauma. This case describes a rarely reported non-genitourinary tract clinical isolate of S. pseudoporcinus. JF - Journal of Clinical Microbiology AU - Mahlen, Steven D AU - Clarridge III, Jill E AD - U.S. Army with duty at the Department of Laboratory Medicine, University of Washington, Jill.clarridge@va.gov Y1 - 2009/09// PY - 2009 DA - Sep 2009 SP - 3041 EP - 3042 PB - American Society for Microbiology, 1752 N Street N.W. Washington, DC 20036 USA VL - 47 IS - 9 SN - 0095-1137, 0095-1137 KW - Microbiology Abstracts B: Bacteriology KW - Streptococcus KW - Clinical isolates KW - Genitourinary tract KW - Infection KW - Wounds KW - Trauma KW - J 02400:Human Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21494589?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Microbiology&rft.atitle=Thumb+Infection+Caused+by+Streptococcus+pseudoporcinus&rft.au=Mahlen%2C+Steven+D%3BClarridge+III%2C+Jill+E&rft.aulast=Mahlen&rft.aufirst=Steven&rft.date=2009-09-01&rft.volume=47&rft.issue=9&rft.spage=3041&rft.isbn=&rft.btitle=&rft.title=Journal+of+Clinical+Microbiology&rft.issn=00951137&rft_id=info:doi/10.1128%2FJCM.00802-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-04-01 N1 - Last updated - 2013-07-15 N1 - SubjectsTermNotLitGenreText - Clinical isolates; Genitourinary tract; Infection; Trauma; Wounds; Streptococcus DO - http://dx.doi.org/10.1128/JCM.00802-09 ER - TY - JOUR T1 - Assessing the Sensitivity of Quantitative Structural Activity Analysis Models for Evaluating New Military Compounds AN - 21235811; 11715001 AB - Quantitative structural activity relationship (QSAR) models are receiving wide use because of new regulations and public scrutiny regarding new compounds entered into commerce. Accordingly, the US Department of Defense (DoD) supported this study to evaluate QSAR modeling for energetic compounds. Four compounds proposed to replace ammonium perchlorate were examined: ammonium di(nitramido)amine (ADNA); 1,3,5,5-tetranitrohexahydropyrimidine (DNNC); 1,3,3,5,7,7-hexanitro-1,5-diazacyclooctane (HCO); and diammonium di(nitramido)dinitroethylene (ADNDNE). Currently used compounds were evaluated as analogues for those under development. Ammonium dinitramide (ADN) was the analogue for ADNA; hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) for DNNC; octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) for HCO; and 1,1-diamino-2,2-dinitroethene (FOX-7) for ADNDNE. QSAR analysis was performed with the US Environmental Protection Agency's Estimation Program Interface (EPI) Suite+. The comparison of model estimates to literature values ranged from good-to-poor. Results suggested the proposed replacement compounds have low aquatic toxicities and little potential to bioaccummulate, but the uncertainty in the predictions indicates QSAR modeling with EPI Suite+ is only useful for qualitative assessments of these proposed energetic compounds. JF - Water, Air, & Soil Pollution AU - Clausen, Jay AU - Cramer, Randall AU - Clough, Stephen AU - Gray, Michael AU - Gwinn, Patrick AD - U.S. Army Engineer Research and Development Center, Cold Regions Research and Engineering Laboratory, 72 Lyme Road, Hanover, NH, 03755, USA, Jay.L.Clausen@usace.army.mil Y1 - 2009/09// PY - 2009 DA - Sep 2009 SP - 141 EP - 147 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 202 IS - 1-4 SN - 0049-6979, 0049-6979 KW - Sustainability Science Abstracts; Environment Abstracts; Pollution Abstracts KW - Ammonium KW - EPA KW - Sensitivity KW - Toxicity KW - Soil contamination KW - Military KW - perchlorate KW - M3 1010:Issues in Sustainable Development KW - P 5000:LAND POLLUTION KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21235811?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Water%2C+Air%2C+%26+Soil+Pollution&rft.atitle=Assessing+the+Sensitivity+of+Quantitative+Structural+Activity+Analysis+Models+for+Evaluating+New+Military+Compounds&rft.au=Clausen%2C+Jay%3BCramer%2C+Randall%3BClough%2C+Stephen%3BGray%2C+Michael%3BGwinn%2C+Patrick&rft.aulast=Clausen&rft.aufirst=Jay&rft.date=2009-09-01&rft.volume=202&rft.issue=1-4&rft.spage=141&rft.isbn=&rft.btitle=&rft.title=Water%2C+Air%2C+%26+Soil+Pollution&rft.issn=00496979&rft_id=info:doi/10.1007%2Fs11270-008-9964-9 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-01-01 N1 - Last updated - 2015-03-31 N1 - SubjectsTermNotLitGenreText - Sensitivity; EPA; Ammonium; Soil contamination; Toxicity; Military; perchlorate DO - http://dx.doi.org/10.1007/s11270-008-9964-9 ER - TY - JOUR T1 - Standard versus pH-adjusted and lidocaine supplemented radiocolloid for patients undergoing sentinel- lymph-node mapping and biopsy for early breast cancer (PASSION-P trial): a double-blind, randomised controlled trial AN - 21091091; 11072882 AB - Sentinel-lymph-node (SLN) mapping and biopsy maintains staging accuracy in early breast cancer and identifies patients for selective lymphadenectomy. SLN mapping requires injection of technetium-99m-sulfur colloid - an effective but sometimes painful method, for which better pain-management strategies are needed. In this randomised, double-blind trial, we compared degree of pain between standard radiocolloid injection and pH-adjusted and lidocaine-supplemented formulations for patients undergoing SLN mapping for breast cancer. Methods - Between Jan 13, 2006, and April 30, 2009, 140 patients with early breast cancer were randomly assigned in a 1:1:1:1 fashion to receive the standard topical 4% lidocaine cream and injection of [ super(99m)Tc]Tc-sulfur colloid (n=35), or to one of three other study groups: topical placebo cream and injection of Tc-sulfur colloid containing either sodium bicarbonate (n=35), 1% lidocaine (n=35), or sodium bicarbonate and 1% lidocaine (n=35). The randomisation sequence was computer generated, and all patients and investigators were masked to treatment allocation. The primary endpoint was patient-reported breast pain immediately after radioisotope injection, using the Wong-Baker FACES pain rating scale and McGill pain questionnaire, analysed in the per-protocol population. This study is registered with ClinicalTrials.gov, number NCT00940199. Findings - 19 of the 140 patients enrolled were excluded from analysis: nine declined study participation or sought care elsewhere, nine did not undergo SLN mapping because of disease extent or a technical problem, and one had unreliable data. There were no adverse events. Mean pain scores on the Wong-Baker scale (0-10) were: 6[sup].0 (SD 2[sup].6) for those who received standard of practice, 4[sup].7 (3[sup].0) for those who received radiocolloid plus bicarbonate, 1[sup].6 (1[sup].4) for those who received radiocolloid plus 1% lidocaine, and 1[sup].6 (1[sup].3) for those who received radiocolloid plus bicarbonate and 1% lidocaine (p<0[sup].0001). Mean pain rating, according to the McGill questionnaire (0-78), was 17[sup].5 (SD 11[sup].8) for the standard-of-care group, 15[sup].4 (14[sup].4) for the sodium bicarbonate group, 4[sup].6 (4[sup].5) for the 1% lidocaine group, and 3[sup].4 (5[sup].1) for the sodium bicarbonate plus 1% lidocaine group (p<0[sup].0001). SLN identification rates for each group were: 96% for the standard of care, 97% for sodium bicarbonate, 90% for 1% lidocaine, and 90% for sodium bicarbonate plus 1% lidocaine group (p=0[sup].56). Interpretation - For centres that use radiocolloid injections for SLN mapping in patients with early breast cancer, the addition of 1% lidocaine to the radioisotope solution can improve patient comfort, without compromising SLN identification. Funding - US Military Cancer Institute, the Clinical Breast Care Project, and the Army Regional Anesthesia and Pain Management Initiative. JF - Lancet Oncology AU - Stojadinovic, Alexander AU - Peoples, George E AU - Jurgens, Jennifer S AU - Howard, Robin S AU - Schuyler, Brandi AU - Crnp, Kyung H Kwon AU - Henry, Leonard R AU - Shriver, Craig D AU - Buckenmaier, C AD - Department of Surgery, Division of Surgical Oncology, Walter Reed Army Medical Center, Washington, USA, alexander.stojadinovic@amedd.army.mil Y1 - 2009/09// PY - 2009 DA - Sep 2009 SP - 849 EP - 854 PB - The Lancet Publishing Group VL - 10 IS - 9 SN - 1470-2045, 1470-2045 KW - Biotechnology and Bioengineering Abstracts; Immunology Abstracts KW - Inventories KW - Data processing KW - Colloids KW - Computers KW - Lidocaine KW - Bicarbonate KW - Biopsy KW - Pain KW - Clinical trials KW - Sodium bicarbonate KW - Anesthesia KW - Radioisotopes KW - Cream KW - Breast cancer KW - Mapping KW - F 06910:Microorganisms & Parasites KW - W 30965:Miscellaneous, Reviews UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21091091?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Lancet+Oncology&rft.atitle=Standard+versus+pH-adjusted+and+lidocaine+supplemented+radiocolloid+for+patients+undergoing+sentinel-+lymph-node+mapping+and+biopsy+for+early+breast+cancer+%28PASSION-P+trial%29%3A+a+double-blind%2C+randomised+controlled+trial&rft.au=Stojadinovic%2C+Alexander%3BPeoples%2C+George+E%3BJurgens%2C+Jennifer+S%3BHoward%2C+Robin+S%3BSchuyler%2C+Brandi%3BCrnp%2C+Kyung+H+Kwon%3BHenry%2C+Leonard+R%3BShriver%2C+Craig+D%3BBuckenmaier%2C+C&rft.aulast=Stojadinovic&rft.aufirst=Alexander&rft.date=2009-09-01&rft.volume=10&rft.issue=9&rft.spage=849&rft.isbn=&rft.btitle=&rft.title=Lancet+Oncology&rft.issn=14702045&rft_id=info:doi/10.1016%2FS1470-2045%2809%2970194-9 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-11-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Inventories; Data processing; Colloids; Computers; Lidocaine; Pain; Biopsy; Bicarbonate; Sodium bicarbonate; Clinical trials; Anesthesia; Cream; Radioisotopes; Breast cancer; Mapping DO - http://dx.doi.org/10.1016/S1470-2045(09)70194-9 ER - TY - JOUR T1 - A partial exploration of the potential energy surfaces of SCN and HSCN: Implications for the enzyme-mediated detoxification of cyanide AN - 21062714; 11035729 AB - Cyanide (CN) is considered to be a terrorist chemical weapon due to its ready availability in multi-kilogram quantities and multi-modal means of intoxication. The body uses the sulfur transferase enzyme rhodanese to detoxify cyanide via conversion of cyanide to thiocyanate. This paper explores the potential energy surfaces for the conversion of cyanide anion and hydrogen cyanide to thiocyanate anion and thiocyanic acid, respectively. The potential energy surface for the conversion of cyanide anion to thiocyanate shows that the formation of thiocyanate (SCN) is vastly preferred to formation of its isomer SNC. However, the potential energy surface for the conversion of hydrogen cyanide to thiocyanic acid reveals that the formation of HSCN and HNCS would be relatively equal. The failure for analytical methods to detect HNCS is rationalized by the observation that deprotonation of either HNCS or HSCN leads to the same thiocyanate anion. JF - Journal of Molecular Graphics and Modelling AU - Zottola, MA AD - University of Alabama-Birmingham, Birmingham, AL 35294, United States, Mark.Zottola@us.army.mil Y1 - 2009/09// PY - 2009 DA - Sep 2009 SP - 183 EP - 186 PB - Elsevier Science, The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 28 IS - 2 SN - 1093-3263, 1093-3263 KW - Biotechnology and Bioengineering Abstracts KW - Detoxification KW - Sulfur KW - Intoxication KW - thiocyanic acid KW - Anions KW - Cyanide KW - Energy KW - Hydrogen cyanide KW - Enzymes KW - rhodanese KW - Isomers KW - W 30940:Products UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21062714?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Abiotechresearch&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Molecular+Graphics+and+Modelling&rft.atitle=A+partial+exploration+of+the+potential+energy+surfaces+of+SCN+and+HSCN%3A+Implications+for+the+enzyme-mediated+detoxification+of+cyanide&rft.au=Zottola%2C+MA&rft.aulast=Zottola&rft.aufirst=MA&rft.date=2009-09-01&rft.volume=28&rft.issue=2&rft.spage=183&rft.isbn=&rft.btitle=&rft.title=Journal+of+Molecular+Graphics+and+Modelling&rft.issn=10933263&rft_id=info:doi/10.1016%2Fj.jmgm.2009.06.005 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-11-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Cyanide; Anions; Energy; Hydrogen cyanide; thiocyanic acid; Isomers; Intoxication; Sulfur; Enzymes; Detoxification; rhodanese DO - http://dx.doi.org/10.1016/j.jmgm.2009.06.005 ER - TY - JOUR T1 - Emission modeling of styrene from vinyl ester resins with low hazardous air pollutant contents AN - 20936080; 11011056 AB - Styrene is a commonly used co-monomer in vinyl ester (VE) resins, which acts as a reactive diluent and is required in most liquid molding fabrication methods to reduce viscosity and improve overall resin performance. Resins containing low hazardous air pollutant contents have been developed to reduce the styrene emissions during composite fabrication. VE monomers with a bimodal molecular weight distribution have been used to effectively decrease the amount of styrene in the system while maintaining low resin viscosities. Fatty acid vinyl ester (FAVE) resins partially replace styrene with non-volatile fatty acid monomers to reduce styrene emissions. The emissions from bimodal and FAVE resins were measured as a function of time and various parameters, including styrene content, VE molecular weight, and fatty acid monomer content and chain length. The initial emission rate from VE resins is only dependent on styrene content for constant evaporation geometry. Furthermore, the evaporation rate constant was the same regardless of VE molecular weight, styrene content, or the use of co-reactive diluent (MFA monomers). The diffusivity was not dependent on the styrene content in the resin, but decreased linearly as the VE molecular weight increased because of a corresponding increase in the resin viscosity. The diffusivity also increased as the content of MFA increased because of a decrease in the resin viscosity with high MFA content at high emission time. Furthermore, the emission profiles were accurately modeled using a modified version of 1D diffusion through a planar sheet that accounts for the depth change as a function of styrene evaporation. Overall, the model predicted emission profiles similar to the experimentally measured profiles as a function of time for various styrene contents, VE molecular weights, and fatty acid monomer contents. JF - Clean Technologies and Environmental Policy AU - La Scala, John J AU - Orlicki, Joshua A AU - Jain, Rahul AU - Ulven, Chad A AU - Palmese, Giuseppe R AU - Vaidya, Uday K AU - Sands, James M AD - US Army Research Laboratory, Weapons and Materials Research Directorate, AMSRD-ARL-WM-MC, Aberdeen Proving Ground, MD, 21005, USA, jlascala@arl.army.mil Y1 - 2009/09// PY - 2009 DA - Sep 2009 SP - 283 EP - 292 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 11 IS - 3 SN - 1618-954X, 1618-954X KW - Pollution Abstracts; Sustainability Science Abstracts KW - Styrene KW - Resins KW - composite materials KW - Evaporation KW - Esters KW - Environmental policy KW - Air pollution KW - Emissions KW - Fatty acids KW - Diffusion KW - P 0000:AIR POLLUTION KW - M3 1010:Issues in Sustainable Development UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20936080?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Assamodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Clean+Technologies+and+Environmental+Policy&rft.atitle=Emission+modeling+of+styrene+from+vinyl+ester+resins+with+low+hazardous+air+pollutant+contents&rft.au=La+Scala%2C+John+J%3BOrlicki%2C+Joshua+A%3BJain%2C+Rahul%3BUlven%2C+Chad+A%3BPalmese%2C+Giuseppe+R%3BVaidya%2C+Uday+K%3BSands%2C+James+M&rft.aulast=La+Scala&rft.aufirst=John&rft.date=2009-09-01&rft.volume=11&rft.issue=3&rft.spage=283&rft.isbn=&rft.btitle=&rft.title=Clean+Technologies+and+Environmental+Policy&rft.issn=1618954X&rft_id=info:doi/10.1007%2Fs10098-008-0181-4 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-10-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Air pollution; Styrene; Resins; composite materials; Evaporation; Fatty acids; Emissions; Diffusion; Esters; Environmental policy DO - http://dx.doi.org/10.1007/s10098-008-0181-4 ER - TY - JOUR T1 - Molecular adjuvants for malaria DNA vaccines based on the modulation of host-cell apoptosis AN - 20824888; 10980210 AB - Malaria represents a major global health problem but despite extensive efforts, no effective vaccine is available. Various vaccine candidates have been developed that provide protection in animal models, such as a gene gun-delivered DNA vaccine encoding the circumsporozoite protein (CSP) of Plasmodium berghei. A common shortcoming of most malaria vaccines is the requirement for multiple immunizations leaving room for improvement even for established vaccine candidates such as the CSP-DNA vaccine. In this study, we explored whether regulating apoptosis in DNA vaccine transfected host cells could accelerate the onset of protective immunity and provide significant protection after a single immunization. A pro-apoptotic gene (Bax) was used as a molecular adjuvant in an attempt to mimic the immunostimulatory apoptosis triggered by viral or virus- derived vaccines, while anti-apoptotic genes such as Bcl-XL may increase the life span of transfected cells thus prolonging antigen production. Surprisingly, co-delivery of either Bax or Bcl-XL greatly reduced CSP- DNA vaccine efficacy after a single immunization. Co-delivery of Bax for three immunizations still had a detrimental effect on protective immunity, while repeated co-delivery of Bcl-XL had no negative impact. The fine characterization of humoral and cellular immune response modulated by these two molecular adjuvants revealed a previously unknown effect, i.e., a shift in the Th-profile. These results demonstrate that pro- or anti-apoptotic molecules should not be used as molecular adjuvants without careful evaluation of the resulting immune response. This finding represents yet another example that strategies to enhance vaccine efficacy developed for other model systems such as viral diseases cannot easily be applied to any vaccine. JF - Vaccine AU - Bergmann-Leitner, Elke S AU - Leitner, Wolfgang W AU - Duncan, Elizabeth H AU - Savranskaya, Tatyana AU - Angov, Evelina AD - Department of Molecular Parasitology, US Military Malaria Vaccine Program, Walter Reed Army Institute of Research, 503 Robert Grant Ave, Silver Spring, MD 20910, USA, Elke.Bergmannleitner@us.army.mil Y1 - 2009/09// PY - 2009 DA - Sep 2009 SP - 5700 EP - 5708 PB - Elsevier Science, The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:usinfo-f@elsevier.com], [URL:http://www.elsevier.nl] VL - 27 IS - 41 SN - 0264-410X, 0264-410X KW - ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Biochemistry Abstracts 2: Nucleic Acids; Virology & AIDS Abstracts; Microbiology Abstracts C: Algology, Mycology & Protozoology; Immunology Abstracts KW - Malaria KW - DNA vaccine KW - Molecular adjuvant KW - Circumsporozoite protein KW - Protection KW - Human diseases KW - Apoptosis KW - Animal models KW - Disease control KW - Adjuvants KW - Immunity KW - Defence mechanisms KW - Immunization KW - Plasmodium berghei KW - Public health KW - circumsporozoite protein KW - Bcl-x protein KW - DNA vaccines KW - Immunostimulation KW - Bax protein KW - DNA KW - Immune response KW - Vaccines KW - Immune response (humoral) KW - K 03350:Immunology KW - V 22350:Immunology KW - F 06905:Vaccines KW - Q1 08484:Species interactions: parasites and diseases KW - N 14845:Miscellaneous KW - Q5 08524:Public health, medicines, dangerous organisms UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20824888?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Molecular+adjuvants+for+malaria+DNA+vaccines+based+on+the+modulation+of+host-cell+apoptosis&rft.au=Bergmann-Leitner%2C+Elke+S%3BLeitner%2C+Wolfgang+W%3BDuncan%2C+Elizabeth+H%3BSavranskaya%2C+Tatyana%3BAngov%2C+Evelina&rft.aulast=Bergmann-Leitner&rft.aufirst=Elke&rft.date=2009-09-01&rft.volume=27&rft.issue=41&rft.spage=5700&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=0264410X&rft_id=info:doi/10.1016%2Fj.vaccine.2009.06.059 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-10-01 N1 - Last updated - 2015-10-28 N1 - SubjectsTermNotLitGenreText - Human diseases; DNA; Disease control; Malaria; Immunity; Vaccines; Defence mechanisms; Immunization; Public health; Apoptosis; Animal models; Adjuvants; circumsporozoite protein; Bcl-x protein; DNA vaccines; Bax protein; Immunostimulation; Immune response; Immune response (humoral); Plasmodium berghei DO - http://dx.doi.org/10.1016/j.vaccine.2009.06.059 ER - TY - JOUR T1 - A comparison of acute and chronic toxicity methods for marine sediments AN - 20766209; 10242072 AB - Sediment toxicity tests are valuable tools for assessing the potential effects of contaminated sediments in dredged material evaluations because they inherently address complexity (e.g., unknown contaminants, mixtures, bioavailability). Although there is a need to understand the chronic and sublethal impacts of contaminants, it is common to conduct only short-term lethality tests in evaluations of marine sediments. Chronic toxicity methods for marine sediments have been developed but the efficacy of these methods is less documented. In this evaluation of marine sediments collected from the New York/New Jersey (NY/NJ) Harbor, three 10-d acute toxicity test methods (Ampelisca abdita, Leptocheirus plumulosus, Americamysis bahia) and three chronic and sublethal test methods (28-d L. plumulosus, 20- and 28-d Neanthes arenaceodentata) were applied by three testing laboratories. Although the N. arenaceodentata and A. bahia tests did not indicate significant toxicity for the sediments tested in this study, these methods have been reported useful in evaluating other sediments. The 10-d A. abdita, 10-d L. plumulosus and 28-d L. plumulosus tests were comparable between laboratories, indicating 29-43%, 29%, and 43-71% of the tested sediments as potentially toxic. The 28-d L. plumulosus method was the only chronic toxicity test that responded to the test sediments in this study. The 28-d L. plumulosus endpoint magnitudes were related to sediment chemistry and the sublethal endpoints were reduced as much or more than acute lethality endpoints. However, intra-treatment sublethal endpoint variability was greater, compromising detection of statistical significance. In this study, the chronic L. plumulosus test method was less consistent among laboratories relative to acute test methods, identifying potential for toxicity in a similar number (or slightly more) NY/NJ Harbor sediments. JF - Marine Environmental Research AU - Kennedy, A J AU - Steevens, JA AU - Lotufo, G R AU - Farrar, J D AU - Reiss, M R AU - Kropp, R K AU - Doi, J AU - Bridges, T S AD - Environmental Laboratory, CEERD-EP-R , 3909 Halls Ferry Road, Vicksburg, MS 39180-6199, United States, Alan.J.Kennedy@usace.army.mil Y1 - 2009/09// PY - 2009 DA - Sep 2009 SP - 118 EP - 127 PB - Elsevier Science, The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:usinfo-f@elsevier.com], [URL:http://www.elsevier.nl] VL - 68 IS - 3 SN - 0141-1136, 0141-1136 KW - Toxicology Abstracts; Oceanic Abstracts; Pollution Abstracts; Environment Abstracts; Water Resources Abstracts; ASFA 3: Aquatic Pollution & Environmental Quality; Aqualine Abstracts KW - toxicity testing KW - Statistics KW - USA, New Jersey KW - Toxicity tests KW - Evaluation KW - Bioavailability KW - Marine Sediments KW - Sublethal Effects KW - Ampelisca abdita KW - Sediment Contamination KW - Pollution indicators KW - Testing Procedures KW - Sediment chemistry KW - Laboratories KW - sediment chemistry KW - Leptocheirus plumulosus KW - Water Pollution Effects KW - Contaminants KW - Pollution effects KW - Acute toxicity KW - Comparative studies KW - Pollutants KW - Chronic toxicity KW - Marine KW - Sediment pollution KW - Pollution detection KW - Toxicity KW - Harbours KW - Neanthes arenaceodentata KW - Sediments KW - USA, New York KW - Americamysis bahia KW - Lethality KW - Bioaccumulation KW - Harbors KW - O 4020:Pollution - Organisms/Ecology/Toxicology KW - P 1000:MARINE POLLUTION KW - ENA 12:Oceans & Estuaries KW - SW 3030:Effects of pollution KW - AQ 00008:Effects of Pollution KW - Q5 08524:Public health, medicines, dangerous organisms KW - X 24300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20766209?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Marine+Environmental+Research&rft.atitle=A+comparison+of+acute+and+chronic+toxicity+methods+for+marine+sediments&rft.au=Kennedy%2C+A+J%3BSteevens%2C+JA%3BLotufo%2C+G+R%3BFarrar%2C+J+D%3BReiss%2C+M+R%3BKropp%2C+R+K%3BDoi%2C+J%3BBridges%2C+T+S&rft.aulast=Kennedy&rft.aufirst=A&rft.date=2009-09-01&rft.volume=68&rft.issue=3&rft.spage=118&rft.isbn=&rft.btitle=&rft.title=Marine+Environmental+Research&rft.issn=01411136&rft_id=info:doi/10.1016%2Fj.marenvres.2009.04.010 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-07-01 N1 - Last updated - 2015-10-15 N1 - SubjectsTermNotLitGenreText - Comparative studies; Sediment pollution; Pollution detection; Bioaccumulation; Pollution effects; Toxicity; Pollution indicators; Harbours; Toxicity tests; Bioavailability; Sediment chemistry; Statistics; Lethality; Chronic toxicity; Acute toxicity; Contaminants; Sediments; toxicity testing; sediment chemistry; Harbors; Evaluation; Testing Procedures; Marine Sediments; Pollutants; Sublethal Effects; Laboratories; Water Pollution Effects; Sediment Contamination; Leptocheirus plumulosus; Americamysis bahia; Ampelisca abdita; Neanthes arenaceodentata; USA, New Jersey; USA, New York; Marine DO - http://dx.doi.org/10.1016/j.marenvres.2009.04.010 ER - TY - JOUR T1 - Medical management of cutaneous sulfur mustard injuries AN - 20764143; 10271575 AB - Background: Sulfur mustard (2,2'-dichlorodiethyl sulfide; HD) is a potent vesicating chemical warfare agent that poses a continuing threat to both military and civilian populations. Significant cutaneous HD injuries can take several months to heal, necessitate lengthy hospitalizations, and result in long-term complications. There are currently no standardized or optimized methods of casualty management. New strategies are needed to provide for optimal and rapid wound healing. Objective: The primary aim of this research was to develop improved clinical strategies (treatment guidelines) for optimal treatment of superficial dermal (second degree) cutaneous HD injuries, with the goal of returning damaged skin to optimal appearance and normal function in the shortest period of time. Methods: Superficial dermal HD injuries were created on the ventral abdominal surface of weanling pigs. At 48h post-exposure, lesions were laser debrided and a treatment adjunct applied. Cultured epithelial allografts and 11 commercial off-the-shelf (COTS) products were examined for their efficacy in improving wound healing of these injuries. Clinical evaluations and a variety of non-invasive bioengineering methods were used at 7 and 14 days post-surgery to follow the progress of wound healing and evaluate various cosmetic and functional properties of the wounds. Measurements included reflectance colorimetry to measure erythema; evaporimetry to examine transepidermal water loss as a method of evaluating barrier function; torsional ballistometry to evaluate the mechanical properties of skin firmness and elasticity; and two-dimensional high frequency ultrasonography (HFU) to monitor skin thickness (e.g., edema, scar tissue). Histopathology and immunohistochemistry were performed 14 days following surgery to examine structural integrity and quality of healing. Logical Decisions super(()R) for Windows was used to rank the 12 treatment adjuncts that were studied. Results: The most efficacious treatment adjuncts included (1) Vacuum Assisted Closure(TM), V.A.C. super(()R), involving application of topical negative pressure, (2) Amino-Plex super(()R) Spray (biO sub(2) Cosmeceuticals International, Inc., Beverly Hills, CA), a nutritive cosmeceutical product that is designed to increase oxygen in cells, stimulate ATP synthesis, improve glucose transportation, stimulate collagen formation, and promote angiogenesis, and (3) ReCell super(()R) Autologous Cell Harvesting Device (Clinical Cell Culture Americas LLC, Coral Springs, Florida), an innovative medical device that was developed to allow rapid harvesting of autologous cells from a thin split-thickness biopsy followed by spray application of a population of skin cells onto wounds within 30min of collecting the biopsy, without the need of culturing the keratinocytes in a clinical laboratory. Conclusions: Complete re-epithelialization of debrided HD injuries in 7 days is possible. In general, shallow laser debridement through the basement membrane zone (100km) appears to provide better results than deeper debridement (400km) with respect to early re-epithelialization, cosmetic appearance, functional restoration, and structural integrity. Of the 12 treatment adjuncts examined, the most promising included Vacuum Assisted Closure(TM), Amino-Plex super(()R) Spray, and ReCell super(()R) Autologous Cell Harvesting Device. JF - Toxicology AU - Graham, J S AU - Stevenson, R S AU - Mitcheltree, L W AU - Hamilton, T A AU - Deckert, R R AU - Lee, R B AU - Schiavetta, A M AD - U.S. Army Medical Research Institute of Chemical Defense, 3100 Ricketts Point Road, Aberdeen Proving Ground, MD 21010, USA, john.s.graham1@us.army.mil Y1 - 2009/09/01/ PY - 2009 DA - 2009 Sep 01 SP - 47 EP - 58 PB - Elsevier Science, P.O. Box 85 Limerick Ireland VL - 263 IS - 1 SN - 0300-483X, 0300-483X KW - Environment Abstracts; Toxicology Abstracts KW - Erythema KW - Reflectance KW - USA, Florida KW - Injuries KW - Angiogenesis KW - Edema KW - Colorimetry KW - mustard gas KW - Cell culture KW - Cosmetics KW - Biopsy KW - Chemical warfare agents KW - Collagen KW - Structure-function relationships KW - Surgery KW - Water loss KW - cosmetics KW - Water springs KW - Corals KW - Keratinocytes KW - Pressure KW - Mechanical properties KW - Skin KW - Sprays KW - ATP KW - Wound healing KW - Vacuum KW - Mustard gas KW - Ultrasonography KW - Sulfide KW - Oxygen KW - Basement membranes KW - edema KW - harvesting KW - Coral reefs KW - Lasers KW - Immunohistochemistry KW - X 24490:Other KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20764143?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicology&rft.atitle=Medical+management+of+cutaneous+sulfur+mustard+injuries&rft.au=Graham%2C+J+S%3BStevenson%2C+R+S%3BMitcheltree%2C+L+W%3BHamilton%2C+T+A%3BDeckert%2C+R+R%3BLee%2C+R+B%3BSchiavetta%2C+A+M&rft.aulast=Graham&rft.aufirst=J&rft.date=2009-09-01&rft.volume=263&rft.issue=1&rft.spage=47&rft.isbn=&rft.btitle=&rft.title=Toxicology&rft.issn=0300483X&rft_id=info:doi/10.1016%2Fj.tox.2008.07.067 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Erythema; Reflectance; Injuries; Angiogenesis; Colorimetry; Edema; Biopsy; Cosmetics; Cell culture; Chemical warfare agents; Collagen; Structure-function relationships; Surgery; Water loss; Water springs; Corals; Keratinocytes; Pressure; Mechanical properties; Skin; Vacuum; Wound healing; ATP; Mustard gas; Ultrasonography; Oxygen; Sulfide; Basement membranes; Lasers; Immunohistochemistry; edema; Coral reefs; harvesting; Sprays; cosmetics; mustard gas; USA, Florida DO - http://dx.doi.org/10.1016/j.tox.2008.07.067 ER - TY - JOUR T1 - Occurrence of five classes of chemicals in indoor dust: An evaluation of the human health risks AN - 20762656; 10257379 AB - Abstract not available. JF - Science of the Total Environment AU - Hover, C AU - Banasik, M AU - Harbison, R D AU - Hardy, M AU - Price, D J AU - Stedeford, T AD - Environment and Integrated Planning Office, U.S. Army, Fort Detrick, MD 21702, USA, Carl.Hover@us.army.mil Y1 - 2009/09/01/ PY - 2009 DA - 2009 Sep 01 SP - 5194 EP - 5196 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 407 IS - 18 SN - 0048-9697, 0048-9697 KW - Risk Abstracts; Environment Abstracts KW - Chemicals KW - Dust KW - R2 23060:Medical and environmental health KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20762656?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ariskabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Science+of+the+Total+Environment&rft.atitle=Occurrence+of+five+classes+of+chemicals+in+indoor+dust%3A+An+evaluation+of+the+human+health+risks&rft.au=Hover%2C+C%3BBanasik%2C+M%3BHarbison%2C+R+D%3BHardy%2C+M%3BPrice%2C+D+J%3BStedeford%2C+T&rft.aulast=Hover&rft.aufirst=C&rft.date=2009-09-01&rft.volume=407&rft.issue=18&rft.spage=5194&rft.isbn=&rft.btitle=&rft.title=Science+of+the+Total+Environment&rft.issn=00489697&rft_id=info:doi/10.1016%2Fj.scitotenv.2009.04.019 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-08-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Chemicals; Dust DO - http://dx.doi.org/10.1016/j.scitotenv.2009.04.019 ER - TY - JOUR T1 - Laser-induced breakdown spectroscopy for detection of explosives residues: a review of recent advances, challenges, and future prospects AN - 1744705421; 13324037 AB - In this review we discuss the application of laser-induced breakdown spectroscopy (LIBS) to the problem of detection of residues of explosives. Research in this area presented in open literature is reviewed. Both laboratory and field-tested standoff LIBS instruments have been used to detect explosive materials. Recent advances in instrumentation and data analysis techniques are discussed, including the use of double-pulse LIBS to reduce air entrainment in the analytical plasma and the application of advanced chemometric techniques such as partial least-squares discriminant analysis to discriminate between residues of explosives and non-explosives on various surfaces. A number of challenges associated with detection of explosives residues using LIBS have been identified, along with their possible solutions. Several groups have investigated methods for improving the sensitivity and selectivity of LIBS for detection of explosives, including the use of femtosecond-pulse lasers, supplemental enhancement of the laser-induced plasma emission, and complementary orthogonal techniques. Despite the associated challenges, researchers have demonstrated the tremendous potential of LIBS for real-time detection of explosives residues at standoff distances. JF - Analytical and Bioanalytical Chemistry AU - Gottfried, Jennifer L AU - De Lucia Jr, Frank C AU - Munson, Chase A AU - Miziolek, Andrzej W AD - U.S. Army Research Laboratory, AMSRD-ARL-WM-BD, Aberdeen Proving Ground, Aberdeen, MD 21005-5069, USA jennifer.gottfried@us.army.mil Y1 - 2009/09// PY - 2009 DA - September 2009 SP - 283 EP - 300 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 395 IS - 2 SN - 1618-2642, 1618-2642 KW - Solid State and Superconductivity Abstracts (SO); METADEX (MD); Advanced Polymers Abstracts (EP); Environmental Engineering Abstracts (EN); Composites Industry Abstracts (ED); Engineered Materials Abstracts, Ceramics (EC) KW - Residues KW - Instrumentation KW - Discriminant analysis KW - Least squares method KW - Explosives KW - Spectroscopy KW - Breakdown KW - Mathematical analysis UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/1744705421?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvironmentalengabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Analytical+and+Bioanalytical+Chemistry&rft.atitle=Laser-induced+breakdown+spectroscopy+for+detection+of+explosives+residues%3A+a+review+of+recent+advances%2C+challenges%2C+and+future+prospects&rft.au=Gottfried%2C+Jennifer+L%3BDe+Lucia+Jr%2C+Frank+C%3BMunson%2C+Chase+A%3BMiziolek%2C+Andrzej+W&rft.aulast=Gottfried&rft.aufirst=Jennifer&rft.date=2009-09-01&rft.volume=395&rft.issue=2&rft.spage=283&rft.isbn=&rft.btitle=&rft.title=Analytical+and+Bioanalytical+Chemistry&rft.issn=16182642&rft_id=info:doi/10.1007%2Fs00216-009-2802-0 L2 - http://www.springerlink.com/content/l3x65765077822ng/?p=a01d5dfc7c4d4e09913f4349624e9272&pi=6 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-09-01 N1 - Last updated - 2016-05-18 DO - http://dx.doi.org/10.1007/s00216-009-2802-0 ER - TY - CPAPER T1 - A survey of chemical and explosives detection T2 - 2009 Conference on Optically Based Biological and Chemical Detection for Defence V AN - 42334379; 5356736 JF - 2009 Conference on Optically Based Biological and Chemical Detection for Defence V AU - Fountain III, Augustus Y1 - 2009/08/31/ PY - 2009 DA - 2009 Aug 31 KW - Explosives KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42334379?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Conference+on+Optically+Based+Biological+and+Chemical+Detection+for+Defence+V&rft.atitle=A+survey+of+chemical+and+explosives+detection&rft.au=Fountain+III%2C+Augustus&rft.aulast=Fountain+III&rft.aufirst=Augustus&rft.date=2009-08-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Conference+on+Optically+Based+Biological+and+Chemical+Detection+for+Defence+V&rft.issn=&rft_id=info:doi/ L2 - http://spie.org//app/program/index.cfm?fuseaction=conferencedetail&exp ort_id=x12520&ID=x6206&redir=x6206.xml&conference_id=888645&event_id =888639&jsenabled=1 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Utilizing active ultrasonic transducer for intrusion detection T2 - VI Conference on Unmanned/Unattended Sensors and Sensor Networks AN - 42330991; 5356782 JF - VI Conference on Unmanned/Unattended Sensors and Sensor Networks AU - Desai, Sachi AU - Quoraishee, Shafik Y1 - 2009/08/31/ PY - 2009 DA - 2009 Aug 31 KW - Ultrasonics KW - Transducers KW - Ultrasonic transducers KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42330991?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=VI+Conference+on+Unmanned%2FUnattended+Sensors+and+Sensor+Networks&rft.atitle=Utilizing+active+ultrasonic+transducer+for+intrusion+detection&rft.au=Desai%2C+Sachi%3BQuoraishee%2C+Shafik&rft.aulast=Desai&rft.aufirst=Sachi&rft.date=2009-08-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=VI+Conference+on+Unmanned%2FUnattended+Sensors+and+Sensor+Networks&rft.issn=&rft_id=info:doi/ L2 - http://spie.org/Documents/ConferencesExhibitions/ERS-ESD09%20Final%20t o%20press.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Discovery, invention and innovation for combating irregular warfare T2 - VI Conference on Unmanned/Unattended Sensors and Sensor Networks AN - 42328340; 5356752 JF - VI Conference on Unmanned/Unattended Sensors and Sensor Networks AU - Chabalowsky, Cary Y1 - 2009/08/31/ PY - 2009 DA - 2009 Aug 31 KW - Innovations KW - Inventions KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42328340?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=VI+Conference+on+Unmanned%2FUnattended+Sensors+and+Sensor+Networks&rft.atitle=Discovery%2C+invention+and+innovation+for+combating+irregular+warfare&rft.au=Chabalowsky%2C+Cary&rft.aulast=Chabalowsky&rft.aufirst=Cary&rft.date=2009-08-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=VI+Conference+on+Unmanned%2FUnattended+Sensors+and+Sensor+Networks&rft.issn=&rft_id=info:doi/ L2 - http://spie.org/Documents/ConferencesExhibitions/ERS-ESD09%20Final%20t o%20press.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Millimeter wave sensor requirements for maritime small craft identifi cation T2 - 2009 Conference on Millimetre Wave and Terahertz Sensors and Technology AN - 42326402; 5355110 JF - 2009 Conference on Millimetre Wave and Terahertz Sensors and Technology AU - Krapels, Keith AU - Boettcher, Evelyn Y1 - 2009/08/31/ PY - 2009 DA - 2009 Aug 31 KW - Cations KW - Sensors KW - Waves KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42326402?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Conference+on+Millimetre+Wave+and+Terahertz+Sensors+and+Technology&rft.atitle=Millimeter+wave+sensor+requirements+for+maritime+small+craft+identifi+cation&rft.au=Krapels%2C+Keith%3BBoettcher%2C+Evelyn&rft.aulast=Krapels&rft.aufirst=Keith&rft.date=2009-08-31&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Conference+on+Millimetre+Wave+and+Terahertz+Sensors+and+Technology&rft.issn=&rft_id=info:doi/ L2 - http://spie.org/Documents/ConferencesExhibitions/ERS-ESD09%20Final%20t o%20press.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Using Soil Stress State Transducers in Freezing Ground T2 - 14th Conference on Cold Regions Engineering AN - 42384335; 5383818 JF - 14th Conference on Cold Regions Engineering AU - Shoop, Sally AU - Coutermarsh, Barry AU - Diemand, Deborah AU - Way, Thomas Y1 - 2009/08/30/ PY - 2009 DA - 2009 Aug 30 KW - Soil KW - Stress KW - Transducers KW - Freezing KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42384335?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=14th+Conference+on+Cold+Regions+Engineering&rft.atitle=Using+Soil+Stress+State+Transducers+in+Freezing+Ground&rft.au=Shoop%2C+Sally%3BCoutermarsh%2C+Barry%3BDiemand%2C+Deborah%3BWay%2C+Thomas&rft.aulast=Shoop&rft.aufirst=Sally&rft.date=2009-08-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=14th+Conference+on+Cold+Regions+Engineering&rft.issn=&rft_id=info:doi/ L2 - http://content.asce.org/files/pdf/FinalProgramFINALforWeb.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Using Ice Surfaces to Decrease the Impa ct of a Remediation Project T2 - 14th Conference on Cold Regions Engineering AN - 42384245; 5383791 JF - 14th Conference on Cold Regions Engineering AU - Walsh, Michael AU - Zufelt, Jon AU - Collins, Charles Y1 - 2009/08/30/ PY - 2009 DA - 2009 Aug 30 KW - Ice KW - Bioremediation KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42384245?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=14th+Conference+on+Cold+Regions+Engineering&rft.atitle=Using+Ice+Surfaces+to+Decrease+the+Impa+ct+of+a+Remediation+Project&rft.au=Walsh%2C+Michael%3BZufelt%2C+Jon%3BCollins%2C+Charles&rft.aulast=Walsh&rft.aufirst=Michael&rft.date=2009-08-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=14th+Conference+on+Cold+Regions+Engineering&rft.issn=&rft_id=info:doi/ L2 - http://content.asce.org/files/pdf/FinalProgramFINALforWeb.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Geophysical Investigations at Shishmaref, Alaska T2 - 14th Conference on Cold Regions Engineering AN - 42380742; 5383783 JF - 14th Conference on Cold Regions Engineering AU - Azelton, Mary AU - Epps, Lewis AU - Astley, Beth AU - Jon E. Zufelt, AU - Bjella, Kevin Y1 - 2009/08/30/ PY - 2009 DA - 2009 Aug 30 KW - USA, Alaska KW - Geophysics KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42380742?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=14th+Conference+on+Cold+Regions+Engineering&rft.atitle=Geophysical+Investigations+at+Shishmaref%2C+Alaska&rft.au=Azelton%2C+Mary%3BEpps%2C+Lewis%3BAstley%2C+Beth%3BJon+E.+Zufelt%2C%3BBjella%2C+Kevin&rft.aulast=Azelton&rft.aufirst=Mary&rft.date=2009-08-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=14th+Conference+on+Cold+Regions+Engineering&rft.issn=&rft_id=info:doi/ L2 - http://content.asce.org/files/pdf/FinalProgramFINALforWeb.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Modeling Heavy Wheel Loading on Frozen and Unfrozen Ground T2 - 14th Conference on Cold Regions Engineering AN - 42380461; 5383779 DE: JF - 14th Conference on Cold Regions Engineering AU - Parker, Michael AU - Coutermarsh, Barry AU - Shoop, Sally Y1 - 2009/08/30/ PY - 2009 DA - 2009 Aug 30 KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42380461?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=14th+Conference+on+Cold+Regions+Engineering&rft.atitle=Modeling+Heavy+Wheel+Loading+on+Frozen+and+Unfrozen+Ground&rft.au=Parker%2C+Michael%3BCoutermarsh%2C+Barry%3BShoop%2C+Sally&rft.aulast=Parker&rft.aufirst=Michael&rft.date=2009-08-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=14th+Conference+on+Cold+Regions+Engineering&rft.issn=&rft_id=info:doi/ L2 - http://content.asce.org/files/pdf/FinalProgramFINALforWeb.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Extending the Season for Concrete Construction and Repa ir: The Next Phase T2 - 14th Conference on Cold Regions Engineering AN - 42379070; 5383797 JF - 14th Conference on Cold Regions Engineering AU - Barna, Lynette AU - Seman, Peter AU - Korhonen, Charles Y1 - 2009/08/30/ PY - 2009 DA - 2009 Aug 30 KW - Concrete KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42379070?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=14th+Conference+on+Cold+Regions+Engineering&rft.atitle=Extending+the+Season+for+Concrete+Construction+and+Repa+ir%3A+The+Next+Phase&rft.au=Barna%2C+Lynette%3BSeman%2C+Peter%3BKorhonen%2C+Charles&rft.aulast=Barna&rft.aufirst=Lynette&rft.date=2009-08-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=14th+Conference+on+Cold+Regions+Engineering&rft.issn=&rft_id=info:doi/ L2 - http://content.asce.org/files/pdf/FinalProgramFINALforWeb.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Characterizing the Strength Layering of Freezing Ground T2 - 14th Conference on Cold Regions Engineering AN - 42379025; 5383784 JF - 14th Conference on Cold Regions Engineering AU - Affleck, Rosa AU - Shoop, Sally Y1 - 2009/08/30/ PY - 2009 DA - 2009 Aug 30 KW - Freezing KW - U 4300:Environmental Science UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42379025?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=14th+Conference+on+Cold+Regions+Engineering&rft.atitle=Characterizing+the+Strength+Layering+of+Freezing+Ground&rft.au=Affleck%2C+Rosa%3BShoop%2C+Sally&rft.aulast=Affleck&rft.aufirst=Rosa&rft.date=2009-08-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=14th+Conference+on+Cold+Regions+Engineering&rft.issn=&rft_id=info:doi/ L2 - http://content.asce.org/files/pdf/FinalProgramFINALforWeb.pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Highly Integrated Piezomems Enabled Millimeter-Scale Robotics T2 - 2009 American Society of Mechanical Engineers International Design Engineering Technical Conferences (IDETC/CIE 2009) AN - 42307218; 5342649 JF - 2009 American Society of Mechanical Engineers International Design Engineering Technical Conferences (IDETC/CIE 2009) AU - Pulskamp, Jeff AU - Polcawich, Ronald AU - Oldham, Kenn Y1 - 2009/08/30/ PY - 2009 DA - 2009 Aug 30 KW - Robotics KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42307218?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+American+Society+of+Mechanical+Engineers+International+Design+Engineering+Technical+Conferences+%28IDETC%2FCIE+2009%29&rft.atitle=Highly+Integrated+Piezomems+Enabled+Millimeter-Scale+Robotics&rft.au=Pulskamp%2C+Jeff%3BPolcawich%2C+Ronald%3BOldham%2C+Kenn&rft.aulast=Pulskamp&rft.aufirst=Jeff&rft.date=2009-08-30&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+American+Society+of+Mechanical+Engineers+International+Design+Engineering+Technical+Conferences+%28IDETC%2FCIE+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.asmeconferences.org/IDETC09/ConferenceSchedule.cfm LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - A Usability Evaluation of Distributed Common Ground System - Army (DCGS-A): Design Recommendations T2 - International Conference on Human Computer Interaction (ICHCI 2009) AN - 42377196; 5372543 DE: JF - International Conference on Human Computer Interaction (ICHCI 2009) AU - Rovira, Ericka AU - Mckay, Allyson AU - Mateer, Don AU - Savarie, Zach AU - Usher, Bobbi Y1 - 2009/08/26/ PY - 2009 DA - 2009 Aug 26 KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42377196?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=International+Conference+on+Human+Computer+Interaction+%28ICHCI+2009%29&rft.atitle=A+Usability+Evaluation+of+Distributed+Common+Ground+System+-+Army+%28DCGS-A%29%3A+Design+Recommendations&rft.au=Rovira%2C+Ericka%3BMckay%2C+Allyson%3BMateer%2C+Don%3BSavarie%2C+Zach%3BUsher%2C+Bobbi&rft.aulast=Rovira&rft.aufirst=Ericka&rft.date=2009-08-26&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=International+Conference+on+Human+Computer+Interaction+%28ICHCI+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.hcii2009.org/program.php LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Harnessing the Power of Multiple Tools to Predict and Mitigate Mental Overload T2 - International Conference on Human Computer Interaction (ICHCI 2009) AN - 42372452; 5373335 DE: JF - International Conference on Human Computer Interaction (ICHCI 2009) AU - Samms, Charneta AU - Jones, David AU - Hale, Kelly AU - Mitchell, Diane Y1 - 2009/08/26/ PY - 2009 DA - 2009 Aug 26 KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42372452?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=International+Conference+on+Human+Computer+Interaction+%28ICHCI+2009%29&rft.atitle=Harnessing+the+Power+of+Multiple+Tools+to+Predict+and+Mitigate+Mental+Overload&rft.au=Samms%2C+Charneta%3BJones%2C+David%3BHale%2C+Kelly%3BMitchell%2C+Diane&rft.aulast=Samms&rft.aufirst=Charneta&rft.date=2009-08-26&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=International+Conference+on+Human+Computer+Interaction+%28ICHCI+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.hcii2009.org/program.php LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Understanding Brain, Cognition, and Behavior in Complex Dynamic Environments T2 - International Conference on Human Computer Interaction (ICHCI 2009) AN - 42360317; 5372142 JF - International Conference on Human Computer Interaction (ICHCI 2009) AU - Kerick, Scott AU - McDowell, Kaleb Y1 - 2009/08/26/ PY - 2009 DA - 2009 Aug 26 KW - Cognitive ability KW - Brain KW - Cognition KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42360317?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=International+Conference+on+Human+Computer+Interaction+%28ICHCI+2009%29&rft.atitle=Understanding+Brain%2C+Cognition%2C+and+Behavior+in+Complex+Dynamic+Environments&rft.au=Kerick%2C+Scott%3BMcDowell%2C+Kaleb&rft.aulast=Kerick&rft.aufirst=Scott&rft.date=2009-08-26&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=International+Conference+on+Human+Computer+Interaction+%28ICHCI+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.hcii2009.org/program.php LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Overview of Meta-analyses Investigating Vibrotactile Versus Visual Display Options T2 - International Conference on Human Computer Interaction (ICHCI 2009) AN - 42356422; 5373073 JF - International Conference on Human Computer Interaction (ICHCI 2009) AU - Elliott, Linda AU - Coovert, Michael AU - Redden, Elizabeth Y1 - 2009/08/26/ PY - 2009 DA - 2009 Aug 26 KW - Reviews KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42356422?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=International+Conference+on+Human+Computer+Interaction+%28ICHCI+2009%29&rft.atitle=Overview+of+Meta-analyses+Investigating+Vibrotactile+Versus+Visual+Display+Options&rft.au=Elliott%2C+Linda%3BCoovert%2C+Michael%3BRedden%2C+Elizabeth&rft.aulast=Elliott&rft.aufirst=Linda&rft.date=2009-08-26&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=International+Conference+on+Human+Computer+Interaction+%28ICHCI+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://www.hcii2009.org/program.php LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-12-18 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Structure and reactivity of TNT and related species: Application of spectroscopic approaches and quantum-chemical approximations toward understanding transformation mechanisms AN - 20625454; 9334083 AB - This paper presents our latest findings regarding the structure and reactivity of the nitroaromatics, TNT and selected derivatives, within their environmental context. We also demonstrate the useful and proactive role of combined computational chemistry and spectroscopy tools in studying competing transformation mechanisms, particularly those with toxic potential. TNT and selected derivatives were reacted via alkaline hydrolysis as well as via free radical initiators through monochromatic irradiation and through Fenton reactions in complex competing transformation mechanisms. Only alkaline hydrolysis produced consistent and effective transformation intermediate and final products in this research. However, irradiation of the product generated by alkaline hydrolysis at 450nm (wavelength of maximum absorption) caused complete disappearance of the spectra. JF - Journal of Hazardous Materials AU - Qasim, M AU - Gorb, L AU - Magers, D AU - Honea, P AU - Leszczynski, J AU - Moore, B AU - Taylor, L AU - Middleton, M AD - 3909 Halls Ferry Road, Vicksburg, MS 39180, United States, qasimm@erdc.usace.army.mil Y1 - 2009/08/15/ PY - 2009 DA - 2009 Aug 15 SP - 154 EP - 163 PB - Elsevier Science, P.O. Box 211 Amsterdam 1000 AE Netherlands, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl/] VL - 167 IS - 1-3 SN - 0304-3894, 0304-3894 KW - Toxicology Abstracts; Environment Abstracts KW - Transformation KW - Free radicals KW - Spectroscopy KW - Computer applications KW - Hydrolysis KW - 2,4,6-Trinitrotoluene KW - Radiation KW - Irradiation KW - Absorption KW - Wavelength KW - ENA 21:Wildlife KW - X 24350:Industrial Chemicals UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20625454?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Hazardous+Materials&rft.atitle=Structure+and+reactivity+of+TNT+and+related+species%3A+Application+of+spectroscopic+approaches+and+quantum-chemical+approximations+toward+understanding+transformation+mechanisms&rft.au=Qasim%2C+M%3BGorb%2C+L%3BMagers%2C+D%3BHonea%2C+P%3BLeszczynski%2C+J%3BMoore%2C+B%3BTaylor%2C+L%3BMiddleton%2C+M&rft.aulast=Qasim&rft.aufirst=M&rft.date=2009-08-15&rft.volume=167&rft.issue=1-3&rft.spage=154&rft.isbn=&rft.btitle=&rft.title=Journal+of+Hazardous+Materials&rft.issn=03043894&rft_id=info:doi/10.1016%2Fj.jhazmat.2008.12.105 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-06-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Transformation; 2,4,6-Trinitrotoluene; Radiation; Free radicals; Wavelength; Computer applications; Spectroscopy; Hydrolysis; Irradiation; Absorption DO - http://dx.doi.org/10.1016/j.jhazmat.2008.12.105 ER - TY - CPAPER T1 - Toward Instrumenting Network Warfare Competitions to Generate Labeled Datasets T2 - 2nd Workshop on Cyber Security Experimentation and Test (CSET 09) AN - 40403388; 5296771 JF - 2nd Workshop on Cyber Security Experimentation and Test (CSET 09) AU - Sangster, Benjamin AU - O'Connor, T AU - Cook, Thomas AU - Fanelli, Robert AU - Dean, Erik AU - Adams, William AU - Morrell, Chris AU - Conti, Gregory Y1 - 2009/08/10/ PY - 2009 DA - 2009 Aug 10 KW - Competition KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40403388?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2nd+Workshop+on+Cyber+Security+Experimentation+and+Test+%28CSET+09%29&rft.atitle=Toward+Instrumenting+Network+Warfare+Competitions+to+Generate+Labeled+Datasets&rft.au=Sangster%2C+Benjamin%3BO%27Connor%2C+T%3BCook%2C+Thomas%3BFanelli%2C+Robert%3BDean%2C+Erik%3BAdams%2C+William%3BMorrell%2C+Chris%3BConti%2C+Gregory&rft.aulast=Sangster&rft.aufirst=Benjamin&rft.date=2009-08-10&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2nd+Workshop+on+Cyber+Security+Experimentation+and+Test+%28CSET+09%29&rft.issn=&rft_id=info:doi/ L2 - http://www.usenix.org/events/cset09/tech/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-09-28 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Collective Views of the NSA/CSS Cyber Defense Exercise on Curricula and Learning Objectives T2 - 2nd Workshop on Cyber Security Experimentation and Test (CSET 09) AN - 40398371; 5296764 JF - 2nd Workshop on Cyber Security Experimentation and Test (CSET 09) AU - Adams, William AU - Gavas, Efstratios AU - Lacey, Tim AU - Leblanc, Sylvain Y1 - 2009/08/10/ PY - 2009 DA - 2009 Aug 10 KW - Learning KW - Physical training KW - Curricula KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40398371?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2nd+Workshop+on+Cyber+Security+Experimentation+and+Test+%28CSET+09%29&rft.atitle=Collective+Views+of+the+NSA%2FCSS+Cyber+Defense+Exercise+on+Curricula+and+Learning+Objectives&rft.au=Adams%2C+William%3BGavas%2C+Efstratios%3BLacey%2C+Tim%3BLeblanc%2C+Sylvain&rft.aulast=Adams&rft.aufirst=William&rft.date=2009-08-10&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2nd+Workshop+on+Cyber+Security+Experimentation+and+Test+%28CSET+09%29&rft.issn=&rft_id=info:doi/ L2 - http://www.usenix.org/events/cset09/tech/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-09-28 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Computations of Supersonic Flow over a Complex Elliptical Missile Configuration T2 - 2009 AIAA Atmospheric Flight Mechanics Conference (AFM) AN - 40344844; 5268974 JF - 2009 AIAA Atmospheric Flight Mechanics Conference (AFM) AU - Sahu, J AU - Heavey, K Y1 - 2009/08/10/ PY - 2009 DA - 2009 Aug 10 KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40344844?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+AIAA+Atmospheric+Flight+Mechanics+Conference+%28AFM%29&rft.atitle=Computations+of+Supersonic+Flow+over+a+Complex+Elliptical+Missile+Configuration&rft.au=Sahu%2C+J%3BHeavey%2C+K&rft.aulast=Sahu&rft.aufirst=J&rft.date=2009-08-10&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+AIAA+Atmospheric+Flight+Mechanics+Conference+%28AFM%29&rft.issn=&rft_id=info:doi/ L2 - http://www.aiaa.org/agenda.cfm?lumeetingid=2000&viewcon=agenda&formatv iew=1&DateGet=10-Aug-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-09-28 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Immune interference after sequential alphavirus vaccine vaccinations. AN - 67513337; 19576665 AB - We compared the effect of order of administration of investigational alphavirus vaccines on neutralizing antibody response. Volunteers who received the inactivated eastern and western equine encephalitis (EEE and WEE) vaccines before live attenuated Venezuelan (VEE) vaccine had significantly lower rates of antibody response than those receiving VEE vaccine before EEE and WEE vaccines (66.7% vs. 80.6%; p=0.026). The odds of having a VEE antibody non-response among those initially receiving EEE and WEE vaccines, adjusted for gender, were significant (odds ratio [OR]=2.20; 95% CI=1.2-4.1 [p=0.0145]) as were the odds of non-response among females adjusted for group (OR=1.81; 95% CI=1.2-2.7 [p=0.0037]). Antibody interference and gender effect have major implications for vaccine strategy among those receiving multiple alphavirus vaccines and those developing next generation vaccines for these threats. JF - Vaccine AU - Pittman, Phillip R AU - Liu, Ching-Tong AU - Cannon, Timothy L AU - Mangiafico, Joseph A AU - Gibbs, Paul H AD - US Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702-5011, United States. phillip.pittman@amedd.army.mil Y1 - 2009/08/06/ PY - 2009 DA - 2009 Aug 06 SP - 4879 EP - 4882 VL - 27 IS - 36 KW - Antibodies, Viral KW - 0 KW - Viral Vaccines KW - Index Medicus KW - Drug Interactions KW - Humans KW - Neutralization Tests KW - Male KW - Female KW - Antibodies, Viral -- blood KW - Encephalitis Virus, Eastern Equine -- immunology KW - Viral Vaccines -- immunology KW - Immunization Schedule KW - Encephalitis Virus, Western Equine -- immunology KW - Encephalitis Virus, Venezuelan Equine -- immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67513337?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Immune+interference+after+sequential+alphavirus+vaccine+vaccinations.&rft.au=Pittman%2C+Phillip+R%3BLiu%2C+Ching-Tong%3BCannon%2C+Timothy+L%3BMangiafico%2C+Joseph+A%3BGibbs%2C+Paul+H&rft.aulast=Pittman&rft.aufirst=Phillip&rft.date=2009-08-06&rft.volume=27&rft.issue=36&rft.spage=4879&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=1873-2518&rft_id=info:doi/10.1016%2Fj.vaccine.2009.02.090 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-09-08 N1 - Date created - 2009-07-22 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.vaccine.2009.02.090 ER - TY - JOUR T1 - Epileptogenic potential of mefloquine chemoprophylaxis: a pathogenic hypothesis. AN - 67633899; 19656408 AB - Mefloquine has historically been considered safe and well-tolerated for long-term malaria chemoprophylaxis, but prescribing it requires careful attention in order to rule out contraindications to its use. Contraindications include a history of certain neurological conditions that might increase the risk of seizure and other adverse events. The precise pathophysiological mechanism by which mefloquine might predispose those with such a history to seizure remains unclear. Studies have demonstrated that mefloquine at doses consistent with chemoprophylaxis accumulates at high levels in brain tissue, which results in altered neuronal calcium homeostasis, altered gap-junction functioning, and contributes to neuronal cell death. This paper reviews the scientific evidence associating mefloquine with alterations in neuronal function, and it suggests the novel hypothesis that among those with the prevalent EPM1 mutation, inherited and mefloquine-induced impairments in neuronal physiologic safeguards might increase risk of GABAergic seizure during mefloquine chemoprophylaxis. Consistent with case reports of tonic-clonic seizures occurring during mefloquine chemoprophylaxis among those with family histories of epilepsy, it is proposed here that a new contraindication to mefloquine use be recognized for people with EPM1 mutation and for those with a personal history of myoclonus or ataxia, or a family history of degenerative neurologic disorder consistent with EPM1. Recommendations and directions for future research are presented. JF - Malaria journal AU - Nevin, Remington L AD - United States Africa Command, Combined Joint Task Force Horn of Africa, Camp Lemonier, FPO AE 09363, Republic of Djibouti. remington.nevin@us.army.mil Y1 - 2009/08/05/ PY - 2009 DA - 2009 Aug 05 SP - 188 VL - 8 KW - Antimalarials KW - 0 KW - Mefloquine KW - TML814419R KW - Index Medicus KW - Humans KW - Seizures -- chemically induced KW - Antimalarials -- adverse effects KW - Mefloquine -- adverse effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67633899?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Malaria+journal&rft.atitle=Epileptogenic+potential+of+mefloquine+chemoprophylaxis%3A+a+pathogenic+hypothesis.&rft.au=Nevin%2C+Remington+L&rft.aulast=Nevin&rft.aufirst=Remington&rft.date=2009-08-05&rft.volume=8&rft.issue=&rft.spage=188&rft.isbn=&rft.btitle=&rft.title=Malaria+journal&rft.issn=1475-2875&rft_id=info:doi/10.1186%2F1475-2875-8-188 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-10-02 N1 - Date created - 2009-09-02 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Clin Pharmacokinet. 1990 Oct;19(4):264-79 [2208897] Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7573-8 [10861019] Am J Trop Med Hyg. 1991 Aug;45(2):263-70 [1877722] J Trop Med Hyg. 1992 Jun;95(3):167-79 [1597872] Lancet. 1993 May 22;341(8856):1299-303 [8098447] Med J Aust. 1994 Oct 3;161(7):453 [7935106] Forensic Sci Int. 1994 Sep 6;68(1):29-32 [7959478] Trans R Soc Trop Med Hyg. 1995 Jul-Aug;89(4):434 [7570889] BMJ. 1996 Aug 31;313(7056):525-8 [8789977] Biochem Pharmacol. 1996 Nov 22;52(10):1545-52 [8937469] Arch Int Pharmacodyn Ther. 1996 May-Jun;331(3):221-31 [9124995] Nat Genet. 1998 Nov;20(3):251-8 [9806543] Int J Clin Pharmacol Ther. 1999 Jan;37(1):58-61 [10027484] Glia. 2005 Jun;50(4):351-61 [15846800] Prog Neuropsychopharmacol Biol Psychiatry. 2005 Jul;29(6):917-21 [16009480] Genomics. 2005 Nov;86(5):539-50 [16109470] Antimicrob Agents Chemother. 2006 Mar;50(3):1045-53 [16495267] Synapse. 2006 Jul;60(1):20-31 [16575850] Am J Trop Med Hyg. 2006 May;74(5):744-9 [16687673] Clin Pharmacol Ther. 2006 Oct;80(4):367-74 [17015054] Mov Disord. 2006 Oct;21(10):1641-9 [16773639] JAMA. 2006 Nov 8;296(18):2234-44 [17090770] Brain Res Bull. 2006 Dec 11;71(1-3):23-8 [17113924] Antimicrob Agents Chemother. 2006 Dec;50(12):4132-43 [16966402] Neurotherapeutics. 2007 Jan;4(1):18-61 [17199015] Neurobiol Dis. 2007 Mar;25(3):675-85 [17188503] Epilepsia. 2007 Apr;48(4):752-7 [17319918] JAMA. 2007 May 23;297(20):2251-63 [17519415] J Travel Med. 2000 May-Jun;7(3):155-6 [11179947] Hum Mol Genet. 2001 Sep 1;10(18):1867-71 [11555622] Eur J Clin Pharmacol. 2002 Sep;58(6):441-5 [12242605] Clin Neuropharmacol. 2002 Sep-Oct;25(5):243 [12410053] J Neuropathol Exp Neurol. 2002 Dec;61(12):1085-91 [12484571] Presse Med. 2003 Mar 8;32(9):408 [12712918] Cerebellum. 2002 Jan-Mar;1(1):91-2 [12879977] Malar J. 2003 Jun 12;2:14 [12848898] Biochem Soc Symp. 2003;(70):179-99 [14587292] Br J Pharmacol. 2004 Apr;141(7):1214-22 [15023856] Proc Natl Acad Sci U S A. 2004 May 4;101(18):7164-9 [15103021] Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12364-9 [15297615] Eur J Pharm Sci. 2007 Oct;32(2):123-7 [17698330] Malar J. 2008;7:30 [18267019] Epilepsia. 2008 Apr;49(4):557-63 [18028412] Epilepsia. 2008 Apr;49(4):549-56 [18325013] J Neurosci Res. 2008 Aug 1;86(10):2147-58 [18381762] J Neurochem. 2008 Aug;106(3):1000-16 [18410504] Basic Clin Pharmacol Toxicol. 2008 Sep;103(3):209-13 [18684232] Sleep. 2008 Dec;31(12):1647-54 [19090320] Travel Med Infect Dis. 2009 Jan;7(1):2-6 [19174293] Natl Med J India. 2000 Jan-Feb;13(1):47 [10743379] Ann Intern Med. 1991 Jun 1;114(11):994 [2024874] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1186/1475-2875-8-188 ER - TY - CPAPER T1 - Airborne IR persistent surveillance imaging requirements for Army aircraft T2 - 2009 Conference on Optics + Photonics AN - 42329245; 5351525 JF - 2009 Conference on Optics + Photonics AU - Groenert, Michael Y1 - 2009/08/02/ PY - 2009 DA - 2009 Aug 02 KW - Aircraft KW - Imaging techniques KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42329245?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Conference+on+Optics+%2B+Photonics&rft.atitle=Airborne+IR+persistent+surveillance+imaging+requirements+for+Army+aircraft&rft.au=Groenert%2C+Michael&rft.aulast=Groenert&rft.aufirst=Michael&rft.date=2009-08-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Conference+on+Optics+%2B+Photonics&rft.issn=&rft_id=info:doi/ L2 - http://spie.org/Documents/ConferencesExhibitions/OP09-final-program-L. pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Plasmonic nanorectennas for energy conversion T2 - 2009 Conference on Optics + Photonics AN - 42323300; 5348726 JF - 2009 Conference on Optics + Photonics AU - Osgood III, Richard AU - Kimball, Brian AU - Carlson, Joel AU - Ziegler, David AU - Welch, James AU - Belton, Lauren AU - Fernandes, Gustavo AU - Liu, Zhijun AU - Xu, Jimmy Y1 - 2009/08/02/ PY - 2009 DA - 2009 Aug 02 KW - Energy KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42323300?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Conference+on+Optics+%2B+Photonics&rft.atitle=Plasmonic+nanorectennas+for+energy+conversion&rft.au=Osgood+III%2C+Richard%3BKimball%2C+Brian%3BCarlson%2C+Joel%3BZiegler%2C+David%3BWelch%2C+James%3BBelton%2C+Lauren%3BFernandes%2C+Gustavo%3BLiu%2C+Zhijun%3BXu%2C+Jimmy&rft.aulast=Osgood+III&rft.aufirst=Richard&rft.date=2009-08-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Conference+on+Optics+%2B+Photonics&rft.issn=&rft_id=info:doi/ L2 - http://spie.org/Documents/ConferencesExhibitions/OP09-final-program-L. pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-12-18 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Determining transmittance of a large surface laser system T2 - 2009 Conference on Optics + Photonics AN - 42294463; 5349982 JF - 2009 Conference on Optics + Photonics AU - Zhu, Shen Y1 - 2009/08/02/ PY - 2009 DA - 2009 Aug 02 KW - Lasers KW - Transmittance KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/42294463?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Conference+on+Optics+%2B+Photonics&rft.atitle=Determining+transmittance+of+a+large+surface+laser+system&rft.au=Zhu%2C+Shen&rft.aulast=Zhu&rft.aufirst=Shen&rft.date=2009-08-02&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Conference+on+Optics+%2B+Photonics&rft.issn=&rft_id=info:doi/ L2 - http://spie.org/Documents/ConferencesExhibitions/OP09-final-program-L. pdf LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-12-18 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Longitudinal decrements in iron status during military training in female soldiers. AN - 67560458; 19173765 AB - Fe is an essential micronutrient required for optimal cognitive and physical performance. Cross-sectional studies indicate that training degrades Fe status in female military personnel; however, longitudinal studies to measure the direct impact of military training on Fe status and performance have not been conducted. As such, the objective of the present study was to determine the longitudinal effects of military training on Fe status in female soldiers. Fe status was assessed in ninety-four female soldiers immediately before and following a 9-week basic combat training (BCT) course. Fe status indicators included Hb, erythrocyte distribution width (RDW), serum ferritin, transferrin saturation and soluble transferrin receptor (sTfR). A 2-mile (3.2 km) run test was performed at the end of BCT to assess aerobic performance. Fe status was affected by BCT, as all Fe status indicators, excluding Hb, were diminished (P < or = 0.01) at the end of BCT. Fe status indicators at the end of BCT (Hb and RDW) were associated (P < or = 0.05) with running performance, as was the change in sTfR over the training period (r 0.320; P < or = 0.05). In conclusion, Fe status in female soldiers is degraded during BCT, and degraded Fe status is associated with diminished aerobic performance. Female athletes and military personnel should strive to maintain Fe status to optimise physical performance. JF - The British journal of nutrition AU - McClung, James P AU - Karl, J Philip AU - Cable, Sonya J AU - Williams, Kelly W AU - Young, Andrew J AU - Lieberman, Harris R AD - Military Nutrition Division, US Army Research Institute of Environmental Medicine, Natick, MA 01760, USA. James.McClung@amedd.army.mil Y1 - 2009/08// PY - 2009 DA - August 2009 SP - 605 EP - 609 VL - 102 IS - 4 KW - Biomarkers KW - 0 KW - Receptors, Transferrin KW - Ferritins KW - 9007-73-2 KW - Index Medicus KW - Young Adult KW - Ferritins -- blood KW - Humans KW - Adult KW - Longitudinal Studies KW - Receptors, Transferrin -- blood KW - Biomarkers -- blood KW - Statistics, Nonparametric KW - Female KW - Anemia, Iron-Deficiency -- etiology KW - Occupational Diseases -- blood KW - Physical Endurance -- physiology KW - Military Personnel KW - Anemia, Iron-Deficiency -- physiopathology KW - Occupational Diseases -- etiology KW - Anemia, Iron-Deficiency -- blood KW - Occupational Diseases -- physiopathology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67560458?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+British+journal+of+nutrition&rft.atitle=Longitudinal+decrements+in+iron+status+during+military+training+in+female+soldiers.&rft.au=McClung%2C+James+P%3BKarl%2C+J+Philip%3BCable%2C+Sonya+J%3BWilliams%2C+Kelly+W%3BYoung%2C+Andrew+J%3BLieberman%2C+Harris+R&rft.aulast=McClung&rft.aufirst=James&rft.date=2009-08-01&rft.volume=102&rft.issue=4&rft.spage=605&rft.isbn=&rft.btitle=&rft.title=The+British+journal+of+nutrition&rft.issn=1475-2662&rft_id=info:doi/10.1017%2FS0007114509220873 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-09-11 N1 - Date created - 2009-08-07 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1017/S0007114509220873 ER - TY - JOUR T1 - A randomized, double-blind, safety and tolerability study to assess the ophthalmic and renal effects of tafenoquine 200 mg weekly versus placebo for 6 months in healthy volunteers. AN - 67528351; 19635898 AB - A randomized, double-blind, placebo-controlled study was conducted to assess the effect of tafenoquine, 200 mg weekly for 6 months on ophthalmic and renal safety. This trial was carried out after observations in previous clinical trials that tafenoquine may be associated with the development of corneal deposits and elevations in serum creatinine. In 120 healthy volunteers who received tafenoquine or placebo in a 2:1 randomization, there was no effect on night vision or other ophthalmic indices measured. Persons taking tafenoquine also showed no difference in mean change in glomerular filtration rate (GFR, mL/s/1.73 m(2)) after 6 months of dosing, with a treatment difference of -0.061 (95% confidence interval, -0.168, 0.045), and non-inferiority margin of -0.247 mL/s/1.73 m(2). Tafenoquine was well tolerated over the course of the study. The results of this study showed no clinically significant effects of tafenoquine on ophthalmic or renal function, and support its continued development as an antimalarial drug. JF - The American journal of tropical medicine and hygiene AU - Leary, Kevin J AU - Riel, Michael A AU - Roy, Michael J AU - Cantilena, Louis R AU - Bi, Daoqin AU - Brater, D Craig AU - van de Pol, Corina AU - Pruett, Khadeeja AU - Kerr, Caron AU - Veazey, James M AU - Beboso, Ronnie AU - Ohrt, Colin AD - United States Army Medical Materiel Development Activity, Fort Detrick, Maryland 21702-5009, USA. kevin.leary1@us.army.mil Y1 - 2009/08// PY - 2009 DA - August 2009 SP - 356 EP - 362 VL - 81 IS - 2 KW - Aminoquinolines KW - 0 KW - Antimalarials KW - tafenoquine KW - 262P8GS9L9 KW - Abridged Index Medicus KW - Index Medicus KW - Young Adult KW - Double-Blind Method KW - Humans KW - Adult KW - Middle Aged KW - Adolescent KW - Male KW - Female KW - Aminoquinolines -- adverse effects KW - Eye Diseases -- chemically induced KW - Antimalarials -- adverse effects KW - Night Vision -- drug effects KW - Kidney Diseases -- chemically induced UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67528351?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+American+journal+of+tropical+medicine+and+hygiene&rft.atitle=A+randomized%2C+double-blind%2C+safety+and+tolerability+study+to+assess+the+ophthalmic+and+renal+effects+of+tafenoquine+200+mg+weekly+versus+placebo+for+6+months+in+healthy+volunteers.&rft.au=Leary%2C+Kevin+J%3BRiel%2C+Michael+A%3BRoy%2C+Michael+J%3BCantilena%2C+Louis+R%3BBi%2C+Daoqin%3BBrater%2C+D+Craig%3Bvan+de+Pol%2C+Corina%3BPruett%2C+Khadeeja%3BKerr%2C+Caron%3BVeazey%2C+James+M%3BBeboso%2C+Ronnie%3BOhrt%2C+Colin&rft.aulast=Leary&rft.aufirst=Kevin&rft.date=2009-08-01&rft.volume=81&rft.issue=2&rft.spage=356&rft.isbn=&rft.btitle=&rft.title=The+American+journal+of+tropical+medicine+and+hygiene&rft.issn=1476-1645&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-08-21 N1 - Date created - 2009-07-28 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - TCEP treatment reduces proteolytic activity of BoNT/B in human neuronal SHSY-5Y cells. AN - 67509821; 19492407 AB - The light chain (LC) of botulinum neurotoxin B (BoNT/B) is unable to enter target neuronal cells by itself. It is brought into the cell in association with the BoNT/B heavy chain (HC) through endocytosis. The BoNT HC-LC subunits are held together by a single disulfide bond. Intracellular reduction of this bond and separation of the two subunits activates the endopeptidase activity of the LC. This requirement suggests a strategy to prevent uptake by prophylactic reduction to disrupt the disulfide bond prior to endocytosis of the complex. We examined the utility of tris-(2-carboxyethyl)-phosphine hydrochloride (TCEP), a relatively non-toxic, non-sulfur containing disulfide bond reducing agent that lacks the undesirable properties of mercapto-containing reducing agents. We found that TCEP was as effective as DTT with maximal LC endopeptidase activation occurring at 1 mM, a concentration not toxic to the human neuronal cell line, SHSY-5Y. In these cells, 1 mM TCEP maximally protected against BoNT/B inhibition of [(3)H]-NA release, achieving 72% of the release from un-intoxicated controls. This effect appears to be due to the sparing of SNARE proteins as the levels of VAMP-2, the specific target of BoNT/B, were protected. These results show that TCEP disrupts the structure of BoNT/B by reduction of the LC and HC bridging disulfide bond and prevents neuronal intoxication. Since disulfide bond coupling between toxin subunits is a general motif for many toxins, e.g., ricin, snake venom, and all BoNT serotypes, this suggests that TCEP is a promising means to protect against these toxins by preventing cell penetration. Published 2009 Wiley-Liss, Inc. JF - Journal of cellular biochemistry AU - Shi, Xuerong AU - Garcia, Gregory E AU - Neill, Roger J AU - Gordon, Richard K AD - Department of Regulated Laboratories, Division of Regulated Activities, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, Maryland 20910-7500, USA. xuerong.shi@amedd.army.mil Y1 - 2009/08/01/ PY - 2009 DA - 2009 Aug 01 SP - 1021 EP - 1030 VL - 107 IS - 5 KW - Disulfides KW - 0 KW - Phosphines KW - Protein Subunits KW - Vesicle-Associated Membrane Protein 2 KW - rimabotulinumtoxinB KW - 0Y70779M1F KW - tris(2-carboxyethyl)phosphine KW - 22OAC2MO2S KW - Botulinum Toxins KW - EC 3.4.24.69 KW - Botulinum Toxins, Type A KW - Norepinephrine KW - X4W3ENH1CV KW - Hydroxyurea KW - X6Q56QN5QC KW - Index Medicus KW - Oxidation-Reduction -- drug effects KW - Humans KW - Fluorescence Resonance Energy Transfer KW - Cell Line, Tumor KW - Hydroxyurea -- pharmacology KW - Protein Subunits -- metabolism KW - Disulfides -- metabolism KW - Protein Subunits -- chemistry KW - Vesicle-Associated Membrane Protein 2 -- metabolism KW - Cell Survival -- drug effects KW - Norepinephrine -- metabolism KW - Fluorometry KW - Protein Conformation KW - Protein Processing, Post-Translational -- drug effects KW - Phosphines -- pharmacology KW - Neurons -- metabolism KW - Neurons -- drug effects KW - Botulinum Toxins -- chemistry KW - Botulinum Toxins -- metabolism UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67509821?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+cellular+biochemistry&rft.atitle=TCEP+treatment+reduces+proteolytic+activity+of+BoNT%2FB+in+human+neuronal+SHSY-5Y+cells.&rft.au=Shi%2C+Xuerong%3BGarcia%2C+Gregory+E%3BNeill%2C+Roger+J%3BGordon%2C+Richard+K&rft.aulast=Shi&rft.aufirst=Xuerong&rft.date=2009-08-01&rft.volume=107&rft.issue=5&rft.spage=1021&rft.isbn=&rft.btitle=&rft.title=Journal+of+cellular+biochemistry&rft.issn=1097-4644&rft_id=info:doi/10.1002%2Fjcb.22205 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-10-13 N1 - Date created - 2009-07-22 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1002/jcb.22205 ER - TY - JOUR T1 - Identification and biochemical characterization of small-molecule inhibitors of Clostridium botulinum neurotoxin serotype A. AN - 67494669; 19528275 AB - An integrated strategy that combined in silico screening and tiered biochemical assays (enzymatic, in vitro, and ex vivo) was used to identify and characterize effective small-molecule inhibitors of Clostridium botulinum neurotoxin serotype A (BoNT/A). Virtual screening was initially performed by computationally docking compounds of the National Cancer Institute (NCI) database into the active site of BoNT/A light chain (LC). A total of 100 high-scoring compounds were evaluated in a high-performance liquid chromatography (HPLC)-based protease assay using recombinant full-length BoNT/A LC. Seven compounds that significantly inhibited the BoNT/A protease activity were selected. Database search queries of the best candidate hit [7-((4-nitro-anilino)(phenyl)methyl)-8-quinolinol (NSC 1010)] were performed to mine its nontoxic analogs. Fifty-five analogs of NSC 1010 were synthesized and examined by the HPLC-based assay. Of these, five quinolinol derivatives that potently inhibited both full-length BoNT/A LC and truncated BoNT/A LC (residues 1 to 425) were selected for further inhibition studies in neuroblastoma (N2a) cell-based and tissue-based mouse phrenic nerve hemidiaphragm assays. Consistent with enzymatic assays, in vitro and ex vivo studies revealed that these five quinolinol-based analogs effectively neutralized BoNT/A toxicity, with CB 7969312 exhibiting ex vivo protection at 0.5 microM. To date, this is the most potent BoNT/A small-molecule inhibitor that showed activity in an ex vivo assay. The reduced toxicity and high potency demonstrated by these five compounds at the biochemical, cellular, and tissue levels are distinctive among the BoNT/A small-molecule inhibitors reported thus far. This study demonstrates the utility of a multidisciplinary approach (in silico screening coupled with biochemical testing) for identifying promising small-molecule BoNT/A inhibitors. JF - Antimicrobial agents and chemotherapy AU - Roxas-Duncan, Virginia AU - Enyedy, Istvan AU - Montgomery, Vicki A AU - Eccard, Vanessa S AU - Carrington, Marco A AU - Lai, Huiguo AU - Gul, Nizamettin AU - Yang, David C H AU - Smith, Leonard A AD - Integrated Toxicology Division, U.S. Army Medical Research Institute of Infectious Diseases, 1425 Porter St., Fort Detrick, MD 21702, USA. Y1 - 2009/08// PY - 2009 DA - August 2009 SP - 3478 EP - 3486 VL - 53 IS - 8 KW - Antitoxins KW - 0 KW - Hydroxyquinolines KW - Botulinum Toxins, Type A KW - EC 3.4.24.69 KW - Index Medicus KW - Molecular Structure KW - Animals KW - In Vitro Techniques KW - Databases, Factual KW - Mice KW - Cell Line, Tumor KW - Female KW - Chromatography, High Pressure Liquid KW - Antitoxins -- pharmacology KW - Hydroxyquinolines -- chemical synthesis KW - Phrenic Nerve -- drug effects KW - Hydroxyquinolines -- chemistry KW - Hydroxyquinolines -- pharmacology KW - Botulinum Toxins, Type A -- metabolism KW - Botulinum Toxins, Type A -- genetics KW - Clostridium botulinum -- metabolism KW - Botulinum Toxins, Type A -- antagonists & inhibitors KW - Antitoxins -- chemistry UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67494669?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Antimicrobial+agents+and+chemotherapy&rft.atitle=Identification+and+biochemical+characterization+of+small-molecule+inhibitors+of+Clostridium+botulinum+neurotoxin+serotype+A.&rft.au=Roxas-Duncan%2C+Virginia%3BEnyedy%2C+Istvan%3BMontgomery%2C+Vicki+A%3BEccard%2C+Vanessa+S%3BCarrington%2C+Marco+A%3BLai%2C+Huiguo%3BGul%2C+Nizamettin%3BYang%2C+David+C+H%3BSmith%2C+Leonard+A&rft.aulast=Roxas-Duncan&rft.aufirst=Virginia&rft.date=2009-08-01&rft.volume=53&rft.issue=8&rft.spage=3478&rft.isbn=&rft.btitle=&rft.title=Antimicrobial+agents+and+chemotherapy&rft.issn=1098-6596&rft_id=info:doi/10.1128%2FAAC.00141-09 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-10-19 N1 - Date created - 2009-07-20 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: J Comput Aided Mol Des. 2001 May;15(5):411-28 [11394736] PLoS One. 2007;2(8):e761 [17712409] J Biol Chem. 2002 Sep 6;277(36):32815-9 [12089155] Toxicon. 2003 May;41(6):691-701 [12727273] Trends Mol Med. 2003 Jul;9(7):291-9 [12900216] Biochem Biophys Res Commun. 2003 Oct 10;310(1):84-93 [14511652] Arch Neurol. 2003 Dec;60(12):1685-91 [14676042] Proc Natl Acad Sci U S A. 2004 May 4;101(18):6888-93 [15107500] J Mol Graph Model. 2004 Mar;22(4):293-307 [15177081] J Pharmacol Exp Ther. 1983 Jan;224(1):135-40 [6294275] J Cell Biol. 1986 Aug;103(2):521-34 [3733877] J Cell Biol. 1986 Aug;103(2):535-44 [3015983] FEBS Lett. 1992 Nov 16;313(1):12-8 [1385218] J Pharmacol Exp Ther. 1993 Nov;267(2):720-7 [8246147] Eur J Biochem. 1994 Oct 1;225(1):263-70 [7925446] Semin Cell Biol. 1994 Aug;5(4):221-9 [7994006] Toxicon. 1995 Apr;33(4):551-7 [7570640] Q Rev Biophys. 1995 Nov;28(4):423-72 [8771234] J Protein Chem. 1997 Jan;16(1):19-26 [9055204] Toxicon. 1997 Mar;35(3):433-45 [9080598] Toxicon. 1997 Jul;35(7):1089-100 [9248007] Toxicon. 1997 Sep;35(9):1439-51 [9403967] FEBS Lett. 1998 Sep 11;435(1):61-4 [9755859] Nat Struct Biol. 1998 Oct;5(10):898-902 [9783750] Appl Microbiol. 1962 Jul;10:348-53 [13898066] Appl Microbiol. 1963 Jan;11:62-5 [13960592] Basic Clin Pharmacol Toxicol. 2004 Nov;95(5):215-9 [15546475] Bioorg Med Chem. 2005 Jan 17;13(2):333-41 [15598556] Nature. 2004 Dec 16;432(7019):925-9 [15592454] Bioorg Med Chem. 2006 Jan 15;14(2):395-408 [16203152] Protein Expr Purif. 2006 Apr;46(2):256-67 [16297638] Bioorg Med Chem Lett. 2007 Dec 1;17(23):6463-6 [17951059] Biochemistry. 2008 May 27;47(21):5736-45 [18457419] Bioorg Med Chem. 2009 Apr 15;17(8):3072-9 [19329331] J Appl Toxicol. 1999 Dec;19 Suppl 1:S29-33 [10594897] Science. 2000 Nov 17;290(5495):1273-4 [11185394] Org Lett. 2006 Apr 13;8(8):1729-32 [16597152] J Comb Chem. 2006 Jul-Aug;8(4):513-21 [16827563] Chem Commun (Camb). 2006 Aug 7;(29):3063-5 [16855686] Clin Infect Dis. 2006 Nov 15;43(10):1247-56 [17051488] J Biol Chem. 2007 Feb 16;282(7):5004-14 [17092934] Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2602-7 [17293454] Chem Biol. 2007 May;14(5):533-42 [17524984] J Chem Inf Comput Sci. 2001 May-Jun;41(3):702-12 [11410049] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1128/AAC.00141-09 ER - TY - JOUR T1 - Obesity and Cholesterol in Japanese, French, and U.S. Children AN - 57291963; 200921403 AB - The number of children at risk for overweight/obesity has increased dramatically in the last decade worldwide. This study compares measures of obesity (body mass index [BMI] and body fat percentage) and total cholesterol in 4,013 fourth-grade students from three countries, France, Japan, and the United States. Data were analyzed using t test, chi-square, and analysis of variance to determine differences between groups and by multiple linear regression. All variables differed significantly by group. BMI was highest in U.S. children. Body fat percentage was also highest in U.S. children and lowest in French children. Total cholesterol was highest in French children and lowest in U.S. White children. There were modest but significant associations between BMI and cholesterol in all groups except French children; associations varied by gender. Results indicate there was great variation in measures of obesity and cholesterol by country. The association between obesity and cholesterol may vary by culture, ethnicity, and gender. [Copyright Elsevier B.V.] JF - Journal of Pediatric Nursing AU - Bingham, Mona O AU - Harrell, Joanne S AU - Takada, Haruko AU - Washino, Kaei AU - Bradley, Chyrise AU - Berry, Diane AU - Park, Hyunju AU - Charles, Marie Aline AD - Brooke Army Medical Center, Fort Sam Houston, TX mona.bingham@us.army.mil Y1 - 2009/08// PY - 2009 DA - August 2009 SP - 314 EP - 322 PB - Elsevier Ltd, The Netherlands VL - 24 IS - 4 SN - 0882-5963, 0882-5963 KW - Body mass index Body fat percentage Cholesterol Overweight At risk for overweight Obesity Children KW - Obesity KW - Body fat KW - Body Mass Index KW - Cholesterol KW - Children KW - Japan KW - article UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/57291963?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aassia&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Pediatric+Nursing&rft.atitle=Obesity+and+Cholesterol+in+Japanese%2C+French%2C+and+U.S.+Children&rft.au=Bingham%2C+Mona+O%3BHarrell%2C+Joanne+S%3BTakada%2C+Haruko%3BWashino%2C+Kaei%3BBradley%2C+Chyrise%3BBerry%2C+Diane%3BPark%2C+Hyunju%3BCharles%2C+Marie+Aline&rft.aulast=Bingham&rft.aufirst=Mona&rft.date=2009-08-01&rft.volume=24&rft.issue=4&rft.spage=314&rft.isbn=&rft.btitle=&rft.title=Journal+of+Pediatric+Nursing&rft.issn=08825963&rft_id=info:doi/10.1016%2Fj.pedn.2008.01.002 LA - English DB - Applied Social Sciences Index & Abstracts (ASSIA) N1 - Date revised - 2009-08-31 N1 - Last updated - 2016-09-27 N1 - SubjectsTermNotLitGenreText - Children; Obesity; Cholesterol; Body Mass Index; Japan; Body fat DO - http://dx.doi.org/10.1016/j.pedn.2008.01.002 ER - TY - JOUR T1 - Sand dune movement in the Victoria Valley, Antarctica AN - 50147778; 2009-082286 AB - We use vertical aerial photographs and LiDAR topographic survey data to estimate dune migration rates in the Victoria Valley dunefield, Antarctica, between 1961 and 2001. Results confirm that the dunes migrated an average of 1.5 m/year. These values are consistent with other estimates of dune migration from cold climate deserts and are significantly lower than estimates from warm deserts. Dune migration rates are retarded by the presence of entrained ice, soil moisture and a reversing wind regime. Dune absorption, merging and limb extension are apparent from the time-series images and account for significant changes in dune form and the field-scale dune pattern. Dune-field pattern analysis shows an overall increase in dune-field organization with an increase in mean dune spacing and a reduction in total crest length and defect density. These data suggest that dunes in other cold desert environments on Earth, Mars or Titan, that may also have inter-bedded frozen laminae, still have the potential to migrate and organize, albeit at lower rates than dunes in warm deserts. JF - Geomorphology AU - Bourke, Mary C AU - Ewing, Ryan C AU - Finnegan, David AU - McGowan, Hamish A Y1 - 2009/08// PY - 2009 DA - August 2009 SP - 148 EP - 160 PB - Elsevier, Amsterdam VL - 109 IS - 3-4 SN - 0169-555X, 0169-555X KW - eolian features KW - dunes KW - laser methods KW - geophysical surveys KW - Mars KW - landforms KW - deserts KW - Victoria Valley KW - ice KW - sediments KW - climate KW - sand KW - patterns KW - sediment transport KW - clastic sediments KW - landform evolution KW - radar methods KW - morphometry KW - terrestrial planets KW - planets KW - Antarctica KW - lidar methods KW - surveys KW - aerial photography KW - wind transport KW - frozen ground KW - remote sensing KW - meltwater KW - 23:Geomorphology KW - 20:Applied geophysics UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50147778?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ageorefmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Geomorphology&rft.atitle=Sand+dune+movement+in+the+Victoria+Valley%2C+Antarctica&rft.au=Bourke%2C+Mary+C%3BEwing%2C+Ryan+C%3BFinnegan%2C+David%3BMcGowan%2C+Hamish+A&rft.aulast=Bourke&rft.aufirst=Mary&rft.date=2009-08-01&rft.volume=109&rft.issue=3-4&rft.spage=148&rft.isbn=&rft.btitle=&rft.title=Geomorphology&rft.issn=0169555X&rft_id=info:doi/10.1016%2Fj.geomorph.2009.02.028 L2 - http://www.sciencedirect.com/science/journal/0169555X LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. Reference includes data from CAPCAS, Elsevier Scientific Publishers, Amsterdam, Netherlands N1 - Date revised - 2009-01-01 N1 - SuppNotes - Based on Publisher-supplied data N1 - Last updated - 2012-06-07 N1 - SubjectsTermNotLitGenreText - aerial photography; Antarctica; clastic sediments; climate; deserts; dunes; eolian features; frozen ground; geophysical surveys; ice; landform evolution; landforms; laser methods; lidar methods; Mars; meltwater; morphometry; patterns; planets; radar methods; remote sensing; sand; sediment transport; sediments; surveys; terrestrial planets; Victoria Valley; wind transport DO - http://dx.doi.org/10.1016/j.geomorph.2009.02.028 ER - TY - JOUR T1 - Evaluation of Supa-Trac matting for expeditionary roads AN - 50118768; 2010-006543 JF - ERDC/GSL Technical Report AU - Rushing, Timothy W AU - Tingle, Jeb S AU - McCaffrey, Timothy J AU - Rushing, Todd S Y1 - 2009/08// PY - 2009 DA - August 2009 SP - 64 PB - U. S. Army Corps of Engineers, Engineer Research and Development Center, Geotechnical and Structures Laboratory, Vicksburg, MS KW - soil mechanics KW - sand KW - experimental studies KW - clastic sediments KW - silt KW - transportation KW - temperature KW - cold weather construction KW - laboratory studies KW - mud KW - sediments KW - construction KW - winter maintenance KW - roads KW - construction materials KW - 30:Engineering geology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/50118768?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/GeoRef&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=book&rft.jtitle=&rft.atitle=&rft.au=Rushing%2C+Timothy+W%3BTingle%2C+Jeb+S%3BMcCaffrey%2C+Timothy+J%3BRushing%2C+Todd+S&rft.aulast=Rushing&rft.aufirst=Timothy&rft.date=2009-08-01&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=Evaluation+of+Supa-Trac+matting+for+expeditionary+roads&rft.title=Evaluation+of+Supa-Trac+matting+for+expeditionary+roads&rft.issn=&rft_id=info:doi/ LA - English DB - GeoRef N1 - Copyright - GeoRef, Copyright 2012, American Geosciences Institute. N1 - Date revised - 2010-01-01 N1 - Number of references - 11 N1 - PubXState - MS N1 - Document feature - illus. incl. 4 tables N1 - Last updated - 2012-06-07 N1 - CODEN - #05760 N1 - SubjectsTermNotLitGenreText - clastic sediments; cold weather construction; construction; construction materials; experimental studies; laboratory studies; mud; roads; sand; sediments; silt; soil mechanics; temperature; transportation; winter maintenance ER - TY - CONF T1 - Experiment to characterize optical turbulence along a 2.33 km free-space laser path via differential image motion measurements AN - 21258274; 11271056 AB - In a previous experiment (Tunick, 2008: Optics Express 16, 14645-14654), values for the refractive index structure constant and the Fried parameter were calculated from measurements of signal intensity and angle-of-arrival statistics based on idealized models. Calculated turbulence parameters were evaluated in comparison to scintillometer-based measurements for several cases. It was found that the idealized models alone were insufficient to accurately describe complex, non-uniform microclimate and turbulence conditions. In addition, the signal intensity and focal spot displacement measurements were quite sensitive to platform and light source jitter. In order to compensate for adverse effects such as platform vibrations, an alternative differential image motion method is explored for optical turbulence parameter characterization. Hence, further experimental research is conducted along a 2.33 km free-space laser path to capture differential image centroid data from which Fried parameter and refractive index structure constant information can be obtained. This research is intended to provide useful information for US Army laser communications, long-range imaging and energy-on-target. JF - Proceedings of SPIE - The International Society for Optical Engineering AU - Tunick, Arnold Y1 - 2009/08// PY - 2009 DA - Aug 2009 PB - SPIE, P.O. BOX 10 Bellingham WA 98227-0010 USA VL - 7463 KW - Environment Abstracts; Environmental Engineering Abstracts KW - Article no. 746303 KW - experimental research KW - optics KW - microclimate KW - Turbulence KW - Conferences KW - Communications KW - Vibration KW - Lasers KW - Side effects KW - EE 20:Air Pollution: Monitoring, Control & Remediation KW - ENA 01:Air Pollution UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/21258274?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aenvabstractsmodule&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Proceedings+of+SPIE+-+The+International+Society+for+Optical+Engineering&rft.atitle=Experiment+to+characterize+optical+turbulence+along+a+2.33+km+free-space+laser+path+via+differential+image+motion+measurements&rft.au=Tunick%2C+Arnold&rft.aulast=Tunick&rft.aufirst=Arnold&rft.date=2009-08-01&rft.volume=7463&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=Proceedings+of+SPIE+-+The+International+Society+for+Optical+Engineering&rft.issn=0277786X&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-03-01 N1 - SuppNotes - Session: Optical Turbulence Characterization and Link Modeling: Joint Session with Conference 7464 N1 - Last updated - 2011-12-14 ER - TY - JOUR T1 - Locally-administered antibiotics in wounds in a limb AN - 20961882; 11054851 AB - We used a goat model of a contaminated musculoskeletal defect to determine the effectiveness of rapidly-resorbing calcium-sulphate pellets containing amikacin to reduce the local bacterial count. Our findings showed that this treatment eradicated the bacteria quickly, performed as well as standard polymethylmethacrylate mixed with an antibiotic and had many advantages over the latter. The pellets were prepared before surgery and absorbed completely. They released all of the antibiotic and did not require a subsequent operation for their removal. Our study indicated that locally administered antibiotics reduced bacteria within the wound rapidly. This method of treatment may have an important role in decreasing the rate of infection in contaminated wounds. JF - Journal of Bone and Joint Surgery (British) AU - Branstetter, J G AU - Jackson AU - Haggard, W O AU - Richelsoph, K C AU - Wenke, J C AD - 3400 Rawley East Chambers Avenue, San Antonio, Texas 78234, USA, Joseph.Wenke@us.army.mil Y1 - 2009/08// PY - 2009 DA - Aug 2009 SP - 1106 EP - 1109 VL - 91-B IS - 8 SN - 0301-620X, 0301-620X KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology; Calcium & Calcified Tissue Abstracts KW - Limbs KW - Amikacin KW - Bone surgery KW - Surgery KW - Antibiotics KW - polymethylmethacrylate KW - Infection KW - Wounds KW - Models KW - A 01340:Antibiotics & Antimicrobials KW - J 02490:Miscellaneous KW - T 2025:Bone and Bone Diseases UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20961882?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Bone+and+Joint+Surgery+%28British%29&rft.atitle=Locally-administered+antibiotics+in+wounds+in+a+limb&rft.au=Branstetter%2C+J+G%3BJackson%3BHaggard%2C+W+O%3BRichelsoph%2C+K+C%3BWenke%2C+J+C&rft.aulast=Branstetter&rft.aufirst=J&rft.date=2009-08-01&rft.volume=91-B&rft.issue=8&rft.spage=1106&rft.isbn=&rft.btitle=&rft.title=Journal+of+Bone+and+Joint+Surgery+%28British%29&rft.issn=0301620X&rft_id=info:doi/10.1302%2F0301-620X.91B8.22216 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-10-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Limbs; Amikacin; Bone surgery; Surgery; Antibiotics; Infection; polymethylmethacrylate; Models; Wounds DO - http://dx.doi.org/10.1302/0301-620X.91B8.22216 ER - TY - JOUR T1 - Workshop Report: Modeling the Molecular Mechanism of Bacterial Spore Germination and Elucidating Reasons for Germination Heterogeneity AN - 20784541; 10841678 AB - Over the course of 2 days, top researchers in the fields of bacterial spore biology and computational biology discussed approaches to determine the cause of spore germination heterogeneity. Biological and mathematical data gaps were identified, and experimental approaches and computational strategies for modeling spore germination were presented and evaluated. As a result of these interactions, future research directions were defined, the outcome of which should result in a robust model to help define the molecular mechanism(s) of spore germination. Mechanistic understanding of germination will be instrumental for developing novel sterilization, treatment, and decontamination strategies to mitigate threats posed by spores. JF - Journal of Food Science AU - Indest, Karl J AU - Buchholz, Wallace G AU - Faeder, Jim R AU - Setlow, Peter AD - Life Sciences Div., U.S. Army Research Office, 4300 S. Miami Blvd, Durham, NC 27703, U.S.A., wallace.buchholz@us.army.mil Y1 - 2009/08// PY - 2009 DA - Aug 2009 SP - R73 EP - R78 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 USA VL - 74 IS - 6 SN - 0022-1147, 0022-1147 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology KW - Bacteria KW - Molecular modelling KW - Mathematical models KW - Data processing KW - Conferences KW - Spore germination KW - Decontamination KW - Computer applications KW - Sterilization KW - J 02320:Cell Biology KW - A 01330:Food Microbiology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20784541?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Food+Science&rft.atitle=Workshop+Report%3A+Modeling+the+Molecular+Mechanism+of+Bacterial+Spore+Germination+and+Elucidating+Reasons+for+Germination+Heterogeneity&rft.au=Indest%2C+Karl+J%3BBuchholz%2C+Wallace+G%3BFaeder%2C+Jim+R%3BSetlow%2C+Peter&rft.aulast=Indest&rft.aufirst=Karl&rft.date=2009-08-01&rft.volume=74&rft.issue=6&rft.spage=R73&rft.isbn=&rft.btitle=&rft.title=Journal+of+Food+Science&rft.issn=00221147&rft_id=info:doi/10.1111%2Fj.1750-3841.2009.01245.x LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-09-01 N1 - Last updated - 2012-03-29 N1 - SubjectsTermNotLitGenreText - Molecular modelling; Data processing; Mathematical models; Conferences; Spore germination; Decontamination; Computer applications; Sterilization; Bacteria DO - http://dx.doi.org/10.1111/j.1750-3841.2009.01245.x ER - TY - JOUR T1 - Translocation of ricin across polarized human bronchial epithelial cells AN - 20618263; 9333671 AB - Due to widespread availability, toxicity, and potential for use as a bioterrorism agent, ricin is classified as a category B select agent. While ricin can be internalized by a number of routes, inhalation is particularly problematic. The resulting damage leads to irreversible pulmonary edema and death. Our study describes a model system developed to investigate the effects of ricin on respiratory epithelium. Human bronchial epithelial (HBE) cells were cultured on collagen IV-coated inserts until polarized epithelial cell monolayers developed. Ricin was added to the apical or basal medium and damage to the cell monolayer was then assessed. Within a few hours after exposure, the cell monolayer was permeable to paracellular passage of the toxin. A mouse anti-ricin antibody neutralized ricin and prevented cellular damage as long as the antibody was present before the addition of toxin. These studies suggested that effective therapeutic agents or antibodies neutralizing ricin biological activity must be present at the apical surface of epithelial cells. The in vitro system developed here provides a method by which to screen potential therapeutics for protecting lung epithelial cells against ricin intoxication. JF - Toxicon AU - Rushing AU - Saylor, M L AU - Hale, M L AD - Integrated Toxicology Division, 1425 Porter St., Fort Detrick, MD 21702, USA, martha.hale@amedd.army.mil Y1 - 2009/08// PY - 2009 DA - Aug 2009 SP - 184 EP - 191 PB - Elsevier Science, P.O. Box 800 Kidlington Oxford OX5 1DX UK, [mailto:nlinfo-f@elsevier.nl], [URL:http://www.elsevier.nl] VL - 54 IS - 2 SN - 0041-0101, 0041-0101 KW - Toxicology Abstracts KW - Inhalation KW - Intoxication KW - Epithelial cells KW - bioterrorism KW - Ricin KW - Edema KW - Toxicity KW - Toxins KW - Collagen KW - Antibodies KW - Lung KW - Translocation KW - Respiratory tract KW - X 24370:Natural Toxins UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20618263?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Toxicon&rft.atitle=Translocation+of+ricin+across+polarized+human+bronchial+epithelial+cells&rft.au=Rushing%3BSaylor%2C+M+L%3BHale%2C+M+L&rft.aulast=Rushing&rft.aufirst=&rft.date=2009-08-01&rft.volume=54&rft.issue=2&rft.spage=184&rft.isbn=&rft.btitle=&rft.title=Toxicon&rft.issn=00410101&rft_id=info:doi/10.1016%2Fj.toxicon.2009.04.003 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-06-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Intoxication; Inhalation; Epithelial cells; bioterrorism; Ricin; Edema; Toxicity; Toxins; Collagen; Antibodies; Lung; Translocation; Respiratory tract DO - http://dx.doi.org/10.1016/j.toxicon.2009.04.003 ER - TY - JOUR T1 - Sequence signatures in envelope protein may determine whether flaviviruses produce hemorrhagic or encephalitic syndromes AN - 20099723; 10231222 AB - We analyzed the envelope proteins in pathogenic flaviviruses to determine whether there are sequence signatures associated with the tendency of viruses to produce hemorrhagic disease (H-viruses) or encephalitis (E-viruses). We found that, at the position corresponding to the glycosylated Asn-67 in dengue virus, asparagine (Asn) occurs in all seven viral species that cause hemorrhagic disease in humans. Furthermore, Asn was extremely rare at position 67 in six flaviviruses that cause encephalitis, being replaced by Asp in four of them. Of the 3,246 sequences from H- and E-viruses, we found that 2,916 sequences (90%) contained Asn in position 67 for H-viruses or Asp in position 67 for E-viruses. The change from Asn-67 that is prevalent in H-viruses to Asp-67 (common in E-viruses) contributes to a stronger electrostatically negative surface in the E-viruses as compared to the H-viruses. These findings should help predicting the disease potential of emerging and re-emerging flaviviruses and understanding the relationship between protein structure and disease outcome. JF - Virus Genes AU - Barker, Winona C AU - Mazumder, Raja AU - Vasudevan, Sona AU - Sagripanti, Jose-Luis AU - Wu, Cathy H Y1 - 2009/08// PY - 2009 DA - August 2009 SP - 1 EP - 9 PB - Springer-Verlag, Tiergartenstrasse 17 Heidelberg 69121 Germany VL - 39 IS - 1 SN - 0920-8569, 0920-8569 KW - ASFA 3: Aquatic Pollution & Environmental Quality; ASFA 1: Biological Sciences & Living Resources; CSA Neurosciences Abstracts; Virology & AIDS Abstracts; Genetics Abstracts KW - Dengue virus KW - Symptoms KW - Human diseases KW - Viruses KW - Environmental impact KW - Hemorrhage KW - Asparagine KW - Encephalitis KW - Public health KW - Protein structure KW - Envelope protein KW - Proteins KW - Hemorrhagic disease KW - G 07880:Human Genetics KW - N3 11023:Neurogenetics KW - Q1 08563:Fishing gear and methods KW - Q5 08524:Public health, medicines, dangerous organisms KW - V 22310:Genetics, Taxonomy & Structure UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20099723?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aasfaaquaticpollution&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Virus+Genes&rft.atitle=Sequence+signatures+in+envelope+protein+may+determine+whether+flaviviruses+produce+hemorrhagic+or+encephalitic+syndromes&rft.au=Barker%2C+Winona+C%3BMazumder%2C+Raja%3BVasudevan%2C+Sona%3BSagripanti%2C+Jose-Luis%3BWu%2C+Cathy+H&rft.aulast=Barker&rft.aufirst=Winona&rft.date=2009-08-01&rft.volume=39&rft.issue=1&rft.spage=1&rft.isbn=&rft.btitle=&rft.title=Virus+Genes&rft.issn=09208569&rft_id=info:doi/10.1007%2Fs11262-009-0343-4 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-07-01 N1 - Last updated - 2016-12-22 N1 - SubjectsTermNotLitGenreText - Symptoms; Human diseases; Viruses; Environmental impact; Proteins; Public health; Protein structure; Envelope protein; Hemorrhagic disease; Hemorrhage; Asparagine; Encephalitis; Dengue virus DO - http://dx.doi.org/10.1007/s11262-009-0343-4 ER - TY - JOUR T1 - Real-time PCR for the early detection and quantification of Coxiella burnetii as an alternative to the murine bioassay AN - 20072899; 10073656 AB - Real-time PCR was used to analyze archived blood from non-human primates (NHP) and fluid samples originating from a well-controlled Q fever vaccine efficacy trial. The PCR targets were the IS1111 element and the com1 gene of Coxiella burnetii. Data from that previous study were used to evaluate real-time PCR as an alternative to the use of sero-conversion by mouse bioassay for both quantification and early detection of C. burnetii bacteria. Real-time PCR and the mouse bioassay exhibited no statistical difference in quantifying the number of microorganisms delivered in the aerosol challenge dose. The presence of C. burnetii in peripheral blood of non-human primates was detected by real-time PCR as early after exposure as the mouse bioassay with results available within hours instead of weeks. This study demonstrates that real-time PCR has the ability to replace the mouse bioassay to measure dosage and monitor infection of C. burnetii in a non-human primate model. JF - Molecular and Cellular Probes AU - Howe, Gerald B AU - Loveless, Bonnie M AU - Norwood, David AU - Craw, Philip AU - Waag, David AU - England, Marilyn AU - Lowe, John R AU - Courtney, Bernard C AU - Pitt, MLouise AU - Kulesh, David A AD - Diagnostic Systems Division, United States Army Medical Research Institute for Infectious Diseases, 1425 Porter St, Frederick, MD 21702, USA, david.kulesh@amedd.army.mil Y1 - 2009/08// PY - 2009 DA - Aug 2009 SP - 127 EP - 131 PB - Elsevier Science, The Boulevard Langford Lane Kidlington Oxford OX5 1GB UK, [mailto:usinfo-f@elsevier.com], [URL:http://www.elsevier.nl] VL - 23 IS - 3-4 SN - 0890-8508, 0890-8508 KW - Microbiology Abstracts A: Industrial & Applied Microbiology; Microbiology Abstracts B: Bacteriology KW - Coxiella burnetii KW - Q fever KW - Real-time PCR KW - Non-human primates KW - Aerosol challenge KW - Mouse bioassay KW - Aerosols KW - Statistics KW - Data processing KW - Animal models KW - Probes KW - COM1 gene KW - Peripheral blood KW - Infection KW - Primates KW - Microorganisms KW - Polymerase chain reaction KW - Vaccines KW - J 02310:Genetics & Taxonomy KW - A 01300:Methods UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/20072899?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Amicrobiologyb&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Molecular+and+Cellular+Probes&rft.atitle=Real-time+PCR+for+the+early+detection+and+quantification+of+Coxiella+burnetii+as+an+alternative+to+the+murine+bioassay&rft.au=Howe%2C+Gerald+B%3BLoveless%2C+Bonnie+M%3BNorwood%2C+David%3BCraw%2C+Philip%3BWaag%2C+David%3BEngland%2C+Marilyn%3BLowe%2C+John+R%3BCourtney%2C+Bernard+C%3BPitt%2C+MLouise%3BKulesh%2C+David+A&rft.aulast=Howe&rft.aufirst=Gerald&rft.date=2009-08-01&rft.volume=23&rft.issue=3-4&rft.spage=127&rft.isbn=&rft.btitle=&rft.title=Molecular+and+Cellular+Probes&rft.issn=08908508&rft_id=info:doi/10.1016%2Fj.mcp.2009.01.004 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-07-01 N1 - Last updated - 2015-03-30 N1 - SubjectsTermNotLitGenreText - Aerosols; Data processing; Statistics; Probes; Microorganisms; Animal models; COM1 gene; Polymerase chain reaction; Peripheral blood; Vaccines; Infection; Q fever; Coxiella burnetii; Primates DO - http://dx.doi.org/10.1016/j.mcp.2009.01.004 ER - TY - JOUR T1 - cExternal beam radiation results in minimal changes in post void residual urine volumes during the treatment of clinically localized prostate cancer. AN - 67564697; 19624852 AB - To evaluate the impact of external beam radiation therapy (XRT) on weekly ultrasound determined post-void residual (PVR) urine volumes in patients with prostate cancer. 125 patients received XRT for clinically localized prostate cancer. XRT was delivered to the prostate only (n = 66) or if the risk of lymph node involvement was greater than 10% to the whole pelvis followed by a prostate boost (n = 59). All patients were irradiated in the prone position in a custom hip-fix mobilization device with an empty bladder and rectum. PVR was obtained at baseline and weekly. Multiple clinical and treatment parameters were evaluated as predictors for weekly PVR changes. The mean patient age was 73.9 years with a mean pre-treatment prostate volume of 53.3 cc, a mean IPSS of 11.3 and a mean baseline PVR of 57.6 cc. During treatment, PVR decreased from baseline in both cohorts with the absolute difference within the limits of accuracy of the bladder scanner. Alpha-blockers did not predict for a lower PVR during treatment. There was no significant difference in mean PVR urine volumes or differences from baseline in either the prostate only or pelvic radiation groups (p = 0.664 and p = 0.458, respectively). Patients with a larger baseline PVR (>40 cc) had a greater reduction in PVR, although the greatest reduction was seen between weeks one and three. Patients with a small PVR (<40 cc) had no demonstrable change throughout treatment. Prostate XRT results in clinically insignificant changes in weekly PVR volumes, suggesting that radiation induced bladder irritation does not substantially influence bladder residual urine volumes. JF - Radiation oncology (London, England) AU - Orio, Peter F AU - Merrick, Gregory S AU - Allen, Zachariah A AU - Butler, Wayne M AU - Wallner, Kent E AU - Kurko, Brian S AU - Galbreath, Robert W AD - Brooke Army Medical Center Department of Radiation Oncology, Ft. Sam, Houston, TX 78234, USA. peter.orio@us.army.mil Y1 - 2009/07/22/ PY - 2009 DA - 2009 Jul 22 SP - 26 VL - 4 KW - Index Medicus KW - Urodynamics KW - Humans KW - Aged KW - Male KW - Radiotherapy -- adverse effects KW - Urination -- radiation effects KW - Urinary Bladder -- radiation effects KW - Prostatic Neoplasms -- radiotherapy UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67564697?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Radiation+oncology+%28London%2C+England%29&rft.atitle=cExternal+beam+radiation+results+in+minimal+changes+in+post+void+residual+urine+volumes+during+the+treatment+of+clinically+localized+prostate+cancer.&rft.au=Orio%2C+Peter+F%3BMerrick%2C+Gregory+S%3BAllen%2C+Zachariah+A%3BButler%2C+Wayne+M%3BWallner%2C+Kent+E%3BKurko%2C+Brian+S%3BGalbreath%2C+Robert+W&rft.aulast=Orio&rft.aufirst=Peter&rft.date=2009-07-22&rft.volume=4&rft.issue=&rft.spage=26&rft.isbn=&rft.btitle=&rft.title=Radiation+oncology+%28London%2C+England%29&rft.issn=1748-717X&rft_id=info:doi/10.1186%2F1748-717X-4-26 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-10-27 N1 - Date created - 2009-08-07 N1 - Date revised - 2017-01-13 N1 - SuppNotes - Cited By: Int J Radiat Oncol Biol Phys. 2000 Jun 1;47(3):655-60 [10837948] Int J Radiat Oncol Biol Phys. 2005 Mar 1;61(3):933-7 [15708277] Urology. 2001 Dec;58(6):843-8 [11744442] Urology. 2003 Oct;62(4):656-60 [14550437] Radiother Oncol. 2004 Jan;70(1):37-44 [15036850] Int J Radiat Oncol Biol Phys. 1991 Jun;20(6):1317-24 [2045306] Med Dosim. 1993 Spring;18(1):13-5 [8507354] Radiother Oncol. 1995 Oct;37(1):35-42 [8539455] Int J Radiat Oncol Biol Phys. 1996 Jan 15;34(2):451-8 [8567348] Int J Radiat Oncol Biol Phys. 1997 Apr 1;38(1):73-81 [9212007] Int J Radiat Oncol Biol Phys. 1998 Jun 1;41(3):491-500 [9635694] Int J Radiat Oncol Biol Phys. 1998 Oct 1;42(3):661-72 [9806528] Int J Radiat Oncol Biol Phys. 1999 Mar 1;43(4):719-25 [10098426] Radiother Oncol. 1999 Feb;50(2):225-34 [10368047] Int J Radiat Oncol Biol Phys. 2005 Jun 1;62(2):406-17 [15890582] JAMA. 2005 Sep 14;294(10):1233-9 [16160131] Int J Radiat Oncol Biol Phys. 2006 Mar 1;64(3):856-61 [16243443] Int J Radiat Oncol Biol Phys. 2006 Jun 1;65(2):371-7 [16542790] Radiother Oncol. 2006 Jun;79(3):335-40 [16781790] Semin Radiat Oncol. 2008 Jan;18(1):58-66 [18082589] Int J Radiat Oncol Biol Phys. 2008 Jan 1;70(1):67-74 [17765406] Radiother Oncol. 2008 Nov;89(2):172-9 [18703248] J Clin Oncol. 2000 Dec 1;18(23):3904-11 [11099319] N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1186/1748-717X-4-26 ER - TY - JOUR T1 - Production of catalytically inactive BoNT/A1 holoprotein and comparison with BoNT/A1 subunit vaccines against toxin subtypes A1, A2, and A3. AN - 67445833; 19450643 AB - A recombinant, catalytically inactive Clostridium botulinum neurotoxin A1 holoprotein (ciBoNT/A1 HP) was constructed by introducing amino acid substitutions H223A, E224A, and H227A in the active site to ablate proteolytic activity. ciBoNT/A1 HP was produced in the yeast Pichia pastoris and the purified product was evaluated as a vaccine candidate by comparison against recombinant BoNT/A1 LC, LC-belt, LC-H(n), and H(c) antigens and a LC-H(n)+H(c) combination in mouse potency and efficacy bioassays when challenged with BoNT/A subtypes /A1, /A2, and /A3. A single dose of ciBoNT/A1 HP provided equivalent or greater protective immunity, not only against the homologous toxin, but also against two distinct toxin subtypes with significant amino acid divergence. Only the LC-H(n)+H(c) combination provided comparable protection against /A1; however, it was less effective against subtypes /A2 and /A3. Differences in protective immunity diminished after multiple vaccinations with either ciBoNT/A1 HP or BoNT/A1 H(c), and the survival rates were more comparable at the toxin levels used to challenge. JF - Vaccine AU - Webb, Robert P AU - Smith, Theresa J AU - Wright, Patrick AU - Brown, Jennifer AU - Smith, Leonard A AD - United States Army Medical Research Institute for Infectious Diseases, 1425 Porter Street, Frederick, MD 21702, United States. Y1 - 2009/07/16/ PY - 2009 DA - 2009 Jul 16 SP - 4490 EP - 4497 VL - 27 IS - 33 KW - Bacterial Vaccines KW - 0 KW - Recombinant Proteins KW - Vaccines, Subunit KW - Botulinum Toxins, Type A KW - EC 3.4.24.69 KW - Index Medicus KW - Recombinant Proteins -- isolation & purification KW - Animals KW - Recombinant Proteins -- biosynthesis KW - Protein Stability KW - Recombinant Proteins -- immunology KW - Pichia -- metabolism KW - Lethal Dose 50 KW - Clostridium botulinum -- immunology KW - Mice KW - Vaccines, Subunit -- immunology KW - Botulinum Toxins, Type A -- isolation & purification KW - Bacterial Vaccines -- immunology KW - Botulism -- prevention & control KW - Botulism -- immunology KW - Botulinum Toxins, Type A -- biosynthesis KW - Botulinum Toxins, Type A -- immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67445833?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Vaccine&rft.atitle=Production+of+catalytically+inactive+BoNT%2FA1+holoprotein+and+comparison+with+BoNT%2FA1+subunit+vaccines+against+toxin+subtypes+A1%2C+A2%2C+and+A3.&rft.au=Webb%2C+Robert+P%3BSmith%2C+Theresa+J%3BWright%2C+Patrick%3BBrown%2C+Jennifer%3BSmith%2C+Leonard+A&rft.aulast=Webb&rft.aufirst=Robert&rft.date=2009-07-16&rft.volume=27&rft.issue=33&rft.spage=4490&rft.isbn=&rft.btitle=&rft.title=Vaccine&rft.issn=1873-2518&rft_id=info:doi/10.1016%2Fj.vaccine.2009.05.030 LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-08-13 N1 - Date created - 2009-07-03 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1016/j.vaccine.2009.05.030 ER - TY - CPAPER T1 - The Group Radicalization Assessment Scale: Evaluating the spread of Salafi Jihadist ideology T2 - 2009 Annual Scientific Meeting of the International Society of Political Psychology (ISPP 2009) AN - 40354844; 5279076 JF - 2009 Annual Scientific Meeting of the International Society of Political Psychology (ISPP 2009) AU - Richard, Philip-Daniel Y1 - 2009/07/14/ PY - 2009 DA - 2009 Jul 14 KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40354844?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Annual+Scientific+Meeting+of+the+International+Society+of+Political+Psychology+%28ISPP+2009%29&rft.atitle=The+Group+Radicalization+Assessment+Scale%3A+Evaluating+the+spread+of+Salafi+Jihadist+ideology&rft.au=Richard%2C+Philip-Daniel&rft.aulast=Richard&rft.aufirst=Philip-Daniel&rft.date=2009-07-14&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Annual+Scientific+Meeting+of+the+International+Society+of+Political+Psychology+%28ISPP+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://ispp.org/annual_meeting_archives/2009conf/2009DublinConference. html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-09-28 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - In Their Place: Measuring Gender Attitudes and Social Dominance Orientation among U.S. Army Personnel T2 - 2009 Annual Scientific Meeting of the International Society of Political Psychology (ISPP 2009) AN - 40349178; 5278849 JF - 2009 Annual Scientific Meeting of the International Society of Political Psychology (ISPP 2009) AU - Ryan, Diane Y1 - 2009/07/14/ PY - 2009 DA - 2009 Jul 14 KW - USA KW - Attitudes KW - Sex KW - Military KW - Dominance KW - Personnel KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40349178?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Annual+Scientific+Meeting+of+the+International+Society+of+Political+Psychology+%28ISPP+2009%29&rft.atitle=In+Their+Place%3A+Measuring+Gender+Attitudes+and+Social+Dominance+Orientation+among+U.S.+Army+Personnel&rft.au=Ryan%2C+Diane&rft.aulast=Ryan&rft.aufirst=Diane&rft.date=2009-07-14&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Annual+Scientific+Meeting+of+the+International+Society+of+Political+Psychology+%28ISPP+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://ispp.org/annual_meeting_archives/2009conf/2009DublinConference. html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-09-28 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Electrolytic Redox and Electrochemical Generated Alkaline Hydrolysis of Hexahydro-1,3,5-trinitro-1,3,5 triazine (RDX) in Sand Columns AN - 754543601; 13267805 AB - Sand-packed horizontal flow columns (5 cm i.d. X 65 cm) were used in laboratory experiments to simulate in situ electrolytic and alkaline hybrid treatment zone for aqueous phase decomposition of RDX. An upgradient cathode and downgradient anode, spaced 35 cm apart, were used to create alkaline reducing conditions followed by oxic, acidic conditions to degrade RDX by combination of alkaline hydrolysis and direct electrolysis. A preliminary experiment (25 mg/L RDX influent) with seepage velocity of 30.5 cm/day and current density of 9.9 A/m2 was used to determine the treatment feasibility and the aqueous products of RDX decomposition. Three additional column experiments (0.5 mg/L RDX influent) under the same conditions as the preliminary column were used to observe the treatment process repeatability and the alkaline treatment zone development. The results demonstrated approximately 95% decomposition of RDX in the column with an applied current density of 9.9 A/m2. Aqueous end-products formate, nitrite, and nitrate were detected in the effluent. Approximately 75% of the RDX was destroyed near the cathode, presumably by electrolysis, with 23% decomposed downstream of the cathode by alkaline hydrolysis. The preliminary column pseudo first order alkaline hydrolysis rate coefficient of 1 0.7 X 10-3 min-1 was used to estimate a treatment zone length less than 100 cm for RDX treatment below the EPA drinking water lifetime health advisory of 0.002 mg/L. JF - Environmental Science & Technology AU - Gent, David B AU - Wani, Altaf H AU - Davis, Jeffrey L AU - Alshawabkeh, Akram AD - Environmental Laboratory, U.S. Army Engineer Research and Development Center, 3909 Halls Ferry Road, Vicksburg, Mississippi 39180, Environmental Resources Management (ERM), 15810 Park Ten Place, Suite 300, Houston, Texas 77084, and Department of Civil and Environmental Engineering, Northeastern University, 360 Huntington Avenue, Boston, Massachusetts 02115 Y1 - 2009/07/13/ PY - 2009 DA - 2009 Jul 13 SP - 6301 EP - 6307 PB - American Chemical Society, 1155 16th St., NW Washington DC 20036 USA VL - 43 IS - 16 SN - 0013-936X, 0013-936X KW - ASFA 3: Aquatic Pollution & Environmental Quality; Pollution Abstracts; Environment Abstracts; Aqualine Abstracts; Water Resources Abstracts KW - Feasibility studies KW - Cathodes KW - Degradation KW - Decomposition KW - Drinking Water KW - Downstream KW - Seepages KW - Pollution detection KW - Nitrates KW - Laboratory testing KW - Density KW - Laboratories KW - Velocity KW - influents KW - Influents KW - Effluents KW - Hydrolysis KW - EPA KW - hybrids KW - Nitrites KW - downstream KW - seepages KW - Electrolysis KW - Drinking water KW - Electrochemistry KW - Q5 08503:Characteristics, behavior and fate KW - SW 3040:Wastewater treatment processes KW - P 2000:FRESHWATER POLLUTION KW - ENA 16:Renewable Resources-Water KW - AQ 00002:Water Quality UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/754543601?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aaqualine&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Environmental+Science+%26+Technology&rft.atitle=Electrolytic+Redox+and+Electrochemical+Generated+Alkaline+Hydrolysis+of+Hexahydro-1%2C3%2C5-trinitro-1%2C3%2C5+triazine+%28RDX%29+in+Sand+Columns&rft.au=Gent%2C+David+B%3BWani%2C+Altaf+H%3BDavis%2C+Jeffrey+L%3BAlshawabkeh%2C+Akram&rft.aulast=Gent&rft.aufirst=David&rft.date=2009-07-13&rft.volume=43&rft.issue=16&rft.spage=6301&rft.isbn=&rft.btitle=&rft.title=Environmental+Science+%26+Technology&rft.issn=0013936X&rft_id=info:doi/10.1021%2Fes803567s L2 - http://pubs.acs.org/doi/abs/10.1021/es803567s LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-08-01 N1 - Last updated - 2016-02-04 N1 - SubjectsTermNotLitGenreText - Cathodes; Pollution detection; Drinking Water; Degradation; Electrolysis; Seepages; Effluents; Influents; Hydrolysis; Feasibility studies; Laboratory testing; Nitrates; Velocity; influents; Decomposition; EPA; hybrids; Nitrites; downstream; seepages; Electrochemistry; Drinking water; Laboratories; Density; Downstream DO - http://dx.doi.org/10.1021/es803567s ER - TY - CPAPER T1 - Optimal Stopping Games for Stochastic Systems with Memory T2 - 2009 Conference of the Society for Industrial and Applied Mathematics on Control and its Applications (CT09) AN - 40274124; 5227230 JF - 2009 Conference of the Society for Industrial and Applied Mathematics on Control and its Applications (CT09) AU - Chang, Mou-Hsiung Y1 - 2009/07/06/ PY - 2009 DA - 2009 Jul 06 KW - Stochasticity KW - Memory KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40274124?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Conference+of+the+Society+for+Industrial+and+Applied+Mathematics+on+Control+and+its+Applications+%28CT09%29&rft.atitle=Optimal+Stopping+Games+for+Stochastic+Systems+with+Memory&rft.au=Chang%2C+Mou-Hsiung&rft.aulast=Chang&rft.aufirst=Mou-Hsiung&rft.date=2009-07-06&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Conference+of+the+Society+for+Industrial+and+Applied+Mathematics+on+Control+and+its+Applications+%28CT09%29&rft.issn=&rft_id=info:doi/ L2 - http://meetings.siam.org/program.cfm?CONFCODE=CT09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-09-28 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - An End to End Life Cycle for ISR in Coalition Networks T2 - 12th Conference of the International Society of Information Fusion (FUSION 2009) AN - 40262725; 5226448 JF - 12th Conference of the International Society of Information Fusion (FUSION 2009) AU - Cirincione, Gregory AU - Verma, Dinesh AU - Pham, Tien AU - Pearson, Gavin Y1 - 2009/07/06/ PY - 2009 DA - 2009 Jul 06 KW - Life cycle KW - U 2000:Biological Sciences UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40262725?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=12th+Conference+of+the+International+Society+of+Information+Fusion+%28FUSION+2009%29&rft.atitle=An+End+to+End+Life+Cycle+for+ISR+in+Coalition+Networks&rft.au=Cirincione%2C+Gregory%3BVerma%2C+Dinesh%3BPham%2C+Tien%3BPearson%2C+Gavin&rft.aulast=Cirincione&rft.aufirst=Gregory&rft.date=2009-07-06&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=12th+Conference+of+the+International+Society+of+Information+Fusion+%28FUSION+2009%29&rft.issn=&rft_id=info:doi/ L2 - http://controls.papercept.net/conferences/conferences/FUSION09/program /FUSION09_ProgramAtAGlanceWeb.html LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-09-28 N1 - Last updated - 2010-05-03 ER - TY - CPAPER T1 - Oscillatory Behavior of a Spatial Soliton in a Power Law Medium T2 - 2009 Annual Meeting of the Society for Industrial and Applied Mathematics AN - 40250561; 5215097 JF - 2009 Annual Meeting of the Society for Industrial and Applied Mathematics AU - Crutcher, Sihon AU - Osei, Albert Y1 - 2009/07/06/ PY - 2009 DA - 2009 Jul 06 KW - Solitons KW - U 7000:Multidisciplinary UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/40250561?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acpi&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=conference&rft.jtitle=2009+Annual+Meeting+of+the+Society+for+Industrial+and+Applied+Mathematics&rft.atitle=Oscillatory+Behavior+of+a+Spatial+Soliton+in+a+Power+Law+Medium&rft.au=Crutcher%2C+Sihon%3BOsei%2C+Albert&rft.aulast=Crutcher&rft.aufirst=Sihon&rft.date=2009-07-06&rft.volume=&rft.issue=&rft.spage=&rft.isbn=&rft.btitle=&rft.title=2009+Annual+Meeting+of+the+Society+for+Industrial+and+Applied+Mathematics&rft.issn=&rft_id=info:doi/ L2 - http://meetings.siam.org/program.cfm?CONFCODE=AN09 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2009-09-28 N1 - Last updated - 2010-05-03 ER - TY - JOUR T1 - Effects of exercise training on the matrix metalloprotease response to acute exercise AN - 954596281; 14082352 AB - Matrix metalloproteases (MMPs) in the circulation are thought to modulate the activation of growth factors, cytokines, and angiogenesis, facilitating physiological adaptations to exercise training. The purpose of this work was to characterize serum MMP-1, MMP-2, MMP-3, and MMP-9 concentrations pre- and post-eight weeks of exercise training. We tested the hypothesis that exercise training would influence serum MMP concentrations in response to an acute resistance exercise test (ARET). Participants were randomized into an 8-week training program (5days per week) that emphasized callisthenic (CT, N=8) or resistance (RT, N=8) exercise. Serum MMP concentrations (MMP-1, -2, -3, -9) were assessed in men (N=16) in response to an acute bout of high-intensity resistance exercise (six sets of 10-RM squats with 2-min inter-set rest periods) both before and after 8weeks of training. Training resulted in a temporal shift in the peak MMP-1 concentration from post-ARET to mid-ARET in both groups. Post-training, MMP-9 concentrations were increased immediately after the ARET in the CT group as compared to pre-training ARET concentrations. RT did not alter MMP-3 and -9 concentrations. These data suggest that the mode of exercise training influences the MMP response to an acute bout of exercise, revealing a possible role of MMPs in initiating training-specific adaptations. JF - European Journal of Applied Physiology AU - Urso, Maria L AU - Pierce, Joseph R AU - Alemany, Joseph A AU - Harman, Everett A AU - Nindl, Bradley C AD - Military Performance Division, U.S. Army Research Institute of Environmental Medicine, Building 42, Kansas Street, Natick, MA, 01760, USA, maria.urso@us.army.mil Y1 - 2009/07// PY - 2009 DA - Jul 2009 SP - 655 EP - 663 PB - Springer-Verlag, P.O. Box 2485 Secaucus NJ 07096-2485 USA VL - 106 IS - 5 SN - 1439-6319, 1439-6319 KW - Physical Education Index KW - Blood KW - Exercise physiology KW - Exercise (mode) KW - Men KW - Training (programs) KW - Rest KW - Work KW - Resistance exercise KW - Exercise (programs) KW - PE 030:Exercise, Health & Physical Fitness UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/954596281?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Aphysicaleducation&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=European+Journal+of+Applied+Physiology&rft.atitle=Effects+of+exercise+training+on+the+matrix+metalloprotease+response+to+acute+exercise&rft.au=Urso%2C+Maria+L%3BPierce%2C+Joseph+R%3BAlemany%2C+Joseph+A%3BHarman%2C+Everett+A%3BNindl%2C+Bradley+C&rft.aulast=Urso&rft.aufirst=Maria&rft.date=2009-07-01&rft.volume=106&rft.issue=5&rft.spage=655&rft.isbn=&rft.btitle=&rft.title=European+Journal+of+Applied+Physiology&rft.issn=14396319&rft_id=info:doi/10.1007%2Fs00421-009-1063-0 LA - English DB - Physical Education Index N1 - Date revised - 2012-03-01 N1 - Last updated - 2012-03-30 N1 - SubjectsTermNotLitGenreText - Blood; Exercise physiology; Exercise (mode); Men; Training (programs); Rest; Work; Resistance exercise; Exercise (programs) DO - http://dx.doi.org/10.1007/s00421-009-1063-0 ER - TY - JOUR T1 - Improved cell sensitivity and longevity in a rapid impedance-based toxicity sensor AN - 883025420; 15241901 AB - A number of toxicity sensors for testing field water using a range of eukaryotic cell types have been proposed, but it has been difficult to identify sensors with both appropriate sensitivity to toxicants and the potential for long-term viability. Assessment of bovine pulmonary artery endothelial cell (BPAEC) monolayer electrical impedance with electric cell-substrate impedance sensing (ECIS) showed promise in a previous systematic evaluation of toxicity sensor technologies. The goal of the study reported here was to improve toxicant responsiveness and field portability of this cell-based toxicity sensor. A variety of human cells, non-human mammalian cells, and non-mammalian vertebrate cells were screened for sensitivity to 12 waterborne industrial chemicals. The results of this assessment show that bovine lung microvessel endothelial cell (BLMVEC) monolayers and iguana heart (IgH-2) cell monolayers could detect nine out of the 12 waterborne industrial chemicals, an improvement over the seven chemicals previously detected using BPAEC monolayers. Both the BLMVEC and IgH-2 cell monolayers were tested for their ability for long-term survival on the ECIS test chips in a laboratory environment. Both cell lines were able to maintain high impedance readings on the ECIS electrodes for 37 days, a key trait in developing a field-portable toxicity sensor for water. Cell line optimization has greatly contributed to the on-going development of a field-portable cell-based biosensor that detects with sensitivity a wide range of waterborne toxicants. Published in 2009 by John Wiley & Sons, Ltd. JF - Journal of Applied Toxicology AU - Curtis, Theresa M AU - Tabb, Joel AU - Romeo, Lori AU - Schwager, Steven J AU - Widder, Mark W AU - van der Schalie, William H AD - Agave BioSystems, Inc., 401 E. State Street, Ithaca, NY 14850, USA, mark.widder@us.army.mil Y1 - 2009/07// PY - 2009 DA - Jul 2009 SP - 374 EP - 380 PB - Wiley-Blackwell, 111 River Street Hoboken NJ 07030-5774 United States VL - 29 IS - 5 SN - 1099-1263, 1099-1263 KW - Environment Abstracts; Toxicology Abstracts KW - Chemicals KW - toxicity testing KW - Heart KW - Cell survival KW - Sensitivity KW - Sensors KW - Toxicants KW - Toxicity KW - Electrical impedance KW - Longevity KW - Biosensors KW - Endothelial cells KW - Mammalian cells KW - Lung KW - Pulmonary artery KW - Electrodes KW - Iguana KW - Language KW - survival KW - longevity KW - X 24350:Industrial Chemicals KW - ENA 02:Toxicology & Environmental Safety UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/883025420?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxicologyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+Applied+Toxicology&rft.atitle=Improved+cell+sensitivity+and+longevity+in+a+rapid+impedance-based+toxicity+sensor&rft.au=Curtis%2C+Theresa+M%3BTabb%2C+Joel%3BRomeo%2C+Lori%3BSchwager%2C+Steven+J%3BWidder%2C+Mark+W%3Bvan+der+Schalie%2C+William+H&rft.aulast=Curtis&rft.aufirst=Theresa&rft.date=2009-07-01&rft.volume=29&rft.issue=5&rft.spage=374&rft.isbn=&rft.btitle=&rft.title=Journal+of+Applied+Toxicology&rft.issn=10991263&rft_id=info:doi/10.1002%2Fjat.1421 L2 - http://onlinelibrary.wiley.com/doi/10.1002/jat.1421/abstract LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2011-08-01 N1 - Last updated - 2015-03-19 N1 - SubjectsTermNotLitGenreText - Cell survival; Heart; Toxicants; Toxicity; Electrical impedance; Longevity; Endothelial cells; Biosensors; Mammalian cells; Lung; Pulmonary artery; Electrodes; Language; toxicity testing; Chemicals; Sensitivity; Sensors; longevity; survival; Iguana DO - http://dx.doi.org/10.1002/jat.1421 ER - TY - JOUR T1 - Comparison of Short-Term Response to Two Spinal Manipulation Techniques for Patients With Low Back Pain in a Military Beneficiary Population AN - 744701651; 13156097 AB - ABSTRACT Objective: To determine whether military health care beneficiaries with low back pain (LBP) who are likely to respond successfully to spinal manipulation experience a difference in short-term clinical outcomes based on the manipulation technique that is used. Methods: Sixty patients with LBP identified as likely responders to manipulation underwent a standardized clinical examination and were randomized to receive a lumbopelvic (LP) or lumbar neutral gap (NG) manipulation technique. Outcome measures were a numeric pain rating scale and the modified Oswestry Disability Questionnaire. Results: Both the LP and NG groups experienced statistically significant reductions in pain and disability at 48 hours postmanipulation. The improvements seen in each group were small because of the short follow-up. There were no statistically significant or clinically meaningful differences in pain or disability between the two groups. Conclusion: The two manipulation techniques used in this study were equally effective at reducing pain and disability when compared at 48 hours posttreatment. Clinicians may employ either technique for the treatment of LBP and can expect similar outcomes in those who satisfy the clinical prediction rule (CPR). Further research is required to determine whether differences exist at longer-term follow-up periods, after multiple treatment sessions, or in different clinical populations. JF - Military Medicine AU - Sutlive, Thomas G AU - Mabry, Lance M AU - Easterling, Emmanuel J AU - Durbin, Jose D AU - Hanson, Stephen L AU - Wainner, Robert S AU - Childs, John D AD - U.S. Army-Baylor University Doctoral Program in Physical Therapy, 3151 Scott Road, Suite 1303, Fort Sam Houston, TX 78234. Y1 - 2009/07// PY - 2009 DA - Jul 2009 SP - 750 EP - 756 PB - Association of Military Surgeons of the US, 9320 Old Georgetown Road Bethesda, MD 20814 USA VL - 174 IS - 7 SN - 0026-4075, 0026-4075 KW - Health & Safety Science Abstracts KW - disabilities KW - Health care KW - low back pain KW - Standards KW - Military KW - H 1000:Occupational Safety and Health UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/744701651?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Ahealthsafetyabstracts&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Military+Medicine&rft.atitle=Comparison+of+Short-Term+Response+to+Two+Spinal+Manipulation+Techniques+for+Patients+With+Low+Back+Pain+in+a+Military+Beneficiary+Population&rft.au=Sutlive%2C+Thomas+G%3BMabry%2C+Lance+M%3BEasterling%2C+Emmanuel+J%3BDurbin%2C+Jose+D%3BHanson%2C+Stephen+L%3BWainner%2C+Robert+S%3BChilds%2C+John+D&rft.aulast=Sutlive&rft.aufirst=Thomas&rft.date=2009-07-01&rft.volume=174&rft.issue=7&rft.spage=750&rft.isbn=&rft.btitle=&rft.title=Military+Medicine&rft.issn=00264075&rft_id=info:doi/ L2 - http://www.ingentaconnect.com/content/amsus/zmm/2009/00000174/00000007/art00023 LA - English DB - ProQuest Environmental Science Collection N1 - Date revised - 2010-07-01 N1 - Last updated - 2011-12-14 N1 - SubjectsTermNotLitGenreText - Health care; disabilities; low back pain; Standards; Military ER - TY - JOUR T1 - Perioperative immunonutrition in head and neck cancer. AN - 742778958; pmid-19459146 AB - OBJECTIVES/HYPOTHESIS: Immune-modulating nutrition (IMN) support before and after surgery has the potential to promote host defense, antitumor activities, and wound healing. The purpose of this study was to examine the nutritional, immunologic, and wound healing outcomes in patients receiving IMN versus standard formula. STUDY DESIGN: A prospective, blinded, randomized design was used for this study. Fifteen patients with head and neck squamous cell carcinoma received either an IMN formula (treatment group) or a standard stress formula (relative comparison group [RCG]) for a period of 7 days pre- and postoperatively. METHODS: Albumin and prealbumin were measured at baseline, day of surgery (DOS), and postoperative day (POD) 1, 4, and 8. Immunologic outcomes included C-reactive protein and total lymphocyte count with lymphocyte subset counts (CD3, CD4, CD8, CD4:8 ratio, CD19, CD56) at baseline, DOS, POD1, 4, and 8. Cell-mediated immunity was evaluated by delayed-type hypersensitivity. Wound healing was assessed using the ASEPSIS tool. RESULTS: CD3+ and CD4+ T cells demonstrated a significant difference between groups on POD 1 (P = .03 for both) and CD56 NK cells on POD 8 (P = .04). In general, wounds healed without complications except for tracheoesophageal fistula development in two patients in the RCG. CONCLUSIONS: A trend toward less immune suppression in patients receiving IMN is supported in this study. JF - The Laryngoscope AU - Sorensen, Douglas AU - McCarthy, Mary AU - Baumgartner, Brian AU - Demars, Sean AD - Department of Surgery, Otolaryngology-Head and Neck Surgery Service, Madigan Army Medical Center, Tacoma, Washington 98431, USA. douglas.sorensen@us.army.mil Y1 - 2009/07// PY - 2009 DA - Jul 2009 SP - 1358 EP - 1364 VL - 119 IS - 7 SN - 0023-852X, 0023-852X KW - Index Medicus KW - National Library of Medicine KW - Analysis of Variance KW - Prospective Studies KW - Humans KW - Wound Healing -- drug effects KW - Treatment Outcome KW - Aged KW - Middle Aged KW - Postoperative Period KW - Male KW - Female KW - Carcinoma, Squamous Cell -- surgery KW - Carcinoma, Squamous Cell -- immunology KW - Food, Formulated KW - Head and Neck Neoplasms -- surgery KW - Nutritional Status -- immunology KW - Head and Neck Neoplasms -- immunology UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/742778958?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Acomdisdome&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=The+Laryngoscope&rft.atitle=Perioperative+immunonutrition+in+head+and+neck+cancer.&rft.au=Sorensen%2C+Douglas%3BMcCarthy%2C+Mary%3BBaumgartner%2C+Brian%3BDemars%2C+Sean&rft.aulast=Sorensen&rft.aufirst=Douglas&rft.date=2009-07-01&rft.volume=119&rft.issue=7&rft.spage=1358&rft.isbn=&rft.btitle=&rft.title=The+Laryngoscope&rft.issn=0023852X&rft_id=info:doi/ LA - English (eng) DB - ComDisDome N1 - Date revised - 2010-04-13 N1 - Last updated - 2010-09-25 ER - TY - JOUR T1 - Perspectives on ecological risk assessment of chiral compounds. AN - 734220220; 20050025 AB - Enantiomers of chiral contaminants can significantly differ in environmental fate as well as in effects. Despite this fact, such differences are often ignored in regulation and in practice, injecting uncertainty into the estimation of risk of chiral compounds. We review the unique challenges posed by stereochemistry to the ecological risk assessment of chiral contaminants and existing regulatory guidance for chiral pharmaceuticals and pesticides in the United States. We identify the advantages of obtaining data on fate and effects of each individual enantiomer of chiral contaminants that are either distributed as or may end up as enantiomer mixtures in the environment due to enantiomerization. Because enantiomers of the same compound are highly likely to coexist in the environment with each other and can result in nonadditive effects, we recommend treatment of enantiomers as components of a mixture using widely accepted mixture models from achiral risk assessment. We further propose the enantiomer hazard ratio for retrospectively characterizing relative enantiomer risk and examine uncertainty factor magnitudes for effects analysis. JF - Integrated environmental assessment and management AU - Stanley, Jacob K AU - Brooks, Bryan W AD - Baylor University, Department of Environmental Science, Center for Reservoir and Aquatic Systems Research, One Bear Place #97266, Waco, Texas 76798, USA. jacob.k.stanley@us.army.mil Y1 - 2009/07// PY - 2009 DA - July 2009 SP - 364 EP - 373 VL - 5 IS - 3 KW - Pesticides KW - 0 KW - Index Medicus KW - Molecular Structure KW - Environmental Monitoring KW - Risk Factors KW - Risk Assessment KW - Pesticides -- chemistry KW - Environmental Exposure KW - Pesticides -- toxicity UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/734220220?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Integrated+environmental+assessment+and+management&rft.atitle=Perspectives+on+ecological+risk+assessment+of+chiral+compounds.&rft.au=Stanley%2C+Jacob+K%3BBrooks%2C+Bryan+W&rft.aulast=Stanley&rft.aufirst=Jacob&rft.date=2009-07-01&rft.volume=5&rft.issue=3&rft.spage=364&rft.isbn=&rft.btitle=&rft.title=Integrated+environmental+assessment+and+management&rft.issn=1551-3793&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2010-01-05 N1 - Date created - 2009-12-14 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Typing methods for the plague pathogen, Yersinia pestis. AN - 67616117; 19714987 AB - Phenotypic and genotypic methodologies have been used to differentiate the etiological agent of plague, Yersinia pestis. Historically, phenotypic methods were used to place isolates into one of three biovars based on nitrate reduction and glycerol fermentation. Classification of Y. pestis into genetic subtypes is problematic due to the relative monomorphic nature of the pathogen. Resolution into groups is dependent on the number and types of loci used in the analysis. The last 5-10 years of research and analysis in the field of Y. pestis genotyping have resulted in a recognition by Western scientists that two basic types of Y. pestis exist. One type, considered to be classic strains that are able to cause human plague transmitted by the normal flea vector, is termed epidemic strains. The other type does not typically cause human infections by normal routes of infection, but is virulent for rodents and is termed endemic strains. Previous classification schemes used outside the Western hemisphere referred to these latter strains as Pestoides varieties of Y. pestis. Recent molecular analysis has definitely shown that both endemic and epidemic strains arose independently from a common Yersinia pseudotuberculosis ancestor. Currently, 11 major groups of Y. pestis are defined globally. JF - Journal of AOAC International AU - Lindler, Luther E AD - Department of Defense, Global Emerging Infections Surveillance and Response System, Armed Forces Health Surveillance Center, 2900 Linden Ln, Silver Spring, MD 20910, USA. Luther.Lindler@us.army.mil PY - 2009 SP - 1174 EP - 1183 VL - 92 IS - 4 SN - 1060-3271, 1060-3271 KW - RNA, Bacterial KW - 0 KW - Index Medicus KW - Ribotyping KW - RNA, Bacterial -- analysis KW - Polymorphism, Single Nucleotide KW - Biological Evolution KW - Humans KW - RNA, Bacterial -- genetics KW - Reverse Transcriptase Polymerase Chain Reaction KW - Yersinia pseudotuberculosis -- genetics KW - Genotype KW - Minisatellite Repeats KW - Phenotype KW - Electrophoresis, Gel, Pulsed-Field KW - Russia KW - Madagascar KW - Mutagenesis, Insertional KW - Plague -- microbiology KW - Yersinia pestis -- genetics KW - Plague -- transmission KW - Yersinia pestis -- classification UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67616117?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Journal+of+AOAC+International&rft.atitle=Typing+methods+for+the+plague+pathogen%2C+Yersinia+pestis.&rft.au=Lindler%2C+Luther+E&rft.aulast=Lindler&rft.aufirst=Luther&rft.date=2009-07-01&rft.volume=92&rft.issue=4&rft.spage=1174&rft.isbn=&rft.btitle=&rft.title=Journal+of+AOAC+International&rft.issn=10603271&rft_id=info:doi/ LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-09-24 N1 - Date created - 2009-08-31 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 ER - TY - JOUR T1 - Inactivation of virulent Burkholderia pseudomallei by sunlight. AN - 67449819; 19192198 AB - The goal of this study was to determine the sensitivity of virulent Burkholderia pseudomallei to natural sunlight. We describe solar dosimetry calibrated to integrate radiation between 295 and 305 nm and an exposure system that minimizes thermal effects on bacterial cells. Burkholderia pseudomallei cells were either exposed to sunlight in UV transparent dishes or maintained in the dark covered by opaque foil. The cells maintained in the dark remained at constant levels for the duration of all experiments. The exposed cells nearby were killed with a kinetic studied through 5 Log10 inactivation. We found that cells in stationary phase of growth were nearly two-fold more resistant to sunlight than cells in lag or exponential growth. A virulent strain of B. pseudomallei that produced mucoid colonies showed sensitivity to sunlight similar to both a virulent strain that produced nonmucoid colonies and a strain of B. thailandensis. The inactivation of B. pseudomallei by sunlight in different types of water of environmental relevance or inside amoebae was investigated. The sensitivity of virulent B. pseudomallei was calculated and its comparison with previous studies employing monochromatic germicidal light (254 nm) is discussed. This may be the first report in the open literature of the inactivation of a virulent biological threat agent by natural sunlight. These data should assist in estimating the risk for contracting melioidosis and in predicting the time period during which B. pseudomallei remains infectious after an accidental or intentional release in the environment. JF - Photochemistry and photobiology AU - Sagripanti, Jose-Luis AU - Levy, Avram AU - Robertson, Jeannie AU - Merritt, Adam AU - Inglis, Timothy J J AD - Edgewood Chemical Biological Center, US Army, Aberdeen Proving Ground, MD, USA. joseluis.sagripanti@us.army.mil PY - 2009 SP - 978 EP - 986 VL - 85 IS - 4 SN - 0031-8655, 0031-8655 KW - Index Medicus KW - Dose-Response Relationship, Radiation KW - Virus Inactivation KW - Virulence KW - Burkholderia pseudomallei -- pathogenicity KW - Sunlight KW - Burkholderia pseudomallei -- radiation effects UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67449819?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&rfr_id=info:sid/ProQ%3Atoxline&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.jtitle=Photochemistry+and+photobiology&rft.atitle=Inactivation+of+virulent+Burkholderia+pseudomallei+by+sunlight.&rft.au=Sagripanti%2C+Jose-Luis%3BLevy%2C+Avram%3BRobertson%2C+Jeannie%3BMerritt%2C+Adam%3BInglis%2C+Timothy+J+J&rft.aulast=Sagripanti&rft.aufirst=Jose-Luis&rft.date=2009-07-01&rft.volume=85&rft.issue=4&rft.spage=978&rft.isbn=&rft.btitle=&rft.title=Photochemistry+and+photobiology&rft.issn=00318655&rft_id=info:doi/10.1111%2Fj.1751-1097.2008.00518.x LA - English DB - ProQuest Environmental Science Collection N1 - Date completed - 2009-09-03 N1 - Date created - 2009-07-03 N1 - Date revised - 2017-01-13 N1 - Last updated - 2017-01-18 DO - http://dx.doi.org/10.1111/j.1751-1097.2008.00518.x ER - TY - JOUR T1 - Pathology of inhalational Francisella tularensis spp. tularensis SCHU S4 infection in African green monkeys (Chlorocebus aethiops). AN - 67434286; 19276059 AB - Tularemia, caused by Francisella tularensis, is a sporadic zoonotic disease with the potential to be an agent of biowarfare or bioterrorism. We describe here the gross, histologic, immunohistochemical, and ultrastructural findings in a group of 5 African green monkeys (AGMs) that received an average inhaled dose of 729 colony-forming units of F. tularensis and died or were euthanatized between days 7 and 11 post infection. Clinical changes were evident by 48 hours post infection, and key physiologic abnormalities included increases in body temperature, heart rate, peak cardiac pressure, and mean blood pressure. Prominent gross changes in all cases included numerous pinpoint to 1-cm, well-demarcated, necrotic foci present consistently in the lungs, mediastinal lymph nodes, and spleen but also seen in the heart, mediastinum, diaphragm, liver, urinary bladder, urethra, and mesentery. The lungs, mediastinal lymph nodes, and spleen were most severely affected, with as much as 50% of the tissue replaced by necrotic foci. Histologic changes in all tissues consisted of well-delineated foci of necrosis and neutrophilic and histiocytic inflammation, with varying amounts of hemorrhage, edema, fibrin, and vasculitis. Some lesions were immature pyogranulomas. Strong immunoreactivity was identified primarily within macrophages. Ultrastructurally, bacteria were present within cytoplasmic vacuoles of alveolar macrophages, many of which were degenerate. In summary, AGMs infected with F. tularensis by aerosol develop lethal multisystemic disease that particularly targets the lungs and lymphoid tissues. Thus, AGMs should serve as a suitable and reliable animal model for further studies of tularemia. JF - Veterinary pathology AU - Twenhafel, N A AU - Alves, D A AU - Purcell, B K AD - United States Army Medical Research Institute of Infectious Diseases, Pathology Division, Fort Detrick, MD 21702, USA. nancy.twenhafel@us.army.mil Y1 - 2009/07// PY - 2009 DA - July 2009 SP - 698 EP - 706 VL - 46 IS - 4 KW - Index Medicus KW - Viscera -- pathology KW - Animals KW - Vacuoles -- ultrastructure KW - Heart Rate KW - Body Temperature KW - Blood Pressure KW - Microscopy, Electron, Transmission -- veterinary KW - Microscopy, Immunoelectron -- veterinary KW - Vacuoles -- microbiology KW - Immunohistochemistry -- veterinary KW - Male KW - Monkey Diseases -- transmission KW - Inhalation Exposure KW - Cercopithecus aethiops KW - Tularemia -- veterinary KW - Francisella tularensis KW - Tularemia -- pathology KW - Monkey Diseases -- pathology KW - Monkey Diseases -- microbiology KW - Tularemia -- transmission UR - http://libproxy.lib.unc.edu/login?url=http://search.proquest.com/docview/67434286?accountid=14244 L2 - http://vb3lk7eb4t.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/