{"indexed":{"date-parts":[[2017,10,27]],"date-time":"2017-10-27T18:39:56Z","timestamp":1509129596382},"reference-count":12,"publisher":"Cambridge University Press (CUP)","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:sec id=\"S0899823X15002457_abs1\" sec-type=\"objectives\">\n               <jats:title>OBJECTIVES<\/jats:title>\n               <jats:p>To determine the impact of mucosal barrier injury laboratory-confirmed bloodstream infections (MBI-LCBIs) on central-line\u2013associated bloodstream infection (CLABSI) rates during the first year of MBI-LCBI reporting to the National Healthcare Safety Network (NHSN)<\/jats:p>\n            <\/jats:sec>\n            <jats:sec id=\"S0899823X15002457_abs2\" sec-type=\"general\">\n               <jats:title>DESIGN<\/jats:title>\n               <jats:p>Descriptive analysis of 2013 NHSN data<\/jats:p>\n            <\/jats:sec>\n            <jats:sec id=\"S0899823X15002457_abs3\" sec-type=\"general\">\n               <jats:title>SETTING<\/jats:title>\n               <jats:p>Selected inpatient locations in acute care hospitals<\/jats:p>\n            <\/jats:sec>\n            <jats:sec id=\"S0899823X15002457_abs4\" sec-type=\"methods\">\n               <jats:title>METHODS<\/jats:title>\n               <jats:p>A descriptive analysis of MBI-LCBI cases was performed. CLABSI rates per 1,000 central-line days were calculated with and without the inclusion of MBI-LCBIs in the subset of locations reporting \u22651 MBI-LCBI, and in all locations (regardless of MBI-LCBI reporting) to determine rate differences overall and by location type.<\/jats:p>\n            <\/jats:sec>\n            <jats:sec id=\"S0899823X15002457_abs5\" sec-type=\"results\">\n               <jats:title>RESULTS<\/jats:title>\n               <jats:p>From 418 locations in 252 acute care hospitals reporting \u22651 MBI-LCBIs, 3,162 CLABSIs were reported; 1,415 (44.7%) met the MBI-LCBI definition. Among these locations, removing MBI-LCBI from the CLABSI rate determination produced the greatest CLABSI rate decreases in oncology (49%) and ward locations (45%). Among all locations reporting CLABSI data, including those reporting no MBI-LCBIs, removing MBI-LCBI reduced rates by 8%. Here, the greatest decrease was in oncology locations (38% decrease); decreases in other locations ranged from 1.2% to 4.2%.<\/jats:p>\n            <\/jats:sec>\n            <jats:sec id=\"S0899823X15002457_abs6\" sec-type=\"conclusions\">\n               <jats:title>CONCLUSIONS<\/jats:title>\n               <jats:p>An understanding of the potential impact of removing MBI-LCBIs from CLABSI data is needed to accurately interpret CLABSI trends over time and to inform changes to state and federal reporting programs. Whereas the MBI-LCBI definition may have a large impact on CLABSI rates in locations where patients with certain clinical conditions are cared for, the impact of MBI-LCBIs on overall CLABSI rates across inpatient locations appears to be more modest.<\/jats:p>\n               <jats:p>\n                  <jats:italic>Infect. Control Hosp. Epidemiol.<\/jats:italic> 2015;37(1):2\u20137<\/jats:p>\n            <\/jats:sec>","DOI":"10.1017\/ice.2015.245","type":"article-journal","created":{"date-parts":[[2015,10,12]],"date-time":"2015-10-12T22:42:22Z","timestamp":1444689742000},"page":"2-7","source":"Crossref","is-referenced-by-count":3,"title":"Mucosal Barrier Injury Laboratory-Confirmed Bloodstream Infections (MBI-LCBI): Descriptive Analysis of Data Reported to National Healthcare Safety Network (NHSN), 2013","prefix":"10.1017","volume":"37","author":[{"given":"Lauren","family":"Epstein","affiliation":[]},{"given":"Isaac","family":"See","affiliation":[]},{"given":"Jonathan R.","family":"Edwards","affiliation":[]},{"given":"Shelley S.","family":"Magill","affiliation":[]},{"given":"Nicola D.","family":"Thompson","affiliation":[]}],"member":"56","published-online":{"date-parts":[[2015,10,12]]},"reference":[{"key":"S0899823X15002457_ref9","DOI":"10.1093\/infdis\/152.1.99","doi-asserted-by":"publisher"},{"key":"S0899823X15002457_ref8","DOI":"10.1002\/cncr.22527","doi-asserted-by":"publisher"},{"key":"S0899823X15002457_ref7","DOI":"10.1086\/667380","doi-asserted-by":"publisher"},{"key":"S0899823X15002457_ref18","DOI":"10.1016\/j.ajic.2014.11.014","doi-asserted-by":"publisher"},{"key":"S0899823X15002457_ref5","DOI":"10.1086\/657583","doi-asserted-by":"publisher"},{"key":"S0899823X15002457_ref10","DOI":"10.1038\/sj.bmt.1702447","doi-asserted-by":"publisher"},{"key":"S0899823X15002457_ref4","DOI":"10.1086\/669082","doi-asserted-by":"publisher"},{"key":"S0899823X15002457_ref16","DOI":"10.1086\/668431","doi-asserted-by":"publisher"},{"key":"S0899823X15002457_ref3","DOI":"10.1093\/cid\/cir200","doi-asserted-by":"publisher"},{"key":"S0899823X15002457_ref15","DOI":"10.1086\/669513","doi-asserted-by":"publisher"},{"key":"S0899823X15002457_ref12","DOI":"10.1086\/671281","doi-asserted-by":"publisher"},{"key":"S0899823X15002457_ref17","DOI":"10.1017\/ice.2014.38","doi-asserted-by":"publisher"}],"container-title":"Infection Control & Hospital Epidemiology","original-title":[],"link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0899823X15002457","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,4,22]],"date-time":"2017-04-22T20:00:09Z","timestamp":1492891209000},"score":1.0,"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10,12]]},"references-count":12,"alternative-id":["S0899823X15002457"],"URL":"http:\/\/dx.doi.org\/10.1017\/ice.2015.245","relation":{"cites":[]},"ISSN":["0899-823X","1559-6834"],"subject":["Microbiology (medical)","Epidemiology","Infectious Diseases"],"container-title-short":"Infect. Control Hosp. Epidemiol."}